Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCA7 ABCX ENSG00000064687 "ATP binding cassette subfamily A member 7" Q8IZY2 19 1039997-1065572 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Phagocytosis, Transport" Translocase "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.4;pituitary gland: 28.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Bipolar cells: 70.6;Cone photoreceptor cells: 175.2;Extravillous trophoblasts: 303.3;Rod photoreceptor cells: 149.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 20.4;HMC-1: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA041564 Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Plasma membrane" "Cell Junctions" "HPA041564: AB_2677550" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (7.26e-4)" "prognostic favorable (1.12e-4)" "unprognostic (8.88e-2)" "unprognostic (1.13e-2)" "unprognostic (2.25e-1)" "unprognostic (4.00e-2)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "unprognostic (1.51e-3)" "unprognostic (3.68e-2)" "unprognostic (8.99e-3)" "unprognostic (2.08e-2)" "unprognostic (3.66e-1)" "unprognostic (7.88e-2)" "unprognostic (7.85e-2)" 4.4 3.0 3.4 5.5 3.9 27.4 3.3 4.0 6.1 3.2 11.5 3.8 2.3 1.2 0.2 7.6 2.1 2.1 3.1 3.6 3.7 6.4 4.2 9.5 8.5 5.8 4.5 0.5 7.7 2.7 28.7 1.2 5.3 5.3 1.2 25.5 8.6 1.1 3.8 5.9 10.1 0.5 3.0 26.6 3.8 1.7 4.1 10.0 5.7 0.3 3.2 2.3 2.8 3.2 4.7 6.4 0.5 4.4 7.2 2.2 7.3 0.8 1.0 0.4 0.6 5.2 2.8 13.9 5.6 1.3 0.6 8.0 1.3 6.2 0.4 10.2 2.5 6.7 20.4 5.6 1.8 3.9 40.3 3.8 1.8 0.9 1.2 4.4 1.4 7.7 10.2 6.9 1.3 2.2 4.3 2.2 0.9 3.3 2.5 3.1 0.8 11.6 3.8 6.0 0.3 1.3 8.2 1.9 1.2 1.1 4.6 7.1 2.2 0.4 1.6 3.7 0.8 9.9 6.6 5.7 2.1 7.4 2.0 2.8 1.4 5.9 1.8 1.2 1.1 0.6 0.9 1.2 2.1 0.9 0.8 1.5 3.3 1.1 1.3 7.3 0.4 1.3 3.4 3.9 4.0 6.1 3.6 3.7 5.8 4.5 5.3 3.0 4.1 3.2 4.1 73.7 21.9 8.5 13.2 3.3 0.8 10.7 5.2 70.6 4.8 2.2 6.0 4.3 14.0 5.5 175.2 4.6 9.1 14.7 1.9 2.7 7.3 8.9 1.4 2.9 3.5 13.3 12.9 2.5 303.3 1.5 5.6 6.9 10.1 2.0 2.5 4.9 7.9 15.2 11.5 4.7 16.2 12.6 7.5 4.8 0.0 12.7 0.0 4.7 19.6 13.1 9.2 1.5 2.4 7.0 9.6 0.0 12.0 1.5 1.7 1.3 17.5 149.1 0.0 2.7 2.7 0.7 2.0 6.6 3.4 25.7 12.6 1.0 5.3 1.9 ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401696-87480435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 123.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 256.1" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 4.4;naive B-cell: 8.1" "Lineage enriched" "Detected in many" 7 "B-cells: 8.1" "Group enriched" "Detected in some" 5 "SH-SY5Y: 12.9;WM-115: 25.7" "Low region specificity" "Detected in many" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Plasma membrane, Actin filaments" "Focal adhesion sites" "HPA049395: AB_2680745, HPA053288: AB_2682102" "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" 0.7 7.4 0.8 2.5 0.6 0.9 0.5 0.6 0.9 0.3 0.4 1.1 0.4 0.2 0.6 0.6 0.2 0.8 6.6 0.8 0.6 0.6 123.2 0.2 5.9 0.9 0.6 0.4 0.1 0.0 0.2 0.2 1.0 0.5 1.2 0.4 0.6 0.4 7.5 1.4 2.1 0.3 0.6 5.0 0.6 1.0 0.7 0.7 0.5 4.8 5.2 1.2 0.5 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 12.9 0.0 0.6 2.6 0.5 0.2 0.6 0.0 0.2 1.7 0.1 0.0 0.0 0.0 3.2 0.2 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.2 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.8 0.6 0.6 0.9 0.8 0.6 0.9 0.6 1.0 0.6 0.7 0.7 1.3 0.0 0.5 0.3 22.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 1.8 0.0 1.1 0.1 0.2 0.0 0.1 0.6 0.2 0.2 1.0 0.0 0.4 0.6 0.0 0.3 2.0 0.0 0.2 0.0 0.0 3.3 256.1 0.5 38.7 1.8 0.0 0.0 5.0 1.2 0.4 0.0 1.0 10.6 3.7 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.4 0.3 0.0 0.5 0.7 0.0 0.2 0.0 0.6 1.2 1.2 0.2 0.0 0.4 0.1 0.7 0.0 0.2 0.0 ABCB6 "EST45597, MTABC3, umat" ENSG00000115657 "ATP binding cassette subfamily B member 6 (Langereis blood group)" Q9NP58 2 219209772-219218994 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Dyskeratosis congenita, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 14.7;Excitatory neurons: 12.9;Gastric mucus-secreting cells: 5.1;Inhibitory neurons: 10.9;Oligodendrocyte precursor cells: 13.6;Oligodendrocytes: 5.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 65.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046723, HPA058011" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Nucleoplasm, Plasma membrane, Mitochondria, Cytosol" "HPA046723: AB_10960288, HPA058011: AB_2683578" "unprognostic (8.04e-2)" "unprognostic (3.22e-2)" "unprognostic (4.53e-3)" "unprognostic (3.19e-2)" "unprognostic (2.55e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (9.45e-7)" "unprognostic (2.26e-1)" "unprognostic (3.62e-2)" "unprognostic (1.53e-1)" "unprognostic (1.18e-4)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.51e-1)" "unprognostic (9.55e-2)" "unprognostic (7.75e-2)" "unprognostic (2.30e-1)" 10.2 8.7 4.3 3.4 3.9 10.4 7.6 3.2 4.6 7.7 4.4 6.5 6.9 8.4 8.2 11.4 9.6 7.1 8.5 4.0 5.1 5.2 15.9 5.9 1.9 4.4 4.2 12.9 5.7 4.8 6.0 3.1 6.2 8.0 3.3 3.0 6.2 8.6 30.4 6.8 6.3 7.9 4.1 3.9 7.9 18.0 5.7 2.6 10.7 9.8 2.9 14.9 7.9 5.0 0.3 22.9 4.7 28.8 30.8 11.1 27.6 8.5 7.9 9.2 9.2 35.5 5.0 0.3 42.8 8.6 5.0 49.1 0.6 3.6 3.0 15.0 4.7 36.3 24.9 65.8 37.0 0.0 12.0 16.3 4.2 6.2 0.1 13.9 16.3 4.8 31.4 4.4 6.3 12.0 2.3 0.1 7.2 53.6 9.2 12.3 14.3 1.6 5.1 0.4 16.6 17.8 17.6 41.4 18.7 17.4 12.4 0.8 7.5 12.5 0.5 16.9 10.3 11.2 9.6 0.1 14.0 0.4 17.0 0.7 0.4 0.0 0.7 0.4 0.2 1.0 0.5 0.2 0.3 0.8 1.2 0.8 0.0 0.4 0.3 2.3 0.5 1.0 4.3 3.9 3.2 4.6 4.0 5.1 4.4 4.2 6.2 4.1 5.7 5.0 0.2 0.0 0.0 14.7 0.3 0.3 0.0 0.5 1.2 1.0 0.2 0.0 0.2 0.0 1.3 0.0 0.0 0.2 0.2 0.1 0.0 0.8 1.2 0.3 0.6 0.4 0.0 1.3 12.9 0.0 0.1 0.7 5.1 0.2 0.0 0.5 0.0 0.4 0.1 0.0 10.9 0.3 0.0 0.3 0.4 1.0 0.3 0.3 0.0 3.7 0.0 0.3 0.0 13.6 5.6 0.3 0.0 0.4 0.5 0.0 0.5 0.2 2.2 0.8 0.0 0.4 0.3 1.0 0.3 2.8 0.3 0.3 0.1 0.4 0.2 0.1 ABCC1 "GS-X, MRP, MRP1" ENSG00000103222 "ATP binding cassette subfamily C member 1" P33527 16 15949138-16143257 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport "Hydrolase, Translocase" "Cancer-related genes, Deafness, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 79.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002380, HPA076011" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions" "HPA002380: AB_1844432, HPA076011: " "unprognostic (9.97e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (5.42e-5)" "unprognostic (3.42e-1)" "unprognostic (3.31e-1)" "unprognostic (4.07e-2)" "unprognostic (9.78e-3)" "unprognostic (7.19e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.84e-1)" "unprognostic (1.15e-1)" "unprognostic (1.43e-2)" "unprognostic (1.80e-2)" 10.4 11.6 0.3 4.0 0.2 3.6 8.6 0.3 0.7 10.4 4.1 16.1 1.1 11.0 0.1 22.8 7.0 3.1 11.2 0.3 0.5 8.0 2.3 15.5 4.4 1.1 0.8 8.9 8.9 3.6 7.2 2.0 0.7 15.2 0.7 0.4 9.2 0.9 21.2 9.7 12.4 6.3 0.5 15.7 15.0 13.1 0.6 4.3 21.0 0.1 1.1 15.4 12.8 0.9 4.3 43.7 0.3 11.7 3.2 4.5 0.5 15.4 19.0 13.1 13.8 6.7 34.8 7.0 79.6 29.6 11.0 12.1 3.4 12.4 4.6 22.2 4.4 16.4 22.0 16.3 25.1 5.9 39.5 15.0 9.0 1.1 2.3 3.8 10.2 28.6 17.8 6.8 0.5 5.4 12.0 0.9 3.5 1.8 8.2 41.9 7.8 5.3 0.7 15.2 6.4 11.8 18.9 17.8 3.6 11.9 6.2 0.8 3.5 0.4 2.0 11.4 11.9 13.5 7.4 3.3 6.6 0.6 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.7 0.3 0.5 1.1 0.8 0.7 0.5 0.6 0.9 8.6 25.6 5.6 10.7 13.1 8.8 8.5 18.2 9.6 3.1 4.4 3.7 6.0 4.3 14.4 5.5 22.9 0.9 9.8 2.7 3.9 9.1 11.0 15.7 12.9 8.6 18.6 16.0 26.6 6.2 3.2 12.3 49.5 17.8 22.1 16.8 8.6 0.4 8.5 5.0 38.5 6.6 14.2 21.4 9.1 14.3 7.5 12.2 3.6 11.2 10.5 1.2 5.2 12.1 15.9 11.2 4.5 6.8 15.7 18.7 0.5 1.1 9.9 8.8 0.0 6.4 5.1 4.9 6.6 18.1 5.1 0.5 17.4 37.1 3.7 11.6 ABCC3 "cMOAT2, EST90757, MLP2, MOAT-D, MRP3" ENSG00000108846 "ATP binding cassette subfamily C member 3" O15438 17 50634777-50692253 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 59.1;liver: 50.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 231.6;Distal enterocytes: 265.1;Gastric mucus-secreting cells: 271.7;Hepatocytes: 192.9;Paneth cells: 194.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.1;non-classical monocyte: 6.4" "Lineage enriched" "Detected in many" 5 "monocytes: 6.4" "Cell line enhanced" "Detected in many" "A549: 79.4;CAPAN-2: 60.6;HeLa: 36.9;OE19: 89.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB037136, HPA048483" Enhanced Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB037136: AB_477165, HPA048483: AB_2680414" "unprognostic (1.57e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.65e-2)" "unprognostic (9.67e-3)" "unprognostic (6.19e-3)" "unprognostic (7.44e-3)" "unprognostic (8.20e-2)" "unprognostic (3.18e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.60e-3)" "prognostic unfavorable (4.68e-6)" "unprognostic (3.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.44e-2)" "unprognostic (1.57e-3)" 3.1 59.1 0.1 3.4 1.8 0.8 4.2 0.2 0.7 2.1 0.0 18.9 12.0 1.1 1.8 7.5 1.0 11.9 0.9 0.3 0.3 8.0 50.4 4.8 1.9 5.9 0.8 0.7 22.6 0.8 0.8 1.1 3.5 5.9 8.7 0.4 7.0 5.5 0.2 7.1 11.9 1.3 1.7 3.4 17.1 1.0 2.5 0.3 5.5 0.0 1.7 6.3 3.6 2.4 5.7 79.4 0.0 0.3 4.4 6.9 0.1 10.4 13.1 0.7 0.7 4.2 60.6 0.0 8.0 20.6 14.5 14.5 0.0 1.0 1.0 0.0 0.0 1.7 36.9 24.2 17.2 0.0 0.0 7.5 5.6 2.9 6.2 8.5 1.4 0.0 0.2 0.0 8.0 18.9 0.0 0.0 0.1 89.7 10.1 0.1 0.0 0.3 33.4 34.2 0.1 0.6 19.2 3.1 0.0 0.1 2.6 0.0 17.3 0.5 3.4 0.2 8.5 0.1 0.0 0.0 8.2 0.0 0.9 0.2 2.3 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.3 6.4 0.1 0.5 5.4 0.1 1.8 0.2 0.7 0.3 0.3 5.9 0.8 3.5 1.7 2.5 2.4 0.7 19.2 5.5 0.0 1.8 9.4 122.2 47.1 42.7 1.6 1.9 6.9 3.1 231.6 19.5 14.7 0.0 0.4 0.0 265.1 5.9 100.1 82.9 5.9 8.8 2.7 23.5 0.0 4.3 106.1 3.7 3.6 271.7 30.5 0.0 3.1 3.9 192.9 26.1 1.7 0.9 96.2 12.2 33.0 11.4 118.6 9.0 31.6 3.6 2.8 8.7 2.9 1.0 0.5 0.5 105.9 194.7 3.0 2.1 104.6 57.2 10.8 2.7 0.3 0.0 1.9 5.6 0.9 0.8 12.7 10.5 1.0 2.6 0.1 111.0 118.4 ABCC4 "EST170205, MOAT-B, MOATB, MRP4" ENSG00000125257 "ATP binding cassette subfamily C member 4" O15439 13 95019835-95301475 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 41.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 51.3;granulocytes: 53.9;Microglial cells: 203.3" "Cancer enriched" "Detected in all" 8 "prostate cancer: 90.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "HEL: 245.7;HMC-1: 256.3;RPTEC TERT1: 69.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002476 Enhanced Supported "Nucleoli,Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Nucleoli, Golgi apparatus" "HPA002476: AB_1844434" "unprognostic (8.77e-2)" "unprognostic (1.94e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.89e-4)" "unprognostic (2.83e-2)" "unprognostic (1.23e-1)" "unprognostic (7.45e-3)" "unprognostic (2.40e-2)" "unprognostic (9.96e-2)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.55e-2)" "prognostic favorable (2.25e-10)" "unprognostic (7.44e-3)" "unprognostic (1.67e-1)" "unprognostic (5.55e-2)" "unprognostic (2.35e-2)" 2.2 1.3 2.5 6.1 2.3 4.1 6.9 2.5 2.5 4.9 7.2 9.2 4.9 3.4 18.8 2.0 10.2 6.1 2.0 2.3 5.4 18.0 1.3 7.6 3.9 4.3 3.7 3.7 3.3 22.5 1.4 2.1 4.6 41.1 8.5 0.9 1.5 5.5 5.3 2.9 5.4 6.3 4.9 4.1 5.2 4.7 3.2 3.9 7.7 1.7 6.3 15.4 1.8 5.1 18.5 31.7 5.3 9.4 9.5 12.3 1.3 14.4 14.3 12.6 10.9 43.8 13.2 10.2 9.3 19.5 9.0 24.0 7.9 7.1 15.8 30.7 12.1 245.7 8.8 8.8 19.2 28.6 256.3 9.4 3.2 9.1 18.5 17.9 16.4 11.3 25.8 0.4 17.1 5.9 5.4 4.6 6.2 22.3 7.9 7.7 14.3 26.9 69.3 40.4 12.5 9.3 4.8 1.2 10.1 5.9 0.0 15.1 27.0 13.3 8.6 11.2 17.3 0.1 0.0 4.0 25.4 16.0 6.6 0.2 0.5 0.2 1.3 0.6 1.1 1.4 1.0 1.5 1.8 1.6 0.6 1.5 0.3 1.9 2.3 0.3 1.5 1.3 2.5 2.3 2.5 2.5 2.3 5.4 4.3 3.7 4.6 4.9 3.2 5.1 4.6 9.6 32.7 28.4 5.8 4.2 7.0 7.3 4.0 0.1 0.6 0.6 4.5 8.6 9.1 23.9 22.9 0.1 2.0 2.7 0.0 6.9 3.8 4.2 11.3 19.8 0.0 51.3 13.6 3.1 0.4 5.7 6.1 6.0 53.9 9.5 2.9 0.6 4.5 0.0 10.3 4.0 0.0 2.5 8.1 2.0 6.8 10.7 1.8 203.3 13.5 0.5 4.1 16.1 2.5 2.9 8.3 1.9 8.3 27.1 0.5 26.4 4.7 0.8 0.0 8.2 3.1 0.9 8.3 3.4 7.5 0.3 6.4 17.3 9.2 4.5 ABCC6 "ARA, EST349056, MLP1, MRP6, PXE, URG7" ENSG00000091262 "ATP binding cassette subfamily C member 6" O95255 16 16149565-16223522 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 134.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 31.5;Distal tubular cells: 45.0;Hepatocytes: 77.9;Proximal enterocytes: 33.7;Proximal tubular cells: 151.1" "Group enriched" "Detected in many" 5 "liver cancer: 16.7;renal cancer: 5.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 7 "monocytes: 3.4" "Cell line enriched" "Detected in some" 8 "Hep G2: 68.4" "Not detected" "Not detected" HPA038105 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" Nucleoplasm "HPA038105: AB_2675835" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (5.98e-2)" "unprognostic (3.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.09e-1)" "prognostic favorable (3.82e-4)" "unprognostic (6.54e-3)" "unprognostic (3.64e-1)" "unprognostic (9.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.65e-1)" "unprognostic (1.12e-3)" "unprognostic (3.42e-1)" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.41e-1)" 5.6 3.6 0.7 0.3 0.7 0.7 3.8 0.7 1.1 1.0 0.8 5.7 13.2 0.3 0.6 0.3 1.5 2.9 2.6 0.7 0.7 27.4 134.2 7.4 0.0 0.8 0.9 1.0 17.2 2.1 0.9 0.2 0.8 2.9 2.8 0.3 12.7 1.0 4.6 0.4 7.9 0.3 0.7 0.7 6.4 0.4 0.8 0.0 5.6 0.1 0.0 0.4 0.7 0.7 0.0 1.5 0.7 0.0 0.0 0.8 1.8 0.0 0.4 1.0 1.6 7.1 2.3 0.0 0.8 0.0 0.2 0.0 0.7 0.1 0.6 0.0 0.7 1.8 0.2 68.4 0.4 0.0 0.0 2.7 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.6 0.0 0.0 0.0 0.0 2.3 0.0 0.1 1.0 0.0 0.8 0.1 0.3 8.4 5.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.4 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.7 0.7 0.7 1.1 0.7 0.7 0.8 0.9 0.8 0.7 0.8 0.7 0.3 28.9 31.5 2.9 1.9 0.1 0.5 3.2 0.0 1.0 4.3 3.6 3.3 18.6 8.7 9.2 0.0 0.0 0.0 13.7 45.0 2.2 0.5 4.8 1.0 0.8 3.0 2.7 1.0 7.9 0.0 1.7 13.3 1.0 1.3 1.9 1.8 77.9 1.0 0.0 1.1 10.9 0.0 3.5 0.0 0.7 1.5 1.8 1.8 3.7 3.1 1.5 0.0 1.0 0.4 2.2 8.1 5.7 0.3 2.0 33.7 151.1 25.4 0.6 0.0 0.3 1.2 0.4 0.3 0.2 0.9 0.0 1.4 1.8 11.9 0.7 ACKR3 "CMKOR1, CXCR7, GPR159, RDC1" ENSG00000144476 "Atypical chemokine receptor 3" P25106 2 236567787-236582354 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 39.6;Endothelial cells: 59.8;Fibroblasts: 171.2;Smooth muscle cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "NK-cells: 4.7;T-cells: 3.8" "Cell line enhanced" "Detected in many" "HeLa: 103.7;MCF7: 80.0;RT4: 312.3;SiHa: 97.0;U-2197: 328.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032003, HPA049718" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA032003: AB_2674107, HPA049718: AB_2680859" "unprognostic (1.65e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.50e-1)" "unprognostic (1.92e-3)" "unprognostic (2.10e-1)" "unprognostic (1.23e-1)" "unprognostic (7.34e-3)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (9.70e-3)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (2.01e-4)" "unprognostic (9.71e-2)" "unprognostic (8.57e-3)" "prognostic unfavorable (2.93e-4)" 116.2 5.2 13.0 14.3 13.5 3.5 70.4 13.1 15.6 29.2 18.3 38.7 11.8 17.3 10.5 25.0 33.7 30.8 68.5 13.7 18.9 11.3 28.3 26.3 10.5 22.3 16.0 15.9 37.9 5.0 24.4 123.3 14.4 20.1 24.7 1.7 21.4 16.8 35.4 38.1 34.1 24.2 14.3 56.0 27.9 14.6 14.5 6.4 58.1 37.9 5.6 107.0 38.2 13.6 0.0 0.1 6.3 0.0 10.5 0.2 44.9 2.6 1.4 2.3 4.6 0.5 0.1 0.0 5.1 0.2 16.9 68.0 0.2 24.0 0.4 0.1 0.0 0.1 103.7 0.2 0.1 0.2 0.1 3.2 61.0 0.3 0.0 15.4 11.2 0.3 1.2 0.1 0.0 80.0 0.2 0.2 11.0 0.0 0.7 0.1 7.6 0.8 0.0 312.3 0.4 0.1 97.0 0.5 0.0 23.9 0.0 0.3 0.0 0.8 23.3 328.5 0.1 1.4 0.0 0.1 1.2 6.6 0.5 0.0 0.1 0.0 2.5 0.2 3.8 0.3 1.3 3.2 0.1 0.6 1.1 1.5 0.0 4.7 0.4 0.0 2.0 0.5 13.0 13.5 13.1 15.6 13.7 18.9 22.3 16.0 14.4 14.3 14.5 13.6 33.2 9.6 4.8 20.5 1.1 22.0 0.2 39.6 1.2 1.7 0.2 1.0 9.1 0.0 24.8 0.0 0.0 0.1 0.7 1.0 0.0 0.2 0.9 13.5 24.2 59.8 0.0 0.0 0.7 10.4 0.8 171.2 1.1 24.8 6.3 6.3 33.5 2.5 0.8 0.0 2.3 0.1 6.1 4.1 10.1 0.4 1.5 6.9 1.8 12.2 0.8 0.1 1.0 1.0 0.1 1.3 5.3 1.2 0.5 0.5 3.3 0.9 5.8 0.1 0.0 35.7 37.1 0.2 0.3 1.1 15.9 0.3 1.5 1.1 0.2 2.6 ADA ADA1 ENSG00000196839 "Adenosine deaminase" P00813 20 44619522-44652233 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Nucleotide metabolism" Hydrolase "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 507.2;lymphoid tissue: 259.0" "Cell type enhanced" "Detected in many" "dendritic cells: 76.4;Extravillous trophoblasts: 128.2;NK-cells: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 168.5;NK-cell: 94.5;non-classical monocyte: 362.8;plasmacytoid DC: 218.6" "Group enriched" "Detected in all" 4 "dendritic cells: 218.6;monocytes: 362.8;NK-cells: 94.5" "Group enriched" "Detected in many" 5 "JURKAT: 570.9;MOLT-4: 1915.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001399, CAB004307, HPA023884" Enhanced Supported "Plasma membrane,Cytosol" No No 470000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 9: Intestine - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" Cytosol "CAB004307: AB_626634, HPA001399: AB_1078099, HPA023884: AB_1844573" "unprognostic (4.30e-2)" "unprognostic (6.89e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.23e-7)" "unprognostic (9.33e-2)" "unprognostic (9.07e-3)" "prognostic unfavorable (6.77e-5)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (3.66e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (2.94e-14)" "unprognostic (2.29e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-1)" "unprognostic (1.82e-1)" 16.6 6.3 6.9 18.5 8.2 20.2 10.9 6.8 9.4 7.3 5.6 5.7 507.2 3.8 1.7 9.0 5.6 9.2 17.8 6.9 7.0 3.3 4.4 6.2 33.4 7.2 8.2 2.1 5.3 1.5 1.3 4.6 7.2 4.3 3.6 0.3 4.7 2.8 5.3 6.0 17.9 5.7 6.1 17.5 46.0 2.4 8.7 259.0 5.8 6.4 26.4 9.3 5.4 8.8 14.0 37.7 19.2 13.2 35.6 48.7 30.5 13.7 7.8 13.2 9.3 17.5 14.8 38.4 15.8 17.9 24.7 2.2 13.2 55.1 7.3 2.9 17.2 7.8 6.6 13.5 15.0 6.3 20.3 234.3 23.2 5.1 9.0 12.6 50.3 570.9 20.4 30.7 6.0 33.1 1915.5 28.9 5.2 17.2 13.5 102.3 25.8 95.0 2.3 0.0 0.7 9.3 20.2 4.4 24.2 24.0 4.5 19.1 16.9 10.1 18.6 20.5 2.8 40.1 27.3 82.3 3.5 32.5 9.0 0.5 9.8 1.2 43.3 168.5 27.8 7.5 35.5 51.0 35.2 7.6 27.3 38.6 2.5 94.5 362.8 218.6 29.8 57.4 6.9 8.2 6.8 9.4 6.9 7.0 7.2 8.2 7.2 6.1 8.7 8.8 18.2 0.0 1.9 2.9 13.5 12.9 3.4 10.0 13.6 0.0 2.7 3.2 2.1 0.0 4.8 1.8 0.0 2.9 76.4 0.8 0.0 3.7 0.4 0.7 9.1 17.0 0.0 10.7 0.2 19.7 128.2 19.7 14.8 0.8 0.0 3.5 7.1 3.6 28.5 0.0 0.2 1.5 10.2 20.8 25.5 1.8 42.3 27.6 8.8 3.7 37.4 3.8 56.7 0.5 9.4 10.7 0.3 2.6 31.4 6.0 0.7 3.0 2.4 0.0 13.1 1.9 14.1 0.3 6.2 12.9 13.9 3.7 30.9 6.8 4.9 2.7 ADAM10 "CD156C, HsT18717, kuz, MADM" ENSG00000137845 "ADAM metallopeptidase domain 10" O14672 15 58588809-58749791 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 377.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 296.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001709, HPA050670" Approved Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 690000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "CAB001709: , HPA050670: " "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (5.04e-2)" "unprognostic (3.09e-1)" "unprognostic (2.70e-3)" "unprognostic (7.48e-2)" "prognostic unfavorable (8.46e-5)" "unprognostic (3.99e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (6.69e-2)" "unprognostic (2.57e-2)" "unprognostic (2.57e-3)" "unprognostic (9.14e-2)" "unprognostic (2.09e-2)" "unprognostic (1.60e-2)" 14.9 8.7 11.4 19.0 18.6 18.7 15.2 20.2 15.0 16.0 9.7 22.2 15.9 16.3 7.7 15.4 13.9 18.9 12.1 12.2 12.7 18.0 16.1 21.0 22.2 18.2 17.6 14.1 8.8 7.9 8.2 29.0 17.5 25.2 17.2 10.8 9.3 12.2 6.1 16.9 17.5 13.3 13.7 29.0 20.3 8.5 15.5 42.7 28.6 7.1 16.4 28.0 10.4 25.2 48.4 88.5 27.6 31.2 34.8 49.8 70.0 39.0 116.0 28.6 39.1 39.9 62.6 22.7 118.0 35.2 49.2 95.9 16.8 43.5 37.0 30.1 19.3 38.7 35.1 42.1 40.8 25.0 103.8 44.4 30.0 19.9 29.2 41.1 55.6 45.0 24.5 57.9 50.4 15.4 89.5 32.0 40.2 15.4 14.6 36.4 91.6 57.1 66.6 121.4 29.9 20.3 44.0 52.8 73.1 60.0 30.4 55.0 41.4 37.1 41.2 296.6 39.6 30.7 70.7 23.5 54.1 50.8 67.3 30.9 36.2 19.2 12.8 41.1 19.2 8.3 12.7 11.6 23.6 9.6 12.7 10.8 51.5 17.7 48.6 10.2 18.2 25.8 11.4 18.6 20.2 15.0 12.2 12.7 18.2 17.6 17.5 13.7 15.5 25.2 60.1 83.3 50.8 83.2 37.9 26.6 30.7 33.3 33.0 22.7 61.6 30.9 40.0 30.0 46.7 80.9 27.1 35.6 69.4 79.0 1.9 56.0 21.2 39.5 56.4 72.5 36.1 20.8 106.1 31.8 57.8 36.1 53.0 74.0 30.3 31.5 71.4 36.2 63.8 45.4 96.2 43.6 36.7 90.1 28.9 19.4 18.0 77.9 46.2 147.1 69.0 30.6 44.3 75.9 377.6 48.9 48.1 17.0 51.0 89.1 45.1 23.7 41.2 33.4 13.1 34.4 42.8 20.3 17.8 39.5 22.3 26.5 51.3 34.1 39.5 83.9 ADAM12 "MCMPMltna, MLTN" ENSG00000148848 "ADAM metallopeptidase domain 12" O43184 10 126012381-126388455 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 166.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 102.2;Extravillous trophoblasts: 400.8;Oligodendrocyte precursor cells: 99.0;Syncytiotrophoblasts: 129.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "MAIT T-cell: 6.1" "Lineage enriched" "Detected in single" 62 "T-cells: 6.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 154.2;hTEC/SVTERT24-B: 94.3;U-2197: 93.2;U-251 MG: 86.2;U-87 MG: 70.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030866, HPA030867, HPA030868" Enhanced Supported "Plasma membrane" "Secreted in female reproductive system" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA030866: AB_2673636, HPA030867: AB_10602428, HPA030868: AB_2673638" "unprognostic (3.35e-1)" "unprognostic (1.05e-3)" "unprognostic (3.52e-2)" "unprognostic (2.47e-2)" "unprognostic (3.34e-2)" "unprognostic (2.16e-1)" "unprognostic (2.91e-6)" "unprognostic (2.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.30e-2)" "unprognostic (2.53e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.39e-14)" "unprognostic (3.11e-3)" "unprognostic (9.06e-3)" "unprognostic (4.70e-3)" "unprognostic (3.47e-3)" 11.4 0.1 2.0 6.0 4.0 0.1 4.6 1.6 2.1 18.2 3.5 0.4 0.2 6.3 0.0 0.4 0.2 11.8 0.7 1.0 2.5 1.0 0.2 1.3 3.2 6.0 2.7 8.8 0.5 0.1 1.1 166.5 3.1 0.3 0.6 0.3 1.1 0.0 0.1 0.4 0.5 4.3 1.8 1.6 0.5 0.9 10.4 1.8 0.3 0.0 3.5 11.6 0.5 3.0 16.8 2.5 6.5 0.1 18.7 38.3 0.0 42.7 3.5 14.2 35.5 0.0 0.0 0.0 0.0 154.2 30.0 0.0 0.2 1.4 15.5 1.9 0.6 0.2 25.1 0.0 2.9 0.0 33.2 47.0 0.0 94.3 2.9 27.1 0.0 0.0 0.0 0.2 11.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 4.8 4.4 0.4 44.1 0.5 28.4 5.0 0.0 0.7 2.5 0.1 0.1 0.0 50.9 16.9 93.2 86.2 0.0 0.5 0.0 70.7 0.1 32.3 0.0 0.0 0.0 0.3 0.0 6.1 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 2.0 4.0 1.6 2.1 1.0 2.5 6.0 2.7 3.1 1.8 10.4 3.0 0.5 0.0 1.9 22.5 0.3 1.5 0.4 3.0 0.0 2.1 1.7 3.6 2.3 0.0 0.5 0.0 102.2 14.0 0.5 0.7 0.0 8.0 10.9 10.7 16.6 1.6 0.0 0.0 7.4 1.1 400.8 34.5 0.5 1.8 49.5 7.8 2.5 0.2 15.5 6.7 19.0 1.0 4.1 0.6 3.1 1.7 16.8 0.8 1.8 14.0 9.0 3.3 1.0 99.0 52.2 2.2 0.1 0.7 0.3 1.0 0.7 0.4 6.5 30.5 0.0 5.1 13.4 6.0 5.0 0.0 0.6 129.2 4.7 28.1 0.9 0.5 ADAM28 "ADAM23, eMDCII, MDC-Lm, MDC-Ls" ENSG00000042980 "ADAM metallopeptidase domain 28" Q9UKQ2 8 24294069-24359014 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 357.5;stomach 1: 110.3" "Cell type enhanced" "Detected in many" "B-cells: 240.9;Club cells: 62.9;Gastric mucus-secreting cells: 141.7;Microglial cells: 233.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 71.6;naive B-cell: 87.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "CAPAN-2: 27.8;OE19: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074034 Enhanced Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" Mitochondria "HPA074034: AB_2686654" "unprognostic (4.23e-2)" "unprognostic (1.01e-2)" "unprognostic (2.06e-2)" "prognostic favorable (3.17e-4)" "unprognostic (2.89e-1)" "unprognostic (2.55e-2)" "unprognostic (5.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.71e-1)" "unprognostic (1.35e-2)" "unprognostic (3.77e-3)" "unprognostic (7.77e-2)" "unprognostic (3.97e-3)" "unprognostic (1.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.62e-1)" 2.2 2.2 5.9 24.7 4.6 9.3 3.9 7.1 5.0 16.1 4.0 14.3 8.8 6.9 357.5 2.8 12.3 40.2 1.0 5.8 8.8 5.1 1.2 3.9 26.7 12.0 9.3 2.3 3.5 1.1 18.5 3.7 11.7 5.3 12.1 1.3 15.9 5.7 0.3 3.3 24.7 2.9 9.8 19.9 110.3 0.7 10.1 5.1 1.9 0.4 32.3 11.3 1.7 18.6 0.0 0.4 0.1 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 1.1 27.8 0.3 0.8 0.0 0.9 0.1 0.0 0.8 0.1 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.7 0.7 8.8 0.1 0.1 0.0 0.4 0.6 0.8 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.3 0.1 0.1 1.2 2.5 0.1 2.1 1.0 0.2 42.4 2.5 18.5 0.0 0.6 0.0 71.6 0.1 0.0 21.0 87.0 0.1 0.0 4.3 2.7 0.2 1.1 0.1 2.5 5.9 4.6 7.1 5.0 5.8 8.8 12.0 9.3 11.7 9.8 10.1 18.6 1.5 3.2 6.0 0.7 240.9 0.9 3.0 36.9 0.0 0.1 2.3 2.2 2.0 28.6 62.9 3.7 0.0 0.4 9.9 0.7 0.0 7.9 1.3 7.6 1.0 3.7 0.0 8.2 4.3 3.5 8.7 3.9 141.7 18.4 2.5 0.0 0.0 0.0 9.4 0.0 2.7 0.4 28.5 12.3 30.9 1.8 0.6 46.4 5.4 233.3 7.8 0.1 23.7 3.5 1.6 55.7 0.1 0.4 43.3 1.5 0.6 4.4 13.1 0.1 6.6 0.0 1.1 0.4 0.2 0.7 0.6 0.5 9.0 6.4 1.3 7.6 ADD2 ADDB ENSG00000075340 "Adducin 2" P35612 2 70607618-70768225 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 66.5;brain: 52.8" "Cell type enhanced" "Detected in many" "Early spermatids: 31.7;Erythroid cells: 74.1;Excitatory neurons: 70.1;Horizontal cells: 139.7;Inhibitory neurons: 51.8;Late spermatids: 62.4" "Group enriched" "Detected in many" 5 "glioma: 5.2;testis cancer: 11.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.2;non-classical monocyte: 2.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HAP1: 33.9;JURKAT: 33.1;K-562: 46.5;NTERA-2: 86.7;RPMI-8226: 41.7;SCLC-21H: 42.8;U-251 MG: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009796, HPA034509, HPA034510" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 18000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009796: AB_2223572, HPA034509: AB_2674201, HPA034510: AB_2674202" "unprognostic (3.58e-2)" "unprognostic (2.68e-4)" "unprognostic (3.83e-2)" "unprognostic (3.01e-4)" "unprognostic (1.94e-1)" "unprognostic (2.25e-3)" "unprognostic (1.35e-1)" "unprognostic (3.26e-1)" "unprognostic (3.49e-1)" "unprognostic (1.48e-1)" "unprognostic (1.20e-2)" "unprognostic (8.93e-2)" "unprognostic (4.47e-7)" "unprognostic (2.81e-4)" "unprognostic (1.77e-1)" "unprognostic (1.71e-3)" "unprognostic (1.31e-3)" 1.8 1.7 19.5 1.9 21.0 66.5 0.9 14.6 52.8 0.7 0.0 0.9 0.1 0.5 0.3 1.4 0.7 0.3 0.9 18.7 10.8 0.4 0.2 0.9 2.5 14.0 0.2 0.2 1.7 0.2 4.0 0.7 9.5 0.5 0.3 16.0 0.2 0.2 0.8 0.3 0.9 1.0 0.0 1.2 0.3 2.8 0.9 0.7 1.4 1.0 2.2 0.5 0.6 9.6 17.6 20.5 0.8 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.5 2.7 12.3 0.0 33.9 0.0 0.0 0.1 20.1 1.7 0.2 0.0 0.0 4.7 0.1 0.0 0.0 0.0 0.0 8.0 0.0 33.1 46.5 0.0 0.0 0.1 0.2 1.6 86.7 0.0 0.4 0.0 0.5 41.7 5.7 0.0 42.8 19.3 21.6 0.1 0.1 9.4 0.1 10.7 0.8 0.2 0.9 0.0 47.1 14.1 17.0 0.0 0.7 7.1 7.9 0.0 0.0 0.0 0.0 1.2 0.0 2.2 0.0 0.0 0.0 1.7 0.8 0.4 0.0 0.0 2.3 0.0 0.0 0.3 19.5 21.0 14.6 52.8 18.7 10.8 14.0 0.2 9.5 0.0 0.9 9.6 2.8 0.0 0.5 1.0 4.2 0.1 0.3 0.0 0.0 23.3 0.2 0.0 2.5 0.0 0.0 0.0 2.1 0.1 0.0 0.1 0.0 0.1 31.7 0.1 0.2 3.9 0.0 74.1 70.1 1.1 0.2 1.0 1.1 0.1 0.0 0.0 2.9 0.0 0.2 139.7 51.8 0.0 0.0 1.0 0.4 62.4 0.9 0.6 1.8 2.8 0.8 0.8 0.0 17.6 1.8 0.3 0.0 0.7 0.1 0.6 0.0 0.0 0.0 8.7 0.0 0.6 0.3 3.5 6.8 0.0 0.1 0.3 0.5 1.5 0.0 1.3 ADD3 ADDL ENSG00000148700 "Adducin 3" Q9UEY8 10 109996368-110135565 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 449.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.2;ASC TERT1: 292.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009797, HPA035696" Supported Supported "Plasma membrane" NA NA 260000 "Cluster 2: Granulocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB009797: AB_2223583, HPA035696: AB_2674740" "unprognostic (2.66e-1)" "unprognostic (2.63e-2)" "unprognostic (1.46e-3)" "unprognostic (1.64e-1)" "unprognostic (2.65e-2)" "unprognostic (1.75e-2)" "unprognostic (1.57e-3)" "unprognostic (6.42e-2)" "unprognostic (5.73e-2)" "unprognostic (2.37e-2)" "unprognostic (7.58e-2)" "unprognostic (9.12e-2)" "unprognostic (2.34e-3)" "unprognostic (1.36e-1)" "unprognostic (4.03e-1)" "unprognostic (3.68e-2)" "unprognostic (5.92e-2)" 57.7 21.7 105.6 38.8 97.2 37.5 89.4 88.6 129.3 57.6 65.9 58.2 71.9 24.9 62.4 39.0 47.6 72.0 59.9 113.3 108.1 102.7 27.8 38.4 70.9 107.3 94.8 46.4 67.9 18.8 25.3 36.6 102.0 32.7 66.0 99.4 59.1 31.8 9.6 33.6 85.4 23.9 105.2 40.0 63.7 51.5 95.6 87.4 87.7 25.6 65.4 42.3 40.1 122.4 29.2 6.0 41.7 19.8 313.2 292.1 17.7 41.2 110.9 25.4 49.9 60.3 90.6 89.9 45.2 63.9 26.4 10.0 37.3 27.1 39.5 9.0 46.5 8.8 28.5 45.9 35.5 30.5 66.0 142.5 12.9 63.3 2.6 96.4 37.8 109.9 23.5 48.7 46.7 0.8 32.3 31.0 25.8 69.2 15.3 27.7 58.2 4.8 65.7 14.2 6.1 67.9 27.6 8.9 66.5 62.2 10.7 11.4 9.5 16.0 42.0 33.5 9.1 68.9 31.5 82.7 47.8 16.2 27.7 139.5 29.6 98.0 68.8 26.5 55.7 51.4 72.9 59.1 24.8 42.9 83.2 67.6 47.1 73.4 32.6 16.3 73.3 94.9 105.6 97.2 88.6 129.3 113.3 108.1 107.3 94.8 102.0 105.2 95.6 122.4 67.3 22.4 52.9 449.2 110.6 55.7 35.9 77.4 38.7 26.8 56.0 34.4 128.2 74.4 85.5 36.8 60.5 55.6 112.7 125.2 60.7 27.2 51.4 70.3 76.0 77.7 102.4 32.6 83.4 61.1 12.1 182.4 100.9 56.0 26.0 18.8 126.7 12.2 25.7 116.1 141.1 71.6 48.8 88.5 41.1 25.7 226.5 66.3 58.7 70.3 65.3 339.0 151.4 236.8 279.6 59.8 167.1 251.3 68.4 38.4 135.2 162.2 151.9 121.7 65.7 27.6 36.2 122.7 62.1 53.2 50.6 22.3 111.5 30.9 166.7 98.6 ADGRB2 BAI2 ENSG00000121753 "Adhesion G protein-coupled receptor B2" O60241 1 31727117-31764893 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 61.4" "Cell type enhanced" "Detected in many" "Astrocytes: 20.9;Bipolar cells: 16.0;Excitatory neurons: 55.7;Inhibitory neurons: 13.8;Oligodendrocyte precursor cells: 20.6;Oligodendrocytes: 13.2" "Cancer enriched" "Detected in many" 4 "glioma: 20.5" "Region enhanced" "Detected in many" "hippocampal formation: 61.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 37.7;SH-SY5Y: 25.1;T-47d: 29.5;U-2 OS: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069175 Supported "Plasma membrane" NA NA 32000 "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA069175: " "prognostic favorable (6.46e-4)" "unprognostic (1.74e-1)" "unprognostic (7.98e-2)" "unprognostic (4.34e-2)" "unprognostic (1.90e-1)" "unprognostic (2.40e-1)" "unprognostic (8.17e-4)" "prognostic unfavorable (4.02e-5)" "unprognostic (2.31e-2)" "unprognostic (1.54e-2)" "unprognostic (1.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.80e-3)" "unprognostic (1.63e-1)" "unprognostic (1.23e-1)" "unprognostic (1.75e-3)" "unprognostic (7.98e-2)" 1.5 3.8 30.6 0.4 30.1 0.2 1.3 0.0 41.1 2.4 0.0 1.6 4.0 2.9 0.2 0.6 1.3 1.1 4.5 61.4 0.0 0.8 0.0 0.7 0.4 0.0 0.2 1.5 0.5 1.2 8.0 2.7 0.0 1.9 0.1 2.9 0.5 1.8 0.7 0.7 3.8 1.3 0.0 0.8 1.1 2.9 1.0 8.7 2.7 0.4 0.2 1.5 1.0 12.2 1.0 7.5 6.9 20.1 1.9 1.2 3.3 4.8 7.6 4.6 8.1 0.4 2.3 0.0 4.7 2.1 7.7 0.8 3.1 0.4 0.8 5.4 3.2 0.0 37.7 0.0 0.1 0.0 2.6 1.2 0.5 6.4 0.0 14.4 0.7 14.7 0.8 0.2 5.2 0.6 13.9 0.1 8.7 0.2 2.1 20.8 0.8 0.7 0.0 9.7 5.2 25.1 11.0 0.7 0.8 2.4 29.5 0.0 0.2 3.6 27.5 0.5 1.3 0.0 0.0 0.8 11.0 0.1 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.6 30.1 0.0 41.1 61.4 0.0 0.0 0.2 0.0 0.0 1.0 12.2 0.1 0.0 0.0 20.9 0.3 0.0 0.5 0.0 0.0 16.0 2.0 1.3 4.3 0.0 0.0 0.0 6.2 1.0 1.2 0.0 0.0 0.1 3.6 1.4 0.6 0.1 1.2 0.0 55.7 0.0 1.4 2.3 0.5 0.4 0.0 1.5 0.0 0.0 0.4 8.4 13.8 0.9 0.0 0.0 0.0 12.0 1.2 0.0 0.0 4.7 0.0 11.4 4.1 20.6 13.2 0.1 0.1 1.9 0.1 0.5 5.7 2.5 0.0 5.2 0.0 1.4 0.7 0.9 4.5 0.0 0.0 0.3 0.4 0.8 0.5 1.3 ADGRD1 "DKFZp434B1272, GPR133, PGR25" ENSG00000111452 "Adhesion G protein-coupled receptor D1" Q6QNK2 12 130953907-131141469 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 62.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 22.4;Alveolar cells type 2: 30.5;Cardiomyocytes: 47.0;Early spermatids: 16.2;Endometrial stromal cells: 50.2;Fibroblasts: 32.7;Late spermatids: 21.4;Leydig cells: 13.7;Microglial cells: 25.3;Peritubular cells: 15.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.0;intermediate monocyte: 2.3;myeloid DC: 1.1;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 6 "dendritic cells: 1.1;monocytes: 2.3" "Cell line enhanced" "Detected in some" "BJ: 4.1;fHDF/TERT166: 4.7;HeLa: 7.6;HHSteC: 4.9;HMC-1: 13.0;U-2 OS: 6.1" "Region enhanced" "Detected in some" "basal ganglia: 5.1" "Low region specificity" "Detected in all" "HPA042395, HPA076279" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane" "HPA042395: AB_10796906, HPA076279: " "unprognostic (3.21e-1)" "unprognostic (1.49e-4)" "unprognostic (1.32e-2)" "unprognostic (1.63e-1)" "unprognostic (4.40e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (9.27e-4)" "unprognostic (2.55e-3)" "unprognostic (1.63e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-2)" "unprognostic (3.98e-2)" "unprognostic (4.79e-5)" "unprognostic (1.31e-3)" "unprognostic (4.58e-1)" "unprognostic (2.15e-2)" "unprognostic (1.77e-3)" 26.4 1.9 1.9 1.3 2.0 0.3 10.3 1.2 2.5 20.6 1.0 10.6 1.9 15.4 7.3 6.9 17.7 12.9 62.4 1.4 3.2 3.4 10.3 35.6 0.4 2.0 2.6 17.9 12.0 0.3 6.3 25.7 2.2 15.3 1.8 0.8 2.9 1.0 7.3 7.0 12.1 7.1 2.0 2.3 20.7 7.5 3.6 0.4 11.2 8.5 1.0 40.3 16.3 1.7 0.0 0.7 0.0 2.0 0.0 0.0 0.1 4.1 0.0 0.0 0.4 0.0 0.0 0.3 0.0 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.6 0.0 4.9 0.0 13.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.8 0.0 0.1 0.2 2.1 0.5 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.4 6.1 1.5 0.1 0.1 1.7 0.8 0.1 0.0 0.0 0.0 2.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.8 1.9 2.0 1.2 2.5 1.4 3.2 2.0 2.6 2.2 2.0 3.6 1.7 2.0 22.4 30.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 47.0 0.0 5.0 1.8 0.0 1.3 0.0 0.0 0.0 0.0 16.2 1.3 50.2 3.4 0.0 0.0 1.1 0.4 0.6 32.7 0.5 1.0 1.3 0.3 1.8 3.6 2.3 0.0 1.4 0.0 0.0 1.5 0.0 21.4 13.7 1.5 0.0 25.3 3.5 0.0 0.0 0.0 0.1 0.3 0.0 15.8 0.0 0.0 0.0 0.1 2.2 0.7 6.6 2.2 3.5 4.3 6.5 0.1 0.0 1.0 0.6 0.2 0.1 0.3 ADGRG2 "EDDM6, GPR64, HE6, TM7LN2" ENSG00000173698 "Adhesion G protein-coupled receptor G2" Q8IZP9 X 18989307-19122637 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 1227.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 7.2;Endometrial stromal cells: 5.4;Fibroblasts: 5.3;Gastric mucus-secreting cells: 9.2;Oligodendrocyte precursor cells: 10.1;Oligodendrocytes: 7.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.0;BEWO: 7.3;HeLa: 5.9;NTERA-2: 6.4;RPMI-8226: 4.5;SH-SY5Y: 6.6;U-2197: 14.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA001478, HPA050029" Enhanced Approved "Plasma membrane,Cytosol" NA NA 22000000 "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA001478: AB_1078923, HPA050029: AB_2680996" "unprognostic (3.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.40e-1)" "unprognostic (2.55e-2)" "unprognostic (1.58e-1)" "unprognostic (4.43e-3)" "unprognostic (2.63e-4)" "unprognostic (2.66e-1)" "unprognostic (1.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-1)" "unprognostic (3.54e-7)" "unprognostic (6.37e-2)" "unprognostic (3.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.35e-1)" 3.9 0.3 0.1 0.9 0.1 0.0 2.0 0.0 1.1 1.0 0.0 0.5 0.5 1.0 1227.7 0.5 16.5 1.6 1.3 0.8 0.7 0.4 0.7 1.3 5.0 0.4 1.5 0.2 1.2 163.4 1.1 0.5 0.6 2.1 0.4 0.9 8.5 3.6 0.2 0.4 1.1 0.4 0.1 2.4 9.0 1.9 0.3 6.6 1.6 1.1 3.7 0.8 1.0 0.2 0.2 6.0 0.0 0.0 0.1 0.9 7.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.4 0.0 5.9 0.2 0.8 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 2.2 6.4 0.0 2.0 0.0 0.0 4.5 0.0 1.2 2.2 6.6 1.5 0.1 0.0 1.1 0.1 0.1 0.1 0.2 0.4 14.6 2.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.8 0.7 0.4 1.5 0.6 0.1 0.3 0.2 0.6 0.0 0.0 3.6 0.1 0.0 0.1 0.0 0.0 0.6 1.2 1.1 1.0 7.2 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.1 1.1 5.4 0.6 0.0 0.0 4.4 0.2 0.3 5.3 9.2 3.2 0.0 0.2 1.4 0.4 0.0 3.3 5.0 0.1 0.0 0.0 0.0 0.2 1.2 0.1 0.0 4.7 0.0 4.8 0.0 10.1 7.0 3.1 0.0 1.5 0.0 3.4 0.0 0.1 2.2 0.7 0.0 1.6 0.6 0.1 1.4 0.1 0.0 0.0 0.3 0.3 0.0 0.3 ADH1C ADH3 ENSG00000248144 "Alcohol dehydrogenase 1C (class I), gamma polypeptide" P00326 4 99336497-99352746 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "intestine: 598.1;liver: 2062.2;stomach 1: 570.6" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 699.4;Gastric mucus-secreting cells: 611.2;Hepatocytes: 440.6;Undifferentiated cells: 420.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 238.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.1;ASC TERT1: 3.6;HSkMC: 11.9;RPMI-8226: 2.1" "HPA047814, HPA060902" Supported Supported "Plasma membrane,Cytosol" NA NA 31000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (3.98e-2)" "unprognostic (9.88e-3)" "unprognostic (7.04e-2)" "unprognostic (1.90e-1)" "unprognostic (5.14e-1)" "unprognostic (1.57e-1)" "prognostic favorable (4.55e-4)" "prognostic favorable (2.99e-4)" "unprognostic (8.25e-2)" "unprognostic (8.89e-3)" "unprognostic (7.95e-2)" "unprognostic (2.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (9.37e-2)" 22.9 0.8 0.1 29.8 0.1 0.0 19.2 0.1 0.1 4.7 0.0 329.5 598.1 5.1 7.2 5.1 5.8 51.6 5.9 0.1 0.0 19.6 2062.2 2.9 0.6 0.1 0.1 4.0 16.7 0.1 1.6 0.1 0.1 9.4 191.9 0.0 19.3 6.2 23.9 0.7 190.7 16.3 0.1 0.7 570.6 0.8 0.1 0.5 2.9 31.1 0.5 5.9 3.6 0.2 0.0 2.1 0.0 0.0 1.4 3.6 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.2 1.1 0.3 11.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.8 0.2 0.0 0.1 0.1 0.8 2.1 0.8 0.0 0.3 1.1 0.5 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.3 0.1 0.1 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 2.1 3.2 7.3 0.7 1.3 0.0 4.0 0.0 25.0 0.0 0.1 0.3 1.0 64.3 24.8 29.5 0.0 0.0 0.1 108.4 0.0 159.5 2.3 1.3 0.8 1.2 21.6 29.5 0.3 699.4 0.0 21.1 611.2 1.3 0.0 0.0 13.2 440.6 0.0 0.0 0.2 86.3 0.0 13.2 0.0 1.0 10.5 0.8 0.0 0.0 2.0 0.0 0.0 0.5 0.1 66.3 120.8 0.0 0.6 3.1 59.4 1.4 43.7 0.0 0.0 1.3 2.0 0.0 0.7 10.6 0.0 0.0 1.8 1.6 420.5 3.6 ADORA1 RDC7 ENSG00000163485 "Adenosine A1 receptor" P30542 1 203090654-203167405 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.8;testis: 21.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 18.1;granulocytes: 22.3;Muller glia cells: 44.4;Oligodendrocyte precursor cells: 35.2;Oligodendrocytes: 31.5" "Cancer enhanced" "Detected in many" "glioma: 24.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 40.3;MCF7: 24.4;RH-30: 65.4;RPTEC TERT1: 31.7;SK-BR-3: 35.2;U-138 MG: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044383 Supported "Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA044383: AB_2678921" "unprognostic (3.93e-3)" "unprognostic (8.16e-2)" "unprognostic (6.16e-2)" "unprognostic (2.38e-3)" "unprognostic (2.25e-2)" "unprognostic (2.34e-1)" "unprognostic (4.64e-2)" "unprognostic (4.17e-2)" "unprognostic (3.04e-1)" "unprognostic (4.80e-3)" "unprognostic (1.42e-1)" "unprognostic (2.98e-1)" "unprognostic (2.96e-3)" "unprognostic (1.54e-1)" "unprognostic (1.27e-1)" "unprognostic (4.13e-2)" "unprognostic (5.76e-4)" 3.7 0.2 31.9 1.6 34.6 0.0 4.6 28.6 33.8 1.0 0.0 1.0 1.0 1.2 0.6 1.1 1.2 0.9 11.4 29.6 23.0 9.3 0.4 1.7 0.6 35.7 35.0 0.3 13.2 8.0 1.9 6.8 41.8 1.0 0.6 4.8 6.4 0.4 1.7 4.6 1.2 0.4 23.6 6.3 1.0 21.4 54.8 0.4 2.2 2.5 0.5 1.6 0.7 41.5 0.3 3.0 0.6 0.2 0.2 1.6 0.2 2.0 3.0 0.7 0.4 40.3 0.7 0.0 8.9 7.3 4.8 0.1 0.7 0.0 0.2 0.0 1.1 0.0 0.4 0.0 0.6 0.0 0.1 0.9 0.0 0.9 0.0 6.4 0.0 6.4 0.0 0.1 6.2 24.4 0.1 0.0 10.2 0.0 0.0 0.0 65.4 2.3 31.7 0.0 0.8 0.7 4.4 35.2 0.5 3.6 2.0 1.0 0.0 20.9 10.6 0.0 11.7 0.0 0.2 0.0 10.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.9 34.6 28.6 33.8 29.6 23.0 35.7 35.0 41.8 23.6 54.8 41.5 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 1.1 9.4 6.9 3.1 7.2 0.0 3.7 0.0 0.1 0.1 0.1 0.0 11.7 0.1 0.0 0.4 0.3 0.0 0.0 18.1 3.3 1.3 1.1 0.0 0.1 22.3 0.8 0.0 0.0 0.9 0.0 2.9 0.0 0.0 1.0 1.0 0.5 0.0 0.6 1.8 1.9 0.2 44.4 0.0 35.2 31.5 0.5 0.0 0.7 0.0 0.0 0.0 3.0 0.0 1.6 0.0 0.0 0.6 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 ADRA1B ENSG00000170214 "Adrenoceptor alpha 1B" P35368 5 159865080-159973012 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 36.9;liver: 11.4;lymphoid tissue: 11.6" "Group enriched" "Detected in some" 7 "Excitatory neurons: 41.5;Inhibitory neurons: 32.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 36.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 11.9;HaCaT: 5.8;TIME: 9.8;U-2 OS: 7.9;U-251 MG: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA074416 Supported "Plasma membrane" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA074416: AB_2686688" "unprognostic (4.93e-3)" "unprognostic (2.94e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (6.00e-5)" "prognostic unfavorable (6.98e-4)" "unprognostic (4.08e-3)" "unprognostic (1.67e-3)" "unprognostic (1.68e-1)" "unprognostic (6.12e-2)" "prognostic favorable (2.67e-4)" "unprognostic (2.28e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (1.40e-6)" "unprognostic (5.24e-4)" "unprognostic (2.54e-1)" "prognostic favorable (3.19e-5)" "unprognostic (1.59e-2)" 4.2 1.8 3.4 0.3 16.1 0.0 1.9 0.0 7.9 0.4 0.0 0.7 0.4 0.9 1.4 0.3 3.0 0.5 2.0 6.0 3.4 3.9 11.4 4.0 1.2 0.0 36.9 2.9 0.4 0.5 0.6 0.3 6.3 0.6 0.3 0.5 0.3 0.7 0.7 0.9 1.4 0.4 0.0 11.6 0.7 0.2 4.5 0.1 1.5 0.7 0.3 0.4 0.6 5.2 0.4 4.5 0.3 0.0 1.9 0.8 0.1 0.5 0.1 0.5 0.2 0.0 3.8 0.0 11.9 3.4 4.4 5.8 0.0 0.5 0.3 0.0 0.2 0.0 1.7 0.0 4.1 0.0 0.0 2.2 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.7 0.0 3.8 0.0 0.4 0.0 0.0 0.3 0.3 1.7 0.1 0.0 9.8 0.1 7.9 0.0 6.6 0.0 0.0 0.0 2.9 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 16.1 0.0 7.9 6.0 3.4 0.0 36.9 6.3 0.0 4.5 5.2 0.1 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.5 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 1.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AGER "RAGE, SCARJ1" ENSG00000204305 "Advanced glycosylation end-product specific receptor" Q15109 6 32180968-32184322 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "lung: 728.3" "Cell type enriched" "Detected in many" 22 "Alveolar cells type 1: 2394.2" "Cancer enhanced" "Detected in all" "lung cancer: 27.2;thyroid cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.5;JURKAT: 3.0;RPTEC TERT1: 2.2;U-266/70: 2.4;U-266/84: 2.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB011682, HPA064436, HPA069474" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cell Junctions" "Secreted in other tissues" NA NA 5360000 100000 "Cluster 19: Lung - Lung function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane, Cell Junctions" "Nucleoli fibrillar center" "CAB011682: AB_2258049, HPA064436: AB_2685264, HPA069474: " "unprognostic (9.37e-2)" "unprognostic (3.70e-1)" "unprognostic (2.37e-2)" "unprognostic (1.14e-1)" "unprognostic (4.55e-2)" "unprognostic (1.59e-3)" "unprognostic (4.36e-2)" "unprognostic (1.00e-1)" "unprognostic (4.38e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.41e-4)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.01e-7)" "unprognostic (3.57e-1)" "unprognostic (3.70e-2)" "unprognostic (4.44e-2)" "prognostic favorable (2.74e-6)" 2.2 1.7 0.1 1.1 0.1 0.5 1.6 0.1 0.4 4.4 0.2 3.9 0.6 2.5 1.9 2.1 4.5 0.1 2.7 0.2 0.1 6.4 2.7 728.3 0.6 0.2 0.1 4.8 1.7 0.0 5.0 0.4 0.2 4.9 0.8 0.4 1.6 0.0 1.0 2.0 3.2 0.1 0.1 7.0 2.0 2.2 0.2 0.8 39.2 0.1 0.5 2.9 3.2 0.3 0.1 0.0 0.0 0.3 0.1 0.9 1.5 0.0 0.1 0.0 0.1 0.0 0.2 0.1 1.0 0.2 0.0 1.0 0.1 0.3 0.2 0.2 2.5 0.7 0.0 0.0 0.0 0.3 1.1 0.0 0.1 0.0 0.1 0.2 0.1 3.0 0.0 0.3 0.1 1.3 0.1 0.9 0.0 0.1 0.0 0.0 0.1 0.1 2.2 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.5 0.0 0.1 0.0 0.6 0.8 0.1 2.4 2.0 0.9 1.1 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.3 5.4 2394.2 107.9 5.9 4.9 0.9 1.5 2.0 2.8 5.1 1.5 2.9 3.0 4.3 20.9 1.8 0.0 1.1 2.7 1.1 0.0 1.5 0.4 1.1 2.6 4.1 0.0 4.4 0.5 1.0 0.9 3.0 1.5 1.9 17.7 3.1 2.9 2.0 1.3 6.7 0.6 1.3 0.0 5.3 6.5 1.2 1.8 5.3 1.8 4.7 4.8 4.6 2.1 2.5 1.3 1.1 2.7 1.2 3.3 2.6 0.8 0.3 5.6 3.4 6.6 1.2 2.6 0.1 1.2 1.6 1.8 2.2 6.2 1.7 1.2 0.9 AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 224.5;intestine: 614.8;stomach 1: 432.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 193.0;Distal enterocytes: 201.0;Gastric mucus-secreting cells: 542.3;Proximal enterocytes: 327.1" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 104 "A549: 2959.1;Hep G2: 835.6;OE19: 3141.0" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" NA NA 67000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" 0.9 5.5 0.1 7.9 0.0 0.2 0.4 0.3 0.1 73.9 0.0 73.4 614.8 0.5 0.1 224.5 0.9 176.1 0.2 0.1 0.1 12.2 40.0 0.4 0.3 0.0 0.0 0.2 0.7 0.0 4.8 0.1 0.1 1.3 45.6 0.1 32.4 0.2 3.7 7.7 354.8 3.2 0.1 0.1 432.5 0.6 0.0 5.5 0.6 5.9 7.7 65.8 145.6 0.2 0.0 2959.1 0.0 0.0 0.7 2.3 9.0 0.3 1.1 0.2 0.0 5.9 0.9 0.0 1.1 1.6 4.6 6.2 0.0 4.0 0.2 0.1 0.0 0.0 1.9 835.6 0.7 0.0 0.6 0.1 13.8 0.7 0.0 4.0 0.5 0.0 0.0 0.0 0.6 5.4 0.1 1.3 0.5 3141.0 2.3 0.3 0.0 2.7 1.5 2.7 1.0 1.5 1.8 1.3 0.1 0.1 0.0 0.1 1.9 1.2 1.2 0.2 1.0 0.4 0.1 0.0 22.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 1.0 2.8 2.1 52.1 3.4 0.0 0.1 0.0 0.7 193.0 13.5 0.0 0.0 0.3 0.0 201.0 0.0 31.5 0.7 2.9 0.1 0.2 3.5 2.7 0.0 27.5 0.1 4.4 542.3 1.0 0.0 0.0 2.2 62.9 0.0 0.0 0.1 29.5 4.1 0.6 0.3 0.7 3.4 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 66.9 42.5 1.9 1.7 1.0 327.1 3.8 4.8 0.0 0.0 3.7 1.5 0.0 0.1 96.0 10.4 0.3 0.5 0.0 73.0 11.4 AKR1B15 ENSG00000227471 "Aldo-keto reductase family 1 member B15" C9JRZ8 7 134549110-134579875 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "breast: 166.7" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;Fibroblasts: 2.9;Late spermatids: 3.6;Skeletal myocytes: 12.5;Syncytiotrophoblasts: 10.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 15.8;HDLM-2: 12.8;Hep G2: 11.2;SK-BR-3: 5.1;U-87 MG: 6.7" "HPA020280, HPA073633" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 5: Breast - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (2.35e-1)" "unprognostic (3.85e-2)" "unprognostic (9.74e-3)" "unprognostic (2.74e-2)" "unprognostic (2.08e-1)" "prognostic favorable (8.36e-4)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.04e-2)" "unprognostic (2.39e-1)" "unprognostic (2.75e-1)" "unprognostic (2.14e-3)" "unprognostic (1.24e-1)" "unprognostic (1.22e-7)" "unprognostic (6.88e-2)" "unprognostic (4.29e-1)" "unprognostic (2.99e-3)" "prognostic unfavorable (1.90e-5)" 0.4 0.1 0.4 0.2 1.4 0.0 166.7 0.3 0.5 1.1 0.0 0.8 14.0 0.0 0.2 3.2 0.0 5.2 0.1 0.4 1.1 0.1 2.1 0.0 0.0 0.6 1.1 0.0 0.0 0.0 0.0 0.8 0.6 0.3 0.6 0.3 1.8 0.0 7.8 1.1 4.5 0.0 0.7 0.0 12.0 0.5 1.4 0.2 0.1 18.8 0.3 0.9 2.6 1.5 0.1 15.8 0.1 0.0 0.6 0.5 0.9 0.0 0.4 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.7 0.1 0.0 0.1 0.0 12.8 0.0 0.1 0.2 11.2 0.0 0.2 0.5 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.5 0.0 0.0 0.2 0.2 3.1 0.4 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.6 5.1 0.0 0.1 0.0 0.3 0.0 0.1 0.7 0.3 0.0 0.2 0.2 0.2 6.7 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.3 0.5 0.4 1.1 0.6 1.1 0.6 0.7 1.4 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.9 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 12.5 0.1 0.0 0.7 0.0 0.3 10.4 0.1 0.0 0.0 0.1 ALK CD246 ENSG00000171094 "ALK receptor tyrosine kinase" Q9UM73 2 29192774-29921586 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 10.9" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 274.2;Oligodendrocyte precursor cells: 433.8" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SH-SY5Y: 31.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010694 Approved Supported "Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA010694: AB_1078133" "unprognostic (4.96e-2)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "unprognostic (4.56e-7)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (9.07e-3)" "unprognostic (6.29e-3)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (2.67e-4)" "unprognostic (3.70e-2)" "unprognostic (2.06e-2)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" 0.3 0.6 2.2 0.2 2.4 0.0 0.1 0.7 2.8 0.1 0.8 0.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.5 3.9 0.0 0.0 0.1 0.0 4.4 6.8 0.0 0.0 0.0 1.3 0.0 10.9 0.0 0.2 0.7 0.1 0.1 0.0 0.1 0.3 0.1 2.9 0.0 0.1 1.2 2.7 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 4.3 0.0 0.0 0.1 0.4 31.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 0.7 2.8 1.5 3.9 4.4 6.8 10.9 2.9 2.7 2.1 0.0 0.0 0.0 66.6 0.0 0.0 0.0 0.0 0.0 1.9 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.1 0.5 0.1 0.2 0.0 0.0 12.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 274.2 0.0 0.0 0.0 0.0 41.2 0.0 0.5 0.0 7.5 0.0 0.6 0.0 433.8 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 ALOX15B 15-LOX-2 ENSG00000179593 "Arachidonate 15-lipoxygenase type B" O15296 17 8039034-8049134 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 111.7;prostate: 73.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 75.8;Basal respiratory cells: 22.0;Kupffer cells: 42.2;monocytes: 87.9;Prostatic glandular cells: 25.6;Squamous epithelial cells: 44.4" "Cancer enriched" "Detected in all" 5 "prostate cancer: 91.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "classical monocyte: 3.9;myeloid DC: 4.3" "Group enriched" "Detected in many" 8 "dendritic cells: 4.3;monocytes: 3.9" "Cell line enhanced" "Detected in some" "HHSteC: 7.7;HSkMC: 16.6;hTCEpi: 35.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010562 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Cytosol" "HPA010562: AB_2668305" "unprognostic (1.76e-2)" "unprognostic (6.47e-2)" "unprognostic (2.56e-1)" "unprognostic (2.28e-3)" "unprognostic (1.67e-2)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-2)" "unprognostic (4.59e-1)" "unprognostic (1.59e-2)" "unprognostic (9.37e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.49e-2)" 2.2 1.7 0.7 1.3 0.7 0.4 111.7 0.6 2.5 12.0 0.5 2.3 0.1 1.1 0.9 39.1 1.6 0.7 0.7 0.7 0.8 0.5 0.4 24.5 2.9 1.8 0.9 0.7 1.4 0.2 0.5 1.2 1.6 73.1 0.3 0.3 3.7 0.1 0.3 36.9 3.7 0.1 0.9 3.8 4.4 0.5 0.9 0.7 1.9 0.1 7.6 1.7 33.4 1.9 0.1 0.0 0.0 0.1 0.5 0.7 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 16.6 35.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.9 0.7 0.7 0.6 2.5 0.7 0.8 1.8 0.9 1.6 0.9 0.9 1.9 1.4 0.0 75.8 0.0 0.3 3.1 0.6 22.0 7.4 0.0 19.8 12.3 0.3 1.5 8.2 0.0 0.0 0.2 0.2 0.2 0.0 0.1 1.3 0.0 0.8 0.4 0.0 0.0 0.2 0.4 0.0 0.2 0.0 0.2 1.3 0.0 0.7 0.3 4.2 0.0 0.0 0.0 2.0 42.2 1.1 0.8 0.0 15.4 5.4 0.0 87.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 25.6 0.0 0.0 2.2 0.0 0.0 0.1 1.3 0.6 0.8 44.4 1.1 0.8 0.0 0.0 0.0 2.2 AMER1 "FAM123B, FLJ39827, RP11-403E24.2, WTX" ENSG00000184675 "APC membrane recruitment protein 1" Q5JTC6 X 64185117-64205708 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 15.3" "Cell type enhanced" "Detected in many" "Sertoli cells: 6.6;Theca cells: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065214, HPA065265" Approved Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "Nuclear bodies" "Vesicles, Plasma membrane" "HPA065214: AB_2685435, HPA065265: AB_2685450" "unprognostic (1.56e-2)" "unprognostic (8.85e-2)" "unprognostic (6.86e-2)" "unprognostic (2.74e-1)" "unprognostic (2.12e-2)" "unprognostic (1.86e-1)" "unprognostic (3.57e-2)" "unprognostic (1.48e-1)" "unprognostic (8.02e-2)" "unprognostic (1.75e-1)" "unprognostic (6.31e-2)" "unprognostic (3.43e-1)" "unprognostic (4.69e-4)" "unprognostic (1.26e-1)" "unprognostic (1.13e-1)" "unprognostic (6.19e-2)" "unprognostic (2.89e-1)" 1.1 1.4 1.6 1.3 1.5 1.2 1.3 1.8 1.6 1.9 0.1 1.5 1.5 1.9 4.0 2.8 2.2 1.0 1.3 1.0 1.6 1.8 2.1 1.2 1.2 1.5 1.4 6.3 2.0 1.6 0.7 0.8 1.5 1.7 1.3 1.3 2.2 2.2 4.1 2.2 1.3 2.8 0.7 1.3 1.6 0.4 1.9 1.6 1.4 15.3 1.6 1.3 1.3 1.0 3.1 2.2 5.8 4.6 2.2 2.1 4.7 1.4 1.2 2.1 1.3 7.3 1.1 5.9 1.8 3.0 1.6 4.3 12.5 4.1 2.0 2.5 2.5 3.7 4.9 4.9 1.6 7.7 0.9 3.0 5.3 1.6 3.2 1.7 1.2 4.6 5.6 5.9 1.1 3.7 5.2 4.0 15.6 4.0 4.4 11.7 9.4 4.3 0.9 1.0 2.6 3.9 3.7 5.0 1.9 4.8 1.6 2.1 0.8 2.5 5.8 6.7 1.9 3.0 2.2 4.4 1.2 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 1.5 1.8 1.6 1.0 1.6 1.5 1.4 1.5 0.7 1.9 1.0 0.9 0.0 0.0 1.0 1.5 2.2 0.6 0.9 2.8 5.0 1.7 1.5 2.6 4.3 0.3 0.0 2.1 1.1 3.4 1.1 0.0 1.2 0.1 3.3 2.6 1.5 1.2 0.8 0.8 1.6 0.8 1.8 3.6 2.0 0.0 3.9 1.4 2.6 0.4 0.0 1.3 1.0 0.0 1.0 0.3 0.2 2.5 0.5 1.8 1.0 1.2 0.2 0.0 1.0 0.6 0.7 0.5 4.1 2.4 1.2 0.8 0.8 0.0 1.0 6.6 2.3 4.4 0.0 0.2 3.6 2.6 0.7 0.9 6.4 1.6 0.7 AMER2 "FAM123A, FLJ25477" ENSG00000165566 "APC membrane recruitment protein 2" Q8N7J2 13 25161679-25172288 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 114.8" "Cell type enhanced" "Detected in some" "Astrocytes: 99.3;Bipolar cells: 105.5;Cone photoreceptor cells: 81.3;Horizontal cells: 153.1;Muller glia cells: 313.0;Oligodendrocytes: 337.1;Rod photoreceptor cells: 112.1" "Cancer enriched" "Detected in single" 24 "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 3.3;SCLC-21H: 2.3;SuSa: 2.3;U-266/70: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039458 Enhanced Supported "Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA039458: AB_10795677" "unprognostic (1.69e-2)" "unprognostic (4.13e-2)" "unprognostic (7.43e-3)" "unprognostic (2.32e-1)" "unprognostic (3.00e-3)" "unprognostic (5.00e-3)" "unprognostic (7.28e-2)" "unprognostic (2.34e-2)" "unprognostic (5.90e-4)" "unprognostic (1.60e-2)" "unprognostic (1.20e-2)" "unprognostic (1.52e-1)" "unprognostic (1.13e-1)" "unprognostic (1.34e-1)" 0.2 0.1 36.7 0.0 72.0 0.0 0.0 37.9 52.2 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 41.2 37.7 0.0 0.0 0.1 0.0 58.9 49.1 0.0 0.0 0.0 4.1 0.0 41.9 0.1 0.0 25.8 0.0 0.2 0.2 0.1 0.0 0.0 36.8 0.0 0.0 1.2 49.1 0.0 0.0 0.0 0.0 0.0 0.0 114.8 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.7 72.0 37.9 52.2 41.2 37.7 58.9 49.1 41.9 36.8 49.1 114.8 0.0 0.0 0.0 99.3 0.1 0.1 0.0 0.0 0.0 105.5 0.1 0.1 1.1 0.0 0.0 0.0 81.3 0.1 0.0 0.1 0.0 0.0 2.3 0.0 0.6 0.8 0.0 0.0 21.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 153.1 24.4 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.8 4.7 0.0 313.0 0.0 28.6 337.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 112.1 0.0 0.2 0.0 2.8 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 ANK2 "CFAP87, FAP87, LQT4" ENSG00000145362 "Ankyrin 2" Q01484 4 112818032-113384221 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 165.7;retina: 191.2;skeletal muscle: 171.7;tongue: 150.5" "Group enriched" "Detected in many" 4 "Astrocytes: 1101.2;Bipolar cells: 376.6;Cone photoreceptor cells: 479.6;Excitatory neurons: 1282.0;Horizontal cells: 1431.8;Inhibitory neurons: 1060.7;Oligodendrocyte precursor cells: 497.1;Oligodendrocytes: 1351.0;Rod photoreceptor cells: 484.4" "Cancer enhanced" "Detected in many" "glioma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 29.2;ASC TERT1: 32.2;RH-30: 49.6;SH-SY5Y: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008007, CAB015178, HPA035970" Enhanced Approved Supported "Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB015178: AB_2242828, HPA008007: AB_2667965, HPA035970: AB_2674893" "unprognostic (8.33e-2)" "unprognostic (9.47e-2)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.73e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.79e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.41e-6)" "unprognostic (1.18e-2)" "unprognostic (3.16e-1)" "unprognostic (1.51e-3)" "unprognostic (2.04e-3)" 31.0 13.6 94.9 11.2 109.0 0.1 18.3 63.1 165.7 31.6 0.0 30.1 8.5 15.8 5.9 12.9 9.6 22.5 119.5 103.9 77.5 110.1 2.4 7.2 9.2 130.2 61.1 27.3 3.2 1.2 19.3 2.1 119.5 7.8 11.4 191.2 6.7 13.3 171.7 8.7 12.7 24.9 51.9 28.3 8.3 9.4 84.8 4.4 9.6 150.5 7.2 9.5 12.3 116.2 0.1 2.9 18.7 5.2 29.2 32.2 0.1 1.5 3.4 0.9 2.6 4.2 0.0 6.9 2.1 5.9 4.1 0.1 11.0 0.6 1.0 2.3 7.3 4.0 0.0 2.9 1.7 1.9 1.2 15.2 3.0 1.2 6.0 3.9 0.0 0.4 0.0 9.3 5.8 0.3 0.2 0.1 9.4 0.1 2.0 0.7 49.6 0.0 0.2 0.0 13.6 24.1 0.2 0.7 8.1 11.7 0.1 1.1 0.0 4.7 2.2 0.4 3.0 6.8 1.8 0.9 20.1 0.6 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 109.0 63.1 165.7 103.9 77.5 130.2 61.1 119.5 51.9 84.8 116.2 6.9 0.0 3.9 1101.2 1.1 10.5 0.0 0.0 1.8 376.6 0.2 0.6 188.5 0.0 1.3 20.2 479.6 0.1 0.0 0.0 15.6 0.0 111.2 36.4 6.0 6.4 66.0 0.0 1282.0 1.6 0.1 79.0 2.0 7.2 1.3 81.8 0.0 0.4 1.0 1431.8 1060.7 0.4 8.2 0.0 19.7 49.8 36.4 2.9 17.8 90.9 0.6 44.5 0.0 497.1 1351.0 0.1 5.0 30.1 0.9 0.4 0.1 127.9 0.8 484.4 6.6 24.3 26.5 2.3 1.5 0.8 9.5 0.0 1.9 2.6 0.3 0.2 ANK3 ENSG00000151150 "Ankyrin 3" Q12955 10 60026298-60733490 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism spectrum disorder, Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 490.2;Excitatory neurons: 859.2;Inhibitory neurons: 881.3;Oligodendrocyte precursor cells: 592.6;Oligodendrocytes: 1579.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 50.3;SK-BR-3: 49.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013249, CAB015179, HPA038455" Enhanced Supported "Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB013249: AB_2533145, CAB015179: AB_633909, HPA038455: AB_2676020" "unprognostic (1.91e-1)" "unprognostic (5.33e-3)" "unprognostic (6.76e-3)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (3.70e-3)" "unprognostic (3.47e-1)" "unprognostic (1.62e-1)" "unprognostic (1.89e-1)" "unprognostic (1.21e-2)" "unprognostic (3.83e-1)" "unprognostic (2.28e-2)" "prognostic favorable (8.88e-16)" "unprognostic (5.75e-2)" "unprognostic (2.59e-1)" "unprognostic (1.00e-1)" "unprognostic (2.83e-2)" 6.3 6.7 45.5 6.5 86.5 2.1 21.5 144.9 82.3 12.0 0.0 26.0 39.3 23.0 125.2 16.9 19.1 21.5 81.1 60.8 86.1 95.4 16.6 24.6 6.1 82.7 61.3 11.6 11.2 131.8 14.5 15.6 97.0 20.0 20.9 123.2 42.6 40.5 80.5 39.9 27.2 13.2 21.2 10.8 15.5 8.0 87.3 9.1 41.6 94.1 7.4 10.8 14.1 114.4 8.7 4.9 30.3 0.4 0.0 1.8 23.3 0.6 0.4 0.1 0.6 22.2 16.6 0.5 9.8 0.6 0.9 12.1 16.4 14.9 0.5 0.5 11.0 0.2 9.7 0.1 6.2 0.1 0.4 14.6 9.3 7.8 0.4 26.1 3.6 0.0 4.3 20.6 6.9 29.0 0.2 1.0 13.8 23.3 26.6 0.1 21.7 4.3 5.4 50.3 15.6 2.8 0.6 49.4 0.0 33.6 28.7 0.1 10.0 0.9 2.9 13.3 1.5 0.9 0.2 0.2 5.5 0.2 18.9 1.6 0.2 0.5 2.7 0.2 2.4 4.1 4.6 1.5 0.1 1.1 5.0 1.2 0.7 1.5 0.3 2.5 0.8 1.0 45.5 86.5 144.9 82.3 60.8 86.1 82.7 61.3 97.0 21.2 87.3 114.4 0.9 44.8 174.3 20.2 14.5 19.1 21.9 17.8 38.7 490.2 26.8 20.6 189.3 12.8 42.5 53.3 225.2 38.8 3.4 62.9 19.6 10.6 28.3 139.8 26.2 3.9 30.6 0.0 859.2 8.6 9.9 13.2 15.8 153.3 12.6 66.9 7.9 0.5 4.7 43.7 881.3 12.1 14.2 4.8 1.4 11.5 28.0 3.3 8.8 23.4 4.4 41.4 0.0 592.6 1579.5 4.8 41.8 5.7 3.4 12.2 62.5 51.3 66.7 216.6 0.0 30.2 11.7 1.1 2.3 35.9 18.2 25.0 18.5 4.5 17.8 18.4 ANKIB1 "DKFZP434A0225, KIAA1386" ENSG00000001629 "Ankyrin repeat and IBR domain containing 1" Q9P2G1 7 92245974-92401383 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.5" "Cell type enhanced" "Detected in all" "Excitatory neurons: 182.5;Inhibitory neurons: 218.0;Oligodendrocyte precursor cells: 176.5;Oligodendrocytes: 590.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019358, HPA021780" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA019358: AB_1844831, HPA021780: AB_2670819" "unprognostic (1.77e-1)" "unprognostic (5.96e-3)" "unprognostic (1.23e-1)" "unprognostic (4.97e-3)" "unprognostic (2.75e-1)" "unprognostic (7.67e-2)" "unprognostic (4.88e-3)" "unprognostic (2.14e-1)" "unprognostic (4.24e-2)" "unprognostic (1.87e-2)" "unprognostic (1.52e-3)" "unprognostic (1.48e-1)" "unprognostic (1.06e-3)" "unprognostic (4.05e-2)" "unprognostic (3.00e-1)" "unprognostic (3.00e-2)" "unprognostic (3.20e-1)" 12.6 10.6 28.4 10.0 56.8 6.9 12.3 21.2 42.0 12.6 0.0 12.9 11.1 12.0 15.9 11.8 9.8 14.9 10.2 19.0 54.6 25.6 10.6 11.0 13.2 32.9 32.4 12.6 12.2 23.9 7.5 12.7 34.5 10.0 12.8 9.9 13.9 11.2 7.7 14.4 12.0 13.6 14.0 12.4 11.7 20.8 36.3 14.5 17.2 9.9 11.7 13.2 9.0 85.5 35.7 20.9 18.7 27.3 32.0 34.9 19.2 27.1 30.0 25.4 34.0 15.8 52.0 20.0 23.4 39.7 66.8 16.5 16.5 28.1 38.0 35.1 14.0 13.1 23.7 12.1 22.0 18.8 26.5 23.1 22.8 31.0 38.2 34.6 28.7 17.4 16.9 41.8 30.0 27.5 39.6 17.0 19.6 23.9 23.7 14.6 22.8 21.9 26.6 30.7 25.5 29.4 39.2 41.8 22.4 34.8 17.5 10.2 26.2 48.5 40.2 55.3 27.8 26.7 52.3 25.4 27.7 21.9 56.2 1.4 0.4 1.2 0.9 0.7 0.7 1.7 0.9 1.3 0.4 2.0 0.7 1.0 0.2 1.2 0.6 1.6 1.9 0.4 28.4 56.8 21.2 42.0 19.0 54.6 32.9 32.4 34.5 14.0 36.3 85.5 24.1 25.6 30.4 97.6 21.8 18.6 17.5 16.4 13.1 20.8 25.6 20.2 33.4 24.3 22.3 27.6 18.8 13.4 27.8 20.7 1.9 21.5 52.8 21.5 37.2 22.4 41.9 8.8 182.5 19.2 25.2 25.9 14.3 27.0 26.6 47.4 27.8 15.1 13.5 30.3 218.0 24.8 10.2 22.2 16.1 61.1 33.2 20.4 17.8 87.1 20.6 27.3 34.0 176.5 590.8 33.5 11.8 40.6 23.4 26.5 20.8 37.3 18.8 16.2 19.7 34.8 26.1 70.9 50.4 20.3 22.7 14.0 22.7 31.2 21.7 21.9 ANKRA2 ENSG00000164331 "Ankyrin repeat family A member 2" Q9H9E1 5 73552190-73565667 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003968, HPA065263" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA003968: , HPA065263: AB_2685449" "unprognostic (1.75e-1)" "unprognostic (5.78e-2)" "unprognostic (1.40e-1)" "unprognostic (1.86e-1)" "unprognostic (3.31e-1)" "unprognostic (3.89e-2)" "unprognostic (5.68e-2)" "unprognostic (6.19e-2)" "unprognostic (3.47e-2)" "unprognostic (1.09e-1)" "unprognostic (1.06e-2)" "unprognostic (1.79e-1)" "unprognostic (9.80e-3)" "unprognostic (3.36e-1)" "unprognostic (3.31e-1)" "unprognostic (6.65e-2)" "unprognostic (1.13e-3)" 7.8 11.3 4.6 5.7 5.1 14.0 10.1 5.7 5.4 9.4 5.2 8.9 9.6 12.4 13.1 7.5 11.4 9.7 8.2 4.2 5.1 5.9 10.8 7.0 9.9 5.0 4.9 14.1 8.3 8.0 7.5 10.0 5.3 12.4 10.4 9.9 10.9 8.4 7.6 9.1 9.6 8.3 5.1 8.8 10.0 6.7 5.2 10.0 14.3 6.6 8.1 7.4 7.7 6.2 6.6 4.5 6.6 7.5 12.3 19.3 20.6 9.0 13.2 7.6 11.0 1.4 9.4 6.2 7.0 8.8 7.3 4.5 3.1 15.4 10.9 11.9 5.5 5.4 3.6 6.5 9.6 3.1 9.3 19.8 21.0 9.1 9.2 13.6 8.7 6.7 5.3 9.9 8.6 3.8 5.6 8.5 3.9 2.5 3.7 3.5 7.1 8.7 5.6 8.2 9.0 6.9 6.9 5.3 11.0 10.2 8.2 5.0 11.2 3.0 3.4 4.9 6.3 19.7 15.1 5.3 7.5 5.1 8.8 19.9 5.1 11.2 7.6 4.5 9.3 9.9 8.9 10.7 4.6 8.0 13.3 12.4 8.4 7.3 7.8 5.3 11.5 6.8 4.6 5.1 5.7 5.4 4.2 5.1 5.0 4.9 5.3 5.1 5.2 6.2 10.7 3.2 11.5 10.4 23.5 15.8 30.1 29.8 26.2 26.2 20.7 15.9 8.9 31.5 22.7 18.4 10.4 26.3 27.1 16.0 27.4 14.1 1.3 18.1 11.0 12.8 24.1 21.5 10.0 16.6 22.2 13.8 10.7 13.4 19.0 18.8 15.7 23.8 10.5 23.5 12.9 22.6 36.7 18.5 6.7 2.2 32.6 11.1 12.4 16.9 15.1 16.2 17.5 21.1 22.3 16.9 20.0 29.0 14.6 25.7 21.5 18.0 21.4 21.2 26.3 11.3 17.8 25.6 15.9 16.0 12.4 48.8 20.4 16.3 17.0 36.8 ANKRD13A "ANKRD13, NY-REN-25" ENSG00000076513 "Ankyrin repeat domain 13A" Q8IZ07 12 109999186-110039763 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 160.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 205.4;HBF TERT88: 200.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039488, HPA043218" Enhanced Supported "Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA039488: AB_10673612, HPA043218: AB_2678367" "unprognostic (1.54e-1)" "unprognostic (3.94e-3)" "unprognostic (5.81e-1)" "unprognostic (1.62e-2)" "unprognostic (1.05e-1)" "prognostic favorable (7.70e-6)" "unprognostic (5.68e-2)" "unprognostic (1.31e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (6.77e-4)" "unprognostic (9.71e-3)" "unprognostic (1.67e-1)" "unprognostic (2.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.13e-2)" "unprognostic (1.08e-1)" "unprognostic (5.29e-2)" 13.2 10.9 6.3 36.5 10.0 36.0 16.4 8.8 8.1 14.1 6.1 21.8 14.3 11.9 6.6 31.7 12.3 22.9 10.7 7.1 7.4 17.6 15.3 26.9 54.0 8.4 8.7 16.3 12.3 17.4 4.6 24.4 9.0 17.9 22.4 8.7 27.5 24.6 6.9 22.6 17.6 24.4 7.5 32.8 17.1 60.9 8.4 27.9 28.2 8.7 66.7 25.9 13.2 15.0 163.7 7.3 16.9 15.6 25.4 25.1 20.8 160.9 150.5 149.8 79.3 21.2 10.3 107.8 12.4 205.4 18.7 19.0 21.7 24.0 200.3 122.3 19.2 39.9 15.6 17.4 22.2 46.8 46.2 21.9 24.9 63.8 36.5 37.3 23.0 24.9 31.6 17.2 66.5 5.8 41.3 19.5 9.3 11.7 34.1 35.8 47.3 42.7 21.2 20.7 34.7 16.5 29.6 57.0 19.5 11.4 26.0 38.5 29.2 111.6 20.0 62.2 87.4 36.8 23.3 144.1 54.3 31.7 16.5 1.5 1.2 5.6 0.5 2.5 1.5 2.0 1.3 0.6 1.5 1.2 0.7 1.0 3.5 0.9 1.1 1.0 0.6 0.7 6.3 10.0 8.8 8.1 7.1 7.4 8.4 8.7 9.0 7.5 8.4 15.0 15.7 48.1 32.5 13.4 75.5 29.3 18.7 11.0 15.4 24.4 23.1 16.9 13.0 28.6 30.5 57.0 14.6 16.9 31.2 30.3 21.5 29.2 104.7 22.0 12.3 14.9 18.7 19.4 15.9 17.6 21.0 15.5 16.3 29.5 13.3 18.5 15.7 17.3 15.4 25.2 26.9 9.4 4.1 37.1 26.9 160.4 11.8 33.7 14.2 16.9 34.2 9.7 21.6 17.6 46.0 20.8 12.5 21.8 33.0 16.2 16.0 9.8 37.6 14.2 32.9 50.3 18.0 71.1 15.0 23.9 37.8 37.6 31.8 16.9 17.0 25.7 ANO1 "DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A" ENSG00000131620 "Anoctamin 1" Q5XXA6 11 70078302-70189528 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Developmental protein, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 181.7;salivary gland: 180.5;seminal vesicle: 209.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 70.2;Early spermatids: 54.9;Hepatocytes: 141.3;Late spermatids: 75.1;Sertoli cells: 46.0;Smooth muscle cells: 52.5;Suprabasal keratinocytes: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 140.2;CAPAN-2: 207.9;HaCaT: 254.0;OE19: 182.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 6.6" "HPA032148, HPA057356" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" Nucleoplasm "HPA032148: AB_2674180, HPA057356: AB_2732610" "unprognostic (2.73e-1)" "unprognostic (7.91e-2)" "unprognostic (3.66e-2)" "prognostic favorable (4.58e-6)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.28e-5)" "unprognostic (1.16e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (2.13e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.21e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.81e-1)" 16.3 2.2 0.3 3.6 1.6 0.1 86.8 0.8 1.3 46.7 0.1 14.3 3.6 40.0 181.7 12.7 59.1 54.4 21.9 0.5 0.1 6.4 108.5 16.1 3.4 1.0 0.2 2.9 9.1 48.0 4.4 5.2 1.1 17.1 11.0 0.9 180.5 209.2 12.7 97.4 4.6 30.1 0.2 1.2 48.3 10.4 0.1 1.5 35.4 33.0 4.0 6.7 12.8 0.5 140.2 5.3 0.3 4.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 207.9 0.0 2.5 0.0 0.3 254.0 0.0 0.7 0.0 0.4 0.2 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.4 0.2 0.0 0.6 0.0 0.0 0.1 0.0 1.0 0.5 0.3 1.1 182.2 19.6 0.3 0.0 0.7 0.0 0.2 7.3 0.2 0.1 43.1 0.8 1.4 16.2 0.5 0.5 0.3 1.1 0.0 3.5 0.1 0.3 0.2 0.2 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.8 1.3 0.5 0.1 1.0 0.2 1.1 0.2 0.1 0.5 7.2 0.0 0.0 0.7 0.4 17.7 21.5 4.2 0.0 0.0 30.5 70.2 3.5 17.2 2.0 0.0 0.0 1.3 0.2 0.4 0.0 4.1 54.9 10.0 27.5 5.6 0.0 2.7 0.7 0.0 0.6 4.2 36.7 18.5 4.5 0.0 3.3 141.3 0.2 0.0 20.4 13.3 0.0 1.6 3.0 75.1 1.8 0.7 5.4 2.8 0.0 0.8 0.0 1.5 0.7 1.0 0.5 1.5 0.3 22.6 0.0 0.7 0.3 0.4 46.0 1.1 52.5 1.4 2.3 1.4 46.7 4.1 0.7 0.1 0.4 20.9 ANO10 "FLJ10375, MGC47890, SCAR10, TMEM16K" ENSG00000160746 "Anoctamin 10" Q9NW15 3 43354859-43691594 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 123.3;Excitatory neurons: 77.4;Inhibitory neurons: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016624, HPA051569" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA016624: , HPA051569: AB_2681537" "unprognostic (1.51e-3)" "unprognostic (1.38e-2)" "prognostic favorable (6.70e-4)" "prognostic favorable (1.11e-4)" "unprognostic (4.23e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (7.99e-3)" "unprognostic (1.03e-2)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "prognostic favorable (6.41e-6)" "unprognostic (9.83e-3)" "unprognostic (1.22e-1)" "unprognostic (5.19e-3)" "unprognostic (5.71e-2)" 26.6 14.1 17.6 15.1 18.6 33.0 21.8 23.9 20.9 22.3 18.4 39.4 61.1 21.6 13.6 25.3 13.9 19.4 12.7 18.1 21.1 29.9 14.1 16.9 7.6 22.7 22.9 13.9 15.2 23.7 13.9 18.1 23.2 14.2 33.7 10.1 28.6 20.2 15.5 32.0 54.7 28.0 19.6 9.1 13.5 13.0 19.8 7.1 24.5 11.6 9.7 18.1 21.5 24.1 30.6 23.6 26.1 27.4 101.1 53.5 31.2 87.7 141.1 42.0 54.4 16.2 27.5 3.1 27.4 114.8 43.1 16.3 20.6 47.0 52.6 33.6 14.2 39.4 28.7 17.7 43.9 7.2 31.1 50.5 36.3 53.6 71.8 79.4 100.3 18.7 30.8 24.9 95.2 20.8 7.8 5.2 31.3 23.7 28.6 6.3 18.7 10.2 85.5 31.4 6.4 19.4 34.4 27.0 19.8 45.3 59.5 14.5 84.7 66.2 24.4 70.2 40.7 15.7 22.9 1.1 60.2 14.6 44.2 7.4 19.0 1.4 6.7 11.1 3.8 2.7 4.6 4.5 13.1 2.5 3.9 6.0 32.8 9.7 12.7 2.3 5.4 7.0 17.6 18.6 23.9 20.9 18.1 21.1 22.7 22.9 23.2 19.6 19.8 24.1 24.3 6.4 3.2 70.2 4.1 5.6 5.8 6.9 8.0 8.0 18.2 8.4 5.2 8.6 13.2 14.7 0.0 14.4 3.7 38.5 123.3 21.6 2.9 11.8 23.6 17.8 9.6 11.8 77.4 17.8 19.5 10.6 10.2 31.2 2.5 6.8 23.6 10.7 11.6 10.1 97.9 23.8 10.2 9.6 5.3 5.2 5.6 9.1 14.2 69.3 9.2 17.1 5.2 71.4 46.4 11.7 22.1 10.1 2.6 4.4 58.4 19.0 4.0 3.6 6.6 19.1 15.7 17.1 23.6 8.7 6.1 17.1 5.8 6.2 26.9 4.8 ANO2 "C12orf3, TMEM16B" ENSG00000047617 "Anoctamin 2" Q9NQ90 12 5531869-5946232 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "retina: 226.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 81.3;Early spermatids: 57.3;Late spermatids: 283.2;Microglial cells: 143.4;Rod photoreceptor cells: 179.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 9.6;HUVEC TERT2: 9.5;U-2 OS: 24.1" "Region enriched" "Detected in many" 4 "basal ganglia: 19.6" "HPA036276, HPA057499" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 9: U-2 OS - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA036276: AB_10670713, HPA057499: AB_2732613" "unprognostic (6.32e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-1)" "unprognostic (1.25e-2)" "unprognostic (1.55e-1)" "unprognostic (4.05e-3)" "unprognostic (2.86e-1)" "unprognostic (2.62e-1)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-3)" "unprognostic (3.78e-3)" "unprognostic (1.04e-2)" "unprognostic (1.10e-2)" "unprognostic (9.93e-2)" "unprognostic (2.27e-1)" "unprognostic (2.17e-1)" 8.8 0.3 3.8 0.4 4.4 0.0 6.6 2.2 3.3 4.3 5.0 1.9 0.7 1.8 1.4 1.7 3.2 1.1 8.0 2.5 2.4 1.2 0.2 7.2 0.1 3.2 3.2 1.5 0.9 1.3 0.6 4.1 3.4 2.5 0.6 226.0 1.3 1.0 2.0 1.1 1.7 1.5 3.0 3.4 2.2 10.1 3.9 0.3 2.4 4.4 0.2 2.4 3.5 2.8 2.5 0.0 4.4 0.0 0.0 0.2 2.0 0.0 9.6 0.5 1.0 0.0 0.2 0.2 0.3 0.0 0.1 0.3 0.0 0.1 0.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.0 1.9 0.0 1.0 0.0 0.0 4.6 2.3 0.0 1.9 0.0 1.0 0.1 0.1 0.0 0.0 2.3 1.6 0.0 3.9 1.3 0.0 0.2 0.0 24.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.8 4.4 2.2 3.3 2.5 2.4 3.2 3.2 3.4 3.0 3.9 2.8 9.7 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.6 11.5 0.3 0.1 1.9 0.0 0.0 0.0 81.3 1.4 0.0 0.0 0.0 0.0 57.3 0.4 0.4 9.1 0.0 0.0 1.7 0.0 2.0 0.3 0.0 0.5 0.0 0.0 4.6 0.0 0.2 10.1 2.0 0.0 0.0 0.0 0.0 283.2 0.3 0.1 0.0 143.4 0.0 13.0 0.0 31.2 9.9 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 179.9 0.0 1.3 0.6 1.4 1.8 0.0 0.1 2.5 0.0 0.2 0.2 0.0 ANO6 "DKFZp313M0720, TMEM16F" ENSG00000177119 "Anoctamin 6" Q4KMQ2 12 45215987-45482280 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038958 Approved Approved "Plasma membrane,Cytosol" NA NA 47000 "Cluster 14: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 32: U-937 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA038958: AB_10672835" "prognostic unfavorable (7.56e-5)" "prognostic unfavorable (3.82e-4)" "unprognostic (2.16e-1)" "unprognostic (1.75e-2)" "unprognostic (1.29e-1)" "unprognostic (9.82e-3)" "unprognostic (7.43e-2)" "unprognostic (3.01e-3)" "unprognostic (7.55e-2)" "unprognostic (2.84e-3)" "unprognostic (1.41e-3)" "unprognostic (3.02e-1)" "unprognostic (2.68e-2)" "unprognostic (1.26e-3)" "unprognostic (1.26e-1)" "unprognostic (4.20e-2)" "unprognostic (1.28e-1)" 86.4 25.9 7.4 16.8 8.0 9.8 27.5 7.9 8.4 28.9 13.8 29.9 36.2 38.9 25.6 25.0 27.2 31.6 27.7 7.2 10.5 36.2 56.9 40.2 13.4 10.4 8.5 56.6 25.3 58.8 6.9 50.5 10.1 29.9 15.0 3.6 25.4 37.1 56.0 12.0 51.4 48.4 9.0 16.0 13.8 11.8 9.1 24.9 13.2 46.3 12.8 35.0 16.0 9.3 41.5 44.3 25.7 35.4 119.1 61.7 97.4 57.4 72.5 38.4 36.3 71.9 61.5 21.1 52.2 92.0 34.9 54.0 24.1 32.3 45.6 31.4 16.9 25.0 17.8 62.1 37.8 39.5 19.4 51.7 31.9 33.0 48.7 95.4 52.6 44.5 19.3 34.0 42.7 11.2 41.5 13.2 28.6 0.0 18.0 23.4 33.3 24.4 36.9 63.1 11.7 39.9 59.9 36.8 27.9 67.7 43.3 62.8 70.6 41.2 26.1 41.8 29.3 18.3 21.5 25.8 37.3 122.8 33.4 3.1 5.9 1.4 2.4 6.9 2.5 1.4 2.2 2.0 5.5 1.2 2.0 1.3 0.6 2.3 7.1 2.7 3.0 4.2 7.4 8.0 7.9 8.4 7.2 10.5 10.4 8.5 10.1 9.0 9.1 9.3 65.1 60.9 11.8 54.9 10.0 30.5 20.3 27.7 23.3 1.1 23.0 18.7 23.4 30.0 21.5 18.4 0.0 34.0 14.5 2.5 3.9 38.4 1.3 13.3 32.1 37.5 8.4 8.0 49.8 37.4 28.0 44.2 21.4 26.0 12.7 20.2 52.5 88.3 19.9 0.0 49.0 11.5 12.2 56.3 22.9 3.5 51.3 46.0 17.8 68.4 29.1 8.2 15.5 110.6 3.0 73.3 10.0 40.6 12.2 29.5 70.3 23.4 16.5 0.3 39.5 45.9 52.1 3.5 4.3 25.1 22.0 24.6 17.3 6.7 14.6 30.5 ANPEP "CD13, gp150, LAP1, p150, PEPN" ENSG00000166825 "Alanyl aminopeptidase, membrane" P15144 15 89784895-89815401 "CD markers, Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Aminopeptidase, Developmental protein, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 2384.1;pancreas: 675.0" "Cell type enriched" "Detected in many" 14 "Proximal enterocytes: 6315.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "cerebral cortex: 9.2;thalamus: 17.4" "Immune cell enriched" "Detected in many" 4 "neutrophil: 227.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 227.1" "Cell line enhanced" "Detected in many" "ASC diff: 613.7;ASC TERT1: 764.2;BJ: 738.4;BJ hTERT+: 1135.6;fHDF/TERT166: 703.8;HMC-1: 660.3;HSkMC: 670.0;HUVEC TERT2: 874.8;TIME: 815.1;U-2197: 891.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 14.8" "CAB002417, HPA004625" Enhanced Supported "Plasma membrane" NA NA 1200000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002417: AB_563491, HPA004625: AB_2667199" "unprognostic (6.31e-2)" "unprognostic (7.94e-3)" "unprognostic (6.91e-2)" "unprognostic (2.16e-1)" "unprognostic (2.50e-1)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (7.73e-2)" "unprognostic (5.28e-3)" "unprognostic (3.96e-1)" "unprognostic (4.04e-3)" "unprognostic (3.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.61e-3)" "unprognostic (1.99e-2)" 55.4 7.0 1.6 36.6 1.6 103.4 55.9 1.3 9.2 41.4 3.4 266.8 2384.1 3.6 1.7 4.8 8.0 120.3 6.9 1.3 1.5 249.7 271.8 34.3 12.8 1.5 2.1 1.9 675.0 0.8 1.9 33.1 2.5 94.0 59.9 0.0 42.1 5.5 2.5 32.5 1970.6 29.7 1.3 25.9 8.0 2.0 17.4 7.1 8.2 3.8 4.7 16.8 15.0 1.2 0.1 45.6 0.0 0.5 613.7 764.2 6.2 738.4 1135.6 95.3 81.6 5.8 0.4 0.2 8.4 703.8 0.0 0.6 5.6 0.2 38.6 0.1 0.1 137.3 4.6 122.8 352.0 11.4 660.3 670.0 1.4 302.3 0.3 4.4 874.8 0.0 3.8 0.8 37.8 0.1 0.6 355.4 1.9 0.0 49.9 0.3 0.1 9.5 449.2 0.0 1.2 7.2 0.1 1.3 0.1 1.8 0.5 72.1 815.1 385.3 0.6 891.4 0.1 0.4 0.1 0.1 0.9 0.9 20.5 22.2 56.3 41.1 0.1 27.4 0.0 0.2 0.0 0.0 26.2 0.2 0.0 0.0 227.1 0.0 49.7 0.7 0.0 25.7 1.6 1.6 1.3 9.2 1.3 1.5 1.5 2.1 2.5 1.3 17.4 1.2 2.4 0.0 3.0 0.0 5.2 9.9 2.8 1.4 0.6 0.0 35.7 12.8 1.2 391.7 19.7 20.2 0.0 13.0 0.7 429.8 43.0 15.4 0.2 0.5 10.1 8.4 3.0 6.6 0.3 386.2 16.3 31.0 0.0 0.4 24.1 0.3 79.2 192.4 37.5 0.0 0.3 199.6 2.0 54.1 63.2 0.2 2.8 71.9 3.6 0.0 38.3 0.0 0.0 0.0 0.1 75.5 316.9 1.5 2.1 20.9 6315.2 435.0 3.3 0.0 26.3 0.8 8.1 0.3 0.5 0.2 5.8 6.4 3.7 187.8 290.9 1.4 ANXA1 "ANX1, LPC1" ENSG00000135046 "Annexin A1" P04083 9 73151865-73170393 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Phospholipase A2 inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 7527.7" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 3632.9;Syncytiotrophoblasts: 7071.8;Urothelial cells: 4808.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 2816.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011271, HPA011272, CAB013023, CAB035987, CAB058693" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA Yes 3000000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" Nucleoplasm "CAB013023: AB_2533983, CAB035987: , CAB058693: AB_2665585, HPA011271: AB_1844883, HPA011272: AB_1844884" "unprognostic (2.53e-2)" "unprognostic (1.31e-1)" "unprognostic (9.08e-2)" "prognostic favorable (5.71e-5)" "unprognostic (1.53e-2)" "unprognostic (4.28e-2)" "unprognostic (1.82e-2)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-3)" "unprognostic (1.47e-1)" "unprognostic (9.82e-3)" "unprognostic (1.13e-1)" "unprognostic (8.55e-2)" "prognostic favorable (4.57e-5)" "prognostic unfavorable (6.19e-6)" 719.8 60.3 27.5 268.3 35.1 2132.2 442.6 24.8 44.4 952.0 32.8 152.7 64.1 116.2 58.6 7527.7 264.6 329.4 145.3 28.4 53.4 67.9 54.7 470.4 67.9 55.5 46.4 109.4 61.8 28.2 98.1 559.4 36.5 165.3 103.2 6.5 1547.5 154.9 47.6 213.8 88.7 261.5 40.4 79.6 90.2 17.9 45.9 109.9 206.8 89.1 1485.5 386.3 1536.1 43.2 960.2 1485.7 65.8 68.4 905.8 855.6 4.2 1614.6 1008.5 656.3 441.9 43.5 841.0 2.2 520.1 1426.5 1441.9 1147.7 142.6 984.1 516.8 541.6 10.3 73.2 398.5 1.4 719.4 160.9 34.7 495.7 800.6 664.7 1294.6 604.0 947.8 85.4 309.3 39.5 822.6 4.3 287.0 87.7 82.6 379.7 597.6 0.9 369.1 3.2 1495.9 200.4 1.0 0.7 556.6 14.7 377.9 862.7 3.5 24.3 1176.2 761.8 478.9 1058.2 845.1 6.8 2.0 3.6 1757.9 147.8 1171.2 2816.9 1237.6 2227.6 744.1 328.7 757.0 13.7 662.7 664.5 1513.3 3.3 190.7 348.5 128.4 443.6 324.0 53.2 134.5 2021.5 27.5 35.1 24.8 44.4 28.4 53.4 55.5 46.4 36.5 40.4 45.9 43.2 447.4 583.3 415.2 1.6 39.0 846.7 2486.8 2417.6 1748.3 0.1 225.0 417.1 22.5 58.6 2214.7 62.5 0.0 1543.4 602.1 32.2 0.0 167.4 8.2 2037.4 241.6 362.2 5.3 81.2 3.7 23.1 1747.7 732.0 86.6 1993.5 2550.6 0.1 136.7 6.5 593.8 0.0 0.1 20.8 1330.6 545.0 1190.3 7.3 222.4 901.7 307.7 29.0 575.0 0.2 319.3 0.5 0.6 733.2 5.5 9.4 140.4 1552.2 0.1 5.7 1996.9 0.0 65.7 728.2 413.3 2.3 4.0 3632.9 597.7 7071.8 1348.3 3.0 12.6 4808.1 ANXA13 ANX13 ENSG00000104537 "Annexin A13" P27216 8 123680794-123737402 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 144.3;intestine: 293.6" "Cell type enhanced" "Detected in some" "Cholangiocytes: 180.1;Enteroendocrine cells: 44.9;Intestinal goblet cells: 161.1;Paneth cells: 58.1;Proximal enterocytes: 125.2;Undifferentiated cells: 38.5" "Group enriched" "Detected in many" 13 "colorectal cancer: 7.8;liver cancer: 8.5;pancreatic cancer: 6.1;renal cancer: 7.0;stomach cancer: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A549: 27.8;HDLM-2: 14.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018535, HPA019569, HPA019650, CAB025135" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" Nucleoplasm "CAB025135: , HPA018535: AB_1844854, HPA019569: AB_1844855, HPA019650: AB_1844856" "unprognostic (6.47e-3)" "unprognostic (1.95e-1)" "unprognostic (3.50e-2)" "unprognostic (1.83e-1)" "unprognostic (5.66e-2)" "unprognostic (4.05e-2)" "unprognostic (5.48e-2)" "unprognostic (2.86e-3)" "unprognostic (2.06e-1)" "unprognostic (9.11e-2)" "unprognostic (2.48e-2)" "unprognostic (2.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.49e-1)" "unprognostic (1.03e-1)" "unprognostic (5.79e-2)" "unprognostic (4.79e-2)" 0.2 0.0 1.1 1.6 2.6 0.0 0.4 2.6 2.2 0.4 1.1 21.6 293.6 1.5 2.2 0.2 58.4 144.3 0.1 1.1 1.5 7.0 20.2 0.2 0.2 4.1 2.9 0.4 0.4 0.0 0.0 0.0 3.3 0.5 36.1 4.3 0.1 24.3 0.0 0.1 219.5 2.9 3.3 0.0 0.8 4.2 2.1 0.1 0.0 0.0 0.0 0.5 0.1 5.3 0.0 27.8 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 14.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.0 0.0 0.0 0.0 1.7 1.6 0.0 0.1 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.6 2.6 2.2 1.1 1.5 4.1 2.9 3.3 3.3 2.1 5.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.1 0.0 0.2 0.1 1.1 0.4 180.1 0.0 0.0 0.0 0.0 0.0 6.2 3.9 1.4 1.1 4.5 3.6 0.2 44.9 2.7 0.9 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.1 0.2 0.0 1.0 161.1 0.0 0.0 0.0 1.4 1.2 0.3 0.0 0.0 0.0 0.3 0.0 0.5 1.2 0.1 58.1 0.0 0.0 0.0 125.2 27.6 2.9 10.9 0.0 0.2 0.1 0.0 0.1 0.0 0.6 0.0 0.4 0.1 38.5 0.1 ANXA3 ANX3 ENSG00000138772 "Annexin A3" P12429 4 78551747-78610451 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phospholipase A2 inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 337.7" "Cell type enhanced" "Detected in many" "Adipocytes: 322.7;Alveolar cells type 1: 589.7;Ductal cells: 434.5;Exocrine glandular cells: 305.3;Pancreatic endocrine cells: 754.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 320 "neutrophil: 207.7" "Lineage enriched" "Detected in single" 327 "granulocytes: 207.7" "Cell line enhanced" "Detected in many" "A-431: 419.5;CACO-2: 403.5;CAPAN-2: 563.7;EFO-21: 334.7;hTERT-HME1: 566.3;OE19: 502.1;RPTEC TERT1: 477.8" "Low region specificity" "Detected in all" "HPA013398, HPA013431" Enhanced Supported "Plasma membrane" NA NA 6400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "HPA013398: AB_1844861, HPA013431: AB_1844862" "unprognostic (2.66e-1)" "unprognostic (5.65e-3)" "unprognostic (4.92e-3)" "unprognostic (8.67e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-3)" "unprognostic (4.17e-2)" "unprognostic (1.87e-1)" "unprognostic (5.09e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (1.28e-4)" "unprognostic (4.82e-2)" "prognostic favorable (8.48e-6)" "unprognostic (2.23e-1)" "unprognostic (2.02e-2)" "unprognostic (7.20e-2)" "unprognostic (3.30e-2)" 52.9 3.1 16.5 22.7 17.3 337.7 43.8 14.5 28.2 19.6 11.7 27.7 15.8 12.5 3.7 55.2 16.8 17.3 51.2 14.2 21.6 24.9 3.9 144.4 2.4 19.9 16.1 2.5 32.7 34.0 5.9 81.5 20.8 68.0 26.7 1.6 119.5 12.9 28.3 10.0 13.3 20.1 14.6 21.6 90.5 1.9 19.9 7.1 83.7 36.7 12.7 10.2 15.6 14.7 419.5 77.7 1.3 0.9 1.0 0.9 0.6 4.9 0.4 11.0 10.9 403.5 563.7 0.1 334.7 14.4 0.4 161.6 0.1 300.0 16.0 1.4 3.3 36.4 142.0 23.9 45.9 5.9 0.2 2.4 262.6 4.1 566.3 60.1 118.9 9.0 0.7 0.3 1.9 15.9 1.7 0.2 13.0 502.1 55.4 0.0 0.8 0.0 477.8 45.2 0.3 0.3 235.5 58.2 16.6 186.1 9.9 4.3 153.2 0.6 52.6 0.2 93.0 3.1 5.1 2.2 0.0 0.4 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.4 0.1 0.0 207.7 0.1 0.6 0.1 0.0 2.9 16.5 17.3 14.5 28.2 14.2 21.6 19.9 16.1 20.8 14.6 19.9 14.7 322.7 589.7 47.3 0.0 1.1 24.9 81.8 144.9 1.8 0.2 27.6 85.9 8.6 55.8 175.2 38.6 0.0 212.6 1.0 35.4 17.6 434.5 1.1 33.7 4.4 84.6 5.4 3.2 0.9 305.3 106.2 16.9 99.9 58.1 5.1 0.1 23.2 0.6 18.9 0.0 0.3 33.4 122.1 0.3 0.3 0.3 3.1 6.9 5.4 42.2 21.0 1.2 0.0 1.0 0.6 754.2 61.6 0.4 0.6 158.6 11.5 5.5 89.6 0.4 0.0 7.6 18.7 1.1 0.6 21.9 6.7 62.8 2.3 1.3 29.7 46.7 AP2M1 "AP50, CLAPM1, mu2" ENSG00000161203 "Adaptor related protein complex 2 subunit mu 1" Q96CW1 3 184174689-184184091 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036849, HPA069870" Uncertain Supported "Plasma membrane" NA NA 7500 "Cluster 31: Non-specific - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "HPA036849: AB_10672101, HPA069870: AB_2686217" "unprognostic (1.16e-1)" "unprognostic (1.35e-2)" "unprognostic (5.28e-3)" "unprognostic (4.96e-3)" "unprognostic (1.79e-1)" "unprognostic (2.88e-2)" "prognostic unfavorable (9.12e-4)" "unprognostic (3.80e-3)" "unprognostic (2.09e-1)" "unprognostic (5.53e-2)" "unprognostic (4.11e-2)" "unprognostic (9.18e-2)" "prognostic unfavorable (7.45e-6)" "unprognostic (2.61e-2)" "unprognostic (4.09e-2)" "unprognostic (1.60e-2)" "unprognostic (1.28e-1)" 191.8 364.2 233.5 164.7 250.3 231.3 164.6 211.3 257.3 222.8 196.3 232.4 167.5 216.4 104.2 218.1 178.6 166.5 366.2 261.1 249.0 196.0 140.9 180.0 148.2 234.8 211.1 198.6 106.4 224.8 224.9 243.3 248.9 183.2 141.1 230.4 167.2 231.8 181.2 157.2 156.2 243.7 200.9 162.5 156.3 106.4 235.4 158.4 148.0 194.0 157.6 223.7 192.4 225.6 436.3 327.5 275.7 311.8 432.1 450.8 284.3 714.3 412.5 788.5 550.5 355.1 309.9 198.2 851.3 1076.1 516.1 480.0 376.3 482.9 647.1 409.8 470.4 512.2 365.8 317.9 508.9 254.8 311.5 577.0 269.4 501.1 318.5 711.0 595.3 258.3 250.0 377.1 750.1 993.6 330.1 151.2 674.1 388.1 484.7 302.7 351.5 393.7 489.7 389.3 292.0 212.6 561.3 696.4 335.1 427.5 934.4 305.7 645.0 497.1 400.1 492.4 960.2 336.9 318.7 441.6 937.1 369.9 331.7 194.4 294.8 244.9 137.5 238.8 136.2 114.3 127.6 134.0 268.7 112.7 107.7 111.8 127.7 170.2 206.8 134.1 185.4 441.0 233.5 250.3 211.3 257.3 261.1 249.0 234.8 211.1 248.9 200.9 235.4 225.6 146.8 54.5 50.7 41.4 84.8 124.9 177.2 275.1 97.9 174.2 108.0 98.2 195.9 112.9 133.5 114.0 70.9 400.9 117.3 155.9 375.6 243.7 326.6 69.3 131.2 172.2 140.8 277.8 62.0 161.3 327.1 161.5 71.4 78.5 149.1 173.6 182.4 78.0 576.9 277.6 63.4 119.0 201.4 137.1 162.9 347.8 164.7 185.1 199.3 34.7 369.4 199.4 130.7 26.2 46.1 232.1 153.1 214.8 100.2 138.8 253.8 290.7 58.3 125.9 197.2 106.9 278.0 83.3 101.7 128.5 126.6 513.6 102.6 278.1 154.1 185.1 APBB1 "Fe65, RIR" ENSG00000166313 "Amyloid beta precursor protein binding family B member 1" O00213 11 6395124-6419414 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, Transcription, Transcription regulation" "Activator, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.9" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 85.6" "Lineage enriched" "Detected in all" 5 "T-cells: 85.6" "Cell line enhanced" "Detected in many" "SCLC-21H: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038521, HPA038522" Approved Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "HPA038521: AB_2676058, HPA038522: AB_2676059" "unprognostic (4.76e-2)" "unprognostic (1.98e-1)" "unprognostic (4.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.84e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (7.30e-2)" "unprognostic (3.22e-3)" "unprognostic (2.36e-1)" "prognostic favorable (1.86e-5)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-13)" "unprognostic (1.32e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (1.09e-2)" 18.1 23.8 101.7 11.9 119.4 2.7 18.0 116.6 121.1 39.5 65.1 43.3 7.0 43.5 4.3 14.9 38.3 11.4 42.0 123.3 105.3 21.5 3.8 22.5 13.9 123.9 106.0 39.2 16.3 21.4 61.3 8.6 135.0 23.7 4.7 23.3 13.4 25.9 42.3 12.2 19.2 33.2 109.4 13.8 19.4 12.7 112.1 28.9 19.1 54.0 11.1 31.2 23.5 152.9 0.0 14.9 50.6 22.8 26.7 27.4 0.2 24.6 41.7 41.2 51.4 26.4 10.3 0.0 3.6 44.3 36.9 0.5 44.4 7.5 19.4 27.8 33.7 0.3 9.3 0.9 19.3 0.2 9.9 24.8 1.9 19.4 2.9 35.3 51.7 1.2 1.1 0.7 15.3 0.5 0.5 0.1 18.3 0.8 15.5 0.2 2.0 0.2 1.7 0.2 68.1 37.6 3.6 3.0 15.9 15.2 2.1 3.4 22.8 4.2 24.8 27.5 5.0 13.8 6.8 2.0 21.1 0.0 14.3 8.4 1.7 0.3 23.2 1.5 25.2 6.7 32.5 30.2 1.7 16.2 85.6 51.7 1.6 16.5 0.6 0.3 48.7 29.9 101.7 119.4 116.6 121.1 123.3 105.3 123.9 106.0 135.0 109.4 112.1 152.9 9.6 19.2 5.4 22.9 7.5 5.0 12.1 3.6 12.0 45.8 6.6 5.7 50.5 11.5 5.4 5.5 22.9 0.4 4.6 1.1 25.4 18.2 5.6 7.6 9.5 13.9 19.3 4.0 47.1 4.2 0.7 15.2 4.6 2.3 1.3 10.8 15.7 3.3 1.2 40.4 44.8 1.2 0.0 1.9 4.0 13.1 9.6 1.8 8.8 7.5 3.2 24.7 9.2 49.3 102.3 8.0 1.7 19.2 1.4 8.3 0.4 21.6 17.3 20.1 6.6 10.0 17.3 6.9 13.7 3.2 2.8 0.8 20.1 7.0 1.3 5.4 AQP1 "CHIP28, CO" ENSG00000240583 "Aquaporin 1 (Colton blood group)" P29972 7 30911853-30925517 "Blood group antigen proteins, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 727.9;Alveolar cells type 2: 231.8;Cholangiocytes: 358.9;Endothelial cells: 606.7;Hepatic stellate cells: 325.6;Proximal tubular cells: 319.7" "Cancer enhanced" "Detected in all" "glioma: 336.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 34.7;HeLa: 12.5;SH-SY5Y: 14.7;U-2 OS: 14.9;WM-115: 76.4" "Group enriched" "Detected in some" 6 "medulla oblongata: 5.5;spinal cord: 22.0" "CAB001707, HPA019206" Enhanced Supported "Plasma membrane" NA NA 49000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB001707: , HPA019206: AB_1844965" "unprognostic (4.18e-2)" "unprognostic (7.82e-3)" "unprognostic (1.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "prognostic favorable (6.52e-4)" "unprognostic (1.95e-3)" "unprognostic (1.66e-1)" "unprognostic (3.00e-2)" "unprognostic (3.80e-2)" "unprognostic (4.16e-1)" "unprognostic (2.05e-2)" "prognostic favorable (1.32e-8)" "unprognostic (3.43e-2)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (7.21e-2)" 385.9 30.5 86.5 29.3 149.4 50.7 250.3 106.2 79.1 148.9 277.7 97.7 51.0 160.8 41.7 143.5 165.8 162.3 206.8 141.0 124.4 522.9 12.9 413.9 45.5 512.3 181.1 28.1 257.6 48.2 15.2 36.9 199.5 83.8 32.6 0.7 114.0 84.4 199.0 112.6 90.8 142.4 357.3 12.6 80.4 7.8 138.8 39.0 113.2 388.6 34.2 138.5 143.2 432.4 0.1 0.5 0.3 0.6 0.3 1.3 0.7 2.4 0.5 0.0 0.0 0.2 0.8 0.1 34.7 1.9 0.1 0.4 0.0 0.0 0.0 0.3 0.3 0.5 12.5 0.0 0.3 0.3 0.1 4.9 0.1 0.3 0.0 0.1 5.1 0.1 2.3 0.1 0.0 0.0 0.0 0.9 0.7 1.0 0.0 0.0 8.9 0.3 0.9 0.0 0.3 14.7 1.9 1.2 0.0 4.6 0.3 0.1 0.0 0.0 14.9 1.1 0.5 0.8 0.6 0.6 0.0 0.1 76.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 86.5 149.4 106.2 79.1 141.0 124.4 512.3 181.1 199.5 357.3 138.8 432.4 727.9 179.5 231.8 75.7 3.6 91.5 1.2 0.3 5.2 0.7 11.5 29.0 78.0 358.9 3.9 31.3 8.4 3.4 3.7 3.7 29.4 53.3 2.3 2.5 1.2 606.7 7.3 86.9 3.5 2.5 4.8 67.6 0.0 0.9 1.3 0.5 325.6 2.0 3.7 0.0 1.0 28.6 0.0 5.1 107.7 2.1 1.2 6.0 88.9 0.0 1.6 0.4 0.0 0.5 0.2 2.4 14.5 3.4 3.7 1.2 90.6 319.7 6.2 0.4 13.1 23.1 42.3 0.3 1.5 2.6 78.7 7.3 8.1 4.7 67.8 1.0 AQP10 ENSG00000143595 "Aquaporin 10" Q96PS8 1 154321090-154325325 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "intestine: 68.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.5;Erythroid cells: 1.3;granulocytes: 5.7;Hepatic stellate cells: 1.4;Macrophages: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.0;HMC-1: 7.1;K-562: 21.0;SH-SY5Y: 4.8" "Not detected" "Not detected" "HPA062621, HPA065947" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" Vesicles "HPA062621: , HPA065947: AB_2685584" "unprognostic (6.84e-2)" "unprognostic (4.97e-2)" "unprognostic (4.19e-2)" "unprognostic (1.87e-1)" "unprognostic (1.09e-1)" "unprognostic (8.45e-4)" "unprognostic (1.63e-1)" "unprognostic (3.07e-1)" "unprognostic (4.08e-2)" "unprognostic (3.99e-1)" "unprognostic (1.22e-1)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-1)" "unprognostic (7.64e-3)" 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 68.5 0.0 0.1 0.1 4.6 0.1 0.4 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 49.7 0.0 0.0 0.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 21.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.1 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.1 5.7 0.2 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.1 0.0 0.4 0.1 0.0 0.1 AQP3 GIL ENSG00000165272 "Aquaporin 3 (Gill blood group)" Q92482 9 33441156-33447596 "Blood group antigen proteins, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1526.1;skin 1: 581.9;urinary bladder: 688.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1923.3;Basal prostatic cells: 982.0;Collecting duct cells: 1609.3;Prostatic glandular cells: 1430.8;Squamous epithelial cells: 2189.3;Suprabasal keratinocytes: 2485.4;Urothelial cells: 2455.4" "Group enriched" "Detected in all" 5 "cervical cancer: 319.0;head and neck cancer: 283.7;lung cancer: 146.8;urothelial cancer: 221.3" "Group enriched" "Detected in many" 4 "hippocampal formation: 5.3;medulla oblongata: 16.0;pons: 21.0" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 181.7;T-reg: 205.4" "Lineage enriched" "Detected in many" 18 "T-cells: 205.4" "Cell line enhanced" "Detected in many" "HaCaT: 127.1;HeLa: 213.2;JURKAT: 130.7;RT4: 216.6;SK-BR-3: 149.7;U-266/70: 151.2;U-266/84: 213.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014924 Enhanced Supported "Plasma membrane" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA014924: AB_2669120" "unprognostic (4.29e-2)" "prognostic favorable (5.31e-4)" "unprognostic (1.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.84e-2)" "unprognostic (1.11e-2)" "unprognostic (9.95e-2)" "unprognostic (1.64e-1)" "unprognostic (3.46e-1)" "unprognostic (9.06e-2)" "unprognostic (4.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (1.16e-2)" "unprognostic (2.59e-1)" "unprognostic (3.73e-2)" "unprognostic (4.51e-2)" 10.9 2.1 1.5 16.8 0.4 19.7 36.6 2.4 3.4 173.3 1.4 10.3 73.4 10.9 2.9 1526.1 25.4 9.4 31.5 5.3 0.4 131.7 118.6 114.0 16.1 16.0 1.6 12.1 43.1 2.0 2.8 6.0 21.0 85.6 10.1 1.7 399.7 36.8 5.3 581.9 100.5 3.2 0.2 110.1 35.9 2.8 0.8 233.9 2.3 26.7 172.5 688.6 529.9 0.9 0.6 38.6 1.9 0.0 67.7 12.2 1.0 0.3 0.9 0.9 1.1 20.5 12.0 0.5 9.1 0.0 0.5 127.1 6.2 0.7 0.2 61.6 6.0 4.3 213.2 1.9 0.4 1.3 1.3 1.9 6.5 0.5 0.2 0.2 0.5 130.7 67.4 58.8 6.9 29.1 60.4 23.0 5.3 88.6 0.7 0.9 94.3 10.8 1.3 216.6 1.7 4.7 32.3 149.7 0.1 8.0 0.9 10.6 1.2 0.0 1.0 0.4 0.4 151.2 213.6 14.5 0.5 0.4 0.2 1.6 0.5 0.1 20.2 0.4 181.7 11.3 171.9 52.8 0.3 3.0 97.3 47.1 2.3 3.0 0.5 11.1 205.4 43.0 1.5 0.4 2.4 3.4 5.3 0.4 16.0 1.6 21.0 0.2 0.8 0.9 9.2 38.5 249.9 0.0 42.4 1923.3 982.0 381.4 811.0 9.7 56.8 27.8 3.4 157.3 436.3 1609.3 2.1 0.9 21.6 2.7 0.0 37.4 2.2 82.3 21.4 37.1 8.3 71.4 0.3 48.9 2.0 27.5 16.3 96.2 20.8 0.2 16.4 137.3 2.2 0.0 0.1 104.0 315.3 3.5 122.9 0.6 33.2 15.3 158.3 0.0 1.6 0.4 4.1 0.5 0.2 28.5 8.1 1.2 246.9 1430.8 343.1 31.9 546.0 0.5 0.0 10.2 35.8 0.7 1.9 2189.3 2485.4 50.2 73.4 1.6 7.3 2455.4 AQP4 MIWC ENSG00000171885 "Aquaporin 4" P55087 18 26852043-26865771 "Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 440.5;lung: 114.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 1102.6;Alveolar cells type 2: 342.3;Astrocytes: 487.7;Muller glia cells: 227.2" "Cancer enriched" "Detected in some" 22 "glioma: 223.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.4;RPTEC TERT1: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005079, HPA014784, CAB058689" Enhanced Supported Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions" "CAB005079: AB_2274338, CAB058689: AB_2665579, HPA014784: AB_1844967" "unprognostic (7.23e-5)" "unprognostic (1.55e-1)" "unprognostic (3.19e-8)" "unprognostic (3.68e-1)" "unprognostic (1.96e-1)" "unprognostic (2.69e-2)" "unprognostic (1.74e-1)" "unprognostic (2.34e-1)" "unprognostic (5.38e-3)" "unprognostic (1.64e-3)" "unprognostic (8.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.14e-2)" "unprognostic (1.35e-1)" "unprognostic (4.10e-2)" 0.1 0.1 272.7 0.0 298.7 0.0 0.3 282.0 246.3 0.6 62.9 0.3 0.0 0.0 0.8 0.9 1.1 0.1 2.8 283.6 440.5 2.3 0.9 114.8 0.3 250.5 351.2 2.5 0.2 2.2 3.7 0.0 333.3 0.4 0.0 60.2 0.7 0.2 60.1 0.1 0.1 0.0 333.0 0.5 11.4 0.5 387.1 0.2 14.7 20.9 0.1 0.1 0.1 376.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 272.7 298.7 282.0 246.3 283.6 440.5 250.5 351.2 333.3 333.0 387.1 376.0 0.0 1102.6 342.3 487.7 0.0 0.0 0.8 0.6 0.0 3.1 0.8 0.9 13.9 4.3 76.6 3.7 6.2 0.0 0.0 0.1 3.9 0.3 0.0 0.7 0.1 1.8 0.0 0.0 3.0 0.0 0.0 0.8 0.0 0.0 3.8 0.0 0.0 0.5 0.0 1.7 1.1 0.0 0.0 0.0 0.3 0.0 5.0 0.8 0.0 9.4 0.0 227.2 0.0 12.1 1.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.1 9.1 0.0 4.3 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 2.0 ARHGAP17 "FLJ10308, FLJ13219, NADRIN, RICH1, WBP15" ENSG00000140750 "Rho GTPase activating protein 17" Q68EM7 16 24919389-25015666 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041703, HPA075891" Approved Supported "Plasma membrane,Cytosol" NA NA 21000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA041703: AB_10794304, HPA075891: " "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (8.11e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.42e-2)" "unprognostic (3.49e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (3.02e-2)" "unprognostic (6.62e-2)" "unprognostic (8.81e-3)" "unprognostic (4.99e-2)" "unprognostic (3.45e-2)" "unprognostic (1.38e-2)" "unprognostic (1.94e-1)" "unprognostic (3.91e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.76e-4)" 46.0 40.5 8.2 15.2 9.8 9.2 37.2 9.2 10.2 29.9 9.6 32.7 11.3 28.9 7.9 33.6 28.6 11.9 48.1 7.9 9.2 25.9 22.9 31.8 24.9 10.6 9.5 24.8 24.1 9.3 30.3 15.3 10.4 23.6 12.2 2.3 21.3 7.9 41.0 34.3 39.2 11.6 8.7 66.8 28.9 25.5 9.7 12.0 28.2 11.1 20.9 25.6 29.8 11.6 28.5 16.7 21.9 23.1 22.0 23.0 23.7 18.1 19.3 20.9 20.4 25.9 11.5 13.0 12.0 36.4 19.9 7.7 21.8 12.8 22.2 20.0 26.1 10.8 37.8 43.3 25.0 15.5 10.7 29.4 7.7 22.6 16.3 15.0 35.7 11.7 14.3 0.0 23.6 20.8 14.3 19.8 25.2 8.1 13.7 68.1 17.9 5.2 25.9 6.4 14.6 14.5 18.6 20.5 8.2 17.5 11.1 40.2 46.7 15.5 11.9 35.6 15.1 13.0 17.3 7.5 19.1 22.6 14.1 5.6 9.7 9.0 6.3 17.5 5.7 25.3 5.5 6.3 14.6 22.8 6.2 6.1 4.8 6.2 15.8 25.9 8.0 8.1 8.2 9.8 9.2 10.2 7.9 9.2 10.6 9.5 10.4 8.7 9.7 11.6 33.8 9.6 11.0 26.8 46.3 14.5 6.8 8.9 14.2 6.4 11.0 9.7 24.9 7.2 9.1 5.5 10.4 11.1 36.3 49.5 3.9 13.3 6.3 30.6 21.8 32.3 21.0 16.2 28.8 16.0 18.9 16.0 15.3 66.4 7.0 16.9 26.7 6.8 27.1 10.1 33.0 21.8 8.2 30.3 21.7 10.8 13.4 25.2 16.0 59.0 22.8 6.4 14.4 40.2 68.9 17.6 27.2 11.7 11.5 11.1 35.4 5.0 8.5 7.5 26.3 15.5 43.8 7.0 11.7 24.7 24.0 15.7 21.1 15.9 19.7 12.2 ARHGAP21 "ARHGAP10, KIAA1424" ENSG00000107863 "Rho GTPase activating protein 21" Q5T5U3 10 24583609-24723887 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 111.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 266.5;Oligodendrocyte precursor cells: 336.7;Oligodendrocytes: 827.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036610, HPA057861" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Cell Junctions, Actin filaments" "Plasma membrane" "HPA036610: AB_10669910, HPA057861: AB_2683546" "unprognostic (7.65e-2)" "unprognostic (1.61e-2)" "unprognostic (1.88e-1)" "unprognostic (5.84e-2)" "unprognostic (2.69e-1)" "unprognostic (3.59e-1)" "unprognostic (1.12e-3)" "unprognostic (5.35e-2)" "unprognostic (9.75e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-3)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" "unprognostic (1.53e-1)" "unprognostic (3.32e-1)" "unprognostic (1.43e-2)" "unprognostic (2.61e-2)" 28.4 18.0 44.3 10.3 77.7 7.2 16.1 56.7 58.1 19.7 0.0 16.6 12.9 19.9 8.6 10.8 17.5 17.9 21.2 49.1 48.3 11.0 13.1 21.7 5.3 76.3 63.1 31.9 14.9 14.6 12.1 16.6 66.7 10.8 18.5 41.3 24.5 11.5 17.7 6.8 16.3 17.8 48.4 8.9 27.1 14.6 58.0 11.4 12.8 23.0 6.0 13.8 9.0 111.2 59.0 25.1 60.9 52.3 42.2 59.1 21.6 41.6 26.6 24.5 34.0 18.4 36.8 10.9 14.0 64.3 37.7 38.1 31.6 40.4 35.9 38.0 20.5 64.9 54.7 13.8 25.5 0.0 9.9 24.4 45.0 32.1 34.4 36.9 42.3 16.1 27.9 96.3 50.0 11.6 30.2 2.3 9.7 20.8 13.6 7.0 21.4 6.2 17.2 10.2 10.5 10.9 27.9 16.0 32.6 18.1 16.3 9.1 47.8 35.3 22.7 40.0 30.6 11.0 20.3 7.8 36.2 11.4 24.7 0.9 0.2 0.4 0.1 0.4 0.1 0.0 0.2 0.3 0.3 0.0 0.6 0.3 0.0 0.2 0.2 0.4 0.4 0.2 44.3 77.7 56.7 58.1 49.1 48.3 76.3 63.1 66.7 48.4 58.0 111.2 47.9 86.6 33.1 246.8 6.5 29.6 13.2 23.6 14.8 144.0 17.5 26.0 37.4 24.3 45.0 5.5 68.8 23.8 6.9 44.6 1.9 21.4 5.0 36.2 148.7 34.9 16.2 15.2 266.5 27.6 21.0 73.0 82.0 54.2 17.1 135.8 26.0 20.9 14.6 132.9 153.8 28.3 14.2 32.8 31.8 8.3 92.9 38.9 19.6 171.4 11.0 194.0 2.1 336.7 827.4 37.1 34.6 59.5 15.2 27.4 21.9 6.5 30.3 53.5 26.3 60.4 43.2 27.4 35.6 18.1 20.2 12.6 11.8 62.2 29.0 29.5 ARHGAP22 RhoGAP2 ENSG00000128805 "Rho GTPase activating protein 22" Q7Z5H3 10 48446036-48656265 "Predicted intracellular proteins" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.6" "Cell type enhanced" "Detected in many" "Late spermatids: 122.7;Microglial cells: 227.7;Oligodendrocyte precursor cells: 141.8;Oligodendrocytes: 200.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 68.8;LHCN-M2: 64.8;TIME: 66.2;U-87 MG: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020696, HPA040391, HPA064439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB020696: , HPA040391: AB_2676957, HPA064439: AB_2685266" "unprognostic (1.87e-1)" "unprognostic (3.98e-2)" "unprognostic (2.38e-2)" "unprognostic (2.62e-1)" "unprognostic (1.07e-1)" "unprognostic (6.74e-3)" "unprognostic (4.81e-3)" "unprognostic (2.78e-1)" "unprognostic (1.66e-1)" "unprognostic (3.03e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (2.16e-8)" "unprognostic (7.40e-2)" "unprognostic (1.60e-1)" "unprognostic (9.39e-2)" "unprognostic (3.66e-2)" 2.6 1.9 12.0 3.0 15.7 1.4 1.6 17.6 14.5 1.6 7.7 2.0 0.6 1.1 0.7 1.4 1.8 1.8 4.4 11.9 12.7 1.3 0.8 2.0 2.7 22.6 17.0 4.8 1.7 0.9 2.0 0.8 20.1 3.3 1.0 0.4 2.0 1.1 1.9 2.2 1.6 1.4 16.9 2.8 1.2 4.8 17.0 2.8 6.6 1.6 2.2 2.1 2.2 22.2 6.2 1.4 0.4 0.0 5.1 20.8 4.3 31.9 15.1 3.0 4.1 7.0 0.9 0.0 1.2 13.1 2.1 12.4 0.4 11.2 5.4 0.6 11.5 18.2 0.2 0.1 2.7 2.0 2.0 5.0 11.2 37.1 3.0 68.8 20.6 0.0 17.4 3.0 64.8 0.2 0.2 0.1 7.2 0.0 0.5 0.1 0.0 7.9 6.5 0.7 1.1 6.4 1.5 0.1 0.6 0.6 0.4 0.3 66.2 30.1 0.4 3.8 23.8 0.0 0.0 0.0 82.5 0.3 4.9 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 12.0 15.7 17.6 14.5 11.9 12.7 22.6 17.0 20.1 16.9 17.0 22.2 0.9 0.0 1.7 4.2 2.9 3.4 4.1 6.8 4.6 1.1 0.8 3.0 2.9 1.5 2.9 0.0 2.1 11.6 3.2 0.2 0.0 2.8 53.6 0.7 1.6 2.4 0.0 10.9 51.7 4.4 0.7 6.5 0.5 1.0 0.0 4.4 1.8 0.0 10.3 0.0 29.8 0.3 2.0 7.6 14.2 122.7 2.8 15.6 1.8 227.7 14.8 1.8 0.0 141.8 200.8 2.5 0.0 6.0 0.5 1.9 0.0 0.2 3.8 1.4 0.0 1.6 4.2 1.6 4.3 0.4 0.6 1.0 0.7 10.6 0.1 0.6 ARHGAP40 "C20orf95, dJ1100H13.4" ENSG00000124143 "Rho GTPase activating protein 40" Q5TG30 20 38601934-38651035 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "breast: 32.4;epididymis: 35.7;esophagus: 28.7;skin 1: 45.3" "Cell type enhanced" "Detected in some" "Breast glandular cells: 14.7;Breast myoepithelial cells: 8.6;Club cells: 4.3;Collecting duct cells: 3.7;Early spermatids: 7.2;Late spermatids: 4.3;Respiratory ciliated cells: 3.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.3;HBEC3-KT: 13.6;RPTEC TERT1: 11.7;SK-BR-3: 12.7;T-47d: 15.4" "Not detected" "Not detected" "HPA042636, HPA042840" Uncertain Supported "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" No NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA042636: AB_10962149, HPA042840: AB_10963929" "unprognostic (9.89e-3)" "unprognostic (2.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.24e-3)" "unprognostic (3.11e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-3)" "unprognostic (1.69e-1)" "unprognostic (3.09e-2)" "unprognostic (4.35e-2)" "unprognostic (5.63e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (2.89e-4)" "unprognostic (2.24e-1)" "unprognostic (7.42e-2)" "unprognostic (1.26e-1)" "unprognostic (1.54e-1)" 0.1 0.0 0.3 0.0 1.3 0.0 32.4 0.1 0.6 3.2 0.2 0.0 1.7 0.7 35.7 28.7 0.1 0.1 0.0 0.2 0.3 5.6 0.1 0.8 0.0 0.3 1.8 0.0 0.3 0.0 0.0 0.0 0.8 4.6 0.0 0.0 3.6 7.9 0.4 45.3 0.0 0.0 0.2 0.0 4.6 2.7 0.6 0.0 0.9 0.0 3.7 3.2 7.4 0.2 4.5 0.0 0.0 0.0 0.0 0.0 8.3 0.1 0.0 0.0 0.1 0.2 0.9 0.0 3.6 0.0 0.0 0.0 0.0 13.6 0.2 0.0 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.5 0.5 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 12.7 0.0 1.6 15.4 0.5 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.1 0.6 0.2 0.3 0.3 1.8 0.8 0.2 0.6 0.2 0.1 0.0 1.5 0.7 0.0 0.3 0.0 1.8 0.0 0.0 14.7 8.6 0.1 0.0 4.3 3.7 0.0 0.0 0.2 0.0 0.0 0.0 7.2 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.4 3.4 0.0 0.0 0.0 0.3 0.7 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 ARHGAP45 "HA-1, HMHA1, KIAA0223" ENSG00000180448 "Rho GTPase activating protein 45" Q92619 19 1065923-1086628 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 68.3;intestine: 53.2;lung: 39.5;lymphoid tissue: 106.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.1;Cytotrophoblasts: 40.1;dendritic cells: 62.7;Extravillous trophoblasts: 56.6;Hofbauer cells: 40.0;monocytes: 72.4;Syncytiotrophoblasts: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 73.7;Karpas-707: 100.4;RPMI-8226: 74.7;THP-1: 92.3;U-266/70: 130.8;U-937: 72.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019816, HPA079252" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA019816: AB_1853923, HPA079252: " "unprognostic (1.34e-1)" "unprognostic (5.13e-3)" "unprognostic (5.17e-3)" "prognostic favorable (6.02e-4)" "unprognostic (2.26e-1)" "prognostic favorable (7.82e-4)" "unprognostic (1.59e-2)" "unprognostic (2.17e-2)" "unprognostic (3.55e-1)" "unprognostic (4.78e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-2)" "unprognostic (1.00e-1)" "unprognostic (4.59e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (5.33e-2)" 11.2 5.5 3.6 43.1 3.4 68.3 5.5 4.4 7.5 4.2 5.1 12.4 7.2 3.5 0.5 5.5 6.7 5.0 4.4 3.3 4.4 7.8 7.4 39.5 58.4 9.1 5.4 2.0 2.7 0.8 4.5 6.0 6.9 5.9 2.6 8.7 6.4 1.5 2.1 3.9 53.2 2.2 7.6 106.1 10.9 3.5 8.1 32.9 9.0 0.8 18.6 6.6 5.5 11.4 11.2 2.1 0.1 12.1 0.0 0.0 27.8 0.1 0.0 0.0 0.0 29.2 13.9 73.7 3.0 0.0 0.4 9.6 2.1 0.6 0.0 54.7 1.0 10.1 22.6 3.5 0.4 48.6 56.2 0.0 2.9 0.1 0.0 0.0 0.1 46.8 6.8 100.4 0.0 0.6 54.5 43.4 7.6 1.9 5.4 52.0 0.3 74.7 0.0 0.2 0.6 0.2 16.8 0.0 4.5 0.7 3.5 92.3 4.8 0.2 1.9 0.2 0.3 130.8 60.2 58.8 0.3 72.1 5.4 6.7 24.4 25.3 45.7 21.2 38.8 15.9 52.2 54.1 22.5 18.3 68.9 53.6 37.0 28.0 20.9 13.3 43.5 59.8 3.6 3.4 4.4 7.5 3.3 4.4 9.1 5.4 6.9 7.6 8.1 11.4 2.0 48.1 8.4 0.0 17.8 0.0 0.0 0.0 0.0 0.0 15.2 11.0 0.0 0.0 1.8 11.0 0.0 40.1 62.7 0.0 0.0 2.6 0.0 4.5 0.7 1.6 0.0 0.0 0.0 3.8 56.6 1.3 0.0 3.5 3.8 0.2 0.0 0.0 40.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.0 0.0 72.4 0.0 0.0 0.0 0.0 7.8 0.0 0.0 15.2 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 75.5 30.2 0.1 0.0 0.0 ARHGEF1 "LBCL2, P115-RHOGEF, SUB1.5" ENSG00000076928 "Rho guanine nucleotide exchange factor 1" Q92888 19 41883173-41930150 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.4" "Cell type enhanced" "Detected in all" "dendritic cells: 156.2;NK-cells: 187.4;T-cells: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009502, HPA012924, HPA060784" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "CAB009502: AB_667785, HPA012924: AB_1845000, HPA060784: AB_2684363" "prognostic favorable (5.92e-4)" "unprognostic (2.09e-1)" "unprognostic (8.29e-3)" "unprognostic (8.10e-3)" "unprognostic (7.63e-2)" "unprognostic (7.59e-3)" "unprognostic (4.99e-2)" "unprognostic (7.28e-2)" "unprognostic (5.88e-2)" "unprognostic (1.84e-2)" "unprognostic (6.59e-2)" "unprognostic (3.29e-3)" "prognostic unfavorable (3.36e-8)" "unprognostic (3.54e-1)" "unprognostic (1.95e-1)" "unprognostic (8.00e-2)" "unprognostic (4.65e-2)" 50.2 20.9 17.1 79.1 21.8 113.5 39.9 19.1 21.9 37.2 17.8 37.5 26.8 33.4 3.6 34.1 36.4 23.5 26.2 16.1 18.2 31.9 30.0 67.7 127.5 24.1 20.2 32.9 27.4 12.6 25.9 18.3 22.0 32.1 10.4 5.6 28.8 11.8 15.4 37.6 87.1 13.4 19.0 168.4 34.9 10.9 21.4 96.5 36.7 8.9 48.9 33.9 33.2 27.9 58.8 69.9 15.8 19.9 21.9 22.9 18.4 30.1 45.7 37.4 32.8 21.5 49.2 77.9 54.6 27.8 19.8 33.8 20.3 46.9 11.8 74.1 23.6 63.1 30.6 28.4 31.9 68.4 100.8 27.8 30.5 36.3 23.5 19.9 36.2 68.2 25.5 46.7 21.8 40.4 48.0 52.9 17.9 46.4 54.0 71.8 29.7 46.3 23.2 31.8 10.3 43.8 42.3 18.7 36.0 8.1 21.9 114.4 49.6 49.7 33.2 26.8 47.7 63.0 43.2 68.4 40.5 107.6 80.2 10.4 20.5 29.2 47.0 39.5 37.2 20.1 35.6 49.4 21.5 19.5 36.1 39.4 27.4 32.1 57.5 11.3 38.7 36.4 17.1 21.8 19.1 21.9 16.1 18.2 24.1 20.2 22.0 19.0 21.4 27.9 46.6 6.4 22.0 35.3 97.3 14.5 13.9 15.0 20.5 18.7 13.1 12.4 4.2 8.6 8.8 7.3 27.1 13.3 156.2 21.7 3.9 23.6 1.4 12.2 16.7 29.0 21.7 23.8 8.0 24.9 22.8 17.7 56.6 16.8 31.7 19.3 26.7 9.3 38.2 11.8 7.9 29.2 16.2 52.5 31.9 1.8 19.3 58.9 19.6 18.7 39.0 8.8 187.4 13.6 27.6 55.9 22.7 16.6 66.4 15.7 10.1 7.3 6.3 19.1 26.3 17.6 17.3 7.3 10.1 17.3 14.8 10.1 159.0 20.4 26.4 11.1 ARHGEF11 "GTRAP48, KIAA0380, PDZ-RHOGEF" ENSG00000132694 "Rho guanine nucleotide exchange factor 11" O15085 1 156934840-157045742 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 68.6;Cone photoreceptor cells: 93.8;Excitatory neurons: 102.4;Inhibitory neurons: 122.5;Oligodendrocyte precursor cells: 78.4;Rod photoreceptor cells: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "WM-115: 69.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011026, HPA012037, HPA014658" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "HPA011026: AB_1850426, HPA012037: AB_1850430, HPA014658: AB_1850428" "unprognostic (2.19e-1)" "unprognostic (9.10e-2)" "unprognostic (1.91e-1)" "unprognostic (2.17e-1)" "unprognostic (2.00e-1)" "unprognostic (4.94e-3)" "unprognostic (3.30e-2)" "unprognostic (9.40e-2)" "unprognostic (1.21e-1)" "unprognostic (1.58e-1)" "prognostic favorable (1.72e-4)" "unprognostic (3.38e-1)" "unprognostic (2.41e-2)" "unprognostic (5.11e-2)" "unprognostic (1.58e-1)" "unprognostic (1.08e-1)" "unprognostic (4.73e-2)" 10.9 10.9 10.3 9.5 8.6 4.3 8.1 4.1 22.6 10.0 0.8 12.3 13.1 12.0 9.6 11.5 10.3 10.2 12.1 9.4 10.2 7.2 6.3 11.4 5.3 12.7 11.1 13.2 9.9 25.0 12.2 11.1 12.0 9.2 11.2 17.6 8.6 11.6 12.3 10.0 14.9 13.3 4.0 9.3 10.7 19.2 16.9 3.6 13.0 11.2 5.7 10.4 8.1 11.1 13.5 26.6 22.0 16.9 28.5 14.6 25.0 13.4 19.4 20.0 14.6 17.9 14.0 1.8 22.6 23.0 15.3 14.4 15.0 13.5 10.8 19.6 9.3 6.7 15.9 11.5 16.4 13.7 23.0 22.7 14.4 18.3 14.2 14.9 14.5 5.7 11.1 1.2 13.3 17.4 3.5 7.2 27.6 21.0 16.0 0.5 10.9 7.4 9.5 21.9 4.2 25.1 28.3 22.6 23.3 18.8 20.3 30.3 22.4 20.6 12.9 18.3 13.7 18.7 12.2 1.3 13.1 1.8 69.7 0.0 0.4 0.0 0.0 0.8 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.2 0.9 0.0 0.4 0.0 0.0 0.2 10.3 8.6 4.1 22.6 9.4 10.2 12.7 11.1 12.0 4.0 16.9 11.1 6.2 3.2 4.2 68.6 0.5 1.1 2.8 0.4 0.0 48.0 5.0 5.8 15.3 7.2 1.6 1.8 93.8 1.8 0.0 26.0 1.9 1.1 8.6 7.7 10.9 5.0 5.4 0.4 102.4 1.6 0.6 5.5 10.2 7.8 8.9 6.6 5.3 5.2 4.0 21.9 122.5 7.3 0.0 8.8 3.9 10.5 4.7 7.1 1.8 37.5 6.8 9.7 0.0 78.4 47.2 1.2 10.8 4.5 2.9 4.0 10.6 1.3 1.4 58.7 0.0 6.7 6.9 3.1 4.8 1.8 2.0 1.5 0.9 9.2 9.8 3.3 ARHGEF15 "ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF" ENSG00000198844 "Rho guanine nucleotide exchange factor 15" O94989 17 8310241-8322514 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 47.7;breast: 41.6" "Group enriched" "Detected in some" 4 "Adipocytes: 66.4;Endothelial cells: 48.9;Hepatic stellate cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "HUVEC TERT2: 40.4;TIME: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044443, HPA063495" Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA044443: AB_10960424, HPA063495: AB_2685023" "unprognostic (3.02e-1)" "unprognostic (2.97e-1)" "unprognostic (1.18e-2)" "unprognostic (7.09e-3)" "unprognostic (3.82e-1)" "unprognostic (7.29e-4)" "unprognostic (1.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (3.40e-1)" "unprognostic (1.06e-2)" "unprognostic (1.45e-1)" "unprognostic (2.23e-3)" "unprognostic (4.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.89e-1)" "unprognostic (9.56e-3)" 47.7 5.9 4.6 4.1 4.2 0.0 41.6 4.1 4.7 8.7 3.0 6.9 3.1 10.9 1.6 4.8 9.8 7.3 35.5 4.1 4.1 15.8 2.9 22.1 3.1 4.7 4.5 3.8 4.2 3.4 4.0 14.7 4.8 8.0 2.0 0.2 5.1 3.5 13.2 7.7 6.5 7.2 4.0 7.9 6.9 2.2 5.2 1.6 12.4 10.9 1.8 12.3 8.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 49.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.2 4.1 4.7 4.1 4.1 4.7 4.5 4.8 4.0 5.2 3.6 66.4 0.0 3.0 0.3 0.5 2.8 0.3 0.0 0.6 0.8 0.5 0.4 8.9 2.8 0.0 1.8 0.0 0.0 0.2 0.1 0.0 0.0 3.3 0.4 0.2 48.9 0.0 0.0 0.2 0.0 0.1 1.0 0.0 1.3 0.0 0.0 37.1 0.0 0.1 0.0 0.5 0.0 0.0 1.4 2.8 4.4 0.0 0.5 7.2 11.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.1 0.0 1.6 1.5 0.4 0.2 0.2 1.0 0.1 0.3 0.7 0.0 0.3 ARHGEF26 "DKFZP434D146, SGEF" ENSG00000114790 "Rho guanine nucleotide exchange factor 26" Q96DR7 3 154121003-154257827 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 339.7;Astrocytes: 248.8" "Cancer enhanced" "Detected in all" "prostate cancer: 19.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-251 MG: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017722, HPA049195" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017722: AB_1856800, HPA049195: AB_2680671" "unprognostic (1.41e-1)" "unprognostic (1.43e-3)" "unprognostic (3.55e-1)" "unprognostic (7.99e-3)" "unprognostic (2.82e-1)" "unprognostic (9.42e-3)" "prognostic favorable (9.74e-4)" "unprognostic (7.06e-2)" "unprognostic (1.16e-1)" "unprognostic (6.01e-5)" "unprognostic (1.44e-3)" "unprognostic (4.36e-2)" "unprognostic (2.22e-1)" "unprognostic (5.53e-3)" "unprognostic (3.11e-1)" "unprognostic (1.07e-1)" "unprognostic (5.24e-3)" 8.0 2.1 5.8 1.8 5.7 0.3 6.0 4.1 5.3 5.0 7.7 18.3 7.3 4.3 1.2 7.4 6.2 5.5 3.2 4.6 5.0 1.7 15.5 16.3 0.3 5.9 7.3 3.9 6.0 9.9 1.7 3.4 5.8 3.4 2.6 7.1 3.1 4.8 0.4 6.2 6.6 7.1 5.4 0.8 8.7 5.1 6.1 0.8 3.1 1.4 0.9 5.1 6.4 4.8 8.5 3.7 10.6 6.8 5.1 1.4 0.3 0.3 0.0 3.1 4.3 6.5 0.8 5.0 0.5 0.6 4.9 8.9 6.7 4.4 3.9 0.0 8.8 0.1 2.6 1.5 4.7 1.6 0.2 1.3 0.4 4.0 0.5 1.8 0.6 5.4 0.0 0.0 2.0 8.1 2.0 0.1 6.7 2.4 3.0 0.0 12.9 0.0 0.7 4.1 3.2 1.1 1.7 14.4 1.5 4.6 10.1 0.5 0.0 1.1 5.3 0.1 26.6 4.5 0.7 0.0 2.5 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 5.7 4.1 5.3 4.6 5.0 5.9 7.3 5.8 5.4 6.1 4.8 5.0 339.7 26.8 248.8 1.7 19.5 9.0 2.7 17.6 11.6 54.2 6.6 1.8 20.0 10.8 3.7 4.2 1.8 4.3 1.5 0.0 2.2 11.9 4.7 4.5 4.3 0.0 2.7 4.2 2.5 1.1 12.0 14.3 2.1 5.1 3.6 8.6 60.8 0.6 5.0 10.1 7.9 6.1 2.5 3.4 3.4 10.5 1.3 3.6 7.5 2.7 58.1 12.3 41.7 5.1 2.0 6.9 18.8 0.7 7.5 21.4 0.1 14.9 47.8 0.0 14.1 3.7 4.7 37.0 11.7 23.7 6.2 4.7 2.5 8.1 5.7 ARHGEF5 "GEF5, P60, TIM, TIM1" ENSG00000050327 "Rho guanine nucleotide exchange factor 5" Q12774 7 144355288-144380632 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 47.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 61.7;Glandular and luminal cells: 47.4;Paneth cells: 53.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 29.4;CAPAN-2: 21.9;HaCaT: 16.7;hTCEpi: 18.0;RPTEC TERT1: 17.5;WM-115: 17.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA020980, HPA029504, HPA044188, HPA045619, HPA045699" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "HPA020980: AB_1845007, HPA029504: AB_10602231, HPA044188: AB_2678850, HPA045619: AB_2679393, HPA045699: AB_2679423" "unprognostic (1.45e-1)" "unprognostic (2.05e-1)" "unprognostic (1.87e-2)" "unprognostic (1.94e-1)" "unprognostic (9.45e-2)" "unprognostic (2.69e-2)" "unprognostic (9.95e-3)" "unprognostic (9.21e-2)" "unprognostic (1.05e-2)" "unprognostic (2.27e-1)" "unprognostic (3.67e-2)" "unprognostic (2.12e-1)" "prognostic favorable (3.28e-7)" "unprognostic (4.67e-2)" "unprognostic (4.86e-1)" "unprognostic (2.36e-1)" "unprognostic (7.76e-2)" 5.1 2.6 1.8 1.6 2.4 2.4 12.3 1.5 1.7 11.5 5.7 16.4 10.1 3.4 6.9 36.6 4.7 4.7 3.5 0.9 1.8 20.9 14.4 8.4 2.2 2.1 2.7 5.6 19.0 7.3 9.5 3.2 1.8 14.7 5.6 1.8 18.1 2.0 0.7 47.1 13.1 1.2 1.3 3.8 13.8 2.0 2.0 1.8 24.0 0.2 3.1 5.3 17.6 1.4 29.4 3.3 0.0 0.0 0.0 0.0 8.7 3.8 2.3 1.5 1.9 11.5 21.9 0.1 10.3 0.9 0.3 16.7 0.0 10.6 1.5 0.1 3.8 0.0 4.2 0.8 3.1 0.0 0.0 5.5 18.0 0.7 9.9 4.8 0.1 0.0 0.0 0.0 1.5 9.7 0.1 0.0 4.5 7.9 5.2 1.1 0.0 0.4 17.5 1.3 0.1 0.1 11.5 13.4 5.1 2.3 6.8 0.3 0.2 0.5 0.8 0.0 0.1 0.0 0.1 0.1 0.6 0.0 17.7 0.0 0.0 0.0 0.3 0.0 0.4 0.8 0.8 0.7 0.0 0.9 0.9 0.2 0.3 0.0 0.0 0.0 1.5 0.1 1.8 2.4 1.5 1.7 0.9 1.8 2.1 2.7 1.8 1.3 2.0 1.4 3.0 6.4 14.8 0.3 2.3 18.5 37.3 9.4 26.2 0.0 17.5 18.7 1.4 11.5 12.1 22.0 4.2 11.8 1.4 61.7 5.9 14.8 2.3 28.9 5.5 1.6 9.6 2.7 0.0 16.5 15.2 3.6 37.2 47.4 0.0 4.0 1.8 7.5 1.8 0.0 0.0 24.0 6.1 0.3 1.9 0.6 1.5 1.2 5.4 0.0 0.0 2.7 0.0 0.5 0.1 27.7 53.7 1.5 3.1 14.3 42.0 5.4 13.5 3.1 0.0 1.1 1.8 0.7 1.5 28.7 16.8 14.2 2.5 1.1 23.5 33.6 ARL4C "ARL7, LAK" ENSG00000188042 "ADP ribosylation factor like GTPase 4C" P56559 2 234493041-234497081 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 74.0" "Cell type enhanced" "Detected in many" "dendritic cells: 610.9;Langerhans cells: 474.5;NK-cells: 437.7;T-cells: 349.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 149.4;RPTEC TERT1: 284.8;U-2197: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028927 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "HPA028927: AB_10602387" "unprognostic (1.93e-1)" "unprognostic (1.14e-1)" "unprognostic (3.20e-3)" "prognostic unfavorable (2.90e-7)" "unprognostic (8.01e-3)" "unprognostic (3.35e-2)" "unprognostic (9.26e-2)" "unprognostic (2.68e-2)" "unprognostic (2.10e-1)" "unprognostic (4.34e-2)" "unprognostic (3.17e-3)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.69e-8)" "unprognostic (8.57e-2)" "unprognostic (4.64e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (6.99e-5)" 15.1 10.6 15.4 31.7 14.6 65.0 17.3 17.8 18.6 11.4 45.3 9.1 6.6 5.8 9.5 23.2 11.9 31.8 5.1 13.1 21.9 12.2 12.8 16.1 55.3 21.9 17.1 2.1 5.5 10.8 7.4 16.5 21.3 10.3 11.2 9.7 21.6 5.4 1.5 24.1 13.2 5.9 12.8 51.0 13.6 1.2 18.5 74.0 3.7 1.7 32.1 25.5 18.0 13.8 32.3 97.4 12.0 1.6 10.4 3.0 31.6 3.2 13.8 3.8 6.6 45.4 60.4 0.1 8.0 7.7 109.0 23.5 12.0 66.4 4.1 30.4 4.2 0.0 0.6 0.6 10.7 0.1 2.8 6.4 42.2 36.6 21.2 149.4 6.4 78.4 0.4 102.4 16.4 4.4 93.7 0.3 12.6 22.5 21.9 0.3 54.1 18.0 284.8 35.2 44.1 8.1 1.1 7.1 4.7 18.2 0.9 1.9 14.8 60.0 23.2 168.2 61.6 51.1 19.7 1.6 101.9 0.1 32.0 79.8 1.2 27.4 86.7 1.6 85.6 18.1 60.0 69.5 10.3 18.3 53.5 59.1 2.2 61.2 0.9 55.2 83.8 30.0 15.4 14.6 17.8 18.6 13.1 21.9 21.9 17.1 21.3 12.8 18.5 13.8 12.3 73.7 15.9 8.8 63.6 124.8 120.7 18.4 145.1 156.6 40.4 64.6 10.9 67.2 27.0 14.7 8.4 30.0 610.9 2.3 0.0 19.6 7.8 73.9 19.2 23.4 1.8 6.1 15.5 5.7 5.4 23.7 19.9 186.3 27.8 1.1 11.0 3.4 31.4 107.7 103.0 2.5 0.0 208.4 474.5 6.5 0.3 182.1 42.7 6.5 41.8 32.2 437.7 6.0 2.5 16.5 0.1 0.0 132.6 60.4 0.1 0.9 4.7 13.1 0.0 7.0 19.3 0.7 1.9 65.4 42.9 14.6 349.8 0.4 1.2 46.6 ARRB2 "ARR2, BARR2, DKFZp686L0365" ENSG00000141480 "Arrestin beta 2" P32121 17 4710596-4721499 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 263.6;lymphoid tissue: 168.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 262.0;Kupffer cells: 242.5;Langerhans cells: 164.2;Macrophages: 226.4;monocytes: 311.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 195.8;HMC-1: 315.9;NB-4: 199.2;U-937: 279.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075177 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA075177: " "unprognostic (1.12e-1)" "prognostic favorable (2.93e-5)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" "unprognostic (7.43e-2)" "unprognostic (3.37e-2)" "unprognostic (2.62e-3)" "unprognostic (3.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.58e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (2.61e-5)" "unprognostic (1.32e-2)" "unprognostic (8.61e-2)" "unprognostic (4.92e-2)" "unprognostic (1.49e-1)" "unprognostic (1.88e-1)" 48.6 39.7 54.4 110.0 53.8 263.6 26.1 48.2 62.2 19.3 49.1 29.5 50.5 17.4 10.8 15.1 29.0 31.4 25.0 63.8 67.7 25.2 35.6 94.8 59.4 61.6 58.3 17.5 19.4 16.4 24.9 35.5 59.5 19.5 27.6 16.9 20.9 11.7 12.7 14.6 51.1 29.6 55.4 168.3 35.0 7.2 59.5 45.2 15.8 18.1 38.0 41.6 17.6 66.5 17.3 88.7 34.7 32.9 6.8 9.5 18.6 13.7 18.0 38.4 48.0 31.0 14.2 49.1 12.2 10.3 18.3 28.5 58.0 18.4 39.4 116.6 85.0 195.8 46.8 55.6 10.2 89.2 315.9 8.8 23.5 47.9 18.7 24.9 29.6 89.1 13.5 46.4 8.9 30.5 87.9 199.2 18.9 44.9 18.4 104.3 31.0 53.8 13.2 9.2 36.0 49.2 30.8 50.8 23.6 14.2 24.6 40.0 26.1 14.3 29.1 25.1 51.5 19.8 28.6 27.6 37.9 279.4 21.6 116.2 145.5 269.7 49.1 151.1 35.1 10.1 31.1 51.3 84.9 9.0 29.3 38.7 250.6 29.9 168.6 20.7 28.8 93.5 54.4 53.8 48.2 62.2 63.8 67.7 61.6 58.3 59.5 55.4 59.5 66.5 7.7 22.4 32.3 5.5 26.4 11.5 7.7 16.6 3.4 20.5 9.6 12.3 8.3 14.3 47.9 3.7 2.1 7.5 83.8 7.4 15.6 11.2 0.6 1.5 3.6 10.1 8.4 33.9 20.4 7.3 12.0 8.7 19.4 1.8 94.9 7.8 19.2 12.4 262.0 21.9 18.2 17.0 50.8 242.5 164.2 3.5 5.0 226.4 10.6 42.2 311.3 5.8 89.6 7.1 8.4 6.3 22.0 4.9 23.4 4.4 35.5 17.5 24.4 8.7 19.7 10.9 8.5 1.1 13.1 6.8 8.4 6.0 77.2 3.5 11.4 11.7 ARRDC4 FLJ36045 ENSG00000140450 "Arrestin domain containing 4" Q8NCT1 15 97960703-97973833 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 82.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 105.7;Paneth cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 1.1;classical monocyte: 2.5;eosinophil: 1.5;intermediate monocyte: 1.7;myeloid DC: 1.1;neutrophil: 1.4" "Group enriched" "Detected in many" 8 "dendritic cells: 1.1;granulocytes: 1.5;monocytes: 2.5" "Cell line enhanced" "Detected in many" "BJ: 103.2;HSkMC: 55.8;hTCEpi: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039934, HPA042109" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Vesicles "HPA039934: , HPA042109: AB_10795606" "unprognostic (2.13e-1)" "unprognostic (1.10e-1)" "unprognostic (2.32e-1)" "unprognostic (5.60e-3)" "unprognostic (4.49e-3)" "unprognostic (8.23e-2)" "unprognostic (1.16e-2)" "unprognostic (2.78e-1)" "unprognostic (7.65e-2)" "unprognostic (1.10e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (2.02e-3)" "unprognostic (2.90e-2)" "unprognostic (1.65e-1)" "unprognostic (3.04e-2)" "unprognostic (6.77e-2)" 12.5 12.2 21.6 16.5 24.6 11.5 19.8 24.1 22.4 16.2 16.9 43.9 15.8 14.6 15.6 10.0 14.5 17.2 12.1 30.5 39.1 25.1 30.2 19.8 7.5 76.6 24.1 7.3 34.7 6.3 8.9 18.3 73.9 10.9 23.0 4.5 8.1 16.4 14.8 35.5 22.6 18.1 45.9 8.0 26.9 14.7 20.5 5.7 17.3 9.6 5.1 14.9 10.8 82.8 5.8 0.2 0.8 15.0 6.6 47.7 0.0 103.2 45.8 13.5 6.0 6.2 3.6 0.0 14.2 4.8 1.2 6.0 3.7 36.0 21.6 0.0 9.6 10.1 1.9 4.1 2.6 7.0 15.2 55.8 86.9 15.4 17.9 18.8 0.7 2.9 14.4 0.0 4.9 19.2 1.2 5.8 3.0 17.4 2.1 0.1 0.9 0.2 26.3 12.7 5.0 8.8 15.7 5.7 29.5 3.1 2.1 10.6 0.1 4.0 2.9 21.2 5.0 0.0 0.0 0.2 8.7 1.2 10.6 1.1 2.5 1.5 0.0 1.7 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.4 21.6 24.6 24.1 22.4 30.5 39.1 76.6 24.1 73.9 45.9 20.5 82.8 5.7 3.2 10.4 19.9 4.0 25.4 3.1 11.0 23.9 1.6 14.4 8.3 12.9 8.6 9.4 22.0 6.2 0.3 1.4 105.7 7.9 2.7 4.5 21.5 17.6 5.9 38.3 4.4 8.1 8.2 0.2 12.3 15.8 18.0 23.5 1.4 6.4 17.1 21.5 0.0 6.0 29.5 10.2 23.9 10.5 10.9 5.0 19.7 24.9 3.7 13.4 0.7 3.1 38.7 3.4 12.0 82.4 8.2 0.2 12.2 30.2 3.1 15.6 3.5 0.0 7.8 12.5 2.0 12.6 11.8 31.1 0.7 1.3 17.5 31.3 12.2 ASGR2 CLEC4H2 ENSG00000161944 "Asialoglycoprotein receptor 2" P07307 17 7101322-7115700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "liver: 840.7" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 878.6" "Cancer enriched" "Detected in many" 66 "liver cancer: 214.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "classical monocyte: 110.0;myeloid DC: 64.1" "Group enriched" "Detected in many" 51 "dendritic cells: 64.1;monocytes: 110.0" "Cell line enriched" "Detected in some" 9 "Hep G2: 528.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014899, HPA015998" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA 14000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Plasma membrane" "HPA014899: AB_1845085, HPA015998: AB_1845084" "unprognostic (6.76e-2)" "unprognostic (7.45e-7)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (4.99e-2)" "unprognostic (1.16e-3)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (9.74e-2)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (9.35e-4)" "unprognostic (1.54e-3)" "unprognostic (6.95e-2)" "unprognostic (1.86e-1)" "unprognostic (7.31e-2)" 1.5 0.3 0.8 7.9 1.0 7.0 0.5 0.9 1.3 0.4 1.3 0.5 0.3 0.3 0.1 0.5 0.6 17.6 0.5 0.8 1.0 1.2 840.7 2.5 0.9 1.0 1.1 0.2 0.5 0.1 0.2 0.5 1.2 0.4 0.4 0.0 0.5 0.2 0.2 5.2 0.6 1.3 1.0 6.8 0.5 0.5 1.4 0.5 0.3 0.1 1.0 2.0 0.4 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 62.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 528.3 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.3 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 1.0 110.0 0.8 0.1 11.2 0.2 0.0 0.0 0.0 64.1 0.0 0.1 0.0 1.7 0.1 0.1 1.6 0.3 31.8 0.8 1.0 0.9 1.3 0.8 1.0 1.0 1.1 1.2 1.0 1.4 1.2 0.0 0.0 5.1 0.3 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 150.2 0.0 0.0 0.0 0.1 0.0 0.1 1.9 0.0 0.4 0.0 0.0 1.3 7.1 19.6 1.9 0.0 0.2 0.1 0.0 0.1 2.5 0.0 16.1 878.6 8.4 0.0 0.1 0.1 0.0 41.1 7.7 0.7 0.0 19.6 0.0 0.0 15.3 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 6.6 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.3 0.4 1.4 0.0 0.0 0.1 ASH2L "ASH2, ASH2L1, ASH2L2, Bre2" ENSG00000129691 "ASH2 like, histone lysine methyltransferase complex subunit" Q9UBL3 8 38105493-38144076 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 200.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042289 Approved Supported "Nucleoplasm,Plasma membrane" Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA042289: AB_10795608" "unprognostic (9.39e-2)" "unprognostic (5.58e-3)" "unprognostic (2.67e-3)" "unprognostic (5.40e-3)" "unprognostic (2.87e-1)" "unprognostic (2.66e-2)" "unprognostic (4.04e-1)" "unprognostic (9.15e-2)" "unprognostic (1.30e-1)" "unprognostic (1.12e-1)" "unprognostic (5.10e-2)" "unprognostic (9.73e-3)" "prognostic favorable (4.25e-4)" "unprognostic (9.95e-2)" "unprognostic (1.27e-1)" "unprognostic (7.69e-3)" "unprognostic (2.54e-1)" 28.9 18.9 19.7 17.9 20.3 31.6 21.4 19.2 21.5 19.9 14.7 22.5 18.2 22.0 17.1 23.8 20.1 17.4 21.3 20.2 17.4 23.3 23.6 18.5 27.9 16.7 16.1 26.2 17.7 24.8 12.0 22.1 16.7 19.9 22.3 21.7 20.6 21.0 32.4 20.4 18.3 24.2 16.5 18.9 22.1 41.3 19.0 33.6 21.1 27.7 28.3 18.5 16.1 18.1 45.6 23.3 39.8 39.8 26.3 34.0 49.8 44.1 45.7 53.5 47.0 24.9 21.1 51.4 38.2 37.1 27.2 27.5 49.0 24.8 50.4 20.3 22.4 200.3 22.9 51.7 39.4 32.0 41.3 28.6 22.9 25.0 27.7 28.1 43.9 48.0 138.2 40.0 53.7 26.1 91.9 40.7 51.7 39.3 15.6 38.2 42.9 23.4 28.9 33.1 18.3 32.4 33.5 22.5 38.4 37.1 27.4 40.4 33.5 35.3 35.0 50.4 37.6 37.8 48.7 44.9 35.2 44.7 49.7 39.9 23.0 55.9 16.8 26.8 18.1 19.6 18.8 20.0 27.7 19.2 19.3 18.4 19.2 26.1 25.8 15.8 21.3 21.6 19.7 20.3 19.2 21.5 20.2 17.4 16.7 16.1 16.7 16.5 19.0 18.1 11.1 12.8 15.8 18.3 14.3 6.9 9.3 13.3 10.8 12.9 9.6 8.0 18.1 8.6 15.9 12.9 10.4 37.0 15.9 11.5 7.9 21.2 10.8 12.7 13.2 14.0 10.8 62.1 19.7 28.7 37.2 17.3 8.6 10.8 19.6 38.2 12.8 11.9 24.2 6.7 21.4 11.6 12.2 17.2 5.7 13.0 23.3 17.0 23.2 15.9 29.2 17.8 19.6 17.6 16.5 21.3 8.9 20.7 8.4 6.2 12.8 17.1 18.0 15.5 13.1 14.6 20.7 69.6 33.9 11.6 6.8 30.9 11.9 37.3 10.9 7.4 ASIC1 "ACCN2, BNaC2, hBNaC2" ENSG00000110881 "Acid sensing ion channel subunit 1" P78348 12 50057548-50083611 "Predicted membrane proteins" "Calcium transport, Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.9" "Cell type enhanced" "Detected in some" "Astrocytes: 31.3;Inhibitory neurons: 16.4;Oligodendrocyte precursor cells: 64.8;Oligodendrocytes: 11.2" "Cancer enhanced" "Detected in many" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 34.8;SH-SY5Y: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058870 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus, Plasma membrane" "HPA058870: AB_2683841" "unprognostic (5.32e-3)" "unprognostic (1.70e-1)" "unprognostic (4.00e-2)" "unprognostic (3.56e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-3)" "unprognostic (2.92e-3)" "unprognostic (3.00e-2)" "unprognostic (1.72e-1)" "unprognostic (9.37e-2)" "unprognostic (2.34e-2)" "unprognostic (2.86e-3)" "unprognostic (6.97e-7)" "unprognostic (7.19e-2)" "unprognostic (3.73e-1)" "unprognostic (2.78e-3)" "unprognostic (8.27e-5)" 1.6 0.7 19.3 0.9 22.2 0.1 1.6 14.4 19.8 3.2 6.4 6.3 0.8 1.9 0.0 2.3 3.0 2.5 2.6 18.2 21.0 0.7 0.2 0.6 0.4 18.0 24.9 1.1 0.5 5.0 0.8 0.6 15.9 2.8 1.2 1.0 3.5 1.9 0.3 0.9 2.5 2.3 13.7 0.3 2.8 0.7 23.7 1.5 0.5 0.0 0.2 1.9 1.7 13.8 3.3 7.2 8.7 19.7 2.7 4.2 4.9 2.2 6.1 4.0 4.0 4.8 2.3 2.1 4.7 1.1 2.4 3.2 8.7 7.7 2.3 1.9 25.1 6.2 9.0 3.2 3.8 9.5 22.7 10.7 3.7 0.4 1.0 34.8 0.5 22.8 4.3 0.0 3.3 4.0 8.8 18.3 3.9 6.9 12.5 9.3 8.5 4.0 2.0 0.1 13.4 27.4 5.3 1.8 3.2 1.4 11.0 6.5 0.3 4.1 12.8 2.5 1.2 0.1 0.0 0.0 5.1 7.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 22.2 14.4 19.8 18.2 21.0 18.0 24.9 15.9 13.7 23.7 13.8 0.3 0.0 0.0 31.3 0.0 0.0 0.4 0.5 0.0 2.8 2.0 2.8 0.9 0.0 2.1 1.8 0.0 0.4 0.1 0.1 0.0 0.2 0.1 0.0 0.7 0.1 0.0 0.0 7.0 0.0 0.9 3.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 3.3 16.4 0.1 0.0 0.0 0.3 0.0 1.5 0.1 0.0 1.9 0.0 1.4 0.0 64.8 11.2 0.2 0.0 1.2 0.2 0.5 0.0 3.2 6.0 0.5 0.0 1.3 0.7 0.1 0.9 2.3 0.0 0.3 0.9 0.4 0.0 0.2 ATG3 "APG3L, DKFZp564M1178, FLJ22125, MGC15201, PC3-96" ENSG00000144848 "Autophagy related 3" Q9NT62 3 112532510-112562046 "Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 657.9;Spermatocytes: 341.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037260, HPA040471" Enhanced Supported "Plasma membrane,Cytosol" NA NA 140000 "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB037260: AB_1078236, HPA040471: AB_2677000" "unprognostic (2.77e-2)" "prognostic favorable (6.82e-4)" "unprognostic (4.90e-3)" "unprognostic (1.30e-1)" "unprognostic (2.63e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (9.35e-6)" "unprognostic (6.79e-2)" "unprognostic (6.67e-2)" "unprognostic (6.99e-2)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.52e-3)" "unprognostic (4.66e-2)" "unprognostic (6.02e-2)" "unprognostic (3.48e-2)" "unprognostic (5.25e-2)" 33.1 38.7 41.4 49.1 50.1 94.1 34.7 51.3 53.5 28.3 38.2 38.2 38.2 24.7 24.7 34.8 23.2 24.7 33.3 39.7 46.8 41.6 43.3 31.1 48.4 49.1 48.2 25.6 41.8 44.8 30.6 33.6 48.5 23.2 40.3 29.1 29.4 28.3 29.5 29.8 36.6 29.9 48.2 48.2 37.7 85.3 45.6 51.2 42.2 33.6 46.3 38.7 26.3 55.7 105.0 55.9 51.5 52.6 66.6 54.5 57.5 89.8 65.3 86.9 78.9 78.9 60.6 130.3 66.6 78.0 106.6 74.1 84.9 78.0 120.9 22.8 40.9 82.0 52.3 51.0 102.9 145.2 67.0 50.6 58.3 85.5 130.2 56.8 82.2 81.2 71.6 108.8 92.9 91.4 86.4 68.2 56.3 135.8 109.7 74.9 45.9 110.5 72.6 56.1 88.1 34.7 74.7 70.5 109.5 48.4 79.8 107.5 66.7 92.3 75.8 39.4 80.1 70.2 72.0 201.3 84.4 133.2 69.4 64.4 167.7 121.9 39.4 258.8 49.4 61.8 48.0 49.2 169.4 59.2 46.2 46.3 174.2 50.5 327.9 36.3 75.6 138.2 41.4 50.1 51.3 53.5 39.7 46.8 49.1 48.2 48.5 48.2 45.6 55.7 45.6 48.1 39.0 10.1 53.3 74.1 42.4 74.3 37.5 22.5 32.0 50.2 86.2 37.1 51.3 25.8 12.5 73.1 45.3 47.0 117.4 73.7 657.9 37.9 40.8 54.1 31.2 90.0 11.7 86.1 85.0 42.6 36.7 45.2 39.9 42.0 40.0 40.0 121.3 18.5 11.4 53.3 75.3 106.3 131.1 146.5 42.6 134.8 69.4 11.2 185.8 42.1 54.6 13.0 33.7 70.9 49.2 43.2 70.4 39.1 76.0 87.5 37.3 22.2 59.2 45.5 77.6 341.0 119.7 57.4 70.6 122.3 55.0 68.6 69.8 54.2 ATP10D "ATPVD, KIAA1487" ENSG00000145246 "ATPase phospholipid transporting 10D (putative)" Q9P241 4 47485275-47593486 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 176.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 12 "basophil: 84.3" "Lineage enriched" "Detected in all" 12 "granulocytes: 84.3" "Cell line enhanced" "Detected in many" "HAP1: 41.6" "Low region specificity" "Detected in all" HPA050808 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Plasma membrane" "HPA050808: AB_2681242" "unprognostic (1.62e-1)" "unprognostic (2.97e-1)" "unprognostic (4.93e-2)" "unprognostic (1.47e-2)" "unprognostic (1.16e-1)" "unprognostic (4.23e-2)" "unprognostic (1.65e-2)" "unprognostic (8.05e-2)" "unprognostic (3.48e-2)" "unprognostic (3.54e-2)" "unprognostic (3.04e-1)" "unprognostic (2.43e-1)" "prognostic favorable (5.00e-8)" "unprognostic (3.97e-2)" "unprognostic (4.47e-3)" "unprognostic (1.11e-2)" "unprognostic (3.37e-2)" 4.9 6.0 2.6 5.0 2.9 1.3 4.2 1.9 2.7 7.0 15.9 3.7 3.9 7.4 7.2 10.2 4.7 7.4 4.2 1.8 4.1 10.2 2.4 6.1 6.2 3.1 3.7 8.1 4.5 10.4 3.1 14.9 2.9 4.6 3.8 4.1 3.4 6.4 1.0 9.9 4.5 9.7 2.4 10.0 5.1 2.0 5.0 4.5 9.1 2.7 7.9 7.3 6.5 2.9 2.6 1.8 4.0 2.8 11.1 12.0 0.7 17.9 21.5 8.4 15.1 9.4 15.4 8.1 6.5 29.1 14.3 4.6 41.6 15.0 12.9 3.2 3.2 6.5 2.8 0.5 9.8 2.1 3.9 10.3 11.2 16.4 10.9 27.5 14.4 4.0 0.1 4.3 23.2 1.0 4.4 1.2 1.4 0.0 2.2 4.9 9.0 0.1 15.0 3.1 2.6 4.9 8.4 2.1 5.2 8.7 3.8 2.1 21.9 20.7 4.1 1.9 7.8 1.9 1.5 0.0 10.2 11.9 6.8 84.3 3.1 0.4 1.1 5.0 1.9 2.7 0.5 0.8 4.0 6.7 0.1 0.9 1.5 2.3 6.9 2.4 0.8 1.6 2.6 2.9 1.9 2.7 1.8 4.1 3.1 3.7 2.9 2.4 5.0 2.9 22.9 9.6 7.5 39.2 27.8 19.2 9.2 21.9 23.9 12.2 6.7 8.4 4.9 4.3 8.5 16.5 31.3 48.5 17.1 1.6 1.9 5.5 4.4 4.8 29.5 16.1 9.6 4.0 25.7 4.6 11.0 22.4 14.3 7.0 2.5 21.3 18.2 6.6 13.0 13.5 42.8 4.6 18.3 21.7 7.9 1.5 62.1 17.7 7.2 47.8 15.7 21.9 15.5 52.3 24.1 2.7 3.4 25.2 23.0 5.7 1.9 9.2 6.2 9.2 26.3 12.8 23.6 0.6 2.8 35.4 27.0 176.8 15.5 51.7 4.1 8.1 ATP12A "ATP1AL1, H-K-ATPase, HK" ENSG00000075673 "ATPase H+/K+ transporting non-gastric alpha2 subunit" P54707 13 24680408-24712472 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Sodium transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 11.2;kidney: 5.4;lymphoid tissue: 14.8;placenta: 5.6;skin 1: 6.2" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 75.6;Club cells: 49.2" "Cancer enhanced" "Detected in many" "testis cancer: 12.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "SuSa: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA039526 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Actin filaments" Cytosol "HPA039526: AB_10673534" "unprognostic (8.33e-3)" "unprognostic (3.58e-2)" "unprognostic (2.93e-1)" "unprognostic (5.21e-3)" "unprognostic (2.58e-1)" "unprognostic (1.21e-2)" "unprognostic (8.03e-3)" "unprognostic (2.64e-1)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.67e-1)" "unprognostic (6.80e-2)" "unprognostic (8.22e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.1 0.0 5.4 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.6 0.0 5.6 0.0 0.2 2.0 0.0 0.1 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 14.8 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 1.0 0.0 0.0 0.0 75.6 0.0 0.0 0.2 0.3 0.4 0.0 49.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 2.2 1.3 0.0 0.0 0.0 0.0 0.0 0.7 0.2 8.2 0.0 0.0 0.1 0.3 0.1 0.0 1.0 0.0 0.0 0.0 1.0 0.6 0.1 1.2 0.0 0.0 0.2 0.0 0.1 13.6 0.0 0.0 0.0 1.8 1.0 1.1 0.0 0.0 0.0 0.1 0.0 0.1 1.3 ATP1B3 "CD298, FLJ29027" ENSG00000069849 "ATPase Na+/K+ transporting subunit beta 3" P54709 3 141876124-141926549 "CD markers, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 982.6;Late spermatids: 930.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020697, HPA048963" Enhanced Supported "Plasma membrane" NA NA 33000 "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB020697: , HPA048963: AB_2680574" "unprognostic (2.31e-1)" "unprognostic (1.11e-3)" "unprognostic (2.75e-1)" "prognostic favorable (5.19e-5)" "unprognostic (2.60e-2)" "unprognostic (3.31e-2)" "prognostic unfavorable (6.32e-6)" "unprognostic (8.11e-3)" "unprognostic (6.99e-2)" "unprognostic (5.37e-3)" "unprognostic (1.48e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.29e-5)" "unprognostic (5.14e-2)" "unprognostic (2.04e-1)" "unprognostic (7.19e-3)" "unprognostic (6.15e-2)" 229.4 349.6 62.2 81.0 62.8 63.0 87.0 78.5 78.8 98.4 100.5 146.7 112.7 75.7 37.6 182.3 96.2 55.4 102.8 63.6 74.7 128.4 24.5 191.0 41.3 71.1 66.6 180.0 36.7 20.3 168.7 96.7 76.5 102.0 168.0 43.6 85.8 46.2 26.7 259.3 125.0 71.4 68.7 65.7 66.3 75.8 70.6 51.4 75.8 16.0 57.1 101.0 161.2 62.2 280.8 170.1 155.5 145.6 411.7 118.0 354.7 322.2 287.6 224.2 252.1 253.7 136.5 223.3 278.2 243.5 328.4 595.8 157.0 152.2 253.4 120.4 190.0 195.7 161.4 156.8 161.7 164.9 149.1 126.5 355.1 179.1 169.7 162.4 245.7 156.3 135.9 193.7 233.8 114.6 165.6 275.0 213.6 384.5 76.1 225.0 116.4 227.1 191.1 186.7 127.6 86.0 413.2 188.5 455.9 270.7 145.6 197.2 170.7 196.4 76.3 298.8 189.8 138.0 197.6 367.5 259.5 176.5 165.2 69.7 104.1 35.4 70.4 174.3 51.7 39.7 56.3 74.8 103.3 30.4 32.6 59.6 6.7 32.0 260.4 64.8 68.4 103.7 62.2 62.8 78.5 78.8 63.6 74.7 71.1 66.6 76.5 68.7 70.6 62.2 114.7 57.7 41.9 38.2 143.4 492.8 428.3 535.9 326.7 35.9 53.0 46.4 19.7 17.2 177.6 220.7 25.0 281.3 464.5 982.6 41.1 73.9 465.9 86.0 72.2 199.2 56.1 147.1 107.5 60.6 226.8 164.1 24.5 127.2 130.7 94.3 100.6 9.0 305.9 25.2 91.2 65.2 164.8 148.0 678.3 930.5 84.8 455.3 222.3 37.5 364.8 46.3 75.2 46.3 54.7 70.6 321.1 68.4 153.1 396.5 413.3 41.5 33.3 28.4 124.9 99.5 265.2 69.0 200.2 178.4 414.4 391.4 216.1 122.2 134.9 370.2 ATP2B1 PMCA1 ENSG00000070961 "ATPase plasma membrane Ca2+ transporting 1" P20020 12 89588049-89709300 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 106.8" "Cell type enhanced" "Detected in all" "Excitatory neurons: 781.6;Langerhans cells: 435.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 314.6;LHCN-M2: 501.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005605, HPA011166, HPA012945" Enhanced Supported Supported "Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB005605: AB_2061563, HPA011166: AB_1855484, HPA012945: AB_1855483" "unprognostic (6.78e-2)" "unprognostic (5.27e-2)" "unprognostic (1.57e-2)" "unprognostic (8.23e-2)" "unprognostic (1.72e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (7.74e-4)" "unprognostic (2.77e-2)" "unprognostic (2.46e-2)" "unprognostic (7.82e-2)" "unprognostic (5.98e-2)" "unprognostic (2.68e-1)" "unprognostic (4.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-2)" 18.5 11.2 33.0 25.6 92.0 106.8 19.6 14.0 59.1 18.8 0.0 33.1 40.8 18.2 12.1 14.7 18.6 25.2 11.0 52.7 4.9 16.4 22.7 21.3 29.2 0.0 14.4 13.1 17.1 21.5 11.0 27.3 0.0 13.9 32.3 71.2 11.5 14.9 24.4 26.0 30.1 19.7 0.0 30.7 29.0 23.0 10.9 18.4 14.4 24.1 28.8 37.0 10.6 34.9 24.0 117.8 45.5 22.1 64.5 102.2 20.9 71.2 232.6 67.5 106.8 47.7 21.6 46.8 4.9 99.3 77.6 21.0 40.3 19.7 187.5 16.2 46.9 16.6 39.8 41.9 209.6 70.7 26.6 85.0 36.9 210.8 314.6 78.9 17.5 17.6 27.9 16.6 501.1 37.6 22.1 30.1 35.6 32.9 55.6 31.1 146.4 19.7 64.4 108.5 42.9 23.4 82.6 22.9 20.2 91.7 33.9 7.8 12.5 181.8 29.4 67.6 78.9 12.7 21.2 49.1 82.6 19.6 41.0 9.4 39.4 22.3 20.9 42.5 26.4 84.5 36.3 26.8 51.3 84.4 13.2 16.8 127.1 27.0 86.1 9.0 53.7 21.8 33.0 92.0 14.0 59.1 52.7 4.9 0.0 14.4 0.0 0.0 10.9 34.9 46.0 44.8 46.0 90.8 226.4 201.6 71.0 29.3 76.2 370.9 30.9 109.7 20.3 45.8 30.0 53.3 154.3 176.8 139.8 181.5 1.9 27.6 2.3 29.3 61.0 63.6 91.6 31.5 781.6 28.5 42.1 91.6 44.9 59.4 31.6 45.5 49.6 39.5 193.5 302.9 279.1 30.7 16.2 116.0 435.1 9.6 29.2 285.4 55.2 126.5 157.1 96.4 50.4 193.5 91.9 25.5 80.6 32.0 133.9 54.7 75.0 22.1 20.6 113.3 32.9 97.0 69.5 44.5 130.7 30.4 204.7 228.8 125.1 76.0 65.9 90.2 ATP2B4 "ATP2B2, MXRA1, PMCA4" ENSG00000058668 "ATPase plasma membrane Ca2+ transporting 4" P23634 1 203626787-203744081 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 175.3" "Cell type enhanced" "Detected in many" "Adipocytes: 171.6;Oligodendrocyte precursor cells: 199.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ: 200.0;BJ hTERT+: 276.4;fHDF/TERT166: 212.8;SuSa: 222.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016118, HPA040431" Enhanced Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB016118: AB_2061729, HPA040431: AB_2676980" "unprognostic (7.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.60e-2)" "unprognostic (8.17e-2)" "unprognostic (2.53e-2)" "unprognostic (9.23e-3)" "unprognostic (8.68e-2)" "unprognostic (3.81e-2)" "unprognostic (9.74e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (3.52e-3)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-3)" 58.9 25.0 39.7 25.6 36.3 16.0 16.6 0.0 33.5 47.5 0.3 58.2 12.5 104.5 20.1 32.5 48.4 25.2 59.5 40.2 13.3 9.9 9.3 35.1 12.8 8.0 8.0 40.6 9.9 11.8 3.8 40.6 11.2 33.0 30.2 42.5 7.1 69.7 14.4 54.8 14.4 175.3 0.2 12.2 15.4 27.4 44.7 21.7 15.1 27.7 19.4 37.2 15.3 2.6 45.7 7.8 15.6 15.1 120.4 175.1 84.5 200.0 276.4 32.1 27.4 3.8 22.8 9.8 28.8 212.8 43.5 43.5 22.6 27.7 34.3 126.5 8.0 28.7 37.4 2.5 43.1 42.0 51.3 130.5 26.9 102.9 16.2 81.6 63.5 57.1 12.9 20.3 25.1 2.5 44.3 14.5 9.7 8.7 24.2 22.3 11.6 16.7 11.3 4.0 4.6 6.7 68.3 10.5 30.2 222.1 9.3 21.4 54.9 80.5 11.4 136.6 48.3 13.4 20.9 5.4 80.7 31.0 24.5 3.2 2.0 0.0 8.7 1.3 6.4 0.9 5.4 7.2 2.2 0.3 1.3 3.4 4.0 3.8 2.2 3.7 5.7 2.7 39.7 36.3 0.0 33.5 40.2 13.3 8.0 8.0 11.2 0.2 44.7 2.6 171.6 89.8 68.2 127.6 9.9 97.1 18.9 43.1 41.5 4.8 11.2 9.4 76.5 7.2 35.0 18.4 2.1 27.9 56.2 2.2 0.0 35.3 5.8 78.0 92.4 67.6 23.9 35.9 55.9 14.9 18.9 56.0 13.7 89.7 10.1 30.6 58.9 18.2 38.5 117.8 9.8 2.4 14.2 14.7 38.8 4.8 43.8 20.4 26.6 37.5 18.1 136.1 66.9 199.0 40.4 31.4 11.1 38.0 27.6 48.2 7.2 3.3 39.7 7.8 19.7 50.7 81.2 21.7 2.8 54.7 150.9 26.0 59.7 8.0 3.3 62.0 ATP6V0A2 "a2, ATP6a2, ATP6N1D, J6B7, Stv1, TJ6, TJ6M, TJ6s, Vph1" ENSG00000185344 "ATPase H+ transporting V0 subunit a2" Q9Y487 12 123712353-123761755 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 51.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044279 Approved Supported "Vesicles,Plasma membrane,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Vesicles, Focal adhesion sites" "HPA044279: AB_10961274" "unprognostic (2.60e-1)" "unprognostic (8.79e-3)" "unprognostic (3.60e-2)" "unprognostic (1.50e-1)" "unprognostic (2.70e-1)" "unprognostic (2.29e-2)" "unprognostic (2.06e-4)" "unprognostic (1.40e-1)" "unprognostic (3.77e-2)" "unprognostic (1.75e-1)" "unprognostic (8.85e-3)" "unprognostic (1.63e-1)" "unprognostic (1.26e-1)" "unprognostic (7.48e-2)" "unprognostic (1.12e-1)" "unprognostic (3.47e-1)" "unprognostic (1.58e-1)" 6.6 4.4 5.6 7.0 6.2 10.4 5.7 7.4 6.5 4.7 6.9 5.5 8.7 6.0 3.9 4.3 4.8 3.8 4.7 6.0 6.0 3.8 4.2 6.3 8.3 6.6 5.8 4.1 5.7 3.7 4.9 3.7 6.5 4.7 5.8 6.7 7.6 4.0 6.5 9.4 7.0 5.1 5.6 6.6 8.8 4.9 6.2 7.5 4.8 3.5 8.2 5.3 4.5 7.9 4.8 10.3 12.0 17.8 9.2 7.0 6.7 6.2 6.2 5.4 5.8 6.9 2.7 18.0 4.2 7.6 5.5 9.0 16.1 6.2 4.5 11.4 10.2 27.9 9.2 5.4 10.2 16.8 51.0 6.7 4.4 5.9 7.4 9.0 5.0 15.0 14.5 3.4 8.1 8.4 15.4 24.8 11.5 6.6 6.5 15.7 9.9 6.4 8.3 10.4 7.2 13.6 9.3 6.9 9.4 6.6 5.9 14.4 8.3 8.0 3.1 10.8 9.1 10.8 12.8 14.9 9.4 12.1 6.5 6.3 0.7 13.7 1.7 0.9 1.0 0.9 1.7 1.5 0.8 3.7 1.6 1.8 2.0 1.7 1.5 2.8 1.0 0.8 5.6 6.2 7.4 6.5 6.0 6.0 6.6 5.8 6.5 5.6 6.2 7.9 13.0 6.4 11.0 3.9 20.4 10.1 10.8 4.6 11.4 20.5 7.9 5.3 8.8 12.8 8.3 9.2 12.5 5.2 27.9 17.9 0.0 8.1 10.2 11.0 11.9 10.6 13.2 50.3 21.2 10.9 5.7 11.3 18.3 12.3 75.3 8.7 18.2 11.4 8.4 11.8 19.3 9.8 2.0 9.4 17.2 4.5 8.7 11.3 1.8 7.5 13.2 9.0 25.7 10.6 17.1 9.2 9.0 9.4 19.7 15.7 11.1 4.0 13.5 28.8 6.6 12.4 10.9 23.6 12.6 9.6 14.2 6.8 21.8 5.7 11.4 11.4 ATP8A2 "ATPIB, ML-1" ENSG00000132932 "ATPase phospholipid transporting 8A2" Q9NTI2 13 25371974-26025851 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 21.6;pituitary gland: 15.2;retina: 17.2" "Group enriched" "Detected in many" 6 "Excitatory neurons: 518.7;Inhibitory neurons: 727.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 19.9;JURKAT: 9.8;MOLT-4: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039926, HPA040033" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "HPA039926: AB_10794205, HPA040033: AB_2676809" "unprognostic (3.79e-2)" "unprognostic (4.28e-2)" "unprognostic (3.32e-2)" "unprognostic (1.95e-4)" "unprognostic (3.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.31e-2)" "unprognostic (2.97e-3)" "unprognostic (2.77e-1)" "unprognostic (3.66e-1)" "unprognostic (4.96e-4)" "unprognostic (1.24e-1)" "unprognostic (1.18e-2)" "unprognostic (4.20e-5)" "unprognostic (9.10e-2)" "unprognostic (2.95e-1)" "unprognostic (7.22e-2)" 0.1 2.1 5.5 0.3 6.7 0.0 0.6 8.0 21.6 0.2 0.0 0.4 0.3 0.6 1.8 0.0 0.0 0.1 0.1 8.7 19.3 0.3 0.0 0.8 0.6 12.8 4.6 0.2 0.6 0.0 15.2 0.2 12.1 0.1 0.2 17.2 0.1 0.0 0.3 0.1 0.3 0.1 0.2 0.3 0.6 2.9 6.6 1.0 0.1 0.1 0.2 0.2 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 19.9 0.1 0.0 0.0 0.0 0.6 0.5 9.8 0.0 0.0 1.7 0.1 3.9 0.0 2.0 0.0 0.7 0.0 2.7 0.9 0.2 0.0 3.2 0.0 0.2 0.2 0.1 0.2 0.0 0.4 0.2 0.0 1.0 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.2 0.1 5.5 6.7 8.0 21.6 8.7 19.3 12.8 4.6 12.1 0.2 6.6 6.8 0.7 0.0 12.2 9.4 0.8 1.0 0.2 0.3 0.0 21.5 1.5 0.3 2.5 1.5 0.4 0.0 95.9 1.5 0.4 0.0 0.0 0.3 39.0 1.2 23.6 2.6 0.0 0.8 518.7 0.0 0.4 1.7 1.1 0.9 5.1 3.7 0.0 0.0 3.2 21.9 727.7 0.0 0.0 0.0 0.7 30.3 0.9 0.3 0.0 9.4 0.0 7.2 1.0 88.4 24.7 0.0 0.0 1.2 0.1 0.2 0.0 1.3 0.3 91.6 13.1 0.3 0.8 19.8 12.5 0.0 0.4 1.1 1.8 10.1 0.1 0.1 ATP8B1 "ATPIC, BRIC, FIC1, PFIC, PFIC1" ENSG00000081923 "ATPase phospholipid transporting 8B1" O43520 18 57646426-57803315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 279.7;Intestinal goblet cells: 180.5;Paneth cells: 116.7;Undifferentiated cells: 185.7;Urothelial cells: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 90.2;RT4: 168.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018673, HPA018674" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA018673: AB_1845207, HPA018674: AB_1845208" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "prognostic favorable (2.60e-4)" "unprognostic (8.81e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-1)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (9.62e-3)" "unprognostic (1.97e-1)" "unprognostic (3.30e-3)" "unprognostic (4.55e-3)" "prognostic favorable (6.35e-4)" "unprognostic (1.88e-1)" "unprognostic (2.22e-1)" "unprognostic (3.25e-1)" "unprognostic (8.60e-3)" 9.1 5.4 1.3 8.5 2.0 1.2 9.5 3.6 3.9 16.3 3.0 76.2 30.3 5.9 3.5 14.8 10.6 18.0 4.4 1.7 1.1 6.6 7.7 8.3 2.2 2.1 1.1 2.1 23.3 9.7 2.7 6.9 2.0 17.6 61.7 0.6 20.6 11.5 1.9 8.4 38.2 8.3 1.0 4.6 46.1 0.6 1.9 1.5 22.0 1.8 3.6 30.0 13.0 3.0 32.0 10.7 0.1 0.6 10.5 19.2 11.9 62.6 63.6 67.4 40.4 8.0 24.3 1.5 19.3 90.2 22.3 44.9 0.2 13.9 64.3 0.2 1.1 0.2 2.6 2.5 2.2 0.4 0.6 2.9 12.6 20.8 34.0 39.5 33.0 0.3 0.3 0.7 34.1 15.6 0.1 0.3 0.3 35.5 3.3 0.3 0.2 0.0 7.9 168.1 0.8 0.7 1.3 32.5 0.1 0.5 10.3 0.6 35.3 48.3 2.0 7.7 14.2 0.4 0.4 0.5 1.1 0.4 2.8 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.4 0.1 0.2 0.6 0.0 0.2 0.1 0.0 0.0 1.3 2.0 3.6 3.9 1.7 1.1 2.1 1.1 2.0 1.0 1.9 3.0 25.9 19.2 27.0 11.1 4.1 7.8 66.7 20.6 10.2 0.7 28.4 10.4 5.4 27.1 48.9 40.5 0.0 25.6 0.6 279.7 0.0 27.0 2.8 26.3 4.0 30.8 68.4 0.4 61.2 53.1 2.7 7.1 98.4 40.1 4.5 0.9 33.2 19.1 2.4 6.7 11.7 180.5 22.4 2.8 4.0 0.4 0.3 1.0 7.2 37.5 0.9 0.1 0.0 20.6 10.7 38.5 116.7 0.0 0.9 70.8 58.2 0.2 44.7 1.2 13.1 2.8 20.7 0.3 1.5 28.0 16.3 10.9 1.7 2.3 185.7 119.2 ATP8B2 "ATPID, KIAA1137" ENSG00000143515 "ATPase phospholipid transporting 8B2" P98198 1 154325525-154351304 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 26.8;Excitatory neurons: 28.5;Inhibitory neurons: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 2.8;T-cells: 3.7" "Cell line enhanced" "Detected in many" "ASC diff: 120.9;fHDF/TERT166: 112.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046680, HPA061103" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" "Nucleoli, Cytosol" "HPA046680: AB_2679749, HPA061103: " "unprognostic (1.68e-1)" "unprognostic (3.68e-1)" "unprognostic (8.40e-2)" "unprognostic (5.16e-2)" "unprognostic (4.52e-1)" "unprognostic (8.17e-2)" "unprognostic (2.27e-2)" "unprognostic (6.93e-3)" "unprognostic (2.57e-1)" "unprognostic (1.69e-1)" "prognostic favorable (1.60e-4)" "unprognostic (2.82e-1)" "unprognostic (1.89e-3)" "unprognostic (7.77e-3)" "unprognostic (6.58e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (5.29e-5)" 17.2 9.5 8.2 22.7 7.8 5.4 14.0 18.8 11.0 28.7 20.7 17.8 12.5 39.2 17.7 11.0 30.8 18.2 15.2 10.8 9.2 6.3 3.4 18.0 25.4 8.9 8.1 35.3 5.9 10.5 19.3 15.3 9.6 18.9 9.1 2.1 7.2 21.2 3.5 8.5 17.6 39.7 5.6 19.5 14.5 16.3 8.8 18.4 15.0 7.4 19.6 19.7 17.9 7.7 2.1 15.6 20.0 20.5 120.9 80.4 0.3 41.8 77.4 26.1 30.5 0.3 0.6 1.9 21.4 112.4 17.7 9.2 23.0 5.5 19.3 46.6 16.8 19.7 20.4 18.9 37.2 0.1 14.8 53.4 1.3 40.6 38.7 35.6 40.0 25.1 37.6 47.8 22.7 21.8 36.2 2.5 43.7 0.4 17.4 39.9 12.7 71.5 5.3 0.4 17.4 22.7 11.3 2.8 30.3 28.3 14.9 15.3 34.7 40.2 19.2 51.4 13.5 58.0 75.7 11.1 14.1 2.2 24.7 2.8 0.0 1.7 1.1 0.0 0.7 0.3 1.7 1.9 0.0 0.2 1.4 1.2 0.0 0.5 0.0 0.3 3.7 0.5 8.2 7.8 18.8 11.0 10.8 9.2 8.9 8.1 9.6 5.6 8.8 7.7 6.4 3.2 4.5 26.8 7.7 2.5 1.4 0.9 0.0 4.5 1.9 2.3 6.2 0.0 1.9 0.0 2.1 0.1 16.0 0.1 0.0 1.6 0.6 6.5 20.5 9.0 0.0 0.4 28.5 0.2 0.5 12.8 0.5 2.4 7.6 10.8 13.6 0.8 0.4 8.4 31.7 0.2 0.0 1.0 4.2 1.4 11.5 1.3 7.2 4.7 0.9 3.4 7.2 4.0 4.2 0.9 0.0 14.7 13.9 5.6 0.0 0.2 4.4 0.5 0.0 9.5 11.2 2.6 4.3 0.6 1.6 0.3 17.2 6.7 0.1 0.8 AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219223-41261766 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 147.2;Kupffer cells: 187.5;Langerhans cells: 185.5;Prostatic glandular cells: 123.4;Sertoli cells: 210.4;Smooth muscle cells: 171.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 11.1;plasmacytoid DC: 25.7" "Group enriched" "Detected in many" 12 "dendritic cells: 25.7;NK-cells: 11.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 501.2;U-251 MG: 540.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" NA Yes 12100000 72000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: AB_2675470, HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" 43.6 18.8 17.5 15.5 22.6 1.7 26.6 19.7 17.7 36.1 12.4 42.5 11.7 34.4 8.7 17.6 25.4 22.4 26.7 16.6 18.8 9.8 15.0 25.9 6.2 26.8 20.6 24.7 6.3 10.7 7.3 34.2 22.1 19.2 12.6 5.8 10.6 24.6 9.4 20.0 19.0 37.1 20.9 37.7 21.4 18.6 24.0 7.2 16.6 11.3 5.0 32.5 25.2 21.9 408.0 160.0 9.7 1.3 34.6 34.7 0.5 314.5 280.2 450.9 278.2 8.5 185.5 0.2 124.7 501.2 235.3 33.3 0.4 211.8 384.8 0.7 0.3 0.0 100.4 6.3 125.0 0.3 0.3 26.4 3.8 266.7 409.5 254.8 169.8 0.1 15.8 0.5 284.6 0.5 0.2 0.4 4.1 1.0 76.3 0.2 165.3 0.3 202.3 0.2 0.1 0.1 81.5 0.6 1.8 57.4 0.9 7.2 351.8 317.8 214.6 307.7 540.8 0.5 0.9 1.0 211.5 0.5 241.8 1.5 0.3 0.2 0.1 0.4 0.2 0.1 0.3 0.1 6.0 0.1 0.3 0.3 0.3 11.1 0.2 25.7 0.4 0.3 17.5 22.6 19.7 17.7 16.6 18.8 26.8 20.6 22.1 20.9 24.0 21.9 13.5 9.6 3.6 35.9 1.9 41.7 88.3 10.3 3.4 0.5 2.3 14.2 8.6 1.5 4.4 5.5 0.0 4.2 0.8 0.1 0.0 6.9 8.7 6.0 45.8 17.7 0.0 0.0 0.8 0.2 2.1 147.2 1.5 5.4 0.0 17.3 11.0 1.2 28.8 1.7 1.1 0.1 2.0 187.5 185.5 5.5 61.5 61.4 26.6 30.9 3.1 26.8 0.0 11.1 0.5 14.5 0.1 79.7 0.8 123.4 0.3 0.1 2.8 1.2 210.4 38.1 171.1 1.9 2.0 1.2 29.1 11.5 3.6 2.5 0.1 28.0 BACE1 BACE ENSG00000186318 "Beta-secretase 1" P56817 11 117285207-117316259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 119.1;pancreas: 271.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 118.9;Early spermatids: 99.9;Late spermatids: 343.0;Oligodendrocytes: 99.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 88.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016358 Approved Supported "Plasma membrane" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "CAB016358: AB_626716" "unprognostic (7.96e-3)" "unprognostic (8.05e-2)" "unprognostic (3.55e-2)" "unprognostic (3.05e-3)" "unprognostic (8.94e-2)" "unprognostic (3.39e-1)" "unprognostic (1.03e-1)" "unprognostic (2.60e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (8.09e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.35e-2)" "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.76e-4)" 15.4 16.0 34.3 8.0 68.5 3.3 11.7 68.7 44.0 18.3 11.9 13.7 6.1 19.7 8.8 13.5 15.9 19.1 11.4 34.3 44.5 14.8 25.6 14.4 5.1 89.7 67.0 20.5 271.5 18.5 10.7 13.8 76.6 13.4 7.6 44.7 11.0 18.3 12.5 11.4 7.7 21.3 61.6 12.4 9.8 11.2 59.9 3.8 12.2 9.1 5.0 12.4 14.3 119.1 11.5 10.7 22.9 37.3 80.9 82.3 1.0 62.9 44.4 24.4 19.0 4.5 16.4 1.4 14.6 88.3 18.4 17.9 24.3 12.1 20.5 3.1 12.1 6.0 17.3 5.1 36.5 2.5 1.7 68.1 20.2 29.7 31.8 68.0 21.4 3.8 2.7 1.1 46.5 33.4 2.5 2.1 15.5 10.6 25.9 6.4 11.6 1.6 12.2 5.9 31.7 36.7 22.5 2.6 5.9 23.5 26.2 7.6 31.4 45.2 5.0 48.2 19.4 0.7 1.0 1.1 23.8 2.0 34.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 34.3 68.5 68.7 44.0 34.3 44.5 89.7 67.0 76.6 61.6 59.9 119.1 12.1 19.2 10.1 16.3 0.3 4.7 4.1 3.4 9.1 53.7 8.7 9.0 8.7 18.6 13.3 5.5 118.9 1.0 0.1 2.0 5.9 7.4 99.9 5.1 32.1 8.3 21.7 1.7 24.9 20.0 1.3 19.5 3.1 8.9 2.5 15.8 6.8 38.6 9.4 57.2 32.0 5.1 2.0 17.2 7.7 343.0 19.3 7.9 3.6 14.0 4.0 17.9 0.0 22.1 99.8 4.3 6.3 22.2 0.1 2.4 1.7 6.3 3.4 55.2 6.6 18.1 14.2 3.4 1.7 10.6 3.4 0.8 1.2 68.0 4.5 3.4 BDKRB2 BK-2 ENSG00000168398 "Bradykinin receptor B2" P30411 14 96204679-96244166 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 41.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.3;Endothelial cells: 18.2;Fibroblasts: 25.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 49.2;BJ hTERT+: 94.5;U-87 MG: 39.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA003551, HPA050841" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA003551: , HPA050841: AB_2681254" "unprognostic (1.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (8.79e-3)" "unprognostic (2.68e-2)" "unprognostic (1.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.84e-2)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-3)" "unprognostic (3.11e-2)" "unprognostic (9.40e-2)" "unprognostic (9.90e-2)" "unprognostic (1.49e-2)" 14.0 1.4 0.8 5.5 1.0 0.0 5.8 3.8 1.1 15.6 0.9 12.4 7.9 6.7 2.4 17.2 7.2 20.8 1.2 0.9 0.8 13.4 0.7 2.5 0.3 4.9 1.3 1.0 9.4 0.9 0.8 1.3 5.0 4.8 12.2 0.0 3.5 6.2 0.9 5.4 9.7 10.2 1.0 0.1 4.9 0.2 1.5 0.9 3.6 1.8 1.7 41.1 15.4 1.2 1.7 6.1 0.1 11.0 16.2 49.2 0.0 5.5 94.5 3.2 3.7 0.3 10.4 0.0 0.2 8.7 3.7 14.8 0.0 2.4 2.8 1.2 0.1 0.0 1.1 0.0 7.8 0.0 0.0 15.1 7.5 9.4 4.7 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.1 0.1 20.4 0.0 0.0 2.2 0.0 3.2 0.0 3.4 1.1 1.8 15.6 0.1 2.1 1.0 0.0 0.0 0.3 0.3 3.3 0.1 0.2 0.0 0.0 39.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 1.0 3.8 1.1 0.9 0.8 4.9 1.3 5.0 1.0 1.5 1.2 8.2 3.2 3.1 0.0 0.0 9.2 0.7 5.3 6.8 0.0 0.2 0.5 0.6 10.0 11.6 9.2 0.0 1.2 0.0 19.3 7.9 11.5 0.0 7.5 16.1 18.2 7.1 0.0 1.8 3.8 3.6 25.8 1.1 4.6 0.0 0.0 3.3 0.2 0.2 0.0 0.4 7.2 8.2 0.0 15.2 0.0 0.9 0.4 5.4 0.0 0.0 0.0 0.0 1.0 1.9 6.9 6.2 1.2 0.0 1.0 10.6 0.2 12.5 0.0 0.0 4.5 1.2 0.0 0.0 15.3 5.8 4.0 0.3 0.1 0.9 2.9 BFSP1 "CP115, CP94, filensin, LIFL-H" ENSG00000125864 "Beaded filament structural protein 1" Q12934 20 17493905-17569220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 5.7;NK-cells: 17.5;Spermatogonia: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.5" "Lineage enhanced" "Detected in single" "T-cells: 2.5" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 10.8;RPTEC TERT1: 19.5;SK-BR-3: 10.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "amygdala: 2.5;cerebral cortex: 3.2;hippocampal formation: 3.6" "HPA040748, HPA042038" Enhanced Supported "Plasma membrane,Cytosol" No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA040748: AB_10963786, HPA042038: AB_10964054" "unprognostic (2.24e-3)" "unprognostic (1.99e-1)" "unprognostic (1.63e-1)" "prognostic favorable (1.39e-4)" "unprognostic (1.07e-2)" "unprognostic (2.21e-1)" "unprognostic (1.22e-6)" "unprognostic (5.11e-2)" "unprognostic (5.53e-1)" "unprognostic (2.10e-4)" "unprognostic (1.75e-1)" "unprognostic (8.81e-2)" "unprognostic (3.35e-4)" "unprognostic (4.45e-2)" "unprognostic (2.73e-2)" "unprognostic (1.78e-2)" "unprognostic (7.50e-2)" 1.1 1.3 2.0 0.5 2.2 0.4 1.1 1.6 2.1 1.3 2.0 1.3 0.3 1.8 1.4 1.1 1.3 1.3 0.7 2.2 2.1 3.7 0.3 1.7 0.3 1.7 1.8 1.5 1.9 1.0 0.9 1.9 1.8 1.2 0.5 0.4 1.5 1.1 0.3 1.0 0.7 1.1 1.5 0.4 0.9 3.8 2.1 0.2 2.5 0.4 0.3 1.3 0.9 2.4 0.8 8.1 2.6 0.3 0.7 2.6 0.4 2.0 9.5 1.3 1.2 3.7 7.0 0.0 1.6 1.2 5.1 1.2 2.8 1.6 1.0 1.8 2.1 0.6 1.2 1.1 1.5 0.5 0.9 3.1 4.9 0.7 2.3 10.8 5.7 0.5 0.3 0.4 4.2 1.6 0.0 1.2 6.1 5.2 2.2 0.0 1.8 0.4 19.5 1.5 2.7 0.3 2.4 10.6 4.3 1.2 5.2 1.8 6.5 0.3 0.6 0.7 2.0 0.0 0.1 0.0 1.4 0.0 1.6 0.0 0.0 0.0 2.5 0.0 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.3 0.7 0.0 0.0 0.0 0.2 2.0 2.2 1.6 2.1 2.2 2.1 1.7 1.8 1.8 1.5 2.1 2.4 3.8 3.2 1.7 0.7 0.0 0.9 0.5 0.7 0.0 0.2 1.9 1.5 1.2 1.5 0.4 0.0 0.0 1.2 2.6 0.1 1.9 0.8 1.3 1.1 0.4 3.1 0.0 0.8 2.1 0.9 1.7 1.2 1.5 0.6 0.0 0.2 3.9 0.2 0.5 0.0 1.2 0.2 0.0 0.0 0.8 5.7 1.8 0.2 1.8 2.8 0.0 1.0 17.5 0.5 1.1 0.8 0.0 0.0 0.4 0.4 0.0 0.3 1.8 0.1 0.0 0.5 1.0 1.1 11.9 1.1 0.9 0.4 1.0 0.4 0.3 0.5 BLNK "BASH, bca, BLNK-s, Ly57, SLP-65, SLP65" ENSG00000095585 "B cell linker" Q8WV28 10 96189171-96271587 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 70.5" "Cell type enhanced" "Detected in many" "B-cells: 94.2;dendritic cells: 64.0;Microglial cells: 157.4;Plasma cells: 80.4;Proximal enterocytes: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "memory B-cell: 161.2;naive B-cell: 140.5;plasmacytoid DC: 231.5" "Group enriched" "Detected in many" 101 "B-cells: 161.2;dendritic cells: 231.5" "Group enriched" "Detected in some" 6 "Daudi: 68.7;REH: 168.4;RPMI-8226: 94.4;U-698: 251.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009333, CAB016291, HPA038309, HPA038310" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" Vesicles "CAB009333: AB_2290422, CAB016291: AB_626752, HPA038309: AB_2675945, HPA038310: AB_2675946" "unprognostic (4.86e-2)" "unprognostic (6.05e-3)" "unprognostic (1.00e-2)" "unprognostic (2.73e-2)" "unprognostic (2.29e-1)" "unprognostic (1.63e-3)" "unprognostic (1.08e-2)" "unprognostic (5.19e-2)" "unprognostic (2.97e-1)" "unprognostic (1.02e-1)" "unprognostic (8.94e-2)" "unprognostic (3.73e-1)" "unprognostic (1.84e-2)" "unprognostic (5.23e-2)" "unprognostic (9.76e-2)" "unprognostic (1.46e-3)" "prognostic favorable (2.67e-6)" 2.2 3.2 3.8 27.5 3.4 10.1 6.3 2.4 4.1 7.1 13.9 16.9 38.9 2.4 30.1 39.9 6.1 10.8 1.0 3.5 5.1 28.5 39.2 6.6 57.6 4.7 4.0 1.5 12.1 17.4 1.8 6.4 5.0 7.3 18.2 1.4 10.9 13.2 0.5 8.0 34.0 3.0 3.8 54.0 29.2 1.3 4.9 10.6 11.6 1.1 70.5 9.9 15.8 5.2 0.3 0.1 0.1 0.2 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.2 0.2 68.7 0.4 0.0 0.3 0.6 0.1 0.8 0.1 5.5 0.2 0.3 0.3 0.1 0.0 0.1 1.4 0.1 8.7 0.0 0.0 0.1 0.0 0.8 0.3 6.4 0.0 0.7 0.4 0.2 0.2 0.2 0.0 168.4 0.3 94.4 0.9 13.0 0.3 0.3 0.2 15.1 0.1 0.2 23.7 1.1 0.2 0.2 0.8 0.1 0.2 5.4 0.4 251.4 0.1 0.5 0.1 0.3 1.6 0.2 0.3 1.3 0.1 161.2 0.3 0.2 20.6 140.5 0.1 0.1 1.1 1.9 0.1 231.5 0.6 8.1 3.8 3.4 2.4 4.1 3.5 5.1 4.7 4.0 5.0 3.8 4.9 5.2 0.4 6.4 7.7 0.7 94.2 1.1 21.0 13.1 21.1 0.0 4.1 3.4 1.2 30.0 7.3 40.5 0.0 23.0 64.0 9.2 27.4 14.6 3.1 14.4 1.9 0.3 4.9 5.3 1.0 13.8 17.5 0.7 35.7 22.9 1.3 0.0 2.9 27.8 22.8 0.0 1.3 19.4 30.5 9.0 13.8 1.1 0.3 18.2 1.8 157.4 4.8 0.0 0.0 2.5 0.9 4.4 22.4 0.0 80.4 5.1 64.6 2.3 3.4 0.0 6.6 0.3 0.7 1.6 0.1 34.7 1.4 41.5 3.6 0.5 22.5 23.8 BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376327-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.2;Inhibitory neurons: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA017385: AB_1845397, HPA049014: AB_2680599" "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" 18.5 21.6 8.2 10.9 14.1 2.2 13.2 3.2 16.8 22.6 0.3 13.6 8.5 20.0 11.3 12.4 14.9 17.3 21.5 16.0 14.8 17.4 15.6 29.1 7.2 6.2 7.7 16.8 10.4 17.5 8.5 34.0 10.0 17.1 13.0 26.7 11.0 13.9 10.9 10.9 8.6 24.3 3.9 13.1 11.7 11.3 10.6 9.0 18.2 23.1 9.4 20.6 12.4 5.9 13.3 12.3 12.6 19.7 34.2 31.9 23.8 27.2 28.3 23.6 23.9 10.8 19.6 4.7 30.7 58.2 19.9 24.5 16.8 21.4 41.6 13.8 11.2 14.2 12.6 16.8 22.7 4.0 10.7 24.2 21.5 17.1 22.8 40.6 73.9 5.6 9.3 22.5 33.8 24.8 3.4 3.6 6.9 6.6 11.1 9.1 24.3 7.1 21.3 27.9 12.6 12.7 28.9 17.7 32.7 32.0 13.2 9.5 75.9 48.0 24.4 16.3 16.7 3.1 4.1 1.3 11.3 9.0 13.9 0.1 0.6 0.2 0.9 0.5 0.6 0.3 0.3 0.5 0.6 0.4 0.7 0.3 0.1 0.3 0.9 0.7 1.0 0.3 8.2 14.1 3.2 16.8 16.0 14.8 6.2 7.7 10.0 3.9 10.6 5.9 116.9 105.8 40.3 104.5 15.2 33.4 18.0 34.9 13.6 54.3 29.2 29.7 55.5 15.7 38.8 20.2 81.3 16.9 17.8 25.2 1.9 27.2 2.8 23.1 54.5 152.2 25.1 6.9 202.2 28.1 22.6 47.7 16.8 36.4 23.5 155.1 143.1 19.9 18.7 35.3 190.2 16.3 20.3 24.2 31.7 4.6 33.8 23.5 42.7 170.5 20.2 39.9 16.5 152.8 55.1 46.8 21.1 42.9 9.5 23.9 16.4 12.4 28.0 31.7 65.7 48.8 62.4 33.2 25.0 21.2 35.9 20.0 13.1 0.8 15.5 24.8 BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "epididymis: 102.6" "Group enriched" "Detected in some" 4 "Endothelial cells: 28.2;Hepatic stellate cells: 93.9" "Cancer enhanced" "Detected in many" "melanoma: 3.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 77 "granulocytes: 7.6" "Cell line enriched" "Detected in some" 119 "HUVEC TERT2: 353.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "CAB032495: AB_2290760, HPA001048: AB_1078289" "unprognostic (7.80e-2)" "unprognostic (4.92e-3)" "unprognostic (1.16e-2)" "unprognostic (4.07e-3)" "unprognostic (2.69e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-3)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (1.26e-2)" "unprognostic (1.84e-2)" "unprognostic (3.64e-2)" "unprognostic (1.26e-1)" "unprognostic (2.81e-2)" 7.7 0.3 0.3 1.7 0.5 7.1 4.9 0.3 0.6 1.7 1.1 3.8 4.4 2.3 102.6 2.3 2.6 2.6 8.8 0.3 0.3 0.6 0.7 3.0 1.5 0.3 0.4 0.9 0.9 0.3 0.2 4.7 0.3 0.9 2.4 0.0 1.1 0.9 1.3 1.6 4.8 2.6 0.3 2.2 1.4 0.2 0.4 0.7 2.0 2.2 0.4 2.6 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 353.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.3 0.6 0.3 0.3 0.3 0.4 0.3 0.3 0.4 0.4 14.1 0.0 1.1 1.3 0.0 0.4 0.7 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.2 0.0 28.2 4.2 3.2 1.3 0.2 0.0 1.1 4.6 0.2 0.0 0.1 93.9 0.7 0.1 0.0 1.2 0.1 2.0 0.0 1.1 0.0 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.8 0.0 0.0 0.3 0.8 0.2 0.1 0.2 0.0 0.1 0.2 0.1 0.4 0.4 BOC CDON2 ENSG00000144857 "BOC cell adhesion associated, oncogene regulated" Q9BWV1 3 113211003-113287459 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 71.8;Basal squamous epithelial cells: 112.1;Fibroblasts: 55.4;Leydig cells: 84.8;Peritubular cells: 47.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 79.2;ASC diff: 113.6;BJ hTERT+: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025806 Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" "Intracellular and membrane" NA No 7900000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies, Plasma membrane" Nucleoplasm "CAB025806: " "unprognostic (6.89e-3)" "unprognostic (1.34e-2)" "unprognostic (2.62e-3)" "unprognostic (1.03e-2)" "unprognostic (5.03e-3)" "prognostic favorable (4.89e-4)" "unprognostic (8.66e-5)" "unprognostic (1.10e-1)" "unprognostic (1.19e-2)" "unprognostic (4.78e-3)" "unprognostic (3.42e-2)" "unprognostic (1.10e-1)" "unprognostic (3.65e-3)" "unprognostic (4.94e-3)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.18e-5)" 41.6 5.8 15.8 10.4 15.5 0.2 29.8 13.1 12.1 26.0 33.2 49.1 4.9 46.6 10.1 24.9 63.2 19.3 14.3 17.1 15.2 9.7 1.0 6.6 3.6 53.2 30.1 35.2 16.1 2.7 20.8 2.2 23.2 33.8 4.6 3.2 23.8 21.3 6.3 34.9 18.3 32.6 32.3 4.6 19.0 5.0 26.3 5.7 24.6 9.0 3.1 32.5 25.8 23.4 0.0 7.6 27.6 79.2 113.6 6.0 0.9 12.8 41.9 3.2 2.7 0.0 0.0 0.1 7.8 21.8 1.7 0.0 5.6 2.7 1.1 0.0 3.4 0.0 2.3 0.0 0.6 0.3 0.2 19.7 1.8 1.7 0.2 25.7 0.0 0.0 0.1 0.0 0.6 2.1 0.2 1.4 7.0 0.0 6.9 0.2 12.3 0.0 0.7 0.1 8.2 11.7 0.1 0.5 0.3 8.1 3.4 0.4 0.0 4.5 7.3 0.1 4.2 0.0 0.0 0.0 9.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 15.5 13.1 12.1 17.1 15.2 53.2 30.1 23.2 32.3 26.3 23.4 9.6 0.0 0.5 71.8 0.0 21.2 3.1 3.6 112.1 0.6 3.7 17.3 1.1 1.5 0.7 5.5 0.0 4.8 0.2 0.0 0.0 0.1 1.4 12.6 10.5 5.6 1.8 0.0 8.8 0.0 4.3 55.4 0.5 11.7 0.0 5.7 3.3 0.1 0.8 0.0 2.5 0.0 0.0 0.3 5.5 3.3 84.8 1.0 10.6 6.5 0.0 12.2 0.0 24.1 0.7 0.3 0.0 47.8 0.6 3.3 0.0 0.0 0.3 0.5 0.0 18.0 13.5 1.5 3.2 11.5 11.1 1.9 0.8 1.1 0.0 0.9 BTK "AGMX1, ATK, IMD1, PSCTK1, XLA" ENSG00000010671 "Bruton tyrosine kinase" Q06187 X 101349447-101390796 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.6;lymphoid tissue: 78.0" "Cell type enhanced" "Detected in some" "B-cells: 84.7;granulocytes: 211.4;Hofbauer cells: 56.6;Kupffer cells: 63.5;Macrophages: 61.1;monocytes: 71.1;Plasma cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 557.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 557.5" "Cell line enhanced" "Detected in some" "Daudi: 206.7;HEL: 287.4;HMC-1: 990.3;U-937: 149.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001198, HPA002028, CAB016689" Enhanced Supported "Plasma membrane,Cytosol" NA NA 2300000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" "CAB016689: AB_1611894, HPA001198: AB_1078305, HPA002028: AB_1078306" "unprognostic (3.19e-2)" "unprognostic (2.51e-3)" "unprognostic (1.06e-2)" "unprognostic (3.66e-2)" "unprognostic (5.69e-2)" "unprognostic (3.76e-3)" "unprognostic (6.55e-2)" "unprognostic (3.58e-3)" "unprognostic (6.02e-2)" "unprognostic (3.12e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (2.08e-3)" "unprognostic (7.80e-2)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (8.14e-2)" 6.3 2.9 2.3 30.7 2.6 32.6 4.4 2.8 3.4 3.9 3.1 6.6 4.8 2.5 1.5 3.6 1.9 7.6 1.6 2.3 3.1 1.3 5.4 19.6 55.5 4.7 3.6 0.8 1.2 0.9 0.9 7.0 4.7 1.9 9.1 0.3 2.8 2.3 0.6 2.9 14.7 7.1 3.8 38.4 7.0 1.4 3.9 9.3 1.3 2.0 78.0 9.3 1.5 6.5 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 206.7 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.3 287.4 0.0 0.0 0.0 116.7 990.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 61.9 2.3 0.0 0.0 0.6 81.5 1.6 0.0 0.0 87.2 0.1 13.2 0.0 0.0 0.2 0.0 0.3 0.1 0.5 1.0 0.0 68.5 0.4 0.0 0.3 0.2 0.1 2.6 1.4 98.3 0.5 149.8 0.3 557.5 62.2 110.5 0.2 99.9 0.2 72.4 0.2 0.1 72.7 73.0 0.4 0.1 24.7 0.2 123.9 33.1 0.1 38.4 2.3 2.6 2.8 3.4 2.3 3.1 4.7 3.6 4.7 3.8 3.9 6.5 1.5 3.2 8.9 0.3 84.7 1.0 0.2 0.0 0.6 0.0 0.9 1.4 0.6 0.0 0.6 0.0 0.0 1.4 30.1 0.1 0.0 0.0 0.2 1.3 0.3 0.8 0.0 27.1 0.5 0.0 0.5 0.9 1.1 2.3 211.4 0.0 0.7 0.3 56.6 0.0 0.3 0.3 0.0 63.5 31.0 0.1 0.3 61.1 3.6 10.3 71.1 0.0 2.1 0.0 0.1 0.1 0.5 0.0 43.8 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.5 0.7 1.7 0.5 0.3 1.9 5.7 0.2 0.1 0.1 BVES "HBVES, POP1, POPDC1" ENSG00000112276 "Blood vessel epicardial substance" Q8NE79 6 105096822-105137157 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Developmental protein" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 27.8;skeletal muscle: 43.9;tongue: 29.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 34.2;Early spermatids: 36.1;Late spermatids: 55.3;Oligodendrocytes: 17.8;Spermatocytes: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 29.7;WM-115: 30.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA014788, HPA018176" Enhanced Supported "Plasma membrane,Cell Junctions" Yes NA "Cluster 17: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "HPA014788: AB_1845504, HPA018176: AB_1845503" "unprognostic (2.91e-1)" "unprognostic (2.45e-1)" "unprognostic (2.79e-2)" "unprognostic (1.73e-2)" "unprognostic (5.46e-2)" "unprognostic (3.66e-2)" "unprognostic (5.21e-2)" "unprognostic (2.22e-2)" "unprognostic (8.37e-2)" "unprognostic (4.49e-2)" "unprognostic (2.29e-2)" "unprognostic (8.92e-2)" "unprognostic (5.84e-3)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "unprognostic (2.02e-2)" "unprognostic (3.24e-4)" 2.9 0.7 2.6 2.3 7.1 0.2 1.5 5.8 3.6 2.5 4.6 14.9 1.4 5.8 1.7 5.3 2.8 1.8 27.8 2.7 4.3 1.6 0.3 1.9 0.6 7.3 5.6 1.0 0.6 0.7 2.4 3.5 7.4 5.2 3.3 0.2 1.4 10.0 43.9 0.7 3.0 17.7 5.2 0.3 6.9 11.5 5.2 0.2 1.3 29.3 0.4 9.3 2.2 10.8 1.3 2.0 7.6 1.3 10.9 14.9 3.3 5.8 4.1 8.8 11.6 0.5 0.0 0.0 0.0 10.9 14.7 0.1 3.3 2.0 8.1 0.0 2.8 0.0 1.0 0.3 2.4 0.0 0.6 8.7 6.9 13.6 1.1 6.6 4.0 3.3 0.1 19.3 19.7 0.1 0.2 1.0 1.6 0.0 0.0 5.7 29.7 0.0 0.0 0.0 9.9 17.1 3.7 0.1 7.7 5.5 0.0 20.0 8.9 14.0 0.0 0.0 15.3 1.8 0.8 0.0 8.3 0.0 30.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 2.6 7.1 5.8 3.6 2.7 4.3 7.3 5.6 7.4 5.2 5.2 10.8 2.1 0.0 0.0 1.6 0.0 0.3 0.4 0.1 0.6 0.0 0.4 1.0 34.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 36.1 1.9 4.4 3.1 0.0 0.0 3.3 0.0 0.2 2.6 0.0 6.0 0.0 0.9 2.2 0.1 2.3 0.0 0.6 0.0 0.0 0.0 1.9 55.3 1.2 0.5 0.0 3.7 1.0 0.0 0.0 5.0 17.8 0.1 0.0 3.4 0.0 0.5 0.1 0.1 0.1 0.0 13.1 11.8 4.4 24.4 5.4 0.1 0.9 0.1 0.2 1.3 0.0 0.3 C2CD2L "KIAA0285, TMEM24" ENSG00000172375 "C2CD2 like" O14523 11 119102198-119118544 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Distal enterocytes: 40.6;Proximal enterocytes: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HMC-1: 50.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011044, HPA075369" Approved Supported "Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA011044: AB_2668414, HPA075369: " "unprognostic (3.43e-2)" "unprognostic (2.81e-2)" "unprognostic (1.03e-3)" "prognostic favorable (4.92e-4)" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (2.25e-3)" "unprognostic (3.37e-3)" "unprognostic (5.28e-2)" "unprognostic (2.09e-1)" "unprognostic (3.99e-3)" "unprognostic (8.19e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (8.02e-2)" "unprognostic (8.32e-3)" "unprognostic (4.10e-2)" "unprognostic (2.60e-1)" 6.6 8.2 26.9 6.5 27.6 13.6 5.8 15.5 28.9 6.4 15.3 11.1 16.1 6.2 4.8 10.8 8.8 5.3 10.2 26.8 19.6 11.6 13.1 10.3 8.1 18.0 18.4 6.0 11.0 5.7 23.9 3.9 18.4 7.1 7.3 14.1 9.6 5.3 15.3 15.3 17.1 5.1 15.2 14.9 8.1 4.3 21.4 8.5 6.7 7.3 5.7 7.0 6.6 23.7 6.1 4.5 6.0 12.5 7.7 3.2 3.9 9.0 7.8 8.7 7.2 7.3 6.3 9.1 23.1 6.3 9.1 13.4 7.6 3.9 3.4 14.3 6.2 35.7 5.9 5.3 10.2 10.5 50.5 3.7 7.9 16.4 6.1 9.8 5.4 13.5 15.1 16.1 8.3 16.2 11.9 24.9 2.2 15.0 11.8 7.4 5.3 10.5 8.7 3.8 18.7 10.5 3.8 20.1 5.9 2.3 35.3 13.9 6.7 8.1 2.8 9.9 16.1 6.8 4.5 3.5 4.9 17.6 9.1 0.5 1.3 2.7 0.2 1.4 0.4 0.1 0.6 0.6 0.5 0.0 0.6 0.3 0.4 0.8 2.0 0.3 0.6 0.5 26.9 27.6 15.5 28.9 26.8 19.6 18.0 18.4 18.4 15.2 21.4 23.7 5.1 6.4 4.2 9.4 3.7 10.7 1.6 2.3 10.2 15.6 6.8 5.0 2.4 2.8 4.3 1.8 37.5 0.9 7.4 40.6 3.9 3.4 5.4 12.1 2.6 5.7 1.2 7.0 15.1 2.8 1.7 2.5 3.6 4.6 2.5 2.2 11.4 5.4 9.4 21.9 15.0 8.0 0.0 13.9 16.1 1.3 2.1 11.4 7.2 5.6 15.3 5.9 7.2 4.5 8.4 5.1 10.4 1.5 7.2 3.2 33.0 4.0 21.9 29.9 6.6 2.1 3.6 3.7 2.0 10.3 10.9 1.1 8.6 3.6 5.5 1.9 CA9 "CAIX, MN" ENSG00000107159 "Carbonic anhydrase 9" Q16790 9 35673918-35681159 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "stomach 1: 289.3" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 275.3;Cholangiocytes: 62.9;Early spermatids: 205.8;Gastric mucus-secreting cells: 259.5" "Cancer enhanced" "Detected in many" "renal cancer: 85.9" "Region enriched" "Detected in single" 9 "cerebellum: 5.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "A-431: 189.3;HDLM-2: 98.1;hTERT-RPE1: 113.1;U-87 MG: 374.4" "Region enhanced" "Detected in many" "cerebellum: 12.3" "Low region specificity" "Detected in all" "CAB005100, CAB017107, HPA055207" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB005100: AB_2066539, CAB017107: , HPA055207: AB_2682738" "unprognostic (8.01e-3)" "unprognostic (1.34e-2)" "unprognostic (2.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.71e-5)" "unprognostic (1.47e-2)" "unprognostic (3.90e-2)" "unprognostic (1.29e-1)" "unprognostic (6.24e-3)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.22e-7)" "unprognostic (7.29e-2)" "prognostic favorable (9.50e-4)" "unprognostic (2.97e-3)" "unprognostic (8.67e-2)" 3.8 0.4 0.0 0.2 0.0 0.0 0.1 5.6 0.6 0.5 0.0 0.6 14.5 0.2 0.1 0.8 0.4 24.4 2.0 0.2 0.1 0.2 1.3 0.2 0.0 0.0 0.1 0.7 6.6 0.0 0.5 0.0 0.2 0.5 0.0 1.0 0.1 0.1 0.1 8.2 13.6 0.1 0.0 0.0 289.3 5.5 0.5 0.0 0.0 0.0 0.0 0.7 0.7 0.0 189.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 3.6 0.3 2.5 0.0 0.1 0.0 0.1 0.0 0.5 5.7 0.0 0.9 1.5 98.1 0.0 0.0 0.7 0.4 0.0 0.0 0.2 0.4 0.0 0.0 0.3 113.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.3 0.2 0.5 0.0 0.0 10.6 0.0 0.6 1.6 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 18.9 0.4 0.0 4.7 0.0 0.4 0.1 374.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.6 0.6 0.2 0.1 0.0 0.1 0.2 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 4.5 0.7 275.3 0.0 0.4 0.1 0.0 0.4 62.9 28.1 0.0 0.0 0.0 0.0 0.1 0.0 49.1 205.8 0.0 0.1 0.2 0.0 0.0 0.1 50.9 0.6 1.2 259.5 0.2 0.0 0.4 0.7 0.0 0.1 0.0 0.6 4.0 18.3 0.0 0.0 19.6 1.5 0.1 0.0 0.0 0.6 1.3 0.0 0.0 0.0 26.6 0.0 0.7 0.3 0.8 0.7 0.1 5.5 0.0 0.0 0.0 1.5 0.9 4.0 0.0 3.1 0.3 0.1 0.7 5.3 0.4 CALCRL "CGRPR, CRLR" ENSG00000064989 "Calcitonin receptor like receptor" Q16602 2 187341964-187448460 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 70.7;lung: 76.8" "Cell type enhanced" "Detected in many" "Adipocytes: 138.3;Endometrial stromal cells: 92.7;Endothelial cells: 248.7;Hepatic stellate cells: 259.2;Oligodendrocyte precursor cells: 293.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.6;myeloid DC: 9.2;plasmacytoid DC: 2.6" "Group enriched" "Detected in many" 6 "dendritic cells: 9.2;monocytes: 2.6" "Cell line enriched" "Detected in some" 4 "HUVEC TERT2: 173.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008070, HPA046515" Uncertain Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA008070: AB_1845912, HPA046515: AB_2679681" "unprognostic (7.06e-2)" "unprognostic (5.71e-2)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (3.44e-3)" "unprognostic (7.60e-3)" "unprognostic (9.25e-3)" "unprognostic (4.14e-2)" "unprognostic (7.71e-3)" "unprognostic (3.32e-1)" "unprognostic (3.77e-1)" "unprognostic (3.44e-1)" "unprognostic (1.51e-3)" "unprognostic (1.90e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" 70.7 6.3 3.4 12.3 4.0 0.4 15.8 6.1 4.4 27.8 3.4 6.9 6.0 21.5 4.6 8.6 11.4 24.4 20.4 3.9 3.8 14.0 12.6 76.8 7.9 11.1 6.2 15.7 4.3 13.0 3.6 11.7 10.8 7.3 9.5 0.9 7.1 7.7 6.2 3.9 6.3 27.1 15.5 8.6 7.1 2.7 3.9 4.6 28.3 20.2 9.1 14.1 4.7 15.2 0.2 0.0 8.8 0.0 6.2 1.6 0.0 0.8 1.3 0.1 1.0 0.0 1.0 0.0 2.3 0.7 0.2 0.0 0.0 0.6 0.2 1.5 0.5 1.5 0.0 0.2 4.9 0.2 0.0 4.6 0.2 0.3 2.1 0.5 173.6 0.1 0.0 2.5 1.2 0.0 0.8 0.1 0.5 0.0 0.0 0.0 3.1 0.5 40.5 0.0 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.2 25.3 0.7 0.1 0.1 0.4 6.2 0.1 0.7 0.4 0.0 0.0 0.0 2.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 9.2 0.0 0.8 0.1 0.1 1.0 1.0 2.6 0.0 0.9 3.4 4.0 6.1 4.4 3.9 3.8 11.1 6.2 10.8 15.5 3.9 15.2 138.3 0.0 11.9 19.6 1.2 9.3 2.3 1.7 21.6 0.2 0.8 1.8 12.3 2.8 3.6 0.0 0.0 0.4 2.4 0.0 3.9 0.3 0.8 3.1 92.7 248.7 0.0 4.8 15.4 0.4 0.2 56.5 1.1 1.7 5.1 12.3 259.2 1.8 0.9 0.0 2.1 0.0 2.0 10.3 29.7 1.0 7.8 15.4 10.6 47.8 16.1 0.0 1.0 293.0 1.0 0.1 0.0 2.6 4.9 1.9 0.0 13.2 2.8 0.1 6.6 4.1 21.5 1.3 0.7 18.2 6.8 0.3 3.0 6.0 0.0 1.8 CAMK2B "CAM2, CAMK2, CAMKB, CaMKIIβ" ENSG00000058404 "Calcium/calmodulin dependent protein kinase II beta" Q13554 7 44217150-44334577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Actin-binding, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 248.8;skeletal muscle: 132.5" "Cell type enriched" "Detected in many" 7 "Bipolar cells: 857.4" "Cancer enhanced" "Detected in many" "glioma: 6.0;thyroid cancer: 6.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006849, HPA026307, HPA051783, HPA051785, HPA053973" Enhanced Supported Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA 600000 "Cluster 11: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "Cell Junctions, Cytosol" "CAB006849: , HPA026307: AB_1845941, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (1.88e-3)" "unprognostic (4.49e-2)" "unprognostic (3.55e-3)" "unprognostic (1.36e-2)" "unprognostic (5.25e-2)" "unprognostic (2.90e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-1)" "unprognostic (1.17e-2)" "unprognostic (1.60e-2)" "unprognostic (5.23e-7)" "unprognostic (7.04e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (3.95e-2)" 0.5 11.3 77.9 0.6 109.0 0.1 1.4 113.0 248.8 0.1 0.0 1.0 1.0 0.2 28.3 1.4 1.1 0.2 65.4 197.6 12.6 1.6 7.7 0.3 1.3 4.4 11.9 0.3 3.8 6.1 51.3 0.1 4.6 3.2 0.4 21.4 1.4 1.6 132.5 1.2 0.9 0.1 3.2 0.3 2.3 2.1 25.9 0.8 20.3 59.2 1.6 0.0 0.3 80.4 0.0 0.8 0.4 0.6 0.0 0.4 0.4 0.3 0.1 0.3 0.0 0.3 0.1 0.2 1.6 0.4 0.1 0.3 0.4 1.4 0.1 2.0 4.5 0.1 0.2 0.2 0.1 0.0 0.9 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.8 0.1 10.1 0.0 0.4 0.2 0.1 4.4 0.2 1.7 0.3 0.0 0.0 75.5 4.0 0.4 0.0 0.0 0.1 3.5 0.3 0.4 0.5 0.7 0.4 0.1 0.9 0.8 0.2 0.2 0.0 0.5 1.0 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 0.4 0.7 0.3 0.2 0.2 0.2 77.9 109.0 113.0 248.8 197.6 12.6 4.4 11.9 4.6 3.2 25.9 80.4 0.1 0.0 0.0 67.3 0.2 1.1 21.5 0.0 10.8 857.4 3.1 17.5 88.9 2.8 0.0 0.0 45.9 0.1 0.0 0.5 9.8 0.0 0.9 2.3 0.4 1.6 40.7 0.0 111.4 0.0 0.2 2.9 4.1 5.6 4.5 15.4 0.0 4.3 0.2 60.6 90.9 1.5 2.0 0.6 0.4 2.9 1.8 0.5 1.8 5.6 0.0 23.2 0.0 19.6 5.4 0.1 1.2 0.0 0.1 3.3 0.1 1.9 0.0 53.1 0.0 6.9 1.7 0.2 7.8 0.9 0.4 0.3 0.2 0.2 0.3 6.6 CASKIN2 "ANKS5B, FLJ21609, KIAA1139" ENSG00000177303 "CASK interacting protein 2" Q8WXE0 17 75500261-75515537 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.5;Endothelial cells: 42.2;Hepatic stellate cells: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071906, HPA075184" Enhanced Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA071906: AB_2732191, HPA075184: AB_2732281" "unprognostic (1.60e-1)" "unprognostic (4.54e-2)" "unprognostic (9.12e-3)" "unprognostic (5.27e-3)" "unprognostic (9.32e-2)" "unprognostic (5.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.10e-2)" "unprognostic (7.67e-2)" "unprognostic (1.33e-1)" "prognostic favorable (2.47e-5)" "unprognostic (1.82e-2)" "prognostic favorable (4.83e-8)" "unprognostic (1.43e-1)" "unprognostic (1.52e-1)" "unprognostic (1.39e-1)" "unprognostic (4.95e-2)" 33.8 22.7 19.4 4.9 22.6 0.4 30.0 19.7 18.6 15.1 4.6 16.5 9.0 21.0 2.7 10.8 21.7 11.2 28.2 16.7 17.2 26.9 11.3 42.3 2.9 22.6 21.7 12.0 10.8 9.4 13.6 11.8 18.7 14.9 2.9 4.8 11.5 8.7 15.3 12.7 11.4 10.4 18.1 30.8 15.0 5.6 20.0 2.9 22.6 9.9 1.5 16.0 14.3 23.1 13.3 17.2 10.2 14.4 6.6 4.1 11.2 6.6 8.7 15.8 10.2 19.0 5.6 0.5 7.4 7.7 10.5 12.0 8.2 7.7 3.9 4.7 10.8 9.4 17.2 7.5 7.7 0.5 12.6 3.5 10.4 8.2 5.9 5.3 16.2 13.3 6.9 1.6 5.0 31.1 24.3 0.7 7.5 10.3 17.5 12.8 21.8 2.1 10.2 13.4 10.4 10.2 13.9 18.7 11.0 8.7 13.7 4.0 13.9 16.1 14.6 7.9 8.7 1.2 5.9 1.5 5.6 0.3 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 22.6 19.7 18.6 16.7 17.2 22.6 21.7 18.7 18.1 20.0 23.1 75.5 3.2 2.2 11.1 1.3 8.0 2.5 3.5 6.8 6.5 5.8 5.0 11.4 2.8 1.8 9.2 10.4 2.2 0.6 11.7 3.9 5.1 0.5 2.8 4.4 42.2 7.7 8.0 1.3 5.3 1.9 6.0 8.2 5.7 0.0 14.9 56.7 6.8 2.7 3.3 1.7 4.3 8.2 4.1 3.1 2.3 8.1 1.2 1.8 7.5 2.0 28.2 0.0 15.1 8.3 6.0 6.0 11.3 1.6 2.5 8.4 3.1 1.4 6.8 0.0 5.5 6.4 2.7 4.4 4.5 7.0 2.2 0.5 5.7 4.6 2.2 CAVIN1 "cavin-1, CGL4, PTRF" ENSG00000177469 "Caveolae associated protein 1" Q6NZI2 17 42402449-42423256 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Transcription termination" "RNA-binding, rRNA-binding" "Congenital generalized lipodystrophy, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 575.1;Alveolar cells type 1: 429.5;Breast myoepithelial cells: 154.9;Cytotrophoblasts: 159.8;Endothelial cells: 217.4;Smooth muscle cells: 211.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 1105.9;fHDF/TERT166: 796.6;TIME: 920.9;U-138 MG: 912.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049838, HPA074213" Supported Supported "Vesicles,Plasma membrane" NA NA 440000 "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Vesicles "HPA049838: AB_2680907, HPA074213: AB_2686674" "unprognostic (1.59e-1)" "unprognostic (4.46e-2)" "prognostic unfavorable (6.36e-4)" "unprognostic (1.56e-1)" "unprognostic (1.76e-3)" "unprognostic (6.33e-3)" "unprognostic (1.72e-1)" "unprognostic (1.04e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (7.18e-3)" "unprognostic (2.36e-1)" "unprognostic (3.44e-3)" "unprognostic (4.24e-3)" "unprognostic (3.21e-2)" "unprognostic (2.07e-3)" "prognostic unfavorable (5.87e-4)" 397.8 65.3 42.6 69.1 47.2 3.7 295.3 55.8 40.9 239.9 50.6 314.0 30.8 344.3 56.8 101.0 207.5 78.1 220.9 35.4 49.7 66.4 21.0 202.8 30.0 68.8 55.0 162.5 28.4 26.5 34.8 151.3 60.1 181.5 50.7 3.6 84.2 215.4 144.8 161.9 104.1 242.3 53.5 109.0 132.8 22.6 47.2 16.6 112.4 92.7 24.0 255.4 192.3 58.0 315.9 264.8 5.5 69.8 342.3 409.6 6.9 1105.9 477.8 432.2 340.5 134.6 20.1 0.5 216.3 796.6 177.4 509.7 46.8 331.6 351.0 1.1 9.5 137.5 154.8 66.1 215.8 0.3 1.2 283.0 120.5 340.8 115.8 230.2 592.3 0.4 95.5 1.3 187.9 5.0 7.4 1.6 25.8 48.1 1.8 0.6 173.3 0.6 186.1 1.6 0.4 2.0 371.9 6.4 91.7 145.2 29.8 2.0 920.9 912.0 429.5 330.9 407.9 0.8 0.9 1.6 270.7 0.5 104.8 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 42.6 47.2 55.8 40.9 35.4 49.7 68.8 55.0 60.1 53.5 47.2 58.0 575.1 429.5 117.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 55.4 154.9 0.0 0.0 50.8 23.9 0.0 159.8 3.4 0.0 3.9 45.6 0.0 11.7 130.4 217.4 0.0 0.0 0.0 4.4 11.3 114.2 0.0 16.9 63.1 116.3 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.5 0.0 0.0 0.5 0.0 0.0 1.1 3.6 0.0 0.0 0.0 211.7 0.0 0.0 0.0 0.0 77.2 4.5 6.6 0.0 0.0 CAVIN4 "cavin-4, MURC" ENSG00000170681 "Caveolae associated protein 4" Q5BKX8 9 100578079-100588389 "Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 276.1;tongue: 92.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.5;Endometrial ciliated cells: 1.2;Endometrial stromal cells: 1.8;Glandular and luminal cells: 1.9;Granulosa cells: 1.8;Pancreatic endocrine cells: 1.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 8.9;SCLC-21H: 13.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020973, HPA020987, HPA021021" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA020973: AB_1853079, HPA020987: AB_1853080, HPA021021: AB_1853082" "unprognostic (9.54e-5)" "unprognostic (1.68e-2)" "unprognostic (2.50e-2)" "unprognostic (3.76e-2)" "unprognostic (4.92e-2)" "unprognostic (4.56e-3)" "unprognostic (1.14e-4)" "unprognostic (3.36e-2)" "unprognostic (2.23e-1)" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (4.02e-1)" "unprognostic (1.74e-8)" "unprognostic (1.14e-1)" "unprognostic (3.39e-1)" "unprognostic (3.68e-3)" "unprognostic (1.55e-3)" 0.2 0.1 1.6 0.2 2.9 0.1 0.1 2.0 5.6 0.4 0.4 0.4 0.0 0.5 0.1 4.3 0.1 0.3 45.9 1.7 2.5 0.2 0.2 0.4 0.1 2.7 2.7 0.2 0.1 0.0 0.2 0.3 2.7 4.5 0.1 0.3 2.4 0.1 276.1 0.2 0.1 0.3 1.8 0.1 0.3 3.7 2.7 0.4 0.5 92.4 0.1 0.3 0.2 3.5 0.5 0.3 6.1 2.2 1.4 2.0 4.3 1.1 0.9 0.8 1.0 0.0 0.4 0.2 0.3 0.6 2.1 0.3 3.1 0.1 1.7 1.4 2.0 0.1 1.0 0.0 0.4 0.2 0.4 5.0 0.3 0.8 0.5 1.5 1.1 1.5 0.2 0.2 3.9 0.1 1.8 0.3 8.9 1.0 0.7 2.6 5.8 0.0 0.8 0.3 13.2 3.4 0.2 0.2 1.1 4.1 0.1 0.2 1.1 1.5 1.2 1.0 1.0 0.3 1.1 0.6 1.7 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.9 2.0 5.6 1.7 2.5 2.7 2.7 2.7 1.8 2.7 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.7 0.0 1.2 1.8 0.3 0.0 0.0 0.0 0.5 0.4 0.5 0.0 1.9 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 33.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.1;Rod photoreceptor cells: 38.2;Theca cells: 78.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "basophil: 9.2" "Lineage enriched" "Detected in single" 19 "granulocytes: 9.2" "Cell line enhanced" "Detected in many" "BJ: 101.2;BJ hTERT+: 103.2;BJ hTERT+ SV40 Large T+ RasG12V: 96.4;HBF TERT88: 113.3;hTERT-HME1: 153.2;LHCN-M2: 176.9;TIME: 93.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in many" "HPA041361, HPA041374" Uncertain Supported "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA041361: AB_10796667, HPA041374: AB_10794515" "unprognostic (3.09e-1)" "unprognostic (5.01e-2)" "unprognostic (9.54e-5)" "unprognostic (1.66e-2)" "unprognostic (2.40e-2)" "unprognostic (5.68e-5)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" "unprognostic (2.17e-2)" "unprognostic (3.62e-3)" "unprognostic (4.04e-3)" "unprognostic (1.64e-1)" "unprognostic (7.45e-2)" "unprognostic (2.02e-2)" 4.1 10.2 2.7 1.2 3.4 0.5 1.8 2.2 3.0 10.5 0.7 16.7 1.1 6.9 0.5 2.8 8.3 1.3 2.1 6.5 1.1 3.3 5.7 9.9 1.3 0.2 1.9 33.5 1.1 2.9 0.4 0.5 0.3 2.4 2.8 1.1 0.6 4.0 15.3 3.0 2.5 3.2 0.2 0.5 1.6 0.6 3.7 1.2 0.9 0.9 0.7 0.8 1.3 1.5 20.6 1.9 0.0 0.2 15.1 47.2 30.7 101.2 103.2 73.5 96.4 0.3 0.3 0.4 0.2 40.6 16.7 2.3 0.2 65.5 113.3 0.4 0.3 0.2 0.4 0.3 35.1 0.3 0.2 32.0 2.9 57.0 153.2 31.2 3.6 0.3 0.2 0.5 176.9 0.6 0.1 0.2 0.3 0.0 0.6 0.1 0.2 0.2 3.9 2.0 0.4 0.7 0.3 0.2 0.9 7.2 0.3 0.5 93.3 0.2 10.0 15.3 0.3 0.3 0.3 0.2 5.0 0.3 2.4 9.2 0.2 0.5 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.5 0.4 0.1 0.2 0.1 0.1 2.7 3.4 2.2 3.0 6.5 1.1 0.2 1.9 0.3 0.2 3.7 1.5 1.5 3.2 1.3 3.9 0.2 4.6 2.0 1.0 2.2 6.4 0.8 0.4 1.6 2.8 1.9 0.0 8.4 1.0 0.2 0.2 0.0 0.2 0.8 8.8 5.1 2.2 0.0 0.0 56.1 0.2 1.3 14.5 0.0 0.6 1.3 6.8 9.7 0.2 0.4 15.2 15.1 0.0 0.0 1.0 8.9 1.1 9.6 0.5 7.2 1.0 0.2 2.4 0.0 0.5 0.7 0.3 0.0 0.4 0.1 1.5 0.1 0.1 0.9 38.2 0.0 1.6 5.9 0.4 0.9 0.2 4.3 0.8 1.2 78.0 0.1 0.9 CCDC115 "ccp1, FLJ30131, MGC12981" ENSG00000136710 "Coiled-coil domain containing 115" Q96NT0 2 130337933-130342699 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034598 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" Vesicles "HPA034598: AB_10601697" "prognostic favorable (7.59e-4)" "unprognostic (1.28e-2)" "unprognostic (1.10e-3)" "unprognostic (6.80e-3)" "unprognostic (3.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.20e-2)" "unprognostic (8.13e-3)" "unprognostic (2.63e-1)" "unprognostic (4.29e-1)" "unprognostic (2.87e-1)" "unprognostic (1.91e-2)" "unprognostic (1.19e-2)" "unprognostic (1.07e-1)" "unprognostic (7.83e-2)" "unprognostic (2.16e-1)" "unprognostic (3.16e-2)" 27.8 25.1 25.3 18.0 25.8 24.8 25.4 26.4 28.0 33.7 21.7 25.3 21.2 29.5 32.3 31.1 29.9 19.9 18.4 25.2 26.6 29.8 17.8 26.6 29.8 26.8 25.3 41.6 20.2 40.2 22.9 13.8 26.3 24.0 19.3 15.8 29.1 27.7 12.9 39.3 24.2 17.7 26.1 26.1 24.1 10.4 25.4 23.3 30.3 12.3 26.0 26.8 28.1 27.5 22.5 10.5 13.3 8.1 27.2 30.7 16.3 10.5 28.2 22.4 26.1 24.4 48.5 25.7 36.6 18.3 11.4 20.7 10.8 19.2 16.1 33.4 20.2 20.2 5.4 27.3 22.7 20.8 40.2 26.2 44.2 14.6 8.1 21.8 23.7 24.3 19.8 22.6 27.7 20.7 38.5 37.5 17.2 11.2 26.4 29.4 14.2 24.1 18.8 18.6 12.4 22.8 12.3 22.4 24.2 8.7 24.5 25.3 18.6 10.1 10.4 18.5 8.3 12.4 13.0 19.7 22.9 22.1 13.5 129.9 94.6 154.8 80.8 136.0 71.8 96.3 85.1 85.8 95.2 98.9 81.1 74.8 33.3 80.6 174.9 73.8 103.6 132.8 25.3 25.8 26.4 28.0 25.2 26.6 26.8 25.3 26.3 26.1 25.4 27.5 37.5 19.2 28.3 3.6 43.6 51.9 42.3 104.2 40.5 25.9 43.3 41.9 13.9 35.8 50.8 77.3 10.4 76.7 35.1 29.9 105.7 47.4 1.4 14.5 16.9 30.8 27.6 13.5 8.7 42.7 36.6 30.6 21.4 20.3 53.3 22.7 33.2 21.4 63.5 23.5 12.3 35.6 99.7 45.5 60.7 4.5 42.6 49.4 53.4 5.6 97.3 48.4 49.4 10.1 12.2 27.5 49.1 52.3 16.9 14.9 51.9 65.9 24.3 27.6 46.0 29.2 31.7 9.0 24.0 42.4 70.0 26.4 51.3 39.1 41.6 30.0 CCKAR ENSG00000163394 "Cholecystokinin A receptor" P32238 4 26481396-26490484 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.9;gallbladder: 29.2;stomach 1: 16.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "stomach cancer: 0.5" "Group enriched" "Detected in some" 5 "hypothalamus: 5.1;midbrain: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 7.2" "Region enhanced" "Detected in all" "midbrain: 12.6" HPA073900 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA073900: " "unprognostic (7.48e-2)" "unprognostic (3.70e-2)" "unprognostic (7.13e-2)" "unprognostic (3.08e-2)" "unprognostic (3.36e-1)" "unprognostic (3.79e-1)" 0.0 0.0 0.5 0.0 0.4 0.0 0.1 0.0 0.4 0.0 0.0 0.3 1.6 0.0 0.0 0.0 0.0 29.2 0.0 0.6 5.1 0.1 0.0 0.0 0.0 0.8 6.9 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 16.5 0.1 1.1 0.3 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.4 0.6 5.1 0.8 6.9 0.6 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCR2 "CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R" ENSG00000121807 "C-C motif chemokine receptor 2" P41597 3 46353744-46360940 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in some" "dendritic cells: 40.4;Kupffer cells: 43.1;Macrophages: 25.2;monocytes: 34.9;Plasma cells: 26.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 560.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Karpas-707: 185.5;THP-1: 89.8;U-266/70: 416.5;U-266/84: 177.7" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 2.4" "CAB003793, HPA063255" Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Nucleoli fibrillar center" "CAB003793: AB_344889, HPA063255: " "unprognostic (1.09e-2)" "unprognostic (6.28e-4)" "unprognostic (3.49e-2)" "unprognostic (6.35e-4)" "unprognostic (1.89e-2)" "unprognostic (4.16e-4)" "unprognostic (8.06e-2)" "prognostic favorable (5.87e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (3.12e-1)" "unprognostic (1.56e-1)" "unprognostic (5.52e-3)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (4.88e-2)" "unprognostic (4.19e-1)" 2.6 1.9 0.1 25.9 0.1 1.9 3.1 0.1 0.2 1.6 0.3 4.6 7.5 1.2 0.9 1.2 1.2 3.4 1.1 0.1 0.1 1.2 2.1 5.8 11.6 0.4 0.2 1.1 0.8 0.3 0.2 0.8 0.2 1.2 5.1 0.0 3.1 1.7 0.5 1.9 5.7 7.1 0.3 20.4 5.2 1.0 0.2 4.3 1.1 0.5 7.2 5.5 1.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.1 0.0 0.0 2.7 0.0 185.5 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 89.8 0.0 0.0 0.0 0.0 0.3 416.5 177.7 0.0 0.1 3.3 0.1 560.9 146.2 2.6 11.9 12.8 89.2 7.9 24.3 20.2 145.2 1.8 0.6 0.7 3.8 14.0 0.4 113.6 11.4 81.6 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.2 0.3 0.2 0.3 0.1 0.0 1.3 0.0 5.8 0.3 0.0 0.0 0.6 0.0 0.1 0.1 0.3 1.5 0.0 0.0 0.0 0.1 40.4 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 4.4 0.0 0.0 0.0 0.4 1.1 0.1 0.0 0.0 1.8 0.9 0.8 0.0 0.0 0.0 0.0 43.1 10.5 0.7 0.0 25.2 0.0 0.0 34.9 0.0 1.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 8.2 0.1 0.1 0.0 CCR3 "CC-CKR-3, CD193, CKR3, CMKBR3" ENSG00000183625 "C-C motif chemokine receptor 3" P51677 3 46163604-46266706 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.2;granulocytes: 1.3;Melanocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 25 "basophil: 3389.4;eosinophil: 2509.9" "Lineage enriched" "Detected in many" 109 "granulocytes: 3389.4" "Cell line enriched" "Detected in some" 10 "RPMI-8226: 29.6" "Not detected" "Not detected" "CAB003795, HPA069514" Uncertain Supported "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "CAB003795: AB_562259, HPA069514: " "unprognostic (1.56e-2)" "unprognostic (6.65e-3)" "unprognostic (1.01e-1)" "unprognostic (3.98e-2)" "unprognostic (1.41e-1)" "unprognostic (3.25e-3)" "unprognostic (3.11e-7)" "unprognostic (4.36e-2)" "unprognostic (3.35e-2)" "unprognostic (3.43e-2)" "unprognostic (4.81e-2)" "unprognostic (3.94e-2)" "unprognostic (3.17e-6)" "unprognostic (1.35e-2)" "unprognostic (1.72e-2)" "unprognostic (2.41e-1)" "unprognostic (9.81e-2)" 0.1 0.0 0.2 1.6 0.3 0.4 0.0 0.1 0.5 0.1 1.7 0.8 1.3 0.0 0.0 0.2 0.1 0.7 0.0 0.1 0.2 0.1 0.1 0.6 0.5 0.4 0.0 0.0 0.3 0.0 0.0 0.7 0.4 0.0 0.7 0.0 0.0 0.1 1.7 0.8 2.6 0.9 0.0 1.5 1.2 0.2 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 2.6 0.1 0.8 0.0 0.9 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.4 0.1 0.3 0.1 0.0 0.0 0.3 0.0 29.6 0.0 2.4 0.1 0.0 0.1 0.8 0.0 0.8 0.0 0.7 0.0 0.1 0.2 0.0 0.1 3.0 2.6 0.0 0.0 0.5 0.0 3389.4 1.0 2509.9 0.5 1.5 0.8 1.2 2.6 1.4 1.1 0.7 0.3 0.9 115.8 0.5 1.4 3.5 31.1 7.6 0.2 0.3 0.1 0.5 0.1 0.2 0.4 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 CCR4 "CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, k5-5" ENSG00000183813 "C-C motif chemokine receptor 4" P51679 3 32951644-32956349 "CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.0;urinary bladder: 5.4" "Cell type enhanced" "Detected in some" "granulocytes: 2.5;Horizontal cells: 5.0;Plasma cells: 2.1;Spermatogonia: 1.8;T-cells: 7.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "T-reg: 60.9" "Lineage enriched" "Detected in many" 41 "T-cells: 60.9" "Cell line enriched" "Detected in some" 17 "HDLM-2: 206.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031613 Approved Supported "Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "HPA031613: AB_10601096" "unprognostic (4.63e-3)" "unprognostic (8.70e-3)" "unprognostic (2.82e-3)" "unprognostic (2.64e-3)" "unprognostic (1.18e-1)" "unprognostic (4.59e-7)" "unprognostic (3.02e-1)" "unprognostic (5.05e-3)" "unprognostic (1.53e-2)" "unprognostic (1.69e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (9.88e-3)" "unprognostic (2.04e-1)" "unprognostic (5.53e-4)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" 0.5 0.2 0.3 8.6 0.3 1.7 0.6 0.8 0.7 0.6 0.2 0.9 0.6 0.4 0.3 1.2 0.2 3.3 0.2 0.4 0.4 0.3 0.6 1.7 7.0 0.2 0.1 0.2 0.3 0.2 0.0 0.1 0.4 0.8 1.2 0.1 0.5 0.1 2.0 2.1 1.5 0.6 0.0 3.2 1.4 0.8 0.2 13.0 0.3 0.1 8.0 5.4 0.2 0.7 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.3 0.4 0.2 0.1 0.0 0.0 0.3 0.0 0.1 0.0 206.5 0.0 12.2 0.7 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.2 0.0 5.8 3.2 0.8 0.0 0.0 1.8 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.5 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.4 0.3 0.2 0.1 0.2 0.2 0.2 0.0 1.4 0.3 0.3 0.4 0.3 0.4 0.3 11.5 3.4 0.1 0.4 0.3 0.3 1.1 0.3 0.3 0.4 60.9 1.7 0.3 0.3 0.8 0.7 0.4 0.4 0.2 0.1 0.4 0.0 0.2 0.7 0.1 0.0 0.6 0.0 0.4 0.4 0.7 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 2.5 0.0 0.4 0.1 0.1 5.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.7 0.8 0.0 0.5 0.2 0.0 1.8 0.0 0.1 0.0 7.8 0.0 0.0 0.6 CD109 "CPAMD7, DKFZp762L1111, FLJ38569" ENSG00000156535 "CD109 molecule" Q6YHK3 6 73695785-73828316 "CD markers, Plasma proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "parathyroid gland: 330.4" "Cell type enhanced" "Detected in many" "Adipocytes: 65.3;Basal respiratory cells: 62.8;Hofbauer cells: 45.0;Squamous epithelial cells: 51.4;Suprabasal keratinocytes: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 206.4;BJ hTERT+: 126.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008992, HPA015723" Enhanced Supported "Plasma membrane,Cytosol" NA NA 180000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA008992: , HPA015723: AB_2732415" "unprognostic (2.28e-1)" "unprognostic (1.03e-1)" "unprognostic (7.76e-2)" "unprognostic (1.52e-2)" "unprognostic (9.17e-3)" "unprognostic (1.36e-1)" "unprognostic (1.03e-3)" "unprognostic (1.23e-3)" "unprognostic (7.49e-2)" "unprognostic (2.47e-1)" "unprognostic (1.15e-3)" "unprognostic (8.81e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (7.96e-5)" "unprognostic (9.50e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (4.68e-4)" 8.6 1.1 2.3 2.4 2.5 2.8 5.5 2.1 2.1 9.9 0.7 6.9 1.3 12.5 5.6 10.2 3.2 4.1 5.8 2.0 4.0 7.0 1.1 6.6 1.0 3.2 3.6 0.7 0.5 330.4 0.4 6.5 3.5 3.6 2.9 0.2 3.4 2.5 1.2 18.9 2.2 12.6 3.7 2.1 1.1 1.8 2.5 3.1 1.3 3.3 2.2 4.5 7.4 3.1 35.6 29.4 1.5 0.1 48.2 206.4 0.0 30.5 126.0 9.0 18.4 0.1 20.2 0.0 19.7 63.5 19.5 96.5 3.5 60.9 12.1 8.5 5.5 11.5 21.0 5.8 10.1 0.0 0.3 60.7 52.4 18.6 68.7 34.2 71.6 3.9 0.0 0.2 45.0 0.8 0.8 0.0 2.4 0.3 18.9 2.6 8.4 40.6 4.8 3.6 0.0 0.1 68.6 0.7 30.8 1.3 0.8 5.8 68.7 96.8 10.1 17.2 28.5 0.7 17.9 0.1 40.3 0.1 89.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 2.3 2.5 2.1 2.1 2.0 4.0 3.2 3.6 3.5 3.7 2.5 3.1 65.3 3.2 1.7 39.8 1.1 41.4 8.4 62.8 35.9 0.3 2.2 2.2 13.0 0.0 16.3 0.0 0.0 0.4 1.2 0.1 1.9 0.1 23.4 10.8 10.5 38.0 0.0 7.6 4.0 0.0 0.5 25.0 0.5 15.0 2.5 0.0 21.0 0.6 45.0 0.0 3.3 0.1 4.1 2.7 28.5 21.0 0.6 13.5 23.2 19.7 3.3 0.0 0.0 1.5 1.0 0.4 0.0 0.0 1.7 10.8 0.0 23.5 16.0 0.2 0.0 7.4 13.2 1.0 3.5 51.4 43.8 1.4 4.6 1.4 0.2 7.2 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD180 "LY64, Ly78, RP105" ENSG00000134061 "CD180 molecule" Q99467 5 67179613-67196799 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.3" "Cell type enhanced" "Detected in some" "B-cells: 53.6;Hofbauer cells: 78.6;Kupffer cells: 23.5;Macrophages: 17.5;monocytes: 13.8;Plasma cells: 39.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 77.0;naive B-cell: 78.9" "Group enriched" "Detected in many" 25 "B-cells: 78.9;dendritic cells: 23.5;monocytes: 34.5" "Group enriched" "Detected in some" 10 "Daudi: 45.2;Karpas-707: 41.1;U-266/70: 33.1;U-266/84: 49.0;U-698: 12.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003740 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Mitotic spindle" Yes NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nucleoli, Mitotic spindle" "HPA003740: AB_1078450" "unprognostic (9.33e-2)" "unprognostic (4.58e-2)" "unprognostic (2.81e-3)" "unprognostic (5.85e-3)" "unprognostic (2.25e-2)" "unprognostic (4.04e-3)" "unprognostic (1.09e-1)" "unprognostic (4.95e-2)" "unprognostic (5.83e-2)" "unprognostic (3.71e-1)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.09e-1)" "unprognostic (1.16e-1)" "unprognostic (3.70e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" 1.6 0.7 0.7 9.7 0.7 2.4 6.7 0.6 1.2 0.5 0.4 2.1 2.0 0.5 0.2 0.4 0.4 1.6 0.4 0.8 0.7 0.3 2.5 1.6 23.2 1.5 1.5 0.2 0.3 0.2 0.1 3.2 2.0 0.5 2.7 0.3 1.1 0.4 0.1 0.2 3.9 1.8 1.0 12.9 2.2 0.4 1.8 2.5 0.3 0.2 23.3 3.0 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 41.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.6 0.2 33.1 49.0 12.3 0.0 2.7 0.0 0.3 11.8 0.9 0.0 20.4 0.0 77.0 0.1 0.1 22.1 78.9 0.0 0.0 0.9 1.8 34.5 23.5 0.1 8.5 0.7 0.7 0.6 1.2 0.8 0.7 1.5 1.5 2.0 1.0 1.8 2.1 0.1 0.0 0.5 0.3 53.6 0.4 0.1 0.0 0.0 0.1 1.8 1.1 0.7 1.5 0.0 0.0 0.0 0.4 4.0 0.0 0.0 0.0 2.2 0.1 0.0 0.6 0.0 1.7 0.0 0.2 0.3 0.4 0.0 0.1 2.5 0.0 0.0 0.3 78.6 0.0 0.0 0.0 0.0 23.5 8.0 1.0 0.0 17.5 0.0 1.9 13.8 0.1 0.0 0.0 0.0 0.3 0.0 0.0 39.6 0.0 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.7 2.2 0.0 0.1 0.1 CD2 SRBC ENSG00000116824 "CD2 molecule" P06729 1 116754430-116769229 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 249.8" "Group enriched" "Detected in many" 6 "dendritic cells: 158.3;NK-cells: 178.2;T-cells: 476.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 6 "gdT-cell: 421.8;MAIT T-cell: 403.1;memory CD4 T-cell: 610.2;memory CD8 T-cell: 714.1;naive CD4 T-cell: 316.3;naive CD8 T-cell: 486.2;NK-cell: 1108.0;T-reg: 655.2" "Group enriched" "Detected in all" 10 "NK-cells: 1108.0;T-cells: 714.1" "Group enriched" "Detected in some" 25 "HDLM-2: 224.1;JURKAT: 145.8;MOLT-4: 166.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002430, HPA003883" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "CAB002430: AB_442057, HPA003883: AB_1846263" "prognostic favorable (4.36e-4)" "prognostic favorable (1.47e-4)" "unprognostic (3.34e-3)" "prognostic favorable (1.69e-5)" "unprognostic (1.52e-1)" "prognostic favorable (7.46e-5)" "unprognostic (9.32e-3)" "unprognostic (1.61e-2)" "prognostic favorable (3.97e-5)" "prognostic favorable (7.72e-4)" "unprognostic (4.18e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (4.82e-6)" "unprognostic (6.16e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-2)" "unprognostic (7.63e-3)" 4.6 4.6 0.6 51.3 0.7 11.4 7.6 0.6 1.0 5.8 0.8 13.9 17.2 3.7 2.8 8.4 4.2 16.8 2.6 0.5 0.8 2.5 7.8 21.0 119.6 1.7 0.7 2.8 2.9 0.9 0.7 1.0 1.1 5.2 16.0 0.0 8.6 2.3 1.4 3.5 28.4 4.4 1.0 44.1 24.1 1.8 1.0 249.8 3.8 1.7 79.1 20.8 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 224.1 0.0 0.4 0.0 0.0 0.0 0.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 145.8 0.1 0.5 0.0 0.0 166.9 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.8 0.4 0.0 11.3 5.2 1.6 421.8 3.7 403.1 3.8 610.2 714.1 95.4 2.5 316.3 486.2 14.1 1108.0 2.8 21.0 655.2 565.1 0.6 0.7 0.6 1.0 0.5 0.8 1.7 0.7 1.1 1.0 1.0 1.1 5.0 3.2 17.5 0.0 12.3 5.0 0.4 0.0 2.2 0.0 4.0 4.7 2.1 0.0 2.5 3.7 0.0 0.1 158.3 0.2 0.0 0.5 23.5 1.1 1.0 2.9 3.0 24.0 0.0 0.0 0.0 2.5 10.7 0.9 5.1 0.0 8.2 1.5 0.6 0.0 0.0 0.0 0.0 10.9 16.6 7.8 0.6 19.1 1.8 1.0 15.5 0.0 178.2 0.0 0.0 0.0 0.0 0.4 42.3 0.1 0.0 1.7 0.0 0.0 0.0 2.9 4.1 0.3 0.2 0.4 3.7 0.0 476.8 0.0 0.5 0.2 CD200R1 "CD200R, HCRTR2, MOX2R, OX2R" ENSG00000163606 "CD200 receptor 1" Q8TD46 3 112921205-112975103 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 14.8;granulocytes: 15.2;Hepatic stellate cells: 14.6;Hofbauer cells: 31.8;Langerhans cells: 19.9;T-cells: 12.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "basophil: 234.9" "Lineage enriched" "Detected in all" 10 "granulocytes: 234.9" "Cell line enriched" "Detected in some" 8 "HEL: 25.5" HPA068512 Supported "Plasma membrane" "Intracellular and membrane" NA NA 2000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA068512: AB_2732784" "unprognostic (1.49e-2)" "unprognostic (1.06e-2)" "unprognostic (2.55e-1)" "unprognostic (1.97e-2)" "unprognostic (1.53e-1)" "unprognostic (1.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.06e-3)" "unprognostic (8.30e-2)" "unprognostic (1.85e-1)" "unprognostic (7.98e-2)" "unprognostic (2.46e-1)" "unprognostic (1.08e-5)" "unprognostic (1.77e-1)" "unprognostic (7.84e-3)" "unprognostic (1.25e-1)" "unprognostic (5.12e-3)" 1.7 1.2 0.3 3.0 0.4 1.7 1.4 0.2 0.6 0.7 0.7 1.5 1.6 0.7 0.3 3.8 0.5 1.9 0.6 0.4 0.3 0.5 2.4 1.9 4.4 0.3 0.2 0.3 0.5 0.5 0.2 5.3 0.3 0.6 2.3 0.1 0.6 0.7 0.1 2.6 2.0 1.1 0.2 7.9 1.5 0.7 0.2 3.4 0.5 0.9 4.6 1.9 0.5 0.2 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.3 25.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 1.2 0.0 234.9 2.9 53.6 4.0 1.3 7.0 9.9 13.8 7.9 22.9 5.6 13.4 6.1 0.8 2.5 0.4 0.5 4.3 5.2 0.3 0.4 0.2 0.6 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.2 0.2 0.0 1.1 1.6 4.4 1.9 0.1 0.0 14.8 0.0 0.2 0.3 0.3 0.0 0.1 0.0 0.0 0.3 1.9 0.0 0.0 0.0 0.1 1.0 0.1 0.5 0.0 4.0 5.7 0.0 0.2 0.9 0.0 0.1 15.2 0.0 14.6 0.1 31.8 0.0 2.2 0.0 0.0 6.7 19.9 0.0 0.0 9.1 5.4 5.6 5.2 0.0 0.0 1.0 0.7 0.1 0.0 0.0 2.7 0.1 0.0 0.1 1.2 0.0 0.0 0.3 0.4 0.8 0.3 5.8 0.9 0.7 12.4 0.0 0.0 0.2 CD226 "DNAM-1, DNAM1, PTA1, TLiSA1" ENSG00000150637 "CD226 molecule" Q15762 18 69831158-69961803 "CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 20.2;parathyroid gland: 62.4" "Cell type enhanced" "Detected in many" "dendritic cells: 52.1;Macrophages: 24.4;Microglial cells: 22.5;NK-cells: 90.6;Oligodendrocytes: 26.6;T-cells: 43.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 36.6;MAIT T-cell: 13.4;memory CD4 T-cell: 28.8;memory CD8 T-cell: 22.5;naive CD4 T-cell: 15.8;naive CD8 T-cell: 17.3;NK-cell: 29.7;T-reg: 11.3" "Group enriched" "Detected in many" 11 "NK-cells: 29.7;T-cells: 36.6" "Group enriched" "Detected in some" 6 "HEL: 100.0;HMC-1: 42.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA015715, HPA015865" Supported Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" NA No 20000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA015715: AB_1846278, HPA015865: " "unprognostic (1.42e-4)" "unprognostic (1.30e-3)" "unprognostic (9.01e-3)" "unprognostic (3.49e-5)" "unprognostic (4.15e-1)" "unprognostic (9.52e-4)" "unprognostic (3.68e-3)" "unprognostic (2.93e-2)" "unprognostic (3.43e-1)" "unprognostic (3.31e-3)" "unprognostic (8.36e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-3)" "unprognostic (2.20e-1)" "unprognostic (3.91e-2)" "unprognostic (2.27e-1)" "unprognostic (3.58e-2)" 1.1 0.6 1.1 5.7 6.4 4.4 1.5 1.5 2.4 1.1 0.0 1.8 2.3 1.3 0.5 1.6 1.3 3.0 0.5 0.7 2.0 1.5 4.2 4.2 9.7 3.1 3.3 0.9 0.5 62.4 0.6 0.5 3.2 1.0 2.4 1.4 1.5 0.4 0.7 0.3 3.1 1.6 2.2 20.2 3.2 1.2 5.5 6.4 0.7 0.6 7.1 3.1 0.4 3.2 0.0 0.1 0.3 0.3 0.0 0.0 0.1 0.6 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.4 0.2 5.3 0.1 100.0 0.3 0.1 0.0 0.7 42.6 0.0 1.1 0.2 0.6 0.2 0.0 0.9 0.3 9.3 0.4 0.0 0.8 0.4 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.5 0.8 0.3 0.1 0.2 11.5 0.4 0.0 0.3 0.2 0.5 0.3 0.1 1.2 36.6 1.0 13.4 0.8 28.8 22.5 2.9 0.1 15.8 17.3 1.6 29.7 1.3 0.1 11.3 13.2 1.1 6.4 1.5 2.4 0.7 2.0 3.1 3.3 3.2 2.2 5.5 3.2 0.6 3.2 3.6 3.3 3.2 0.0 0.3 0.0 0.0 3.4 0.5 0.8 2.5 0.0 0.7 0.0 0.0 0.1 52.1 0.2 0.0 0.0 8.4 0.9 1.7 1.0 0.0 3.2 4.6 0.4 0.0 1.3 3.1 0.5 13.9 1.3 3.3 0.4 1.6 0.0 3.1 0.1 0.0 16.7 2.7 8.2 0.9 24.4 0.0 22.5 14.7 0.8 90.6 2.0 26.6 0.2 0.1 0.7 13.4 0.3 0.0 0.3 1.5 3.6 0.0 1.8 0.6 0.4 0.8 0.0 0.4 0.0 43.2 0.5 0.1 0.2 CD274 "B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1" ENSG00000120217 "CD274 molecule" Q9NZQ7 9 5450503-5470566 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 27.7;granulocytes: 28.4;Langerhans cells: 50.9;monocytes: 42.4;Syncytiotrophoblasts: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.6" "Cell line enhanced" "Detected in many" "HDLM-2: 89.6;HHSteC: 55.5;U-251 MG: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003528, CAB076385" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Actin filaments" Nucleoplasm "CAB076385: AB_2687655, HPA003528: " "prognostic favorable (8.89e-4)" "unprognostic (4.54e-2)" "prognostic favorable (1.64e-5)" "unprognostic (1.27e-2)" "unprognostic (2.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (5.67e-4)" "unprognostic (7.39e-3)" "unprognostic (1.69e-2)" "unprognostic (1.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-2)" "unprognostic (2.67e-1)" "unprognostic (9.02e-2)" 2.6 2.0 1.0 10.3 0.9 1.9 1.5 0.9 1.2 1.8 0.6 1.4 2.7 1.5 1.8 2.5 1.8 4.0 8.9 0.8 1.9 2.6 3.4 16.8 6.6 1.8 1.6 1.5 1.9 5.0 2.6 6.8 2.0 2.0 2.1 1.2 1.5 1.5 4.5 0.7 1.9 2.2 1.7 10.2 1.9 0.9 1.6 13.0 3.5 4.3 5.3 7.2 1.3 1.1 15.6 0.2 0.0 0.5 0.1 0.1 0.0 30.5 25.7 7.7 10.4 0.0 5.0 0.2 0.6 0.8 3.8 0.6 0.0 13.2 24.6 89.6 0.0 9.0 0.3 0.0 55.5 0.0 0.0 0.5 0.1 15.7 22.9 7.7 15.0 0.9 0.0 2.9 23.4 0.0 0.4 0.1 0.0 0.0 0.3 0.1 4.2 0.8 1.6 0.3 0.0 0.3 0.4 2.4 1.9 2.2 0.1 0.3 28.1 16.1 5.1 0.5 98.1 0.5 0.2 0.3 5.4 0.3 0.2 6.6 0.0 0.2 0.7 0.1 1.2 0.5 1.4 1.1 0.0 0.1 0.7 0.4 3.6 0.3 0.0 0.0 0.7 0.4 1.0 0.9 0.9 1.2 0.8 1.9 1.8 1.6 2.0 1.7 1.6 1.1 3.0 12.8 11.4 0.7 1.9 4.6 1.5 4.4 1.8 1.4 1.4 1.3 7.8 0.0 2.9 0.0 0.0 6.1 2.4 2.6 0.0 5.9 1.0 1.4 0.3 5.5 0.0 3.2 1.9 4.4 27.7 1.9 0.5 0.9 28.4 0.2 7.1 0.8 5.7 0.0 3.3 0.5 4.1 2.9 50.9 0.2 0.3 4.2 3.6 8.4 42.4 0.5 1.0 1.0 0.9 19.0 0.1 0.4 2.2 2.1 1.9 0.4 4.0 0.2 0.0 2.3 0.9 1.0 0.8 1.2 2.6 44.5 3.1 0.1 0.4 2.0 CD2AP CMS ENSG00000198087 "CD2 associated protein" Q9Y5K6 6 47477789-47627263 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 204.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003267, HPA003326, CAB004352" Enhanced Supported "Plasma membrane,Centriolar satellite" NA NA 58000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Centriolar satellite" "CAB004352: AB_627009, HPA003267: AB_1078458, HPA003326: AB_1078457" "unprognostic (5.98e-2)" "unprognostic (1.08e-2)" "unprognostic (1.75e-2)" "unprognostic (1.74e-1)" "unprognostic (1.31e-1)" "unprognostic (1.77e-2)" "unprognostic (1.74e-3)" "unprognostic (1.19e-1)" "unprognostic (6.71e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (5.53e-5)" "unprognostic (2.21e-1)" "unprognostic (3.09e-3)" "unprognostic (6.12e-3)" "unprognostic (1.74e-1)" "unprognostic (1.84e-1)" "prognostic favorable (7.57e-5)" 14.0 10.5 3.4 15.0 3.4 14.3 17.8 6.3 4.6 18.1 8.8 40.0 56.9 12.0 13.2 19.2 14.1 15.0 7.7 2.7 3.8 34.1 20.2 17.1 15.9 4.3 3.9 6.4 20.2 35.6 6.0 21.6 4.7 19.7 36.9 6.9 17.0 13.5 6.9 18.0 59.5 10.9 4.3 13.7 40.4 9.4 3.9 34.0 18.2 10.3 17.4 30.1 10.1 4.6 58.0 22.5 6.9 14.3 9.4 13.6 54.8 13.9 16.9 18.5 23.3 37.3 39.9 74.5 56.9 18.2 24.0 21.2 23.0 34.7 29.9 29.9 37.2 41.3 18.4 33.6 12.5 23.3 15.4 9.7 32.1 17.7 25.5 35.7 30.1 24.4 73.5 23.2 16.9 18.2 44.6 8.7 20.3 69.6 8.1 23.6 17.6 34.1 115.6 101.7 20.9 8.1 27.9 36.9 27.7 31.1 35.0 14.8 36.2 36.9 30.8 12.0 39.9 17.5 31.3 52.6 39.4 12.4 19.2 1.8 0.5 3.2 1.2 0.4 1.8 0.9 1.0 1.1 1.2 1.0 0.9 1.5 0.1 3.1 0.4 9.9 0.9 0.5 3.4 3.4 6.3 4.6 2.7 3.8 4.3 3.9 4.7 4.3 3.9 4.6 81.7 96.1 67.1 32.0 40.5 32.2 52.1 26.5 39.9 10.0 40.4 26.4 17.2 35.8 68.9 71.7 16.7 53.0 96.1 204.1 21.5 84.6 10.4 97.9 25.0 56.6 55.8 42.9 40.7 98.0 17.1 20.6 101.4 136.7 24.1 28.5 37.5 24.2 17.4 15.2 45.3 97.3 40.7 26.2 12.6 10.5 16.8 30.6 14.2 83.4 18.0 12.5 22.6 28.6 30.8 151.3 114.0 10.9 27.7 89.0 182.3 67.4 60.0 13.0 26.3 34.9 27.8 38.9 27.2 44.2 41.1 40.9 29.4 48.0 68.8 143.6 CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4;lymphoid tissue: 23.9" "Group enriched" "Detected in some" 6 "granulocytes: 76.0;Hofbauer cells: 78.8;Kupffer cells: 131.2;Langerhans cells: 41.4;Macrophages: 53.5;monocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.5;intermediate monocyte: 122.0;myeloid DC: 213.5;non-classical monocyte: 57.8" "Group enriched" "Detected in many" 9 "dendritic cells: 213.5;monocytes: 166.5" "Cell line enhanced" "Detected in some" "HEL: 86.1;HL-60: 115.6;HMC-1: 82.4;NB-4: 55.2;RPMI-8226: 62.5;THP-1: 67.0;U-937: 84.1" "CAB011442, HPA035832, HPA064807, CAB079996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 3400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane" "CAB011442: , CAB079996: , HPA035832: AB_2674808, HPA064807: AB_2685356" "unprognostic (1.18e-2)" "unprognostic (1.45e-2)" "unprognostic (2.80e-2)" "unprognostic (7.14e-2)" "unprognostic (3.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.53e-1)" "unprognostic (6.28e-2)" "unprognostic (6.88e-4)" "unprognostic (7.79e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" "unprognostic (1.67e-1)" 7.9 3.4 1.1 11.2 1.2 32.4 2.5 1.5 1.6 3.0 2.5 3.2 3.3 1.7 1.3 2.0 2.5 6.6 2.0 1.1 1.8 1.4 5.5 12.6 10.1 2.5 1.6 1.4 1.4 1.2 0.9 6.9 2.4 1.4 4.2 0.2 1.8 2.6 0.9 2.7 4.4 7.1 1.9 23.9 2.3 1.0 2.3 3.5 0.9 0.8 3.5 6.2 1.3 3.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.0 5.5 0.4 0.0 1.3 0.3 0.0 0.2 0.0 0.1 0.1 86.1 0.3 0.0 0.0 115.6 82.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 16.2 21.2 0.2 0.0 0.0 55.2 0.2 0.0 25.9 0.0 4.4 62.5 0.4 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 67.0 0.7 14.0 1.1 1.8 0.1 0.3 7.6 0.2 9.6 84.1 0.4 17.9 166.5 11.0 0.3 122.0 0.4 0.1 0.2 0.5 213.5 0.4 0.3 0.2 20.5 15.5 57.8 6.3 1.1 77.8 1.1 1.2 1.5 1.6 1.1 1.8 2.5 1.6 2.4 1.9 2.3 3.6 0.7 0.0 6.7 0.0 1.0 1.8 0.5 0.0 0.0 0.2 1.4 0.4 0.8 0.0 0.6 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.7 0.1 0.1 3.0 0.0 4.2 0.0 0.0 0.5 1.1 0.0 0.1 76.0 0.1 5.3 0.7 78.8 0.0 0.0 0.0 0.0 131.2 41.4 1.7 0.3 53.5 1.8 11.2 65.0 0.2 1.0 0.5 0.2 0.0 0.0 0.0 0.3 0.4 0.0 0.2 0.7 0.6 0.0 1.1 0.3 0.7 0.5 0.0 1.0 0.8 2.5 0.1 0.0 0.4 CD38 ENSG00000004468 "CD38 molecule" P28907 4 15778275-15853232 "Cancer-related genes, CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Receptor, Transferase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 63.3" "Cell type enriched" "Detected in many" 4 "Plasma cells: 378.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 18.3" "Group enriched" "Detected in all" 5 "B-cells: 9.9;dendritic cells: 5.8;NK-cells: 18.3" "Cell line enhanced" "Detected in some" "Daudi: 128.0;Karpas-707: 34.7;MOLT-4: 32.6;REH: 26.0;RPMI-8226: 20.9;U-266/70: 26.9;U-698: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002493, HPA022132, CAB025255, HPA052381" Enhanced Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" "CAB002493: AB_563556, CAB025255: , HPA022132: AB_1846300, HPA052381: AB_2681807" "unprognostic (1.27e-2)" "unprognostic (8.06e-3)" "unprognostic (1.06e-2)" "prognostic favorable (9.68e-4)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (2.74e-1)" "unprognostic (8.51e-2)" "unprognostic (5.87e-2)" "unprognostic (6.15e-6)" "unprognostic (5.23e-1)" "unprognostic (4.34e-1)" "unprognostic (6.63e-6)" "unprognostic (1.79e-1)" "unprognostic (5.74e-2)" "unprognostic (2.12e-2)" "unprognostic (2.13e-1)" 3.1 2.4 2.5 13.1 3.8 13.6 2.0 2.7 2.5 0.7 0.9 4.5 5.8 0.9 1.2 1.1 3.0 1.9 3.8 3.5 6.6 0.8 3.3 6.3 23.4 3.3 5.5 0.7 0.3 0.1 1.8 0.5 3.4 13.2 3.5 0.2 2.6 19.7 21.4 0.3 5.3 1.4 2.8 17.0 3.0 1.0 3.9 63.3 2.0 3.4 18.0 6.8 0.5 4.6 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 128.0 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 17.0 0.2 34.7 0.0 0.0 32.6 7.9 0.2 0.0 0.0 26.0 0.1 20.9 0.0 0.0 0.2 1.5 0.0 0.2 0.5 0.3 0.1 5.7 0.5 0.0 0.1 0.1 0.0 26.9 0.2 24.3 0.4 6.2 0.3 0.1 1.9 0.1 1.2 2.4 0.3 9.9 1.5 1.2 4.7 7.7 2.4 1.9 1.4 18.3 1.9 5.8 2.4 4.4 2.5 3.8 2.7 2.5 3.5 6.6 3.3 5.5 3.4 2.8 3.9 4.6 0.8 3.2 15.1 86.5 59.7 0.0 0.4 0.6 0.6 0.1 0.1 0.0 1.0 0.0 11.6 0.0 10.4 0.2 33.8 0.2 0.0 0.0 2.5 4.0 1.4 2.7 0.0 78.6 0.4 0.0 0.2 2.7 2.0 0.3 38.2 0.8 2.9 4.3 4.4 0.0 0.4 1.3 0.0 44.3 0.8 0.7 0.0 17.7 7.2 5.6 3.1 0.0 79.3 1.0 1.8 0.0 0.3 0.0 378.4 8.1 0.2 0.1 42.5 0.1 13.1 1.5 7.6 2.9 1.7 1.6 0.0 0.5 26.5 0.0 1.6 0.2 CD3E ENSG00000198851 "CD3e molecule" P07766 11 118304730-118316175 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "lymphoid tissue: 640.4" "Group enriched" "Detected in many" 7 "dendritic cells: 213.6;NK-cells: 154.5;T-cells: 601.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 26 "gdT-cell: 490.6;MAIT T-cell: 420.8;memory CD4 T-cell: 414.4;memory CD8 T-cell: 463.5;naive CD4 T-cell: 491.7;naive CD8 T-cell: 501.3;NK-cell: 202.2;T-reg: 426.3" "Group enriched" "Detected in all" 21 "NK-cells: 202.2;T-cells: 501.3" "Group enriched" "Detected in some" 67 "JURKAT: 544.9;MOLT-4: 764.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000010, HPA040957, HPA043955, CAB072863, CAB072864" Enhanced Supported "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Endoplasmic reticulum, Plasma membrane" "Golgi apparatus" "CAB000010: AB_2631163, CAB072863: AB_2665707, CAB072864: AB_2665708, HPA040957: AB_2677222, HPA043955: AB_2678747" "prognostic favorable (1.72e-4)" "prognostic favorable (1.62e-4)" "unprognostic (1.51e-2)" "prognostic favorable (2.30e-6)" "unprognostic (4.31e-2)" "prognostic favorable (1.32e-4)" "unprognostic (3.60e-3)" "unprognostic (3.85e-2)" "prognostic favorable (1.18e-4)" "unprognostic (6.11e-3)" "unprognostic (1.59e-1)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (5.46e-2)" "unprognostic (9.28e-2)" "unprognostic (3.13e-2)" "unprognostic (1.12e-2)" 6.4 5.6 0.9 85.8 1.1 36.7 6.7 0.9 1.2 7.1 1.3 15.3 22.0 5.8 4.6 9.5 5.4 20.1 3.8 0.7 1.0 3.5 9.7 23.0 209.6 1.8 0.9 3.8 2.2 0.7 1.0 1.6 1.4 6.6 19.3 0.0 11.6 3.0 1.9 5.4 36.4 5.1 1.2 78.9 24.4 1.7 1.3 640.4 5.3 1.6 147.0 24.8 4.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 544.9 0.9 2.0 0.0 0.0 764.9 0.6 0.3 0.0 0.0 0.2 0.1 1.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 1.6 8.0 9.8 0.0 0.6 0.0 16.4 1.8 2.4 490.6 1.3 420.8 1.6 414.4 463.5 1.5 2.1 491.7 501.3 12.2 202.2 2.0 8.6 426.3 333.0 0.9 1.1 0.9 1.2 0.7 1.0 1.8 0.9 1.4 1.2 1.3 1.6 4.9 0.0 8.6 0.0 12.9 5.2 0.3 0.0 0.0 0.0 3.8 4.8 0.3 0.0 0.6 1.8 0.0 0.2 213.6 0.4 0.0 0.2 7.0 0.5 0.9 2.5 0.0 6.9 0.1 0.0 0.0 5.3 24.5 0.9 7.6 0.0 8.9 2.4 0.3 0.0 0.1 0.0 0.0 7.6 8.3 0.2 0.0 12.6 12.4 1.0 8.4 0.0 154.5 0.0 0.1 0.0 1.1 0.0 41.4 0.1 0.2 2.1 0.0 0.0 0.0 1.3 2.7 0.0 0.0 1.6 5.4 0.3 601.4 0.0 0.6 0.3 CD3G ENSG00000160654 "CD3g molecule" P09693 11 118344344-118355161 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 94.7" "Group enriched" "Detected in many" 11 "dendritic cells: 139.6;T-cells: 294.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 21 "gdT-cell: 229.0;MAIT T-cell: 135.6;memory CD4 T-cell: 187.3;memory CD8 T-cell: 197.3;naive CD4 T-cell: 192.6;naive CD8 T-cell: 241.7;T-reg: 200.0" "Lineage enriched" "Detected in many" 26 "T-cells: 241.7" "Group enriched" "Detected in some" 52 "JURKAT: 70.9;MOLT-4: 193.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017520, HPA038494" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "CAB017520: AB_831094, HPA038494: AB_2676044" "prognostic favorable (6.33e-4)" "prognostic favorable (2.61e-4)" "unprognostic (4.58e-3)" "unprognostic (3.12e-5)" "unprognostic (6.30e-2)" "prognostic favorable (3.00e-4)" "unprognostic (1.98e-2)" "unprognostic (1.54e-2)" "unprognostic (8.25e-3)" "unprognostic (1.08e-3)" "unprognostic (1.54e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (9.33e-5)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (4.13e-2)" "unprognostic (2.10e-3)" 0.7 0.8 0.6 10.5 0.8 1.3 1.0 1.1 0.8 0.7 1.1 2.3 3.3 0.5 0.6 1.4 0.9 2.5 0.5 0.5 0.4 0.6 1.6 2.8 27.9 0.9 0.6 0.4 0.5 0.2 0.0 0.3 0.8 0.9 2.7 0.4 1.6 0.3 10.5 0.9 4.6 0.6 0.3 11.5 4.1 0.4 0.8 94.7 0.6 0.3 20.4 3.0 0.4 1.9 0.2 0.2 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.2 0.7 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.6 0.0 0.4 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 70.9 2.5 0.3 0.0 0.6 193.8 1.3 0.2 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.5 0.2 0.0 1.1 0.1 0.0 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.2 0.7 0.3 0.2 0.2 0.1 9.2 1.2 1.2 229.0 0.6 135.6 0.8 187.3 197.3 0.6 0.9 192.6 241.7 6.4 1.4 1.2 1.5 200.0 90.4 0.6 0.8 1.1 0.8 0.5 0.4 0.9 0.6 0.8 0.3 0.8 1.9 3.2 3.2 6.9 0.0 7.8 2.3 0.1 0.0 1.8 0.2 2.0 2.9 0.8 1.5 1.9 0.0 0.0 0.1 139.6 0.4 0.0 0.3 1.0 0.4 0.4 1.4 0.0 3.4 0.1 0.0 0.0 2.3 13.7 0.4 6.3 0.0 4.2 1.7 0.1 0.0 0.1 0.2 0.0 3.8 5.8 1.4 0.0 7.7 5.4 1.0 8.1 0.0 14.4 0.0 0.3 0.0 0.1 0.0 18.5 0.0 0.0 0.6 0.7 0.8 0.0 1.3 1.6 0.2 0.4 0.6 2.4 0.3 294.0 0.1 0.3 0.0 CD40LG "CD154, CD40L, gp39, hCD40L, HIGM1, IMD3, TNFSF5, TRAP" ENSG00000102245 "CD40 ligand" P29965 X 136648158-136660390 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 15.5" "Cell type enriched" "Detected in some" 8 "T-cells: 76.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 26.3;MAIT T-cell: 64.1;memory CD4 T-cell: 80.5;naive CD4 T-cell: 76.1" "Lineage enriched" "Detected in many" 39 "T-cells: 80.5" "Cell line enriched" "Detected in some" 15 "MOLT-4: 23.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045827, HPA072480" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 776000 20000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus, Plasma membrane" "HPA045827: AB_10959606, HPA072480: " "unprognostic (1.94e-5)" "unprognostic (1.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.27e-3)" "unprognostic (4.71e-2)" "unprognostic (3.56e-5)" "unprognostic (3.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.77e-1)" "unprognostic (2.14e-4)" "unprognostic (1.87e-1)" "unprognostic (1.55e-1)" "unprognostic (6.70e-4)" "unprognostic (2.15e-1)" "unprognostic (5.19e-2)" "unprognostic (2.36e-3)" "unprognostic (2.92e-2)" 0.8 0.3 0.1 7.9 0.0 1.9 1.1 0.2 0.2 0.9 0.2 1.9 1.8 0.3 0.2 1.0 0.4 2.0 0.2 0.1 0.2 0.4 1.0 2.4 15.5 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.2 0.8 3.1 0.0 0.6 0.3 0.1 0.6 3.8 0.6 0.0 4.9 2.0 0.3 0.1 15.5 0.5 0.2 14.8 2.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.3 26.3 0.1 64.1 0.1 80.5 11.7 0.2 0.0 76.1 0.7 1.3 0.8 0.1 0.1 10.5 13.6 0.1 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.0 0.1 0.2 0.6 0.0 2.4 0.0 2.4 1.3 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.0 0.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 1.7 0.0 0.0 0.0 0.6 2.6 0.0 1.3 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.6 4.0 8.9 0.0 2.9 1.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.1 2.0 0.0 76.6 0.0 0.0 0.1 CD44 "CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1" ENSG00000026508 "CD44 molecule (Indian blood group)" P16070 11 35138882-35232402 "Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Blood group antigen, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 504.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 999.7;Ductal cells: 992.1;Exocrine glandular cells: 869.6;Langerhans cells: 1934.2;Suprabasal keratinocytes: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 1650.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000112, CAB000316, HPA005785" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 1200000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Golgi apparatus" "CAB000112: , CAB000316: AB_2076596, HPA005785: AB_1078467" "unprognostic (5.33e-2)" "unprognostic (1.85e-1)" "unprognostic (4.97e-2)" "unprognostic (9.90e-3)" "unprognostic (3.50e-3)" "unprognostic (1.46e-2)" "unprognostic (1.56e-2)" "unprognostic (8.12e-2)" "unprognostic (1.57e-1)" "unprognostic (4.18e-2)" "unprognostic (1.51e-3)" "unprognostic (4.63e-2)" "prognostic unfavorable (1.78e-8)" "unprognostic (6.41e-2)" "unprognostic (4.14e-2)" "unprognostic (3.93e-2)" "unprognostic (7.98e-2)" 143.7 42.4 29.2 218.0 33.9 308.1 164.7 63.0 25.1 146.0 16.8 91.1 53.0 200.4 20.1 227.8 69.0 129.7 30.4 33.0 116.5 31.3 31.0 214.1 108.8 114.9 102.3 11.7 263.2 6.0 8.1 74.1 118.3 87.3 111.5 38.0 504.2 57.0 17.1 433.3 60.8 175.8 114.3 83.8 61.5 6.6 62.8 64.2 76.2 27.7 188.7 235.2 193.4 114.9 493.0 448.6 4.3 1.2 252.6 691.5 1.6 962.2 740.3 521.3 288.2 30.4 150.4 0.7 126.5 1350.2 1065.4 820.1 9.9 1013.9 716.4 110.3 6.2 18.9 198.3 0.3 262.3 254.6 1124.3 315.4 778.3 693.2 552.7 1650.0 184.3 0.1 4.0 157.9 518.9 3.0 25.6 166.9 9.8 8.7 136.4 1.4 89.3 7.5 777.4 138.1 2.0 1.4 185.2 5.5 462.8 38.6 25.7 15.1 547.3 646.6 120.0 815.8 1006.0 281.6 327.7 3.7 980.4 145.1 969.8 127.4 403.0 35.4 140.6 257.8 196.5 122.5 210.1 186.5 229.0 90.0 179.7 153.6 92.6 322.3 356.1 79.9 309.7 437.3 29.2 33.9 63.0 25.1 33.0 116.5 114.9 102.3 118.3 114.3 62.8 114.9 41.0 96.1 361.8 54.5 250.1 999.7 297.7 335.3 228.2 0.6 139.6 71.2 8.6 27.1 125.6 20.2 2.1 4.5 257.0 14.0 1.9 992.1 41.3 43.6 395.4 50.9 100.1 94.4 0.4 869.6 3.6 282.2 39.8 196.9 763.2 25.2 13.2 3.6 226.6 0.0 0.4 93.3 30.5 474.3 1934.2 24.3 22.4 523.9 604.7 8.4 594.2 29.6 62.8 0.5 11.2 813.1 10.9 0.4 216.3 386.7 6.0 1.6 18.8 2.0 157.8 197.2 227.9 0.4 0.4 279.3 1024.9 17.9 430.8 1.0 79.1 330.7 CD47 "IAP, MER6, OA3" ENSG00000196776 "CD47 molecule" Q08722 3 108043091-108091862 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 589.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016055, HPA044659" Approved Supported "Vesicles,Plasma membrane" NA NA 49000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Vesicles "CAB016055: AB_627086, HPA044659: AB_2679040" "unprognostic (3.54e-2)" "unprognostic (4.74e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (2.44e-4)" "unprognostic (4.49e-2)" "unprognostic (2.14e-1)" "unprognostic (2.05e-3)" "unprognostic (8.77e-3)" "unprognostic (7.35e-2)" "unprognostic (1.53e-1)" "unprognostic (1.69e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (7.37e-2)" "unprognostic (3.78e-1)" "prognostic favorable (7.29e-5)" "unprognostic (1.83e-1)" 51.8 64.9 39.2 116.4 47.9 232.2 89.3 64.4 63.5 57.4 30.4 89.0 74.6 53.0 92.4 93.9 100.5 86.7 59.5 47.2 41.9 44.4 71.4 154.6 137.9 53.1 40.5 46.1 41.5 27.2 34.6 80.1 48.5 122.2 99.3 285.7 105.3 55.7 57.9 59.8 79.3 55.4 50.9 100.1 104.2 59.0 49.2 79.1 91.2 22.8 161.7 110.1 52.4 76.4 303.3 49.9 108.0 62.1 130.3 122.6 147.9 106.0 139.4 70.8 126.0 2.1 159.1 129.6 180.0 90.7 216.5 201.0 52.2 98.7 91.7 81.5 35.8 311.6 45.9 3.9 73.8 227.4 467.6 85.7 58.1 71.6 53.6 118.5 73.4 132.6 85.1 323.6 108.5 148.1 268.5 77.0 46.7 298.4 133.6 154.2 69.3 187.8 185.3 115.8 69.7 37.9 63.6 111.7 124.4 56.5 227.4 85.8 76.5 210.9 40.9 120.7 79.4 124.2 100.8 208.0 131.5 119.8 65.6 185.2 119.2 232.8 178.1 244.2 155.6 191.6 209.7 192.0 181.6 188.7 149.2 169.0 145.4 232.6 339.2 133.3 334.5 296.9 39.2 47.9 64.4 63.5 47.2 41.9 53.1 40.5 48.5 50.9 49.2 76.4 72.3 368.6 157.4 98.6 192.9 165.3 311.7 504.4 101.3 102.9 119.0 93.1 51.9 110.1 205.7 93.8 95.9 169.9 218.6 36.5 15.6 589.6 81.5 157.2 17.0 76.5 63.8 112.6 219.2 412.5 85.5 119.1 36.2 120.4 57.7 250.0 83.6 34.2 186.4 122.8 129.3 70.8 148.5 79.6 200.7 52.2 34.2 121.5 117.4 39.4 100.5 51.7 219.4 107.1 150.4 344.7 92.6 48.5 143.8 439.0 53.7 16.3 162.2 229.7 65.7 47.1 85.4 111.5 19.6 97.1 140.1 121.2 160.8 80.6 94.3 321.3 CD79B "B29, IGB" ENSG00000007312 "CD79b molecule" P40259 17 63928740-63932336 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 266.7" "Cell type enriched" "Detected in many" 4 "B-cells: 491.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "memory B-cell: 1132.1;naive B-cell: 1505.8" "Lineage enriched" "Detected in all" 5 "B-cells: 1505.8" "Cell line enhanced" "Detected in some" "Daudi: 1060.0;REH: 350.2;U-698: 1475.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009178, CAB009751, HPA044107" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB009751: AB_2275844, HPA009178: AB_1078483, HPA044107: " "unprognostic (3.90e-3)" "unprognostic (1.61e-3)" "unprognostic (5.21e-2)" "unprognostic (3.45e-3)" "unprognostic (4.22e-3)" "prognostic favorable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (9.25e-3)" "unprognostic (3.89e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (2.87e-2)" "unprognostic (2.50e-3)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (4.28e-2)" "unprognostic (2.75e-1)" 5.0 1.7 0.9 70.5 0.9 54.6 3.4 0.9 1.4 1.9 1.7 7.7 4.7 1.4 1.6 2.6 1.5 6.8 12.3 0.9 0.9 4.7 3.4 4.9 266.7 1.0 0.9 0.6 0.7 0.7 25.3 3.8 0.9 2.5 7.2 0.0 7.8 0.8 3.4 2.4 66.2 2.6 0.9 147.7 10.7 1.0 1.0 27.1 4.1 5.8 208.4 13.4 2.2 1.0 1.8 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.4 0.0 0.0 1060.0 7.8 0.0 0.4 0.3 0.0 0.0 0.0 0.5 0.0 2.7 0.0 0.4 0.6 0.6 0.5 0.0 0.0 0.1 0.0 0.0 1.2 0.4 1.2 56.9 0.0 0.0 0.6 23.0 0.3 0.0 0.0 350.2 0.9 4.4 0.0 0.0 0.5 0.0 1.7 0.0 0.7 5.8 0.0 16.2 1.7 0.1 3.7 0.3 0.6 51.3 54.4 1475.5 0.0 2.2 0.0 6.2 13.0 1.1 44.9 192.2 51.3 1132.1 57.1 30.1 47.0 1505.8 38.4 23.2 5.8 42.4 304.3 6.7 107.9 112.1 0.9 0.9 0.9 1.4 0.9 0.9 1.0 0.9 0.9 0.9 1.0 1.0 24.9 0.0 1.3 0.0 491.9 4.5 0.4 0.0 1.8 0.0 1.1 4.4 1.4 1.5 0.0 0.0 0.0 0.2 24.2 0.3 0.0 0.1 0.6 0.3 1.0 25.2 1.2 8.6 0.0 0.0 0.4 3.3 0.5 0.3 15.2 0.0 51.4 1.3 5.8 0.0 0.0 0.4 0.0 14.8 5.1 1.4 1.2 13.4 21.4 0.0 14.3 0.0 36.0 0.0 0.0 0.0 0.1 1.9 99.6 0.4 0.0 1.0 0.0 0.0 0.0 4.4 5.4 1.2 0.3 0.7 3.1 0.4 27.0 0.5 0.8 0.2 CD81 "TAPA-1, TAPA1, TSPAN28" ENSG00000110651 "CD81 molecule" P60033 11 2376177-2397397 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 1003.1;Endometrial stromal cells: 1050.9;Muller glia cells: 809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 148.9;naive B-cell: 137.2" "Lineage enriched" "Detected in all" 4 "B-cells: 148.9" "Cell line enhanced" "Detected in many" "ASC diff: 2960.6;fHDF/TERT166: 1752.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002507, HPA007234" Supported Supported "Plasma membrane,Cytosol" NA NA 400000 "Cluster 43: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Cytosol "CAB002507: AB_563639, HPA007234: AB_1846333" "unprognostic (2.96e-1)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.56e-4)" "unprognostic (1.84e-2)" "prognostic unfavorable (8.21e-5)" "unprognostic (6.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (3.86e-4)" "unprognostic (3.07e-3)" "unprognostic (2.08e-1)" "unprognostic (3.55e-2)" "unprognostic (1.67e-1)" "unprognostic (2.06e-1)" "unprognostic (2.06e-1)" 892.1 299.1 560.6 270.7 598.4 77.8 773.6 614.8 590.2 952.7 498.9 992.0 150.7 1384.0 960.5 364.3 853.1 534.5 937.9 511.1 615.8 636.6 1175.7 768.4 429.0 665.7 640.8 656.8 449.5 258.3 409.1 441.0 651.1 634.0 234.4 75.9 531.1 1602.0 214.3 511.1 423.1 978.5 694.1 631.3 494.3 316.9 655.1 158.9 564.6 227.6 278.6 749.2 763.4 734.4 337.0 342.0 268.5 413.4 2960.6 1668.4 224.8 621.0 1361.6 490.3 492.2 322.8 1.8 285.4 218.3 1752.6 312.5 430.5 167.3 442.2 199.9 135.6 517.8 43.7 117.1 0.3 976.4 188.2 359.8 1222.3 619.9 201.1 302.1 757.9 476.6 204.0 198.7 484.9 696.4 257.2 160.7 239.1 324.4 304.7 274.2 324.7 135.5 183.3 529.1 223.3 288.8 319.2 198.4 514.4 383.8 214.3 171.0 337.8 641.3 249.0 181.6 471.2 216.6 356.9 88.1 529.1 361.3 111.0 435.0 0.9 3.3 22.9 21.1 5.8 34.4 148.9 14.9 33.0 2.6 137.2 9.2 16.9 1.0 14.7 7.3 7.7 12.0 10.7 560.6 598.4 614.8 590.2 511.1 615.8 665.7 640.8 651.1 694.1 655.1 734.4 1003.1 243.6 270.0 95.0 88.2 179.8 391.8 89.7 26.2 82.7 325.6 452.0 277.4 167.3 102.3 207.8 27.1 21.8 267.1 20.0 35.2 105.7 15.9 365.4 1050.9 344.5 71.9 30.7 19.0 55.1 31.7 560.4 21.4 462.7 81.7 204.0 293.4 603.9 251.5 148.0 32.4 48.2 50.8 232.7 179.7 50.2 389.2 277.6 151.2 60.0 23.0 809.2 45.3 145.8 93.6 61.3 14.7 251.3 50.7 147.6 5.0 29.9 85.8 76.1 118.3 356.9 423.6 15.6 19.4 30.6 164.9 20.1 136.8 379.0 41.5 298.1 CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 121.3;Kupffer cells: 107.8;Langerhans cells: 148.3;Macrophages: 151.8;Microglial cells: 78.7;monocytes: 489.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 79.9;intermediate monocyte: 79.0;memory B-cell: 41.0;myeloid DC: 78.8;naive B-cell: 28.5;non-classical monocyte: 85.2" "Group enriched" "Detected in many" 18 "B-cells: 41.0;dendritic cells: 78.8;monocytes: 85.2" "Cell line enriched" "Detected in some" 7 "HDLM-2: 296.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 160000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "Centriolar satellite" "CAB004319: AB_627200, HPA026802: " "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (3.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (7.72e-3)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (9.72e-2)" "unprognostic (1.70e-2)" "unprognostic (9.78e-2)" "unprognostic (8.67e-2)" 7.8 5.3 3.5 34.5 3.4 10.3 4.4 4.0 3.6 3.5 4.8 6.3 3.7 2.4 1.0 4.0 2.1 14.3 2.7 3.2 6.1 1.9 11.2 18.6 28.8 7.2 5.5 2.1 2.6 2.9 1.1 15.0 7.0 2.4 7.7 0.9 2.3 2.5 0.8 2.0 6.8 7.4 5.3 23.4 5.2 3.1 5.0 10.6 1.3 0.8 22.0 14.9 1.0 10.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 296.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.2 0.0 32.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.4 0.0 0.1 0.0 0.1 15.1 0.6 35.1 0.0 0.9 0.0 0.1 79.9 0.8 0.0 79.0 0.0 41.0 0.2 0.3 78.8 28.5 0.2 0.1 0.9 3.7 85.2 8.3 1.6 33.4 3.5 3.4 4.0 3.6 3.2 6.1 7.2 5.5 7.0 5.3 5.0 10.2 0.9 0.0 7.7 0.3 36.5 3.6 0.1 1.3 0.0 0.0 0.4 1.3 0.3 1.5 3.2 1.8 0.0 1.8 3.3 0.0 0.0 0.2 3.7 0.1 0.0 2.6 0.0 1.3 0.2 3.5 0.8 0.8 0.5 0.0 2.5 0.1 1.8 0.8 121.3 0.0 0.3 0.0 0.0 107.8 148.3 2.7 0.0 151.8 7.2 78.7 489.4 0.0 0.0 0.5 0.1 0.3 0.0 0.0 20.6 0.3 0.0 0.1 0.1 0.4 0.0 0.3 0.7 0.2 0.3 0.2 4.0 1.9 2.1 0.1 0.0 0.3 CD8A CD8 ENSG00000153563 "CD8a molecule" P01732 2 86784610-86808396 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "lymphoid tissue: 369.0" "Group enriched" "Detected in many" 4 "dendritic cells: 111.7;T-cells: 242.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "MAIT T-cell: 234.4;memory CD8 T-cell: 523.0;naive CD8 T-cell: 476.8" "Lineage enriched" "Detected in many" 19 "T-cells: 523.0" "Cell line enhanced" "Detected in some" "JURKAT: 4.0;MOLT-4: 15.2;RPMI-8226: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000012, HPA037756, CAB075722" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 490000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB000012: AB_2075537, CAB075722: AB_2665709, HPA037756: AB_2675648" "unprognostic (1.29e-3)" "prognostic favorable (4.54e-4)" "unprognostic (9.26e-3)" "prognostic favorable (6.15e-6)" "unprognostic (7.28e-2)" "unprognostic (2.79e-3)" "unprognostic (1.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.56e-2)" 5.3 4.6 2.1 21.2 2.8 22.5 4.7 1.9 3.0 3.8 1.4 4.9 11.8 3.0 3.6 4.4 4.0 9.8 2.3 2.1 2.1 1.8 7.4 10.5 45.0 2.8 2.1 2.5 2.6 1.1 1.5 0.6 2.5 3.4 5.9 0.2 8.3 1.9 0.8 1.3 20.7 2.4 2.2 117.1 16.4 1.0 2.3 369.0 4.4 0.4 21.4 9.1 4.0 2.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.0 0.0 0.2 0.0 0.6 15.2 0.9 0.5 0.1 0.2 0.1 0.7 3.3 0.0 0.3 0.7 1.9 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.1 0.0 0.1 0.2 0.7 0.0 0.0 0.0 1.4 0.8 0.3 30.0 0.3 234.4 0.6 2.3 523.0 0.4 0.6 2.2 476.8 4.3 27.9 0.9 1.2 0.8 152.4 2.1 2.8 1.9 3.0 2.1 2.1 2.8 2.1 2.5 2.2 2.3 2.1 2.2 0.0 4.6 0.0 5.7 2.0 0.2 0.0 0.0 0.3 1.5 1.5 3.4 1.5 0.6 0.0 0.0 0.0 111.7 0.2 0.0 0.2 0.3 0.5 0.3 1.3 0.0 7.8 4.2 0.0 0.0 2.6 8.2 0.4 2.5 0.0 6.4 2.3 0.1 0.0 3.1 0.3 0.0 1.9 11.5 0.2 0.0 6.6 0.0 1.0 5.9 0.1 38.1 0.0 0.2 0.0 0.0 0.0 30.8 0.2 0.0 0.4 1.5 0.4 0.0 1.1 1.4 0.4 0.4 1.1 1.8 0.1 242.4 0.0 0.6 0.1 CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 459.6" "Group enriched" "Detected in many" 8 "dendritic cells: 53.2;T-cells: 162.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 601.8;naive CD8 T-cell: 1053.9" "Lineage enriched" "Detected in all" 25 "T-cells: 1053.9" "Cell line enriched" "Detected in some" 60 "RPMI-8226: 1113.4" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB004353: AB_627211, HPA029164: AB_2672936" "unprognostic (1.83e-3)" "unprognostic (1.98e-3)" "unprognostic (2.22e-2)" "prognostic favorable (7.88e-7)" "unprognostic (6.23e-2)" "unprognostic (7.05e-3)" "unprognostic (1.11e-2)" "unprognostic (2.59e-2)" "unprognostic (5.50e-3)" "unprognostic (5.91e-2)" "unprognostic (9.25e-2)" "unprognostic (4.60e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (7.84e-2)" "unprognostic (3.00e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-2)" 1.9 1.9 0.4 10.6 0.3 8.3 2.9 1.1 0.6 33.4 0.1 2.1 5.0 1.2 1.1 1.6 1.5 4.3 1.0 0.1 1.2 1.0 1.6 4.2 25.9 5.0 2.1 0.9 0.9 4.6 8.8 0.3 4.8 1.7 3.0 0.0 2.4 1.0 0.6 1.4 15.1 1.1 0.7 15.6 5.1 0.4 2.4 459.6 2.0 0.4 15.1 3.4 1.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.1 0.2 0.0 1113.4 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 6.6 0.0 0.0 0.0 42.0 1.0 0.8 15.7 1.1 79.3 0.7 1.9 601.8 0.6 1.2 4.6 1053.9 6.1 1.1 1.7 1.0 2.2 427.6 0.4 0.3 1.1 0.6 0.1 1.2 5.0 2.1 4.8 0.7 2.4 0.5 1.3 6.4 5.5 0.0 4.4 4.0 2.2 0.0 0.6 0.0 2.2 2.8 1.0 1.5 0.0 0.0 0.0 0.1 53.2 0.1 0.0 0.1 0.5 0.2 0.5 0.7 0.0 1.7 0.4 0.0 0.0 2.0 7.1 0.2 0.0 0.0 0.7 0.5 0.1 0.0 0.5 4.6 0.0 4.0 4.3 0.5 0.0 4.1 5.4 5.6 7.5 0.0 10.3 0.0 0.1 0.0 0.1 0.0 10.8 0.7 12.4 0.2 0.0 0.0 0.0 2.0 1.2 0.2 0.1 0.5 2.8 0.0 162.9 0.0 7.5 0.3 CD9 "BA2, MIC3, MRP-1, P24, TSPAN29" ENSG00000010278 "CD9 molecule" P21926 12 6199715-6238271 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2822.0;Ionocytes: 4461.6;Urothelial cells: 2594.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "basophil: 1957.3;eosinophil: 1156.4" "Lineage enriched" "Detected in all" 32 "granulocytes: 1957.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 1521.6;RT4: 1126.8;TIME: 2266.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002490 Supported Supported "Plasma membrane" "Intracellular and membrane" NA NA 1200000 "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB002490: AB_563643" "unprognostic (1.38e-1)" "unprognostic (6.36e-3)" "unprognostic (8.27e-3)" "unprognostic (6.98e-3)" "unprognostic (3.89e-1)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (2.90e-1)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.30e-1)" "prognostic favorable (6.49e-5)" "unprognostic (6.10e-2)" "unprognostic (1.77e-1)" "prognostic favorable (8.93e-5)" "unprognostic (9.26e-2)" 204.4 287.8 116.9 96.5 162.9 17.3 298.9 139.8 193.3 399.5 157.3 496.9 127.2 242.4 270.9 1000.2 242.3 102.4 267.5 124.3 132.3 294.2 79.4 403.0 37.4 165.8 141.0 69.0 93.4 881.8 98.1 85.4 160.2 488.5 466.2 32.6 614.5 456.4 74.4 455.3 211.2 197.0 139.2 69.5 178.2 26.4 146.5 66.1 338.0 116.6 289.4 373.1 566.4 207.1 417.6 173.7 3.5 108.7 167.7 170.8 150.1 241.1 477.8 80.8 121.9 128.5 1521.6 1.4 59.2 51.4 239.0 885.6 92.7 475.5 62.7 21.5 63.1 2.0 117.1 26.6 71.3 1.1 497.0 0.6 347.0 147.3 126.0 225.3 976.3 28.9 19.3 1.7 51.5 578.6 1.8 45.4 136.0 504.3 175.7 4.1 290.1 529.7 802.1 1126.8 0.5 34.0 240.9 195.8 215.8 789.0 91.1 42.1 2266.0 8.6 214.6 8.8 29.5 1.7 1.3 63.2 137.2 1.0 221.7 1957.3 61.1 1156.4 1.3 23.6 2.2 5.5 1.4 1.6 10.2 20.5 4.2 11.5 30.9 2.6 0.6 3.7 0.4 71.7 116.9 162.9 139.8 193.3 124.3 132.3 165.8 141.0 160.2 139.2 146.5 207.1 250.0 794.9 403.1 35.6 27.8 1037.8 1864.4 2822.0 804.1 4.9 433.5 379.5 20.9 84.4 1403.7 1075.9 0.0 21.5 8.7 929.9 137.0 599.1 3.0 457.8 66.8 496.5 172.9 10.5 0.4 178.2 271.0 356.9 60.6 722.6 653.4 42.3 522.6 43.1 618.0 0.0 0.6 744.8 4461.6 35.2 685.3 13.1 32.0 253.4 940.9 11.2 151.7 375.1 2.1 56.3 169.5 352.9 896.4 70.7 59.3 1576.4 330.0 21.7 1409.8 14.7 664.0 322.6 397.5 7.3 74.1 1214.3 1279.8 54.0 77.8 838.5 761.1 2594.9 CD99L2 "CD99B, MIC2L1" ENSG00000102181 "CD99 molecule like 2" Q8TCZ2 X 150766336-150898816 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 179.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 49.1;Horizontal cells: 52.2;Inhibitory neurons: 57.2;Oligodendrocytes: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038782, HPA038783, HPA061400" Enhanced Supported "Plasma membrane" NA NA 1200000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA038782: AB_10795139, HPA038783: AB_10794734, HPA061400: AB_2732660" "unprognostic (2.10e-2)" "unprognostic (2.62e-3)" "unprognostic (3.12e-3)" "unprognostic (6.03e-3)" "unprognostic (1.22e-1)" "unprognostic (2.66e-1)" "unprognostic (5.56e-2)" "prognostic favorable (4.96e-4)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.74e-5)" "unprognostic (5.50e-2)" "unprognostic (5.13e-2)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (9.23e-2)" "prognostic unfavorable (8.74e-4)" 46.1 28.1 68.5 14.8 69.5 7.3 29.7 71.0 99.6 33.4 26.8 40.1 10.0 39.9 24.5 14.5 30.5 19.2 61.6 69.9 80.4 24.9 47.3 25.2 13.2 104.7 77.9 38.9 18.7 14.6 23.8 21.5 107.2 25.8 10.6 43.4 14.8 32.6 179.1 13.4 19.2 32.4 71.5 26.9 21.8 11.2 91.6 14.5 16.8 99.2 10.7 29.4 21.0 80.2 8.1 79.8 29.5 36.9 153.3 95.2 8.7 65.2 76.1 32.3 46.3 5.5 10.2 29.3 154.0 114.6 24.2 13.0 40.4 44.4 26.6 68.5 31.9 12.7 17.8 8.2 41.2 21.4 23.3 90.3 14.5 24.0 45.4 50.3 38.6 22.4 8.9 74.9 41.1 17.3 18.9 31.1 12.4 6.9 42.7 18.8 24.2 40.5 31.7 5.4 38.9 19.9 25.8 21.9 29.6 21.6 6.2 36.6 45.8 47.5 14.4 62.2 48.0 62.6 112.3 28.3 59.6 42.3 36.4 7.3 8.6 5.9 6.2 7.6 5.4 4.5 5.8 6.3 8.1 4.8 5.5 6.0 2.1 7.2 12.5 5.8 4.4 7.0 68.5 69.5 71.0 99.6 69.9 80.4 104.7 77.9 107.2 71.5 91.6 80.2 14.1 16.0 7.8 21.5 8.2 3.1 2.3 3.6 4.6 26.8 3.7 3.2 42.8 11.5 6.4 12.9 18.8 10.1 7.4 2.0 5.9 4.4 0.3 5.6 10.1 13.8 8.4 6.5 49.1 5.3 3.9 15.9 7.1 3.6 7.6 12.6 17.2 26.6 10.2 52.2 57.2 2.9 8.2 16.4 6.8 2.8 20.8 8.6 10.6 23.4 8.1 18.2 2.1 21.6 60.7 3.6 3.1 30.1 12.5 3.4 5.3 11.3 5.0 18.7 0.0 15.9 12.0 2.8 4.9 3.3 1.3 13.5 6.4 11.8 3.3 1.3 CDAN1 "CDA-I, CDAI" ENSG00000140326 "Codanin 1" Q8IWY9 15 42723544-42737128 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 19.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039404, HPA040787" Supported Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane" "HPA039404: AB_10673530, HPA040787: AB_2677137" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (5.79e-3)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" "unprognostic (7.71e-2)" "prognostic unfavorable (1.07e-4)" "unprognostic (7.17e-2)" "unprognostic (9.82e-2)" "unprognostic (1.24e-1)" "unprognostic (2.95e-2)" "unprognostic (1.26e-1)" "unprognostic (4.35e-3)" "unprognostic (2.05e-1)" "unprognostic (1.16e-1)" "unprognostic (9.20e-3)" "unprognostic (2.04e-1)" 4.0 5.0 2.1 3.6 2.2 8.1 4.3 4.3 3.1 7.7 3.2 4.5 2.8 5.9 4.4 4.1 6.1 2.5 2.9 2.1 0.9 3.2 4.0 3.5 4.2 3.0 1.5 11.3 4.8 3.5 5.1 3.2 2.7 6.9 2.5 2.6 5.4 3.5 4.2 4.9 4.2 2.8 0.7 4.6 4.5 6.3 1.4 5.2 5.1 2.8 3.4 5.8 5.6 2.6 8.1 5.4 7.2 10.4 6.3 5.4 8.6 10.4 4.3 9.9 7.2 13.6 4.2 3.9 11.2 5.8 9.7 15.5 7.7 4.7 2.9 9.9 7.2 14.5 10.3 5.3 4.7 10.8 13.2 7.4 5.2 6.3 4.5 6.1 7.6 13.0 18.9 5.7 8.2 4.5 8.4 14.2 3.6 7.7 8.5 11.9 9.0 3.4 3.1 7.9 5.9 6.8 8.2 11.3 1.7 4.6 8.6 15.9 5.6 10.4 9.2 8.6 12.1 11.2 12.7 8.7 5.4 15.8 8.6 1.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 2.1 2.2 4.3 3.1 2.1 0.9 3.0 1.5 2.7 0.7 1.4 2.6 2.0 0.0 3.7 4.6 2.4 1.9 2.0 1.5 1.8 3.3 3.2 1.8 2.2 2.8 1.5 7.3 4.2 3.0 2.6 1.9 0.0 1.5 0.4 2.0 2.8 2.3 4.8 1.7 7.6 1.8 1.6 2.9 3.6 2.0 1.3 9.0 3.9 3.6 2.1 1.7 6.3 1.6 4.1 2.5 0.9 1.2 4.4 1.6 0.0 4.7 1.5 4.5 2.1 5.5 3.8 1.6 0.5 4.9 2.5 2.3 2.2 1.3 1.9 4.7 19.7 3.4 2.4 5.4 2.1 2.8 1.3 2.2 2.5 4.6 2.6 1.7 CDC42EP1 "Borg5, CEP1, MSE55" ENSG00000128283 "CDC42 effector protein 1" Q00587 22 37560480-37569405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 245.6;Exocrine glandular cells: 226.0;Pancreatic endocrine cells: 266.2;Urothelial cells: 161.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 7.3;intermediate monocyte: 1.9;myeloid DC: 2.4" "Group enriched" "Detected in many" 10 "dendritic cells: 2.4;monocytes: 7.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006379, HPA076536" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA006379: AB_1078486, HPA076536: " "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (2.44e-1)" "unprognostic (3.79e-3)" "unprognostic (5.82e-2)" "unprognostic (4.06e-2)" "unprognostic (4.38e-2)" "unprognostic (5.57e-2)" "unprognostic (9.45e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-2)" "unprognostic (3.85e-2)" "unprognostic (3.81e-2)" "unprognostic (1.09e-3)" 76.3 91.2 55.7 16.7 107.5 1.6 58.0 89.9 73.3 68.2 17.6 43.7 31.1 70.7 4.1 93.1 61.0 40.8 53.8 55.9 67.3 50.2 133.1 65.2 11.3 102.8 104.5 60.9 161.6 16.5 18.8 31.8 97.4 41.5 14.4 2.6 102.7 23.9 13.1 71.2 32.7 19.6 70.2 26.2 155.9 23.6 87.5 2.7 33.7 11.1 10.4 38.4 69.6 151.5 125.2 35.4 15.1 67.9 23.7 40.2 73.3 69.9 41.0 78.9 54.3 87.8 15.9 0.2 24.2 81.4 25.4 95.0 17.8 35.1 26.0 15.5 60.7 0.5 33.9 53.6 167.7 0.3 0.6 74.9 52.1 65.0 61.5 63.1 59.2 0.1 78.9 0.7 33.0 42.6 0.3 0.5 13.6 96.5 79.6 0.4 27.5 2.4 27.9 1.9 0.4 2.6 51.2 112.3 112.4 20.6 50.3 11.0 91.6 163.9 98.2 80.0 98.6 0.2 0.8 0.3 65.3 0.7 135.6 0.4 7.3 0.0 0.1 1.9 0.1 0.0 0.1 0.1 2.4 0.3 0.0 0.2 0.2 0.4 0.1 0.3 0.0 3.4 55.7 107.5 89.9 73.3 55.9 67.3 102.8 104.5 97.4 70.2 87.5 151.5 62.4 6.4 19.5 2.3 1.8 46.9 87.2 51.4 21.1 0.1 59.2 31.8 3.5 134.4 41.1 12.9 0.0 98.2 2.0 41.6 1.9 245.6 3.7 4.3 20.0 54.7 11.5 0.0 0.1 226.0 110.3 32.1 133.0 9.0 2.5 1.7 69.7 35.6 13.2 1.7 0.2 66.6 30.5 5.9 29.3 1.7 39.4 5.3 21.4 4.7 8.9 12.8 0.0 2.0 42.7 266.2 45.8 35.3 0.6 122.4 17.5 11.4 14.7 0.3 39.5 22.8 49.5 2.0 0.6 55.9 52.0 112.2 2.2 7.0 61.1 161.3 CDC42EP3 "BORG2, CEP3, UB1" ENSG00000163171 "CDC42 effector protein 3" Q9UKI2 2 37641882-37738468 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 233.5;Langerhans cells: 259.6;Melanocytes: 200.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 24.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 607.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034986, HPA061792" Approved Supported "Plasma membrane,Actin filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA034986: AB_10602207, HPA061792: AB_2732670" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-2)" "unprognostic (4.11e-3)" "unprognostic (2.38e-2)" "unprognostic (2.72e-3)" "unprognostic (1.41e-1)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "unprognostic (3.81e-1)" "unprognostic (3.14e-3)" "unprognostic (7.30e-3)" "unprognostic (1.97e-1)" "unprognostic (2.97e-1)" "unprognostic (4.53e-2)" 55.2 10.3 4.4 21.9 5.4 86.5 38.8 0.4 24.8 50.5 22.2 42.4 6.1 92.7 10.7 21.1 24.3 21.2 59.6 7.2 6.9 24.4 9.0 29.3 25.5 2.8 3.9 23.8 27.2 8.3 6.8 26.3 5.9 93.4 20.6 15.4 14.6 107.0 57.7 15.1 17.3 96.4 2.2 26.8 14.4 41.9 5.5 36.2 15.9 22.0 23.4 45.4 20.3 3.3 100.2 38.0 21.6 1.2 80.6 42.2 33.8 84.2 221.1 127.5 92.2 69.8 39.3 17.6 66.5 198.9 39.2 47.1 27.1 99.6 129.4 68.2 9.5 31.6 37.5 0.0 156.1 7.1 1.8 129.6 91.7 110.1 243.2 206.6 75.6 7.0 5.0 13.8 607.0 0.8 3.4 59.3 44.1 1.2 23.5 2.8 163.8 9.3 93.1 47.4 23.7 69.9 41.6 29.7 50.2 37.7 9.9 58.8 57.5 152.3 40.0 40.2 86.9 27.0 37.9 5.9 63.1 48.4 215.4 54.6 88.2 6.9 69.4 56.7 74.6 24.9 44.5 60.2 30.9 11.0 14.3 37.3 189.4 38.3 119.5 0.9 35.8 61.5 4.4 5.4 0.4 24.8 7.2 6.9 2.8 3.9 5.9 2.2 5.5 3.3 233.5 6.4 50.4 1.6 50.3 37.1 137.3 81.4 5.7 12.3 31.9 40.1 97.5 12.8 28.9 31.3 35.5 30.8 63.8 7.8 9.8 20.8 51.7 49.6 24.4 113.9 41.2 14.5 15.6 15.9 68.2 29.7 14.3 33.6 129.6 9.2 83.2 1.5 12.2 101.0 34.9 59.6 32.6 44.1 259.6 158.0 15.2 86.0 200.9 9.4 78.6 27.5 106.1 4.0 0.5 24.9 3.0 126.7 43.4 32.7 1.1 5.0 73.3 13.2 0.0 29.2 29.4 67.2 13.6 3.1 13.5 12.0 97.7 1.4 6.0 38.5 CDC42EP4 "BORG4, CEP4, KAIA1777, MGC17125, MGC3740" ENSG00000179604 "CDC42 effector protein 4" Q9H3Q1 17 73283624-73312005 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Horizontal cells: 753.7;Muller glia cells: 570.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023335, HPA024797" Approved Supported Supported "Plasma membrane,Actin filaments,Microtubules" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "Actin filaments, Microtubules" "Plasma membrane" "HPA023335: AB_10603783, HPA024797: AB_10600696" "unprognostic (8.76e-2)" "unprognostic (4.38e-3)" "unprognostic (1.49e-2)" "unprognostic (5.43e-3)" "unprognostic (6.29e-2)" "unprognostic (9.01e-3)" "unprognostic (2.44e-3)" "unprognostic (1.08e-1)" "unprognostic (8.00e-2)" "unprognostic (2.41e-1)" "unprognostic (4.16e-2)" "unprognostic (6.73e-2)" "unprognostic (3.97e-1)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "unprognostic (1.10e-1)" "unprognostic (1.94e-1)" 94.5 54.9 84.9 15.3 84.7 14.9 74.5 90.6 76.3 47.4 75.0 55.6 35.7 52.7 60.1 33.3 69.4 19.1 50.5 82.2 103.1 28.6 32.2 38.6 16.1 141.9 104.5 70.7 77.5 20.5 45.0 22.9 83.7 38.7 17.4 98.1 41.5 43.1 28.8 40.6 36.0 25.5 103.5 24.1 42.4 20.5 105.9 20.2 45.4 18.8 27.6 33.8 39.5 109.5 30.1 70.1 24.7 20.9 48.8 40.5 65.0 26.2 32.6 24.3 17.9 14.8 42.1 0.1 22.9 31.6 27.6 20.6 17.2 18.0 14.6 1.4 17.0 6.7 35.2 34.7 24.3 1.1 7.3 51.4 14.9 21.2 10.5 19.2 27.9 0.6 18.9 1.4 14.9 23.2 1.2 8.6 13.5 87.8 48.4 0.8 11.0 3.1 28.8 34.3 16.4 24.8 19.7 53.1 18.4 19.0 64.3 9.8 28.7 22.7 47.6 18.1 18.9 1.4 1.2 0.2 37.3 4.7 60.7 3.3 3.2 5.9 0.1 8.5 0.2 0.1 0.0 0.0 4.3 0.0 0.2 0.0 5.4 0.3 20.1 0.1 0.0 2.1 84.9 84.7 90.6 76.3 82.2 103.1 141.9 104.5 83.7 103.5 105.9 109.5 117.1 12.8 15.6 54.9 2.8 48.7 58.5 54.9 97.9 11.5 45.8 37.1 10.8 31.5 29.1 12.9 6.2 32.1 2.5 47.3 11.7 29.4 0.6 29.7 47.6 43.8 31.2 9.1 1.0 43.6 35.0 46.1 31.1 41.2 13.3 19.6 42.8 27.7 6.1 753.7 1.3 41.3 14.2 5.5 30.1 2.7 18.3 9.1 30.2 6.5 11.1 570.4 0.0 2.5 2.5 30.4 33.5 15.4 2.5 42.6 53.1 8.0 18.0 26.2 131.5 98.0 69.9 1.1 2.0 83.2 44.9 84.3 6.0 13.6 30.2 124.1 CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737292-68835537 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 197.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 451.6;Glandular and luminal cells: 321.0;Pancreatic endocrine cells: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 13 "myeloid DC: 1.7;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 19 "dendritic cells: 4.7" "Cell line enhanced" "Detected in many" "BEWO: 683.3;CACO-2: 241.9;CAPAN-2: 328.1;HaCaT: 318.7;hTCEpi: 217.2;MCF7: 199.6;OE19: 207.2;RT4: 237.7;T-47d: 209.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA 78000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.12e-3)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.04e-3)" "unprognostic (1.63e-1)" "unprognostic (5.47e-2)" "unprognostic (2.85e-1)" "unprognostic (1.19e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.06e-4)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (2.51e-1)" "unprognostic (5.92e-2)" 1.0 0.2 1.5 16.1 2.0 6.5 64.2 0.6 1.9 30.0 19.3 127.5 133.9 9.6 39.5 76.9 51.5 45.7 0.3 1.5 1.3 39.8 97.2 36.8 5.6 2.0 1.3 1.3 84.0 197.8 8.0 60.9 1.3 91.7 131.0 0.1 71.9 41.7 0.3 107.7 127.9 5.1 2.1 10.3 104.2 0.4 2.3 20.1 162.7 0.1 29.0 58.2 38.1 2.7 147.0 14.8 0.0 0.5 0.0 0.0 683.3 0.0 0.0 0.0 0.0 241.9 328.1 0.0 3.1 0.0 0.0 318.7 0.0 156.3 0.0 28.6 3.5 0.1 0.7 48.0 0.0 0.0 0.6 0.0 217.2 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 199.6 0.2 1.0 5.5 207.2 0.8 0.1 0.1 2.1 53.9 237.7 8.5 0.8 1.4 0.2 58.9 91.8 209.2 0.4 0.0 0.4 0.9 0.7 0.6 0.1 0.3 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.2 0.0 4.7 0.0 0.1 1.5 2.0 0.6 1.9 1.5 1.3 2.0 1.3 1.3 2.1 2.3 2.7 0.6 131.4 69.8 0.7 1.4 94.1 130.3 73.8 45.5 0.0 137.6 83.6 0.9 128.7 95.3 163.7 0.0 117.6 2.5 451.6 1.9 129.1 0.1 159.3 29.2 4.4 86.7 9.0 0.7 113.5 29.6 3.4 132.0 321.0 1.3 2.8 0.4 63.4 11.7 0.0 1.4 208.3 75.3 1.2 13.4 0.0 0.3 3.2 53.4 1.0 3.3 0.0 0.0 0.5 32.1 264.6 204.6 0.4 2.2 195.5 159.5 4.5 118.2 0.0 0.0 0.0 7.1 0.1 0.1 100.6 131.6 50.5 2.7 0.0 154.8 251.5 CDH13 CDHH ENSG00000140945 "Cadherin 13" P55290 16 82626965-83800640 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 57.1;skeletal muscle: 68.6;tongue: 57.7" "Group enriched" "Detected in many" 4 "Excitatory neurons: 328.8;Inhibitory neurons: 867.0;Oligodendrocyte precursor cells: 335.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.3" "Group enriched" "Detected in many" 6 "granulocytes: 2.2;monocytes: 4.3" "Cell line enhanced" "Detected in many" "LHCN-M2: 222.2;U-138 MG: 279.2;U-87 MG: 244.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001380, CAB025863" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 240000000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB025863: , HPA001380: AB_1078371" "unprognostic (2.50e-2)" "unprognostic (2.75e-2)" "unprognostic (5.61e-2)" "unprognostic (4.06e-1)" "unprognostic (4.88e-2)" "unprognostic (3.30e-3)" "unprognostic (3.01e-1)" "unprognostic (5.76e-2)" "unprognostic (3.49e-2)" "unprognostic (3.34e-1)" "unprognostic (2.21e-1)" "unprognostic (3.26e-1)" "prognostic unfavorable (1.73e-6)" "unprognostic (5.16e-3)" "unprognostic (2.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" 20.3 2.8 18.7 3.8 21.5 0.6 10.0 0.0 14.3 42.5 0.0 5.0 1.5 47.2 3.3 9.5 7.6 5.0 57.1 10.5 3.3 5.0 1.8 16.1 1.4 1.5 6.5 3.1 0.6 2.4 0.5 6.0 0.6 3.5 6.2 1.5 4.9 7.2 68.6 21.1 2.3 29.9 6.3 2.1 1.7 1.8 22.9 1.8 5.8 57.7 1.9 7.1 19.4 3.2 10.2 0.0 3.6 0.5 63.2 60.6 0.1 47.1 51.9 53.6 23.1 0.1 0.4 0.1 8.5 138.5 26.0 89.1 1.0 70.7 79.8 0.0 0.2 0.1 31.4 0.1 36.4 0.0 0.4 7.9 59.9 107.8 130.4 83.9 26.7 0.0 0.2 0.5 222.2 0.5 0.1 0.2 10.6 0.0 19.4 0.0 57.7 0.0 46.2 0.4 0.1 0.1 84.4 0.3 0.1 103.5 0.8 0.1 43.1 279.2 22.7 1.6 43.0 0.2 0.1 0.2 244.0 0.2 70.1 2.2 0.5 1.4 0.0 2.1 0.0 0.5 0.0 0.0 0.5 0.5 0.0 0.0 1.1 0.0 4.3 0.3 0.0 0.2 18.7 21.5 0.0 14.3 10.5 3.3 1.5 6.5 0.6 6.3 22.9 3.2 125.4 0.0 0.5 11.1 0.3 70.7 28.7 32.3 25.0 3.0 1.0 5.8 86.9 0.0 2.6 3.7 0.0 0.1 0.9 2.1 7.9 0.4 44.5 1.0 27.1 49.2 1.8 0.0 328.8 0.0 0.2 9.7 0.0 0.7 0.0 0.0 29.6 0.3 0.6 5.0 867.0 1.6 0.0 1.9 13.3 43.3 0.3 1.4 8.8 17.8 0.0 0.4 0.0 335.8 65.0 0.1 1.4 0.0 0.0 36.7 0.0 1.3 0.8 0.4 0.0 51.0 22.7 2.9 0.6 3.3 18.8 0.1 1.2 0.7 0.1 6.4 CDH2 "CD325, CDHN, NCAD" ENSG00000170558 "Cadherin 2" P19022 18 27932879-28177946 "CD markers, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 196.0" "Cell type enhanced" "Detected in many" "Astrocytes: 217.7;Cardiomyocytes: 368.8;Excitatory neurons: 311.2;Granulosa cells: 312.5;Inhibitory neurons: 198.2;Muller glia cells: 157.9;Oligodendrocyte precursor cells: 267.9" "Cancer enhanced" "Detected in all" "glioma: 39.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.7;neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.7" "Cell line enhanced" "Detected in many" "AF22: 278.2;BJ: 230.7;fHDF/TERT166: 459.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000141, CAB018580, HPA058574, CAB078686" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 160000000 "Cluster 10: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB000141: , CAB018580: AB_626778, CAB078686: AB_2665849, HPA058574: AB_2683760" "unprognostic (9.42e-2)" "unprognostic (2.69e-3)" "unprognostic (9.07e-3)" "unprognostic (5.45e-2)" "unprognostic (1.14e-1)" "unprognostic (9.30e-2)" "unprognostic (3.97e-2)" "unprognostic (2.53e-3)" "unprognostic (6.70e-3)" "unprognostic (1.00e-2)" "unprognostic (7.53e-2)" "unprognostic (3.51e-2)" "unprognostic (3.02e-2)" "unprognostic (1.93e-3)" "unprognostic (6.69e-2)" "unprognostic (1.33e-1)" "unprognostic (2.59e-3)" 0.6 66.5 27.4 2.6 29.0 0.2 0.3 20.6 31.6 6.6 7.9 4.8 0.8 6.2 1.1 0.4 10.5 3.1 196.0 30.0 31.6 18.1 57.2 1.0 1.9 21.7 26.3 6.7 0.9 29.8 8.1 0.4 20.1 2.4 1.1 60.3 0.4 10.8 0.4 0.3 1.4 6.8 24.1 13.5 5.9 44.4 33.3 3.8 6.2 2.2 1.6 1.1 2.7 22.7 0.3 25.8 278.2 0.3 48.1 7.8 0.2 230.7 72.0 94.9 80.8 0.1 0.4 0.0 128.3 459.1 46.0 36.7 50.0 0.2 130.4 0.4 35.8 0.0 66.8 86.7 48.0 0.0 0.1 4.6 0.4 198.6 37.4 212.9 84.0 15.4 0.0 0.1 77.8 0.0 59.4 0.1 43.8 0.1 30.5 0.2 37.1 45.6 0.1 9.9 83.4 144.4 0.1 0.2 26.8 116.8 0.3 0.5 11.6 206.6 63.6 2.9 181.6 0.2 0.3 0.3 40.6 0.2 163.0 1.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 27.4 29.0 20.6 31.6 30.0 31.6 21.7 26.3 20.1 24.1 33.3 22.7 0.8 0.0 0.6 217.7 1.2 0.3 0.0 3.4 0.0 38.7 1.6 0.4 368.8 67.2 1.2 11.0 150.1 0.1 0.0 0.0 0.0 12.9 53.2 1.4 15.2 9.8 0.0 6.1 311.2 0.4 0.0 16.7 0.0 2.6 0.0 312.5 12.5 125.3 0.3 3.3 198.2 0.0 2.0 2.2 0.4 17.7 2.1 1.2 3.6 106.8 0.1 157.9 0.0 267.9 138.6 19.2 0.0 12.8 0.0 0.1 0.0 47.5 1.7 99.9 6.6 0.4 45.8 4.8 24.1 0.0 0.0 0.3 0.6 1.6 0.0 0.1 CDH26 VR20 ENSG00000124215 "Cadherin 26" Q8IXH8 20 59958423-60034011 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 8.0" "Cell type enhanced" "Detected in many" "Astrocytes: 17.9;Club cells: 18.7;Oligodendrocytes: 14.9;Respiratory ciliated cells: 39.6;Syncytiotrophoblasts: 14.9" "Group enriched" "Detected in some" 6 "cervical cancer: 1.5;head and neck cancer: 0.9;lung cancer: 2.3;prostate cancer: 3.6;urothelial cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RT4: 36.4" "Low region specificity" "Detected in some" "HPA015722, HPA047578" Uncertain Supported "Plasma membrane,Microtubules" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" Microtubules "HPA015722: AB_2077659, HPA047578: AB_2680091" "unprognostic (2.42e-1)" "prognostic favorable (7.62e-4)" "unprognostic (4.71e-4)" "unprognostic (8.17e-2)" "unprognostic (9.40e-2)" "unprognostic (9.95e-3)" "unprognostic (6.65e-2)" "prognostic favorable (3.75e-4)" "unprognostic (1.37e-1)" "unprognostic (1.69e-1)" "unprognostic (3.26e-4)" "unprognostic (8.24e-3)" "unprognostic (9.96e-7)" "unprognostic (1.85e-2)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" 0.9 0.4 1.0 0.3 1.5 1.0 0.8 1.2 2.0 2.0 0.3 0.7 0.4 0.6 0.4 3.4 2.0 0.4 0.7 0.9 1.8 0.5 0.3 2.1 0.4 1.6 1.7 0.3 0.5 0.3 1.7 0.4 1.5 8.0 0.3 0.4 2.0 0.5 1.0 0.6 0.8 0.4 0.6 0.8 1.2 0.7 1.9 0.9 0.6 0.3 3.0 2.7 1.3 2.6 0.0 0.7 0.2 0.0 0.6 0.2 0.4 0.2 0.0 0.1 0.0 0.8 0.8 0.1 0.5 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.1 7.9 0.1 0.1 0.0 0.3 0.3 0.1 1.1 0.1 0.0 0.0 0.0 0.4 0.0 0.3 0.3 0.3 0.3 0.4 0.4 0.0 0.1 0.0 0.0 0.7 0.1 36.4 0.8 0.1 0.4 0.2 0.1 0.4 0.2 0.4 0.2 0.0 0.0 1.0 0.0 0.3 0.2 0.0 0.0 1.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.5 1.2 2.0 0.9 1.8 1.6 1.7 1.5 0.6 1.9 2.6 4.3 6.4 6.1 17.9 0.1 0.1 1.2 6.6 0.0 0.5 1.6 0.5 0.7 0.0 18.7 0.0 0.0 1.7 0.0 0.2 0.0 0.0 3.2 2.1 0.4 2.1 0.0 2.5 9.3 0.0 0.0 0.3 0.0 0.4 1.3 0.0 0.7 0.1 0.6 0.0 8.4 0.0 6.1 1.3 0.4 1.7 0.0 1.4 0.0 7.5 0.6 0.2 1.0 7.1 14.9 0.0 0.0 0.0 0.4 10.9 0.2 0.1 39.6 0.0 0.0 0.5 2.4 0.9 0.2 0.2 0.0 14.9 0.2 0.1 0.2 7.4 CDH3 "CDHP, PCAD" ENSG00000062038 "Cadherin 3" P22223 16 68636189-68727468 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Sensory transduction, Vision" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.1;ovary: 32.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 60.8;Basal prostatic cells: 67.2;Basal respiratory cells: 161.4;Basal squamous epithelial cells: 71.7;Granulosa cells: 77.6;Melanocytes: 60.5;Pancreatic endocrine cells: 85.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 100.6;HaCaT: 263.9;HBEC3-KT: 126.9;hTCEpi: 94.3;hTERT-HME1: 72.7;RPTEC TERT1: 116.8" "Region enhanced" "Detected in single" "olfactory bulb: 1.7" "Low region specificity" "Detected in all" "HPA001767, CAB002487" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 510000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "Cell Junctions" "CAB002487: AB_563446, HPA001767: AB_1078376" "unprognostic (1.55e-1)" "unprognostic (2.47e-2)" "unprognostic (1.33e-1)" "unprognostic (4.38e-3)" "unprognostic (6.73e-2)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "prognostic unfavorable (8.53e-4)" "unprognostic (1.22e-1)" "unprognostic (3.45e-2)" "prognostic unfavorable (8.43e-4)" "unprognostic (4.30e-2)" "unprognostic (2.41e-5)" "unprognostic (2.11e-1)" "unprognostic (1.09e-1)" "unprognostic (1.33e-3)" "unprognostic (8.56e-2)" 3.6 0.2 1.3 3.4 1.5 0.1 8.2 1.9 1.6 9.7 47.1 0.4 0.5 10.0 8.8 26.8 12.0 1.5 0.3 3.5 0.8 6.0 0.0 2.0 2.5 1.2 1.0 32.7 0.6 1.5 4.4 4.5 0.6 13.6 0.7 0.8 12.4 4.6 0.2 25.8 0.7 4.0 1.9 10.9 1.0 1.6 1.1 18.8 1.2 0.0 11.7 3.9 11.2 1.1 100.6 0.2 0.9 0.1 0.1 0.0 8.6 0.0 0.0 0.3 0.1 61.4 36.6 0.0 0.4 0.0 0.2 263.9 2.6 126.9 0.4 0.0 1.2 0.0 0.2 0.0 0.2 0.2 0.5 0.0 94.3 0.1 72.7 0.3 0.0 0.0 0.0 0.2 0.0 48.8 0.1 0.1 5.3 0.9 8.8 0.0 0.0 0.0 116.8 44.5 0.5 0.2 0.8 0.0 50.0 45.6 29.2 0.2 0.0 0.0 0.2 0.0 0.3 0.1 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 1.6 3.5 0.8 1.2 1.0 0.6 1.9 1.1 1.1 0.2 16.0 4.6 0.7 0.0 60.8 67.2 161.4 71.7 1.2 6.8 39.2 1.4 0.0 35.9 14.7 2.1 23.4 0.5 0.5 0.0 35.7 0.5 0.9 8.2 1.3 1.2 0.0 6.0 32.1 2.1 3.7 0.0 0.9 1.3 77.6 0.0 0.0 2.8 0.0 9.1 1.5 20.3 0.0 1.9 0.2 0.6 0.7 60.5 0.0 1.0 0.4 1.0 3.0 2.2 85.7 0.1 9.4 1.2 44.5 0.0 0.1 12.6 0.5 0.0 0.6 5.9 0.4 1.0 26.5 30.7 6.3 1.2 0.1 1.5 43.1 CDH4 ENSG00000179242 "Cadherin 4" P55283 20 61252261-61940617 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.0;lymphoid tissue: 3.7;ovary: 6.3;skeletal muscle: 3.8" "Cell type enhanced" "Detected in some" "Astrocytes: 157.0;Excitatory neurons: 54.4;Inhibitory neurons: 70.0;Oligodendrocyte precursor cells: 108.0;Skeletal myocytes: 28.7" "Group enriched" "Detected in many" 6 "glioma: 6.9;renal cancer: 3.4;thyroid cancer: 2.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 10.8;hTERT-HME1: 14.1;U-2 OS: 19.4;U-251 MG: 35.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015613 Supported "Plasma membrane" NA NA 19000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 65: Brain - Ion transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA015613: AB_2732414" "unprognostic (1.64e-1)" "unprognostic (1.19e-2)" "unprognostic (3.39e-4)" "unprognostic (2.16e-1)" "unprognostic (2.59e-2)" "unprognostic (1.08e-1)" "unprognostic (5.64e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-1)" "unprognostic (1.27e-1)" "unprognostic (1.85e-1)" "unprognostic (6.72e-2)" "unprognostic (6.08e-3)" "unprognostic (1.75e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (6.78e-2)" 0.1 1.3 7.3 0.0 4.3 0.1 0.2 0.0 3.4 0.6 0.0 0.3 0.0 0.2 0.0 0.2 0.6 0.1 0.2 3.0 5.0 0.3 0.2 0.3 0.0 1.3 3.0 6.3 0.5 0.1 0.5 0.0 0.4 0.3 0.0 0.7 0.3 0.8 3.8 0.7 0.2 0.0 0.0 3.7 0.2 0.9 11.0 0.2 0.3 0.0 0.0 0.2 0.2 1.1 0.1 1.2 10.8 0.0 0.2 0.7 0.2 3.1 0.0 5.6 0.6 0.3 0.0 0.0 0.3 3.7 3.6 4.1 0.0 6.2 2.2 0.3 0.0 0.0 0.1 0.1 7.1 0.0 0.1 1.1 1.4 1.1 14.1 3.0 1.2 0.4 0.0 0.1 2.1 0.4 0.1 0.1 1.3 0.0 0.1 0.0 0.0 1.6 3.2 0.0 1.0 2.7 0.0 0.1 0.1 1.6 0.0 0.0 0.0 0.0 19.4 0.1 35.2 6.3 0.1 0.1 6.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.3 4.3 0.0 3.4 3.0 5.0 1.3 3.0 0.4 0.0 11.0 1.1 0.0 3.2 0.0 157.0 0.0 0.3 0.4 0.0 0.0 1.8 0.4 0.9 1.6 0.0 0.7 0.0 2.1 0.0 0.1 0.1 0.0 1.3 0.9 0.1 0.3 0.2 0.0 0.0 54.4 0.0 0.0 1.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 16.8 70.0 0.0 0.0 0.0 0.0 0.9 0.6 0.2 0.0 10.3 0.0 19.9 0.0 108.0 24.9 0.2 0.0 0.4 0.0 0.6 0.0 0.1 0.0 1.6 0.0 28.7 0.4 0.1 2.2 0.0 0.3 0.0 0.1 0.4 0.0 0.3 CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 235.9" "Cell type enhanced" "Detected in many" "Adipocytes: 311.9;Endothelial cells: 206.1;Hepatic stellate cells: 185.6;Late spermatids: 84.6;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 752.5;TIME: 655.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" 84.5 13.8 16.3 14.9 15.9 0.2 71.4 15.1 16.6 16.2 11.3 16.8 7.9 19.9 8.6 12.4 17.1 29.7 84.4 13.8 14.6 19.1 24.0 95.0 13.1 16.7 16.6 8.1 7.7 10.3 7.4 235.9 17.9 11.6 10.2 1.3 12.0 9.1 41.8 16.7 17.0 27.8 15.5 20.4 13.3 10.5 22.6 5.2 37.5 58.9 7.9 22.1 14.2 15.5 0.5 0.6 4.6 0.0 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 119.8 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 752.5 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 15.7 0.0 2.4 0.0 0.1 655.1 0.0 0.9 0.1 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.3 15.9 15.1 16.6 13.8 14.6 16.7 16.6 17.9 15.5 22.6 15.5 311.9 0.0 6.2 1.3 0.7 4.1 0.0 0.0 1.8 0.0 1.0 2.7 17.9 5.7 0.6 1.8 0.0 6.6 0.5 0.0 0.0 0.2 33.5 0.5 0.6 206.1 0.0 10.7 0.1 0.0 48.9 7.1 0.0 1.3 3.8 0.0 185.6 1.7 2.3 0.0 0.1 0.0 0.0 35.7 6.3 84.6 6.2 1.2 12.4 28.1 0.1 0.3 0.0 0.5 0.1 0.0 0.0 2.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 5.0 5.4 10.9 0.3 0.3 3.0 80.7 1.5 3.0 0.1 0.2 CDH6 ENSG00000113361 "Cadherin 6" P55285 5 31193686-31329146 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 14.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 48.6;Excitatory neurons: 67.1;Oligodendrocyte precursor cells: 60.8;Pancreatic endocrine cells: 63.8;Proximal tubular cells: 171.1;Sertoli cells: 46.0;Smooth muscle cells: 69.5" "Group enriched" "Detected in many" 5 "ovarian cancer: 15.0;renal cancer: 28.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "EFO-21: 477.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007047, HPA007403, HPA007456, CAB025274" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 9600000 "Cluster 21: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cell Junctions" "CAB025274: , HPA007047: AB_1078374, HPA007403: , HPA007456: AB_1078373" "unprognostic (3.87e-2)" "unprognostic (4.69e-2)" "unprognostic (1.35e-1)" "unprognostic (1.92e-3)" "unprognostic (1.58e-2)" "unprognostic (7.61e-3)" "unprognostic (9.04e-2)" "unprognostic (2.68e-1)" "unprognostic (2.74e-2)" "unprognostic (5.22e-2)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (8.29e-3)" "unprognostic (1.22e-3)" "unprognostic (2.67e-1)" "unprognostic (6.22e-2)" "unprognostic (2.09e-2)" 5.0 1.1 3.2 1.4 9.3 0.2 2.6 2.2 3.7 4.3 0.5 1.3 1.3 2.3 1.8 2.4 6.8 9.2 2.0 2.2 7.4 14.8 0.7 4.5 0.6 4.9 9.5 0.7 0.7 1.1 1.0 3.6 6.0 1.1 0.9 1.5 0.7 1.8 1.2 1.0 1.2 2.6 3.2 0.8 1.0 0.3 9.8 0.4 2.3 1.6 0.7 2.3 1.9 3.9 0.1 1.9 62.2 0.0 0.0 0.0 0.2 1.5 0.1 0.0 0.0 0.2 0.0 0.1 477.1 0.3 0.0 0.0 49.6 0.1 0.0 0.6 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 17.5 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.1 9.4 0.0 0.2 0.0 10.9 0.1 14.0 0.0 1.8 0.0 0.0 0.1 0.2 19.3 0.1 0.2 0.0 0.1 1.8 5.9 1.5 0.1 0.4 1.1 0.1 0.1 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 9.3 2.2 3.7 2.2 7.4 4.9 9.5 6.0 3.2 9.8 3.9 5.7 0.0 0.5 7.2 2.4 0.9 0.1 36.5 0.0 10.8 0.1 0.4 3.1 48.6 7.0 11.0 0.0 0.0 0.0 0.0 27.4 37.2 0.2 2.9 0.6 5.3 0.0 0.0 67.1 3.0 0.0 2.9 0.0 2.9 0.0 4.1 0.0 0.1 0.1 0.0 33.6 0.0 0.0 0.0 2.5 0.1 0.3 1.3 0.0 39.4 1.0 0.3 0.0 60.8 5.5 63.8 0.0 0.4 0.0 1.2 0.0 171.1 1.1 0.8 46.0 0.6 69.5 0.0 0.4 0.1 1.0 0.0 1.8 0.2 0.0 0.1 CDK16 "FLJ16665, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1" ENSG00000102225 "Cyclin dependent kinase 16" Q00536 X 47217860-47229997 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 217.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000974, HPA001366, CAB016535" Approved Approved "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Microtubules, Cytosol" "Plasma membrane" "CAB016535: AB_785112, HPA000974: AB_2666162, HPA001366: AB_1079584" "unprognostic (2.37e-3)" "unprognostic (6.93e-2)" "unprognostic (2.96e-2)" "unprognostic (1.16e-3)" "unprognostic (8.80e-2)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.02e-6)" "unprognostic (2.85e-1)" "unprognostic (5.59e-2)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.59e-2)" "unprognostic (1.83e-1)" "unprognostic (3.89e-3)" "unprognostic (2.55e-1)" 48.2 61.3 59.0 30.4 63.6 65.7 38.6 63.8 75.0 37.9 35.7 41.4 34.2 37.5 19.7 60.7 37.6 23.8 113.3 64.3 46.5 62.7 35.0 41.6 24.3 57.2 52.4 45.3 43.1 50.6 41.7 37.9 54.9 37.2 29.6 33.6 43.9 30.4 217.6 41.9 36.3 37.7 39.6 34.0 39.1 55.2 74.3 29.9 50.3 180.4 26.5 34.2 36.8 60.6 177.6 132.5 124.8 185.0 89.5 76.2 124.2 82.4 100.7 122.3 90.5 150.2 83.3 42.1 51.2 148.1 225.7 97.7 134.3 174.7 81.8 50.9 212.6 46.0 193.8 118.8 115.7 48.7 103.0 95.5 109.6 173.8 207.4 101.7 111.0 43.7 69.6 69.7 108.4 153.1 42.7 111.1 97.9 66.3 141.8 44.9 98.8 74.4 91.7 137.7 105.0 79.4 223.2 169.9 86.5 144.4 152.0 59.3 112.9 81.1 131.4 125.4 99.8 54.6 58.2 41.8 71.4 223.0 93.1 2.6 7.8 7.5 3.7 9.3 4.9 3.4 5.0 6.0 9.7 9.8 4.3 4.6 3.2 5.5 8.4 11.3 5.5 6.1 59.0 63.6 63.8 75.0 64.3 46.5 57.2 52.4 54.9 39.6 74.3 60.6 18.8 0.0 6.1 7.2 20.2 32.5 33.0 30.6 33.6 23.5 38.2 26.8 43.3 21.5 22.1 31.3 4.2 25.7 20.1 67.2 54.8 33.7 26.5 41.2 24.5 21.8 28.1 20.6 12.5 37.0 45.2 24.0 46.4 57.7 5.7 27.8 19.2 16.7 25.3 30.3 15.8 34.3 32.6 19.5 30.8 94.8 17.1 23.5 33.8 2.8 12.6 17.1 9.2 3.5 7.8 48.4 46.1 13.2 31.9 48.3 45.1 34.7 17.9 14.6 0.0 19.1 22.6 27.6 17.5 64.2 34.7 26.0 21.5 30.0 48.6 63.3 CDK5 PSSALRE ENSG00000164885 "Cyclin dependent kinase 5" Q00535 7 151053815-151057897 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Lissencephaly, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008909, HPA064535" Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB008909: , HPA064535: AB_2685280" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (4.22e-2)" "unprognostic (1.43e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-1)" "unprognostic (5.67e-3)" "unprognostic (1.05e-2)" "unprognostic (1.22e-1)" "unprognostic (5.78e-3)" "unprognostic (6.25e-3)" "unprognostic (3.35e-1)" "unprognostic (4.47e-2)" "unprognostic (1.46e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" "unprognostic (1.11e-1)" 6.3 16.8 50.2 9.4 53.2 11.2 8.6 44.9 65.8 8.6 40.0 9.3 10.9 6.7 24.9 10.2 8.2 9.5 9.8 57.5 50.9 13.5 12.5 8.3 9.8 48.6 45.3 4.5 9.5 22.8 14.7 8.6 48.4 8.8 9.9 11.3 9.6 10.2 8.5 9.5 8.6 10.4 43.2 9.4 7.9 4.9 50.1 14.2 10.0 7.2 11.6 8.8 6.0 50.9 31.9 40.8 37.3 59.7 48.8 36.1 17.8 24.4 41.7 47.9 40.3 31.2 31.0 34.7 71.3 31.8 63.5 23.5 67.8 40.6 22.6 24.9 43.3 38.2 32.4 30.7 31.6 29.0 64.4 37.9 28.7 39.0 13.5 62.8 38.8 57.6 36.3 24.0 50.7 68.4 76.4 57.9 39.3 57.2 80.5 38.9 14.8 41.5 46.2 27.9 23.0 97.8 30.9 37.7 43.8 36.0 18.6 25.9 22.7 42.2 10.3 31.2 39.2 52.1 61.4 13.7 66.4 46.5 75.8 18.9 39.4 20.1 13.5 46.2 11.1 13.3 12.8 13.6 44.7 12.8 9.8 11.8 5.7 19.9 36.4 26.9 31.9 23.8 50.2 53.2 44.9 65.8 57.5 50.9 48.6 45.3 48.4 43.2 50.1 50.9 7.6 0.0 6.0 1.6 6.2 3.6 8.2 18.0 6.2 12.1 9.6 10.4 3.1 8.6 14.7 11.0 2.1 26.8 5.4 8.0 39.2 21.4 0.8 14.9 10.9 8.9 9.0 12.2 5.8 18.9 12.3 7.6 9.7 9.3 30.5 23.6 7.9 11.1 41.9 0.0 6.4 8.9 18.3 21.9 6.2 1.3 4.7 16.6 10.6 1.9 19.9 12.6 12.3 1.5 3.7 22.8 15.0 11.3 12.4 4.3 20.2 35.7 14.4 7.1 6.6 4.5 13.1 3.9 11.2 11.4 6.3 9.0 7.3 14.2 9.5 9.0 CEACAM5 "CD66e, CEA" ENSG00000105388 "CEA cell adhesion molecule 5" P06731 19 41708585-41730433 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 981.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 1389.2;Intestinal goblet cells: 395.0;Paneth cells: 777.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 1007.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 56.9" "CAB000021, CAB000022, HPA011041, HPA019758" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 23000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB000021: , CAB000022: AB_2335697, HPA011041: AB_1078481, HPA019758: AB_1846326" "unprognostic (1.54e-2)" "unprognostic (7.59e-2)" "unprognostic (5.49e-3)" "unprognostic (1.80e-1)" "unprognostic (1.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.49e-1)" "unprognostic (2.11e-1)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (8.67e-9)" "unprognostic (2.92e-1)" "unprognostic (2.71e-2)" "unprognostic (6.31e-2)" "unprognostic (1.85e-1)" 3.2 0.1 0.0 185.6 0.0 0.2 4.0 0.3 0.1 38.5 0.2 981.2 22.7 1.3 0.2 232.0 0.8 0.8 0.1 0.1 0.0 0.9 0.2 30.2 0.1 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.5 942.7 0.0 29.2 3.3 0.1 3.5 61.4 28.7 0.0 0.1 163.2 0.3 0.1 0.2 1.0 0.0 36.9 10.4 71.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.1 0.0 0.0 13.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.3 56.9 1.1 0.2 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 32.1 4.1 0.0 2.7 0.0 1.0 12.3 0.0 0.0 0.1 0.0 0.4 0.0 34.8 0.0 0.0 0.0 0.0 1389.2 0.0 3.4 0.4 0.0 0.0 0.2 65.7 0.0 0.1 0.9 0.0 0.4 22.4 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.1 395.0 4.1 0.0 0.4 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 21.3 777.3 0.0 0.1 16.5 10.2 0.0 4.5 0.0 0.0 0.1 0.4 0.8 0.5 1.9 0.0 0.0 1.2 0.0 192.3 124.4 CEACAM7 "CEA, CGM2" ENSG00000007306 "CEA cell adhesion molecule 7" Q14002 19 41673303-41706976 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 651.8" "Group enriched" "Detected in some" 9 "Distal enterocytes: 1454.0;Paneth cells: 731.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 66.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA069621, HPA073910" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "HPA069621: AB_2686162, HPA073910: " "unprognostic (5.24e-2)" "unprognostic (2.72e-1)" "unprognostic (1.64e-2)" "unprognostic (6.03e-2)" "unprognostic (2.07e-2)" "unprognostic (4.30e-2)" "unprognostic (3.61e-2)" "unprognostic (1.74e-1)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (3.14e-1)" 0.6 0.0 0.0 71.4 0.0 0.1 2.9 0.0 0.0 13.3 0.0 595.8 0.5 0.3 0.0 52.6 0.6 39.4 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.4 651.8 0.0 4.0 0.8 0.1 1.4 0.7 5.7 0.0 0.2 2.0 0.1 0.0 0.0 0.0 0.0 12.0 23.4 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.2 0.9 0.0 0.0 0.1 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 1454.0 0.0 116.6 0.1 0.0 0.0 0.5 8.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 1.0 731.2 0.0 0.0 1.4 0.0 0.0 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 38.4 30.3 CFLAR "c-FLIP, CASH, CASP8AP1, Casper, cFLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT" ENSG00000003402 "CASP8 and FADD like apoptosis regulator" O15519 2 201116154-201176687 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 609.9;Urothelial cells: 521.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 392.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 392.6" "Cell line enhanced" "Detected in all" "U-266/70: 214.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019044, CAB022157, CAB025216" Uncertain Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane, Cytosol" "Nuclear bodies" "CAB022157: , CAB025216: , HPA019044: AB_10696204" "unprognostic (4.61e-2)" "unprognostic (5.32e-2)" "unprognostic (2.49e-1)" "unprognostic (1.44e-1)" "unprognostic (2.95e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.46e-2)" "unprognostic (9.01e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (3.08e-2)" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (7.83e-2)" "unprognostic (9.13e-2)" "unprognostic (6.84e-2)" "unprognostic (2.24e-2)" 122.4 50.6 38.8 103.9 40.9 247.6 83.1 54.1 47.4 57.0 75.6 86.0 59.2 57.9 60.6 68.0 66.6 71.6 184.8 39.4 32.7 57.5 59.2 174.6 91.1 46.5 40.5 38.3 40.7 31.8 29.4 94.0 42.1 65.6 56.4 12.4 58.0 63.2 222.8 51.0 64.8 58.8 36.6 98.1 56.5 25.3 51.9 54.1 78.8 89.2 107.3 78.7 61.7 46.1 21.5 42.9 30.0 17.9 92.3 71.0 37.5 53.6 92.1 34.3 41.6 50.4 78.4 5.8 49.6 62.5 41.6 15.5 9.8 40.3 53.9 160.7 29.9 32.3 38.4 82.2 63.6 24.2 102.2 76.8 39.6 58.2 50.3 41.7 176.7 7.3 110.8 131.2 63.1 17.9 11.3 96.3 10.2 17.2 32.7 11.7 7.2 46.5 42.5 44.0 6.6 11.8 35.7 31.2 43.2 19.6 22.1 44.8 193.6 71.0 29.5 26.7 26.1 214.6 76.2 35.9 50.6 19.5 36.3 91.8 60.3 70.3 54.4 61.8 48.4 25.6 46.5 52.1 33.4 20.9 29.5 38.3 392.6 45.2 68.5 23.0 60.7 42.0 38.8 40.9 54.1 47.4 39.4 32.7 46.5 40.5 42.1 36.6 51.9 46.1 191.3 451.9 234.9 30.3 126.4 54.8 229.6 164.9 29.0 10.9 38.9 30.0 205.8 102.9 206.7 69.9 31.3 77.2 166.2 132.5 74.3 148.8 83.3 202.8 75.0 261.0 95.1 59.1 6.9 72.5 34.8 89.5 73.4 219.2 81.6 93.4 201.0 97.5 68.6 13.5 16.8 76.8 40.7 123.2 609.9 44.8 51.9 278.0 97.8 146.1 247.0 23.4 276.0 29.7 56.8 166.4 155.6 49.7 317.8 386.0 116.7 101.5 276.1 30.7 39.5 113.2 77.9 14.4 12.2 33.2 86.1 70.1 168.3 56.1 50.9 521.3 CGN KIAA1319 ENSG00000143375 Cingulin Q9P2M7 1 151510510-151538692 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 56.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 118.6;Distal enterocytes: 173.2;Paneth cells: 108.7;Proximal enterocytes: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 91.4;CAPAN-2: 59.1;OE19: 58.6;RT4: 44.0" "Low region specificity" "Detected in many" "CAB017193, HPA027586, HPA027587, HPA027657" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB017193: , HPA027586: AB_10600208, HPA027587: AB_10601884, HPA027657: AB_10611527" "unprognostic (1.57e-1)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (8.74e-3)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (8.38e-2)" "unprognostic (4.61e-1)" "unprognostic (2.11e-2)" "unprognostic (2.96e-3)" "unprognostic (7.10e-2)" "prognostic favorable (5.84e-10)" "unprognostic (2.66e-1)" "unprognostic (3.00e-1)" "unprognostic (8.28e-2)" "unprognostic (2.10e-2)" 5.8 1.1 1.9 6.0 3.3 0.4 9.0 8.5 3.3 4.9 6.5 37.2 52.7 1.4 1.5 8.6 13.2 13.6 0.6 2.0 3.7 12.2 32.1 27.3 0.4 5.5 3.0 2.0 24.2 32.1 3.7 1.6 5.6 10.1 25.1 3.7 21.1 7.0 0.2 17.9 56.4 1.5 1.7 0.4 30.4 6.6 3.4 0.7 4.9 0.1 2.3 8.3 6.2 6.7 28.9 3.2 2.7 4.6 0.0 0.0 35.4 0.1 0.1 0.8 0.9 91.4 59.1 1.3 9.4 0.0 4.9 27.0 8.6 5.0 0.6 17.3 6.0 2.4 1.3 1.8 0.0 0.4 3.6 0.0 1.0 1.3 0.7 0.0 0.3 7.8 1.2 8.1 0.0 26.8 5.0 0.6 22.9 58.6 2.5 5.4 2.8 4.3 17.9 44.0 8.9 4.4 1.8 27.1 1.0 10.3 33.5 0.3 0.5 0.3 8.3 0.5 1.2 7.7 8.4 5.2 0.3 3.3 2.4 0.2 0.1 0.0 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.0 1.9 3.3 8.5 3.3 2.0 3.7 5.5 3.0 5.6 1.7 3.4 6.7 0.1 118.6 33.3 2.3 0.2 0.3 3.3 5.9 0.6 4.3 14.9 9.1 0.7 24.3 22.4 3.7 0.0 3.5 0.5 173.2 0.0 21.5 0.3 13.8 2.1 0.6 10.3 2.7 0.8 25.4 0.3 2.3 54.6 27.3 0.0 0.5 0.0 29.6 0.3 0.0 10.4 32.7 8.2 0.0 0.4 1.2 0.6 0.5 3.6 0.0 2.1 13.5 0.0 3.5 11.7 49.5 108.7 0.7 0.5 11.9 88.7 3.0 46.8 1.5 0.0 0.1 1.0 1.5 6.9 4.2 1.8 0.4 0.6 1.8 27.2 18.3 CHRM3 ENSG00000133019 "Cholinergic receptor muscarinic 3" P20309 1 239386565-239915452 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8;salivary gland: 17.5" "Group enriched" "Detected in many" 28 "Excitatory neurons: 802.9;Inhibitory neurons: 624.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 17.2;SH-SY5Y: 53.5;U-266/70: 21.7;U-266/84: 16.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024106, HPA048036" Approved Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA024106: AB_1854211, HPA048036: AB_2680238" "unprognostic (1.63e-1)" "unprognostic (4.82e-2)" "unprognostic (1.05e-1)" "unprognostic (4.11e-3)" "unprognostic (3.48e-3)" "unprognostic (5.81e-2)" "unprognostic (2.30e-3)" "unprognostic (5.18e-2)" "unprognostic (1.71e-1)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" "unprognostic (6.44e-2)" "unprognostic (5.34e-4)" "unprognostic (3.04e-2)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "unprognostic (4.88e-2)" 0.3 0.4 4.6 0.8 7.3 0.2 0.8 0.0 11.8 0.4 0.0 7.0 1.4 1.9 0.4 7.5 0.8 0.7 0.4 7.5 0.0 1.1 0.4 1.1 0.1 0.0 0.0 4.8 10.6 0.5 0.5 0.8 0.0 1.1 2.8 1.7 17.5 3.0 0.0 1.3 1.5 4.1 0.0 0.7 5.0 2.5 4.1 0.1 2.0 0.1 0.1 7.0 0.4 2.9 0.0 0.1 0.4 0.4 0.0 0.0 0.9 0.6 0.1 0.3 0.1 0.0 0.0 0.0 2.1 0.0 0.0 5.8 0.6 3.8 2.7 0.0 3.7 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 1.1 9.1 0.9 1.4 0.0 0.0 4.6 4.6 9.1 0.0 1.1 17.2 0.7 0.8 0.1 53.5 0.0 0.1 0.1 4.0 1.8 0.0 0.3 2.3 0.8 0.1 0.5 21.7 16.3 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 7.3 0.0 11.8 7.5 0.0 0.0 0.0 0.0 0.0 4.1 2.9 6.1 0.0 3.7 6.2 0.0 0.0 2.1 0.0 0.6 19.0 4.6 3.2 1.2 0.0 0.8 0.0 0.0 3.2 0.3 11.0 1.9 0.4 19.6 0.1 0.1 3.0 3.5 4.6 802.9 17.3 0.7 3.9 11.7 0.2 1.3 7.5 4.2 0.3 0.5 0.0 624.0 6.0 0.0 0.0 0.0 3.9 0.0 0.2 7.2 22.5 0.0 0.3 0.0 8.5 11.2 2.6 25.3 0.4 0.2 2.5 2.2 1.4 1.6 0.6 0.0 0.2 1.1 12.9 3.0 0.2 0.0 0.5 0.1 0.8 15.5 0.2 CHRNA1 CHRNA ENSG00000138435 "Cholinergic receptor nicotinic alpha 1 subunit" P02708 2 174747592-174787935 "Disease related genes, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skeletal muscle: 170.1" "Cell type enriched" "Detected in some" 48 "Skeletal myocytes: 193.5" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Group enriched" "Detected in some" 13 "cerebral cortex: 12.8;hippocampal formation: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "LHCN-M2: 445.4;RH-30: 360.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071554 Enhanced Supported "Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA071554: AB_2686416" "unprognostic (1.49e-1)" "unprognostic (1.97e-1)" "unprognostic (1.22e-3)" "unprognostic (2.28e-2)" "unprognostic (2.96e-1)" "unprognostic (8.55e-3)" "unprognostic (5.34e-2)" "unprognostic (5.29e-3)" "unprognostic (9.59e-2)" "unprognostic (9.64e-2)" "unprognostic (9.66e-2)" "unprognostic (6.37e-2)" "unprognostic (4.18e-4)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" "unprognostic (1.86e-1)" "unprognostic (7.18e-2)" 0.2 0.0 0.2 0.2 0.4 0.0 0.5 0.1 12.8 0.6 0.2 1.5 0.2 0.0 0.2 0.6 0.0 0.0 0.3 5.5 0.2 0.0 0.2 0.6 0.8 0.5 0.2 0.0 0.0 0.0 3.3 0.2 0.5 2.0 0.9 0.0 3.2 0.0 170.1 0.5 0.0 0.0 0.3 0.0 0.0 0.4 0.3 1.1 0.0 20.4 1.2 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 21.5 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.2 445.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 360.2 0.0 0.0 0.3 2.9 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.4 0.1 12.8 5.5 0.2 0.5 0.2 0.5 0.3 0.3 0.7 0.1 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 4.0 0.0 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.5 0.0 0.6 0.4 1.7 0.3 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 193.5 0.3 0.1 0.2 0.0 0.0 0.0 1.8 0.0 0.2 0.0 CHRNA2 ENSG00000120903 "Cholinergic receptor nicotinic alpha 2 subunit" Q15822 8 27459756-27479883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 72.1;prostate: 29.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.5;Inhibitory neurons: 14.8;Prostatic glandular cells: 2.4;Theca cells: 3.4" "Cancer enriched" "Detected in single" 421 "prostate cancer: 30.2" "Region enhanced" "Detected in many" "thalamus: 72.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA048348 Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge" "HPA048348: " "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (2.23e-2)" "unprognostic (3.19e-1)" "unprognostic (6.19e-2)" "unprognostic (6.29e-3)" "unprognostic (1.19e-2)" "unprognostic (2.13e-1)" "unprognostic (1.91e-1)" "unprognostic (7.60e-2)" "unprognostic (1.70e-1)" "unprognostic (1.47e-1)" 0.0 0.5 15.8 0.2 5.5 0.9 1.4 38.1 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 8.0 0.0 0.0 0.2 0.1 15.7 21.5 0.0 0.2 0.0 0.3 0.0 3.5 29.0 0.0 3.7 0.0 0.0 0.1 0.2 0.2 0.0 2.3 0.1 0.0 0.0 72.1 2.9 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 15.8 5.5 38.1 2.9 0.7 8.0 15.7 21.5 3.5 2.3 72.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 CHRNA3 ENSG00000080644 "Cholinergic receptor nicotinic alpha 3 subunit" P32297 15 78593052-78621295 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 39.3;lymphoid tissue: 65.8;retina: 53.5" "Cell type enriched" "Detected in some" 19 "Cone photoreceptor cells: 164.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 356.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029430 Enhanced Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Nuclear speckles" "HPA029430: AB_10603785" "unprognostic (2.28e-1)" "unprognostic (3.45e-1)" "unprognostic (2.58e-2)" "unprognostic (2.36e-1)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" "unprognostic (9.16e-3)" "unprognostic (1.97e-1)" "unprognostic (4.28e-2)" "unprognostic (7.20e-2)" "unprognostic (3.12e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-4)" "unprognostic (2.65e-3)" "unprognostic (2.76e-1)" "unprognostic (1.53e-1)" "unprognostic (4.48e-1)" 0.3 39.3 4.4 5.1 2.0 0.0 0.1 6.3 1.0 1.0 0.3 8.1 1.5 0.5 0.0 0.1 0.0 0.3 0.4 0.7 2.3 0.0 0.0 0.2 0.3 3.1 6.4 0.1 0.2 0.0 1.1 0.1 10.0 0.2 4.0 53.5 0.1 0.0 0.1 0.7 3.0 3.7 0.3 0.1 2.8 1.0 9.2 65.8 0.2 0.0 0.8 0.2 0.7 1.0 0.1 0.3 0.7 0.6 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 1.5 0.0 8.8 0.0 0.0 0.3 1.4 0.5 0.4 0.1 0.0 0.1 4.0 0.0 0.3 0.0 0.0 0.0 0.0 22.6 0.2 0.0 0.0 0.3 7.1 0.0 1.6 0.1 0.2 0.4 0.3 0.1 0.0 0.4 67.7 356.1 0.3 0.1 0.1 0.5 0.4 0.0 0.0 0.1 1.7 0.1 0.4 0.2 0.7 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 2.0 6.3 1.0 0.7 2.3 3.1 6.4 10.0 0.3 9.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.8 0.0 0.0 0.0 164.7 0.0 0.0 0.2 1.9 0.0 3.7 0.1 1.2 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.7 0.4 3.6 0.0 0.0 0.0 3.5 0.0 0.2 0.0 0.0 0.0 3.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.1 0.1 0.3 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.1 CHRNA5 ENSG00000169684 "Cholinergic receptor nicotinic alpha 5 subunit" P30532 15 78565520-78595269 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 13.0;Extravillous trophoblasts: 11.5;Intestinal goblet cells: 9.8;Spermatocytes: 12.4;Spermatogonia: 28.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA054381 Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Focal adhesion sites" "Plasma membrane" "HPA054381: AB_2682468" "unprognostic (2.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" "unprognostic (3.20e-3)" "unprognostic (6.66e-2)" "unprognostic (1.29e-3)" "unprognostic (7.03e-5)" "prognostic unfavorable (3.64e-5)" "unprognostic (1.34e-2)" "unprognostic (1.31e-2)" "unprognostic (4.52e-2)" "unprognostic (8.97e-2)" "unprognostic (6.50e-11)" "unprognostic (4.37e-1)" "unprognostic (5.39e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" 0.8 2.0 1.9 1.9 1.8 0.5 1.5 2.7 3.0 1.0 2.0 4.0 4.8 1.3 1.1 1.6 0.5 4.4 1.3 1.7 1.8 0.3 0.3 0.5 0.7 1.7 2.2 0.7 1.9 0.3 0.2 1.1 2.4 1.9 4.2 2.5 0.7 0.4 3.9 0.6 2.4 2.1 1.6 0.3 2.8 3.1 2.4 0.7 0.3 0.5 1.1 1.8 1.1 2.7 16.5 41.8 22.4 12.5 2.7 1.9 9.1 12.0 5.8 13.0 23.4 16.1 76.7 9.8 28.6 2.6 34.7 14.3 43.5 17.6 13.2 20.1 51.9 18.3 29.5 16.2 1.4 12.4 24.7 0.7 3.1 3.5 4.7 4.8 24.5 13.6 18.2 12.5 8.3 36.1 15.9 4.3 18.2 32.4 11.5 20.1 25.8 9.9 15.7 39.2 37.7 55.0 28.6 27.5 14.1 12.7 61.2 3.2 5.3 17.6 21.0 13.0 38.0 14.3 63.4 11.3 10.6 19.8 16.5 1.0 0.4 0.7 0.1 0.4 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.3 0.7 0.3 0.4 0.2 0.0 0.1 1.9 1.8 2.7 3.0 1.7 1.8 1.7 2.2 2.4 1.6 2.4 2.7 0.9 0.0 0.0 0.3 1.4 3.2 13.0 0.5 8.6 7.6 1.2 2.9 1.2 2.8 0.2 0.0 0.0 2.6 0.4 1.2 0.0 0.3 1.2 0.5 0.6 2.0 3.5 0.8 1.0 2.0 11.5 1.0 0.5 0.6 0.0 1.5 0.0 0.3 1.0 5.0 1.1 9.8 0.0 0.0 2.3 2.6 0.3 0.8 1.8 0.0 0.2 0.4 1.0 0.5 0.9 0.7 0.1 0.4 0.9 6.7 0.1 0.4 0.1 0.7 0.0 1.3 1.6 12.4 28.8 2.9 1.6 1.0 2.0 0.2 2.1 3.2 CHRND ACHRD ENSG00000135902 "Cholinergic receptor nicotinic delta subunit" Q07001 2 232525993-232536667 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skeletal muscle: 57.6" "Group enriched" "Detected in some" 10 "Muller glia cells: 4.0;Skeletal myocytes: 4.4" "Cancer enriched" "Detected in single" 7 "head and neck cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 49 "RH-30: 99.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA056404, HPA065404" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA056404: AB_2732603, HPA065404: AB_2732734" "unprognostic (1.69e-2)" "unprognostic (7.93e-2)" "unprognostic (3.28e-3)" "unprognostic (7.75e-3)" "unprognostic (6.04e-2)" "unprognostic (1.10e-1)" "unprognostic (7.25e-2)" "unprognostic (1.90e-1)" "unprognostic (4.97e-8)" "unprognostic (7.52e-2)" "unprognostic (2.86e-1)" "unprognostic (2.46e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 6.3 0.7 0.0 57.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 6.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 99.4 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CIB1 "CIB, KIP, SIP2-28" ENSG00000185043 "Calcium and integrin binding 1" Q99828 15 90229975-90234047 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Angiogenesis, Apoptosis, Cell adhesion, Cell cycle, Cell division, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1385.8;Respiratory ciliated cells: 1103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012991, HPA042413, HPA048825" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane" "CAB012991: AB_2533205, HPA042413: AB_2732498, HPA048825: AB_2680533" "unprognostic (1.20e-1)" "unprognostic (1.59e-1)" "unprognostic (1.73e-2)" "prognostic favorable (2.26e-5)" "unprognostic (7.56e-2)" "unprognostic (5.51e-2)" "unprognostic (1.21e-2)" "unprognostic (8.29e-3)" "unprognostic (1.77e-1)" "unprognostic (4.09e-2)" "unprognostic (5.25e-3)" "unprognostic (2.44e-1)" "unprognostic (1.29e-3)" "unprognostic (1.85e-1)" "unprognostic (6.31e-2)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" 65.6 163.6 65.4 79.7 69.2 205.5 67.4 67.8 76.5 93.8 96.7 147.9 130.1 44.6 88.1 127.3 146.6 77.4 101.9 62.7 68.8 220.1 195.7 86.7 97.0 70.1 70.3 43.9 214.1 98.3 93.0 38.0 68.7 127.6 138.1 29.1 116.6 72.7 58.8 40.4 128.5 45.3 69.3 117.0 99.3 113.8 69.2 64.4 89.1 42.3 120.9 93.7 68.3 69.3 119.5 261.4 23.8 83.7 98.7 102.7 38.9 123.8 107.2 99.6 87.2 104.7 207.4 34.7 129.7 144.0 125.7 124.2 48.0 141.8 54.0 81.9 114.2 77.5 182.3 175.9 96.2 155.2 71.4 72.2 84.9 91.9 64.6 113.7 129.1 83.7 105.8 53.5 76.4 233.3 118.4 179.4 36.7 223.9 134.0 66.1 62.8 139.7 256.1 199.4 18.7 22.8 168.7 136.5 135.7 41.5 105.3 93.3 81.7 109.6 77.0 132.0 153.2 73.0 122.0 40.3 176.1 174.9 47.8 168.9 201.8 271.3 226.9 248.9 188.0 476.4 269.9 249.4 224.4 418.0 221.5 218.0 118.2 205.7 230.0 149.7 245.8 399.6 65.4 69.2 67.8 76.5 62.7 68.8 70.1 70.3 68.7 69.3 69.2 69.3 77.4 89.8 104.2 14.7 203.7 85.7 253.6 520.1 84.8 12.0 152.0 118.5 86.9 128.7 469.1 183.9 10.4 106.7 198.7 670.9 453.9 372.1 380.8 480.8 101.3 83.9 97.1 62.3 7.7 662.9 117.6 96.5 149.9 222.8 138.8 66.9 79.6 230.1 209.0 3.3 6.6 379.5 463.9 102.5 148.0 1385.8 105.3 180.5 128.1 4.7 187.5 138.4 184.4 5.0 12.2 620.2 794.2 92.6 88.8 699.6 661.4 668.6 1103.6 25.5 39.5 62.3 140.4 160.3 69.0 218.1 67.3 66.1 227.5 91.8 315.5 577.8 CLCA2 CLCRG2 ENSG00000137975 "Chloride channel accessory 2" Q9UQC9 1 86424171-86456553 "Predicted membrane proteins" "Cell adhesion, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 117.5;skin 1: 88.7;vagina: 53.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 47.4;Basal respiratory cells: 57.5;Basal squamous epithelial cells: 39.9;Club cells: 37.1;Early spermatids: 30.2;Squamous epithelial cells: 167.1;Suprabasal keratinocytes: 54.8;Urothelial cells: 52.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 146.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "hTCEpi: 210.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047192 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 96000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA047192: AB_2679977" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (3.96e-3)" "unprognostic (6.99e-2)" "unprognostic (6.33e-2)" "unprognostic (1.40e-1)" "unprognostic (6.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.26e-1)" "unprognostic (2.73e-1)" "unprognostic (9.99e-3)" "unprognostic (1.97e-8)" "unprognostic (3.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" 0.8 0.1 0.2 0.1 0.6 0.0 4.6 0.4 0.5 22.8 0.1 0.6 0.2 0.0 0.5 117.5 0.2 0.1 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.7 0.4 2.4 0.7 0.0 13.2 0.2 0.2 88.7 0.8 0.0 0.4 0.0 0.1 0.6 0.3 1.0 0.0 0.0 26.0 21.2 53.1 1.0 0.0 0.0 0.0 0.0 0.6 3.0 38.9 1.7 2.7 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 9.7 0.0 33.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 210.8 1.0 10.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.9 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.4 0.5 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.7 0.0 47.4 13.1 57.5 39.9 0.0 7.7 2.8 0.4 0.0 37.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 5.3 4.1 0.0 3.1 4.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 2.5 2.1 0.3 0.0 8.0 0.0 0.0 0.0 0.6 0.2 0.0 167.1 54.8 0.1 0.5 0.0 0.1 52.9 CLCN5 "ClC-5, CLC5, DENTS, hCIC-K2, hClC-K2, NPHL1, NPHL2, XLRH, XRN" ENSG00000171365 "Chloride voltage-gated channel 5" P51795 X 49922596-50099235 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "epididymis: 23.7;kidney: 46.2;liver: 16.9" "Cell type enriched" "Detected in many" 4 "Skeletal myocytes: 214.4" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.6;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in all" 4 "CACO-2: 49.0;RH-30: 66.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000401, HPA003213" Uncertain Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Plasma membrane" Cytosol "HPA000401: AB_1078531, HPA003213: AB_2666843" "unprognostic (3.33e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.57e-1)" "unprognostic (7.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.54e-1)" "unprognostic (8.08e-3)" "unprognostic (1.60e-1)" "unprognostic (5.21e-2)" "prognostic favorable (5.20e-4)" "unprognostic (3.59e-2)" "prognostic favorable (2.05e-8)" "unprognostic (7.87e-3)" "unprognostic (1.07e-1)" "unprognostic (1.25e-1)" "unprognostic (3.60e-2)" 2.1 2.5 1.7 1.7 1.9 1.5 1.6 3.8 1.6 1.8 2.5 2.4 4.9 4.0 23.7 2.4 3.0 3.9 1.3 1.5 2.9 46.2 16.9 2.8 1.3 3.2 3.2 7.0 2.1 1.4 2.3 5.8 3.7 1.7 2.8 3.4 2.5 1.0 4.0 4.8 3.8 2.9 2.5 1.8 2.9 2.1 2.7 1.1 2.2 2.8 1.2 1.4 2.0 2.3 2.9 5.4 4.2 5.5 12.8 7.5 7.9 2.8 1.2 1.6 1.9 49.0 3.0 3.5 1.2 2.5 9.7 2.8 9.9 1.7 2.2 1.1 7.5 3.3 2.7 12.8 7.2 4.1 5.7 4.9 1.6 3.7 5.9 1.2 5.8 4.0 4.3 4.7 5.3 3.2 1.6 1.4 5.7 7.4 2.4 1.9 66.0 5.2 6.0 5.5 7.2 5.2 3.3 3.0 5.1 14.1 3.0 2.1 3.8 1.6 3.7 12.7 1.4 3.6 11.9 7.3 2.8 6.6 8.5 0.0 0.9 0.0 0.1 0.9 0.1 0.1 0.2 0.2 2.6 0.1 0.0 0.0 0.2 0.1 0.1 2.8 0.0 0.3 1.7 1.9 3.8 1.6 1.5 2.9 3.2 3.2 3.7 2.5 2.7 2.3 4.3 9.6 8.4 20.5 2.1 7.1 1.8 1.6 5.2 27.4 1.8 1.4 1.9 2.8 2.3 12.9 2.1 6.2 17.7 11.3 11.7 4.1 2.0 8.0 10.0 5.5 0.0 3.4 11.5 3.5 2.6 7.9 8.6 22.8 2.5 0.8 1.4 35.2 11.1 8.4 15.6 6.6 4.1 17.6 19.8 0.6 5.3 10.9 3.6 46.9 10.1 2.7 2.1 20.6 9.6 7.7 7.3 13.2 2.2 4.0 20.4 38.8 4.2 4.3 0.0 214.4 4.8 0.9 2.3 8.1 9.5 5.1 1.9 9.3 7.0 4.8 CLDN4 "CPE-R, CPETR, CPETR1, hCPE-R, WBSCR8" ENSG00000189143 "Claudin 4" O14493 7 73799542-73832690 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 305.0;urinary bladder: 303.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 3149.1;Glandular and luminal cells: 2298.8;Paneth cells: 2081.0;Prostatic glandular cells: 2184.8;Urothelial cells: 8033.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 358.1;BEWO: 395.0;CAPAN-2: 761.4;MCF7: 400.2;OE19: 402.0;PC-3: 495.0;RT4: 340.2;SK-BR-3: 636.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB002610 Enhanced Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "CAB002610: " "unprognostic (1.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.25e-1)" "unprognostic (1.23e-2)" "unprognostic (1.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (7.09e-2)" "unprognostic (3.07e-1)" "prognostic unfavorable (3.28e-4)" "unprognostic (2.16e-3)" "unprognostic (5.11e-1)" "prognostic favorable (3.46e-10)" "unprognostic (5.77e-2)" "unprognostic (1.37e-1)" "unprognostic (9.38e-2)" "unprognostic (4.63e-2)" 2.6 0.4 0.1 23.0 0.0 0.2 69.0 0.8 0.3 61.2 4.8 256.3 126.9 26.7 24.4 305.0 75.8 48.9 0.4 0.2 0.0 116.2 4.8 64.0 1.0 0.4 1.5 1.2 116.2 51.9 13.1 36.3 0.3 82.2 123.3 0.3 204.6 39.1 0.5 180.8 190.6 7.3 0.0 0.7 13.3 0.6 0.2 10.7 111.7 0.3 37.5 303.5 105.7 0.0 358.1 4.4 0.0 1.5 0.0 0.4 395.0 3.3 0.2 0.3 0.4 184.9 761.4 0.6 28.0 0.1 2.6 193.3 0.0 0.5 0.4 0.7 0.4 0.2 20.3 127.0 0.1 0.1 0.9 0.0 1.9 0.1 0.4 0.3 0.0 0.2 0.3 0.7 0.0 400.2 0.7 1.9 0.7 402.0 495.0 0.5 6.9 7.6 92.4 340.2 79.5 1.7 0.4 636.8 0.8 21.6 250.9 0.9 0.5 0.9 13.7 3.1 3.5 0.9 0.7 0.7 0.6 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.3 0.2 0.0 0.4 1.5 0.3 0.0 0.2 0.0 5.1 275.7 230.2 0.0 12.2 16.2 3149.1 641.6 31.3 0.4 1255.2 548.4 0.8 287.4 954.3 218.8 0.0 771.7 18.7 1985.0 13.7 1026.1 0.0 1201.7 231.0 41.3 675.5 0.0 0.2 447.1 739.7 27.0 94.8 2298.8 27.3 0.2 0.4 0.5 76.3 0.0 0.1 1266.9 905.3 0.6 8.6 0.0 2.5 29.3 14.2 0.0 15.6 0.8 0.0 0.0 0.0 950.2 2081.0 0.0 2.5 2184.8 1906.1 21.6 635.6 0.0 0.0 0.1 68.2 0.0 0.2 1068.1 54.0 956.1 40.7 0.1 965.1 8033.4 CLEC5A "CLECSF5, MDL-1" ENSG00000258227 "C-type lectin domain containing 5A" Q9NY25 7 141927357-141947007 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 41.3" "Group enriched" "Detected in some" 6 "Hofbauer cells: 18.0;Langerhans cells: 67.5;Macrophages: 58.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "classical monocyte: 9.1" "Lineage enriched" "Detected in many" 8 "monocytes: 9.1" "Group enriched" "Detected in some" 23 "HL-60: 40.9;U-937: 157.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA054137 Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA054137: AB_2732582" "unprognostic (6.89e-2)" "unprognostic (1.07e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" "unprognostic (1.69e-2)" "unprognostic (4.56e-2)" "unprognostic (1.33e-5)" "unprognostic (4.57e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.58e-3)" "unprognostic (1.06e-1)" "unprognostic (1.73e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.23e-2)" "unprognostic (1.64e-1)" 1.1 1.8 1.1 7.3 1.2 41.3 0.6 1.3 2.6 0.7 2.1 0.2 0.1 0.3 0.0 1.2 0.5 1.8 0.5 1.0 3.3 0.5 1.8 4.0 0.1 2.2 3.3 0.3 1.3 1.2 0.5 0.9 2.2 0.4 0.3 1.0 1.2 0.5 0.0 2.6 0.0 1.3 1.6 1.1 0.2 0.5 4.9 0.6 0.7 0.0 0.1 2.3 0.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 157.3 0.0 0.0 9.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 1.8 1.1 1.2 1.3 2.6 1.0 3.3 2.2 3.3 2.2 1.6 4.9 2.4 0.1 0.0 4.8 0.7 0.6 1.9 0.0 0.0 0.0 0.2 0.1 0.1 0.3 1.5 5.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 3.5 0.0 0.0 0.1 0.0 0.2 0.8 0.0 0.0 2.5 0.0 0.0 0.0 18.0 0.0 0.2 0.0 0.0 4.7 67.5 0.7 0.0 58.1 1.8 7.5 6.4 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.9 0.4 0.0 0.0 0.2 0.0 0.1 0.0 1.4 0.3 0.4 0.0 0.0 0.0 CLECL1 DCAL1 ENSG00000184293 "C-type lectin like 1" Q8IZS7 12 9715860-9733299 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 9.9;lymphoid tissue: 31.1" "Group enriched" "Detected in some" 4 "B-cells: 87.0;dendritic cells: 24.0;Hofbauer cells: 22.2;Kupffer cells: 82.3;Langerhans cells: 64.6;Macrophages: 23.9;monocytes: 55.9;Plasma cells: 42.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 120.9" "Lineage enriched" "Detected in many" 5 "B-cells: 120.9" "Group enriched" "Detected in some" 5 "HEL: 49.7;Karpas-707: 66.2;U-698: 173.0;U-937: 95.6" "Low region specificity" "Detected in many" HPA063928 Supported "Plasma membrane,Centriolar satellite" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Centriolar satellite" "HPA063928: " "unprognostic (2.18e-2)" "unprognostic (2.35e-3)" "unprognostic (2.20e-3)" "unprognostic (1.90e-3)" "unprognostic (3.66e-1)" "unprognostic (1.90e-3)" "unprognostic (2.83e-1)" "unprognostic (7.55e-4)" "unprognostic (5.10e-2)" "unprognostic (2.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.20e-1)" "unprognostic (3.91e-5)" "unprognostic (3.31e-1)" "unprognostic (2.45e-1)" "unprognostic (6.10e-2)" "unprognostic (7.39e-2)" 1.0 1.6 0.6 9.9 0.9 1.9 2.0 1.4 0.9 0.9 1.3 3.0 2.7 0.9 0.0 0.7 0.8 2.5 0.4 0.6 0.9 0.7 2.1 2.1 24.8 1.8 1.1 0.5 0.2 0.3 0.3 0.7 1.4 0.7 4.3 0.1 1.3 0.5 0.1 0.4 9.9 1.8 1.2 16.2 4.5 0.9 1.1 5.2 0.6 0.2 31.1 3.0 0.3 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.7 0.0 0.0 0.0 18.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.2 0.0 0.1 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.1 0.2 1.2 173.0 0.0 95.6 0.0 2.4 7.9 0.4 4.5 14.4 0.1 120.9 3.9 9.7 18.7 54.3 0.2 1.4 0.3 0.3 15.5 25.4 0.2 5.2 0.6 0.9 1.4 0.9 0.6 0.9 1.8 1.1 1.4 1.2 1.1 1.6 0.3 0.0 0.0 0.0 87.0 2.0 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.0 1.8 0.0 0.0 0.1 24.0 0.1 0.0 0.0 1.0 0.1 0.1 0.3 0.0 4.4 0.0 0.2 0.1 0.6 0.0 0.1 5.1 0.0 0.4 0.4 22.2 0.0 0.0 0.2 0.0 82.3 64.6 1.4 0.3 23.9 12.4 1.0 55.9 0.0 1.0 0.0 0.0 0.0 0.0 0.0 42.0 0.0 0.0 0.4 0.0 0.0 6.6 0.1 0.1 0.0 0.2 0.1 1.8 0.3 11.2 0.0 0.0 0.1 CLIC2 "CLCNL2, XAP121" ENSG00000155962 "Chloride intracellular channel 2" O15247 X 155276211-155334657 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 51.2;Alveolar cells type 1: 89.8;Alveolar cells type 2: 54.9;Endothelial cells: 60.4;Erythroid cells: 70.7;Kupffer cells: 73.5;Langerhans cells: 135.0;monocytes: 71.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 18.6;myeloid DC: 47.9;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 16 "dendritic cells: 47.9;monocytes: 18.6" "Group enriched" "Detected in some" 5 "HDLM-2: 103.3;K-562: 60.4;Karpas-707: 53.4;RPMI-8226: 92.2" "Low region specificity" "Detected in all" "HPA047381, HPA060101" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 150000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA047381: AB_2680022, HPA060101: AB_2684204" "unprognostic (3.27e-2)" "unprognostic (5.21e-3)" "unprognostic (9.70e-2)" "unprognostic (7.25e-2)" "unprognostic (9.71e-2)" "unprognostic (3.78e-2)" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.95e-1)" "unprognostic (1.74e-1)" "unprognostic (1.97e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (1.97e-2)" "unprognostic (2.97e-2)" "unprognostic (6.63e-2)" "unprognostic (1.54e-1)" 23.1 7.1 6.9 16.7 7.8 9.8 16.7 6.9 18.1 20.1 7.6 10.9 8.7 22.6 7.8 9.4 12.5 19.0 14.6 7.1 7.0 5.8 12.8 30.6 30.2 7.7 6.9 21.6 3.5 4.6 4.5 9.3 7.4 4.6 13.6 2.4 6.2 6.3 4.4 6.1 10.3 17.7 7.7 50.1 8.5 3.2 8.5 14.5 31.8 14.3 25.6 15.9 10.7 7.8 0.7 0.0 1.0 0.9 1.0 4.7 0.0 0.2 2.8 0.0 0.4 0.0 0.2 0.1 0.4 0.0 0.2 0.1 0.3 0.0 0.0 103.3 0.5 16.4 0.3 0.0 0.0 0.4 0.6 1.4 0.0 0.0 0.1 0.5 0.1 0.5 60.4 53.4 0.3 0.2 0.1 1.3 0.2 0.1 0.4 0.4 0.0 92.2 0.2 0.2 0.7 0.9 0.0 0.1 0.4 0.2 0.0 1.0 0.0 5.3 1.6 2.0 0.9 3.3 4.6 0.0 2.7 2.6 1.7 0.0 3.5 0.2 0.0 18.6 0.3 0.0 0.1 0.1 47.9 0.0 0.0 0.0 1.4 2.0 14.2 5.2 0.0 2.1 6.9 7.8 6.9 18.1 7.1 7.0 7.7 6.9 7.4 7.7 8.5 7.8 51.2 89.8 54.9 3.9 1.1 13.3 0.8 0.2 2.2 1.2 0.7 1.3 3.2 0.0 5.8 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.5 11.3 60.4 1.2 70.7 8.6 0.2 0.1 25.6 0.5 0.4 3.8 0.5 27.1 1.2 4.7 0.0 7.0 0.6 0.0 73.5 135.0 1.1 13.7 34.5 17.8 8.4 71.4 0.2 0.0 3.0 2.4 0.1 0.0 9.4 2.0 0.5 0.0 0.6 1.5 0.3 6.6 2.5 4.6 0.3 0.3 0.4 13.8 0.0 2.6 5.2 0.1 1.9 CLIC5 DFNB102 ENSG00000112782 "Chloride intracellular channel 5" Q9NZA1 6 45880827-46080348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Hearing, Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel, Voltage-gated channel" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 102.7;skeletal muscle: 289.7;tongue: 98.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 509.6;Cardiomyocytes: 285.7;Distal enterocytes: 164.2;Late spermatids: 93.8;Proximal enterocytes: 126.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 5.1" "Lineage enriched" "Detected in single" 17 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.5;EFO-21: 9.2;HDLM-2: 4.7;REH: 11.9;U-266/70: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074371 Supported "Nuclear speckles,Plasma membrane" NA NA 400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nuclear speckles" "HPA074371: " "unprognostic (4.95e-2)" "unprognostic (1.59e-2)" "unprognostic (8.84e-2)" "unprognostic (5.05e-2)" "unprognostic (2.44e-1)" "unprognostic (6.73e-2)" "unprognostic (3.37e-1)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (6.46e-2)" "unprognostic (5.50e-2)" "unprognostic (3.65e-1)" "unprognostic (6.77e-3)" "unprognostic (1.22e-1)" "unprognostic (1.99e-1)" "unprognostic (8.26e-2)" "unprognostic (1.01e-1)" 18.9 1.5 3.2 4.3 4.4 0.2 6.5 1.5 2.9 19.0 0.5 28.6 20.9 2.1 0.9 2.9 4.5 3.0 102.7 2.1 5.0 54.7 0.3 70.8 1.7 2.1 3.8 0.5 1.1 1.7 3.0 16.5 2.2 2.6 25.8 16.9 2.7 1.4 289.7 1.2 36.6 2.3 1.8 44.5 1.6 1.4 5.5 1.0 7.3 98.3 1.9 2.0 2.6 1.9 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 13.5 0.0 9.2 0.0 0.0 0.3 0.0 0.1 0.0 4.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.1 0.4 1.6 0.0 11.9 0.3 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.4 0.1 0.0 12.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 5.1 0.1 2.0 1.3 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.0 1.0 0.5 3.2 4.4 1.5 2.9 2.1 5.0 2.1 3.8 2.2 1.8 5.5 1.9 59.6 509.6 30.0 4.6 1.4 0.1 0.1 0.0 1.2 0.3 0.5 0.4 285.7 5.7 26.9 14.7 0.0 0.2 0.7 164.2 0.0 1.7 52.9 4.6 0.5 29.8 13.1 0.4 8.6 0.2 0.1 7.9 0.5 5.7 1.3 0.0 0.7 0.0 0.0 0.0 5.4 23.5 0.0 0.0 0.0 93.8 0.9 0.7 0.0 34.7 0.6 53.8 0.0 0.5 2.9 2.9 51.1 0.7 3.4 3.2 126.0 2.9 11.4 1.8 0.0 6.1 4.3 1.0 0.1 0.1 0.1 2.2 5.8 0.1 13.5 4.3 CLTB Lcb ENSG00000175416 "Clathrin light chain B" P09497 5 176392501-176416539 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 1839.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 704.2;MCF7: 641.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003692, HPA036458" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "Plasma membrane, Cytosol" "CAB003692: AB_425372, HPA036458: AB_2675136" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (4.51e-2)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" "unprognostic (3.54e-3)" "unprognostic (1.83e-2)" "unprognostic (1.74e-2)" "unprognostic (1.93e-1)" "unprognostic (7.42e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (7.89e-5)" "unprognostic (3.55e-1)" "unprognostic (7.50e-2)" "unprognostic (8.59e-2)" "unprognostic (1.60e-2)" 102.9 133.6 125.8 50.1 125.1 40.6 82.9 117.8 176.7 180.4 125.3 133.9 92.3 85.9 23.2 473.7 82.4 34.1 320.8 130.8 129.6 90.4 82.5 96.5 32.9 136.9 122.8 107.2 68.2 70.1 112.8 57.5 138.1 88.1 45.5 37.9 128.6 44.4 322.5 453.1 99.7 41.2 114.5 68.7 123.3 38.9 127.9 43.7 69.5 120.8 58.5 106.2 300.8 133.6 229.1 107.6 29.9 128.2 65.7 49.2 244.4 286.3 110.9 178.6 127.0 140.3 103.9 49.6 165.0 130.2 71.8 213.3 51.4 704.2 69.7 341.7 95.3 33.6 163.3 87.7 102.9 53.2 85.6 52.6 241.5 98.1 114.7 36.0 84.7 39.2 65.2 123.4 100.3 641.9 84.5 81.1 24.4 189.5 158.2 91.3 52.9 165.2 95.6 92.0 127.7 43.7 136.6 148.0 103.6 34.7 61.4 101.9 185.2 64.0 96.3 117.5 165.1 96.5 73.3 68.5 51.4 112.7 74.4 6.6 19.7 61.7 13.6 15.8 7.0 5.9 11.9 13.2 20.0 10.1 10.0 10.0 36.6 15.0 20.8 16.1 24.9 8.1 125.8 125.1 117.8 176.7 130.8 129.6 136.9 122.8 138.1 114.5 127.9 133.6 113.7 57.7 19.8 8.5 54.7 634.0 238.7 155.7 180.4 310.5 105.5 124.6 208.5 72.9 93.4 82.8 64.6 141.1 82.3 794.5 135.0 324.7 9.5 58.4 72.7 102.2 151.8 43.6 25.4 453.1 586.9 136.7 193.2 85.2 48.2 40.8 70.3 96.3 111.9 336.5 24.1 348.5 114.0 80.7 226.1 13.7 122.1 88.4 220.5 6.5 85.7 136.1 107.1 8.0 15.2 1839.9 786.9 129.8 76.4 391.4 545.7 269.7 49.6 64.3 78.9 79.6 161.4 15.9 29.1 415.6 803.0 386.5 81.3 151.2 289.7 436.0 CNNM4 "ACDP4, KIAA1592" ENSG00000158158 "Cyclin and CBS domain divalent metal cation transport mediator 4" Q6P4Q7 2 96760902-96811874 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Biomineralization, Ion transport, Sensory transduction, Transport, Vision" "Amelogenesis imperfecta, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 38.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 112.6;Distal enterocytes: 103.4;Rod photoreceptor cells: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "SK-BR-3: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017732 Enhanced Uncertain "Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "Plasma membrane" "HPA017732: AB_1847395" "unprognostic (1.98e-3)" "unprognostic (8.95e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (3.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.54e-3)" "unprognostic (3.36e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.75e-4)" "unprognostic (4.75e-3)" "unprognostic (3.72e-1)" "unprognostic (8.14e-2)" "unprognostic (3.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" 2.8 3.6 5.0 6.1 6.8 4.9 7.0 11.2 5.4 5.8 2.8 32.4 6.2 4.0 4.7 7.1 10.4 4.4 12.5 4.9 4.4 6.8 4.4 8.0 4.6 4.1 4.5 5.1 7.4 6.3 9.1 5.8 4.2 5.7 34.3 38.8 6.8 5.1 24.8 7.2 11.3 4.7 3.5 5.3 12.8 7.9 4.5 3.5 9.5 13.1 4.9 5.5 6.4 5.7 11.1 7.2 5.7 10.5 5.8 3.9 15.6 4.8 6.8 6.9 9.3 13.2 11.8 8.1 13.5 5.0 9.5 14.1 14.9 8.1 6.3 16.3 11.7 6.4 4.8 7.2 8.1 3.1 6.2 3.8 10.0 11.0 6.6 4.6 3.8 8.0 3.3 22.3 3.6 15.7 6.6 4.5 7.5 20.5 9.8 9.7 2.6 9.3 6.9 8.6 26.7 8.0 9.1 45.7 6.8 15.9 22.3 5.3 3.4 4.0 8.9 8.8 5.4 7.7 6.6 4.0 5.9 6.1 7.2 1.2 0.4 0.1 0.8 0.4 0.2 0.9 0.4 0.4 0.6 0.5 0.2 0.5 0.2 0.2 0.7 0.4 0.2 0.3 5.0 6.8 11.2 5.4 4.9 4.4 4.1 4.5 4.2 3.5 4.5 5.7 4.5 38.5 7.7 12.4 6.4 5.7 4.9 4.0 4.6 43.1 14.7 11.2 14.1 4.3 11.6 7.3 112.6 5.4 6.1 103.4 0.0 3.2 4.9 14.3 4.4 4.0 10.1 0.8 9.8 4.2 1.7 3.2 12.2 16.1 1.3 5.9 2.2 3.3 3.3 33.7 8.3 26.4 6.1 5.4 4.8 1.6 0.9 5.9 0.0 8.4 2.3 8.3 2.1 11.1 14.6 5.2 21.3 1.2 4.5 4.1 22.3 1.2 10.6 51.5 0.0 4.6 4.3 4.6 2.5 7.3 4.1 6.7 5.4 6.7 26.5 6.1 CNP ENSG00000173786 "2',3'-cyclic nucleotide 3' phosphodiesterase" P09543 17 41966763-41977740 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "brain: 1395.7" "Cell type enriched" "Detected in all" 4 "Oligodendrocytes: 555.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 149.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Region enriched" "Detected in all" 4 "white matter: 1789.4" "Low region specificity" "Detected in all" "CAB002672, HPA023266, HPA023278, HPA023280, HPA023338" Enhanced Supported Supported "Plasma membrane" NA NA 46000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB002672: , HPA023266: AB_1847058, HPA023278: AB_1847060, HPA023280: AB_1847061, HPA023338: AB_1847062" "unprognostic (2.17e-1)" "unprognostic (4.48e-2)" "unprognostic (3.85e-3)" "unprognostic (1.41e-1)" "unprognostic (3.09e-1)" "unprognostic (9.71e-2)" "unprognostic (2.58e-3)" "unprognostic (2.08e-1)" "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.87e-1)" "unprognostic (2.99e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (8.86e-2)" "unprognostic (1.10e-3)" 34.4 33.5 493.1 31.2 889.6 23.4 29.6 715.5 681.5 41.7 193.5 56.9 21.4 33.5 36.7 63.4 28.9 32.6 25.3 505.1 577.0 58.1 44.8 21.7 35.7 839.4 761.8 32.2 27.8 23.7 28.1 23.5 793.8 41.5 18.4 20.5 47.2 37.2 26.3 34.3 31.4 30.3 644.6 25.8 29.8 16.7 791.1 31.2 24.7 22.2 35.1 37.3 40.5 1395.7 56.9 92.4 85.8 106.6 71.7 67.2 38.5 70.1 102.5 171.1 191.5 73.0 49.6 59.0 54.3 88.5 88.1 95.0 58.3 44.6 59.0 59.7 76.8 56.7 59.3 127.7 76.9 56.7 49.6 111.0 31.5 94.1 22.8 61.9 79.4 58.0 42.4 46.4 60.6 35.1 148.5 50.9 20.7 29.8 66.5 91.4 126.7 58.7 45.7 55.7 50.9 69.5 85.7 127.0 155.5 41.6 57.2 82.3 80.2 66.6 73.7 92.3 81.9 53.4 66.6 47.5 66.1 42.9 266.4 18.7 38.2 23.4 21.5 40.7 17.2 28.0 18.8 17.4 33.8 19.2 16.6 19.6 7.7 23.5 34.0 149.4 22.4 33.0 493.1 889.6 715.5 681.5 505.1 577.0 839.4 761.8 793.8 644.6 791.1 1395.7 26.6 16.0 12.7 14.4 19.0 16.7 17.5 10.4 16.5 22.0 29.5 24.0 13.0 20.0 19.5 35.0 6.2 30.6 53.2 39.9 125.2 46.3 1.3 19.1 27.1 24.8 19.7 25.2 6.8 41.7 50.2 27.7 17.9 21.3 9.5 20.2 20.3 32.3 39.8 50.5 9.5 16.2 18.3 17.0 14.5 4.0 38.8 20.3 55.2 14.0 25.0 84.7 23.7 45.2 555.6 35.5 19.0 36.1 27.8 21.7 19.0 80.5 12.8 25.4 32.9 36.6 29.4 5.1 16.0 30.9 18.9 13.0 16.9 33.3 20.6 17.4 CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166359 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.0;brain: 25.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 44.6;Inhibitory neurons: 200.3;Sertoli cells: 98.6" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 81.4;HSkMC: 53.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments" "HPA042256: AB_2677917, HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" 23.0 5.4 10.4 3.5 25.1 0.7 16.9 7.5 22.8 5.7 0.0 12.3 1.1 6.9 2.6 2.4 11.2 2.0 1.0 19.5 11.8 0.9 0.1 4.0 4.4 9.9 1.1 3.8 1.5 0.5 20.7 3.1 0.5 2.9 2.9 1.5 2.6 2.1 2.4 3.8 10.5 3.6 0.0 1.7 4.3 1.2 18.0 1.3 5.1 1.2 6.6 4.1 5.1 3.0 0.0 0.1 3.8 0.0 81.4 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.2 1.9 2.9 0.0 5.3 0.0 0.0 53.8 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.5 0.0 6.8 0.0 1.7 0.1 0.0 0.0 0.0 0.3 0.0 1.4 4.9 0.0 0.0 0.1 0.0 0.0 1.6 7.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 25.1 7.5 22.8 19.5 11.8 9.9 1.1 0.5 0.0 18.0 3.0 3.4 0.0 10.4 3.6 7.1 0.6 0.5 0.0 0.0 1.7 0.1 0.4 0.9 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.4 3.8 0.0 0.0 44.6 0.0 0.0 0.9 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 200.3 0.0 0.0 0.3 0.8 0.0 1.5 0.2 0.0 5.6 0.0 0.0 0.0 9.0 3.2 0.0 0.1 0.4 4.2 0.0 0.0 0.0 0.0 0.2 98.6 6.4 12.4 0.0 0.5 0.2 0.1 0.1 0.5 0.0 0.0 0.8 COG3 SEC34 ENSG00000136152 "Component of oligomeric golgi complex 3" Q96JB2 13 45464898-45536701 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040353, HPA054470" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Plasma membrane" "Nucleoplasm, Cytosol" "HPA040353: AB_10794027, HPA054470: AB_2732585" "unprognostic (1.75e-1)" "unprognostic (3.03e-3)" "unprognostic (1.75e-1)" "unprognostic (4.04e-3)" "unprognostic (9.69e-2)" "unprognostic (2.86e-2)" "unprognostic (2.18e-2)" "unprognostic (4.46e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (9.53e-4)" "unprognostic (5.82e-2)" "unprognostic (1.21e-2)" "unprognostic (4.49e-2)" "unprognostic (7.06e-3)" "unprognostic (1.13e-1)" "unprognostic (8.25e-2)" "unprognostic (1.71e-1)" 11.2 15.0 7.5 9.3 7.7 11.8 15.6 10.5 9.3 15.2 10.5 16.2 12.6 13.0 16.8 12.4 12.2 9.5 11.8 7.4 7.2 12.3 29.5 10.4 10.7 7.0 7.0 15.1 20.8 12.3 14.9 13.0 7.0 18.7 18.9 10.0 18.0 12.4 11.4 13.2 13.2 12.1 6.8 12.4 14.7 9.7 7.5 12.2 17.0 9.7 10.9 12.7 13.1 9.4 8.3 7.4 13.9 12.6 17.9 20.4 13.2 13.5 19.1 15.4 12.8 10.8 14.9 11.3 5.9 16.2 11.4 17.7 11.6 13.7 23.3 8.9 9.3 12.7 9.2 19.2 22.1 18.8 11.7 15.4 20.3 10.3 36.1 18.6 15.2 11.0 8.3 6.8 18.7 12.9 10.5 17.6 11.4 41.5 8.7 12.1 8.1 10.6 14.4 13.4 6.9 12.5 8.7 17.1 18.2 13.1 11.7 19.3 14.4 7.4 5.7 13.9 8.7 9.4 5.4 11.7 14.2 9.4 13.5 3.5 1.9 3.6 3.4 2.2 3.6 2.2 2.6 2.9 1.4 2.3 2.9 2.7 1.7 2.5 1.3 3.4 3.0 1.7 7.5 7.7 10.5 9.3 7.4 7.2 7.0 7.0 7.0 6.8 7.5 9.4 15.8 9.6 31.4 23.2 18.9 15.8 15.2 13.1 14.2 9.7 22.0 17.9 19.7 24.3 19.8 12.9 14.6 14.2 35.5 32.5 15.6 11.6 24.1 15.0 20.1 16.7 22.2 11.4 39.3 37.9 18.8 14.3 26.0 30.8 17.1 22.4 18.9 72.8 10.8 10.1 34.7 54.5 6.1 20.9 9.0 9.0 14.0 13.3 10.6 22.5 13.2 7.6 15.5 34.2 36.9 22.7 32.8 13.5 31.3 26.6 29.4 17.3 11.7 11.2 6.6 12.8 11.7 12.7 8.9 17.7 16.1 32.8 21.2 21.7 24.4 37.3 COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 585.7;Basal respiratory cells: 136.0;Basal squamous epithelial cells: 299.9;Distal enterocytes: 211.5;Proximal enterocytes: 108.5;Suprabasal keratinocytes: 139.4" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 204.3;HaCaT: 463.8;HBEC3-KT: 745.8;hTCEpi: 914.1;hTERT-HME1: 783.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" 1.5 0.4 0.8 6.6 1.1 12.2 37.3 1.0 1.4 50.1 0.6 37.4 10.7 0.6 6.6 116.6 1.1 0.3 0.5 0.5 0.6 0.3 0.3 0.9 0.1 0.6 0.7 0.2 0.4 0.0 1.2 35.4 0.6 17.9 27.3 0.0 82.2 9.6 0.5 580.3 37.2 1.0 0.5 2.3 19.8 25.4 0.6 42.7 5.1 0.0 19.8 9.9 102.0 0.8 26.3 0.4 1.5 0.2 0.1 0.0 80.6 0.5 0.3 0.1 0.2 0.3 204.3 0.0 5.1 0.3 3.9 463.8 0.7 745.8 0.7 0.0 0.7 0.0 0.3 0.2 0.1 0.0 0.4 0.7 914.1 0.5 783.7 0.2 3.5 0.1 0.1 0.9 0.0 0.0 0.0 0.3 1.7 5.1 2.6 0.0 0.0 0.3 35.9 26.4 0.2 0.3 0.0 0.2 0.9 4.0 0.2 0.0 1.5 0.5 5.0 0.3 5.5 0.1 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 1.0 1.4 0.5 0.6 0.6 0.7 0.6 0.5 0.6 0.8 1.0 0.0 1.1 0.7 0.3 585.7 17.7 136.0 299.9 0.6 1.7 85.5 1.1 0.0 16.5 0.0 0.0 10.2 0.3 211.5 0.0 0.8 14.2 23.7 2.3 3.7 2.4 0.0 0.1 0.9 18.9 2.4 23.0 8.1 0.0 0.1 0.0 0.0 1.3 0.0 0.2 5.7 6.1 0.0 28.9 3.6 0.3 0.7 33.8 0.0 0.0 0.4 0.0 0.0 0.4 78.8 35.7 0.7 1.4 16.6 108.5 0.1 5.9 0.4 0.0 0.4 3.0 22.7 1.5 31.9 139.4 5.6 1.3 0.1 21.6 10.7 CORO1B coronin-2 ENSG00000172725 "Coronin 1B" Q9BR76 11 67435510-67443821 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 301.4;Paneth cells: 324.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 221.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017616, HPA040113, HPA070456" Enhanced Supported "Plasma membrane,Cytosol" NA NA 960000 "Cluster 51: Monocytes - Innate immune response" "Cluster 4: Stomach - Digestion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB017616: AB_2087018, HPA040113: AB_2676850, HPA070456: AB_2686268" "unprognostic (1.94e-1)" "unprognostic (2.40e-1)" "unprognostic (3.21e-1)" "prognostic favorable (1.65e-4)" "unprognostic (1.02e-1)" "unprognostic (8.23e-3)" "unprognostic (1.49e-3)" "unprognostic (7.22e-2)" "unprognostic (1.86e-1)" "unprognostic (4.86e-2)" "unprognostic (1.48e-1)" "unprognostic (3.88e-2)" "unprognostic (8.58e-3)" "unprognostic (1.85e-1)" "unprognostic (1.04e-1)" "unprognostic (1.21e-2)" "unprognostic (6.64e-3)" 54.4 56.4 20.2 29.7 23.8 20.3 53.4 23.4 27.0 55.7 21.1 70.2 62.9 72.8 14.6 80.2 54.2 44.1 26.1 19.4 22.7 48.2 47.2 53.7 41.9 28.0 23.6 42.7 52.5 24.6 35.1 31.2 25.1 71.0 34.5 6.6 73.2 39.6 13.0 42.4 62.3 36.7 24.2 66.0 77.1 13.9 25.1 21.1 55.8 9.9 18.4 58.3 53.5 26.3 80.9 81.4 37.5 76.0 94.1 81.3 56.6 58.5 118.0 94.2 70.8 134.1 116.0 6.4 111.3 80.8 95.8 67.9 41.9 74.9 16.8 19.4 40.7 54.9 47.3 57.9 148.1 2.3 120.8 110.6 66.3 80.1 37.2 59.7 120.7 49.4 42.7 9.2 54.2 238.4 14.4 11.2 47.7 198.2 73.4 11.2 41.0 14.9 62.6 104.3 40.7 50.8 52.4 139.6 181.6 26.0 178.5 63.0 92.2 63.4 47.4 87.4 35.2 1.6 3.3 14.6 103.4 8.2 66.4 57.3 102.8 8.0 10.9 212.9 8.3 20.0 37.6 14.6 79.0 11.0 21.2 11.4 47.8 11.9 221.8 60.8 55.2 57.8 20.2 23.8 23.4 27.0 19.4 22.7 28.0 23.6 25.1 24.2 25.1 26.3 58.7 3.2 2.2 4.6 53.4 27.9 60.1 90.8 40.9 13.0 53.8 39.0 1.6 50.1 66.4 47.8 8.4 87.8 39.2 301.4 60.7 111.4 8.9 43.6 32.9 52.0 99.0 19.8 1.8 105.0 229.8 35.8 111.1 64.8 28.0 46.7 47.8 22.4 251.8 15.2 2.4 188.6 81.4 138.6 66.4 5.0 39.4 96.3 71.2 10.3 195.3 30.0 41.2 4.5 6.8 136.9 324.9 34.6 64.3 55.6 263.5 84.0 41.2 14.6 52.6 22.1 55.1 8.1 6.6 47.6 31.0 150.5 100.3 54.8 128.0 74.5 CPPED1 "CSTP1, FLJ11151" ENSG00000103381 "Calcineurin like phosphoesterase domain containing 1" Q9BRF8 16 12659799-12803887 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 105.2;monocytes: 127.4;Syncytiotrophoblasts: 131.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 674.2" "Group enriched" "Detected in all" 28 "dendritic cells: 168.5;granulocytes: 674.2;monocytes: 320.8" "Cell line enhanced" "Detected in many" "Hep G2: 144.2;HMC-1: 129.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040938, HPA041970" Uncertain Supported "Plasma membrane,Cytosol" No No 470000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Plasma membrane" "HPA040938: AB_10673443, HPA041970: AB_2677774" "prognostic unfavorable (9.72e-4)" "unprognostic (1.70e-1)" "unprognostic (2.04e-3)" "unprognostic (1.05e-2)" "unprognostic (1.13e-3)" "unprognostic (3.86e-2)" "unprognostic (1.35e-1)" "unprognostic (8.67e-2)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (6.26e-2)" "unprognostic (3.64e-1)" "prognostic favorable (1.62e-9)" "unprognostic (5.05e-2)" "unprognostic (1.25e-1)" "unprognostic (2.48e-3)" "unprognostic (2.40e-2)" 12.5 9.4 9.1 19.3 14.1 14.0 8.2 13.0 11.4 11.0 7.3 13.3 21.3 7.9 5.1 25.2 7.1 11.2 10.1 8.3 13.3 33.7 34.4 13.7 11.7 14.0 13.1 7.6 4.8 3.9 4.1 18.5 14.4 11.1 14.8 3.7 13.1 8.6 8.2 6.5 21.4 12.9 11.3 29.8 8.7 15.5 12.2 9.2 13.2 9.6 16.6 11.5 8.8 17.3 5.0 29.7 3.3 7.7 12.0 25.3 0.5 54.1 14.5 28.4 23.1 14.5 15.2 7.3 54.6 39.6 12.5 0.4 0.0 13.5 29.3 17.0 8.2 62.5 4.2 144.2 7.4 0.1 129.9 25.4 3.0 2.5 20.2 0.1 43.1 9.9 22.1 4.3 70.4 6.3 5.6 29.1 8.7 2.4 4.2 11.9 18.8 15.6 43.0 9.4 15.3 10.0 0.2 48.5 20.0 15.3 10.5 13.7 65.0 40.6 8.5 0.2 0.1 0.1 1.0 11.6 9.1 31.7 8.8 57.1 224.0 146.1 9.1 320.0 7.8 10.8 7.6 10.0 168.5 8.4 2.4 5.7 674.2 13.5 320.8 41.1 13.8 129.7 9.1 14.1 13.0 11.4 8.3 13.3 14.0 13.1 14.4 11.3 12.2 17.3 12.3 9.6 16.7 8.1 8.7 4.6 3.4 4.9 4.6 3.3 4.7 4.7 10.7 10.0 11.4 14.7 8.4 105.2 18.5 9.2 60.7 43.1 3.6 5.3 13.5 16.7 6.0 31.7 13.1 12.8 15.6 12.6 4.1 9.4 54.4 8.1 7.5 45.8 47.1 10.1 10.2 9.3 6.1 80.3 30.7 4.1 15.5 59.0 7.2 30.0 127.4 13.5 8.2 21.1 70.9 31.9 18.3 24.0 4.4 3.2 40.6 66.0 13.4 6.1 26.3 17.6 11.9 2.5 9.9 14.8 4.5 131.9 8.3 13.6 15.4 1.7 CRHR2 "CRF-RB, CRF2, HM-CRF" ENSG00000106113 "Corticotropin releasing hormone receptor 2" Q13324 7 30651942-30700129 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.0;choroid plexus: 21.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 3.0;Excitatory neurons: 8.2;Horizontal cells: 13.5;Inhibitory neurons: 4.9;Smooth muscle cells: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Low region specificity" "Detected in many" HPA073345 Supported "Plasma membrane" "Secreted - unknown location" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA073345: " "unprognostic (7.14e-2)" "unprognostic (4.20e-1)" "unprognostic (1.68e-1)" "unprognostic (1.24e-3)" "unprognostic (5.69e-2)" "unprognostic (8.58e-2)" "unprognostic (6.00e-2)" "unprognostic (1.86e-4)" "unprognostic (2.01e-1)" "unprognostic (3.07e-1)" "unprognostic (5.90e-4)" "unprognostic (4.02e-2)" "unprognostic (8.29e-4)" "unprognostic (3.73e-3)" "unprognostic (2.84e-3)" "unprognostic (1.81e-1)" "unprognostic (3.84e-1)" 0.6 0.0 1.5 0.0 1.0 0.0 0.6 0.4 6.0 0.3 21.7 0.2 0.3 0.3 0.0 0.2 0.5 0.1 2.1 2.3 1.0 0.8 0.0 0.1 0.0 1.4 1.0 0.4 1.7 0.1 4.2 0.0 0.4 0.2 0.1 2.5 0.3 1.3 1.2 0.2 0.3 0.1 0.4 0.0 0.2 0.8 2.8 0.0 0.7 2.2 0.0 0.3 0.2 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.0 0.4 6.0 2.3 1.0 1.4 1.0 0.4 0.4 2.8 2.4 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 4.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CSF1 "M-CSF, MCSF, MGC31930" ENSG00000184371 "Colony stimulating factor 1" P09603 1 109910242-109930992 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 58.9;granulocytes: 113.5;Hepatic stellate cells: 53.2;Sertoli cells: 59.2;Skeletal myocytes: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 13.2;eosinophil: 22.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 22.3" "Cell line enhanced" "Detected in many" "ASC diff: 220.0;BJ hTERT+: 149.5;GAMG: 142.1;HHSteC: 338.7;HSkMC: 216.4;hTERT-RPE1: 153.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076624 Supported "Nuclear bodies,Plasma membrane" "Secreted to blood" NA NA 270000 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies" "HPA076624: AB_2686810" "unprognostic (2.35e-3)" "unprognostic (2.14e-1)" "unprognostic (7.36e-2)" "unprognostic (4.19e-1)" "unprognostic (3.60e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (4.25e-5)" "unprognostic (1.04e-1)" "unprognostic (1.75e-2)" "unprognostic (2.18e-1)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "prognostic unfavorable (1.00e-11)" "unprognostic (2.03e-1)" "unprognostic (1.88e-2)" "unprognostic (4.01e-1)" "unprognostic (3.16e-2)" 67.4 37.5 27.5 24.5 32.9 18.4 46.4 36.9 25.8 25.0 32.9 26.8 13.3 21.1 5.2 15.6 28.5 31.9 29.0 24.5 30.9 17.3 16.4 47.6 28.2 42.3 32.6 22.1 17.5 10.5 8.7 41.2 36.1 21.4 16.2 1.5 18.9 16.6 11.4 19.4 26.7 17.6 36.0 48.0 22.0 3.7 32.2 13.5 22.2 11.3 12.2 42.0 29.6 46.5 9.3 29.3 14.7 5.7 220.0 138.3 5.7 36.0 149.5 25.9 23.9 1.3 4.5 0.2 47.0 80.1 142.1 6.8 5.7 11.0 9.4 99.5 5.3 10.9 17.3 10.3 338.7 0.0 13.7 216.4 3.2 57.5 33.0 153.1 5.4 2.8 2.9 5.5 31.2 0.5 0.3 1.8 5.3 2.4 3.1 1.0 8.4 0.9 10.9 7.9 0.5 1.6 9.7 2.6 12.6 16.7 2.3 1.0 19.2 27.8 10.5 123.7 22.1 2.8 1.1 0.3 70.7 0.1 106.6 13.2 0.0 22.3 0.3 0.0 0.6 0.0 0.9 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.3 0.2 27.5 32.9 36.9 25.8 24.5 30.9 42.3 32.6 36.1 36.0 32.2 46.5 30.6 9.6 35.5 11.8 2.3 7.4 5.1 7.9 13.1 0.3 10.0 9.3 3.2 14.3 5.3 3.7 0.0 0.8 2.0 0.6 0.0 40.4 0.4 20.6 9.3 21.6 7.8 11.1 0.3 2.3 0.5 58.9 4.6 24.8 113.5 0.3 53.2 3.0 9.2 0.0 1.0 0.8 0.0 3.5 13.1 0.3 25.1 8.2 10.6 28.1 1.6 1.8 0.0 3.0 17.5 9.3 1.6 8.6 1.9 8.0 1.2 0.9 1.1 0.2 59.2 94.4 37.1 0.6 0.7 5.6 5.5 0.8 20.9 0.7 1.0 2.6 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.3;placenta: 103.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 103.2;Hofbauer cells: 340.4;Kupffer cells: 291.2;Langerhans cells: 73.4;Macrophages: 196.3;Microglial cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.6;non-classical monocyte: 646.9" "Lineage enriched" "Detected in many" 5 "monocytes: 646.9" "Group enriched" "Detected in some" 4 "BEWO: 123.0;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1600000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 51.3 31.0 19.6 75.1 17.1 5.6 19.3 20.2 21.4 21.6 19.3 21.9 24.3 12.1 5.8 21.0 17.2 40.6 16.6 19.8 33.8 7.1 27.5 36.6 54.4 41.4 35.5 12.7 9.9 11.8 5.7 103.3 40.1 9.1 21.5 1.5 10.1 20.8 3.2 13.4 37.3 41.9 36.6 113.3 21.0 7.0 40.6 14.3 6.0 11.8 21.7 42.6 3.8 67.6 4.5 0.2 0.0 0.0 1.9 0.4 123.0 0.2 0.2 0.0 0.0 3.8 0.0 5.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 1.1 3.0 0.0 6.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.1 0.1 0.0 0.0 0.0 1.9 0.6 0.0 0.0 0.2 0.2 0.0 47.8 0.0 1.9 0.0 20.7 0.0 0.8 0.2 0.1 3.3 0.0 0.3 0.1 6.6 2.6 0.0 3.0 138.4 4.0 0.6 444.6 0.6 0.3 0.2 0.4 139.0 0.2 0.3 0.2 21.6 0.2 646.9 11.1 0.5 132.7 19.6 17.1 20.2 21.4 19.8 33.8 41.4 35.5 40.1 36.6 40.6 67.6 2.0 0.0 3.8 0.0 4.3 2.8 0.0 0.0 1.2 0.0 0.5 2.3 3.1 4.3 0.0 0.0 0.0 6.2 2.8 0.0 0.0 0.0 4.8 0.0 0.1 10.5 0.0 2.5 0.4 0.0 103.2 2.2 1.5 0.2 2.5 8.3 2.9 1.5 340.4 0.0 0.5 0.3 0.0 291.2 73.4 5.4 1.8 196.3 3.6 134.9 39.4 0.0 1.0 1.5 0.3 0.1 1.7 0.0 1.0 0.0 0.0 0.1 0.7 0.5 13.1 1.2 2.0 2.2 0.2 0.4 1.3 26.4 1.3 2.2 0.2 0.0 CTTN EMS1 ENSG00000085733 Cortactin Q14247 11 70398404-70436584 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.2;neutrophil: 2.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.1" "Cell line enhanced" "Detected in many" "A-431: 450.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011235, HPA057242" Supported Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" NA NA 11000000 "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "Golgi apparatus, Vesicles" "CAB011235: , HPA057242: AB_2683379" "unprognostic (6.34e-2)" "unprognostic (2.65e-2)" "unprognostic (2.05e-1)" "unprognostic (3.13e-2)" "unprognostic (5.81e-2)" "prognostic unfavorable (2.19e-6)" "prognostic unfavorable (4.45e-4)" "unprognostic (6.10e-2)" "unprognostic (2.39e-1)" "unprognostic (1.10e-1)" "unprognostic (1.25e-3)" "unprognostic (1.20e-1)" "unprognostic (1.50e-2)" "unprognostic (6.97e-2)" "unprognostic (2.79e-1)" "unprognostic (3.72e-3)" "unprognostic (1.94e-1)" 91.7 142.5 28.3 15.6 30.0 4.9 82.9 29.7 32.3 112.3 28.5 84.9 28.4 117.8 18.7 131.6 85.0 35.1 106.9 27.7 28.2 109.6 66.9 74.8 9.0 33.2 30.8 112.9 79.5 18.1 94.1 23.9 30.9 101.6 23.8 8.4 92.9 27.0 65.7 104.4 70.9 31.8 29.5 53.3 92.2 62.0 30.3 8.7 89.5 14.5 12.7 88.1 101.2 32.5 450.2 97.2 32.0 37.2 53.2 81.9 52.5 93.8 92.5 80.7 63.4 129.5 110.3 17.5 90.6 121.1 86.3 97.3 38.6 98.7 58.7 35.5 39.1 1.7 73.6 61.1 113.9 0.4 22.6 116.6 68.0 89.4 50.2 84.4 68.8 0.5 51.3 3.3 80.9 122.9 0.9 6.4 35.0 163.4 58.6 0.2 39.3 14.3 90.5 143.7 26.3 44.9 68.3 93.2 158.0 57.2 75.8 1.9 86.8 70.8 45.3 111.2 63.6 7.4 5.2 1.0 141.1 0.4 98.9 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 2.1 0.0 0.1 0.4 0.0 6.8 28.3 30.0 29.7 32.3 27.7 28.2 33.2 30.8 30.9 29.5 30.3 32.5 95.3 44.8 51.8 61.7 4.0 151.9 102.8 85.8 46.1 39.4 81.0 57.9 64.1 80.1 95.4 134.3 18.8 83.8 1.6 224.4 64.6 146.5 12.4 86.4 84.8 89.9 74.4 18.9 93.4 221.5 95.6 89.1 76.0 116.1 6.3 117.7 78.9 44.1 10.4 38.7 65.4 123.8 57.0 8.9 34.1 26.1 103.2 38.6 122.7 28.1 5.9 42.5 0.0 40.2 145.8 260.6 177.8 98.9 3.1 153.5 108.4 164.3 89.4 32.5 59.2 61.0 87.5 32.0 47.0 76.7 174.9 106.3 5.4 91.4 111.9 258.1 CX3CL1 "ABCD-3, C3Xkine, CXC3, CXC3C, NTN, SCYD1" ENSG00000006210 "C-X3-C motif chemokine ligand 1" P78423 16 57372477-57385044 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Chemotaxis, Host-virus interaction, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 104.8" "Cell type enhanced" "Detected in many" "Adipocytes: 115.4;Basal prostatic cells: 50.8;Basal respiratory cells: 51.8;Breast glandular cells: 62.3;Breast myoepithelial cells: 51.1;Club cells: 54.8;Endothelial cells: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "EFO-21: 30.1;HDLM-2: 86.0;Hep G2: 63.8;RPTEC TERT1: 36.5;SK-BR-3: 21.5" "Low region specificity" "Detected in all" "CAB026192, HPA040361" Approved Supported "Plasma membrane" "Secreted to blood" NA NA 1870000 370000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB026192: , HPA040361: AB_10796453" "unprognostic (6.89e-3)" "prognostic favorable (9.46e-4)" "unprognostic (1.52e-2)" "unprognostic (3.20e-2)" "unprognostic (1.73e-1)" "unprognostic (1.82e-1)" "unprognostic (7.12e-2)" "unprognostic (2.08e-3)" "unprognostic (4.49e-2)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-2)" "prognostic favorable (8.52e-7)" "unprognostic (5.19e-2)" "unprognostic (2.72e-1)" "unprognostic (1.11e-2)" "unprognostic (9.33e-2)" 68.3 4.8 36.4 5.7 39.5 0.1 104.8 11.9 44.8 17.6 19.8 14.3 5.1 13.7 8.7 14.4 18.2 21.0 43.0 46.9 26.4 41.9 14.9 98.8 8.5 25.1 24.8 8.3 13.1 7.1 11.2 3.9 23.6 42.2 5.4 4.3 70.8 45.3 15.0 27.3 12.8 10.6 21.8 1.4 14.5 5.7 30.5 5.2 29.7 19.2 6.2 33.0 17.3 31.2 0.0 0.8 8.0 6.8 0.3 0.1 2.0 0.1 0.0 0.0 0.1 3.1 0.0 0.0 30.1 0.1 4.3 0.3 0.0 0.1 0.0 86.0 0.4 0.0 0.0 63.8 0.9 0.0 0.1 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 2.8 0.1 0.0 0.1 1.1 0.2 36.5 0.2 0.2 7.1 0.0 21.5 1.9 5.1 0.1 0.2 0.1 0.3 4.7 0.2 2.1 0.1 0.0 0.0 0.1 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 36.4 39.5 11.9 44.8 46.9 26.4 25.1 24.8 23.6 21.8 30.5 31.2 115.4 3.2 4.6 3.3 1.2 4.5 50.8 51.8 31.9 9.8 62.3 51.1 8.3 21.5 54.8 3.7 4.2 0.0 0.8 0.5 0.0 35.1 0.4 12.9 3.3 50.7 1.8 0.0 28.1 1.8 0.1 9.0 0.5 27.3 1.3 0.2 6.1 11.7 0.0 5.0 20.5 0.3 20.3 0.8 4.7 0.5 4.7 0.6 0.0 16.9 0.6 0.8 0.0 13.0 3.2 4.3 0.6 27.8 0.0 29.7 0.2 11.8 28.8 2.2 13.1 2.8 15.7 0.1 0.1 10.3 2.6 0.3 0.8 0.3 1.0 32.6 CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 221.2;Fibroblasts: 243.4;Leydig cells: 202.0;Peritubular cells: 221.5;Proximal enterocytes: 689.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.7;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "ASC diff: 1064.0;ASC TERT1: 453.8;BJ hTERT+: 408.2;HSkMC: 327.3;hTERT-RPE1: 276.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA014757: AB_1847374" "unprognostic (1.35e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.44e-3)" "unprognostic (8.90e-3)" "unprognostic (3.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-3)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-2)" 166.7 97.5 32.6 24.4 38.8 18.3 148.7 33.9 34.1 140.0 32.6 68.7 197.7 100.2 49.7 70.6 88.2 153.7 128.6 28.2 45.9 32.0 21.7 129.9 33.8 45.2 38.7 180.9 21.6 12.0 26.1 38.1 40.5 70.6 39.0 22.2 63.7 76.7 23.3 85.0 233.4 87.9 35.6 30.6 53.3 23.8 35.9 27.9 231.0 82.8 30.1 84.3 90.4 43.0 24.8 18.1 10.1 19.2 1064.0 453.8 1.3 88.3 408.2 45.0 56.4 1.1 33.8 0.0 14.8 214.2 46.2 12.2 8.4 7.2 53.2 18.9 2.2 20.7 26.1 0.4 222.7 22.0 1.9 327.3 68.8 70.5 13.7 276.3 29.6 12.4 7.0 0.2 128.3 0.0 7.1 20.4 5.1 0.0 4.6 2.5 125.3 1.5 7.0 1.4 1.3 4.7 104.2 0.2 56.5 3.6 35.8 13.5 59.5 101.0 14.4 96.1 38.3 0.3 0.4 0.2 49.5 18.3 55.6 0.0 17.4 0.8 1.6 17.7 0.3 0.0 0.3 0.2 16.8 0.0 0.0 0.0 9.8 3.6 13.7 0.7 0.0 7.5 32.6 38.8 33.9 34.1 28.2 45.9 45.2 38.7 40.5 35.6 35.9 43.0 37.6 221.2 109.0 45.1 0.9 121.2 47.3 20.3 38.7 0.0 54.7 48.0 18.4 37.1 34.7 25.8 0.0 1.9 3.4 16.1 0.0 1.0 1.5 4.2 35.6 33.9 0.0 85.0 0.9 6.4 2.3 243.4 13.3 8.3 2.5 1.6 73.5 2.4 48.5 0.0 1.5 22.2 2.0 60.7 92.0 6.1 202.0 28.4 44.4 36.5 29.3 27.9 4.1 12.1 54.2 1.8 16.2 221.5 2.2 22.5 689.4 0.3 6.9 1.5 19.7 89.6 49.9 1.2 1.2 7.0 60.1 1.4 5.9 2.8 27.6 18.2 CYFIP2 PIR121 ENSG00000055163 "Cytoplasmic FMR1 interacting protein 2" Q96F07 5 157266079-157395595 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 112.2;kidney: 139.9" "Cell type enhanced" "Detected in many" "Astrocytes: 133.5;Collecting duct cells: 158.2;Distal tubular cells: 174.1;Excitatory neurons: 117.7;Inhibitory neurons: 147.5;Oligodendrocyte precursor cells: 120.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 202.4;JURKAT: 145.2;MOLT-4: 204.8;U-266/70: 153.6;U-698: 142.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB055519, HPA068106, HPA071459" Uncertain Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum" "Plasma membrane, Cytosol" "CAB055519: , HPA068106: AB_2685955, HPA071459: AB_2686400" "unprognostic (1.02e-2)" "unprognostic (1.30e-1)" "unprognostic (7.07e-2)" "prognostic unfavorable (2.42e-6)" "unprognostic (3.76e-1)" "unprognostic (4.58e-2)" "unprognostic (1.14e-1)" "unprognostic (6.91e-3)" "unprognostic (3.97e-2)" "unprognostic (5.25e-2)" "prognostic favorable (1.18e-4)" "unprognostic (3.81e-2)" "prognostic favorable (3.21e-12)" "unprognostic (2.90e-1)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (2.49e-2)" 3.2 12.3 61.0 30.8 54.4 55.5 2.8 23.6 103.8 3.1 16.3 8.9 6.3 6.6 25.1 3.8 9.2 8.8 10.4 112.2 25.6 139.9 18.3 12.2 57.1 8.4 33.4 4.8 7.1 64.9 40.1 9.3 6.6 5.8 9.8 35.4 4.0 5.0 7.0 2.8 17.5 5.6 0.0 35.0 20.9 5.3 67.7 85.9 9.9 1.7 55.3 8.3 2.3 37.7 0.3 31.8 47.3 28.8 1.1 1.3 81.5 6.1 9.6 2.5 6.8 6.2 0.6 202.4 14.5 3.4 7.4 0.4 38.0 27.1 5.8 48.8 60.8 28.4 42.3 24.9 4.1 29.1 71.8 5.4 10.9 8.1 0.5 18.8 8.8 145.2 0.4 81.1 7.0 7.7 204.8 5.5 22.3 0.5 8.5 50.6 1.4 102.3 24.5 30.2 70.5 27.4 0.6 28.3 4.6 46.8 19.9 0.8 11.3 2.0 21.4 7.1 5.4 153.6 40.2 142.8 21.4 33.5 11.8 64.8 12.6 90.1 85.9 57.4 61.0 35.8 60.6 75.7 17.8 35.9 63.2 73.2 41.0 53.9 133.7 43.9 53.5 78.0 61.0 54.4 23.6 103.8 112.2 25.6 8.4 33.4 6.6 0.0 67.7 37.7 1.8 3.2 26.9 133.5 76.6 1.1 2.2 2.8 3.4 62.0 3.5 3.4 17.9 8.6 7.4 158.2 16.7 37.2 78.8 6.0 174.1 9.7 15.3 2.8 1.8 2.6 14.4 11.6 117.7 1.6 43.0 3.6 6.1 6.2 2.5 23.1 5.7 30.8 5.3 90.9 147.5 5.6 4.1 6.5 11.4 24.2 1.8 15.7 7.2 23.4 20.3 14.0 101.0 120.6 33.8 1.9 9.9 6.8 41.1 1.3 5.4 55.0 4.7 35.2 0.0 12.2 11.0 3.2 13.1 0.8 1.4 21.1 88.8 2.1 9.1 1.7 CYTH2 "ARNO, CTS18.1, cytohesin-2, PSCD2, PSCD2L, Sec7p-L, Sec7p-like" ENSG00000105443 "Cytohesin 2" Q99418 19 48469208-48482314 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 285.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014872, HPA060662" Uncertain Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Cytosol "Golgi apparatus, Plasma membrane" "CAB014872: , HPA060662: AB_2732652" "unprognostic (2.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.60e-3)" "unprognostic (1.72e-1)" "unprognostic (4.97e-2)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.66e-1)" "unprognostic (2.83e-2)" "unprognostic (3.70e-1)" "unprognostic (1.85e-1)" "unprognostic (2.33e-2)" "unprognostic (9.19e-2)" "unprognostic (3.14e-1)" "unprognostic (1.22e-1)" "unprognostic (1.24e-1)" "prognostic favorable (3.21e-4)" 8.1 12.1 17.2 11.4 17.8 8.1 14.2 20.3 19.0 15.9 15.4 9.3 21.5 10.7 13.6 15.3 7.6 23.2 7.4 16.2 17.1 21.0 7.2 11.2 8.2 18.1 19.1 7.5 16.6 19.6 14.8 16.3 17.4 15.0 8.3 39.0 22.6 9.1 3.6 15.1 21.3 8.2 15.3 10.6 17.5 35.6 21.2 14.9 52.5 5.7 8.8 10.9 10.6 21.2 24.7 36.8 107.9 24.7 16.2 13.9 19.6 18.9 17.3 19.9 18.7 20.1 32.9 16.1 19.2 16.6 16.5 30.4 21.1 23.1 12.5 24.6 28.1 22.5 52.6 22.0 14.6 14.0 29.7 18.0 38.5 24.6 15.9 90.2 26.0 23.4 22.9 55.0 26.6 20.0 23.9 102.5 11.8 22.1 14.9 29.6 15.9 11.2 34.2 52.1 31.9 30.9 20.7 57.6 16.8 34.0 27.1 18.8 28.3 42.6 21.3 10.3 27.8 54.1 30.8 10.8 15.5 27.1 30.7 2.8 2.7 2.3 2.6 2.1 1.8 2.6 3.2 3.7 2.4 1.8 2.8 2.0 7.2 1.4 2.7 3.9 3.6 2.1 17.2 17.8 20.3 19.0 16.2 17.1 18.1 19.1 17.4 15.3 21.2 21.2 48.5 28.9 33.5 15.0 18.7 45.9 115.0 81.1 26.7 35.6 47.6 28.7 11.5 55.8 63.2 40.5 25.0 51.2 42.6 35.0 35.2 82.7 285.9 85.3 26.5 56.0 26.0 4.6 5.7 93.6 47.0 33.5 55.0 56.3 17.7 32.5 50.3 8.3 43.7 21.9 6.8 29.3 67.1 27.9 39.7 163.0 37.3 34.9 35.6 9.4 52.0 42.6 22.6 4.5 12.0 136.6 36.2 36.9 23.2 77.1 57.9 53.3 80.6 59.5 52.6 42.9 70.9 63.5 53.2 23.2 47.5 142.7 33.2 26.0 25.4 139.2 CYTH4 "CYT4, cytohesin-4, PSCD4" ENSG00000100055 "Cytohesin 4" Q9UIA0 22 37282027-37315341 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.3;lymphoid tissue: 67.3" "Cell type enhanced" "Detected in many" "dendritic cells: 117.5;granulocytes: 57.0;Hofbauer cells: 76.8;Kupffer cells: 71.5;Langerhans cells: 87.5;Macrophages: 55.0;NK-cells: 120.5;T-cells: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 34.1;HMC-1: 141.1;THP-1: 95.2;U-266/70: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004065, HPA071573" Approved Supported "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA004065: , HPA071573: AB_2686418" "unprognostic (4.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" "unprognostic (9.28e-3)" "unprognostic (9.25e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (5.84e-2)" "unprognostic (3.30e-3)" "unprognostic (1.23e-1)" "unprognostic (3.31e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (2.41e-8)" "unprognostic (3.70e-2)" "unprognostic (1.92e-2)" "unprognostic (5.56e-2)" "unprognostic (2.07e-1)" 21.5 8.8 4.9 67.3 4.5 58.3 5.1 4.4 8.5 5.3 6.0 10.7 8.5 4.4 1.6 6.1 4.8 16.4 5.6 4.7 5.6 4.1 5.7 18.9 57.0 8.8 7.4 3.4 2.5 2.1 2.9 28.0 7.8 3.6 10.0 0.3 7.3 4.3 2.2 2.2 15.2 12.9 6.7 59.2 11.5 2.7 9.7 25.6 3.0 5.1 40.3 23.2 2.5 9.1 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.8 9.3 0.3 0.0 2.5 0.1 0.0 0.6 0.0 5.3 0.0 9.8 0.0 0.0 0.0 34.1 141.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 23.2 0.0 0.0 0.5 13.5 0.0 0.1 1.0 1.3 0.2 19.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 95.2 0.3 0.0 0.1 0.1 0.0 28.4 4.0 4.5 18.5 11.5 0.2 15.8 62.6 87.5 55.4 102.5 39.0 30.3 30.5 44.8 47.5 31.8 30.0 38.3 199.1 45.0 129.4 113.8 30.7 76.2 4.9 4.5 4.4 8.5 4.7 5.6 8.8 7.4 7.8 6.7 9.7 9.1 1.1 3.2 8.4 0.0 37.0 2.4 0.8 0.0 0.6 0.1 0.7 1.5 2.0 0.0 1.8 0.0 0.0 0.5 117.5 0.1 0.0 0.0 0.4 0.1 0.2 2.5 0.0 2.5 0.2 0.2 0.6 1.9 2.0 0.1 57.0 0.0 2.2 1.1 76.8 0.0 0.2 0.2 0.0 71.5 87.5 0.9 0.6 55.0 7.2 24.4 42.7 0.0 120.5 0.5 0.0 0.8 0.0 0.0 25.1 0.3 0.0 0.8 0.0 0.1 0.0 0.9 1.0 0.0 0.2 0.3 2.3 1.0 43.9 0.0 0.2 0.5 DAG1 "156DAG, A3a, AGRNR, DAG" ENSG00000173402 "Dystroglycan 1" Q14118 3 49468703-49535618 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 207.9;Skeletal myocytes: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 280.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001960, CAB016353, HPA070563" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 84000000 "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Plasma membrane" Nucleoplasm "CAB001960: , CAB016353: AB_627292, HPA070563: " "unprognostic (1.58e-1)" "unprognostic (5.14e-1)" "unprognostic (6.71e-3)" "unprognostic (3.32e-1)" "unprognostic (7.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.67e-1)" "unprognostic (3.27e-2)" "unprognostic (8.18e-2)" "unprognostic (3.91e-2)" "unprognostic (5.70e-3)" "unprognostic (1.10e-1)" "prognostic favorable (2.59e-4)" "unprognostic (9.22e-2)" "unprognostic (1.99e-2)" "unprognostic (7.43e-2)" "unprognostic (1.57e-2)" 25.2 22.0 31.5 17.9 32.6 5.4 26.6 30.7 30.7 26.2 25.5 38.8 24.0 32.1 16.2 28.3 31.8 26.4 68.9 30.1 28.9 28.1 43.0 31.8 9.4 33.3 31.4 24.6 51.4 44.3 18.6 77.0 28.6 29.5 30.6 9.8 31.8 37.9 93.8 28.5 24.0 45.9 30.2 12.6 32.0 26.9 34.1 10.5 25.5 95.7 14.3 27.8 22.0 31.2 92.3 92.4 61.9 152.3 80.3 38.8 280.9 63.9 93.7 108.0 69.0 74.2 96.0 13.0 62.2 103.2 87.6 168.4 55.6 81.2 67.2 12.7 18.6 9.6 84.3 87.2 35.5 11.2 17.4 33.3 72.5 100.3 33.3 96.7 97.1 15.3 14.5 9.8 31.2 75.5 10.1 8.1 66.4 110.0 31.2 5.5 60.5 22.3 82.5 126.4 21.8 45.2 74.8 206.0 105.5 170.3 171.6 22.8 51.8 39.1 63.9 76.0 91.4 11.0 24.2 8.1 50.4 12.6 245.9 2.3 1.2 0.7 1.1 1.3 1.2 1.2 0.9 0.9 0.7 1.0 1.0 1.0 2.2 1.1 2.5 1.3 0.7 1.4 31.5 32.6 30.7 30.7 30.1 28.9 33.3 31.4 28.6 30.2 34.1 31.2 19.0 54.5 18.4 32.0 4.0 14.3 8.0 31.7 17.1 7.4 36.1 46.4 56.6 30.0 20.6 35.0 4.2 116.4 5.8 37.3 1.9 32.4 30.0 30.2 17.3 20.9 33.0 14.3 15.6 79.6 118.4 26.1 37.8 37.9 7.0 207.9 16.8 59.9 21.2 3.3 16.5 29.7 14.2 8.6 7.0 20.0 21.5 6.3 33.8 9.4 5.6 27.1 5.2 19.6 10.7 57.2 21.4 36.9 5.1 14.4 18.9 7.6 23.2 8.7 46.0 326.1 36.2 7.1 19.9 19.0 17.0 95.9 5.9 10.0 29.2 10.2 DAGLB "DAGLBETA, KCCR13L" ENSG00000164535 "Diacylglycerol lipase beta" Q8NCG7 7 6409126-6484190 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069377 Supported "Nucleoplasm,Plasma membrane" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA069377: AB_2686132" "unprognostic (2.39e-1)" "unprognostic (4.61e-2)" "unprognostic (2.13e-3)" "unprognostic (1.42e-1)" "unprognostic (9.04e-3)" "unprognostic (3.68e-2)" "unprognostic (1.78e-3)" "unprognostic (2.36e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (7.18e-5)" "unprognostic (1.25e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (2.18e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (1.81e-2)" 7.3 15.6 9.9 6.7 9.9 15.0 6.6 7.3 11.1 7.0 5.9 6.7 7.6 5.8 3.6 8.0 5.9 6.4 5.6 11.2 8.8 4.9 7.9 9.3 7.4 9.7 7.7 7.9 6.9 7.0 4.3 8.7 8.0 5.3 5.0 3.4 7.7 4.5 13.3 12.4 7.6 5.8 8.4 8.5 7.1 5.5 8.1 8.1 7.5 7.0 6.7 5.8 7.3 10.7 21.6 23.9 10.9 14.3 16.1 12.5 8.4 29.8 21.3 26.6 28.7 13.6 24.4 12.3 12.5 15.4 64.8 32.4 17.8 16.7 15.2 5.8 11.7 6.6 26.9 9.4 17.3 18.8 10.1 11.3 27.2 17.9 17.5 10.7 11.7 15.6 18.2 6.1 15.9 16.2 6.7 26.9 39.6 11.3 18.5 57.4 12.7 25.5 16.8 8.1 13.5 8.4 17.7 26.7 5.3 17.2 19.0 34.7 14.4 22.4 41.9 28.1 13.9 6.2 11.2 10.4 11.3 28.9 28.2 10.8 22.8 22.0 6.2 21.3 5.5 8.2 4.8 4.1 28.6 4.7 11.4 6.7 10.2 3.9 19.5 5.0 4.3 12.2 9.9 9.9 7.3 11.1 11.2 8.8 9.7 7.7 8.0 8.4 8.1 10.7 6.5 9.6 12.6 5.9 7.9 16.8 3.6 6.2 12.0 4.5 5.7 5.7 3.1 4.3 5.0 5.5 2.1 5.1 4.8 12.2 0.0 7.0 0.4 10.3 6.8 9.0 2.4 13.3 13.8 6.2 8.9 5.4 19.4 19.9 3.8 5.5 8.9 8.0 17.2 0.0 9.2 5.8 6.1 16.1 17.4 1.7 6.2 16.3 5.4 26.2 15.8 1.4 7.2 2.5 6.5 12.2 8.0 2.2 5.0 5.7 10.6 1.6 3.8 4.3 0.0 4.0 5.0 8.5 7.1 9.4 13.4 12.4 6.7 7.4 7.6 4.3 DBNL "ABP1, HIP-55, SH3P7" ENSG00000136279 "Drebrin like" Q9UJU6 7 44044640-44069456 "Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Endocytosis, Immunity, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 338.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020265, HPA027735" Enhanced Supported "Vesicles,Plasma membrane" NA NA 3500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Vesicles, Plasma membrane" "HPA020265: AB_1850723, HPA027735: AB_10603790" "unprognostic (9.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.04e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.12e-5)" "unprognostic (2.25e-1)" "unprognostic (6.18e-3)" "unprognostic (1.83e-1)" "unprognostic (5.88e-2)" "unprognostic (8.92e-2)" "unprognostic (5.76e-3)" "unprognostic (5.92e-2)" "unprognostic (2.11e-1)" "unprognostic (1.79e-1)" "unprognostic (2.10e-1)" "unprognostic (1.46e-1)" "unprognostic (9.51e-2)" 58.1 51.6 44.2 62.8 45.1 76.6 51.3 41.7 50.4 72.4 39.9 54.6 34.7 56.0 20.2 189.0 47.8 47.2 49.2 45.8 45.2 50.7 51.1 57.8 99.6 46.2 44.8 38.0 44.3 38.4 47.8 34.9 48.4 57.0 30.6 9.4 57.5 38.0 34.3 59.9 64.7 44.8 44.3 119.5 54.7 20.8 44.6 64.8 47.6 16.4 89.1 60.3 92.0 43.4 57.6 89.1 60.5 56.6 77.0 49.7 46.0 95.9 93.6 111.5 91.5 90.0 82.5 132.3 70.0 126.1 133.6 101.9 35.6 130.6 40.7 70.6 38.9 51.9 73.8 52.4 78.5 75.8 70.3 46.6 53.3 107.1 35.2 71.5 74.1 83.9 63.8 49.3 105.5 91.5 136.5 85.3 43.1 72.9 73.0 69.4 48.1 64.5 69.8 90.5 65.6 89.8 69.6 121.5 24.4 43.8 94.0 99.4 121.1 82.7 75.5 49.5 113.6 102.7 49.4 81.2 78.3 83.2 183.8 263.3 377.1 295.0 190.3 422.7 148.3 253.9 138.0 155.0 362.5 261.7 136.5 145.1 357.4 192.4 437.9 376.6 183.1 558.8 44.2 45.1 41.7 50.4 45.8 45.2 46.2 44.8 48.4 44.3 44.6 43.4 49.9 44.8 36.2 10.7 105.4 17.6 34.1 62.9 19.4 33.0 26.7 24.0 30.6 25.8 42.2 31.3 35.5 78.9 101.6 58.5 45.0 87.0 10.3 30.7 39.3 44.8 37.8 45.8 7.4 73.2 146.4 39.3 54.6 50.7 65.9 42.3 32.5 22.5 176.0 40.4 6.7 50.0 38.7 129.6 48.6 10.6 37.0 113.4 55.2 7.5 338.3 42.5 112.3 5.5 11.4 105.9 74.0 33.8 50.2 31.5 49.0 33.6 21.6 38.6 6.6 29.0 54.6 24.4 12.8 64.4 26.7 87.3 69.5 51.9 44.0 51.1 DCT TYRP2 ENSG00000080166 "Dopachrome tautomerase" P40126 13 94436811-94479682 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "skin 1: 107.4" "Cell type enriched" "Detected in some" 23 "Melanocytes: 3552.1" "Cancer enriched" "Detected in some" 215 "melanoma: 155.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 272 "SK-MEL-30: 257.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA010742, HPA010743, HPA010800, CAB017634" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Vesicles "CAB017634: AB_1130818, HPA010742: , HPA010743: AB_1847519, HPA010800: AB_1847520" "unprognostic (5.99e-2)" "unprognostic (1.67e-2)" "unprognostic (1.54e-2)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" "unprognostic (3.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.81e-2)" "unprognostic (6.07e-2)" "unprognostic (1.81e-1)" "unprognostic (3.64e-3)" "unprognostic (1.06e-2)" "unprognostic (6.18e-5)" "unprognostic (6.97e-2)" "unprognostic (9.87e-2)" "unprognostic (1.22e-3)" "unprognostic (2.42e-1)" 0.4 0.4 0.6 0.0 1.0 0.1 3.0 0.4 0.7 0.2 0.2 0.3 0.0 0.3 0.9 0.0 0.9 0.1 0.1 0.6 0.6 0.2 0.2 0.1 0.0 0.6 0.6 0.4 0.4 0.0 1.6 0.0 0.5 0.3 0.0 0.9 1.5 0.3 0.4 107.4 0.1 0.1 0.6 0.1 0.1 0.6 0.6 0.5 0.2 0.1 0.0 0.2 0.3 0.5 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 257.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.2 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.4 0.7 0.6 0.6 0.6 0.6 0.5 0.6 0.6 0.5 0.0 0.0 0.0 23.5 0.0 152.3 0.1 0.0 0.0 1.0 0.3 0.5 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.5 0.1 1.2 0.0 0.0 16.1 0.2 0.0 1.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 25.5 23.8 0.9 0.0 3552.1 1.9 0.0 3.5 0.0 6.6 2.4 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.5 1.0 0.5 0.8 0.0 33.4 0.0 0.9 0.1 0.0 0.0 DCTN6 WS-3 ENSG00000104671 "Dynactin subunit 6" O00399 8 30156319-30183639 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024049, HPA024558" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Cytosol" "Plasma membrane" "HPA024049: AB_1847524, HPA024558: AB_1847525" "unprognostic (1.28e-1)" "unprognostic (8.32e-3)" "unprognostic (1.65e-2)" "unprognostic (1.88e-1)" "unprognostic (1.69e-1)" "unprognostic (7.50e-2)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.26e-1)" "unprognostic (7.84e-2)" "unprognostic (1.08e-2)" "unprognostic (2.38e-2)" "unprognostic (9.26e-2)" "prognostic favorable (5.42e-4)" "unprognostic (1.06e-1)" "unprognostic (3.10e-1)" "unprognostic (7.54e-2)" "unprognostic (1.43e-1)" 50.6 54.1 48.0 26.6 51.1 43.7 53.0 51.8 74.1 32.3 42.3 37.5 23.8 38.2 43.5 34.3 30.1 32.8 75.6 50.4 54.8 54.2 46.7 34.0 28.3 50.8 49.8 41.5 32.0 72.8 29.7 53.6 51.1 34.7 36.2 42.4 33.6 36.7 36.6 29.0 26.1 42.6 52.9 27.6 31.9 21.9 50.5 37.8 54.6 43.5 31.2 45.8 31.6 58.6 53.6 51.9 64.4 33.8 59.3 80.7 42.1 72.8 87.0 70.4 74.9 33.6 35.8 41.0 76.0 78.8 64.9 39.6 46.1 64.2 83.8 32.4 34.3 57.8 40.9 54.5 45.8 33.6 47.4 68.2 90.4 51.2 54.8 61.5 65.2 58.0 66.4 44.3 77.0 41.7 62.4 53.0 51.6 93.8 32.0 32.4 48.7 35.3 104.6 54.1 105.4 60.0 42.7 53.0 77.9 32.4 50.4 48.3 60.8 37.4 128.9 31.9 52.4 18.1 22.2 51.8 69.7 38.1 68.1 16.7 13.5 5.0 8.1 15.8 9.1 7.1 7.5 9.8 15.9 5.3 9.5 11.4 3.7 11.2 15.9 20.8 8.1 6.8 48.0 51.1 51.8 74.1 50.4 54.8 50.8 49.8 51.1 52.9 50.5 58.6 61.3 25.6 39.7 19.9 34.9 57.2 91.3 127.1 25.6 36.4 45.4 43.2 83.4 47.1 85.3 44.1 14.6 88.5 48.9 28.1 123.3 94.5 18.0 32.5 37.2 58.7 40.8 28.2 19.0 84.5 87.7 56.6 25.0 39.6 46.9 44.0 45.7 42.7 71.4 26.9 17.3 31.6 91.6 43.9 54.8 12.5 80.8 43.2 69.4 15.0 58.4 63.3 17.5 17.6 21.3 91.1 43.1 75.2 32.3 48.8 36.3 147.1 71.6 40.3 52.6 63.1 66.0 44.2 47.3 38.0 63.5 203.6 59.8 49.5 33.0 95.0 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 89.8;Fibroblasts: 116.5;Leydig cells: 63.0;Peritubular cells: 88.4;Skeletal myocytes: 98.2;Smooth muscle cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 233.3;ASC TERT1: 214.4;BJ hTERT+: 163.4;fHDF/TERT166: 137.6;HSkMC: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 770000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA070112: AB_2686229" "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 59.8 64.3 13.2 15.8 11.3 0.3 25.2 10.4 9.2 33.7 51.5 54.7 5.8 26.2 13.2 18.1 22.4 23.8 24.1 12.6 24.5 6.4 5.4 14.5 9.1 37.0 22.1 37.4 3.7 2.5 5.4 10.6 31.7 17.3 14.1 5.1 9.8 29.2 4.9 9.7 17.6 42.8 17.8 5.8 20.4 3.9 21.0 3.3 12.9 19.3 6.9 23.2 23.6 25.2 0.3 0.0 0.2 63.2 233.3 214.4 1.0 92.2 163.4 41.5 56.8 0.0 0.2 0.0 0.1 137.6 8.9 0.1 0.3 0.4 54.0 42.9 0.3 0.0 0.4 0.1 103.9 0.2 0.2 157.0 0.4 73.1 2.2 65.8 46.0 0.4 0.6 16.8 36.9 0.1 0.0 0.3 0.4 0.1 0.3 0.1 24.1 0.7 0.2 0.2 0.3 35.4 0.2 0.1 2.9 3.6 0.2 0.3 2.1 58.5 13.8 29.1 12.6 2.6 4.0 0.1 56.3 0.1 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 11.3 10.4 9.2 12.6 24.5 37.0 22.1 31.7 17.8 21.0 25.2 23.4 3.2 2.3 53.2 2.5 12.6 3.9 0.8 1.2 3.0 6.0 15.6 31.3 1.5 1.1 0.0 0.0 0.5 1.7 3.2 0.0 0.4 8.9 5.0 89.8 22.3 1.2 0.0 13.1 1.8 0.5 116.5 2.6 8.2 1.3 16.7 30.0 3.5 1.2 0.0 26.2 1.0 0.0 1.9 19.3 7.1 63.0 3.1 23.2 29.0 0.0 16.5 2.1 6.0 5.6 1.8 4.4 88.4 5.6 5.9 1.2 2.1 2.4 3.0 39.5 98.2 78.3 1.0 0.9 2.0 8.7 1.0 2.5 34.2 0.8 4.2 DGKG DAGK3 ENSG00000058866 "Diacylglycerol kinase gamma" P49619 3 186105668-186362234 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.2" "Cell type enhanced" "Detected in many" "Astrocytes: 223.0;Excitatory neurons: 111.0;Inhibitory neurons: 63.5;Oligodendrocyte precursor cells: 334.8" "Cancer enhanced" "Detected in some" "glioma: 2.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "classical monocyte: 2.1;eosinophil: 1.2;intermediate monocyte: 1.2;myeloid DC: 1.5;neutrophil: 2.6;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "dendritic cells: 1.5;granulocytes: 2.6;monocytes: 2.1" "Cell line enhanced" "Detected in some" "HDLM-2: 23.9;HL-60: 7.7;U-266/84: 9.4;U-87 MG: 14.3;U-937: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036577 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Plasma membrane" "HPA036577: AB_10672358" "unprognostic (2.23e-1)" "unprognostic (1.97e-1)" "unprognostic (1.56e-2)" "unprognostic (3.24e-5)" "unprognostic (2.70e-1)" "unprognostic (6.09e-4)" "unprognostic (1.21e-3)" "unprognostic (3.80e-2)" "unprognostic (5.88e-2)" "unprognostic (1.50e-1)" "unprognostic (1.94e-1)" "unprognostic (5.09e-2)" "unprognostic (8.05e-7)" "unprognostic (3.47e-3)" "unprognostic (7.19e-2)" "unprognostic (1.41e-1)" "unprognostic (9.16e-3)" 1.6 4.2 14.2 0.8 17.4 9.3 1.1 28.2 11.9 2.2 0.0 3.2 1.4 1.2 8.0 4.6 4.1 0.9 9.1 20.4 3.6 1.3 0.8 3.8 0.9 20.1 6.5 1.2 0.5 5.7 6.0 7.8 20.8 1.3 0.8 1.7 0.8 1.8 1.8 0.8 1.7 2.4 0.6 0.9 2.1 0.3 9.6 0.5 1.8 1.0 0.8 3.4 1.7 13.2 3.2 4.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 2.7 0.0 3.3 0.2 0.0 0.0 0.0 23.9 0.0 3.2 0.0 3.5 0.0 7.7 0.3 0.0 0.0 1.4 0.0 0.1 0.0 0.6 0.0 0.4 0.4 0.1 0.1 2.6 0.4 0.0 1.4 1.7 0.0 2.6 0.0 0.0 0.6 0.0 0.9 0.0 2.0 0.0 0.1 4.9 0.0 0.0 0.8 2.4 2.9 0.0 9.4 0.0 14.3 7.0 2.6 0.0 2.1 1.2 0.0 1.2 0.0 0.3 0.0 0.0 1.5 0.1 0.0 0.0 2.6 0.0 1.5 0.2 0.0 0.7 14.2 17.4 28.2 11.9 20.4 3.6 20.1 6.5 20.8 0.6 9.6 13.2 0.1 0.0 1.7 223.0 3.1 0.4 0.2 0.0 0.6 0.1 0.1 0.4 19.4 1.5 0.0 1.8 0.0 0.1 0.0 0.0 0.0 1.4 2.6 0.3 0.1 5.0 0.0 0.4 111.0 1.2 0.0 0.5 0.5 0.1 0.0 0.3 22.1 0.0 2.1 1.7 63.5 0.1 0.0 3.2 1.4 4.2 1.8 3.4 0.0 12.2 5.2 6.8 0.0 334.8 7.8 1.0 0.1 0.4 0.2 0.4 0.1 0.9 0.0 0.1 13.1 1.8 14.5 0.0 0.2 0.4 0.4 0.1 0.1 0.9 0.1 0.4 DGKH DGKeta ENSG00000102780 "Diacylglycerol kinase eta" Q86XP1 13 42040036-42256578 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.8" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 137.8;Urothelial cells: 147.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 25.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039533, HPA040355, HPA061538" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "HPA039533: AB_10795145, HPA040355: AB_10796452, HPA061538: " "unprognostic (2.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.30e-1)" "unprognostic (5.69e-2)" "unprognostic (1.55e-3)" "unprognostic (7.62e-2)" "unprognostic (1.04e-2)" "unprognostic (9.60e-2)" "unprognostic (7.00e-3)" "unprognostic (4.37e-2)" "unprognostic (1.86e-1)" "unprognostic (2.41e-1)" "unprognostic (3.43e-3)" "unprognostic (1.03e-1)" "unprognostic (1.67e-1)" "unprognostic (4.93e-2)" "unprognostic (1.43e-2)" 3.7 1.3 4.5 2.0 25.8 1.3 3.5 8.7 5.4 4.4 0.0 3.7 1.5 6.4 6.9 4.1 4.3 2.5 3.0 7.3 4.4 3.3 1.0 7.8 2.2 0.0 7.4 2.8 1.0 0.7 2.6 4.5 0.4 2.8 3.3 2.6 3.0 2.1 1.5 3.2 2.7 4.0 0.2 1.7 2.6 2.3 9.7 2.7 2.5 2.2 1.3 5.3 4.6 2.8 5.6 6.6 4.3 3.6 1.9 4.2 0.5 3.4 2.7 2.2 2.8 0.6 4.7 4.3 4.1 3.7 8.3 11.8 3.8 7.7 3.3 3.4 12.4 7.6 3.6 0.4 2.4 3.3 2.0 1.6 7.7 4.3 17.0 3.4 9.9 5.3 3.0 2.9 3.8 5.1 3.4 1.7 1.9 5.2 4.3 5.0 3.8 2.9 7.4 16.7 2.5 2.6 3.1 4.0 3.0 1.8 3.4 8.9 9.8 4.1 3.8 4.5 4.7 1.5 1.5 4.8 2.4 2.9 3.1 0.6 0.3 0.1 0.2 0.2 0.2 0.1 0.4 0.4 0.0 0.2 0.2 0.4 0.9 0.1 0.1 0.3 0.3 0.1 4.5 25.8 8.7 5.4 7.3 4.4 0.0 7.4 0.4 0.2 9.7 2.8 64.8 22.4 20.1 8.8 1.9 61.7 58.1 61.1 15.9 44.5 13.6 8.9 8.5 24.3 44.7 11.0 4.2 3.7 2.2 29.0 1.9 11.3 25.9 64.1 26.0 50.8 47.4 2.7 85.4 7.2 2.2 17.5 15.3 46.2 7.6 5.7 23.2 3.2 6.8 1.7 60.2 18.7 14.2 5.6 43.1 20.1 3.4 8.0 8.8 56.2 8.6 18.8 1.0 54.3 11.0 27.6 19.2 9.1 6.2 137.8 13.1 8.4 91.8 2.6 26.3 16.2 54.1 3.8 3.8 19.7 33.1 2.9 13.0 11.5 22.0 147.3 DIAPH3 "AN, AUNA1, DRF3, FLJ34705, NSDAN" ENSG00000139734 "Diaphanous related formin 3" Q9NSV4 13 59665583-60163928 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.1;testis: 18.9" "Cell type enriched" "Detected in many" 5 "Early spermatids: 414.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032151 Supported "Plasma membrane,Microtubules" NA Yes "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Microtubules" "HPA032151: AB_2674181" "unprognostic (3.78e-2)" "unprognostic (1.28e-2)" "prognostic favorable (9.04e-4)" "prognostic unfavorable (4.18e-4)" "unprognostic (2.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.27e-4)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.74e-2)" "unprognostic (2.19e-1)" "unprognostic (5.22e-5)" "unprognostic (3.59e-3)" "unprognostic (5.31e-5)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (4.07e-1)" "unprognostic (2.74e-3)" 0.4 0.1 0.1 1.7 0.2 7.1 0.8 0.3 0.3 0.3 0.2 1.9 1.9 0.6 0.0 2.1 0.1 0.4 0.1 0.1 0.2 0.8 0.2 1.2 2.4 0.2 0.3 0.1 0.2 0.1 0.0 3.5 0.2 0.1 2.1 0.0 0.5 0.0 0.0 1.3 1.6 2.6 0.1 0.5 1.6 18.9 0.3 5.4 0.1 0.0 2.4 0.6 0.7 0.2 47.7 15.6 15.8 9.1 2.7 7.1 26.9 65.0 28.7 64.2 55.6 41.7 31.4 15.9 5.2 33.4 16.7 31.7 26.0 25.5 96.9 18.0 17.9 22.7 37.6 9.5 4.1 31.2 17.4 2.8 0.6 39.2 26.3 16.3 29.2 14.0 17.8 21.9 61.8 6.9 28.0 10.2 14.7 22.5 8.9 18.8 38.9 12.9 19.9 9.6 8.3 14.3 33.2 22.8 9.5 33.8 16.7 16.8 29.3 40.5 25.9 13.7 54.5 14.7 17.1 24.4 10.9 15.2 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.3 0.3 0.1 0.2 0.2 0.3 0.2 0.1 0.3 0.2 0.6 54.5 3.4 39.8 1.9 3.7 0.8 2.1 2.8 0.0 3.9 1.5 1.0 2.8 1.8 0.0 0.0 21.1 1.1 3.8 5.9 1.3 414.4 2.5 3.5 2.1 0.0 26.7 5.6 4.0 30.7 5.8 9.7 9.3 0.0 78.8 1.8 0.4 6.1 0.0 3.3 2.6 2.0 1.0 1.2 56.0 0.6 1.5 0.0 5.6 0.1 3.5 2.1 19.1 1.8 1.5 0.2 0.0 18.9 0.4 1.1 5.4 0.2 0.0 0.0 0.0 7.9 39.2 17.8 11.6 1.1 7.3 2.2 2.8 5.6 1.5 DNAJC5 "CLN4, DNAJC5A, FLJ00118, FLJ13070" ENSG00000101152 "DnaJ heat shock protein family (Hsp40) member C5" Q9H3Z4 20 63895126-63936031 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012139, HPA012737, HPA013154" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Plasma membrane" Vesicles "HPA012139: , HPA012737: AB_1847293, HPA013154: AB_1847292" "unprognostic (9.96e-3)" "unprognostic (2.75e-1)" "unprognostic (3.91e-1)" "unprognostic (3.61e-2)" "unprognostic (1.65e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (8.82e-6)" "unprognostic (3.04e-2)" "unprognostic (2.73e-1)" "unprognostic (2.65e-2)" "unprognostic (1.78e-3)" "unprognostic (1.51e-1)" "prognostic favorable (7.70e-6)" "unprognostic (2.24e-2)" "unprognostic (3.54e-2)" "unprognostic (4.28e-3)" "unprognostic (1.08e-2)" 12.6 22.1 30.8 10.7 33.0 16.9 11.1 10.2 39.1 11.4 2.1 17.6 11.5 12.1 5.7 42.0 11.6 7.4 25.8 36.2 31.0 17.7 12.8 18.0 9.9 27.9 23.9 8.8 22.7 21.2 28.5 8.4 30.4 16.7 6.9 28.1 16.2 11.5 14.5 19.2 17.5 8.6 13.8 22.2 20.8 10.7 26.8 8.4 16.8 9.5 8.5 13.4 16.9 25.7 25.2 23.7 19.8 18.8 19.4 15.9 14.6 28.6 27.4 49.4 23.8 52.7 30.2 9.8 31.6 28.2 22.7 36.4 15.9 53.6 16.0 8.2 11.3 19.3 17.4 25.8 18.1 19.2 43.5 18.0 39.9 22.9 11.7 19.1 24.2 16.5 19.2 8.9 22.6 17.3 21.1 30.9 7.1 21.0 26.5 21.0 10.9 10.7 16.4 22.6 21.4 13.9 30.8 48.7 17.8 11.6 23.5 75.9 43.7 42.6 14.4 20.4 21.5 11.1 5.6 13.6 42.9 25.3 25.4 0.7 3.2 2.6 3.2 3.7 1.8 1.6 1.8 2.7 2.5 1.4 2.5 2.5 3.1 1.5 3.1 3.9 3.1 2.6 30.8 33.0 10.2 39.1 36.2 31.0 27.9 23.9 30.4 13.8 26.8 25.7 12.8 6.4 17.8 19.2 10.4 20.8 18.5 25.5 20.5 60.7 17.4 14.1 31.7 14.3 23.2 23.9 62.6 18.5 19.1 71.7 13.7 20.5 48.9 23.9 8.5 18.7 32.4 10.3 37.1 37.6 18.4 12.4 27.0 23.5 1.3 12.1 23.9 27.8 43.5 79.1 38.8 33.3 14.2 51.0 24.8 123.5 7.2 31.4 14.2 25.3 36.9 27.9 22.6 19.1 26.2 59.0 41.1 12.4 17.3 39.5 62.0 22.9 29.4 47.0 13.1 9.0 13.1 13.5 13.2 28.0 22.9 30.2 15.0 13.3 28.4 64.5 DNAJC9 "JDD1, SB73" ENSG00000213551 "DnaJ heat shock protein family (Hsp40) member C9" Q8WXX5 10 73183362-73247255 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 91.9" "Cell type enhanced" "Detected in all" "Erythroid cells: 173.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035215, HPA035216" Supported Supported "Nucleoplasm,Plasma membrane" NA NA 39000 "Cluster 44: Non-specific - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Plasma membrane" "HPA035215: AB_10603663, HPA035216: AB_2674522" "unprognostic (4.18e-2)" "unprognostic (1.61e-2)" "unprognostic (7.63e-2)" "unprognostic (2.67e-3)" "unprognostic (3.45e-1)" "unprognostic (6.83e-3)" "unprognostic (2.43e-3)" "prognostic unfavorable (3.26e-4)" "unprognostic (6.20e-2)" "unprognostic (1.66e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (7.07e-5)" "unprognostic (5.61e-2)" "unprognostic (3.08e-3)" "unprognostic (6.49e-2)" "unprognostic (3.38e-1)" "unprognostic (1.56e-1)" 9.2 10.6 17.1 17.6 17.5 91.9 15.4 19.2 21.5 11.2 15.4 16.0 14.6 12.8 12.4 16.9 9.7 6.9 8.6 16.9 17.0 10.0 13.4 9.6 28.2 16.4 16.5 15.3 8.7 10.2 10.6 17.6 16.9 11.4 18.0 25.1 11.3 11.2 11.5 17.7 13.9 11.8 15.7 14.8 12.2 12.4 17.0 35.8 8.4 13.1 32.3 11.5 11.9 17.6 135.0 77.3 93.8 68.4 16.1 19.3 45.7 101.5 59.4 101.1 106.1 130.8 89.4 86.9 33.5 43.6 43.7 83.1 92.9 67.5 118.1 98.5 63.8 188.3 79.4 93.4 14.8 173.1 71.0 14.8 33.2 107.1 93.4 36.4 66.2 112.1 168.3 103.0 81.4 118.4 155.0 124.7 36.3 64.4 215.1 114.2 85.1 47.6 52.9 61.5 44.3 73.4 73.5 114.5 52.9 43.7 62.1 76.8 48.0 65.2 118.3 71.3 168.0 45.0 70.6 141.8 64.8 162.9 45.9 23.9 3.7 29.1 25.5 10.7 29.2 32.8 31.3 28.2 6.5 28.3 30.3 26.9 4.5 24.8 10.9 20.3 36.8 18.0 17.1 17.5 19.2 21.5 16.9 17.0 16.4 16.5 16.9 15.7 17.0 17.6 17.3 9.6 12.3 11.1 39.5 47.7 34.1 31.9 33.0 26.1 21.5 24.8 2.7 17.2 24.8 9.2 8.4 107.8 44.6 18.3 21.5 31.5 80.4 15.9 14.0 20.6 12.0 173.8 11.8 31.4 111.4 17.6 12.2 19.0 42.3 26.0 13.9 9.8 61.9 15.2 12.8 25.6 54.9 10.9 19.6 43.3 14.0 17.4 32.0 6.5 23.0 29.5 32.0 7.5 6.5 44.1 16.7 20.3 49.7 27.6 18.2 16.3 21.9 43.2 26.3 17.7 28.3 28.7 65.4 38.2 43.5 58.0 45.2 19.7 38.0 37.5 DOCK4 "FLJ34238, KIAA0716" ENSG00000128512 "Dedicator of cytokinesis 4" Q8N1I0 7 111726110-112206407 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.6" "Group enriched" "Detected in many" 4 "Astrocytes: 791.0;Excitatory neurons: 422.8;Microglial cells: 1568.3;Oligodendrocyte precursor cells: 434.3;Oligodendrocytes: 815.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.7" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 43.3;HUVEC TERT2: 75.5;TIME: 69.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071516 Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Plasma membrane" "Golgi apparatus, Cytosol" "HPA071516: AB_2686407" "unprognostic (1.37e-1)" "unprognostic (4.18e-1)" "unprognostic (1.53e-1)" "unprognostic (2.48e-2)" "unprognostic (7.10e-2)" "unprognostic (2.03e-2)" "unprognostic (9.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" "unprognostic (5.78e-2)" "unprognostic (7.06e-2)" "unprognostic (3.66e-1)" "unprognostic (5.71e-2)" "unprognostic (1.89e-2)" "unprognostic (9.48e-2)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" 7.8 4.4 17.1 6.6 41.6 1.4 4.8 11.4 21.9 5.0 0.0 3.2 1.5 4.6 2.8 2.5 5.2 5.0 4.9 40.6 17.8 4.5 10.0 17.3 2.7 16.5 18.1 8.4 3.2 3.3 3.2 6.9 15.6 4.0 2.8 10.5 3.3 2.5 6.2 2.5 2.4 7.3 14.9 1.8 2.2 2.1 19.2 1.7 3.5 7.3 2.2 3.7 3.5 26.0 0.1 3.5 8.8 7.8 7.2 10.4 5.3 1.0 9.6 1.7 2.8 0.0 0.2 0.8 7.6 2.3 2.0 0.5 1.5 8.8 6.5 2.9 12.9 0.4 5.8 14.3 5.1 1.1 0.4 4.9 1.0 43.3 20.8 3.0 75.5 3.4 0.1 22.6 3.8 1.0 2.0 0.7 5.1 1.5 15.8 0.8 7.0 3.6 6.0 0.5 1.9 7.5 6.2 4.3 5.8 8.2 0.8 0.4 69.0 6.6 3.4 13.7 3.0 1.2 0.5 0.9 0.7 1.8 16.5 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.1 0.1 0.0 0.1 17.1 41.6 11.4 21.9 40.6 17.8 16.5 18.1 15.6 14.9 19.2 26.0 56.4 48.1 6.8 791.0 1.1 5.2 3.3 7.5 8.6 27.4 3.7 6.3 13.1 2.8 16.7 3.7 22.9 0.3 0.1 2.3 0.0 2.1 3.8 1.3 5.5 47.1 10.9 5.3 422.8 0.4 0.2 21.4 0.5 2.2 2.5 5.0 43.9 17.0 14.6 94.2 177.1 0.7 14.2 16.7 21.0 1.5 5.6 27.4 8.8 1568.3 6.1 5.4 0.0 434.3 815.3 1.2 8.0 8.2 0.2 8.2 0.0 1.8 12.2 11.4 13.1 4.2 5.8 0.6 1.9 2.3 2.7 0.0 0.6 26.2 1.5 1.8 DOK3 FLJ22570 ENSG00000146094 "Docking protein 3" Q7L591 5 177501904-177511274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 93.6;lymphoid tissue: 118.4" "Group enriched" "Detected in many" 5 "B-cells: 31.6;granulocytes: 18.3;Hofbauer cells: 55.7;Kupffer cells: 51.1;Macrophages: 38.3;monocytes: 45.4;Plasma cells: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 133.6" "Group enriched" "Detected in many" 6 "B-cells: 37.2;granulocytes: 133.6;monocytes: 77.6" "Cell line enhanced" "Detected in many" "Daudi: 124.0;HMC-1: 87.5;REH: 148.6;U-698: 122.1;U-937: 88.0" "Low region specificity" "Detected in many" HPA077312 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes NA 240000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA077312: AB_2732339" "unprognostic (2.21e-2)" "unprognostic (1.14e-2)" "unprognostic (2.05e-2)" "unprognostic (5.74e-3)" "unprognostic (2.32e-2)" "unprognostic (1.34e-3)" "unprognostic (4.17e-2)" "unprognostic (2.20e-1)" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.82e-11)" "unprognostic (1.34e-1)" "unprognostic (7.25e-2)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 11.0 6.1 5.2 30.2 6.2 93.6 4.4 6.5 7.9 3.2 6.3 8.2 6.5 3.4 1.7 5.5 7.8 4.3 4.1 6.0 7.0 5.0 6.5 27.1 31.5 11.3 6.8 2.1 4.5 0.8 3.4 7.0 10.5 5.5 3.5 2.1 6.6 2.0 3.6 2.6 28.9 4.5 6.7 118.4 5.9 8.9 9.9 4.3 4.4 4.1 32.3 7.1 4.0 8.1 5.2 7.8 5.4 6.3 3.2 0.4 13.0 4.4 1.1 14.0 12.9 11.0 2.2 124.0 3.2 4.0 6.8 8.9 12.2 7.6 6.9 26.1 14.6 21.3 21.4 2.5 1.0 46.1 87.5 1.6 4.5 16.2 1.6 1.5 1.9 11.4 14.8 50.2 5.1 12.9 2.7 52.5 12.2 1.5 12.9 148.6 9.3 1.2 4.4 5.2 7.4 4.9 2.0 2.1 6.2 4.8 11.7 63.4 2.7 12.3 11.3 6.5 5.4 11.1 15.0 122.1 2.7 88.0 2.2 16.8 62.4 57.0 0.3 61.3 0.6 37.2 0.1 0.3 14.5 19.6 0.1 0.1 133.6 0.5 77.6 1.2 0.0 28.7 5.2 6.2 6.5 7.9 6.0 7.0 11.3 6.8 10.5 6.7 9.9 8.1 1.4 0.0 5.6 1.6 31.6 0.3 0.1 0.4 1.8 0.8 1.0 0.9 0.4 0.0 0.2 0.0 0.0 0.5 0.3 0.2 0.0 0.2 0.0 0.4 0.4 1.9 0.0 6.3 4.1 0.2 0.7 1.2 0.5 0.8 18.3 0.2 7.1 0.8 55.7 0.0 3.5 0.3 0.0 51.1 2.3 0.4 0.6 38.3 1.8 3.7 45.4 0.3 2.1 0.5 0.5 0.0 0.7 1.2 38.3 0.2 0.2 0.1 0.1 0.6 0.0 1.8 0.4 3.0 1.9 0.7 0.3 1.0 2.2 0.3 0.8 0.1 DPYSL2 "CRMP2, DHPRP2, DRP-2, DRP2" ENSG00000092964 "Dihydropyrimidinase like 2" Q16555 8 26514031-26658178 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 549.9" "Cell type enhanced" "Detected in all" "Adipocytes: 362.9;Oligodendrocytes: 367.2" "Cancer enhanced" "Detected in all" "glioma: 89.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 65.8;intermediate monocyte: 74.5;myeloid DC: 71.2;non-classical monocyte: 48.8;plasmacytoid DC: 42.2" "Group enriched" "Detected in all" 5 "dendritic cells: 71.2;monocytes: 74.5" "Cell line enhanced" "Detected in many" "ASC diff: 263.7;Karpas-707: 279.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002381, CAB018719" Supported Supported "Plasma membrane,Cytosol" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "CAB018719: AB_2085366, HPA002381: AB_1847244" "unprognostic (2.88e-2)" "unprognostic (1.01e-2)" "unprognostic (9.51e-2)" "unprognostic (3.16e-3)" "unprognostic (8.23e-2)" "unprognostic (1.68e-2)" "unprognostic (1.51e-1)" "unprognostic (9.95e-3)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (1.79e-2)" "unprognostic (4.13e-2)" "unprognostic (5.58e-2)" "unprognostic (9.32e-3)" "unprognostic (1.23e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (5.41e-5)" 60.0 34.8 252.6 22.5 348.0 3.5 48.0 332.4 266.7 25.3 0.0 44.8 10.4 24.9 11.4 18.3 29.6 29.4 58.6 276.1 263.2 21.3 17.6 78.2 17.4 362.4 296.0 40.8 11.0 7.1 22.1 43.7 389.9 19.7 19.0 64.0 18.5 14.9 19.2 25.8 27.6 32.9 257.9 33.6 21.5 11.2 305.0 19.3 22.5 25.8 20.1 35.6 26.9 549.9 22.0 104.1 100.2 53.9 263.7 120.6 9.8 41.9 97.0 39.2 50.6 41.0 31.0 32.7 29.7 131.7 78.8 20.9 106.6 42.0 37.1 74.2 9.2 37.0 36.9 57.9 168.5 8.0 14.5 150.8 59.5 107.1 61.9 125.5 80.0 24.9 1.1 279.1 39.9 13.9 64.3 8.1 78.8 69.9 20.0 84.3 40.3 21.8 66.2 25.0 45.6 95.8 51.0 0.5 28.6 65.7 7.8 14.8 145.0 88.2 34.8 74.3 18.5 39.1 43.3 24.8 127.7 48.1 46.0 1.3 65.8 0.6 9.1 74.5 3.3 8.5 8.1 6.2 71.2 4.4 4.0 5.2 1.7 11.3 48.8 42.2 13.3 30.3 252.6 348.0 332.4 266.7 276.1 263.2 362.4 296.0 389.9 257.9 305.0 549.9 362.9 131.4 71.7 193.9 11.5 40.4 1.0 13.2 2.2 111.4 44.4 58.4 105.0 84.4 19.4 22.0 31.3 15.1 64.8 4.5 3.9 21.4 3.1 41.6 154.3 154.6 60.7 22.3 191.9 2.0 9.1 144.9 6.1 33.6 20.8 33.0 211.3 22.8 51.1 141.3 157.0 87.0 4.1 223.5 192.3 10.6 109.0 111.1 120.9 81.5 163.5 165.2 22.6 102.1 367.2 12.6 6.2 89.5 6.5 1.1 4.7 24.4 10.5 38.6 138.1 51.8 110.6 3.8 17.0 1.6 33.8 4.5 14.8 16.8 12.1 1.2 DRD4 ENSG00000069696 "Dopamine receptor D4" P21917 11 637269-640706 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Bipolar cells: 168.8;Cone photoreceptor cells: 87.6;Rod photoreceptor cells: 206.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062682 Uncertain "Plasma membrane,Centrosome" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" Centrosome "HPA062682: " "unprognostic (8.83e-2)" "unprognostic (2.99e-2)" "unprognostic (4.98e-4)" "unprognostic (3.81e-2)" "unprognostic (7.52e-2)" "unprognostic (7.89e-3)" "unprognostic (3.14e-2)" "unprognostic (2.96e-1)" "unprognostic (8.45e-2)" "unprognostic (5.07e-2)" "unprognostic (3.28e-1)" "unprognostic (8.59e-2)" "unprognostic (1.05e-4)" "unprognostic (1.26e-2)" "unprognostic (8.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.85e-1)" 0.9 0.8 0.5 0.0 0.6 0.0 0.8 1.3 0.6 2.5 0.1 1.9 0.0 1.6 0.0 1.1 2.5 0.0 1.1 0.4 0.0 1.3 1.5 1.3 0.0 0.6 0.2 3.5 1.5 0.0 4.2 0.0 0.5 2.3 0.0 0.0 0.5 0.0 1.0 1.5 1.1 0.0 0.1 0.6 0.8 2.5 0.3 0.0 1.8 0.0 0.0 1.7 1.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.5 0.6 1.3 0.6 0.4 0.0 0.6 0.2 0.5 0.1 0.3 0.6 0.5 0.0 0.5 4.2 0.2 0.0 0.3 0.2 0.0 168.8 0.3 0.4 1.7 0.0 0.1 1.8 87.6 0.6 8.6 0.8 0.0 0.1 0.7 0.3 0.4 1.5 0.0 0.0 0.8 0.4 0.3 0.5 2.0 0.7 0.0 1.5 0.0 0.1 0.2 6.7 1.2 1.3 0.0 0.3 0.3 0.2 0.6 0.9 0.0 0.0 0.1 26.0 0.0 0.0 2.6 0.4 0.2 0.7 0.1 1.1 8.3 1.9 0.1 206.9 0.0 0.8 0.6 1.2 2.6 0.8 0.4 0.1 0.1 0.5 1.3 0.3 DSC2 "CDHF2, DSC3" ENSG00000134755 "Desmocollin 2" Q02487 18 31058840-31102522 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 164.0;vagina: 97.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 384.0;Paneth cells: 324.8;Squamous epithelial cells: 705.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 48.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 28.9;neutrophil: 8.1" "Lineage enriched" "Detected in many" 14 "granulocytes: 28.9" "Cell line enhanced" "Detected in many" "BEWO: 37.6;CAPAN-2: 48.3;HaCaT: 71.1;hTCEpi: 76.0;OE19: 60.7;SK-BR-3: 44.4;SuSa: 43.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA011911, HPA012615" Enhanced Supported "Plasma membrane,Cytosol" NA NA 24000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" Cytosol "HPA011911: AB_1847618, HPA012615: AB_1847619" "unprognostic (3.28e-2)" "unprognostic (3.20e-1)" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (1.90e-1)" "unprognostic (3.04e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (7.66e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-3)" "unprognostic (2.10e-1)" "unprognostic (1.43e-3)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (3.01e-4)" 5.5 1.8 1.3 12.7 1.4 0.7 22.2 1.3 1.6 59.2 1.9 50.5 41.6 1.5 5.9 164.0 6.1 3.7 10.6 1.2 2.0 5.9 7.3 7.9 3.7 2.6 1.5 0.6 10.5 27.0 0.5 21.3 2.2 15.8 44.5 1.0 46.8 1.0 0.3 11.9 42.9 4.0 1.8 3.0 43.2 0.8 1.6 6.6 4.0 3.1 62.2 3.6 97.4 2.3 18.1 1.9 2.9 0.0 0.0 0.0 37.6 0.0 0.0 0.0 0.0 9.8 48.3 0.0 0.7 0.0 0.9 71.1 11.8 4.9 0.0 0.0 6.9 27.1 8.4 16.9 0.3 0.2 0.5 0.4 76.0 0.0 7.3 6.1 0.0 0.0 13.4 0.0 0.0 14.7 0.0 1.1 11.3 60.7 17.4 13.2 0.0 0.2 0.1 0.7 0.0 0.1 0.0 44.4 0.0 43.4 12.2 18.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 28.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.1 0.0 0.0 0.4 1.3 1.4 1.3 1.6 1.2 2.0 2.6 1.5 2.2 1.8 1.6 2.3 25.1 28.9 5.6 3.3 1.0 83.7 44.5 16.4 67.7 0.8 75.3 65.7 33.8 32.9 11.1 7.3 0.0 100.8 1.0 384.0 0.0 83.5 0.1 19.1 4.0 6.7 69.4 0.4 3.3 33.2 186.6 5.9 47.4 43.8 0.0 2.7 8.2 16.0 24.8 0.0 1.5 83.1 20.3 48.8 29.3 0.2 0.3 35.3 14.2 4.7 25.2 11.2 0.0 2.0 0.2 155.7 324.8 0.7 0.3 140.6 118.2 9.7 3.8 0.7 0.0 1.2 3.0 0.1 1.3 705.6 55.0 83.9 2.0 0.3 114.0 76.1 DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453722-71686768 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 95.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Endothelial cells: 43.7;Excitatory neurons: 34.7;Hepatic stellate cells: 32.2;Kupffer cells: 27.1;Oligodendrocytes: 62.7;Syncytiotrophoblasts: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 7 "neutrophil: 27.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.0" "Group enriched" "Detected in many" 5 "hTERT-RPE1: 31.9;HUVEC TERT2: 85.5;LHCN-M2: 75.3;RH-30: 78.5;TIME: 58.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002510, HPA017071, HPA021945" Enhanced Supported "Plasma membrane,Centriolar satellite" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Centriolar satellite" "CAB002510: AB_442097, HPA017071: AB_1847927, HPA021945: AB_1847928" "unprognostic (1.04e-1)" "unprognostic (7.66e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (3.21e-1)" "unprognostic (2.93e-1)" "unprognostic (6.43e-2)" "unprognostic (4.88e-3)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-3)" 10.1 1.7 1.0 11.5 1.1 31.6 4.3 4.1 7.7 1.9 0.7 7.0 2.0 2.3 0.5 7.4 3.2 4.6 16.8 0.2 3.8 3.6 6.5 8.3 3.7 14.8 5.1 1.3 1.5 2.3 1.5 21.1 13.7 3.3 2.5 0.5 1.3 4.8 95.3 1.2 3.1 10.2 2.0 21.4 2.5 1.1 10.2 2.3 4.6 32.3 0.9 6.9 1.8 1.8 1.1 0.0 3.3 3.0 0.0 0.0 6.1 0.1 0.8 2.2 1.5 0.4 1.0 0.0 12.1 0.1 3.4 2.5 0.0 1.2 1.1 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.0 1.5 0.0 2.3 10.6 31.9 85.5 0.2 8.4 0.0 75.3 0.0 0.0 5.8 8.1 0.0 0.9 0.0 78.5 0.0 2.6 0.2 0.0 0.0 4.1 0.7 0.1 7.9 0.3 0.8 58.1 0.3 3.8 0.2 1.1 0.0 0.0 0.0 0.0 13.3 0.0 0.0 4.1 0.1 0.5 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 27.0 0.4 0.1 0.0 0.0 1.4 1.0 1.1 4.1 7.7 0.2 3.8 14.8 5.1 13.7 2.0 10.2 1.8 30.5 3.2 8.1 1.0 1.0 2.4 0.0 0.1 0.0 1.1 0.3 0.6 24.0 0.0 1.3 0.0 0.0 8.1 0.7 0.1 0.0 0.4 4.8 0.7 1.3 43.7 0.0 2.7 34.7 0.2 3.8 2.2 0.0 9.3 2.5 0.3 32.2 13.4 11.4 0.0 13.0 0.2 0.0 27.1 3.0 6.0 0.6 10.2 0.0 16.9 5.8 0.1 0.0 2.5 62.7 0.1 0.0 0.7 0.1 0.2 0.0 2.1 0.7 0.2 6.6 5.2 5.5 0.6 1.1 0.1 1.6 66.2 1.1 0.9 0.0 0.1 ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 235.8;Endothelial cells: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 122 "EFO-21: 172.1;HUVEC TERT2: 443.7;TIME: 330.9" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: AB_2732701" "unprognostic (5.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.69e-2)" "unprognostic (2.15e-3)" "unprognostic (3.95e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.83e-3)" "unprognostic (2.41e-3)" "unprognostic (1.36e-1)" "unprognostic (9.90e-2)" "unprognostic (2.91e-1)" 62.7 12.7 5.5 11.2 5.5 0.2 59.8 5.7 8.5 26.8 5.3 19.4 4.6 29.4 7.4 15.9 33.5 12.1 54.6 5.2 5.9 29.9 6.0 60.1 11.6 6.0 5.9 10.4 6.7 4.7 7.1 33.5 6.3 19.6 8.0 0.8 16.1 7.3 15.1 16.6 20.7 24.4 6.1 23.5 15.2 3.3 6.7 3.5 40.9 17.2 7.2 35.5 26.1 5.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 0.0 172.1 0.3 0.1 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 443.7 0.1 0.0 0.0 1.4 0.0 0.0 0.9 2.5 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 330.9 0.4 0.4 0.0 1.7 0.0 0.0 0.2 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.5 5.7 8.5 5.2 5.9 6.0 5.9 6.3 6.1 6.7 5.9 235.8 0.0 3.9 0.0 1.0 14.9 0.4 0.0 0.0 0.0 1.9 2.5 0.0 0.0 0.6 0.0 0.0 0.2 1.0 0.0 0.0 0.6 0.0 0.4 0.5 214.9 0.0 0.0 0.1 1.2 0.1 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.7 10.6 5.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.0 0.0 0.7 0.4 0.0 0.0 1.9 0.0 0.0 0.0 13.9 0.3 1.3 0.9 0.0 1.6 EDNRA "ET-A, ETA-R, hET-AR" ENSG00000151617 "Endothelin receptor type A" P25101 4 147480917-147544954 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 113.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 117.1;Leydig cells: 43.8;Peritubular cells: 68.1;Sertoli cells: 52.6;Smooth muscle cells: 108.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 9.4;ASC TERT1: 18.2;HHSteC: 9.3;LHCN-M2: 22.7;SH-SY5Y: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013774, CAB018957" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB018957: AB_2039838, HPA013774: AB_1847994" "unprognostic (3.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.78e-1)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (1.39e-1)" "unprognostic (3.20e-2)" "unprognostic (7.20e-2)" "unprognostic (2.75e-3)" "unprognostic (1.47e-2)" "unprognostic (1.34e-3)" "unprognostic (2.88e-1)" "prognostic unfavorable (1.50e-7)" "prognostic unfavorable (3.93e-4)" "unprognostic (6.20e-3)" "unprognostic (3.11e-2)" "unprognostic (2.53e-3)" 14.0 5.5 2.1 3.3 2.8 0.0 8.3 2.7 4.2 57.0 2.1 3.2 3.4 44.7 23.3 4.4 18.4 12.7 26.0 2.2 2.2 4.2 3.1 22.7 3.8 2.9 3.1 37.5 1.1 3.4 2.8 12.1 2.9 30.7 3.4 0.3 6.4 113.9 4.0 4.6 2.9 45.1 2.5 8.4 5.4 6.2 2.9 4.9 6.8 5.5 2.6 11.8 24.0 3.0 0.0 1.2 5.2 0.0 9.4 18.2 0.0 2.9 3.8 0.4 0.1 0.2 0.0 0.0 0.0 0.9 0.6 0.0 0.4 0.7 0.2 0.0 1.9 0.0 2.8 0.0 9.3 0.0 0.0 6.9 0.6 0.5 0.0 3.4 0.0 0.0 0.0 1.4 22.7 0.3 0.0 0.1 1.5 0.0 1.1 0.0 0.9 0.1 1.3 1.0 0.0 16.3 0.0 0.0 0.0 3.4 0.0 0.0 0.0 3.6 0.7 0.0 0.0 1.3 0.4 0.0 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.8 2.7 4.2 2.2 2.2 2.9 3.1 2.9 2.5 2.9 3.0 7.7 3.2 5.3 1.0 0.0 3.1 0.8 1.7 27.3 0.1 0.8 5.2 24.9 0.0 4.5 0.0 0.0 0.2 0.1 0.0 0.0 0.1 2.9 3.4 117.1 8.0 0.0 0.0 5.3 0.0 0.1 15.9 0.0 2.7 0.0 14.3 0.0 0.0 0.6 0.0 22.5 0.0 0.0 0.0 3.9 3.5 43.8 0.8 3.6 9.4 0.0 0.1 0.0 2.0 1.0 0.2 0.0 68.1 0.0 1.4 0.0 0.5 0.0 0.5 52.6 0.6 108.6 0.7 0.7 7.1 2.7 0.1 0.9 0.3 0.0 0.4 EDNRB "ETB, HSCR, HSCR2" ENSG00000136160 "Endothelin receptor type B" P24530 13 77895481-77975529 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Deafness, Disease variant, FDA approved drug targets, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 127.8" "Cell type enhanced" "Detected in many" "Adipocytes: 120.5;Astrocytes: 126.3;Hepatic stellate cells: 112.5;Melanocytes: 110.3;Muller glia cells: 116.2;Sertoli cells: 216.9;Skeletal myocytes: 81.3;Smooth muscle cells: 102.1" "Cancer enhanced" "Detected in all" "melanoma: 127.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 68.0;ASC diff: 50.5;SK-MEL-30: 66.0;U-266/70: 40.7;WM-115: 131.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017842, HPA027546" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Cytosol "CAB017842: , HPA027546: AB_2672327" "unprognostic (7.75e-2)" "unprognostic (6.73e-2)" "unprognostic (1.41e-3)" "unprognostic (2.59e-2)" "unprognostic (8.37e-2)" "unprognostic (2.45e-3)" "unprognostic (4.17e-3)" "unprognostic (5.43e-2)" "unprognostic (1.02e-1)" "unprognostic (1.38e-2)" "unprognostic (3.40e-2)" "unprognostic (3.01e-2)" "prognostic favorable (7.20e-5)" "unprognostic (1.59e-2)" "unprognostic (3.86e-2)" "unprognostic (4.58e-2)" "unprognostic (6.77e-3)" 58.8 41.2 34.7 19.5 50.8 0.9 39.8 44.6 26.1 18.7 6.7 13.0 20.0 13.1 3.7 8.2 14.1 14.9 28.1 27.5 51.6 33.0 50.9 51.2 10.4 76.2 66.0 4.7 11.4 15.3 9.6 127.8 47.9 25.3 13.2 17.9 27.0 6.9 11.3 12.5 21.9 12.9 97.2 16.8 10.6 2.3 64.9 4.0 31.8 18.8 4.7 23.6 15.5 78.7 5.7 0.0 68.0 0.0 50.5 2.0 1.0 0.0 0.1 0.0 0.0 25.9 0.0 0.0 2.6 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.3 0.3 0.0 0.0 3.5 0.0 0.2 13.2 0.0 0.0 0.0 0.1 0.6 0.0 0.2 0.2 1.7 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.5 0.1 0.0 66.0 8.9 0.0 0.3 0.3 0.6 0.1 0.0 0.4 40.7 24.9 0.1 1.2 0.0 131.8 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 34.7 50.8 44.6 26.1 27.5 51.6 76.2 66.0 47.9 97.2 64.9 78.7 120.5 12.8 51.0 126.3 0.2 14.8 1.0 0.0 1.2 5.8 1.2 2.8 10.8 0.0 2.5 0.0 6.2 14.7 0.3 0.1 0.0 0.0 2.9 2.9 20.7 73.3 0.0 0.0 1.3 0.0 13.9 51.1 1.1 35.9 6.3 2.1 112.5 1.1 13.4 0.0 1.6 0.0 0.0 18.7 10.6 2.2 79.9 5.2 110.3 6.5 0.1 116.2 0.0 48.2 0.9 0.1 0.0 2.6 0.1 2.6 0.0 0.1 1.5 4.4 216.9 81.3 102.1 0.4 2.1 0.2 7.2 5.7 1.6 2.5 0.0 1.5 EFNB1 "CFNS, Elk-L, EPLG2, LERK2" ENSG00000090776 "Ephrin B1" P98172 X 68829021-68842160 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 117.3;Granulosa cells: 134.5;Hepatic stellate cells: 143.5;Suprabasal keratinocytes: 120.5;Theca cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 97.0;hTCEpi: 74.1;PC-3: 70.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031489, HPA067188" Uncertain Supported "Plasma membrane" NA NA 1300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "CAB031489: AB_631414, HPA067188: AB_2685799" "unprognostic (2.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.04e-1)" "unprognostic (2.48e-2)" "unprognostic (8.05e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (1.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.76e-2)" "unprognostic (8.03e-2)" "unprognostic (1.72e-3)" "unprognostic (1.86e-2)" 47.0 23.7 9.3 8.2 9.5 2.3 41.2 8.7 11.8 27.1 8.7 27.6 19.1 19.4 10.7 32.0 19.6 18.3 32.5 9.1 8.9 44.0 11.6 41.6 4.3 9.4 9.1 14.3 7.6 16.5 10.3 25.4 8.9 19.8 13.2 1.2 11.2 16.2 9.1 52.5 20.6 8.8 9.6 26.1 18.1 6.3 9.7 5.6 19.6 9.5 4.8 25.9 27.9 9.3 10.4 5.3 41.9 15.6 21.7 13.4 21.9 8.7 9.5 3.8 2.8 4.8 19.0 2.5 56.7 3.3 5.0 54.3 40.0 97.0 2.1 4.3 10.2 2.6 2.3 8.5 20.0 1.9 21.3 25.0 74.1 9.4 42.4 3.4 29.3 5.3 2.8 0.2 3.3 8.5 4.2 2.0 29.0 63.5 70.9 18.6 4.4 16.6 15.9 36.1 15.6 7.5 6.7 2.0 2.6 31.7 1.6 3.6 49.7 7.2 8.9 19.6 3.3 0.1 2.3 2.5 3.6 11.3 4.7 0.0 0.6 0.3 0.4 1.7 0.3 0.3 0.4 0.4 3.5 0.2 0.3 0.2 0.1 0.7 1.1 0.5 0.2 0.5 9.3 9.5 8.7 11.8 9.1 8.9 9.4 9.1 8.9 9.6 9.7 9.3 81.1 3.2 1.1 2.6 3.2 117.3 66.2 60.7 93.4 3.3 3.6 11.2 8.2 20.0 12.8 22.0 0.0 11.4 5.9 59.4 0.0 16.4 0.4 2.6 7.6 42.4 8.4 2.7 1.0 15.6 75.9 20.5 21.4 4.5 4.5 134.5 143.5 4.8 12.4 1.7 1.0 27.6 8.2 9.1 23.8 1.3 27.4 8.6 21.4 2.8 5.9 12.5 2.1 0.5 0.6 46.3 52.6 8.2 2.3 40.2 28.6 5.7 2.8 1.3 13.1 8.7 12.5 2.0 3.8 76.2 120.5 11.2 4.7 116.2 29.8 93.6 EFR3A KIAA0143 ENSG00000132294 "EFR3 homolog A" Q14156 8 131904093-132013642 "Predicted intracellular proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 121.6" "Cell type enhanced" "Detected in all" "Bipolar cells: 358.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022859, HPA023092, HPA023402" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cytosol" "HPA022859: AB_1848029, HPA023092: AB_2293240, HPA023402: AB_1848031" "unprognostic (4.79e-2)" "unprognostic (6.54e-2)" "unprognostic (6.42e-2)" "unprognostic (4.37e-3)" "unprognostic (2.77e-1)" "unprognostic (3.44e-2)" "unprognostic (3.04e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-1)" "unprognostic (8.11e-2)" "unprognostic (5.89e-3)" "unprognostic (5.22e-2)" "unprognostic (3.46e-1)" "unprognostic (3.00e-1)" "unprognostic (3.29e-2)" "unprognostic (1.29e-1)" "unprognostic (2.21e-3)" 21.7 20.8 22.7 20.8 28.6 14.5 20.0 36.4 35.7 28.3 13.2 21.2 23.2 23.4 38.0 27.5 24.2 21.8 33.9 29.5 9.3 29.8 44.5 27.8 25.3 52.7 13.6 19.3 18.6 33.6 12.0 20.4 59.0 26.9 18.4 121.6 17.3 29.3 41.6 21.2 23.5 36.1 7.0 23.5 22.8 22.1 16.1 24.3 37.8 49.1 27.9 26.9 14.0 23.9 55.3 49.0 15.0 12.4 59.9 68.8 29.9 38.6 54.0 31.5 41.3 10.8 40.4 33.8 35.5 87.6 41.8 17.9 23.9 52.9 38.3 78.3 13.1 33.7 22.7 22.0 57.5 13.0 34.1 58.6 29.6 31.2 49.0 52.2 40.2 16.4 18.7 44.3 56.5 36.1 36.5 11.9 8.5 47.3 30.4 14.5 29.4 16.1 38.0 34.1 10.0 34.6 76.9 10.8 30.6 39.3 34.4 22.0 56.3 55.6 50.9 27.4 40.9 31.3 28.8 20.9 41.2 31.0 29.0 12.0 16.8 17.4 16.2 23.3 14.5 12.6 13.0 13.3 17.3 11.2 11.6 12.0 10.1 15.5 40.9 4.0 11.3 15.8 22.7 28.6 36.4 35.7 29.5 9.3 52.7 13.6 59.0 7.0 16.1 23.9 32.6 41.7 42.8 90.8 40.7 21.2 25.3 29.5 25.0 358.8 29.9 16.6 57.4 28.6 37.5 51.5 91.8 22.8 34.1 33.5 21.5 28.7 4.5 25.9 35.1 29.1 11.4 13.3 126.8 30.9 22.2 34.4 29.0 20.7 25.9 19.8 25.0 79.9 44.5 26.9 122.6 18.7 26.4 59.4 25.0 8.0 19.9 52.9 8.8 60.0 53.3 42.3 42.2 77.9 55.6 25.5 36.0 44.4 32.6 55.8 39.9 58.4 27.7 107.5 19.7 32.3 41.4 52.9 30.9 39.1 31.4 37.1 37.3 36.8 17.0 36.7 EFR3B "FLJ37871, KIAA0953" ENSG00000084710 "EFR3 homolog B" Q9Y2G0 2 25042076-25159135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.1;skeletal muscle: 20.0" "Cell type enhanced" "Detected in many" "Astrocytes: 127.0;Excitatory neurons: 58.5;Inhibitory neurons: 110.7;Late spermatids: 46.0;Microglial cells: 54.4;Oligodendrocytes: 51.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.3" "Cell line enhanced" "Detected in many" "AN3-CA: 10.3;BEWO: 12.0;SH-SY5Y: 10.7;SK-BR-3: 18.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038089, HPA071831" Uncertain Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 10: Brain - Neuronal signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments, Cytosol" "HPA038089: AB_10672618, HPA071831: " "unprognostic (9.31e-2)" "unprognostic (3.92e-1)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.44e-2)" "unprognostic (1.24e-3)" "unprognostic (3.82e-1)" "unprognostic (3.42e-1)" "unprognostic (1.32e-2)" "unprognostic (4.49e-6)" "unprognostic (4.83e-2)" "unprognostic (4.43e-2)" "unprognostic (1.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-1)" 0.8 1.6 23.0 0.6 53.1 0.3 0.5 22.4 29.5 0.5 0.0 1.1 0.4 0.7 5.1 0.3 0.6 0.5 4.5 51.7 19.0 1.3 0.2 2.5 0.3 45.3 24.0 0.8 0.4 3.9 9.3 1.7 47.5 0.5 0.6 11.0 0.3 0.8 20.0 0.6 0.5 1.2 9.8 3.4 0.9 2.5 27.7 0.3 3.4 3.8 0.2 0.5 0.4 12.1 0.2 8.3 9.5 10.3 0.5 0.1 12.0 1.0 0.2 0.5 0.1 6.7 0.4 0.1 0.6 1.4 3.3 0.6 7.5 0.0 0.1 1.6 1.8 1.6 0.3 0.6 0.0 0.1 0.8 0.1 0.0 2.3 0.1 0.7 0.3 0.2 0.1 0.4 0.2 0.9 0.2 0.5 1.9 0.1 6.6 0.8 9.1 0.3 0.1 0.3 4.0 10.7 1.2 18.0 5.9 5.3 0.9 0.1 0.5 0.5 2.7 4.1 2.0 0.7 0.9 0.1 7.3 0.1 1.9 1.3 0.1 0.3 0.2 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 23.0 53.1 22.4 29.5 51.7 19.0 45.3 24.0 47.5 9.8 27.7 12.1 3.1 28.9 1.1 127.0 0.0 0.0 0.8 0.0 0.0 9.9 0.3 1.0 9.7 0.0 0.0 9.2 22.9 0.1 0.1 0.7 0.0 0.3 20.6 1.3 0.3 6.7 3.6 0.0 58.5 0.8 0.2 1.0 0.0 0.3 0.0 1.1 2.9 0.0 0.9 5.0 110.7 0.1 0.0 0.0 0.3 46.0 1.2 0.1 0.0 54.4 0.0 22.0 0.0 19.6 51.2 0.7 0.0 2.6 0.1 0.6 0.5 0.1 0.0 10.7 0.0 1.6 1.4 2.4 2.2 0.0 0.1 0.1 0.1 0.2 0.3 0.4 EHD1 "FLJ42622, FLJ44618, H-PAST, HPAST1, PAST1" ENSG00000110047 "EH domain containing 1" Q9H4M9 11 64851642-64888296 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 151.6;testis: 159.9" "Group enriched" "Detected in all" 10 "Early spermatids: 1033.0;Late spermatids: 1950.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA066751, HPA067747" Approved Supported "Plasma membrane" NA NA 10000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713, HPA067747: AB_2685896" "unprognostic (1.51e-1)" "unprognostic (3.21e-1)" "unprognostic (6.35e-3)" "unprognostic (2.43e-1)" "unprognostic (1.62e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.81e-5)" "unprognostic (1.46e-3)" "unprognostic (9.10e-3)" "unprognostic (9.44e-2)" "unprognostic (2.11e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (6.37e-2)" "unprognostic (9.88e-2)" "unprognostic (2.74e-1)" "unprognostic (2.59e-2)" 39.7 25.4 21.5 59.7 26.6 151.6 21.8 38.6 32.6 26.2 18.2 32.3 33.8 28.1 8.4 26.0 27.0 25.0 39.3 24.9 26.8 31.2 22.0 44.7 65.6 32.7 28.2 13.6 11.1 8.9 7.0 35.4 29.9 18.8 14.5 3.0 16.6 20.9 32.1 34.4 38.5 28.3 31.0 74.4 29.3 159.9 30.5 28.9 19.3 31.5 50.3 55.3 23.0 33.4 109.4 74.1 26.2 28.9 31.2 50.2 15.4 108.2 97.4 89.5 51.8 96.5 66.2 142.0 37.8 129.9 76.5 86.6 27.3 108.9 34.5 89.5 15.2 94.8 37.1 49.1 36.8 30.9 24.6 22.8 22.9 138.7 43.2 40.6 89.8 27.6 39.6 243.8 68.7 57.8 62.5 51.4 17.5 27.5 95.9 24.8 83.5 49.9 84.5 35.7 18.6 16.6 60.8 109.3 48.6 29.5 149.2 21.8 127.9 39.6 35.4 106.0 52.6 100.2 48.5 112.1 103.3 40.1 22.0 18.0 13.9 99.6 39.0 16.1 39.2 24.0 27.3 33.8 7.2 18.2 16.2 23.1 57.1 25.4 33.7 8.7 31.8 30.7 21.5 26.6 38.6 32.6 24.9 26.8 32.7 28.2 29.9 31.0 30.5 33.4 31.2 76.9 30.3 4.2 46.0 67.3 52.8 39.4 17.6 3.8 28.8 24.8 29.2 18.6 22.9 14.7 2.1 88.6 76.5 75.9 7.9 29.4 1033.0 41.9 24.4 29.3 6.6 19.8 1.7 40.8 24.5 32.4 25.5 54.9 93.8 37.2 10.4 10.9 32.2 5.0 3.5 27.7 12.2 37.4 61.0 1950.6 30.1 79.6 26.6 1.9 34.3 5.9 78.2 2.5 12.2 101.5 47.7 27.1 50.8 28.2 38.9 41.9 16.5 2.8 78.9 47.9 53.5 55.0 27.4 19.9 49.2 137.0 71.7 19.8 22.1 42.7 EHD2 PAST2 ENSG00000024422 "EH domain containing 2" Q9NZN4 19 47713422-47743134 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 161.9;Leydig cells: 99.1;Peritubular cells: 107.2;Sertoli cells: 236.7;Smooth muscle cells: 139.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 312.2;BJ: 238.5;fHDF/TERT166: 258.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047394, HPA049890, HPA049986, HPA066751" Approved Supported "Plasma membrane" NA NA 1500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "HPA047394: AB_2680026, HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713" "unprognostic (1.50e-1)" "unprognostic (2.11e-2)" "unprognostic (3.16e-3)" "unprognostic (1.54e-1)" "unprognostic (3.33e-2)" "unprognostic (5.42e-3)" "unprognostic (3.36e-2)" "unprognostic (1.33e-2)" "unprognostic (2.70e-3)" "prognostic unfavorable (8.75e-4)" "unprognostic (5.49e-3)" "unprognostic (9.50e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (6.59e-3)" "unprognostic (6.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.06e-3)" 195.0 59.9 18.4 32.8 17.6 0.4 133.9 16.5 21.2 110.3 11.9 116.1 14.3 119.9 13.2 53.5 75.4 31.2 85.9 15.9 17.1 24.4 14.4 102.8 9.1 23.3 19.3 68.3 28.2 6.2 12.6 50.3 20.0 62.2 14.7 3.0 34.2 51.1 39.6 54.7 54.5 79.6 17.2 40.3 56.3 11.2 24.1 5.1 49.5 28.2 8.3 112.3 88.8 15.8 62.7 142.7 0.1 1.7 312.2 236.0 0.2 238.5 114.0 86.0 70.0 9.3 31.2 0.0 0.3 258.6 20.3 78.1 1.5 126.5 51.9 0.1 0.8 8.4 78.4 0.7 197.0 0.0 16.6 230.1 109.5 72.5 70.6 113.7 168.4 0.7 26.6 0.2 91.7 11.4 13.3 0.7 1.8 9.2 25.9 1.4 10.0 0.2 69.5 2.9 0.1 0.8 212.5 8.2 6.2 19.1 20.2 4.3 192.6 128.0 27.8 112.5 52.2 0.2 0.2 0.2 119.3 3.3 27.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 18.4 17.6 16.5 21.2 15.9 17.1 23.3 19.3 20.0 17.2 24.1 15.8 161.9 60.9 20.6 10.7 0.3 20.3 29.4 31.0 12.5 5.5 7.3 10.8 11.6 10.0 22.5 5.5 0.0 1.1 0.8 0.1 0.0 21.2 0.6 3.4 60.5 75.4 0.0 8.6 4.0 14.1 1.6 55.8 5.1 4.5 2.5 24.7 48.9 3.1 1.9 0.0 0.9 0.0 2.0 1.3 8.8 4.3 99.1 1.6 8.8 7.5 0.6 1.8 0.0 3.5 0.3 31.1 0.0 107.2 0.1 28.8 0.0 0.1 5.5 0.8 236.7 24.8 139.4 0.9 3.0 15.8 13.5 1.5 1.5 27.2 0.0 33.4 ELAPOR1 "EIG121, KIAA1324, maba1" ENSG00000116299 "Endosome-lysosome associated apoptosis and autophagy regulator 1" Q6UXG2 1 109113679-109206781 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 156.7;salivary gland: 166.1;stomach 1: 88.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;dendritic cells: 1.2;Hofbauer cells: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 65.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 65.2" "Cell line enhanced" "Detected in some" "MCF7: 20.8;SCLC-21H: 16.8;SK-BR-3: 17.6;T-47d: 59.1;U-87 MG: 12.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029869, HPA070749" Enhanced Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 25: Pancreas - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "HPA029869: AB_10794320, HPA070749: AB_2686304" "unprognostic (2.10e-1)" "unprognostic (1.42e-2)" "unprognostic (1.99e-2)" "prognostic favorable (2.14e-7)" "unprognostic (4.18e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-3)" "prognostic favorable (5.69e-5)" "unprognostic (2.79e-2)" "prognostic favorable (2.16e-4)" "unprognostic (3.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.22e-16)" "unprognostic (2.46e-1)" "unprognostic (1.75e-1)" "unprognostic (5.64e-2)" "unprognostic (8.02e-2)" 0.8 3.2 3.6 4.1 4.4 0.5 56.7 0.0 4.9 70.1 0.0 28.3 45.5 12.8 9.7 1.6 23.9 5.6 0.2 4.4 13.2 0.1 0.2 5.1 2.5 0.2 0.1 0.1 156.7 9.2 32.9 0.2 0.7 48.6 27.8 0.4 166.1 0.3 0.0 3.9 35.3 1.1 0.0 0.8 88.2 18.3 10.0 0.8 9.0 0.1 1.9 0.4 0.1 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.8 0.5 0.2 0.1 0.2 0.0 0.0 0.5 0.6 0.7 1.3 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 1.0 0.0 0.0 0.5 20.8 0.2 0.3 0.5 0.0 0.1 0.1 0.3 1.1 0.1 0.0 16.8 0.4 0.1 17.6 0.0 0.1 59.1 0.0 0.4 0.0 2.1 0.2 0.2 1.3 3.6 0.0 12.4 0.0 0.1 0.0 0.1 0.0 4.6 0.0 7.6 0.4 7.5 3.2 0.0 0.1 3.3 1.5 65.2 0.5 0.0 0.0 9.8 2.2 3.6 4.4 0.0 4.9 4.4 13.2 0.2 0.1 0.7 0.0 10.0 1.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 ENO2 ENSG00000111674 "Enolase 2" P09104 12 6913745-6923698 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "retina: 1695.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 318.2;Cone photoreceptor cells: 312.8;Horizontal cells: 429.0;Rod photoreceptor cells: 787.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 9.9;MAIT T-cell: 11.3;memory B-cell: 6.8;memory CD4 T-cell: 13.1;memory CD8 T-cell: 11.4;naive B-cell: 4.4;naive CD4 T-cell: 8.2;naive CD8 T-cell: 8.6;neutrophil: 7.0;T-reg: 7.5" "Group enriched" "Detected in many" 7 "B-cells: 6.8;granulocytes: 7.0;T-cells: 13.1" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 537.4;U-87 MG: 398.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000063, HPA068284, HPA068721, CAB073539, CAB079023" Enhanced Supported Supported "Plasma membrane,Cytosol" NA NA 55000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "CAB000063: AB_2099322, CAB073539: , CAB079023: , HPA068284: , HPA068721: AB_2732119" "unprognostic (8.96e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.28e-1)" "unprognostic (7.95e-3)" "unprognostic (1.39e-2)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.48e-1)" "unprognostic (9.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "unprognostic (2.02e-2)" "prognostic unfavorable (7.89e-11)" "unprognostic (7.61e-2)" "unprognostic (3.06e-1)" "unprognostic (8.10e-3)" "unprognostic (1.24e-1)" 25.6 46.7 280.8 20.0 289.7 9.6 20.2 291.2 400.7 55.9 97.5 74.0 10.2 40.1 12.6 15.3 40.2 17.9 53.7 295.0 289.4 27.8 7.7 33.8 26.3 289.4 189.9 29.7 9.0 43.6 124.4 10.4 282.2 34.9 15.5 1695.6 13.8 34.4 7.4 19.3 37.1 35.0 164.3 26.4 30.4 9.6 259.0 26.7 42.0 6.4 24.4 57.4 44.1 306.2 74.3 45.3 16.2 0.5 23.7 26.0 1.5 56.5 37.3 82.0 125.9 8.6 5.8 103.9 9.5 24.3 108.8 11.0 173.0 15.4 116.1 211.9 16.6 141.0 47.7 60.3 17.4 8.3 161.2 13.0 0.7 61.1 11.5 537.4 17.5 137.9 9.5 1.1 56.3 10.3 66.9 8.8 84.9 31.7 27.2 75.0 13.9 22.9 38.5 9.8 128.3 94.0 14.3 1.0 96.3 76.4 4.5 3.9 20.9 69.4 73.7 95.7 73.0 73.3 79.5 15.4 398.4 0.3 15.2 2.1 0.0 0.2 9.9 0.0 11.3 6.8 13.1 11.4 0.1 4.4 8.2 8.6 7.0 0.4 0.3 1.2 7.5 6.1 280.8 289.7 291.2 400.7 295.0 289.4 289.4 189.9 282.2 164.3 259.0 306.2 3.2 35.3 27.4 54.2 11.2 6.2 2.3 45.2 1.8 318.2 5.2 4.3 16.1 1.5 17.2 12.9 312.8 0.3 7.5 0.3 0.0 17.0 0.5 9.6 2.1 9.9 23.9 7.0 96.2 1.8 1.1 8.3 2.0 2.7 67.2 1.0 5.3 0.2 1.7 429.0 89.4 0.5 18.3 0.6 6.9 0.3 5.6 5.9 12.4 25.3 3.5 146.1 0.0 23.6 31.5 9.3 1.2 9.8 9.2 2.5 0.1 0.2 32.2 787.2 13.1 8.1 20.2 1.5 2.5 1.1 2.3 0.3 17.1 0.3 0.4 2.2 ENO3 ENSG00000108515 "Enolase 3" P13929 17 4948092-4957131 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 26 "skeletal muscle: 14758.3;tongue: 10771.0" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 582.2;Skeletal myocytes: 248.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 263.8;HeLa: 120.0;HMC-1: 115.1;RH-30: 170.2;RPMI-8226: 96.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000793, HPA068284, HPA068721" Enhanced Supported "Plasma membrane,Cytosol" Yes No 86000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA000793: AB_1078742, HPA068284: , HPA068721: AB_2732119" "unprognostic (7.35e-2)" "unprognostic (5.25e-2)" "prognostic unfavorable (7.33e-4)" "unprognostic (1.57e-1)" "unprognostic (1.29e-1)" "unprognostic (5.86e-2)" "unprognostic (5.68e-2)" "unprognostic (2.08e-2)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (6.04e-3)" "unprognostic (2.21e-2)" "unprognostic (4.63e-2)" "unprognostic (5.34e-2)" "unprognostic (3.48e-1)" "unprognostic (2.15e-1)" "unprognostic (4.50e-2)" 7.8 5.5 3.8 15.6 3.9 20.4 8.0 7.1 4.3 6.6 5.0 8.0 20.1 7.2 7.1 173.8 7.4 2.6 499.8 3.5 3.7 10.3 108.0 8.6 13.0 4.3 5.0 6.0 5.5 4.0 7.9 6.3 4.6 47.3 3.0 5.0 116.8 3.1 14758.3 8.3 15.6 2.8 4.1 16.9 10.1 9.3 4.3 5.8 10.3 10771.0 4.9 5.6 5.0 4.9 12.0 25.5 11.3 10.7 9.1 2.2 27.6 21.0 2.7 1.5 1.3 12.8 8.1 21.9 25.8 1.9 3.5 15.4 3.8 1.9 1.0 263.8 24.3 21.9 120.0 18.9 3.7 6.8 115.1 14.4 3.8 2.1 4.1 9.8 1.4 24.8 10.2 39.0 4.9 6.6 7.9 26.5 14.8 3.3 10.6 34.6 170.2 96.9 3.1 7.9 7.1 27.1 13.6 11.4 14.7 7.6 10.2 7.0 6.5 12.1 21.3 5.4 16.0 27.6 16.8 18.2 6.7 20.8 12.2 31.4 28.5 50.4 36.8 41.5 24.8 24.5 30.8 34.4 37.6 20.1 20.0 32.2 34.4 34.9 47.6 29.9 43.2 83.6 3.8 3.9 7.1 4.3 3.5 3.7 4.3 5.0 4.6 4.1 4.3 4.9 1.2 0.0 1.8 2.3 2.7 2.0 1.2 2.1 4.0 6.6 3.0 3.0 582.2 0.0 2.2 5.5 4.2 5.4 3.2 2.9 0.0 1.5 1.8 0.9 1.6 7.3 0.0 3.8 0.2 0.8 3.8 17.3 4.6 2.2 8.2 2.4 2.2 56.2 4.5 3.3 0.2 2.2 2.0 3.5 6.7 3.7 0.3 4.3 1.8 0.0 78.3 1.9 4.1 1.0 0.5 1.8 1.9 0.4 2.3 1.2 6.6 9.5 0.3 2.5 6.6 248.4 55.8 7.9 7.5 2.1 1.8 3.3 4.5 1.1 2.6 0.8 ENOX1 "cCNOX, CNOX, FLJ10094, PIG38" ENSG00000120658 "Ecto-NOX disulfide-thiol exchanger 1" Q8TC92 13 43213518-43786908 "Predicted intracellular proteins" "Biological rhythms, Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.1" "Cell type enhanced" "Detected in many" "Astrocytes: 173.3;Early spermatids: 190.8;Excitatory neurons: 452.3;Inhibitory neurons: 692.0;Late spermatids: 264.8;Oligodendrocyte precursor cells: 167.9;Oligodendrocytes: 771.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 17.3;RH-30: 24.1;TIME: 17.8;U-2197: 17.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038355 Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA038355: AB_10673171" "unprognostic (9.64e-2)" "unprognostic (3.38e-3)" "unprognostic (1.64e-1)" "unprognostic (1.20e-3)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (2.88e-1)" "unprognostic (6.72e-3)" "unprognostic (2.60e-1)" "unprognostic (2.29e-3)" "unprognostic (1.32e-1)" "unprognostic (9.93e-2)" "unprognostic (1.32e-3)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (2.08e-3)" "unprognostic (1.42e-2)" 3.4 1.0 7.8 2.5 12.5 0.3 1.8 4.6 9.2 3.3 0.4 8.5 0.6 5.0 0.9 1.0 2.7 1.6 4.7 7.7 7.9 3.5 0.4 0.9 2.2 10.0 6.9 6.4 1.3 0.7 1.9 4.4 10.3 3.0 1.5 2.0 0.4 3.7 8.1 0.5 1.4 4.2 7.4 0.7 2.3 9.0 8.9 2.8 0.4 0.7 1.4 3.1 2.1 14.1 0.2 0.3 3.4 0.0 3.4 13.2 0.7 1.6 3.8 5.7 5.4 2.4 0.4 0.0 0.2 5.1 0.6 0.1 0.7 0.4 2.5 4.2 5.6 0.7 4.0 0.1 2.1 0.1 0.9 12.7 1.2 17.3 8.7 0.9 0.4 2.8 0.0 0.8 3.5 0.3 5.9 0.2 3.8 0.1 1.5 0.0 24.1 0.0 3.0 0.7 11.8 4.5 2.1 3.5 0.9 2.6 0.7 0.1 17.8 1.9 0.6 17.9 1.9 0.0 0.1 0.1 8.3 0.0 12.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 12.5 4.6 9.2 7.7 7.9 10.0 6.9 10.3 7.4 8.9 14.1 1.5 3.2 0.0 173.3 0.0 0.6 1.3 0.0 2.2 4.3 1.2 0.6 3.0 0.0 2.5 0.0 0.0 0.1 0.0 0.1 5.9 0.6 190.8 0.1 1.9 0.4 0.0 0.0 452.3 0.4 0.0 2.5 0.0 0.1 0.0 2.3 0.0 0.0 0.2 1.7 692.0 0.0 0.0 0.0 1.8 264.8 12.2 0.4 0.0 15.0 0.0 0.3 0.0 167.9 771.1 0.1 0.0 4.5 0.0 2.7 0.0 1.1 5.3 0.4 6.6 6.1 5.1 3.8 7.3 0.3 0.3 0.3 0.1 12.3 0.0 0.5 ENOX2 "APK1, COVA1, tNOX" ENSG00000165675 "Ecto-NOX disulfide-thiol exchanger 2" Q16206 X 130622325-130903317 "Predicted intracellular proteins" "Biological rhythms, Electron transport, Growth regulation, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 51.3;Oligodendrocytes: 132.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000514, HPA003027" Uncertain Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Plasma membrane" "HPA000514: AB_1078558, HPA003027: " "unprognostic (1.34e-2)" "unprognostic (7.02e-2)" "unprognostic (9.75e-2)" "unprognostic (1.08e-1)" "unprognostic (1.94e-1)" "unprognostic (2.60e-1)" "unprognostic (4.07e-2)" "unprognostic (6.07e-2)" "unprognostic (6.27e-3)" "unprognostic (5.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.09e-5)" "unprognostic (6.42e-2)" "unprognostic (4.60e-2)" "unprognostic (3.02e-1)" "unprognostic (1.38e-1)" 6.4 7.6 6.4 5.6 9.2 3.3 6.4 5.5 6.9 6.9 5.0 4.9 4.1 8.8 5.4 7.2 7.6 6.6 10.8 6.1 8.0 4.3 5.4 5.1 8.2 7.5 6.7 7.9 3.8 7.8 1.7 5.9 6.4 6.1 5.3 2.8 4.6 8.0 6.7 4.4 4.7 8.2 6.2 7.3 5.6 5.9 7.6 8.6 6.3 8.3 9.5 6.9 3.0 9.2 15.7 12.9 16.2 7.4 15.3 13.2 7.3 12.6 15.3 8.5 5.3 6.0 12.9 11.3 30.1 11.6 11.4 10.9 11.4 13.0 10.7 15.3 12.1 24.6 7.4 6.6 10.6 20.2 16.6 10.7 19.3 10.1 11.3 4.0 12.8 9.9 17.1 8.6 7.0 21.4 13.2 3.7 9.0 20.8 16.0 8.7 10.4 12.9 10.0 10.5 5.5 9.6 12.2 7.2 17.0 6.1 4.6 10.1 10.5 8.3 4.9 13.2 26.4 9.2 4.9 7.6 23.6 19.2 13.8 7.0 11.1 12.9 9.4 14.1 9.6 11.7 10.5 9.7 10.8 11.9 11.2 9.7 1.8 10.8 7.7 5.8 12.4 9.3 6.4 9.2 5.5 6.9 6.1 8.0 7.5 6.7 6.4 6.2 7.6 9.2 11.8 3.2 7.4 15.0 11.5 4.2 6.9 5.1 19.4 4.4 8.1 5.3 13.0 5.7 7.5 3.7 0.0 6.2 7.9 4.9 7.9 8.0 1.0 8.3 13.3 8.6 4.8 11.6 18.7 9.3 5.5 9.7 10.7 5.4 6.3 7.4 7.5 12.3 6.9 3.3 31.2 6.7 14.2 21.3 7.7 2.2 5.6 12.6 8.8 23.4 18.4 4.3 19.6 51.3 132.2 10.1 2.6 6.4 11.9 6.4 4.5 8.4 13.1 8.3 6.6 11.6 9.5 11.4 10.6 13.8 4.8 7.3 11.1 7.6 5.7 5.7 EPB41 "4.1R, EL1" ENSG00000159023 "Erythrocyte membrane protein band 4.1" P11171 1 28887091-29120046 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Cell division, Mitosis, Transport" "Actin-binding, Calmodulin-binding" "Elliptocytosis, Hereditary hemolytic anemia, Pyropoikilocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 80.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 151.6;Cone photoreceptor cells: 137.6;Erythroid cells: 187.1;Rod photoreceptor cells: 171.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 42.2" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 136.3;K-562: 136.5" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "cerebellum: 105.6" "HPA028076, HPA028096, HPA028412, HPA028414" Supported Supported "Nuclear bodies,Plasma membrane,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes No 1100000 "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cell Junctions" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA028076: AB_2672476, HPA028096: , HPA028412: AB_2672592, HPA028414: AB_10601366" "unprognostic (2.16e-1)" "unprognostic (1.96e-1)" "unprognostic (8.92e-3)" "prognostic unfavorable (4.58e-4)" "unprognostic (5.00e-2)" "prognostic favorable (5.87e-4)" "unprognostic (5.01e-3)" "unprognostic (5.40e-3)" "unprognostic (2.52e-2)" "unprognostic (6.65e-2)" "unprognostic (7.81e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (2.66e-2)" "unprognostic (2.42e-1)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" 11.0 10.2 1.8 21.9 18.3 63.3 14.1 42.2 6.0 14.5 4.9 23.6 17.7 10.2 5.3 16.6 6.3 15.0 9.7 1.2 4.7 12.7 21.7 15.1 37.4 8.2 5.6 16.3 18.8 15.5 4.7 7.2 8.5 15.0 23.1 80.0 19.1 9.1 15.9 15.3 23.3 9.9 3.5 22.9 27.0 10.4 4.7 69.0 15.2 13.8 37.0 15.5 1.9 3.0 27.0 6.9 62.3 29.4 5.2 0.8 19.5 6.9 10.1 8.4 10.5 16.8 31.2 49.1 17.2 9.2 13.5 11.9 78.7 6.6 8.6 86.4 23.8 136.3 19.7 28.6 10.1 45.8 88.2 1.7 18.4 8.2 13.8 19.9 14.1 73.5 136.5 36.2 0.1 8.8 72.3 30.4 62.0 44.1 10.0 110.9 28.2 68.3 7.7 33.3 78.0 60.5 19.7 19.2 43.3 21.7 14.7 18.2 1.2 0.3 13.3 12.9 13.4 52.5 72.4 85.2 12.1 47.8 6.8 33.3 3.2 21.4 12.9 1.1 15.4 17.2 18.3 14.1 4.4 13.6 22.1 12.7 44.2 10.9 1.5 4.4 28.9 15.3 1.8 18.3 42.2 6.0 1.2 4.7 8.2 5.6 8.5 3.5 4.7 3.0 25.3 19.2 71.7 20.2 58.2 10.5 8.6 7.8 15.4 151.6 20.0 12.2 21.5 20.0 16.8 16.5 137.6 2.4 75.3 26.5 17.6 17.1 16.4 11.3 4.1 15.1 41.6 187.1 76.3 18.7 4.2 7.9 29.6 29.1 24.1 24.9 17.5 30.0 7.1 21.9 61.7 29.0 16.2 23.7 9.0 22.7 2.1 32.4 0.0 78.7 29.3 15.7 85.5 7.5 4.8 28.6 20.3 2.2 46.7 12.2 32.8 13.4 15.2 171.4 13.1 2.8 8.5 39.3 55.7 14.9 16.8 4.1 71.6 4.2 33.0 12.6 EPB41L1 "4.1N, KIAA0338" ENSG00000088367 "Erythrocyte membrane protein band 4.1 like 1" Q9H4G0 20 36091504-36232799 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 156.4;Inhibitory neurons: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 10 "dendritic cells: 1.0" "Cell line enhanced" "Detected in many" "A549: 163.5;HaCaT: 237.9;OE19: 192.9;SK-BR-3: 185.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054104, HPA056817" Enhanced Supported "Plasma membrane" NA NA 33000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "HPA054104: AB_2682380, HPA056817: AB_2683244" "unprognostic (2.01e-2)" "unprognostic (7.77e-2)" "unprognostic (1.76e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (1.19e-1)" "unprognostic (2.31e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-2)" "unprognostic (3.87e-1)" "unprognostic (5.83e-3)" "prognostic unfavorable (9.30e-4)" "unprognostic (1.78e-1)" "prognostic favorable (4.39e-10)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" "unprognostic (2.47e-1)" "unprognostic (2.26e-2)" 55.1 122.1 68.6 8.1 73.8 0.4 25.7 66.0 97.2 37.7 0.0 31.2 13.8 27.9 31.0 46.3 45.3 40.3 21.3 64.7 81.7 64.7 8.9 30.1 4.4 101.5 80.3 41.8 29.3 37.0 21.1 21.8 94.0 26.9 20.9 39.5 56.6 42.6 12.0 14.2 16.7 27.2 53.0 8.1 64.2 18.3 75.0 4.5 24.8 15.4 14.0 40.7 31.7 79.9 53.5 163.5 57.7 21.5 36.8 22.8 53.8 16.8 37.7 35.1 27.9 108.7 93.7 3.0 26.4 52.7 71.7 237.9 26.7 19.6 26.2 0.5 14.9 0.4 52.7 107.6 11.3 0.2 19.4 19.9 9.4 32.9 2.7 44.7 8.6 13.0 2.7 41.5 30.5 34.2 1.8 0.9 21.4 192.9 49.9 2.6 16.0 66.3 30.5 84.6 20.1 24.5 74.9 185.6 6.4 43.9 45.8 2.4 7.3 40.9 43.0 20.8 3.7 50.3 19.0 0.6 71.2 0.2 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 68.6 73.8 66.0 97.2 64.7 81.7 101.5 80.3 94.0 53.0 75.0 79.9 14.5 16.0 22.1 27.7 0.4 2.9 5.0 11.1 30.7 31.9 12.8 9.4 8.5 28.6 16.5 47.8 156.4 1.5 0.8 23.8 19.6 22.2 2.9 10.6 8.7 9.2 15.5 0.0 56.8 10.8 0.5 11.0 50.4 7.5 52.5 13.3 10.0 3.7 6.9 32.0 75.7 6.0 4.1 1.3 2.2 2.7 15.8 6.0 3.6 3.7 0.0 22.7 0.0 24.6 73.1 31.6 15.7 42.2 2.1 5.1 8.0 37.1 21.9 8.7 32.9 6.8 35.1 4.6 7.1 43.2 1.7 1.1 0.8 7.1 13.2 18.0 EPCAM "17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1" ENSG00000119888 "Epithelial cell adhesion molecule" P16422 2 47345158-47387601 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 806.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2317.0;Ductal cells: 999.6;Intestinal goblet cells: 1378.2;Paneth cells: 2437.0;Proximal enterocytes: 2681.1;Undifferentiated cells: 1607.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 538.9;CACO-2: 680.9;CAPAN-2: 944.4;OE19: 911.8;RPTEC TERT1: 398.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB003809, HPA026761, CAB030012, CAB055098, HPA067463" Enhanced Supported "Plasma membrane" NA NA 22000 "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846" "unprognostic (6.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-2)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-2)" "unprognostic (3.40e-1)" "prognostic favorable (3.30e-4)" "unprognostic (5.27e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.04e-6)" "unprognostic (6.38e-3)" "unprognostic (1.28e-1)" "unprognostic (6.45e-3)" "unprognostic (6.08e-2)" 4.4 12.2 3.1 77.0 4.0 10.2 99.7 1.5 3.1 116.2 1.0 806.0 726.5 33.0 238.9 10.8 114.3 71.1 0.6 3.3 9.2 223.1 3.1 74.7 0.9 2.8 3.2 1.2 125.4 219.5 86.9 1.7 3.4 60.5 751.0 0.6 119.8 52.8 0.1 8.8 769.6 22.2 2.6 1.4 172.4 21.7 10.4 6.4 286.8 0.1 2.8 30.9 4.2 2.6 538.9 5.4 0.4 1.2 0.0 0.0 321.3 0.2 0.0 0.6 0.0 680.9 944.4 0.1 141.5 1.0 0.4 247.3 4.6 62.2 2.0 0.1 56.3 0.3 2.5 261.6 0.1 0.3 0.4 0.0 17.6 0.0 0.0 0.0 0.8 0.0 160.9 0.0 0.3 269.7 0.5 24.0 164.3 911.8 31.4 0.3 0.0 136.9 398.6 231.3 354.0 3.2 4.3 187.7 0.6 132.7 158.3 1.0 0.7 0.3 6.3 2.0 1.1 39.2 0.6 0.8 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.1 4.0 1.5 3.1 3.3 9.2 2.8 3.2 3.4 2.6 10.4 2.6 3.7 310.9 148.1 1.3 7.0 9.3 227.6 127.4 14.2 0.5 184.7 112.9 2.0 243.1 222.8 448.8 0.0 16.4 2.3 2317.0 76.3 999.6 8.6 434.7 35.3 5.8 498.1 23.1 1.1 402.8 6.5 6.3 150.3 445.3 32.5 11.8 1.4 0.6 2.9 0.0 0.4 1378.2 486.2 0.0 5.2 5.6 20.5 5.6 35.6 0.0 11.5 15.7 0.0 0.5 1.2 617.5 2437.0 18.8 1.8 257.9 2681.1 195.9 219.0 0.7 13.1 0.5 13.7 83.5 130.3 33.3 10.4 6.0 9.4 70.3 1607.7 230.7 EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156069 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 147.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 202.3;Glandular and luminal cells: 182.9;Squamous epithelial cells: 156.3;Suprabasal keratinocytes: 248.3;Urothelial cells: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "plasmacytoid DC: 9.4" "Lineage enriched" "Detected in single" 94 "dendritic cells: 9.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 201.1;PC-3: 229.0;U-251 MG: 242.1;WM-115: 258.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" NA Yes 12000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" 21.4 9.5 3.5 4.8 3.1 0.3 14.6 2.9 3.7 38.2 11.7 12.4 10.0 12.1 1.3 147.9 13.5 28.2 15.8 3.1 3.1 18.7 18.9 17.9 7.6 3.8 3.7 5.8 23.2 3.7 7.4 14.0 3.8 11.2 5.8 6.4 67.7 4.2 4.6 40.3 12.8 3.7 3.6 7.6 15.6 1.8 4.3 3.2 15.2 5.1 11.1 56.1 58.8 3.1 76.9 151.7 41.4 20.1 2.9 3.5 24.3 45.2 63.4 79.9 50.6 63.9 201.1 0.1 189.8 25.9 98.8 30.6 9.9 104.4 27.6 0.4 7.0 0.0 46.7 41.1 51.3 0.1 0.2 4.8 38.1 43.7 95.6 125.0 86.4 0.0 0.3 0.1 51.6 24.3 0.0 0.0 20.0 57.2 229.0 0.1 37.6 0.2 85.1 39.0 0.1 6.4 87.8 21.2 6.1 21.3 3.0 0.9 108.1 28.5 76.7 2.0 242.1 0.0 0.5 0.6 22.0 0.1 258.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 3.5 3.1 2.9 3.7 3.1 3.1 3.8 3.7 3.8 3.6 4.3 3.1 17.1 54.5 38.4 2.0 1.2 202.3 114.3 110.9 66.0 2.7 39.5 43.9 6.5 44.3 113.4 9.2 4.2 9.7 8.9 96.8 0.0 33.8 5.8 104.5 19.2 26.3 3.0 0.0 0.1 14.2 1.2 5.8 68.3 182.9 5.7 0.4 29.3 23.3 1.9 0.0 0.2 42.0 34.6 1.6 17.0 0.2 3.4 3.7 26.6 4.7 1.1 7.1 0.0 0.0 0.0 104.6 111.7 0.0 0.0 60.8 22.4 1.8 89.8 2.5 32.9 11.6 21.2 0.2 0.8 156.3 248.3 7.5 2.6 0.4 42.9 200.4 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 EPHB1 "EPHT2, Hek6" ENSG00000154928 "EPH receptor B1" P54762 3 134597801-135260467 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6" "Cell type enhanced" "Detected in many" "Astrocytes: 198.8;dendritic cells: 53.7;Early spermatids: 42.2;Excitatory neurons: 47.9;Inhibitory neurons: 44.3;Late spermatids: 41.2;Oligodendrocyte precursor cells: 77.9" "Cancer enriched" "Detected in many" 6 "glioma: 7.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 33 "neutrophil: 24.0;plasmacytoid DC: 23.3" "Group enriched" "Detected in many" 33 "dendritic cells: 23.3;granulocytes: 24.0" "Group enriched" "Detected in some" 5 "HDLM-2: 63.9;HMC-1: 35.5;RPTEC TERT1: 16.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067740 Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA067740: AB_2685895" "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (2.52e-1)" "unprognostic (1.41e-6)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.15e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (4.82e-2)" "unprognostic (1.78e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-4)" 1.0 0.6 4.7 0.8 18.7 0.7 3.2 40.6 12.8 1.8 0.0 3.2 1.4 2.2 0.9 1.9 1.3 1.7 0.3 7.0 5.1 1.3 1.6 0.3 1.9 5.0 14.4 0.7 0.3 0.2 1.0 0.2 5.5 1.7 0.5 4.2 2.2 2.7 4.9 4.8 0.7 0.7 0.9 1.9 0.6 10.8 12.0 0.7 7.0 10.3 1.7 1.5 1.0 4.2 0.0 0.0 8.4 0.1 0.2 0.0 0.0 6.6 0.1 0.3 0.1 0.1 0.0 1.1 1.6 3.4 0.6 0.1 5.5 0.0 1.2 63.9 0.8 4.8 0.0 0.0 0.0 0.0 35.5 0.1 0.0 0.1 0.0 0.3 0.2 0.5 0.0 0.3 4.7 0.2 0.0 0.3 2.4 1.2 0.1 0.0 0.9 0.2 16.5 0.0 1.1 0.2 0.0 0.1 0.0 1.1 0.1 0.7 0.5 1.1 3.4 0.7 7.9 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 23.3 0.0 0.2 4.7 18.7 40.6 12.8 7.0 5.1 5.0 14.4 5.5 0.9 12.0 4.2 1.9 0.0 0.0 198.8 1.0 3.7 0.0 0.0 0.0 1.9 0.8 12.3 1.6 0.0 0.0 0.0 10.4 0.0 53.7 0.0 0.0 0.8 42.2 0.1 0.5 2.8 0.0 0.0 47.9 0.4 0.1 0.4 0.0 0.1 0.0 3.3 0.4 7.0 0.4 0.0 44.3 0.0 0.0 0.0 0.8 41.2 0.6 0.8 1.8 8.4 0.1 16.9 0.0 77.9 5.6 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.5 0.0 3.3 0.8 0.5 1.6 0.0 5.8 0.0 0.2 3.0 0.3 0.2 EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.3" "Cell type enhanced" "Detected in many" "Ductal cells: 45.1;Enteroendocrine cells: 48.7;Intestinal goblet cells: 61.1;Oligodendrocytes: 76.3;Pancreatic endocrine cells: 63.7;Undifferentiated cells: 97.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 86.5;HUVEC TERT2: 74.2;TIME: 79.2;U-251 MG: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" No No 380000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: AB_2686360" "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favorable (4.98e-4)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" 3.1 1.6 2.1 9.2 3.7 0.5 1.6 4.1 4.2 2.5 0.0 22.6 21.0 1.8 1.9 0.6 4.4 3.7 3.3 2.2 4.3 3.8 0.4 1.8 2.9 5.7 4.5 10.6 3.9 6.1 2.9 4.0 4.8 1.9 23.3 2.9 1.5 3.0 0.2 0.9 21.8 3.3 5.0 2.4 1.7 1.8 5.4 1.2 7.3 0.3 1.7 4.4 1.0 8.2 43.4 17.2 17.2 27.7 1.6 1.5 0.0 10.0 0.5 27.3 5.7 6.3 16.6 0.6 20.2 4.0 86.5 39.6 10.8 52.8 7.7 0.1 4.1 0.0 1.9 0.1 16.5 0.0 4.3 5.3 17.5 48.7 0.3 25.4 74.2 2.4 1.8 0.1 5.7 6.4 1.1 0.3 4.0 49.0 11.2 5.3 18.0 0.8 14.7 4.0 18.0 19.3 17.4 0.7 0.2 1.5 1.1 0.5 79.2 11.5 29.6 29.4 69.5 0.0 0.2 0.1 21.8 0.9 0.5 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 3.7 4.1 4.2 2.2 4.3 5.7 4.5 4.8 5.0 5.4 8.2 0.4 3.2 0.0 5.5 0.3 0.8 1.7 20.5 0.0 15.4 0.1 0.1 1.3 7.2 8.6 0.0 0.0 0.5 0.1 24.3 0.0 45.1 2.6 1.0 0.8 1.2 48.7 0.0 34.1 8.0 2.8 5.0 1.1 2.4 0.0 0.5 0.4 0.4 9.6 6.7 32.3 61.1 6.1 7.6 1.4 0.8 0.9 7.2 0.0 21.5 0.7 18.4 0.0 5.5 76.3 63.7 12.6 0.7 0.3 2.3 5.5 0.2 1.7 1.8 0.0 0.6 2.1 0.5 3.5 0.0 0.4 1.1 0.3 0.2 97.2 1.1 EPN1 ENSG00000063245 "Epsin 1" Q9Y6I3 19 55675226-55709858 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 387.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 263.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009729, HPA061136, HPA071503" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB009729: AB_2277865, HPA061136: AB_2684436, HPA071503: " "unprognostic (6.93e-2)" "unprognostic (2.47e-1)" "unprognostic (5.30e-2)" "unprognostic (1.32e-1)" "unprognostic (7.94e-2)" "unprognostic (8.76e-2)" "unprognostic (1.23e-2)" "unprognostic (7.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.28e-1)" "unprognostic (6.16e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-2)" "unprognostic (3.86e-3)" "unprognostic (1.57e-1)" "unprognostic (2.78e-3)" "unprognostic (7.92e-3)" 57.1 75.3 63.1 27.3 61.2 22.1 53.0 30.3 82.2 51.1 14.8 73.1 88.7 47.8 9.2 80.5 48.7 14.3 148.6 65.2 31.5 85.2 137.1 50.5 19.3 37.8 38.5 76.2 104.3 22.3 51.1 17.4 31.1 64.8 16.2 8.9 50.9 20.0 156.1 71.0 80.4 11.0 27.9 72.8 152.6 80.8 40.0 11.6 49.0 35.3 11.2 50.1 54.5 47.1 95.5 128.8 31.5 64.8 35.6 33.8 64.6 69.3 39.0 48.2 48.0 54.1 58.7 58.1 46.1 55.6 42.5 71.5 27.7 52.9 17.4 20.4 263.2 42.8 67.4 65.3 48.9 27.8 39.3 43.9 45.6 41.7 30.1 34.7 46.4 40.7 64.7 48.0 32.2 53.6 44.4 45.2 72.3 71.4 179.6 29.5 42.8 103.2 36.8 55.3 45.2 109.9 64.1 68.8 48.0 21.7 51.6 95.7 78.4 133.0 63.8 48.4 101.3 52.2 50.9 41.7 97.9 55.0 67.5 1.4 1.8 2.3 0.6 2.2 0.4 1.0 0.6 0.6 1.1 0.8 0.6 0.6 2.1 0.3 3.6 1.7 0.9 1.5 63.1 61.2 30.3 82.2 65.2 31.5 37.8 38.5 31.1 27.9 40.0 47.1 62.6 3.2 20.4 9.8 44.2 31.4 29.0 25.9 44.3 33.3 32.7 25.8 15.5 55.8 17.9 44.1 66.7 46.1 28.1 227.7 119.3 57.1 63.2 39.5 37.5 46.1 45.0 35.3 7.8 88.5 80.8 37.2 145.2 45.9 10.8 87.0 83.9 106.1 62.9 28.6 7.8 115.6 22.4 136.5 21.4 169.4 47.5 55.4 23.2 6.5 40.8 33.6 28.8 4.5 8.9 106.5 167.7 53.0 57.7 37.6 387.2 81.8 20.9 41.3 13.1 41.2 34.6 50.2 62.7 46.6 27.4 52.3 26.3 48.2 132.5 39.2 EPOR ENSG00000187266 "Erythropoietin receptor" P19235 19 11377207-11384342 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 114.7;Hepatic stellate cells: 66.8;Hofbauer cells: 42.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077654 Supported "Nuclear speckles,Plasma membrane" "Intracellular and membrane" NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "Nuclear speckles" "HPA077654: " "unprognostic (9.13e-2)" "unprognostic (7.14e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (1.11e-1)" "unprognostic (3.70e-1)" "unprognostic (1.50e-2)" "unprognostic (5.60e-2)" "unprognostic (9.00e-2)" "prognostic favorable (3.17e-5)" "unprognostic (6.37e-3)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-1)" "unprognostic (7.48e-2)" "unprognostic (1.01e-3)" 6.5 17.5 6.0 1.4 6.3 22.4 5.0 6.7 8.2 7.1 7.7 2.7 1.4 3.3 13.6 1.3 6.7 2.3 9.7 6.3 6.0 21.6 10.7 6.4 2.2 6.1 6.1 3.1 11.8 23.2 8.2 8.0 6.4 4.6 1.7 3.3 3.3 7.3 2.3 1.6 2.3 1.8 6.0 11.9 7.8 1.8 6.2 1.7 30.2 1.5 1.6 3.1 3.7 6.3 3.7 1.2 3.6 4.2 5.3 3.4 2.1 2.2 7.0 3.6 4.5 1.3 1.4 2.5 4.0 4.1 5.0 0.9 2.8 1.4 4.1 2.1 1.6 14.3 1.3 2.1 3.8 2.9 5.5 2.4 0.5 4.8 3.3 8.5 8.5 5.3 12.5 12.0 4.1 3.3 2.7 3.5 1.9 2.0 9.6 7.2 6.3 5.6 3.4 1.9 1.4 11.0 1.5 2.0 6.4 3.7 3.6 4.9 3.5 1.9 2.6 6.6 2.1 6.0 4.7 2.8 10.5 2.9 2.1 9.3 3.7 3.0 1.7 4.6 3.6 2.0 3.4 2.5 2.1 1.2 3.7 2.2 10.2 0.8 7.3 0.1 3.3 2.4 6.0 6.3 6.7 8.2 6.3 6.0 6.1 6.1 6.4 6.0 6.2 6.3 6.1 19.2 18.8 24.8 11.5 2.3 4.0 2.0 2.8 3.8 3.6 6.1 6.5 5.7 3.1 20.2 0.0 2.2 5.2 1.3 3.9 2.2 0.8 9.9 6.8 13.5 8.4 114.7 2.2 3.3 12.2 9.8 15.3 13.9 26.6 1.2 66.8 3.5 42.4 1.7 3.0 3.5 2.0 17.0 4.0 0.6 2.8 15.4 8.8 7.5 4.6 7.9 11.3 1.0 1.6 3.1 0.4 4.1 3.8 1.8 0.2 1.0 2.9 2.5 19.7 3.8 18.5 5.1 7.7 1.6 1.0 3.0 9.6 2.6 1.8 1.2 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 254.3;Oligodendrocytes: 187.0;Paneth cells: 184.6;Proximal enterocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.4;neutrophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 116.4;OE19: 119.1;RT4: 89.7;SK-BR-3: 106.5;SK-MEL-30: 149.5;T-47d: 122.2;WM-115: 153.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 2.4 2.6 34.4 8.0 69.2 0.9 56.5 45.9 62.0 20.9 10.9 62.9 88.5 5.5 12.3 82.0 12.1 30.6 9.0 39.2 43.1 36.2 98.6 29.3 0.6 59.4 54.4 1.6 57.0 23.8 2.4 13.0 54.7 37.8 64.1 1.3 83.0 18.2 2.4 75.7 82.5 3.8 36.2 0.6 74.7 2.3 55.9 1.0 9.4 1.7 12.5 21.8 44.2 104.9 39.8 2.1 3.2 1.4 0.2 0.1 63.2 3.9 7.2 4.5 4.1 20.4 70.4 0.2 0.8 1.0 0.6 32.2 5.0 7.7 2.3 0.7 3.0 0.1 1.1 116.4 0.1 0.1 0.5 1.3 9.3 0.7 0.3 0.7 0.1 0.8 2.6 1.0 0.4 71.6 0.4 1.3 10.4 119.1 1.9 0.4 7.4 2.1 7.9 89.7 3.3 1.3 2.6 106.5 149.5 9.1 122.2 0.7 0.3 0.5 4.0 1.9 0.5 0.9 0.6 0.6 0.4 0.3 153.4 2.4 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 1.0 0.4 0.2 0.2 0.3 0.1 34.4 69.2 45.9 62.0 39.2 43.1 59.4 54.4 54.7 36.2 55.9 104.9 0.8 118.6 81.0 1.0 1.5 18.2 15.3 21.6 19.4 1.5 106.4 47.8 1.9 171.6 74.6 35.0 2.1 52.6 2.0 254.3 1.9 60.1 1.3 36.1 10.9 2.7 93.1 2.7 0.7 88.1 84.6 4.5 96.4 95.9 1.3 0.7 5.0 112.0 6.1 0.0 2.0 145.2 40.7 1.9 3.7 0.5 1.5 1.5 55.2 1.0 1.7 7.7 0.0 49.8 187.0 94.8 184.6 0.0 0.3 103.3 240.2 30.0 54.8 1.1 6.6 4.5 3.4 9.5 13.4 87.7 36.9 100.6 2.5 0.1 136.9 135.4 ERBIN "ERBB2IP, LAP2" ENSG00000112851 "Erbb2 interacting protein" Q96RT1 5 65926556-66082546 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 119.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;dendritic cells: 61.3;Endometrial ciliated cells: 62.3;Glandular and luminal cells: 101.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048606, HPA059863" Approved Supported "Nuclear speckles,Plasma membrane" NA NA 39000 "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles, Plasma membrane" "HPA048606: AB_2680461, HPA059863: AB_2684146" "unprognostic (4.34e-1)" "unprognostic (5.56e-2)" "unprognostic (9.88e-2)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (4.23e-3)" "unprognostic (1.74e-1)" "unprognostic (1.01e-1)" "unprognostic (1.46e-2)" "unprognostic (6.52e-2)" "unprognostic (5.45e-3)" "unprognostic (7.98e-2)" "unprognostic (5.62e-3)" "unprognostic (7.21e-3)" "unprognostic (3.08e-1)" "unprognostic (6.86e-2)" "unprognostic (7.81e-2)" 15.7 14.5 65.2 29.5 109.6 30.0 24.7 64.2 67.6 23.2 19.0 27.8 24.5 22.6 27.0 20.1 20.0 28.4 16.9 56.2 91.6 29.5 33.3 21.5 40.6 91.3 88.0 20.0 18.8 22.6 8.3 16.4 106.0 26.4 26.3 28.1 21.8 20.2 19.8 32.8 44.1 19.7 64.4 31.4 40.3 27.5 86.6 48.7 29.9 20.7 39.0 28.5 13.0 119.1 97.8 32.2 41.5 49.6 30.0 36.0 31.5 61.5 62.6 85.3 94.3 31.5 113.8 82.2 58.8 95.3 67.2 31.7 26.5 45.1 149.4 36.3 12.0 28.3 41.3 24.7 39.5 22.0 26.3 39.4 29.2 47.2 67.5 50.0 32.1 37.1 29.4 54.6 58.1 33.5 59.0 25.1 10.1 9.7 9.5 53.7 33.0 45.8 49.9 65.6 20.0 18.7 65.0 21.7 46.4 30.9 38.4 53.8 29.8 48.3 85.9 29.8 80.8 47.2 31.7 69.8 31.6 35.9 28.1 13.1 4.1 5.5 5.2 5.8 4.8 4.7 3.9 4.6 3.5 3.7 4.5 4.8 9.2 3.9 5.1 2.2 3.8 2.8 65.2 109.6 64.2 67.6 56.2 91.6 91.3 88.0 106.0 64.4 86.6 119.1 53.0 70.5 57.5 0.0 13.2 0.0 0.0 0.0 0.0 0.0 39.4 24.8 0.0 0.0 31.6 53.3 0.0 6.5 61.3 0.0 11.7 26.7 0.0 62.3 50.0 26.1 0.0 0.0 0.0 24.9 11.2 16.2 0.0 101.9 27.8 47.8 0.0 0.0 40.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 50.3 0.0 0.0 13.3 0.0 0.0 41.7 24.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 8.9 20.0 51.4 0.0 0.0 ERC1 "CAST2, ELKS, KIAA1081, MGC12974, RAB6IP2" ENSG00000082805 "ELKS/RAB6-interacting/CAST family member 1" Q8IUD2 12 990509-1495933 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 292.3;Horizontal cells: 185.1;Inhibitory neurons: 487.0;Microglial cells: 213.6;Oligodendrocyte precursor cells: 230.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019513, HPA019523, HPA024130" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Vesicles, Plasma membrane" "HPA019513: AB_1856012, HPA019523: AB_1856013, HPA024130: AB_1856014" "unprognostic (2.41e-1)" "unprognostic (4.00e-2)" "unprognostic (2.14e-1)" "unprognostic (5.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (5.50e-2)" "unprognostic (8.49e-2)" "unprognostic (2.53e-1)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (6.79e-2)" "unprognostic (3.75e-3)" "unprognostic (4.19e-2)" "unprognostic (3.01e-1)" "unprognostic (7.37e-2)" "prognostic unfavorable (7.01e-4)" 10.4 9.7 12.2 6.8 14.4 7.3 8.0 38.1 12.8 8.9 8.0 11.8 3.5 9.0 4.8 11.8 8.2 7.5 13.9 15.2 18.5 9.2 6.5 7.3 4.8 13.7 14.8 10.5 7.6 15.4 8.1 11.8 13.7 9.5 6.2 7.0 8.4 12.1 9.4 9.4 5.8 12.9 11.9 5.8 7.2 7.5 17.7 7.9 13.4 9.0 5.3 13.4 9.0 12.6 8.2 20.1 10.3 7.1 27.8 22.2 14.2 25.0 20.0 17.0 15.3 17.7 10.0 12.5 3.4 33.2 16.8 13.3 22.1 19.7 23.1 25.9 11.6 30.3 20.1 9.3 21.1 16.1 6.9 18.7 17.0 30.0 55.6 20.7 22.3 7.9 9.6 23.9 12.9 9.2 5.2 3.5 16.8 8.1 9.7 9.9 38.9 3.8 16.9 14.2 6.3 12.3 38.8 9.3 13.9 37.6 9.3 7.0 39.6 29.6 29.0 21.6 24.0 6.4 13.1 18.1 19.2 9.4 12.9 1.5 3.1 2.3 1.7 1.2 2.4 12.7 2.7 2.7 2.7 5.6 3.8 2.7 2.4 1.4 4.8 3.4 2.8 0.7 12.2 14.4 38.1 12.8 15.2 18.5 13.7 14.8 13.7 11.9 17.7 12.6 36.9 25.6 25.1 155.4 21.2 21.0 25.6 9.4 29.0 39.2 13.2 14.1 56.4 17.2 17.4 20.2 47.9 34.1 12.6 12.7 1.9 20.3 34.3 31.2 43.4 34.6 30.0 7.6 292.3 13.4 18.0 32.3 23.9 53.9 14.5 59.2 24.3 17.3 12.4 185.1 487.0 11.9 2.0 12.6 16.5 35.2 24.8 17.0 14.2 213.6 18.4 34.8 6.2 230.7 171.1 18.5 10.3 30.9 39.1 30.8 6.1 4.1 13.2 33.4 19.7 35.5 33.1 18.5 28.8 33.8 27.4 78.7 15.8 18.7 10.3 29.4 ESYT2 "CHR2SYT, FAM62B, KIAA1228" ENSG00000117868 "Extended synaptotagmin 2" A0FGR8 7 158730995-158830253 "Plasma proteins, Predicted membrane proteins, Transporters" "Endocytosis, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 185.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002132, HPA070823" Approved Approved "Plasma membrane,Cytosol" NA NA 24000 "Cluster 48: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA002132: AB_1078807, HPA070823: " "unprognostic (2.30e-1)" "unprognostic (1.06e-2)" "unprognostic (2.72e-2)" "unprognostic (2.84e-2)" "unprognostic (5.72e-2)" "unprognostic (5.43e-2)" "unprognostic (9.01e-2)" "unprognostic (9.94e-2)" "unprognostic (1.72e-1)" "unprognostic (8.71e-3)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.13e-1)" "unprognostic (7.54e-2)" "unprognostic (6.70e-2)" "unprognostic (4.58e-2)" "unprognostic (3.70e-3)" "prognostic unfavorable (2.81e-5)" 53.9 37.0 24.0 25.6 25.0 34.8 33.9 21.8 28.7 30.8 22.7 38.4 22.3 36.1 30.1 45.0 34.4 32.2 35.1 27.7 25.3 27.2 24.5 33.4 27.5 22.1 24.6 48.1 29.2 30.9 20.6 43.3 24.6 25.3 30.3 14.2 32.1 30.5 44.9 31.0 27.6 38.7 21.7 21.4 25.5 15.8 30.7 37.0 39.3 41.8 25.4 35.8 29.3 19.4 92.9 57.8 19.5 19.8 62.2 72.6 55.3 47.5 48.9 36.7 40.6 29.7 106.1 27.5 52.2 86.2 66.6 46.0 27.8 50.2 35.1 31.5 28.3 26.2 44.0 32.2 64.1 95.0 55.8 53.4 51.8 41.8 55.2 73.1 44.8 81.9 56.4 97.8 61.9 71.7 96.0 66.7 29.2 53.9 56.7 82.4 37.0 38.8 58.6 38.4 46.8 30.2 151.6 109.7 66.7 43.4 37.7 96.3 69.3 40.3 18.8 178.7 60.5 68.6 17.3 27.5 102.4 93.8 121.5 1.7 1.4 1.2 6.1 1.8 3.4 1.1 5.1 4.3 2.8 0.6 4.6 5.5 0.9 5.4 1.2 1.8 4.2 2.3 24.0 25.0 21.8 28.7 27.7 25.3 22.1 24.6 24.6 21.7 30.7 19.4 65.7 38.5 32.4 55.5 18.1 46.1 12.9 22.6 19.4 15.0 32.6 21.6 30.8 21.5 33.7 47.8 16.7 31.6 54.0 41.0 3.9 15.3 18.0 60.6 17.8 48.5 21.1 17.7 137.1 20.0 26.1 44.2 15.8 47.0 12.6 36.8 23.2 20.9 20.2 13.5 119.3 31.2 24.4 20.2 83.6 5.3 35.1 27.7 51.6 185.5 21.9 12.1 43.3 67.3 61.4 29.9 14.1 54.5 36.2 23.2 28.0 8.7 61.8 10.8 32.9 42.6 60.4 10.6 10.2 22.0 51.7 40.8 43.4 19.5 26.0 25.8 F2RL3 PAR4 ENSG00000127533 "F2R like thrombin or trypsin receptor 3" Q96RI0 19 16888999-16892606 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 19.0;lung: 33.4;thyroid gland: 19.2" "Cell type enriched" "Detected in some" 4 "Adipocytes: 110.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "HEL: 30.7;HMC-1: 11.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031401, HPA042340" Supported "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "HPA031401: , HPA042340: " "unprognostic (6.17e-2)" "unprognostic (1.08e-1)" "unprognostic (2.64e-2)" "unprognostic (3.83e-1)" "unprognostic (3.27e-1)" "unprognostic (8.31e-3)" "unprognostic (2.97e-1)" "unprognostic (3.28e-2)" "unprognostic (6.52e-2)" "unprognostic (2.60e-1)" "unprognostic (6.30e-2)" "unprognostic (3.00e-3)" "prognostic favorable (6.25e-4)" "unprognostic (2.37e-2)" "unprognostic (1.43e-1)" "unprognostic (3.53e-1)" "unprognostic (2.11e-2)" 19.0 2.6 0.7 1.5 0.7 1.3 18.0 1.9 0.7 1.1 1.2 4.3 1.5 1.6 1.6 1.5 1.5 2.8 5.6 0.6 0.7 9.8 0.5 33.4 2.3 0.5 0.6 0.8 9.3 1.1 2.7 1.0 0.5 1.4 1.3 1.2 1.2 0.5 3.2 3.1 4.9 1.0 0.0 1.3 5.0 1.7 1.2 0.4 19.2 0.6 0.9 1.9 1.2 1.3 0.3 0.3 0.8 0.4 0.1 0.2 0.9 0.4 0.1 0.2 0.2 0.5 0.8 0.6 0.6 0.3 0.3 0.6 0.2 0.3 0.3 0.4 0.4 30.7 1.3 0.5 0.2 0.3 11.6 0.0 0.1 0.3 0.2 0.4 0.9 0.6 2.5 1.1 0.2 0.5 0.4 2.9 0.4 0.4 0.3 0.3 0.2 1.0 0.3 0.6 0.5 0.3 0.3 0.2 0.1 0.7 0.6 2.0 1.2 0.6 0.6 0.4 0.3 0.5 0.4 0.6 0.3 0.5 0.4 3.3 0.9 0.7 0.9 0.4 0.8 1.6 1.0 0.8 0.3 1.8 1.4 1.3 2.2 1.8 0.6 1.7 0.8 1.4 0.7 0.7 1.9 0.7 0.6 0.7 0.5 0.6 0.5 0.0 1.2 1.3 110.4 0.0 1.1 0.0 0.3 0.4 0.3 0.3 0.0 0.0 0.3 0.3 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.9 27.5 0.0 0.8 0.0 0.5 0.0 2.7 0.0 0.2 7.0 0.3 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.3 1.0 0.4 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 2.0 0.6 0.0 0.1 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.1 0.4 0.5 0.1 0.3 0.2 0.3 FAM126A "DRCTNNB1A, HCC, HYCC1, hyccin" ENSG00000122591 "Family with sequence similarity 126 member A" Q9BYI3 7 22889371-23014130 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 133.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042873 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA042873: AB_2678207" "unprognostic (7.94e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (1.96e-1)" "unprognostic (7.38e-2)" "unprognostic (3.54e-4)" "unprognostic (1.35e-1)" "unprognostic (9.76e-3)" "unprognostic (1.30e-2)" "unprognostic (7.23e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (6.04e-7)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.87e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (9.03e-4)" 14.9 4.7 5.0 8.5 6.9 4.2 12.2 4.4 6.5 9.7 7.9 9.7 9.4 8.7 1.4 12.2 6.7 11.4 10.5 12.1 4.5 4.7 8.5 13.7 11.5 5.0 5.9 6.6 6.2 2.3 5.0 14.8 5.4 5.9 4.4 4.9 6.8 4.8 25.0 4.9 6.9 11.5 4.5 11.8 4.6 12.0 6.3 4.2 6.6 15.3 9.2 9.4 11.2 7.8 22.4 12.4 63.6 22.3 61.3 100.9 10.6 103.0 101.8 41.6 63.9 19.8 10.6 13.3 15.9 82.6 87.2 7.7 44.3 14.7 72.6 6.6 22.4 14.7 18.1 13.0 48.0 19.3 15.7 41.1 9.2 85.0 61.3 83.4 42.5 7.5 30.4 58.6 77.5 7.9 10.8 24.2 63.0 0.1 22.9 15.7 63.5 9.5 13.1 11.2 10.4 0.1 38.1 0.4 19.2 52.5 8.2 20.4 51.0 150.0 18.3 71.8 37.4 67.2 30.6 60.9 91.1 12.5 112.6 4.7 2.9 13.7 1.4 7.8 1.3 6.4 2.6 1.3 3.9 7.4 0.9 1.5 0.3 2.1 9.8 1.6 4.0 2.5 5.0 6.9 4.4 6.5 12.1 4.5 5.0 5.9 5.4 4.5 6.3 7.8 27.8 3.2 15.1 19.6 29.1 25.5 5.1 8.3 15.9 60.3 5.4 32.4 21.9 2.8 4.2 3.7 2.1 11.8 28.8 0.5 0.0 6.8 49.0 12.5 22.4 31.4 7.7 19.8 13.6 4.8 15.5 42.9 2.6 11.3 8.2 8.6 26.0 17.7 15.2 16.8 13.6 3.0 2.0 25.1 55.2 22.4 20.2 31.5 35.6 47.8 24.0 6.8 11.3 23.6 133.2 3.6 1.4 19.5 26.4 4.7 8.3 5.7 2.4 4.6 19.7 24.0 31.7 72.2 11.1 35.0 24.0 6.0 20.6 12.2 4.7 6.5 FAS "APO-1, APT1, CD95, FAS1, TNFRSF6" ENSG00000026103 "Fas cell surface death receptor" P25445 10 88990531-89017059 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis "Calmodulin-binding, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 114.7" "Group enriched" "Detected in all" 5 "granulocytes: 114.7;T-cells: 96.2" "Cell line enhanced" "Detected in many" "HDLM-2: 83.4;Karpas-707: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027444 Uncertain Supported "Nuclear bodies,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11900000 420000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nuclear bodies, Cytosol" "HPA027444: AB_10601378" "unprognostic (6.84e-2)" "unprognostic (2.88e-3)" "unprognostic (8.38e-3)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (9.56e-2)" "unprognostic (7.00e-2)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (7.70e-2)" "unprognostic (1.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.32e-2)" "unprognostic (4.95e-3)" "unprognostic (1.65e-1)" 14.1 26.3 3.6 17.0 3.6 20.8 10.9 2.9 4.7 12.7 2.8 16.4 7.0 12.8 10.3 10.8 14.8 15.7 7.5 3.6 3.7 7.2 23.3 21.7 18.9 4.6 3.1 20.1 3.7 2.7 3.7 10.4 4.0 8.9 23.3 3.3 6.5 9.3 2.3 9.4 9.2 15.0 3.5 11.2 4.4 2.6 3.9 14.4 7.3 2.6 15.6 12.9 10.2 4.3 22.7 8.2 5.4 13.9 37.0 51.3 0.0 51.8 50.2 1.7 9.1 0.1 23.4 4.7 19.0 52.1 9.6 4.0 1.0 44.8 3.2 83.4 8.7 0.4 5.2 14.7 31.6 3.4 1.6 69.2 38.7 31.4 66.0 24.5 4.7 17.8 0.0 109.0 44.0 1.4 6.4 3.4 0.6 0.2 1.8 1.4 0.5 5.0 60.7 7.3 0.4 0.2 7.7 0.0 0.8 7.0 13.9 1.0 9.5 15.8 9.0 15.2 12.3 45.3 5.3 0.4 11.8 10.2 4.5 43.1 9.4 30.9 9.9 12.3 13.8 7.5 27.6 19.6 11.5 4.0 3.1 10.0 114.7 3.1 22.1 0.2 96.2 12.8 3.6 3.6 2.9 4.7 3.6 3.7 4.6 3.1 4.0 3.5 3.9 4.3 10.3 57.7 13.8 40.1 12.8 45.9 109.7 53.1 39.9 0.0 5.5 9.5 3.5 12.8 27.5 9.2 0.0 0.4 16.3 24.9 0.0 6.3 11.3 9.2 22.3 8.9 8.4 9.5 8.8 4.3 0.2 35.4 8.6 15.5 3.8 4.9 2.2 19.3 5.5 1.7 2.8 14.4 8.2 7.0 31.7 4.9 19.0 17.7 12.4 17.8 20.9 14.5 10.3 8.0 0.7 6.5 8.7 13.9 32.2 46.0 15.6 14.4 26.3 0.7 6.6 26.8 29.1 11.3 1.1 28.5 43.9 0.4 48.4 11.8 24.4 30.0 FBLN2 ENSG00000163520 "Fibulin 2" P98095 3 13549125-13638422 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 292.8" "Cell type enhanced" "Detected in many" "Adipocytes: 92.7;Endometrial stromal cells: 84.4;Fibroblasts: 458.4;Leydig cells: 170.9;Peritubular cells: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 6.7;naive CD8 T-cell: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 384.0;fHDF/TERT166: 264.3;HMC-1: 311.6;HSkMC: 221.9;U-2197: 139.2" "Group enriched" "Detected in many" 4 "olfactory bulb: 12.4;white matter: 3.1" "Low region specificity" "Detected in all" "HPA001934, CAB018622" Enhanced Supported "Plasma membrane" "Secreted to extracellular matrix" NA NA 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB018622: AB_2294196, HPA001934: AB_1078827" "unprognostic (1.19e-1)" "unprognostic (7.76e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (2.82e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.17e-4)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" 157.3 7.6 5.9 12.7 7.7 1.0 97.3 5.2 9.0 63.4 6.4 32.7 6.2 31.1 3.2 42.4 26.8 46.2 292.8 7.0 4.9 8.7 3.7 29.2 8.4 5.3 5.3 5.8 8.6 3.0 2.3 80.3 4.8 29.1 11.8 0.6 39.4 8.8 47.7 72.5 19.8 14.7 4.1 6.0 22.3 46.7 6.9 14.2 63.7 48.9 5.6 79.6 56.7 4.4 0.0 1.4 50.9 0.0 384.0 51.7 23.8 124.9 98.2 122.4 80.4 8.1 0.3 0.0 5.9 264.3 0.2 0.2 0.0 0.5 22.9 0.1 0.1 100.7 1.9 0.0 26.0 0.2 311.6 221.9 2.0 19.3 0.0 0.2 0.0 8.6 0.8 0.9 0.6 0.3 5.2 0.6 12.2 0.0 0.7 0.2 0.0 0.5 0.9 0.1 3.0 2.4 0.5 90.3 0.1 13.6 0.2 0.3 0.1 0.1 0.1 139.2 0.1 0.2 0.0 0.0 1.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.2 6.7 1.3 0.0 3.7 0.0 0.2 0.0 0.5 0.0 0.9 5.9 7.7 5.2 9.0 7.0 4.9 5.3 5.3 4.8 4.1 6.9 4.4 92.7 0.0 1.5 1.6 3.6 30.8 0.8 10.5 2.2 0.0 1.7 1.9 8.8 0.0 12.3 7.3 2.1 7.8 1.9 0.1 0.0 0.0 3.8 2.9 84.4 43.8 0.0 1.7 0.6 0.2 4.8 458.4 6.1 2.7 23.6 0.6 47.8 0.4 3.6 0.0 0.6 0.0 0.0 1.9 49.8 12.1 170.9 4.5 39.2 26.2 0.3 1.2 0.0 30.7 0.3 0.3 0.0 227.2 1.6 1.2 2.7 0.1 1.4 0.4 13.1 29.7 26.4 3.4 13.5 2.0 28.8 6.2 5.3 0.2 0.0 1.1 FBXL2 "FBL2, FBL3" ENSG00000153558 "F-box and leucine rich repeat protein 2" Q9UKC9 3 33277025-33403662 "Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 48.8;Excitatory neurons: 125.0;Inhibitory neurons: 92.8;Late spermatids: 50.7;Oligodendrocyte precursor cells: 55.8;Oligodendrocytes: 49.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 5.7;LHCN-M2: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003240, HPA061783" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003240: , HPA061783: AB_2684605" "unprognostic (5.73e-2)" "unprognostic (4.47e-2)" "unprognostic (7.92e-2)" "unprognostic (7.21e-2)" "unprognostic (3.68e-1)" "unprognostic (1.59e-1)" "unprognostic (1.10e-2)" "unprognostic (2.09e-1)" "unprognostic (3.16e-1)" "unprognostic (2.00e-1)" "unprognostic (4.31e-2)" "unprognostic (1.06e-1)" "prognostic favorable (3.35e-4)" "unprognostic (3.30e-3)" "unprognostic (9.72e-2)" "unprognostic (4.28e-2)" "unprognostic (5.90e-2)" 0.9 1.3 3.6 0.4 3.8 0.3 1.0 2.2 4.0 1.1 4.2 1.1 0.7 1.0 2.1 0.4 1.5 0.6 0.9 3.5 3.7 1.4 0.2 1.2 0.3 2.9 2.6 1.4 1.1 2.7 2.7 1.4 3.0 1.0 0.2 4.2 0.8 1.6 0.2 0.6 0.5 0.8 1.6 0.5 0.8 1.1 3.3 0.2 2.3 0.0 0.2 0.8 0.9 2.7 2.7 0.7 1.0 1.0 1.5 2.4 0.4 2.0 1.6 1.8 2.6 0.5 3.1 0.1 0.6 1.3 0.8 0.5 0.9 2.1 1.2 0.2 1.1 0.4 2.3 0.5 1.8 0.2 0.4 0.9 1.6 1.1 0.8 5.7 3.3 1.9 0.5 0.2 6.2 0.2 0.5 0.3 0.7 0.3 0.6 0.1 0.6 0.1 4.6 0.7 1.1 1.1 0.9 0.5 0.8 1.7 1.3 0.7 2.5 0.8 0.7 0.6 1.1 0.2 0.1 0.1 0.8 0.2 0.6 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.0 3.6 3.8 2.2 4.0 3.5 3.7 2.9 2.6 3.0 1.6 3.3 2.7 2.7 3.2 7.3 22.2 1.0 1.1 7.6 5.6 1.8 15.3 3.0 3.7 2.4 2.8 4.8 5.5 25.0 0.5 0.4 0.1 3.9 3.9 48.8 18.8 3.6 3.8 0.0 0.0 125.0 0.4 1.5 5.0 5.6 6.2 0.0 6.2 2.2 0.1 0.5 18.5 92.8 0.3 8.2 0.8 2.4 50.7 1.5 0.5 1.8 22.5 0.1 6.6 0.0 55.8 49.6 4.2 0.1 4.1 0.3 4.2 0.2 3.2 16.5 17.7 6.6 3.6 3.9 21.3 8.6 0.7 1.1 0.7 1.5 3.5 0.1 3.8 FBXO38 "Fbx38, FLJ13962, MOKA, SP329" ENSG00000145868 "F-box protein 38" Q6PIJ6 5 148383935-148442836 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034821, HPA041444" Approved Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA034821: AB_10669897, HPA041444: AB_2677484" "unprognostic (7.72e-2)" "unprognostic (5.75e-3)" "unprognostic (1.95e-2)" "unprognostic (1.67e-1)" "unprognostic (2.21e-1)" "unprognostic (2.70e-2)" "unprognostic (7.06e-2)" "unprognostic (5.43e-3)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (2.03e-1)" "unprognostic (6.29e-2)" "unprognostic (2.21e-3)" "unprognostic (1.31e-3)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" "unprognostic (4.70e-3)" 12.8 11.5 7.3 12.9 8.4 9.8 13.9 8.1 9.9 14.1 8.2 12.5 9.6 12.5 11.1 10.5 10.0 11.5 17.4 7.0 7.7 12.9 18.0 14.5 14.6 8.0 7.6 12.3 9.5 18.5 10.2 13.8 8.0 14.6 13.0 11.0 11.5 12.0 18.7 12.2 11.6 12.3 7.5 14.4 12.5 12.4 7.8 20.2 12.2 16.8 15.6 13.8 11.2 9.9 12.6 13.2 20.1 14.7 22.1 24.6 10.4 16.1 30.7 22.4 30.5 19.6 15.1 18.2 15.5 26.2 23.6 17.2 21.2 20.3 26.8 20.1 13.6 10.8 19.0 13.3 21.9 29.6 17.0 24.0 17.1 21.6 21.1 24.0 30.7 16.6 12.2 19.1 22.3 5.1 18.8 13.8 9.4 13.9 19.8 16.6 29.3 18.4 21.7 14.5 17.9 17.3 21.4 14.2 21.2 17.1 15.0 21.2 20.2 20.4 7.3 10.8 18.2 23.3 25.1 15.3 20.3 16.6 15.8 15.1 6.1 9.1 5.0 8.0 5.5 4.9 4.7 5.0 7.5 3.8 4.8 6.2 11.2 7.7 15.2 3.7 7.4 4.9 7.3 8.4 8.1 9.9 7.0 7.7 8.0 7.6 8.0 7.5 7.8 9.9 10.6 16.0 45.7 25.1 13.8 3.3 5.5 7.4 7.4 10.3 8.5 6.7 18.7 11.5 10.6 11.0 10.4 7.5 13.4 11.3 5.9 8.8 11.2 8.9 9.9 10.8 9.6 7.2 40.2 6.7 6.8 11.8 14.8 10.4 15.8 9.6 11.4 16.9 12.6 13.5 37.4 10.1 6.1 24.9 6.4 2.9 9.0 17.8 3.6 38.4 12.3 5.9 12.3 33.2 44.4 9.9 8.9 18.4 11.0 8.6 9.3 9.3 16.4 9.0 0.0 6.9 7.8 20.6 8.6 9.2 3.8 12.3 12.1 11.2 9.0 8.7 FCAR CD89 ENSG00000186431 "Fc fragment of IgA receptor" P24071 19 54874235-54891420 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "IgA-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 26.1;lung: 10.5;lymphoid tissue: 13.5" "Group enriched" "Detected in some" 6 "Kupffer cells: 12.8;Macrophages: 18.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "classical monocyte: 1.2;neutrophil: 4.0" "Group enriched" "Detected in many" 27 "granulocytes: 4.0;monocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA014050 Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA014050: AB_1846338" "unprognostic (1.46e-1)" "unprognostic (5.74e-2)" "unprognostic (1.30e-1)" "unprognostic (4.71e-3)" "unprognostic (3.46e-1)" "unprognostic (2.02e-1)" "unprognostic (7.99e-2)" "unprognostic (1.54e-2)" "unprognostic (1.59e-2)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (7.05e-2)" "unprognostic (4.19e-6)" "unprognostic (9.23e-2)" "unprognostic (8.10e-3)" "unprognostic (8.04e-3)" "unprognostic (9.81e-2)" 4.5 0.3 0.0 1.0 0.0 26.1 0.7 0.0 0.3 0.2 0.0 0.6 0.0 0.2 0.0 0.3 3.4 0.0 1.5 0.0 0.0 0.5 1.7 10.5 0.0 0.1 0.0 0.3 0.2 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.4 0.1 0.4 0.1 0.0 13.5 0.8 0.1 0.0 0.0 0.5 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.3 0.1 0.3 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 12.8 0.3 0.0 0.0 18.0 0.0 1.0 2.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.7 0.5 0.0 0.3 0.3 0.1 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.1 FCGR1A "CD64, CD64A" ENSG00000150337 "Fc fragment of IgG receptor Ia" P12314 1 149782671-149791675 "CD markers, FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 93.3;lymphoid tissue: 41.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 283.3;Kupffer cells: 140.9;Late spermatids: 64.9;Macrophages: 94.9" "Cancer enriched" "Detected in many" 4 "glioma: 10.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 131.5;intermediate monocyte: 54.7;myeloid DC: 35.6;neutrophil: 93.4" "Group enriched" "Detected in many" 53 "dendritic cells: 35.6;granulocytes: 93.4;monocytes: 131.5" "Cell line enriched" "Detected in some" 5 "THP-1: 191.6" "Low region specificity" "Detected in all" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (5.27e-2)" "unprognostic (2.89e-2)" "unprognostic (2.34e-2)" "unprognostic (7.97e-2)" "unprognostic (8.44e-3)" "unprognostic (1.73e-1)" "unprognostic (7.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (4.83e-8)" "unprognostic (1.28e-1)" "unprognostic (4.51e-2)" "unprognostic (9.99e-2)" "unprognostic (9.03e-2)" 12.2 7.2 8.4 41.3 8.9 17.9 3.6 8.8 12.8 4.2 8.4 2.3 1.1 1.6 93.3 1.7 1.8 8.2 2.2 8.6 9.4 2.8 4.2 28.6 14.4 14.6 10.6 2.3 4.3 2.7 2.5 32.6 13.0 1.6 2.1 2.3 1.9 2.4 0.3 0.4 1.3 19.1 13.2 12.5 2.1 3.7 12.2 1.4 1.4 0.8 0.8 14.7 0.8 18.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 13.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.3 191.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 24.4 0.0 2.0 131.5 1.6 0.0 54.7 0.7 1.6 0.0 0.3 35.6 0.0 0.0 0.1 93.4 0.0 11.8 0.9 0.3 48.5 8.4 8.9 8.8 12.8 8.6 9.4 14.6 10.6 13.0 13.2 12.2 18.9 0.3 0.0 3.1 0.0 0.8 0.1 0.0 0.0 0.6 1.5 0.2 0.8 1.7 1.5 1.3 0.0 2.1 2.7 0.0 0.0 0.0 0.0 30.8 0.1 0.1 9.3 0.0 2.7 0.1 0.0 1.3 1.0 0.0 0.1 0.0 0.2 1.8 0.5 283.3 0.0 0.1 0.0 0.0 140.9 6.0 64.9 0.3 94.9 0.0 7.5 34.7 0.3 0.0 0.5 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.7 1.3 6.6 0.2 0.3 0.6 0.4 0.1 0.0 4.1 0.6 0.1 0.1 0.0 FCGR1B CD64b ENSG00000198019 "Fc fragment of IgG receptor Ib" Q92637 1 121087345-121097161 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 51.5;lymphoid tissue: 18.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 86.5;Kupffer cells: 51.5;Late spermatids: 14.6;Macrophages: 36.6;monocytes: 16.4;Sertoli cells: 19.7" "Cancer enriched" "Detected in single" 4 "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 31.2;neutrophil: 36.3" "Group enriched" "Detected in many" 4 "granulocytes: 36.3;monocytes: 31.2" "Group enriched" "Detected in some" 6 "NB-4: 19.8;THP-1: 73.9" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (3.21e-2)" "unprognostic (4.35e-2)" "unprognostic (1.13e-2)" "unprognostic (2.84e-1)" "unprognostic (1.85e-1)" "unprognostic (9.60e-2)" "unprognostic (1.56e-2)" "unprognostic (6.42e-2)" "unprognostic (3.10e-2)" "unprognostic (8.17e-2)" "unprognostic (1.91e-1)" "unprognostic (3.65e-1)" "unprognostic (3.24e-10)" "unprognostic (8.99e-2)" "unprognostic (2.85e-2)" "unprognostic (7.86e-3)" "unprognostic (8.93e-2)" 5.0 3.0 4.4 18.9 4.5 6.6 1.8 4.5 7.8 1.0 3.7 0.7 0.5 0.7 51.5 0.7 0.8 1.9 1.1 4.6 4.7 1.4 1.7 6.8 2.2 6.1 5.7 0.6 2.6 0.7 1.0 11.0 6.2 0.8 0.8 0.8 0.9 0.6 0.4 0.2 0.7 5.8 6.0 7.2 0.9 0.7 6.2 0.4 2.1 0.1 0.3 4.0 0.4 6.4 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 5.9 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 19.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.1 0.0 0.3 1.0 73.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 31.2 0.6 0.0 19.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 36.3 0.0 12.4 0.3 0.0 8.8 4.4 4.5 4.5 7.8 4.6 4.7 6.1 5.7 6.2 6.0 6.2 6.4 0.4 0.0 2.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.1 0.6 2.2 0.0 0.6 0.0 2.1 0.8 0.1 0.1 0.0 0.0 7.7 0.2 0.2 2.0 0.0 0.8 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.4 0.4 0.3 86.5 3.3 0.1 0.0 0.0 51.5 4.1 14.6 1.2 36.6 0.0 11.2 16.4 0.1 1.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.4 19.7 0.6 0.1 0.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.1 FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Kupffer cells: 159.1;Langerhans cells: 336.6;Macrophages: 305.0;monocytes: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cell line enhanced" "Detected in some" "HEL: 29.4;HMC-1: 56.2;K-562: 17.9;NB-4: 15.8;THP-1: 61.9;U-937: 26.7" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" 68.0 24.8 7.3 101.7 6.6 48.6 13.3 8.0 12.1 18.1 13.9 16.0 8.1 7.3 4.3 11.7 14.6 36.8 11.5 6.5 11.5 12.7 12.3 77.5 16.1 15.1 11.4 7.2 12.7 8.5 7.6 107.3 13.3 6.1 21.0 2.3 9.9 9.6 2.6 3.5 10.8 40.9 11.9 61.8 10.1 4.4 13.8 9.8 6.4 10.2 7.7 68.3 5.2 21.8 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 29.4 0.3 0.0 0.7 8.6 56.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 17.9 0.5 0.0 0.0 0.4 15.8 0.0 0.0 1.1 0.2 1.2 8.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 61.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.7 0.4 26.7 6.6 2.4 358.3 421.8 0.7 268.4 1.0 3.2 0.5 0.4 89.9 1.7 0.4 0.7 2322.4 0.4 232.7 3.8 0.9 170.3 7.3 6.6 8.0 12.1 6.5 11.5 15.1 11.4 13.3 11.9 13.8 21.8 2.3 22.4 49.1 0.0 8.6 8.7 0.9 0.3 1.2 0.4 1.1 3.8 1.8 2.8 12.1 0.0 0.0 1.0 3.4 0.1 9.8 0.2 38.2 0.1 0.8 15.6 0.0 3.0 0.1 0.6 1.6 8.9 1.1 0.1 30.4 0.1 3.9 2.1 178.2 0.0 0.1 0.0 0.0 159.1 336.6 66.5 1.5 305.0 17.8 12.2 97.3 0.5 7.2 1.0 0.6 0.5 0.0 0.0 4.6 0.3 0.0 9.6 3.7 0.2 6.6 1.5 6.0 0.4 0.6 0.8 7.7 1.6 4.8 0.2 0.1 0.4 FCHSD2 "KIAA0769, SH3MD3" ENSG00000137478 "FCH and double SH3 domains 2" O94868 11 72836745-73142318 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 219.6;Microglial cells: 387.8;Oligodendrocyte precursor cells: 471.0;Oligodendrocytes: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 164.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038545, HPA038546" Uncertain Approved "Nuclear speckles,Plasma membrane,Actin filaments,Focal adhesion sites" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments" "Nuclear speckles, Focal adhesion sites" "HPA038545: AB_2676074, HPA038546: AB_10673013" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.71e-4)" "unprognostic (1.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.62e-3)" "unprognostic (1.41e-2)" "unprognostic (2.62e-1)" "unprognostic (1.27e-2)" "unprognostic (2.56e-1)" "unprognostic (3.69e-2)" "unprognostic (6.16e-2)" "unprognostic (2.89e-3)" "unprognostic (2.02e-1)" "unprognostic (4.70e-1)" "unprognostic (2.92e-1)" "unprognostic (1.23e-1)" 22.2 19.2 43.3 33.4 47.9 28.6 16.8 31.5 38.7 14.9 34.6 14.5 8.9 16.0 6.9 11.7 13.8 22.6 25.5 37.0 44.5 13.0 17.6 23.9 45.2 36.6 36.4 32.3 10.4 9.9 8.1 31.2 35.4 11.6 14.4 19.6 9.3 13.8 8.8 9.0 17.7 17.2 32.5 42.3 13.1 22.6 41.3 28.5 14.9 14.7 46.1 21.6 11.7 45.0 14.2 12.3 26.0 31.3 9.8 23.9 21.8 26.7 50.6 14.8 12.0 9.6 21.0 76.3 31.3 31.0 15.6 20.0 15.3 14.1 21.0 27.2 7.0 64.2 14.3 33.4 25.7 30.6 7.6 14.6 15.6 15.1 17.7 33.4 35.7 26.7 13.7 49.6 19.5 16.1 36.4 54.7 5.5 15.6 13.8 56.4 39.8 164.1 24.8 21.4 13.1 16.9 9.6 16.2 31.9 12.2 12.4 23.7 47.9 45.9 18.5 32.9 7.5 46.8 29.4 71.2 8.4 51.4 13.8 18.3 8.4 18.7 2.8 5.1 1.9 22.2 2.8 3.2 8.1 26.9 3.2 4.1 19.9 2.0 3.0 32.3 3.2 3.6 43.3 47.9 31.5 38.7 37.0 44.5 36.6 36.4 35.4 32.5 41.3 45.0 47.3 9.6 14.0 114.9 76.7 8.5 5.2 3.6 9.1 13.5 5.9 4.7 16.0 8.6 6.1 3.7 25.0 12.4 39.4 1.9 1.9 4.1 6.2 6.6 8.3 30.2 4.8 19.4 79.4 6.2 9.2 9.4 7.7 5.4 2.5 33.6 46.1 11.3 19.9 10.1 219.6 7.7 4.1 30.8 29.9 10.0 10.8 32.8 5.4 387.8 20.6 10.6 5.2 471.0 198.1 5.3 5.7 16.6 70.1 3.8 1.8 3.5 3.9 17.0 6.6 13.0 26.1 9.6 13.0 7.1 5.8 12.0 14.9 6.0 3.7 4.8 FFAR1 "FFA1R, GPR40" ENSG00000126266 "Free fatty acid receptor 1" O14842 19 35351552-35353862 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 2.8;brain: 4.8;ovary: 2.5;pancreas: 4.4" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 1.8;granulocytes: 1.3;Granulosa cells: 1.4" "Cancer enriched" "Detected in single" 13 "pancreatic cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-698: 1.6" "Not detected" "Not detected" HPA048933 Supported "Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA048933: " "unprognostic (9.49e-2)" "unprognostic (2.08e-1)" "unprognostic (1.59e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" "unprognostic (4.51e-2)" "unprognostic (1.03e-2)" "unprognostic (4.46e-2)" "unprognostic (6.19e-2)" "unprognostic (9.56e-3)" 0.0 0.0 1.5 0.1 2.1 2.8 0.0 1.4 1.9 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 1.3 1.5 0.0 0.0 0.1 0.4 2.1 1.6 2.5 4.4 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.3 0.6 0.2 1.9 0.0 0.0 0.0 0.1 0.0 0.0 4.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 2.1 1.4 1.9 1.3 1.5 2.1 1.6 2.1 1.3 1.9 4.8 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1.3 1.4 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 FGD5 "FLJ00274, FLJ39957, ZFYVE23" ENSG00000154783 "FYVE, RhoGEF and PH domain containing 5" Q6ZNL6 3 14810853-14934571 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 51.3;Endothelial cells: 44.7;Hepatic stellate cells: 55.6;Microglial cells: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 94.9;TIME: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014436, HPA014536, HPA019191" Uncertain Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA014436: , HPA014536: AB_1848518, HPA019191: AB_1848519" "unprognostic (2.57e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (3.28e-2)" "unprognostic (2.02e-2)" "unprognostic (1.03e-3)" "unprognostic (1.08e-1)" "unprognostic (4.10e-2)" "unprognostic (6.34e-2)" "unprognostic (5.53e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (6.84e-3)" "unprognostic (1.71e-2)" "unprognostic (3.46e-1)" "unprognostic (1.32e-2)" "prognostic favorable (7.50e-4)" 19.8 4.4 4.8 5.6 4.3 0.3 15.0 4.1 4.9 10.4 3.4 5.3 9.2 11.3 2.3 5.7 8.5 11.9 11.5 3.0 2.9 10.1 3.1 20.6 4.2 4.5 11.5 5.3 2.2 3.5 3.2 17.7 4.8 5.3 4.6 0.2 3.7 4.4 6.8 5.4 7.0 11.4 3.2 25.0 4.6 4.3 6.7 2.0 7.5 13.4 3.6 7.7 5.6 3.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 94.9 0.1 0.0 0.0 0.0 0.0 0.4 0.2 5.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.4 0.0 81.1 0.0 6.6 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 4.3 4.1 4.9 3.0 2.9 4.5 11.5 4.8 3.2 6.7 3.0 51.3 0.0 4.6 0.0 0.9 3.1 0.2 0.0 1.2 0.1 1.3 1.9 4.4 1.5 0.6 0.0 0.0 0.3 0.4 0.1 1.9 0.2 7.3 0.4 5.3 44.7 0.0 5.3 3.4 0.2 0.1 11.3 1.1 0.3 0.0 0.0 55.6 1.3 10.5 0.0 8.6 0.2 0.0 2.2 5.9 9.9 11.5 3.3 1.8 25.3 0.0 0.0 1.0 0.5 0.3 4.8 2.5 4.5 0.0 0.3 1.0 7.0 0.0 0.2 0.0 4.9 2.4 0.2 3.6 0.1 1.8 0.5 0.7 2.3 0.5 0.2 FLCN "BHD, DENND8B, MGC17998, MGC23445" ENSG00000154803 Folliculin Q8NFG4 17 17212212-17237188 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 79.2;Erythroid cells: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015158, HPA028760" Supported Supported "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "Plasma membrane" "CAB015158: AB_2231645, HPA028760: AB_10601323" "unprognostic (1.99e-1)" "unprognostic (1.77e-1)" "unprognostic (1.53e-2)" "unprognostic (1.74e-1)" "unprognostic (3.85e-2)" "unprognostic (3.69e-1)" "unprognostic (3.73e-2)" "unprognostic (1.32e-1)" "unprognostic (3.58e-2)" "unprognostic (3.90e-1)" "prognostic favorable (4.49e-4)" "unprognostic (6.45e-3)" "unprognostic (2.55e-3)" "unprognostic (1.92e-1)" "unprognostic (9.71e-2)" "unprognostic (2.62e-2)" "unprognostic (1.65e-1)" 21.8 19.0 19.0 10.7 25.9 17.7 18.9 27.3 31.6 42.5 18.3 43.7 23.3 37.0 14.5 13.8 25.2 17.0 29.2 31.9 14.0 15.3 28.9 26.8 12.4 21.3 15.2 35.3 15.2 13.1 28.6 13.1 22.0 27.1 10.2 7.2 16.4 13.7 42.7 19.3 26.8 14.5 14.0 29.2 22.4 21.0 19.3 8.6 23.8 18.4 8.0 28.2 25.5 28.3 12.0 30.4 11.5 14.9 36.4 20.6 15.8 11.8 19.1 18.0 24.3 24.3 10.4 6.3 13.8 14.0 40.2 14.4 14.0 7.3 9.3 10.9 12.2 12.4 9.1 13.9 33.6 4.9 33.5 30.3 24.0 27.6 20.8 16.4 14.8 9.2 17.7 16.4 17.6 17.5 8.3 8.4 11.2 17.8 8.1 16.9 52.7 7.3 11.0 14.1 13.6 8.8 11.6 7.5 19.3 70.7 11.1 8.8 15.7 40.6 16.6 56.5 14.1 7.7 7.4 5.7 26.0 10.8 16.6 2.4 2.8 1.6 1.6 3.7 2.2 3.6 1.9 1.4 1.4 3.2 2.1 1.9 6.0 2.8 1.4 1.4 2.9 1.8 19.0 25.9 27.3 31.6 31.9 14.0 21.3 15.2 22.0 14.0 19.3 28.3 8.4 25.6 12.6 17.0 9.2 18.4 12.7 5.7 2.8 20.7 13.2 6.5 23.7 14.3 6.2 7.3 79.2 10.9 5.3 25.0 1.9 12.3 14.5 16.8 11.3 12.5 25.7 81.7 31.3 8.3 7.4 20.6 9.7 15.2 1.3 10.3 27.8 24.1 16.6 47.1 23.7 11.0 16.2 21.6 19.2 20.4 28.0 13.2 10.6 18.7 12.2 13.3 6.2 17.1 32.4 9.8 15.6 20.3 4.4 11.6 36.8 6.1 9.1 18.5 19.7 24.8 11.1 6.3 10.8 5.3 18.2 33.8 10.0 16.3 12.6 13.0 FLNB "ABP-278, FH1, FLN1L, LRS1, TABP, TAP" ENSG00000136068 "Filamin B" O75369 3 58008400-58172251 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Differentiation, Myogenesis" "Actin-binding, Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 344.9;Pancreatic endocrine cells: 385.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 17.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 523.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004747, HPA004886, CAB019322" Enhanced Supported "Golgi apparatus,Plasma membrane,Actin filaments,Cytosol" NA NA 20000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments, Cytosol" "CAB019322: , HPA004747: AB_1848599, HPA004886: AB_1848600" "unprognostic (1.29e-2)" "unprognostic (1.08e-2)" "unprognostic (5.97e-2)" "unprognostic (6.86e-2)" "unprognostic (1.26e-1)" "unprognostic (2.05e-1)" "unprognostic (6.52e-2)" "unprognostic (1.72e-1)" "unprognostic (9.61e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (9.23e-2)" "prognostic favorable (3.45e-6)" "unprognostic (4.38e-2)" "unprognostic (1.36e-1)" "unprognostic (6.65e-3)" "unprognostic (2.33e-1)" 74.6 63.1 42.8 22.3 51.3 7.4 90.4 50.9 52.4 45.5 57.1 122.2 52.8 75.5 120.3 57.7 75.9 19.6 47.2 40.1 41.6 96.7 71.5 49.9 24.4 54.4 52.3 68.9 83.2 59.9 38.1 48.0 52.6 124.4 74.4 10.2 64.0 51.4 16.3 91.3 92.7 36.2 48.1 55.3 70.2 30.4 50.0 74.8 91.1 17.8 23.8 114.7 58.6 58.3 134.4 225.0 22.3 32.9 14.8 25.0 385.7 49.0 39.3 106.6 108.4 227.1 223.1 21.9 18.1 172.9 172.8 215.9 42.1 311.5 103.0 121.6 20.8 18.4 192.7 110.5 107.8 16.2 63.1 40.2 132.1 148.5 448.3 125.2 365.4 94.7 30.9 6.6 67.0 29.2 49.3 38.5 34.5 146.6 192.1 21.6 5.8 18.7 143.8 224.6 24.7 23.1 247.3 132.6 27.4 160.9 110.3 44.6 523.3 27.8 84.5 334.1 175.6 4.8 1.7 17.0 102.2 29.2 29.9 10.1 0.3 5.0 0.5 0.8 2.7 4.1 1.7 0.8 1.4 1.6 5.1 3.8 0.2 7.3 1.5 17.9 2.0 1.5 42.8 51.3 50.9 52.4 40.1 41.6 54.4 52.3 52.6 48.1 50.0 58.3 133.7 51.3 30.2 3.9 11.0 50.6 42.9 73.2 29.0 3.3 86.6 43.4 10.0 57.2 62.0 47.8 39.6 28.7 36.8 344.9 0.0 93.8 15.6 103.6 24.4 92.9 49.2 10.3 34.1 67.1 207.1 28.8 88.7 133.8 24.7 34.4 151.3 52.0 14.6 1.7 34.3 82.8 38.7 11.3 12.2 22.4 16.1 11.1 5.4 22.5 11.6 9.1 2.1 25.1 40.9 385.7 161.0 27.8 3.4 115.2 157.3 6.5 76.1 10.6 0.0 4.4 25.9 4.4 6.9 46.4 51.7 49.8 9.9 84.6 93.0 88.4 FLNC "ABP-280, ABPL, FLN2" ENSG00000128591 "Filamin C" Q14315 7 128830406-128859274 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 635.2;skeletal muscle: 1384.8;tongue: 442.6" "Cell type enriched" "Detected in many" 26 "Cardiomyocytes: 1892.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 393.6;fHDF/TERT166: 180.2;hTEC/SVTERT24-B: 190.6;U-2 OS: 163.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA006135, HPA071007" Enhanced Supported "Plasma membrane,Cytosol" NA NA 26000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA006135: AB_1848602, HPA071007: " "unprognostic (1.25e-1)" "unprognostic (7.38e-2)" "unprognostic (4.47e-2)" "unprognostic (1.40e-2)" "prognostic unfavorable (2.80e-4)" "unprognostic (1.64e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (2.17e-5)" "unprognostic (1.03e-3)" "unprognostic (2.35e-2)" "unprognostic (1.35e-3)" "unprognostic (6.37e-2)" "prognostic unfavorable (5.69e-4)" "unprognostic (5.68e-3)" "unprognostic (1.15e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (3.73e-5)" 13.1 3.4 5.8 25.9 11.5 0.0 5.9 11.5 9.9 16.9 3.0 215.4 9.4 96.6 4.6 40.3 35.4 13.8 635.2 5.9 16.7 2.8 1.1 12.5 0.6 52.1 11.1 9.4 2.1 3.2 1.6 2.4 29.9 71.1 9.8 0.5 16.5 100.7 1384.8 8.9 40.3 114.4 51.7 0.7 65.6 2.2 19.1 0.3 4.3 442.6 0.2 162.7 21.3 49.8 0.1 0.8 4.2 0.1 34.4 41.2 4.1 393.6 73.6 109.2 52.3 124.0 1.0 0.1 64.7 180.2 44.9 0.1 23.7 0.9 64.4 0.2 13.1 0.1 20.2 0.1 43.2 0.0 0.2 78.0 0.1 190.6 0.1 44.2 69.0 0.3 49.0 0.2 75.8 0.0 0.0 1.5 64.5 0.1 22.6 0.1 127.5 1.0 0.1 0.0 2.1 7.0 0.7 0.1 0.3 88.0 0.4 1.6 144.6 38.2 163.5 10.1 0.2 0.1 0.0 0.3 129.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 11.5 11.5 9.9 5.9 16.7 52.1 11.1 29.9 51.7 19.1 49.8 3.6 3.2 0.5 0.7 0.0 3.7 0.3 0.1 1.2 0.6 0.3 1.3 1892.3 0.0 1.9 1.8 0.0 0.4 0.2 0.5 0.0 0.7 0.4 1.8 5.0 31.4 0.0 0.0 0.2 0.2 3.0 31.6 0.0 2.9 0.0 0.6 1.8 0.0 0.9 0.0 1.1 0.3 0.0 0.0 6.9 0.9 5.3 0.5 5.4 0.0 0.0 0.1 0.0 0.0 5.8 2.6 0.1 10.5 1.2 2.7 0.0 1.1 0.0 0.2 0.0 71.8 38.1 0.3 1.0 0.2 4.5 1.9 1.0 0.1 0.2 1.0 FLOT1 ENSG00000137312 "Flotillin 1" O75955 6 30727709-30742732 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 314.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 423.3;hTERT-RPE1: 242.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001393, CAB007766" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA 160000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "Vesicles, Plasma membrane" "CAB007766: AB_562116, HPA001393: AB_1078892" "unprognostic (2.68e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (5.78e-4)" "unprognostic (1.78e-2)" "unprognostic (2.21e-1)" "unprognostic (3.41e-3)" "unprognostic (2.68e-3)" "unprognostic (1.86e-1)" "unprognostic (2.65e-1)" "prognostic favorable (3.06e-4)" "unprognostic (1.81e-2)" "unprognostic (9.36e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (6.43e-3)" "unprognostic (3.92e-1)" "unprognostic (1.61e-2)" "unprognostic (2.46e-2)" 141.7 239.5 49.3 27.9 54.6 41.7 129.8 49.4 60.9 111.1 56.8 150.3 28.7 108.9 8.4 81.8 95.8 23.1 234.5 55.1 57.9 146.1 127.3 136.8 22.1 50.9 51.5 84.1 88.5 41.4 102.5 35.0 57.4 109.6 17.7 6.3 99.1 45.8 190.0 51.7 87.1 33.0 45.8 129.6 96.9 65.0 53.6 24.9 111.7 83.1 17.0 134.5 96.9 48.8 54.3 18.3 46.4 62.0 49.1 71.0 1.3 59.7 67.5 82.8 79.3 19.4 30.0 13.0 29.0 101.3 423.3 41.8 35.0 20.1 28.6 36.1 1.3 41.1 17.5 19.1 119.2 12.2 67.0 75.4 30.6 40.9 71.3 242.7 65.9 37.9 21.7 52.7 77.9 22.9 38.0 14.5 15.1 29.4 15.7 20.2 48.4 38.0 30.3 13.0 16.4 17.2 33.7 28.7 164.6 30.4 43.8 10.1 44.0 199.5 37.6 20.6 120.6 18.6 19.7 28.8 26.2 42.6 122.7 179.3 76.9 132.0 35.0 38.9 24.1 28.0 21.3 30.4 58.9 23.0 23.7 27.4 314.3 79.9 26.3 59.2 3.9 58.3 49.3 54.6 49.4 60.9 55.1 57.9 50.9 51.5 57.4 45.8 53.6 48.8 175.4 89.8 77.0 26.1 38.1 28.7 111.5 44.9 80.2 14.7 72.1 73.4 90.6 62.9 59.2 84.6 6.2 82.2 57.7 103.2 123.3 77.6 60.2 73.9 50.1 141.6 68.8 41.7 41.3 85.9 70.7 67.6 55.5 75.2 143.3 41.4 154.9 59.7 130.6 20.2 40.2 66.6 57.0 61.3 84.9 144.1 61.8 89.4 71.2 28.1 99.2 64.7 68.0 27.2 22.7 65.7 112.0 38.0 60.4 69.5 89.0 172.1 80.7 18.1 52.6 58.1 65.9 80.2 26.7 63.7 26.9 61.6 51.2 29.1 83.2 99.4 FLOT2 "ECS-1, ECS1, ESA, ESA1, M17S1" ENSG00000132589 "Flotillin 2" Q14254 17 28879335-28897733 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001396, CAB004395, HPA071038" Supported Supported "Vesicles,Plasma membrane" NA NA 170000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" Vesicles "CAB004395: AB_627618, HPA001396: AB_1078894, HPA071038: " "unprognostic (6.04e-2)" "unprognostic (8.76e-3)" "unprognostic (3.01e-1)" "unprognostic (8.92e-2)" "unprognostic (4.15e-3)" "unprognostic (2.17e-2)" "unprognostic (4.36e-3)" "unprognostic (2.12e-1)" "unprognostic (5.21e-2)" "unprognostic (1.20e-1)" "unprognostic (9.98e-2)" "unprognostic (2.80e-1)" "unprognostic (4.12e-3)" "unprognostic (2.64e-2)" "unprognostic (1.09e-1)" "unprognostic (1.11e-3)" "unprognostic (2.20e-2)" 60.2 46.4 38.4 56.8 38.6 97.1 56.2 28.1 47.6 42.8 45.2 58.9 21.0 39.1 21.2 69.3 46.8 27.0 63.5 41.1 42.5 71.4 98.4 59.5 68.2 45.9 37.1 37.7 38.8 30.0 22.3 58.4 41.3 67.8 27.2 20.3 61.7 51.6 51.6 38.2 53.0 35.3 37.5 122.7 44.6 10.4 47.1 47.8 39.6 44.1 63.6 78.8 49.6 36.1 55.5 90.8 69.6 60.2 33.6 44.2 76.6 42.5 57.9 60.9 71.3 96.0 45.7 76.9 79.3 47.6 42.0 63.3 76.5 69.7 25.9 245.5 91.4 92.7 80.5 70.3 43.6 76.8 15.2 53.3 53.6 49.3 66.9 64.1 97.4 21.8 89.0 65.6 28.9 83.5 21.2 54.0 61.4 48.6 24.6 32.6 70.6 189.3 92.0 166.9 61.9 103.3 99.8 69.6 77.5 66.7 72.3 136.3 81.5 21.4 38.2 35.2 65.0 36.5 68.2 39.5 59.9 72.3 40.7 171.9 106.0 213.2 98.8 96.6 72.6 98.5 74.6 84.5 144.3 118.1 55.3 69.0 415.2 78.5 110.2 38.8 97.6 143.2 38.4 38.6 28.1 47.6 41.1 42.5 45.9 37.1 41.3 37.5 47.1 36.1 34.2 22.4 21.9 12.7 46.8 12.6 27.1 20.6 29.6 6.9 24.9 30.1 32.9 22.8 16.5 20.2 10.4 96.6 20.5 29.0 15.6 39.3 13.0 25.8 13.2 37.0 25.8 49.2 17.0 31.1 68.9 14.8 23.0 27.6 6.3 15.6 48.9 45.1 44.4 5.0 19.2 25.9 10.2 43.3 22.6 42.3 10.8 31.1 8.8 22.5 75.2 10.7 35.0 16.1 11.0 32.2 16.5 8.6 27.8 14.8 14.8 26.7 19.1 12.4 19.7 7.1 13.4 1.6 6.9 42.4 9.2 37.1 32.5 4.2 32.0 26.7 FLRT3 ENSG00000125848 "Fibronectin leucine rich transmembrane protein 3" Q9NZU0 20 14322985-14337614 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 218.0;Alveolar cells type 2: 156.5;Basal prostatic cells: 168.3;Club cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 27.5;hTCEpi: 51.3;RPTEC TERT1: 17.3;WM-115: 62.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056033 Enhanced Supported "Plasma membrane,Cell Junctions,Cytosol" "Intracellular and membrane" NA NA 1100000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions, Cytosol" "HPA056033: AB_2683016" "unprognostic (2.14e-1)" "unprognostic (2.57e-1)" "unprognostic (2.98e-1)" "unprognostic (1.14e-3)" "unprognostic (2.30e-1)" "unprognostic (6.00e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.85e-5)" "unprognostic (1.24e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (3.05e-1)" "prognostic favorable (1.49e-7)" "unprognostic (1.54e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-3)" "unprognostic (3.65e-1)" 5.0 3.7 2.3 0.8 3.0 0.0 2.3 6.4 5.3 3.2 0.9 1.6 11.8 2.3 3.1 1.6 2.4 5.0 0.6 5.3 1.3 23.2 7.0 17.7 0.1 0.0 1.3 10.6 1.2 8.2 1.0 1.8 0.8 8.2 0.8 1.6 1.2 14.0 2.0 6.3 2.3 1.4 0.6 0.7 9.7 1.2 2.3 7.3 5.2 0.7 0.3 7.9 2.1 1.8 0.0 12.2 27.5 0.0 0.0 0.0 0.0 2.7 0.8 0.1 0.0 15.3 5.6 0.0 0.9 0.6 0.0 8.0 0.0 8.3 0.1 0.0 1.8 0.0 0.4 0.3 2.4 0.0 0.0 4.6 51.3 0.0 9.7 0.0 0.1 0.2 0.0 0.2 5.3 0.4 3.7 0.0 8.9 6.2 0.1 0.1 0.2 0.0 17.3 3.6 0.5 5.7 0.0 0.0 9.2 15.5 0.5 0.0 0.0 0.0 1.8 0.1 0.7 0.0 0.0 0.0 0.2 0.0 62.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 6.4 5.3 5.3 1.3 0.0 1.3 0.8 0.6 2.3 1.8 0.3 218.0 156.5 2.3 0.5 8.7 168.3 26.1 55.8 23.9 4.4 6.5 1.2 24.3 73.1 22.0 6.2 0.5 0.0 2.2 13.7 23.6 0.2 0.7 1.7 1.9 11.3 0.0 27.2 14.9 0.0 8.7 37.8 0.7 5.1 5.0 2.9 8.5 0.2 6.7 39.3 2.5 2.0 0.3 0.7 0.5 3.7 1.3 5.4 1.9 1.6 0.6 0.0 26.2 3.9 10.0 3.0 0.4 0.1 24.9 3.5 49.2 13.4 3.3 0.0 25.0 1.8 0.0 0.1 5.9 16.6 0.0 0.8 1.4 1.5 18.3 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 432.4" "Cell type enhanced" "Detected in many" "Adipocytes: 411.6;Endothelial cells: 263.1;Extravillous trophoblasts: 815.4;Hepatic stellate cells: 234.9;Microglial cells: 433.8;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 71.8;BJ hTERT+: 57.2;HMC-1: 349.2;HUVEC TERT2: 64.9;WM-115: 127.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 87000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 47.6 9.6 37.6 9.1 36.2 1.1 31.2 37.0 43.0 16.4 24.6 9.4 7.5 17.2 3.7 5.9 11.7 16.6 46.0 33.3 39.8 34.9 18.2 25.8 5.3 44.6 40.0 4.4 12.7 30.5 9.0 432.4 50.1 13.9 6.1 52.5 7.0 11.0 19.9 5.9 9.3 17.4 33.4 18.6 10.9 17.4 59.6 3.6 48.9 38.8 5.7 14.0 9.5 38.7 0.1 0.0 0.0 0.6 0.6 0.9 0.3 71.8 57.2 25.8 14.9 0.0 0.2 0.1 0.1 9.6 0.0 0.3 6.7 0.0 45.4 0.0 2.0 0.2 0.1 0.0 0.1 0.0 349.2 0.6 0.0 0.1 1.0 0.1 64.9 6.1 1.7 0.3 0.0 0.3 4.5 3.7 37.5 0.0 0.1 2.9 0.0 0.1 0.1 0.1 8.1 0.6 0.0 0.1 0.2 44.4 0.3 0.2 6.3 0.2 1.2 0.1 0.1 2.1 1.0 0.2 0.4 0.3 127.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 37.6 36.2 37.0 43.0 33.3 39.8 44.6 40.0 50.1 33.4 59.6 38.7 411.6 0.0 6.0 2.0 4.7 4.1 0.7 0.2 3.4 17.8 1.2 1.5 26.5 2.8 2.9 0.0 4.2 197.2 1.4 0.1 1.9 0.6 157.2 0.5 1.5 263.1 0.0 0.0 0.9 0.0 815.4 32.1 0.5 2.1 1.3 0.1 234.9 6.9 30.8 1.7 14.5 0.0 0.0 12.5 23.6 173.8 18.6 15.3 0.0 433.8 0.0 153.2 0.0 9.5 2.0 0.0 0.0 48.5 4.1 1.3 0.0 0.1 1.8 9.7 92.1 11.4 30.1 14.6 4.6 1.0 4.8 1127.1 2.8 1.5 0.0 1.1 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 FMNL3 "DKFZp762B245, MGC45819, WBP3" ENSG00000161791 "Formin like 3" Q8IVF7 12 49636499-49708165 "Predicted intracellular proteins" Angiogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 35.8;Cone photoreceptor cells: 39.6;dendritic cells: 48.6;Microglial cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 47.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002552, HPA023201" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles, Plasma membrane" Cytosol "HPA002552: AB_1078862, HPA023201: AB_1848575" "unprognostic (2.97e-1)" "unprognostic (2.77e-3)" "unprognostic (4.97e-3)" "unprognostic (7.19e-2)" "unprognostic (5.42e-2)" "unprognostic (2.33e-3)" "unprognostic (5.37e-3)" "unprognostic (1.52e-2)" "unprognostic (2.83e-1)" "unprognostic (1.54e-1)" "unprognostic (6.67e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (3.58e-5)" "unprognostic (1.04e-1)" "unprognostic (2.31e-1)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" 12.2 5.7 13.7 20.5 13.2 5.2 10.6 13.0 11.2 9.6 3.0 8.0 5.7 11.2 19.2 4.5 6.9 11.1 12.6 11.0 12.6 9.3 2.7 17.4 23.5 21.7 14.6 16.1 3.2 3.6 4.1 14.0 18.2 6.0 5.6 2.7 4.6 4.4 5.6 4.4 10.2 11.5 17.7 13.4 6.6 10.1 20.4 20.1 13.4 6.7 28.3 8.6 6.3 20.4 8.6 2.5 18.4 6.1 5.0 20.1 0.2 10.4 21.0 13.8 12.1 9.7 2.3 18.2 19.5 12.4 15.2 0.4 9.5 4.3 12.6 16.2 3.6 20.1 2.9 0.5 8.8 4.0 25.1 12.7 0.7 21.7 9.1 41.2 37.1 9.0 4.6 13.0 20.5 6.3 16.6 6.0 6.0 0.9 5.5 7.9 23.0 2.8 13.1 1.3 3.0 8.6 6.0 0.8 11.8 9.3 1.5 5.9 47.2 34.2 11.8 0.6 18.2 6.7 0.4 9.8 21.3 12.4 14.7 3.0 0.1 0.8 0.8 0.4 0.4 0.2 0.3 0.5 0.2 1.1 0.4 0.5 0.0 0.6 0.3 5.1 0.1 0.5 13.7 13.2 13.0 11.2 11.0 12.6 21.7 14.6 18.2 17.7 20.4 20.4 35.8 3.2 3.4 6.8 17.5 1.7 0.7 0.4 2.2 11.3 1.3 2.3 3.3 0.0 1.4 1.8 39.6 2.1 48.6 0.1 0.0 0.3 2.0 0.7 2.6 29.7 0.0 1.7 16.0 0.6 0.8 7.1 1.5 2.0 27.8 5.4 15.7 0.8 11.1 3.3 6.5 0.8 0.0 6.9 9.0 4.6 3.7 17.7 5.4 119.0 22.9 0.5 16.5 27.6 5.5 0.8 0.1 6.4 1.8 0.8 0.0 0.2 0.2 2.0 13.1 15.5 10.3 5.9 7.5 0.4 1.4 2.5 13.6 2.6 0.1 0.4 FNBP1 "FBP17, KIAA0554" ENSG00000187239 "Formin binding protein 1" Q96RU3 9 129887187-130043194 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 317.7;Langerhans cells: 402.9;monocytes: 433.2;Oligodendrocytes: 522.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 137.7;JURKAT: 143.2;MOLT-4: 140.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019635, HPA019691, HPA022119, HPA067742" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane" Vesicles "HPA019635: AB_2732423, HPA019691: AB_2670231, HPA022119: AB_2670897, HPA067742: " "unprognostic (2.86e-1)" "unprognostic (2.59e-3)" "unprognostic (1.22e-2)" "unprognostic (2.10e-1)" "unprognostic (3.20e-1)" "unprognostic (1.43e-2)" "unprognostic (6.30e-3)" "unprognostic (9.10e-2)" "unprognostic (2.90e-1)" "unprognostic (6.17e-2)" "unprognostic (9.26e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (8.45e-5)" "unprognostic (6.84e-2)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-1)" 21.8 11.9 51.2 57.8 73.7 40.6 16.4 77.4 53.4 32.5 22.2 107.3 15.0 50.0 17.0 39.4 34.8 27.8 15.1 47.0 62.5 16.4 18.4 25.4 78.1 67.6 69.1 22.1 8.1 10.7 17.7 16.3 65.8 41.4 29.6 12.6 16.3 44.1 24.1 25.9 37.6 46.8 55.9 60.9 29.6 17.3 69.9 111.0 33.4 13.2 74.3 68.4 26.8 86.6 42.5 19.3 34.9 40.8 21.0 25.8 29.5 23.7 20.2 17.6 14.7 20.3 16.2 82.9 20.4 44.5 20.8 20.7 33.0 21.6 17.6 137.7 9.8 22.8 22.8 13.8 35.8 62.3 75.1 18.7 9.3 32.6 19.5 25.6 26.1 143.2 5.4 1.1 16.4 34.0 140.1 60.8 27.5 5.7 32.6 31.9 28.3 24.1 22.1 23.0 5.5 17.6 43.3 42.9 16.5 33.3 30.0 28.3 31.9 16.6 20.7 30.5 15.0 16.4 64.4 3.8 20.0 42.2 25.2 13.2 5.1 9.6 10.8 5.6 9.3 12.7 9.7 10.3 5.8 7.7 8.9 8.6 9.3 6.0 6.5 6.9 10.9 4.5 51.2 73.7 77.4 53.4 47.0 62.5 67.6 69.1 65.8 55.9 69.9 86.6 27.2 35.3 25.2 317.7 180.4 33.1 21.3 12.8 21.6 20.2 42.5 24.6 14.8 15.7 29.8 22.0 52.1 18.6 217.2 28.3 19.6 22.6 1.7 46.2 38.8 38.3 18.1 31.3 65.6 17.3 24.5 38.8 26.5 78.7 80.4 9.2 71.0 18.4 43.6 28.6 107.8 8.7 20.3 221.2 402.9 5.5 46.6 131.1 76.5 95.5 433.2 42.8 223.5 69.4 522.1 21.8 19.8 51.6 147.9 67.8 0.2 15.0 42.3 29.5 59.2 19.9 41.0 26.5 45.4 26.7 41.1 63.9 233.7 7.1 16.2 42.3 FRMD8 "FKSG44, FLJ90369, iTAP" ENSG00000126391 "FERM domain containing 8" Q9BZ67 11 65386621-65413525 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 129.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002861 Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 17: WM-115 - Nervous system development" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Centriolar satellite" "Nucleoplasm, Cytosol" "HPA002861: AB_1078878" "unprognostic (1.54e-1)" "unprognostic (4.07e-1)" "unprognostic (6.28e-2)" "unprognostic (1.73e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (9.94e-5)" "unprognostic (9.12e-3)" "unprognostic (1.51e-2)" "unprognostic (6.36e-3)" "unprognostic (1.90e-2)" "unprognostic (6.41e-3)" "unprognostic (4.19e-3)" "unprognostic (1.47e-2)" "unprognostic (7.36e-3)" "unprognostic (3.34e-1)" "unprognostic (2.91e-2)" 19.8 17.5 9.6 11.8 11.0 13.0 19.7 12.2 14.5 20.8 9.1 15.0 11.7 14.6 5.3 37.3 15.8 11.6 17.1 13.1 7.9 19.7 13.4 23.5 15.6 12.9 11.3 12.2 23.0 4.0 11.6 10.4 11.4 15.8 6.7 1.7 18.0 6.5 14.8 34.0 23.8 6.6 9.5 40.8 13.4 18.0 11.5 11.1 17.8 5.1 13.6 14.6 26.4 16.2 17.8 22.1 8.7 20.4 23.0 12.0 15.6 20.1 18.1 16.7 12.7 21.2 28.5 21.9 41.9 27.6 11.6 30.3 11.3 16.9 7.0 38.8 10.6 29.9 21.5 11.7 12.4 16.9 44.8 14.9 13.2 15.7 8.2 8.9 26.6 23.2 25.5 23.5 18.3 23.9 26.6 24.6 10.2 13.0 28.7 33.7 16.6 25.2 13.5 21.8 18.9 14.0 15.0 60.1 47.7 7.7 22.0 13.7 23.6 18.4 19.7 26.1 12.3 41.0 22.5 20.4 16.0 10.7 129.8 1.1 12.4 17.7 13.1 13.2 14.1 12.5 9.6 16.7 11.3 9.6 8.8 9.8 23.0 8.2 19.6 13.4 10.8 12.3 9.6 11.0 12.2 14.5 13.1 7.9 12.9 11.3 11.4 9.5 11.5 16.2 30.3 3.2 5.8 2.0 20.5 54.3 22.5 17.7 6.2 5.4 15.4 12.6 7.4 12.8 13.8 12.9 0.0 6.4 25.8 29.3 7.9 21.0 22.3 20.1 12.1 24.8 13.1 24.0 13.4 29.1 15.5 13.0 10.7 23.1 14.0 27.3 37.5 11.0 16.0 5.0 4.9 20.5 8.2 20.2 68.7 4.6 6.2 18.7 19.6 10.3 21.6 4.3 18.6 5.0 10.3 33.8 14.0 7.2 11.9 28.1 32.8 4.6 14.3 4.5 6.6 11.4 14.4 5.3 9.6 24.9 83.5 11.4 21.9 35.2 14.6 35.7 FSCN1 "FLJ38511, p55, SNL" ENSG00000075618 "Fascin actin-bundling protein 1" Q16658 7 5592816-5606655 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 256.5;Hofbauer cells: 274.2;monocytes: 1028.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 600.3;Hep G2: 464.9;K-562: 533.6;NB-4: 600.9;PC-3: 508.2;SH-SY5Y: 482.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000121, HPA005723, CAB035991, HPA050654" Enhanced Supported "Plasma membrane,Cytosol" NA Yes 4300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Plasma membrane" "CAB000121: AB_2278596, CAB035991: , HPA005723: AB_1849159, HPA050654: AB_2681203" "unprognostic (1.91e-1)" "unprognostic (2.03e-2)" "unprognostic (3.12e-2)" "unprognostic (5.00e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (2.16e-3)" "prognostic unfavorable (2.28e-4)" "unprognostic (6.31e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.15e-7)" "unprognostic (1.21e-2)" "unprognostic (8.57e-2)" "unprognostic (1.05e-2)" "unprognostic (6.93e-3)" 27.5 39.7 41.5 31.1 62.2 8.3 24.9 26.3 57.2 33.7 10.7 12.1 4.4 19.7 0.7 69.4 15.6 7.6 15.8 39.4 28.2 17.3 8.3 27.6 14.5 49.4 42.7 47.7 5.5 2.3 20.2 27.9 22.8 10.3 1.7 3.4 23.8 2.4 7.3 56.3 12.6 5.7 20.9 55.6 9.3 42.5 79.0 9.0 25.6 2.1 8.3 20.4 41.6 77.1 62.3 139.3 91.2 326.3 34.8 65.4 600.3 144.2 62.4 24.2 26.1 98.5 15.6 1.3 172.0 63.5 24.3 231.3 52.2 229.9 2.1 70.6 28.7 4.8 142.0 464.9 18.0 0.2 13.9 40.8 66.6 46.1 37.2 40.4 118.3 0.7 533.6 0.9 31.6 6.9 2.0 600.9 238.4 4.2 508.2 140.0 22.3 2.3 34.9 5.9 73.1 482.4 121.0 2.6 5.3 58.5 3.9 38.4 246.4 167.4 289.3 99.1 151.0 0.9 0.8 0.7 107.8 0.6 317.2 0.0 0.8 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 41.5 62.2 26.3 57.2 39.4 28.2 49.4 42.7 22.8 20.9 79.0 77.1 90.0 3.2 4.1 1.6 8.3 181.2 26.7 75.1 189.5 9.4 32.3 44.3 10.4 1.5 13.4 1.8 0.0 6.7 10.8 3.9 0.0 12.8 14.3 8.0 37.8 120.6 42.1 28.0 12.1 5.1 110.8 48.9 10.7 10.1 16.5 256.5 84.6 0.8 274.2 0.0 10.9 5.4 8.2 28.0 136.1 12.3 25.4 27.4 51.6 23.4 1028.2 73.5 0.0 4.5 43.2 15.5 1.1 9.1 4.2 7.5 0.4 0.4 2.9 2.6 0.0 29.7 46.3 5.7 8.0 121.2 147.2 14.6 12.2 8.3 2.6 28.0 FZD1 DKFZp564G072 ENSG00000157240 "Frizzled class receptor 1" Q9UP38 7 91264433-91271326 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 44.9;Cholangiocytes: 45.8;Horizontal cells: 141.3;Peritubular cells: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.0;non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 5 "monocytes: 2.8" "Cell line enhanced" "Detected in many" "AF22: 24.8;HSkMC: 32.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013008 Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "CAB013008: " "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (4.51e-3)" "unprognostic (2.09e-1)" "unprognostic (5.29e-3)" "unprognostic (3.70e-2)" "unprognostic (2.36e-2)" "unprognostic (5.48e-3)" "unprognostic (2.14e-1)" "unprognostic (7.39e-3)" "prognostic favorable (8.87e-7)" "unprognostic (1.05e-2)" "unprognostic (4.16e-2)" "unprognostic (5.53e-2)" "unprognostic (4.13e-2)" 5.4 4.4 2.4 2.7 2.5 1.1 10.7 5.8 2.4 9.9 11.1 5.9 5.1 8.6 4.3 5.2 5.5 5.7 12.7 4.7 2.9 9.6 2.5 10.7 1.3 2.5 6.2 10.1 4.7 2.4 3.9 10.0 2.3 10.3 3.7 2.0 9.0 16.4 1.9 10.4 5.1 5.3 2.3 3.2 4.6 1.6 3.4 1.8 20.5 2.4 1.3 6.4 11.2 2.0 0.8 2.5 24.8 2.6 19.8 17.0 4.5 9.2 5.8 3.3 2.3 1.1 4.3 0.0 2.2 5.9 4.2 4.7 3.9 2.0 2.2 0.0 4.9 0.2 4.6 1.3 1.4 4.2 1.0 32.3 3.6 7.6 2.4 12.6 0.7 2.8 1.5 3.6 9.7 6.2 0.8 1.1 6.4 1.3 4.2 5.1 15.3 0.4 5.3 11.8 3.4 6.5 7.0 5.6 1.6 5.7 3.0 3.8 3.8 13.9 10.4 15.0 3.8 3.3 2.5 0.4 15.0 3.5 16.5 0.0 0.6 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.2 2.4 2.5 5.8 2.4 4.7 2.9 2.5 6.2 2.3 2.3 3.4 2.0 5.7 3.2 1.5 4.6 1.1 4.2 44.9 7.0 10.8 1.6 27.7 29.5 18.5 45.8 4.6 12.9 2.1 3.4 0.6 7.4 0.0 4.3 0.3 12.0 13.1 4.5 3.5 0.8 0.6 2.0 2.2 18.5 2.0 15.7 12.7 1.8 15.4 0.9 3.5 141.3 1.0 3.0 4.1 17.4 16.2 1.1 33.2 14.3 17.8 1.9 4.6 3.0 1.0 1.0 0.2 1.9 4.8 45.1 0.4 11.7 6.0 11.6 2.4 2.9 0.0 6.2 10.3 0.5 3.7 9.1 5.1 2.1 0.6 2.6 4.6 7.3 FZD6 Hfz6 ENSG00000164930 "Frizzled class receptor 6" O60353 8 103298433-103332866 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 73.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 4 "NK-cells: 4.0" "Cell line enhanced" "Detected in many" "hTCEpi: 127.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017991 Approved Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA017991: AB_1849138" "unprognostic (8.22e-3)" "unprognostic (2.64e-1)" "unprognostic (4.75e-2)" "unprognostic (2.57e-1)" "unprognostic (1.22e-2)" "unprognostic (6.99e-2)" "unprognostic (4.01e-2)" "unprognostic (2.74e-1)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.20e-6)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (2.86e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (7.54e-2)" 11.7 10.6 3.0 4.2 2.8 1.0 15.1 3.1 4.3 14.2 5.7 7.0 5.7 13.0 9.5 18.7 23.5 10.6 9.1 2.9 3.0 14.5 4.0 18.6 5.1 3.8 3.1 5.4 11.2 25.3 9.8 15.1 3.8 12.6 7.0 4.6 11.7 10.3 2.0 24.0 4.6 9.3 3.0 4.0 7.4 3.6 3.3 10.0 22.3 5.6 9.9 21.6 10.2 3.2 59.8 11.0 29.6 0.0 7.9 20.6 17.1 31.0 34.1 27.2 17.6 6.2 47.8 0.0 51.4 29.7 9.1 90.3 16.8 65.7 51.0 13.5 18.0 31.4 12.2 8.5 93.4 0.0 0.0 23.0 127.6 29.4 91.5 67.1 58.2 7.0 3.2 27.0 31.5 25.5 29.8 2.7 6.7 4.7 20.6 2.3 12.3 0.0 59.1 39.5 10.0 7.9 44.8 22.8 59.9 15.8 0.0 11.6 4.1 6.1 32.0 24.9 32.7 6.4 3.7 13.3 18.0 0.0 40.4 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.8 0.4 0.3 0.5 0.9 0.4 0.0 4.0 0.0 0.1 0.4 0.2 3.0 2.8 3.1 4.3 2.9 3.0 3.8 3.1 3.8 3.0 3.3 3.2 38.3 25.6 22.5 10.1 2.8 46.9 15.9 51.1 42.7 4.1 16.1 12.7 4.8 8.6 35.4 12.9 2.1 22.7 2.1 4.9 0.0 11.7 9.6 51.0 5.8 42.0 5.3 6.7 19.9 8.2 7.1 7.0 14.8 73.6 0.0 11.2 13.9 3.7 2.4 6.7 7.3 7.4 26.4 1.0 5.1 2.9 1.2 1.3 14.2 16.9 0.7 11.8 1.0 8.5 3.6 9.5 3.2 1.5 8.6 13.4 2.8 7.1 53.8 4.8 0.0 1.6 7.7 7.0 0.8 41.9 44.6 14.6 3.0 1.7 5.6 23.2 GAB2 KIAA0571 ENSG00000033327 "GRB2 associated binding protein 2" Q9UQC2 11 78215293-78418348 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 97.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 147.9;Microglial cells: 204.2;Oligodendrocyte precursor cells: 142.7;Oligodendrocytes: 480.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.0;neutrophil: 20.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 20.1" "Cell line enhanced" "Detected in many" "SH-SY5Y: 62.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000271, HPA001368, CAB022159" Enhanced Supported "Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB022159: , HPA000271: AB_1078925, HPA001368: AB_2666287" "unprognostic (2.51e-2)" "unprognostic (1.90e-1)" "unprognostic (3.56e-3)" "unprognostic (1.99e-3)" "unprognostic (1.04e-2)" "unprognostic (4.69e-2)" "unprognostic (4.47e-2)" "unprognostic (1.08e-1)" "unprognostic (6.54e-2)" "unprognostic (1.37e-1)" "unprognostic (2.25e-1)" "unprognostic (1.74e-1)" "prognostic favorable (9.32e-5)" "unprognostic (6.95e-2)" "unprognostic (4.35e-1)" "unprognostic (3.99e-2)" "unprognostic (1.67e-2)" 18.5 8.2 69.5 12.9 80.7 39.9 11.6 56.2 65.3 14.8 31.2 9.4 14.4 19.8 3.1 8.9 13.6 9.3 14.5 54.5 68.4 6.7 4.4 20.0 7.0 79.4 70.9 20.0 6.8 6.8 8.8 15.5 74.0 7.0 11.0 3.5 7.1 7.1 6.4 13.3 10.7 17.3 68.0 13.1 8.2 5.7 72.0 21.3 6.6 6.8 5.8 10.6 10.9 97.9 3.7 3.1 8.8 1.0 12.7 5.4 39.1 5.7 6.8 4.0 3.3 23.8 1.9 1.1 24.8 7.9 1.0 5.9 21.2 0.5 5.2 36.3 2.2 14.6 5.9 4.2 6.3 5.6 2.8 6.1 1.9 15.6 2.4 11.8 23.4 4.2 38.8 1.2 6.7 1.5 2.8 13.8 2.8 8.4 4.4 27.4 8.5 0.5 7.3 13.4 7.6 62.1 1.4 2.9 14.4 12.7 13.2 15.5 19.4 1.8 4.5 15.2 1.4 9.8 1.5 0.6 1.5 8.6 16.8 13.0 3.1 0.9 0.0 1.7 0.0 0.7 0.0 0.0 1.0 0.4 0.0 0.0 20.1 0.0 4.9 2.2 0.2 1.0 69.5 80.7 56.2 65.3 54.5 68.4 79.4 70.9 74.0 68.0 72.0 97.9 6.6 3.2 20.7 57.5 8.7 2.0 0.7 0.5 0.6 4.3 3.6 2.7 10.9 1.5 1.1 0.0 0.0 5.0 4.0 9.2 0.0 2.5 7.0 5.5 9.1 7.6 10.7 4.2 80.7 6.4 16.6 6.9 6.6 10.6 5.7 50.4 5.3 0.8 12.1 16.8 147.9 4.0 4.1 29.5 17.5 5.1 8.1 22.8 7.2 204.2 17.5 0.5 1.0 142.7 480.3 8.2 3.3 10.9 4.2 4.3 10.5 0.8 2.6 2.1 13.1 8.3 5.4 3.7 1.7 1.8 2.8 22.2 3.5 3.5 8.9 2.2 GABRG1 ENSG00000163285 "Gamma-aminobutyric acid type A receptor subunit gamma1" Q8N1C3 4 46035769-46124054 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 44.7" "Cell type enriched" "Detected in some" 8 "Astrocytes: 135.5" "Cancer enriched" "Detected in single" 8 "glioma: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035622, HPA058102" Approved Supported "Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA035622: AB_10603669, HPA058102: " "unprognostic (2.50e-1)" "unprognostic (2.20e-1)" "unprognostic (6.06e-2)" "unprognostic (1.46e-2)" "unprognostic (7.39e-4)" "unprognostic (1.23e-1)" "unprognostic (1.28e-1)" "unprognostic (1.99e-1)" 0.1 0.1 21.6 0.0 20.6 0.0 0.0 19.0 27.3 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 19.4 31.7 0.0 0.0 0.0 0.0 24.8 38.0 1.2 0.0 0.0 0.6 0.0 23.9 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.1 0.0 0.2 44.7 0.0 0.1 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 20.6 19.0 27.3 19.4 31.7 24.8 38.0 23.9 21.1 44.7 23.1 0.3 0.0 0.0 135.5 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 11.2 0.0 15.4 0.0 2.5 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 6.6 0.0 1.8 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 GALR1 "GALNR, GALNR1" ENSG00000166573 "Galanin receptor 1" P47211 18 77249848-77277900 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.4;brain: 1.9;pituitary gland: 1.4" "Cell type enhanced" "Detected in some" "Early spermatids: 68.1;Enteroendocrine cells: 17.6;Oligodendrocyte precursor cells: 42.7;Respiratory ciliated cells: 11.7" "Cancer enriched" "Detected in single" 6 "glioma: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 5.2" "Low region specificity" "Detected in many" HPA074584 Supported "Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA074584: " "unprognostic (1.65e-1)" "unprognostic (1.56e-2)" "unprognostic (2.85e-1)" "unprognostic (3.00e-1)" "unprognostic (2.11e-1)" "unprognostic (2.77e-3)" "unprognostic (1.31e-2)" "unprognostic (5.34e-3)" "unprognostic (7.33e-3)" "unprognostic (9.49e-2)" "unprognostic (2.18e-1)" 0.1 1.4 0.8 0.1 0.5 0.2 0.1 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.7 1.5 0.0 0.2 0.0 0.0 1.1 1.6 0.0 0.0 0.2 1.4 0.0 0.8 0.2 0.1 0.5 0.0 0.2 0.0 0.1 0.2 0.0 1.3 0.0 0.1 0.1 1.9 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.1 0.8 0.7 1.5 1.1 1.6 0.8 1.3 1.9 0.8 4.2 0.0 3.6 0.0 0.0 0.0 1.1 0.0 0.0 4.2 0.0 0.0 0.6 0.0 0.6 1.8 0.0 0.0 0.0 0.1 0.0 0.0 68.1 0.3 0.1 0.3 17.6 0.0 1.4 0.0 0.0 1.0 0.0 0.3 1.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 8.0 0.0 0.3 0.0 0.0 0.1 0.2 1.0 42.7 0.3 0.0 1.1 0.0 0.0 0.8 0.0 0.1 11.7 0.4 0.0 3.1 0.2 0.1 0.8 0.0 0.0 0.0 0.3 0.0 0.0 1.2 GAPT "C5orf29, FLJ33641" ENSG00000175857 "GRB2 binding adaptor protein, transmembrane" Q8N292 5 58491435-58497090 "Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 16.9;lymphoid tissue: 42.7" "Cell type enhanced" "Detected in some" "B-cells: 84.8;dendritic cells: 160.1;granulocytes: 55.0;Macrophages: 43.0;monocytes: 41.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "eosinophil: 1000.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 1000.3" "Cell line enhanced" "Detected in some" "HEL: 71.5;HL-60: 41.8;NB-4: 43.3;THP-1: 33.7;U-937: 118.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA011048, HPA011070" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA011048: , HPA011070: AB_1848887" "unprognostic (9.79e-2)" "unprognostic (5.67e-3)" "unprognostic (2.39e-2)" "unprognostic (3.26e-2)" "unprognostic (3.36e-2)" "unprognostic (8.09e-4)" "unprognostic (4.32e-1)" "unprognostic (1.23e-3)" "unprognostic (4.14e-2)" "unprognostic (9.47e-3)" "unprognostic (7.28e-2)" "unprognostic (2.93e-1)" "unprognostic (3.52e-3)" "unprognostic (3.74e-2)" "unprognostic (2.42e-2)" "unprognostic (2.33e-2)" "unprognostic (1.40e-2)" 1.7 0.8 0.7 28.5 0.7 16.9 2.3 0.7 1.1 2.7 1.3 2.7 3.7 1.3 1.1 2.1 1.6 5.7 0.7 0.7 1.0 0.8 2.0 4.2 25.3 1.3 1.1 0.4 1.1 1.1 0.6 1.0 1.3 1.8 3.8 0.5 1.9 1.2 0.2 0.8 6.6 4.7 1.0 18.2 3.7 0.7 1.1 6.9 0.6 0.7 42.7 6.0 0.5 1.8 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 71.5 0.2 0.0 0.0 41.8 12.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 43.3 0.0 0.0 0.0 17.7 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 33.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 118.4 0.0 125.5 66.7 1000.3 0.4 46.5 0.5 97.0 0.4 0.4 76.8 97.4 0.3 0.3 82.0 1.4 59.3 205.4 0.3 32.0 0.7 0.7 0.7 1.1 0.7 1.0 1.3 1.1 1.3 1.0 1.1 1.8 0.4 3.2 1.9 0.0 84.8 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.2 0.0 0.6 0.0 0.0 0.0 160.1 0.0 0.0 0.0 1.6 0.0 0.1 0.9 0.0 8.8 0.0 0.0 0.1 0.4 0.5 0.0 55.0 0.0 0.4 0.0 14.3 0.0 0.0 0.0 0.0 19.4 6.0 0.5 0.0 43.0 0.0 1.9 41.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 GFRAL "bA360D14.1, C6orf144, GRAL, UNQ9356" ENSG00000187871 "GDNF family receptor alpha like" Q6UXV0 6 55327469-55402493 "Predicted membrane proteins" Receptor "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047372 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA047372: AB_2680017" "unprognostic (2.31e-1)" 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GHR GHBP ENSG00000112964 "Growth hormone receptor" P10912 5 42423439-42721878 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 84.7;liver: 213.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 53.3;Hepatocytes: 141.3;Inhibitory neurons: 115.7;Oligodendrocyte precursor cells: 181.0" "Group enriched" "Detected in many" 4 "breast cancer: 2.8;liver cancer: 7.6;prostate cancer: 8.1;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HSkMC: 21.2;T-47d: 56.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045339, HPA057705" Enhanced Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" "Secreted to blood" NA NA 2200000 24000000 "Cluster 85: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol, Cytoplasmic bodies" "HPA045339: AB_2679294, HPA057705: AB_2683507" "unprognostic (2.18e-2)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.96e-2)" "unprognostic (3.12e-1)" "unprognostic (1.57e-1)" "prognostic favorable (2.73e-6)" "unprognostic (1.06e-1)" "unprognostic (3.92e-2)" "unprognostic (3.73e-2)" "unprognostic (6.15e-3)" "unprognostic (2.67e-2)" "unprognostic (1.67e-3)" "unprognostic (4.29e-4)" "unprognostic (7.82e-2)" "unprognostic (7.33e-4)" "unprognostic (8.35e-6)" 84.7 5.6 1.8 1.7 2.1 0.2 30.1 1.7 1.7 5.2 2.3 5.8 1.1 4.5 4.6 3.9 5.4 5.2 8.9 1.8 5.6 11.8 213.3 4.0 1.3 1.0 2.0 7.5 2.1 5.5 1.2 4.8 1.4 11.1 5.7 0.4 3.7 4.7 45.7 5.6 4.3 4.0 1.1 4.0 6.1 1.7 3.4 2.3 4.6 11.6 0.9 5.0 5.8 1.4 0.0 0.0 0.6 5.0 3.3 0.7 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.3 4.3 0.0 0.0 2.6 0.0 0.1 0.0 0.6 0.0 0.0 21.2 7.0 0.0 1.0 0.1 0.1 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.3 0.1 3.5 0.6 56.0 0.1 3.0 4.8 2.1 2.6 0.5 0.5 0.0 0.0 0.5 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 2.1 1.7 1.7 1.8 5.6 1.0 2.0 1.4 1.1 3.4 1.4 17.2 0.0 0.5 14.7 0.4 4.7 4.5 17.8 10.2 0.6 9.7 16.0 18.6 1.5 1.9 1.8 0.0 17.4 0.5 2.8 1.9 0.0 5.1 0.5 9.4 4.8 3.0 5.3 53.3 0.2 2.2 23.8 0.5 0.3 0.0 1.1 6.1 141.3 1.9 0.0 115.7 1.9 0.0 3.0 1.8 2.8 18.6 0.7 1.8 36.5 0.0 0.7 0.0 181.0 3.6 0.2 1.7 12.0 0.0 5.2 0.0 9.6 0.6 0.4 13.1 18.7 15.1 0.7 0.3 2.9 3.7 40.2 0.5 49.4 2.2 0.9 GJC2 "CX46.6, CX47, GJA12, SPG44" ENSG00000198835 "Gap junction protein gamma 2" Q5T442 1 228149930-228159826 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 51.3" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 12.5;Oligodendrocytes: 26.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 5.4;SCLC-21H: 2.9;TIME: 2.7" "Region enhanced" "Detected in all" "white matter: 105.5" "Low region specificity" "Detected in all" HPA069619 Supported "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA069619: " "unprognostic (2.67e-1)" "unprognostic (1.81e-2)" "unprognostic (6.42e-2)" "unprognostic (8.19e-3)" "unprognostic (4.24e-1)" "unprognostic (1.57e-1)" "unprognostic (6.94e-2)" "unprognostic (2.56e-1)" "unprognostic (4.99e-2)" "unprognostic (7.09e-2)" "unprognostic (7.88e-3)" "unprognostic (9.67e-2)" "unprognostic (6.09e-3)" "unprognostic (2.53e-2)" "unprognostic (7.36e-2)" "unprognostic (1.54e-1)" "unprognostic (2.02e-1)" 2.9 0.9 13.6 0.6 31.2 0.2 1.7 39.0 20.2 4.2 5.2 5.8 0.2 4.7 0.9 1.4 5.4 0.7 1.7 13.9 19.5 1.3 0.5 2.9 0.6 43.9 31.6 3.8 0.5 0.7 1.4 0.5 38.1 3.0 0.3 0.5 0.8 1.7 0.8 1.7 1.7 1.8 28.1 1.4 2.4 1.2 27.6 0.4 2.0 0.8 0.3 4.2 3.5 51.3 0.2 0.2 0.1 0.3 0.8 0.4 1.0 0.8 0.2 0.3 0.4 0.5 0.7 0.1 5.4 1.5 0.4 0.5 0.2 0.2 0.1 0.2 0.9 0.2 1.4 1.2 1.4 0.0 0.0 0.2 0.1 0.5 0.3 0.7 0.1 1.0 0.6 0.1 0.2 0.3 1.1 0.3 0.3 0.0 1.1 0.2 0.1 0.0 0.4 0.0 2.9 1.7 0.2 0.0 0.2 0.1 0.1 0.2 2.7 0.7 2.1 2.5 0.9 0.1 0.4 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.6 31.2 39.0 20.2 13.9 19.5 43.9 31.6 38.1 28.1 27.6 51.3 2.8 0.0 0.6 0.7 0.2 3.4 1.3 0.6 1.8 2.6 1.3 0.6 1.8 0.0 0.0 0.0 12.5 0.0 0.4 0.2 0.0 0.1 0.2 1.0 1.1 4.3 0.0 0.0 0.8 0.5 0.0 2.2 0.0 1.6 0.0 0.3 3.6 0.0 0.1 3.3 1.1 0.3 0.0 0.6 3.8 0.0 2.5 1.3 1.8 0.0 0.0 0.3 0.0 0.0 26.9 1.1 0.0 4.1 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.6 1.8 0.0 0.0 0.5 1.7 0.0 0.8 0.6 0.3 1.0 GLDN "CLOM, COLM, colmedin, CRG-L2, UNC-122" ENSG00000186417 Gliomedin Q6ZMI3 15 51341655-51408005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 84.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 510.8" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 2.7;MCF7: 1.3;SuSa: 1.8;U-266/70: 3.3;U-266/84: 2.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050873, HPA059441" Uncertain Supported "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 410000 "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "HPA050873: , HPA059441: AB_2684018" "unprognostic (5.04e-2)" "unprognostic (2.57e-2)" "unprognostic (5.15e-5)" "unprognostic (3.21e-3)" "unprognostic (2.82e-2)" "unprognostic (2.33e-1)" "unprognostic (2.07e-4)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (3.30e-2)" "unprognostic (3.15e-1)" "unprognostic (2.14e-2)" "unprognostic (9.89e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-1)" "unprognostic (3.80e-3)" "unprognostic (1.37e-1)" 18.5 2.3 18.1 1.6 51.1 0.7 9.7 35.0 28.6 1.8 0.0 3.5 0.2 0.5 0.5 0.5 1.2 3.4 5.0 15.5 31.2 0.4 0.1 8.7 0.2 47.6 48.9 0.5 0.5 0.4 0.6 3.9 56.4 2.4 6.4 1.3 1.4 0.7 1.0 5.0 0.6 0.6 26.0 2.9 2.1 0.2 41.7 0.1 0.8 0.9 0.2 1.5 1.5 84.8 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 2.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.8 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 1.0 0.0 1.8 0.0 0.5 0.0 0.0 0.0 0.1 0.0 3.3 2.9 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 18.1 51.1 35.0 28.6 15.5 31.2 47.6 48.9 56.4 26.0 41.7 84.8 40.1 0.0 2.6 2.0 0.0 6.2 0.0 0.3 0.0 9.2 0.2 0.3 8.4 0.0 0.1 0.0 0.0 5.2 0.0 47.0 0.0 0.0 0.0 0.0 0.1 3.7 1.2 0.0 7.4 0.0 0.6 7.9 4.6 0.2 0.0 4.5 0.0 0.2 4.9 0.0 17.2 1.7 0.0 14.9 9.5 0.0 0.3 16.1 3.6 42.2 0.0 0.3 0.0 2.0 510.8 0.1 28.6 0.0 0.0 0.1 0.0 0.1 0.9 0.8 0.0 4.7 9.8 0.1 0.1 0.0 4.0 100.4 0.6 0.4 5.1 1.6 GLO1 GLOD1 ENSG00000124767 "Glyoxalase I" Q04760 6 38675925-38703145 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "HMC-1: 2571.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040541, CAB040542, HPA059791" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 1500000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB040541: , CAB040542: , HPA059791: AB_2684126" "unprognostic (4.33e-2)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (1.08e-2)" "unprognostic (3.96e-3)" "unprognostic (2.51e-1)" "prognostic unfavorable (5.21e-4)" "unprognostic (5.09e-2)" "unprognostic (2.10e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (8.71e-2)" "unprognostic (1.20e-2)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (6.21e-2)" 55.4 62.3 69.4 38.9 74.1 31.6 74.2 74.6 83.4 55.9 77.2 51.8 116.3 57.8 110.9 60.0 72.3 41.4 88.9 72.6 76.2 87.2 157.7 66.6 48.4 73.7 72.8 82.8 42.1 106.1 23.2 64.1 75.1 171.4 52.3 100.3 43.2 62.1 154.2 66.6 67.7 61.8 77.9 48.2 48.5 27.9 72.9 50.0 54.8 128.8 60.3 52.4 51.6 77.1 201.6 92.0 257.4 256.7 119.2 213.9 227.0 171.1 161.4 235.4 243.0 224.4 75.3 222.5 132.2 137.5 280.1 129.5 222.5 221.1 295.8 203.8 343.0 329.4 105.7 211.3 178.5 126.7 2571.5 183.9 133.5 223.7 159.0 153.2 258.5 154.9 264.7 143.6 223.3 170.6 199.5 160.5 185.5 179.2 176.7 171.0 311.1 145.8 217.8 149.9 199.3 201.3 120.6 165.4 329.8 175.9 192.4 628.3 107.6 182.0 167.1 159.8 275.9 112.7 227.0 608.6 66.1 322.7 299.6 23.7 20.7 15.3 35.5 33.4 48.0 51.9 35.3 36.7 39.0 51.4 32.7 34.9 2.7 23.5 26.9 60.4 34.1 33.3 69.4 74.1 74.6 83.4 72.6 76.2 73.7 72.8 75.1 77.9 72.9 77.1 69.2 131.4 174.4 26.1 86.3 64.6 112.6 88.2 37.0 56.1 67.7 55.8 133.2 58.6 84.5 90.1 20.9 102.7 68.3 34.1 248.4 132.1 4.5 76.2 58.8 74.3 36.5 83.5 23.9 73.3 323.0 86.0 53.0 67.5 71.4 78.7 161.0 114.0 78.8 69.0 21.9 39.3 99.7 125.7 72.8 6.5 83.9 70.0 104.9 17.8 92.6 190.3 49.4 25.1 24.8 77.3 36.0 109.9 86.4 178.8 103.2 132.2 80.7 65.5 46.0 62.0 70.9 15.0 16.1 77.2 88.2 73.2 62.4 123.7 63.4 130.2 GLP2R ENSG00000065325 "Glucagon like peptide 2 receptor" O95838 17 9822206-9892099 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 12.2;intestine: 13.5;urinary bladder: 11.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Excitatory neurons: 6.4;Leydig cells: 3.1;Rod photoreceptor cells: 23.3" "Cancer enhanced" "Detected in single" "pancreatic cancer: 1.1" "Group enriched" "Detected in many" 6 "basal ganglia: 3.0;cerebral cortex: 3.6;hippocampal formation: 3.2;white matter: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HeLa: 78.1" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.1;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "CAB022690, HPA049244" Supported Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "CAB022690: , HPA049244: AB_2680690" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (2.66e-3)" "unprognostic (2.21e-2)" "unprognostic (3.81e-3)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (5.15e-2)" "unprognostic (7.63e-2)" "unprognostic (7.14e-2)" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (3.40e-8)" "unprognostic (9.53e-5)" "unprognostic (5.51e-2)" "unprognostic (3.92e-1)" "unprognostic (6.48e-3)" 8.1 0.3 0.4 0.7 3.0 0.0 0.8 0.0 3.6 6.0 0.0 13.5 9.9 1.2 0.0 0.7 1.6 12.2 0.6 3.2 0.0 0.3 2.7 1.0 0.6 0.0 0.2 0.4 1.6 0.0 0.0 1.1 0.0 0.1 6.0 3.4 0.0 0.1 0.1 0.1 8.2 1.9 0.0 0.1 3.7 0.4 0.0 0.1 0.2 0.2 0.2 11.8 1.5 1.7 0.0 16.6 0.0 0.0 0.8 0.0 0.8 0.0 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 2.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 78.1 0.6 1.0 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.0 0.0 3.6 3.2 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 6.4 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.4 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.5 0.0 1.5 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 23.3 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GLUL GLNS ENSG00000135821 "Glutamate-ammonia ligase" P15104 1 182378098-182392206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Ligase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1443.6" "Group enriched" "Detected in all" 4 "Late spermatids: 8544.2;Muller glia cells: 6247.0" "Cancer enhanced" "Detected in all" "liver cancer: 365.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 656.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 656.8" "Cell line enhanced" "Detected in many" "ASC diff: 1150.8;ASC TERT1: 807.6;HSkMC: 702.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007316, HPA007571, CAB008636" Approved Supported "Plasma membrane,Mitochondria,Cytosol" NA NA 150000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Mitochondria, Cytosol" "Plasma membrane" "CAB008636: AB_1616669, HPA007316: AB_888438, HPA007571: AB_1078980" "prognostic favorable (4.81e-4)" "unprognostic (1.52e-3)" "unprognostic (3.89e-1)" "unprognostic (3.32e-1)" "unprognostic (1.25e-1)" "unprognostic (9.52e-2)" "unprognostic (7.58e-2)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (8.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.17e-1)" "unprognostic (1.38e-2)" "unprognostic (4.17e-2)" "unprognostic (2.06e-1)" "unprognostic (5.55e-2)" "unprognostic (4.53e-3)" 753.5 76.0 694.3 156.9 746.5 232.9 573.5 717.5 1237.1 161.4 583.2 157.8 24.4 116.7 115.7 218.7 224.3 105.4 129.7 676.6 764.7 65.3 280.7 221.7 75.2 891.0 783.7 303.0 204.7 32.3 70.5 176.6 767.0 103.4 92.5 891.1 233.5 96.0 1443.6 231.4 148.2 124.1 725.0 216.4 648.2 87.1 811.4 97.0 257.4 472.0 103.2 185.5 292.0 810.4 26.4 10.8 117.2 0.2 1150.8 807.6 86.0 44.1 141.7 25.9 23.4 64.1 26.7 22.4 46.3 85.5 23.8 59.3 51.8 309.4 21.5 61.2 143.3 296.5 47.6 124.8 61.1 132.6 227.2 702.1 363.3 32.9 384.6 39.1 52.8 71.7 254.3 13.3 92.6 15.0 208.2 126.5 87.3 36.8 55.0 74.3 31.3 38.6 45.8 114.0 79.7 52.5 12.4 157.3 17.4 93.3 153.1 165.9 39.7 0.9 1.9 0.8 10.1 4.8 3.4 0.4 22.3 73.9 5.0 396.5 153.4 409.4 42.3 145.8 17.6 11.5 29.9 35.5 80.0 17.8 15.3 25.3 656.8 27.2 130.5 43.7 13.0 172.0 694.3 746.5 717.5 1237.1 676.6 764.7 891.0 783.7 767.0 725.0 811.4 810.4 127.8 125.0 173.8 599.4 37.6 134.7 533.8 1190.7 260.0 105.6 166.6 99.1 216.2 171.6 855.3 82.8 52.1 161.7 113.4 118.3 74.3 124.2 1491.3 140.2 150.0 191.5 325.9 319.7 3.4 116.6 65.9 404.4 388.4 124.6 786.3 88.0 152.8 597.1 798.0 43.7 22.0 256.7 451.6 907.2 614.1 8544.2 487.4 687.4 136.9 74.9 112.7 6247.0 42.2 38.2 330.0 108.1 105.3 375.0 38.7 421.0 10.3 46.6 569.9 176.0 92.1 481.5 218.5 48.2 63.6 186.5 128.3 235.3 108.6 53.3 173.3 1420.5 GNAI2 "GIP, GNAI2B" ENSG00000114353 "G protein subunit alpha i2" P04899 3 50226292-50259362 "Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 656.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007704 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 4000000 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Cytosol "Nucleoplasm, Plasma membrane" "HPA007704: AB_1849230" "prognostic favorable (1.03e-4)" "unprognostic (3.89e-1)" "unprognostic (3.35e-2)" "unprognostic (8.40e-3)" "unprognostic (2.58e-1)" "unprognostic (2.32e-2)" "unprognostic (2.59e-2)" "unprognostic (3.23e-1)" "unprognostic (1.08e-3)" "unprognostic (6.01e-2)" "unprognostic (7.00e-3)" "unprognostic (1.12e-1)" "unprognostic (6.24e-3)" "unprognostic (1.44e-1)" "unprognostic (4.30e-2)" "unprognostic (4.33e-2)" "unprognostic (1.38e-1)" 210.2 100.3 155.2 217.9 167.3 367.1 152.8 166.3 181.6 146.0 120.2 142.1 69.9 141.7 66.9 124.4 136.9 152.5 157.1 144.3 184.6 79.4 126.5 214.5 251.3 199.8 170.2 147.7 64.1 66.9 99.2 241.8 194.8 103.6 64.3 35.6 71.9 156.9 69.3 87.0 103.0 154.0 173.6 262.1 73.6 69.6 173.3 160.3 101.3 89.4 170.4 169.7 108.4 193.2 128.2 63.0 186.3 197.6 220.7 277.5 35.5 271.1 399.6 354.9 361.1 70.4 173.2 149.1 119.2 567.0 193.4 100.1 132.8 350.3 222.8 331.2 50.9 364.8 158.0 110.2 219.8 329.2 479.8 270.3 152.9 319.1 129.8 289.6 837.8 124.1 26.1 307.1 357.5 155.7 313.6 433.0 109.7 59.0 302.4 185.0 89.8 219.7 232.6 130.9 48.4 86.1 189.5 57.1 124.4 150.4 94.3 346.1 792.3 330.9 187.5 309.2 274.7 199.4 278.3 127.0 373.6 466.9 398.1 16.6 59.3 113.7 33.7 80.9 20.2 28.8 26.8 34.3 57.3 26.1 20.2 25.8 145.2 23.5 74.5 47.2 34.0 27.3 155.2 167.3 166.3 181.6 144.3 184.6 199.8 170.2 194.8 173.6 173.3 193.2 656.8 41.7 32.1 25.1 119.5 56.7 59.7 32.3 45.5 29.0 61.6 83.8 22.9 55.8 26.6 44.1 14.6 79.5 311.4 11.7 5.9 124.3 203.3 57.8 115.7 340.3 92.2 52.1 12.4 60.5 84.4 101.9 21.9 71.8 89.9 150.0 221.3 79.7 336.0 6.7 14.8 24.6 18.3 342.7 291.7 302.0 90.7 386.1 83.6 58.1 356.6 292.6 151.4 26.7 45.4 160.3 40.9 95.5 104.8 46.1 30.3 24.5 24.4 21.9 52.6 85.3 163.1 16.6 22.6 37.6 62.9 116.4 164.9 156.3 20.5 70.1 GNAS "GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI" ENSG00000087460 "GNAS complex locus" "O95467, P63092, P84996, Q5JWF2" 20 58839718-58911192 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transducer "Cancer-related genes, Cushing syndrome, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 1886.1;Late spermatids: 1756.9;Skeletal myocytes: 1998.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010337, HPA018122, HPA027478, HPA028386" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Plasma membrane, Cytosol" "CAB010337: AB_631538, HPA018122: AB_1849236, HPA027478: AB_10599284, HPA028386: AB_10601983" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (3.90e-2)" "unprognostic (4.77e-2)" "unprognostic (8.37e-3)" "unprognostic (2.82e-2)" "unprognostic (4.53e-3)" "unprognostic (8.01e-2)" "unprognostic (4.29e-2)" "prognostic favorable (8.76e-4)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (5.24e-3)" "unprognostic (1.61e-1)" "unprognostic (8.25e-2)" "unprognostic (1.36e-1)" 784.8 1215.3 1564.4 512.6 1524.7 887.4 578.9 1413.1 1768.3 828.5 1373.3 657.1 492.4 611.4 1253.8 883.1 742.9 672.7 1990.6 1557.3 2716.9 625.0 651.1 640.3 769.2 1710.5 1949.4 766.5 1917.7 1799.4 1153.6 884.6 1963.4 577.3 607.3 731.2 2943.9 594.4 2400.4 526.8 527.3 782.4 1598.4 606.6 587.1 357.9 1882.0 854.4 3432.2 2813.1 800.0 687.1 239.3 1483.9 215.6 897.3 1501.9 663.3 2691.8 1822.3 1200.1 1219.1 1635.0 1937.3 1201.8 2480.5 1446.7 911.9 1670.3 2314.3 1305.6 976.1 1499.0 2195.3 1540.9 401.4 784.6 984.9 1651.7 2232.7 1420.7 641.6 483.0 1566.4 1113.6 875.1 1399.1 1561.0 1669.7 1100.6 692.0 1294.6 1319.1 4131.0 1759.5 1452.8 487.9 214.0 894.4 1436.7 1287.3 1589.4 2165.5 1315.8 1818.3 3853.2 2157.6 2117.1 1354.2 1921.8 1570.0 1581.7 1343.3 2210.2 1477.0 688.5 1452.3 1314.0 993.3 1583.2 900.0 473.7 1107.1 217.9 96.7 114.2 68.9 127.3 80.0 103.2 73.4 74.8 129.2 93.6 65.8 82.6 103.4 95.6 150.3 174.9 92.7 100.9 1564.4 1524.7 1413.1 1768.3 1557.3 2716.9 1710.5 1949.4 1963.4 1598.4 1882.0 1483.9 982.6 221.2 258.8 192.0 310.8 130.4 182.0 130.0 205.5 397.8 465.6 684.4 1025.3 237.4 212.2 261.1 56.3 832.6 390.8 357.3 444.1 233.9 734.9 487.7 515.7 518.3 463.1 252.1 232.5 228.9 342.0 380.9 196.3 685.0 138.6 542.3 380.1 256.4 379.1 1886.1 439.7 327.2 181.0 380.4 405.7 1756.9 265.3 437.1 222.3 236.1 204.0 1367.2 137.0 194.5 166.6 339.9 300.0 197.1 309.7 268.1 273.7 153.6 218.0 222.0 210.4 1998.0 560.4 226.0 73.6 240.5 117.8 1211.7 301.8 860.9 304.4 316.5 GNB2 ENSG00000172354 "G protein subunit beta 2" P62879 7 100673567-100679174 "Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010032, HPA040736" Approved Supported "Plasma membrane" NA NA 940000 "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "CAB010032: AB_2263466, HPA040736: AB_2677106" "unprognostic (1.55e-1)" "unprognostic (5.76e-2)" "unprognostic (1.01e-3)" "unprognostic (2.76e-1)" "unprognostic (1.11e-2)" "unprognostic (1.94e-1)" "unprognostic (3.68e-3)" "unprognostic (3.52e-1)" "unprognostic (6.58e-2)" "unprognostic (2.54e-1)" "unprognostic (9.79e-3)" "unprognostic (1.70e-1)" "unprognostic (3.75e-2)" "unprognostic (1.24e-1)" "unprognostic (3.19e-1)" "unprognostic (5.29e-2)" "unprognostic (2.98e-1)" 198.4 211.0 131.4 128.3 137.3 207.5 188.0 112.3 179.6 209.4 103.8 168.0 103.2 182.4 63.7 328.4 179.8 105.5 175.9 130.2 138.1 186.1 185.8 210.1 107.9 140.3 130.1 175.3 184.8 98.9 203.3 107.4 123.6 183.0 83.6 20.1 190.8 113.6 175.9 295.5 143.5 113.5 126.3 225.9 172.4 92.9 137.6 90.2 144.8 90.2 105.7 165.2 217.7 120.7 358.6 268.6 222.7 272.5 169.8 199.9 194.3 208.4 288.4 294.3 241.7 205.3 333.7 157.7 216.0 311.3 332.2 243.0 177.7 312.6 103.0 216.9 152.1 120.8 198.7 171.3 282.4 157.7 254.5 259.5 291.1 304.2 244.6 237.6 343.6 132.5 228.6 303.3 270.4 980.0 249.5 450.3 173.5 225.1 290.1 234.3 136.3 253.8 235.4 291.3 241.0 380.1 278.0 449.2 201.3 125.3 192.4 192.1 325.8 313.8 346.8 619.2 266.6 88.8 111.9 240.9 237.1 349.7 443.6 27.6 28.6 70.9 17.5 42.7 16.2 13.6 17.9 15.4 28.1 18.1 11.8 12.4 117.2 15.4 35.9 23.8 23.5 12.5 131.4 137.3 112.3 179.6 130.2 138.1 140.3 130.1 123.6 126.3 137.6 120.7 138.1 57.7 97.0 16.0 104.1 151.8 159.3 72.9 148.0 10.4 105.4 106.0 35.0 100.1 55.5 84.6 4.2 172.4 89.4 285.4 162.4 163.7 32.6 133.5 106.8 136.5 180.4 127.7 12.7 218.7 312.1 117.6 135.1 127.2 44.4 97.6 126.0 69.9 264.4 72.3 10.8 211.2 75.3 198.6 198.8 20.1 144.8 193.5 140.5 15.9 160.8 128.2 96.8 5.0 6.9 257.1 285.6 130.1 122.5 226.5 162.3 107.0 68.3 8.5 65.7 62.0 162.2 34.3 69.6 240.7 194.8 293.9 117.8 88.1 192.2 259.5 GNB4 ENSG00000114450 "G protein subunit beta 4" Q9HAV0 3 179396088-179451476 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Transducer "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 81.1;Kupffer cells: 98.1;Macrophages: 66.8;Microglial cells: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 143.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018383, CAB018737, HPA040736" Supported Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB018383: AB_631542, CAB018737: AB_640712, HPA040736: AB_2677106" "unprognostic (2.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.62e-1)" "unprognostic (1.01e-1)" "unprognostic (5.97e-3)" "unprognostic (2.12e-1)" "unprognostic (1.44e-2)" "unprognostic (8.28e-2)" "unprognostic (1.16e-1)" "unprognostic (3.44e-1)" "unprognostic (1.56e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (1.90e-3)" "unprognostic (3.13e-2)" "unprognostic (8.90e-2)" "unprognostic (2.80e-3)" 14.9 6.3 8.7 21.9 19.2 33.7 12.4 7.3 11.2 11.5 2.9 9.5 5.9 9.2 3.7 21.9 7.0 15.2 13.9 9.6 8.7 5.9 7.8 16.0 17.7 15.5 8.5 5.8 2.8 2.7 3.0 21.8 14.5 4.5 8.6 2.0 4.7 4.0 3.1 34.1 6.4 23.5 14.5 18.1 7.4 4.3 10.9 7.9 6.3 5.7 11.5 13.2 6.8 19.7 33.4 15.4 37.7 0.8 23.8 41.5 44.1 46.7 33.1 54.1 61.3 0.8 3.7 61.6 9.9 54.3 49.7 0.6 36.4 43.1 56.7 143.6 29.2 71.3 54.9 0.7 23.4 62.3 16.2 32.9 6.6 42.4 21.6 12.0 59.3 13.7 18.7 0.8 42.8 1.3 32.8 24.3 18.9 0.2 19.3 61.4 49.2 25.3 34.9 1.9 7.0 20.5 37.5 33.0 61.1 23.0 67.5 26.1 45.3 45.1 27.4 13.6 61.6 0.3 0.9 0.8 24.7 52.8 35.4 5.6 21.3 11.0 0.2 27.8 0.1 6.7 0.4 0.3 24.9 13.6 0.4 0.3 14.5 3.4 23.5 12.8 0.6 8.8 8.7 19.2 7.3 11.2 9.6 8.7 15.5 8.5 14.5 14.5 10.9 19.7 40.0 25.6 12.8 17.9 20.1 18.7 1.8 2.5 13.6 1.7 14.3 12.3 15.6 0.0 12.3 3.7 6.2 13.8 11.5 0.1 3.9 1.1 1.2 15.6 22.9 42.9 0.0 22.9 18.6 1.6 18.7 26.6 3.6 10.8 10.8 16.2 53.2 0.9 81.1 1.7 18.4 0.0 2.0 98.1 17.4 1.4 10.2 66.8 14.2 91.8 59.9 0.8 2.1 11.6 7.7 2.8 0.0 15.8 8.1 2.6 0.2 0.2 11.3 4.0 26.3 9.9 41.8 2.3 16.8 23.4 25.4 4.1 2.9 14.7 0.0 1.3 GP6 GPVI ENSG00000088053 "Glycoprotein VI platelet" Q9HCN6 19 55013705-55038264 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Early spermatids: 14.3;Excitatory neurons: 9.9;Inhibitory neurons: 10.2;Late spermatids: 8.7;Macrophages: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HEL: 9.4;K-562: 4.1;U-2 OS: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047611, HPA066482" Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA 44000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "HPA047611: , HPA066482: AB_2685674" "unprognostic (3.06e-3)" "unprognostic (4.58e-2)" "unprognostic (1.74e-5)" "unprognostic (1.94e-1)" "unprognostic (1.20e-1)" "unprognostic (3.52e-2)" "unprognostic (7.50e-4)" "unprognostic (2.81e-1)" "unprognostic (1.00e-1)" "unprognostic (4.18e-2)" "unprognostic (3.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.53e-1)" "unprognostic (2.62e-1)" "unprognostic (3.32e-2)" "unprognostic (5.44e-3)" "unprognostic (2.70e-2)" 0.1 0.0 0.1 0.0 0.1 0.9 0.2 0.7 0.5 0.5 0.0 0.2 0.0 0.2 0.0 1.4 0.4 0.0 0.7 0.1 0.0 0.5 0.2 0.9 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.1 0.1 0.4 0.0 0.2 0.4 0.1 0.1 1.2 0.1 0.0 0.0 0.9 0.2 2.7 0.0 0.0 0.4 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.1 0.3 9.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 2.5 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.2 0.1 0.1 0.7 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.3 0.3 0.0 2.0 0.3 0.4 0.7 1.5 0.3 0.0 6.2 0.1 0.4 0.7 0.0 0.1 14.3 1.4 0.4 1.2 0.0 0.0 9.9 0.4 0.3 0.6 0.0 2.2 1.3 0.8 3.3 0.2 0.1 3.3 10.2 0.0 0.0 0.8 0.2 8.7 0.3 10.3 0.0 1.0 0.3 0.4 2.1 1.5 1.5 0.2 0.1 0.0 0.0 0.4 0.1 0.0 1.9 2.6 0.0 0.4 0.2 1.4 1.2 0.0 0.1 0.5 0.4 0.0 0.3 0.7 GPC1 glypican ENSG00000063660 "Glypican 1" P35052 2 240435663-240468076 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 226.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 199.8;Syncytiotrophoblasts: 102.7;Urothelial cells: 110.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030571, HPA070449" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 9500000 "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA030571: AB_10602322, HPA070449: " "unprognostic (1.22e-2)" "unprognostic (2.53e-2)" "prognostic unfavorable (5.78e-5)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.95e-1)" "unprognostic (1.83e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (1.00e-2)" "unprognostic (2.15e-1)" "unprognostic (5.08e-3)" "unprognostic (2.28e-1)" "unprognostic (4.38e-1)" "unprognostic (1.91e-1)" "unprognostic (4.40e-2)" "unprognostic (2.92e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-2)" 36.8 78.5 42.8 9.0 37.0 0.4 30.7 25.3 64.4 44.5 3.1 36.7 5.8 37.1 9.3 88.4 30.8 8.5 145.2 41.7 28.5 47.6 35.7 21.9 1.4 29.2 30.4 45.1 25.8 9.8 55.7 29.0 26.3 67.8 3.5 5.0 35.2 22.5 134.2 226.0 17.4 16.4 11.3 15.6 23.0 48.7 46.0 9.1 15.7 35.3 6.6 35.1 62.3 24.8 69.0 92.9 21.6 56.7 64.3 61.5 87.3 161.5 78.8 18.3 21.2 33.3 74.9 1.8 21.8 172.0 100.1 186.0 11.7 114.7 3.8 33.3 9.8 0.1 80.7 41.7 92.2 1.6 6.2 54.3 73.4 41.2 21.3 38.1 9.7 3.4 0.4 3.3 47.5 36.0 1.3 0.6 33.7 7.7 20.5 12.3 98.2 16.1 15.0 109.6 21.5 14.4 105.7 91.9 10.1 19.3 29.1 7.0 45.6 97.3 162.3 46.9 67.8 0.7 0.4 0.8 69.4 1.7 111.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.8 37.0 25.3 64.4 41.7 28.5 29.2 30.4 26.3 11.3 46.0 24.8 1.2 16.0 6.1 45.7 0.7 45.9 69.6 62.2 56.3 22.4 8.3 18.2 53.2 21.5 34.0 25.8 2.1 73.7 0.3 3.7 7.9 27.8 0.9 6.2 24.7 2.8 0.0 0.0 53.0 10.8 199.8 21.0 1.5 8.9 4.5 49.4 11.0 26.3 9.1 25.2 45.0 7.0 16.2 0.6 7.7 3.8 19.0 1.2 35.6 5.6 1.6 24.9 1.0 18.6 8.9 17.6 0.9 7.5 0.9 67.0 0.5 2.3 30.2 6.4 26.3 33.9 38.2 2.2 9.9 44.8 46.2 102.7 1.9 14.5 3.6 110.5 GPC3 "DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1" ENSG00000147257 "Glypican 3" P51654 X 133535745-133985594 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 574.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 65.1;Extravillous trophoblasts: 61.0;Fibroblasts: 404.2;Muller glia cells: 88.9;Syncytiotrophoblasts: 148.6" "Cancer enriched" "Detected in all" 4 "liver cancer: 269.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.8" "Group enriched" "Detected in some" 5 "HAP1: 514.3;Hep G2: 1825.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006316 Supported "Plasma membrane" NA NA 27000 "Cluster 32: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA006316: AB_1078994" "unprognostic (2.06e-1)" "unprognostic (2.36e-1)" "unprognostic (9.51e-2)" "unprognostic (4.17e-2)" "unprognostic (1.78e-1)" "unprognostic (1.46e-1)" "unprognostic (6.10e-2)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (3.92e-3)" "unprognostic (6.06e-2)" "unprognostic (1.71e-1)" "unprognostic (3.81e-3)" "prognostic unfavorable (4.83e-4)" "unprognostic (1.43e-1)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" 99.9 22.8 0.5 3.5 1.0 0.0 61.8 0.5 0.3 11.8 0.2 6.5 1.6 9.2 41.1 6.7 13.9 13.7 24.5 0.3 4.0 87.0 5.1 122.9 2.5 1.9 3.1 15.5 21.2 4.1 47.0 574.9 3.0 8.3 4.1 6.2 13.7 9.2 4.5 18.0 5.6 7.3 1.7 3.7 13.6 2.8 2.0 8.0 22.4 28.6 10.9 14.6 9.3 1.0 0.0 0.0 21.8 1.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 154.0 0.0 0.0 0.1 0.1 0.0 0.0 514.3 0.4 0.0 0.0 22.6 0.0 0.9 1825.2 0.3 0.0 0.5 12.9 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.5 0.1 132.1 0.1 0.0 0.0 0.0 0.1 122.4 6.1 15.3 40.3 0.0 0.0 0.4 233.8 0.5 23.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.8 1.2 0.0 0.7 0.0 0.0 0.0 0.1 0.5 1.0 0.5 0.3 0.3 4.0 1.9 3.1 3.0 1.7 2.0 1.0 28.5 0.0 1.7 0.3 1.0 10.5 4.8 17.0 0.0 0.4 5.0 10.4 0.5 1.5 20.0 5.5 0.0 65.1 0.8 0.5 19.6 0.3 0.9 0.2 0.4 1.8 1.8 0.0 2.5 1.6 61.0 404.2 0.5 1.5 0.0 1.0 2.2 0.0 26.7 0.0 2.5 3.1 2.0 0.0 6.1 2.4 10.5 1.0 3.6 23.4 0.0 88.9 0.0 3.5 1.4 1.7 2.6 3.0 0.4 2.7 1.2 40.7 24.3 3.1 0.0 21.7 21.3 6.9 7.1 0.2 4.0 148.6 1.1 7.6 4.1 0.6 GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 331.0;Late spermatids: 1127.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" No No 86000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB018655: AB_2112653, CAB040563: , HPA024305: AB_1849922, HPA052171: AB_2681748" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.38e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-3)" "unprognostic (1.95e-2)" "unprognostic (8.52e-3)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.93e-2)" "unprognostic (2.75e-1)" "unprognostic (3.24e-3)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (2.60e-3)" "unprognostic (2.88e-2)" 196.9 283.2 83.4 74.5 101.9 222.8 129.0 67.7 130.5 95.0 84.8 162.9 113.7 92.4 27.2 197.8 88.8 87.1 407.2 108.5 73.6 196.8 222.6 91.2 66.4 73.5 58.5 97.0 84.2 166.3 147.2 47.5 69.3 94.4 84.3 156.1 105.1 61.0 416.6 120.1 126.5 78.4 34.0 102.2 122.5 95.9 83.2 50.1 100.8 374.6 76.0 147.9 121.5 95.8 572.9 596.1 58.7 433.3 167.5 121.9 134.1 183.4 132.4 206.3 253.7 314.9 169.6 303.5 311.4 177.9 149.1 343.7 337.7 437.0 259.4 461.0 105.1 382.1 252.3 310.8 108.4 517.6 259.3 173.7 136.6 289.0 132.7 273.3 209.3 230.5 210.3 261.8 140.2 319.2 245.5 133.5 158.0 421.3 174.6 242.7 149.1 649.4 254.1 275.4 304.9 185.8 331.9 634.3 131.7 100.5 144.4 161.7 171.9 80.8 185.5 256.7 312.8 535.5 383.7 318.4 287.4 372.3 170.6 188.8 93.2 331.3 80.4 141.2 99.1 59.9 73.7 93.1 101.0 50.5 61.8 72.8 7.4 58.0 180.3 31.6 83.4 123.4 83.4 101.9 67.7 130.5 108.5 73.6 73.5 58.5 69.3 34.0 83.2 95.8 34.2 28.9 40.0 98.9 43.8 25.9 30.1 104.5 42.7 98.8 34.1 27.2 232.5 42.9 51.4 57.0 75.0 44.5 41.6 76.7 115.4 101.7 331.0 35.9 41.2 38.0 63.7 46.7 121.8 66.9 69.2 47.1 109.1 58.0 23.4 36.1 42.8 89.5 89.6 237.2 127.2 75.8 50.8 52.9 40.5 1127.2 37.0 58.1 35.6 17.8 44.4 32.6 23.7 43.7 87.7 77.6 39.4 30.5 77.1 31.5 111.8 103.0 33.1 68.3 19.7 44.3 65.0 7.8 22.3 139.1 32.8 39.3 64.3 74.8 126.9 37.2 GPR1 ENSG00000183671 "G protein-coupled receptor 1" P46091 2 206175316-206218047 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.2" "Group enriched" "Detected in some" 6 "Extravillous trophoblasts: 12.3;Granulosa cells: 42.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 24.7;HHSteC: 133.9;hTCEpi: 61.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA010525 Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Nucleoplasm, Vesicles" "HPA010525: AB_1078919" "unprognostic (5.32e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" "unprognostic (2.25e-2)" "unprognostic (3.27e-5)" "unprognostic (1.36e-1)" "unprognostic (4.00e-3)" "unprognostic (1.49e-2)" "unprognostic (7.89e-2)" "unprognostic (9.94e-2)" "unprognostic (3.42e-3)" "unprognostic (5.65e-2)" "unprognostic (4.29e-4)" "unprognostic (8.48e-4)" "unprognostic (1.21e-1)" "unprognostic (2.68e-2)" "unprognostic (3.06e-3)" 1.5 2.7 0.1 0.2 0.9 0.0 0.7 0.5 0.3 2.6 12.2 0.3 0.1 0.5 0.2 4.5 0.5 1.2 1.6 0.6 0.3 0.4 0.0 0.2 0.8 0.0 0.0 1.3 0.0 0.4 0.2 3.9 0.0 0.2 0.3 0.7 0.9 0.1 0.7 4.8 0.3 1.0 0.0 0.0 0.1 0.9 0.2 0.0 0.3 2.4 0.3 1.0 5.6 0.0 2.2 0.2 1.8 0.0 0.4 7.5 0.6 14.4 24.7 8.8 7.4 0.0 0.0 0.0 0.8 7.3 0.6 0.2 0.7 0.0 2.9 0.0 0.3 0.0 4.2 0.0 133.9 0.0 0.0 5.5 61.8 12.5 20.0 10.2 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 6.9 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.3 6.1 2.9 0.0 0.0 1.6 0.1 0.0 0.3 10.5 4.8 12.5 1.1 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.5 0.3 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.6 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.0 12.3 4.5 0.0 0.0 0.0 42.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.9 1.2 0.0 0.0 0.8 1.0 0.7 0.5 0.0 0.0 0.4 GPR148 PGR6 ENSG00000173302 "G protein-coupled receptor 148" Q8TDV2 2 130729070-130730336 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046655, HPA060527" Uncertain Supported "Plasma membrane" NA NA "Plasma membrane" "HPA046655: , HPA060527: AB_2684307" "unprognostic (7.16e-4)" "unprognostic (3.38e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.2 0.3 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPR156 "GABABL, PGR28" ENSG00000175697 "G protein-coupled receptor 156" Q8NFN8 3 120164645-120285222 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 2.7" "Group enriched" "Detected in some" 4 "Astrocytes: 15.0;Early spermatids: 8.3;Late spermatids: 17.9;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 1.3;PC-3: 1.3;SiHa: 3.5;U-2 OS: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA028642, HPA028644" Uncertain Supported "Plasma membrane" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 20: HeLa - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA028642: AB_10599711, HPA028644: AB_10600441" "unprognostic (2.85e-3)" "unprognostic (1.02e-1)" "unprognostic (3.53e-3)" "unprognostic (2.02e-3)" "unprognostic (1.07e-1)" "unprognostic (3.79e-1)" "unprognostic (2.62e-4)" "unprognostic (2.03e-1)" "unprognostic (4.54e-4)" "unprognostic (5.03e-2)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (4.03e-5)" "unprognostic (2.43e-2)" "unprognostic (3.43e-2)" "unprognostic (4.91e-3)" "unprognostic (6.71e-2)" 0.0 0.0 0.3 0.1 0.3 0.0 0.3 0.0 0.2 0.2 0.1 0.0 0.0 0.4 0.0 0.2 1.0 0.1 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.3 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.7 0.4 0.0 0.0 0.0 0.4 0.3 0.0 0.0 2.7 0.1 0.3 0.0 0.3 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.5 0.0 0.2 0.0 0.3 1.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.3 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 3.5 0.0 0.4 0.1 0.4 0.0 0.1 0.1 1.9 0.0 0.1 0.4 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.2 0.1 0.3 0.3 0.1 0.3 0.1 0.3 0.0 0.0 0.0 15.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.3 0.3 0.2 0.0 0.0 0.0 1.5 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 17.9 0.0 0.1 0.0 1.0 0.0 1.3 0.0 13.0 2.9 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.1 0.6 1.4 0.0 0.0 0.1 0.0 0.3 0.0 0.0 GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037995-170085392 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 107.9;parathyroid gland: 216.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 194.8;Proximal enterocytes: 362.1;Proximal tubular cells: 151.4;Rod photoreceptor cells: 153.2;Undifferentiated cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 123.9;SK-BR-3: 95.8;THP-1: 197.2;U-266/70: 206.2;U-266/84: 127.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006970 Approved Supported "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA006970: AB_1849275" "unprognostic (1.70e-1)" "unprognostic (5.08e-3)" "unprognostic (2.96e-2)" "unprognostic (2.39e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (5.21e-2)" "prognostic favorable (1.21e-4)" "unprognostic (5.71e-3)" "unprognostic (1.35e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "prognostic favorable (4.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (1.43e-1)" "prognostic favorable (3.61e-4)" 12.2 1.7 0.7 15.9 1.0 107.9 22.5 1.0 1.6 11.2 0.9 72.0 73.8 5.8 57.9 2.9 5.4 18.6 1.0 0.6 0.7 59.8 4.1 15.0 27.9 1.4 0.9 0.6 18.4 216.6 1.4 4.1 1.1 26.7 72.6 104.7 19.3 6.3 1.3 1.2 98.6 4.4 0.8 25.2 43.0 5.2 0.9 9.5 6.7 2.7 30.4 26.8 1.0 1.2 64.2 1.5 0.3 0.5 0.3 0.4 15.6 0.4 0.5 0.4 1.9 11.7 8.1 29.4 12.9 0.6 4.0 0.7 8.8 0.5 1.0 45.9 17.7 19.1 1.0 24.3 0.2 38.2 24.8 0.2 0.9 2.0 2.3 2.8 1.4 13.7 6.4 73.9 0.4 41.5 2.9 8.4 10.3 39.1 2.4 5.3 1.1 123.9 32.3 86.8 6.1 1.8 0.8 95.8 4.5 8.2 55.9 197.2 1.9 0.2 0.4 7.1 4.8 206.2 127.9 51.4 0.8 40.3 2.8 2.9 1.1 9.3 0.5 0.4 1.0 8.0 1.0 0.4 2.4 12.3 3.0 1.1 11.3 0.4 0.2 3.2 0.3 1.2 0.7 1.0 1.0 1.6 0.6 0.7 1.4 0.9 1.1 0.8 0.9 1.2 35.2 9.6 51.1 0.7 25.9 0.4 3.2 4.1 0.0 9.5 48.5 18.3 1.0 28.6 22.7 62.5 39.6 3.1 11.6 88.9 54.8 10.3 33.7 20.6 4.4 8.7 194.8 0.4 1.5 72.0 21.1 1.0 50.0 54.0 1.3 0.1 20.0 0.9 7.4 15.2 0.6 133.9 18.3 11.7 11.2 36.3 0.6 17.0 28.4 7.5 62.3 16.6 0.0 1.0 0.9 60.3 118.6 0.4 56.8 25.4 362.1 151.4 27.9 153.2 0.0 0.8 1.4 7.4 13.1 0.9 0.9 27.2 4.2 1.2 199.7 35.5 GPR174 FKSG79 ENSG00000147138 "G protein-coupled receptor 174" Q9BXC1 X 79144688-79175318 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 16.9" "Cell type enhanced" "Detected in some" "B-cells: 6.6;dendritic cells: 30.6;Plasma cells: 4.2;T-cells: 18.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "JURKAT: 42.3;MOLT-4: 75.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041025, HPA058306" Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "Vesicles, Centriolar satellite" "HPA041025: AB_10794260, HPA058306: " "unprognostic (6.38e-3)" "unprognostic (9.87e-3)" "unprognostic (4.36e-2)" "unprognostic (1.18e-2)" "unprognostic (1.84e-1)" "unprognostic (8.48e-4)" "unprognostic (7.12e-2)" "unprognostic (1.05e-2)" "unprognostic (1.75e-1)" "unprognostic (2.02e-1)" "unprognostic (2.46e-1)" "unprognostic (1.05e-1)" "unprognostic (6.53e-5)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "unprognostic (1.78e-2)" 0.8 0.4 0.5 6.9 0.3 2.5 0.9 0.6 0.6 0.4 0.3 1.0 2.0 0.5 0.6 0.3 0.3 1.1 0.3 0.4 0.4 0.5 1.0 1.9 15.2 0.7 0.5 0.2 0.1 0.1 0.1 0.2 0.7 0.7 1.6 0.2 1.5 0.1 0.2 0.2 3.6 0.3 0.3 8.1 2.1 0.1 0.4 16.9 0.9 0.1 10.4 1.4 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.3 0.0 1.2 0.0 0.0 75.1 0.1 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.2 0.0 0.0 0.0 6.5 0.0 3.6 3.6 2.0 1.2 2.5 4.8 6.1 0.1 2.6 4.2 4.9 0.3 4.6 5.5 1.0 4.8 1.6 0.5 0.3 0.6 0.6 0.4 0.4 0.7 0.5 0.7 0.3 0.4 0.5 0.7 0.0 2.4 0.0 6.6 0.1 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.6 1.8 0.0 0.0 30.6 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 18.5 0.1 0.0 0.0 GPR20 ENSG00000204882 "G protein-coupled receptor 20" Q99678 8 141356470-141367286 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 4 "Sertoli cells: 72.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "intermediate monocyte: 2.6;non-classical monocyte: 4.3" "Lineage enriched" "Detected in single" 22 "monocytes: 4.3" "Cell line enriched" "Detected in single" 6 "EFO-21: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA071337 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Cytosol "HPA071337: " "unprognostic (4.47e-2)" "unprognostic (2.64e-3)" "unprognostic (5.18e-2)" "unprognostic (2.00e-2)" "unprognostic (7.47e-2)" "unprognostic (2.28e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (3.54e-1)" "unprognostic (2.13e-2)" "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-2)" "unprognostic (7.41e-2)" "unprognostic (5.50e-2)" "unprognostic (6.23e-2)" "unprognostic (4.07e-1)" 0.8 0.2 0.0 0.2 0.0 0.0 0.6 0.0 0.4 2.0 0.0 1.4 0.4 1.9 0.7 0.6 1.5 0.7 1.1 0.0 0.0 0.6 0.2 1.5 0.0 0.0 0.0 1.2 0.2 0.1 0.2 1.2 0.1 0.9 0.3 0.0 0.2 0.8 0.3 0.4 2.1 1.8 0.0 0.2 1.7 0.1 0.0 0.0 0.5 0.4 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.1 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.3 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.2 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 72.3 0.3 16.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 GPR37L1 ETBR-LP-2 ENSG00000170075 "G protein-coupled receptor 37 like 1" O60883 1 202122917-202133592 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 76.4" "Cell type enhanced" "Detected in some" "Astrocytes: 91.7;Muller glia cells: 59.6;Oligodendrocyte precursor cells: 89.0;Oligodendrocytes: 20.4" "Cancer enriched" "Detected in some" 57 "glioma: 36.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 1.2;MCF7: 1.5;T-47d: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061629, HPA064454" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 6: T47d - Mammary gland" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Cell Junctions" "Vesicles, Plasma membrane" "HPA061629: , HPA064454: AB_2685268" "unprognostic (2.12e-2)" "unprognostic (1.83e-1)" "unprognostic (2.96e-1)" "unprognostic (1.61e-3)" "unprognostic (4.52e-1)" "unprognostic (8.20e-2)" "unprognostic (2.26e-4)" "unprognostic (5.83e-2)" "unprognostic (3.46e-3)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "unprognostic (3.28e-2)" "unprognostic (4.86e-3)" "unprognostic (1.14e-1)" "unprognostic (4.58e-2)" "unprognostic (1.18e-3)" "unprognostic (3.49e-1)" 0.1 0.2 55.2 0.0 71.1 0.2 0.0 60.7 52.2 0.2 10.6 0.9 0.2 0.1 0.1 0.1 0.1 0.0 0.1 48.0 50.7 0.0 0.2 0.0 0.0 66.7 67.0 0.0 0.0 0.0 0.6 0.0 53.7 0.2 0.2 2.8 0.1 0.3 0.1 0.1 0.3 0.1 59.4 0.0 0.2 0.3 76.4 0.0 0.1 0.1 0.0 0.0 0.1 53.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 55.2 71.1 60.7 52.2 48.0 50.7 66.7 67.0 53.7 59.4 76.4 53.1 0.0 0.0 0.0 91.7 0.1 0.4 0.5 0.7 0.0 1.2 0.3 0.3 1.1 1.5 1.7 0.0 4.2 0.1 0.0 4.9 0.0 3.2 4.5 0.9 0.2 0.1 0.0 0.0 0.4 1.2 1.0 0.2 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.8 0.9 0.1 0.0 2.8 0.0 59.6 0.0 89.0 20.4 2.1 2.7 1.9 0.0 0.8 1.3 0.1 1.1 4.9 0.0 0.5 0.1 0.0 0.1 0.0 0.1 0.7 0.1 0.2 0.7 1.0 GPR50 "H9, Mel1c" ENSG00000102195 "G protein-coupled receptor 50" Q13585 X 151176584-151181465 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "pituitary gland: 17.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.4" "Region enhanced" "Detected in some" "hypothalamus: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEK 293: 5.0;SuSa: 4.0" "Group enriched" "Detected in many" 4 "hypothalamus: 14.4;white matter: 5.0" "Region enriched" "Detected in single" 10 "hypothalamus: 4.8" "HPA049862, HPA054678" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Plasma membrane" Nucleoplasm "HPA049862: AB_2680920, HPA054678: AB_2682570" "unprognostic (8.84e-3)" "unprognostic (5.59e-2)" "unprognostic (1.15e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 17.1 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 3.4 0.6 0.1 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPRIN1 "GRIN1, KIAA1893" ENSG00000169258 "G protein regulated inducer of neurite outgrowth 1" Q7Z2K8 5 176595802-176610156 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.1;pituitary gland: 8.1;retina: 6.9" "Group enriched" "Detected in some" 4 "Bipolar cells: 12.8;Excitatory neurons: 7.5;Horizontal cells: 21.9;Inhibitory neurons: 8.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 56.5;SCLC-21H: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036478, HPA070892" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" Vesicles "HPA036478: AB_2675145, HPA070892: AB_2686321" "unprognostic (1.70e-1)" "unprognostic (7.38e-2)" "unprognostic (4.41e-2)" "unprognostic (5.66e-2)" "unprognostic (6.54e-3)" "unprognostic (3.06e-1)" "unprognostic (4.76e-6)" "prognostic unfavorable (6.83e-6)" "unprognostic (1.11e-1)" "unprognostic (1.45e-1)" "unprognostic (2.59e-3)" "unprognostic (1.56e-3)" "prognostic unfavorable (2.79e-7)" "unprognostic (4.24e-3)" "unprognostic (5.60e-2)" "unprognostic (2.21e-1)" "unprognostic (3.32e-3)" 0.5 1.6 16.9 0.8 15.9 0.2 0.3 6.8 19.5 0.3 0.0 1.1 3.8 0.4 0.0 0.8 0.1 0.3 0.4 22.1 15.7 0.6 0.4 0.4 0.8 4.3 3.5 0.0 0.6 0.1 8.1 0.3 5.1 0.2 0.4 6.9 0.3 0.0 0.3 1.0 3.2 0.7 3.3 0.4 0.8 1.5 14.8 0.9 0.2 0.2 1.1 0.3 0.2 6.6 7.5 7.9 9.8 14.1 2.1 4.6 8.3 9.8 5.1 7.5 9.7 9.6 4.8 17.0 19.6 5.3 22.0 6.5 6.3 6.8 6.5 56.5 4.3 0.3 4.1 3.4 0.9 0.4 4.2 2.3 5.1 8.1 1.2 1.5 5.5 3.8 9.1 24.0 6.3 19.7 1.8 0.0 9.9 5.0 15.4 31.7 10.9 10.1 8.4 7.7 59.5 34.1 11.4 3.2 17.7 1.2 7.4 6.5 6.8 13.8 16.0 5.3 14.5 0.4 2.3 4.8 11.9 0.8 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 15.9 6.8 19.5 22.1 15.7 4.3 3.5 5.1 3.3 14.8 6.6 0.4 0.0 0.0 0.3 0.5 2.4 0.1 0.3 0.6 12.8 0.4 0.3 0.3 0.0 0.1 0.0 0.0 0.1 0.4 0.3 1.9 0.4 0.0 0.5 0.6 1.0 1.8 0.0 7.5 1.8 0.9 0.4 0.0 1.2 0.0 0.3 0.0 0.0 0.9 21.9 8.0 0.3 0.0 0.0 0.3 0.0 0.3 0.2 0.0 1.9 0.1 1.1 1.0 2.5 0.3 1.6 0.1 0.0 0.8 0.2 0.0 0.3 0.4 3.1 0.0 1.5 0.3 0.7 2.7 0.4 1.4 0.1 0.3 0.4 0.2 0.1 GRAMD1A "FLJ90346, KIAA1533" ENSG00000089351 "GRAM domain containing 1A" Q96CP6 19 34994784-35026471 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008852, HPA012570" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 50: Non-specific - Ribosome" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" Cytosol "HPA008852: AB_1079203, HPA012570: AB_2112577" "unprognostic (3.09e-2)" "unprognostic (4.62e-2)" "unprognostic (8.65e-2)" "unprognostic (1.01e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-1)" "unprognostic (3.42e-3)" "unprognostic (5.96e-2)" "unprognostic (4.54e-1)" "unprognostic (5.70e-2)" "unprognostic (1.07e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (7.95e-12)" "unprognostic (2.04e-1)" "unprognostic (4.40e-1)" "unprognostic (2.90e-2)" "unprognostic (4.36e-2)" 37.9 36.9 17.8 28.0 15.9 23.9 31.1 16.4 24.5 33.2 17.5 30.1 15.1 32.5 5.3 11.6 36.2 16.5 30.3 17.4 18.5 27.4 21.2 58.1 28.8 21.8 20.7 38.4 80.8 17.8 29.2 16.8 21.5 32.6 8.4 5.1 55.6 17.0 47.8 14.5 23.3 18.9 18.2 42.1 35.8 16.6 21.5 18.7 25.4 18.9 12.8 35.7 20.1 17.1 17.3 106.0 21.3 41.5 23.9 27.5 19.6 21.6 27.5 21.8 21.6 39.8 11.9 10.8 41.2 25.2 19.3 9.5 22.2 31.9 8.2 48.9 47.3 24.6 25.5 36.8 48.3 21.7 41.1 46.5 19.9 16.1 26.7 36.6 71.5 54.1 31.8 5.7 16.0 13.2 46.5 23.6 38.6 28.4 12.7 47.1 6.9 10.7 24.8 2.5 30.8 64.4 20.0 12.7 33.7 18.4 19.4 20.6 38.9 34.9 22.3 8.0 29.6 8.8 26.3 22.4 23.5 19.6 27.0 23.1 5.7 5.4 3.5 9.6 7.3 0.6 4.6 2.7 5.1 1.2 3.5 5.4 12.7 5.7 19.9 1.7 4.1 3.8 17.8 15.9 16.4 24.5 17.4 18.5 21.8 20.7 21.5 18.2 21.5 17.1 51.0 22.4 37.3 28.1 23.6 20.8 64.4 15.1 18.2 15.8 22.0 18.7 12.3 0.0 16.1 16.5 16.7 13.1 32.3 3.5 3.9 36.8 1.4 15.3 19.9 63.2 39.4 20.4 8.9 57.8 35.8 25.6 10.7 16.5 9.5 39.5 66.4 5.6 53.8 8.4 12.1 15.0 14.2 39.4 81.6 3.0 25.7 37.7 33.8 15.0 146.0 23.1 19.6 12.5 15.1 41.2 9.6 25.2 40.4 68.6 1.4 15.1 11.5 14.9 13.1 15.4 26.0 1.2 5.7 3.4 15.3 33.1 48.1 50.6 19.7 51.9 GRAMD1B "KIAA1201, LINC01059" ENSG00000023171 "GRAM domain containing 1B" Q3KR37 11 123358428-123627774 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 258.8;choroid plexus: 91.8;retina: 96.7" "Cell type enhanced" "Detected in many" "Astrocytes: 94.7;Cone photoreceptor cells: 114.7;Excitatory neurons: 120.7;Inhibitory neurons: 102.8;Oligodendrocyte precursor cells: 95.0;Rod photoreceptor cells: 92.3;Theca cells: 109.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 7.0" "Lineage enriched" "Detected in many" 4 "dendritic cells: 7.0" "Group enriched" "Detected in many" 4 "A549: 62.4;HDLM-2: 168.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008557, HPA075204" Approved Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum, Plasma membrane" Vesicles "HPA008557: AB_1079197, HPA075204: " "unprognostic (1.86e-1)" "unprognostic (7.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.74e-3)" "unprognostic (8.15e-2)" "unprognostic (4.28e-2)" "unprognostic (2.69e-3)" "unprognostic (4.12e-3)" "unprognostic (1.40e-1)" "unprognostic (2.90e-2)" "unprognostic (9.60e-2)" "unprognostic (8.06e-2)" "prognostic unfavorable (4.30e-7)" "unprognostic (1.39e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" 1.8 258.8 22.5 4.3 27.4 18.6 1.1 80.1 52.3 0.9 91.8 1.6 34.6 1.1 9.4 0.6 3.6 12.1 15.0 55.6 19.4 15.5 1.5 2.6 5.4 25.7 20.1 15.2 2.4 0.7 16.6 5.0 24.2 1.1 1.1 96.7 1.9 2.0 3.4 0.5 25.2 1.2 9.4 3.6 11.4 16.8 33.5 6.6 4.9 2.2 3.5 1.2 0.8 26.1 0.1 62.4 3.5 0.1 0.3 0.7 9.5 20.5 14.6 4.1 1.8 2.6 0.4 3.8 10.4 10.1 6.8 0.0 6.2 0.0 4.3 168.5 5.0 0.0 28.3 0.7 0.0 22.1 0.0 1.0 0.1 7.1 0.0 5.2 1.8 1.6 0.0 0.2 3.7 0.5 3.8 7.2 7.6 28.3 23.0 10.8 9.8 6.8 0.2 0.0 20.0 16.3 4.9 0.5 0.1 8.1 0.5 12.0 12.3 23.8 3.2 4.2 1.0 0.0 0.0 0.0 4.6 20.5 1.1 0.0 1.2 0.4 0.4 0.7 0.2 0.0 1.5 1.2 1.7 0.0 0.2 0.2 0.1 1.6 0.7 7.0 0.7 0.5 22.5 27.4 80.1 52.3 55.6 19.4 25.7 20.1 24.2 9.4 33.5 26.1 1.4 0.0 0.5 94.7 0.6 0.0 0.0 0.1 1.2 44.3 1.1 1.0 5.7 21.5 0.2 5.5 114.7 6.9 17.9 0.1 3.9 0.7 9.6 1.6 0.6 1.0 0.0 0.0 120.7 0.4 3.7 1.6 16.3 0.9 0.0 41.9 0.7 0.0 2.6 45.4 102.8 1.8 0.0 3.8 2.6 2.7 0.6 7.5 0.0 37.5 2.5 23.4 0.0 95.0 5.5 3.9 1.3 0.7 2.4 0.1 17.3 8.9 0.4 92.3 0.0 3.0 4.2 3.9 1.9 0.1 0.4 2.5 7.2 109.3 1.5 0.0 GRB7 ENSG00000141738 "Growth factor receptor bound protein 7" Q14451 17 39737927-39747291 "Cancer-related genes, Predicted intracellular proteins" "Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 60.2;kidney: 61.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 77.1;Basal squamous epithelial cells: 104.7;Prostatic glandular cells: 79.0;Squamous epithelial cells: 124.7;Syncytiotrophoblasts: 98.6;Urothelial cells: 79.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 11 "cerebellum: 5.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "OE19: 1706.0" "Region enhanced" "Detected in many" "cerebellum: 8.3" "Low region specificity" "Detected in many" "CAB005226, HPA057084, CAB073538" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "CAB005226: AB_2113278, CAB073538: , HPA057084: AB_2683330" "unprognostic (8.46e-2)" "unprognostic (2.06e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.60e-7)" "unprognostic (7.06e-3)" "unprognostic (2.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.85e-1)" "unprognostic (2.02e-1)" "prognostic unfavorable (3.10e-4)" "prognostic unfavorable (6.90e-4)" "unprognostic (2.59e-2)" "prognostic favorable (8.23e-5)" "unprognostic (1.83e-2)" "unprognostic (4.77e-2)" "unprognostic (5.49e-3)" "unprognostic (4.01e-2)" 5.9 0.1 0.0 0.7 0.4 0.0 14.2 5.6 0.4 13.5 4.5 8.1 11.8 3.3 3.8 60.2 22.3 9.5 1.2 0.2 0.0 61.5 11.1 10.6 0.1 0.0 0.4 1.0 32.7 11.4 6.9 11.9 0.5 14.5 10.0 0.1 25.2 11.6 0.3 39.9 10.8 1.0 0.0 0.5 16.9 1.2 0.1 1.1 6.6 0.1 8.7 7.5 26.2 0.3 12.6 14.4 0.0 0.0 0.0 0.0 19.1 0.0 0.8 0.1 0.5 44.7 24.3 0.0 4.2 0.4 0.9 24.1 0.0 16.1 0.0 0.0 2.1 0.0 6.4 38.5 0.0 0.0 0.0 0.0 15.1 0.2 3.7 2.5 0.1 0.0 0.0 0.0 0.0 11.5 0.2 0.1 4.9 1706.0 3.4 0.1 0.0 18.6 18.5 14.0 9.5 0.1 18.4 370.7 0.1 17.3 14.0 0.0 0.0 0.0 1.1 0.2 0.0 0.2 0.1 1.0 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.6 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.1 0.3 0.5 22.4 15.1 0.0 0.9 38.2 77.1 20.0 104.7 0.2 48.2 30.5 2.5 17.2 18.2 22.0 0.0 35.7 0.7 25.6 9.8 35.6 0.0 30.2 5.3 2.6 14.4 0.0 0.3 19.4 27.4 3.1 27.0 41.8 1.3 0.5 0.4 5.1 2.8 0.0 0.0 19.7 40.7 0.0 2.3 0.0 2.8 1.3 5.4 0.0 1.6 0.4 0.0 0.0 0.0 26.7 26.0 1.2 0.3 79.0 28.3 13.8 20.9 0.1 0.0 0.9 2.1 0.4 0.3 124.7 41.9 98.6 1.4 0.0 21.1 79.7 GRIK1 "GluK1, GLUR5" ENSG00000171189 "Glutamate ionotropic receptor kainate type subunit 1" P39086 21 29536933-29940033 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "adrenal gland: 12.5;brain: 32.6;retina: 38.2" "Group enriched" "Detected in some" 10 "Inhibitory neurons: 2260.1;Oligodendrocyte precursor cells: 862.5" "Cancer enriched" "Detected in some" 5 "glioma: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Daudi: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014623, HPA073879" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA014623: AB_1850305, HPA073879: " "unprognostic (1.39e-1)" "unprognostic (6.54e-2)" "unprognostic (1.32e-1)" "unprognostic (1.04e-2)" "unprognostic (1.03e-3)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.12e-3)" "unprognostic (1.25e-1)" "unprognostic (8.77e-2)" "unprognostic (4.89e-3)" "unprognostic (1.20e-3)" "unprognostic (1.47e-8)" "unprognostic (2.09e-1)" "unprognostic (2.68e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-3)" 0.2 12.5 7.5 0.2 6.6 0.1 1.8 2.4 6.0 0.8 0.0 0.3 0.0 0.1 2.0 0.3 0.0 0.1 0.0 8.4 12.3 0.0 0.1 0.1 0.1 30.0 11.2 0.3 0.0 0.0 0.2 0.4 32.6 2.4 0.5 38.2 0.0 0.1 0.1 0.8 0.4 0.1 2.6 0.1 0.2 0.5 9.7 0.0 0.0 0.0 0.0 0.4 0.4 2.9 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.5 6.6 2.4 6.0 8.4 12.3 30.0 11.2 32.6 2.6 9.7 2.9 0.1 0.0 0.0 27.4 0.0 0.3 0.0 0.0 0.0 149.8 2.3 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.8 0.1 1.2 0.4 0.0 0.0 29.8 0.0 0.0 0.7 0.0 0.2 0.0 148.8 0.0 0.0 0.1 1.7 2260.1 0.0 0.0 0.0 0.4 13.2 0.3 0.2 3.6 10.3 0.0 2.5 0.0 862.5 8.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.9 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 0.1 33.8 0.1 0.0 GRIK5 "GluK5, GRIK2, KA2" ENSG00000105737 "Glutamate ionotropic receptor kainate type subunit 5" Q16478 19 41998321-42069498 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.5;testis: 32.9" "Cell type enhanced" "Detected in some" "Astrocytes: 17.9;Bipolar cells: 23.0;Excitatory neurons: 32.4;Horizontal cells: 18.5;Inhibitory neurons: 31.1;Oligodendrocyte precursor cells: 31.7;Rod photoreceptor cells: 21.2" "Group enriched" "Detected in many" 5 "glioma: 15.4;ovarian cancer: 6.6;thyroid cancer: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 13.7;hTERT-RPE1: 21.2;NTERA-2: 13.1;REH: 37.5;SCLC-21H: 10.3;SH-SY5Y: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074001 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 14: REH - Unknown function" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" Nucleoplasm "HPA074001: AB_2732248" "unprognostic (4.99e-2)" "unprognostic (3.40e-1)" "unprognostic (1.30e-3)" "unprognostic (6.68e-3)" "unprognostic (4.28e-2)" "unprognostic (3.86e-1)" "unprognostic (5.82e-1)" "unprognostic (2.23e-1)" "unprognostic (3.89e-2)" "unprognostic (1.73e-2)" "prognostic favorable (7.23e-4)" "unprognostic (8.43e-2)" "prognostic unfavorable (9.32e-4)" "unprognostic (6.47e-3)" "unprognostic (5.77e-2)" "unprognostic (4.57e-2)" "unprognostic (6.12e-2)" 1.6 4.0 20.0 1.7 17.3 3.0 1.2 6.2 26.7 5.3 0.1 16.4 0.7 7.3 1.8 1.6 6.8 1.9 4.9 36.5 15.5 7.0 0.3 0.5 0.7 3.6 4.8 3.6 2.7 14.8 18.3 0.0 7.0 6.2 1.0 12.5 0.7 6.5 0.5 0.9 3.4 5.2 3.0 1.3 5.3 32.9 14.6 0.9 11.3 0.7 0.6 5.0 2.7 6.6 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.4 0.3 13.7 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.1 0.0 21.2 0.0 0.6 0.1 0.6 0.0 0.2 0.2 0.0 13.1 0.1 0.0 37.5 0.0 0.1 5.8 0.1 10.3 22.7 0.1 0.0 0.2 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 1.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 17.3 6.2 26.7 36.5 15.5 3.6 4.8 7.0 3.0 14.6 6.6 0.2 0.0 0.0 17.9 0.1 0.4 0.1 0.0 0.0 23.0 0.2 0.8 3.1 0.0 0.0 1.8 2.1 0.0 0.0 0.1 0.0 0.8 1.6 0.2 0.2 0.4 0.0 0.0 32.4 0.0 0.0 0.6 0.0 0.3 4.5 7.2 0.0 0.0 0.0 18.5 31.1 0.0 0.0 0.0 0.0 2.3 0.9 0.1 0.0 2.8 0.0 9.1 0.0 31.7 0.9 0.1 0.0 0.4 0.0 0.4 0.0 0.0 0.0 21.2 0.0 4.9 1.7 4.2 2.2 0.2 0.4 0.0 0.0 0.0 0.0 0.1 GRK5 GPRK5 ENSG00000198873 "G protein-coupled receptor kinase 5" P34947 10 119207571-119459745 "Enzymes, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Microglial cells: 56.2;Sertoli cells: 59.2;Smooth muscle cells: 46.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.1;HUVEC TERT2: 24.9;OE19: 25.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025579, HPA046838" Approved Supported "Nuclear membrane,Nuclear speckles,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "Nuclear membrane, Nuclear speckles" "Plasma membrane" "CAB025579: , HPA046838: AB_2679833" "unprognostic (1.09e-1)" "unprognostic (3.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.02e-2)" "unprognostic (6.56e-2)" "unprognostic (3.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.69e-1)" "unprognostic (4.11e-1)" "unprognostic (1.06e-1)" "unprognostic (3.70e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.10e-1)" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" 38.4 18.0 4.2 5.9 5.0 2.7 24.6 5.0 4.6 18.8 3.5 26.3 10.0 21.1 3.5 12.6 19.6 5.7 48.8 4.0 5.1 14.2 12.9 65.6 7.8 3.9 3.6 35.0 4.7 21.3 13.3 8.3 3.9 14.1 4.9 1.0 7.8 4.0 11.9 11.5 25.8 7.3 3.3 37.0 27.5 4.1 4.9 6.2 19.6 9.7 6.8 19.4 18.1 3.5 3.7 2.3 5.4 5.7 11.8 11.0 1.6 7.1 32.1 4.1 2.3 1.7 5.4 3.9 1.6 11.1 7.5 0.9 2.3 7.7 2.7 15.4 2.0 0.7 4.6 7.0 8.2 0.2 2.0 1.5 1.1 8.5 1.2 5.2 24.9 2.4 0.4 3.7 1.5 0.7 3.8 3.5 0.8 25.8 5.2 1.3 0.8 0.9 0.6 1.5 1.8 4.9 2.4 1.1 7.0 3.0 0.1 0.9 7.8 2.3 1.6 14.6 2.8 0.9 4.4 2.4 4.9 4.4 2.4 0.4 1.5 2.9 2.0 1.4 0.1 3.8 3.0 1.6 0.9 4.0 4.5 2.0 2.1 0.1 0.5 0.0 4.0 1.7 4.2 5.0 5.0 4.6 4.0 5.1 3.9 3.6 3.9 3.3 4.9 3.5 32.6 57.7 3.7 3.6 19.7 1.7 0.7 0.5 1.2 3.9 2.3 2.0 19.4 0.0 1.3 3.7 0.0 3.7 13.3 0.4 0.0 1.1 18.7 0.4 5.1 28.4 4.8 0.0 17.7 3.1 15.8 35.7 18.8 1.0 4.5 7.8 24.7 2.2 4.4 1.7 36.5 0.8 6.1 15.5 6.3 4.9 4.4 14.2 7.2 56.2 3.6 0.0 19.6 14.1 5.7 2.4 1.2 4.5 10.2 0.7 4.9 0.6 0.8 0.9 59.2 18.2 46.5 1.3 2.1 0.7 2.4 13.1 14.1 4.6 0.5 0.9 GRPR "BB2, BB2R" ENSG00000126010 "Gastrin releasing peptide receptor" P30550 X 16123565-16153518 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "pancreas: 20.3" "Cell type enriched" "Detected in single" 15 "Inhibitory neurons: 6.3" "Cancer enriched" "Detected in some" 4 "breast cancer: 6.6" "Region enhanced" "Detected in some" "hypothalamus: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "PC-3: 29.2;T-47d: 38.2;U-138 MG: 51.5" "Region enhanced" "Detected in single" "hypothalamus: 2.0" "Low region specificity" "Detected in all" HPA069604 Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA069604: AB_2686158" "unprognostic (3.32e-2)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (2.87e-1)" "unprognostic (9.17e-2)" "unprognostic (5.06e-2)" "unprognostic (2.82e-1)" "unprognostic (1.01e-1)" "unprognostic (3.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.57e-1)" "unprognostic (5.59e-2)" "unprognostic (2.15e-2)" "unprognostic (2.56e-1)" "unprognostic (2.92e-1)" "unprognostic (2.86e-2)" 0.1 0.1 0.1 0.2 0.2 0.1 1.9 0.0 0.3 0.3 0.1 0.4 0.1 0.5 1.9 0.0 0.1 0.1 0.2 0.2 1.6 0.0 0.0 0.1 0.1 0.3 0.0 0.0 20.3 0.2 0.0 0.1 0.2 0.5 0.3 0.1 0.0 0.1 0.2 0.0 0.1 0.8 1.1 0.1 1.1 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.3 0.0 0.9 0.1 4.0 1.6 0.4 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.2 0.5 0.0 0.0 0.0 0.5 0.0 29.2 0.0 0.1 0.1 0.1 0.0 0.8 0.1 0.0 0.1 0.1 1.5 38.2 0.1 0.2 51.5 1.9 0.0 1.6 0.3 0.2 0.2 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.2 1.6 0.3 0.0 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GSDMA "FLJ39120, GSDM, GSDM1" ENSG00000167914 "Gasdermin A" Q96QA5 17 39953263-39977768 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 58.9" "Group enriched" "Detected in some" 5 "Collecting duct cells: 3.7;Hofbauer cells: 5.0;Kupffer cells: 5.6;Macrophages: 2.6;Suprabasal keratinocytes: 2.7;Theca cells: 2.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.6" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HBEC3-KT: 4.1;hTCEpi: 2.7;hTERT-HME1: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023313, HPA064826" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 44000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA023313: AB_1850378, HPA064826: AB_2685361" "unprognostic (1.32e-2)" "unprognostic (2.01e-1)" "unprognostic (2.95e-2)" "unprognostic (1.06e-1)" "unprognostic (3.62e-1)" "unprognostic (1.97e-1)" "unprognostic (7.77e-2)" "unprognostic (1.39e-1)" "unprognostic (3.24e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" "unprognostic (2.90e-2)" "unprognostic (1.06e-2)" "unprognostic (9.86e-2)" "unprognostic (7.45e-2)" "unprognostic (3.63e-2)" "unprognostic (3.79e-2)" 3.4 0.7 0.2 0.9 0.2 0.4 3.5 0.4 0.4 0.8 0.2 0.7 0.6 0.4 6.6 3.2 0.3 0.8 0.3 0.3 0.2 0.3 0.3 0.4 0.7 0.4 0.0 0.1 0.3 1.3 0.1 1.6 0.4 0.1 1.2 0.0 0.8 0.0 0.4 58.9 0.5 0.6 0.0 0.2 0.3 0.3 0.4 0.5 0.1 0.1 3.4 1.1 1.5 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.5 0.4 0.2 0.0 0.1 0.8 0.0 2.7 0.5 5.4 0.0 0.0 0.0 0.1 1.3 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.9 0.1 0.1 2.2 0.0 2.6 0.0 1.3 0.8 0.1 0.1 0.6 0.9 0.7 0.1 0.1 0.2 0.5 0.5 0.2 0.2 0.4 0.4 0.3 0.2 0.4 0.0 0.4 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 3.7 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.7 0.0 5.0 0.0 0.1 0.7 0.0 5.6 0.6 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.7 0.0 0.2 2.8 0.0 0.0 GYPA "CD235a, GPA, MN, MNS" ENSG00000170180 "Glycophorin A (MNS blood group)" P02724 4 144109303-144140751 "Blood group antigen proteins, CD markers, Predicted membrane proteins" "Host-virus interaction" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "bone marrow: 156.3" "Cell type enriched" "Detected in some" 350 "Erythroid cells: 1995.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebral cortex: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 203 "HEL: 149.1;K-562: 37.7" "CAB002658, HPA014811" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 15000000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Plasma membrane, Cytosol" "CAB002658: , HPA014811: AB_1849827" "unprognostic (1.60e-1)" "unprognostic (2.47e-2)" 0.1 0.1 0.1 0.0 0.1 156.3 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 2.3 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 4.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 149.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.9 0.0 0.7 0.0 0.0 0.0 0.0 1995.6 2.4 0.0 2.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 1.7 0.0 0.0 0.9 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.6 0.2 0.0 0.0 GYPC "CD236, CD236R, Ge, GPC, GYPD" ENSG00000136732 "Glycophorin C (Gerbich blood group)" P04921 2 126656133-126696667 "Blood group antigen proteins, CD markers, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 441.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 1728.6;Hofbauer cells: 488.7" "Cancer enhanced" "Detected in all" "melanoma: 66.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 433.1;K-562: 362.1;SK-MEL-30: 668.4;U-266/70: 363.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008965, CAB009445" Enhanced Supported "Plasma membrane" NA NA 970000 "Cluster 20: T-cells - T-cell receptor" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "CAB009445: AB_2116251, HPA008965: AB_1078455" "unprognostic (1.63e-2)" "unprognostic (7.14e-3)" "unprognostic (8.39e-2)" "unprognostic (3.31e-3)" "unprognostic (4.19e-2)" "unprognostic (1.69e-2)" "unprognostic (8.82e-2)" "unprognostic (3.52e-1)" "unprognostic (1.19e-1)" "unprognostic (2.21e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.05e-2)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (2.29e-1)" "unprognostic (8.00e-3)" 172.3 73.0 17.3 51.5 17.6 441.0 109.2 17.5 30.8 75.7 20.2 89.1 18.2 62.3 20.2 42.3 68.4 56.3 161.9 16.5 20.2 58.4 18.5 101.4 110.5 22.2 18.4 91.5 34.8 9.6 16.9 50.3 22.0 46.5 19.3 10.3 26.4 56.1 212.7 37.0 52.9 55.9 20.6 98.5 41.0 7.3 23.6 59.6 33.3 204.1 75.9 73.0 54.4 24.9 1.3 0.0 152.0 0.2 116.1 100.5 0.2 24.0 186.4 28.9 84.9 0.0 0.2 0.6 0.4 69.6 107.6 0.3 85.7 0.1 9.5 79.7 0.0 279.0 0.0 0.0 433.1 99.0 0.7 237.4 0.0 23.1 0.1 2.3 1.0 190.4 362.1 214.6 70.5 0.0 0.1 148.9 46.7 0.0 0.4 18.1 12.1 0.4 11.8 0.0 0.2 0.0 0.3 0.0 668.4 20.7 0.0 258.5 65.7 107.3 1.0 7.3 1.2 363.9 257.4 0.5 51.4 135.8 99.3 0.8 28.6 2.2 153.1 40.3 172.2 95.8 136.7 186.5 50.0 102.6 190.5 188.3 21.9 81.1 24.7 27.1 179.4 119.0 17.3 17.6 17.5 30.8 16.5 20.2 22.2 18.4 22.0 20.6 23.6 24.9 260.7 6.4 7.7 0.7 152.7 38.0 3.4 17.0 43.3 0.6 14.6 110.5 34.9 84.4 6.0 14.7 2.1 4.9 194.0 0.0 135.0 202.9 1.6 3.6 99.8 157.2 0.0 1728.6 0.4 4.9 6.9 170.5 10.2 2.5 22.9 23.3 229.2 6.2 488.7 0.0 0.5 1.1 0.0 118.0 108.5 4.9 87.3 134.9 305.9 15.0 98.0 5.1 204.9 6.0 0.1 6.0 0.4 69.2 250.9 9.4 0.0 8.1 1.7 2.6 59.2 65.8 88.6 0.2 0.7 41.9 26.6 9.0 228.0 31.8 1.6 2.9 HAS1 HAS ENSG00000105509 "Hyaluronan synthase 1" Q92839 19 51713112-51723991 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 49.6;ovary: 20.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 26.6;Bipolar cells: 20.3;Cholangiocytes: 38.6;Fibroblasts: 64.2;Suprabasal keratinocytes: 17.8" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "eosinophil: 2.5" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.5" "Cell line enriched" "Detected in some" 4 "U-87 MG: 112.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA067602 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA067602: AB_2685871" "unprognostic (3.56e-2)" "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "unprognostic (5.26e-4)" "unprognostic (7.17e-3)" "unprognostic (7.05e-2)" "unprognostic (1.02e-1)" "unprognostic (5.49e-4)" "unprognostic (4.80e-2)" "unprognostic (1.99e-2)" "unprognostic (8.43e-2)" "unprognostic (1.72e-1)" "unprognostic (2.30e-11)" "unprognostic (9.12e-4)" "unprognostic (8.99e-2)" "unprognostic (3.73e-4)" "unprognostic (2.43e-2)" 49.6 0.5 1.4 6.3 1.1 3.6 1.3 1.1 1.1 0.1 0.0 2.8 0.1 1.0 0.0 0.8 9.0 5.5 9.2 0.9 2.0 0.5 0.6 3.7 0.0 1.8 0.8 20.8 2.1 0.3 0.9 0.3 0.7 0.2 0.5 0.2 0.2 0.0 0.2 5.4 1.3 0.7 0.3 0.3 1.7 0.3 2.2 0.1 0.7 0.0 0.0 6.3 0.6 1.3 0.0 0.5 0.0 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.1 3.2 0.0 27.0 0.0 0.1 0.0 0.0 0.0 0.2 6.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.0 0.3 0.8 0.0 0.0 0.0 0.0 112.6 0.0 0.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 1.1 1.1 1.1 0.9 2.0 1.8 0.8 0.7 0.3 2.2 1.3 1.5 0.0 1.8 0.0 0.2 26.6 0.1 0.8 0.6 20.3 0.0 0.0 1.3 38.6 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.5 0.5 0.0 0.0 1.7 0.0 0.2 64.2 2.6 0.0 2.5 0.0 0.0 0.1 0.2 0.0 1.5 0.0 0.0 0.8 9.0 0.2 0.3 8.3 8.8 0.0 0.0 0.2 0.0 0.0 0.9 0.1 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.5 0.0 3.1 10.6 0.1 0.5 0.4 17.8 0.1 0.3 0.0 0.0 0.2 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 150.7;Kupffer cells: 155.5;Langerhans cells: 89.2;Macrophages: 170.1;Microglial cells: 52.5;monocytes: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 9 "THP-1: 69.3;U-937: 199.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 24.8 9.2 4.7 100.0 5.0 55.2 6.0 5.5 6.0 5.5 13.7 12.8 15.2 3.1 2.6 6.7 7.6 14.4 4.8 4.7 6.2 4.7 14.1 46.0 38.6 9.9 6.8 2.5 4.5 2.1 3.1 20.9 8.3 4.0 13.6 0.5 5.1 4.7 1.6 5.8 17.8 25.3 8.1 112.1 6.7 2.3 8.4 14.5 2.8 6.9 39.3 32.8 4.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.1 0.1 1.3 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 15.6 0.0 0.1 0.1 4.9 0.4 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.7 0.0 69.3 0.0 0.0 0.3 0.0 0.1 1.9 0.3 10.3 0.0 199.6 0.0 6.4 575.0 707.8 1.1 1059.1 1.3 48.4 1.1 1.1 336.3 43.0 1.1 0.9 801.3 11.0 1251.7 30.4 1.2 566.4 4.7 5.0 5.5 6.0 4.7 6.2 9.9 6.8 8.3 8.1 8.4 12.0 0.6 6.4 14.0 0.0 17.1 3.1 4.0 0.2 0.6 0.1 0.4 1.3 2.0 1.5 3.9 7.3 0.0 0.9 12.1 0.2 1.9 0.1 2.5 0.1 0.1 3.7 1.8 1.7 1.2 0.6 0.9 1.3 4.6 0.1 6.3 0.1 1.1 2.3 150.7 0.0 1.0 0.5 22.4 155.5 89.2 0.3 0.0 170.1 1.8 52.5 222.0 0.0 4.1 1.5 0.6 0.0 0.0 0.0 0.7 0.5 0.1 0.3 1.5 0.1 0.0 0.6 0.5 0.2 0.3 0.2 1.1 1.6 3.0 0.2 0.9 3.7 HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 153.6;lymphoid tissue: 300.3" "Cell type enhanced" "Detected in many" "B-cells: 175.7;Kupffer cells: 666.3;Macrophages: 269.0;monocytes: 245.7;NK-cells: 216.3;T-cells: 181.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 265.6;HMC-1: 362.3;RPMI-8226: 256.5;THP-1: 262.8;U-266/70: 361.6;U-698: 371.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 870000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA019143: AB_1850532" "unprognostic (2.27e-2)" "unprognostic (1.79e-3)" "unprognostic (5.38e-3)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-3)" "unprognostic (2.35e-1)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "unprognostic (6.76e-2)" "unprognostic (2.28e-1)" "unprognostic (1.03e-3)" "unprognostic (2.93e-1)" "unprognostic (3.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" 67.0 32.9 14.6 147.2 14.7 153.6 25.5 15.4 18.7 20.7 15.8 29.2 21.2 13.7 6.4 15.7 21.5 37.8 18.4 14.3 17.0 21.5 39.1 52.7 207.6 21.6 17.5 9.4 11.9 7.7 14.6 51.4 20.8 15.8 31.4 2.3 16.0 11.1 7.3 11.1 68.7 34.6 18.5 300.3 27.1 4.5 18.2 140.3 15.4 18.8 242.8 53.0 13.7 23.0 0.8 0.0 0.2 0.1 20.9 11.5 5.7 4.1 4.0 0.8 1.6 0.1 0.0 265.6 124.6 0.0 0.2 0.3 6.9 9.9 1.1 120.6 0.0 172.6 0.0 0.0 11.6 192.4 362.3 2.2 0.5 0.0 1.5 0.0 153.4 106.2 35.1 235.9 0.0 0.0 137.9 162.9 0.3 0.2 4.5 137.1 0.2 256.5 0.0 68.0 0.3 0.2 0.2 0.4 0.6 0.6 0.1 262.8 203.5 0.0 2.0 0.3 0.9 361.6 118.1 371.5 1.9 181.5 0.2 357.3 713.1 1180.9 405.3 870.4 333.0 345.7 334.2 376.8 636.2 313.1 279.3 326.2 1619.2 280.0 997.1 197.4 494.2 1427.9 14.6 14.7 15.4 18.7 14.3 17.0 21.6 17.5 20.8 18.5 18.2 23.0 23.0 9.6 31.8 1.0 175.7 3.2 1.0 7.8 0.6 0.5 2.7 5.1 2.3 4.3 13.1 0.0 0.0 122.4 139.5 0.8 0.0 0.3 1.1 8.8 1.6 23.3 0.0 50.5 1.4 0.2 60.0 7.0 8.6 3.1 73.4 0.7 27.8 7.7 126.9 0.0 0.7 0.4 4.1 666.3 105.8 1.5 3.4 269.0 19.6 26.2 245.7 0.4 216.3 0.5 0.3 0.2 0.2 1.2 148.6 0.4 0.1 0.9 24.7 0.8 13.1 3.7 6.7 0.6 0.6 1.3 4.4 145.4 181.4 2.4 0.5 2.2 HCST "DAP10, DKFZP586C1522, KAP10, PIK3AP" ENSG00000126264 "Hematopoietic cell signal transducer" Q9UBK5 19 35902529-35904377 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 253.7;lymphoid tissue: 115.6" "Cell type enhanced" "Detected in many" "dendritic cells: 993.2;Hofbauer cells: 571.1;Kupffer cells: 396.6;Langerhans cells: 584.5;Macrophages: 392.7;NK-cells: 1687.0;T-cells: 769.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 239.9;HL-60: 139.6;HMC-1: 154.3;THP-1: 177.8;U-937: 272.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB034435, HPA063026" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Plasma membrane" Vesicles "CAB034435: AB_2117803, HPA063026: " "unprognostic (1.40e-3)" "unprognostic (3.07e-2)" "unprognostic (3.04e-2)" "unprognostic (7.27e-3)" "unprognostic (1.23e-1)" "unprognostic (8.23e-3)" "unprognostic (1.85e-1)" "unprognostic (2.54e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.97e-2)" "unprognostic (1.94e-3)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.59e-10)" "unprognostic (3.78e-1)" "unprognostic (3.25e-2)" "unprognostic (1.65e-1)" "unprognostic (1.56e-1)" 27.2 9.5 14.0 53.6 13.8 253.7 14.1 13.7 18.5 9.6 16.6 12.7 11.3 8.3 4.7 5.5 9.9 11.5 8.3 13.5 17.0 10.6 14.5 40.3 68.0 18.3 14.7 5.7 6.7 2.5 9.6 24.7 17.6 9.4 8.6 2.2 10.7 8.2 4.2 6.6 28.2 11.2 17.1 115.6 15.4 3.4 18.2 59.6 7.9 3.0 37.8 16.4 8.0 22.2 0.9 0.0 0.3 0.5 1.1 0.0 0.3 1.9 1.1 0.0 0.6 0.8 1.2 26.9 1.7 2.0 0.4 0.9 0.0 0.2 0.0 0.6 0.0 239.9 0.5 0.7 0.9 139.6 154.3 1.6 0.3 0.0 0.0 0.7 0.0 14.8 2.1 33.4 0.4 0.4 16.9 54.7 0.3 0.3 0.7 0.8 0.5 2.0 0.4 0.1 0.9 0.4 1.3 0.7 0.9 0.2 0.5 177.8 0.5 1.4 1.8 0.2 0.2 1.6 1.1 39.5 1.4 272.2 0.3 124.7 725.8 105.8 1583.4 546.1 1172.3 78.6 664.6 1293.3 409.8 51.0 550.6 1108.0 196.1 1290.7 314.4 823.7 629.9 1421.2 14.0 13.8 13.7 18.5 13.5 17.0 18.3 14.7 17.6 17.1 18.2 22.2 12.3 6.4 43.3 0.0 85.3 28.6 1.3 1.7 2.8 0.4 11.4 12.8 1.2 15.7 7.1 9.2 0.0 3.8 993.2 1.8 0.0 2.8 1.3 4.0 2.5 18.3 0.0 84.2 0.1 1.2 4.7 9.5 14.8 5.5 240.4 0.3 21.0 14.3 571.1 1.7 0.1 0.9 2.0 396.6 584.5 3.0 2.1 392.7 44.4 5.6 309.9 0.7 1687.0 0.0 0.1 1.0 1.4 0.0 97.7 0.6 2.0 6.1 5.1 2.2 19.7 4.2 6.2 2.2 4.9 2.7 21.0 6.0 769.9 1.0 2.7 1.2 HFE "HFE1, HLA-H" ENSG00000010704 "Homeostatic iron regulator" Q30201 6 26087281-26098343 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Kupffer cells: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 39.2;T-47d: 54.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017276, HPA053470" Approved Supported "Nucleoplasm,Plasma membrane" No No "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Nucleoplasm "HPA017276: AB_1850677, HPA053470: AB_2682163" "unprognostic (6.96e-2)" "unprognostic (7.87e-2)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (6.07e-3)" "unprognostic (7.58e-2)" "unprognostic (4.23e-1)" "unprognostic (1.77e-1)" "unprognostic (8.21e-3)" "unprognostic (1.78e-1)" "unprognostic (3.31e-3)" "unprognostic (1.82e-1)" "unprognostic (1.33e-2)" "unprognostic (2.12e-2)" "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (3.17e-1)" 9.6 7.9 1.3 5.3 2.1 0.6 7.8 1.4 1.9 6.7 9.3 5.8 5.9 4.9 12.4 4.8 4.5 8.1 3.7 1.5 1.5 6.7 15.4 7.5 3.6 2.4 1.7 7.3 6.3 15.4 1.2 6.1 2.2 6.8 6.9 1.3 6.9 9.6 2.3 2.8 5.0 6.0 1.7 8.6 8.3 1.7 1.9 1.7 9.9 3.0 3.1 7.4 3.2 2.8 17.2 39.2 0.7 18.6 27.3 21.1 0.1 12.2 28.5 15.1 23.6 3.3 34.3 1.8 32.4 20.2 22.9 10.7 0.0 14.2 19.1 4.6 0.2 0.5 8.1 2.6 5.6 0.0 0.7 21.6 4.0 16.7 1.4 13.2 10.4 0.0 0.7 0.4 13.0 7.2 0.1 0.2 0.9 8.1 0.0 2.3 0.0 0.3 12.5 11.5 0.1 0.1 7.3 0.0 10.2 0.3 54.0 1.9 8.2 10.6 1.1 10.7 10.6 0.2 0.4 0.2 15.9 0.2 23.5 1.3 10.7 0.0 1.5 10.4 1.2 3.3 1.6 2.1 4.7 1.3 0.4 1.0 1.9 0.2 9.2 0.3 0.3 3.8 1.3 2.1 1.4 1.9 1.5 1.5 2.4 1.7 2.2 1.7 1.9 2.8 3.9 3.2 5.1 1.0 1.7 1.7 2.6 3.7 6.2 1.0 3.7 2.2 3.2 2.8 6.7 5.5 2.1 1.7 0.5 3.8 0.0 4.1 0.1 1.8 2.3 3.4 1.8 2.7 0.1 3.4 0.8 4.6 8.2 1.5 2.5 3.0 6.8 12.2 11.1 0.0 0.1 4.0 4.1 25.4 7.6 0.2 3.7 7.4 0.0 2.8 3.8 2.9 2.1 0.0 3.3 2.4 0.9 6.0 0.3 2.6 2.9 2.7 5.9 1.7 0.0 5.7 2.4 0.2 1.1 3.4 3.4 1.8 1.0 2.8 3.3 1.9 HINT1 "HINT, PKCI-1, PRKCNH1" ENSG00000169567 "Histidine triad nucleotide binding protein 1" P49773 5 131155383-131224468 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 3537.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044577 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 2800000 "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Cytosol "Nucleoplasm, Plasma membrane" "HPA044577: AB_10795618" "unprognostic (2.00e-1)" "unprognostic (9.27e-2)" "unprognostic (2.04e-2)" "unprognostic (1.03e-2)" "unprognostic (1.19e-1)" "unprognostic (1.35e-1)" "unprognostic (8.30e-3)" "unprognostic (2.48e-1)" "unprognostic (1.30e-2)" "unprognostic (6.49e-2)" "unprognostic (6.50e-3)" "unprognostic (4.43e-2)" "unprognostic (4.39e-3)" "unprognostic (2.08e-1)" "unprognostic (1.74e-1)" "unprognostic (1.67e-1)" "unprognostic (3.68e-1)" 132.6 175.0 235.7 139.8 245.1 259.3 172.7 241.6 326.2 117.6 243.8 227.6 176.1 119.6 187.5 181.3 165.6 108.0 167.2 245.9 247.8 256.7 474.2 119.0 206.5 241.6 237.2 121.5 165.5 285.6 152.5 87.5 249.1 155.1 226.5 110.8 172.8 116.4 334.1 170.0 196.3 124.2 242.6 126.9 136.5 80.1 240.8 166.5 177.2 278.4 192.3 152.9 129.7 245.3 437.1 522.7 448.2 877.2 273.1 297.1 441.3 300.3 230.9 235.4 272.1 547.1 516.8 563.3 625.7 329.6 569.1 253.4 315.4 635.3 244.1 500.0 514.6 199.1 814.0 771.9 532.6 349.4 65.4 400.1 618.6 295.8 528.2 533.7 314.1 727.8 313.4 1132.1 338.8 419.9 548.0 945.6 415.6 425.6 362.0 407.9 436.1 988.1 500.6 567.0 563.3 351.9 380.5 243.5 612.0 574.4 291.2 520.8 396.0 351.7 244.0 323.0 684.2 342.3 561.4 578.8 497.8 586.8 346.3 179.8 187.9 85.0 196.3 109.9 298.0 384.9 462.0 294.2 396.9 332.6 416.0 325.5 35.6 269.0 128.0 521.4 362.5 608.6 235.7 245.1 241.6 326.2 245.9 247.8 241.6 237.2 249.1 242.6 240.8 245.3 582.7 282.0 279.1 34.3 718.2 1301.2 1472.2 1928.1 889.5 191.2 1134.3 1831.1 517.0 1028.0 882.2 715.4 45.9 780.9 641.6 1245.1 1663.0 1024.5 783.0 718.9 443.7 501.2 698.1 669.7 53.8 774.3 1632.8 400.2 355.2 753.7 108.2 666.5 436.2 2380.1 887.1 148.0 48.0 947.2 915.5 472.4 906.9 206.3 392.4 447.0 965.8 34.7 1269.4 405.1 488.1 26.7 55.4 894.3 1094.2 418.6 679.7 1998.9 1690.3 3537.5 708.3 194.0 243.3 287.0 730.3 625.5 197.9 1109.1 1146.1 456.8 671.1 464.3 1280.4 1713.2 HLA-A ENSG00000206503 "Major histocompatibility complex, class I, A" P04439 6 29941260-29945884 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 3747.8;Proximal enterocytes: 5267.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 1363.9;fHDF/TERT166: 360.3;HBEC3-KT: 366.7;RPMI-8226: 372.1;U-266/70: 344.6" CAB078470 Supported "Golgi apparatus,Plasma membrane" NA NA 170000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Golgi apparatus" "CAB078470: AB_10985125" "unprognostic (1.56e-2)" "unprognostic (9.14e-2)" "unprognostic (1.34e-2)" "prognostic favorable (9.59e-4)" "unprognostic (3.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "unprognostic (7.28e-2)" "unprognostic (3.42e-2)" "prognostic favorable (6.47e-4)" "unprognostic (2.96e-1)" "unprognostic (3.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (1.54e-2)" 635.4 714.2 15.0 34.8 15.5 137.7 566.7 14.7 36.5 504.9 18.0 737.5 278.3 476.1 181.1 366.8 390.3 239.9 473.4 14.6 17.0 687.0 392.0 1007.3 132.0 19.1 15.8 338.8 200.0 18.5 406.5 52.1 16.5 370.9 94.6 9.9 364.1 1.2 246.5 673.3 959.1 14.5 16.8 1413.1 442.2 132.6 18.0 138.9 531.9 14.5 178.3 412.3 466.8 18.3 1363.9 35.0 0.0 0.0 205.9 193.7 1.4 1.4 2.5 2.1 2.3 0.2 0.1 4.0 0.6 360.3 179.1 31.2 0.2 366.7 0.5 3.1 13.5 237.5 9.5 7.4 11.2 0.5 14.4 2.0 0.0 2.5 1.1 0.6 0.2 177.8 0.4 1.4 0.5 0.0 1.1 24.3 2.9 0.2 4.1 27.5 2.5 372.1 246.7 276.5 0.6 12.4 29.3 0.2 11.8 82.8 1.6 30.4 5.8 18.7 0.8 5.8 4.0 344.6 92.6 77.7 0.4 199.9 0.2 321.6 119.0 182.7 164.7 95.5 134.8 96.9 125.4 146.3 18.6 64.3 86.5 119.2 248.7 133.1 109.6 54.6 222.2 191.9 15.0 15.5 14.7 36.5 14.6 17.0 19.1 15.8 16.5 16.8 18.0 18.3 1622.4 371.8 478.6 22.9 1316.2 856.4 886.2 1417.5 228.8 30.8 289.6 188.5 147.4 936.5 952.5 503.9 6.2 18.3 1879.4 2631.8 88.0 3747.8 52.2 239.4 374.0 1717.8 955.2 499.4 3.6 1310.0 18.5 743.5 853.7 556.2 603.0 253.3 1266.2 276.4 1840.9 37.0 19.3 1755.3 1265.4 1575.0 1124.0 95.6 704.6 1419.1 635.0 67.5 3258.0 170.4 3201.9 49.3 16.1 1802.9 2452.4 484.1 1110.7 1026.6 5267.3 294.9 609.6 24.4 558.8 397.3 579.2 197.4 23.8 216.5 947.7 31.7 2234.9 1021.3 1225.4 1262.8 HMGCS1 HMGCS ENSG00000112972 "3-hydroxy-3-methylglutaryl-CoA synthase 1" Q01581 5 43287470-43313512 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 390.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 511.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 797.7;GAMG: 523.5;HBEC3-KT: 467.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032907, HPA036913, HPA036914" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 470000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032907: AB_2118319, HPA036913: AB_2675380, HPA036914: AB_10671751" "unprognostic (1.31e-1)" "unprognostic (5.12e-3)" "unprognostic (6.82e-3)" "unprognostic (4.59e-2)" "unprognostic (8.39e-2)" "unprognostic (2.49e-2)" "unprognostic (1.03e-1)" "unprognostic (3.14e-2)" "unprognostic (1.27e-2)" "unprognostic (3.13e-1)" "unprognostic (6.40e-3)" "unprognostic (9.15e-2)" "prognostic favorable (3.87e-6)" "unprognostic (1.09e-1)" "unprognostic (9.22e-2)" "unprognostic (3.03e-2)" "unprognostic (2.37e-2)" 19.2 55.2 25.2 27.2 32.9 15.8 40.1 23.0 38.6 56.4 16.8 50.2 93.6 19.8 36.1 137.5 12.4 23.3 16.1 36.1 44.6 32.8 390.2 51.4 21.5 46.5 34.7 21.6 26.6 31.7 15.0 22.5 47.2 40.5 45.4 34.2 53.2 15.7 17.8 85.9 47.2 19.9 24.7 14.8 43.4 33.2 35.3 19.1 23.6 16.7 31.5 18.3 69.5 30.4 103.4 48.8 797.7 93.0 45.8 178.4 54.1 16.2 63.8 22.8 45.2 86.6 146.6 108.4 35.6 23.3 523.5 80.2 199.7 467.2 24.1 23.5 240.7 40.1 45.3 119.3 71.3 88.0 28.0 98.5 56.2 119.5 47.9 14.0 23.7 98.4 73.1 291.7 19.4 48.9 81.3 111.9 143.1 41.7 25.9 57.5 111.9 121.8 357.7 158.2 68.2 33.0 83.6 41.4 25.9 114.5 63.6 116.7 28.3 17.1 85.7 18.0 15.5 38.8 64.0 148.3 15.0 106.2 15.5 3.3 1.8 1.9 2.4 3.3 2.4 3.8 2.6 3.4 3.5 2.9 2.2 3.1 3.0 3.2 3.6 2.9 2.6 1.6 25.2 32.9 23.0 38.6 36.1 44.6 46.5 34.7 47.2 24.7 35.3 30.4 27.8 67.3 172.6 70.5 44.8 108.3 42.3 93.8 68.3 43.6 46.3 30.0 8.9 47.1 79.2 47.8 52.1 22.3 43.3 211.2 13.7 43.0 9.0 47.1 20.2 31.3 92.1 22.3 44.9 59.8 41.1 32.3 100.4 98.6 58.5 56.6 22.1 511.7 25.5 48.8 42.6 101.9 75.3 21.9 38.2 3.2 12.8 27.5 26.6 15.0 49.1 26.4 14.4 53.3 41.8 50.4 132.3 14.3 38.1 149.2 56.8 21.4 51.1 50.1 0.0 40.1 32.8 20.0 8.7 197.9 236.4 44.5 36.4 129.4 62.9 74.5 HOMER3 HOMER-3 ENSG00000051128 "Homer scaffold protein 3" Q9NSC5 19 18929201-18941261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 125.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 76.4;Muller glia cells: 72.6;Proximal tubular cells: 84.2;Theca cells: 322.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 15.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 353.6;THP-1: 420.0;U-266/84: 375.4" "Region enriched" "Detected in all" 6 "cerebellum: 189.2" "Low region specificity" "Detected in all" "CAB032656, HPA040999, CAB079015" Enhanced Supported Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane, Cytoplasmic bodies" "CAB032656: AB_2120801, CAB079015: , HPA040999: AB_2677242" "unprognostic (3.41e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.24e-5)" "unprognostic (1.19e-1)" "unprognostic (2.06e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (4.93e-5)" "unprognostic (1.07e-1)" "unprognostic (8.88e-2)" "unprognostic (5.78e-2)" "unprognostic (1.28e-1)" "unprognostic (2.10e-2)" "unprognostic (5.99e-2)" "unprognostic (3.76e-2)" "unprognostic (2.33e-1)" "unprognostic (1.41e-1)" "unprognostic (4.11e-2)" 33.1 29.6 33.3 9.9 41.9 22.3 26.2 76.9 44.6 31.7 41.1 27.0 7.0 24.6 6.4 15.3 16.7 16.5 25.0 40.4 35.1 52.2 6.1 25.6 7.9 42.3 40.9 20.1 12.4 37.5 8.6 14.7 42.8 21.9 6.0 5.9 27.6 9.4 114.5 35.4 14.4 10.6 39.4 125.1 17.0 9.2 41.6 7.4 49.3 18.6 3.8 29.7 26.0 45.5 112.1 28.5 53.1 44.4 48.3 48.6 26.2 108.1 94.9 106.4 53.4 14.6 41.8 0.9 49.9 122.1 76.1 68.6 18.4 140.4 58.9 4.0 11.0 0.1 9.7 27.5 44.9 21.5 1.7 39.3 89.4 59.0 79.1 113.0 130.3 7.9 3.2 28.6 78.1 30.3 1.9 353.6 27.3 6.1 115.5 55.2 16.2 53.4 38.2 28.3 0.2 44.8 26.6 31.2 78.5 10.2 14.0 420.0 105.3 94.0 42.0 114.5 132.2 274.2 375.4 93.6 148.0 270.6 69.8 0.1 15.0 2.9 0.1 5.3 0.0 2.3 0.8 0.3 1.3 2.7 0.1 0.0 5.8 0.0 1.6 0.2 0.8 4.2 33.3 41.9 76.9 44.6 40.4 35.1 42.3 40.9 42.8 39.4 41.6 45.5 21.7 3.2 0.0 9.4 9.3 11.9 22.4 24.4 6.8 2.2 14.3 22.5 4.1 2.8 8.0 12.9 0.0 1.0 0.6 0.1 11.7 22.9 2.0 4.3 18.7 38.0 1.8 0.4 0.3 13.6 2.4 20.5 0.0 6.3 10.2 34.8 21.8 0.7 76.4 1.7 3.9 0.9 22.4 16.2 7.6 1.7 13.7 32.2 12.4 1.9 8.3 72.6 0.0 1.0 13.4 42.0 0.0 10.9 13.8 25.2 0.0 84.2 3.6 4.1 0.0 14.4 27.8 4.7 6.7 4.2 14.5 1.1 2.5 322.4 0.3 21.4 HRH1 ENSG00000196639 "Histamine receptor H1" P35367 3 11137093-11263557 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.1;Distal enterocytes: 44.9;Glandular and luminal cells: 41.6;Suprabasal keratinocytes: 41.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029740 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Cytosol "HPA029740: AB_10601578" "unprognostic (4.60e-3)" "unprognostic (3.41e-2)" "unprognostic (6.37e-3)" "unprognostic (9.55e-2)" "unprognostic (3.32e-2)" "unprognostic (1.07e-2)" "unprognostic (9.60e-3)" "unprognostic (4.00e-3)" "unprognostic (7.54e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.43e-1)" "unprognostic (1.70e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-2)" "unprognostic (7.19e-2)" "unprognostic (1.20e-1)" 5.7 3.0 5.5 3.1 6.2 0.1 3.4 1.7 6.5 5.0 2.1 8.8 2.7 4.3 4.8 3.3 7.4 7.1 1.5 6.1 5.3 4.2 0.7 4.1 1.2 4.6 2.9 5.9 0.6 0.9 0.5 3.9 3.6 2.4 5.1 0.2 1.8 3.5 0.9 5.1 4.3 5.4 3.2 1.0 1.7 0.8 5.8 1.2 1.2 2.2 1.4 14.3 5.0 4.1 2.6 6.1 0.0 0.0 2.7 28.5 4.2 4.6 15.3 13.3 8.8 1.1 21.8 0.0 13.4 10.6 13.5 17.3 0.0 6.3 17.7 10.1 0.0 1.4 9.7 0.0 8.4 4.5 2.4 10.0 3.7 30.4 10.5 18.4 19.1 0.2 0.0 0.1 5.8 0.0 0.0 1.9 0.0 2.6 5.4 0.4 1.6 0.6 23.2 3.6 0.2 0.0 6.6 4.6 0.0 0.2 0.0 3.5 28.8 14.8 9.4 15.3 23.4 0.0 1.7 0.1 22.5 3.9 13.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 5.5 6.2 1.7 6.5 6.1 5.3 4.6 2.9 3.6 3.2 5.8 4.1 11.5 6.4 1.1 33.3 0.1 46.1 8.9 7.4 6.8 0.0 0.5 0.5 0.5 0.0 19.3 1.8 0.0 0.2 0.0 44.9 0.0 0.6 0.3 20.5 6.9 20.2 3.5 0.0 34.6 0.7 1.0 16.7 8.6 41.6 2.5 28.8 2.5 0.0 27.2 0.0 19.1 15.1 4.1 12.5 12.3 0.2 3.7 9.8 0.0 2.8 0.1 0.0 0.0 2.0 1.1 14.0 21.0 0.0 0.0 6.2 29.1 0.7 5.0 0.2 0.0 6.8 2.8 1.8 3.3 2.2 41.5 0.5 1.0 0.2 15.8 19.3 HTR1B "5-HT1B, 5-HT1DB, HTR1D2, S12" ENSG00000135312 "5-hydroxytryptamine receptor 1B" P28222 6 77460924-77463491 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 9.6;placenta: 6.7;stomach 1: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "pancreatic cancer: 0.7;stomach cancer: 0.8;testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "HUVEC TERT2: 79.4;TIME: 35.1" "Region enriched" "Detected in all" 4 "basal ganglia: 38.6" "Region enhanced" "Detected in many" "basal ganglia: 11.7" HPA028808 Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Plasma membrane" "Endoplasmic reticulum" "HPA028808: AB_2672782" "unprognostic (3.86e-2)" "unprognostic (3.56e-1)" "unprognostic (7.68e-2)" "unprognostic (2.58e-1)" "unprognostic (1.88e-1)" "unprognostic (1.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.11e-1)" "unprognostic (8.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (1.10e-3)" "unprognostic (3.08e-2)" "unprognostic (2.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" 0.8 0.6 2.1 0.4 6.0 0.0 0.2 0.0 3.8 0.8 0.0 0.1 0.1 0.5 0.0 0.0 0.5 0.5 0.0 1.2 2.1 0.5 0.0 0.4 0.0 0.6 4.3 0.3 0.1 0.0 0.2 6.7 1.2 0.2 0.1 0.3 0.2 0.5 0.1 0.2 0.1 0.1 0.1 0.0 5.0 0.5 9.6 0.0 0.2 0.3 0.0 1.3 0.5 1.4 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.4 3.5 1.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.4 0.2 0.6 2.2 1.4 79.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 6.0 0.0 3.8 1.2 2.1 0.6 4.3 1.2 0.1 9.6 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HTR7 5-HT7 ENSG00000148680 "5-hydroxytryptamine receptor 7" P34969 10 90740823-90858039 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, RAS pathway related proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 7.6;parathyroid gland: 13.1;testis: 8.7" "Cell type enhanced" "Detected in some" "Early spermatids: 7.0;Excitatory neurons: 5.9;Inhibitory neurons: 24.2;Spermatocytes: 13.1" "Group enriched" "Detected in some" 5 "cervical cancer: 0.9;head and neck cancer: 3.3;lung cancer: 0.9;urothelial cancer: 1.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.4" "Cell line enhanced" "Detected in many" "HBEC3-KT: 11.3;hTCEpi: 10.1;hTERT-HME1: 33.4;LHCN-M2: 13.5;U-251 MG: 9.6;U-87 MG: 10.2;WM-115: 13.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB022708, HPA073617" Approved Supported Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB022708: , HPA073617: AB_2732228" "unprognostic (1.17e-1)" "unprognostic (1.24e-2)" "unprognostic (4.72e-2)" "unprognostic (1.33e-1)" "unprognostic (5.51e-3)" "unprognostic (1.71e-2)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (1.15e-1)" "unprognostic (4.58e-3)" "unprognostic (3.32e-1)" "unprognostic (1.45e-1)" "unprognostic (2.89e-1)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (1.84e-2)" "unprognostic (6.49e-2)" 0.5 0.2 2.4 0.9 1.4 0.3 0.3 0.0 2.5 0.4 0.4 0.6 0.5 0.2 0.1 0.7 0.2 0.9 0.1 2.7 7.1 0.1 0.4 0.2 0.6 1.5 3.2 0.1 0.2 13.1 0.1 0.3 1.9 0.2 0.9 0.1 0.3 0.1 0.9 0.5 1.4 0.3 0.5 1.1 0.7 8.7 7.6 0.2 0.1 0.5 0.3 2.3 0.6 0.8 0.3 0.0 0.0 0.0 0.2 0.9 0.0 0.7 0.3 0.7 1.0 0.0 1.2 0.0 0.0 0.1 2.0 4.7 1.3 11.3 2.8 0.0 0.2 0.0 0.0 0.0 5.1 0.0 0.6 7.8 10.1 3.3 33.4 6.3 0.0 0.0 0.1 0.0 13.5 0.0 0.0 0.2 1.2 0.0 1.6 1.0 0.1 0.0 0.0 1.2 0.4 0.0 0.5 0.0 5.4 0.6 0.0 0.2 0.3 6.1 0.0 0.1 9.6 0.0 0.0 0.0 10.2 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.4 1.4 0.0 2.5 2.7 7.1 1.5 3.2 1.9 0.5 7.6 0.8 0.1 0.0 0.0 0.7 0.3 0.0 0.2 0.7 0.0 0.0 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.3 0.0 0.0 0.4 5.9 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.4 0.0 1.7 0.0 24.2 0.0 2.0 2.2 0.0 2.7 0.0 2.5 0.0 0.0 0.4 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.1 13.1 1.3 0.0 0.1 0.1 0.2 0.0 0.0 0.3 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 269.3;Granulosa cells: 731.6;Horizontal cells: 625.9;Muller glia cells: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2417.8;ASC TERT1: 889.4;fHDF/TERT166: 862.3;HSkMC: 1581.4;LHCN-M2: 1238.2;U-87 MG: 1004.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" 246.0 81.3 382.1 37.0 436.6 0.5 202.8 422.6 595.7 352.1 316.2 154.8 20.8 197.1 247.1 57.8 122.9 301.2 114.7 377.7 411.4 230.9 226.4 69.9 39.9 427.1 447.0 425.5 55.9 111.8 184.1 281.9 425.3 85.7 51.8 243.6 101.1 114.5 31.1 130.5 73.5 152.3 382.1 54.2 87.3 19.5 423.6 21.2 78.8 80.9 27.3 137.3 188.3 464.2 0.3 45.6 19.4 5.7 2417.8 889.4 0.8 108.3 196.8 44.4 23.6 0.2 0.6 0.0 29.0 862.3 68.6 12.8 7.6 124.4 6.2 0.1 4.9 0.1 65.4 0.3 123.7 0.1 0.9 1581.4 444.6 25.8 205.3 503.6 207.1 0.0 0.1 1.5 1238.2 22.3 0.1 0.7 20.9 0.2 67.6 0.2 1.3 0.4 282.6 2.2 1.2 3.9 272.1 0.2 122.2 91.4 8.6 0.2 136.0 309.9 4.5 141.3 94.1 0.2 0.1 0.3 1004.6 0.2 148.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 382.1 436.6 422.6 595.7 377.7 411.4 427.1 447.0 425.3 382.1 423.6 464.2 55.1 22.4 6.9 116.5 0.9 44.1 32.5 10.8 23.9 53.3 5.4 31.2 26.4 14.3 0.9 64.4 54.2 30.9 1.3 0.0 0.0 2.0 3.5 11.3 76.5 107.0 0.0 2.7 2.2 4.6 164.6 269.3 4.6 14.4 1.3 731.6 57.8 157.8 51.3 625.9 31.2 0.3 8.2 18.1 59.9 4.2 31.7 22.0 46.2 86.2 8.5 373.8 0.0 193.0 112.5 2.7 1.3 77.5 1.9 8.7 0.2 22.6 10.1 150.3 6.6 63.3 140.5 0.2 0.7 7.0 30.5 87.7 7.2 2.5 0.6 11.9 ICOSLG "B7-H2, B7h, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653" ENSG00000160223 "Inducible T cell costimulator ligand" O75144 21 44217014-44240966 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, B-cell activation, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.2;brain: 33.3" "Cell type enhanced" "Detected in many" "B-cells: 28.5;Glandular and luminal cells: 22.7;Langerhans cells: 39.0;monocytes: 21.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 19.9" "CAB026037, HPA029179, CAB079997" Approved Approved "Plasma membrane,Cytoplasmic bodies" NA NA 130000000 "Cluster 37: B-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytoplasmic bodies" "CAB026037: , CAB079997: , HPA029179: AB_2732445" "unprognostic (3.03e-2)" "unprognostic (1.40e-4)" "unprognostic (3.52e-2)" "unprognostic (1.94e-2)" "unprognostic (6.74e-2)" "unprognostic (9.40e-2)" "unprognostic (6.94e-2)" "unprognostic (3.71e-1)" "unprognostic (1.40e-1)" "unprognostic (3.76e-2)" "unprognostic (1.40e-1)" "unprognostic (2.42e-1)" "unprognostic (3.00e-2)" "unprognostic (3.11e-1)" "unprognostic (1.36e-1)" "unprognostic (1.47e-1)" "unprognostic (1.84e-1)" 3.1 3.6 12.1 4.9 21.8 18.2 2.6 10.7 17.9 3.9 0.2 2.1 2.5 1.9 1.4 5.4 3.4 4.1 5.2 11.7 12.4 8.3 3.3 3.1 8.0 18.7 17.9 0.8 2.1 0.7 1.4 3.1 17.1 3.3 1.8 1.4 3.0 1.4 1.5 6.6 3.8 1.3 11.0 4.3 4.9 1.4 18.2 2.6 2.3 1.8 5.5 3.2 3.5 33.3 0.5 4.6 0.2 3.9 1.0 1.5 10.4 1.0 0.9 0.5 0.3 7.9 0.6 19.9 2.9 0.5 1.8 5.8 2.7 1.6 0.3 2.0 2.0 0.6 4.0 2.3 0.9 8.7 14.1 1.4 2.6 1.2 1.3 0.3 1.1 0.7 3.3 1.7 0.3 5.2 0.4 11.4 2.7 13.2 4.8 17.1 1.3 11.6 0.8 10.3 2.0 0.1 12.9 18.2 0.4 1.4 5.1 12.2 1.1 0.6 4.4 0.4 0.4 16.4 12.2 16.2 5.8 8.0 2.5 0.3 0.3 0.2 0.1 0.3 0.1 1.8 0.3 0.1 0.2 2.4 0.3 0.4 0.3 0.2 0.2 0.7 0.1 0.2 12.1 21.8 10.7 17.9 11.7 12.4 18.7 17.9 17.1 11.0 18.2 33.3 1.2 0.0 1.5 0.3 28.5 7.5 5.8 8.4 3.4 1.7 8.7 5.8 0.6 1.5 2.4 9.2 0.0 0.4 2.0 7.9 0.0 2.0 1.9 9.8 2.1 4.6 5.3 0.8 0.0 0.7 1.1 5.6 4.6 22.7 0.0 0.2 1.4 2.8 3.7 0.0 0.0 4.5 8.2 8.8 39.0 4.0 3.1 15.6 8.8 0.0 21.0 1.2 2.1 0.0 0.5 0.8 3.8 10.9 4.7 16.0 3.6 3.5 0.6 1.2 0.0 4.5 6.1 0.1 0.2 4.7 6.5 0.5 2.9 0.3 4.5 7.9 IFIT5 RI58 ENSG00000152778 "Interferon induced protein with tetratricopeptide repeats 5" Q13325 10 89414568-89421605 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 109.1;BJ hTERT+ SV40 Large T+ RasG12V: 128.0" "Low region specificity" "Detected in all" "HPA037957, HPA062180" Uncertain Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA037957: AB_10672499, HPA062180: AB_2684705" "unprognostic (2.17e-1)" "unprognostic (1.85e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (1.67e-3)" "unprognostic (4.19e-2)" "unprognostic (2.88e-2)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (8.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.86e-1)" "unprognostic (3.24e-2)" "unprognostic (1.48e-1)" "unprognostic (3.42e-1)" "unprognostic (2.43e-2)" "unprognostic (1.73e-1)" 13.3 11.6 11.9 11.1 14.3 16.1 9.7 18.7 13.5 11.4 25.0 9.4 9.4 10.2 9.1 7.4 11.2 12.6 14.6 10.8 14.5 14.2 14.1 17.1 13.2 14.7 13.0 14.1 9.2 22.8 3.7 14.6 14.4 9.7 8.9 9.0 12.2 10.5 3.7 5.5 11.1 14.2 19.2 18.6 9.1 6.3 12.5 10.5 10.8 6.4 11.3 12.3 4.6 16.8 41.8 12.5 17.3 56.9 46.7 43.4 3.7 33.2 59.5 109.1 128.0 1.0 19.0 1.8 12.1 38.7 42.8 34.8 20.9 19.3 26.0 17.8 13.1 5.0 8.9 7.8 52.4 0.4 3.1 34.9 7.4 32.0 23.7 30.8 6.2 10.8 0.0 29.4 30.8 7.7 12.6 3.8 2.2 0.0 21.9 11.0 20.0 4.6 23.7 5.1 1.9 11.1 18.2 6.6 51.6 4.7 6.2 3.5 15.5 14.0 10.3 23.2 20.0 3.8 0.6 0.2 24.2 3.3 11.6 24.7 15.7 19.3 13.9 25.6 16.4 21.4 14.7 13.0 14.2 18.1 16.8 14.1 45.2 8.3 32.1 1.3 14.1 12.3 11.9 14.3 18.7 13.5 10.8 14.5 14.7 13.0 14.4 19.2 12.5 16.8 24.8 6.4 14.8 3.6 12.8 8.5 35.7 15.2 13.6 8.3 4.4 4.3 8.9 11.5 12.4 9.2 0.0 6.3 7.5 7.2 11.7 13.7 0.1 11.2 17.1 23.1 4.9 2.1 3.6 9.1 11.5 17.9 6.1 13.3 15.2 6.2 12.1 16.5 11.0 35.3 7.2 5.5 6.1 8.9 6.0 1.0 21.1 10.8 7.2 4.7 12.3 14.6 7.2 4.5 10.2 10.5 5.9 17.3 6.8 21.0 7.5 17.0 9.6 5.3 19.7 15.4 14.2 17.2 14.4 7.7 3.8 4.5 9.3 4.7 2.5 29.1 IFITM1 "9-27, CD225, DSPA2a, IFI17" ENSG00000185885 "Interferon induced transmembrane protein 1" P13164 11 310041-315272 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity, Osteogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 673.8;Endothelial cells: 364.4;Leydig cells: 300.8;Sertoli cells: 276.1;T-cells: 595.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 1494.7;gdT-cell: 2906.3;MAIT T-cell: 2003.4;memory CD4 T-cell: 3120.6;memory CD8 T-cell: 3000.3;naive CD4 T-cell: 2939.3;naive CD8 T-cell: 2996.4;neutrophil: 2741.6;NK-cell: 4679.9;T-reg: 1944.8" "Group enriched" "Detected in all" 7 "granulocytes: 2741.6;NK-cells: 4679.9;T-cells: 3120.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1038.8;BJ hTERT+ SV40 Large T+: 2266.3;BJ hTERT+ SV40 Large T+ RasG12V: 4016.8;HMC-1: 1138.9" "HPA004810, CAB017615" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 58: T-cells - T-cell receptor" "Golgi apparatus" "Plasma membrane, Cytosol" "CAB017615: AB_2264496, HPA004810: AB_1851419" "unprognostic (1.03e-3)" "unprognostic (6.79e-2)" "unprognostic (1.03e-1)" "unprognostic (2.98e-1)" "unprognostic (2.57e-1)" "unprognostic (9.06e-2)" "unprognostic (7.58e-2)" "unprognostic (3.03e-1)" "unprognostic (6.21e-2)" "unprognostic (5.53e-2)" "unprognostic (6.64e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (5.77e-9)" "unprognostic (7.29e-2)" "unprognostic (6.29e-2)" "unprognostic (3.15e-2)" "unprognostic (3.82e-2)" 477.7 102.3 291.8 282.0 303.4 367.1 401.7 293.8 402.1 563.3 321.5 249.0 128.4 314.6 1152.4 147.4 537.4 247.9 368.4 292.6 305.4 317.5 191.4 246.5 417.2 324.8 295.6 607.5 78.8 154.0 145.1 278.5 322.5 190.6 172.0 14.9 199.8 324.3 134.2 164.6 252.4 367.4 308.6 679.7 141.6 56.3 317.5 296.5 263.4 259.3 295.9 307.4 364.7 304.3 125.7 5.5 1011.4 74.5 79.1 279.8 7.4 250.1 1038.8 2266.3 4016.8 3.7 782.2 3.0 157.9 257.1 23.5 269.0 36.5 26.2 52.0 255.3 51.8 125.9 77.5 11.8 668.2 182.8 1138.9 496.3 0.2 26.6 2.6 27.0 4.2 41.1 450.0 880.7 1.7 23.9 85.1 318.2 264.5 0.5 33.5 27.1 3.1 24.5 654.9 0.0 1.0 2.2 122.7 11.9 196.9 138.5 42.1 17.0 8.8 3.8 4.7 1.5 1.1 61.6 44.8 6.8 3.4 253.8 3.1 544.4 62.1 1494.7 2906.3 312.7 2003.4 364.9 3120.6 3000.3 114.2 323.6 2939.3 2996.4 2741.6 4679.9 539.0 33.7 1944.8 4673.8 291.8 303.4 293.8 402.1 292.6 305.4 324.8 295.6 322.5 308.6 317.5 304.3 240.7 35.3 119.4 2.6 88.2 27.9 17.1 70.2 673.8 0.0 13.0 12.6 8.4 2.8 115.3 33.1 0.0 3.3 258.6 13.7 5.9 1.7 1.4 14.6 96.5 364.4 1.2 27.8 0.0 1.4 30.7 236.0 33.6 20.8 18.9 5.6 164.6 24.6 11.8 0.0 0.0 17.3 10.2 10.1 26.8 3.8 300.8 45.4 78.2 42.2 2.1 0.0 126.7 0.0 0.2 0.7 15.0 124.5 141.2 2.3 15.0 1.0 26.0 0.0 276.1 16.4 213.4 0.6 1.5 50.4 14.3 4.0 595.8 2.1 29.2 5.7 IFITM5 "BRIL, DSPA1, fragilis4, Hrmp1" ENSG00000206013 "Interferon induced transmembrane protein 5" A6NNB3 11 298200-299526 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Mineral balance" "Developmental protein" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 4.9;pancreas: 7.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 8 "cerebral cortex: 4.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA039258 Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Cytosol" "HPA039258: AB_10673608" "unprognostic (9.84e-2)" "unprognostic (2.15e-1)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (7.46e-2)" "unprognostic (4.20e-2)" "unprognostic (4.42e-2)" "unprognostic (8.31e-2)" "unprognostic (7.99e-3)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (4.90e-2)" 0.1 0.0 0.0 0.1 0.0 0.7 0.2 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.1 0.1 0.1 0.0 7.3 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNGR1 "CD119, IFNGR" ENSG00000027697 "Interferon gamma receptor 1" P15260 6 137197485-137219449 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 867.1;Club cells: 405.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025889, HPA029213, HPA063871" Approved Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB025889: , HPA029213: AB_10601023, HPA063871: AB_2685138" "unprognostic (1.73e-1)" "unprognostic (8.86e-2)" "unprognostic (9.85e-3)" "unprognostic (1.71e-1)" "unprognostic (6.55e-2)" "unprognostic (1.25e-1)" "unprognostic (4.05e-1)" "unprognostic (6.97e-2)" "unprognostic (9.86e-2)" "unprognostic (1.57e-2)" "unprognostic (4.09e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (5.48e-4)" "unprognostic (1.58e-1)" "unprognostic (2.87e-2)" "unprognostic (1.81e-2)" "unprognostic (5.38e-3)" 155.5 59.3 54.6 131.5 57.8 146.2 121.4 64.5 72.1 74.1 56.8 74.7 97.9 58.1 67.4 65.0 55.7 88.4 103.7 53.1 59.9 44.4 104.0 153.8 140.2 71.9 60.3 43.3 44.5 47.4 26.3 86.1 75.9 53.2 74.4 40.4 57.7 57.4 58.3 66.2 101.2 75.9 69.2 165.9 51.3 27.9 59.9 69.2 58.3 75.5 135.2 112.6 58.0 85.0 23.2 23.4 25.1 33.4 166.8 86.7 23.0 67.0 90.0 38.0 53.3 148.7 39.8 24.5 99.2 36.1 55.1 130.0 24.1 62.6 51.5 49.4 37.4 36.1 23.3 192.9 97.3 112.9 46.6 195.9 232.6 33.3 51.4 36.1 48.7 29.1 32.0 34.9 29.2 27.7 17.7 47.0 22.0 191.9 18.6 51.3 28.4 32.1 65.5 104.4 27.4 39.5 77.3 41.9 57.5 47.8 15.5 68.7 71.1 36.2 27.7 48.5 31.8 25.3 25.5 23.8 19.4 69.2 36.5 158.6 518.4 356.3 106.9 502.6 224.7 91.3 60.0 90.0 309.4 98.3 39.2 43.1 736.0 48.4 375.6 85.1 48.0 519.3 54.6 57.8 64.5 72.1 53.1 59.9 71.9 60.3 75.9 69.2 59.9 85.0 298.7 80.1 59.9 21.5 76.4 127.6 177.6 867.1 84.2 15.4 49.8 37.3 49.6 37.1 405.7 27.6 12.5 78.5 240.8 111.0 7.9 74.2 11.6 91.4 52.7 110.7 13.1 25.7 21.4 101.4 67.1 94.7 33.6 112.8 63.3 10.3 62.8 56.5 149.8 10.1 24.2 25.5 270.6 326.2 220.0 6.1 44.1 261.7 49.8 147.1 138.4 23.5 52.5 25.1 44.9 76.0 57.6 49.2 74.5 129.6 82.0 17.2 150.6 28.1 13.1 45.7 75.7 14.6 22.4 47.3 113.2 209.9 121.5 48.3 33.9 140.2 IGFLR1 "FLJ22573, TMEM149, U2AF1L4" ENSG00000126246 "IGF like family receptor 1" Q9H665 19 35738801-35742453 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 49.9" "Cell type enhanced" "Detected in many" "dendritic cells: 29.9;granulocytes: 38.7;Langerhans cells: 33.7;Macrophages: 28.8;monocytes: 115.6;Plasma cells: 42.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 899.7" "Lineage enriched" "Detected in all" 4 "dendritic cells: 899.7" "Cell line enhanced" "Detected in many" "HMC-1: 32.9;Karpas-707: 26.0;U-266/70: 34.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA012369, HPA070778" Uncertain Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Plasma membrane" "HPA012369: AB_1858095, HPA070778: " "unprognostic (5.97e-3)" "prognostic favorable (6.55e-4)" "unprognostic (1.94e-1)" "unprognostic (5.42e-2)" "unprognostic (8.31e-3)" "unprognostic (2.34e-4)" "unprognostic (6.71e-2)" "unprognostic (1.74e-2)" "unprognostic (1.87e-2)" "prognostic favorable (1.59e-5)" "unprognostic (1.44e-3)" "unprognostic (3.52e-1)" "unprognostic (8.72e-12)" "unprognostic (2.74e-1)" "unprognostic (1.22e-1)" "unprognostic (2.29e-1)" "unprognostic (3.32e-3)" 7.6 10.9 6.1 19.5 6.8 14.4 6.2 6.0 9.3 4.9 6.0 6.5 6.1 3.4 5.5 4.0 6.4 6.1 4.5 5.9 11.1 14.0 49.9 11.3 33.0 9.1 6.8 4.4 9.3 1.4 5.5 4.5 7.4 6.2 6.4 4.6 7.8 1.5 4.5 4.4 13.2 4.4 5.6 28.6 7.9 6.7 7.1 12.6 7.2 2.1 23.2 7.3 3.5 7.5 2.2 10.0 3.5 8.3 1.1 1.7 2.0 1.5 1.1 1.8 4.7 3.0 2.4 4.0 3.2 0.7 0.6 1.6 2.0 2.1 0.9 3.3 5.0 15.0 3.4 9.1 2.8 1.7 32.9 2.7 1.3 3.5 0.8 0.6 1.9 7.7 4.9 26.0 0.5 7.4 5.1 16.7 1.6 9.4 2.7 6.0 3.3 8.3 1.7 3.2 2.4 4.5 3.4 2.4 1.8 1.3 3.4 7.8 0.5 4.2 2.0 2.6 4.0 34.0 7.5 2.8 4.9 5.8 3.0 147.9 190.9 184.1 94.2 167.7 106.6 169.3 107.3 88.8 253.2 172.1 95.8 77.0 208.6 144.9 125.3 899.7 136.3 139.5 6.1 6.8 6.0 9.3 5.9 11.1 9.1 6.8 7.4 5.6 7.1 7.5 0.3 0.0 13.5 2.6 24.5 0.6 0.3 0.0 0.0 0.4 1.3 1.3 1.2 1.5 5.0 0.0 0.0 0.6 29.9 1.2 1.9 1.9 0.0 0.8 0.6 0.8 3.0 6.1 0.3 4.2 1.8 0.9 1.1 0.7 38.7 0.6 2.2 20.3 14.6 0.0 0.4 1.8 0.0 15.7 33.7 0.6 0.0 28.8 5.4 1.9 115.6 2.7 12.3 2.5 1.0 1.4 0.3 0.0 42.1 0.2 0.9 10.8 3.6 0.4 0.0 1.0 0.9 0.4 0.5 1.9 0.9 0.3 20.8 0.4 2.4 0.0 IKZF5 "FLJ22973, Pegasus, ZNFN1A5" ENSG00000095574 "IKAROS family zinc finger 5" Q9H5V7 10 122990807-123008812 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015297, HPA051574" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA015297: AB_1855183, HPA051574: AB_2681538" "unprognostic (2.42e-1)" "unprognostic (1.08e-1)" "unprognostic (4.64e-2)" "unprognostic (2.76e-2)" "unprognostic (1.44e-2)" "unprognostic (1.66e-3)" "unprognostic (2.68e-1)" "unprognostic (9.14e-3)" "unprognostic (5.43e-2)" "unprognostic (2.99e-1)" "unprognostic (6.88e-2)" "unprognostic (1.63e-2)" "unprognostic (3.98e-3)" "unprognostic (4.17e-2)" "unprognostic (6.03e-2)" "unprognostic (6.96e-2)" "unprognostic (3.15e-2)" 8.3 8.5 8.7 7.3 11.5 34.0 12.2 10.2 15.1 8.8 5.9 7.6 6.6 9.3 9.7 7.2 8.4 6.1 7.1 8.3 10.3 8.7 12.2 8.2 11.1 10.4 10.4 13.9 11.1 9.3 10.1 8.1 11.2 8.3 7.1 13.6 8.4 6.0 9.7 11.3 8.5 7.1 10.0 9.2 7.9 10.5 9.8 10.5 10.0 9.4 9.6 7.3 8.4 17.7 7.5 3.7 7.3 12.5 11.5 10.5 7.9 6.2 13.3 8.1 9.8 6.0 8.6 18.8 4.5 7.6 4.4 10.1 13.0 9.3 11.9 10.6 11.5 12.1 6.0 9.0 7.6 14.8 10.6 8.3 12.5 9.7 20.8 11.1 9.0 12.3 16.9 12.2 8.8 5.5 13.6 16.1 6.7 5.6 5.1 10.9 9.1 10.8 6.7 5.1 7.9 7.1 5.1 6.3 12.2 5.8 5.2 9.3 9.3 5.8 4.9 8.6 10.1 11.4 6.6 17.6 7.4 25.5 3.5 6.0 4.1 5.7 5.8 5.3 6.8 4.0 5.3 5.7 4.5 4.7 7.2 8.4 4.0 6.7 5.6 3.1 7.5 4.3 8.7 11.5 10.2 15.1 8.3 10.3 10.4 10.4 11.2 10.0 9.8 17.7 11.2 12.8 13.1 8.8 16.0 32.2 11.0 7.2 20.5 12.7 23.8 15.0 15.6 8.6 11.3 5.5 14.6 5.8 20.5 7.7 9.8 5.1 8.6 12.0 13.2 11.5 18.0 12.4 10.9 5.3 5.7 15.6 7.7 20.7 17.1 11.3 9.7 15.7 6.5 11.8 13.0 9.2 4.1 10.6 11.4 3.7 13.4 11.0 16.0 17.8 8.9 9.0 17.5 13.0 30.9 4.7 4.9 10.5 14.2 16.1 7.4 11.4 10.9 14.1 13.1 14.3 11.6 22.8 22.3 20.4 32.4 14.4 19.3 7.0 6.7 11.9 IL10RA "CD210, CD210a, CDW210A, HIL-10R, IL10R" ENSG00000110324 "Interleukin 10 receptor subunit alpha" Q13651 11 117986370-118003037 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 63.6;lymphoid tissue: 73.7" "Cell type enhanced" "Detected in many" "dendritic cells: 87.5;Extravillous trophoblasts: 93.0;Kupffer cells: 190.7;Langerhans cells: 145.0;Macrophages: 128.6;monocytes: 175.7;NK-cells: 110.2;Plasma cells: 129.5;T-cells: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.5;HDLM-2: 76.6;Karpas-707: 27.7;RPMI-8226: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065647, HPA069086" Supported "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "HPA065647: , HPA069086: " "unprognostic (1.01e-2)" "unprognostic (2.07e-3)" "unprognostic (1.58e-2)" "unprognostic (7.08e-2)" "unprognostic (8.27e-2)" "prognostic favorable (4.47e-4)" "unprognostic (5.27e-2)" "unprognostic (4.84e-2)" "unprognostic (7.70e-3)" "unprognostic (5.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.83e-1)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.82e-1)" "unprognostic (8.43e-3)" "unprognostic (2.19e-1)" "unprognostic (1.27e-1)" 13.9 8.9 4.7 39.8 4.9 63.6 6.1 4.4 7.0 5.6 4.9 12.0 8.0 3.5 2.7 6.4 5.2 17.9 5.3 4.2 5.9 4.1 13.1 23.8 51.7 6.9 5.1 3.1 2.4 2.6 3.6 14.2 5.5 4.7 14.5 0.5 5.2 3.2 1.7 3.2 24.8 10.4 6.0 73.7 9.2 1.9 5.3 16.9 4.2 3.3 32.4 20.7 3.7 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 0.2 0.0 0.7 0.0 0.5 0.0 0.0 76.6 0.0 0.2 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 5.6 27.7 0.0 0.0 0.4 6.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.1 0.0 5.6 1.0 8.0 0.0 11.4 0.0 3.3 48.9 2.4 52.8 68.6 38.3 12.6 51.0 62.1 44.7 6.2 17.9 33.3 3.4 70.2 58.6 17.3 88.7 84.1 4.7 4.9 4.4 7.0 4.2 5.9 6.9 5.1 5.5 6.0 5.3 7.5 2.2 6.4 16.0 0.3 52.8 5.7 0.4 0.0 5.7 0.1 1.0 1.9 2.7 0.0 1.3 0.0 0.0 1.3 87.5 0.5 0.0 0.2 0.1 0.4 0.5 4.9 0.0 9.3 0.8 0.8 93.0 2.3 6.6 0.7 12.6 0.0 3.6 1.4 60.4 0.0 1.2 0.0 0.0 190.7 145.0 0.5 0.3 128.6 17.8 22.5 175.7 0.4 110.2 0.0 0.6 0.1 0.1 0.0 129.5 0.0 0.0 1.0 1.5 0.1 0.0 1.6 2.7 0.1 0.3 1.2 4.1 3.3 105.5 0.0 0.7 0.4 IL17RB "CRL4, EVI27, IL17BR, IL17RH1" ENSG00000056736 "Interleukin 17 receptor B" Q9NRM6 3 53846568-53865794 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.9;kidney: 59.8;liver: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3;Enteroendocrine cells: 29.2;Oligodendrocyte precursor cells: 37.7;Proximal tubular cells: 78.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 20.2;Hep G2: 59.5;OE19: 46.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005482 Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "HPA005482: AB_1234567" "unprognostic (1.85e-3)" "unprognostic (4.22e-3)" "unprognostic (1.60e-3)" "unprognostic (2.86e-2)" "unprognostic (1.42e-2)" "unprognostic (6.20e-3)" "unprognostic (1.62e-2)" "unprognostic (6.09e-3)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" "unprognostic (4.27e-2)" "prognostic favorable (6.61e-4)" "unprognostic (8.10e-2)" "unprognostic (6.97e-2)" "unprognostic (5.29e-1)" "unprognostic (7.15e-3)" 0.9 2.0 20.2 2.3 21.4 0.5 5.7 22.7 28.9 18.1 16.6 6.8 5.8 5.1 0.7 1.7 3.3 2.4 2.7 19.4 20.2 59.8 33.3 3.8 2.5 18.7 19.9 1.5 7.8 1.1 4.2 0.9 19.0 2.4 6.9 4.8 4.9 0.6 1.3 2.2 5.9 0.8 18.9 1.2 3.6 2.5 23.2 0.3 2.9 0.2 0.7 0.8 1.3 23.6 1.5 3.1 4.5 3.4 0.1 0.0 7.1 3.1 0.1 0.1 0.0 20.2 1.4 4.6 1.0 1.0 1.7 0.8 12.2 0.0 0.0 1.6 3.5 6.0 6.1 59.5 0.0 5.6 3.2 0.0 0.0 0.0 0.0 3.8 0.0 1.6 4.9 2.1 0.1 4.2 0.9 2.3 12.1 46.2 2.6 1.7 1.9 5.3 1.4 5.3 6.4 3.7 10.1 2.4 1.9 3.3 9.2 2.0 2.5 3.0 3.3 2.6 3.9 4.7 5.6 2.9 2.7 3.3 1.7 1.3 0.2 0.0 0.2 0.2 0.1 0.1 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.3 0.9 0.1 20.2 21.4 22.7 28.9 19.4 20.2 18.7 19.9 19.0 18.9 23.2 23.6 0.2 0.0 4.1 48.3 0.2 0.3 2.0 0.0 0.0 0.1 8.2 4.4 4.1 17.2 1.3 0.0 0.0 1.4 0.3 4.3 9.8 4.8 1.0 0.5 1.0 0.2 29.2 0.0 0.5 1.6 1.0 0.6 4.6 1.7 2.5 0.4 0.4 13.1 0.1 0.0 2.5 8.7 2.0 0.0 1.1 0.7 1.2 1.2 0.0 1.9 0.0 4.4 0.0 37.7 4.3 1.8 3.0 0.4 0.0 4.4 2.9 78.0 0.0 0.1 0.0 0.3 0.5 0.4 1.0 0.0 0.1 0.4 0.9 0.0 10.2 0.6 IL1RL1 "DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1" ENSG00000115602 "Interleukin 1 receptor like 1" Q01638 2 102311502-102352037 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 126.4;lung: 162.0;placenta: 199.8" "Cell type enriched" "Detected in many" 9 "granulocytes: 501.5" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 64 "basophil: 38.3;eosinophil: 29.3" "Lineage enriched" "Detected in single" 72 "granulocytes: 38.3" "Group enriched" "Detected in some" 6 "HHSteC: 245.1;HMC-1: 373.7;HUVEC TERT2: 185.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007406, HPA007917" Uncertain Supported "Plasma membrane,Focal adhesion sites,Cytosol" "Secreted to blood" NA NA 19100000 3100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA007406: AB_1079128, HPA007917: AB_1079129" "unprognostic (7.25e-2)" "unprognostic (9.72e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (5.28e-2)" "unprognostic (1.98e-2)" "unprognostic (3.25e-3)" "unprognostic (2.07e-1)" "unprognostic (2.77e-1)" "unprognostic (4.50e-2)" "unprognostic (8.58e-2)" "unprognostic (9.74e-2)" "unprognostic (1.44e-1)" "unprognostic (1.32e-2)" "unprognostic (1.60e-2)" "unprognostic (1.17e-1)" "unprognostic (4.60e-3)" 22.3 30.3 7.5 3.1 9.8 0.7 14.7 7.8 11.0 3.6 12.2 5.2 1.7 2.5 0.6 4.4 2.6 14.7 24.7 7.2 8.2 126.4 16.0 162.0 0.7 7.6 7.7 1.1 4.8 0.8 5.7 199.8 7.7 4.9 3.4 2.8 1.8 4.6 2.5 4.3 8.0 3.7 8.0 1.4 25.1 0.5 9.6 1.3 4.1 0.7 0.8 6.5 3.9 8.9 0.9 0.2 0.7 0.1 15.1 0.6 0.3 0.5 0.7 0.4 0.6 0.3 0.5 0.5 0.7 0.2 0.2 1.4 0.2 6.3 0.4 0.2 0.1 45.7 0.8 0.8 245.1 1.9 373.7 5.1 1.5 6.2 40.0 0.6 185.5 0.2 0.9 0.8 0.7 0.4 0.6 8.7 0.3 0.4 0.7 0.3 0.2 0.2 1.0 0.3 0.6 0.4 0.5 0.3 0.2 0.4 0.3 0.1 15.4 0.5 0.5 3.5 0.5 0.1 0.3 0.4 0.7 0.6 0.5 38.3 0.0 29.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 7.5 9.8 7.8 11.0 7.2 8.2 7.6 7.7 7.7 8.0 9.6 8.9 22.6 9.6 13.1 0.0 0.1 8.5 20.3 0.4 0.0 0.0 0.3 0.1 2.7 0.0 7.7 1.8 0.0 0.0 3.3 0.1 0.0 3.2 0.4 1.1 14.8 49.7 0.0 1.3 0.2 0.5 0.1 54.5 0.0 2.5 501.5 0.0 26.4 0.7 0.0 0.0 0.2 0.0 0.0 0.3 19.1 1.3 0.9 3.0 3.6 0.0 0.0 0.0 0.0 0.5 0.1 37.2 0.0 0.0 3.2 15.7 0.0 0.0 6.6 0.3 39.5 1.5 37.7 0.0 0.0 0.0 5.1 0.0 31.5 0.0 0.0 16.4 IL4R CD124 ENSG00000077238 "Interleukin 4 receptor" P24394 16 27313668-27364778 "Cancer-related genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 92.0;granulocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 78.1" "Group enriched" "Detected in all" 5 "B-cells: 78.1;granulocytes: 31.1" "Cell line enhanced" "Detected in many" "Daudi: 124.2;HBEC3-KT: 115.0;HDLM-2: 110.6;U-698: 119.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004451, HPA050124, HPA070380" Enhanced Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 38500 110000 "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Plasma membrane" "Centriolar satellite" "CAB004451: AB_626889, HPA050124: AB_2681026, HPA070380: " "unprognostic (6.80e-2)" "unprognostic (6.35e-2)" "unprognostic (2.84e-1)" "prognostic favorable (6.43e-4)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (2.33e-2)" "unprognostic (1.95e-3)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.49e-2)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (9.58e-2)" 49.4 45.2 22.7 82.3 19.7 103.4 34.1 19.2 22.0 39.7 21.4 97.0 27.3 35.8 5.9 70.8 42.3 41.2 34.2 18.7 21.0 50.8 116.0 119.2 117.1 29.4 22.2 14.3 29.8 31.7 14.9 39.3 24.0 49.9 35.6 2.4 20.5 25.6 9.3 24.4 55.7 37.3 25.5 90.0 55.0 15.5 25.3 22.3 24.2 6.6 89.6 63.2 45.4 23.8 39.9 10.1 6.4 13.1 3.1 14.1 14.3 24.7 27.3 9.3 7.7 20.4 105.2 124.2 30.1 38.5 18.3 39.7 7.3 115.0 8.2 110.6 4.0 22.6 6.6 31.6 40.8 6.1 61.7 23.5 45.0 44.2 26.5 48.7 50.7 6.8 10.5 9.8 15.0 17.3 0.7 18.8 8.0 34.2 9.1 0.4 47.5 10.2 42.9 43.2 1.9 0.6 3.7 24.7 5.0 15.6 8.2 23.5 81.0 21.0 9.8 19.0 17.6 6.1 2.1 119.7 2.1 21.1 0.3 1.4 7.2 13.0 4.2 3.1 3.4 25.8 6.9 4.4 4.1 78.1 10.0 5.0 31.1 8.2 1.8 4.8 5.3 5.8 22.7 19.7 19.2 22.0 18.7 21.0 29.4 22.2 24.0 25.5 25.3 23.8 30.5 28.9 49.2 0.7 92.0 13.3 43.3 34.9 26.2 0.3 9.4 14.2 2.4 34.3 33.4 1.8 0.0 17.6 29.8 60.0 0.0 39.5 0.3 6.6 2.2 39.0 23.4 5.2 1.7 32.3 3.8 17.2 32.1 17.2 110.8 0.7 62.8 45.9 27.2 0.0 0.6 35.5 8.2 30.6 29.9 0.8 0.3 34.3 14.2 38.4 39.3 0.0 7.2 0.5 0.7 49.3 28.7 0.0 13.4 37.7 24.0 1.2 28.5 0.2 39.5 16.4 20.0 0.8 3.3 23.8 14.9 24.9 38.3 0.2 16.7 46.9 IL6ST "CD130, GP130, sGP130" ENSG00000134352 "Interleukin 6 signal transducer" P40189 5 55935095-55995022 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 580.3;Hepatic stellate cells: 808.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 16.7" "Lineage enriched" "Detected in many" 4 "T-cells: 16.7" "Cell line enhanced" "Detected in many" "ASC TERT1: 151.3;BJ hTERT+: 175.2;HHSteC: 155.1;HSkMC: 135.1;TIME: 147.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010558, CAB025784" Approved Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 160000000 "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Golgi apparatus" "CAB025784: , HPA010558: AB_1078439" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (3.95e-2)" "unprognostic (8.93e-2)" "unprognostic (3.99e-2)" "unprognostic (5.18e-2)" "unprognostic (9.53e-3)" "unprognostic (1.89e-2)" "unprognostic (2.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (3.69e-2)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" 67.1 46.0 26.8 14.1 31.0 9.6 51.3 30.9 36.7 43.0 21.3 33.9 4.2 35.2 18.5 18.4 34.2 23.6 35.1 23.5 31.4 30.0 77.6 53.3 15.9 32.1 27.0 36.9 21.9 39.6 22.5 101.7 35.9 32.6 14.3 28.6 31.9 29.9 41.0 17.8 31.1 28.7 35.1 34.7 27.8 8.9 25.3 23.6 40.4 34.7 16.2 37.7 35.1 42.9 14.4 35.6 9.4 18.8 75.5 151.3 22.3 54.5 175.2 44.1 62.4 40.5 16.3 1.1 33.7 52.5 71.6 7.8 9.8 19.2 84.1 1.6 8.5 4.6 20.1 14.2 155.1 0.4 6.2 135.1 11.1 103.1 42.7 43.6 101.8 1.9 3.7 51.0 47.0 2.9 0.7 0.8 1.5 1.8 10.1 1.1 22.5 14.4 22.5 12.1 3.8 5.9 26.6 5.7 19.7 13.7 29.5 3.1 147.8 12.4 10.1 44.5 24.6 14.6 8.2 0.5 28.9 1.1 31.1 0.0 3.9 0.1 0.7 3.4 0.3 0.8 3.7 0.8 2.1 0.4 16.7 4.8 0.6 0.8 0.5 1.9 4.1 4.0 26.8 31.0 30.9 36.7 23.5 31.4 32.1 27.0 35.9 35.1 25.3 42.9 221.6 134.6 149.8 59.4 30.0 103.9 98.0 60.6 71.2 56.5 202.4 81.3 81.5 124.4 105.4 68.0 35.5 77.9 33.1 34.5 7.9 85.3 12.3 76.4 227.6 256.2 19.8 41.1 25.7 62.0 75.5 285.5 59.1 580.3 32.9 58.6 808.5 219.8 56.0 16.8 70.0 34.1 46.8 93.7 99.1 16.7 105.9 60.3 80.0 188.3 45.8 190.8 7.2 75.4 64.2 80.8 35.6 130.5 100.6 163.9 33.6 52.2 80.3 39.3 98.6 158.7 150.3 54.4 38.6 44.9 83.5 101.8 75.5 228.7 17.1 106.1 IL7R "CD127, IL7RA" ENSG00000168685 "Interleukin 7 receptor" P16871 5 35852695-35879603 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 183.7" "Group enriched" "Detected in many" 4 "monocytes: 271.8;T-cells: 973.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 102.1;MAIT T-cell: 369.5;memory CD4 T-cell: 213.8;memory CD8 T-cell: 151.1;naive CD4 T-cell: 179.5;naive CD8 T-cell: 124.6;NK-cell: 113.2" "Group enriched" "Detected in all" 33 "NK-cells: 113.2;T-cells: 369.5" "Cell line enhanced" "Detected in many" "BJ: 99.8;BJ hTERT+ SV40 Large T+: 87.7;fHDF/TERT166: 187.7;HBF TERT88: 168.3;REH: 406.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010215, HPA067550" Supported "Plasma membrane" "Intracellular and membrane" NA NA 610000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "CAB010215: AB_673727, HPA067550: " "unprognostic (2.93e-3)" "unprognostic (3.38e-2)" "unprognostic (3.82e-3)" "unprognostic (5.58e-3)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (2.51e-3)" "unprognostic (5.53e-2)" "unprognostic (1.12e-1)" "unprognostic (9.29e-3)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (1.76e-2)" "unprognostic (5.64e-2)" "unprognostic (3.27e-3)" "unprognostic (2.22e-1)" "unprognostic (1.78e-1)" 11.2 14.4 1.5 137.6 1.8 14.0 20.4 7.4 2.7 12.0 1.0 17.3 15.0 3.9 1.6 11.0 5.7 32.4 2.2 2.0 2.5 4.5 12.5 63.9 139.4 1.8 0.5 2.2 5.3 0.8 1.7 2.9 1.6 8.7 20.4 0.9 3.3 3.1 4.1 3.8 56.8 5.6 0.6 70.1 34.1 4.7 4.4 183.7 7.6 1.7 123.0 48.0 7.1 6.2 0.6 0.4 0.7 0.4 0.7 0.6 0.6 99.8 50.6 87.7 51.3 0.5 0.6 9.6 0.3 187.7 15.9 16.0 0.2 6.0 168.3 8.6 1.1 3.2 10.3 0.0 1.5 0.6 7.2 1.6 0.0 18.7 4.3 2.4 2.6 0.7 0.7 0.9 71.3 0.2 2.3 1.0 0.3 0.3 4.6 406.2 5.2 0.6 0.0 5.3 0.4 0.2 15.9 1.7 0.2 0.3 0.6 0.4 7.0 34.5 58.4 14.8 13.4 0.6 0.2 10.4 17.4 9.2 27.8 4.3 1.6 1.0 102.1 1.2 369.5 1.5 213.8 151.1 0.7 2.1 179.5 124.6 7.3 113.2 1.5 1.8 39.7 87.7 1.5 1.8 7.4 2.7 2.0 2.5 1.8 0.5 1.6 0.6 4.4 6.2 8.9 16.0 16.0 0.0 47.4 11.6 2.7 0.0 5.2 0.0 8.6 6.1 4.9 0.0 2.5 0.0 0.0 0.2 136.0 0.6 0.0 1.0 0.1 1.1 0.4 13.2 0.0 16.4 0.0 2.0 0.2 11.6 53.5 1.2 19.6 0.2 13.2 4.4 10.6 0.0 0.0 0.5 0.0 10.6 98.5 0.8 0.0 58.8 21.4 2.8 271.8 0.0 11.3 0.0 0.0 0.1 1.4 0.0 93.5 1.4 0.0 0.8 5.8 0.0 0.0 5.5 7.9 0.2 0.1 1.5 10.4 0.3 973.8 0.4 0.4 3.5 ILK ENSG00000166333 "Integrin linked kinase" Q13418 11 6603708-6610874 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004041, HPA048437" Enhanced Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 30000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB004041: AB_2127050, HPA048437: AB_2680391" "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "unprognostic (5.26e-2)" "unprognostic (2.12e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-3)" "unprognostic (5.25e-3)" "unprognostic (1.49e-2)" "unprognostic (9.65e-2)" "unprognostic (2.64e-1)" "unprognostic (8.12e-2)" "prognostic favorable (2.44e-4)" "unprognostic (4.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.42e-1)" "unprognostic (6.36e-3)" 108.0 77.2 49.8 85.1 52.4 43.7 91.8 51.7 50.6 151.6 55.0 398.2 66.4 359.1 81.8 115.5 164.2 88.0 175.9 47.4 50.7 78.8 65.9 107.9 72.4 51.8 50.6 101.0 89.3 73.2 47.1 98.8 50.9 182.7 116.8 28.3 69.5 412.2 90.8 61.5 117.4 364.7 51.1 95.5 149.7 26.5 53.7 45.8 72.0 92.0 70.5 226.7 118.8 51.9 127.8 94.4 148.9 51.8 224.8 159.4 67.2 182.2 360.0 211.9 256.0 102.7 145.7 47.0 47.0 304.1 206.9 99.5 84.4 155.6 213.0 83.5 74.3 69.1 84.9 82.8 150.8 55.9 74.7 153.2 72.8 143.8 108.9 217.7 206.9 40.5 63.7 55.0 282.8 97.1 49.4 97.4 94.3 107.5 110.8 51.0 77.8 50.5 160.3 100.8 25.6 57.4 86.0 118.4 103.6 144.0 82.2 62.2 238.8 263.9 118.0 111.1 90.7 38.9 25.9 67.1 195.6 82.8 125.3 314.9 260.0 417.6 127.3 258.1 124.9 96.9 114.4 122.3 242.7 92.9 70.2 88.5 165.5 257.8 254.8 98.5 142.8 402.8 49.8 52.4 51.7 50.6 47.4 50.7 51.8 50.6 50.9 51.1 53.7 51.9 79.5 44.8 17.9 24.2 33.6 50.5 73.7 100.6 24.5 21.5 43.1 68.2 0.5 70.1 49.7 57.0 8.4 119.8 46.0 71.9 58.7 136.1 64.6 33.2 78.1 69.4 37.9 53.7 14.6 125.0 177.7 83.2 50.4 52.5 30.4 41.6 76.4 31.4 127.4 8.4 17.1 50.1 69.2 51.5 97.7 143.7 71.4 115.9 85.4 30.9 143.0 54.3 77.2 15.6 15.3 117.1 60.0 147.4 35.1 42.0 74.5 98.6 31.0 32.9 157.8 53.3 165.8 31.7 17.1 32.3 43.2 110.0 49.3 65.0 50.1 43.9 INSR CD220 ENSG00000171105 "Insulin receptor" P06213 19 7112255-7294414 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Carbohydrate metabolism" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 9.8;granulocytes: 5.9;monocytes: 12.5" "Cell line enhanced" "Detected in many" "Karpas-707: 54.9;U-266/70: 40.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036302, HPA036303" Uncertain Approved "Vesicles,Plasma membrane" NA Yes 190000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA036302: AB_2675048, HPA036303: " "unprognostic (4.64e-2)" "unprognostic (2.42e-1)" "unprognostic (9.65e-3)" "unprognostic (9.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.15e-2)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (1.97e-1)" "unprognostic (3.05e-1)" "unprognostic (9.29e-2)" "unprognostic (1.86e-1)" "unprognostic (6.33e-2)" "unprognostic (3.45e-3)" "unprognostic (2.43e-1)" "unprognostic (2.75e-1)" "unprognostic (8.82e-2)" 13.0 22.6 12.5 2.8 16.8 5.6 13.0 17.3 12.8 14.6 18.8 15.0 10.0 18.4 6.3 4.1 16.9 8.2 26.3 10.0 12.2 21.8 33.0 7.2 2.3 18.3 16.3 39.9 64.2 13.0 16.3 7.4 18.7 15.2 10.4 6.5 16.9 9.9 23.5 11.5 12.2 11.5 14.1 48.2 12.5 5.4 16.6 2.7 14.5 13.3 3.5 12.3 9.2 22.5 6.2 3.2 3.6 5.7 18.8 6.1 11.1 3.5 2.9 1.6 1.6 8.4 7.0 9.0 8.2 6.8 4.0 1.6 8.9 1.4 1.2 0.0 6.4 0.0 2.3 22.6 8.2 4.3 6.7 10.0 4.5 0.2 4.9 4.2 3.8 4.8 9.5 54.9 1.8 3.2 3.1 7.8 3.3 3.8 5.2 29.0 2.1 7.6 0.1 27.8 6.6 5.2 6.5 3.8 3.3 6.4 1.4 21.6 3.6 3.4 2.1 8.2 5.1 40.4 23.9 20.2 4.3 7.3 0.0 2.7 8.6 5.9 0.2 8.8 0.3 0.8 0.3 0.1 9.8 1.1 0.7 0.1 1.9 1.0 12.5 8.2 0.0 1.6 12.5 16.8 17.3 12.8 10.0 12.2 18.3 16.3 18.7 14.1 16.6 22.5 75.6 48.1 34.7 64.9 10.6 64.9 63.6 34.7 8.0 40.4 134.0 76.2 92.1 137.2 83.3 62.5 79.2 17.8 6.7 124.1 15.6 55.1 4.7 26.8 106.8 123.9 163.6 25.0 68.3 78.7 53.7 43.7 20.4 42.1 3.8 168.4 255.2 246.0 9.2 38.7 100.8 97.3 32.6 49.0 31.1 9.0 96.3 35.0 51.6 62.8 24.2 31.6 0.0 62.8 183.5 50.7 68.8 245.3 21.8 107.9 122.9 114.1 65.3 23.6 59.2 37.6 44.2 5.2 3.6 3.2 68.8 38.3 4.7 81.4 65.2 130.0 IQGAP1 "HUMORFA01, KIAA0051, p195, SAR1" ENSG00000140575 "IQ motif containing GTPase activating protein 1" P46940 15 90388242-90502239 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013302, HPA014055" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 1500000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cell Junctions" "CAB013302: AB_2533146, HPA014055: AB_1851856" "unprognostic (2.83e-1)" "unprognostic (7.73e-2)" "unprognostic (1.85e-1)" "unprognostic (1.02e-2)" "unprognostic (5.95e-2)" "unprognostic (4.24e-2)" "unprognostic (7.07e-2)" "unprognostic (1.17e-1)" "unprognostic (3.82e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (2.02e-1)" "unprognostic (1.03e-2)" "unprognostic (1.87e-1)" "unprognostic (1.25e-3)" 57.3 31.1 14.4 69.3 30.0 69.7 51.6 19.8 20.5 62.0 26.9 67.1 32.3 72.2 21.3 75.6 45.1 55.0 22.9 17.0 21.5 35.6 18.8 74.2 58.9 29.0 24.6 39.6 30.1 49.7 12.1 79.8 28.1 36.2 66.9 7.1 72.2 38.0 15.0 64.9 37.9 81.3 16.5 57.7 52.6 13.0 27.9 65.4 64.3 25.4 63.4 63.5 31.4 63.4 148.9 81.5 39.8 46.6 99.3 128.4 229.6 139.7 127.0 124.7 132.4 93.6 150.5 82.7 66.2 231.5 111.4 259.2 80.6 153.5 149.5 106.4 56.6 55.5 145.8 34.3 120.2 102.9 113.6 76.2 139.5 147.2 206.5 152.7 172.8 53.0 49.0 112.8 192.3 76.5 55.4 30.8 51.6 235.8 45.6 67.5 106.5 72.1 126.9 233.8 49.5 37.3 195.1 96.9 100.7 162.8 85.1 86.5 224.2 141.1 73.4 120.4 145.6 43.3 67.0 82.4 128.3 98.5 77.5 30.6 27.5 20.0 21.8 25.2 19.3 12.6 13.5 18.9 23.3 12.5 7.9 14.0 89.9 27.6 31.0 13.8 16.1 16.9 14.4 30.0 19.8 20.5 17.0 21.5 29.0 24.6 28.1 16.5 27.9 63.4 180.9 266.0 286.3 36.2 129.2 103.0 124.9 87.7 72.8 4.6 115.1 88.4 18.0 54.3 167.2 77.3 16.7 89.7 215.3 204.5 7.9 95.9 8.8 133.8 127.9 135.7 60.7 46.7 39.7 98.7 159.4 116.5 91.7 242.0 209.3 130.2 95.3 11.6 149.0 1.7 24.4 121.1 63.1 407.5 175.1 13.2 47.8 261.6 71.2 60.9 272.2 13.5 200.8 9.5 316.0 128.1 112.1 48.2 137.3 98.6 72.7 19.6 134.2 30.2 78.9 108.8 131.0 18.9 32.6 99.3 113.4 95.6 176.8 56.0 152.0 151.5 IRS1 HIRS-1 ENSG00000169047 "Insulin receptor substrate 1" P35568 2 226731312-226799820 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 75.4;Theca cells: 110.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005261, HPA046433" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005261: AB_649615, HPA046433: AB_2732524" "unprognostic (2.20e-1)" "unprognostic (1.98e-2)" "unprognostic (2.52e-1)" "unprognostic (1.59e-2)" "unprognostic (3.86e-3)" "unprognostic (1.61e-1)" "unprognostic (1.44e-1)" "unprognostic (1.80e-3)" "unprognostic (5.47e-2)" "unprognostic (2.24e-2)" "unprognostic (5.48e-3)" "unprognostic (1.10e-1)" "unprognostic (1.36e-3)" "unprognostic (1.46e-2)" "unprognostic (6.92e-2)" "unprognostic (3.23e-2)" "unprognostic (7.55e-3)" 7.6 9.7 1.7 2.9 1.6 0.5 11.7 5.2 3.1 14.7 1.8 10.3 3.9 17.4 1.9 3.6 15.0 5.6 5.0 1.6 1.0 3.4 10.5 5.0 1.7 1.8 1.6 20.9 3.5 3.3 1.5 9.5 1.2 7.8 2.7 1.5 3.0 7.0 28.0 5.2 5.1 10.3 2.0 2.0 5.3 0.8 1.6 8.1 20.0 2.9 1.3 11.6 6.6 1.5 5.7 26.0 18.6 0.7 25.0 14.8 0.0 15.6 12.2 20.4 13.0 15.0 14.4 2.3 2.5 10.6 14.0 10.0 1.2 15.0 11.5 5.9 1.0 0.1 1.7 7.1 12.5 0.5 0.1 20.7 8.1 16.1 14.5 12.3 0.0 2.3 3.0 22.7 14.0 22.6 4.9 6.6 7.5 3.6 14.3 1.1 24.1 0.1 9.3 18.9 3.2 0.5 5.0 3.6 8.4 14.9 13.7 0.3 1.3 26.8 24.2 20.9 15.1 10.6 4.6 3.4 26.5 0.5 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.6 5.2 3.1 1.6 1.0 1.8 1.6 1.2 2.0 1.6 1.5 1.7 19.2 4.6 5.9 2.7 35.4 31.9 29.7 19.4 19.3 36.9 28.1 13.4 14.3 12.8 0.0 0.0 6.4 0.0 13.2 17.6 15.4 1.6 22.1 28.4 2.1 2.4 0.0 17.3 11.4 0.6 28.3 2.0 24.3 0.0 75.4 1.8 57.4 1.7 20.2 31.3 6.5 24.4 1.3 4.6 1.8 22.7 3.6 16.0 15.0 0.8 8.4 0.0 26.7 1.7 11.1 8.2 14.7 9.5 14.5 23.4 3.0 8.1 1.7 13.1 9.5 22.8 1.0 1.2 4.2 23.7 18.3 1.2 110.3 7.7 22.8 ITGA3 "CD49c, GAP-B3, MSK18, VCA-2, VLA3a" ENSG00000005884 "Integrin subunit alpha 3" P26006 17 50055968-50090481 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 111.9;Exocrine glandular cells: 105.1;Pancreatic endocrine cells: 245.6;Urothelial cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 647.2;hTERT-RPE1: 572.8;RPTEC TERT1: 562.0;U-87 MG: 920.8;WM-115: 570.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008572, CAB018594" Enhanced Supported "Plasma membrane" NA NA 170000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "CAB018594: AB_668044, HPA008572: AB_2668094" "unprognostic (3.24e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (9.51e-2)" "unprognostic (3.46e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (8.28e-3)" "unprognostic (2.76e-3)" "unprognostic (1.26e-3)" "unprognostic (1.82e-2)" "prognostic unfavorable (5.95e-5)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (2.35e-2)" 17.5 29.8 5.3 9.9 5.4 0.4 17.3 6.0 6.1 14.8 5.2 25.4 30.4 21.3 11.7 24.1 24.5 17.9 13.2 5.0 10.9 68.9 2.2 65.8 3.0 7.5 6.6 12.8 15.9 17.7 21.1 26.7 11.9 19.5 15.5 4.4 19.4 15.7 9.0 30.8 26.7 15.6 4.2 11.1 24.5 2.1 7.8 5.9 43.5 4.1 6.2 46.7 17.1 4.0 181.8 234.9 1.4 7.5 4.3 17.5 37.3 83.4 177.9 123.1 93.2 5.3 276.2 0.4 507.9 59.5 400.4 126.8 2.2 647.2 73.9 22.9 3.5 0.1 56.8 1.6 105.1 0.3 5.0 21.6 313.5 123.2 540.7 572.8 91.6 9.1 0.1 2.6 236.0 52.9 0.7 0.5 5.5 81.2 141.0 0.4 12.1 13.7 562.0 311.1 9.7 3.9 89.8 12.2 205.0 56.2 21.1 2.4 200.8 541.8 169.4 5.6 329.5 8.1 14.2 5.9 920.8 1.9 570.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 5.4 6.0 6.1 5.0 10.9 7.5 6.6 11.9 4.2 7.8 4.0 8.5 54.5 30.1 3.6 3.4 57.4 63.5 63.5 48.3 18.0 17.1 32.0 5.3 27.1 26.2 77.3 25.0 2.8 1.3 91.2 0.0 111.9 0.5 26.4 3.1 14.7 14.5 0.0 24.3 105.1 3.2 5.3 47.4 20.7 3.8 3.4 8.9 0.3 1.1 3.3 20.0 25.1 16.2 1.2 8.2 0.6 1.8 2.0 17.8 8.4 4.3 3.1 2.1 3.0 0.8 245.6 26.7 4.1 4.5 72.6 69.6 4.4 21.7 16.2 13.1 5.6 23.4 0.5 1.6 17.0 23.2 1.8 3.8 0.9 44.7 104.2 ITGB1 "CD29, FNRB, GPIIA, MDF2, MSK12" ENSG00000150093 "Integrin subunit beta 1" P05556 10 32887273-33005792 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1206.9;Pancreatic endocrine cells: 1393.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 2711.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003434, HPA059297, HPA069003" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Focal adhesion sites" NA NA 270000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Focal adhesion sites" "Endoplasmic reticulum" "CAB003434: AB_303570, HPA059297: AB_2732634, HPA069003: AB_2732125" "unprognostic (3.07e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.67e-2)" "unprognostic (4.36e-1)" "unprognostic (1.20e-2)" "unprognostic (3.87e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.22e-1)" "unprognostic (2.36e-3)" "unprognostic (3.68e-3)" "unprognostic (2.42e-1)" "unprognostic (1.02e-3)" "unprognostic (1.25e-2)" "unprognostic (2.23e-1)" "unprognostic (2.48e-1)" "unprognostic (3.08e-2)" 491.9 179.3 61.5 241.5 78.2 81.5 216.2 75.0 90.9 259.2 68.3 265.3 147.4 330.4 171.7 168.6 172.0 347.4 390.3 60.2 74.3 180.4 287.1 233.6 118.0 88.4 80.6 157.1 135.3 145.4 59.8 459.5 88.9 248.1 223.6 27.7 130.7 427.7 157.9 92.2 150.8 710.0 76.6 204.7 160.1 91.2 86.4 77.5 161.5 194.5 106.2 357.4 119.1 88.9 638.0 907.0 495.4 559.6 1183.4 1019.5 398.1 2063.9 1239.6 999.0 903.9 215.9 1478.2 164.5 354.1 1830.9 638.0 438.9 149.1 1204.1 1122.0 163.1 112.7 195.8 416.3 253.6 826.4 48.3 195.5 1027.7 658.2 1040.8 426.0 2711.1 1263.6 81.0 136.6 76.5 1700.8 109.0 80.1 46.7 107.4 200.6 428.2 52.0 357.0 30.9 1454.8 186.2 108.0 271.4 649.9 114.6 498.2 813.7 153.9 175.0 1362.6 1280.0 712.2 904.2 719.7 64.7 14.8 91.2 956.6 198.2 518.5 7.5 35.1 16.1 83.4 69.8 22.8 109.6 191.8 138.7 33.9 40.3 24.9 68.4 9.0 90.3 108.2 11.4 266.8 117.2 61.5 78.2 75.0 90.9 60.2 74.3 88.4 80.6 88.9 76.6 86.4 88.9 631.5 342.9 143.8 26.4 118.0 546.7 435.5 531.6 208.3 32.8 147.1 307.5 210.8 241.6 268.1 226.2 31.3 210.3 217.8 179.8 13.7 1206.9 6.6 194.6 437.9 421.1 193.3 153.0 37.2 411.3 515.2 374.7 95.8 406.5 88.7 561.8 375.9 268.1 179.8 38.7 52.4 97.4 213.6 170.1 206.7 18.3 254.5 217.8 343.3 67.5 119.4 72.0 111.2 42.7 66.8 1393.7 128.5 601.8 181.2 412.5 75.6 68.7 171.5 45.5 637.7 236.3 724.0 10.1 76.0 84.4 170.5 219.7 211.3 225.6 127.0 296.1 ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 376.2;lymphoid tissue: 175.2" "Group enriched" "Detected in many" 6 "dendritic cells: 417.6;Hofbauer cells: 652.4;Kupffer cells: 485.9;Langerhans cells: 259.1;Macrophages: 527.4;monocytes: 463.8;NK-cells: 959.9;T-cells: 254.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "THP-1: 812.4;U-937: 615.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" 54.5 23.2 8.2 175.2 9.5 376.2 15.4 13.1 9.3 15.5 11.7 25.2 23.8 8.5 2.8 16.2 17.0 36.4 11.8 7.7 14.2 8.4 23.4 78.0 169.1 29.5 19.9 7.2 11.3 5.1 4.6 44.4 28.1 8.8 13.9 1.1 19.5 9.2 6.8 9.3 32.8 46.4 23.9 137.2 29.1 5.9 26.2 87.2 7.3 7.6 68.4 46.3 5.9 50.4 1.9 4.8 0.0 0.0 0.0 0.3 1.7 0.0 2.7 0.1 0.0 0.4 0.4 17.9 128.1 0.2 0.6 0.5 0.0 0.2 0.0 1.5 1.4 18.2 0.0 3.2 0.1 106.6 27.5 1.6 0.1 0.5 0.3 0.1 0.3 58.0 0.7 1.4 7.0 4.0 117.8 126.1 0.4 0.4 2.4 1.5 23.2 64.6 4.7 0.0 0.6 1.3 3.4 2.5 1.7 0.0 0.4 812.4 2.5 0.2 6.6 0.4 3.7 0.8 5.9 2.9 0.1 615.0 0.9 186.6 1848.8 1224.1 726.7 1144.9 326.6 86.1 349.7 506.5 1031.4 115.2 233.1 396.5 1386.1 585.5 1183.5 165.5 288.0 3034.2 8.2 9.5 13.1 9.3 7.7 14.2 29.5 19.9 28.1 23.9 26.2 50.4 7.1 16.0 29.6 0.3 81.7 5.5 0.5 9.6 0.6 0.0 4.1 6.5 4.0 14.3 18.6 5.5 0.0 4.0 417.6 0.3 0.0 3.4 1.0 0.6 0.5 16.8 0.0 19.6 0.5 0.4 4.8 5.3 2.6 0.7 24.1 8.2 9.7 8.6 652.4 0.0 0.3 0.2 2.0 485.9 259.1 2.8 0.6 527.4 5.4 27.2 463.8 0.4 959.9 0.0 0.2 0.6 0.1 1.5 50.5 0.6 1.8 4.2 3.6 0.8 6.6 2.1 3.2 0.2 1.0 0.9 5.1 5.6 254.5 0.0 0.3 0.7 ITGB3 "CD61, GP3A, GPIIIa" ENSG00000259207 "Integrin subunit beta 3" P05106 17 47253827-47313743 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 51.4" "Cell type enhanced" "Detected in some" "Early spermatids: 3.9;Late spermatids: 8.8;Macrophages: 15.8;Proximal tubular cells: 4.6;Sertoli cells: 6.6" "Group enriched" "Detected in many" 6 "melanoma: 7.5;renal cancer: 3.6;thyroid cancer: 11.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 19 "basophil: 5.4;neutrophil: 2.5" "Lineage enriched" "Detected in single" 26 "granulocytes: 5.4" "Cell line enhanced" "Detected in many" "EFO-21: 167.8;HEL: 163.4;RPTEC TERT1: 109.8;U-87 MG: 78.3;WM-115: 255.9" HPA027852 Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 38000000 "Cluster 34: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" Nucleoplasm "HPA027852: AB_10601760" "unprognostic (1.13e-2)" "unprognostic (1.97e-3)" "unprognostic (2.47e-1)" "unprognostic (3.00e-2)" "unprognostic (1.91e-2)" "unprognostic (6.04e-3)" "unprognostic (3.70e-1)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.85e-1)" "unprognostic (6.35e-2)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.03e-2)" "unprognostic (2.72e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-3)" 8.0 0.6 0.3 9.5 0.7 6.2 5.3 0.7 1.0 3.8 1.0 16.9 3.5 13.2 2.6 4.2 7.6 3.5 5.5 0.5 0.8 15.0 3.4 5.6 0.9 2.3 1.0 1.5 0.7 1.2 1.2 4.5 2.0 4.8 7.0 0.9 2.6 16.1 1.5 2.7 5.8 22.9 1.2 2.9 3.8 2.5 1.2 0.3 51.4 2.4 1.2 9.6 2.6 1.1 0.1 1.5 0.7 0.1 8.6 3.8 0.1 4.7 23.1 9.6 8.6 0.3 0.1 0.6 167.8 1.2 13.4 0.0 0.1 0.0 12.6 3.4 0.0 163.4 0.5 0.0 7.8 0.0 0.2 3.4 0.0 54.6 1.4 6.7 43.6 2.5 0.5 0.3 2.1 0.0 1.0 0.1 0.1 0.0 0.8 0.0 4.2 0.0 109.8 0.2 0.0 0.5 5.6 0.0 33.2 8.8 0.1 0.2 47.1 2.1 2.4 1.3 11.7 0.2 0.1 1.1 78.3 0.0 255.9 5.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.1 0.1 0.1 0.0 6.8 0.3 0.7 0.7 1.0 0.5 0.8 2.3 1.0 2.0 1.2 1.2 1.1 1.3 0.0 0.0 0.0 0.5 0.1 0.2 0.9 0.0 0.0 0.1 0.3 0.8 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 3.9 0.8 0.9 3.1 0.0 0.0 0.4 0.4 0.0 2.1 0.0 0.9 0.0 0.6 1.8 0.7 0.8 0.0 0.6 0.0 0.0 0.3 0.7 8.8 0.3 15.8 0.0 1.0 0.4 0.0 0.0 0.0 0.4 1.5 0.0 1.2 0.0 0.3 0.0 4.6 0.2 0.0 6.6 0.3 2.1 0.0 2.0 0.1 0.4 1.2 0.3 0.4 0.0 0.2 ITGB4 CD104 ENSG00000132470 "Integrin subunit beta 4" P16144 17 75721328-75757818 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 200.6;skin 1: 205.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 173.6;Distal enterocytes: 133.3;Gastric mucus-secreting cells: 165.1;Pancreatic endocrine cells: 284.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 897.3;HaCaT: 345.1;HBEC3-KT: 768.6;hTCEpi: 256.9;RT4: 254.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 37.4" "CAB002422, CAB005258, HPA036348, HPA036349" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 980000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cell Junctions" "CAB002422: AB_563480, CAB005258: AB_2129021, HPA036348: AB_2675077, HPA036349: AB_2675078" "unprognostic (3.17e-3)" "unprognostic (3.52e-1)" "unprognostic (4.19e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (6.11e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.18e-4)" "unprognostic (1.05e-1)" "unprognostic (4.14e-2)" "prognostic unfavorable (6.39e-4)" "unprognostic (1.02e-1)" "unprognostic (2.23e-2)" "unprognostic (1.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" 39.2 5.3 82.8 12.4 87.8 1.6 66.6 74.9 91.8 58.4 76.4 87.5 56.9 24.0 3.6 101.2 43.8 20.0 22.7 80.5 86.9 18.2 5.6 18.4 4.5 104.6 104.8 8.5 24.5 2.8 21.1 35.4 82.6 85.3 15.7 8.7 200.6 18.5 6.8 205.9 75.5 6.4 102.4 76.9 79.9 4.9 82.0 4.1 17.6 6.0 7.2 58.4 98.8 99.6 172.7 148.5 0.3 2.1 0.4 1.3 199.2 0.7 0.6 0.5 0.9 16.1 897.3 0.1 31.5 0.3 1.3 345.1 1.0 768.6 0.5 0.7 0.6 0.9 39.6 17.0 1.2 0.2 1.8 1.1 256.9 0.6 159.2 18.0 5.5 0.6 0.5 15.7 0.1 95.8 2.0 2.0 1.0 92.8 127.8 2.7 4.4 2.2 204.8 254.9 0.2 1.9 4.9 15.2 2.2 5.3 63.9 1.5 16.9 4.6 7.8 0.7 1.9 5.6 2.1 0.7 2.0 0.8 2.7 0.0 0.2 0.0 0.4 0.4 1.1 0.7 0.1 0.5 0.0 2.0 0.4 0.3 0.7 0.0 0.0 4.6 0.8 0.4 82.8 87.8 74.9 91.8 80.5 86.9 104.6 104.8 82.6 102.4 82.0 99.6 26.9 12.8 2.2 50.3 1.4 49.5 45.1 173.6 67.2 0.3 21.2 36.6 7.5 25.8 38.9 23.9 2.1 89.8 1.8 133.3 1.9 33.3 0.4 61.3 5.7 26.8 9.6 0.8 0.7 28.8 20.2 5.2 165.1 60.2 2.5 1.1 17.9 0.4 9.4 0.0 0.7 59.2 18.3 0.3 5.4 0.4 3.7 1.9 12.4 1.9 0.1 34.4 0.0 1.5 0.7 284.4 68.4 1.5 2.6 17.1 94.0 2.6 53.3 1.0 0.0 1.2 5.0 1.1 8.2 28.1 13.1 111.1 1.8 0.5 60.1 42.0 ITSN1 "ITSN, MGC134948, MGC134949, SH3D1A, SH3P17" ENSG00000205726 "Intersectin 1" Q15811 21 33642400-33899861 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Exocytosis, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 217.4;Inhibitory neurons: 151.9;Rod photoreceptor cells: 146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 5.5;non-classical monocyte: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 115.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018007 Approved Supported "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA018007: AB_1851836" "unprognostic (2.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.62e-1)" "unprognostic (1.21e-1)" "unprognostic (3.91e-1)" "unprognostic (1.81e-1)" "unprognostic (1.10e-1)" "unprognostic (3.94e-2)" "unprognostic (7.33e-3)" "unprognostic (1.31e-2)" "unprognostic (3.23e-1)" "unprognostic (3.25e-2)" "unprognostic (1.16e-2)" "unprognostic (6.78e-3)" "unprognostic (2.37e-1)" "unprognostic (6.02e-2)" "unprognostic (5.64e-2)" 55.5 15.5 18.0 9.9 18.4 6.8 27.9 16.4 26.2 19.8 22.8 14.7 8.9 20.3 12.0 11.4 16.7 19.8 20.9 18.3 14.0 10.9 26.4 11.5 6.8 14.5 13.6 19.6 5.0 7.0 6.7 24.4 14.9 14.5 11.0 28.5 7.9 22.3 22.0 11.9 9.7 18.4 8.8 15.4 11.1 12.3 17.0 5.0 10.3 22.0 3.9 15.4 13.4 14.1 36.3 14.9 70.4 23.4 32.3 30.8 115.3 35.8 34.4 20.6 19.8 56.7 27.0 8.5 28.3 43.1 42.7 13.7 42.2 24.9 22.0 3.5 18.6 10.3 30.9 26.7 24.4 7.4 9.9 30.5 22.0 38.6 21.2 23.5 55.3 9.8 13.7 5.8 33.4 8.2 10.3 9.8 104.5 12.6 11.3 13.2 33.7 17.6 30.9 14.7 13.2 14.4 51.4 10.6 12.6 44.6 13.0 7.2 50.2 22.9 30.9 18.1 12.5 7.0 20.8 7.9 20.8 22.9 26.0 0.0 4.2 5.5 0.3 3.2 0.3 0.0 0.5 0.1 1.3 0.0 0.2 0.1 0.2 0.1 5.1 0.3 0.0 0.8 18.0 18.4 16.4 26.2 18.3 14.0 14.5 13.6 14.9 8.8 17.0 14.1 19.8 25.6 18.6 217.4 1.8 18.1 22.6 10.8 36.5 73.1 12.2 8.1 81.8 18.6 14.5 11.0 91.8 20.8 1.1 22.4 0.0 19.9 10.2 13.3 67.7 21.3 9.1 47.4 110.9 12.5 28.0 31.9 19.4 21.0 2.5 30.7 28.2 54.2 55.6 65.6 151.9 7.2 20.3 30.0 10.9 8.6 24.8 27.3 10.6 74.0 10.8 46.9 0.0 80.4 46.4 37.1 10.3 71.5 3.1 18.3 16.8 16.6 18.8 146.2 13.1 20.1 39.7 32.4 47.7 8.9 11.8 15.6 2.7 21.4 10.5 27.2 IYD "C6orf71, DEHAL1, dJ422F24.1" ENSG00000009765 "Iodotyrosine deiodinase" Q6PHW0 6 150368892-150405969 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 472.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 23.7;Hepatocytes: 25.1;Intestinal goblet cells: 21.8;Paneth cells: 22.5;Proximal enterocytes: 89.1;Proximal tubular cells: 35.4" "Cancer enriched" "Detected in many" 20 "thyroid cancer: 80.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CACO-2: 1.3;OE19: 3.0;SK-BR-3: 3.2" "Group enriched" "Detected in some" 13 "hippocampal formation: 7.4;thalamus: 2.4" "Low region specificity" "Detected in all" HPA059627 Enhanced Supported "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 1: Thyroid gland - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA059627: AB_2684086" "unprognostic (3.73e-4)" "unprognostic (2.93e-2)" "unprognostic (5.97e-2)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (2.98e-2)" "prognostic favorable (6.22e-4)" "unprognostic (1.11e-1)" "unprognostic (3.80e-2)" "unprognostic (1.17e-1)" "unprognostic (7.41e-2)" "unprognostic (1.02e-1)" "unprognostic (3.07e-9)" "unprognostic (9.79e-3)" "unprognostic (2.04e-1)" "unprognostic (2.03e-2)" "unprognostic (2.18e-2)" 0.1 0.0 0.4 0.6 0.3 0.3 0.5 0.6 0.6 0.1 0.2 6.4 18.1 0.2 0.6 0.0 0.0 8.9 0.5 0.3 0.1 26.6 33.6 0.7 0.5 0.5 0.4 0.0 0.4 0.0 0.0 0.0 0.6 0.2 6.5 0.2 0.1 0.0 0.0 0.2 19.6 0.2 0.0 0.1 2.0 0.2 0.5 0.0 472.7 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 3.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 3.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 1.6 0.5 0.3 0.2 0.4 0.2 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.9 0.7 0.2 0.3 0.2 1.3 0.4 0.3 0.6 0.6 0.3 0.1 0.5 0.4 0.6 0.0 0.5 0.5 0.7 3.2 7.8 0.0 0.0 0.1 0.6 0.2 0.0 0.1 0.3 0.4 0.8 14.3 8.9 0.0 0.0 0.1 0.0 23.7 1.9 0.3 0.0 0.9 0.3 0.4 3.6 2.7 0.1 0.2 0.0 0.7 0.0 2.2 1.3 0.1 1.1 25.1 0.1 0.0 0.1 21.8 0.0 0.0 1.2 0.1 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 22.5 0.0 0.0 1.0 89.1 35.4 3.6 1.3 0.0 1.7 0.3 0.1 0.1 0.0 0.4 0.3 0.9 0.4 11.5 0.7 JAM2 "C21orf43, CD322, JAM-B, JAMB, VE-JAM" ENSG00000154721 "Junctional adhesion molecule 2" P57087 21 25639258-25717562 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 63.5" "Cell type enhanced" "Detected in many" "Adipocytes: 173.8;Astrocytes: 81.6;Endothelial cells: 148.7;Hepatic stellate cells: 112.8;Microglial cells: 82.4;Oligodendrocyte precursor cells: 76.9" "Cancer enriched" "Detected in all" 9 "glioma: 27.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.5;BJ hTERT+: 16.5;HDLM-2: 16.7;hTERT-RPE1: 22.5;U-138 MG: 18.1;U-87 MG: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028789, HPA077346" Supported "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "HPA028789: AB_2732443, HPA077346: AB_2732341" "unprognostic (1.42e-1)" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (2.02e-2)" "unprognostic (1.53e-2)" "unprognostic (7.51e-4)" "unprognostic (2.61e-2)" "unprognostic (4.55e-1)" "unprognostic (1.02e-1)" "unprognostic (3.46e-2)" "unprognostic (3.81e-1)" "unprognostic (8.86e-2)" "unprognostic (5.71e-3)" "unprognostic (2.18e-1)" "unprognostic (2.20e-1)" "unprognostic (4.85e-3)" 20.5 15.8 16.6 3.7 21.5 0.3 16.8 24.0 21.8 16.8 12.8 17.8 6.1 18.5 11.2 7.1 16.1 12.9 19.2 19.2 22.0 9.2 2.2 15.5 3.6 25.9 23.1 16.1 2.8 4.3 8.1 63.5 21.3 9.4 7.9 7.1 6.1 15.4 7.8 5.5 10.7 19.6 26.8 1.6 10.2 17.6 25.2 2.6 10.3 13.2 5.0 11.6 13.2 23.0 0.0 0.0 25.5 0.1 1.0 0.2 0.5 0.8 16.5 2.0 7.6 0.0 0.0 0.1 0.0 0.2 9.7 0.1 2.2 0.0 4.6 16.7 0.7 0.1 0.1 0.1 0.0 0.1 0.1 1.4 0.0 1.8 0.1 22.5 0.0 0.6 0.0 0.2 8.0 0.0 0.4 0.1 8.1 0.2 0.0 3.2 5.3 0.1 0.0 0.0 0.4 3.7 0.2 0.3 0.0 0.3 0.9 0.2 0.0 18.1 1.7 0.1 2.5 1.8 0.1 0.0 13.4 0.1 0.7 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.6 0.1 0.2 0.4 0.6 0.1 0.4 0.0 0.1 16.6 21.5 24.0 21.8 19.2 22.0 25.9 23.1 21.3 26.8 25.2 23.0 173.8 0.0 2.3 81.6 0.9 7.5 1.4 0.0 2.2 1.4 1.4 9.1 33.2 0.0 0.0 3.7 14.6 0.3 0.5 0.0 0.0 0.2 16.5 1.0 4.7 148.7 0.0 0.0 15.2 0.2 5.3 28.5 0.5 2.1 0.0 4.5 112.8 0.5 1.3 0.0 45.0 0.0 0.0 1.8 10.7 15.6 9.9 2.8 16.0 82.4 0.0 1.8 0.0 76.9 4.1 0.1 0.0 24.5 1.2 1.5 0.0 0.0 0.7 5.2 0.0 5.7 7.0 6.7 4.4 0.8 6.7 0.8 1.6 2.1 0.0 1.2 JAML "AMICA, AMICA1, Gm638" ENSG00000160593 "Junction adhesion molecule like" Q86YT9 11 118193725-118225094 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.3;lymphoid tissue: 68.7" "Group enriched" "Detected in many" 4 "dendritic cells: 136.9;Kupffer cells: 125.8;Macrophages: 166.6;monocytes: 204.7;T-cells: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "eosinophil: 3529.6" "Group enriched" "Detected in all" 5 "dendritic cells: 1017.6;granulocytes: 3529.6;monocytes: 1023.8" "Cell line enriched" "Detected in some" 5 "HMC-1: 28.0" "Region enriched" "Detected in many" 11 "cerebellum: 58.0" "HPA005854, HPA047919" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Nucleoplasm "HPA005854: , HPA047919: AB_2680209" "unprognostic (3.91e-3)" "unprognostic (1.55e-3)" "unprognostic (3.00e-2)" "unprognostic (1.28e-3)" "unprognostic (2.87e-3)" "prognostic favorable (3.11e-4)" "unprognostic (2.80e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (8.69e-2)" "unprognostic (5.08e-1)" "unprognostic (6.43e-3)" "unprognostic (8.96e-2)" "unprognostic (3.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.58e-2)" 13.9 4.5 0.9 68.7 1.0 20.9 5.6 2.4 2.1 5.6 2.3 16.8 17.8 3.5 1.5 8.5 4.3 20.4 3.2 0.7 0.9 3.4 9.8 43.3 31.1 1.3 0.9 1.8 2.9 1.0 1.6 7.8 1.0 4.4 22.7 0.3 2.9 3.6 1.2 4.6 32.1 15.3 1.0 60.0 9.4 1.5 1.0 24.3 2.9 7.8 31.6 24.9 3.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.9 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 2.0 0.0 0.0 28.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.3 3.1 0.4 3.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.2 0.0 137.4 1023.8 3529.6 60.1 616.5 386.5 7.1 107.4 113.7 1017.6 2.9 124.7 103.1 2121.1 24.3 310.3 765.1 191.3 844.1 0.9 1.0 2.4 2.1 0.7 0.9 1.3 0.9 1.0 1.0 1.0 1.1 1.2 6.4 34.2 0.0 6.9 0.0 0.2 0.0 0.0 0.3 0.9 1.3 0.0 2.8 5.6 1.8 0.0 0.3 136.9 0.9 0.0 0.1 1.0 0.4 0.2 1.3 0.0 5.0 0.0 0.4 0.4 1.8 2.6 0.6 15.2 0.0 5.7 2.8 31.0 0.0 0.0 0.2 0.0 125.8 0.0 1.1 0.0 166.6 0.0 0.0 204.7 0.0 9.2 0.0 0.0 0.1 0.1 0.0 6.3 0.1 0.6 0.8 2.2 0.2 0.0 0.4 0.5 2.2 5.9 0.2 0.0 0.4 56.0 0.0 0.1 0.2 JUP "CTNNG, DP3, DPIII, PDGB, PKGB" ENSG00000173801 "Junction plakoglobin" P14923 17 41754604-41786931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes, Cardiomyopathy, Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 952.2;skin 1: 932.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 315.9;Pancreatic endocrine cells: 356.2;Squamous epithelial cells: 318.3;Suprabasal keratinocytes: 383.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.1;eosinophil: 28.7;intermediate monocyte: 22.6;memory B-cell: 13.5;myeloid DC: 14.5;naive B-cell: 11.7;non-classical monocyte: 43.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 1090.1;OE19: 3919.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002139, HPA032047" Supported Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 64000000 "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Vesicles "CAB002139: AB_563468, HPA032047: AB_2674124" "unprognostic (3.96e-3)" "unprognostic (3.40e-1)" "unprognostic (2.32e-1)" "unprognostic (4.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (8.11e-3)" "unprognostic (1.41e-2)" "unprognostic (9.85e-3)" "unprognostic (2.29e-3)" "unprognostic (9.60e-2)" "prognostic favorable (2.06e-10)" "unprognostic (2.50e-1)" "unprognostic (9.49e-2)" "unprognostic (9.05e-2)" "unprognostic (1.51e-2)" 46.5 16.0 13.6 23.6 21.6 20.7 68.6 20.8 18.9 243.7 25.8 94.9 88.1 57.0 15.3 952.2 69.9 39.8 145.1 14.6 14.3 120.7 70.9 57.1 15.7 20.7 16.2 46.2 59.6 19.9 37.3 51.5 19.6 68.0 49.0 4.7 226.4 41.8 110.8 932.4 95.7 23.1 14.8 22.7 86.3 12.5 16.2 29.6 86.4 62.2 92.0 68.7 432.6 33.6 268.8 217.8 21.7 18.5 0.2 0.1 330.6 15.3 89.2 5.9 5.2 332.6 289.0 5.4 157.8 9.7 7.5 1090.1 31.6 242.4 1.0 0.6 74.2 11.6 165.1 74.4 34.7 7.3 113.6 0.5 538.6 0.9 43.9 64.2 96.1 7.0 99.6 94.0 0.0 342.6 1.9 96.5 42.3 3919.9 36.2 313.5 0.2 202.5 165.8 674.0 52.2 38.6 33.8 652.1 1.9 98.6 545.9 8.0 152.4 0.3 14.8 6.8 5.1 8.2 31.2 5.5 1.5 12.7 2.6 3.9 13.1 28.7 0.0 22.6 0.0 13.5 0.0 0.2 14.5 11.7 0.2 0.1 0.6 0.8 43.8 4.5 0.1 5.7 13.6 21.6 20.8 18.9 14.6 14.3 20.7 16.2 19.6 14.8 16.2 33.6 56.9 60.9 36.8 4.6 10.6 196.9 218.5 104.5 100.2 1.9 87.3 77.0 87.8 48.6 80.9 132.4 4.2 98.9 1.1 315.9 27.4 212.2 28.5 112.6 21.1 55.2 66.8 3.4 0.5 135.4 167.3 25.6 136.1 247.0 11.4 16.5 41.4 34.1 14.4 0.0 1.6 125.0 81.4 7.7 32.7 8.3 5.0 10.9 12.4 2.8 6.3 18.2 0.0 7.1 13.6 356.2 223.7 0.0 3.9 220.1 141.1 35.6 45.7 4.3 6.6 37.4 18.8 2.5 4.5 318.3 383.3 185.7 6.1 3.2 129.2 301.6 KANK1 "ANKRD15, KANK, KIAA0172" ENSG00000107104 "KN motif and ankyrin repeat domains 1" Q14678 9 470291-746106 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 355.5;Late spermatids: 228.7;Oligodendrocyte precursor cells: 322.7;Oligodendrocytes: 191.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.0" "Group enriched" "Detected in many" 15 "B-cells: 1.1;dendritic cells: 4.0;T-cells: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 96.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005539, HPA056090" Approved Supported "Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "HPA005539: AB_1078164, HPA056090: AB_2683034" "unprognostic (6.59e-2)" "unprognostic (3.33e-2)" "unprognostic (1.06e-3)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" "unprognostic (7.53e-2)" "unprognostic (3.33e-1)" "unprognostic (1.23e-2)" "unprognostic (4.91e-2)" "unprognostic (3.05e-2)" "unprognostic (2.84e-2)" "unprognostic (1.24e-1)" "unprognostic (3.07e-2)" "unprognostic (2.72e-1)" "unprognostic (3.06e-2)" "unprognostic (1.82e-1)" "unprognostic (1.61e-1)" 42.6 9.6 49.0 9.5 52.7 1.5 31.2 42.3 47.5 40.9 61.8 49.2 12.1 62.2 13.0 64.6 31.7 15.2 88.2 45.1 44.9 31.6 101.9 13.6 7.6 51.6 44.9 22.1 28.3 9.4 27.9 25.8 48.3 42.5 14.9 11.0 29.9 31.8 66.4 51.8 23.6 37.4 47.6 6.9 25.9 15.4 48.4 9.4 30.8 39.9 11.8 70.1 52.3 48.9 5.9 12.2 4.0 72.0 57.8 21.9 19.9 37.1 25.8 3.1 3.7 30.2 2.5 46.2 8.9 46.0 7.0 12.3 15.7 30.4 5.3 22.7 8.3 0.1 17.0 96.0 8.1 11.2 0.0 12.6 41.6 3.2 35.6 13.2 31.2 1.6 2.4 56.4 23.1 14.4 4.5 46.9 5.3 8.9 9.0 1.7 7.9 8.6 24.5 36.1 1.8 0.0 3.6 10.9 50.9 33.3 7.1 8.7 46.1 8.4 3.2 10.8 17.1 9.8 61.9 0.2 5.6 21.1 15.8 0.0 0.1 0.0 0.1 0.1 0.0 0.8 1.3 0.4 0.4 1.1 2.4 0.8 0.0 0.1 0.0 4.0 1.7 0.5 49.0 52.7 42.3 47.5 45.1 44.9 51.6 44.9 48.3 47.6 48.4 48.9 18.3 12.8 34.2 355.5 4.9 23.1 102.1 11.4 37.0 22.2 16.8 18.0 94.1 24.3 8.1 18.4 41.7 89.2 15.7 8.3 7.9 11.6 102.3 14.2 15.4 21.9 18.0 9.1 12.1 7.9 6.8 21.8 7.7 13.1 1.3 38.5 23.6 70.0 13.3 0.0 29.0 12.8 4.1 6.9 6.5 228.7 32.3 3.3 23.2 60.9 1.2 6.5 0.0 322.7 191.4 9.6 7.5 20.7 10.7 50.5 17.6 13.6 7.0 20.2 26.3 129.9 24.0 28.4 25.6 36.2 25.7 66.2 4.7 6.9 26.0 63.6 KANSL2 "C12orf41, FLJ20436, NSL2" ENSG00000139620 "KAT8 regulatory NSL complex subunit 2" Q9H9L4 12 48653211-48682238 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038497, HPA038498" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Plasma membrane, Cytosol" "HPA038497: AB_10674685, HPA038498: AB_2676046" "unprognostic (3.87e-3)" "unprognostic (6.18e-2)" "unprognostic (3.67e-1)" "unprognostic (8.89e-2)" "unprognostic (5.37e-2)" "unprognostic (4.73e-2)" "prognostic unfavorable (4.98e-4)" "unprognostic (5.46e-2)" "unprognostic (1.35e-3)" "unprognostic (6.16e-2)" "unprognostic (6.75e-3)" "unprognostic (4.19e-3)" "unprognostic (8.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "prognostic favorable (4.32e-4)" 11.9 11.4 6.0 8.2 7.0 41.8 12.2 8.6 8.0 13.9 7.3 11.8 8.1 14.1 11.5 13.3 12.6 7.7 13.4 6.5 6.9 12.2 9.8 10.9 13.9 7.0 6.5 16.3 9.7 12.2 9.3 12.2 6.7 11.1 9.3 11.8 13.0 8.3 40.7 13.4 11.9 9.8 6.7 13.2 10.8 14.6 6.8 14.2 11.5 23.1 13.8 12.4 12.8 8.8 19.5 26.5 21.8 12.8 25.6 22.0 48.1 20.8 17.6 35.9 19.5 45.2 25.1 31.9 39.0 25.5 14.0 18.3 37.1 23.5 29.5 30.4 22.5 37.1 20.2 12.9 29.2 40.0 13.9 20.8 31.2 25.5 46.2 18.0 17.2 24.8 43.7 20.9 25.0 18.7 39.2 29.2 28.6 28.1 26.0 33.4 21.3 35.9 17.2 27.1 25.1 17.6 43.2 30.0 25.7 21.8 40.2 43.4 12.8 25.5 18.9 10.9 19.7 29.8 50.7 46.2 12.4 89.5 13.6 35.3 19.7 23.5 25.1 21.2 23.7 27.3 23.9 25.9 25.8 23.8 27.9 26.9 9.0 24.3 23.0 20.2 32.2 24.0 6.0 7.0 8.6 8.0 6.5 6.9 7.0 6.5 6.7 6.7 6.8 8.8 18.0 3.2 14.3 9.8 24.7 11.9 14.7 17.9 32.5 15.6 15.7 15.5 10.9 8.6 15.0 14.7 29.2 22.5 36.5 10.2 9.8 13.3 24.4 8.2 13.9 13.7 9.0 14.1 11.5 9.8 12.5 15.1 12.2 12.4 11.4 19.8 14.6 9.6 11.9 15.2 13.8 9.1 10.2 11.9 13.2 13.8 12.5 13.7 16.0 7.5 14.8 8.2 11.3 15.1 18.8 12.2 4.7 10.1 16.9 12.1 10.8 15.6 10.2 22.8 26.3 15.7 16.6 38.5 34.8 19.9 11.2 25.3 30.6 15.9 12.4 9.8 KARS1 "DFNB89, KARS, KARS2" ENSG00000065427 "Lysyl-tRNA synthetase 1" Q15046 16 75627474-75648643 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Neurodegeneration, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 90.7;Cytotrophoblasts: 122.7;Extravillous trophoblasts: 143.3;Hofbauer cells: 89.5;Syncytiotrophoblasts: 110.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041345, HPA041550" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 82000 "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA041345: AB_10795589, HPA041550: AB_10794520" "unprognostic (1.56e-1)" "unprognostic (7.93e-2)" "unprognostic (3.36e-2)" "unprognostic (1.02e-2)" "unprognostic (5.39e-2)" "prognostic unfavorable (8.84e-6)" "unprognostic (6.24e-3)" "unprognostic (8.97e-3)" "unprognostic (1.18e-1)" "unprognostic (9.11e-3)" "unprognostic (8.71e-3)" "unprognostic (8.46e-2)" "unprognostic (7.86e-2)" "unprognostic (1.56e-1)" "unprognostic (1.03e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" 68.5 49.6 45.5 71.6 47.3 86.1 83.0 46.9 63.2 60.3 50.6 75.8 62.4 53.9 75.1 72.5 69.5 50.4 96.0 45.6 48.3 72.2 76.8 53.1 88.3 46.9 47.5 74.9 86.5 76.7 51.5 62.2 46.8 55.2 85.6 69.6 79.6 60.6 213.4 67.3 62.6 69.6 46.8 57.6 66.2 98.9 47.4 96.6 65.3 186.8 107.8 92.1 55.0 48.1 164.2 187.0 133.5 185.4 140.1 140.3 262.4 135.0 164.9 290.2 217.0 332.8 209.0 292.4 145.4 180.8 138.4 229.4 272.0 246.7 314.4 86.0 139.8 161.4 153.1 348.5 255.8 245.5 174.1 166.4 173.8 257.4 414.6 147.7 240.0 253.5 273.4 68.5 222.5 378.0 254.1 262.2 284.3 238.4 135.9 329.2 120.0 358.4 235.4 136.3 200.2 162.9 339.5 122.8 152.2 144.8 166.1 229.2 133.8 159.8 164.9 123.6 196.7 145.1 178.6 696.6 139.5 206.5 199.7 88.6 112.7 130.0 110.7 155.7 202.6 109.5 137.1 132.0 135.7 91.6 126.6 117.1 24.9 127.6 163.1 85.7 155.5 160.5 45.5 47.3 46.9 63.2 45.6 48.3 46.9 47.5 46.8 46.8 47.4 48.1 14.2 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.7 0.0 0.0 0.0 0.0 122.7 10.1 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 143.3 14.4 0.0 0.0 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 110.0 2.1 0.0 0.0 0.0 KCNAB1 "AKR6A3, hKvb3, hKvBeta3, KCNA1B, Kvb1.3" ENSG00000169282 "Potassium voltage-gated channel subfamily A member regulatory beta subunit 1" Q14722 3 156037701-156539138 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 52.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.8;Excitatory neurons: 108.6;Inhibitory neurons: 605.4;Oligodendrocyte precursor cells: 206.6;Oligodendrocytes: 97.5;Sertoli cells: 78.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HEL: 3.4;hTEC/SVTERT24-B: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036110, HPA044550" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "Nucleoplasm, Plasma membrane" "HPA036110: , HPA044550: AB_10797032" "unprognostic (1.52e-1)" "unprognostic (3.73e-1)" "unprognostic (1.33e-1)" "unprognostic (2.98e-4)" "unprognostic (1.24e-2)" "unprognostic (1.64e-1)" "unprognostic (1.81e-1)" "unprognostic (2.83e-2)" "unprognostic (8.51e-2)" "unprognostic (3.72e-2)" "unprognostic (5.87e-2)" "unprognostic (9.70e-2)" "unprognostic (2.17e-3)" "unprognostic (2.60e-1)" "unprognostic (1.95e-1)" "unprognostic (1.06e-1)" "unprognostic (4.00e-1)" 15.8 6.3 12.7 1.2 52.7 1.6 7.3 15.5 17.3 8.4 4.2 4.1 1.7 5.4 12.8 2.2 4.3 2.9 5.5 25.9 11.6 1.8 2.6 3.3 0.9 7.2 12.1 2.9 4.0 2.0 1.8 1.3 7.2 22.4 1.8 12.8 3.9 19.2 2.0 2.2 2.7 2.7 8.4 5.2 1.6 3.1 14.1 1.8 28.7 5.1 0.3 2.9 5.0 15.4 0.5 0.5 0.7 0.2 0.0 0.0 1.4 1.2 0.0 0.0 0.1 0.9 0.1 0.4 0.7 0.0 0.3 0.3 0.0 0.0 0.0 0.4 1.0 3.4 0.6 1.6 0.0 1.0 0.2 0.0 0.0 5.2 0.0 1.1 2.1 0.5 0.1 0.3 0.2 0.1 0.3 0.6 1.1 1.5 0.2 0.6 0.7 2.8 0.0 0.2 0.8 0.8 0.3 0.6 0.7 0.5 0.8 0.5 2.2 0.8 0.5 1.4 1.2 1.8 0.4 0.4 2.6 1.1 1.0 0.8 0.1 0.0 0.4 0.2 0.8 0.2 0.4 0.3 0.2 0.2 0.3 0.3 0.0 0.3 0.3 1.2 0.5 0.1 12.7 52.7 15.5 17.3 25.9 11.6 7.2 12.1 7.2 8.4 14.1 15.4 7.2 0.0 0.0 7.5 0.7 0.8 0.3 0.0 0.0 85.8 1.4 1.4 4.3 0.0 0.7 0.0 31.3 0.1 0.5 0.1 0.0 0.4 13.7 0.6 2.4 2.8 0.0 0.0 108.6 0.0 0.0 3.8 0.0 2.1 0.0 0.4 0.7 0.0 4.6 0.0 605.4 0.0 0.0 11.1 1.0 7.0 0.0 1.2 1.8 24.4 0.0 2.7 0.0 206.6 97.5 0.0 0.0 2.6 2.3 0.2 0.0 0.1 0.0 6.7 78.9 1.3 73.3 0.3 4.2 1.2 0.9 0.1 0.5 0.2 0.0 0.2 KCNE3 "HOKPP, MiRP2" ENSG00000175538 "Potassium voltage-gated channel subfamily E regulatory subunit 3" Q9Y6H6 11 74454841-74467729 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Brugada syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 70.5;stomach 1: 56.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 41.8;granulocytes: 33.7;Hofbauer cells: 40.6;Kupffer cells: 104.0;Macrophages: 37.8;monocytes: 59.0;Undifferentiated cells: 44.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 48 "basophil: 51.4;classical monocyte: 38.5;eosinophil: 23.4;intermediate monocyte: 41.8;myeloid DC: 18.3;neutrophil: 53.1;non-classical monocyte: 36.6" "Group enriched" "Detected in many" 115 "dendritic cells: 18.3;granulocytes: 53.1;monocytes: 41.8" "Cell line enhanced" "Detected in some" "HEL: 70.3;NB-4: 44.7;OE19: 155.3;THP-1: 32.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014849 Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA014849: AB_1852112" "unprognostic (1.61e-2)" "unprognostic (2.94e-1)" "unprognostic (1.11e-1)" "unprognostic (8.69e-2)" "unprognostic (3.58e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (4.67e-3)" "unprognostic (4.89e-4)" "unprognostic (4.12e-3)" "unprognostic (2.56e-2)" "unprognostic (2.97e-2)" "unprognostic (1.45e-3)" "unprognostic (7.86e-2)" "unprognostic (1.33e-2)" "unprognostic (1.73e-1)" "unprognostic (2.00e-1)" 7.3 2.8 2.8 20.7 2.9 8.2 5.2 2.5 3.6 9.9 7.0 34.9 70.5 8.8 1.9 4.6 9.4 24.6 5.0 3.0 3.0 20.1 5.0 13.8 5.0 3.8 3.6 14.0 10.8 3.6 3.1 12.7 3.6 8.0 47.3 8.1 15.4 3.4 1.3 1.3 40.0 11.1 3.3 12.6 56.2 1.8 4.1 1.9 33.5 3.0 3.2 6.2 4.5 4.9 0.1 0.1 0.1 0.2 8.1 2.1 7.1 0.1 0.0 1.0 0.8 23.0 2.0 0.3 21.3 0.1 0.1 0.3 1.8 0.0 0.7 0.0 0.2 70.3 0.4 4.7 2.9 0.6 12.0 7.1 0.0 0.6 0.0 0.3 0.3 0.1 1.9 0.3 0.8 0.1 0.1 44.7 0.9 155.3 0.1 7.6 0.3 0.5 1.7 0.0 0.0 0.4 0.1 0.0 0.0 5.4 0.1 32.7 0.1 0.1 0.2 0.2 0.1 0.3 0.3 0.4 0.1 12.9 0.1 51.4 38.5 23.4 0.1 41.8 0.2 0.2 0.1 0.1 18.3 0.3 0.1 0.1 53.1 0.2 36.6 0.7 0.0 13.2 2.8 2.9 2.5 3.6 3.0 3.0 3.8 3.6 3.6 3.3 4.1 4.9 4.4 0.0 6.8 0.3 0.7 0.3 0.6 1.1 3.4 0.2 0.2 0.3 0.7 8.6 5.6 1.8 0.0 0.4 0.0 8.6 3.9 0.5 0.1 3.1 3.4 8.9 2.4 2.1 0.2 7.3 7.4 4.5 41.8 5.0 33.7 0.2 5.7 2.0 40.6 0.0 0.3 27.9 4.1 104.0 2.9 0.3 3.7 37.8 0.0 8.4 59.0 22.7 1.0 0.0 0.0 3.3 8.9 2.6 0.2 0.4 8.6 23.4 4.6 1.2 0.0 4.7 0.7 0.0 0.4 2.7 0.1 2.1 1.0 8.8 44.3 0.6 KCNG4 Kv6.4 ENSG00000168418 "Potassium voltage-gated channel modifier subfamily G member 4" Q8TDN1 16 84218667-84239750 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 3.4;retina: 4.3" "Cell type enriched" "Detected in some" 14 "Bipolar cells: 56.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "cerebellum: 90.5;pons and medulla: 27.0" "Low region specificity" "Detected in many" HPA063516 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" Nucleoplasm "HPA063516: " "unprognostic (3.54e-1)" "unprognostic (6.67e-2)" 0.1 0.4 0.6 0.0 1.0 0.3 0.0 3.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.1 3.4 1.5 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 4.3 0.0 0.0 0.1 0.3 0.0 0.0 1.3 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.2 0.0 0.1 0.0 0.0 0.6 1.0 3.3 0.4 0.5 0.7 3.4 1.5 2.4 1.3 0.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 56.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 KCNH8 "elk3, Kv12.1" ENSG00000183960 "Potassium voltage-gated channel subfamily H member 8" Q96L42 3 19148510-19535642 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 16.0;pituitary gland: 10.7" "Group enriched" "Detected in some" 63 "Oligodendrocyte precursor cells: 331.7;Oligodendrocytes: 989.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.4" "Lineage enriched" "Detected in single" 4 "B-cells: 1.4" "Cell line enhanced" "Detected in some" "HAP1: 1.0;OE19: 1.9;SH-SY5Y: 4.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA016586, HPA077537, HPA077773" Approved Supported "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA016586: AB_1852127, HPA077537: , HPA077773: " "unprognostic (6.68e-3)" "unprognostic (1.68e-1)" "unprognostic (2.99e-2)" "unprognostic (8.56e-6)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.88e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (1.69e-1)" "unprognostic (5.04e-3)" "unprognostic (2.90e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (3.89e-2)" "unprognostic (8.71e-5)" "unprognostic (1.72e-1)" 0.0 1.8 7.3 0.3 11.9 0.2 0.5 6.5 16.0 0.3 2.8 0.6 0.4 0.1 0.1 0.1 0.2 0.4 0.2 6.4 8.8 0.1 0.1 0.0 0.8 8.4 8.8 0.0 1.5 0.1 10.7 0.0 8.2 0.7 0.5 3.4 1.1 0.2 0.0 0.4 1.1 0.1 5.8 1.1 1.4 1.7 9.7 0.4 0.2 0.0 0.7 0.1 0.3 15.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.3 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 7.3 11.9 6.5 16.0 6.4 8.8 8.4 8.8 8.2 5.8 9.7 15.4 0.0 0.0 0.0 2.0 9.7 0.5 1.6 0.0 0.0 4.2 1.1 2.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 3.2 0.1 0.1 0.1 3.6 0.0 9.3 0.6 0.0 0.1 2.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 10.4 1.5 0.0 0.0 0.0 1.9 0.0 0.1 3.6 1.0 0.0 3.4 0.0 331.7 989.4 0.5 0.2 0.0 0.1 1.5 0.0 0.0 0.0 1.0 0.0 0.2 0.5 1.2 3.4 0.0 0.0 0.1 0.3 0.1 0.6 0.4 KCNK17 "K2p17.1, TALK-2, TALK2, TASK-4, TASK4" ENSG00000124780 "Potassium two pore domain channel subfamily K member 17" Q96T54 6 39299001-39314461 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 7.7;thyroid gland: 6.5" "Cell type enhanced" "Detected in some" "dendritic cells: 11.0;Exocrine glandular cells: 7.9;granulocytes: 6.3;Microglial cells: 17.8;Smooth muscle cells: 5.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 34 "plasmacytoid DC: 63.8" "Lineage enriched" "Detected in many" 34 "dendritic cells: 63.8" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 83.8" "Not detected" "Not detected" HPA043892 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA043892: AB_10962838" "unprognostic (5.33e-3)" "unprognostic (6.42e-2)" "unprognostic (1.33e-1)" "unprognostic (1.04e-1)" "unprognostic (1.54e-1)" "unprognostic (3.70e-2)" "unprognostic (3.85e-2)" "unprognostic (4.09e-2)" "unprognostic (4.95e-1)" "unprognostic (2.35e-1)" "unprognostic (1.71e-2)" "unprognostic (2.54e-1)" "unprognostic (3.77e-11)" "unprognostic (5.89e-2)" "unprognostic (5.36e-1)" "unprognostic (2.82e-1)" "unprognostic (3.86e-3)" 0.5 0.3 0.3 0.4 0.4 1.2 0.8 0.3 0.6 0.7 0.2 0.6 1.9 1.2 0.0 0.3 0.8 2.5 5.8 0.2 0.3 0.1 4.0 7.7 0.7 0.4 0.5 0.2 3.9 0.1 1.8 4.0 0.3 0.6 0.5 0.0 0.7 0.2 0.1 0.1 1.1 1.0 0.2 0.7 2.9 0.2 0.5 1.3 6.5 0.5 1.1 0.7 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 83.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 63.8 0.0 0.3 0.3 0.4 0.3 0.6 0.2 0.3 0.4 0.5 0.3 0.2 0.5 0.3 0.0 0.0 2.6 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.9 0.3 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 7.9 0.0 1.8 1.1 0.1 6.3 0.0 0.7 0.2 0.1 0.0 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.9 0.0 17.8 0.2 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.3 5.4 0.0 0.2 0.0 0.0 0.0 0.7 0.1 0.0 0.0 KCNN4 "hIKCa1, hKCa4, hSK4, IK, KCa3.1" ENSG00000104783 "Potassium calcium-activated channel subfamily N member 4" O15554 19 43766533-43781257 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 130.8" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 231.1;Syncytiotrophoblasts: 763.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.7;WM-115: 258.6" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA013367, HPA053841, HPA059622" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 17: WM-115 - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" "HPA013367: , HPA053841: AB_2682278, HPA059622: AB_2684085" "unprognostic (1.23e-2)" "unprognostic (3.22e-2)" "unprognostic (4.29e-1)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.98e-2)" "unprognostic (7.33e-2)" "unprognostic (1.42e-2)" "unprognostic (2.48e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (9.96e-3)" "prognostic unfavorable (1.05e-14)" "unprognostic (3.70e-2)" "unprognostic (2.17e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.75e-4)" 3.6 0.7 1.7 11.8 1.9 18.3 12.4 1.3 1.8 11.8 1.4 18.5 6.4 1.6 1.8 6.5 5.8 3.5 1.1 1.5 1.6 1.4 0.8 7.3 12.5 1.6 1.6 0.6 1.0 0.0 0.7 14.3 1.7 28.6 6.2 0.2 130.8 7.5 0.4 29.1 26.0 0.7 1.9 20.5 35.1 2.7 2.0 5.0 2.1 0.2 9.2 18.2 6.5 2.3 22.4 35.2 0.1 0.2 0.0 2.2 55.0 0.8 1.7 0.7 0.1 0.5 85.7 6.7 9.8 0.9 9.1 13.6 0.0 28.8 1.7 40.9 0.0 29.8 48.6 0.5 0.0 0.3 0.3 0.0 2.9 1.3 6.6 52.7 0.0 0.3 2.6 2.3 0.3 18.7 4.8 17.9 0.2 43.1 42.4 16.8 0.7 21.0 13.0 55.3 0.2 0.1 62.2 70.1 32.6 1.7 0.3 15.1 1.5 12.6 75.9 0.4 45.3 0.1 1.4 2.6 45.9 5.1 258.6 5.8 21.1 0.0 0.5 35.3 0.7 37.3 10.4 5.0 30.7 21.6 6.6 6.3 1.1 0.0 20.1 0.9 15.2 11.2 1.7 1.9 1.3 1.8 1.5 1.6 1.6 1.6 1.7 1.9 2.0 2.3 1.6 0.0 1.9 1.3 24.7 2.8 45.7 79.5 3.4 0.2 69.7 56.6 0.4 7.2 18.4 1.8 4.2 231.1 4.1 22.0 0.0 5.9 1.2 1.7 0.2 4.0 0.0 32.4 1.5 3.9 14.1 2.3 57.1 4.2 0.0 0.0 0.4 0.0 43.7 0.0 1.1 8.9 2.0 7.2 78.2 0.3 0.0 23.3 21.4 1.0 2.5 0.1 1.0 0.5 0.8 63.8 22.3 0.0 22.4 63.5 1.0 0.1 2.2 0.5 0.0 0.3 1.4 0.4 1.4 2.1 2.3 763.3 9.5 0.0 51.1 65.6 KCNQ1 "JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1" ENSG00000053918 "Potassium voltage-gated channel subfamily Q member 1" P51787 11 2444684-2849105 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, Deafness, Diabetes mellitus, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 197.1;stomach 1: 98.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 47.6;Microglial cells: 71.2;Undifferentiated cells: 57.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 33.4;OE19: 41.4;RPMI-8226: 23.2;U-266/70: 11.5;U-937: 13.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB018656, HPA048553, HPA071107" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "Plasma membrane" "CAB018656: AB_2131551, HPA048553: AB_2680438, HPA071107: " "unprognostic (6.02e-2)" "unprognostic (2.48e-1)" "unprognostic (6.39e-3)" "unprognostic (4.38e-1)" "unprognostic (1.86e-1)" "unprognostic (1.83e-1)" "unprognostic (3.46e-2)" "unprognostic (7.36e-2)" "unprognostic (8.07e-2)" "unprognostic (8.81e-2)" "unprognostic (1.58e-1)" "unprognostic (5.39e-2)" "unprognostic (2.46e-3)" "prognostic favorable (9.85e-4)" "unprognostic (3.99e-2)" "unprognostic (4.19e-2)" "unprognostic (5.27e-2)" 5.4 197.1 2.1 9.0 2.4 14.2 3.0 2.4 2.6 16.5 5.7 22.6 47.8 2.9 14.1 2.9 8.9 19.5 28.4 2.6 2.6 25.3 1.8 15.9 5.0 4.1 3.1 1.4 61.2 21.4 5.5 7.6 3.9 6.1 15.2 0.7 20.0 50.2 1.0 1.2 39.7 3.1 4.0 8.2 98.9 1.6 4.2 3.6 71.6 1.6 2.9 14.7 1.6 4.4 0.0 0.1 0.0 5.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 2.6 1.9 5.2 0.0 0.4 0.1 0.7 0.0 0.0 0.4 1.3 0.0 3.7 0.4 0.3 0.0 33.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.7 0.0 0.7 1.3 41.4 0.2 0.1 0.0 23.2 8.0 2.7 0.7 5.6 0.7 0.0 0.0 0.5 0.2 10.3 0.0 0.0 0.3 0.2 0.0 11.5 0.0 0.0 0.0 13.4 0.0 0.7 3.1 3.1 0.0 1.8 0.0 0.8 0.4 0.1 3.8 0.3 1.0 1.2 3.3 0.0 2.8 1.3 0.3 1.0 2.1 2.4 2.4 2.6 2.6 2.6 4.1 3.1 3.9 4.0 4.2 4.4 7.1 3.2 12.9 0.3 8.4 0.6 8.0 4.2 0.0 1.7 6.1 1.8 18.6 14.3 7.1 29.5 0.0 1.1 0.3 34.0 15.6 23.2 2.0 3.3 0.4 6.3 6.6 0.4 13.7 21.7 1.4 1.0 23.4 4.9 19.7 47.6 9.3 1.1 17.3 0.0 20.0 26.1 8.2 25.4 15.9 0.9 0.3 19.6 1.8 71.2 11.0 0.5 1.0 43.7 34.9 15.3 20.2 0.0 6.4 5.2 30.9 2.0 4.4 0.5 6.6 0.4 1.7 0.2 0.2 0.1 1.0 2.1 4.0 16.6 57.8 20.4 KCNS3 Kv9.3 ENSG00000170745 "Potassium voltage-gated channel modifier subfamily S member 3" Q9BQ31 2 17877847-18361616 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lung: 23.5;skeletal muscle: 86.0;tongue: 45.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.9;Enteroendocrine cells: 32.5;Theca cells: 30.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 69.2;RPMI-8226: 28.9;RT4: 48.2;U-266/84: 34.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014864 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Golgi apparatus, Plasma membrane" "HPA014864: AB_1852155" "unprognostic (5.62e-2)" "unprognostic (4.27e-3)" "unprognostic (6.87e-2)" "unprognostic (1.68e-1)" "unprognostic (3.19e-1)" "unprognostic (1.64e-2)" "unprognostic (3.30e-1)" "unprognostic (9.47e-3)" "unprognostic (9.06e-2)" "unprognostic (8.45e-2)" "unprognostic (5.82e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" 2.9 1.1 2.6 3.8 2.9 0.0 6.2 3.9 4.0 7.8 9.5 12.5 3.7 3.2 2.6 6.0 3.9 5.4 6.6 2.9 4.2 5.0 3.8 23.5 0.6 10.5 7.9 1.0 9.8 2.9 1.2 11.0 12.5 6.5 5.0 0.4 11.2 3.1 86.0 5.6 5.4 3.3 5.3 1.0 9.5 3.9 4.3 1.4 2.3 45.5 2.0 6.8 6.3 4.4 8.5 1.4 0.7 0.0 1.6 0.8 3.8 2.8 8.5 1.7 2.0 0.1 17.1 0.0 0.9 3.0 1.9 2.7 20.7 0.1 1.8 0.0 5.7 0.0 0.2 0.1 8.1 0.2 0.7 0.7 12.9 0.1 1.2 15.5 0.4 3.9 0.4 0.0 1.0 2.2 0.0 0.0 10.2 11.5 0.2 2.4 69.2 28.9 1.8 48.2 20.3 0.7 0.0 5.3 6.1 4.8 2.8 0.0 0.2 2.7 0.0 0.2 21.6 0.1 34.9 0.1 15.2 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.9 3.9 4.0 2.9 4.2 10.5 7.9 12.5 5.3 4.3 4.4 3.8 28.9 8.2 0.0 0.0 13.9 16.8 6.9 21.1 0.2 11.5 7.0 0.5 18.6 6.8 11.0 0.0 0.6 0.0 10.9 0.0 21.5 0.3 0.9 0.6 5.9 32.5 0.0 0.3 0.4 3.5 12.1 8.2 0.9 1.3 4.3 2.5 5.4 0.5 0.0 16.9 5.6 14.2 0.0 4.5 1.2 1.5 0.4 21.4 1.9 0.7 0.1 0.0 7.1 2.5 2.4 4.9 3.8 1.2 13.6 4.1 5.5 1.7 0.2 6.6 13.5 10.6 0.3 3.4 8.0 5.8 0.8 0.6 30.6 10.3 7.1 KCNV1 Kv8.1 ENSG00000164794 "Potassium voltage-gated channel modifier subfamily V member 1" Q6PIU1 8 109963636-109975771 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 4.9" "Group enriched" "Detected in some" 6 "Enteroendocrine cells: 7.1;Excitatory neurons: 28.2" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 36.6" HPA067233 Supported "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytokinetic bridge" "HPA067233: " "unprognostic (1.41e-1)" "unprognostic (1.81e-2)" "unprognostic (5.01e-4)" "unprognostic (2.30e-1)" "unprognostic (3.76e-2)" "unprognostic (1.13e-2)" "unprognostic (3.89e-2)" "unprognostic (2.27e-1)" "unprognostic (4.17e-2)" 0.1 0.1 1.9 0.1 4.9 0.5 0.1 0.0 4.6 0.0 0.0 0.5 0.1 0.1 0.5 0.1 0.1 0.1 0.1 3.3 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.4 0.1 0.3 0.2 0.0 0.2 0.4 0.7 0.2 0.1 0.1 0.4 0.3 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 1.1 0.5 0.6 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.4 0.5 0.1 0.0 0.1 0.2 0.1 0.3 0.6 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.6 0.0 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.8 0.2 0.3 0.1 0.1 0.0 0.1 0.4 0.2 0.0 0.2 0.5 0.4 0.3 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.9 4.9 0.0 4.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 7.1 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.5 1.7 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 KEL "CD238, ECE3" ENSG00000197993 "Kell metallo-endopeptidase (Kell blood group)" P23276 7 142941114-142962363 "Blood group antigen proteins, Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 56.3;testis: 32.3" "Cell type enhanced" "Detected in some" "Erythroid cells: 79.7;Oligodendrocytes: 30.1;Squamous epithelial cells: 16.8" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "HEL: 31.7;K-562: 26.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA064442 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Golgi apparatus, Plasma membrane" "Nucleoplasm, Cytosol" "HPA064442: " "unprognostic (5.78e-3)" "unprognostic (1.08e-5)" "unprognostic (5.29e-3)" "unprognostic (4.85e-3)" "unprognostic (9.68e-2)" "unprognostic (1.96e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-2)" "unprognostic (5.18e-2)" "unprognostic (1.08e-2)" "unprognostic (3.71e-2)" "unprognostic (3.57e-2)" "unprognostic (2.29e-3)" "unprognostic (9.24e-2)" "unprognostic (7.05e-2)" "unprognostic (3.32e-2)" "unprognostic (3.25e-3)" 0.2 0.0 1.8 0.8 2.7 56.3 0.3 1.7 2.2 0.9 1.4 0.1 0.0 0.2 0.0 0.8 0.5 0.0 0.3 2.0 1.5 0.6 0.3 0.5 10.6 2.5 2.2 0.2 0.2 0.0 0.2 0.4 2.4 0.3 0.0 0.1 0.6 0.1 0.2 0.1 0.9 0.0 1.9 4.9 0.2 32.3 2.4 1.3 0.3 0.0 6.7 0.1 0.4 2.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 31.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.1 0.5 0.1 0.6 0.0 0.0 0.1 0.0 0.2 0.0 1.4 0.0 0.2 0.0 0.0 0.3 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.7 1.7 2.2 2.0 1.5 2.5 2.2 2.4 1.9 2.4 2.8 0.2 0.0 0.0 0.3 0.0 0.0 1.3 0.2 4.0 0.0 0.3 0.1 0.4 0.0 1.4 3.7 0.0 0.1 0.1 0.0 1.9 0.3 2.4 0.2 0.1 0.1 0.0 79.7 3.0 0.0 0.2 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.8 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 3.1 0.0 1.4 0.2 16.8 0.0 0.1 0.0 0.0 0.0 0.9 KIAA1522 ENSG00000162522 KIAA1522 Q9P206 1 32741830-32774970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 154.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 125.7;hTCEpi: 103.0;RT4: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032050, HPA032051, HPA064839" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA032050: AB_10601764, HPA032051: AB_2674126, HPA064839: AB_2685366" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" "unprognostic (3.09e-2)" "unprognostic (6.41e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.29e-7)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (4.55e-2)" "prognostic favorable (1.29e-5)" "unprognostic (1.35e-2)" "unprognostic (1.35e-1)" "unprognostic (3.98e-1)" "unprognostic (2.12e-1)" 7.9 93.0 14.6 7.0 10.7 1.2 24.3 1.8 15.6 14.5 27.1 42.5 51.7 10.1 12.2 76.7 23.5 16.0 5.1 12.4 6.5 43.9 12.0 18.2 1.2 5.2 5.5 22.3 70.7 37.8 9.1 8.4 4.3 40.9 30.9 1.2 68.3 20.2 3.1 74.1 45.9 6.7 4.2 1.4 61.8 5.1 7.7 8.2 39.4 3.2 12.1 22.2 28.1 8.8 65.7 33.6 5.4 9.3 2.4 4.6 24.6 7.9 15.3 8.9 8.7 37.0 125.7 0.2 32.3 11.6 26.5 95.1 10.3 67.8 4.6 0.2 13.4 13.6 49.4 30.4 4.0 0.2 33.3 1.7 103.0 23.6 28.2 40.1 18.6 2.7 20.1 0.4 4.3 54.3 0.3 0.6 11.0 56.3 20.9 8.7 6.7 16.7 85.8 117.5 4.6 4.7 49.5 70.1 9.7 33.7 74.7 4.3 17.6 14.9 39.3 13.7 17.3 0.8 0.3 0.3 15.2 2.3 17.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 10.7 1.8 15.6 12.4 6.5 5.2 5.5 4.3 4.2 7.7 8.8 5.7 12.8 56.9 5.5 0.6 73.9 37.0 52.7 59.2 0.6 69.8 42.3 3.8 72.9 52.0 27.6 2.1 15.6 1.5 154.4 9.8 47.3 4.2 54.7 5.6 8.7 28.9 1.3 10.2 66.7 5.2 6.7 51.0 50.2 27.8 10.2 4.6 10.6 2.9 0.0 5.2 54.0 48.8 0.8 6.5 5.1 8.7 2.2 7.2 3.7 2.4 0.8 0.0 2.0 0.4 60.7 64.6 4.9 0.3 80.9 84.7 14.8 60.7 0.1 6.6 3.1 7.5 3.8 2.7 59.7 83.1 7.9 2.1 59.9 65.4 99.6 KISS1R "AXOR12, GPR54, HOT7T175" ENSG00000116014 "KISS1 receptor" Q969F8 19 917287-921005 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 8.5" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 41.9" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 15.7;RPMI-8226: 37.4;SCLC-21H: 7.4;SH-SY5Y: 20.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA007156, HPA071913" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" Vesicles "HPA007156: , HPA071913: AB_2686471" "unprognostic (1.54e-1)" "unprognostic (3.01e-2)" "unprognostic (9.42e-2)" "unprognostic (2.15e-1)" "unprognostic (8.46e-3)" "unprognostic (9.23e-2)" "unprognostic (1.65e-2)" "unprognostic (3.23e-1)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (7.17e-2)" "prognostic unfavorable (3.33e-6)" "unprognostic (1.87e-1)" "unprognostic (8.09e-3)" "unprognostic (1.05e-1)" "unprognostic (2.05e-2)" 0.0 0.0 2.9 0.1 1.8 0.0 0.0 0.9 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 3.8 0.3 0.1 0.1 0.1 4.0 2.2 0.0 1.3 0.3 1.1 0.1 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.0 0.4 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.3 4.1 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 15.7 0.0 0.0 0.3 0.1 0.0 0.6 1.2 0.4 1.0 0.0 37.4 0.0 0.0 7.4 20.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 2.9 1.8 0.9 3.4 1.3 3.8 4.0 2.2 3.9 1.0 8.5 0.8 0.1 0.0 0.0 0.0 1.0 0.1 0.1 0.5 0.0 1.1 1.2 1.4 0.5 0.0 0.2 0.0 0.0 0.4 0.2 0.1 0.0 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.2 41.9 0.1 0.0 0.4 0.0 0.1 0.0 0.1 0.7 0.0 0.7 0.0 0.0 0.0 1.5 0.0 0.0 0.3 1.8 0.0 0.0 0.2 1.0 0.0 0.0 0.1 0.0 0.0 4.2 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.4 0.0 0.3 0.3 0.3 1.6 0.9 0.2 0.1 0.2 KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene, receptor tyrosine kinase" P10721 4 54657918-54740715 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 114.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 83.1;granulocytes: 529.3;Inhibitory neurons: 111.2;Ionocytes: 101.7;Melanocytes: 211.7" "Cancer enhanced" "Detected in many" "testis cancer: 28.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 20.3;eosinophil: 12.8;NK-cell: 13.1" "Group enriched" "Detected in many" 7 "granulocytes: 20.3;NK-cells: 13.1" "Group enriched" "Detected in many" 13 "HEL: 247.2;HMC-1: 496.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Plasma membrane" NA NA 49000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 5: Breast - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "CAB003288: AB_2335702, CAB068253: AB_2665717, CAB072867: AB_2665718, HPA004471: AB_1078431, HPA073252: AB_2686589" "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.04e-2)" "unprognostic (8.19e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.33e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.92e-2)" "prognostic favorable (5.63e-4)" "unprognostic (1.34e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 6.6 1.8 8.2 5.3 6.3 6.4 114.9 21.4 6.5 17.6 5.1 13.5 9.2 9.6 5.9 13.0 2.9 20.3 3.4 23.9 5.1 12.4 0.8 21.8 3.4 6.8 12.3 45.0 2.6 1.7 1.9 10.0 8.8 5.6 16.0 3.2 21.4 8.7 1.1 24.5 13.4 10.1 5.9 5.0 17.4 6.2 16.7 3.1 47.1 6.9 6.2 14.5 4.9 5.1 0.0 0.0 3.9 0.0 0.7 0.3 0.0 3.3 4.6 12.6 15.8 0.0 0.0 0.0 0.0 7.3 0.6 0.3 2.6 0.0 10.8 0.0 5.9 247.2 0.0 0.0 0.0 0.0 496.2 0.0 0.0 0.0 0.0 0.0 28.4 4.3 3.5 0.5 0.0 0.0 1.4 2.5 6.9 0.0 0.0 0.8 0.0 0.0 0.0 24.2 6.0 2.1 0.0 0.0 0.0 14.1 0.0 2.6 0.3 0.5 0.0 4.9 0.1 0.4 0.0 0.0 0.5 0.9 0.6 20.3 0.0 12.8 0.1 0.0 2.3 0.0 0.4 0.9 2.3 0.0 0.0 0.0 1.0 13.1 1.4 0.1 0.0 0.2 8.2 6.3 21.4 6.5 23.9 5.1 6.8 12.3 8.8 5.9 16.7 5.1 7.3 6.4 21.9 9.8 1.0 14.3 0.9 0.4 2.2 4.5 83.1 59.2 0.7 4.3 3.6 3.7 0.0 0.1 5.2 0.4 3.9 1.0 0.0 0.2 0.7 9.2 5.4 15.5 0.9 0.0 0.1 2.8 8.6 0.7 529.3 0.5 1.8 0.0 0.3 0.0 111.2 0.5 101.7 0.3 4.2 0.4 1.2 1.6 211.7 14.0 0.2 2.4 0.0 16.1 3.7 0.0 0.1 0.0 3.2 0.5 0.0 0.8 0.1 0.2 0.0 0.7 0.8 0.1 12.3 2.2 3.8 0.3 8.8 63.7 0.6 0.3 KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976468-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 94.7;skin 1: 201.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Basal keratinocytes: 5.0;Basal squamous epithelial cells: 4.6;Breast glandular cells: 9.4;Breast myoepithelial cells: 10.4;Squamous epithelial cells: 5.9;Suprabasal keratinocytes: 10.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 139.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.0;CAPAN-2: 8.0;HaCaT: 31.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" NA NA 3700000 "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: AB_1852607, HPA062126: AB_2684691" "unprognostic (1.88e-2)" "unprognostic (6.41e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (8.06e-5)" "unprognostic (4.33e-3)" "unprognostic (2.28e-1)" "unprognostic (4.44e-3)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.10e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-1)" "unprognostic (4.47e-2)" "unprognostic (1.12e-2)" "unprognostic (5.60e-3)" 7.1 0.1 8.4 0.1 9.2 0.3 11.2 0.9 7.4 19.7 1.0 0.1 0.5 0.7 0.2 94.7 16.3 1.3 0.2 6.5 1.4 12.1 0.1 3.1 0.0 4.3 1.4 0.1 0.1 0.3 0.7 0.0 4.9 0.1 0.0 0.1 21.6 0.2 1.0 201.2 0.0 0.2 2.1 0.8 0.3 0.3 7.4 0.9 0.2 0.0 10.9 0.0 30.9 3.0 5.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.8 8.0 0.0 1.1 0.0 0.1 31.7 0.0 1.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.3 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 8.4 9.2 0.9 7.4 6.5 1.4 4.3 1.4 4.9 2.1 7.4 3.0 0.0 6.4 1.1 0.0 0.0 5.0 0.1 0.5 4.6 0.0 9.4 10.4 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 2.6 0.2 0.0 0.0 1.7 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 5.9 10.7 0.0 0.1 0.0 0.1 2.7 KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.1;lymphoid tissue: 42.9" "Cell type enhanced" "Detected in some" "dendritic cells: 7.2;NK-cells: 6.2;Plasma cells: 4.5;T-cells: 22.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 40 "gdT-cell: 287.4;MAIT T-cell: 111.5;memory CD8 T-cell: 261.2;naive CD8 T-cell: 258.8;NK-cell: 335.8" "Group enriched" "Detected in all" 50 "NK-cells: 335.8;T-cells: 287.4" "Cell line enriched" "Detected in some" 9 "U-698: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB021896: , HPA068877: AB_2686052" "unprognostic (3.34e-4)" "unprognostic (2.65e-4)" "unprognostic (3.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-5)" "unprognostic (5.61e-4)" "unprognostic (1.00e-3)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-10)" "unprognostic (1.24e-2)" "unprognostic (6.32e-2)" "unprognostic (7.59e-2)" "unprognostic (7.08e-10)" 5.5 2.1 1.7 12.6 1.9 22.1 4.1 1.7 2.8 2.2 1.2 3.9 4.7 2.5 2.3 2.2 2.8 7.3 1.8 1.7 2.0 2.0 5.5 12.1 37.0 2.0 1.7 2.4 1.1 0.5 1.1 1.4 1.8 2.5 4.5 0.4 4.4 0.9 0.8 1.3 12.2 1.8 1.7 42.9 7.2 2.5 1.7 9.9 3.6 1.5 19.0 4.5 3.2 2.4 0.3 0.0 0.7 2.8 0.2 7.1 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.2 0.2 0.0 0.7 1.4 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.8 0.3 0.1 0.1 0.0 2.0 0.2 0.3 0.1 0.1 0.8 0.0 0.0 0.0 0.0 64.2 0.2 0.0 0.3 0.4 0.5 0.2 287.4 0.6 111.5 6.2 1.7 261.2 0.6 6.1 2.3 258.8 4.8 335.8 1.3 1.9 0.7 127.9 1.7 1.9 1.7 2.8 1.7 2.0 2.0 1.7 1.8 1.7 1.7 2.4 0.0 0.0 1.3 0.0 2.4 0.0 0.1 0.2 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.2 0.0 0.5 1.8 0.0 0.5 0.0 6.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 22.2 1.0 0.0 0.0 L1CAM "CD171, HSAS, HSAS1, MASA, MIC5, S10, SPG1" ENSG00000198910 "L1 cell adhesion molecule" P32004 X 153861514-153886173 "CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hereditary spastic paraplegia, Hirschsprung disease, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8;intestine: 48.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 84.6;Excitatory neurons: 23.7;Horizontal cells: 33.7;Inhibitory neurons: 23.3;Melanocytes: 44.4" "Cancer enhanced" "Detected in many" "melanoma: 34.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 372.4;BJ hTERT+ SV40 Large T+ RasG12V: 200.8;HeLa: 258.1;RH-30: 162.6;RPTEC TERT1: 218.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010896 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 67000000 "Cluster 24: B-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Plasma membrane" "CAB010896: AB_609903" "unprognostic (1.33e-3)" "unprognostic (3.43e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (8.51e-10)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (9.44e-2)" "prognostic unfavorable (2.36e-6)" "unprognostic (1.13e-1)" "unprognostic (9.12e-2)" "unprognostic (8.52e-3)" "unprognostic (8.02e-2)" "prognostic unfavorable (1.17e-4)" "unprognostic (3.07e-1)" "unprognostic (6.31e-2)" "unprognostic (1.69e-1)" "unprognostic (7.47e-3)" 3.5 27.2 20.4 7.6 23.0 0.5 2.1 23.0 42.8 8.4 0.0 48.5 4.2 2.4 2.1 4.4 3.4 2.4 12.1 12.6 42.4 18.5 0.9 0.6 3.2 9.0 2.5 1.3 2.2 0.1 14.4 0.6 6.1 8.3 4.7 15.7 4.8 9.0 0.9 9.2 13.0 5.4 0.0 0.9 11.3 0.8 3.2 0.7 2.5 2.1 1.8 6.1 9.6 13.2 95.2 7.2 27.6 0.2 0.0 0.0 11.8 131.6 372.4 123.6 200.8 37.8 1.0 0.0 121.8 0.9 103.2 3.9 3.5 2.3 64.1 0.3 1.0 0.0 258.1 6.1 0.4 0.3 20.4 0.9 1.6 18.7 12.9 0.2 0.1 0.1 0.3 0.3 0.6 127.9 0.4 2.6 6.5 0.4 4.7 0.2 162.6 0.9 218.4 1.9 81.4 53.0 73.4 64.2 54.1 61.0 6.7 1.7 0.3 0.1 52.6 5.8 63.7 1.1 1.6 1.0 0.9 1.1 105.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 23.0 23.0 42.8 12.6 42.4 9.0 2.5 6.1 0.0 3.2 13.2 0.4 0.0 0.0 2.6 1.3 1.1 0.1 0.6 3.4 11.6 0.0 0.4 1.2 0.0 0.0 84.6 4.2 0.3 0.1 0.0 0.0 0.5 0.0 0.3 0.1 1.9 0.0 0.0 23.7 0.0 0.2 1.3 0.0 0.6 0.0 0.0 1.4 0.0 0.1 33.7 23.3 0.0 0.0 0.0 1.1 0.0 0.9 0.3 44.4 5.6 0.0 1.5 0.0 1.5 1.7 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.1 10.4 0.0 2.2 0.6 0.4 0.1 0.0 1.3 0.1 1.5 0.0 0.0 0.1 LAIR1 CD305 ENSG00000167613 "Leukocyte associated immunoglobulin like receptor 1" Q6GTX8 19 54351384-54370558 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.1;lymphoid tissue: 46.3" "Cell type enhanced" "Detected in many" "dendritic cells: 106.6;granulocytes: 109.3;Hofbauer cells: 190.9;Kupffer cells: 100.9;Macrophages: 128.9;NK-cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HMC-1: 7.5;Karpas-707: 19.4;THP-1: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011155 Enhanced Supported "Plasma membrane" NA NA 350000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA011155: AB_1852685" "unprognostic (1.91e-1)" "unprognostic (1.12e-2)" "unprognostic (2.81e-2)" "unprognostic (1.25e-2)" "unprognostic (2.03e-2)" "unprognostic (4.38e-2)" "unprognostic (2.16e-2)" "unprognostic (1.74e-1)" "unprognostic (5.00e-2)" "unprognostic (2.24e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (5.01e-5)" "unprognostic (1.72e-1)" "unprognostic (2.72e-3)" "unprognostic (3.52e-2)" "unprognostic (5.22e-2)" 23.3 11.6 0.5 3.0 0.3 4.4 12.3 1.6 1.3 4.1 0.5 6.9 0.4 3.8 0.2 2.6 5.5 0.9 3.8 0.4 0.6 4.6 3.5 28.1 5.8 1.0 0.8 2.2 3.8 0.1 4.4 1.0 1.0 5.4 0.2 0.1 5.8 0.2 1.3 2.1 14.3 2.0 0.4 46.3 5.0 1.7 1.1 3.9 3.3 0.1 0.9 6.3 3.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 3.3 7.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 19.4 0.0 0.0 2.6 1.8 0.0 0.0 0.0 2.6 0.2 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 22.9 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 3.2 0.3 13.1 4.2 11.7 7.7 9.8 4.8 2.1 2.3 4.1 0.1 5.8 3.4 4.4 0.7 6.3 11.0 11.2 1.7 3.8 0.5 0.3 1.6 1.3 0.4 0.6 1.0 0.8 1.0 0.4 1.1 0.9 1.9 16.0 25.6 0.3 26.1 0.6 0.6 0.2 0.0 5.6 1.1 2.9 1.5 1.5 11.2 0.0 37.5 5.3 106.6 0.2 0.0 0.1 32.2 0.6 0.7 5.0 0.0 10.9 0.4 0.0 5.2 2.5 0.0 0.7 109.3 0.6 3.6 1.2 190.9 1.7 0.5 0.0 0.0 100.9 17.7 26.1 0.3 128.9 0.0 13.1 22.5 0.9 98.9 0.0 0.6 0.1 0.0 0.0 5.1 0.7 0.3 0.3 11.0 15.4 0.0 0.9 1.3 2.9 1.0 0.4 1.1 10.0 32.1 0.2 0.2 0.9 LAMTOR1 "C11orf59, FLJ20625, p18, p27RF-Rho, Pdro, Ragulator1" ENSG00000149357 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1" Q6IAA8 11 72085895-72103297 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002997 Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 160000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus" "Vesicles, Plasma membrane" "HPA002997: AB_1845531" "unprognostic (7.32e-2)" "unprognostic (1.79e-1)" "unprognostic (3.94e-2)" "unprognostic (3.77e-2)" "unprognostic (2.30e-1)" "unprognostic (2.71e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.00e-1)" "unprognostic (2.18e-1)" "unprognostic (1.94e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-3)" "unprognostic (1.78e-3)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.04e-1)" 100.7 143.8 171.2 69.1 177.8 118.6 96.2 173.2 180.4 87.0 162.1 88.6 67.5 86.5 90.0 114.1 74.9 65.8 131.9 163.5 169.5 129.5 114.2 91.3 80.6 177.4 177.2 81.5 85.6 87.0 92.0 67.4 174.9 102.4 76.5 46.6 85.8 71.7 126.4 89.9 82.5 73.7 175.4 130.9 96.6 41.2 176.1 75.4 112.3 109.3 79.4 88.5 77.9 172.5 94.2 181.0 97.3 132.0 224.7 152.3 97.6 129.0 201.6 206.2 151.7 230.9 139.7 93.1 162.3 216.9 214.2 138.1 171.1 260.1 155.8 117.8 99.3 245.6 108.5 156.5 291.4 97.2 147.7 252.3 199.2 224.4 224.0 116.4 173.1 102.5 104.1 96.0 211.4 295.6 86.2 146.1 93.9 291.8 194.9 73.7 178.9 78.8 246.8 195.1 65.7 103.3 127.6 127.5 343.7 106.4 192.6 93.2 125.3 137.5 98.0 323.8 93.0 111.6 139.0 80.4 81.8 81.8 113.0 113.4 414.3 274.1 80.6 228.8 77.7 132.1 75.6 81.1 332.6 146.2 63.4 77.9 229.5 122.8 180.6 197.1 98.8 397.5 171.2 177.8 173.2 180.4 163.5 169.5 177.4 177.2 174.9 175.4 176.1 172.5 132.6 44.8 71.6 9.1 109.7 55.7 161.7 271.1 117.8 58.5 159.9 195.7 66.4 121.5 120.2 128.8 12.5 266.5 110.7 235.4 295.4 276.4 12.4 61.2 98.9 134.9 116.4 133.5 9.8 340.2 300.1 111.6 71.4 85.2 97.7 71.5 142.1 86.9 468.0 77.4 12.9 140.2 170.9 248.5 111.6 19.2 107.8 311.5 113.8 8.4 413.6 223.7 177.1 10.1 24.2 307.3 202.6 102.7 87.9 193.4 230.3 370.9 61.0 56.1 111.7 102.5 116.3 58.7 103.3 126.1 55.4 282.0 89.4 178.5 170.8 157.2 LASP1 "Lasp-1, MLN50" ENSG00000002834 "LIM and SH3 protein 1" Q14847 17 38869859-38921770 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 591.7;Proximal enterocytes: 292.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012072, CAB022049" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 9400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "Focal adhesion sites" "CAB022049: , HPA012072: AB_1852714" "unprognostic (1.23e-1)" "unprognostic (2.09e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.47e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (2.41e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-1)" "unprognostic (9.60e-2)" "unprognostic (9.87e-3)" "unprognostic (1.01e-1)" "unprognostic (9.65e-3)" "unprognostic (1.29e-3)" "unprognostic (3.95e-2)" "unprognostic (1.60e-3)" "unprognostic (4.53e-2)" 86.4 38.0 60.8 75.9 56.7 126.4 55.5 45.5 56.7 46.9 48.6 93.0 131.9 43.8 32.3 45.9 46.0 56.8 40.3 56.1 61.0 55.9 76.4 68.6 76.1 56.2 63.5 48.5 59.0 25.5 33.0 81.4 59.0 30.9 92.3 26.8 44.8 33.9 23.7 44.4 168.8 51.2 52.9 74.3 96.2 23.9 67.4 74.1 34.9 27.7 78.2 53.2 37.3 50.1 214.1 441.0 124.1 111.0 182.8 196.9 218.7 267.8 257.8 274.5 198.5 134.3 225.8 98.8 214.1 417.3 154.9 332.4 58.5 204.1 239.6 71.6 31.6 47.5 124.2 235.8 173.0 110.4 134.1 176.3 69.6 234.6 66.1 170.7 188.0 59.0 81.9 30.3 389.4 72.0 127.1 163.6 63.0 189.9 109.4 70.7 67.6 123.8 332.7 187.9 19.0 45.4 159.3 160.5 134.7 233.5 255.7 128.2 331.4 160.0 233.0 189.7 162.0 79.7 115.8 75.2 170.2 96.7 197.2 21.8 31.4 35.0 30.7 33.1 20.3 11.7 15.2 20.4 27.3 10.8 12.7 19.8 67.0 34.2 42.1 20.5 21.4 32.5 60.8 56.7 45.5 56.7 56.1 61.0 56.2 63.5 59.0 52.9 67.4 50.1 54.5 41.7 27.6 17.6 41.8 41.8 21.5 26.0 51.8 66.4 82.4 43.2 1.1 55.8 30.4 73.5 10.4 7.5 69.5 225.2 17.6 65.7 89.6 27.5 31.7 54.3 86.5 21.0 16.4 76.5 59.1 50.1 119.3 46.4 52.0 37.4 64.6 115.4 83.9 26.9 16.0 101.9 28.5 127.7 73.0 591.7 51.9 71.9 35.6 24.4 94.3 22.2 164.8 11.1 4.4 111.0 116.4 39.9 32.8 24.2 292.7 72.9 57.3 23.1 65.7 65.4 53.4 2.9 5.7 62.2 28.4 6.4 63.4 19.2 97.8 31.8 LAT LAT1 ENSG00000213658 "Linker for activation of T cells" O43561 16 28984826-28990784 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 117.9" "Group enriched" "Detected in many" 6 "dendritic cells: 80.7;granulocytes: 78.9;Macrophages: 55.9;NK-cells: 152.4;T-cells: 151.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 19 "basophil: 307.7;gdT-cell: 303.4;MAIT T-cell: 212.5;memory CD4 T-cell: 295.1;memory CD8 T-cell: 307.2;naive CD4 T-cell: 276.0;naive CD8 T-cell: 266.9;NK-cell: 114.6;T-reg: 410.8" "Group enriched" "Detected in all" 142 "granulocytes: 307.7;NK-cells: 114.6;T-cells: 410.8" "Cell line enhanced" "Detected in many" "HEL: 189.8;HMC-1: 765.9;MOLT-4: 279.5" "Not detected" "Not detected" "CAB002223, HPA011157, CAB012978, CAB079960" Enhanced Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 140000 "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Golgi apparatus" "CAB002223: AB_563852, CAB012978: , CAB079960: , HPA011157: AB_1079237" "unprognostic (4.35e-3)" "unprognostic (5.17e-3)" "unprognostic (1.25e-2)" "unprognostic (1.21e-1)" "unprognostic (1.62e-1)" "unprognostic (7.15e-5)" "unprognostic (1.17e-1)" "unprognostic (5.17e-2)" "unprognostic (1.27e-1)" "unprognostic (3.25e-2)" "unprognostic (1.52e-3)" "unprognostic (5.33e-2)" "unprognostic (1.02e-8)" "unprognostic (1.04e-2)" "unprognostic (5.58e-2)" "unprognostic (3.25e-1)" "unprognostic (1.51e-4)" 8.1 4.4 9.1 23.9 9.6 17.5 6.6 9.0 11.9 15.6 8.1 31.3 9.2 19.3 5.2 8.1 11.6 9.6 3.9 9.2 8.5 15.3 10.5 14.1 65.9 9.2 8.5 7.7 5.7 2.0 14.2 3.9 9.0 21.6 5.2 3.5 7.8 9.5 4.2 10.7 22.7 5.7 8.0 32.0 13.4 4.1 9.7 117.9 17.6 1.6 29.0 24.7 13.3 8.9 1.0 2.3 1.5 2.5 3.7 2.4 4.9 5.5 1.4 1.7 2.2 2.3 3.0 0.7 7.2 2.2 0.6 2.9 2.6 1.3 0.8 1.6 3.3 189.8 5.4 3.3 1.0 5.9 765.9 2.1 3.8 1.7 0.7 2.8 0.9 62.7 2.6 21.7 0.8 5.6 279.5 38.3 3.4 0.4 2.7 3.2 0.8 24.9 1.9 1.6 5.3 1.0 0.9 1.8 2.7 1.4 2.7 31.7 3.6 3.6 18.0 3.9 1.3 7.6 7.0 3.1 45.5 2.7 2.9 307.7 1.4 0.7 303.4 1.5 212.5 1.7 295.1 307.2 1.1 1.7 276.0 266.9 14.6 114.6 1.3 1.9 410.8 196.5 9.1 9.6 9.0 11.9 9.2 8.5 9.2 8.5 9.0 8.0 9.7 8.9 5.2 0.0 13.1 4.6 6.2 7.1 2.1 1.1 2.8 11.0 3.7 4.3 1.7 7.2 3.1 9.2 6.2 2.6 80.7 1.2 1.9 1.7 0.3 1.5 2.3 4.7 0.0 16.6 4.7 0.5 0.9 3.0 7.7 2.7 78.9 4.9 8.6 2.9 14.3 6.7 5.5 1.5 0.0 7.3 9.4 0.1 1.5 55.9 10.6 5.6 9.2 3.0 152.4 3.0 3.5 1.0 0.7 0.7 17.0 2.2 1.3 1.3 1.3 9.6 0.0 3.0 3.8 1.7 2.1 1.9 5.3 2.7 151.7 1.7 1.4 1.3 LAT2 "HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5" ENSG00000086730 "Linker for activation of T cells family member 2" Q9GZY6 7 74199652-74229834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.3;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "B-cells: 90.6;granulocytes: 171.6;Hofbauer cells: 82.7;Kupffer cells: 71.1;Langerhans cells: 81.9;Macrophages: 89.1;monocytes: 89.6;NK-cells: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 871.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 192.2;REH: 205.7;RPMI-8226: 73.3;THP-1: 186.5;U-937: 177.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003462 Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA003462: AB_1079238" "unprognostic (1.24e-2)" "unprognostic (1.14e-2)" "unprognostic (1.32e-2)" "unprognostic (3.55e-3)" "unprognostic (1.09e-1)" "unprognostic (3.30e-3)" "unprognostic (2.79e-2)" "unprognostic (1.33e-1)" "unprognostic (9.27e-2)" "unprognostic (1.19e-1)" "unprognostic (6.34e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" 6.8 5.4 9.7 37.7 11.1 61.3 3.8 11.8 12.8 3.7 9.1 6.5 6.3 2.9 2.5 3.6 4.2 9.1 2.3 10.3 12.2 3.3 4.8 19.2 51.6 18.4 13.6 1.7 3.0 2.2 3.0 7.4 17.7 7.1 7.7 1.2 4.5 3.5 3.3 3.0 13.6 8.8 16.5 47.0 6.5 2.0 15.3 12.2 2.8 2.4 56.6 10.1 2.5 20.1 1.7 1.1 1.1 3.1 0.3 0.0 1.1 1.4 1.2 0.6 0.7 2.3 28.9 19.6 0.4 0.5 6.1 1.2 0.4 1.1 0.6 31.4 1.2 8.6 1.8 1.8 0.1 56.1 55.6 0.4 0.8 2.1 0.6 1.2 0.3 1.1 1.6 9.3 0.5 1.7 1.3 192.2 0.9 5.5 2.0 205.7 1.1 73.3 0.2 1.7 0.9 0.8 0.6 1.2 1.2 0.9 1.1 186.5 2.1 2.1 19.9 0.8 1.8 0.9 6.2 32.2 9.4 177.6 1.5 871.6 276.6 46.0 8.8 159.0 0.9 169.3 2.3 1.4 225.2 191.1 1.0 2.9 491.0 73.9 93.9 8.9 4.9 214.7 9.7 11.1 11.8 12.8 10.3 12.2 18.4 13.6 17.7 16.5 15.3 20.1 1.3 3.2 16.2 0.7 90.6 3.4 0.7 0.0 0.6 0.3 1.0 1.9 1.1 5.7 3.1 3.7 0.0 0.6 47.8 0.2 0.0 0.3 2.4 1.3 0.6 3.9 7.8 16.6 1.7 0.2 1.1 1.7 1.1 2.1 171.6 0.4 3.9 4.5 82.7 0.0 1.4 0.8 0.0 71.1 81.9 3.4 0.0 89.1 1.8 20.6 89.6 0.2 70.0 0.5 0.9 0.6 0.1 0.7 18.7 1.2 0.1 0.2 5.9 1.3 0.0 1.9 0.9 0.4 1.4 0.1 2.6 1.2 27.7 0.3 0.8 0.4 LINGO1 "FLJ14594, LERN1, LRRN6A" ENSG00000169783 "Leucine rich repeat and Ig domain containing 1" Q96FE5 15 77613027-77820900 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.1" "Group enriched" "Detected in many" 4 "Astrocytes: 271.0;Excitatory neurons: 271.6;Horizontal cells: 132.9;Inhibitory neurons: 220.5;Microglial cells: 167.7;Oligodendrocyte precursor cells: 240.8;Oligodendrocytes: 324.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 37.4;basal ganglia: 43.9;cerebral cortex: 56.1;hippocampal formation: 49.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 23.9;AN3-CA: 20.1;HAP1: 30.2;HEK 293: 21.0;MCF7: 13.5;NTERA-2: 56.9;SuSa: 21.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074653 Enhanced Supported "Plasma membrane" NA NA 25000 "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA074653: AB_2686706" "unprognostic (1.06e-1)" "unprognostic (7.07e-2)" "unprognostic (2.16e-2)" "unprognostic (1.48e-2)" "unprognostic (3.09e-1)" "unprognostic (2.20e-1)" "unprognostic (2.84e-2)" "unprognostic (3.77e-2)" "unprognostic (3.40e-1)" "unprognostic (1.10e-1)" "unprognostic (7.36e-2)" "unprognostic (2.74e-2)" "prognostic unfavorable (3.23e-7)" "unprognostic (2.07e-1)" "unprognostic (7.06e-2)" "unprognostic (2.85e-1)" "unprognostic (2.59e-2)" 3.9 1.1 37.4 1.2 43.9 0.0 3.5 0.0 56.1 4.6 0.0 2.2 1.5 4.5 2.2 0.9 2.7 2.1 11.8 49.1 0.0 4.2 0.8 1.0 0.7 0.0 0.0 2.3 2.5 4.1 1.9 6.7 0.0 1.6 0.8 16.2 3.2 2.0 0.8 2.8 1.7 4.6 0.0 3.3 1.4 5.3 0.2 0.3 2.2 1.4 0.3 2.3 2.9 4.6 0.0 2.1 23.9 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.4 0.0 0.4 0.1 30.2 0.0 0.0 0.0 21.0 0.0 0.0 0.4 0.3 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 3.3 0.2 0.0 13.5 0.0 0.0 56.9 1.3 0.0 0.0 0.0 0.5 0.0 0.0 4.2 1.2 0.1 2.4 4.9 21.6 0.3 0.4 2.1 0.0 5.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 43.9 0.0 56.1 49.1 0.0 0.0 0.0 0.0 0.0 0.2 4.6 2.1 0.0 0.0 271.0 0.0 0.3 0.1 0.0 0.0 21.8 0.7 0.3 7.3 1.5 0.0 0.0 2.1 0.1 0.0 1.8 0.0 0.3 8.6 0.8 3.7 2.3 0.0 0.0 271.6 0.2 0.2 1.8 0.0 0.2 0.0 14.9 4.2 0.0 0.3 132.9 220.5 0.3 0.0 0.0 0.0 16.5 0.3 0.1 3.6 167.7 0.0 51.1 0.0 240.8 324.2 0.2 7.7 0.4 0.0 0.0 0.0 0.0 0.0 19.5 26.3 0.0 21.9 0.2 3.1 0.0 0.1 0.3 0.1 0.5 0.2 0.0 LIPI "CT17, LPDL, mPA-PLA1beta, PLA1C, PRED5" ENSG00000188992 "Lipase I" Q6XZB0 21 14108813-14210955 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 167 "epididymis: 421.0" "Group enriched" "Detected in some" 4 "Early spermatids: 1.7;Excitatory neurons: 1.5;Inhibitory neurons: 2.0;Microglial cells: 1.9;Oligodendrocyte precursor cells: 2.0" "Cancer enriched" "Detected in single" 6 "thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049665 Supported "Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA049665: " "unprognostic (2.60e-2)" "unprognostic (3.49e-1)" "unprognostic (1.12e-3)" "unprognostic (1.14e-1)" "unprognostic (1.08e-2)" "unprognostic (1.19e-1)" "unprognostic (2.05e-2)" "unprognostic (1.68e-1)" "unprognostic (4.53e-2)" "unprognostic (2.90e-1)" "unprognostic (3.64e-13)" "unprognostic (2.82e-1)" "unprognostic (4.14e-2)" "unprognostic (2.90e-1)" "unprognostic (7.87e-3)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.2 0.0 0.5 421.0 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.2 0.7 0.4 0.0 0.1 0.6 0.1 0.4 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LPAR1 "edg-2, EDG2, Gpcr26, GPR26, LPA1, Mrec1.3, rec.1.3, vzg-1" ENSG00000198121 "Lysophosphatidic acid receptor 1" Q92633 9 110873263-111038458 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 358.4;choroid plexus: 122.2" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 626.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 9.1;eosinophil: 19.0" "Group enriched" "Detected in many" 6 "granulocytes: 19.0;monocytes: 9.1" "Cell line enhanced" "Detected in many" "ASC diff: 582.0;ASC TERT1: 337.0;BJ hTERT+: 426.7;HSkMC: 246.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050667 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear speckles" "Plasma membrane" "HPA050667: " "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (4.79e-2)" "unprognostic (6.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" "unprognostic (2.17e-2)" "unprognostic (2.10e-1)" "unprognostic (1.40e-2)" "unprognostic (4.13e-2)" "unprognostic (1.02e-1)" "unprognostic (4.29e-3)" "unprognostic (2.12e-2)" "unprognostic (5.42e-3)" "unprognostic (2.78e-2)" "unprognostic (9.97e-3)" "unprognostic (1.65e-1)" 30.5 13.3 251.0 18.8 315.0 0.2 25.9 208.8 318.6 57.7 122.2 24.5 13.9 17.0 17.1 15.2 15.8 14.1 24.1 199.5 201.3 9.6 2.6 16.3 17.6 299.6 277.5 12.1 6.6 2.2 5.0 38.8 249.2 21.0 18.3 0.8 16.7 23.6 6.6 20.1 18.3 20.5 224.0 14.8 11.8 6.9 266.2 6.8 16.5 17.5 17.2 27.6 31.7 358.4 11.7 22.2 30.4 0.1 582.0 337.0 0.0 151.6 426.7 104.1 46.8 3.0 1.8 0.0 0.1 157.7 18.6 45.5 0.4 118.5 85.0 0.0 4.1 0.0 1.1 0.0 157.1 0.1 0.2 246.6 6.8 51.4 96.9 62.3 1.8 0.2 0.0 0.2 80.8 0.1 0.0 0.1 5.9 0.0 121.6 0.1 22.4 0.0 23.5 20.6 0.9 7.2 3.1 0.0 0.0 6.2 10.4 0.5 0.1 48.9 1.3 35.3 0.1 1.5 0.0 0.0 7.4 0.0 54.9 1.5 9.1 19.0 0.0 3.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 1.9 2.1 1.3 0.2 0.0 2.1 251.0 315.0 208.8 318.6 199.5 201.3 299.6 277.5 249.2 224.0 266.2 358.4 1.9 0.0 1.1 6.2 0.2 13.0 15.5 8.5 4.0 0.0 3.4 6.0 1.4 1.5 9.1 0.0 0.0 0.5 0.3 6.6 1.9 1.8 1.4 3.6 40.4 1.9 0.0 0.0 1.0 2.9 0.4 61.4 6.1 8.7 0.0 0.0 2.5 0.0 3.3 0.0 15.6 3.7 4.1 4.1 15.1 2.7 38.8 3.6 14.2 141.5 12.0 1.0 1.0 1.0 626.8 2.0 2.9 70.7 0.7 12.7 4.5 0.2 3.0 0.2 0.0 13.3 6.3 0.3 2.4 15.2 9.2 0.8 1.2 0.2 4.2 6.7 LPAR3 "Edg-7, EDG7, HOFNH30, LP-A3, LPA3, RP4-678I3" ENSG00000171517 "Lysophosphatidic acid receptor 3" Q9UBY5 1 84811602-84893206 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 36.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 15.6;Cardiomyocytes: 31.2;Endometrial ciliated cells: 36.9;Glandular and luminal cells: 51.6;Respiratory ciliated cells: 18.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 24.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 19.0;HBEC3-KT: 22.2;hTCEpi: 25.0;NTERA-2: 20.3;PC-3: 19.0;SK-MEL-30: 24.1" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA013421 Supported "Plasma membrane" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA013421: AB_1847990" "unprognostic (2.85e-2)" "unprognostic (1.67e-1)" "unprognostic (2.66e-1)" "unprognostic (4.42e-1)" "unprognostic (2.72e-2)" "unprognostic (6.46e-3)" "unprognostic (1.15e-1)" "unprognostic (1.29e-2)" "unprognostic (1.20e-1)" "prognostic favorable (4.31e-5)" "unprognostic (1.11e-2)" "unprognostic (7.52e-2)" "unprognostic (1.13e-4)" "unprognostic (4.11e-2)" "unprognostic (1.19e-1)" "unprognostic (4.27e-2)" "unprognostic (5.43e-2)" 0.0 1.3 2.4 0.2 3.3 0.3 0.9 2.1 5.1 10.4 2.0 0.5 0.1 2.9 5.9 7.0 36.4 0.5 10.5 3.8 1.7 0.0 0.1 1.5 0.2 8.2 2.7 1.5 10.4 0.1 0.1 1.4 2.6 13.4 0.6 0.1 5.7 1.0 0.4 4.3 0.1 0.1 1.9 0.1 0.3 10.4 2.3 2.3 0.2 0.0 1.0 5.1 5.3 3.2 0.7 0.1 0.0 0.1 0.0 0.0 0.7 0.3 1.7 1.4 1.1 0.0 0.0 0.1 0.3 0.0 0.0 0.4 19.0 22.2 1.4 0.2 3.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 25.0 4.8 1.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 20.3 0.0 19.0 0.0 0.0 0.0 0.0 5.8 1.3 1.1 0.0 0.5 24.1 1.4 0.0 2.0 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.4 3.3 2.1 5.1 3.8 1.7 8.2 2.7 2.6 1.9 2.3 3.2 0.0 0.0 0.5 12.7 0.0 3.4 15.6 5.6 7.4 0.0 1.8 3.7 31.2 0.0 6.5 0.0 0.0 0.5 0.1 0.3 0.0 0.0 2.9 36.9 3.6 0.5 0.0 0.0 0.2 1.3 0.0 1.2 0.0 51.6 0.0 0.5 0.4 0.0 0.4 0.0 0.1 0.2 2.0 0.0 1.5 2.4 0.6 0.7 1.8 1.9 0.0 0.0 0.0 0.0 0.1 1.0 0.3 0.0 0.0 13.1 0.0 0.0 18.7 0.0 0.0 0.0 1.2 0.7 3.4 7.7 9.1 0.1 1.5 0.6 0.4 13.5 LPAR4 "GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9" ENSG00000147145 "Lysophosphatidic acid receptor 4" Q99677 X 78747709-78757094 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8;ovary: 3.6" "Cell type enhanced" "Detected in some" "Astrocytes: 10.1;Fibroblasts: 4.2;Leydig cells: 20.2;Oligodendrocyte precursor cells: 3.5;Skeletal myocytes: 3.6" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 6.3" "Lineage enriched" "Detected in single" 19 "granulocytes: 6.3" "Cell line enhanced" "Detected in some" "AF22: 9.3;NTERA-2: 15.2;RH-30: 6.4;U-937: 3.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046563, HPA054951, HPA055571" Uncertain Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies, Vesicles" "HPA046563: AB_2732529, HPA054951: AB_2682646, HPA055571: AB_2682853" "unprognostic (1.62e-1)" "unprognostic (3.53e-1)" "unprognostic (1.58e-1)" "unprognostic (5.81e-4)" "unprognostic (3.12e-2)" "unprognostic (4.85e-3)" "unprognostic (2.81e-1)" "unprognostic (2.57e-1)" "unprognostic (6.75e-2)" "unprognostic (6.73e-2)" "unprognostic (8.91e-2)" "unprognostic (4.86e-4)" "unprognostic (2.99e-5)" "unprognostic (9.27e-3)" "unprognostic (1.00e-1)" "unprognostic (3.58e-2)" "unprognostic (6.03e-3)" 0.5 0.0 1.8 0.4 1.3 0.3 0.8 1.1 1.7 0.6 1.1 0.3 0.0 1.1 0.3 0.6 0.3 0.8 0.7 3.0 1.2 0.1 0.1 0.1 0.0 1.8 1.7 3.6 0.4 0.0 0.1 0.0 1.3 0.2 0.4 0.1 0.3 0.1 0.0 0.5 0.3 0.5 2.6 0.1 0.4 0.3 1.1 0.7 0.1 0.3 0.4 0.3 0.2 3.8 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.6 1.0 1.2 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.6 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.1 2.1 0.0 0.4 1.7 15.2 0.0 0.2 0.8 6.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 3.4 0.0 2.6 0.0 0.0 0.2 0.0 0.6 1.2 0.0 0.7 0.7 3.7 1.5 6.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 1.3 1.1 1.7 3.0 1.2 1.8 1.7 1.3 2.6 1.1 3.8 1.2 0.0 0.0 10.1 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.1 0.8 0.0 0.0 0.1 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.4 0.5 20.2 0.1 1.8 1.0 0.6 1.0 0.0 3.5 0.1 0.0 0.0 2.6 0.1 0.2 0.0 0.1 0.0 0.0 0.0 3.6 0.4 0.0 0.3 1.5 0.4 0.0 0.4 0.2 0.0 0.2 LRFN2 "FIGLER2, KIAA1246, SALM1" ENSG00000156564 "Leucine rich repeat and fibronectin type III domain containing 2" Q9ULH4 6 40391591-40587364 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 6.4;retina: 3.2" "Cell type enhanced" "Detected in some" "Astrocytes: 24.2;Cone photoreceptor cells: 62.6;Excitatory neurons: 111.5;Inhibitory neurons: 62.8;Oligodendrocyte precursor cells: 49.8" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 6.4;cerebral cortex: 5.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "REH: 1.7;SH-SY5Y: 4.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA076660 Enhanced Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA076660: AB_2686812" "unprognostic (1.93e-2)" "unprognostic (2.04e-1)" "unprognostic (3.61e-2)" "unprognostic (4.58e-4)" "unprognostic (3.10e-1)" "unprognostic (1.21e-1)" "unprognostic (2.69e-1)" "unprognostic (5.75e-3)" "unprognostic (4.94e-2)" "unprognostic (1.80e-1)" "unprognostic (9.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (1.64e-1)" "unprognostic (2.98e-1)" "unprognostic (1.16e-1)" "unprognostic (2.66e-4)" 0.0 0.3 1.6 0.0 6.4 0.3 0.0 0.0 5.9 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.7 0.2 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 1.7 0.0 0.0 0.0 0.1 0.7 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.6 6.4 0.0 5.9 1.3 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.0 0.0 0.0 24.2 0.0 0.0 0.0 0.0 0.0 10.8 0.1 0.3 0.6 0.0 0.1 0.0 62.6 0.4 0.3 0.1 0.0 0.0 1.5 0.0 0.0 0.1 4.2 0.0 111.5 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 62.8 1.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 3.7 0.0 0.8 0.0 49.8 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 1.9 0.0 1.0 0.0 0.3 0.2 0.0 0.1 0.1 LRRC26 bA350O14.10 ENSG00000184709 "Leucine rich repeat containing 26" Q2I0M4 9 137168758-137170051 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "salivary gland: 290.0" "Cell type enriched" "Detected in many" 5 "Intestinal goblet cells: 598.0" "Cancer enriched" "Detected in many" 5 "prostate cancer: 47.6" "Region enriched" "Detected in single" 5 "cerebellum: 2.6" "Immune cell enriched" "Detected in single" 1177 "plasmacytoid DC: 117.6" "Lineage enriched" "Detected in single" 1177 "dendritic cells: 117.6" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 130.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA056312 Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Nucleoli fibrillar center" "HPA056312: AB_2683098" "unprognostic (1.75e-1)" "unprognostic (2.28e-2)" "unprognostic (1.04e-2)" "prognostic favorable (4.82e-6)" "unprognostic (3.39e-1)" "unprognostic (1.67e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "prognostic favorable (3.48e-4)" "unprognostic (3.27e-1)" "unprognostic (2.29e-1)" 0.1 0.0 0.2 0.3 0.4 0.0 7.3 2.6 0.5 0.4 0.0 11.2 1.7 1.1 0.0 2.8 1.1 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.1 53.1 0.5 0.0 290.0 0.5 0.0 5.1 7.2 0.0 0.2 0.1 5.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 5.4 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.9 0.1 0.3 0.7 20.8 0.1 130.9 0.0 0.0 1.0 0.2 0.5 6.0 0.0 0.0 2.7 0.5 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.6 0.0 0.5 0.2 0.4 2.6 0.5 0.1 0.5 0.0 0.1 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.3 1.2 1.0 1.7 0.5 0.0 0.0 101.2 64.4 0.4 4.3 1.0 0.0 0.0 0.1 81.8 15.2 1.9 0.1 0.5 13.0 1.6 1.0 9.0 0.0 0.1 0.4 0.0 0.4 9.2 21.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 598.0 4.1 0.0 0.9 1.1 0.0 1.4 56.9 0.0 0.6 0.0 0.0 0.0 0.1 0.2 11.8 0.0 0.6 28.4 28.8 0.1 0.4 0.0 0.0 0.0 0.4 0.2 2.8 3.5 0.3 0.0 0.6 0.0 24.3 3.7 LSR "ILDR3, LISCH7" ENSG00000105699 "Lipolysis stimulated lipoprotein receptor" Q86X29 19 35248330-35267964 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 335.6;Ductal cells: 260.5;Exocrine glandular cells: 278.9;Pancreatic endocrine cells: 336.0;Paneth cells: 273.6;Syncytiotrophoblasts: 248.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 500.5;CACO-2: 215.6;CAPAN-2: 225.3;HaCaT: 203.9;OE19: 300.4;RT4: 198.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007270, HPA075309" Approved Supported "Plasma membrane" NA NA 3500000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA007270: AB_1079253, HPA075309: " "unprognostic (3.90e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (2.67e-3)" "unprognostic (2.28e-2)" "unprognostic (6.07e-3)" "unprognostic (1.55e-1)" "unprognostic (9.84e-2)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (3.42e-2)" "prognostic favorable (8.09e-4)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (1.54e-2)" 15.7 31.3 15.7 17.8 13.6 3.6 25.4 13.2 14.7 20.4 39.0 96.9 85.0 14.4 13.9 60.0 29.7 36.4 7.7 12.5 13.2 28.9 144.8 30.0 14.4 17.1 14.8 6.4 114.2 16.8 27.3 46.9 15.5 25.6 43.7 8.6 69.4 18.5 4.4 51.9 75.0 5.3 12.9 17.9 133.1 27.2 17.7 6.6 32.9 2.7 14.1 29.9 29.3 14.8 500.5 8.1 0.7 1.0 1.4 0.5 86.8 1.2 1.9 2.2 1.6 215.6 225.3 19.6 73.0 1.3 7.2 203.9 44.3 75.0 0.3 30.1 82.6 0.2 6.5 96.1 1.7 0.3 0.9 1.0 81.2 2.0 24.2 1.0 0.8 0.6 80.2 17.2 1.1 177.4 0.9 1.1 69.0 300.4 3.2 3.8 0.8 54.6 46.2 198.2 37.7 1.4 40.9 130.5 35.8 21.7 112.5 2.6 0.4 3.9 44.7 3.1 2.2 27.2 52.5 45.7 3.4 0.8 12.4 6.4 0.2 0.1 2.5 0.0 2.6 4.3 5.8 5.4 0.1 3.0 4.2 4.9 0.0 5.6 0.0 0.2 4.1 2.9 15.7 13.6 13.2 14.7 12.5 13.2 17.1 14.8 15.5 12.9 17.7 14.8 38.2 16.0 21.7 0.3 26.3 51.7 123.4 90.7 50.1 2.1 60.9 49.7 5.6 78.6 71.2 36.8 16.7 210.3 4.7 335.6 11.7 260.5 9.4 41.7 27.4 44.6 56.4 3.2 0.8 278.9 93.0 11.9 214.1 61.5 31.1 30.3 20.3 89.7 21.7 0.0 0.9 145.5 73.2 2.2 14.3 2.9 6.5 4.6 14.2 22.5 7.2 11.5 3.1 1.5 0.8 336.0 273.6 3.4 41.1 113.6 117.8 24.6 43.8 12.3 0.0 4.1 24.4 7.9 19.1 57.2 51.7 248.0 24.3 3.4 124.2 206.3 LST1 "B144, D6S49E, LST-1" ENSG00000204482 "Leukocyte specific transcript 1" O00453 6 31586124-31588909 "Predicted intracellular proteins, Predicted membrane proteins" "Cell shape, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 100.3;lung: 48.8;lymphoid tissue: 181.9" "Group enriched" "Detected in many" 11 "Hofbauer cells: 407.1;Kupffer cells: 1326.9;Langerhans cells: 1240.5;Macrophages: 871.6;monocytes: 1096.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1746.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 39.3;HMC-1: 73.6;MOLT-4: 39.6;NB-4: 76.2;THP-1: 179.9;U-937: 92.9" "Low region specificity" "Detected in all" HPA079451 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA079451: " "unprognostic (1.08e-2)" "prognostic favorable (7.89e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-3)" "unprognostic (3.13e-1)" "unprognostic (3.92e-2)" "unprognostic (3.65e-1)" "unprognostic (7.06e-3)" "unprognostic (2.81e-3)" "unprognostic (2.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.97e-5)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.62e-4)" "unprognostic (1.03e-1)" "unprognostic (1.95e-1)" 15.2 10.2 4.3 22.0 4.3 100.3 7.9 4.6 7.2 5.6 5.0 7.9 7.1 3.7 1.4 5.5 6.6 3.1 7.6 4.6 5.5 10.8 14.4 48.8 13.8 6.1 4.9 3.0 4.7 0.9 6.1 4.7 6.6 8.9 3.0 0.5 6.9 2.3 2.1 7.8 15.0 5.1 5.4 181.9 5.7 1.8 5.2 15.1 4.6 1.9 7.1 9.1 5.1 6.0 0.3 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 2.5 0.6 0.0 0.0 0.5 0.3 0.4 0.3 12.9 0.0 39.3 0.0 0.0 0.7 29.3 73.6 0.0 0.3 0.1 1.2 0.3 0.9 0.8 0.1 0.2 0.0 0.0 39.6 76.2 0.1 0.0 0.0 18.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 179.9 0.3 0.0 0.4 0.0 0.2 0.1 0.0 5.9 0.0 92.9 0.0 112.2 419.7 681.6 9.4 1273.9 80.7 32.8 15.9 20.2 392.9 21.9 10.9 9.0 1133.0 21.6 1746.7 69.9 12.0 541.6 4.3 4.3 4.6 7.2 4.6 5.5 6.1 4.9 6.6 5.4 5.2 6.0 5.4 35.3 86.7 0.7 43.7 35.2 0.3 0.2 0.0 0.3 3.2 12.2 1.9 7.2 13.0 11.0 0.0 2.9 42.8 1.0 0.0 0.6 1.5 0.4 1.9 12.9 0.0 15.1 0.2 0.2 3.8 9.2 1.5 0.4 70.3 0.1 22.9 5.8 407.1 0.0 0.3 0.0 2.0 1326.9 1240.5 5.4 3.7 871.6 44.4 24.4 1096.6 0.7 60.8 0.5 0.1 0.1 1.1 1.2 4.7 1.0 0.0 3.8 11.0 0.2 26.3 2.2 2.8 2.4 4.6 0.4 28.3 5.3 43.6 0.0 0.4 0.3 LTB4R2 "BLT2, BLTR2, JULF2, NOP9" ENSG00000213906 "Leukotriene B4 receptor 2" Q9NPC1 14 24305734-24312053 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 37.7;skin 1: 46.4" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 18.2;Squamous epithelial cells: 15.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 15.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB022689, HPA029680, HPA072921" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Nucleoplasm "CAB022689: , HPA029680: AB_10603013, HPA072921: AB_2686557" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" "unprognostic (9.53e-2)" "unprognostic (8.82e-2)" "unprognostic (1.42e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-1)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.37e-1)" "unprognostic (1.48e-3)" "unprognostic (7.18e-2)" "unprognostic (7.05e-11)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "unprognostic (4.23e-2)" "unprognostic (1.19e-1)" 5.1 5.8 0.4 2.1 0.5 5.4 4.7 0.5 0.4 15.8 0.4 2.7 2.6 3.0 0.8 37.7 4.0 0.9 2.2 0.3 0.3 2.8 4.0 4.7 2.0 1.2 0.4 4.9 4.7 0.2 3.9 1.0 0.5 5.0 0.5 2.1 11.7 1.2 3.0 46.4 5.1 0.5 0.5 13.5 2.7 4.2 0.6 1.7 3.9 0.1 3.2 2.7 21.6 0.8 2.4 3.9 1.6 1.7 0.3 0.5 7.1 0.8 0.4 1.2 0.7 3.1 1.3 2.9 1.4 0.5 1.6 15.0 1.1 2.5 0.8 3.7 4.4 2.0 3.7 1.5 0.4 3.4 3.7 0.5 3.1 1.7 2.0 1.0 0.5 5.3 2.6 3.3 0.5 4.4 1.8 3.5 0.9 0.1 4.7 7.4 1.5 1.7 0.3 2.8 3.1 1.5 1.5 1.8 1.3 1.7 3.4 2.5 1.5 2.3 2.8 3.6 1.3 7.1 2.1 4.7 0.5 5.5 1.8 0.0 0.5 0.3 0.6 0.3 0.3 0.0 0.5 0.5 0.5 0.0 0.3 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.4 0.5 0.5 0.4 0.3 0.3 1.2 0.4 0.5 0.5 0.6 0.8 2.3 0.0 0.0 0.0 0.7 0.3 3.4 0.1 18.2 0.4 0.6 1.3 0.0 0.0 0.0 1.8 0.0 0.2 1.2 0.5 0.0 0.2 0.0 1.9 0.2 1.6 1.8 2.1 0.0 1.4 0.1 0.5 1.5 0.4 0.0 0.2 1.1 1.0 0.7 3.3 0.0 0.4 0.0 1.9 0.0 0.0 0.3 1.8 0.0 0.0 0.2 0.2 1.0 0.0 0.0 0.4 1.2 0.0 3.0 0.4 1.1 0.3 0.7 0.5 0.0 0.3 0.2 0.9 0.2 15.7 0.1 0.3 2.3 0.3 0.8 0.8 LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879835-56014169 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.8;lymphoid tissue: 85.4" "Cell type enhanced" "Detected in many" "B-cells: 237.5;Kupffer cells: 183.7;Macrophages: 226.0;monocytes: 182.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 64.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 198.4;HMC-1: 193.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 770000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" 17.2 7.3 3.9 79.2 4.0 73.8 9.2 7.4 8.7 11.0 7.8 14.2 36.3 6.2 4.8 8.6 10.0 23.5 5.4 4.4 5.5 5.9 14.9 28.2 49.2 9.4 7.2 3.6 9.5 6.3 4.8 23.5 8.3 5.6 13.3 8.9 17.0 9.7 1.6 3.7 31.6 14.2 7.2 85.4 13.3 3.1 9.0 10.4 10.6 4.4 53.1 29.7 5.7 11.2 47.2 24.6 6.9 0.7 0.5 0.0 43.6 34.6 54.7 21.0 15.7 18.0 15.5 41.2 15.0 12.1 15.3 19.3 22.2 23.8 14.6 70.0 19.8 198.4 6.9 5.5 4.0 20.6 193.4 0.8 7.8 0.6 13.6 13.1 27.2 0.0 98.3 90.2 3.0 3.3 0.1 21.5 38.6 72.9 2.1 3.3 9.6 5.0 9.8 24.9 4.5 74.8 17.3 0.1 7.5 44.9 3.4 41.4 33.1 0.0 10.0 0.1 15.0 26.4 13.2 102.4 1.5 38.8 1.7 4.5 12.2 22.7 1.6 28.3 1.3 15.9 0.3 0.6 10.3 16.1 0.2 0.7 64.4 4.3 49.1 16.2 0.0 5.0 3.9 4.0 7.4 8.7 4.4 5.5 9.4 7.2 8.3 7.2 9.0 11.2 21.0 35.3 37.5 27.7 237.5 5.4 23.8 32.4 4.6 6.3 10.3 7.0 2.2 18.6 44.5 9.2 2.1 2.9 130.0 14.5 0.0 21.8 0.9 14.6 26.2 28.1 6.0 40.4 1.1 53.0 65.2 13.6 18.8 15.9 72.8 0.5 22.9 13.2 126.6 0.0 2.5 14.1 14.2 183.7 96.1 2.4 3.4 226.0 5.4 92.8 182.6 54.3 94.7 13.0 1.7 40.7 13.3 1.2 58.9 62.9 26.0 2.1 40.9 2.6 19.7 3.7 6.4 1.2 2.1 4.9 5.8 38.7 25.0 62.5 17.1 82.4 MACF1 "ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF" ENSG00000127603 "Microtubule actin crosslinking factor 1" Q9UPN3 1 39081316-39487177 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" Actin-binding "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1079.0;Cone photoreceptor cells: 779.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013713, HPA068064, HPA068103" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 25000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cell Junctions, Actin filaments" "HPA013713: AB_10600821, HPA068064: AB_2685946, HPA068103: AB_2685953" "unprognostic (2.71e-1)" "unprognostic (3.14e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (9.00e-2)" "unprognostic (6.19e-3)" "unprognostic (1.32e-1)" "unprognostic (7.40e-3)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (1.34e-1)" "unprognostic (3.98e-1)" "prognostic favorable (2.77e-5)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (8.57e-2)" "unprognostic (4.22e-2)" 69.1 62.5 172.0 27.7 197.5 36.2 54.6 174.6 181.6 65.9 119.1 148.6 18.6 130.3 48.7 46.4 92.0 46.4 127.0 159.7 166.1 85.7 63.8 183.6 35.9 190.2 179.0 92.6 51.2 96.9 69.3 34.6 182.9 68.2 25.1 121.2 57.7 41.6 73.0 121.0 62.6 54.2 155.6 84.9 71.3 50.2 193.2 39.3 73.3 55.2 22.8 80.3 62.7 185.3 48.1 54.9 66.7 29.3 53.8 47.3 29.8 62.2 79.4 38.0 33.7 34.3 56.5 24.4 64.6 84.0 62.1 30.6 12.5 45.7 51.2 43.5 33.1 34.0 43.4 56.5 66.0 30.8 15.9 37.0 46.5 105.1 54.3 83.5 104.7 52.0 63.2 25.7 137.0 16.0 23.3 52.7 95.8 20.0 31.7 38.5 89.6 4.5 206.0 50.8 38.2 38.6 24.9 17.2 62.5 76.3 7.5 37.9 115.1 61.6 48.5 28.8 101.9 19.4 19.7 28.8 101.0 32.6 55.2 7.5 1.3 3.8 12.2 2.7 5.9 2.2 5.8 7.8 1.8 3.8 4.7 6.1 1.3 6.5 2.9 2.5 3.0 2.0 172.0 197.5 174.6 181.6 159.7 166.1 190.2 179.0 182.9 155.6 193.2 185.3 135.3 150.6 128.2 1079.0 68.7 154.4 74.9 43.0 60.3 387.7 52.5 50.9 246.1 61.5 70.7 80.9 779.8 52.6 120.5 35.4 0.0 113.3 9.6 140.6 124.4 164.3 36.1 57.6 320.6 114.6 62.1 108.2 65.2 180.1 77.7 194.3 132.1 47.9 52.1 117.8 367.5 27.2 22.4 59.7 46.3 11.8 43.8 74.8 71.2 342.9 59.0 107.8 158.6 494.6 410.7 193.5 17.7 112.5 81.0 89.7 22.5 20.6 71.3 398.5 105.2 95.5 136.7 62.6 33.7 43.5 191.5 69.9 131.2 76.5 19.7 78.8 MAP3K7 "MEKK7, TAK1" ENSG00000135341 "Mitogen-activated protein kinase kinase kinase 7" O43318 6 90513573-90587072 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007633, HPA075335" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Nuclear speckles, Plasma membrane" "HPA007633: AB_1079359, HPA075335: " "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (1.35e-1)" "unprognostic (6.48e-2)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (9.77e-2)" "unprognostic (6.51e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (2.56e-3)" "unprognostic (4.76e-2)" "unprognostic (1.95e-1)" "unprognostic (2.08e-1)" "unprognostic (1.17e-1)" 11.8 12.5 13.1 12.5 15.1 8.7 14.3 15.6 17.3 14.3 11.7 11.6 9.2 16.6 16.5 10.6 11.0 12.7 16.9 14.7 14.9 11.4 11.6 10.4 16.4 15.3 13.7 15.8 9.7 16.3 13.0 17.4 15.8 14.9 10.9 23.5 12.1 13.3 16.9 13.9 9.8 14.0 15.3 17.6 10.8 9.9 13.8 20.8 14.7 18.4 16.8 14.3 12.2 22.4 16.7 14.4 41.3 35.6 29.5 39.1 29.0 32.7 37.7 28.8 36.1 18.6 15.5 36.9 20.4 35.6 25.6 17.3 26.3 25.5 48.7 19.0 27.7 32.9 19.9 24.9 30.8 36.9 24.4 32.5 30.5 28.2 34.2 33.1 27.4 31.8 67.0 29.3 41.8 20.3 17.2 31.2 34.0 25.7 18.0 29.3 73.9 18.0 24.2 18.4 20.8 29.5 22.9 15.6 24.8 32.2 15.5 64.7 26.5 23.3 14.7 21.6 30.9 25.9 24.7 15.8 35.7 39.7 35.0 18.2 11.5 18.4 12.8 15.9 14.5 13.0 12.3 12.5 14.6 9.9 13.7 13.4 11.5 17.9 17.6 8.9 20.8 13.4 13.1 15.1 15.6 17.3 14.7 14.9 15.3 13.7 15.8 15.3 13.8 22.4 16.1 16.0 26.9 47.0 24.3 36.3 20.8 19.5 21.6 23.3 17.9 12.3 31.0 14.3 16.9 16.5 27.1 31.8 17.8 12.4 7.9 17.6 3.6 10.9 19.8 21.2 12.1 14.1 85.7 20.9 34.6 23.2 16.3 14.8 13.9 25.9 25.7 20.7 24.3 28.6 63.8 13.7 20.3 27.3 24.6 3.2 26.8 21.7 21.4 36.5 35.2 19.6 16.5 50.8 137.2 20.1 9.1 41.0 18.8 30.1 11.1 16.6 21.4 21.5 19.7 28.0 18.5 25.9 24.9 21.3 37.2 48.4 22.7 18.1 15.1 24.8 MAPT "DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau" ENSG00000186868 "Microtubule associated protein tau" P10636 17 45894527-46028334 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Alzheimer disease, Disease variant, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.7;skeletal muscle: 79.0" "Cell type enhanced" "Detected in many" "Astrocytes: 142.4;Bipolar cells: 314.4;Early spermatids: 199.9;Excitatory neurons: 189.2;Horizontal cells: 361.7;Inhibitory neurons: 153.7;Late spermatids: 416.6;Muller glia cells: 145.7;Oligodendrocytes: 163.8" "Cancer enhanced" "Detected in many" "breast cancer: 9.5;glioma: 13.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "HDLM-2: 69.0;SCLC-21H: 21.1;T-47d: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000151, HPA048895, HPA069524, HPA069570, CAB072344" Enhanced Supported "Nuclear speckles,Plasma membrane" "Secreted to blood" NA NA 7100 "Cluster 35: T-regs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Nuclear speckles" "CAB000151: , CAB072344: , HPA048895: AB_2680550, HPA069524: AB_2686145, HPA069570: AB_2686155" "unprognostic (1.78e-3)" "unprognostic (7.51e-2)" "unprognostic (3.71e-2)" "unprognostic (8.40e-5)" "unprognostic (1.40e-1)" "unprognostic (1.31e-2)" "unprognostic (4.06e-5)" "unprognostic (6.04e-2)" "unprognostic (2.19e-2)" "unprognostic (3.49e-2)" "unprognostic (3.88e-3)" "unprognostic (2.65e-1)" "unprognostic (1.72e-3)" "unprognostic (6.53e-2)" "unprognostic (3.43e-1)" "unprognostic (1.85e-2)" "unprognostic (5.47e-2)" 4.7 4.3 26.2 0.3 27.1 0.0 9.1 8.3 67.7 2.4 0.0 8.4 0.5 1.0 0.2 8.4 1.0 0.8 9.4 30.0 20.4 14.7 0.6 0.8 0.3 11.6 11.4 0.6 1.5 2.9 29.5 3.4 22.4 5.4 0.3 17.6 8.5 3.4 79.0 6.3 1.8 0.3 2.7 0.4 1.7 20.3 14.8 0.4 0.9 27.4 0.2 10.2 2.3 19.7 2.9 0.5 0.3 6.4 0.3 0.9 1.8 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.6 0.4 0.5 0.1 2.3 0.3 0.0 69.0 3.4 0.0 0.3 4.2 0.0 0.1 0.1 0.0 0.5 0.1 0.3 0.1 0.0 4.4 0.7 3.6 0.0 7.7 1.0 0.2 0.2 0.7 2.0 0.0 4.0 8.5 0.0 9.1 21.1 9.1 2.5 0.0 1.8 1.0 34.7 0.1 0.1 0.3 0.8 1.7 0.3 0.9 0.3 0.0 0.6 2.0 0.5 0.1 0.0 0.0 0.2 0.7 0.2 0.0 0.1 0.5 0.0 0.0 0.2 0.3 0.2 0.1 1.7 0.0 0.7 0.0 26.2 27.1 8.3 67.7 30.0 20.4 11.6 11.4 22.4 2.7 14.8 19.7 1.9 0.0 9.8 142.4 1.0 1.0 1.4 0.2 1.2 314.4 26.7 21.2 35.2 0.0 0.1 1.8 64.6 0.2 0.4 0.1 7.9 0.5 199.9 0.4 1.7 1.8 0.0 0.0 189.2 0.4 9.1 3.7 0.5 1.3 4.5 1.6 1.1 0.5 0.3 361.7 153.7 0.0 2.0 0.6 1.7 416.6 2.8 0.8 5.4 8.4 0.7 145.7 0.0 129.7 163.8 0.6 0.0 2.6 0.1 2.5 0.1 76.1 0.0 28.3 0.0 28.2 6.0 18.4 8.1 22.7 3.3 0.3 1.5 0.8 0.3 0.6 MARCHF7 "AXOT, MARCH-VII, MARCH7, RNF177" ENSG00000136536 "Membrane associated ring-CH-type finger 7" Q9H992 2 159712457-159771027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 33.3;Cardiomyocytes: 88.4;Cytotrophoblasts: 36.2;dendritic cells: 28.2;Extravillous trophoblasts: 38.8;Hofbauer cells: 34.0;Syncytiotrophoblasts: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014275, HPA022152" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA014275: AB_10599820, HPA022152: AB_10601107" "unprognostic (2.42e-1)" "unprognostic (2.24e-1)" "unprognostic (1.02e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (2.46e-2)" "unprognostic (6.42e-2)" "unprognostic (3.44e-1)" "unprognostic (3.17e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (1.84e-4)" "unprognostic (1.41e-3)" "unprognostic (1.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.61e-1)" 38.3 30.0 16.4 37.9 21.7 43.2 48.2 32.3 21.5 38.6 25.1 33.2 30.0 45.0 34.2 67.3 37.5 38.1 48.9 15.8 16.1 32.8 40.1 38.2 47.9 17.4 17.1 47.5 22.3 36.6 22.7 46.9 17.7 38.1 36.9 37.9 26.9 36.3 55.2 38.6 30.0 50.6 14.9 45.1 33.5 62.0 17.1 60.8 47.5 44.1 52.2 39.0 37.5 21.8 50.3 35.3 88.7 40.7 61.9 81.9 89.1 83.9 81.1 82.5 73.9 70.9 57.5 71.0 36.8 84.2 46.8 61.3 55.4 74.5 102.9 75.9 43.2 96.0 53.8 53.3 60.7 79.9 72.6 72.7 83.0 99.5 86.5 92.5 99.3 50.7 75.6 65.6 82.9 44.2 52.4 73.8 84.6 54.6 47.3 75.0 64.5 59.3 74.6 112.1 51.9 48.6 65.6 48.2 67.0 94.3 56.9 94.4 93.5 86.9 51.9 53.9 47.2 51.5 61.0 96.8 54.1 46.8 84.0 83.5 28.8 59.6 28.6 29.5 33.3 27.6 30.4 32.4 27.6 26.4 36.3 35.9 127.5 39.4 43.4 22.3 34.3 30.9 16.4 21.7 32.3 21.5 15.8 16.1 17.4 17.1 17.7 14.9 17.1 21.8 33.3 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.4 0.0 0.0 0.0 0.0 36.2 28.2 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 38.8 13.5 0.0 0.0 0.0 0.0 0.0 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 44.2 5.8 0.0 0.0 0.0 MARCKS "80K-L, MACS, PKCSL" ENSG00000277443 "Myristoylated alanine rich protein kinase C substrate" P29966 6 113857345-113863475 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 12.7;neutrophil: 18.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 405.8;TIME: 326.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022062, HPA054820, HPA067595, HPA069443" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 19000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Endoplasmic reticulum, Cytosol" "CAB022062: AB_309681, HPA054820: AB_2682613, HPA067595: AB_2732772, HPA069443: AB_2732133" "unprognostic (4.71e-1)" "unprognostic (1.91e-2)" "unprognostic (2.46e-1)" "unprognostic (5.51e-3)" "unprognostic (8.22e-3)" "unprognostic (2.38e-2)" "prognostic unfavorable (2.78e-8)" "unprognostic (7.82e-2)" "unprognostic (2.57e-1)" "unprognostic (6.92e-2)" "unprognostic (2.27e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (4.85e-4)" "unprognostic (1.36e-3)" "unprognostic (2.77e-2)" "unprognostic (8.07e-2)" "unprognostic (2.70e-2)" 42.8 16.8 65.1 58.2 64.1 104.6 50.2 73.2 78.5 31.9 21.6 75.7 38.9 31.2 13.5 45.1 27.3 35.8 18.2 56.8 89.2 24.6 26.1 35.0 45.4 81.0 87.6 39.0 42.4 7.0 20.6 63.0 73.1 37.8 68.2 22.0 28.0 18.0 15.7 32.1 43.3 30.1 106.8 57.0 62.8 10.3 85.5 44.8 16.2 12.9 45.3 86.2 34.5 102.8 39.2 22.6 405.8 22.3 134.0 86.6 2.2 123.0 171.4 84.9 140.6 40.7 54.1 0.1 25.3 228.0 67.3 118.0 67.9 35.7 109.7 0.3 40.2 0.0 22.2 53.3 89.2 10.3 0.7 90.2 68.8 81.8 77.4 231.9 243.1 0.4 4.6 107.6 122.1 0.4 1.3 0.3 52.7 43.5 29.4 0.2 40.7 4.1 26.9 73.6 56.4 163.4 78.7 39.6 89.6 95.0 2.1 11.3 326.0 78.3 0.5 129.9 212.7 288.3 22.4 11.4 60.2 55.8 153.4 0.0 3.9 0.0 0.0 12.7 0.0 4.6 0.0 0.0 1.1 1.9 0.0 0.0 18.7 0.0 7.5 0.0 0.0 0.5 65.1 64.1 73.2 78.5 56.8 89.2 81.0 87.6 73.1 106.8 85.5 102.8 211.2 9.6 15.5 44.7 139.0 504.1 540.7 232.3 275.4 157.0 213.2 176.7 16.6 57.2 115.0 38.6 29.2 7.2 5.5 629.5 37.2 144.3 55.7 111.2 444.0 271.6 336.3 2.5 33.0 229.9 11.2 372.6 135.1 130.4 2.5 526.1 236.0 8.8 371.6 84.1 21.0 369.4 126.1 286.3 605.5 35.7 120.5 381.3 273.9 60.0 447.2 315.5 2.1 194.5 9.7 208.1 223.1 67.0 105.2 380.1 89.9 6.9 145.0 37.7 39.5 89.8 222.8 22.7 16.2 326.3 638.5 29.4 22.3 62.3 352.3 620.2 MARK2 "EMK1, PAR-1, PAR-1B, Par1b" ENSG00000072518 "Microtubule affinity regulating kinase 2" Q7KZI7 11 63838928-63911020 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038790, HPA074905" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA038790: AB_10674840, HPA074905: AB_2686722" "unprognostic (1.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.13e-2)" "unprognostic (3.82e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (2.73e-3)" "unprognostic (4.41e-1)" "unprognostic (5.79e-2)" "unprognostic (3.94e-3)" "unprognostic (3.77e-1)" "unprognostic (5.20e-3)" "unprognostic (5.15e-3)" "unprognostic (6.78e-2)" "unprognostic (1.03e-1)" "unprognostic (2.40e-1)" 11.3 13.8 12.6 21.1 16.1 24.0 16.8 8.1 16.3 18.5 10.8 25.9 26.1 14.6 7.7 51.8 16.6 14.1 20.9 14.9 9.3 13.9 13.1 17.0 21.5 11.8 9.3 12.0 22.4 19.4 19.8 14.9 11.5 20.5 22.4 8.8 27.0 13.1 20.8 40.9 25.1 16.3 7.3 24.1 20.9 10.6 9.5 23.2 19.5 13.7 24.0 19.3 25.0 17.9 52.0 34.1 26.6 28.6 14.6 18.6 35.2 20.8 20.0 29.5 22.3 34.1 49.5 37.8 35.6 20.8 32.0 57.5 26.9 28.7 24.6 26.7 20.9 40.7 23.9 20.3 17.0 45.9 51.4 10.9 36.8 27.0 21.4 13.5 24.7 33.6 35.7 36.5 19.5 64.4 49.3 29.9 31.7 36.0 24.2 39.9 20.4 39.7 19.1 39.8 37.9 25.4 34.7 90.2 24.3 28.9 65.1 26.4 22.7 30.3 19.1 39.6 23.4 24.5 28.8 36.7 20.1 23.2 25.3 1.4 0.7 2.1 1.3 0.7 2.1 0.9 1.0 1.3 1.0 1.6 0.8 0.9 3.6 1.6 1.1 0.9 0.6 0.7 12.6 16.1 8.1 16.3 14.9 9.3 11.8 9.3 11.5 7.3 9.5 17.9 17.3 6.4 6.8 29.7 18.5 25.2 21.1 9.1 19.4 26.8 30.0 18.2 12.8 27.1 11.9 20.2 8.4 26.0 33.4 90.3 1.9 20.2 0.6 29.5 15.8 14.7 29.9 14.7 43.6 21.4 20.6 11.7 27.0 41.0 17.2 21.1 13.6 13.0 17.9 20.2 30.3 39.9 10.2 26.7 18.5 0.9 12.8 25.0 3.6 29.0 17.0 18.8 36.0 31.7 51.8 27.3 39.4 10.9 15.6 30.4 33.4 8.1 14.5 18.1 19.7 19.6 13.1 9.1 18.4 39.9 34.4 65.0 23.6 16.0 33.6 44.3 MC5R ENSG00000176136 "Melanocortin 5 receptor" P33032 18 13824149-13827323 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.4;lymphoid tissue: 1.0" "Cell type enriched" "Detected in single" 17 "Squamous epithelial cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-138 MG: 1.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA042365, HPA058088" Approved Supported "Plasma membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA042365: AB_2677961, HPA058088: " "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" "unprognostic (8.77e-2)" "unprognostic (7.10e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-1)" 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 2.4 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 MCEMP1 "C19orf59, MGC132456" ENSG00000183019 "Mast cell expressed membrane protein 1" Q8IX19 19 7676628-7679826 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 65.9;lung: 74.2;lymphoid tissue: 35.1" "Cell type enriched" "Detected in some" 4 "Macrophages: 147.5" "Cancer enhanced" "Detected in many" "lung cancer: 3.7" "Region enhanced" "Detected in single" "cerebral cortex: 2.1" "Group enriched" "Detected in some" 5 "classical monocyte: 102.1;neutrophil: 45.9" "Group enriched" "Detected in many" 5 "granulocytes: 45.9;monocytes: 102.1" "Group enriched" "Detected in some" 6 "THP-1: 53.7;U-937: 166.6" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected" "Not detected" HPA014731 Enhanced Supported "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA014731: AB_1845619" "unprognostic (4.84e-2)" "unprognostic (9.81e-4)" "unprognostic (2.41e-1)" "unprognostic (4.36e-2)" "unprognostic (8.85e-3)" "unprognostic (2.62e-3)" "unprognostic (5.57e-3)" "unprognostic (1.42e-1)" "unprognostic (2.19e-1)" "unprognostic (4.36e-2)" "unprognostic (1.77e-2)" "unprognostic (3.50e-1)" "unprognostic (2.69e-5)" "unprognostic (1.15e-2)" "unprognostic (7.37e-2)" "unprognostic (1.93e-2)" "unprognostic (7.95e-2)" 4.0 0.5 0.0 19.7 0.0 65.9 0.5 0.0 2.1 0.1 0.0 0.4 0.2 0.1 0.0 0.5 1.7 0.6 1.3 0.0 0.0 0.7 1.5 74.2 0.1 0.0 0.0 0.2 0.7 0.0 0.2 1.8 0.9 0.5 0.1 0.0 0.8 0.0 0.3 0.1 0.6 5.1 0.0 35.1 0.9 0.2 0.7 0.9 0.4 1.5 0.1 4.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 1.4 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 53.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 166.6 0.0 0.0 102.1 2.8 0.2 6.0 0.0 0.0 0.3 0.0 14.9 0.0 0.0 0.3 45.9 0.6 0.4 0.9 0.2 38.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.9 0.0 0.7 0.0 0.4 19.2 34.5 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 11.2 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.1 0.0 0.0 2.2 0.0 3.6 0.0 0.0 1.0 2.9 0.0 0.0 7.6 0.0 0.0 0.3 28.8 0.0 0.0 0.0 0.0 28.3 0.0 0.1 0.0 147.5 0.0 0.0 26.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.2 5.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.8 2.9 0.0 0.0 0.1 MDGA1 "GPIM, MAMDC3" ENSG00000112139 "MAM domain containing glycosylphosphatidylinositol anchor 1" Q8NFP4 6 37630679-37699306 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 79.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.0;Cone photoreceptor cells: 50.1;Horizontal cells: 57.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 9 "cerebellum: 79.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 12.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031235, HPA050382" Enhanced Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Golgi apparatus" "HPA031235: AB_10603017, HPA050382: AB_2681108" "unprognostic (4.67e-2)" "unprognostic (6.97e-3)" "unprognostic (3.24e-1)" "unprognostic (5.69e-4)" "unprognostic (2.75e-2)" "unprognostic (2.41e-1)" "unprognostic (1.45e-2)" "unprognostic (2.00e-1)" "unprognostic (2.02e-2)" "unprognostic (1.45e-1)" "unprognostic (2.16e-2)" "unprognostic (3.00e-1)" "unprognostic (1.52e-5)" "unprognostic (9.19e-3)" "unprognostic (5.28e-3)" "unprognostic (3.80e-3)" "unprognostic (4.60e-2)" 2.6 2.9 4.2 2.6 3.9 0.3 1.6 79.9 5.3 5.4 0.0 2.6 0.5 3.4 1.8 3.7 2.7 3.2 2.3 8.8 4.9 1.2 0.6 3.1 2.6 4.3 4.7 6.5 2.4 4.1 4.8 0.3 7.4 2.1 1.1 4.0 1.1 1.3 1.1 4.9 2.8 2.5 1.0 3.1 2.0 1.5 2.1 0.8 1.4 1.7 2.1 1.9 4.4 3.2 0.2 3.5 4.8 2.4 12.3 4.3 2.2 2.8 2.2 3.5 3.2 0.0 0.0 0.7 0.5 1.7 3.0 5.4 0.5 0.0 1.0 4.9 3.4 0.0 0.3 0.0 0.5 0.0 1.1 1.0 0.0 1.4 0.0 6.8 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.4 0.0 0.1 0.4 5.9 1.7 0.0 0.8 3.7 4.3 0.0 1.5 0.3 2.6 0.2 3.1 0.6 0.3 3.4 1.4 1.2 4.3 0.0 0.1 0.0 4.2 1.0 2.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.1 4.2 3.9 79.9 5.3 8.8 4.9 4.3 4.7 7.4 1.0 2.1 3.2 3.0 9.6 0.5 12.7 2.0 2.3 2.4 0.7 1.2 34.0 0.4 0.6 5.7 1.5 0.8 3.7 50.1 0.2 3.1 0.0 0.0 0.5 2.6 0.6 1.8 1.6 1.8 0.0 4.9 0.0 1.4 4.4 0.5 0.5 0.0 1.1 1.4 0.0 0.1 57.2 4.9 0.0 0.0 0.3 1.1 0.2 10.2 0.3 1.8 1.9 0.0 2.6 4.1 4.0 2.1 0.6 0.0 4.9 1.7 2.0 0.0 0.5 1.9 2.0 0.0 2.6 3.0 2.1 1.3 2.8 3.0 0.7 2.9 0.2 0.0 5.1 MFSD2A "FLJ14490, MFSD2" ENSG00000168389 "Major facilitator superfamily domain containing 2A" Q8NA29 1 39955112-39969968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Symport, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 96.9;liver: 162.0;skin 1: 87.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 136.2;Hepatocytes: 299.6;Proximal enterocytes: 235.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 13.2;intermediate monocyte: 6.6;myeloid DC: 14.7;plasmacytoid DC: 24.3" "Group enriched" "Detected in many" 12 "dendritic cells: 24.3;monocytes: 13.2" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 52.0;THP-1: 169.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043107 Uncertain Approved "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Plasma membrane, Cytoplasmic bodies" "HPA043107: AB_10794387" "unprognostic (2.20e-1)" "unprognostic (1.15e-1)" "unprognostic (5.23e-3)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (6.92e-2)" "unprognostic (2.61e-2)" "unprognostic (2.45e-2)" "unprognostic (1.60e-1)" "unprognostic (4.33e-1)" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (9.26e-2)" "unprognostic (4.11e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.33e-4)" 6.3 1.4 34.0 3.4 31.7 8.4 13.4 34.8 36.0 4.8 22.2 7.2 14.6 8.5 96.9 12.5 3.5 2.3 1.4 30.9 33.4 5.8 162.0 36.1 2.3 38.5 33.8 2.2 0.6 0.7 8.0 17.1 38.6 2.4 5.0 2.6 4.0 79.2 0.5 87.8 32.0 3.5 32.8 1.5 1.9 33.9 37.2 1.6 7.5 0.1 3.6 20.2 14.1 33.1 6.2 2.7 12.5 18.9 8.7 1.6 0.0 5.9 11.2 12.8 15.1 0.8 3.4 38.0 3.4 3.0 8.8 15.0 12.4 21.8 9.8 4.9 6.0 4.6 0.1 0.1 28.8 6.8 21.8 9.7 13.3 52.0 21.5 2.3 3.1 11.5 0.0 9.5 5.7 0.8 10.6 10.4 10.1 21.4 4.7 7.4 18.5 8.7 2.1 17.9 4.4 6.7 4.5 31.7 3.0 1.1 1.5 169.8 2.0 2.7 5.3 9.5 24.9 1.8 3.5 8.5 28.9 26.0 9.2 0.0 13.2 1.4 0.1 6.6 0.2 1.5 0.1 0.2 14.7 0.2 0.0 0.1 0.7 0.2 1.2 24.3 0.0 3.6 34.0 31.7 34.8 36.0 30.9 33.4 38.5 33.8 38.6 32.8 37.2 33.1 0.5 19.2 136.2 3.3 6.3 52.8 21.2 40.0 51.2 2.0 6.3 2.3 0.6 12.8 30.8 16.5 0.0 0.5 5.7 62.2 0.0 3.4 1.0 25.8 5.5 22.9 1.2 5.7 1.5 24.8 7.6 9.7 24.5 61.8 17.2 0.1 7.1 299.6 6.7 0.0 1.3 34.5 12.2 9.8 43.3 2.7 0.6 16.1 0.0 38.4 5.5 38.8 0.0 0.0 1.6 27.2 39.3 0.4 5.0 13.9 235.1 6.1 33.9 2.7 0.0 5.0 3.3 1.0 1.3 49.3 54.8 52.5 3.3 0.1 20.7 26.6 MIB1 "DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6" ENSG00000101752 "Mindbomb E3 ubiquitin protein ligase 1" Q86YT6 18 21704957-21870953 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 121.2;Oligodendrocytes: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "REH: 121.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019100, CAB037044" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "CAB037044: AB_1841007, HPA019100: AB_1853934" "unprognostic (1.38e-1)" "unprognostic (6.92e-2)" "unprognostic (7.29e-2)" "unprognostic (6.99e-2)" "unprognostic (5.66e-2)" "unprognostic (3.23e-2)" "unprognostic (8.45e-3)" "unprognostic (2.70e-1)" "unprognostic (5.42e-2)" "unprognostic (4.69e-2)" "unprognostic (3.78e-2)" "unprognostic (4.70e-2)" "unprognostic (8.33e-3)" "unprognostic (4.91e-3)" "unprognostic (1.73e-1)" "unprognostic (4.86e-2)" "unprognostic (1.85e-2)" 8.1 6.3 9.1 6.0 9.1 4.9 11.2 9.2 8.5 11.0 8.0 7.1 5.1 13.0 9.5 8.0 7.1 8.6 6.0 8.4 9.2 11.1 10.4 7.2 7.6 9.5 10.2 11.7 8.1 9.8 5.2 11.0 8.6 10.1 7.0 8.3 8.4 8.5 5.8 9.1 5.2 10.2 10.1 7.2 7.6 8.7 10.3 11.5 13.6 7.0 7.9 8.4 8.2 9.6 19.9 7.6 36.4 25.8 19.5 23.0 9.0 15.6 17.2 10.8 15.6 11.3 7.1 16.9 14.1 21.4 11.8 13.2 21.4 21.0 24.4 22.4 10.4 18.8 9.7 15.9 15.8 38.3 7.8 14.8 23.0 12.6 32.0 16.0 27.8 6.6 26.5 47.5 17.2 9.5 18.9 14.7 9.5 12.2 10.2 121.1 30.3 42.5 18.7 16.9 12.1 30.1 26.8 12.4 13.9 18.6 8.8 25.1 23.9 27.8 14.2 11.7 21.1 25.6 9.5 25.4 11.8 24.1 16.9 0.7 0.3 0.1 0.2 0.1 0.2 0.2 0.3 0.2 0.1 0.1 0.2 0.1 0.3 0.5 0.1 0.2 0.4 0.1 9.1 9.1 9.2 8.5 8.4 9.2 9.5 10.2 8.6 10.1 10.3 9.6 35.7 48.1 22.7 68.2 11.9 21.9 15.1 19.8 24.5 28.8 24.1 19.7 18.1 25.8 31.8 16.5 25.0 13.3 18.2 20.8 3.9 13.4 7.0 29.0 59.2 30.8 24.0 23.1 106.7 12.9 7.5 33.1 10.2 32.4 14.5 16.8 24.3 30.0 12.9 15.2 92.6 17.1 26.4 17.2 16.2 5.6 20.5 14.2 26.6 67.5 19.4 17.7 15.5 121.2 109.6 18.8 7.0 24.8 18.1 48.5 8.7 15.9 30.6 14.5 0.0 35.4 26.9 26.2 12.0 23.4 24.6 25.3 14.5 21.8 10.4 25.3 MIEN1 "C17orf37, C35, MGC14832, ORB3, Rdx12, XTP4" ENSG00000141741 "Migration and invasion enhancer 1" Q9BRT3 17 39728496-39730532 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 14 "OE19: 1667.9;SK-BR-3: 502.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056650, HPA061344" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" Nucleoplasm "HPA056650: , HPA061344: AB_2684484" "unprognostic (2.48e-1)" "unprognostic (3.18e-2)" "unprognostic (3.04e-1)" "unprognostic (1.13e-2)" "unprognostic (3.04e-1)" "unprognostic (1.17e-1)" "unprognostic (4.47e-2)" "unprognostic (8.37e-2)" "unprognostic (6.72e-2)" "unprognostic (2.03e-1)" "unprognostic (1.90e-1)" "unprognostic (3.17e-1)" "unprognostic (2.99e-2)" "unprognostic (3.70e-1)" "unprognostic (2.00e-1)" "unprognostic (3.88e-3)" "unprognostic (2.22e-3)" 29.1 35.9 33.4 17.5 35.4 27.0 31.5 36.2 44.8 31.1 34.2 42.4 26.3 29.0 14.6 47.3 27.2 12.1 49.5 32.5 35.3 57.2 53.7 29.6 20.2 34.5 34.8 18.5 40.7 21.6 39.6 13.5 34.5 46.3 12.8 4.8 46.2 13.8 47.2 35.0 37.5 9.5 32.9 36.2 48.5 41.3 35.4 13.9 37.0 5.3 13.7 31.0 32.0 37.2 38.8 59.7 13.4 34.5 16.3 12.0 16.2 40.7 21.4 24.2 23.6 12.9 27.2 28.1 55.5 15.1 39.0 47.1 15.6 13.8 8.2 58.2 65.8 26.5 29.8 36.5 28.2 33.9 39.2 10.8 23.3 11.7 12.0 18.8 15.6 52.9 38.2 48.9 14.7 22.5 70.1 38.2 12.5 1667.9 26.4 32.2 23.6 56.8 12.2 21.8 43.6 41.7 40.8 502.3 70.7 12.0 66.1 48.1 41.5 16.4 41.8 78.9 47.1 62.3 62.8 55.1 64.5 41.1 32.4 138.5 76.2 107.3 80.1 100.9 43.4 109.2 56.2 72.3 54.5 88.3 43.9 63.1 132.9 58.7 104.2 79.4 94.6 119.9 33.4 35.4 36.2 44.8 32.5 35.3 34.5 34.8 34.5 32.9 35.4 37.2 59.8 44.8 64.2 7.8 60.9 60.2 138.1 185.1 95.6 25.7 127.0 114.2 59.6 82.9 129.3 99.3 4.2 150.2 69.1 226.6 303.3 137.0 136.2 81.6 48.7 58.9 188.8 72.0 11.0 176.1 74.4 50.9 76.5 77.3 81.8 43.8 54.7 118.9 148.0 35.3 9.6 178.3 254.3 101.3 42.8 76.7 42.3 81.3 138.7 12.2 80.1 90.7 130.7 4.5 20.8 216.8 283.7 49.7 54.0 194.8 188.5 224.9 122.1 17.3 46.0 31.5 61.1 108.5 68.0 131.7 70.3 266.1 65.4 51.7 128.1 204.0 MLKL FLJ34389 ENSG00000168404 "Mixed lineage kinase domain like pseudokinase" Q8NB16 16 74671855-74700960 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 32.1;Endothelial cells: 25.9;granulocytes: 29.1;Macrophages: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078638 Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions, Cytosol" "HPA078638: " "unprognostic (7.53e-2)" "unprognostic (1.74e-2)" "unprognostic (2.57e-1)" "prognostic favorable (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (5.69e-2)" "unprognostic (3.67e-3)" "unprognostic (1.90e-1)" "unprognostic (6.64e-3)" "unprognostic (1.37e-1)" "unprognostic (2.74e-1)" "unprognostic (1.60e-3)" "unprognostic (5.30e-2)" "unprognostic (1.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.53e-3)" 20.0 7.1 8.4 20.3 8.7 30.7 12.1 8.6 12.7 9.0 9.6 11.0 11.0 6.0 2.0 15.6 8.0 11.5 10.6 7.8 8.2 15.4 9.3 25.6 15.4 10.1 9.8 3.0 9.9 1.6 3.7 9.2 9.3 8.4 11.4 0.3 13.3 4.3 3.1 4.9 14.4 7.6 9.1 36.1 10.8 1.2 10.3 6.7 8.7 3.1 13.8 12.3 11.5 9.6 13.5 24.4 0.1 0.1 6.0 12.4 0.2 17.0 14.8 15.4 22.4 13.9 26.6 0.3 19.1 14.2 13.7 21.7 4.3 24.9 5.8 8.3 0.6 18.8 17.6 16.2 4.2 12.3 18.6 8.5 2.4 16.8 5.7 9.0 37.3 21.3 2.7 2.5 11.9 22.0 7.0 24.3 2.2 29.3 30.0 13.5 1.8 23.8 22.0 10.2 1.0 0.8 13.4 8.7 7.2 0.1 6.2 12.5 41.4 7.8 4.8 7.0 11.7 11.2 40.2 3.2 13.7 42.3 3.9 21.9 36.2 45.8 11.2 22.2 15.4 8.1 12.6 12.0 18.9 6.7 6.8 10.4 48.6 3.6 23.3 1.2 17.4 16.0 8.4 8.7 8.6 12.7 7.8 8.2 10.1 9.8 9.3 9.1 10.3 9.6 32.1 3.2 10.7 1.0 9.8 3.4 6.8 3.1 7.4 0.2 3.3 3.4 3.1 2.8 5.5 1.8 0.0 0.2 9.6 8.9 1.9 4.6 3.5 1.2 1.9 25.9 1.2 3.4 0.5 5.2 0.8 7.1 15.3 1.6 29.1 0.3 16.8 1.3 16.6 1.7 0.5 10.9 0.0 18.2 7.8 5.2 0.9 28.9 7.2 11.2 16.7 0.1 11.3 1.5 5.2 4.9 9.4 0.4 18.5 2.8 5.5 0.6 2.0 0.6 0.0 3.0 3.1 0.1 0.2 13.4 2.8 0.3 16.5 0.2 9.5 7.5 MLNR GPR38 ENSG00000102539 "Motilin receptor" O43193 13 49220338-49222377 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.3;thyroid gland: 1.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "testis cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.3;THP-1: 4.0" "Not detected" "Not detected" HPA070324 Approved "Plasma membrane,Cytosol" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 43: THP-1 - Innate immune response" "Plasma membrane, Cytosol" "HPA070324: " "unprognostic (9.75e-2)" "unprognostic (2.13e-2)" "unprognostic (2.90e-1)" "unprognostic (1.13e-1)" "unprognostic (6.03e-2)" "unprognostic (7.80e-2)" "unprognostic (1.54e-2)" "unprognostic (7.79e-2)" "unprognostic (1.88e-2)" "unprognostic (3.74e-1)" "unprognostic (2.61e-4)" "unprognostic (3.53e-2)" "unprognostic (1.04e-1)" "unprognostic (1.38e-1)" 0.0 0.0 0.1 0.0 0.3 1.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.1 0.4 0.1 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.3 0.3 0.4 0.3 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MMP25 "MMP20, MMPL1, MT6-MMP" ENSG00000008516 "Matrix metallopeptidase 25" Q9NPA2 16 3046062-3060726 "Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.1;lymphoid tissue: 81.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 6.7;Langerhans cells: 5.8;monocytes: 15.0" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.1" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "basophil: 18.3;neutrophil: 20.3" "Lineage enriched" "Detected in single" 39 "granulocytes: 20.3" "Cell line enriched" "Detected in some" 15 "HMC-1: 102.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025177, HPA055640" Uncertain Supported "Plasma membrane" "Secreted to blood" NA NA 120000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "CAB025177: , HPA055640: " "unprognostic (4.51e-3)" "unprognostic (9.28e-3)" "unprognostic (7.57e-2)" "unprognostic (2.95e-3)" "unprognostic (2.26e-1)" "prognostic favorable (1.09e-5)" "unprognostic (1.36e-1)" "unprognostic (7.39e-3)" "unprognostic (7.63e-3)" "unprognostic (2.29e-2)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (2.37e-3)" "unprognostic (1.17e-2)" "unprognostic (8.30e-2)" "unprognostic (4.01e-1)" "unprognostic (2.02e-1)" 5.8 0.4 0.5 15.1 0.4 33.1 1.4 0.3 1.6 0.7 0.6 1.7 1.1 0.5 0.1 1.3 6.2 1.1 2.4 0.3 0.3 1.4 2.9 14.4 2.6 0.6 0.5 0.4 1.2 0.2 0.8 1.0 0.6 1.0 1.4 0.0 1.2 0.1 0.5 0.7 3.5 0.9 0.3 81.8 1.9 0.4 0.7 1.4 1.2 3.5 1.9 2.2 0.9 0.3 0.0 0.0 1.2 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.7 0.1 0.0 6.7 0.5 0.0 0.0 0.0 0.0 0.2 102.2 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.7 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.3 7.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 1.1 0.1 18.3 0.2 4.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 20.3 0.5 0.0 0.4 0.2 0.0 0.5 0.4 0.3 1.6 0.3 0.3 0.6 0.5 0.6 0.3 0.7 0.3 1.0 3.2 6.7 0.0 0.7 0.4 0.4 0.2 0.0 0.8 2.0 1.3 1.0 0.0 0.8 1.8 0.0 0.0 1.8 0.2 0.0 0.4 0.0 1.2 1.2 1.0 0.0 2.7 1.6 0.6 0.2 0.6 1.1 3.8 1.3 0.2 0.0 0.3 0.1 0.0 1.9 0.2 0.0 3.5 5.8 0.0 0.0 3.3 0.0 1.0 15.0 0.3 3.1 1.5 0.5 1.3 0.0 0.7 0.8 0.4 1.2 0.2 0.1 0.0 0.0 0.7 0.9 0.1 0.2 0.6 0.3 0.0 4.0 0.1 0.3 0.3 MPL "CD110, THPOR, TPOR" ENSG00000117400 "MPL proto-oncogene, thrombopoietin receptor" P40238 1 43337818-43354466 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Erythroid cells: 3.0;Excitatory neurons: 2.0;Oligodendrocytes: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enriched" "Detected in some" 57 "HEL: 77.4" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Low region specificity" "Detected in many" HPA007619 Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Nuclear membrane" "HPA007619: AB_1854080" "unprognostic (2.74e-1)" "unprognostic (6.56e-2)" "unprognostic (2.95e-1)" "unprognostic (8.71e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-3)" "unprognostic (1.19e-1)" "unprognostic (1.22e-2)" "unprognostic (5.83e-2)" "unprognostic (1.03e-1)" "unprognostic (5.94e-4)" "unprognostic (1.51e-1)" "unprognostic (1.19e-4)" "unprognostic (2.39e-1)" "unprognostic (3.26e-1)" "unprognostic (1.03e-4)" "unprognostic (1.42e-1)" 0.6 0.4 0.8 0.2 1.7 1.8 0.4 0.8 1.3 0.3 0.1 0.3 0.3 0.7 1.2 0.5 0.8 0.3 1.0 0.6 1.2 0.4 0.4 0.6 0.2 1.2 1.0 2.9 0.8 0.4 0.0 0.3 1.1 0.9 0.4 1.5 0.4 0.7 0.6 0.5 0.2 0.7 0.7 0.4 0.5 1.2 1.1 0.1 0.9 0.3 0.1 0.2 0.0 2.8 0.4 0.7 0.1 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 1.3 0.1 0.3 0.1 0.0 0.6 0.0 0.2 0.0 0.4 0.1 77.4 1.2 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.2 0.5 0.1 0.1 0.2 0.0 0.2 0.7 0.6 0.4 0.2 0.6 0.1 0.2 0.2 0.3 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.2 1.4 0.1 0.1 0.3 0.1 1.8 0.8 1.7 0.8 1.3 0.6 1.2 1.2 1.0 1.1 0.7 1.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MPP1 "DXS552E, PEMP" ENSG00000130830 "Membrane palmitoylated protein 1" Q00013 X 154778684-154821007 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 116.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 410.9;Erythroid cells: 393.8;Hofbauer cells: 291.9;Macrophages: 155.9;Syncytiotrophoblasts: 454.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 215.7;neutrophil: 202.1" "Group enriched" "Detected in all" 8 "dendritic cells: 57.7;granulocytes: 215.7;monocytes: 98.8" "Cell line enhanced" "Detected in many" "HEL: 218.0;REH: 136.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076675 Enhanced Supported "Plasma membrane,Centriolar satellite" NA NA 650000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Centriolar satellite" "HPA076675: " "unprognostic (2.15e-1)" "unprognostic (4.06e-2)" "unprognostic (4.52e-2)" "unprognostic (1.83e-3)" "unprognostic (7.14e-2)" "unprognostic (2.60e-2)" "unprognostic (7.47e-2)" "unprognostic (1.54e-1)" "unprognostic (1.82e-1)" "unprognostic (7.79e-2)" "unprognostic (3.77e-3)" "unprognostic (1.70e-3)" "prognostic favorable (4.60e-6)" "unprognostic (6.69e-2)" "unprognostic (2.53e-2)" "unprognostic (4.68e-2)" "unprognostic (6.67e-3)" 24.1 27.2 21.0 27.1 22.0 116.8 16.5 26.2 29.7 11.6 18.6 17.2 59.4 13.4 5.3 10.5 15.7 24.3 26.0 22.5 25.2 42.9 37.5 28.3 24.9 28.3 21.9 10.6 34.6 30.7 9.7 86.5 30.7 15.5 17.6 10.6 23.7 18.1 29.2 10.2 47.3 19.7 22.5 40.9 11.8 7.1 27.3 72.8 14.0 27.2 12.5 21.3 10.0 28.2 41.4 8.3 18.7 18.7 19.0 20.1 59.5 15.3 23.3 25.3 30.8 23.7 3.7 32.8 29.3 17.1 67.9 4.6 21.6 6.9 19.9 34.9 38.0 218.0 5.7 25.3 28.6 44.4 121.4 19.4 9.0 28.2 7.0 25.9 58.5 42.1 96.1 5.3 28.7 0.2 102.6 60.3 1.9 3.8 28.2 136.0 4.8 15.5 14.8 3.3 4.7 7.5 12.7 1.2 13.3 18.5 3.2 25.8 26.6 23.2 12.5 51.8 41.7 36.6 52.9 12.5 32.7 61.7 11.1 49.7 95.6 215.7 5.1 76.6 6.0 7.8 5.9 5.7 57.7 2.7 15.4 7.9 202.1 10.1 98.8 15.5 3.5 79.1 21.0 22.0 26.2 29.7 22.5 25.2 28.3 21.9 30.7 22.5 27.3 28.2 18.3 3.2 11.2 8.1 6.3 8.7 4.8 0.2 8.0 10.2 7.1 5.1 17.0 41.5 6.2 7.3 4.2 410.9 6.9 16.3 21.5 11.7 0.6 3.5 5.7 18.9 11.5 393.8 16.1 2.8 27.0 11.4 1.1 6.4 90.6 9.6 11.7 10.6 291.9 16.8 17.1 4.4 0.0 104.7 30.2 2.4 8.7 155.9 10.6 15.9 52.5 15.4 9.2 6.0 5.9 3.7 4.1 13.2 8.1 3.1 57.4 66.3 2.2 8.2 0.0 8.6 10.3 0.7 6.8 6.4 6.0 454.4 9.9 14.5 5.8 1.2 MPZL1 "FLJ21047, PZR" ENSG00000197965 "Myelin protein zero like 1" O95297 1 167721192-167791919 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 183.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 183.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026966, HPA063538" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA026966: AB_10600931, HPA063538: AB_2685034" "unprognostic (6.54e-2)" "unprognostic (9.26e-3)" "unprognostic (4.59e-2)" "unprognostic (4.88e-1)" "unprognostic (2.18e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (4.27e-6)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.22e-1)" "unprognostic (3.41e-2)" "unprognostic (2.59e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (3.99e-7)" "unprognostic (3.55e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (8.08e-4)" "unprognostic (4.21e-2)" 74.8 34.1 23.1 49.2 21.6 8.3 91.6 22.0 21.8 63.1 40.1 60.1 40.8 50.0 27.4 52.9 60.1 67.7 52.4 22.1 28.3 28.6 23.0 42.3 35.2 25.7 30.0 46.4 27.5 28.4 33.0 68.9 30.7 41.8 59.4 12.7 73.1 38.9 14.7 34.0 41.0 62.6 26.4 29.2 43.8 48.2 28.6 29.3 39.5 26.8 45.9 74.7 51.3 24.9 88.5 126.3 96.9 75.8 303.4 137.2 304.8 134.5 172.7 86.3 106.4 234.4 119.5 31.0 152.9 171.6 76.1 144.2 97.5 149.0 72.6 70.9 52.8 25.5 63.5 56.7 188.5 30.2 16.1 126.1 183.5 137.8 153.4 121.4 116.4 93.6 97.1 63.5 103.0 29.3 103.6 36.2 61.9 176.7 53.5 62.5 82.7 137.5 131.4 84.6 55.7 91.8 119.6 122.4 69.7 221.9 66.6 16.0 132.8 97.9 44.1 127.5 73.8 94.0 157.2 142.8 140.8 35.3 15.8 7.7 29.1 20.0 2.8 24.8 1.3 14.7 2.8 4.1 38.5 8.8 7.7 2.6 183.8 10.4 34.6 43.9 0.5 11.0 23.1 21.6 22.0 21.8 22.1 28.3 25.7 30.0 30.7 26.4 28.6 24.9 52.9 28.9 30.0 31.0 15.1 76.3 78.5 57.6 35.9 8.8 75.9 73.9 6.3 20.0 49.6 20.2 6.2 128.7 21.1 67.1 5.9 63.2 1.8 14.5 40.4 56.7 47.8 10.1 32.8 75.6 145.2 118.2 41.3 23.0 3.8 75.3 24.3 23.3 37.7 10.1 27.9 39.7 20.3 28.2 31.9 4.9 69.9 23.5 16.0 60.0 84.0 11.8 3.1 141.8 1.7 81.0 41.6 83.8 23.5 141.7 55.5 10.1 28.3 13.9 19.7 18.6 48.6 8.9 26.8 41.2 55.5 76.9 8.6 49.4 61.0 57.7 MR1 HLALS ENSG00000153029 "Major histocompatibility complex, class I-related" Q95460 1 181033425-181061938 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA048304 Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA048304: AB_2680347" "unprognostic (6.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.31e-2)" "unprognostic (1.96e-1)" "unprognostic (8.66e-3)" "unprognostic (4.37e-2)" "unprognostic (1.96e-1)" "unprognostic (1.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.18e-1)" "unprognostic (3.49e-2)" "unprognostic (6.41e-2)" "unprognostic (1.05e-2)" "unprognostic (7.40e-3)" "unprognostic (4.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.07e-2)" 8.6 9.6 3.2 14.2 3.3 11.1 9.7 2.2 3.5 10.2 5.8 6.7 7.4 9.5 9.6 9.6 10.4 12.7 6.2 3.1 3.8 9.9 10.6 18.0 14.6 4.7 3.3 13.6 3.7 14.0 8.9 13.5 3.7 10.9 8.1 1.5 5.9 10.5 2.1 8.7 6.9 12.5 3.8 12.3 8.7 2.6 4.4 20.2 16.7 3.8 15.2 16.3 7.4 4.8 7.9 5.4 0.1 4.6 32.2 38.8 13.9 15.5 42.2 12.7 21.5 2.2 31.9 9.7 31.6 28.1 9.9 20.5 0.7 18.3 11.1 29.6 5.2 14.2 5.6 9.8 10.8 11.5 40.6 25.2 49.6 18.9 20.3 23.7 1.3 17.8 26.7 25.6 24.9 8.8 12.1 8.3 0.1 0.1 0.8 13.7 0.3 27.3 13.9 23.1 0.2 0.3 8.2 14.8 10.9 6.0 15.4 24.6 8.1 12.5 1.7 21.8 7.7 42.2 15.3 17.9 11.7 14.7 1.2 32.6 21.8 22.9 16.3 27.4 14.6 14.3 14.6 14.6 18.8 18.3 10.8 16.2 14.7 19.0 23.6 10.2 17.0 15.2 3.2 3.3 2.2 3.5 3.1 3.8 4.7 3.3 3.7 3.8 4.4 4.8 4.4 19.2 32.4 8.8 14.7 5.0 8.3 32.6 12.0 0.8 7.7 6.1 4.1 8.6 20.9 14.7 0.0 17.5 15.9 1.6 5.9 10.8 0.3 5.9 12.1 4.9 2.4 11.4 3.1 6.4 9.5 12.8 2.6 7.3 17.1 13.5 3.6 8.9 25.8 0.0 1.7 2.7 32.6 25.2 9.1 0.4 10.8 25.3 7.2 11.2 30.8 4.1 26.8 0.0 0.5 7.5 4.5 12.0 9.1 7.4 2.2 2.4 15.3 0.6 0.0 8.6 9.2 0.4 1.6 10.9 5.4 24.5 15.7 22.4 3.5 13.4 MRGPRF "GPR140, GPR168, MGC21621, mrgF" ENSG00000172935 "MAS related GPR family member F" Q96AM1 11 69004395-69013382 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 171.2;intestine: 159.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 33.3;Leydig cells: 66.2;Peritubular cells: 100.8;Sertoli cells: 52.6;Smooth muscle cells: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 67.6;ASC TERT1: 30.0;BJ: 39.5;BJ hTERT+: 99.1;BJ hTERT+ SV40 Large T+: 36.8;fHDF/TERT166: 30.8;U-2197: 46.8" "Region enriched" "Detected in many" 5 "cerebellum: 14.8" "Region enhanced" "Detected in some" "spinal cord: 4.8" HPA028811 Approved Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear membrane, Plasma membrane" "HPA028811: AB_10603875" "unprognostic (2.49e-2)" "unprognostic (3.89e-2)" "unprognostic (1.20e-1)" "unprognostic (9.03e-2)" "unprognostic (5.16e-2)" "unprognostic (6.52e-3)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.00e-1)" "unprognostic (1.36e-1)" "unprognostic (8.32e-2)" "unprognostic (1.47e-1)" "unprognostic (4.55e-7)" "unprognostic (2.75e-2)" "unprognostic (2.27e-1)" "unprognostic (2.86e-2)" "unprognostic (3.62e-3)" 41.7 3.8 2.6 12.8 2.9 0.0 32.5 12.0 3.9 103.6 5.5 159.2 9.3 171.2 14.2 16.2 98.0 16.7 13.7 2.4 3.1 17.1 7.0 18.7 4.5 4.7 2.8 37.0 3.4 0.5 4.1 11.6 3.3 48.3 8.9 0.2 10.8 45.6 5.1 15.2 38.3 59.3 2.8 13.4 44.1 7.3 2.8 0.7 10.7 3.0 1.3 75.2 65.6 2.5 0.0 0.1 0.1 0.0 67.6 30.0 1.4 39.5 99.1 36.8 24.3 0.0 1.8 0.0 0.8 30.8 0.1 0.1 0.1 0.0 6.8 0.0 0.0 0.0 2.8 0.0 8.5 0.0 0.0 22.1 0.0 23.5 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 2.9 1.5 0.8 0.1 0.0 3.4 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 2.5 0.0 0.0 0.0 22.4 0.0 46.8 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.9 12.0 3.9 2.4 3.1 4.7 2.8 3.3 2.8 2.8 2.5 3.2 0.0 0.0 0.0 0.6 5.0 0.2 0.0 1.2 0.0 0.3 2.3 0.6 2.8 0.0 11.0 0.0 0.7 0.1 0.0 0.0 0.0 4.9 1.1 20.6 2.3 0.0 0.0 1.1 0.0 0.6 33.3 0.5 0.8 0.0 0.0 3.9 3.8 1.1 0.0 0.2 0.0 0.0 0.0 7.3 7.9 66.2 0.2 7.2 3.7 0.0 3.0 0.0 0.0 0.2 0.1 0.0 100.8 0.1 0.3 0.0 0.9 0.0 0.3 52.6 19.1 63.7 1.3 0.5 0.4 3.8 1.1 0.6 0.6 0.0 0.4 MS4A1 "B1, Bp35, CD20, MS4A2" ENSG00000156738 "Membrane spanning 4-domains A1" P11836 11 60455846-60470752 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "B-cell activation" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 673.3" "Cell type enriched" "Detected in some" 35 "B-cells: 970.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 96 "memory B-cell: 625.4;naive B-cell: 627.0" "Lineage enriched" "Detected in many" 96 "B-cells: 627.0" "Group enriched" "Detected in some" 26 "Daudi: 731.3;U-698: 364.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000015, HPA014341, HPA014391" Enhanced Supported "Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "CAB000015: AB_2282030, HPA014341: AB_1846265, HPA014391: AB_1846264" "prognostic favorable (4.34e-5)" "unprognostic (4.45e-4)" "unprognostic (1.19e-4)" "unprognostic (2.04e-3)" "unprognostic (1.06e-1)" "unprognostic (5.53e-7)" "unprognostic (2.46e-3)" "unprognostic (1.85e-3)" "unprognostic (3.06e-2)" "unprognostic (2.89e-4)" "unprognostic (6.96e-2)" "unprognostic (2.84e-2)" "unprognostic (3.96e-5)" "unprognostic (2.23e-1)" "unprognostic (8.04e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-1)" 3.6 0.4 0.0 149.7 0.0 19.1 0.8 0.0 0.1 0.5 0.1 9.0 3.0 2.2 1.0 4.2 0.5 8.4 1.8 0.0 0.1 3.4 2.1 4.0 500.4 0.2 0.0 0.3 0.2 7.3 0.3 0.9 0.1 5.1 10.6 0.0 8.9 0.3 0.8 0.1 123.5 1.2 0.1 253.8 18.4 1.2 0.1 50.6 6.7 0.1 673.3 16.3 1.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 731.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.5 0.2 0.0 0.1 0.0 364.1 0.0 0.2 0.0 0.8 0.5 0.3 2.4 0.1 3.7 625.4 2.8 5.5 0.5 627.0 0.5 2.1 2.0 6.5 0.6 0.5 0.8 32.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.3 0.0 3.8 0.0 970.5 0.1 0.1 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.0 14.5 0.3 0.0 0.0 4.5 0.7 0.1 0.3 0.0 7.0 0.0 0.0 0.1 1.8 2.0 0.1 2.5 0.0 1.1 0.3 0.1 0.0 0.0 0.2 0.0 0.6 0.3 2.0 0.0 4.6 7.2 0.0 2.5 0.0 2.1 0.0 0.0 0.0 0.3 0.0 9.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.5 0.2 0.1 0.8 0.1 0.0 27.3 0.7 0.2 0.0 MTM1 ENSG00000171100 "Myotubularin 1" Q13496 X 150568621-150673143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 52.2;Oligodendrocytes: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010008, HPA010665" Approved Supported "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA010008: AB_1079426, HPA010665: AB_1079425" "unprognostic (3.66e-3)" "unprognostic (8.43e-3)" "unprognostic (3.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.08e-1)" "unprognostic (6.45e-2)" "unprognostic (4.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.74e-1)" "unprognostic (2.35e-2)" "unprognostic (1.08e-1)" "unprognostic (4.59e-2)" "prognostic favorable (7.40e-7)" "unprognostic (4.46e-2)" "unprognostic (1.25e-1)" "unprognostic (4.99e-2)" "unprognostic (2.46e-1)" 6.8 11.1 7.4 9.7 8.3 11.3 7.6 8.0 8.4 5.7 6.1 19.8 11.7 6.5 8.4 7.5 9.6 7.1 7.3 6.9 8.5 12.9 18.4 11.2 12.4 7.8 8.6 11.7 4.9 16.0 3.8 6.3 8.0 8.0 19.2 5.4 6.3 10.7 11.8 8.2 12.1 6.9 7.7 11.9 7.8 11.5 8.8 8.4 11.2 10.1 9.7 7.1 4.7 8.8 14.3 6.1 8.5 3.1 7.5 7.3 5.4 6.1 8.5 7.0 7.9 4.7 7.3 22.2 11.4 8.3 21.9 9.9 6.1 11.5 8.6 6.4 5.2 5.6 5.4 15.0 5.8 25.2 19.1 4.5 14.3 5.7 11.9 6.9 9.4 9.3 3.9 19.8 8.8 4.5 6.9 25.2 4.3 13.4 7.4 8.0 4.9 4.5 11.7 6.9 2.2 2.4 5.5 11.3 8.5 11.9 4.1 35.2 8.2 5.0 3.1 12.4 7.1 4.2 10.0 20.3 6.0 14.8 8.0 34.8 9.5 27.9 2.0 10.8 6.8 8.0 9.6 7.3 12.0 10.6 9.0 5.4 11.6 14.6 9.8 7.4 12.2 7.1 7.4 8.3 8.0 8.4 6.9 8.5 7.8 8.6 8.0 7.7 8.8 8.8 9.9 9.6 20.0 52.2 13.9 15.2 8.3 5.8 2.2 0.0 5.8 3.9 15.0 4.3 6.0 3.7 0.0 2.1 8.4 33.0 1.9 3.4 35.6 7.7 5.0 11.5 9.6 7.4 44.0 4.3 2.8 6.6 8.2 4.8 8.8 3.3 16.4 13.2 8.0 0.0 41.5 17.7 2.0 16.3 10.4 18.8 6.2 13.0 5.4 24.4 12.0 0.0 0.0 27.6 47.7 4.7 9.5 12.8 8.0 6.8 11.2 14.7 13.4 0.0 0.0 5.2 6.9 5.1 4.1 4.9 19.0 7.3 12.8 4.8 13.8 9.7 MUC1 "ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 485.8;stomach 1: 1064.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1370.0;Collecting duct cells: 491.1;Exocrine glandular cells: 1164.9;Gastric mucus-secreting cells: 640.6;Pancreatic endocrine cells: 1074.8;Respiratory ciliated cells: 555.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Group enriched" "Detected in many" 6 "CAPAN-2: 1146.1;OE19: 548.3;RPTEC TERT1: 870.2;T-47d: 383.6" "Not detected" "Not detected" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA 4000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" 15.2 6.3 5.3 21.9 5.7 9.4 78.2 4.7 8.6 194.2 4.7 176.0 21.4 40.2 61.6 209.9 120.0 125.8 6.8 5.1 5.7 485.8 3.9 321.5 1.8 7.8 6.3 9.8 358.5 1.0 14.1 3.3 6.0 43.9 103.6 1.3 135.0 34.4 1.9 20.6 35.2 20.0 6.1 5.4 1064.7 47.9 6.8 1.2 54.8 0.7 18.8 102.0 50.0 5.2 15.3 8.2 5.1 4.8 3.9 4.2 1.7 5.6 12.2 6.2 15.2 0.2 1146.1 0.0 81.9 9.5 2.7 23.2 1.0 0.3 1.8 10.4 0.8 1.8 101.5 0.0 2.4 0.4 36.1 9.5 2.1 2.8 2.2 12.7 2.1 1.9 9.2 15.4 4.3 120.0 1.6 1.2 3.5 548.3 2.1 2.3 0.6 29.3 870.2 0.9 5.1 2.1 28.0 48.3 1.5 4.1 383.6 5.6 2.2 3.9 6.7 10.5 1.2 17.7 9.8 0.2 5.9 1.1 1.4 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.1 5.3 5.7 4.7 8.6 5.1 5.7 7.8 6.3 6.0 6.1 6.8 5.2 2.3 432.7 1370.0 5.9 6.4 0.6 18.5 126.4 0.0 1.3 219.2 48.5 0.4 327.5 374.9 491.1 4.2 0.5 1.5 271.8 35.2 177.3 32.7 245.2 28.8 8.0 30.6 1.3 0.3 1164.9 1.1 7.0 640.6 282.8 48.0 0.3 1.8 0.9 0.2 1.7 0.3 351.5 164.8 2.2 1.0 81.0 2.5 7.2 5.4 1.0 24.3 1.7 0.0 0.5 0.1 1074.8 60.5 1.5 1.3 16.3 6.8 1.3 555.3 0.2 0.0 2.0 22.0 5.8 0.8 3.5 1.1 0.3 10.3 0.1 220.8 154.5 MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 1700.3;smooth muscle: 2137.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 728.5;Hepatocytes: 208.7;Peritubular cells: 690.5;Sertoli cells: 276.1;Smooth muscle cells: 448.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 200.0;BJ hTERT+: 298.2;fHDF/TERT166: 260.2;hTERT-RPE1: 202.7;RPTEC TERT1: 291.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" NA NA 1500000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: AB_2732543" "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.46e-4)" 143.6 57.4 37.6 188.7 64.8 3.3 163.4 72.1 42.4 281.3 14.1 551.5 110.9 669.2 232.9 420.6 289.8 250.4 33.6 33.6 46.7 64.4 67.2 85.2 33.6 104.6 64.8 95.9 15.3 11.6 2.6 70.2 99.3 907.6 299.1 13.6 140.1 1700.3 10.0 20.1 125.1 2137.7 55.6 89.5 122.7 50.5 52.2 8.0 22.2 14.9 19.1 505.7 84.8 112.1 14.4 38.4 10.8 7.8 10.8 1.9 4.7 200.0 298.2 137.3 92.1 8.1 7.4 0.6 42.5 260.2 67.0 4.8 5.2 1.8 149.0 0.2 0.7 102.4 0.9 28.9 56.1 0.6 9.8 36.9 3.5 24.4 34.4 202.7 8.9 1.3 1.2 0.5 90.9 1.7 0.2 2.5 12.0 0.5 5.1 13.5 6.8 36.7 291.9 8.5 1.4 6.4 21.8 1.9 3.1 25.0 1.0 0.3 33.4 39.5 13.9 10.3 30.7 3.4 4.2 0.3 104.0 1.0 9.6 7.4 1.6 0.4 0.1 0.2 0.0 0.2 0.0 0.0 3.5 0.1 0.2 0.1 5.0 0.0 0.0 3.3 0.2 20.9 37.6 64.8 72.1 42.4 33.6 46.7 104.6 64.8 99.3 55.6 52.2 112.1 45.9 16.0 38.3 43.4 2.5 20.5 27.2 24.8 1.2 2.9 19.9 728.5 25.2 37.1 5.7 27.6 125.1 0.8 3.5 88.1 3.9 6.0 40.7 45.9 46.6 56.9 11.4 3.2 25.2 3.9 0.8 40.1 3.1 54.4 2.5 3.2 45.3 208.7 4.9 3.3 3.4 3.9 8.2 7.9 37.0 33.8 104.7 20.8 19.6 8.4 1.2 4.7 0.0 5.5 37.0 4.0 18.7 690.5 3.3 8.6 14.2 17.2 17.6 19.9 276.1 5.6 448.7 4.7 4.6 1.3 20.2 2.5 3.2 4.5 4.2 3.7 MYO10 KIAA0799 ENSG00000145555 "Myosin X" Q9HD67 5 16661907-16936288 "Plasma proteins, Predicted intracellular proteins" Transport "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 189.5;Muller glia cells: 233.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "non-classical monocyte: 2.5" "Lineage enriched" "Detected in single" 5 "monocytes: 2.5" "Cell line enhanced" "Detected in many" "HeLa: 182.1;SK-MEL-30: 205.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015224, HPA024223" Enhanced Supported "Nucleoli rim,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoli rim" "CAB015224: , HPA024223: AB_1854248" "unprognostic (1.13e-2)" "prognostic unfavorable (4.35e-4)" "unprognostic (7.63e-2)" "unprognostic (1.04e-1)" "unprognostic (4.43e-2)" "unprognostic (2.96e-2)" "unprognostic (4.40e-2)" "unprognostic (8.34e-2)" "unprognostic (2.51e-2)" "unprognostic (3.16e-2)" "unprognostic (8.42e-2)" "unprognostic (1.85e-1)" "prognostic favorable (2.75e-4)" "unprognostic (8.93e-2)" "unprognostic (9.86e-2)" "unprognostic (4.56e-2)" "unprognostic (1.84e-1)" 13.8 3.0 47.4 6.2 46.3 3.2 7.9 24.6 41.1 6.7 55.1 19.3 22.8 6.2 3.5 9.3 4.3 8.4 4.5 39.8 24.8 14.7 7.7 19.0 1.3 32.6 30.9 15.8 32.2 10.7 9.5 31.5 27.6 5.8 19.1 15.1 11.0 5.0 8.2 15.6 19.5 4.9 27.3 13.9 32.0 15.6 46.4 4.9 37.5 4.4 2.0 11.1 7.8 45.7 68.2 108.3 31.3 14.9 24.7 17.0 35.1 117.2 89.2 35.5 27.4 63.1 10.2 1.5 78.9 52.9 42.3 33.4 139.1 73.7 57.1 0.2 16.7 0.1 182.1 13.7 81.5 0.4 1.5 30.9 26.8 78.5 92.1 57.4 110.5 0.2 0.2 4.8 28.7 10.5 0.2 0.4 80.5 56.6 37.2 26.1 10.3 66.9 22.0 49.6 5.2 2.8 27.0 11.4 205.0 53.2 8.1 9.1 137.8 77.6 23.6 0.7 61.1 0.7 0.5 0.5 38.3 11.2 76.2 0.5 0.2 0.2 0.1 0.5 0.1 0.1 0.1 0.1 0.2 0.3 0.2 0.2 0.3 0.1 2.5 0.1 0.1 0.1 47.4 46.3 24.6 41.1 39.8 24.8 32.6 30.9 27.6 27.3 46.4 45.7 53.5 35.3 34.6 158.7 1.4 40.9 31.0 23.0 29.6 11.0 18.6 11.6 3.8 55.8 26.3 31.3 18.8 20.4 0.3 46.4 17.6 110.8 30.2 118.5 20.8 61.3 74.0 0.0 3.9 40.6 63.4 13.7 68.3 116.0 27.8 189.5 77.1 1.7 5.6 82.4 5.4 53.2 20.3 7.1 4.8 9.5 12.8 5.7 67.6 87.1 3.8 233.8 0.0 103.5 23.5 114.7 50.3 19.2 0.4 42.6 28.3 4.2 18.8 9.2 65.7 8.2 31.5 3.8 12.2 30.7 31.8 147.8 2.4 4.1 66.9 38.6 MYO1G HA-2 ENSG00000136286 "Myosin IG" B0I1T2 7 44962662-44979088 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.6;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in many" "dendritic cells: 81.3;Langerhans cells: 65.1;Macrophages: 74.2;monocytes: 392.2;NK-cells: 252.4;T-cells: 87.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 52.6;HEL: 64.1;HL-60: 39.9;JURKAT: 85.9;MOLT-4: 97.3;NB-4: 52.1;THP-1: 68.6;U-937: 57.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA021252 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" Nucleoplasm "HPA021252: AB_1854254" "unprognostic (2.74e-2)" "prognostic favorable (8.26e-4)" "unprognostic (5.20e-3)" "unprognostic (9.91e-3)" "unprognostic (1.27e-2)" "unprognostic (1.27e-3)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (4.54e-3)" "unprognostic (6.47e-2)" "unprognostic (6.40e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (8.71e-8)" "unprognostic (3.20e-1)" "unprognostic (2.04e-1)" "unprognostic (1.85e-1)" "unprognostic (7.92e-2)" 2.2 0.8 0.4 16.6 0.3 43.6 1.0 0.3 0.6 0.8 0.3 2.0 3.3 0.7 0.3 1.5 1.2 3.5 0.9 0.3 1.0 0.9 1.3 12.0 25.1 1.4 0.7 0.3 0.7 0.1 0.5 1.2 0.6 1.1 1.8 0.0 2.3 0.7 0.3 0.9 7.8 2.8 0.6 19.0 3.3 0.4 1.6 27.2 1.6 0.4 14.8 6.1 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 52.6 0.0 64.1 2.7 0.0 0.0 39.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 85.9 0.0 0.0 0.0 0.0 97.3 52.1 0.0 0.0 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 68.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 57.3 0.0 41.5 58.3 18.5 61.5 95.5 38.4 27.7 40.5 55.6 42.7 18.9 14.1 29.6 6.0 23.9 129.8 4.5 79.9 79.9 0.4 0.3 0.3 0.6 0.3 1.0 1.4 0.7 0.6 0.6 1.6 0.8 0.9 3.2 7.7 0.0 55.7 2.8 0.4 0.0 0.0 0.2 1.2 1.3 1.1 1.5 1.3 0.0 0.0 0.2 81.3 0.2 0.0 0.3 0.6 0.3 0.5 1.0 0.0 6.3 0.1 1.1 0.3 2.3 2.0 0.6 30.4 0.4 2.2 1.4 10.5 3.3 0.0 0.2 0.0 58.7 65.1 1.6 0.0 74.2 3.6 0.0 392.2 0.3 252.4 0.5 0.0 0.2 0.1 0.4 33.4 0.4 0.0 0.6 0.7 0.2 6.6 2.0 1.4 3.8 1.2 0.2 1.7 0.1 87.1 1.2 0.1 0.2 MYOF "FER1L3, KIAA1207" ENSG00000138119 Myoferlin Q9NZM1 10 93306429-93482334 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 123.4;Pancreatic endocrine cells: 153.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 20.4;non-classical monocyte: 26.6" "Group enriched" "Detected in many" 57 "dendritic cells: 8.1;monocytes: 26.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 452.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014245 Enhanced Supported "Vesicles,Plasma membrane" NA NA 190000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "Plasma membrane" "HPA014245: AB_1848495" "unprognostic (3.41e-2)" "unprognostic (3.85e-1)" "unprognostic (2.88e-2)" "unprognostic (7.44e-2)" "unprognostic (3.50e-2)" "unprognostic (8.57e-3)" "unprognostic (3.48e-2)" "unprognostic (7.75e-2)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.55e-1)" "unprognostic (5.74e-3)" "unprognostic (1.87e-1)" "unprognostic (1.94e-2)" "unprognostic (9.17e-2)" "unprognostic (9.18e-2)" 31.7 8.1 2.9 20.6 4.1 1.5 43.3 5.0 2.5 56.4 37.4 22.4 5.3 27.5 7.1 36.4 36.9 26.6 13.8 3.4 4.1 10.9 2.9 32.2 4.4 8.9 6.8 9.8 5.9 23.8 3.8 55.2 8.1 27.5 29.3 0.9 19.7 31.4 3.6 56.1 9.0 44.3 6.2 6.5 13.4 2.2 5.4 5.1 35.7 6.2 9.1 62.0 29.4 6.2 228.9 206.3 21.4 14.6 159.4 318.4 62.0 190.3 452.7 110.1 109.2 51.1 177.1 0.0 76.9 353.7 116.2 350.0 1.8 204.7 82.6 1.4 0.9 0.0 80.8 2.1 55.2 0.0 0.2 183.0 71.6 77.7 323.8 289.4 299.7 0.0 0.0 0.5 275.6 39.4 0.1 0.9 1.6 72.0 171.6 0.0 15.8 0.1 314.3 281.5 0.1 0.0 130.4 29.7 46.1 83.1 141.5 4.7 378.5 167.3 11.8 111.3 113.9 0.2 0.3 0.3 128.2 2.6 201.0 0.0 5.4 0.0 0.0 20.4 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.3 0.0 26.6 2.8 0.2 1.6 2.9 4.1 5.0 2.5 3.4 4.1 8.9 6.8 8.1 6.2 5.4 6.2 42.5 60.9 52.5 1.6 1.2 23.7 63.0 101.4 39.3 0.1 48.4 34.3 9.2 14.3 91.5 22.0 0.0 56.6 3.8 74.1 1.9 54.8 0.6 50.9 45.9 28.8 1.8 0.0 2.7 33.7 23.7 38.1 23.0 123.4 1.3 1.7 35.7 0.4 22.9 0.0 0.8 29.6 42.7 29.2 20.2 0.6 5.9 28.5 8.8 60.0 12.8 0.1 0.0 2.0 0.7 153.7 22.2 9.1 0.8 86.7 0.6 1.5 60.7 0.8 6.6 15.9 39.6 0.1 0.3 53.4 30.7 51.2 1.9 8.3 18.7 100.7 NCAM2 "MGC51008, NCAM21" ENSG00000154654 "Neural cell adhesion molecule 2" O15394 21 20998409-21543329 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 12.0;brain: 26.0" "Group enriched" "Detected in some" 19 "Astrocytes: 713.0;Excitatory neurons: 866.5;Inhibitory neurons: 909.2;Oligodendrocyte precursor cells: 1729.1;Oligodendrocytes: 1526.6" "Group enriched" "Detected in some" 4 "breast cancer: 2.6;glioma: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "T-47d: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030900, HPA030901" Enhanced Supported Supported "Nuclear bodies,Plasma membrane" No No 120000000 "Cluster 65: Brain - Ion transport" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies, Plasma membrane" "HPA030900: AB_10602037, HPA030901: AB_2673650" "unprognostic (9.70e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (2.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.81e-1)" "unprognostic (1.37e-2)" "unprognostic (3.01e-2)" "unprognostic (5.90e-2)" "unprognostic (1.62e-1)" "unprognostic (1.31e-1)" "unprognostic (5.61e-1)" "unprognostic (3.07e-4)" "unprognostic (2.47e-4)" "unprognostic (1.62e-1)" "unprognostic (8.05e-2)" "unprognostic (1.35e-3)" 0.7 12.0 14.1 0.9 19.0 0.0 1.6 8.4 17.5 1.6 0.0 2.0 0.2 1.0 0.5 0.5 0.6 1.2 2.0 21.3 22.7 0.2 6.7 2.8 0.1 8.6 14.4 0.3 0.2 0.6 0.8 0.5 8.8 0.9 1.0 1.2 0.7 1.0 0.4 0.8 0.7 1.4 8.8 0.8 0.6 6.3 26.0 0.1 0.3 0.8 0.2 0.6 1.2 21.6 0.0 0.0 0.5 0.0 4.6 4.7 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.5 1.3 0.0 0.5 1.3 0.0 2.2 0.0 0.1 11.3 0.0 3.5 0.0 0.4 0.0 0.0 11.4 2.4 0.2 15.4 0.2 0.0 0.4 0.0 0.0 1.0 0.0 4.7 0.0 0.0 0.0 5.3 0.0 0.8 0.6 0.1 92.1 7.2 0.0 1.3 0.9 0.1 0.0 0.6 0.0 0.0 2.5 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 19.0 8.4 17.5 21.3 22.7 8.6 14.4 8.8 8.8 26.0 21.6 0.4 3.2 1.3 713.0 0.1 0.5 0.3 0.0 0.0 1.0 2.0 1.4 1.8 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.0 57.6 0.3 6.1 0.4 0.0 0.0 866.5 0.0 0.4 4.8 0.0 0.2 0.0 0.2 2.2 0.0 0.3 0.0 909.2 0.0 0.0 0.0 0.3 24.7 0.9 0.1 1.8 30.9 0.0 1.0 0.0 1729.1 1526.6 0.0 0.0 0.4 0.0 0.7 0.0 0.1 0.0 0.1 0.0 2.4 1.6 3.7 9.6 0.1 0.1 0.3 0.2 1.9 0.0 0.2 NECTIN4 "LNIR, nectin-4, PRR4, PVRL4" ENSG00000143217 "Nectin cell adhesion molecule 4" Q96NY8 1 161070998-161089558 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 98.9;skin 1: 113.6;vagina: 57.3" "Cell type enriched" "Detected in some" 5 "Syncytiotrophoblasts: 384.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 56.5;HaCaT: 37.0;MCF7: 24.0;OE19: 24.6;SK-BR-3: 47.8;T-47d: 31.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA010775 Enhanced Supported "Plasma membrane" "Secreted in other tissues" No No 170000 "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA010775: AB_1079720" "unprognostic (1.09e-3)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.11e-2)" "unprognostic (5.69e-3)" "unprognostic (2.09e-2)" "unprognostic (6.69e-3)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-3)" "unprognostic (1.13e-1)" "unprognostic (2.24e-8)" "unprognostic (2.98e-2)" "unprognostic (2.43e-1)" "unprognostic (3.68e-2)" "unprognostic (4.97e-2)" 0.4 0.1 0.1 0.5 0.1 0.7 13.7 0.3 0.2 26.5 0.0 1.5 0.7 1.2 6.9 98.9 2.9 3.8 0.1 0.1 0.0 3.1 0.1 3.5 0.1 0.1 0.1 0.0 4.5 0.4 0.6 12.2 0.1 9.4 1.7 0.1 33.6 4.3 0.6 113.6 0.6 0.1 0.0 0.0 8.8 0.6 0.3 0.8 0.2 0.0 14.5 16.8 57.3 0.4 10.9 0.4 0.0 0.1 0.0 0.1 56.5 0.1 0.1 0.1 0.2 0.0 14.6 0.0 0.2 0.0 0.1 37.0 0.0 1.2 0.2 0.0 0.5 0.0 0.8 11.1 0.0 0.1 0.7 0.0 14.6 3.0 3.6 0.1 0.0 0.0 0.0 0.1 0.1 24.0 0.1 0.1 0.1 24.6 0.0 0.0 0.0 0.1 0.0 17.5 0.0 0.2 0.2 47.8 0.0 6.4 31.1 0.0 0.0 0.1 2.4 0.5 0.2 0.2 0.1 0.1 0.1 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.4 0.2 6.4 9.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 41.6 17.8 0.0 0.0 8.1 16.5 0.0 39.4 0.4 0.0 0.0 41.7 0.0 28.1 2.9 0.6 0.0 0.0 0.0 30.0 67.1 1.2 0.0 43.1 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 67.1 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 384.2 0.4 0.1 0.0 0.0 NEO1 "HsT17534, IGDCC2, NGN, NTN1R2" ENSG00000067141 "Neogenin 1" Q92859 15 73051710-73305205 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 231.8;Excitatory neurons: 124.5;Oligodendrocyte precursor cells: 120.1;Oligodendrocytes: 439.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009320, HPA027804, HPA027805, HPA027806" Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 390000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB009320: AB_2150998, HPA027804: AB_10600771, HPA027805: AB_10601755, HPA027806: AB_10601006" "unprognostic (1.90e-1)" "unprognostic (2.38e-2)" "unprognostic (7.60e-3)" "unprognostic (3.76e-2)" "unprognostic (5.44e-1)" "unprognostic (3.83e-2)" "unprognostic (8.30e-2)" "unprognostic (2.31e-1)" "unprognostic (3.22e-1)" "unprognostic (3.30e-2)" "unprognostic (5.51e-2)" "unprognostic (8.05e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.51e-1)" "unprognostic (1.41e-1)" "unprognostic (1.33e-2)" "unprognostic (3.75e-1)" 9.6 7.4 28.9 8.9 43.8 1.5 16.7 38.1 31.4 18.2 10.7 46.0 27.3 19.6 9.9 11.5 21.9 19.6 7.8 29.4 29.2 23.4 8.7 15.9 3.9 34.6 38.0 24.8 17.2 41.8 6.7 1.7 35.6 33.0 55.1 19.5 18.3 36.0 30.9 37.5 26.5 23.3 28.7 5.3 22.9 13.5 36.6 7.2 18.2 24.8 6.2 10.5 9.6 60.0 8.9 42.9 50.1 33.2 29.6 8.6 12.5 3.3 4.1 8.2 1.7 6.4 42.8 2.5 4.9 9.4 30.8 1.9 35.3 19.5 3.5 15.8 26.0 29.0 0.5 6.0 8.6 0.8 0.9 21.3 35.4 1.6 16.2 9.5 0.0 22.3 0.2 53.9 2.0 26.8 10.5 0.7 47.9 6.7 3.6 23.9 26.8 5.8 15.8 23.7 22.7 32.1 40.2 17.6 20.7 39.9 18.6 5.3 0.1 38.0 19.9 12.5 9.3 22.8 45.2 6.2 8.2 8.3 10.9 0.0 0.0 0.1 0.4 0.0 0.7 0.0 0.2 0.3 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.1 28.9 43.8 38.1 31.4 29.4 29.2 34.6 38.0 35.6 28.7 36.6 60.0 3.1 9.6 10.4 231.8 2.3 14.1 8.2 20.7 13.6 15.7 14.2 18.2 6.9 21.5 11.4 22.0 14.6 0.5 4.8 55.6 1.9 11.6 3.3 14.4 13.4 3.4 60.1 3.0 124.5 6.4 0.8 14.6 20.9 24.6 0.0 11.8 5.7 8.9 0.9 10.1 72.8 51.2 10.2 1.2 2.7 7.1 31.7 1.2 10.6 62.8 0.1 12.5 2.1 120.1 439.4 9.9 40.0 62.8 2.6 11.5 39.6 15.5 12.7 21.9 6.6 22.2 10.2 11.8 20.3 14.7 25.4 0.3 6.0 3.1 60.5 7.2 NGFR "CD271, p75NTR, TNFRSF16" ENSG00000064300 "Nerve growth factor receptor" P08138 17 49495293-49515008 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Apoptosis, Biological rhythms, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 52.4;Basal squamous epithelial cells: 36.5;Ionocytes: 89.5;Leydig cells: 96.0;Muller glia cells: 151.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.2" "Group enriched" "Detected in some" 7 "RH-30: 200.1;WM-115: 225.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 10.1" "CAB000143, CAB001995, HPA004765" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 490000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Plasma membrane" "CAB000143: , CAB001995: , HPA004765: AB_1079233" "unprognostic (6.25e-3)" "unprognostic (1.06e-3)" "unprognostic (3.39e-3)" "unprognostic (6.67e-2)" "unprognostic (1.46e-2)" "unprognostic (2.26e-1)" "unprognostic (8.22e-2)" "unprognostic (4.94e-2)" "unprognostic (1.08e-2)" "unprognostic (4.10e-3)" "unprognostic (1.85e-2)" "unprognostic (1.25e-1)" "unprognostic (3.37e-2)" "unprognostic (4.01e-2)" "unprognostic (3.06e-2)" "unprognostic (2.77e-3)" "prognostic unfavorable (3.40e-4)" 36.8 20.7 4.1 8.2 12.1 0.4 20.3 17.3 63.6 13.1 1.4 16.8 2.4 12.0 4.0 6.5 20.2 9.4 40.9 3.2 25.1 8.0 22.8 2.9 5.0 16.9 15.2 4.1 10.9 1.3 10.5 14.7 15.1 19.1 2.4 45.1 21.2 7.6 4.8 15.9 8.0 8.2 10.9 23.0 7.9 7.7 17.2 2.0 28.9 1.3 3.9 15.3 13.2 27.8 0.0 0.1 6.3 10.2 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.1 0.0 2.1 0.1 3.4 4.8 1.5 4.6 0.0 0.4 0.7 0.4 0.0 3.8 0.4 0.3 0.3 20.9 0.3 0.6 1.5 0.1 0.0 0.0 0.0 0.1 29.5 0.6 0.0 0.1 3.8 0.0 0.2 3.9 200.1 0.2 0.0 0.0 1.9 1.3 0.1 0.0 14.0 7.4 0.4 0.2 0.0 0.1 3.4 0.6 10.2 0.2 0.3 0.1 0.2 1.9 225.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 4.1 12.1 17.3 63.6 3.2 25.1 16.9 15.2 15.1 10.9 17.2 27.8 1.2 0.0 0.0 0.0 1.1 3.6 33.1 52.4 36.5 4.8 2.4 10.9 0.7 0.0 3.8 0.0 4.2 0.5 4.0 0.0 0.0 0.1 0.7 0.2 0.6 1.3 0.0 0.0 0.1 0.0 0.5 7.3 0.5 0.2 0.0 0.0 1.8 0.2 0.1 0.0 0.0 0.0 89.5 0.0 3.1 2.9 96.0 0.7 16.0 0.0 0.0 151.7 0.0 0.0 6.5 0.0 0.0 27.8 1.0 3.7 0.0 0.1 1.7 7.0 32.9 1.7 12.9 0.4 0.9 1.8 1.7 0.1 2.3 0.4 0.0 2.9 NINJ2 ENSG00000171840 "Ninjurin 2" Q9NZG7 12 564296-663779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.1" "Cell type enhanced" "Detected in many" "Adipocytes: 29.8;Alveolar cells type 2: 39.9;Erythroid cells: 35.4;Hofbauer cells: 30.7;Kupffer cells: 38.3;Oligodendrocytes: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 153.5;MOLT-4: 263.8;THP-1: 54.4;U-698: 49.3" "Low region specificity" "Detected in all" "HPA058980, HPA067226" Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Centriolar satellite, Cytosol" "HPA058980: AB_2683869, HPA067226: " "unprognostic (1.16e-1)" "unprognostic (2.19e-1)" "unprognostic (9.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.37e-1)" "prognostic favorable (5.31e-4)" "unprognostic (5.72e-3)" "unprognostic (1.90e-3)" "unprognostic (4.60e-2)" "unprognostic (4.98e-3)" "unprognostic (5.88e-2)" "unprognostic (5.12e-2)" "unprognostic (2.68e-2)" "unprognostic (9.05e-2)" "unprognostic (1.03e-2)" "unprognostic (3.51e-3)" "unprognostic (1.23e-1)" 20.6 1.8 21.0 11.3 30.8 38.3 16.5 25.9 29.6 7.8 14.5 5.7 5.2 4.3 2.5 9.6 4.1 5.3 12.2 21.8 23.7 2.1 18.7 36.8 14.8 30.5 26.7 1.0 1.9 0.8 1.5 4.4 28.5 4.3 4.9 0.5 7.4 2.9 38.2 11.3 6.4 5.5 23.9 13.3 4.2 5.5 26.0 8.8 4.0 12.8 11.2 8.5 6.5 45.1 1.7 0.4 0.1 1.8 0.3 0.6 2.9 0.2 0.0 0.0 0.1 3.1 11.8 0.0 0.6 6.1 1.7 0.2 0.2 0.0 0.0 8.6 0.1 153.5 34.2 1.9 0.0 4.3 6.1 2.2 0.2 0.0 0.0 0.0 3.1 3.2 9.0 25.5 0.1 0.1 263.8 8.5 2.6 0.1 0.0 6.8 0.2 0.8 2.7 0.0 0.1 0.0 28.3 0.2 0.0 0.3 0.3 54.4 0.7 0.0 1.5 9.8 0.2 0.1 4.2 49.3 0.4 28.5 0.1 6.7 58.1 48.3 32.8 47.2 9.8 18.8 36.2 34.9 49.9 17.7 7.7 16.7 112.9 21.4 39.4 26.2 157.3 33.4 21.0 30.8 25.9 29.6 21.8 23.7 30.5 26.7 28.5 23.9 26.0 45.1 29.8 22.4 39.9 0.3 5.3 5.7 0.3 2.5 6.2 0.0 1.3 1.3 1.5 1.5 8.7 0.0 0.0 2.6 8.9 2.1 1.9 0.2 3.1 5.5 1.6 9.4 4.2 35.4 1.7 0.0 3.9 13.5 1.1 1.2 2.5 0.4 4.2 11.2 30.7 0.0 1.0 3.5 0.0 38.3 7.8 3.1 8.1 18.0 7.2 11.2 12.4 0.2 7.2 3.5 109.7 0.8 2.6 4.1 8.1 0.1 2.1 0.2 5.0 0.1 0.0 1.3 1.6 3.3 3.1 7.6 5.5 0.8 12.5 0.1 3.1 0.2 NMBR "BB1, BB1R" ENSG00000135577 "Neuromedin B receptor" P28336 6 142058330-142088799 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.5;testis: 1.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3.3;Early spermatids: 7.0;Excitatory neurons: 2.3;Inhibitory neurons: 4.5;Late spermatids: 2.1;Oligodendrocyte precursor cells: 2.0;Oligodendrocytes: 2.5;Spermatocytes: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026665 Supported "Plasma membrane,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA026665: AB_1854527" "unprognostic (6.24e-2)" "unprognostic (3.05e-1)" "unprognostic (2.77e-2)" "unprognostic (7.88e-2)" "unprognostic (3.54e-2)" "unprognostic (8.21e-2)" "unprognostic (3.63e-2)" "unprognostic (1.54e-1)" "unprognostic (3.95e-1)" "unprognostic (7.94e-3)" "unprognostic (3.44e-1)" "unprognostic (2.11e-1)" "unprognostic (8.45e-2)" 0.0 0.0 0.7 0.0 1.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.2 1.3 0.0 0.0 0.1 0.0 1.0 1.1 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.4 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.6 0.2 1.3 1.0 1.1 1.5 1.1 0.5 0.2 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.3 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NME2 "NDPKB, NM23-H2" ENSG00000243678 "NME/NM23 nucleoside diphosphate kinase 2" P22392 17 51165435-51171744 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism, Transcription, Transcription regulation" "Activator, DNA-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 918.0;Gastric mucus-secreting cells: 438.3;Plasma cells: 778.5;Squamous epithelial cells: 1490.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB036213, CAB036214, CAB036215, HPA041113" Approved Supported "Plasma membrane,Midbody ring,Cytosol" Yes NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane, Midbody ring" "CAB036213: , CAB036214: , CAB036215: , HPA041113: AB_2677305" "unprognostic (7.21e-3)" "prognostic unfavorable (4.74e-4)" "unprognostic (4.85e-2)" "unprognostic (1.15e-2)" "unprognostic (8.86e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (6.62e-3)" "unprognostic (5.68e-2)" "unprognostic (2.31e-1)" "unprognostic (1.38e-1)" "unprognostic (6.41e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (2.82e-1)" "unprognostic (9.09e-2)" "unprognostic (8.87e-2)" "unprognostic (3.19e-2)" 503.5 428.3 308.0 259.5 319.0 329.4 489.1 328.0 379.9 439.2 431.1 409.2 335.1 383.4 236.1 610.6 350.6 187.0 403.9 313.7 338.6 478.1 428.4 339.6 288.9 326.6 320.7 500.1 632.0 201.8 234.9 204.8 321.3 367.7 330.4 63.3 432.4 247.5 545.7 540.3 307.6 286.2 326.8 336.0 403.5 77.8 333.3 190.0 305.3 353.7 289.1 463.5 464.2 333.4 1638.6 2233.9 466.1 913.7 969.3 1399.2 1449.2 1091.7 954.0 1404.8 1053.5 1789.7 792.3 1314.3 1662.9 913.0 706.6 956.2 947.3 1273.3 1035.7 1604.8 3283.2 1120.3 1345.8 2513.4 1116.1 1736.0 760.5 1324.1 1420.0 901.9 1466.4 914.6 860.9 856.5 1541.7 773.7 956.1 2741.9 931.3 2144.8 831.4 2974.6 3364.2 875.9 1731.8 2157.2 1417.9 1800.2 1160.6 641.9 674.1 1472.7 1583.0 806.1 1201.7 1268.5 1013.5 1462.8 1158.2 1135.2 1774.8 1520.9 2176.6 1558.1 815.1 919.1 819.2 66.8 243.4 14.0 166.7 325.5 235.6 338.9 211.9 183.3 439.5 259.2 153.5 170.0 13.8 251.6 282.5 478.1 211.2 298.2 308.0 319.0 328.0 379.9 313.7 338.6 326.6 320.7 321.3 326.8 333.3 333.4 9.7 28.9 67.2 0.0 146.8 14.5 8.3 10.8 918.0 0.9 41.6 35.9 0.0 22.8 85.7 5.5 0.0 10.0 10.1 7.1 37.2 47.4 0.6 16.4 34.3 60.9 14.6 298.2 0.0 34.5 27.8 99.0 438.3 21.3 42.9 6.8 22.9 37.6 16.4 0.0 0.0 19.3 8.2 34.8 17.4 2.1 25.7 136.7 10.6 0.0 55.5 0.4 2.1 0.0 0.0 40.7 15.6 12.8 778.5 7.6 11.7 33.8 63.6 0.8 6.6 10.2 43.3 0.6 5.6 1490.1 14.9 8.8 87.0 6.8 25.0 11.0 NMT2 ENSG00000152465 "N-myristoyltransferase 2" O60551 10 15102584-15168693 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 93.6;Hepatocytes: 141.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 14.5;eosinophil: 13.6;gdT-cell: 11.0;MAIT T-cell: 19.8;memory CD4 T-cell: 17.5;memory CD8 T-cell: 12.9;naive CD4 T-cell: 21.8;naive CD8 T-cell: 14.5;NK-cell: 20.8;T-reg: 29.5" "Group enriched" "Detected in many" 8 "granulocytes: 14.5;NK-cells: 20.8;T-cells: 29.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 102.6;TIME: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001303 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus, Plasma membrane, Cytosol" "HPA001303: AB_1079494" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (8.78e-2)" "unprognostic (1.15e-3)" "unprognostic (6.97e-2)" "unprognostic (2.24e-1)" "unprognostic (7.11e-2)" "unprognostic (5.13e-2)" "unprognostic (3.20e-1)" "unprognostic (4.01e-3)" "unprognostic (3.31e-1)" "unprognostic (2.00e-1)" "unprognostic (7.06e-2)" "unprognostic (3.79e-3)" "unprognostic (2.00e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" 25.9 4.4 7.3 6.1 8.7 3.7 17.5 12.2 10.0 9.8 4.0 8.8 6.6 12.7 3.5 7.0 8.3 7.0 8.7 7.0 4.9 9.4 16.8 6.3 8.9 5.0 7.6 15.4 5.6 16.5 5.5 4.4 5.1 9.0 9.2 7.0 5.2 7.7 8.3 10.1 10.9 10.5 4.3 9.4 7.9 13.4 9.1 27.0 5.9 8.5 8.0 8.6 7.9 7.3 8.8 11.3 12.7 9.3 33.7 35.9 2.3 18.8 15.3 17.0 23.0 10.9 38.7 0.4 12.7 102.6 46.6 10.6 11.4 10.7 28.3 11.7 13.9 23.4 5.4 15.2 22.4 1.7 84.0 31.9 10.8 23.8 7.2 62.2 65.8 16.3 11.2 1.5 63.7 10.9 18.3 4.4 9.3 10.0 10.5 13.6 18.5 1.8 12.6 1.8 3.9 14.4 22.8 3.7 6.3 10.5 11.7 7.3 147.1 16.7 24.4 75.0 13.7 13.0 14.3 1.0 20.7 6.3 12.4 14.5 0.5 13.6 11.0 0.7 19.8 2.2 17.5 12.9 0.5 2.5 21.8 14.5 1.9 20.8 0.8 0.5 29.5 6.5 7.3 8.7 12.2 10.0 7.0 4.9 5.0 7.6 5.1 4.3 9.1 7.3 52.5 9.6 8.8 25.1 16.0 16.6 23.4 8.3 7.4 20.6 14.7 13.1 13.5 57.2 10.9 27.6 4.2 1.3 16.9 32.8 9.8 33.9 6.6 4.7 20.5 21.7 18.0 15.1 39.6 19.5 3.0 16.3 9.2 10.3 93.6 13.2 25.4 141.9 2.8 20.2 30.1 11.4 4.1 7.9 7.1 14.5 21.8 5.8 12.4 17.8 10.1 12.9 40.2 12.5 15.3 27.1 15.9 20.7 10.0 17.9 38.4 63.2 5.3 17.2 0.0 13.4 21.0 8.1 46.8 6.8 14.8 2.6 33.9 11.0 18.1 16.7 NMUR2 NMU2R ENSG00000132911 "Neuromedin U receptor 2" Q9GZQ4 5 152391546-152433368 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 6.2" "Group enriched" "Detected in some" 13 "Gastric mucus-secreting cells: 5.1;Oligodendrocytes: 8.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.8;stomach cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "EFO-21: 9.6" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Low region specificity" "Detected in all" "HPA027800, HPA045836" Enhanced Supported "Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA027800: , HPA045836: AB_10968856" "unprognostic (1.82e-1)" "unprognostic (3.83e-1)" "unprognostic (2.66e-1)" "unprognostic (9.29e-2)" "unprognostic (5.87e-2)" "unprognostic (6.44e-3)" "unprognostic (3.13e-1)" "unprognostic (6.47e-2)" "unprognostic (5.63e-2)" "unprognostic (8.20e-3)" "unprognostic (8.90e-5)" "unprognostic (1.48e-2)" "unprognostic (9.24e-2)" "unprognostic (9.56e-2)" "unprognostic (2.29e-1)" 0.0 0.1 1.0 0.0 3.5 0.0 0.0 1.4 1.8 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.7 3.0 0.4 0.0 0.3 0.0 4.5 2.1 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.8 0.0 1.0 1.5 3.0 0.6 0.5 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.4 9.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.5 1.4 1.8 0.7 3.0 4.5 2.1 4.1 3.8 3.0 6.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 NOS1 "nNOS, NOS" ENSG00000089250 "Nitric oxide synthase 1" P29475 12 117208142-117452170 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 23.0;skeletal muscle: 36.9;tongue: 57.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 10.0;Hepatic stellate cells: 18.2;Inhibitory neurons: 32.1;Oligodendrocyte precursor cells: 48.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 4.6;RH-30: 9.4;RPTEC TERT1: 5.8;U-2 OS: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002167, HPA058312, HPA069509" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "CAB002167: AB_564073, HPA058312: AB_2683676, HPA069509: " "unprognostic (1.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.18e-2)" "unprognostic (6.64e-3)" "unprognostic (4.91e-2)" "unprognostic (2.74e-1)" "unprognostic (2.54e-1)" "unprognostic (9.12e-3)" "unprognostic (2.51e-1)" "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" "unprognostic (7.56e-2)" "unprognostic (1.01e-1)" "unprognostic (3.73e-2)" "unprognostic (1.34e-1)" "unprognostic (5.97e-4)" "unprognostic (1.87e-1)" 0.1 0.1 12.7 0.4 12.4 0.2 0.1 5.7 7.0 0.3 0.0 2.2 0.1 0.1 0.2 0.8 0.3 0.0 0.0 4.0 16.2 1.3 0.0 0.8 0.1 12.1 11.0 0.0 1.4 0.0 0.9 0.0 12.2 0.9 0.4 0.3 3.4 0.1 36.9 1.9 0.4 0.3 2.3 0.0 0.2 0.5 23.0 0.0 0.1 57.2 0.1 0.0 0.7 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 4.6 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 9.4 0.0 5.8 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 12.7 12.4 5.7 7.0 4.0 16.2 12.1 11.0 12.2 2.3 23.0 3.3 0.0 0.0 0.0 1.3 0.0 3.8 10.0 2.4 4.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.0 3.0 5.1 0.4 3.0 0.0 0.0 2.0 0.0 0.0 0.7 0.0 8.4 0.0 0.0 18.2 0.0 0.0 0.0 32.1 0.2 0.0 0.3 0.7 0.6 0.3 0.2 1.8 1.9 0.0 0.0 0.0 48.2 5.7 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.1 1.8 0.1 0.6 0.0 0.2 0.0 0.0 1.0 NOTCH2 ENSG00000134250 "Notch receptor 2" Q04721 1 119911553-120100779 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048743 Approved Supported "Nucleoplasm,Plasma membrane" NA NA 160000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane" "HPA048743: AB_2680508" "unprognostic (1.33e-1)" "unprognostic (1.43e-2)" "unprognostic (2.66e-1)" "unprognostic (1.40e-3)" "unprognostic (7.98e-2)" "unprognostic (4.01e-2)" "unprognostic (1.22e-1)" "unprognostic (7.32e-2)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.24e-4)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.86e-2)" "unprognostic (6.12e-3)" "unprognostic (1.55e-2)" "unprognostic (2.65e-2)" "unprognostic (1.12e-2)" "unprognostic (7.35e-3)" 27.1 12.9 16.4 20.4 13.6 13.7 24.8 11.9 16.4 31.0 20.3 16.0 5.4 21.2 20.8 24.9 25.7 18.5 14.2 15.9 13.7 10.9 19.6 20.2 16.7 20.6 18.6 33.9 20.1 12.1 5.5 24.9 13.9 20.4 13.6 19.3 17.1 22.2 6.4 32.3 11.9 26.6 15.7 25.3 10.5 25.4 19.3 15.3 21.2 8.9 17.9 19.0 24.1 14.8 54.2 17.7 27.0 20.7 108.5 92.7 26.6 39.7 54.8 51.8 55.8 16.3 14.2 1.4 32.6 75.3 46.2 20.1 42.8 35.3 82.5 64.0 27.2 32.1 45.7 1.6 40.5 32.7 8.0 75.5 22.5 155.2 103.7 78.4 26.9 14.5 0.8 65.3 63.7 59.2 13.9 9.2 34.6 5.0 19.6 9.1 94.2 36.1 27.3 33.4 1.1 13.4 54.5 50.0 27.9 53.4 28.0 11.7 97.0 67.0 45.8 102.7 63.1 27.9 16.8 16.5 98.7 29.5 65.2 15.0 14.9 22.9 1.4 7.3 1.4 39.0 1.6 0.9 23.7 33.3 3.1 2.0 8.9 2.4 10.5 12.3 3.8 4.4 16.4 13.6 11.9 16.4 15.9 13.7 20.6 18.6 13.9 15.7 19.3 14.8 4.6 35.3 19.5 125.4 36.6 46.3 56.6 14.8 31.3 3.3 38.1 25.3 16.0 24.3 28.5 18.4 6.2 1.6 26.0 6.2 0.0 46.8 17.7 33.8 21.9 5.4 6.1 18.3 4.2 12.9 8.9 67.8 5.1 61.1 15.8 78.3 3.9 41.5 32.7 3.3 22.6 7.9 20.3 74.7 78.2 12.6 55.0 76.6 39.2 43.1 79.3 46.2 15.5 75.4 0.6 26.8 105.5 85.4 14.2 37.2 3.2 4.9 16.4 10.5 19.7 83.6 34.0 10.0 4.3 75.1 88.9 1.6 18.5 22.0 15.8 66.9 NPFFR2 "GPR74, NPFF2, NPGPR" ENSG00000056291 "Neuropeptide FF receptor 2" Q9Y5X5 4 72031804-72148067 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.2;seminal vesicle: 3.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 22.1;Cytotrophoblasts: 6.6;Excitatory neurons: 14.5;Extravillous trophoblasts: 12.3;Muller glia cells: 4.9;Syncytiotrophoblasts: 9.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "GAMG: 28.1;NTERA-2: 9.2;RPTEC TERT1: 11.9;SH-SY5Y: 14.0;U-2 OS: 13.7" "Region enriched" "Detected in some" 4 "olfactory bulb: 4.3" "Low region specificity" "Detected in all" HPA026825 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 63: T-cells - Adaptive immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane" "Actin filaments" "HPA026825: AB_10603123" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (6.07e-2)" "unprognostic (4.68e-2)" "unprognostic (5.77e-2)" "unprognostic (1.43e-2)" "unprognostic (1.34e-1)" "unprognostic (1.51e-1)" "unprognostic (2.40e-5)" "unprognostic (5.75e-2)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (1.48e-1)" 0.1 0.0 1.0 0.2 0.9 0.0 0.2 0.0 0.6 0.1 0.0 0.1 0.1 0.0 0.9 0.0 0.2 0.1 0.0 0.9 1.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 1.6 0.3 0.1 0.2 0.7 0.0 3.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.2 7.2 0.3 0.2 0.1 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 14.0 0.0 0.0 0.0 2.0 0.0 0.0 1.3 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.0 0.6 0.9 1.1 0.5 0.0 0.3 0.0 0.2 0.5 0.1 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 22.1 0.0 0.5 0.0 0.0 0.0 0.0 6.6 0.0 0.1 0.0 0.2 0.8 0.0 0.0 0.3 0.0 0.0 14.5 0.2 12.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.3 3.5 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 1.7 0.0 0.0 9.7 0.0 0.0 0.0 0.1 NRAS N-ras ENSG00000213281 "NRAS proto-oncogene, GTPase" P01111 1 114704469-114716771 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010157, HPA049830, CAB079912" Uncertain Supported "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB010157: AB_632073, CAB079912: AB_2784586, HPA049830: AB_2680903" "unprognostic (4.75e-2)" "unprognostic (2.81e-1)" "unprognostic (1.09e-3)" "unprognostic (2.11e-2)" "unprognostic (8.59e-3)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-7)" "unprognostic (7.76e-3)" "unprognostic (1.57e-2)" "unprognostic (1.01e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (6.60e-3)" "prognostic unfavorable (7.87e-4)" "unprognostic (2.68e-1)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (3.33e-2)" 19.0 9.1 10.3 25.7 11.2 58.5 18.0 11.5 12.3 12.5 8.6 27.8 21.5 12.4 7.8 20.7 10.3 17.2 8.3 10.2 12.2 20.9 24.9 18.5 30.4 12.3 12.1 9.6 11.4 9.0 4.3 28.3 12.3 11.4 26.6 6.6 10.9 7.1 7.7 19.8 22.5 14.1 11.7 18.6 21.8 9.6 11.4 39.0 16.1 7.8 29.7 22.2 8.6 13.4 93.7 24.9 65.2 24.9 26.4 56.3 46.5 43.5 48.4 79.5 89.0 50.4 33.9 70.4 56.3 58.9 55.4 26.0 88.2 70.6 113.4 96.5 34.2 47.8 34.5 60.2 52.3 120.0 71.0 51.1 56.1 91.5 66.2 25.0 102.8 54.6 77.3 78.5 71.0 248.9 83.5 46.4 111.0 30.2 17.9 62.9 116.0 44.1 70.6 49.5 39.4 59.0 44.7 36.4 107.1 75.4 31.9 96.2 79.2 43.3 82.2 81.5 90.3 137.7 101.6 81.6 86.4 64.6 159.0 38.7 12.8 12.6 11.7 19.2 10.5 12.8 9.3 11.6 12.6 10.5 9.9 12.9 3.4 15.5 17.6 9.6 13.4 13.1 10.3 11.2 11.5 12.3 10.2 12.2 12.3 12.1 12.3 11.7 11.4 13.4 22.7 16.0 16.5 8.1 25.9 30.7 31.2 23.1 15.4 5.2 18.5 13.6 5.6 18.6 19.3 22.0 8.4 22.4 27.7 49.2 13.7 34.1 3.9 22.9 24.7 29.2 24.6 31.6 5.8 31.5 50.4 16.1 29.0 38.0 31.1 22.2 33.2 29.7 49.2 5.0 5.2 28.1 30.5 44.9 30.7 5.9 8.1 30.4 23.2 9.4 41.6 7.8 22.6 5.0 8.1 51.4 32.9 6.4 39.6 30.6 28.1 39.4 23.1 3.3 6.6 12.8 15.3 7.3 15.4 24.6 36.2 31.2 21.9 13.8 28.8 40.2 NRXN1 "Hs.22998, KIAA0578" ENSG00000179915 "Neurexin 1" "P58400, Q9ULB1" 2 49918503-51225575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Cell adhesion" "Mental retardation, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 145.0" "Group enriched" "Detected in many" 5 "Astrocytes: 4025.1;Excitatory neurons: 3206.3;Inhibitory neurons: 2116.2;Oligodendrocyte precursor cells: 4897.8" "Cancer enriched" "Detected in single" 8 "glioma: 3.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071400 Supported "Plasma membrane" "Intracellular and membrane" NA NA 1400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA071400: AB_2732180" "unprognostic (7.01e-2)" "unprognostic (9.96e-2)" "unprognostic (7.68e-2)" "unprognostic (1.74e-4)" "unprognostic (2.46e-1)" "unprognostic (8.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.85e-1)" "unprognostic (8.19e-2)" "unprognostic (6.37e-4)" "unprognostic (2.85e-2)" "unprognostic (6.68e-7)" "unprognostic (3.40e-2)" "unprognostic (1.75e-1)" "unprognostic (5.57e-2)" "unprognostic (1.99e-3)" 1.1 2.0 40.9 1.1 60.9 0.3 0.8 145.0 74.4 2.2 0.0 11.3 0.9 1.1 3.0 2.0 0.8 1.2 5.2 62.7 16.8 0.4 0.5 0.4 0.3 0.0 2.2 0.9 1.4 0.0 6.0 0.0 7.2 2.8 2.6 7.2 2.4 8.4 0.2 0.9 2.6 1.0 4.7 0.2 2.3 5.6 15.7 1.2 0.6 0.8 0.2 2.3 3.1 22.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 31.3 1.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 3.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 40.9 60.9 145.0 74.4 62.7 16.8 0.0 2.2 7.2 4.7 15.7 22.0 0.1 0.0 0.0 4025.1 0.0 0.0 0.3 0.0 3.4 116.0 3.1 3.7 19.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.9 0.1 201.6 0.1 2.8 1.0 1.8 0.0 3206.3 0.0 0.0 2.3 0.0 0.1 0.0 0.2 3.3 0.2 0.1 77.4 2116.2 0.0 0.0 0.0 0.6 103.4 2.5 0.6 1.8 174.3 0.0 22.7 0.0 4897.8 678.0 0.2 0.0 0.7 1.4 0.5 0.0 0.2 0.0 9.7 0.0 2.5 1.3 13.3 5.8 0.6 0.1 0.3 0.1 0.1 0.0 0.1 NSD1 "ARA267, FLJ22263, KMT3B, STO" ENSG00000165671 "Nuclear receptor binding SET domain protein 1" Q96L73 5 177133025-177300213 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048431, HPA070333, HPA073705" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "HPA048431: AB_2680388, HPA070333: AB_2686255, HPA073705: AB_2732239" "unprognostic (3.48e-2)" "unprognostic (7.46e-2)" "unprognostic (7.14e-3)" "unprognostic (2.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.67e-2)" "unprognostic (2.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.68e-3)" "unprognostic (8.04e-2)" "unprognostic (1.48e-1)" "unprognostic (2.09e-1)" "unprognostic (7.77e-3)" "unprognostic (3.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.51e-2)" "unprognostic (7.32e-2)" 8.7 7.2 8.9 12.0 13.4 21.2 10.9 26.2 10.4 11.1 9.8 10.1 8.4 11.5 10.3 11.4 10.1 8.0 9.1 7.7 10.0 10.6 6.6 9.2 13.7 9.7 10.8 12.3 11.3 12.8 9.0 10.7 12.2 9.3 10.8 11.9 10.4 9.6 13.6 12.0 9.4 12.0 6.6 11.3 8.9 23.2 12.0 20.2 15.5 11.5 14.7 9.3 7.9 17.5 20.5 25.9 26.0 22.8 12.5 16.1 0.9 18.2 17.9 24.6 22.8 5.7 16.6 41.7 19.9 24.8 22.7 17.0 41.9 40.0 29.7 72.9 25.9 18.6 29.5 0.2 20.7 40.4 21.2 15.2 23.6 29.4 27.3 17.5 36.4 26.0 25.9 14.3 25.2 42.3 28.3 13.1 28.5 13.7 22.5 31.0 3.4 12.9 15.9 24.4 31.6 21.9 46.7 20.1 13.8 24.1 20.2 33.0 27.4 17.1 25.0 11.0 22.6 16.7 15.7 29.5 9.9 19.3 18.7 14.7 9.0 10.5 7.2 6.1 6.0 8.5 6.1 5.0 7.2 10.3 7.5 6.0 18.6 11.3 12.2 9.4 6.4 3.4 8.9 13.4 26.2 10.4 7.7 10.0 9.7 10.8 12.2 6.6 12.0 17.5 37.4 22.4 31.4 84.9 71.7 17.0 32.8 27.2 34.1 94.4 29.8 25.7 44.5 34.3 35.0 55.2 150.1 43.6 66.1 19.7 17.6 27.8 31.9 27.1 65.7 36.4 41.9 48.3 107.0 21.2 23.7 32.7 41.8 41.9 41.7 64.0 33.5 19.9 27.7 89.2 110.3 25.6 12.2 36.8 25.7 50.3 51.0 47.1 16.0 115.2 75.0 29.2 95.8 140.8 157.5 23.7 31.0 33.1 55.8 29.4 33.6 19.2 17.3 112.3 52.6 42.9 36.1 83.7 62.1 41.8 20.6 35.4 62.0 55.9 28.2 30.0 NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 112.6;retina: 94.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 58.0;Oligodendrocyte precursor cells: 61.3;Pancreatic endocrine cells: 124.8;Rod photoreceptor cells: 81.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 33.0;naive CD8 T-cell: 30.7" "Group enriched" "Detected in many" 41 "B-cells: 33.0;T-cells: 30.7" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 807.8;LHCN-M2: 934.3;TIME: 546.2;U-87 MG: 821.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 3000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" 20.7 6.0 9.8 11.9 11.9 0.6 14.1 11.2 10.7 112.6 14.9 29.4 40.1 49.4 6.3 8.6 20.7 17.2 8.7 8.5 11.3 17.2 54.8 6.8 9.6 11.7 14.1 39.3 1.8 1.8 11.8 25.3 13.0 13.3 31.9 94.4 6.6 34.2 2.1 6.4 20.9 73.9 14.7 13.0 8.1 10.4 12.7 5.2 23.7 9.8 11.3 15.8 28.5 12.1 48.9 26.0 42.9 0.8 95.1 302.4 0.4 306.1 332.7 147.5 275.2 0.4 469.6 0.0 107.3 270.2 379.0 24.5 0.1 308.0 348.8 0.8 0.1 0.1 7.3 6.0 47.5 0.2 0.7 77.4 3.7 302.0 191.3 807.8 124.9 0.3 0.3 1.4 934.3 8.3 0.0 0.2 0.8 8.2 34.6 1.5 9.5 1.3 323.1 21.8 0.3 5.5 3.8 18.8 104.9 2.2 0.4 8.3 546.2 120.6 0.9 152.9 506.8 22.7 15.3 0.5 821.7 0.4 385.3 0.0 0.0 0.5 3.7 0.0 6.4 23.7 4.2 11.7 0.0 33.0 4.1 30.7 0.5 0.7 0.0 0.1 1.7 6.4 9.8 11.9 11.2 10.7 8.5 11.3 11.7 14.1 13.0 14.7 12.7 12.1 6.4 0.0 5.8 36.9 21.6 5.2 1.7 6.1 2.8 4.4 1.2 0.3 1.7 27.1 4.8 1.8 10.4 0.6 2.2 49.2 3.9 3.8 0.6 19.3 20.8 20.5 0.0 0.0 1.6 4.1 2.5 39.4 11.2 58.0 0.0 0.1 49.6 33.7 1.3 0.0 2.1 27.7 0.0 3.5 8.2 1.3 13.1 2.1 7.2 11.2 0.5 9.1 0.0 61.3 0.7 124.8 46.0 25.6 3.6 1.5 8.3 27.6 4.8 81.6 0.0 3.3 9.6 0.0 0.3 0.6 4.8 15.2 5.0 0.1 18.0 9.6 NTNG1 "KIAA0976, Lmnt1" ENSG00000162631 "Netrin G1" Q9Y2I2 1 107140007-107484923 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 75.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 59.7;Excitatory neurons: 122.1;Inhibitory neurons: 162.5;Oligodendrocyte precursor cells: 425.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "thalamus: 75.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 48.7;fHDF/TERT166: 25.0;RPTEC TERT1: 27.4;U-138 MG: 21.8;U-251 MG: 16.9;U-87 MG: 24.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "hippocampal formation: 19.7;midbrain: 61.3;pons: 56.0;thalamus: 76.4" HPA065954 Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA065954: AB_2685585" "unprognostic (1.79e-1)" "unprognostic (4.63e-2)" "unprognostic (1.67e-2)" "unprognostic (9.38e-5)" "unprognostic (1.93e-3)" "unprognostic (9.87e-3)" "unprognostic (3.34e-1)" "unprognostic (8.38e-3)" "unprognostic (1.03e-1)" "unprognostic (2.02e-1)" "unprognostic (5.68e-2)" "unprognostic (2.05e-2)" "unprognostic (3.10e-4)" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (1.93e-5)" 3.1 4.4 17.2 0.2 3.8 0.0 0.2 6.3 6.7 3.2 0.0 2.2 0.0 0.6 0.0 0.1 0.4 0.6 0.1 7.8 15.2 8.8 0.0 3.8 0.4 5.8 28.3 0.4 0.1 0.1 2.5 1.1 4.6 3.4 0.4 10.3 0.2 4.7 0.0 1.3 0.4 0.1 3.2 0.3 0.2 0.4 75.1 0.5 0.1 0.2 0.6 4.0 1.8 2.7 0.0 0.0 2.8 0.0 5.0 48.7 0.0 13.9 2.1 1.2 1.1 0.0 0.0 0.0 0.6 25.0 0.0 0.0 0.0 1.5 2.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 13.9 0.3 3.5 1.8 14.7 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 1.0 0.0 6.1 0.0 3.1 0.0 27.4 0.0 0.3 0.4 0.0 0.0 0.0 0.8 0.0 0.1 0.2 21.8 4.3 8.1 16.9 0.1 0.0 0.0 24.8 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.0 17.2 3.8 6.3 6.7 7.8 15.2 5.8 28.3 4.6 3.2 75.1 2.7 0.2 0.0 0.0 46.4 3.1 0.5 6.5 0.4 0.0 59.7 0.1 0.0 0.9 0.0 0.2 7.3 0.0 0.1 0.0 0.0 0.0 0.0 10.5 0.1 0.8 0.9 0.0 0.0 122.1 0.0 0.0 2.8 0.0 0.4 0.0 6.1 0.4 0.0 0.0 0.0 162.5 0.0 6.1 0.0 1.3 1.8 8.1 0.0 1.8 18.7 0.0 1.0 0.0 425.3 2.5 0.3 0.0 0.0 1.0 1.1 0.0 0.0 0.0 2.9 6.6 0.2 2.7 0.2 1.1 0.1 0.6 0.0 0.1 7.2 0.0 4.3 NTRK2 TRKB ENSG00000148053 "Neurotrophic receptor tyrosine kinase 2" Q16620 9 84668551-85027054 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 230.0;thyroid gland: 116.9" "Cell type enhanced" "Detected in many" "Astrocytes: 1144.3;Excitatory neurons: 750.1;Inhibitory neurons: 877.7;Oligodendrocyte precursor cells: 557.9" "Group enriched" "Detected in many" 5 "glioma: 31.6;head and neck cancer: 8.0;lung cancer: 9.8;thyroid cancer: 26.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.7;HaCaT: 3.0;RPTEC TERT1: 9.7;SH-SY5Y: 11.2;SuSa: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007637, CAB010346, HPA074873" Enhanced Supported "Plasma membrane" NA NA 20000000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB010346: AB_2155274, HPA007637: AB_1080385, HPA074873: " "unprognostic (2.75e-3)" "unprognostic (3.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.26e-2)" "unprognostic (2.56e-2)" "unprognostic (1.29e-2)" "unprognostic (9.16e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (4.25e-2)" "unprognostic (2.18e-2)" "unprognostic (2.66e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-3)" 40.5 2.7 201.9 1.7 177.8 0.1 62.2 133.3 190.6 9.8 69.8 5.9 0.4 3.9 3.9 8.2 5.6 33.3 15.2 173.3 230.0 20.4 1.8 10.0 3.1 119.4 218.9 9.7 34.3 2.5 10.1 1.8 151.7 4.7 3.6 41.2 14.4 19.1 2.9 11.6 1.6 3.3 116.6 10.9 1.9 2.4 222.1 4.0 116.9 13.8 4.3 4.9 12.0 117.7 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 9.7 0.7 0.7 11.2 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 201.9 177.8 133.3 190.6 173.3 230.0 119.4 218.9 151.7 116.6 222.1 117.7 17.4 0.0 0.5 1144.3 0.7 56.6 1.0 1.8 93.9 30.3 144.1 116.8 11.4 0.0 0.2 9.2 6.2 0.0 1.0 8.7 27.4 36.1 1.8 1.2 0.4 8.0 0.0 0.0 750.1 0.7 0.1 76.6 0.0 2.3 0.0 0.1 5.0 0.0 0.2 242.3 877.7 0.7 0.0 0.0 14.2 3.6 104.1 1.4 17.8 65.6 0.6 241.0 0.0 557.9 109.5 0.5 7.0 48.2 0.3 0.9 0.0 7.1 1.7 12.2 124.9 9.9 114.4 0.8 2.3 5.2 24.6 0.0 3.3 0.2 7.2 0.9 NTSR1 NTR ENSG00000101188 "Neurotensin receptor 1" P30989 20 62708836-62762771 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "brain: 11.2;intestine: 11.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.4;Cardiomyocytes: 1.1;Excitatory neurons: 1.6;Inhibitory neurons: 1.3;Kupffer cells: 2.9;Microglial cells: 1.0;monocytes: 1.4" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.9" "Region enriched" "Detected in many" 7 "midbrain: 11.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "PC-3: 57.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050299 Supported "Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA050299: " "unprognostic (4.14e-2)" "unprognostic (2.02e-2)" "unprognostic (2.75e-2)" "unprognostic (8.87e-4)" "unprognostic (9.27e-3)" "unprognostic (1.45e-1)" "unprognostic (4.17e-2)" "unprognostic (2.80e-3)" "unprognostic (7.16e-2)" "unprognostic (3.10e-3)" "unprognostic (3.55e-2)" "unprognostic (2.53e-1)" "unprognostic (1.27e-2)" "unprognostic (1.25e-1)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" 0.0 0.0 1.1 0.0 1.5 0.6 0.0 0.0 1.4 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.4 11.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 2.0 10.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 2.8 0.2 2.7 0.3 1.1 57.7 1.8 0.0 9.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 10.8 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.5 0.0 1.4 1.4 0.4 0.4 11.2 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 4.4 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.9 0.3 0.0 0.0 0.5 0.0 1.0 1.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 OCLN PPP1R115 ENSG00000197822 Occludin Q16625 5 69492292-69558104 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 31.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 109.0;Glandular and luminal cells: 119.7;Urothelial cells: 224.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.7" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.7" "Cell line enhanced" "Detected in many" "A-431: 23.3;CAPAN-2: 39.8;HaCaT: 33.4;RPTEC TERT1: 25.7;SK-BR-3: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005933, CAB013075, CAB068212, CAB068213, CAB068214" Enhanced Supported "Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" "CAB013075: AB_2533101, CAB068212: AB_2665711, CAB068213: AB_2665712, CAB068214: AB_2665713, HPA005933: AB_1079520" "unprognostic (2.28e-1)" "unprognostic (1.88e-1)" "unprognostic (2.50e-2)" "unprognostic (9.94e-2)" "unprognostic (3.65e-1)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.08e-2)" "unprognostic (8.25e-2)" "unprognostic (8.20e-2)" "unprognostic (2.58e-2)" "unprognostic (3.48e-1)" "prognostic favorable (6.59e-11)" "unprognostic (2.83e-1)" "unprognostic (4.01e-1)" "unprognostic (1.33e-1)" "unprognostic (3.35e-1)" 1.2 0.7 6.2 1.6 6.5 1.8 7.8 7.2 6.7 6.8 22.2 11.0 10.3 2.1 4.0 11.6 7.5 8.5 1.5 5.9 5.4 11.0 18.8 15.1 0.6 9.3 7.7 2.3 20.2 8.3 3.4 3.9 8.3 3.5 11.2 2.3 6.7 4.6 0.6 11.3 10.0 0.6 5.4 2.1 15.2 2.4 6.5 0.9 31.4 0.6 2.8 5.0 7.9 7.4 23.3 4.5 0.6 0.9 0.6 0.9 15.1 0.3 1.6 2.5 3.3 20.7 39.8 0.5 5.9 1.1 8.3 33.4 7.2 4.3 7.8 0.3 12.2 2.4 1.1 9.8 0.3 1.2 2.5 0.1 6.4 4.1 1.0 1.6 1.4 3.1 0.1 0.4 0.1 22.4 1.5 1.2 3.1 8.0 2.1 0.2 6.0 1.1 25.7 22.2 2.7 2.8 0.3 27.2 0.9 5.0 14.7 4.0 1.2 0.4 7.7 1.8 2.7 0.5 0.4 0.3 0.3 0.3 0.6 1.0 0.2 0.5 0.2 0.1 0.2 0.3 0.2 0.1 0.1 0.4 0.2 0.2 2.7 0.5 0.1 0.4 0.1 0.1 6.2 6.5 7.2 6.7 5.9 5.4 9.3 7.7 8.3 5.4 6.5 7.4 4.8 109.0 67.3 1.6 3.2 3.7 60.8 7.6 1.8 5.7 49.7 16.9 1.4 64.3 51.0 25.8 14.6 30.3 3.6 94.1 9.8 65.6 1.9 78.5 12.1 10.7 26.3 2.5 1.3 61.6 2.5 5.8 46.4 119.7 2.5 6.5 18.2 48.3 3.0 6.7 1.1 45.1 16.2 12.9 1.2 1.6 3.1 2.4 1.8 16.9 3.9 2.8 1.0 0.5 1.5 64.6 61.8 1.5 1.1 101.5 42.3 10.5 63.0 6.3 13.1 3.3 4.4 4.7 8.2 29.5 15.5 16.4 4.3 0.7 47.9 224.0 OGT "FLJ23071, HRNT1, MGC22921, O-GLCNAC, OGT1" ENSG00000147162 "O-linked N-acetylglucosamine (GlcNAc) transferase" O15294 X 71533104-71575892 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Chromatin regulator, Glycosyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030751, HPA030752, HPA030753, HPA030754, CAB034099" Approved Supported "Nucleoplasm,Plasma membrane" Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 50: Non-specific - Ribosome" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Plasma membrane" "CAB034099: AB_2157067, HPA030751: AB_10600217, HPA030752: AB_10601445, HPA030753: AB_2673594, HPA030754: AB_2673595" "unprognostic (1.37e-1)" "unprognostic (2.20e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.33e-4)" "unprognostic (3.40e-2)" "prognostic favorable (1.97e-4)" "unprognostic (9.56e-3)" "unprognostic (1.96e-3)" "unprognostic (5.58e-2)" "unprognostic (2.29e-1)" "unprognostic (1.06e-1)" "unprognostic (9.74e-3)" "prognostic unfavorable (2.36e-6)" "unprognostic (2.99e-3)" "unprognostic (2.28e-1)" "unprognostic (8.03e-3)" "prognostic favorable (6.85e-7)" 59.3 55.9 39.7 38.3 42.4 61.5 62.7 43.3 51.6 72.7 40.1 62.5 30.6 56.0 62.2 52.8 76.4 26.4 55.5 43.9 35.5 61.6 45.8 70.7 71.9 36.1 35.8 85.5 102.4 24.3 46.9 26.4 37.9 75.4 39.6 36.9 64.1 27.1 62.8 68.6 86.4 24.5 36.1 122.8 67.4 19.0 36.2 57.2 70.7 39.2 57.8 55.7 67.4 44.3 40.5 37.0 47.1 41.5 49.6 45.6 31.6 30.3 54.3 32.1 49.1 39.3 45.4 47.9 20.7 37.3 33.3 49.1 52.0 29.5 39.4 41.1 53.4 30.4 98.6 28.5 37.6 62.9 48.1 43.6 59.2 35.1 65.7 55.5 30.5 100.7 31.1 160.4 31.1 34.3 48.9 75.2 31.6 35.5 49.8 47.8 52.7 62.1 50.0 45.9 24.1 21.2 46.9 30.9 30.2 35.5 22.8 42.4 35.5 34.6 27.9 36.6 17.9 43.5 33.5 56.5 24.4 65.0 21.6 2.8 4.6 2.0 7.5 5.7 6.8 7.4 6.3 6.2 6.1 6.2 7.2 7.4 1.9 10.4 5.7 6.2 6.2 5.6 39.7 42.4 43.3 51.6 43.9 35.5 36.1 35.8 37.9 36.1 36.2 44.3 31.1 35.3 85.2 52.9 67.2 88.1 37.9 23.5 58.6 26.5 49.6 34.0 42.8 20.0 31.1 49.7 8.4 15.8 130.7 31.1 9.8 14.4 2.4 32.1 49.8 39.8 34.9 51.3 110.7 14.4 8.5 47.5 54.6 53.3 27.8 26.4 45.7 27.5 16.1 40.4 94.6 37.3 22.4 60.9 69.7 4.8 53.4 45.8 35.6 71.2 51.6 11.3 51.5 92.0 97.9 17.6 34.9 29.7 147.2 53.8 34.8 15.1 28.0 21.8 32.9 44.8 42.2 2.5 6.1 63.3 84.1 10.9 82.1 62.0 34.0 50.8 OLFM4 "GC1, GW112, OlfD" ENSG00000102837 "Olfactomedin 4" Q6UX06 13 53028813-53052057 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1296.1;pancreas: 671.4" "Cell type enhanced" "Detected in many" "Ductal cells: 497.1;Exocrine glandular cells: 900.9;Intestinal goblet cells: 791.9;Pancreatic endocrine cells: 933.7;Paneth cells: 556.9;Undifferentiated cells: 2419.9;Urothelial cells: 1989.0" "Group enriched" "Detected in many" 14 "colorectal cancer: 711.4;pancreatic cancer: 594.7;stomach cancer: 724.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 5.4;BJ hTERT+: 18.8;HaCaT: 26.4;OE19: 10.4;RPMI-8226: 6.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA077718 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" "Secreted to digestive system" Yes NA 9300 "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA077718: AB_2732358" "prognostic favorable (8.77e-4)" "unprognostic (4.84e-2)" "unprognostic (1.65e-3)" "unprognostic (2.33e-1)" "unprognostic (7.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.74e-2)" "unprognostic (5.16e-2)" "unprognostic (1.40e-1)" "unprognostic (1.22e-1)" "unprognostic (4.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.29e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-2)" "unprognostic (4.84e-3)" 1.9 0.1 0.2 195.4 0.5 126.0 6.8 0.1 0.5 7.9 0.2 451.6 1211.9 5.5 3.5 0.8 8.3 10.4 0.8 0.2 0.4 26.9 0.9 3.8 1.4 0.1 0.2 0.2 671.4 0.0 0.5 0.6 0.2 92.4 568.7 0.4 16.2 0.9 0.6 0.4 1296.1 52.6 0.2 18.0 16.1 0.3 0.2 4.2 0.4 2.1 0.2 127.0 285.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 5.4 2.4 18.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 26.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 10.4 0.0 0.0 0.8 6.2 0.2 0.0 1.1 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.6 0.9 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.5 0.2 0.4 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.3 3.8 0.1 168.5 0.3 0.0 0.0 9.8 2.5 0.5 0.0 11.9 139.8 0.0 0.0 0.0 98.7 1.9 497.1 0.2 13.5 0.5 1.4 92.3 0.8 1.0 900.9 0.0 1.5 0.0 17.6 0.0 0.0 0.0 0.0 0.1 0.0 0.3 791.9 2.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 10.3 4.0 0.0 0.0 0.2 933.7 556.9 0.0 0.4 209.4 300.6 0.0 0.5 0.2 0.0 2.1 9.2 0.0 0.1 0.0 0.0 0.0 3.1 0.2 2419.9 1989.0 OLR1 "CLEC8A, LOX-1, SCARE1" ENSG00000173391 "Oxidized low density lipoprotein receptor 1" P78380 12 10158301-10172138 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.6;lung: 100.2;placenta: 114.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 399.0;Hofbauer cells: 202.1;Macrophages: 202.6;Syncytiotrophoblasts: 463.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CACO-2: 125.4;HaCaT: 64.9;HHSteC: 125.1;hTCEpi: 58.4;SiHa: 248.8;SK-BR-3: 96.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050798 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1060000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" Vesicles "HPA050798: AB_2756318" "unprognostic (2.30e-1)" "unprognostic (3.16e-2)" "unprognostic (1.58e-2)" "unprognostic (1.32e-1)" "unprognostic (7.81e-2)" "prognostic unfavorable (8.24e-5)" "unprognostic (6.34e-2)" "unprognostic (6.07e-3)" "unprognostic (5.40e-2)" "unprognostic (2.64e-1)" "unprognostic (1.97e-2)" "unprognostic (3.51e-1)" "unprognostic (1.08e-1)" "unprognostic (4.94e-3)" "unprognostic (3.47e-2)" "unprognostic (1.48e-2)" "unprognostic (1.42e-1)" 3.0 3.3 9.0 29.1 13.1 23.8 3.6 18.9 16.9 3.3 8.8 0.7 1.3 1.6 1.3 0.5 2.1 7.4 1.5 9.4 13.3 8.2 3.1 100.2 0.7 25.5 15.6 0.3 2.2 4.1 2.7 114.5 26.0 2.3 1.0 5.1 3.8 1.0 0.5 0.6 1.2 2.1 27.6 0.8 2.3 4.7 24.0 2.8 2.5 0.0 0.8 6.0 0.3 52.6 7.3 0.5 0.1 0.3 0.3 0.0 16.8 12.1 2.2 7.3 2.6 125.4 0.1 1.6 0.0 15.8 0.5 64.9 0.0 0.7 4.9 0.0 0.0 0.0 6.1 0.0 125.1 0.1 0.3 1.0 58.4 0.3 0.0 0.0 0.3 0.1 0.1 0.7 0.0 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.2 0.3 0.2 13.3 0.4 0.2 248.8 96.9 0.0 17.4 27.1 0.0 0.1 0.2 1.4 0.0 0.0 0.4 0.3 0.4 0.1 0.1 0.1 0.6 0.6 1.3 0.1 0.1 0.1 0.1 0.1 0.0 2.8 0.2 0.1 0.1 1.4 0.1 0.1 0.3 0.1 0.6 9.0 13.1 18.9 16.9 9.4 13.3 25.5 15.6 26.0 27.6 24.0 52.6 1.9 28.9 27.4 0.0 4.0 1.5 0.4 0.5 0.0 0.4 1.1 4.6 0.1 1.5 4.4 0.0 0.0 399.0 0.3 0.0 0.0 0.1 13.4 0.1 0.0 10.8 0.0 0.4 2.3 0.0 14.6 10.9 0.5 0.1 15.2 0.0 0.0 0.5 202.1 0.0 0.2 0.0 0.0 18.9 79.5 11.6 0.3 202.6 0.0 40.3 21.3 0.1 0.0 0.5 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.2 6.6 0.2 0.0 0.2 0.4 0.1 0.2 0.8 0.6 463.1 1.6 0.1 0.0 0.3 OPRK1 "KOR, OPRK" ENSG00000082556 "Opioid receptor kappa 1" P41145 8 53225724-53251637 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 14.5" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 4.5;Excitatory neurons: 6.7;Extravillous trophoblasts: 8.0;Glandular and luminal cells: 9.8;Inhibitory neurons: 10.1;Leydig cells: 4.7" "Cancer enhanced" "Detected in some" "prostate cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-937: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067549 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Ion transport" "Cluster 32: U-937 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA067549: AB_2732770" "unprognostic (1.01e-1)" "unprognostic (1.17e-2)" "unprognostic (8.70e-3)" "unprognostic (3.73e-2)" "unprognostic (6.74e-2)" "unprognostic (2.22e-3)" "unprognostic (8.09e-2)" "unprognostic (9.71e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" "unprognostic (3.35e-2)" "unprognostic (9.54e-4)" "unprognostic (1.61e-1)" 0.1 0.1 7.3 0.0 14.5 0.0 0.0 1.3 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.9 5.4 0.0 0.0 0.1 0.0 5.8 1.7 0.0 0.0 0.0 0.0 0.2 5.1 1.6 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.7 6.9 0.1 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 21.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 14.5 1.3 8.3 3.9 5.4 5.8 1.7 5.1 0.3 6.9 2.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 1.3 0.0 0.0 0.0 0.2 4.5 0.6 0.1 0.0 0.0 6.7 0.0 8.0 0.1 0.0 9.8 0.0 0.0 0.0 0.0 0.2 0.0 10.1 0.0 0.0 0.0 0.0 0.3 4.7 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 OR10P1 "OR10P1P, OR10P2P, OR10P3P, OST701" ENSG00000175398 "Olfactory receptor family 10 subfamily P member 1" Q8NGE3 12 55636860-55637854 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA074114 Supported "Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "HPA074114: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR13C2 ENSG00000276119 "Olfactory receptor family 13 subfamily C member 2" Q8NGS9 9 104604671-104605627 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Supported "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "HPA078297: " 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.2 0.8 0.3 0.9 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR13C5 ENSG00000277556 "Olfactory receptor family 13 subfamily C member 5" Q8NGS8 9 104598457-104599413 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Supported "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "HPA078297: " "unprognostic (4.88e-2)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.1 0.0 0.2 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.3 0.2 0.5 0.5 0.4 0.8 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR6C6 ENSG00000188324 "Olfactory receptor family 6 subfamily C member 6" A6NF89 12 55293988-55296569 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051090 Uncertain Approved "Lipid droplets,Plasma membrane" NA NA "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Lipid droplets, Plasma membrane" "HPA051090: AB_2681341" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR8S1 ENSG00000284723 "Olfactory receptor family 8 subfamily S member 1" Q8NH09 12 48525632-48528103 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Spermatocytes: 4.0;Spermatogonia: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045595 Uncertain Supported "Plasma membrane" NA NA "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Plasma membrane" "HPA045595: AB_10964447" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OSBPL7 "MGC71150, ORP7" ENSG00000006025 "Oxysterol binding protein like 7" Q9BZF2 17 47807372-47821834 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 29.5;Gastric mucus-secreting cells: 118.7;Paneth cells: 29.9;Proximal enterocytes: 34.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 43.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036076, HPA053083, HPA073967" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 14: B-cells - Humoral immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA036076: AB_10601042, HPA053083: AB_2682038, HPA073967: " "unprognostic (3.88e-2)" "unprognostic (2.01e-1)" "unprognostic (2.25e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (6.55e-3)" "unprognostic (2.05e-3)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (3.33e-1)" "unprognostic (1.97e-1)" "unprognostic (6.78e-2)" "prognostic unfavorable (8.30e-4)" "unprognostic (2.17e-1)" "unprognostic (1.36e-1)" "unprognostic (3.08e-1)" "prognostic favorable (1.19e-5)" 5.0 3.7 10.6 4.9 10.4 7.2 5.4 9.5 14.0 11.1 7.3 22.7 22.3 8.6 1.6 3.4 7.6 5.3 6.5 10.3 9.9 9.9 2.2 8.5 7.5 10.6 10.2 9.6 17.3 2.6 10.1 2.3 10.7 14.3 8.7 3.1 9.0 6.1 20.2 1.7 22.7 3.5 9.2 17.2 34.0 1.4 10.5 4.9 11.3 3.5 3.8 9.1 7.0 10.9 6.0 6.9 3.0 3.4 3.3 4.6 2.5 2.2 3.2 3.7 4.2 7.1 17.8 6.0 8.7 3.2 1.3 43.2 1.7 4.8 1.2 20.8 2.4 4.4 15.0 4.8 3.0 9.4 0.1 7.4 0.9 2.4 1.7 11.5 7.7 10.5 4.4 8.1 5.8 7.8 9.5 10.0 1.8 23.8 8.9 8.6 4.7 8.3 5.0 4.5 3.1 7.0 3.7 1.2 3.3 3.7 6.4 5.9 8.9 5.6 4.9 0.0 1.8 14.6 5.8 5.8 6.1 7.9 2.2 0.0 0.6 0.6 1.8 0.4 0.8 1.0 0.7 1.1 0.6 0.4 0.5 0.8 0.3 0.4 0.0 1.0 0.9 0.9 10.6 10.4 9.5 14.0 10.3 9.9 10.6 10.2 10.7 9.2 10.5 10.9 5.5 0.0 3.9 10.4 4.5 0.1 1.1 2.5 1.2 6.1 2.9 2.5 2.7 1.5 7.4 3.7 6.2 0.2 15.4 29.5 0.0 2.7 0.1 2.1 2.7 4.3 6.0 3.2 7.3 14.7 0.1 2.0 118.7 1.7 2.5 7.1 5.3 0.5 2.7 11.8 6.3 25.8 4.1 3.4 0.8 0.3 2.8 2.3 1.8 1.0 2.7 7.1 8.2 3.5 9.3 9.3 29.9 2.6 11.4 1.7 34.5 1.2 3.4 8.2 0.0 2.5 1.9 0.0 0.3 1.3 0.1 0.5 10.0 3.3 17.6 1.3 OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985719-96994730 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 13 "Extravillous trophoblasts: 49.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "myeloid DC: 1.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 7 "dendritic cells: 2.1" "Cell line enhanced" "Detected in some" "RT4: 3.3;SK-BR-3: 1.4;U-2 OS: 1.6" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA067673: AB_2685883" "unprognostic (1.83e-1)" "unprognostic (1.01e-2)" "unprognostic (1.33e-1)" "unprognostic (6.97e-4)" "unprognostic (7.23e-2)" "unprognostic (1.52e-1)" "unprognostic (8.38e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (2.22e-2)" "unprognostic (4.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (9.68e-2)" 1.3 0.0 1.0 1.3 0.8 0.1 4.2 0.5 1.5 1.0 0.5 2.0 0.2 0.5 2.5 2.1 1.6 0.1 0.2 0.8 2.1 4.0 0.0 0.4 0.1 1.2 1.3 0.1 0.5 0.3 0.3 0.9 1.0 0.5 1.6 0.0 3.0 0.4 0.2 2.6 0.4 0.5 0.7 0.4 0.2 0.1 2.6 0.3 0.5 0.3 0.8 1.7 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.1 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 1.0 0.8 0.5 1.5 0.8 2.1 1.2 1.3 1.0 0.7 2.6 1.3 0.8 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.6 0.0 1.7 1.4 0.2 0.0 0.0 0.0 0.0 2.4 0.1 0.2 1.9 0.0 0.2 0.7 0.1 0.8 1.2 0.0 0.6 0.0 49.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.6 0.5 0.0 0.0 0.4 0.1 0.0 0.3 3.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.9 0.0 0.0 2.2 0.0 3.7 0.0 0.0 1.2 0.0 PACSIN2 SDPII ENSG00000100266 "Protein kinase C and casein kinase substrate in neurons 2" Q9UNF0 22 42835412-43015149 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 95.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049854, HPA056520" Enhanced Supported "Nuclear speckles,Vesicles,Plasma membrane,Cytosol" NA NA 2400000 "Cluster 52: Eosinophils - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles, Vesicles, Cytosol" "Plasma membrane" "HPA049854: AB_2680915, HPA056520: AB_2683163" "unprognostic (5.62e-3)" "unprognostic (1.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.64e-3)" "unprognostic (1.63e-2)" "unprognostic (3.96e-1)" "prognostic unfavorable (7.33e-4)" "unprognostic (4.48e-2)" "unprognostic (3.40e-2)" "unprognostic (2.82e-3)" "unprognostic (3.09e-2)" "unprognostic (1.00e-1)" "prognostic favorable (1.09e-13)" "unprognostic (2.87e-1)" "unprognostic (1.11e-1)" "unprognostic (6.20e-2)" "unprognostic (2.95e-1)" 40.8 74.3 25.7 37.1 29.1 29.3 40.7 34.2 27.3 37.5 32.3 61.7 40.8 39.1 21.2 34.1 35.3 45.3 55.7 27.7 39.2 47.1 41.1 50.9 34.2 40.5 36.8 31.4 162.4 29.4 39.9 34.2 40.8 47.0 41.6 28.2 43.5 27.4 49.8 39.5 38.1 30.4 30.7 35.9 51.5 19.5 32.5 28.7 43.9 42.4 26.4 36.5 34.5 31.1 76.3 78.3 64.6 41.5 32.6 34.6 52.9 67.8 40.7 59.9 49.7 82.1 43.8 35.2 56.1 50.6 40.8 52.8 42.5 72.1 39.3 36.1 42.4 56.8 39.4 117.8 46.1 40.5 118.1 33.4 69.8 79.1 34.3 48.7 49.9 32.1 49.9 24.9 52.2 49.7 43.1 63.3 35.6 110.4 32.7 52.3 96.5 23.8 68.9 44.4 41.9 18.7 81.1 55.2 155.8 41.5 40.1 53.1 74.3 44.5 56.4 50.0 40.5 18.4 27.2 38.4 42.7 35.4 99.1 26.1 18.5 47.4 6.8 32.2 7.3 11.3 7.8 5.8 21.5 11.6 7.6 5.8 95.7 16.8 33.9 7.9 12.1 14.1 25.7 29.1 34.2 27.3 27.7 39.2 40.5 36.8 40.8 30.7 32.5 31.1 31.7 70.5 60.6 20.2 20.6 23.2 43.4 23.9 21.1 15.7 37.4 31.1 26.3 24.3 37.2 46.0 39.6 34.4 19.9 142.6 45.0 80.2 3.6 51.6 31.3 28.6 24.7 12.6 22.7 65.4 29.6 20.9 36.7 57.4 71.0 14.7 16.1 22.3 42.7 6.7 41.0 49.5 30.5 38.5 50.0 6.2 21.8 44.9 83.6 54.4 51.3 8.4 7.2 29.1 19.5 70.9 62.3 23.3 13.1 50.6 32.0 55.0 30.7 24.9 92.1 23.5 82.9 22.6 27.6 22.5 16.9 48.2 19.1 13.8 42.2 30.3 PAK1 ENSG00000149269 "P21 (RAC1) activated kinase 1" Q13153 11 77322017-77474635 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Exocytosis" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 219.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 9 "classical monocyte: 182.2;eosinophil: 292.7;intermediate monocyte: 177.7;myeloid DC: 264.3;neutrophil: 431.8;non-classical monocyte: 202.6" "Group enriched" "Detected in all" 11 "dendritic cells: 264.3;granulocytes: 431.8;monocytes: 202.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003565, CAB005312" Enhanced Supported Supported "Plasma membrane,Cytosol" NA NA 560000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "CAB005312: AB_2160720, HPA003565: AB_1854935" "unprognostic (1.15e-2)" "unprognostic (3.23e-2)" "prognostic favorable (5.87e-4)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (6.62e-2)" "unprognostic (8.19e-3)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-3)" "unprognostic (1.86e-2)" "unprognostic (2.76e-1)" "unprognostic (1.02e-1)" "unprognostic (6.91e-2)" "unprognostic (1.57e-1)" "unprognostic (4.00e-3)" "unprognostic (1.52e-2)" 12.7 13.4 32.4 33.9 44.5 59.0 18.2 13.9 57.7 21.1 0.0 43.2 43.1 20.9 29.8 21.4 21.9 30.9 9.4 58.3 8.0 26.1 14.5 16.8 20.4 19.2 12.2 21.1 17.5 20.5 20.7 14.7 19.4 19.1 46.5 25.1 19.9 19.7 87.0 16.2 45.7 27.0 0.9 29.3 41.2 25.7 17.1 29.1 40.6 18.8 23.1 27.7 20.7 30.0 39.9 26.7 56.7 25.5 22.8 37.6 45.9 44.6 32.1 42.0 48.7 38.7 52.8 36.3 16.0 39.4 54.4 20.2 40.2 47.8 65.5 41.4 32.6 38.2 17.6 2.3 15.3 64.3 53.5 28.2 28.8 49.2 73.1 36.6 10.1 41.3 25.5 61.2 77.6 2.9 42.3 30.2 84.5 166.2 22.5 62.6 72.3 1.4 10.6 32.9 24.6 23.9 23.6 9.7 19.5 55.0 45.4 29.0 0.9 27.3 47.5 148.9 37.9 165.7 92.4 23.4 23.0 42.5 30.6 2.5 182.2 292.7 11.2 177.7 9.4 16.8 8.4 10.7 264.3 12.9 7.4 14.5 431.8 28.4 202.6 22.9 7.3 92.3 32.4 44.5 13.9 57.7 58.3 8.0 19.2 12.2 19.4 0.9 17.1 30.0 3.1 3.2 20.5 24.2 23.9 11.9 33.3 28.2 23.9 51.6 25.1 19.7 6.2 35.8 30.8 25.8 8.4 25.4 10.2 78.6 45.0 32.4 38.8 37.3 13.5 3.2 37.8 30.5 219.1 56.3 53.5 24.0 45.9 39.7 132.2 35.2 3.6 11.4 49.8 1.7 118.5 50.8 28.5 59.6 152.9 28.3 14.3 80.0 30.2 54.4 121.7 14.9 10.3 53.3 70.7 50.9 57.9 13.2 28.6 28.7 47.9 55.7 39.0 6.4 13.1 13.8 25.2 50.4 53.8 23.6 10.4 95.0 19.3 10.3 52.8 33.2 PAK4 ENSG00000130669 "P21 (RAC1) activated kinase 4" O96013 19 39125770-39182816 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 154.7;MCF7: 172.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025747, CAB044670, HPA070175, HPA072220" Uncertain Supported "Plasma membrane,Cell Junctions" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Plasma membrane, Cell Junctions" "CAB025747: , CAB044670: AB_1854940, HPA070175: AB_2686232, HPA072220: AB_2686497" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (5.86e-2)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (8.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.13e-3)" "unprognostic (3.90e-2)" "unprognostic (4.04e-2)" "unprognostic (7.29e-2)" "prognostic unfavorable (9.85e-4)" "prognostic favorable (5.29e-5)" "unprognostic (2.39e-1)" "unprognostic (7.05e-2)" "unprognostic (2.02e-1)" "unprognostic (4.85e-2)" 11.6 20.0 16.7 8.1 18.2 5.3 22.1 14.2 18.4 27.2 14.0 30.2 27.4 20.6 9.4 43.9 23.4 7.5 15.5 13.9 13.4 37.2 26.2 39.6 4.5 17.1 17.2 24.2 31.8 16.2 30.5 16.3 15.8 40.7 8.0 5.8 42.4 11.0 14.0 40.4 25.1 5.7 12.0 13.8 25.3 35.0 15.7 5.4 29.3 4.3 5.4 20.2 30.4 17.0 62.8 154.7 22.7 34.8 7.1 7.5 68.1 29.3 11.7 19.3 19.4 102.1 51.9 14.3 43.3 18.7 25.2 22.7 12.6 23.2 7.2 38.0 35.4 16.9 27.5 50.4 11.3 17.5 23.6 9.0 10.2 18.1 12.9 12.6 25.5 21.4 34.3 11.0 11.8 172.7 18.6 18.9 41.4 55.2 36.7 18.5 17.9 10.9 19.0 67.9 72.2 49.9 29.8 130.6 33.6 11.7 58.1 28.4 42.8 32.6 55.6 37.8 53.0 12.3 12.9 11.9 39.9 10.3 39.9 0.3 0.7 1.2 0.6 0.3 0.8 0.5 0.7 1.1 0.9 0.6 0.5 0.5 0.5 0.9 0.6 0.8 0.9 0.7 16.7 18.2 14.2 18.4 13.9 13.4 17.1 17.2 15.8 12.0 15.7 17.0 5.1 0.0 1.5 9.4 3.9 14.4 15.9 13.8 9.6 18.8 34.2 21.7 2.0 20.0 9.1 18.4 25.0 42.6 4.4 47.5 31.3 20.5 4.1 19.5 8.5 15.0 44.9 5.0 3.9 19.7 67.4 8.8 23.9 23.3 5.7 21.6 10.0 13.3 9.6 21.9 4.2 33.8 28.5 5.3 4.1 6.4 11.8 3.6 7.2 8.4 11.2 13.6 8.2 9.5 13.5 21.8 44.2 10.5 5.8 21.7 39.5 14.4 13.7 13.4 0.0 8.5 7.5 10.4 24.0 20.1 18.8 65.4 6.0 22.3 33.9 24.3 PANX2 "hPANX2, PX2" ENSG00000073150 "Pannexin 2" Q96RD6 22 50170731-50180295 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 51.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.4;Excitatory neurons: 13.3;Hepatocytes: 10.7;Inhibitory neurons: 15.8;Muller glia cells: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.9" "Lineage enhanced" "Detected in single" "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "EFO-21: 10.3;HDLM-2: 16.7;Hep G2: 19.6;MCF7: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004624, HPA039117" Enhanced Supported "Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA004624: , HPA039117: AB_10805354" "unprognostic (1.00e-1)" "unprognostic (7.25e-2)" "unprognostic (2.72e-2)" "unprognostic (1.05e-1)" "unprognostic (3.01e-3)" "unprognostic (2.11e-2)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (1.56e-1)" "unprognostic (4.43e-2)" "unprognostic (3.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-9)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.00e-1)" "unprognostic (4.08e-1)" 1.0 0.8 4.4 0.5 4.4 1.6 1.0 8.4 40.1 1.7 0.0 0.3 0.0 1.2 0.5 5.2 2.2 0.4 0.7 8.0 13.1 3.0 9.6 2.1 0.0 51.0 8.8 3.4 1.4 0.3 7.9 0.1 48.4 3.9 0.0 1.6 5.0 1.4 0.7 1.1 0.2 0.0 7.9 1.9 0.4 1.7 14.1 0.0 7.3 0.1 0.1 1.4 1.9 16.4 0.9 2.1 0.4 2.3 0.0 0.2 4.9 2.6 2.5 0.5 0.4 0.5 8.0 0.0 10.3 0.3 1.4 0.5 1.3 1.0 0.1 16.7 1.4 0.4 3.5 19.6 0.7 0.1 1.2 0.2 1.0 0.7 0.0 1.1 0.6 0.0 1.4 0.0 0.2 10.8 0.0 1.0 3.9 0.0 4.2 1.0 0.0 4.0 0.0 1.6 9.8 0.9 1.6 0.2 6.5 0.5 0.7 0.8 4.5 0.5 4.1 6.7 4.9 1.8 0.1 0.6 0.3 0.0 7.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.6 0.0 0.0 4.4 4.4 8.4 40.1 8.0 13.1 51.0 8.8 48.4 7.9 14.1 16.4 0.0 0.0 1.1 7.2 0.3 0.5 3.1 0.6 0.0 11.4 2.5 2.4 0.8 1.5 2.6 0.0 0.0 0.0 1.5 0.0 5.9 2.3 0.3 5.9 1.5 0.7 0.0 0.4 13.3 2.8 0.2 0.8 0.0 7.0 0.0 2.1 0.0 10.7 0.1 0.0 15.8 0.0 0.0 0.9 1.5 0.2 0.0 1.1 0.0 1.9 1.8 29.7 0.0 6.6 1.2 1.8 0.0 1.2 0.5 6.0 0.0 3.0 3.0 3.6 0.0 0.1 0.9 0.0 1.8 0.3 0.3 0.0 0.2 0.1 0.0 4.5 PAQR8 "C6orf33, LMPB1, MPRB" ENSG00000170915 "Progestin and adipoQ receptor family member 8" Q8TEZ7 6 52361421-52407777 "Predicted membrane proteins, Transporters" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 144.9" "Cell type enhanced" "Detected in many" "Astrocytes: 168.5;Distal enterocytes: 154.3;Microglial cells: 74.0;Oligodendrocytes: 298.2;Paneth cells: 80.7;Proximal enterocytes: 100.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 41.8;OE19: 87.9;SuSa: 34.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064625 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA064625: AB_2685304" "prognostic favorable (4.61e-4)" "unprognostic (7.39e-3)" "unprognostic (2.77e-3)" "unprognostic (8.23e-2)" "unprognostic (4.33e-1)" "unprognostic (4.08e-3)" "unprognostic (2.66e-2)" "unprognostic (5.67e-2)" "unprognostic (6.37e-2)" "unprognostic (4.30e-3)" "unprognostic (2.10e-1)" "unprognostic (5.55e-2)" "unprognostic (8.82e-3)" "unprognostic (1.04e-1)" "unprognostic (2.12e-1)" "unprognostic (3.14e-2)" "prognostic favorable (6.40e-4)" 2.7 4.0 83.7 9.2 113.9 1.2 2.3 122.9 86.7 4.7 42.0 38.9 19.3 5.1 8.0 17.6 6.3 6.0 3.5 74.4 89.7 8.0 1.5 7.3 10.3 133.8 110.7 24.3 2.8 5.2 2.2 7.0 123.1 4.3 36.7 2.9 2.2 23.3 0.9 3.1 33.7 6.3 102.8 6.2 32.3 3.7 106.4 9.2 2.8 1.5 7.6 9.7 5.5 144.9 0.9 1.0 10.7 4.6 6.3 10.2 7.3 3.2 12.1 2.0 4.4 4.1 3.8 1.1 1.2 2.2 4.7 0.4 1.4 5.3 3.2 14.8 1.7 6.6 1.0 41.8 1.7 1.8 0.9 2.9 0.7 1.4 7.5 7.4 11.5 12.9 1.5 6.4 8.3 1.5 4.4 6.1 5.4 87.9 0.5 11.5 1.7 2.8 12.4 3.1 4.0 8.7 0.8 0.3 12.4 34.4 0.3 14.7 4.8 4.0 1.6 1.2 1.9 1.9 2.6 1.6 3.7 16.9 21.5 3.0 3.2 1.4 2.8 0.6 4.2 1.1 8.3 5.7 7.0 1.0 17.8 8.3 0.6 8.5 0.6 3.5 6.2 4.2 83.7 113.9 122.9 86.7 74.4 89.7 133.8 110.7 123.1 102.8 106.4 144.9 4.9 3.2 10.6 168.5 3.6 2.0 3.7 3.1 0.6 2.1 0.7 1.3 4.4 14.3 3.5 3.7 8.4 1.7 7.6 154.3 0.0 4.4 0.5 12.2 3.9 7.4 22.9 4.2 21.1 1.1 3.1 6.8 18.8 7.5 4.5 23.7 4.2 0.2 8.8 0.0 19.4 45.5 6.1 19.8 3.5 1.6 5.6 7.3 14.2 74.0 11.4 4.2 3.1 19.1 298.2 4.9 80.7 10.1 0.6 6.6 100.5 0.1 8.9 3.3 0.0 1.0 3.6 12.1 3.3 5.3 1.0 0.8 9.2 10.0 42.5 7.3 PARD3 "ASIP, Baz, Bazooka, PAR3, PARD3A, PPP1R118" ENSG00000148498 "Par-3 family cell polarity regulator" Q8TEW0 10 34109560-34815325 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 455.4;Inhibitory neurons: 147.0;Microglial cells: 193.0;Oligodendrocyte precursor cells: 367.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 50 "basophil: 9.6" "Lineage enriched" "Detected in single" 97 "granulocytes: 9.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030443 Approved Supported "Plasma membrane,Cell Junctions" NA NA 21000 "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cell Junctions" "HPA030443: AB_10600926" "unprognostic (9.49e-2)" "unprognostic (1.18e-1)" "unprognostic (1.62e-1)" "unprognostic (2.83e-2)" "unprognostic (1.81e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (3.48e-1)" "unprognostic (3.49e-1)" "unprognostic (8.07e-2)" "unprognostic (5.82e-3)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.20e-2)" "unprognostic (3.54e-1)" "unprognostic (9.20e-2)" "prognostic unfavorable (4.41e-4)" 13.1 15.9 19.6 4.8 17.0 0.5 21.5 10.9 12.4 25.9 16.0 30.4 10.6 20.7 12.2 47.8 20.6 14.9 14.6 17.8 20.6 25.1 22.1 15.2 2.6 15.7 22.1 38.5 34.2 20.7 7.3 21.7 15.9 17.0 21.7 13.6 20.1 23.9 40.5 52.1 13.4 21.8 16.0 4.2 17.7 14.0 24.0 13.5 15.2 30.9 12.4 21.3 30.8 13.9 50.6 121.1 40.1 28.6 28.5 24.2 59.1 22.2 25.4 37.3 40.0 44.3 43.3 0.3 31.4 44.6 30.4 35.8 34.7 56.7 46.1 0.4 26.8 0.0 14.9 44.1 36.2 5.7 0.1 28.7 54.9 50.9 38.1 35.9 23.3 32.4 34.7 14.9 44.8 35.4 59.3 4.2 18.0 32.7 41.4 44.9 39.0 21.9 80.9 38.4 20.1 20.9 26.8 37.3 42.9 49.6 21.1 6.7 28.4 18.7 56.1 35.5 24.2 13.2 17.1 0.1 21.0 0.2 22.3 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 19.6 17.0 10.9 12.4 17.8 20.6 15.7 22.1 15.9 16.0 24.0 13.9 6.4 35.3 35.3 455.4 0.2 34.0 42.3 19.8 19.9 8.7 17.1 24.9 39.0 21.5 24.3 14.7 29.2 24.9 0.2 25.6 0.0 34.1 19.9 22.3 29.9 9.4 24.0 2.7 5.4 36.4 25.0 22.3 13.3 33.4 1.3 33.1 8.9 24.8 3.4 11.8 147.0 30.1 14.2 0.6 4.7 20.3 30.4 7.7 5.4 193.0 0.8 28.8 1.0 367.9 13.9 38.8 23.8 38.4 1.4 31.4 13.7 25.6 29.3 19.7 26.3 23.4 26.1 6.2 27.6 40.4 61.5 40.1 1.5 32.1 22.0 47.2 PCDHA4 "CNR1, CNRN1, CRNR1, PCDH-ALPHA4" ENSG00000204967 "Protocadherin alpha 4" Q9UN74 5 140806929-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 2.0;granulocytes: 3.8;Respiratory ciliated cells: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.6;AF22: 5.6;EFO-21: 5.1;T-47d: 5.4" "Not detected" "Not detected" "HPA043180, HPA073478" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 6: Brain - Smell perception" "Cluster 38: EFO-21 - Unknown function" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Plasma membrane" Cytosol "HPA043180: AB_10806381, HPA073478: AB_2686608" "unprognostic (2.71e-3)" "unprognostic (1.16e-1)" "unprognostic (2.85e-1)" "unprognostic (5.32e-2)" "unprognostic (1.93e-1)" "unprognostic (3.14e-2)" "unprognostic (2.56e-1)" "unprognostic (7.90e-3)" "unprognostic (7.14e-3)" "unprognostic (7.00e-2)" "unprognostic (5.06e-3)" "unprognostic (6.94e-5)" "unprognostic (5.01e-3)" "unprognostic (6.21e-2)" "unprognostic (3.98e-1)" "unprognostic (6.29e-3)" "unprognostic (4.79e-2)" 0.2 0.2 0.9 0.2 1.2 0.9 0.4 2.9 1.1 0.5 0.0 0.3 0.3 0.6 0.4 0.1 0.3 1.3 0.1 0.9 0.5 0.4 0.1 0.4 0.3 0.6 0.5 0.2 1.2 0.1 0.4 0.1 0.6 0.4 0.2 0.9 0.2 0.3 0.3 0.5 0.2 0.3 0.3 0.3 0.3 0.4 0.4 0.1 0.3 0.1 0.2 0.2 0.1 1.5 0.1 6.6 5.6 0.2 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 1.1 0.1 5.1 0.1 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.2 0.4 0.2 0.1 0.2 0.3 0.3 1.1 0.1 0.1 0.3 0.3 0.2 0.1 0.7 0.1 0.1 0.1 0.2 1.7 1.2 0.9 0.1 0.1 0.2 0.1 0.2 0.2 2.3 0.0 1.4 0.5 0.8 5.4 0.1 0.6 1.2 0.8 0.5 0.1 0.3 0.1 0.1 0.2 0.2 0.5 0.3 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.9 1.2 2.9 1.1 0.9 0.5 0.6 0.5 0.6 0.3 0.4 1.5 0.1 3.2 2.0 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.2 0.0 0.8 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.3 0.6 0.7 0.4 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.3 3.8 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.2 2.9 1.1 0.0 0.4 0.5 1.0 0.5 0.0 0.0 0.0 0.2 0.1 0.1 0.4 PCDHGB2 PCDH-GAMMA-B2 ENSG00000253910 "Protocadherin gamma subfamily B, 2" Q9Y5G2 5 141360042-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.2;Cardiomyocytes: 1.4;Endometrial stromal cells: 1.0;Fibroblasts: 1.2" "Cancer enriched" "Detected in many" 5 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.5;ASC TERT1: 9.8;LHCN-M2: 8.2;REH: 7.8" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077526" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane, Cytosol" Nucleoplasm "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077526: AB_2732350" "unprognostic (7.14e-3)" "unprognostic (8.79e-3)" "unprognostic (3.21e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.67e-4)" "unprognostic (1.10e-2)" "unprognostic (2.19e-4)" "unprognostic (2.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.78e-1)" "unprognostic (1.05e-1)" "unprognostic (8.46e-3)" "unprognostic (4.59e-2)" "unprognostic (2.57e-1)" "unprognostic (3.06e-2)" "unprognostic (1.29e-1)" "unprognostic (3.36e-4)" 1.5 1.0 2.6 0.6 3.6 0.1 1.1 6.3 2.8 2.1 0.0 1.1 0.2 3.0 0.9 0.9 1.6 1.9 1.8 3.1 3.2 0.7 0.7 1.7 0.3 3.7 3.3 2.8 0.8 1.2 0.9 1.1 3.6 1.3 0.8 1.6 0.8 1.2 0.8 0.8 0.5 1.5 3.0 0.6 0.6 0.5 2.2 0.4 0.7 0.9 0.3 0.9 1.1 5.5 0.1 0.3 2.0 0.2 13.5 9.8 0.1 2.1 2.9 0.6 3.2 0.0 0.3 3.7 1.0 1.7 7.1 0.5 0.4 0.3 1.0 0.0 0.2 0.0 0.3 0.4 0.5 0.2 0.2 2.5 0.5 0.2 0.1 4.7 1.7 0.1 0.2 1.2 8.2 0.5 2.9 0.7 0.1 0.9 0.9 7.8 2.6 0.2 0.2 0.3 1.5 1.6 0.2 0.4 0.4 1.5 3.0 0.2 5.9 2.9 0.6 4.4 3.9 0.2 2.2 0.6 3.1 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.6 6.3 2.8 3.1 3.2 3.7 3.3 3.6 3.0 2.2 5.5 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.6 2.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 PDE4A DPDE2 ENSG00000065989 "Phosphodiesterase 4A" P27815 19 10416773-10469630 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 190.8;Late spermatids: 197.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 36.5;NB-4: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017632, HPA043310, HPA076091" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB017632: AB_1127109, HPA043310: AB_2678419, HPA076091: AB_2686775" "unprognostic (1.29e-2)" "unprognostic (3.98e-2)" "unprognostic (8.91e-2)" "unprognostic (1.82e-1)" "unprognostic (7.00e-2)" "unprognostic (6.84e-2)" "unprognostic (1.54e-2)" "unprognostic (4.39e-2)" "unprognostic (7.91e-2)" "unprognostic (1.52e-2)" "unprognostic (6.90e-2)" "unprognostic (2.41e-1)" "unprognostic (2.27e-2)" "unprognostic (1.64e-2)" "unprognostic (2.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.15e-1)" 13.7 5.6 10.9 5.9 12.5 5.4 9.7 3.0 32.3 12.4 0.0 11.0 2.7 9.8 1.4 4.1 7.5 6.6 12.5 11.8 7.9 7.0 2.5 13.0 3.2 21.9 7.1 1.5 12.7 22.2 3.9 6.5 20.8 8.4 4.0 5.3 9.8 4.8 37.9 5.4 6.5 6.2 1.1 8.2 12.9 24.5 13.0 1.6 11.0 16.9 2.6 8.2 8.2 15.7 0.1 2.5 0.5 6.7 18.7 11.1 3.7 5.6 11.1 0.7 1.9 6.0 5.4 2.6 16.1 14.6 0.4 0.6 3.9 0.7 0.4 6.7 5.5 23.7 8.1 6.7 12.3 3.9 36.5 8.3 0.8 6.2 0.0 0.7 5.3 2.1 18.9 5.5 4.0 1.7 2.3 43.3 2.9 6.7 4.7 15.6 3.7 20.3 0.9 1.4 4.2 1.5 0.4 0.2 6.2 1.0 0.8 7.8 11.2 8.3 10.5 5.7 3.7 10.9 0.9 12.4 3.5 0.3 6.7 4.1 1.7 3.4 0.8 2.5 0.4 0.1 0.3 1.1 2.0 0.0 0.0 0.4 0.1 3.0 2.7 0.1 0.7 1.1 10.9 12.5 3.0 32.3 11.8 7.9 21.9 7.1 20.8 1.1 13.0 15.7 9.4 3.2 11.6 6.2 10.8 10.1 2.6 2.5 1.8 25.6 6.4 4.3 7.7 8.6 5.5 9.2 0.0 0.5 58.9 7.1 0.0 3.1 48.9 2.1 20.7 8.6 0.0 1.7 39.4 12.9 4.8 12.1 7.1 3.6 31.8 0.3 10.4 0.9 10.2 55.5 43.5 5.1 6.1 22.1 190.8 197.0 17.4 53.9 14.2 12.2 15.4 1.2 22.6 12.5 1.5 12.3 3.8 18.0 27.0 3.0 0.1 0.2 6.9 3.6 6.6 9.0 10.2 8.6 8.5 0.5 8.1 0.4 37.0 1.0 6.8 1.3 PDE4D DPDE3 ENSG00000113448 "Phosphodiesterase 4D" Q08499 5 58969038-60522120 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 74.9;skeletal muscle: 70.4" "Cell type enhanced" "Detected in many" "Astrocytes: 619.3;Excitatory neurons: 2969.7;Inhibitory neurons: 1116.9;Oligodendrocyte precursor cells: 848.0;Oligodendrocytes: 443.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "eosinophil: 57.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 57.9" "Cell line enhanced" "Detected in many" "A549: 62.2;AN3-CA: 70.4;HeLa: 104.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045895 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Cytosol "HPA045895: AB_10960275" "unprognostic (1.14e-1)" "unprognostic (8.73e-3)" "unprognostic (4.35e-2)" "unprognostic (7.87e-2)" "unprognostic (5.97e-2)" "unprognostic (2.03e-1)" "unprognostic (8.10e-4)" "unprognostic (1.17e-1)" "unprognostic (6.59e-2)" "unprognostic (1.84e-1)" "unprognostic (2.71e-1)" "unprognostic (2.65e-1)" "prognostic favorable (4.00e-5)" "unprognostic (1.51e-1)" "unprognostic (8.20e-2)" "unprognostic (1.77e-2)" "unprognostic (2.56e-2)" 8.9 1.3 3.3 9.8 9.9 74.9 4.6 0.0 11.3 5.3 0.0 21.0 5.5 7.4 18.4 13.7 7.3 9.1 15.7 4.4 4.2 17.2 2.8 13.3 5.3 7.0 2.0 3.0 3.7 5.5 6.7 16.6 1.2 19.9 15.0 21.4 7.4 21.2 70.4 4.5 7.0 15.3 0.8 4.0 10.3 3.4 3.8 8.6 7.4 34.4 5.6 22.0 8.2 5.7 0.1 62.2 12.8 70.4 2.3 4.4 10.1 1.6 1.8 3.4 4.9 24.5 2.0 4.8 0.2 0.5 10.3 10.6 0.0 2.8 5.9 2.9 7.0 9.2 104.6 5.3 9.1 4.4 0.7 9.3 2.3 9.6 1.7 1.1 7.3 0.3 0.0 1.6 5.9 4.5 3.6 10.3 2.4 1.8 3.2 1.2 16.0 10.5 15.9 23.5 2.3 8.0 16.4 27.1 14.2 11.4 1.9 9.3 8.5 0.9 0.2 12.0 3.3 3.5 0.1 0.5 10.3 17.3 2.7 4.2 2.0 57.9 1.5 0.1 1.5 11.0 1.4 0.7 1.4 11.3 0.9 0.7 3.1 0.4 0.2 0.0 0.8 1.1 3.3 9.9 0.0 11.3 4.4 4.2 7.0 2.0 1.2 0.8 3.8 5.7 22.5 32.1 110.0 619.3 32.3 10.6 30.1 6.6 35.3 20.2 5.1 2.7 35.7 8.6 30.2 42.3 73.0 11.3 118.6 28.1 11.7 0.6 21.4 19.0 8.6 16.9 33.4 2.1 2969.7 1.8 25.7 27.5 40.2 21.9 22.2 0.3 17.2 0.8 5.2 1.7 1116.9 18.2 6.1 4.8 11.1 36.6 1.5 29.5 10.6 407.5 6.0 12.0 29.9 848.0 443.3 8.2 11.9 4.9 44.4 43.3 8.9 27.5 19.4 52.8 0.0 64.0 6.3 1.1 7.7 40.6 8.8 3.1 94.3 1.1 11.7 26.5 PDE9A ENSG00000160191 "Phosphodiesterase 9A" O76083 21 42653621-42775509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 74.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 90.8;Paneth cells: 105.3;Proximal enterocytes: 233.5" "Cancer enriched" "Detected in all" 5 "prostate cancer: 31.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 29.7;EFO-21: 30.0;MCF7: 23.2;NB-4: 34.7;NTERA-2: 41.2;SCLC-21H: 22.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011380, HPA011978" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 45: Enterocytes - Digestion" Cytosol "Nucleoplasm, Plasma membrane" "HPA011380: AB_1855132, HPA011978: " "unprognostic (5.75e-2)" "unprognostic (9.92e-3)" "unprognostic (3.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (5.06e-2)" "unprognostic (3.99e-2)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (1.25e-2)" "unprognostic (5.01e-2)" "unprognostic (1.90e-2)" "unprognostic (4.01e-3)" "unprognostic (1.97e-1)" "unprognostic (6.55e-2)" "unprognostic (1.79e-1)" 9.4 11.1 12.3 3.9 15.1 0.5 10.8 14.0 12.9 7.2 8.6 74.7 2.9 5.1 19.4 3.7 10.6 6.8 4.3 10.6 12.6 29.8 4.2 4.9 4.8 12.4 14.4 3.5 4.1 6.5 9.9 10.3 12.7 38.5 16.4 10.7 12.7 15.8 2.4 7.0 47.3 8.8 11.0 18.3 13.4 1.9 15.0 7.8 6.5 4.8 3.1 18.9 6.2 12.0 0.0 2.8 29.7 3.7 0.0 0.8 0.5 0.0 0.0 0.0 0.0 3.2 18.2 0.0 30.0 0.0 2.2 0.0 2.7 9.8 0.0 0.0 10.4 0.0 0.0 6.4 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.5 0.0 0.0 23.2 1.5 34.7 41.2 14.6 0.0 0.0 0.0 1.2 20.4 7.6 22.5 13.5 5.2 0.0 0.5 7.0 0.2 19.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.2 0.1 0.2 3.1 0.6 0.4 0.9 0.0 0.4 1.0 0.3 12.3 15.1 14.0 12.9 10.6 12.6 12.4 14.4 12.7 11.0 15.0 12.0 18.6 3.2 5.0 43.4 1.6 1.0 10.9 4.2 6.2 26.4 13.4 12.6 1.6 5.7 2.4 18.4 0.0 0.0 1.0 90.8 29.4 7.3 0.6 18.1 8.5 11.9 13.1 3.2 5.6 2.4 0.1 5.9 1.5 26.8 1.3 6.1 5.7 0.9 7.5 35.3 10.8 25.8 8.2 1.3 0.8 2.2 11.8 1.6 28.4 31.9 1.1 11.0 0.0 29.1 16.6 5.3 105.3 6.0 0.2 28.1 233.5 8.9 1.3 2.8 13.1 0.5 6.4 0.4 2.3 0.5 0.6 0.4 3.8 16.9 24.4 15.0 PDGFC "fallotein, SCDGF" ENSG00000145431 "Platelet derived growth factor C" Q9NRA1 4 156760454-156971799 "Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 20.3" "Cell type enhanced" "Detected in many" "Astrocytes: 98.6;Granulosa cells: 124.1;Microglial cells: 85.3;Oligodendrocyte precursor cells: 233.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 60.0;hTERT-RPE1: 56.8;U-138 MG: 41.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009134 Approved Supported "Plasma membrane,Cytosol" "Secreted to blood" NA NA 37000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "HPA009134: AB_10601981" "unprognostic (3.12e-1)" "unprognostic (1.91e-2)" "unprognostic (5.79e-2)" "unprognostic (3.67e-2)" "unprognostic (3.97e-1)" "unprognostic (3.41e-2)" "unprognostic (8.78e-2)" "unprognostic (1.60e-2)" "unprognostic (1.36e-1)" "unprognostic (8.12e-2)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" "prognostic favorable (1.35e-5)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.25e-1)" "unprognostic (1.19e-2)" "prognostic unfavorable (3.17e-4)" 4.8 4.0 0.9 1.3 1.0 0.6 7.5 0.4 1.0 9.2 0.7 2.3 2.0 9.9 2.1 3.3 6.7 4.8 2.6 1.0 0.8 5.5 5.1 3.1 1.1 0.8 0.7 7.7 4.3 20.3 0.4 4.5 0.7 8.7 2.0 0.7 8.4 7.0 1.2 1.6 2.8 9.4 0.9 1.3 2.8 0.9 1.1 2.0 6.5 1.2 1.0 3.2 1.2 1.0 2.5 3.7 38.6 25.4 7.0 13.4 1.0 21.5 21.5 12.0 16.1 2.2 9.4 0.0 3.8 60.0 9.2 2.6 10.8 13.4 16.5 0.0 5.0 25.5 3.2 2.4 18.3 3.9 0.3 14.2 6.6 30.6 21.7 56.8 6.0 0.1 0.1 0.1 30.2 0.1 0.0 0.0 0.4 0.0 1.7 0.0 8.1 0.0 22.5 0.9 0.0 0.0 0.0 0.2 0.4 6.0 3.1 1.3 28.3 41.7 0.4 10.9 17.3 0.0 0.0 0.0 16.1 0.0 1.6 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.9 1.0 0.4 1.0 1.0 0.8 0.8 0.7 0.7 0.9 1.1 1.0 2.4 6.4 14.2 98.6 0.7 49.6 22.7 12.4 25.0 2.0 14.7 13.6 16.8 58.6 7.8 12.9 0.0 0.6 3.4 0.5 0.0 15.4 30.5 6.9 15.0 7.3 0.0 5.5 64.4 7.1 0.3 18.6 8.2 11.4 1.3 124.1 10.0 15.9 13.0 0.0 32.1 2.1 4.1 34.4 21.6 23.8 5.3 32.1 10.6 85.3 14.2 6.3 0.0 233.2 3.0 18.0 0.5 23.0 1.4 8.7 2.4 18.6 3.5 0.5 6.6 34.8 18.2 0.7 2.9 3.4 13.5 0.5 0.9 13.8 2.1 4.8 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 190.2" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 423.9;Fibroblasts: 256.4;Leydig cells: 449.8;Oligodendrocyte precursor cells: 499.6;Peritubular cells: 408.9" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 468.1;ASC TERT1: 216.1;BJ hTERT+: 279.4;fHDF/TERT166: 195.9;HHSteC: 156.3;HSkMC: 392.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 300000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 46.0 28.9 13.9 40.4 13.7 1.6 40.1 8.1 12.8 50.8 18.1 37.7 22.4 44.3 21.8 22.5 50.9 38.5 32.1 11.9 11.0 26.5 16.0 37.9 8.5 16.7 11.9 190.2 13.4 3.0 3.7 62.7 15.1 15.0 35.2 5.3 16.6 18.9 9.6 14.8 31.3 48.1 12.1 46.2 29.4 13.6 8.9 7.6 16.5 41.9 7.2 63.9 38.0 20.0 0.1 0.0 1.0 0.8 468.1 216.1 0.5 25.4 279.4 0.1 0.7 67.6 0.5 0.5 0.5 195.9 0.8 0.6 19.6 0.2 0.1 2.6 1.0 0.7 0.7 1.2 156.3 0.3 0.4 392.0 0.0 31.4 0.0 5.4 0.0 0.7 0.6 0.9 1.1 0.1 0.4 1.2 3.5 0.3 1.1 0.5 0.1 0.1 0.0 0.4 0.6 37.9 0.0 0.5 0.2 2.0 0.7 0.1 0.8 84.9 3.2 93.9 0.2 0.4 0.1 0.8 2.6 0.1 2.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.9 13.7 8.1 12.8 11.9 11.0 16.7 11.9 15.1 12.1 8.9 20.0 11.1 0.0 0.5 0.3 0.6 17.1 0.6 2.4 1.2 5.5 4.3 3.2 4.8 0.0 0.8 0.0 0.0 1.4 0.9 0.1 1.9 4.2 2.2 11.7 423.9 5.7 0.0 0.0 1.1 6.7 2.0 256.4 5.1 9.0 0.0 2.6 26.0 1.0 3.1 0.0 19.5 0.2 10.2 0.6 27.3 17.2 449.8 5.4 23.2 39.4 4.7 17.5 0.0 499.6 0.4 20.0 0.0 408.9 0.2 0.9 0.0 0.1 0.5 0.6 0.0 25.7 13.9 1.0 3.4 8.1 15.8 1.4 2.5 49.6 0.0 1.0 PDPN "aggrus, Gp38, GP40, PA2.26, T1A-2" ENSG00000162493 Podoplanin Q86YL7 1 13583465-13617957 "Predicted membrane proteins" "Cell shape" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 135.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 105.8;Basal respiratory cells: 98.5;Fibroblasts: 123.1;monocytes: 116.3;Muller glia cells: 97.7;Peritubular cells: 62.8" "Group enriched" "Detected in many" 4 "glioma: 83.2;head and neck cancer: 40.2;testis cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 149.5;EFO-21: 356.4;HAP1: 253.3;HHSteC: 216.0;NTERA-2: 116.0;SuSa: 119.0;TIME: 242.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007534, HPA007949, CAB008376" Enhanced Supported "Plasma membrane,Cell Junctions,Mitochondria" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "Cell Junctions, Mitochondria" "CAB008376: AB_592530, HPA007534: AB_1857718, HPA007949: " "unprognostic (1.75e-1)" "unprognostic (3.19e-2)" "unprognostic (6.03e-2)" "unprognostic (3.61e-2)" "unprognostic (2.73e-2)" "unprognostic (1.05e-2)" "unprognostic (3.85e-2)" "unprognostic (5.23e-2)" "unprognostic (9.21e-2)" "unprognostic (1.29e-1)" "unprognostic (1.13e-2)" "unprognostic (1.92e-2)" "unprognostic (5.62e-3)" "unprognostic (9.20e-3)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" "unprognostic (2.78e-2)" 61.5 3.3 8.9 55.9 9.3 0.0 20.9 13.7 8.1 43.1 23.5 16.6 3.8 25.9 11.3 15.8 33.4 42.1 20.3 8.0 14.6 3.4 0.6 32.4 9.8 24.9 15.6 29.4 6.4 1.1 3.3 135.6 19.1 14.0 10.6 22.7 9.1 14.1 30.0 20.0 15.9 34.5 16.4 0.3 24.7 4.5 22.5 10.3 6.2 11.3 18.5 96.1 25.2 21.2 0.1 0.0 149.5 0.1 0.5 0.0 0.1 2.4 0.1 0.0 0.0 0.0 0.1 0.2 356.4 9.0 0.1 0.7 253.3 44.7 0.0 1.0 46.1 0.1 0.0 0.0 216.0 0.0 0.2 29.5 82.9 18.6 21.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 116.0 0.0 0.6 0.3 0.2 0.1 0.0 4.0 0.1 0.1 0.2 0.0 0.3 119.0 0.1 0.6 242.2 41.8 34.6 0.6 0.1 0.1 0.3 1.0 88.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.9 9.3 13.7 8.1 8.0 14.6 24.9 15.6 19.1 16.4 22.5 21.2 2.4 105.8 11.2 3.9 0.2 14.5 30.4 98.5 14.8 1.4 0.5 19.9 8.4 2.8 18.8 0.0 4.2 2.0 0.1 0.0 0.0 0.5 0.7 1.6 37.6 22.4 0.0 0.0 2.6 0.0 2.1 123.1 0.0 2.8 1.3 3.4 6.4 0.0 6.5 0.0 3.5 0.0 8.2 0.0 14.0 1.8 20.2 5.3 7.2 5.6 116.3 97.7 0.0 19.6 0.2 0.4 0.0 62.8 0.0 15.8 0.0 0.0 5.4 3.4 0.0 17.0 8.4 1.0 8.2 3.9 7.0 2.9 1.3 0.9 0.0 3.4 PDZD2 "KIAA0300, PDZK3" ENSG00000133401 "PDZ domain containing 2" O15018 5 31639131-32110932 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.8" "Cell type enhanced" "Detected in many" "Early spermatids: 232.9;Excitatory neurons: 313.2;Oligodendrocyte precursor cells: 745.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 24.8;cerebral cortex: 15.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.1;EFO-21: 4.5;SiHa: 11.6;SK-BR-3: 10.6;T-47d: 5.5" "Low region specificity" "Detected in all" "CAB020784, HPA036503, HPA036504, HPA064387, HPA076072" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "CAB020784: , HPA036503: AB_2675161, HPA036504: , HPA064387: AB_2685252, HPA076072: " "unprognostic (3.65e-2)" "unprognostic (4.06e-2)" "unprognostic (6.63e-2)" "unprognostic (5.42e-5)" "unprognostic (2.39e-1)" "unprognostic (9.67e-3)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (3.38e-2)" "unprognostic (2.45e-2)" "unprognostic (1.71e-2)" "unprognostic (1.93e-1)" "unprognostic (2.33e-3)" "unprognostic (4.13e-2)" "unprognostic (6.92e-2)" "unprognostic (7.67e-2)" "unprognostic (1.79e-1)" 16.5 0.9 4.5 0.7 24.8 0.1 5.0 0.7 15.7 2.2 10.6 1.4 0.5 2.5 1.9 5.3 2.2 0.9 18.8 4.7 0.3 8.2 0.1 9.0 0.3 4.5 4.3 14.4 1.2 0.6 1.8 10.9 1.0 1.5 0.7 14.8 1.6 1.9 2.5 10.1 0.6 2.4 0.3 0.2 1.7 5.6 4.1 2.6 1.0 4.8 1.7 0.6 2.1 0.0 0.1 0.0 3.1 0.1 0.0 0.0 8.1 0.0 0.0 0.6 0.5 0.0 0.0 0.0 4.5 0.0 1.2 4.3 1.7 0.9 0.0 0.0 0.2 0.0 2.6 0.0 0.0 0.0 2.2 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.7 0.0 0.0 0.0 3.5 0.0 0.1 0.7 11.6 10.6 0.0 2.6 5.5 0.0 0.0 0.0 2.2 0.0 0.5 0.0 0.0 2.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 24.8 0.7 15.7 4.7 0.3 4.5 4.3 1.0 0.3 4.1 0.0 26.2 44.8 38.6 39.2 0.2 16.8 4.4 14.0 13.6 7.0 10.6 6.9 53.9 0.0 9.3 5.5 98.0 25.5 1.9 0.1 0.0 0.2 232.9 9.7 16.9 14.7 0.0 1.3 313.2 0.2 3.4 8.6 7.7 33.2 1.3 18.7 5.7 0.2 2.2 15.2 113.2 0.0 4.1 0.3 3.1 55.2 7.5 1.0 7.2 87.1 0.2 6.4 0.0 745.0 104.7 3.5 0.0 10.5 0.1 3.5 0.0 8.2 2.8 62.1 46.0 7.3 13.4 12.3 3.8 15.1 18.5 21.1 1.3 46.8 0.0 1.8 PHLDB2 "FLJ21791, LL5b, LL5beta" ENSG00000144824 "Pleckstrin homology like domain family B member 2" Q86SQ0 3 111732497-111976517 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 249.9;Basal prostatic cells: 189.9;Suprabasal keratinocytes: 114.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 103.8;HaCaT: 105.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035146, HPA035147" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA035146: AB_10600927, HPA035147: AB_2674492" "unprognostic (2.83e-2)" "unprognostic (4.93e-3)" "unprognostic (2.15e-2)" "unprognostic (8.01e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.59e-4)" "unprognostic (5.14e-2)" "unprognostic (2.20e-2)" "unprognostic (1.43e-1)" "unprognostic (9.03e-2)" "unprognostic (2.00e-2)" "unprognostic (3.53e-1)" "prognostic favorable (7.03e-8)" "unprognostic (3.24e-3)" "unprognostic (3.47e-2)" "unprognostic (1.53e-1)" "unprognostic (2.83e-1)" 25.6 7.2 2.2 15.7 2.3 1.5 11.3 0.9 4.0 10.6 10.3 29.0 6.0 20.4 7.4 11.1 13.3 15.3 42.7 0.9 0.5 31.5 35.6 17.6 5.1 1.2 1.8 8.9 10.0 1.8 5.7 40.8 1.6 16.4 8.6 0.5 10.6 25.7 4.8 7.0 7.7 24.3 1.6 16.5 11.7 2.8 3.9 5.0 6.2 8.7 3.2 26.5 10.5 2.0 103.8 11.2 62.2 0.1 19.8 32.3 25.5 58.3 28.5 37.8 44.5 32.1 7.5 0.0 59.6 22.6 38.2 105.2 0.9 37.5 68.6 1.6 1.5 0.0 26.1 10.6 21.3 0.2 0.3 38.1 21.9 26.1 48.1 42.5 61.8 1.0 0.1 0.4 11.5 0.2 4.2 0.1 25.3 1.0 19.3 9.0 80.1 0.0 22.2 24.5 1.6 4.7 57.6 1.1 5.9 34.1 2.1 0.3 54.4 10.2 85.2 27.4 14.3 5.4 0.2 0.2 10.4 0.1 19.9 0.1 0.0 0.0 2.6 0.0 1.8 0.2 1.8 2.9 0.0 0.4 0.0 1.1 0.2 1.0 0.0 0.5 0.4 0.8 2.2 2.3 0.9 4.0 0.9 0.5 1.2 1.8 1.6 1.6 3.9 2.0 30.9 80.1 7.5 2.6 1.6 249.9 189.9 33.3 33.0 0.2 11.6 9.8 95.8 25.8 16.8 33.1 2.1 27.0 13.0 0.6 23.5 62.6 12.9 3.7 15.3 44.8 10.8 2.7 51.7 20.5 51.5 40.3 14.3 26.2 7.0 1.2 35.3 35.2 3.5 0.0 9.5 3.4 8.2 2.5 20.6 5.3 14.3 2.9 23.2 39.4 1.0 0.1 23.7 4.5 1.8 45.4 0.5 22.6 2.8 60.1 0.0 30.9 6.8 0.3 13.1 21.0 95.9 0.5 3.3 17.7 114.7 66.8 6.7 2.7 1.9 84.0 PIK3CG ENSG00000105851 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma" P48736 7 106865278-106908980 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Endocytosis, Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 43.6;lymphoid tissue: 19.7" "Cell type enhanced" "Detected in some" "B-cells: 24.9;dendritic cells: 26.5;Early spermatids: 28.9;granulocytes: 20.8;monocytes: 23.8;NK-cells: 25.7;Plasma cells: 88.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 29.4;HL-60: 28.8;HMC-1: 34.9;Karpas-707: 29.1;MOLT-4: 56.0;U-266/70: 71.4;U-937: 52.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069976 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" Cytosol "HPA069976: AB_2686224" "unprognostic (8.34e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (1.71e-2)" "unprognostic (3.20e-2)" "unprognostic (3.82e-3)" "unprognostic (3.02e-1)" "unprognostic (6.77e-2)" "unprognostic (1.16e-1)" "unprognostic (7.06e-3)" "unprognostic (1.15e-1)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (9.08e-2)" "unprognostic (1.23e-1)" "unprognostic (5.38e-1)" "unprognostic (5.24e-2)" 3.1 1.8 0.5 11.5 0.6 43.6 1.9 0.8 1.3 1.9 1.3 4.2 4.1 1.3 0.5 1.7 1.4 3.2 1.6 0.5 1.0 1.0 2.0 4.9 19.0 2.5 1.3 1.6 0.3 0.7 0.2 2.9 2.7 1.0 3.8 0.1 1.3 0.9 0.3 0.8 4.3 2.7 1.8 11.0 4.0 5.2 2.0 16.4 1.1 1.0 19.7 4.3 0.2 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 2.7 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 17.9 0.0 0.0 0.0 28.8 34.9 0.0 0.0 0.0 0.0 0.0 11.0 16.9 20.6 29.1 0.0 0.0 56.0 17.6 0.0 0.0 0.0 14.6 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.6 2.9 0.1 0.2 0.1 0.0 71.4 0.0 27.3 0.1 52.1 6.7 10.8 6.0 24.3 8.8 17.8 8.1 7.3 4.1 6.7 9.4 10.2 4.2 5.9 22.7 9.8 43.7 8.6 4.4 6.8 0.5 0.6 0.8 1.3 0.5 1.0 2.5 1.3 2.7 1.8 2.0 3.9 1.5 0.0 1.8 0.3 24.9 0.8 0.0 0.0 0.6 0.0 0.1 0.1 0.5 0.0 0.6 0.0 0.0 0.0 26.5 0.2 0.0 0.0 28.9 0.1 0.2 1.7 0.0 7.8 5.5 0.0 0.0 0.1 3.6 0.1 20.8 0.4 2.5 0.5 6.8 0.0 0.3 0.0 0.0 11.9 8.3 18.8 0.6 18.9 7.2 15.0 23.8 0.0 25.7 0.0 0.2 0.0 0.0 0.0 88.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 6.6 3.7 0.2 0.3 0.1 18.1 0.6 0.6 0.1 PIP4K2A "PIP5K2A, PIP5KIIA, PIP5KIIalpha" ENSG00000150867 "Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha" P48426 10 22534854-22714578 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 498.1" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1585.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065440, HPA068771" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 4900000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Plasma membrane, Cytosol" "HPA065440: AB_2685490, HPA068771: AB_2686030" "unprognostic (1.11e-1)" "unprognostic (2.71e-3)" "unprognostic (1.57e-3)" "unprognostic (4.20e-3)" "unprognostic (1.55e-1)" "unprognostic (8.80e-3)" "unprognostic (1.56e-3)" "unprognostic (7.32e-2)" "unprognostic (1.68e-1)" "unprognostic (7.08e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.46e-4)" "unprognostic (1.52e-3)" "unprognostic (2.51e-1)" "unprognostic (1.38e-1)" "unprognostic (7.92e-3)" 28.4 15.5 162.5 47.8 329.4 44.8 15.0 239.0 239.9 26.5 49.8 17.8 13.2 21.1 11.8 19.8 15.2 32.9 13.5 169.7 193.6 16.5 18.6 25.9 81.2 260.6 273.4 8.8 10.9 24.8 8.5 23.7 271.7 9.3 19.1 15.3 7.8 13.0 5.1 8.3 20.6 31.5 171.8 62.6 19.3 12.5 233.3 60.4 12.8 10.9 88.5 24.1 10.5 498.1 30.2 29.2 33.4 10.8 52.3 70.6 25.3 55.0 58.1 29.1 35.7 27.6 47.2 63.2 19.4 111.0 63.7 10.4 29.2 15.4 29.2 140.5 30.4 118.7 21.6 60.9 92.5 23.1 89.1 35.6 13.7 39.7 38.2 44.6 43.7 83.5 67.4 119.1 54.5 12.5 92.3 20.5 13.7 14.5 20.7 36.9 47.8 86.3 43.0 5.8 6.1 13.9 17.7 9.0 86.4 37.6 7.6 39.1 53.0 22.3 32.8 41.7 33.9 75.1 46.3 45.0 60.5 68.3 17.6 72.6 32.6 104.0 119.5 57.9 164.0 52.1 94.2 139.9 43.7 33.1 62.8 118.2 40.5 144.2 67.3 44.8 75.9 183.4 162.5 329.4 239.0 239.9 169.7 193.6 260.6 273.4 271.7 171.8 233.3 498.1 22.5 3.2 6.7 84.9 43.2 17.6 4.0 2.0 3.4 5.7 12.9 5.5 8.1 14.3 5.6 18.4 2.1 8.6 196.9 3.4 11.7 9.7 22.9 7.4 15.7 29.2 4.9 236.9 65.6 10.7 5.4 19.6 6.6 24.8 22.8 13.4 62.4 8.7 31.8 13.5 62.0 2.9 0.0 98.6 80.0 34.5 16.8 82.8 104.9 142.4 81.3 5.0 159.6 167.9 1585.0 22.1 3.7 10.1 36.4 7.1 1.0 15.6 2.2 9.1 19.7 14.1 30.6 6.1 7.9 3.3 16.9 12.4 130.7 8.5 2.8 6.6 PIP5K1A ENSG00000143398 "Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha" Q99755 1 151197949-151249536 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029366 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "HPA029366: AB_10602116" "unprognostic (1.05e-1)" "unprognostic (2.36e-2)" "unprognostic (8.64e-2)" "unprognostic (7.94e-3)" "unprognostic (1.17e-1)" "unprognostic (3.28e-2)" "unprognostic (1.26e-2)" "unprognostic (3.01e-1)" "unprognostic (8.79e-2)" "unprognostic (1.15e-1)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.16e-7)" "unprognostic (1.44e-1)" "unprognostic (8.14e-2)" "unprognostic (2.93e-1)" "unprognostic (1.59e-1)" 20.1 19.1 16.0 16.1 17.3 9.7 19.5 17.8 19.2 18.9 20.8 17.2 16.2 18.8 21.1 20.4 18.9 19.7 19.8 16.8 17.3 21.9 18.6 21.8 18.7 15.1 15.7 18.7 13.6 23.0 21.5 25.9 14.7 16.7 15.1 30.1 16.9 14.1 29.2 21.0 16.9 20.3 14.2 19.0 16.6 35.1 16.9 24.7 18.4 25.4 20.1 20.5 17.4 18.4 49.3 37.4 57.7 67.6 37.5 38.8 56.7 63.5 89.3 116.6 103.7 68.7 46.8 43.9 66.8 67.9 52.7 42.0 75.7 42.6 101.2 68.8 54.0 36.0 48.4 33.9 70.1 64.9 43.8 51.1 40.3 72.7 90.7 52.1 48.8 69.4 35.6 36.7 60.4 69.9 63.6 32.4 86.0 38.2 58.3 60.5 50.7 34.1 61.2 27.1 38.6 49.4 87.1 66.6 57.4 96.4 69.2 59.4 47.4 46.6 64.7 42.6 77.0 50.5 93.6 99.3 44.7 18.6 56.6 0.1 3.9 5.7 3.7 4.7 2.8 6.6 3.3 4.1 6.4 3.0 3.7 2.9 8.9 3.9 3.8 6.7 3.1 4.7 16.0 17.3 17.8 19.2 16.8 17.3 15.1 15.7 14.7 14.2 16.9 18.4 11.6 32.1 12.2 43.8 21.3 66.2 23.2 17.0 39.9 34.1 31.3 22.0 18.4 17.2 15.3 31.3 98.0 25.9 18.3 12.7 9.8 13.5 4.9 64.0 26.2 15.6 6.0 12.4 59.6 8.7 29.3 19.8 19.4 71.0 12.0 19.9 14.3 14.3 12.8 26.9 51.2 9.7 18.3 10.7 29.5 4.8 13.4 14.9 12.4 44.0 12.2 12.5 9.2 54.8 64.0 19.4 8.9 10.9 16.8 20.9 21.0 10.1 18.4 43.0 13.1 17.4 20.9 52.1 24.6 38.4 50.0 63.5 15.9 18.4 10.7 39.4 PKD2L1 "PCL, PKD2L, PKDL, TRPP3" ENSG00000107593 "Polycystin 2 like 1, transient receptor potential cation channel" Q9P0L9 10 100288149-100330264 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.8;lymphoid tissue: 7.9;retina: 13.3" "Cell type enhanced" "Detected in some" "Early spermatids: 14.6;Hofbauer cells: 13.6;Horizontal cells: 60.6;Kupffer cells: 14.4;Late spermatids: 20.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB022621, HPA070002" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Actin filaments, Cytosol" "CAB022621: , HPA070002: " "unprognostic (2.67e-1)" "unprognostic (3.66e-7)" "unprognostic (8.07e-3)" "unprognostic (4.38e-2)" "unprognostic (4.70e-2)" "unprognostic (5.31e-2)" "unprognostic (2.19e-1)" "unprognostic (2.85e-2)" "unprognostic (2.01e-1)" "unprognostic (9.25e-2)" "unprognostic (1.55e-1)" "unprognostic (9.37e-2)" "unprognostic (1.49e-4)" "unprognostic (3.00e-1)" "unprognostic (2.05e-2)" "unprognostic (7.94e-2)" "unprognostic (2.25e-1)" 0.2 0.1 5.4 0.4 5.6 0.9 0.7 4.8 10.8 0.1 4.8 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.4 4.9 0.3 1.6 2.3 1.5 4.9 5.2 0.1 0.1 0.0 0.1 0.5 5.1 0.3 1.2 13.3 0.1 0.0 0.1 0.0 0.6 0.0 5.0 7.9 0.0 2.3 5.0 0.9 0.0 0.0 1.7 0.2 0.0 5.5 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.1 5.4 5.6 4.8 10.8 5.4 4.9 4.9 5.2 5.1 5.0 5.0 5.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 14.6 0.0 0.0 0.1 0.0 0.0 2.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 13.6 60.6 0.4 0.0 0.0 14.4 0.0 20.1 0.3 3.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 PKP4 p0071 ENSG00000144283 "Plakophilin 4" Q99569 2 158456952-158682879 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 256.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 261.0;Inhibitory neurons: 260.9;Oligodendrocyte precursor cells: 235.3;Oligodendrocytes: 864.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037334, HPA066647, HPA070648" Approved Enhanced "Plasma membrane,Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 39: CACO-2 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Plasma membrane" "CAB037334: , HPA066647: AB_2685696, HPA070648: AB_2686291" "unprognostic (2.76e-1)" "unprognostic (5.26e-2)" "unprognostic (1.48e-2)" "prognostic favorable (5.80e-4)" "unprognostic (2.34e-2)" "unprognostic (1.63e-1)" "unprognostic (1.02e-3)" "unprognostic (2.43e-1)" "unprognostic (1.04e-2)" "unprognostic (9.53e-2)" "unprognostic (1.82e-2)" "unprognostic (9.69e-2)" "prognostic favorable (3.29e-7)" "unprognostic (2.23e-1)" "unprognostic (9.80e-2)" "unprognostic (1.33e-3)" "unprognostic (2.28e-3)" 13.4 6.5 165.2 6.7 229.0 8.3 26.2 186.6 212.7 31.9 89.3 12.6 12.4 14.0 14.2 17.8 19.6 15.3 22.1 130.2 179.5 57.0 16.8 12.6 6.0 256.9 217.1 13.3 15.1 18.1 9.6 6.2 213.7 12.9 13.4 18.5 34.0 20.9 8.2 16.1 11.3 14.3 222.9 6.1 13.8 10.3 194.1 16.1 30.4 9.8 10.1 16.5 12.4 239.5 36.9 21.8 26.7 30.4 12.1 13.4 25.7 29.1 15.9 44.5 38.4 72.4 32.5 23.4 21.5 35.4 16.0 29.0 35.2 29.8 74.1 35.4 19.2 21.2 23.5 56.3 20.9 34.4 4.6 5.7 28.1 30.0 46.3 26.7 23.0 28.9 30.1 33.3 34.7 42.6 15.2 14.3 28.8 51.4 15.9 20.6 40.2 19.3 64.6 26.6 46.2 8.2 20.3 30.4 24.5 24.9 34.7 31.3 10.6 25.9 29.2 19.3 38.2 19.8 18.0 17.0 14.8 19.2 25.4 0.0 0.3 0.0 0.1 0.1 0.2 0.0 0.5 0.2 0.1 0.0 0.4 0.1 0.4 0.0 2.0 0.2 0.7 0.2 165.2 229.0 186.6 212.7 130.2 179.5 256.9 217.1 213.7 222.9 194.1 239.5 59.8 41.7 18.9 28.7 3.1 27.0 21.3 23.5 34.1 44.5 44.3 35.9 49.7 38.6 28.7 47.8 29.2 0.2 3.5 17.7 23.5 21.3 14.6 21.0 12.2 71.1 9.0 24.6 261.0 18.1 0.3 15.3 26.0 38.5 10.1 11.8 23.2 28.6 3.1 5.0 260.9 16.6 16.2 7.6 10.0 9.2 10.8 6.2 7.2 163.9 4.5 8.6 2.1 235.3 864.7 17.4 16.7 17.0 5.2 44.6 12.4 33.1 29.0 19.2 13.1 11.4 13.9 15.4 6.3 30.4 30.4 0.3 5.0 15.5 19.4 26.8 PLAA "DOA1, FLJ11281, FLJ12699, PLA2P, PLAP" ENSG00000137055 "Phospholipase A2 activating protein" Q9Y263 9 26903372-26947242 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Neurogenesis "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005035, HPA020994, HPA020996" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 12000000 "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB005035: AB_562036, HPA020994: AB_1855444, HPA020996: AB_1855445" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (4.00e-3)" "unprognostic (5.00e-1)" "unprognostic (1.61e-1)" "unprognostic (4.06e-2)" "unprognostic (4.50e-3)" "unprognostic (2.48e-1)" "unprognostic (5.54e-2)" "prognostic favorable (7.87e-4)" "unprognostic (3.24e-2)" "unprognostic (1.44e-1)" "unprognostic (9.29e-3)" "unprognostic (1.86e-2)" "unprognostic (6.68e-2)" "unprognostic (1.39e-2)" "unprognostic (5.10e-1)" 16.0 16.9 8.5 16.2 9.0 42.0 12.6 9.3 11.2 11.3 9.6 15.2 13.6 17.5 13.4 18.8 9.8 13.0 18.8 9.5 9.7 15.4 21.5 12.8 15.0 8.1 8.3 11.0 12.0 16.9 8.0 16.0 9.0 12.9 15.9 14.1 10.9 12.5 50.3 12.1 12.6 19.3 8.3 13.3 12.7 20.4 8.1 18.0 15.9 29.1 18.1 14.7 11.2 10.2 64.6 37.0 46.1 46.3 30.4 38.2 34.6 58.4 33.1 43.9 42.2 13.1 29.8 56.9 48.0 45.0 30.6 25.1 45.8 46.0 47.7 75.7 19.1 35.2 57.9 25.5 30.9 28.8 46.3 34.4 27.0 53.2 38.8 33.0 44.3 41.7 22.1 56.6 47.6 26.6 56.3 28.1 66.8 33.2 31.6 39.4 28.7 34.4 33.5 37.6 29.2 49.9 31.3 36.5 19.1 44.8 25.5 22.5 54.3 0.2 53.8 28.5 48.3 18.4 43.7 59.5 30.8 40.4 23.4 21.9 12.7 21.0 11.0 18.2 12.6 14.3 11.5 11.4 13.1 11.9 10.3 12.0 11.4 14.9 21.2 6.6 18.0 9.6 8.5 9.0 9.3 11.2 9.5 9.7 8.1 8.3 9.0 8.3 8.1 10.2 10.8 16.0 11.2 18.3 18.8 11.0 11.3 14.6 17.1 9.1 7.5 6.6 23.8 5.7 16.1 9.2 0.0 24.9 14.9 11.9 9.8 17.6 27.7 10.2 12.3 17.1 9.6 25.9 31.9 16.2 26.6 11.5 15.8 14.7 40.6 13.2 12.5 10.7 20.7 5.0 30.8 8.6 14.2 15.8 8.2 6.6 8.7 17.5 1.8 21.5 15.9 9.5 16.5 24.6 32.1 15.2 8.7 8.2 23.1 10.6 11.0 12.3 12.7 6.7 19.7 13.0 34.1 28.1 24.9 20.9 9.5 49.3 18.3 21.5 12.6 11.6 PLAUR "CD87, UPAR, URKR" ENSG00000011422 "Plasminogen activator, urokinase receptor" Q03405 19 43646095-43670547 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "bone marrow: 688.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 820.7;Langerhans cells: 1833.9;Macrophages: 864.3;Urothelial cells: 2274.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1172.3" "Group enriched" "Detected in all" 4 "granulocytes: 1172.3;monocytes: 550.7" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 311.7;U-251 MG: 413.1;U-87 MG: 346.9;WM-115: 346.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050843, CAB073533" Uncertain Supported "Plasma membrane" "Intracellular and membrane" NA NA 4100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB073533: , HPA050843: AB_2681255" "unprognostic (9.28e-2)" "unprognostic (9.65e-3)" "unprognostic (1.39e-1)" "unprognostic (1.29e-3)" "unprognostic (3.59e-3)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "prognostic unfavorable (2.33e-5)" "unprognostic (8.08e-3)" "unprognostic (4.30e-2)" "unprognostic (2.29e-3)" "unprognostic (5.30e-2)" "prognostic unfavorable (7.83e-9)" "unprognostic (4.99e-2)" "unprognostic (1.66e-1)" "unprognostic (5.45e-2)" "unprognostic (9.33e-2)" 52.1 10.4 7.5 81.7 9.8 688.4 14.5 11.2 32.4 30.9 10.3 26.7 10.0 30.2 4.8 11.6 22.8 78.1 23.0 8.1 10.4 18.2 19.8 69.5 10.6 12.2 9.8 14.9 13.6 5.4 9.1 35.9 13.3 11.5 20.1 2.8 21.7 5.8 3.6 7.8 10.6 26.2 9.7 20.4 28.4 3.1 24.8 10.2 9.5 4.7 8.6 109.7 15.8 13.8 83.9 31.0 26.1 1.9 23.4 83.3 16.2 180.7 189.6 114.6 141.4 2.4 95.1 2.4 43.0 116.9 66.8 35.2 7.0 46.4 127.9 5.3 5.3 15.8 44.7 3.9 30.6 18.8 195.2 87.4 9.0 311.7 46.5 160.6 129.0 19.1 16.4 2.2 107.7 6.1 21.0 55.3 8.7 156.1 64.7 24.0 17.4 5.6 35.9 3.8 1.3 22.2 82.0 17.4 25.0 12.6 3.2 59.4 129.7 230.0 121.1 109.8 413.1 3.0 9.0 0.6 346.9 36.0 346.5 87.7 476.5 745.5 6.8 427.9 8.3 2.7 8.9 5.7 213.6 1.4 3.2 4.0 1172.3 6.7 550.7 69.3 3.6 253.9 7.5 9.8 11.2 32.4 8.1 10.4 12.2 9.8 13.3 9.7 24.8 13.8 23.1 73.7 76.6 2.3 15.5 105.2 820.7 274.2 72.3 0.7 45.8 22.5 4.5 24.3 151.9 20.2 0.0 6.5 17.4 314.5 1.9 219.3 0.9 188.1 68.0 64.9 14.8 5.2 2.5 106.5 58.8 145.4 156.0 519.1 305.2 4.2 19.2 1.7 428.9 10.1 3.3 85.3 22.4 155.4 1833.9 2.0 6.8 864.3 72.9 5.6 52.1 1.2 4.1 1.5 0.9 558.8 435.5 4.1 14.5 479.4 12.7 2.7 52.7 0.7 6.6 38.5 90.0 1.2 4.7 202.6 63.1 13.1 33.2 3.1 29.3 2274.4 PLEKHG3 "ARHGEF43, KIAA0599" ENSG00000126822 "Pleckstrin homology and RhoGEF domain containing G3" A1L390 14 64704102-64750249 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 179.2" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 90.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 24.0;NK-cells: 9.4;T-cells: 16.2" "Cell line enhanced" "Detected in many" "A-431: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063455, HPA065323, HPA073702, HPA074734" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Centrosome,Cytosol" Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Cytokinetic bridge, Centrosome" "HPA063455: AB_2685015, HPA065323: AB_2685467, HPA073702: AB_2732238, HPA074734: AB_2732265" "unprognostic (8.71e-2)" "unprognostic (1.69e-1)" "unprognostic (4.38e-2)" "unprognostic (4.04e-2)" "unprognostic (2.18e-1)" "unprognostic (7.22e-2)" "unprognostic (7.21e-2)" "unprognostic (5.53e-3)" "unprognostic (1.49e-1)" "unprognostic (3.34e-3)" "unprognostic (3.63e-1)" "unprognostic (3.54e-2)" "prognostic favorable (7.39e-8)" "unprognostic (2.29e-1)" "unprognostic (2.67e-1)" "unprognostic (4.24e-2)" "unprognostic (2.67e-3)" 25.2 3.5 44.0 10.7 92.5 16.3 23.4 47.2 74.1 33.9 53.0 39.0 13.0 67.5 5.0 45.8 38.1 22.6 17.2 44.5 46.7 36.0 36.3 14.3 5.6 65.8 66.3 33.8 33.0 17.0 6.8 29.3 60.9 24.2 15.5 2.9 29.2 37.5 9.7 44.9 13.2 26.4 37.9 26.6 22.3 5.7 74.1 4.6 23.7 7.4 4.9 32.2 39.1 179.2 78.4 36.5 29.8 45.3 3.1 0.0 49.0 8.7 10.4 13.8 11.0 38.9 34.3 0.0 15.3 8.6 4.8 74.6 20.3 69.7 4.7 0.2 16.7 35.1 48.3 9.2 4.0 1.3 16.1 3.9 39.6 2.9 24.4 22.9 9.1 0.3 0.0 0.4 4.6 37.5 0.1 32.0 10.0 21.2 37.0 0.4 14.7 5.5 37.0 58.0 9.9 18.0 17.7 26.7 25.1 27.5 29.0 8.0 16.6 6.0 59.8 0.3 12.3 0.1 0.2 0.1 0.6 3.7 10.7 9.0 3.0 18.2 16.2 1.5 11.1 0.0 5.0 7.3 1.0 0.0 0.5 3.6 24.0 9.4 1.0 0.0 1.7 5.3 44.0 92.5 47.2 74.1 44.5 46.7 65.8 66.3 60.9 37.9 74.1 179.2 3.1 3.2 6.2 15.0 0.7 19.4 19.4 15.1 21.6 5.5 16.0 9.8 7.8 12.8 6.0 47.8 0.0 7.9 14.5 24.7 11.7 26.7 0.9 18.6 18.5 4.0 34.7 0.4 1.0 20.6 9.5 7.4 14.3 23.6 1.3 1.9 3.6 10.1 5.5 0.0 3.2 26.9 18.3 6.5 8.0 1.5 7.5 2.7 5.4 6.5 4.6 9.1 45.3 10.6 90.9 35.3 16.7 25.6 2.8 16.1 2.3 9.5 4.0 0.8 26.3 5.1 25.3 0.2 1.6 25.6 21.5 2.6 9.0 10.5 13.2 32.2 PLPP1 "LPP1, PAP-2a, PPAP2A" ENSG00000067113 "Phospholipid phosphatase 1" O14494 5 55424854-55534969 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 359.1;Endometrial stromal cells: 206.7;Hepatic stellate cells: 267.0;Leydig cells: 219.3;Prostatic glandular cells: 182.0" "Cancer enhanced" "Detected in all" "prostate cancer: 200.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 445.7;fHDF/TERT166: 142.8;HMC-1: 235.8;HSkMC: 171.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033331, HPA047815" Enhanced Supported "Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB033331: AB_2168044, HPA047815: AB_2680164" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.36e-1)" "prognostic favorable (6.06e-4)" "unprognostic (2.81e-1)" "unprognostic (2.20e-1)" "unprognostic (4.05e-3)" "unprognostic (2.43e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (3.94e-2)" "unprognostic (1.66e-1)" "unprognostic (3.11e-2)" 172.3 78.1 51.5 42.3 59.9 0.9 140.7 63.7 59.4 88.7 59.6 118.3 47.4 119.5 39.8 42.4 73.4 167.5 117.1 49.9 56.8 104.0 67.7 56.2 32.2 62.1 56.2 29.4 35.6 49.0 27.8 37.6 64.2 254.1 65.8 9.7 32.9 61.3 70.0 57.9 79.1 108.9 62.5 31.1 70.9 21.0 58.6 15.8 112.9 81.5 24.2 128.8 63.8 72.9 9.8 24.4 7.0 14.2 445.7 51.8 9.6 21.8 61.4 11.9 27.9 16.7 17.7 10.2 20.0 142.8 31.9 6.5 25.2 12.6 13.5 6.8 20.1 1.1 9.6 21.3 70.5 2.5 235.8 171.3 25.7 17.6 10.9 23.3 19.9 9.1 0.2 27.0 24.1 6.0 6.8 5.5 15.5 1.1 20.0 2.0 11.7 0.9 46.3 79.8 8.4 5.8 21.5 4.2 13.4 28.8 15.6 1.6 24.0 4.0 6.9 17.8 15.5 16.6 7.4 11.8 15.7 1.3 19.5 0.0 0.4 4.0 1.6 0.5 1.7 6.7 5.3 3.4 2.0 3.3 9.5 7.7 0.3 3.0 0.9 15.0 2.6 1.8 51.5 59.9 63.7 59.4 49.9 56.8 62.1 56.2 64.2 62.5 58.6 72.9 359.1 6.4 9.4 0.0 9.8 0.0 51.0 0.0 10.2 4.0 8.4 45.7 0.0 21.5 5.6 29.5 2.1 3.3 5.4 61.0 5.9 25.2 44.4 10.7 206.7 112.3 1.2 5.7 0.0 28.5 11.1 115.5 11.2 18.5 27.8 4.0 267.0 48.3 12.8 1.7 0.0 20.2 0.0 12.0 0.0 21.0 219.3 8.1 0.0 0.0 4.5 16.6 1.0 0.0 0.0 30.0 24.6 88.4 13.0 182.0 49.4 29.3 2.2 5.6 59.2 89.7 49.7 54.4 17.7 10.0 0.0 4.9 11.3 3.1 12.1 42.8 PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291403 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 204.5;Ductal cells: 352.1;Proximal enterocytes: 209.8;Rod photoreceptor cells: 234.9;Urothelial cells: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.2;MAIT T-cell: 6.6" "Lineage enriched" "Detected in single" 41 "T-cells: 6.6" "Cell line enhanced" "Detected in many" "A549: 144.1;CAPAN-2: 154.6;OE19: 255.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055540, HPA058428" Uncertain Supported "Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA055540: AB_2682839, HPA058428: " "prognostic unfavorable (4.55e-4)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.21e-8)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.83e-3)" "unprognostic (5.48e-2)" "unprognostic (1.59e-1)" "unprognostic (5.67e-2)" "unprognostic (1.18e-3)" "unprognostic (3.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-3)" 4.8 13.2 37.7 8.5 61.6 0.0 36.9 57.1 50.0 63.4 26.2 40.5 62.7 16.8 8.4 27.2 81.8 52.4 1.7 38.8 43.5 11.5 3.7 8.3 1.4 57.3 53.6 2.7 37.3 19.5 11.8 3.6 56.2 31.7 32.1 29.6 105.7 32.9 0.6 53.2 51.0 6.4 44.8 4.7 50.3 7.6 49.2 5.2 5.7 0.5 6.0 36.5 14.2 83.9 85.5 144.1 2.1 0.1 0.0 0.3 0.2 8.2 0.0 25.3 18.9 41.7 154.6 0.0 88.3 11.9 0.1 45.3 0.0 17.6 11.1 0.8 2.6 0.0 55.9 0.0 28.6 0.0 5.5 5.2 7.6 12.7 16.7 53.4 4.2 0.0 0.7 0.1 0.0 98.5 0.4 0.1 61.5 255.8 0.0 0.0 0.0 2.4 62.1 13.7 17.4 40.9 23.3 38.3 60.3 5.8 50.0 2.5 4.5 55.7 36.5 0.5 61.9 0.8 101.7 70.4 15.5 0.0 46.9 0.0 0.0 0.0 3.2 0.0 6.6 0.0 1.3 1.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 37.7 61.6 57.1 50.0 38.8 43.5 57.3 53.6 56.2 44.8 49.2 83.9 17.0 6.4 7.5 0.0 1.5 0.0 134.2 0.0 8.0 19.7 137.1 149.9 0.0 204.5 35.3 22.0 10.4 0.5 2.7 77.0 3.9 352.1 0.3 115.2 9.2 15.2 8.5 0.0 0.0 139.5 15.1 3.0 91.3 90.1 1.3 0.0 0.0 0.5 0.9 16.8 0.0 38.8 0.0 1.0 0.0 1.6 0.0 1.9 0.0 0.0 2.6 21.7 0.0 0.0 0.0 128.8 85.2 0.0 1.6 97.4 209.8 1.4 91.1 234.9 0.0 0.8 2.7 0.6 35.1 20.3 0.0 0.8 3.5 0.1 87.2 205.8 PLSCR1 MMTRA1B ENSG00000188313 "Phospholipid scramblase 1" O15162 3 146515180-146544856 "Predicted intracellular proteins, Transporters" "Antiviral defense, Host-virus interaction" "DNA-binding, Host cell receptor for virus entry, Hydrolase, Nuclease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 291.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 319.8;BJ hTERT+ SV40 Large T+ RasG12V: 418.6;HHSteC: 292.9;SK-MEL-30: 569.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068923, CAB070421" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB070421: AB_11153452, HPA068923: AB_2686059" "unprognostic (7.88e-2)" "unprognostic (1.10e-1)" "unprognostic (5.34e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.12e-1)" "unprognostic (3.35e-1)" "unprognostic (5.22e-2)" "unprognostic (7.73e-3)" "unprognostic (9.19e-3)" "unprognostic (6.93e-3)" "unprognostic (3.07e-3)" "unprognostic (1.10e-1)" "unprognostic (1.09e-3)" "unprognostic (5.26e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-1)" "unprognostic (1.63e-1)" 60.6 23.0 11.4 86.7 12.5 64.4 45.9 12.7 17.6 25.9 11.9 65.0 39.8 28.2 31.0 47.9 40.0 66.1 24.3 12.1 13.5 71.9 49.2 49.3 40.6 17.4 14.2 34.9 38.3 16.8 15.4 56.3 15.3 23.7 59.5 9.8 49.1 49.6 10.8 13.6 45.4 41.9 16.2 64.5 44.0 17.1 14.7 30.0 27.8 17.6 39.4 68.1 29.5 14.0 106.2 41.5 26.4 12.1 40.9 65.0 40.5 32.6 88.4 319.8 418.6 34.0 88.1 8.4 75.6 20.6 245.9 86.2 21.2 32.7 56.6 32.9 21.6 66.1 12.5 25.2 292.9 40.3 35.4 106.3 53.3 36.6 182.3 52.6 49.4 19.1 44.7 104.0 66.9 41.0 30.6 16.1 25.8 71.6 37.6 27.4 28.1 2.9 95.9 29.6 16.3 0.0 42.6 20.9 569.9 35.8 20.7 46.8 30.6 26.9 22.7 59.1 55.8 79.2 15.6 0.4 27.0 29.0 23.3 41.1 157.6 44.3 20.8 159.6 30.0 25.2 13.5 18.5 105.8 19.7 9.3 13.9 100.0 57.8 94.8 28.5 8.3 79.3 11.4 12.5 12.7 17.6 12.1 13.5 17.4 14.2 15.3 16.2 14.7 14.0 191.4 35.3 43.0 12.7 28.2 37.0 106.5 92.1 26.2 0.7 36.0 22.6 7.3 124.4 110.4 95.6 0.0 53.7 25.4 134.2 74.3 291.6 2.0 56.1 24.5 135.2 33.1 18.3 7.1 217.4 114.1 74.8 47.9 58.2 28.4 60.5 100.6 29.7 139.9 0.0 9.0 71.5 79.3 86.2 162.9 6.8 114.9 185.5 48.0 35.6 72.3 64.3 32.0 7.1 0.3 157.6 110.3 45.9 18.2 79.6 40.7 75.0 133.5 1.6 39.5 63.4 59.2 1.5 2.4 21.8 28.6 44.5 25.9 42.6 69.4 211.9 PODXL "Gp200, PC, PCLP" ENSG00000128567 "Podocalyxin like" O00592 7 131500262-131558217 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 96.2" "Cell type enhanced" "Detected in many" "Adipocytes: 165.8;Cone photoreceptor cells: 87.6;Endothelial cells: 181.1;Glandular and luminal cells: 121.3;Microglial cells: 92.8;Rod photoreceptor cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 295.8;NTERA-2: 509.7;SuSa: 640.8;TIME: 474.0;U-251 MG: 226.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002110, CAB016169, HPA045507, CAB062558, CAB068219, CAB068220" Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA 33000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Centriolar satellite" Vesicles "CAB016169: AB_628165, CAB062558: AB_2665627, CAB068219: AB_2665618, CAB068220: AB_2665619, HPA002110: AB_1855512, HPA045507: AB_2679356" "unprognostic (1.26e-1)" "unprognostic (7.68e-2)" "unprognostic (8.28e-3)" "unprognostic (6.46e-3)" "unprognostic (5.16e-3)" "unprognostic (5.85e-2)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (7.95e-3)" "unprognostic (3.52e-1)" "unprognostic (9.20e-3)" "unprognostic (3.40e-1)" "prognostic favorable (2.89e-4)" "unprognostic (2.56e-1)" "unprognostic (8.78e-3)" "unprognostic (3.55e-2)" "unprognostic (1.03e-1)" 20.8 6.8 27.7 8.9 26.5 0.3 21.9 25.2 34.4 26.0 19.0 8.4 5.1 27.5 5.6 8.1 49.0 14.5 29.1 25.2 25.3 96.2 3.0 31.8 5.6 29.2 28.1 6.1 26.0 18.9 1.1 29.3 29.5 8.7 8.6 67.8 16.1 18.9 15.3 4.8 6.2 28.9 22.0 5.6 5.6 2.4 42.0 3.7 28.5 26.1 6.1 9.6 1.0 22.0 50.9 18.9 42.6 16.3 0.5 0.0 2.6 5.4 4.2 16.9 6.1 121.4 83.1 0.3 109.7 295.8 57.1 34.9 34.3 0.7 15.3 5.4 17.3 0.2 115.0 2.7 1.1 4.2 4.0 0.2 0.4 50.5 0.8 9.4 146.3 1.5 10.5 1.8 16.9 18.0 0.5 1.3 509.7 10.0 43.6 16.2 73.1 15.8 1.6 16.6 34.3 8.9 34.7 7.0 0.2 640.8 4.1 2.2 474.0 6.8 26.6 72.5 226.1 2.5 4.5 1.2 27.1 20.1 48.4 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 26.5 25.2 34.4 25.2 25.3 29.2 28.1 29.5 22.0 42.0 22.0 165.8 6.4 9.9 3.6 2.4 5.2 0.9 14.0 0.6 9.7 33.3 20.7 22.9 4.3 25.4 27.6 87.6 0.8 1.0 1.0 0.0 4.6 0.8 44.8 13.0 181.1 2.4 2.7 9.4 18.3 0.4 9.2 1.1 121.3 2.5 2.2 65.0 1.0 0.4 5.0 3.3 12.9 4.1 0.9 9.6 1.3 4.7 2.6 5.4 92.8 0.7 10.6 0.0 7.1 3.1 42.7 0.8 0.4 4.3 3.6 0.7 0.8 10.3 188.4 0.0 6.3 8.4 0.3 1.1 1.3 3.1 0.7 3.3 1.9 2.7 5.8 PPIP5K1 "HISPPD2A, IPS1, KIAA0377, VIP1" ENSG00000168781 "Diphosphoinositol pentakisphosphate kinase 1" Q6PFW1 15 43533462-43590253 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 41.7;Excitatory neurons: 46.6;Inhibitory neurons: 37.6;Rod photoreceptor cells: 44.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 45.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039380 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 21: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA039380: AB_10673528" "unprognostic (8.72e-2)" "unprognostic (6.49e-2)" "unprognostic (1.90e-2)" "unprognostic (1.12e-1)" "unprognostic (2.38e-1)" "unprognostic (2.78e-1)" "unprognostic (8.18e-2)" "unprognostic (5.78e-2)" "unprognostic (2.59e-3)" "prognostic unfavorable (8.57e-4)" "unprognostic (6.67e-2)" "unprognostic (2.85e-3)" "prognostic favorable (7.14e-8)" "unprognostic (2.67e-2)" "unprognostic (3.35e-2)" "unprognostic (5.92e-3)" "unprognostic (7.95e-3)" 6.6 14.8 5.7 7.3 9.8 5.9 10.3 45.4 21.0 8.3 1.1 17.6 24.7 7.4 15.1 11.6 9.4 8.3 7.5 8.0 1.8 8.5 5.6 5.8 7.8 6.0 0.6 9.2 9.4 33.7 21.6 4.5 8.8 10.0 17.6 53.7 13.8 8.3 20.0 20.0 24.3 7.7 0.0 8.6 15.5 15.5 2.8 5.4 14.3 21.2 10.0 9.0 9.9 9.2 14.5 9.3 8.1 15.0 4.8 3.0 13.8 7.1 9.0 10.0 14.6 11.0 13.5 13.5 10.5 9.8 14.9 38.6 15.8 30.6 10.1 13.3 12.5 20.3 29.9 5.9 11.0 23.4 20.2 5.4 26.6 12.2 18.6 13.5 10.7 31.0 15.0 19.4 7.4 11.3 7.8 13.2 3.9 27.0 10.0 16.7 8.2 6.8 10.7 25.9 24.1 7.6 18.3 17.2 6.7 11.4 31.7 19.4 4.7 8.7 10.2 11.1 17.4 4.3 5.7 16.4 16.3 26.5 8.5 2.4 0.5 0.0 1.0 1.1 1.3 2.0 1.2 1.3 1.2 1.2 0.9 0.9 0.3 1.5 0.8 0.9 0.3 1.3 5.7 9.8 45.4 21.0 8.0 1.8 6.0 0.6 8.8 0.0 2.8 9.2 2.3 0.0 2.2 11.4 5.2 4.0 1.5 3.2 7.4 16.5 3.2 3.3 5.4 2.8 3.4 7.3 41.7 3.3 2.9 9.2 0.0 2.1 2.7 2.1 1.4 2.9 2.4 5.5 46.6 1.5 0.9 1.8 20.9 2.8 0.0 9.5 3.3 1.8 1.9 10.1 37.6 5.9 0.0 2.8 1.8 2.4 1.8 2.1 0.0 15.0 1.8 3.9 0.0 11.6 11.0 1.9 5.2 7.2 3.1 1.2 12.2 1.5 2.3 44.2 6.6 2.3 3.2 8.1 3.3 7.3 3.3 2.2 3.1 3.5 8.2 3.2 PPL ENSG00000118898 Periplakin O60437 16 4882507-4960741 "Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 728.1;vagina: 288.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Squamous epithelial cells: 138.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 86.5;HaCaT: 191.1;MCF7: 71.5;SiHa: 102.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA042550, HPA059859" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 80000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA042550: AB_2678048, HPA059859: AB_2684145" "unprognostic (2.12e-2)" "unprognostic (1.78e-1)" "unprognostic (1.16e-1)" "unprognostic (3.90e-2)" "unprognostic (2.84e-2)" "unprognostic (1.40e-1)" "unprognostic (3.70e-3)" "unprognostic (5.58e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (2.76e-4)" "unprognostic (2.41e-2)" "unprognostic (1.31e-1)" "unprognostic (4.13e-3)" "unprognostic (2.43e-2)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (7.86e-2)" 56.3 4.9 2.5 1.0 3.2 0.2 39.8 0.3 4.2 163.0 3.3 10.4 6.5 5.7 7.3 728.1 11.5 7.1 5.7 3.6 0.0 13.2 13.3 18.6 0.4 0.0 2.8 5.9 10.6 4.1 14.3 6.4 1.1 17.3 3.4 2.4 149.5 11.5 12.0 188.4 12.3 1.7 0.0 0.3 11.1 1.9 0.0 3.5 22.1 5.3 57.0 22.0 288.6 0.5 24.0 8.6 0.1 0.1 60.0 86.5 29.6 0.1 1.6 0.2 0.6 39.5 59.5 0.4 13.5 1.2 3.4 191.1 1.3 23.0 0.0 0.0 1.3 0.1 46.3 7.1 3.8 0.1 0.1 4.2 20.7 0.2 7.1 4.6 0.1 0.2 0.2 0.2 0.1 71.5 0.1 0.2 6.0 31.3 18.1 0.1 0.1 30.0 44.6 37.5 30.9 0.3 102.5 33.8 0.3 8.9 17.4 0.5 0.3 0.2 0.3 0.3 0.1 0.4 1.1 0.1 12.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 3.2 0.3 4.2 3.6 0.0 0.0 2.8 1.1 0.0 0.0 0.5 4.1 73.7 29.1 1.6 1.2 35.1 32.5 30.5 35.9 8.4 18.8 13.8 5.1 35.8 42.6 57.0 6.2 2.1 2.0 3.6 1.9 18.4 0.7 31.6 4.1 8.0 39.4 0.0 6.6 4.5 1.6 38.0 9.2 28.0 0.0 0.8 2.9 12.7 0.7 1.7 2.5 3.8 18.3 0.9 9.0 1.3 55.3 1.4 17.8 1.0 1.2 3.7 2.1 1.0 1.7 23.4 8.3 4.1 0.2 35.1 13.5 1.2 32.5 12.5 0.0 28.7 4.3 3.9 3.1 138.0 51.3 1.4 2.7 0.4 4.8 53.2 PPP1R16B "ANKRD4, KIAA0823, TIMAP" ENSG00000101445 "Protein phosphatase 1 regulatory subunit 16B" Q96T49 20 38805697-38923024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.6;lymphoid tissue: 41.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 119.4;Inhibitory neurons: 46.8;Oligodendrocyte precursor cells: 49.8;Oligodendrocytes: 238.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 57.3;HMC-1: 59.2;HUVEC TERT2: 35.6;U-266/70: 96.7;U-266/84: 41.8;U-698: 38.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049571, HPA079512" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "Nuclear speckles" "HPA049571: , HPA079512: " "unprognostic (2.62e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.67e-3)" "unprognostic (3.35e-3)" "unprognostic (2.19e-1)" "prognostic favorable (7.87e-5)" "unprognostic (1.13e-1)" "unprognostic (4.17e-2)" "unprognostic (4.31e-2)" "unprognostic (6.28e-2)" "unprognostic (4.09e-3)" "unprognostic (4.77e-2)" "unprognostic (3.45e-2)" "unprognostic (8.53e-2)" "unprognostic (3.75e-2)" "unprognostic (1.73e-1)" "unprognostic (7.90e-2)" 13.2 2.9 36.5 19.3 71.6 17.7 8.2 26.1 61.1 3.2 5.1 4.6 3.6 3.4 1.5 3.1 5.8 5.3 5.2 49.3 22.3 27.7 2.4 7.9 37.7 27.8 34.7 1.1 1.5 0.8 2.2 3.7 27.1 1.6 5.1 3.7 2.0 1.9 3.6 1.5 18.0 7.2 24.3 18.1 5.6 0.7 35.7 18.2 3.4 5.7 41.9 6.0 1.6 52.1 0.1 0.7 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 57.3 0.8 0.0 0.9 0.1 1.0 0.1 0.0 1.4 0.2 4.4 0.0 0.0 0.0 0.2 59.2 0.0 0.1 0.0 0.0 0.0 35.6 7.6 1.0 11.9 0.0 0.0 7.4 9.7 7.9 0.1 0.0 5.0 0.0 0.0 0.0 0.0 17.7 19.7 0.0 0.0 0.0 0.7 0.0 3.1 5.5 0.0 0.9 0.0 0.0 96.7 41.8 38.3 0.0 0.0 0.1 0.0 0.2 2.5 3.4 0.5 1.8 5.3 2.3 3.3 0.7 3.3 1.3 1.8 0.0 2.9 0.9 3.3 2.6 1.1 36.5 71.6 26.1 61.1 49.3 22.3 27.8 34.7 27.1 24.3 35.7 52.1 29.3 3.2 3.0 1.3 33.6 1.0 0.0 0.8 0.6 2.3 0.5 0.5 23.5 1.5 4.0 0.0 0.0 0.0 34.0 0.3 0.0 0.0 1.9 0.2 0.2 18.7 0.0 2.7 119.4 0.0 0.0 1.6 4.1 0.3 3.8 0.0 38.6 0.3 0.1 37.0 46.8 0.1 0.0 3.1 3.6 1.5 0.0 3.8 8.8 23.4 20.5 0.3 11.3 49.8 238.0 0.0 0.1 0.0 29.3 0.0 0.0 17.4 3.6 0.3 0.0 0.3 1.0 0.0 0.3 0.3 1.3 0.0 37.4 0.0 0.2 0.3 PPP3R1 "CALNB1, CNB, CNB1" ENSG00000221823 "Protein phosphatase 3 regulatory subunit B, alpha" P63098 2 68178857-68256237 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 189.9" "Cell type enhanced" "Detected in all" "Excitatory neurons: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005610, HPA047157" Approved Supported "Plasma membrane,Cytosol" NA NA 42000 "Cluster 46: Basophils - DNA binding" "Cluster 58: Brain - Synaptic function" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Cytosol "CAB005610: AB_325975, HPA047157: AB_2679960" "unprognostic (2.12e-1)" "unprognostic (2.09e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (9.08e-6)" "unprognostic (5.90e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.59e-1)" "unprognostic (3.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.70e-5)" "unprognostic (5.24e-3)" "unprognostic (5.35e-1)" "unprognostic (8.70e-2)" "unprognostic (1.24e-1)" 53.7 37.7 56.1 32.4 92.9 73.6 27.1 38.0 127.3 27.3 0.0 27.6 25.7 31.0 26.1 30.0 23.3 28.0 20.6 99.0 24.2 21.4 58.2 27.7 40.2 23.5 18.4 24.9 20.7 17.0 18.3 36.6 24.9 26.3 27.8 189.9 24.9 30.1 88.8 33.6 23.9 35.3 14.4 34.2 24.8 20.6 30.0 42.6 23.8 31.0 40.5 32.9 28.6 64.5 61.5 51.7 69.7 48.4 47.4 54.3 70.5 86.3 75.9 98.8 86.8 75.9 55.4 85.7 28.7 61.4 69.5 41.8 74.4 64.8 120.0 59.4 52.9 284.0 38.3 71.1 93.1 111.9 92.2 55.1 57.6 76.9 78.0 55.9 67.2 72.2 67.8 96.8 73.2 53.8 96.1 99.4 81.9 52.0 44.4 69.1 90.6 139.9 61.7 66.1 91.4 64.2 50.4 72.3 65.9 45.0 33.9 51.8 69.5 84.6 76.5 64.2 75.1 53.8 62.6 124.7 61.3 115.2 54.0 1.5 0.5 1.3 0.2 0.3 0.5 0.2 0.3 0.1 0.5 0.3 0.3 0.5 2.7 0.3 0.6 0.7 0.3 0.4 56.1 92.9 38.0 127.3 99.0 24.2 23.5 18.4 24.9 14.4 30.0 64.5 37.0 9.6 12.7 81.6 40.4 74.8 11.6 7.0 72.8 22.2 21.0 13.1 17.9 10.0 7.7 16.5 52.1 11.7 34.0 20.5 11.7 7.1 20.0 19.9 23.0 34.0 15.1 52.8 151.2 8.7 17.2 24.2 18.8 29.1 19.7 11.2 15.4 19.2 24.7 11.8 93.1 15.6 4.1 40.0 105.1 7.7 9.9 54.7 35.6 105.9 21.2 27.8 18.6 72.9 77.5 12.9 10.6 8.6 39.2 17.3 12.6 20.1 5.8 92.7 13.1 14.4 29.8 2.9 6.1 64.0 70.5 12.0 39.9 14.2 13.2 21.3 PRAME "CT130, MAPE" ENSG00000185686 "PRAME nuclear receptor transcriptional regulator" P78395 22 22547701-22559361 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Growth regulation, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 105.1" "Cell type enriched" "Detected in some" 4 "Spermatogonia: 249.0" "Cancer enhanced" "Detected in many" "melanoma: 139.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "K-562: 834.1" "Not detected" "Not detected" "HPA045153, HPA068562" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA045153: AB_10797259, HPA068562: " "unprognostic (9.36e-3)" "unprognostic (9.74e-2)" "unprognostic (1.02e-1)" "unprognostic (3.87e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (3.41e-4)" "unprognostic (3.43e-2)" "unprognostic (4.00e-2)" "unprognostic (1.33e-1)" "unprognostic (6.52e-3)" "unprognostic (9.68e-3)" "unprognostic (2.06e-1)" "prognostic unfavorable (7.48e-9)" "unprognostic (1.95e-1)" "unprognostic (2.21e-1)" "unprognostic (8.87e-2)" "unprognostic (1.26e-1)" 0.2 3.7 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.2 0.0 3.4 10.0 0.0 0.5 0.0 0.3 0.0 0.1 1.8 0.1 0.2 0.1 0.1 0.0 4.7 0.1 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.2 0.2 0.3 0.2 0.0 0.1 0.1 105.1 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.2 0.9 53.3 0.0 126.0 0.0 0.0 33.4 0.0 0.0 0.0 0.0 0.4 0.7 3.5 88.8 0.0 0.5 0.1 4.3 0.0 0.0 61.5 14.8 36.0 21.7 0.6 0.0 2.9 172.6 0.0 0.0 0.0 0.0 0.0 0.0 14.9 834.1 15.6 0.0 8.1 0.3 0.2 0.0 27.2 3.5 5.0 0.0 0.2 0.0 0.2 1.1 185.0 0.0 0.6 0.2 0.0 27.8 24.3 5.0 0.1 159.6 0.0 0.2 3.0 14.6 1.3 0.2 0.8 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 37.8 22.3 1.1 0.3 0.0 0.0 0.0 0.0 0.9 2.0 0.0 13.0 0.0 60.9 0.0 0.0 0.1 10.1 0.0 0.0 0.0 0.0 0.0 41.4 5.6 0.4 0.0 0.0 3.1 0.2 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.0 0.0 1.8 0.0 0.4 6.6 0.0 2.7 41.8 249.0 0.0 0.0 0.0 0.1 14.2 0.1 0.0 PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.5" "Cell type enhanced" "Detected in many" "Early spermatids: 206.5;Excitatory neurons: 394.4;Inhibitory neurons: 531.9;Late spermatids: 456.4;Oligodendrocyte precursor cells: 147.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.5;basal ganglia: 20.0;cerebral cortex: 34.5;hippocampal formation: 33.1;white matter: 17.1" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "REH: 27.0;TIME: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA008236, HPA044496" Enhanced Supported Supported "Vesicles,Plasma membrane,Intermediate filaments,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Intermediate filaments, Cytosol" "Vesicles, Plasma membrane" "CAB001948: , HPA008236: , HPA044496: AB_2678959" "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favorable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favorable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" 4.4 5.6 18.5 3.7 20.0 8.0 4.2 5.5 34.5 4.6 0.0 5.7 2.6 4.4 2.3 4.1 5.7 3.0 6.2 33.1 0.0 10.0 12.5 20.1 5.7 6.0 0.2 2.8 3.3 9.4 5.2 8.3 4.4 2.9 3.3 15.4 2.7 3.0 7.6 2.7 3.5 4.1 0.0 3.9 4.1 7.6 1.1 3.1 4.9 5.3 4.2 4.9 3.4 17.1 7.7 2.7 3.8 3.8 5.8 6.7 3.1 4.9 9.5 4.3 4.5 0.7 7.0 11.3 4.8 5.5 6.1 1.8 2.5 2.8 6.1 6.9 4.4 0.1 1.8 1.5 6.5 0.9 3.8 5.8 3.0 6.5 4.7 3.6 16.0 2.4 1.6 2.6 5.0 3.8 3.8 0.5 1.3 4.2 1.4 27.0 18.3 12.4 3.9 5.1 2.6 5.7 2.4 7.6 17.1 1.4 6.1 2.6 26.8 8.2 8.5 6.1 5.1 0.0 0.0 9.3 6.7 6.3 8.4 0.0 0.5 0.7 0.3 0.1 0.4 1.5 0.2 0.2 0.8 1.8 0.5 0.1 0.1 0.4 0.6 0.3 0.0 0.3 18.5 20.0 5.5 34.5 33.1 0.0 6.0 0.2 4.4 0.0 1.1 17.1 12.6 6.4 9.2 90.4 20.7 5.0 8.4 5.0 9.1 55.3 6.4 5.7 11.9 8.6 17.2 11.0 14.6 0.5 9.3 6.1 3.9 3.7 206.5 6.8 7.0 13.8 7.7 0.4 394.4 3.8 7.2 8.7 11.2 6.9 7.0 2.9 13.2 12.5 2.8 11.8 531.9 5.8 0.0 19.0 10.7 456.4 5.3 11.5 14.2 70.3 9.4 6.5 1.0 147.8 96.0 3.6 2.9 6.0 4.2 5.3 4.1 30.2 19.3 7.6 13.1 2.9 6.4 2.8 2.3 9.0 4.8 2.9 6.8 1.2 6.2 8.8 PRKD1 "PKC-mu, PKCM, PKD, PRKCM" ENSG00000184304 "Protein kinase D1" Q15139 14 29576479-30191898 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 362.1;Excitatory neurons: 147.4;Inhibitory neurons: 171.1;Microglial cells: 89.0;Oligodendrocyte precursor cells: 390.6" "Cancer enhanced" "Detected in all" "prostate cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 21.6;fHDF/TERT166: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018367, HPA029834" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Cytosol "CAB018367: AB_2253119, HPA029834: AB_10602821" "unprognostic (5.35e-2)" "unprognostic (3.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.70e-2)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-3)" "unprognostic (8.88e-2)" "unprognostic (2.37e-2)" "unprognostic (5.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.56e-1)" "prognostic favorable (2.44e-5)" "unprognostic (9.45e-4)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (3.89e-1)" 8.0 9.6 5.6 2.2 8.0 0.0 7.7 6.5 6.7 6.4 3.7 9.5 1.0 7.9 3.5 2.1 6.5 4.4 6.1 7.5 7.5 17.5 1.6 7.5 0.3 8.6 8.6 11.2 5.4 10.6 5.6 1.9 8.7 14.7 1.3 4.7 2.9 9.3 1.6 2.8 3.6 6.3 8.9 2.3 4.6 11.7 8.1 2.4 5.9 2.6 0.5 13.1 4.6 10.3 0.0 4.4 4.8 3.1 21.6 16.5 0.1 14.1 10.4 16.7 7.3 0.0 0.3 0.0 1.9 19.4 4.0 0.1 7.9 2.1 6.8 0.0 6.2 0.0 0.0 0.5 8.8 0.0 0.1 18.4 0.3 1.4 1.5 6.1 2.6 0.0 1.4 0.4 17.4 1.8 0.0 0.0 2.6 0.0 9.6 0.0 6.3 5.2 9.7 6.6 4.3 13.0 2.6 0.0 4.5 4.6 0.0 0.1 5.6 13.6 6.7 1.0 3.7 0.0 0.0 0.0 3.5 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.0 6.5 6.7 7.5 7.5 8.6 8.6 8.7 8.9 8.1 10.3 4.6 0.0 7.4 362.1 0.2 0.5 4.8 0.4 0.6 1.4 1.4 1.5 1.2 10.0 0.0 12.9 6.2 0.0 0.0 0.1 29.4 2.4 39.5 2.8 9.2 6.1 3.0 2.7 147.4 4.2 0.1 6.4 0.5 8.4 0.0 18.7 10.8 2.5 0.2 1.7 171.1 0.2 0.0 1.6 0.9 16.9 7.5 0.7 7.2 89.0 0.0 16.7 0.0 390.6 76.6 2.0 0.1 12.8 0.4 12.4 0.2 4.5 0.1 2.9 0.0 13.3 4.5 3.2 7.8 0.0 0.9 0.3 0.6 29.6 0.1 1.3 PRR7 MGC10772 ENSG00000131188 "Proline rich 7, synaptic" Q8TB68 5 177446445-177456286 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.7" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 66.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 24.7;SK-MEL-30: 26.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046636 Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA046636: AB_2679730" "unprognostic (3.69e-1)" "unprognostic (9.07e-2)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (4.08e-2)" "unprognostic (7.94e-3)" "prognostic unfavorable (1.50e-4)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (4.75e-2)" "unprognostic (5.86e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (1.98e-4)" "unprognostic (8.84e-3)" "unprognostic (2.22e-1)" "unprognostic (3.76e-2)" "unprognostic (1.69e-1)" 1.3 4.0 10.7 0.8 11.9 5.8 1.6 1.2 18.7 1.8 6.3 1.3 0.7 2.5 0.0 3.7 4.8 0.1 1.8 17.9 6.7 2.3 2.3 2.0 1.0 2.7 2.1 0.7 2.9 0.4 10.4 0.1 0.7 1.8 0.1 0.3 2.7 0.2 1.2 6.0 1.8 0.1 1.9 3.1 1.3 4.4 7.4 0.5 1.2 0.0 0.5 1.0 2.0 2.8 10.7 4.1 1.1 8.1 0.0 0.6 3.5 4.9 0.9 1.3 1.8 0.9 5.6 10.2 12.6 0.7 4.1 8.8 0.7 4.5 0.5 9.0 12.8 3.1 4.3 3.1 0.9 6.2 7.2 0.9 1.8 0.6 0.3 1.2 0.6 3.9 1.6 7.1 1.3 14.3 5.2 15.8 1.9 1.6 24.7 14.5 3.6 10.5 1.7 0.8 19.8 14.1 1.9 4.8 26.2 0.0 4.3 1.0 3.8 8.0 13.5 7.1 12.0 3.9 2.3 5.1 7.7 9.8 5.9 1.9 0.1 9.7 2.3 0.4 5.5 1.5 2.5 3.9 0.1 2.8 2.4 3.1 3.7 1.7 0.5 2.4 2.0 1.2 10.7 11.9 1.2 18.7 17.9 6.7 2.7 2.1 0.7 1.9 7.4 2.8 11.8 3.2 0.0 4.9 27.9 43.3 28.0 6.8 46.7 13.6 17.2 20.3 1.6 17.2 3.7 7.3 0.0 0.8 55.9 7.4 9.8 10.6 10.6 50.2 12.3 9.2 43.0 3.4 8.6 10.8 0.9 4.8 14.3 22.3 26.7 1.0 4.6 3.1 1.5 6.7 7.0 12.3 16.2 1.9 36.5 13.8 0.9 16.7 28.4 1.0 2.3 19.7 22.6 4.0 5.7 8.6 9.8 2.2 27.3 26.7 11.6 14.2 7.0 16.6 0.0 7.8 8.1 3.3 10.7 33.2 66.9 1.4 37.0 1.5 12.3 17.3 PRRT2 "DKFZp547J199, DSPB3, DYT10, EKD1, FICCA, FLJ25513, ICCA, IFITMD1, PKC" ENSG00000167371 "Proline rich transmembrane protein 2" Q7Z6L0 16 29811382-29815892 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Dystonia, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 124.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.3;Cone photoreceptor cells: 31.3;Leydig cells: 36.1;Peritubular cells: 40.3;Rod photoreceptor cells: 37.1" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 7 "NK-cells: 3.2" "Cell line enhanced" "Detected in many" "AF22: 24.1;HeLa: 13.8;hTERT-RPE1: 14.0;REH: 17.6;U-138 MG: 14.5" "HPA014447, HPA019203, HPA048045" Enhanced Supported "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA014447: AB_1855786, HPA019203: AB_2670097, HPA048045: " "unprognostic (7.60e-3)" "unprognostic (3.00e-1)" "unprognostic (8.32e-3)" "unprognostic (4.34e-2)" "unprognostic (3.72e-2)" "unprognostic (1.19e-3)" "unprognostic (2.85e-1)" "unprognostic (1.23e-1)" "unprognostic (9.30e-2)" "unprognostic (1.93e-1)" "unprognostic (4.45e-2)" "unprognostic (3.26e-2)" "unprognostic (3.43e-8)" "unprognostic (1.22e-1)" "unprognostic (1.17e-1)" "unprognostic (5.12e-2)" "unprognostic (2.44e-2)" 13.4 10.5 32.9 2.4 40.4 0.3 10.8 70.7 70.5 79.4 0.0 33.9 5.3 39.5 8.6 6.7 47.0 10.9 15.6 46.0 20.1 8.7 2.4 12.9 3.3 15.6 8.0 124.3 4.7 4.3 85.6 7.0 16.2 39.1 2.3 19.8 5.4 13.9 4.5 5.0 14.5 10.4 24.5 1.7 12.4 14.6 29.2 0.5 10.6 1.8 1.0 34.1 51.0 34.0 0.1 1.5 24.1 8.6 1.2 4.2 0.5 2.5 4.1 1.0 0.8 1.1 1.5 0.2 0.3 4.4 0.5 1.6 3.4 0.2 0.4 4.1 1.4 1.7 13.8 1.6 0.3 0.0 0.3 4.1 0.1 1.9 0.1 14.0 1.0 0.7 0.2 1.5 0.2 3.1 0.6 0.5 5.0 0.1 1.1 17.6 0.9 0.4 0.2 0.8 4.1 4.3 0.2 2.1 0.5 3.5 7.6 0.0 1.3 14.5 5.2 0.7 1.4 3.7 0.5 0.2 5.3 0.2 0.5 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 3.2 0.1 0.0 0.0 0.1 32.9 40.4 70.7 70.5 46.0 20.1 15.6 8.0 16.2 24.5 29.2 34.0 2.3 3.2 0.0 22.9 0.9 1.1 1.4 1.7 0.6 82.3 1.6 1.7 0.8 1.5 1.2 0.0 31.3 1.9 1.9 9.5 1.9 1.1 2.0 4.4 10.4 5.0 6.1 0.0 24.4 1.5 0.8 11.4 2.0 1.6 0.0 1.7 3.3 0.1 0.4 20.2 19.5 4.2 2.0 0.0 2.4 9.8 36.1 0.5 0.0 5.6 0.6 5.7 1.0 8.5 1.6 3.0 9.0 40.3 0.7 1.8 15.2 1.0 5.6 37.1 6.6 2.9 11.7 2.4 3.1 0.4 0.4 2.6 2.7 0.6 2.5 1.3 PSCA ENSG00000167653 "Prostate stem cell antigen" O43653 8 142670308-142682725 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 3019.3" "Cell type enriched" "Detected in many" 4 "Gastric mucus-secreting cells: 5332.3" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 785.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 22.4;HeLa: 45.7;OE19: 17.6;RT4: 61.7" "Not detected" "Not detected" "Region enriched" "Detected in many" 8 "spinal cord: 38.2" "HPA030783, HPA056418" Approved Supported "Plasma membrane" NA NA 18000 "Cluster 4: Stomach - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA030783: AB_2673611, HPA056418: AB_2683123" "unprognostic (1.21e-3)" "unprognostic (1.76e-3)" "unprognostic (3.20e-1)" "unprognostic (2.24e-1)" "unprognostic (1.77e-2)" "unprognostic (7.57e-2)" "unprognostic (1.93e-2)" "unprognostic (7.81e-3)" "unprognostic (8.25e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (6.82e-2)" "unprognostic (2.38e-3)" "unprognostic (4.93e-2)" "unprognostic (2.68e-1)" "unprognostic (3.07e-1)" "unprognostic (1.06e-3)" 4.8 0.4 0.5 0.5 0.6 0.2 1.9 0.3 0.9 67.8 0.2 7.8 4.0 0.4 0.6 334.0 7.9 10.0 0.4 0.6 0.2 5.8 0.7 6.3 0.1 0.5 0.3 0.6 3.2 0.0 0.6 2.4 0.4 230.6 4.8 0.0 23.5 1.9 0.3 11.1 2.5 0.1 0.2 0.4 3019.3 1.4 0.5 0.4 0.4 0.0 15.0 629.0 167.7 0.5 10.7 0.7 0.0 0.0 2.1 6.8 10.6 4.9 1.1 2.1 1.8 0.1 22.4 0.0 0.4 0.4 8.1 2.1 0.0 0.4 1.3 0.6 0.0 0.0 45.7 0.0 0.1 0.0 1.5 6.0 7.8 4.6 0.0 0.6 0.0 0.0 0.0 0.0 1.7 5.8 1.7 0.6 1.2 17.6 1.2 0.7 0.0 0.9 1.0 61.7 0.2 0.5 5.1 15.6 3.5 0.3 0.2 0.2 1.0 1.5 1.7 2.7 0.0 1.9 0.1 0.0 2.9 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.3 0.9 0.6 0.2 0.5 0.3 0.4 0.2 0.5 0.5 0.2 3.2 1.5 1.6 7.7 0.9 26.0 120.0 0.0 0.0 3.9 2.7 1.2 71.4 894.2 1.8 0.0 2.3 0.0 1.9 7.9 3.2 0.3 1.3 0.1 1.1 275.1 0.0 0.3 1.2 5.0 3.3 5332.3 0.3 0.0 0.3 0.0 0.0 0.6 0.0 0.2 12.9 179.0 0.6 1.0 0.4 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 57.1 0.2 0.0 13.4 238.7 0.3 0.4 994.9 0.0 0.0 0.0 48.9 0.0 0.5 13.1 1.3 28.5 4.6 0.0 0.9 1241.5 PSMC5 "p45, p45/SUG, S8, SUG-1, SUG1, TBP10, TRIP1" ENSG00000087191 "Proteasome 26S subunit, ATPase 5" P62195 17 63827152-63832026 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 596.6;Late spermatids: 1350.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017871, HPA064293" Enhanced Supported "Plasma membrane,Cytosol" NA NA 120000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA017871: AB_1857638, HPA064293: AB_2685234" "unprognostic (9.65e-2)" "unprognostic (1.63e-2)" "unprognostic (4.44e-1)" "unprognostic (2.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.35e-1)" "unprognostic (8.29e-3)" "unprognostic (1.24e-2)" "unprognostic (3.38e-1)" "unprognostic (2.85e-1)" "unprognostic (2.17e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (3.13e-6)" "unprognostic (9.54e-2)" "unprognostic (8.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.32e-1)" 90.4 99.0 134.8 80.9 137.5 82.4 80.6 141.3 159.0 79.6 130.2 106.1 68.0 80.1 112.3 104.9 83.2 59.4 107.5 136.2 139.3 120.9 112.7 68.1 93.0 140.5 140.2 63.3 71.0 161.1 82.5 75.5 141.2 81.4 84.4 85.3 73.4 86.7 236.2 121.5 70.6 90.3 137.7 82.4 84.5 73.3 139.6 93.3 86.4 168.7 108.0 93.4 79.6 138.9 240.1 369.1 233.9 172.9 171.4 174.7 202.8 225.3 197.0 327.1 243.8 390.3 154.7 158.7 154.7 241.6 246.0 182.8 239.1 228.5 383.5 136.8 289.7 330.3 288.9 362.4 180.1 336.0 230.4 177.5 171.4 291.9 266.6 139.1 263.7 180.9 258.4 210.2 284.9 450.7 279.4 237.4 215.6 266.3 330.0 248.9 445.5 244.3 249.0 270.9 203.2 274.1 158.6 313.9 152.3 254.4 306.8 197.8 238.8 360.3 329.9 161.5 482.6 220.5 335.2 250.4 225.8 255.7 241.5 105.1 120.4 149.4 164.1 176.3 222.8 142.7 191.6 179.3 140.0 122.0 161.3 183.1 37.7 167.4 206.3 108.6 272.1 216.1 134.8 137.5 141.3 159.0 136.2 139.3 140.5 140.2 141.2 137.7 139.6 138.9 97.9 51.3 78.6 8.5 82.7 94.6 145.0 206.3 71.7 84.9 71.1 79.1 156.0 110.1 139.6 68.0 18.8 250.4 85.1 98.8 246.5 195.2 596.6 75.4 69.4 104.7 90.9 107.7 7.9 214.5 187.2 101.4 69.3 68.1 90.2 53.3 86.4 130.9 162.9 72.3 7.9 92.7 197.4 89.8 85.0 1350.2 133.0 93.4 99.6 5.6 148.0 221.4 109.2 7.5 10.5 167.5 96.3 153.4 88.0 125.6 163.7 330.3 95.1 108.4 111.7 113.0 228.7 151.6 150.2 95.0 102.9 369.0 102.9 124.7 97.9 137.9 PSTPIP1 "CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP" ENSG00000140368 "Proline-serine-threonine phosphatase interacting protein 1" O43586 15 76993359-77037475 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Endocytosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 56.6;lymphoid tissue: 33.9" "Cell type enhanced" "Detected in many" "dendritic cells: 60.0;Enteroendocrine cells: 60.0;Hofbauer cells: 42.5;Kupffer cells: 41.8;Macrophages: 41.8;monocytes: 51.1;NK-cells: 91.6;T-cells: 68.4;Theca cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 55.1;HL-60: 14.4;NB-4: 20.9;THP-1: 14.7;U-937: 59.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA010116, HPA010600, HPA072744" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA010116: , HPA010600: AB_1855870, HPA072744: " "unprognostic (4.42e-3)" "unprognostic (1.31e-3)" "unprognostic (3.56e-2)" "prognostic favorable (4.74e-5)" "unprognostic (3.79e-2)" "unprognostic (1.12e-3)" "unprognostic (2.16e-2)" "unprognostic (1.23e-2)" "unprognostic (1.16e-1)" "unprognostic (9.85e-2)" "unprognostic (2.96e-2)" "unprognostic (3.18e-1)" "prognostic unfavorable (7.36e-9)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.91e-1)" "unprognostic (5.42e-2)" 6.0 2.6 2.8 11.7 2.7 56.6 2.3 2.7 3.1 2.0 3.4 3.3 2.5 1.6 0.1 2.0 3.1 2.9 2.4 2.7 2.8 3.4 3.4 10.4 13.5 3.1 3.1 1.0 1.3 0.2 1.6 1.8 3.0 2.9 0.8 0.1 2.4 1.0 1.5 1.8 9.4 1.4 3.1 33.9 2.9 0.7 3.6 4.2 2.9 1.0 5.5 4.3 2.7 3.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 55.1 0.0 0.0 0.0 3.3 0.0 14.4 0.1 0.2 0.1 0.0 0.1 0.0 0.0 3.0 0.0 0.0 0.0 0.0 2.4 20.9 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.1 4.0 0.6 0.0 0.1 0.0 0.0 0.0 14.7 0.0 0.0 0.1 0.1 0.0 0.0 1.3 2.4 0.1 59.8 0.0 4.8 71.5 71.4 39.9 33.5 30.8 13.3 27.2 32.7 59.0 18.5 14.3 22.3 85.3 41.6 38.3 5.2 27.0 42.2 2.8 2.7 2.7 3.1 2.7 2.8 3.1 3.1 3.0 3.1 3.6 3.1 1.1 0.0 5.1 1.0 19.2 9.3 1.2 0.4 0.0 1.1 0.9 1.1 1.9 0.0 2.5 0.0 0.0 0.3 60.0 3.1 0.0 0.0 9.6 0.3 0.3 0.8 60.0 4.8 0.4 0.2 0.7 1.9 0.0 0.3 2.5 0.1 2.2 0.9 42.5 0.0 0.1 6.1 2.0 41.8 36.5 18.6 0.9 41.8 7.2 0.0 51.1 0.2 91.6 5.5 1.0 0.1 2.5 2.6 8.5 0.3 0.3 0.4 0.0 0.4 0.0 0.8 3.1 0.2 1.2 0.2 4.8 0.5 68.4 78.1 0.3 1.2 PTAFR ENSG00000169403 "Platelet activating factor receptor" P25105 1 28147166-28193936 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.1;lymphoid tissue: 30.8" "Cell type enhanced" "Detected in many" "granulocytes: 75.4;Hofbauer cells: 71.7;Kupffer cells: 93.0;Langerhans cells: 67.8;Macrophages: 64.5;monocytes: 52.8;Pancreatic endocrine cells: 89.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 256.7;eosinophil: 906.5;neutrophil: 747.1" "Group enriched" "Detected in many" 5 "granulocytes: 906.5;monocytes: 256.7" "Group enriched" "Detected in some" 4 "HBEC3-KT: 36.6;HMC-1: 131.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027543 Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA027543: AB_10610287" "unprognostic (2.22e-2)" "unprognostic (2.59e-2)" "unprognostic (6.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.75e-1)" "unprognostic (3.74e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.23e-1)" "unprognostic (2.39e-1)" "unprognostic (1.60e-1)" "unprognostic (2.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.59e-2)" "unprognostic (5.48e-2)" "unprognostic (1.38e-2)" 10.4 2.4 4.3 30.8 4.7 41.1 3.4 4.7 5.6 3.4 4.1 5.5 4.1 1.7 1.2 7.2 2.6 7.2 2.0 3.8 5.1 2.7 4.1 17.8 13.5 8.9 6.6 1.3 2.0 1.6 0.6 7.3 7.7 1.5 6.7 0.5 2.3 1.5 0.7 5.4 6.3 7.9 8.1 14.4 3.8 1.3 7.2 3.6 1.9 2.6 18.0 14.4 1.9 11.8 20.1 0.2 0.1 0.4 0.2 0.0 0.5 0.0 0.0 0.7 0.2 0.2 5.7 1.3 0.1 0.1 0.3 13.5 0.5 36.6 0.8 0.4 0.6 7.7 0.2 0.9 0.1 1.9 131.3 0.0 6.0 0.4 0.4 0.0 0.2 0.1 0.5 0.4 0.0 1.3 0.2 19.3 0.6 0.5 0.2 0.3 0.1 0.1 8.7 2.1 0.3 0.1 0.1 18.1 0.2 0.4 0.4 5.4 0.1 0.2 0.7 0.0 0.2 1.2 1.1 5.6 0.1 2.4 0.6 61.7 256.7 906.5 0.6 77.9 1.2 12.5 0.4 0.4 116.1 6.7 0.5 0.7 747.1 0.7 34.1 1.3 1.2 112.4 4.3 4.7 4.7 5.6 3.8 5.1 8.9 6.6 7.7 8.1 7.2 11.8 2.1 6.4 6.7 0.0 4.1 6.5 2.0 37.9 5.2 1.5 0.8 0.5 2.2 1.5 20.9 1.8 2.1 0.6 2.9 0.4 0.0 18.1 0.4 0.5 0.2 7.3 0.0 4.0 0.9 5.1 0.5 1.3 1.1 0.5 75.4 2.0 2.9 1.0 71.7 0.0 0.7 0.0 18.3 93.0 67.8 0.2 0.6 64.5 0.0 15.0 52.8 0.2 0.0 1.5 6.6 89.8 0.6 0.0 0.5 0.6 0.3 0.2 20.2 0.9 0.0 0.6 1.0 2.3 0.7 3.2 2.8 1.5 2.0 0.0 0.4 9.4 PTCH2 ENSG00000117425 "Patched 2" Q9Y6C5 1 44819844-44843253 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "ovary: 24.6;parathyroid gland: 59.1;salivary gland: 75.2;testis: 25.6" "Cell type enhanced" "Detected in many" "Leydig cells: 107.8;Peritubular cells: 68.1;Plasma cells: 67.1;Theca cells: 138.7" "Cancer enhanced" "Detected in many" "testis cancer: 9.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/84: 11.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046839 Supported "Nucleoli,Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Plasma membrane" Nucleoli "HPA046839: " "unprognostic (6.54e-5)" "unprognostic (1.05e-1)" "unprognostic (7.29e-3)" "unprognostic (3.65e-3)" "unprognostic (3.89e-1)" "unprognostic (7.42e-3)" "unprognostic (3.01e-1)" "unprognostic (2.94e-2)" "unprognostic (1.51e-1)" "unprognostic (8.67e-2)" "prognostic favorable (5.74e-5)" "unprognostic (2.92e-1)" "unprognostic (5.74e-6)" "unprognostic (1.55e-2)" "unprognostic (4.86e-2)" "unprognostic (6.31e-2)" "unprognostic (6.81e-2)" 4.2 3.1 6.1 0.8 3.5 9.4 3.4 6.8 6.8 5.1 3.6 3.6 1.0 6.4 1.6 0.9 4.3 2.5 1.3 3.1 4.4 1.3 1.3 1.0 2.3 2.9 4.8 24.6 1.0 59.1 9.9 0.3 2.0 3.0 0.9 3.6 75.2 1.3 2.0 3.6 1.8 1.2 1.6 2.4 2.0 25.6 6.5 0.8 4.6 0.8 0.7 3.1 3.4 4.8 0.2 0.3 1.0 2.5 0.8 0.9 1.0 0.8 1.6 0.5 0.4 0.2 0.4 1.1 0.4 0.4 0.5 0.0 1.1 0.0 0.2 2.1 1.9 0.6 1.0 0.8 0.3 0.7 1.1 0.3 0.4 1.0 0.1 1.7 0.1 1.0 0.7 1.1 0.0 0.5 1.4 2.1 0.3 0.1 0.4 1.0 0.2 0.5 0.2 0.0 1.5 0.6 0.3 0.4 0.8 0.5 0.2 1.2 0.1 0.2 0.5 1.3 0.5 1.9 11.6 3.2 0.6 3.0 0.4 2.5 1.9 0.1 0.5 0.9 1.0 1.0 0.6 0.6 1.2 1.4 0.7 0.6 0.6 0.9 0.9 3.6 0.3 0.2 6.1 3.5 6.8 6.8 3.1 4.4 2.9 4.8 2.0 1.6 6.5 4.8 2.8 0.0 1.1 14.0 13.4 0.5 0.7 1.0 0.6 0.8 4.8 8.0 1.0 7.2 1.0 1.8 2.1 2.4 6.8 7.8 0.0 5.5 2.3 9.3 13.5 2.7 11.5 1.3 23.7 1.8 1.6 14.3 28.1 8.5 0.0 4.4 0.7 7.9 6.7 8.4 27.3 4.9 2.0 24.5 2.2 8.0 107.8 17.3 0.0 5.6 3.9 2.4 2.1 9.5 2.6 2.1 2.5 68.1 67.1 0.8 13.6 0.2 1.7 1.2 13.1 5.4 5.6 5.0 3.6 0.6 1.6 2.3 7.5 138.7 5.5 0.2 PTK2B "CADTK, CAKB, FAK2, PTK, PYK2, RAFTK" ENSG00000120899 "Protein tyrosine kinase 2 beta" Q14289 8 27311482-27459391 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.3;brain: 102.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 109.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 127.4;REH: 141.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003850, HPA026091, HPA026276" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "CAB003850: AB_562205, HPA026091: AB_10599739, HPA026276: AB_10601234" "unprognostic (2.36e-2)" "prognostic favorable (3.32e-4)" "unprognostic (1.06e-1)" "unprognostic (7.36e-3)" "unprognostic (3.72e-2)" "unprognostic (3.11e-2)" "unprognostic (2.70e-2)" "unprognostic (2.13e-2)" "unprognostic (3.23e-1)" "unprognostic (1.45e-1)" "unprognostic (5.74e-2)" "unprognostic (3.32e-1)" "unprognostic (2.40e-3)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "prognostic favorable (5.11e-4)" "unprognostic (3.33e-3)" 19.7 10.8 46.9 52.6 54.4 106.3 11.5 22.8 102.9 11.5 38.3 29.8 34.1 9.9 8.9 19.2 15.6 12.7 10.6 96.3 8.5 15.9 15.2 28.6 78.3 0.0 26.0 4.7 12.6 7.1 13.7 8.0 0.0 25.5 23.5 4.4 26.6 12.3 5.0 45.2 48.8 10.7 0.2 78.3 22.2 9.5 27.0 86.0 12.5 5.4 73.6 21.0 15.1 37.0 38.2 10.4 2.8 3.0 76.6 5.5 21.5 2.9 1.9 1.9 2.7 9.9 21.5 127.4 4.0 5.8 3.1 34.3 1.1 31.3 1.1 8.7 0.8 26.4 10.6 2.0 15.7 28.5 45.5 41.6 46.0 2.6 17.3 13.0 1.0 36.0 31.7 85.6 2.1 4.0 49.1 57.0 2.2 33.0 2.6 141.2 0.7 88.3 8.5 29.5 19.2 3.5 13.4 9.3 5.0 6.5 11.5 72.1 17.5 1.3 2.8 2.5 1.0 68.0 32.0 68.9 5.2 60.6 2.4 47.3 48.4 36.9 33.9 43.0 22.2 46.0 17.0 24.3 36.1 46.6 20.8 25.9 45.8 29.0 53.5 11.7 18.2 50.1 46.9 54.4 22.8 102.9 96.3 8.5 0.0 26.0 0.0 0.2 27.0 37.0 6.9 3.2 29.8 16.6 64.3 37.7 38.7 19.7 6.8 5.4 5.9 7.7 3.7 8.6 13.0 14.7 0.0 2.9 33.4 65.5 0.0 8.0 1.2 7.1 1.8 9.6 7.8 20.2 109.2 8.3 26.5 3.5 22.4 5.3 28.5 1.1 5.0 24.1 23.1 8.4 9.2 21.9 10.2 68.4 32.1 1.0 1.5 55.3 8.8 22.5 62.5 2.8 70.0 7.5 15.1 13.3 42.0 0.7 68.1 18.6 44.6 16.1 13.9 3.9 0.0 3.3 3.3 4.2 6.4 4.8 30.1 1.9 46.6 1.0 18.1 17.9 PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase receptor type K" Q15262 6 127968785-128520616 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 889.9;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 1278.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.6;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 13000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "Vesicles, Plasma membrane" "HPA054056: AB_2682359, HPA054822: AB_2682614" "unprognostic (3.15e-2)" "unprognostic (1.07e-2)" "unprognostic (5.79e-3)" "unprognostic (4.95e-3)" "unprognostic (1.89e-2)" "unprognostic (7.26e-2)" "unprognostic (3.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.46e-1)" "prognostic favorable (9.33e-5)" "unprognostic (2.10e-1)" "unprognostic (1.55e-1)" "unprognostic (2.59e-1)" "unprognostic (9.32e-2)" 10.7 4.2 13.4 9.7 20.6 0.2 25.6 16.7 18.6 13.5 8.6 27.3 32.8 12.1 8.2 9.7 14.9 32.5 12.4 15.9 14.5 14.9 29.6 19.4 6.9 16.8 16.7 15.1 26.2 10.2 7.0 21.8 17.8 18.9 27.6 4.6 15.3 19.0 5.9 12.2 28.5 15.9 14.5 7.9 30.5 2.2 16.4 10.2 11.7 9.9 8.7 20.9 12.3 29.8 17.3 16.7 10.9 1.0 24.9 31.9 11.0 43.6 86.3 18.4 16.6 28.8 15.0 0.1 13.4 40.7 50.8 49.0 10.2 35.9 26.7 50.3 19.4 0.3 23.6 45.7 29.7 0.0 1.7 23.9 35.4 35.9 49.6 50.8 54.0 14.7 0.0 1.1 49.3 33.6 26.6 0.1 11.9 34.5 22.6 94.8 21.7 3.1 51.1 33.4 43.8 0.1 45.2 55.6 2.7 12.4 14.6 1.1 86.9 30.0 18.4 54.8 42.2 0.7 6.0 0.0 38.1 0.0 31.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.9 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.1 13.4 20.6 16.7 18.6 15.9 14.5 16.8 16.7 17.8 14.5 16.4 29.8 39.2 25.6 33.5 155.7 17.5 63.5 88.1 45.2 60.3 7.3 56.6 26.5 22.2 101.5 44.1 18.4 4.2 24.8 0.8 75.2 0.0 63.2 4.6 30.6 11.5 46.6 43.9 0.0 889.9 61.3 4.1 28.6 77.5 77.5 1.3 13.4 11.4 40.9 6.4 10.1 55.3 44.2 8.2 1.6 8.8 2.7 17.1 2.2 17.8 200.5 1.7 5.1 0.0 313.1 1278.1 124.2 53.8 18.0 1.0 115.8 68.7 13.4 25.9 0.7 59.2 20.1 41.5 11.3 8.9 27.0 38.1 26.8 3.4 14.1 56.6 157.0 PTPRR "EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ" ENSG00000153233 "Protein tyrosine phosphatase receptor type R" Q15256 12 70638073-70920738 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.4;endometrium 1: 5.5;intestine: 7.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 199.5;Inhibitory neurons: 160.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 3.6" "Group enriched" "Detected in many" 5 "amygdala: 3.7;basal ganglia: 5.7;cerebellum: 14.4;cerebral cortex: 6.5;hippocampal formation: 7.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HDLM-2: 20.0;RT4: 37.4" "Region enriched" "Detected in all" 5 "cerebellum: 89.6" "CAB011461, HPA011851, HPA071067" Uncertain Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 45: Intestine - Brush border" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions, Cytosol" "CAB011461: AB_298890, HPA011851: AB_1855939, HPA071067: AB_2686340" "unprognostic (4.98e-2)" "unprognostic (1.91e-2)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "unprognostic (3.63e-3)" "unprognostic (3.48e-5)" "unprognostic (5.44e-3)" "unprognostic (1.77e-3)" "unprognostic (1.13e-1)" "unprognostic (9.01e-2)" "unprognostic (1.37e-3)" "unprognostic (8.06e-2)" "unprognostic (1.10e-2)" "unprognostic (1.92e-2)" "unprognostic (4.78e-2)" "unprognostic (2.72e-1)" "prognostic favorable (1.40e-5)" 0.0 2.2 3.7 1.0 5.7 0.0 0.0 14.4 6.5 0.3 0.0 7.4 3.2 5.5 0.0 0.0 0.1 1.0 0.0 7.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.0 5.0 2.5 0.0 1.1 0.0 0.0 7.6 2.9 1.5 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.9 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 37.4 0.1 5.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 5.7 14.4 6.5 7.2 0.5 0.2 0.0 0.1 1.5 0.0 1.5 1.7 0.0 0.0 3.9 0.2 0.5 0.1 0.5 0.0 16.5 0.2 0.1 3.5 0.0 3.4 0.0 0.0 0.0 0.7 43.2 0.0 2.6 1.7 2.2 1.3 4.0 0.0 0.0 199.5 0.2 0.3 0.3 10.2 14.6 0.0 0.0 0.7 0.0 0.0 16.8 160.7 1.8 0.0 0.0 0.3 0.4 0.0 0.2 0.0 3.7 0.0 0.2 1.0 2.0 4.0 2.8 23.0 0.0 0.0 0.4 17.3 0.0 0.1 0.8 0.0 0.1 0.8 0.0 0.1 0.0 0.1 0.8 0.4 0.0 0.7 0.4 PTPRS ENSG00000105426 "Protein tyrosine phosphatase receptor type S" Q13332 19 5158495-5340803 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 76.8;Inhibitory neurons: 104.2;Melanocytes: 80.0;Oligodendrocytes: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 89 "plasmacytoid DC: 12.5" "Lineage enriched" "Detected in single" 89 "dendritic cells: 12.5" "Cell line enhanced" "Detected in many" "AN3-CA: 121.8;HaCaT: 124.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054747 Approved "Plasma membrane,Cytosol" "Secreted - unknown location" NA NA 150000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA054747: AB_2682591" "unprognostic (8.14e-2)" "unprognostic (4.59e-3)" "unprognostic (2.57e-2)" "unprognostic (9.20e-2)" "unprognostic (2.15e-1)" "unprognostic (6.96e-3)" "unprognostic (6.85e-2)" "unprognostic (2.36e-1)" "unprognostic (3.12e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (4.05e-1)" "unprognostic (3.46e-2)" 54.7 21.2 34.4 5.0 25.5 1.5 36.2 3.2 30.9 40.2 0.0 25.2 2.6 30.5 2.2 16.5 41.1 13.7 37.0 34.3 10.0 11.2 6.0 26.9 5.5 16.4 16.4 35.8 32.4 9.7 29.1 2.3 17.6 30.5 1.6 5.7 18.6 14.6 14.4 20.6 13.6 8.6 1.6 9.0 23.2 9.9 27.3 4.2 29.4 7.4 4.4 32.0 31.8 34.9 11.3 64.0 56.2 121.8 25.3 20.5 7.4 19.4 22.5 22.8 18.5 0.7 6.2 0.2 44.5 32.2 18.0 124.6 15.1 0.2 10.0 1.5 24.3 0.0 27.2 40.5 11.7 0.0 14.1 21.8 5.4 4.8 0.9 29.4 0.6 7.9 18.5 0.2 9.1 48.0 5.2 12.3 31.7 0.4 27.0 0.0 12.4 0.0 4.7 22.5 43.1 58.9 18.3 3.4 34.6 10.7 22.0 4.8 2.8 20.2 34.3 46.9 23.6 6.2 0.1 36.9 10.5 0.0 44.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 34.4 25.5 3.2 30.9 34.3 10.0 16.4 16.4 17.6 1.6 27.3 34.9 1.1 6.4 1.1 53.8 3.2 60.9 42.4 16.1 22.2 49.6 3.3 5.5 14.1 27.1 4.9 12.9 2.1 0.7 56.4 0.1 9.8 1.4 3.4 5.4 11.4 9.7 3.0 0.0 76.8 0.9 32.2 51.2 5.1 5.3 0.0 4.0 25.4 20.2 1.7 11.8 104.2 0.0 10.2 0.3 20.0 5.4 46.6 3.4 80.0 15.9 0.8 46.6 0.0 71.9 90.2 0.5 0.0 36.1 6.3 35.0 0.0 2.9 1.7 10.1 13.1 46.4 22.6 7.4 14.8 16.8 36.7 1.0 2.0 2.7 0.4 30.0 PVR "CD155, HVED, Necl-5, NECL5, PVS, Tage4" ENSG00000073008 "PVR cell adhesion molecule" P15151 19 44643798-44666162 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 4.5;intermediate monocyte: 4.5;myeloid DC: 3.8;non-classical monocyte: 5.5" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;monocytes: 5.5" "Cell line enhanced" "Detected in many" "TIME: 175.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012568, HPA064739" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" "Secreted - unknown location" NA NA 720000000 "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Vesicles, Plasma membrane" "HPA012568: AB_1846248, HPA064739: " "unprognostic (2.90e-3)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.36e-1)" "unprognostic (2.34e-1)" "unprognostic (7.89e-2)" "unprognostic (2.45e-3)" "unprognostic (3.06e-2)" "prognostic unfavorable (9.30e-4)" "unprognostic (9.05e-3)" "unprognostic (1.69e-1)" "unprognostic (2.09e-3)" "unprognostic (2.64e-3)" "unprognostic (1.69e-1)" "unprognostic (4.97e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-3)" "prognostic unfavorable (2.75e-4)" 13.9 17.5 10.2 7.1 9.1 5.1 9.6 9.0 10.0 8.7 9.3 10.3 12.5 13.9 5.2 8.4 11.8 6.2 28.5 9.0 16.6 13.6 30.7 19.4 2.7 9.7 11.0 12.5 14.0 10.3 17.3 12.5 12.4 9.7 8.8 5.4 9.9 6.4 19.0 7.1 11.1 10.5 7.4 4.6 12.3 5.8 14.9 2.5 10.6 6.2 2.8 9.1 8.5 7.9 58.8 52.1 5.6 25.0 8.6 9.7 7.4 96.7 38.8 40.7 45.8 31.9 28.2 0.1 50.6 43.7 60.2 44.4 24.3 51.1 31.7 7.8 27.1 8.8 40.3 23.3 43.7 4.1 22.2 10.6 28.0 40.9 82.5 49.7 50.7 6.6 4.3 0.5 23.4 7.8 4.2 5.8 12.5 30.1 31.7 0.1 23.2 5.0 111.8 25.5 21.2 22.9 66.3 54.3 14.7 7.2 22.8 12.5 175.3 39.0 52.8 33.7 78.2 0.3 6.3 0.2 35.3 23.4 24.6 0.2 4.5 0.0 0.1 4.5 0.0 0.0 0.0 0.2 3.8 0.0 0.2 0.1 1.1 0.7 5.5 0.5 0.0 1.7 10.2 9.1 9.0 10.0 9.0 16.6 9.7 11.0 12.4 7.4 14.9 7.9 11.1 16.0 25.2 2.3 1.6 3.6 16.0 6.9 4.0 5.7 4.7 3.4 14.4 14.3 12.2 1.8 2.1 2.9 0.2 18.5 3.9 37.9 10.5 5.4 6.3 20.4 13.1 2.1 11.4 35.3 34.8 7.7 13.7 11.6 1.3 6.5 7.9 41.1 8.4 1.7 13.7 11.3 2.0 8.9 7.5 14.3 5.6 6.8 1.8 5.6 17.2 1.8 2.1 6.0 4.6 69.6 18.0 15.8 0.2 14.4 10.8 5.7 2.8 3.4 0.0 23.8 10.4 10.4 1.5 5.8 5.5 1.0 0.9 10.8 12.7 7.4 PXK "FLJ20335, Slob" ENSG00000168297 "PX domain containing serine/threonine kinase like" Q7Z7A4 3 58332880-58426127 "Enzymes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 320.5" "Cell type enriched" "Detected in all" 9 "Oligodendrocytes: 732.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 159.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024068 Supported Supported "Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 32: U-937 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Plasma membrane, Centriolar satellite" "HPA024068: AB_1855967" "unprognostic (2.98e-2)" "unprognostic (3.29e-1)" "unprognostic (2.71e-3)" "unprognostic (1.61e-1)" "unprognostic (2.40e-1)" "unprognostic (6.62e-3)" "unprognostic (5.03e-3)" "prognostic favorable (5.68e-4)" "unprognostic (3.90e-1)" "unprognostic (8.09e-2)" "unprognostic (3.48e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-3)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" 19.9 16.7 71.6 31.5 161.3 73.1 15.8 112.3 109.2 46.7 20.4 23.3 10.6 23.5 8.4 11.3 17.5 15.5 17.8 84.1 115.0 18.2 11.6 20.6 43.0 158.2 131.3 18.3 15.7 21.2 13.4 29.7 154.1 12.8 10.5 35.6 14.8 11.7 18.8 14.3 19.3 18.7 82.1 25.2 16.3 12.4 119.0 13.7 63.1 14.3 44.9 19.5 30.2 320.5 13.7 6.9 6.8 12.0 79.7 70.0 17.8 22.6 42.5 19.7 27.3 4.0 3.1 74.7 5.1 33.6 28.4 4.2 18.7 13.2 21.8 18.5 12.5 13.1 11.3 5.8 87.5 112.8 22.5 57.4 31.6 24.6 42.0 72.5 17.8 49.1 15.7 26.1 35.7 5.3 26.2 122.2 7.8 4.1 19.7 40.7 9.4 13.4 12.6 8.0 6.0 4.0 14.2 11.0 19.0 10.7 34.8 122.9 17.9 24.9 11.0 48.5 23.9 19.4 21.6 73.7 36.2 159.3 10.7 39.5 44.6 69.1 23.8 37.2 20.7 62.6 17.1 20.3 41.8 69.6 15.3 17.5 73.5 21.6 57.1 32.1 21.1 32.0 71.6 161.3 112.3 109.2 84.1 115.0 158.2 131.3 154.1 82.1 119.0 320.5 20.1 9.6 6.3 28.4 59.8 14.1 5.8 5.6 7.4 31.0 5.9 7.1 13.1 7.2 6.0 23.9 20.9 19.7 31.7 8.3 33.2 7.1 69.7 9.1 33.0 14.2 7.8 19.3 33.8 5.7 6.8 41.5 6.1 16.0 19.7 15.2 16.4 7.5 13.6 20.2 53.7 5.0 2.0 24.5 31.1 38.3 30.7 25.2 17.8 30.0 28.6 32.7 30.9 79.4 732.6 3.0 5.5 25.2 17.6 6.0 8.7 12.2 6.4 22.2 19.7 18.7 18.2 16.8 21.9 10.1 13.1 35.2 16.9 18.3 5.0 3.9 PYGL GSD6 ENSG00000100504 "Glycogen phosphorylase L" P06737 14 50857891-50944483 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 145.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 151.2;Hofbauer cells: 177.6;Muller glia cells: 265.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 141.1;neutrophil: 153.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 279.1;HMC-1: 304.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000962, HPA004119" Enhanced Supported "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane, Cytosol" "HPA000962: AB_1079722, HPA004119: AB_1079723" "unprognostic (2.70e-2)" "unprognostic (8.64e-3)" "unprognostic (1.46e-2)" "unprognostic (8.55e-2)" "unprognostic (9.41e-2)" "prognostic unfavorable (5.97e-4)" "unprognostic (1.66e-1)" "unprognostic (1.34e-2)" "unprognostic (3.34e-1)" "unprognostic (1.94e-2)" "prognostic unfavorable (2.63e-4)" "unprognostic (4.45e-3)" "unprognostic (3.15e-3)" "unprognostic (1.95e-2)" "unprognostic (1.76e-1)" "unprognostic (9.72e-2)" "unprognostic (1.12e-3)" 110.1 21.0 5.9 24.1 6.6 108.9 36.4 5.0 8.4 33.6 10.4 19.0 3.7 20.7 6.4 55.8 19.1 13.0 14.9 5.2 6.2 10.2 145.6 26.1 6.3 10.7 17.6 18.2 5.7 21.1 7.5 49.3 8.7 13.0 24.0 78.2 26.8 29.7 5.1 37.0 8.4 26.7 8.6 49.4 9.6 5.2 9.0 4.8 10.2 5.8 6.8 41.7 38.1 10.3 145.7 40.8 10.1 64.3 47.0 56.2 114.5 28.6 24.1 77.4 117.3 107.4 18.3 0.1 54.4 171.7 91.2 279.1 107.0 144.8 132.0 0.5 46.8 28.0 60.5 82.4 83.8 106.9 304.4 119.4 56.8 104.1 43.6 75.4 69.3 0.8 11.6 0.5 55.4 144.7 0.4 141.7 39.3 12.8 152.0 2.7 36.2 6.1 104.7 95.1 4.5 4.4 131.0 43.3 1.7 38.6 20.6 200.4 3.2 29.7 49.6 56.0 92.9 1.2 0.3 0.5 27.3 107.7 15.9 50.2 55.9 141.1 0.0 24.2 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.0 153.7 0.6 15.7 1.2 0.2 24.8 5.9 6.6 5.0 8.4 5.2 6.2 10.7 17.6 8.7 8.6 9.0 10.3 6.7 22.4 6.3 1.3 1.8 30.7 10.5 40.5 6.8 4.6 7.0 3.8 3.4 5.7 35.4 7.3 0.0 28.9 0.2 11.2 3.9 10.9 1.0 35.4 18.9 7.8 1.2 9.0 1.8 2.1 151.2 18.8 6.6 62.6 6.3 9.3 8.2 65.4 177.6 1.7 2.2 7.1 14.2 56.7 7.9 1.5 14.3 54.6 19.6 15.9 52.4 265.1 2.1 14.1 0.6 7.4 5.2 21.8 1.8 9.7 0.0 6.4 24.5 11.9 6.6 15.4 8.8 0.7 1.4 22.4 22.3 21.1 2.3 4.0 14.0 9.2 RAB13 ENSG00000143545 "RAB13, member RAS oncogene family" P51153 1 153981617-153986358 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 7.0;myeloid DC: 10.5;plasmacytoid DC: 12.9" "Group enriched" "Detected in many" 11 "dendritic cells: 12.9;monocytes: 7.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 846.1" HPA003996 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA003996: AB_1079728" "unprognostic (4.39e-3)" "unprognostic (1.20e-1)" "unprognostic (2.51e-2)" "unprognostic (4.11e-2)" "unprognostic (4.28e-3)" "unprognostic (3.20e-2)" "unprognostic (1.18e-3)" "unprognostic (2.80e-1)" "unprognostic (3.53e-2)" "unprognostic (2.11e-2)" "unprognostic (2.10e-1)" "unprognostic (5.93e-2)" "unprognostic (1.06e-3)" "unprognostic (2.45e-1)" "unprognostic (1.03e-1)" "unprognostic (9.51e-3)" "unprognostic (1.28e-2)" 151.4 132.8 78.8 91.0 80.1 104.3 124.1 79.4 112.4 114.1 89.2 123.6 54.1 92.2 111.3 102.0 96.0 83.3 90.1 77.3 88.6 164.6 111.1 116.8 42.5 92.5 85.3 111.1 115.1 97.9 35.4 64.3 89.7 123.5 73.6 10.5 96.3 73.5 45.9 92.1 79.0 67.5 84.7 97.5 123.3 61.7 84.0 19.2 112.8 49.5 47.7 123.2 107.7 83.7 133.4 162.5 143.7 152.8 478.2 846.1 43.2 157.9 381.1 142.6 144.6 165.4 111.9 0.1 230.7 194.4 72.7 88.4 86.9 146.7 198.0 78.6 62.3 110.1 100.5 94.3 199.5 0.4 70.9 620.1 125.3 246.6 109.1 401.0 253.4 0.0 20.6 0.5 246.6 280.0 0.5 55.4 231.8 183.9 151.2 28.9 186.1 0.1 327.0 140.5 7.2 112.6 208.7 179.8 337.0 215.4 294.2 87.0 469.6 256.0 149.5 161.1 174.7 0.4 0.1 0.9 399.6 17.4 399.7 0.0 7.0 0.1 0.0 1.0 0.1 0.7 0.1 0.0 10.5 0.6 0.1 0.4 0.8 0.0 0.1 12.9 0.0 1.9 78.8 80.1 79.4 112.4 77.3 88.6 92.5 85.3 89.7 84.7 84.0 83.7 230.1 41.7 83.4 1.0 9.0 92.0 181.3 196.3 110.4 1.2 126.9 149.2 75.2 120.1 105.3 108.5 2.1 116.3 2.8 81.5 135.0 234.4 119.9 91.9 163.2 239.8 89.1 116.4 0.0 149.2 181.2 100.8 76.5 111.4 40.6 111.9 192.4 136.2 249.1 0.0 0.0 184.2 83.4 111.1 104.5 232.1 106.2 116.0 99.6 7.5 247.4 71.5 2.1 0.0 0.1 158.1 110.6 124.1 10.6 197.0 135.7 206.5 72.2 3.8 151.2 46.9 151.4 103.6 18.4 124.8 98.2 92.9 8.9 141.6 146.1 195.9 RAB8A "MEL, RAB8" ENSG00000167461 "RAB8A, member RAS oncogene family" P61006 19 16111889-16134234 "Predicted intracellular proteins" "Autophagy, Cilium biogenesis/degradation, Protein transport, Transport" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041945 Approved "Nucleoplasm,Plasma membrane" No No 4800000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane" "HPA041945: " "unprognostic (1.10e-1)" "unprognostic (3.95e-3)" "unprognostic (1.98e-2)" "unprognostic (2.59e-1)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (2.11e-1)" "unprognostic (2.57e-1)" "unprognostic (1.14e-2)" "unprognostic (2.52e-3)" "unprognostic (1.29e-2)" "prognostic unfavorable (6.56e-5)" "unprognostic (6.60e-2)" "unprognostic (7.25e-2)" "prognostic favorable (1.71e-4)" "unprognostic (9.99e-2)" 21.3 24.5 17.4 40.4 17.5 61.3 18.7 19.5 17.6 24.6 20.7 37.4 58.5 18.5 18.9 25.9 27.8 22.0 11.5 17.2 19.1 20.8 51.5 28.6 44.3 21.1 19.5 21.5 23.4 17.7 15.3 25.0 21.6 21.7 32.8 8.7 30.7 21.2 7.0 27.5 58.7 22.8 20.3 40.4 32.4 15.4 19.0 34.3 16.3 8.1 45.1 25.9 21.2 23.3 94.2 62.6 50.5 43.0 42.7 36.7 77.9 56.0 48.8 74.2 76.8 76.1 105.7 66.1 61.9 58.6 63.5 60.6 71.2 69.1 50.9 132.6 39.9 135.9 57.1 75.6 46.7 119.4 129.3 36.6 37.6 69.5 32.1 38.9 63.5 65.0 64.4 97.0 63.4 111.6 100.1 113.7 63.3 114.3 100.5 111.6 56.2 115.6 58.2 71.9 46.9 45.3 56.6 68.0 35.9 34.2 53.8 44.2 61.7 61.4 39.2 119.2 96.6 51.4 113.4 97.3 58.7 121.5 67.0 244.5 278.6 315.0 164.3 387.5 145.7 190.5 143.3 147.5 247.5 190.0 112.5 131.7 292.2 225.9 485.1 177.8 150.9 514.1 17.4 17.5 19.5 17.6 17.2 19.1 21.1 19.5 21.6 20.3 19.0 23.3 47.2 25.6 29.1 2.3 70.2 47.7 47.4 53.5 31.3 15.2 37.0 34.7 3.0 17.2 35.7 31.3 14.6 95.7 97.9 115.9 82.2 70.7 31.0 33.7 29.7 37.3 30.4 47.5 4.2 51.5 98.6 36.3 29.6 45.0 48.7 36.2 26.0 50.3 88.9 6.7 3.5 55.3 48.8 50.6 81.5 19.0 27.7 100.9 33.8 2.8 124.8 34.9 131.8 3.0 8.8 76.8 90.0 24.8 96.5 30.7 130.7 62.6 35.4 13.9 32.9 22.0 38.1 33.3 23.4 30.4 52.6 79.6 64.8 43.4 52.0 38.4 RAET1G ULBP5 ENSG00000203722 "Retinoic acid early transcript 1G" Q6H3X3 6 149916878-149923121 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.4;esophagus: 15.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 42.9;Club cells: 14.8;Ionocytes: 12.2;Respiratory ciliated cells: 23.3;Squamous epithelial cells: 8.9;Urothelial cells: 8.1" "Group enriched" "Detected in many" 4 "cervical cancer: 4.5;head and neck cancer: 4.7;lung cancer: 1.2;thyroid cancer: 1.5;urothelial cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 29.5;hTCEpi: 22.6;SiHa: 11.9;U-87 MG: 9.3" "HPA062673, HPA066741" Supported "Vesicles,Plasma membrane" "Secreted - unknown location" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "HPA062673: , HPA066741: " "unprognostic (4.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.87e-3)" "unprognostic (1.49e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (5.35e-4)" "unprognostic (3.05e-1)" "unprognostic (1.57e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.33e-1)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" "unprognostic (8.85e-2)" "unprognostic (9.11e-2)" 2.8 8.4 0.4 0.4 0.3 0.0 0.6 0.0 0.4 4.1 0.0 0.2 0.1 0.3 0.7 15.1 0.6 0.7 0.6 0.4 0.3 0.9 0.1 0.5 0.1 0.3 0.6 0.7 0.1 0.2 0.3 0.1 0.1 0.7 0.1 0.1 3.7 1.0 0.2 2.7 0.2 0.6 0.0 0.1 0.4 0.3 0.7 0.0 0.4 0.1 1.1 1.8 6.0 0.0 1.0 1.4 0.0 1.7 2.3 1.7 0.0 0.8 3.0 1.3 1.9 0.0 1.5 0.0 0.6 1.7 1.4 2.7 0.9 5.3 1.1 0.3 1.6 0.5 29.5 0.0 0.7 0.0 0.0 3.3 22.6 3.5 1.7 1.5 0.3 0.7 0.3 0.2 0.6 1.3 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 1.0 3.2 0.3 0.3 11.9 0.5 0.0 0.1 0.4 0.4 1.6 0.6 0.5 1.6 0.8 0.0 0.0 0.0 9.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.4 0.4 0.3 0.3 0.6 0.1 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 3.1 5.1 42.9 2.8 0.0 0.4 0.4 0.1 1.5 14.8 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.4 0.1 1.3 0.0 0.0 0.0 1.3 0.0 1.9 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 12.2 0.0 0.7 0.1 0.9 0.0 3.6 0.0 0.0 0.8 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.0 0.0 23.3 0.0 0.0 0.2 1.1 0.0 0.3 8.9 1.7 0.1 0.3 0.5 0.0 8.1 RAET1L ENSG00000155918 "Retinoic acid early transcript 1L" Q5VY80 6 150018334-150025532 "Predicted membrane proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 58.1;vagina: 17.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.4;Basal prostatic cells: 11.3;Basal respiratory cells: 6.4;Prostatic glandular cells: 7.1;Squamous epithelial cells: 7.2;Suprabasal keratinocytes: 17.0;Urothelial cells: 8.1" "Group enriched" "Detected in many" 4 "cervical cancer: 4.8;head and neck cancer: 10.1;lung cancer: 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HaCaT: 14.3" HPA066741 Supported "Vesicles,Plasma membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane" "HPA066741: " "unprognostic (1.80e-1)" "unprognostic (1.63e-1)" "unprognostic (2.15e-1)" "unprognostic (1.84e-1)" "unprognostic (4.24e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (8.34e-2)" "unprognostic (1.37e-1)" "unprognostic (2.26e-2)" "unprognostic (7.48e-2)" "unprognostic (1.46e-2)" "unprognostic (2.49e-1)" "unprognostic (1.29e-1)" "unprognostic (5.14e-2)" "unprognostic (7.43e-3)" 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 58.1 0.0 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.1 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.2 0.3 17.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 1.2 0.0 0.7 14.3 0.3 0.4 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.4 0.0 0.0 0.0 2.6 0.7 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.2 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 11.3 6.4 1.2 0.0 0.4 0.3 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.0 0.0 2.8 0.8 0.5 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 7.1 0.0 0.2 0.9 0.0 0.0 0.0 0.4 0.0 0.1 7.2 17.0 0.0 0.0 0.0 0.1 8.1 RAF1 "c-Raf, CRAF, Raf-1" ENSG00000132155 "Raf-1 proto-oncogene, serine/threonine kinase" P04049 3 12583601-12664125 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 175.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 175.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002639, HPA002640, CAB019291" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "CAB019291: , HPA002639: , HPA002640: AB_1856047" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (5.92e-2)" "unprognostic (2.17e-3)" "unprognostic (6.51e-3)" "unprognostic (7.66e-3)" "unprognostic (2.66e-3)" "unprognostic (1.53e-2)" "unprognostic (2.72e-1)" "unprognostic (7.66e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-2)" "unprognostic (2.79e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (2.36e-2)" 42.4 34.2 36.7 33.8 37.9 77.4 39.2 42.6 37.4 47.6 40.4 46.8 40.5 45.6 34.0 55.5 43.2 31.0 89.6 36.9 35.8 46.7 68.9 44.7 36.3 38.3 36.9 52.0 50.6 63.6 28.3 39.1 37.0 41.9 42.0 37.4 39.6 38.0 194.9 56.0 43.4 45.5 36.7 48.3 55.5 26.8 38.1 52.8 48.8 122.5 47.7 46.1 46.2 39.8 49.9 57.9 85.5 66.6 74.3 59.6 168.0 73.9 129.1 100.1 112.5 46.6 41.3 52.7 34.6 120.1 51.6 31.9 93.4 67.5 103.8 91.4 70.2 72.0 69.4 42.9 74.2 70.1 64.7 55.3 67.8 102.3 82.0 67.6 73.1 78.2 52.6 136.0 98.3 88.6 91.1 47.8 86.5 64.0 76.4 72.6 75.7 66.4 60.9 76.9 26.1 56.2 61.1 59.8 40.9 66.1 99.1 91.5 51.1 65.6 62.5 55.7 85.0 103.3 178.4 112.3 57.2 80.4 73.9 40.4 32.7 62.5 22.3 32.6 22.5 19.5 21.9 22.3 30.3 20.4 21.9 22.8 175.1 29.8 34.2 13.5 28.3 28.2 36.7 37.9 42.6 37.4 36.9 35.8 38.3 36.9 37.0 36.7 38.1 39.8 28.5 22.4 37.6 47.7 36.1 34.4 35.2 22.1 27.9 56.7 27.5 22.6 29.0 35.8 25.7 27.6 66.7 40.0 41.5 31.3 13.7 25.6 8.8 33.2 37.1 32.7 29.3 46.7 46.1 37.0 46.8 32.3 27.5 43.8 34.2 78.7 36.0 41.2 28.6 43.7 52.9 31.0 30.5 39.3 43.4 4.6 39.1 34.7 26.6 44.0 49.5 31.9 51.5 65.4 64.0 35.5 29.9 41.3 43.3 46.9 47.3 20.1 31.2 81.9 32.9 56.2 39.1 28.3 33.6 31.8 43.5 62.3 40.8 35.6 31.2 47.1 RALA RAL ENSG00000006451 "RAS like proto-oncogene A" P11233 7 39623565-39708120 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Exocytosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 292.4;Pancreatic endocrine cells: 411.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 302.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047037, HPA065232" Approved Supported "Plasma membrane,Focal adhesion sites" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "Focal adhesion sites" "HPA047037: , HPA065232: AB_2685440" "unprognostic (1.20e-3)" "unprognostic (1.03e-2)" "unprognostic (2.91e-1)" "unprognostic (7.73e-3)" "unprognostic (1.98e-2)" "unprognostic (9.14e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (7.71e-2)" "unprognostic (2.17e-1)" "prognostic favorable (7.46e-4)" "prognostic unfavorable (6.30e-4)" "unprognostic (3.32e-1)" "unprognostic (4.95e-3)" "unprognostic (5.38e-2)" "unprognostic (7.15e-2)" "unprognostic (2.79e-1)" "unprognostic (2.95e-2)" 27.8 32.1 32.4 20.7 35.5 7.4 23.8 35.8 37.3 23.0 30.2 30.9 32.6 20.4 20.1 54.0 19.6 26.8 17.6 33.7 34.3 20.6 21.4 41.8 21.4 37.0 35.7 22.2 16.0 22.6 10.5 32.5 36.4 15.4 31.6 13.0 19.8 15.8 25.8 26.9 30.9 21.1 37.7 18.8 33.8 12.7 34.9 25.5 17.4 19.1 35.2 23.5 22.0 39.8 81.0 18.3 44.1 38.6 81.7 67.6 30.0 69.7 99.7 61.8 67.9 46.1 39.0 41.5 25.5 54.1 58.1 81.5 62.5 45.0 105.5 40.2 29.6 32.4 28.1 34.1 132.1 56.9 43.8 53.7 54.0 110.0 155.4 76.7 302.4 39.7 65.9 27.0 63.2 26.3 40.3 66.7 123.0 88.0 35.9 49.4 40.2 36.3 63.1 37.3 78.0 75.6 42.8 67.7 49.4 78.7 63.5 60.9 98.0 36.4 32.4 46.3 50.7 47.6 39.1 50.3 40.5 58.0 67.2 38.3 13.5 15.7 12.5 15.6 15.7 15.8 20.1 16.2 22.6 18.0 25.6 22.9 6.1 23.2 12.6 14.5 28.1 15.9 32.4 35.5 35.8 37.3 33.7 34.3 37.0 35.7 36.4 37.7 34.9 39.8 66.5 83.3 38.1 25.5 40.5 90.1 37.3 75.1 41.5 14.6 41.3 63.5 37.3 40.0 50.3 23.9 6.2 52.1 28.4 80.1 21.5 165.4 98.2 56.5 64.8 121.5 47.8 35.1 47.6 122.0 92.5 52.4 42.3 99.9 31.7 41.8 75.0 27.8 101.9 11.8 48.4 53.1 144.5 33.0 292.4 17.4 47.8 73.0 30.2 44.0 97.0 37.3 23.7 39.2 37.0 411.0 73.8 69.6 48.6 61.0 70.8 38.6 36.6 16.6 32.9 26.5 131.9 59.1 71.6 113.4 109.4 62.0 37.0 53.9 58.7 64.5 RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 144.6" "Group enriched" "Detected in many" 12 "Adipocytes: 287.8;Endothelial cells: 366.0;Hepatic stellate cells: 555.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "Karpas-707: 2.5" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 174.9;white matter: 60.0" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075527: " "unprognostic (1.62e-3)" "prognostic favorable (2.89e-4)" "unprognostic (4.85e-2)" "unprognostic (6.88e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "prognostic favorable (2.50e-6)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-1)" "unprognostic (2.79e-2)" "unprognostic (9.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (9.21e-2)" 86.9 32.6 17.7 23.0 19.7 0.2 71.7 26.9 22.7 33.5 21.3 24.4 10.2 25.9 3.9 18.9 22.8 28.7 91.3 19.2 25.8 84.1 23.9 144.6 55.0 37.3 25.7 7.4 19.7 28.1 22.3 8.6 34.2 29.7 8.6 1.1 22.1 12.9 19.3 22.8 30.0 24.4 31.6 11.4 25.7 6.3 23.5 7.3 71.9 26.9 30.3 28.5 30.5 42.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 17.7 19.7 26.9 22.7 19.2 25.8 37.3 25.7 34.2 31.6 23.5 42.4 287.8 0.0 1.9 0.3 3.6 16.3 0.3 0.0 2.2 0.6 5.9 2.8 8.7 1.5 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 20.8 0.4 7.3 366.0 0.0 13.5 3.5 0.7 0.1 10.7 0.0 0.2 0.0 0.0 555.4 7.3 0.5 0.0 0.2 0.0 0.0 31.2 19.1 6.7 1.2 1.3 26.6 5.6 0.0 0.2 0.0 0.0 6.5 0.0 0.0 1.2 1.3 0.6 0.0 0.0 0.0 0.5 0.0 2.8 4.9 0.3 0.9 0.9 14.5 0.0 1.7 1.5 0.0 0.5 RAPGEF2 "DKFZP586O1422, KIAA0313, PDZ-GEF1, PDZGEF1, RA-GEF" ENSG00000109756 "Rap guanine nucleotide exchange factor 2" Q9Y4G8 4 159103013-159360174 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, GTPase activation, Guanine-nucleotide releasing factor" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 456.2;Inhibitory neurons: 264.1;Microglial cells: 238.9;Oligodendrocyte precursor cells: 199.0;Oligodendrocytes: 236.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 5.9" "Group enriched" "Detected in many" 5 "granulocytes: 5.9;NK-cells: 3.3" "Cell line enhanced" "Detected in many" "HMC-1: 104.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068798 Supported "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA068798: " "unprognostic (4.88e-2)" "unprognostic (7.42e-2)" "unprognostic (1.67e-2)" "unprognostic (7.79e-3)" "unprognostic (8.16e-2)" "unprognostic (4.71e-3)" "unprognostic (4.20e-3)" "unprognostic (2.33e-1)" "unprognostic (2.17e-1)" "unprognostic (2.65e-2)" "unprognostic (9.71e-2)" "unprognostic (1.07e-1)" "prognostic favorable (1.76e-7)" "unprognostic (2.29e-1)" "unprognostic (2.07e-1)" "unprognostic (2.01e-2)" "unprognostic (1.78e-1)" 22.7 9.4 8.7 13.4 19.8 87.5 24.1 4.1 32.1 16.7 0.0 21.8 15.9 16.1 9.8 13.8 14.0 20.1 23.2 27.4 0.3 22.7 30.5 26.6 11.9 0.0 0.7 13.5 19.5 23.5 15.3 38.5 0.3 12.2 20.8 35.1 25.3 12.6 21.7 17.5 17.0 19.7 0.6 29.7 19.3 9.8 6.0 17.5 39.5 31.4 11.5 14.8 11.8 18.6 8.9 11.9 55.4 17.2 21.4 23.9 84.9 17.0 21.3 15.2 10.9 36.7 19.4 50.7 6.1 17.0 22.0 8.0 19.1 21.8 18.0 8.6 13.2 79.0 25.3 21.4 15.5 9.7 104.5 14.1 12.1 36.5 12.9 32.0 44.1 20.7 17.6 46.0 19.0 15.6 24.1 1.5 23.7 10.4 11.8 19.7 14.0 2.0 13.6 20.2 15.7 21.0 24.9 12.1 20.0 26.5 6.0 6.3 47.0 23.9 25.2 30.7 14.2 51.0 32.9 0.8 28.3 4.1 14.8 2.2 1.0 0.7 0.5 0.5 0.6 0.2 0.4 0.3 0.5 0.2 0.6 0.3 5.9 3.3 0.6 1.0 1.0 0.3 8.7 19.8 4.1 32.1 27.4 0.3 0.0 0.7 0.3 0.6 6.0 18.6 66.7 57.7 30.1 110.7 12.9 20.4 11.2 7.5 9.6 19.7 23.5 11.9 39.0 11.5 13.8 7.3 41.7 11.1 20.2 24.8 0.0 9.2 5.3 43.5 19.5 49.2 14.4 38.9 456.2 12.6 9.6 16.9 7.7 59.2 51.8 22.9 32.2 30.5 10.8 33.7 264.1 12.0 2.0 24.6 20.1 5.3 7.8 29.5 33.8 238.9 15.6 30.2 2.1 199.0 236.2 22.1 17.7 8.6 40.5 17.6 7.1 8.7 18.7 22.4 52.6 28.1 37.2 3.5 8.9 10.7 20.0 5.9 12.9 7.2 7.9 15.1 RAPH1 "ALS2CR18, ALS2CR9, KIAA1681" ENSG00000173166 "Ras association (RalGDS/AF-6) and pleckstrin homology domains 1" Q70E73 2 203394345-203535335 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 61.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 84.0;Hepatic stellate cells: 103.5;Microglial cells: 92.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016744, HPA020027" Approved Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA 69000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Nuclear bodies, Plasma membrane" Cytosol "HPA016744: AB_1844781, HPA020027: AB_1844782" "unprognostic (9.78e-2)" "unprognostic (9.05e-2)" "unprognostic (7.17e-4)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (8.32e-2)" "unprognostic (6.31e-2)" "unprognostic (1.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.24e-4)" "unprognostic (1.92e-1)" "unprognostic (1.40e-2)" "unprognostic (5.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (2.79e-1)" 11.1 6.5 1.5 5.2 4.6 3.1 13.3 1.3 7.9 9.4 0.3 7.0 7.8 5.6 4.6 8.8 5.1 8.9 5.9 5.0 8.5 7.2 61.6 14.3 3.7 2.4 7.0 2.0 6.4 5.6 3.6 13.0 4.1 6.6 7.3 7.3 8.6 4.3 6.6 8.9 7.9 7.8 0.1 16.9 8.8 9.4 2.7 2.6 30.0 6.2 4.9 7.7 6.6 2.2 11.1 7.5 15.6 9.0 12.0 15.4 14.7 15.1 11.0 15.3 19.1 35.0 11.4 0.0 3.7 23.1 11.2 5.8 8.2 12.9 31.7 2.2 4.6 0.0 17.9 6.2 30.0 0.1 0.2 21.5 10.7 28.1 29.4 16.8 24.2 1.7 0.8 8.2 31.0 6.2 0.1 0.0 9.2 5.7 10.0 0.2 22.0 6.9 11.2 34.9 5.5 7.5 10.3 9.8 12.5 20.4 5.5 0.5 29.0 37.5 12.5 18.2 16.1 3.8 7.7 0.1 30.9 0.2 8.4 0.0 0.2 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.1 0.0 1.5 4.6 1.3 7.9 5.0 8.5 2.4 7.0 4.1 0.1 2.7 2.2 36.3 16.0 8.4 12.7 1.2 49.1 20.7 10.3 16.5 11.3 21.6 9.4 1.1 15.7 9.7 14.7 14.6 8.9 0.8 32.9 7.9 6.3 14.4 24.4 17.7 29.0 2.4 3.2 84.0 9.3 7.6 23.4 47.9 65.7 1.3 6.2 103.5 79.6 18.1 10.1 56.7 8.6 4.1 17.8 51.1 4.9 4.7 28.8 12.4 92.8 3.3 18.6 0.0 41.2 9.1 20.5 21.3 4.9 0.1 19.0 22.4 2.8 5.2 4.4 19.7 26.8 33.4 29.3 19.6 26.9 40.9 10.9 2.8 0.9 13.3 28.4 RASAL3 FLJ21438 ENSG00000105122 "RAS protein activator like 3" Q86YV0 19 15451624-15464544 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 23.5;intestine: 19.8;lung: 10.6;lymphoid tissue: 39.4" "Cell type enhanced" "Detected in many" "B-cells: 39.4;dendritic cells: 70.9;granulocytes: 39.3;NK-cells: 139.0;T-cells: 76.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 30.6;HEL: 25.5;HMC-1: 46.7;Karpas-707: 52.5;NB-4: 27.8;RPMI-8226: 23.5;TIME: 35.5;U-937: 34.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043417 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" "HPA043417: AB_2678473" "unprognostic (2.72e-2)" "prognostic favorable (8.75e-4)" "unprognostic (3.27e-2)" "prognostic favorable (3.58e-5)" "unprognostic (2.31e-1)" "prognostic favorable (3.07e-4)" "unprognostic (1.82e-2)" "unprognostic (6.21e-3)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (3.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (2.98e-1)" "unprognostic (1.90e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" 3.7 2.6 2.8 17.3 2.9 23.5 1.9 3.1 3.6 1.8 2.9 4.2 4.5 1.5 0.7 2.8 2.2 3.6 1.4 2.9 3.2 3.7 3.6 10.6 32.8 4.2 3.3 0.9 1.4 1.2 1.5 1.0 3.9 2.8 2.3 0.1 3.5 0.9 0.7 1.5 19.8 1.2 4.1 39.4 5.4 0.5 4.2 23.8 3.8 0.4 19.4 4.2 2.3 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 6.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 30.6 0.0 25.5 0.0 0.0 0.4 20.4 46.7 0.1 0.0 0.0 0.0 0.0 0.2 8.0 0.0 52.5 0.0 0.4 10.9 27.8 0.0 0.0 0.0 3.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 8.7 35.5 0.0 0.0 0.0 0.0 0.4 10.1 15.1 0.0 34.1 0.1 6.4 2.3 12.9 18.4 4.7 10.7 3.1 11.7 20.4 3.4 3.5 9.7 11.8 3.4 12.4 12.8 4.2 9.2 5.5 2.8 2.9 3.1 3.6 2.9 3.2 4.2 3.3 3.9 4.1 4.2 5.2 4.1 3.2 5.6 0.0 39.4 0.3 0.0 0.3 0.0 0.0 2.0 2.2 2.5 2.8 1.4 0.0 0.0 0.2 70.9 0.0 0.0 0.2 0.7 5.4 0.4 5.4 0.0 7.4 0.1 0.6 0.2 1.0 2.6 0.4 39.3 0.0 3.9 4.6 11.3 0.0 0.1 0.0 0.0 11.6 3.5 1.7 0.0 17.2 0.0 13.1 14.2 0.1 139.0 0.5 0.1 0.2 0.0 1.2 23.7 0.2 0.0 1.5 5.7 0.1 0.0 0.5 1.5 0.4 0.6 0.3 0.6 0.4 76.7 1.0 0.2 0.1 RASGRP1 "CalDAG-GEFII, RASGRP" ENSG00000172575 "RAS guanyl releasing protein 1" O95267 15 38488103-38565575 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7;lymphoid tissue: 45.7;retina: 29.7" "Cell type enhanced" "Detected in many" "dendritic cells: 71.4;Excitatory neurons: 54.1;Muller glia cells: 86.9;Plasma cells: 43.0;T-cells: 84.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 10.3" "Lineage enriched" "Detected in many" 4 "T-cells: 10.3" "Group enriched" "Detected in many" 4 "HDLM-2: 54.5;JURKAT: 70.2;MOLT-4: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039389 Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA039389: AB_2732481" "unprognostic (3.44e-3)" "unprognostic (1.86e-2)" "unprognostic (1.17e-2)" "unprognostic (3.43e-3)" "unprognostic (1.82e-2)" "unprognostic (3.33e-3)" "unprognostic (9.63e-2)" "unprognostic (4.23e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" "unprognostic (4.50e-1)" "unprognostic (3.01e-2)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (1.51e-1)" "unprognostic (3.40e-1)" "unprognostic (9.30e-2)" 1.1 0.8 6.7 10.5 16.8 8.5 1.7 23.7 13.2 0.8 0.0 1.4 2.4 1.4 0.4 5.9 4.4 2.5 1.2 11.6 3.3 5.5 1.1 4.1 21.4 15.3 2.5 0.4 1.8 0.5 0.5 0.9 17.9 0.7 2.1 29.7 1.7 0.7 0.4 6.9 3.6 0.6 0.0 8.9 4.5 2.0 8.8 45.7 0.6 0.7 16.4 3.4 2.0 9.2 0.0 0.4 1.0 0.3 0.0 0.0 0.1 4.1 1.2 2.0 1.7 4.5 0.0 11.6 0.9 0.1 0.2 0.2 2.4 0.0 1.9 54.5 2.2 0.9 0.5 0.0 0.6 0.5 0.8 0.0 0.1 1.1 0.0 0.0 0.0 70.2 0.5 3.6 0.0 1.7 52.3 0.1 0.7 0.0 0.0 14.4 0.3 0.0 2.0 0.1 4.7 1.7 2.6 0.1 0.2 1.5 1.2 0.0 0.2 0.4 1.6 5.6 0.8 8.7 4.6 13.6 0.2 0.1 0.6 0.0 0.0 0.9 5.2 0.0 3.7 1.1 5.7 5.2 0.0 0.6 5.2 5.3 0.2 2.4 0.0 0.0 10.3 1.4 6.7 16.8 23.7 13.2 11.6 3.3 15.3 2.5 17.9 0.0 8.8 9.2 0.9 6.4 10.7 6.5 26.5 2.4 0.4 6.8 4.6 9.6 3.4 2.0 4.5 5.7 2.7 33.1 10.4 0.3 71.4 0.1 3.9 18.4 1.5 7.6 1.6 0.8 0.0 0.0 54.1 10.0 0.2 1.2 1.1 6.6 3.8 0.4 1.1 0.5 0.7 6.7 16.5 1.3 0.0 0.8 6.1 0.7 0.0 3.0 7.2 9.4 3.0 86.9 34.0 2.5 3.9 34.1 0.0 0.0 43.0 0.7 0.3 7.8 0.4 21.3 0.0 1.9 1.3 1.2 3.8 4.0 8.2 0.0 84.7 0.3 0.9 0.5 RASGRP2 CALDAG-GEFI ENSG00000068831 "RAS guanyl releasing protein 2" Q7LDG7 11 64726911-64745456 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 147.3;lymphoid tissue: 140.5" "Cell type enhanced" "Detected in many" "B-cells: 125.5;dendritic cells: 86.1;Kupffer cells: 77.3;Macrophages: 72.2;NK-cells: 98.9;Sertoli cells: 131.5" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 103.4;HL-60: 192.8;NB-4: 347.1;REH: 105.0;THP-1: 108.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015635, HPA015667" Approved Supported "Plasma membrane" NA NA 1900000 "Cluster 37: B-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA015635: , HPA015667: AB_1856090" "unprognostic (5.96e-2)" "unprognostic (3.24e-3)" "unprognostic (5.55e-2)" "unprognostic (1.50e-2)" "unprognostic (3.52e-2)" "unprognostic (4.74e-5)" "unprognostic (1.11e-2)" "unprognostic (7.36e-3)" "unprognostic (2.02e-1)" "unprognostic (3.33e-1)" "unprognostic (4.91e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.08e-1)" "unprognostic (5.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.23e-1)" 23.8 10.1 16.1 52.9 35.5 147.3 16.8 9.6 22.4 20.1 7.1 37.5 6.6 28.3 4.6 9.1 29.2 8.7 51.7 13.4 13.4 15.8 10.1 29.5 106.0 12.4 16.3 9.1 4.1 1.0 5.5 10.9 11.9 23.2 5.3 1.3 4.6 18.6 12.2 6.1 86.4 15.0 9.5 140.5 17.5 11.9 20.7 34.6 10.6 10.2 62.0 26.7 15.5 9.8 0.1 0.1 3.0 0.1 0.0 0.3 8.7 1.3 0.2 1.2 0.8 1.5 0.2 62.8 2.7 0.2 0.8 0.7 5.4 0.9 0.3 0.3 1.7 103.4 0.0 0.4 0.3 192.8 35.9 0.0 0.0 0.5 0.0 0.0 0.1 25.9 4.1 1.1 0.0 1.4 45.4 347.1 2.5 0.4 0.0 105.0 0.2 4.4 0.0 0.0 0.5 2.3 0.1 0.1 0.0 2.2 0.6 108.5 0.6 0.0 2.0 1.5 0.1 0.5 0.1 58.9 0.0 58.2 0.0 64.4 34.1 59.9 70.4 88.0 37.3 170.7 72.9 57.2 34.5 100.2 92.7 83.1 70.9 55.3 105.8 85.9 93.8 67.5 16.1 35.5 9.6 22.4 13.4 13.4 12.4 16.3 11.9 9.5 20.7 9.8 27.4 3.2 1.8 2.6 125.5 2.3 0.1 0.0 0.0 2.6 1.6 3.7 53.1 2.8 0.0 0.0 0.0 1.7 86.1 0.1 0.0 0.0 6.6 1.9 27.1 13.5 0.0 24.2 6.0 0.0 1.3 6.6 2.6 1.2 3.8 5.7 31.4 1.7 6.1 0.0 12.2 0.1 0.0 77.3 19.7 19.5 18.0 72.2 0.0 6.5 55.8 0.7 98.9 2.5 0.9 0.0 0.0 47.8 28.6 0.1 0.4 0.9 0.7 2.5 131.5 5.4 56.8 18.0 43.9 0.9 1.3 11.8 61.0 0.8 0.3 0.2 RASGRP4 ENSG00000171777 "RAS guanyl releasing protein 4" Q8TDF6 19 38409051-38426305 "Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 20.8;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 18.1;granulocytes: 26.6;Hofbauer cells: 15.1;Kupffer cells: 32.9;Langerhans cells: 11.6;Macrophages: 19.1;monocytes: 25.7" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 39.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 25.7;HMC-1: 24.0;U-937: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041929 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041929: AB_10961405" "unprognostic (1.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-2)" "unprognostic (1.39e-2)" "unprognostic (2.10e-1)" "unprognostic (2.00e-1)" "unprognostic (5.23e-4)" "unprognostic (6.54e-2)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (2.19e-2)" "unprognostic (1.05e-1)" "unprognostic (4.56e-1)" "unprognostic (2.66e-2)" 3.2 0.8 0.3 6.7 0.3 20.8 0.7 0.3 0.9 1.1 0.4 1.2 1.2 0.5 0.1 1.0 1.0 1.9 0.6 0.2 0.3 0.3 0.7 3.3 1.1 0.9 0.4 0.4 1.1 0.3 0.2 2.3 0.6 0.5 0.8 0.0 0.4 0.5 0.8 0.5 1.8 2.0 0.7 8.9 0.9 0.2 1.1 1.1 0.2 1.4 0.7 2.5 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 25.7 0.0 0.0 0.0 0.1 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 12.5 13.5 20.1 0.0 15.4 0.0 0.1 0.3 0.0 9.4 0.1 0.0 0.0 39.4 0.0 17.9 0.7 1.4 4.4 0.3 0.3 0.3 0.9 0.2 0.3 0.9 0.4 0.6 0.7 1.1 1.0 0.2 0.0 0.6 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.0 0.3 18.1 0.0 1.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.8 0.7 0.0 0.2 0.4 0.0 0.0 26.6 0.0 1.4 0.0 15.1 0.0 0.4 0.0 0.0 32.9 11.6 0.0 0.0 19.1 1.8 0.0 25.7 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.7 0.0 0.4 0.4 0.0 0.1 0.0 0.0 0.3 1.5 0.0 0.0 0.1 RC3H1 "KIAA2025, RNF198, roquin, RP5-1198E17.5" ENSG00000135870 "Ring finger and CCCH-type domains 1" Q5TC82 1 173931084-174022357 "Enzymes, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027428, HPA027434, HPA027448" Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Cytosol "Golgi apparatus, Plasma membrane" "HPA027428: AB_10600324, HPA027434: AB_10601235, HPA027448: AB_10601683" "unprognostic (6.91e-2)" "unprognostic (7.76e-2)" "unprognostic (2.23e-2)" "unprognostic (2.33e-2)" "unprognostic (7.73e-2)" "unprognostic (1.61e-2)" "unprognostic (5.74e-2)" "unprognostic (1.99e-2)" "unprognostic (1.75e-1)" "unprognostic (1.13e-2)" "unprognostic (2.04e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (5.25e-2)" "unprognostic (2.15e-1)" "unprognostic (3.43e-3)" "unprognostic (6.83e-3)" 4.8 3.8 2.6 4.2 4.7 19.6 5.2 16.0 5.1 4.9 11.4 5.2 3.4 4.5 4.0 6.1 4.8 4.0 4.6 3.1 5.8 3.9 5.8 5.9 4.9 3.5 3.5 5.1 4.8 3.9 4.6 4.3 4.0 4.2 4.2 8.0 4.4 3.5 10.6 7.4 5.5 3.7 2.0 6.7 4.6 5.3 4.1 5.0 5.0 10.3 5.6 4.5 5.1 7.2 6.6 9.1 4.9 7.7 9.2 7.1 6.8 4.4 6.3 5.0 4.4 8.4 7.3 9.4 7.7 7.2 3.9 6.2 7.5 6.3 7.0 6.6 1.8 8.1 6.8 7.0 5.6 10.7 9.1 6.8 4.8 7.3 4.9 4.6 7.9 4.5 9.4 5.6 6.2 5.0 6.5 9.6 8.5 6.1 1.0 7.0 8.8 6.9 8.9 12.7 5.9 5.3 8.4 10.7 4.3 8.2 7.2 10.7 11.4 6.5 6.5 5.6 5.8 6.9 7.5 11.8 4.4 4.8 6.7 3.4 1.9 2.7 1.1 1.9 1.2 1.5 1.1 1.3 1.0 1.8 1.5 1.3 6.4 1.4 2.6 0.8 0.9 0.7 2.6 4.7 16.0 5.1 3.1 5.8 3.5 3.5 4.0 2.0 4.1 7.2 39.8 41.7 34.5 32.0 49.4 34.4 17.3 14.1 60.9 35.6 53.6 28.3 25.7 25.8 20.0 23.9 81.3 10.6 70.2 37.4 9.8 25.4 13.3 77.5 45.9 32.0 34.2 30.7 46.8 18.9 8.2 34.9 68.8 82.9 15.8 20.3 34.2 36.3 11.5 38.7 43.5 28.9 16.2 37.2 48.2 8.1 15.8 38.5 30.2 40.3 33.0 22.7 30.9 42.3 68.2 24.8 22.1 10.5 52.2 38.3 25.1 9.8 30.2 47.3 19.7 39.0 31.5 35.8 14.0 66.8 40.9 11.6 41.4 16.1 25.9 38.5 RDX DFNB24 ENSG00000137710 Radixin P35241 11 109864295-110296712 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin capping, Actin-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 155.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 484.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, HPA000763, CAB037312" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 38000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Nucleoplasm "CAB037312: AB_261933, HPA000263: AB_1856043, HPA000763: AB_1856042" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (3.85e-1)" "unprognostic (2.74e-2)" "unprognostic (6.93e-2)" "unprognostic (9.82e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (3.91e-2)" "unprognostic (6.91e-2)" "unprognostic (1.32e-3)" "unprognostic (6.47e-2)" "unprognostic (4.14e-3)" "unprognostic (5.43e-2)" "unprognostic (4.40e-1)" "unprognostic (1.24e-1)" "unprognostic (1.08e-3)" 40.3 155.0 38.0 17.4 57.7 12.0 16.4 50.0 42.7 32.1 32.8 15.2 6.8 28.8 12.9 27.4 19.7 27.2 41.0 35.1 44.7 50.2 68.5 48.8 11.4 52.7 48.2 52.8 52.7 33.2 7.6 35.3 54.3 25.4 11.1 19.2 20.8 26.0 82.1 11.9 7.4 35.0 45.1 26.6 15.0 33.7 47.7 14.3 45.7 59.7 14.6 27.1 10.1 77.6 69.6 35.3 137.3 54.8 78.8 87.4 79.3 85.8 47.6 54.3 59.2 99.7 115.4 0.1 127.4 104.7 84.9 61.5 77.3 80.4 80.5 41.9 44.2 51.5 107.7 74.1 73.6 19.0 33.2 89.7 45.6 68.0 120.1 89.3 149.8 11.1 73.5 29.5 127.0 120.0 11.0 15.6 44.0 4.0 58.4 31.2 96.8 30.1 68.1 33.5 37.2 40.5 148.5 65.9 52.7 102.5 85.0 29.9 92.6 89.5 66.8 43.9 67.4 9.5 17.3 65.9 34.2 11.3 210.9 29.5 14.8 22.0 11.6 12.5 15.5 11.5 10.2 8.8 12.8 8.3 6.8 5.8 2.0 17.6 9.9 10.3 22.0 8.4 38.0 57.7 50.0 42.7 35.1 44.7 52.7 48.2 54.3 45.1 47.7 77.6 248.8 484.0 98.8 53.5 30.0 56.1 51.8 124.6 56.9 85.9 47.4 45.7 159.3 70.1 77.9 75.4 43.8 122.1 21.6 17.7 109.5 128.1 15.5 109.1 117.2 289.2 22.2 104.8 27.1 423.4 189.8 88.4 19.9 135.3 67.2 132.0 319.2 260.1 85.1 101.0 57.6 7.3 61.1 103.2 59.9 43.6 275.2 71.6 72.9 42.2 135.4 77.0 36.0 68.3 229.4 134.3 22.1 266.7 36.1 65.9 0.1 236.9 52.2 94.8 124.9 74.0 143.8 73.9 257.4 52.8 40.5 227.3 29.2 229.9 11.8 45.9 RECK "hRECK, ST15" ENSG00000122707 "Reversion inducing cysteine rich protein with kazal motifs" O95980 9 36036913-36124455 "Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Protease inhibitor, Serine protease inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 63.1;Inhibitory neurons: 71.1;Oligodendrocyte precursor cells: 80.4;Oligodendrocytes: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 199.5;ASC TERT1: 158.5;BJ: 65.1;BJ hTERT+: 93.0;fHDF/TERT166: 57.8;HSkMC: 71.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025109, HPA071729" Supported Supported "Plasma membrane" NA NA 64000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025109: , HPA071729: AB_2686438" "unprognostic (3.42e-1)" "unprognostic (4.01e-3)" "unprognostic (5.50e-2)" "unprognostic (5.05e-4)" "unprognostic (8.87e-2)" "unprognostic (8.47e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.75e-2)" "unprognostic (1.51e-2)" "unprognostic (9.06e-2)" "unprognostic (8.48e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (7.31e-4)" "unprognostic (2.68e-2)" "unprognostic (1.50e-2)" "unprognostic (3.60e-2)" 14.7 7.4 3.0 4.6 3.3 1.2 13.7 3.4 4.3 15.2 2.7 6.8 3.7 14.4 6.1 11.7 8.0 13.7 8.5 4.6 3.3 5.7 5.8 12.7 5.8 3.4 3.1 14.3 3.2 3.7 3.1 11.3 3.5 8.3 6.3 4.7 4.7 7.3 3.7 7.6 5.1 14.7 3.1 7.3 5.7 3.2 3.4 6.6 6.2 16.0 4.4 12.1 7.5 4.0 1.4 2.4 8.0 4.4 199.5 158.5 0.1 65.1 93.0 4.7 11.0 0.0 0.0 2.5 6.0 57.8 3.7 0.4 1.8 1.2 6.4 4.1 3.7 2.6 2.8 0.2 16.2 0.3 11.1 71.3 1.6 7.1 2.7 18.4 14.6 4.8 0.0 2.1 12.2 0.3 6.6 1.0 2.7 0.0 2.0 6.9 6.2 0.0 3.2 0.2 0.7 4.5 1.5 0.8 2.7 8.3 0.0 8.9 44.4 9.0 3.3 5.9 3.6 2.9 3.4 2.7 5.5 8.7 5.8 1.0 2.6 0.7 3.9 2.8 4.4 1.2 5.2 4.2 2.9 2.7 6.3 4.6 0.3 3.0 4.8 1.6 2.6 2.3 3.0 3.3 3.4 4.3 4.6 3.3 3.4 3.1 3.5 3.1 3.4 4.0 12.8 3.2 5.4 40.1 11.7 7.1 4.0 5.0 4.6 12.5 4.2 5.6 3.6 1.5 2.5 3.7 14.6 0.9 9.3 0.2 0.0 6.6 38.3 0.9 11.6 19.6 6.1 5.7 63.1 1.5 7.7 53.4 3.6 0.6 9.5 9.2 25.4 1.1 15.6 8.4 71.1 1.3 4.1 15.7 15.9 35.5 18.6 8.3 3.6 41.2 8.8 14.3 2.1 80.4 119.8 1.3 0.4 17.7 5.9 4.3 0.3 1.6 4.1 7.8 0.0 14.2 15.3 41.2 27.4 1.3 7.5 0.8 10.2 7.8 0.8 1.2 RELL1 ENSG00000181826 "RELT like 1" Q8IUW5 4 37590800-37686376 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.7" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Microglial cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 59.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013377 Approved Supported "Plasma membrane,Microtubules" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Microtubules" "HPA013377: AB_1844403" "unprognostic (1.70e-1)" "unprognostic (1.70e-1)" "unprognostic (4.78e-2)" "unprognostic (5.30e-2)" "unprognostic (6.80e-2)" "unprognostic (7.28e-2)" "unprognostic (7.35e-2)" "unprognostic (2.67e-2)" "unprognostic (2.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (7.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (6.15e-2)" "unprognostic (1.71e-2)" 13.5 2.4 10.6 4.9 15.5 25.6 7.8 20.1 14.9 5.1 9.3 8.3 6.2 5.5 2.7 6.4 5.1 6.1 6.0 8.0 13.3 3.9 4.8 6.6 4.7 29.7 19.3 3.5 2.3 1.5 1.4 6.1 27.7 3.0 6.6 3.1 3.5 3.8 15.8 12.4 5.5 6.0 24.4 7.3 12.3 1.6 20.1 3.7 12.5 4.3 4.8 7.8 4.1 39.7 4.8 5.1 12.9 11.1 10.8 6.2 10.8 8.0 6.9 5.5 7.2 16.8 5.7 1.3 5.7 6.9 9.8 4.3 4.1 7.2 9.6 0.2 2.1 1.8 4.7 18.2 8.1 6.0 4.5 10.6 10.2 7.5 8.2 3.4 24.9 3.3 3.1 5.0 6.4 4.4 7.5 8.3 3.2 6.9 1.5 2.5 45.0 2.2 13.2 5.9 2.9 8.5 6.1 6.6 10.6 3.2 18.0 3.2 29.6 13.8 8.7 10.1 9.5 2.5 2.6 7.3 11.7 12.8 11.4 0.8 15.2 27.4 5.1 5.7 6.3 0.7 6.2 4.9 8.5 0.2 5.3 7.0 59.3 7.7 5.5 9.8 5.5 5.1 10.6 15.5 20.1 14.9 8.0 13.3 29.7 19.3 27.7 24.4 20.1 39.7 30.5 9.6 3.1 16.3 2.9 3.3 2.5 1.7 10.8 0.4 8.1 9.5 2.1 5.7 3.9 0.0 0.0 1.4 9.8 8.4 0.0 3.1 6.5 5.5 9.9 14.4 1.2 3.4 3.3 8.6 3.6 10.7 22.4 2.4 2.5 0.5 6.4 0.9 2.6 3.3 2.4 1.6 0.0 3.2 2.7 8.1 3.7 9.2 1.8 36.5 4.1 4.0 0.0 22.6 12.5 10.3 2.9 6.0 15.5 2.7 6.7 0.2 3.3 1.4 13.1 18.8 16.4 0.8 0.3 5.5 4.7 5.2 10.6 5.1 1.1 3.8 RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077064-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 20.8;brain: 27.3;parathyroid gland: 31.8" "Group enriched" "Detected in some" 4 "Horizontal cells: 79.1;Ionocytes: 26.4;Skeletal myocytes: 23.1" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 74.6;NB-4: 42.2;SH-SY5Y: 329.3;THP-1: 95.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 53.3;spinal cord: 19.4" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" No NA 2100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" 1.8 20.8 1.0 1.3 0.9 0.4 1.1 5.1 5.6 1.0 0.2 3.4 1.4 0.6 0.3 0.4 0.5 0.6 2.2 0.3 5.5 0.9 3.0 0.4 0.6 14.4 27.3 0.4 1.3 31.8 5.3 0.5 12.0 1.8 1.4 4.7 5.1 2.0 5.9 0.9 1.4 1.0 4.8 0.2 2.2 2.7 7.6 1.6 0.8 3.1 0.2 0.6 1.4 5.8 0.1 0.4 0.1 1.7 0.0 0.0 0.1 0.7 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 7.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.6 0.0 42.2 7.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.7 329.3 0.1 0.0 0.1 0.5 4.1 95.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.1 0.0 1.0 0.9 5.1 5.6 0.3 5.5 14.4 27.3 12.0 4.8 7.6 5.8 0.4 0.0 0.5 1.6 0.0 0.3 0.8 0.0 0.0 1.7 6.0 0.5 2.1 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.0 0.0 1.5 0.0 0.3 1.1 0.0 0.0 4.2 0.2 2.3 6.8 0.0 0.0 1.3 0.5 0.0 1.2 0.1 79.1 8.6 1.9 26.4 0.0 0.6 1.5 0.3 0.5 0.0 1.0 0.0 0.8 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.8 1.7 0.0 23.1 1.2 1.1 4.7 0.0 0.6 0.0 0.2 0.3 0.2 0.1 RGS10 ENSG00000148908 "Regulator of G protein signaling 10" O43665 10 119499817-119542719 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 222.9" "Cell type enhanced" "Detected in many" "granulocytes: 291.2;Hofbauer cells: 528.1;Kupffer cells: 297.2;Langerhans cells: 358.3;Macrophages: 529.3;monocytes: 294.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 474.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004559, HPA021305, HPA058485" Enhanced Supported Supported "Nucleoplasm,Plasma membrane" NA NA 840000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane" "CAB004559: AB_628216, HPA021305: AB_1856225, HPA058485: AB_2683732" "unprognostic (1.64e-2)" "prognostic favorable (6.81e-4)" "unprognostic (7.98e-2)" "prognostic favorable (6.32e-4)" "unprognostic (5.21e-2)" "unprognostic (6.19e-2)" "unprognostic (4.32e-3)" "unprognostic (6.35e-2)" "unprognostic (9.90e-3)" "unprognostic (1.10e-1)" "unprognostic (1.42e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.20e-10)" "unprognostic (2.50e-1)" "unprognostic (9.20e-2)" "unprognostic (7.70e-2)" "unprognostic (7.92e-3)" 25.1 20.6 20.0 59.3 20.2 74.5 40.7 22.3 30.4 63.9 22.3 114.3 34.2 38.5 15.8 51.5 28.5 38.3 13.4 20.7 24.5 18.8 11.4 28.1 119.0 28.6 24.5 22.5 7.0 6.9 13.8 45.6 28.9 43.2 49.7 2.6 41.0 20.3 31.5 22.9 58.3 42.8 26.1 48.7 30.0 4.9 26.1 222.9 33.0 11.6 96.5 50.3 45.8 37.2 165.2 31.2 2.4 294.7 41.4 262.6 25.9 74.9 118.1 45.3 73.5 9.8 38.7 66.8 38.1 60.9 45.7 35.4 44.3 48.2 123.8 32.0 42.8 183.1 8.9 24.2 63.1 40.0 474.0 100.7 63.1 88.3 84.4 159.4 88.2 65.4 47.6 58.5 55.0 79.2 221.9 134.8 13.5 21.2 71.1 43.8 0.3 26.1 24.7 40.4 10.8 9.3 14.4 192.6 285.3 36.3 35.1 71.7 108.3 25.4 21.9 36.1 67.8 2.7 46.0 27.0 7.6 166.5 11.4 184.8 116.0 1.4 77.9 151.4 82.9 36.0 169.6 134.9 224.3 21.7 397.5 303.3 52.5 44.3 130.4 133.2 202.3 372.5 20.0 20.2 22.3 30.4 20.7 24.5 28.6 24.5 28.9 26.1 26.1 37.2 10.4 0.0 13.1 2.6 60.3 36.8 25.7 104.5 27.9 0.2 68.9 96.6 1.1 1.5 39.7 1.8 0.0 14.0 70.1 7.1 60.7 0.8 2.1 89.8 25.1 12.7 18.7 156.6 0.2 6.4 34.8 68.6 11.2 53.6 291.2 101.2 13.2 1.5 528.1 0.0 1.8 85.7 32.6 297.2 358.3 5.1 50.1 529.3 94.3 67.5 294.5 1.8 50.4 0.5 0.2 9.9 10.0 9.4 32.1 88.8 3.3 5.2 24.6 0.8 13.1 14.4 31.8 0.3 9.3 39.6 28.1 10.1 164.7 3.5 19.3 41.4 RGS3 "C2PA, FLJ20370, PDZ-RGS3" ENSG00000138835 "Regulator of G protein signaling 3" P49796 9 113444731-113597743 "Plasma proteins, Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 111.6;Horizontal cells: 158.2;Proximal tubular cells: 195.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 248.4;HDLM-2: 413.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044234 Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA044234: " "prognostic unfavorable (9.93e-4)" "unprognostic (4.04e-2)" "unprognostic (5.33e-3)" "unprognostic (6.71e-3)" "unprognostic (1.49e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (6.62e-4)" "unprognostic (6.79e-2)" "unprognostic (9.17e-2)" "unprognostic (2.24e-1)" "unprognostic (8.59e-3)" "unprognostic (3.04e-1)" "unprognostic (2.51e-3)" "unprognostic (1.52e-2)" "unprognostic (1.45e-1)" "unprognostic (8.53e-2)" "unprognostic (2.90e-1)" 60.5 31.5 32.0 18.1 37.3 9.3 43.7 33.7 29.7 17.9 49.7 30.4 16.9 20.8 11.4 10.8 15.2 42.4 95.0 24.0 31.5 70.9 54.5 64.2 23.9 32.2 44.3 10.3 23.9 12.3 16.6 32.3 32.5 26.3 15.8 10.3 10.8 10.2 48.2 15.2 20.0 18.0 28.2 31.9 27.6 31.2 58.0 7.9 24.5 19.2 11.4 26.5 15.4 34.0 4.5 16.6 40.1 37.0 12.2 18.1 2.9 41.2 248.4 32.9 27.9 40.8 14.7 17.9 29.7 33.6 32.8 10.6 0.6 16.0 19.2 413.2 0.1 1.7 13.0 24.8 24.8 0.4 5.5 32.4 16.6 91.4 13.2 72.6 125.4 1.0 0.3 17.1 60.5 18.7 1.2 1.9 10.6 28.6 13.7 1.3 19.8 2.9 67.7 8.1 31.3 4.2 3.9 31.3 24.7 19.6 21.5 3.8 61.2 109.7 11.8 5.1 79.1 8.6 1.5 2.7 126.2 3.8 51.6 10.2 6.8 3.7 24.7 7.1 16.7 2.4 5.7 20.3 6.6 2.4 2.4 10.8 18.5 42.3 6.0 0.3 3.8 15.6 32.0 37.3 33.7 29.7 24.0 31.5 32.2 44.3 32.5 28.2 58.0 34.0 49.5 16.0 13.9 14.4 5.6 12.0 9.9 7.4 4.6 1.4 9.1 10.7 55.8 72.9 8.4 22.0 6.2 4.6 23.5 28.0 82.2 65.1 38.8 9.9 14.9 111.6 0.0 6.1 2.4 30.4 3.7 29.3 27.0 4.0 47.7 12.8 66.0 35.2 15.6 158.2 3.4 7.4 4.1 14.3 13.8 17.4 4.7 14.6 55.2 21.5 10.3 3.5 50.4 3.5 24.4 31.0 23.4 13.9 4.5 5.0 20.5 195.7 7.5 6.4 6.6 8.4 35.4 9.9 1.8 4.1 11.4 3.0 18.4 55.5 11.5 12.9 RHEX "C1orf186, FLJ16052" ENSG00000263961 "Regulator of hemoglobinization and erythroid cell expansion" Q6ZWK4 1 206053173-206102449 "Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.4" "Group enriched" "Detected in some" 14 "Endometrial ciliated cells: 202.9;Glandular and luminal cells: 337.5;granulocytes: 334.3" "Group enriched" "Detected in many" 5 "endometrial cancer: 42.8;ovarian cancer: 41.1;renal cancer: 27.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 152 "basophil: 1312.1" "Lineage enriched" "Detected in single" 1544 "granulocytes: 1312.1" "Cell line enriched" "Detected in some" 5 "HMC-1: 1562.9" "Low region specificity" "Detected in all" HPA037859 Supported "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA037859: AB_10697084" "unprognostic (9.26e-3)" "unprognostic (1.91e-2)" "unprognostic (9.66e-2)" "unprognostic (1.65e-2)" "unprognostic (2.06e-2)" "unprognostic (5.27e-3)" "unprognostic (9.55e-2)" "unprognostic (3.04e-3)" "unprognostic (2.36e-1)" "unprognostic (1.31e-2)" "unprognostic (1.35e-1)" "unprognostic (7.20e-3)" "unprognostic (1.89e-2)" "unprognostic (3.02e-2)" "unprognostic (1.35e-1)" "unprognostic (3.77e-2)" "unprognostic (2.80e-3)" 4.1 0.4 0.0 2.9 0.0 1.3 4.7 0.0 0.0 24.4 0.0 7.5 3.3 12.8 16.3 7.7 5.3 16.3 0.9 0.0 0.0 14.3 0.9 10.7 4.1 0.0 0.0 0.2 1.4 0.3 0.4 0.6 0.0 2.8 7.4 0.0 2.8 20.0 1.0 4.5 6.7 7.3 0.0 3.0 6.4 1.0 0.1 3.1 2.0 2.5 4.6 7.7 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 143.8 0.0 0.9 0.0 75.2 1562.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 5.9 330.8 0.0 0.0 0.0 0.1 0.2 0.7 20.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.5 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.6 0.9 1.1 0.8 1312.1 0.0 8.6 0.0 0.1 0.1 0.5 0.2 0.0 0.6 0.2 0.1 0.2 0.5 0.0 0.2 0.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.6 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 20.2 0.0 2.3 0.7 0.0 1.9 3.6 0.0 202.9 17.6 1.3 0.0 0.0 0.0 0.2 0.2 0.4 0.0 337.5 334.3 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 5.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 RHOA "ARH12, ARHA, Rho12, RHOH12" ENSG00000067560 "Ras homolog family member A" P61586 3 49359139-49412998 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Host-virus interaction" Hydrolase "Cancer-related genes, Disease variant, Ectodermal dysplasia, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005052 Approved Supported "Plasma membrane,Cytosol" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB005052: AB_562216" "unprognostic (1.50e-1)" "unprognostic (3.38e-1)" "prognostic favorable (3.08e-4)" "unprognostic (8.75e-2)" "unprognostic (1.63e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.15e-4)" "unprognostic (1.39e-1)" "unprognostic (8.83e-2)" "unprognostic (9.44e-3)" "unprognostic (2.21e-2)" "unprognostic (4.29e-2)" "prognostic favorable (3.21e-6)" "unprognostic (5.14e-2)" "unprognostic (7.50e-2)" "unprognostic (1.57e-1)" "unprognostic (4.52e-2)" 452.4 315.0 234.6 357.9 258.6 473.4 360.0 257.1 274.1 310.4 237.4 351.9 274.6 293.8 298.6 362.6 269.2 267.1 269.6 220.8 271.2 286.9 274.5 430.9 396.3 282.9 245.8 297.2 225.3 269.4 164.3 396.8 287.2 244.5 369.3 113.3 238.0 315.6 331.0 281.3 281.0 416.9 259.3 329.1 292.1 154.1 257.5 387.7 326.3 298.5 454.9 358.2 273.6 292.5 470.4 406.1 500.9 512.7 569.9 858.9 370.8 930.1 735.7 790.3 722.4 347.6 527.4 721.8 251.6 1404.1 448.8 259.5 560.4 630.6 817.6 505.7 323.3 678.8 488.0 416.0 604.2 647.9 472.8 668.2 437.8 643.2 508.1 799.7 1038.0 391.9 361.1 437.9 967.5 254.3 717.3 739.0 441.4 548.2 497.1 325.5 451.4 610.5 701.9 559.6 167.7 387.3 599.0 464.5 495.4 499.4 301.7 819.6 972.1 558.4 483.2 737.2 725.7 388.0 775.6 754.8 567.9 691.6 678.3 716.9 1105.5 1160.5 480.1 1358.8 423.8 432.7 415.6 479.6 806.9 379.3 314.5 397.1 1282.7 440.9 1398.1 645.5 554.9 1884.8 234.6 258.6 257.1 274.1 220.8 271.2 282.9 245.8 287.2 259.3 257.5 292.5 502.8 387.8 265.2 20.5 374.6 270.9 260.0 236.1 251.6 47.1 239.4 223.1 141.1 178.7 220.9 180.3 6.2 355.8 373.1 447.2 340.4 339.5 48.2 174.2 243.7 413.8 234.4 319.3 26.1 347.8 709.8 386.2 313.9 201.0 257.3 141.6 312.7 173.2 760.0 82.4 27.0 344.9 191.2 771.9 495.8 55.6 335.2 683.7 327.3 52.5 710.0 219.9 389.3 24.6 51.4 398.0 354.6 407.7 375.7 334.1 341.3 350.8 201.1 40.8 276.1 354.1 450.1 264.4 253.6 390.8 279.6 525.2 359.5 299.1 347.7 371.4 RND1 "ARHS, Rho6, RHOS" ENSG00000172602 "Rho family GTPase 1" Q92730 12 48857145-48865870 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 131.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 205.5;Ductal cells: 220.6;Exocrine glandular cells: 147.1;Pancreatic endocrine cells: 350.9" "Cancer enhanced" "Detected in many" "liver cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "SK-BR-3: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077800 Supported "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 30: Non-specific - Translation" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Vesicles, Plasma membrane, Actin filaments" "HPA077800: AB_2686854" "unprognostic (5.60e-2)" "unprognostic (3.21e-2)" "unprognostic (2.23e-1)" "unprognostic (1.16e-1)" "unprognostic (6.90e-2)" "unprognostic (1.32e-3)" "unprognostic (3.59e-2)" "unprognostic (7.43e-2)" "unprognostic (2.21e-3)" "unprognostic (2.97e-1)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (3.89e-1)" "unprognostic (8.38e-3)" "unprognostic (6.18e-2)" "unprognostic (6.60e-2)" "unprognostic (3.35e-3)" 9.6 0.8 24.4 2.6 26.9 1.8 5.6 18.9 40.6 1.6 15.4 4.8 2.4 3.9 1.0 3.1 2.7 14.5 7.3 26.8 20.4 4.4 131.8 37.9 1.0 21.4 23.6 1.2 2.8 2.4 8.0 1.2 21.9 6.5 1.9 1.7 3.9 0.8 1.0 1.6 2.6 2.4 19.9 0.8 23.4 0.9 22.1 2.4 15.4 0.6 2.3 14.0 2.7 23.2 1.1 7.9 3.8 2.0 0.8 0.0 0.6 0.0 0.4 1.2 1.3 4.9 1.7 6.0 1.4 0.0 0.4 0.1 3.1 0.3 0.7 1.8 1.9 0.8 0.0 3.0 0.4 1.8 1.1 0.0 0.2 0.6 0.8 0.0 2.0 3.9 0.2 6.0 0.0 10.2 0.9 0.5 8.9 13.6 0.5 1.9 0.4 2.6 1.1 1.5 0.0 1.0 0.2 67.7 0.3 9.1 6.9 0.4 0.2 0.0 0.7 0.0 0.9 2.9 5.4 10.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 24.4 26.9 18.9 40.6 26.8 20.4 21.4 23.6 21.9 19.9 22.1 23.2 28.9 28.9 205.5 5.9 8.5 11.5 8.4 14.1 9.1 2.5 37.5 25.4 3.8 18.6 27.5 1.8 8.4 1.1 9.0 21.7 0.0 220.6 0.4 4.5 2.0 87.3 31.5 2.7 10.6 147.1 0.7 10.5 55.5 12.6 15.2 0.8 6.1 10.9 1.2 0.0 2.7 11.4 18.3 0.8 24.1 0.0 0.0 6.6 14.2 1.0 6.4 3.0 0.0 7.1 1.0 350.9 42.2 0.4 6.5 19.5 11.1 1.7 7.7 3.6 0.0 5.8 16.7 0.8 1.6 4.3 10.5 1.5 9.9 0.6 5.4 8.6 RNF146 "dactylidin, dJ351K20.1, DKFZp434O1427" ENSG00000118518 "Ring finger protein 146" Q9NTX7 6 127266682-127288567 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027158, HPA027209" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA027158: AB_10600772, HPA027209: AB_10602312" "unprognostic (8.22e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-1)" "unprognostic (1.38e-2)" "unprognostic (1.17e-2)" "unprognostic (1.37e-1)" "unprognostic (5.47e-3)" "unprognostic (1.87e-1)" "unprognostic (6.74e-2)" "prognostic favorable (5.26e-5)" "unprognostic (2.65e-2)" "prognostic favorable (7.32e-4)" "unprognostic (4.04e-2)" "unprognostic (1.29e-1)" "unprognostic (6.13e-2)" "unprognostic (2.15e-2)" 52.9 37.0 49.5 32.4 56.0 10.6 42.7 79.4 61.2 48.1 36.2 40.5 21.9 57.4 60.8 25.3 42.4 38.6 46.9 50.7 51.6 37.1 31.8 38.7 35.1 53.2 52.1 49.5 23.3 40.0 33.3 51.8 56.8 31.7 30.9 48.1 31.2 34.5 114.9 29.5 31.1 45.9 55.2 47.1 29.9 31.3 52.5 24.3 47.1 91.5 33.3 36.9 34.3 61.5 13.2 16.2 60.3 53.6 54.7 54.3 22.2 43.5 69.0 22.8 32.4 21.3 19.3 23.6 30.3 35.7 36.2 16.4 18.1 20.4 32.9 27.6 16.0 30.3 21.8 30.0 54.0 18.0 20.6 47.6 42.1 26.1 51.1 52.5 40.6 23.2 33.0 22.5 50.7 25.2 17.9 32.0 22.1 8.1 17.1 22.6 15.7 12.1 32.4 14.3 36.0 36.6 17.1 23.6 27.7 35.5 16.1 60.8 48.3 39.7 13.1 41.8 31.7 32.3 22.0 15.6 30.5 31.0 38.5 27.5 30.0 26.6 14.3 32.4 14.7 17.4 12.2 16.3 22.8 17.9 11.0 15.5 37.0 19.8 40.1 11.7 15.0 16.1 49.5 56.0 79.4 61.2 50.7 51.6 53.2 52.1 56.8 55.2 52.5 61.5 24.6 35.3 29.3 35.6 23.7 17.7 14.3 15.1 18.8 34.7 16.9 14.7 38.9 31.5 16.7 9.2 4.2 29.0 14.7 13.5 41.1 28.0 52.5 15.7 29.5 30.5 20.4 12.8 53.5 15.8 27.2 50.6 7.1 11.5 22.2 28.1 31.4 30.5 26.3 30.3 54.5 12.1 38.7 68.4 24.6 45.4 69.6 29.9 46.2 42.2 31.1 41.1 28.8 56.3 76.5 18.0 17.0 66.5 9.3 26.3 15.7 51.7 23.9 20.9 32.9 36.2 31.9 41.7 24.9 15.0 20.0 38.4 20.8 36.0 10.9 25.9 RP2 "NM23-H10, NME10, TBCCD2" ENSG00000102218 "RP2 activator of ARL3 GTPase" O75695 X 46837043-46882358 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 49.5" "Cell type enhanced" "Detected in many" "Kupffer cells: 62.8;Langerhans cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000234, HPA000909" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane" "Nuclear bodies" "HPA000234: AB_1079831, HPA000909: AB_2666140" "unprognostic (2.26e-1)" "unprognostic (6.01e-3)" "unprognostic (2.79e-2)" "unprognostic (2.98e-1)" "unprognostic (1.69e-1)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.97e-4)" "unprognostic (2.58e-2)" "unprognostic (9.76e-3)" "unprognostic (3.10e-2)" "unprognostic (3.79e-3)" "unprognostic (9.75e-2)" "unprognostic (6.15e-3)" "unprognostic (2.96e-2)" "unprognostic (9.66e-2)" "unprognostic (1.61e-1)" "unprognostic (4.28e-3)" 10.9 8.9 1.9 15.6 2.3 49.5 7.2 2.6 2.3 7.9 3.6 10.1 10.6 6.9 4.0 12.9 6.8 12.7 4.8 1.7 2.7 6.7 13.2 11.8 12.9 3.3 2.8 6.5 4.6 7.4 1.7 25.2 3.5 6.7 10.5 4.2 4.4 5.3 2.0 5.3 11.0 9.0 3.5 13.2 8.1 4.0 2.3 9.8 6.1 3.6 11.2 10.4 4.2 4.6 21.8 10.3 20.4 11.0 15.7 19.4 48.0 27.4 21.5 23.8 23.9 44.6 18.2 25.8 10.7 29.3 20.1 14.0 19.8 20.0 32.1 11.5 11.5 13.9 11.7 10.7 17.9 29.2 46.4 15.1 13.0 18.8 10.1 13.3 30.5 11.4 6.2 13.1 27.0 1.9 18.1 26.8 12.5 14.8 19.5 22.9 27.9 13.8 15.3 22.0 7.4 10.0 24.4 14.9 12.4 36.2 16.8 27.1 27.1 18.3 13.6 29.1 9.8 4.9 6.8 15.4 9.5 20.4 19.5 62.6 22.6 35.5 6.1 30.8 5.0 10.3 4.9 5.3 22.6 9.6 6.0 5.7 43.5 7.6 36.3 7.6 6.1 12.2 1.9 2.3 2.6 2.3 1.7 2.7 3.3 2.8 3.5 3.5 2.3 4.6 9.6 9.6 7.4 3.9 18.9 15.8 3.2 6.1 15.4 3.1 7.8 6.1 1.7 7.2 5.1 9.2 2.1 23.2 12.0 28.6 0.0 4.7 2.8 15.8 14.5 8.6 3.6 10.3 3.1 5.3 6.4 10.3 12.8 14.9 12.0 4.0 12.5 20.1 24.3 0.0 4.0 9.4 2.0 62.8 72.9 1.7 5.6 44.7 21.4 6.5 36.6 3.6 6.2 12.1 5.9 11.6 13.4 5.7 13.2 8.2 9.8 3.6 14.5 5.5 6.6 7.7 10.5 7.8 4.6 36.4 14.9 38.2 11.4 4.7 10.5 13.6 RPSA "37LRP, LAMR1, LRP, p40, SA" ENSG00000168028 "Ribosomal protein SA" P08865 3 39406716-39412542 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor, Ribonucleoprotein, Ribosomal protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" CAB009561 Approved Supported "Plasma membrane,Cytosol" NA NA 1200000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Plasma membrane, Cytosol" "CAB009561: AB_2182543" "unprognostic (3.67e-3)" "unprognostic (2.92e-1)" "unprognostic (3.97e-2)" "unprognostic (3.72e-2)" "unprognostic (5.38e-2)" "unprognostic (5.10e-2)" "unprognostic (5.84e-3)" "unprognostic (2.54e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (8.56e-2)" "unprognostic (7.50e-2)" "unprognostic (2.91e-2)" "unprognostic (3.18e-1)" "unprognostic (2.77e-1)" "unprognostic (1.73e-1)" "unprognostic (1.46e-1)" 1063.0 929.1 813.4 685.7 824.8 1574.8 1068.4 782.0 979.1 1260.0 761.8 1158.4 605.8 1022.1 351.0 1922.5 1128.3 372.5 783.9 778.6 794.3 905.9 972.5 894.3 1281.4 817.8 809.6 2153.7 2616.3 605.5 813.4 468.8 812.9 1212.6 872.2 273.3 1039.7 446.9 1087.1 1529.4 1133.1 718.3 842.4 1525.8 1209.3 358.0 831.9 1259.9 862.6 730.4 1466.4 1127.5 1293.1 821.5 1800.4 1646.5 1367.5 2265.9 1203.3 2661.2 2155.0 1251.2 2005.9 2775.9 1611.8 1811.6 1513.7 3949.6 737.0 2535.3 747.6 695.4 2983.8 2945.7 2402.3 1459.6 1599.6 1783.6 1390.5 1750.2 2322.7 2546.4 1649.2 3043.3 4729.8 2147.2 3475.3 2030.8 2942.7 2343.5 1909.3 1883.8 2031.1 1282.1 3031.0 1960.4 4574.2 2756.9 2755.1 1412.2 1958.4 2974.8 2004.4 814.2 985.3 1989.0 674.8 5156.5 2202.9 1843.5 1509.0 3544.5 1156.6 845.2 1545.8 1422.3 3102.3 1440.6 2363.4 2437.5 1355.7 2481.7 1143.9 98.3 240.5 56.7 572.9 294.6 993.1 1010.3 942.1 758.8 654.2 951.8 1036.2 936.1 34.3 726.0 247.5 723.6 765.5 1499.7 813.4 824.8 782.0 979.1 778.6 794.3 817.8 809.6 812.9 842.4 831.9 821.5 532.1 519.2 800.2 10.7 2802.5 1802.5 2606.9 1585.5 2040.3 270.4 1864.7 1423.4 64.0 1095.2 906.4 325.5 95.9 2852.5 1768.9 625.4 992.0 1598.4 144.3 536.7 1178.5 891.2 1033.6 1733.9 21.3 3417.4 4473.1 927.1 821.6 747.7 778.4 1654.5 937.3 717.7 1608.4 173.3 21.5 1847.0 455.7 1304.9 1469.6 283.7 1240.5 1086.9 738.2 12.2 1605.2 621.1 1858.9 19.1 29.3 1889.5 1184.2 747.4 1501.8 2136.7 724.4 1257.1 476.2 364.4 473.3 1053.5 1002.2 352.2 1255.8 2879.8 1916.2 2420.7 2100.0 1539.2 2442.4 2884.6 RRP12 KIAA0690 ENSG00000052749 "Ribosomal RNA processing 12 homolog" Q5JTH9 10 97356358-97426076 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 90.9;skeletal muscle: 38.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 26.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049945, HPA074403" Supported "Nucleoli,Vesicles,Plasma membrane,Cytosol" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Nucleoli "Vesicles, Plasma membrane, Cytosol" "HPA049945: AB_2680965, HPA074403: " "unprognostic (2.79e-1)" "unprognostic (7.65e-2)" "unprognostic (5.87e-3)" "unprognostic (1.10e-1)" "unprognostic (3.42e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.12e-8)" "unprognostic (2.64e-1)" "unprognostic (1.30e-2)" "unprognostic (1.54e-1)" "unprognostic (3.94e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (2.54e-5)" "unprognostic (2.58e-2)" "unprognostic (3.32e-1)" "unprognostic (4.81e-2)" "unprognostic (6.99e-3)" 8.1 10.2 2.6 9.2 3.4 90.9 5.6 1.1 7.6 5.6 2.4 4.9 6.0 7.4 3.6 8.5 7.3 7.2 11.4 3.2 2.7 6.8 5.7 6.7 6.7 4.3 4.4 6.1 16.0 9.3 10.2 4.3 4.1 6.3 3.8 3.4 8.3 4.0 38.5 10.3 4.7 6.0 0.2 7.6 6.3 10.9 3.7 4.7 5.5 9.7 6.1 9.3 5.7 4.6 38.9 50.8 13.2 28.6 10.0 11.6 28.9 24.2 14.4 24.2 18.7 55.6 35.0 42.3 30.4 15.1 21.6 48.7 36.3 28.0 16.3 23.1 44.2 32.8 19.5 43.6 16.5 51.7 41.5 12.2 38.6 59.9 54.6 27.0 13.7 23.5 47.7 27.4 14.0 50.8 35.0 33.0 57.0 20.4 34.0 38.1 18.0 42.1 16.8 21.4 17.7 37.9 19.2 18.1 24.1 10.4 43.7 26.5 18.2 16.1 27.9 36.5 76.4 55.7 52.7 48.6 23.2 64.9 17.9 0.4 11.2 6.9 2.7 13.6 3.3 3.9 1.6 2.2 6.2 4.2 2.5 2.8 26.7 1.9 16.9 5.0 1.2 6.0 2.6 3.4 1.1 7.6 3.2 2.7 4.3 4.4 4.1 0.2 3.7 4.6 8.8 35.3 31.1 5.9 18.5 23.5 14.2 5.1 25.0 5.8 12.7 9.9 11.6 7.2 21.5 14.7 41.7 5.2 7.7 10.6 0.0 8.7 7.2 17.1 10.6 10.6 21.5 7.2 15.1 8.7 7.5 13.5 27.0 20.1 41.7 12.9 3.9 8.9 11.5 5.0 9.5 13.8 4.1 12.5 7.1 4.8 3.7 30.3 7.2 2.8 12.3 1.9 3.1 5.0 4.4 8.5 6.4 2.6 31.8 17.1 3.7 6.8 24.6 12.7 0.0 19.4 6.7 10.6 20.6 22.7 19.6 9.2 11.0 13.5 11.5 13.6 RTN4R NOGOR ENSG00000040608 "Reticulon 4 receptor" Q9BZR6 22 20241415-20283246 "Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3;liver: 12.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.1;Excitatory neurons: 14.1;Muller glia cells: 11.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 8.0;basal ganglia: 20.0;cerebellum: 20.9;cerebral cortex: 24.3;hippocampal formation: 12.7" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.8" "Lineage enriched" "Detected in many" 9 "T-cells: 10.8" "Cell line enhanced" "Detected in many" "NB-4: 38.2;REH: 53.9;SCLC-21H: 31.3;SK-MEL-30: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012443 Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 1900000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Focal adhesion sites" "Actin filaments" "CAB012443: " "unprognostic (1.28e-1)" "unprognostic (1.28e-2)" "unprognostic (8.29e-2)" "unprognostic (6.58e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.19e-1)" "unprognostic (1.56e-1)" "unprognostic (3.44e-1)" "unprognostic (8.90e-3)" "unprognostic (1.21e-2)" "unprognostic (9.89e-2)" "unprognostic (1.80e-2)" "unprognostic (1.34e-2)" "unprognostic (1.30e-1)" "unprognostic (5.02e-2)" "unprognostic (3.07e-1)" 1.6 2.6 8.0 0.5 20.0 0.6 1.0 20.9 24.3 3.6 0.0 1.6 2.2 5.1 0.0 3.5 1.9 0.1 2.7 12.7 0.0 2.1 12.8 2.2 0.4 0.5 0.0 2.4 3.7 0.4 4.9 0.4 0.3 1.5 0.1 0.6 2.0 0.4 0.6 7.9 2.1 0.2 0.0 8.5 1.8 1.9 0.4 0.8 3.5 0.2 0.2 0.5 2.8 1.8 7.9 3.8 2.3 5.5 0.0 0.0 1.2 0.8 0.0 0.6 0.3 6.0 2.2 0.4 2.5 0.1 3.7 12.8 1.4 3.2 0.0 0.2 13.4 0.1 3.2 0.9 1.3 0.3 0.4 0.0 4.1 0.0 0.3 0.0 0.0 3.7 0.4 0.3 0.0 11.0 4.1 38.2 8.7 2.3 6.7 53.9 0.0 0.4 0.5 3.3 31.3 5.0 3.7 2.7 25.9 0.5 3.1 1.1 0.0 0.5 14.2 0.1 0.2 0.1 1.0 0.9 0.4 7.8 0.1 0.0 0.0 0.0 4.6 0.0 10.8 0.0 4.0 4.6 0.2 0.1 2.4 5.1 0.0 0.8 0.0 1.2 3.0 1.7 8.0 20.0 20.9 24.3 12.7 0.0 0.5 0.0 0.3 0.0 0.4 1.8 1.4 3.2 0.0 7.5 0.2 5.1 4.0 1.6 1.8 12.1 2.9 2.4 2.2 0.0 0.6 0.0 4.2 0.2 1.9 3.0 0.0 2.9 2.0 1.2 4.8 2.0 0.0 0.4 14.1 4.3 7.6 1.6 0.0 1.6 0.0 0.4 1.1 3.0 1.3 6.7 2.6 2.6 0.0 0.0 0.7 0.5 0.3 1.7 1.8 2.8 0.7 11.3 2.1 2.5 2.4 3.4 0.4 0.0 0.1 3.9 0.6 0.0 0.0 4.9 0.0 0.2 1.0 0.1 1.2 2.0 5.5 0.0 2.5 0.1 2.1 3.5 RTN4RL1 "DKFZp547J144, NgR3, NGRH2" ENSG00000185924 "Reticulon 4 receptor like 1" Q86UN2 17 1934677-2025334 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 20.6;Cone photoreceptor cells: 37.5;Excitatory neurons: 43.5;Horizontal cells: 33.7;Inhibitory neurons: 18.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 12.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 10.9;HaCaT: 10.8;hTCEpi: 10.1;T-47d: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044428 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Midbody" "Intracellular and membrane" Yes NA 35000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "Nucleoplasm, Plasma membrane, Midbody" "HPA044428: AB_10963229" "unprognostic (5.23e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (2.12e-1)" "unprognostic (2.93e-2)" "unprognostic (7.25e-2)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (8.97e-3)" "unprognostic (6.21e-2)" "unprognostic (2.55e-3)" "unprognostic (6.32e-3)" "prognostic unfavorable (7.69e-4)" "unprognostic (3.86e-2)" "unprognostic (1.05e-1)" "unprognostic (7.01e-2)" "unprognostic (3.15e-2)" 4.0 3.1 4.6 0.3 4.0 0.0 6.4 0.0 9.2 2.1 0.0 0.4 0.1 0.8 0.2 1.3 1.5 0.6 2.3 12.3 0.3 1.6 2.6 1.6 0.1 0.0 0.5 0.9 1.8 1.3 5.9 0.3 0.0 3.4 0.1 8.5 4.4 2.0 1.8 9.6 0.5 0.3 0.0 1.1 0.7 0.8 1.9 0.2 1.4 0.4 0.1 1.5 2.2 0.0 1.4 1.6 1.8 2.5 2.0 0.3 0.0 0.1 1.1 0.3 0.0 0.0 0.0 0.0 0.1 10.9 0.2 10.8 4.6 0.1 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 10.1 0.0 3.6 0.0 0.0 2.5 0.1 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.3 0.8 0.3 1.2 0.0 0.0 2.2 0.0 0.3 0.8 1.7 0.2 13.3 0.1 0.0 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.0 0.0 9.2 12.3 0.3 0.0 0.5 0.0 0.0 1.9 0.0 1.0 0.0 2.2 1.6 0.1 2.7 0.2 0.0 1.8 20.6 5.4 4.3 3.0 1.5 1.3 3.7 37.5 0.0 0.1 0.0 0.0 0.6 0.3 0.0 0.0 0.7 0.0 0.0 43.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.1 3.3 1.8 33.7 18.6 0.0 0.0 0.3 0.4 1.1 0.0 0.1 3.6 7.5 0.0 1.8 0.0 8.5 1.7 0.1 0.0 0.0 0.1 0.9 0.0 0.1 1.5 10.0 0.0 0.0 0.6 0.0 0.2 0.5 2.8 0.0 0.2 0.0 0.0 0.3 SCEL "FLJ21667, MGC22531" ENSG00000136155 Sciellin O95171 13 77535674-77645263 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 385.5;skin 1: 302.7" "Cell type enriched" "Detected in many" 12 "Alveolar cells type 1: 679.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 17.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 28.6;HaCaT: 54.6;HBEC3-KT: 25.3;OE19: 74.2;RPTEC TERT1: 107.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA039737, HPA040154" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA039737: AB_10805485, HPA040154: AB_10795359" "unprognostic (1.18e-1)" "unprognostic (1.17e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (4.07e-4)" "unprognostic (5.91e-2)" "unprognostic (4.54e-2)" "unprognostic (6.62e-2)" "unprognostic (3.51e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (1.24e-4)" "unprognostic (4.57e-2)" "prognostic favorable (6.87e-4)" "unprognostic (1.81e-1)" "unprognostic (2.82e-1)" "unprognostic (1.75e-3)" "prognostic unfavorable (1.73e-5)" 3.1 0.1 0.0 0.1 0.1 0.1 19.5 0.1 0.1 69.9 0.0 1.1 0.0 0.1 0.1 385.5 0.3 0.1 0.1 0.0 0.0 0.4 0.1 59.8 0.0 0.1 0.2 0.2 0.2 0.3 0.5 0.8 0.2 0.1 2.0 0.1 57.8 0.0 1.5 302.7 0.1 0.0 0.1 0.0 0.6 2.3 0.1 0.5 2.2 0.0 76.8 0.1 121.6 0.2 16.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.6 0.0 1.8 0.0 0.0 54.6 0.0 25.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 74.2 14.9 0.0 0.0 0.0 107.2 0.0 2.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.2 0.1 679.5 31.6 0.0 0.0 10.7 0.1 12.9 0.0 0.0 0.0 0.0 0.2 0.0 49.7 0.0 0.0 0.3 0.0 0.7 0.0 3.2 6.6 0.7 0.1 0.2 0.0 0.0 0.2 0.2 0.0 2.0 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 7.8 8.2 0.0 1.1 20.9 0.0 0.3 1.8 0.0 0.0 1.6 0.0 1.0 1.7 45.5 0.2 0.0 0.0 0.1 0.0 0.1 7.1 0.0 0.0 0.0 1.2 7.9 5.0 48.8 55.8 0.1 0.3 0.8 0.1 2.7 SCN1A "FEB3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI" ENSG00000144285 "Sodium voltage-gated channel alpha subunit 1" P35498 2 165984641-166149214 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 24.7" "Group enriched" "Detected in some" 11 "Excitatory neurons: 409.9;Inhibitory neurons: 494.6;Oligodendrocyte precursor cells: 692.1" "Cancer enriched" "Detected in single" 8 "glioma: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC TERT1: 6.1;Hep G2: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078664 Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 65: Brain - Ion transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "Nuclear bodies" "HPA078664: AB_2686888" "unprognostic (9.25e-2)" "unprognostic (3.97e-2)" "unprognostic (6.88e-2)" "unprognostic (7.44e-2)" "unprognostic (1.50e-1)" "unprognostic (2.74e-1)" "unprognostic (4.70e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-1)" "unprognostic (9.59e-2)" "unprognostic (1.23e-1)" "unprognostic (5.03e-9)" "unprognostic (6.92e-2)" "unprognostic (3.69e-2)" "unprognostic (5.06e-3)" "unprognostic (6.93e-1)" 0.0 0.0 4.2 0.0 4.2 0.0 0.0 2.1 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.1 6.9 0.0 0.0 1.4 0.0 14.2 6.2 0.0 0.0 0.0 2.0 0.0 18.5 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.1 10.9 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.9 0.0 0.0 6.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 4.2 2.1 24.7 2.1 6.9 14.2 6.2 18.5 2.2 10.9 10.9 0.0 6.4 33.9 27.4 0.0 0.0 0.0 0.0 0.0 47.4 0.6 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.5 0.0 0.3 1.8 0.0 409.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 494.6 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 18.7 0.0 2.8 0.0 692.1 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 SCN5A "CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1" ENSG00000183873 "Sodium voltage-gated channel alpha subunit 5" Q14524 3 38548057-38649687 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Calmodulin-binding, Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Cardiomyopathy, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "heart muscle: 42.8" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 77.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "LHCN-M2: 27.6;RH-30: 22.8" "Group enriched" "Detected in many" 5 "amygdala: 3.1;basal ganglia: 10.1;hypothalamus: 6.0" "Region enhanced" "Detected in many" "basal ganglia: 5.4" HPA063346 Supported "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA063346: " "unprognostic (9.29e-4)" "unprognostic (4.05e-2)" "unprognostic (9.95e-2)" "unprognostic (1.74e-1)" "unprognostic (9.21e-2)" "unprognostic (1.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (8.48e-2)" "unprognostic (7.12e-3)" "unprognostic (5.28e-2)" "unprognostic (1.16e-4)" "unprognostic (4.85e-3)" "unprognostic (1.09e-1)" "unprognostic (5.35e-2)" "unprognostic (4.95e-3)" 0.2 0.1 1.9 0.1 1.2 0.2 0.2 0.0 0.7 1.7 0.0 0.2 0.2 0.7 0.0 0.1 0.3 0.1 42.8 0.2 1.5 0.0 0.0 0.1 0.0 0.0 0.7 0.5 0.0 0.0 0.4 0.2 0.0 0.3 0.1 2.0 0.2 0.5 1.6 0.1 0.2 0.3 0.2 0.1 0.1 0.3 2.6 0.0 0.2 1.0 0.0 0.4 0.7 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.1 0.4 0.1 0.0 0.2 3.6 0.0 0.0 0.0 1.0 0.5 2.7 0.0 0.4 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.4 0.0 2.1 2.8 0.4 0.0 0.0 27.6 1.4 0.0 0.0 2.6 0.0 0.0 0.0 22.8 0.0 0.0 3.2 0.4 3.1 0.0 0.0 0.0 0.8 0.0 0.0 5.7 0.0 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.2 0.0 0.7 0.2 1.5 0.0 0.7 0.0 0.2 2.6 0.2 0.1 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 2.7 0.0 0.3 77.1 0.0 0.1 0.0 14.6 0.2 0.0 0.0 0.0 0.1 1.2 0.1 3.2 2.8 0.0 0.0 0.5 0.0 0.3 3.1 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 6.3 0.3 0.6 0.2 0.0 3.7 0.0 0.6 0.0 1.5 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.9 0.0 7.3 3.1 0.2 1.0 0.0 0.0 0.0 0.1 0.1 0.0 1.4 SCN8A "CerIII, CIAT, MED, NaCh6, Nav1.6, PN4" ENSG00000196876 "Sodium voltage-gated channel alpha subunit 8" Q9UQD0 12 51590266-51812864 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 35.0" "Group enriched" "Detected in many" 8 "Excitatory neurons: 336.7;Inhibitory neurons: 280.1;Oligodendrocyte precursor cells: 104.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 35.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.7;ASC TERT1: 13.5;WM-115: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022169, HPA043937, HPA073590" Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Vesicles, Cell Junctions" "CAB022169: , HPA043937: , HPA073590: " "unprognostic (2.96e-2)" "unprognostic (8.49e-2)" "unprognostic (6.93e-2)" "unprognostic (3.52e-6)" "unprognostic (8.13e-2)" "unprognostic (1.51e-2)" "unprognostic (1.16e-1)" "unprognostic (7.77e-2)" "unprognostic (5.44e-2)" "unprognostic (1.16e-1)" "unprognostic (4.73e-4)" "unprognostic (1.69e-2)" "unprognostic (1.29e-5)" "unprognostic (4.38e-1)" "unprognostic (1.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.75e-2)" 0.2 1.0 5.6 0.4 8.9 0.7 0.5 2.5 35.0 0.4 0.0 0.7 0.2 0.4 0.7 0.1 0.2 0.9 0.1 11.4 0.2 0.9 2.6 0.1 0.4 4.2 0.0 0.5 1.6 0.5 6.7 0.1 3.8 0.6 0.9 7.9 0.6 0.2 0.3 0.3 0.2 0.1 0.0 0.6 1.0 1.7 2.4 0.5 0.5 0.1 0.2 0.2 0.2 11.5 1.7 1.3 13.7 0.2 1.8 13.5 0.3 8.0 12.5 9.1 8.5 2.8 1.6 0.4 1.9 9.9 4.4 0.1 2.3 0.0 10.5 1.6 0.8 0.1 0.3 0.3 0.1 0.2 1.1 1.8 0.0 6.5 1.4 3.4 9.8 3.5 0.2 0.2 5.5 1.0 2.5 0.2 4.9 0.9 4.8 0.1 0.7 0.0 0.0 0.5 5.6 2.2 4.5 2.1 0.3 2.1 0.4 0.2 2.8 8.9 6.3 3.3 5.2 0.2 0.1 0.0 1.8 1.9 13.0 0.5 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.0 0.0 5.6 8.9 2.5 35.0 11.4 0.2 4.2 0.0 3.8 0.0 2.4 11.5 1.2 0.0 0.0 27.1 0.0 0.0 0.5 0.0 3.4 16.7 2.6 1.8 1.4 1.5 0.0 0.0 10.4 0.0 0.3 1.0 0.0 0.5 0.6 0.0 0.7 1.3 11.4 0.0 336.7 0.5 0.0 0.1 3.1 0.0 0.0 0.7 1.1 4.3 0.0 5.0 280.1 1.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 20.6 0.0 4.7 0.0 104.5 14.2 0.7 0.5 0.7 0.0 0.4 0.0 0.7 0.0 11.2 0.0 0.4 0.3 3.8 10.2 0.1 0.0 0.0 0.3 0.0 0.9 0.3 SCNN1D "dNaCh, ENaCdelta" ENSG00000162572 "Sodium channel epithelial 1 subunit delta" P51172 1 1280436-1292029 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.5" "Cell type enhanced" "Detected in many" "Astrocytes: 10.7;Early spermatids: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/70: 9.3" "Low region specificity" "Detected in all" HPA026884 Enhanced Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: Testis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Actin filaments" "HPA026884: AB_10601501" "unprognostic (2.08e-2)" "unprognostic (2.08e-1)" "unprognostic (7.39e-4)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.60e-4)" "unprognostic (1.44e-2)" "unprognostic (1.81e-1)" "unprognostic (2.08e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.32e-4)" "unprognostic (5.27e-2)" "prognostic unfavorable (6.67e-5)" "unprognostic (3.13e-1)" "unprognostic (4.18e-2)" "unprognostic (2.13e-1)" "unprognostic (7.06e-2)" 5.6 7.1 10.3 1.7 10.4 3.2 6.0 11.7 18.1 11.1 5.9 9.4 5.2 8.0 0.9 4.0 14.0 1.2 6.2 9.7 7.5 7.7 13.7 3.7 2.3 10.7 8.5 14.7 4.8 0.7 18.5 1.1 10.9 9.7 0.3 1.7 5.8 1.7 3.4 4.7 7.6 0.8 6.9 8.0 6.3 35.5 9.9 0.9 6.3 1.4 0.7 5.1 7.6 11.7 0.5 4.2 1.6 4.3 1.1 0.6 0.7 2.8 0.8 1.3 1.5 0.8 2.4 3.0 1.5 1.2 2.2 0.7 0.7 0.6 0.2 5.8 2.5 0.4 5.9 1.1 1.1 0.1 2.9 1.8 0.9 2.3 0.0 1.8 0.4 5.5 2.1 7.0 0.3 1.5 1.2 2.0 0.8 0.5 3.0 8.1 0.3 0.7 0.6 0.2 2.2 3.1 1.2 1.2 1.9 0.6 5.4 1.6 1.2 2.6 2.1 4.1 0.9 9.3 0.6 2.5 2.3 5.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 10.4 11.7 18.1 9.7 7.5 10.7 8.5 10.9 6.9 9.9 11.7 1.7 3.2 2.3 10.7 1.0 0.8 0.2 1.2 1.2 3.7 2.2 3.4 4.0 0.0 1.7 0.0 4.2 0.1 0.6 1.0 0.0 0.5 10.5 0.6 2.1 0.6 1.2 2.7 5.2 0.5 0.4 1.7 4.1 1.3 2.5 3.2 0.7 3.5 0.4 5.0 6.0 0.4 0.0 0.8 0.5 4.0 0.9 1.1 0.0 1.0 0.1 1.4 0.0 4.5 5.4 2.0 3.8 1.9 0.7 0.1 3.9 0.7 1.9 2.8 0.0 1.8 1.5 2.8 2.2 0.8 1.6 0.0 1.0 0.5 0.9 0.3 SCNN1G "ENaCgamma, SCNEG" ENSG00000166828 "Sodium channel epithelial 1 subunit gamma" P51170 16 23182745-23216883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.4" "Cell type enriched" "Detected in some" 4 "Collecting duct cells: 90.1" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Region enriched" "Detected in single" 6 "cerebellum: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "hTCEpi: 46.8;RT4: 21.7" "Region enriched" "Detected in single" 13 "cerebellum: 2.5" "Not detected" "Not detected" HPA071194 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA071194: AB_2686359" "unprognostic (2.90e-1)" "unprognostic (5.21e-3)" "unprognostic (5.79e-2)" "unprognostic (4.31e-2)" "unprognostic (1.92e-3)" "unprognostic (1.71e-3)" "unprognostic (1.97e-1)" "unprognostic (4.85e-2)" "unprognostic (7.84e-3)" "unprognostic (1.90e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (3.20e-7)" "unprognostic (2.80e-2)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.17e-3)" 0.7 0.2 0.4 0.0 0.3 0.3 2.3 4.4 0.2 16.0 0.2 10.3 0.0 1.8 0.7 9.9 0.4 0.0 0.0 0.8 0.2 42.4 0.0 7.4 0.0 0.2 0.2 0.0 3.2 0.0 3.8 0.5 0.4 13.8 1.2 0.2 17.7 3.4 0.0 9.7 0.4 0.1 0.0 0.0 10.1 0.1 0.1 2.0 5.7 0.0 1.2 1.4 15.3 0.3 1.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 46.8 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 2.9 0.0 0.0 0.1 0.0 21.7 1.5 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 4.4 0.2 0.8 0.2 0.2 0.2 0.4 0.0 0.1 0.3 0.4 19.2 4.2 0.0 0.0 0.4 4.7 8.8 19.9 0.0 0.8 1.3 0.8 0.0 17.4 90.1 0.0 0.2 0.0 3.4 0.0 2.0 0.0 9.8 1.1 0.1 0.0 0.0 0.2 1.7 0.0 0.4 15.3 18.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 10.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.5 1.1 0.0 0.1 5.3 0.0 0.2 1.9 0.0 0.0 0.0 0.2 0.1 0.1 4.4 0.3 0.1 0.2 0.0 0.4 1.8 SDE2 "C1orf55, FLJ35382" ENSG00000143751 "SDE2 telomere maintenance homolog" Q6IQ49 1 225982702-225999343 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028467, HPA031255, HPA031256" Approved Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "Golgi apparatus, Plasma membrane, Cytosol" "HPA028467: AB_10599192, HPA031255: AB_10601462, HPA031256: AB_10603568" "unprognostic (9.69e-2)" "unprognostic (2.69e-2)" "unprognostic (1.10e-1)" "unprognostic (2.36e-2)" "unprognostic (2.12e-1)" "unprognostic (3.10e-1)" "unprognostic (9.59e-2)" "unprognostic (2.68e-1)" "unprognostic (3.63e-2)" "unprognostic (1.84e-2)" "unprognostic (3.34e-2)" "unprognostic (9.01e-2)" "unprognostic (1.41e-3)" "unprognostic (3.90e-2)" "unprognostic (3.51e-1)" "unprognostic (3.98e-2)" "unprognostic (3.84e-2)" 17.4 8.5 5.5 11.3 7.0 32.9 11.8 6.4 6.6 9.0 4.8 8.3 9.0 11.8 7.8 9.6 7.4 10.5 7.7 4.9 6.0 9.2 14.6 9.2 12.4 6.9 6.6 10.2 9.6 11.1 4.4 11.8 6.6 9.8 9.1 5.1 6.7 7.3 12.7 10.8 9.0 9.8 6.6 10.4 7.7 8.3 6.1 22.8 12.5 9.6 10.6 11.6 7.8 8.4 13.1 9.3 14.9 15.9 10.2 11.3 18.5 13.7 12.9 18.4 14.0 13.7 14.7 19.2 20.9 11.6 7.2 16.5 18.9 11.9 22.2 14.7 15.3 21.1 7.9 12.7 18.6 21.0 24.6 12.5 16.9 19.6 24.6 10.3 12.8 22.6 39.3 22.6 13.7 3.8 29.5 16.6 20.8 20.2 9.8 24.4 19.1 24.9 11.1 9.2 13.3 22.0 15.6 16.9 26.3 11.9 16.6 25.4 12.7 15.6 11.0 20.3 30.4 13.4 10.3 23.4 16.1 12.9 31.5 21.8 6.3 5.9 8.0 6.4 10.8 8.0 8.1 7.8 7.1 7.0 8.1 7.7 18.5 13.5 7.9 8.1 6.7 6.9 5.5 7.0 6.4 6.6 4.9 6.0 6.9 6.6 6.6 6.6 6.1 8.4 36.0 28.9 22.6 4.2 39.9 43.6 17.2 11.2 29.0 6.2 19.8 13.6 9.4 2.8 20.1 9.2 0.0 9.6 29.3 14.3 15.6 6.5 72.8 24.8 15.1 24.8 17.4 56.2 4.7 7.1 10.2 17.8 13.3 35.9 35.5 9.7 12.8 20.6 11.1 15.2 5.0 10.8 16.2 16.4 28.8 20.4 9.9 27.0 19.6 1.9 7.4 12.6 10.3 4.5 8.6 9.7 9.4 6.4 26.6 14.2 9.5 12.7 12.7 8.9 6.6 28.8 23.9 23.9 14.4 26.5 59.1 14.2 23.2 21.0 9.9 18.2 SEMA6C KIAA1869 ENSG00000143434 "Semaphorin 6C" Q9H3T2 1 151131685-151146664 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 322.9;tongue: 96.9" "Cell type enhanced" "Detected in many" "Adipocytes: 12.9;Cardiomyocytes: 19.1;Cone photoreceptor cells: 20.9;Inhibitory neurons: 13.7;Skeletal myocytes: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 14.1;HUVEC TERT2: 24.8;TIME: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA076150, HPA077625" Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 1500000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Plasma membrane" "Nucleoli fibrillar center, Cytosol" "HPA076150: , HPA077625: " "unprognostic (6.97e-2)" "unprognostic (8.40e-2)" "unprognostic (1.56e-3)" "prognostic unfavorable (3.27e-4)" "unprognostic (2.79e-1)" "unprognostic (2.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.24e-2)" "unprognostic (5.66e-3)" "unprognostic (4.25e-2)" "prognostic favorable (3.06e-5)" "unprognostic (3.72e-2)" "unprognostic (1.67e-2)" "unprognostic (6.12e-2)" "unprognostic (9.49e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" 8.8 2.8 7.7 1.8 6.7 1.2 7.9 21.9 9.4 12.0 1.0 7.6 13.7 10.5 1.4 5.5 10.7 3.7 38.8 7.9 5.4 12.1 12.4 5.1 1.7 5.0 5.0 14.8 3.6 2.1 13.4 1.9 4.9 8.3 1.8 5.2 8.5 2.3 322.9 8.9 10.8 6.2 2.2 3.0 5.4 32.2 7.3 2.2 4.7 96.9 0.9 8.4 8.8 5.3 0.9 1.0 14.1 5.4 5.8 1.9 1.3 1.0 0.5 0.9 1.3 0.3 0.6 0.7 4.0 3.3 2.0 1.4 1.3 0.5 0.8 1.3 4.2 7.7 0.7 1.2 0.8 0.1 2.7 3.3 1.7 1.2 0.6 2.8 24.8 4.1 0.7 0.7 2.3 0.5 1.3 1.0 6.3 0.2 1.7 9.0 3.1 0.3 0.5 0.4 7.1 9.3 1.3 0.6 1.2 3.5 1.6 1.3 11.8 2.3 3.3 3.5 0.6 5.9 1.2 6.1 0.6 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 6.7 21.9 9.4 7.9 5.4 5.0 5.0 4.9 2.2 7.3 5.3 12.9 0.0 2.8 3.9 1.0 1.7 0.8 0.3 0.6 5.7 1.9 3.0 19.1 1.5 0.8 0.0 20.9 0.2 0.6 0.1 0.0 0.3 0.6 0.4 2.8 10.2 0.0 0.8 6.7 0.4 0.6 4.4 0.5 0.4 0.0 9.9 6.8 5.3 0.4 6.7 13.7 0.3 0.0 2.5 0.7 3.1 5.6 0.5 1.8 4.7 0.4 1.9 1.0 5.5 1.5 0.4 0.0 2.6 1.9 0.5 3.3 2.9 0.3 7.5 0.0 12.0 2.9 3.3 1.2 0.5 1.0 0.1 0.8 0.5 0.8 0.5 SERINC5 "C5orf12, TPO1" ENSG00000164300 "Serine incorporator 5" Q86VE9 5 80111651-80256048 "Predicted membrane proteins, Transporters" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 223.2;Oligodendrocytes: 222.5;Urothelial cells: 254.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 56.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037898, HPA037899" Supported Supported "Vesicles,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "Vesicles, Centrosome" "HPA037898: AB_10673649, HPA037899: AB_2675727" "unprognostic (2.95e-1)" "unprognostic (1.80e-1)" "unprognostic (4.98e-3)" "unprognostic (1.08e-2)" "unprognostic (5.05e-2)" "unprognostic (1.19e-2)" "unprognostic (1.80e-2)" "unprognostic (8.00e-2)" "unprognostic (2.10e-1)" "unprognostic (2.68e-2)" "unprognostic (7.71e-2)" "unprognostic (1.62e-1)" "unprognostic (1.40e-2)" "unprognostic (4.81e-2)" "unprognostic (8.09e-2)" "unprognostic (4.93e-2)" "unprognostic (9.17e-2)" 12.9 34.8 19.2 9.8 31.0 6.3 11.8 27.2 20.7 16.4 17.4 28.3 9.2 9.2 21.1 17.6 16.2 14.2 5.3 18.0 22.7 6.2 45.4 14.1 8.2 26.5 27.6 15.1 7.6 7.1 4.1 16.5 26.8 33.7 29.4 16.3 13.3 7.0 2.7 19.1 9.7 7.6 22.2 4.8 16.6 29.2 28.0 7.9 5.8 2.9 11.4 17.8 11.3 44.4 11.3 19.7 6.6 4.2 8.9 9.5 19.6 9.0 6.0 3.9 4.0 40.0 56.7 1.7 9.0 11.7 9.2 31.7 8.9 23.9 5.6 1.6 4.8 1.4 2.2 21.7 3.3 1.3 4.1 10.8 13.1 10.2 26.0 11.0 7.3 54.0 3.6 9.4 10.4 19.4 22.8 5.5 9.3 15.8 6.8 26.9 5.8 3.0 11.5 54.4 0.4 6.3 8.0 18.5 35.4 33.5 8.2 6.9 8.0 11.3 3.2 11.6 11.3 7.1 3.5 28.1 21.0 3.9 46.9 10.4 9.1 6.7 2.1 4.9 1.6 0.8 18.7 5.7 5.8 1.1 23.3 14.1 5.2 0.6 1.5 1.4 6.6 7.5 19.2 31.0 27.2 20.7 18.0 22.7 26.5 27.6 26.8 22.2 28.0 44.4 48.5 60.9 30.2 46.0 10.5 6.4 56.8 5.6 19.9 3.6 27.7 14.1 8.2 31.5 18.3 16.5 0.0 16.1 12.9 127.4 9.8 26.5 1.7 82.0 29.6 24.5 60.1 24.8 20.9 19.5 25.7 24.9 40.2 157.0 8.2 27.6 35.3 82.7 21.8 3.3 78.3 60.0 4.1 29.2 27.8 7.6 18.3 38.4 5.4 66.5 44.8 65.1 1.0 223.2 222.5 35.4 56.4 39.9 8.7 148.2 27.7 5.1 4.3 5.3 32.9 7.5 17.4 3.1 12.8 44.4 9.8 129.2 37.7 15.2 85.9 254.2 SHANK1 "SPANK-1, SSTRIP, synamon" ENSG00000161681 "SH3 and multiple ankyrin repeat domains 1" Q9Y566 19 50659255-50719802 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "brain: 71.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.7;Excitatory neurons: 29.6;Horizontal cells: 8.4;Inhibitory neurons: 32.9;Oligodendrocyte precursor cells: 7.1" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.2" "Group enriched" "Detected in many" 5 "amygdala: 20.6;basal ganglia: 28.8;cerebral cortex: 71.1;hippocampal formation: 36.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 5.2;THP-1: 2.4;U-138 MG: 2.7;U-2 OS: 7.3;U-87 MG: 2.9;U-937: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032129, HPA032130" Uncertain Supported "Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA032129: AB_10602796, HPA032130: AB_2674169" "unprognostic (1.62e-1)" "unprognostic (4.40e-2)" "unprognostic (7.83e-3)" "unprognostic (4.62e-2)" "unprognostic (1.70e-2)" "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.35e-2)" "unprognostic (5.02e-2)" "unprognostic (1.61e-1)" "unprognostic (7.51e-2)" "unprognostic (3.27e-1)" "unprognostic (3.65e-2)" "unprognostic (1.61e-2)" "unprognostic (5.14e-2)" "unprognostic (4.66e-3)" "unprognostic (1.29e-3)" 0.0 1.2 20.6 0.0 28.8 0.3 0.1 1.5 71.1 0.5 0.0 0.1 0.0 0.4 0.1 0.0 2.4 0.2 0.1 36.8 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.6 1.1 0.1 0.0 0.1 0.0 5.3 0.1 0.1 0.1 0.3 0.1 0.2 0.0 0.1 0.0 0.5 7.5 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.8 0.0 0.1 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.5 0.1 0.1 0.5 0.8 0.0 0.0 5.2 0.0 0.5 0.0 0.0 0.0 1.8 0.0 0.0 0.8 0.0 0.0 2.4 1.6 2.7 7.3 0.0 0.0 0.0 0.0 0.0 2.9 3.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 28.8 1.5 71.1 36.8 0.0 0.0 0.2 0.0 0.0 7.5 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 4.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.0 29.6 0.0 0.1 0.2 0.0 0.1 0.0 0.5 0.0 0.0 0.0 8.4 32.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.9 0.0 0.1 0.0 7.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SIGLEC10 "MGC126774, PRO940, SIGLEC-10, SLG2" ENSG00000142512 "Sialic acid binding Ig like lectin 10" Q96LC7 19 51410020-51417803 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.5" "Cell type enhanced" "Detected in some" "B-cells: 33.0;granulocytes: 39.3;Kupffer cells: 93.9;Macrophages: 51.5" "Cancer enhanced" "Detected in all" "glioma: 11.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 765.3;intermediate monocyte: 252.0;non-classical monocyte: 539.2" "Group enriched" "Detected in many" 16 "granulocytes: 765.3;monocytes: 539.2" "Cell line enhanced" "Detected in some" "Daudi: 28.8;HDLM-2: 9.0;HEL: 14.9;HMC-1: 10.7;NB-4: 10.4;U-698: 21.3;U-937: 12.0" "Not detected" "Not detected" "CAB025807, HPA027093" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "Plasma membrane, Actin filaments" "CAB025807: , HPA027093: AB_1856858" "unprognostic (7.18e-2)" "unprognostic (3.90e-3)" "unprognostic (1.11e-2)" "unprognostic (3.67e-2)" "unprognostic (3.95e-2)" "unprognostic (9.41e-2)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (3.16e-2)" "unprognostic (1.83e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.73e-1)" "unprognostic (1.69e-2)" "unprognostic (1.39e-1)" "unprognostic (9.05e-2)" 3.5 6.4 3.9 33.9 4.8 14.9 2.1 4.3 6.0 2.1 3.5 5.4 7.0 2.1 1.0 2.0 2.4 3.7 1.4 3.9 6.2 1.7 3.2 8.5 19.9 11.4 6.9 1.6 3.5 1.0 1.4 1.8 8.8 3.0 4.6 1.1 2.2 1.1 0.7 1.2 12.2 4.5 6.3 38.5 4.7 1.3 6.3 4.0 1.0 1.1 19.5 5.5 1.2 9.4 0.2 0.0 0.5 0.5 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 1.3 28.8 0.9 0.1 0.3 0.5 0.0 0.2 0.0 9.0 2.5 14.9 0.3 0.1 0.0 6.4 10.7 0.1 0.0 0.1 0.0 0.1 0.0 1.7 0.7 1.4 0.0 0.6 0.2 10.4 0.8 0.7 0.4 1.9 0.1 0.5 0.0 0.3 0.4 0.4 0.3 0.1 0.2 0.5 0.1 5.2 0.7 0.7 1.3 0.6 0.2 1.3 0.3 21.3 0.5 12.0 0.5 14.0 41.9 765.3 0.8 252.0 0.4 41.4 0.5 0.5 38.0 27.4 0.3 0.5 87.2 0.4 539.2 2.2 1.1 40.7 3.9 4.8 4.3 6.0 3.9 6.2 11.4 6.9 8.8 6.3 6.3 9.4 0.7 3.2 1.3 0.3 33.0 0.1 1.2 0.0 0.0 1.4 0.4 0.9 0.3 0.0 0.0 1.8 2.1 0.1 0.6 0.1 0.0 0.0 0.9 0.0 0.0 4.2 0.0 5.2 0.6 0.0 0.1 0.8 0.0 0.1 39.3 0.1 0.4 1.0 8.1 0.0 0.2 0.1 0.0 93.9 6.3 0.4 0.0 51.5 0.0 15.0 14.8 0.2 6.2 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.1 0.0 0.7 0.0 2.0 0.4 0.5 0.7 0.0 1.3 0.1 2.7 0.1 0.0 0.9 SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51642553-51646801 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.3;lymphoid tissue: 40.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 18.5;Kupffer cells: 41.5;Macrophages: 13.5;monocytes: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 109.1;intermediate monocyte: 125.1;myeloid DC: 65.4;neutrophil: 200.1;non-classical monocyte: 93.3" "Group enriched" "Detected in many" 7 "dendritic cells: 65.4;granulocytes: 200.1;monocytes: 125.1" "Group enriched" "Detected in some" 11 "HMC-1: 98.7;U-937: 24.7" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 24000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane" "HPA014377: AB_2189277, HPA014428: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (6.47e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (9.77e-3)" "unprognostic (9.28e-2)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-3)" "unprognostic (8.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" 3.4 2.4 1.4 25.2 1.5 28.3 1.0 1.6 3.2 1.8 1.3 1.8 0.7 0.9 0.3 1.1 2.3 2.6 1.3 1.4 2.4 0.7 3.5 7.3 13.3 4.7 3.0 0.4 1.1 0.4 0.5 2.5 3.9 0.9 1.6 0.1 1.1 0.9 0.4 0.3 6.1 2.5 2.7 40.3 1.6 2.4 3.9 1.9 0.6 0.0 14.2 4.1 0.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 1.6 98.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 16.6 109.1 1.8 0.3 125.1 0.1 19.3 0.2 0.3 65.4 18.2 0.1 0.1 200.1 0.7 93.3 12.0 0.2 40.3 1.4 1.5 1.6 3.2 1.4 2.4 4.7 3.0 3.9 2.7 3.9 4.1 0.0 0.0 1.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.4 18.5 0.0 0.0 0.0 0.0 41.5 6.0 0.8 0.3 13.5 0.0 1.0 24.1 0.0 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 SIPA1L3 "KIAA0545, SPAR3" ENSG00000105738 "Signal induced proliferation associated 1 like 3" O60292 19 37907208-38208369 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 28.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 93.7;Inhibitory neurons: 87.3;Oligodendrocyte precursor cells: 99.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 59.6" "Low region specificity" "Detected in all" "HPA042072, HPA045480, HPA074988" Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA042072: AB_2677832, HPA045480: AB_2679342, HPA074988: " "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "unprognostic (1.86e-1)" "unprognostic (5.56e-2)" "unprognostic (9.99e-2)" "unprognostic (1.22e-2)" "unprognostic (1.31e-2)" "unprognostic (5.48e-2)" "unprognostic (3.11e-1)" "unprognostic (6.05e-2)" "unprognostic (3.15e-1)" "unprognostic (5.43e-2)" "unprognostic (9.26e-3)" "unprognostic (6.45e-2)" "unprognostic (4.94e-2)" "unprognostic (5.36e-2)" "unprognostic (1.96e-2)" 2.2 3.0 6.0 6.6 3.0 2.9 5.1 10.4 16.2 4.8 2.6 10.6 18.4 3.3 1.3 4.9 4.8 3.9 6.2 28.9 2.0 6.4 3.4 5.7 6.8 4.2 4.1 2.9 9.7 3.3 3.2 1.4 3.5 5.3 7.0 5.0 8.4 3.5 6.5 11.1 18.1 1.8 1.6 7.3 9.1 4.3 5.6 3.8 10.0 7.3 5.5 4.3 3.6 5.5 34.4 59.6 7.3 9.3 4.3 4.3 4.9 14.5 12.2 9.4 8.8 20.6 19.5 19.5 12.2 12.4 7.9 7.6 6.7 27.1 10.4 6.7 3.3 5.3 5.5 6.5 8.3 3.7 5.5 3.3 14.1 17.5 37.3 13.9 10.8 5.6 3.9 4.1 16.6 10.6 5.0 5.1 6.0 27.2 15.8 10.8 5.9 2.9 20.7 29.1 17.3 9.3 16.0 27.1 2.2 3.9 18.0 3.5 23.2 15.6 5.5 48.4 22.6 5.4 10.0 6.6 20.1 4.9 20.6 0.1 0.1 0.4 0.1 0.2 0.0 1.1 0.1 0.2 0.1 1.5 0.1 0.5 0.1 0.3 1.5 0.3 0.1 0.1 6.0 3.0 10.4 16.2 28.9 2.0 4.2 4.1 3.5 1.6 5.6 5.5 4.8 6.4 10.1 41.4 24.5 12.0 5.2 10.4 6.2 21.9 22.6 12.1 5.2 22.8 10.8 23.9 14.6 2.1 9.3 93.7 3.9 7.2 4.5 19.8 4.8 5.4 25.2 10.8 61.1 15.3 1.4 3.7 40.2 16.5 2.5 4.8 6.4 23.5 3.5 33.7 87.3 46.3 20.3 5.1 13.9 9.2 2.1 8.3 5.4 50.6 7.1 3.0 5.2 99.5 58.7 13.4 38.7 1.9 12.8 6.6 50.0 21.1 19.1 5.7 6.6 4.5 3.6 1.7 5.1 8.9 16.1 0.8 5.1 1.7 30.4 5.6 SLC13A3 "NADC3, SDCT2" ENSG00000158296 "Solute carrier family 13 member 3" Q8WWT9 20 46557823-46684467 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "kidney: 407.6" "Cell type enhanced" "Detected in many" "Astrocytes: 53.8;Cytotrophoblasts: 106.6;Excitatory neurons: 65.0;Oligodendrocytes: 178.1;Proximal tubular cells: 245.9;Syncytiotrophoblasts: 79.4" "Cancer enhanced" "Detected in many" "liver cancer: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 16.1;EFO-21: 18.8;Hep G2: 56.1;HHSteC: 18.4;K-562: 15.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014333, HPA014353, HPA014736" Enhanced Supported "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA014333: AB_2732407, HPA014353: AB_1856968, HPA014736: AB_1856970" "unprognostic (1.07e-2)" "unprognostic (7.40e-2)" "unprognostic (5.59e-2)" "unprognostic (1.19e-2)" "unprognostic (3.34e-1)" "unprognostic (3.19e-2)" "unprognostic (2.15e-1)" "unprognostic (2.82e-2)" "unprognostic (1.66e-2)" "unprognostic (9.50e-2)" "unprognostic (1.92e-2)" "unprognostic (1.03e-1)" "unprognostic (8.94e-2)" "unprognostic (3.87e-1)" "unprognostic (1.17e-1)" "unprognostic (1.87e-1)" "unprognostic (2.05e-2)" 1.3 2.4 12.5 0.7 22.8 0.2 1.9 16.5 16.1 2.0 4.9 0.8 0.3 1.8 1.0 0.9 2.4 1.9 1.0 10.1 16.2 407.6 21.7 1.4 0.6 18.3 19.5 4.5 9.0 0.2 2.6 43.2 19.0 6.3 0.5 1.1 4.9 0.8 1.0 2.2 0.4 1.9 12.5 0.6 4.7 8.7 19.9 1.1 1.4 0.3 0.7 1.8 1.4 37.4 0.1 0.0 1.6 5.6 8.3 7.7 16.1 3.5 2.0 1.9 1.4 0.0 0.1 0.2 18.8 0.2 0.1 2.1 0.1 2.6 4.5 0.0 0.6 6.8 0.4 56.1 18.4 0.1 4.8 10.5 7.5 10.9 5.4 5.4 0.0 0.0 15.3 0.3 0.0 0.6 0.1 0.7 10.3 0.2 0.0 0.2 0.0 0.1 1.2 0.4 0.7 0.2 0.0 4.0 0.8 1.0 2.9 0.3 0.2 0.1 4.0 8.7 0.1 0.5 1.2 0.1 0.6 0.0 0.4 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.5 0.0 0.0 12.5 22.8 16.5 16.1 10.1 16.2 18.3 19.5 19.0 12.5 19.9 37.4 0.3 0.0 2.2 53.8 3.8 1.3 1.0 0.8 6.2 0.7 1.2 1.7 1.7 0.0 0.5 7.3 0.0 106.6 0.0 0.1 15.6 0.2 23.3 0.5 2.0 0.6 0.0 0.0 65.0 0.9 7.1 2.3 3.1 0.8 0.0 3.0 0.4 17.5 9.5 0.0 40.3 0.0 0.0 0.3 0.7 27.8 3.1 2.0 0.0 11.2 0.0 0.4 0.0 24.1 178.1 0.9 0.0 0.4 1.2 3.5 0.0 245.9 6.4 0.2 0.0 0.4 1.0 6.6 1.2 1.2 0.6 79.4 1.5 2.2 0.0 0.6 SLC13A5 "INDY, NACT" ENSG00000141485 "Solute carrier family 13 member 5" Q86YT5 17 6684719-6713377 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 414.0" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 381.0" "Cancer enriched" "Detected in some" 15 "liver cancer: 27.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 79 "Hep G2: 58.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044343 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA044343: AB_10961771" "unprognostic (8.46e-3)" "unprognostic (3.89e-2)" "unprognostic (3.24e-2)" "unprognostic (1.75e-2)" "unprognostic (7.33e-2)" "unprognostic (1.07e-1)" "unprognostic (6.79e-2)" "unprognostic (8.79e-3)" "unprognostic (1.32e-1)" "unprognostic (3.23e-1)" "unprognostic (1.26e-3)" "unprognostic (1.30e-3)" "unprognostic (3.78e-11)" "unprognostic (2.42e-2)" "unprognostic (2.46e-1)" "unprognostic (2.05e-2)" "unprognostic (2.04e-1)" 0.3 2.7 4.8 0.0 7.0 0.0 0.3 4.8 8.0 0.3 2.7 0.0 0.0 0.3 0.0 1.1 2.1 0.0 0.1 5.3 7.9 0.7 414.0 0.0 0.2 6.8 6.1 0.6 0.3 0.0 0.8 0.0 5.4 0.0 0.0 1.7 38.0 0.0 0.0 0.1 0.0 0.0 4.8 3.3 0.0 2.3 8.4 0.0 0.0 0.0 0.0 0.0 0.2 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 58.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 7.0 4.8 8.0 5.3 7.9 6.8 6.1 5.4 4.8 8.4 3.9 0.4 0.0 0.0 24.8 4.8 0.5 0.6 0.6 1.2 0.6 0.1 0.1 0.9 7.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.1 1.9 0.0 24.0 0.3 0.5 0.1 0.4 0.0 0.1 0.0 0.9 16.8 381.0 0.0 0.0 0.2 0.0 0.0 23.2 1.1 0.4 0.6 0.3 0.0 1.9 0.0 7.0 0.0 1.5 0.1 16.9 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.6 0.0 0.5 0.5 2.4 2.8 1.2 0.4 0.1 1.0 7.8 0.0 0.3 SLC14A1 "HsT1341, JK, RACH1, RACH2" ENSG00000141469 "Solute carrier family 14 member 1 (Kidd blood group)" Q13336 18 45687025-45752520 "Blood group antigen proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.8;prostate: 78.3;urinary bladder: 90.9" "Group enriched" "Detected in many" 7 "Adipocytes: 136.6;Astrocytes: 228.5;Basal prostatic cells: 313.4;Erythroid cells: 102.5;Prostatic glandular cells: 192.6;Urothelial cells: 249.9" "Group enriched" "Detected in many" 5 "glioma: 5.3;prostate cancer: 8.6;urothelial cancer: 16.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 4.1" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "GAMG: 273.4;RT4: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059570, HPA077233" Approved Supported "Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA059570: AB_2684066, HPA077233: " "unprognostic (2.04e-1)" "unprognostic (2.56e-3)" "unprognostic (5.20e-2)" "unprognostic (1.27e-1)" "unprognostic (6.86e-2)" "unprognostic (1.84e-2)" "unprognostic (1.70e-2)" "unprognostic (7.97e-2)" "unprognostic (8.17e-2)" "unprognostic (9.99e-2)" "unprognostic (2.69e-1)" "unprognostic (1.42e-1)" "unprognostic (3.02e-2)" "unprognostic (2.31e-1)" "unprognostic (1.52e-1)" "unprognostic (9.09e-2)" "unprognostic (6.93e-2)" 3.4 1.6 70.2 1.0 97.1 15.2 2.0 110.5 53.6 3.6 24.9 1.7 1.3 0.5 0.7 0.4 0.3 10.1 23.7 60.5 96.0 37.9 1.1 4.3 2.3 109.4 131.0 0.3 1.7 0.9 1.0 1.6 114.2 78.3 1.3 0.3 2.3 3.0 3.9 4.1 3.4 0.5 97.7 4.6 1.8 0.2 133.8 7.7 6.4 7.8 2.3 90.9 2.2 104.6 0.0 0.4 0.0 0.1 0.0 0.2 0.7 0.4 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 273.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 38.3 0.0 0.2 0.0 0.2 0.3 0.1 0.9 0.3 0.0 0.3 0.2 0.0 0.0 0.2 3.0 113.8 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.8 0.5 0.9 0.1 4.1 0.2 0.1 2.7 1.3 1.3 0.0 0.0 1.1 0.8 0.0 0.0 0.3 0.9 0.9 0.0 0.3 0.2 1.5 0.0 0.9 0.0 0.1 4.1 0.6 70.2 97.1 110.5 53.6 60.5 96.0 109.4 131.0 114.2 97.7 133.8 104.6 136.6 0.0 0.6 228.5 3.1 0.3 313.4 0.1 0.6 0.3 5.4 1.5 10.9 5.7 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.6 0.0 0.1 28.7 0.0 102.5 0.6 0.2 0.1 3.8 0.0 0.1 0.0 0.2 21.4 0.3 0.1 0.0 0.7 0.2 18.3 0.6 0.3 0.4 0.0 2.0 12.4 5.6 0.1 0.0 5.2 3.5 0.7 0.3 0.0 1.2 2.1 192.6 0.0 0.0 0.0 0.2 0.0 1.7 3.7 0.1 0.2 0.2 0.4 0.0 6.1 0.1 0.0 249.9 SLC16A3 "MCT3, MCT4" ENSG00000141526 "Solute carrier family 16 member 3" O15427 17 82217934-82261129 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 198.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1667.1;Syncytiotrophoblasts: 748.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 109.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017490, HPA021451" Approved Supported "Nuclear membrane,Plasma membrane" NA NA 260000 "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "Nuclear membrane" "CAB017490: AB_2189333, HPA021451: AB_1853663" "unprognostic (2.49e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (4.31e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-3)" "unprognostic (4.26e-3)" "prognostic unfavorable (1.19e-7)" "prognostic unfavorable (2.02e-5)" "unprognostic (2.52e-1)" "unprognostic (2.09e-2)" "unprognostic (4.35e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.71e-7)" "unprognostic (2.27e-1)" "unprognostic (4.00e-2)" "unprognostic (8.00e-2)" "unprognostic (1.36e-2)" 30.4 16.9 3.8 25.3 5.8 22.7 15.7 6.6 9.7 26.2 5.0 28.9 11.6 11.6 1.3 42.4 18.5 12.8 26.0 4.5 7.3 48.2 11.3 46.4 5.7 17.3 8.5 9.1 5.8 2.5 12.1 24.7 11.9 19.6 5.7 5.7 27.5 5.9 198.3 8.4 22.9 6.0 8.4 57.5 22.0 32.0 13.8 2.9 29.1 73.2 5.2 26.3 28.5 15.1 52.8 24.4 0.6 1.3 7.8 28.8 51.7 225.6 107.7 117.4 142.2 10.1 119.1 0.7 158.0 122.5 127.9 18.9 15.6 242.0 51.8 78.1 1.2 87.4 144.0 236.4 164.1 105.2 111.5 64.8 38.2 77.0 38.5 185.8 69.1 2.2 1.0 26.6 116.1 14.0 1.4 166.3 1.9 22.1 223.5 0.9 1.6 33.2 75.9 3.0 2.9 1.7 196.7 166.9 3.2 20.4 25.4 131.4 124.0 281.7 5.1 4.5 200.9 97.3 1.9 3.9 140.2 94.7 3.0 56.6 32.6 92.1 9.6 30.4 13.4 8.1 7.7 10.5 24.1 6.2 4.2 5.3 109.1 25.3 31.4 15.2 7.3 16.0 3.8 5.8 6.6 9.7 4.5 7.3 17.3 8.5 11.9 8.4 13.8 15.1 19.2 9.6 9.8 3.6 27.9 6.5 47.5 210.1 2.8 13.4 3.2 2.5 6.1 4.3 182.3 57.0 4.2 67.6 72.4 216.7 0.0 136.1 3.0 33.7 15.4 29.9 20.9 9.1 0.3 18.0 1667.1 17.2 45.3 65.1 75.0 15.9 16.8 1.1 271.0 127.9 0.3 28.3 148.5 99.9 84.6 3.8 3.1 168.6 14.2 9.4 184.9 20.3 40.2 0.0 1.0 305.5 190.2 3.8 35.7 16.5 62.4 5.6 91.1 11.6 0.0 1.6 50.5 1.9 9.5 1.6 6.7 748.8 38.5 0.8 33.4 119.6 SLC16A7 MCT2 ENSG00000118596 "Solute carrier family 16 member 7" O60669 12 59596029-59789855 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 34.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 135.4;Early spermatids: 117.3;Excitatory neurons: 150.5;Inhibitory neurons: 128.2;Late spermatids: 135.5" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 22.2" HPA005911 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Nucleoplasm "HPA005911: AB_1853659" "unprognostic (1.52e-2)" "unprognostic (9.47e-3)" "unprognostic (9.48e-2)" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (1.29e-2)" "unprognostic (5.35e-2)" "unprognostic (8.09e-2)" "unprognostic (1.90e-1)" "unprognostic (1.04e-1)" "unprognostic (8.39e-2)" "unprognostic (9.79e-2)" "prognostic favorable (8.85e-5)" "unprognostic (2.19e-3)" "unprognostic (3.11e-1)" "unprognostic (9.35e-2)" "unprognostic (2.45e-2)" 20.1 6.8 1.2 3.9 1.2 4.7 4.1 5.7 3.9 2.8 3.7 2.0 1.6 3.0 1.5 6.3 2.2 5.4 34.4 1.3 0.3 11.6 3.9 4.5 4.9 2.9 0.4 2.7 9.8 1.0 1.5 1.6 2.9 1.6 2.5 1.8 2.9 1.6 1.8 7.9 2.5 3.5 0.5 6.3 10.0 2.2 1.3 4.5 1.6 3.6 4.2 4.0 3.0 4.2 0.2 3.6 0.8 0.5 10.9 18.1 0.2 8.8 8.1 4.0 3.4 0.3 6.3 5.8 2.5 16.8 3.8 0.8 1.0 1.7 6.0 2.4 0.5 10.7 12.6 0.5 5.9 14.3 0.1 8.5 3.9 1.4 10.3 7.5 1.6 7.2 0.2 13.0 6.5 3.4 5.5 3.2 0.8 1.2 3.3 0.5 0.1 2.7 9.5 16.0 3.0 1.0 0.1 0.4 6.2 0.7 0.5 2.4 0.0 8.6 3.3 15.6 0.5 11.3 0.2 10.0 10.2 0.1 1.6 0.2 1.5 0.0 4.2 3.2 5.6 1.8 3.3 3.6 1.5 4.1 3.5 5.8 0.1 3.0 8.4 2.1 3.8 2.3 1.2 1.2 5.7 3.9 1.3 0.3 2.9 0.4 2.9 0.5 1.3 4.2 15.3 28.9 21.4 13.7 28.4 10.1 7.8 9.9 16.5 24.5 1.5 3.9 135.4 90.1 16.5 46.0 10.4 0.3 29.7 0.8 23.5 53.3 117.3 2.1 25.0 22.0 0.0 2.5 150.5 67.1 0.3 36.2 7.1 9.1 10.1 4.7 9.3 14.5 3.6 8.4 128.2 27.2 6.1 32.7 6.1 135.5 6.8 24.8 3.6 14.0 14.9 1.3 37.0 63.8 82.8 28.0 1.2 10.1 26.3 8.1 1.0 0.7 14.4 6.0 6.6 14.0 18.9 4.2 4.5 61.5 12.6 0.7 35.8 80.1 1.5 3.4 SLC17A5 "AST, ISSD, NSD, SD, SIALIN, SIASD, SLD" ENSG00000119899 "Solute carrier family 17 member 5" Q9NRA2 6 73593379-73653992 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "parathyroid gland: 310.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "thyroid cancer: 47.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 99.9;ASC TERT1: 74.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044479 Supported "Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cytosol" "HPA044479: " "unprognostic (6.48e-3)" "unprognostic (7.95e-3)" "unprognostic (9.23e-2)" "unprognostic (1.45e-2)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (2.59e-3)" "unprognostic (4.44e-2)" "unprognostic (4.18e-2)" "unprognostic (2.60e-1)" "unprognostic (3.14e-2)" "unprognostic (8.29e-2)" "unprognostic (4.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.40e-1)" "prognostic favorable (3.52e-4)" "unprognostic (1.09e-1)" 10.4 10.5 5.9 6.4 6.0 6.8 13.8 6.2 7.0 10.7 5.9 20.4 16.4 9.4 44.6 8.4 5.3 10.4 8.5 6.5 8.5 31.9 17.6 13.2 5.3 6.5 7.0 4.0 11.6 310.5 9.9 21.7 7.8 16.8 22.1 18.3 30.3 14.7 5.4 7.1 21.1 10.6 5.7 7.0 14.4 6.1 7.1 4.5 43.5 6.2 5.6 12.6 6.3 7.6 7.4 9.9 9.7 15.6 99.9 74.2 12.8 23.8 59.4 6.3 22.0 6.6 17.6 6.8 11.2 32.9 14.8 12.6 13.7 5.9 11.2 4.8 15.5 2.8 5.1 15.4 19.4 5.6 10.8 34.2 8.8 14.2 9.7 26.4 16.2 9.0 7.1 7.2 22.3 4.9 2.3 3.3 7.1 30.9 5.7 5.0 12.1 28.5 16.0 20.2 3.8 6.7 4.8 14.0 14.4 14.0 6.3 34.1 23.5 3.0 2.8 12.1 5.7 20.4 30.6 1.9 10.5 11.6 9.0 13.3 7.9 3.3 6.0 7.4 5.8 3.9 6.6 5.8 7.6 2.4 5.4 6.0 5.7 8.9 4.8 5.5 6.6 4.9 5.9 6.0 6.2 7.0 6.5 8.5 6.5 7.0 7.8 5.7 7.1 7.6 8.8 22.4 20.7 16.3 8.2 9.6 13.2 13.7 5.7 8.2 22.6 5.5 6.8 18.6 17.4 51.5 29.2 19.4 11.0 46.4 3.9 14.2 36.6 16.6 7.8 13.8 12.1 3.8 47.7 13.7 13.5 25.8 14.8 19.6 14.5 3.2 23.9 32.9 64.6 0.0 46.8 47.7 20.3 24.8 22.7 48.3 7.5 25.4 10.6 14.0 11.2 8.3 13.4 17.6 16.3 19.2 17.5 11.3 20.6 29.1 23.9 36.3 21.5 28.9 0.0 10.5 9.1 8.4 3.6 10.2 11.2 22.8 11.0 2.9 19.2 30.7 SLC1A6 EAAT4 ENSG00000105143 "Solute carrier family 1 member 6" P48664 19 14950034-15022990 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 88.2;testis: 28.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 17.1;Early spermatids: 35.3;Horizontal cells: 23.5;Late spermatids: 31.8;Syncytiotrophoblasts: 40.0" "Cancer enriched" "Detected in some" 7 "urothelial cancer: 5.2" "Region enriched" "Detected in all" 6 "cerebellum: 88.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 7.4;NTERA-2: 6.1;U-698: 28.3" "Region enriched" "Detected in all" 6 "cerebellum: 136.3" "Region enhanced" "Detected in all" "cerebellum: 53.8" "HPA041505, HPA044066" Enhanced Supported Supported "Plasma membrane,Intermediate filaments" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Intermediate filaments" "HPA041505: AB_2677520, HPA044066: AB_2678796" "unprognostic (3.62e-2)" "unprognostic (1.35e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.94e-3)" "unprognostic (8.90e-2)" "unprognostic (6.52e-4)" "unprognostic (1.55e-1)" "unprognostic (5.40e-3)" "unprognostic (1.11e-2)" "unprognostic (9.92e-2)" "unprognostic (1.35e-1)" "unprognostic (5.57e-2)" "prognostic unfavorable (6.88e-6)" 0.1 0.2 9.1 0.2 10.8 0.9 0.4 88.2 14.4 0.1 0.5 0.2 0.3 0.4 1.7 0.1 0.2 0.2 0.2 14.5 5.0 0.1 0.2 0.2 0.3 3.7 7.5 0.3 0.6 0.9 0.3 0.7 8.1 0.5 0.3 2.3 0.4 0.5 0.3 8.6 0.3 0.2 3.2 0.4 0.2 28.0 6.6 0.2 0.3 0.1 0.3 0.1 0.1 5.1 0.1 0.1 0.3 0.4 0.2 0.2 0.9 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 1.4 7.4 0.2 0.1 0.2 0.1 0.2 0.4 0.3 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.6 0.1 0.6 0.0 0.5 6.1 0.0 0.1 0.1 0.1 0.1 0.1 0.3 0.5 0.2 0.2 2.8 0.0 1.1 0.3 0.1 0.0 0.3 1.1 0.3 0.1 0.5 0.1 28.3 0.1 0.3 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 9.1 10.8 88.2 14.4 14.5 5.0 3.7 7.5 8.1 3.2 6.6 5.1 0.0 0.0 0.0 0.7 0.0 3.2 0.7 0.0 0.0 17.1 0.0 0.1 2.1 0.0 0.0 1.8 0.0 1.9 0.0 0.0 0.0 0.0 35.3 0.0 0.1 0.1 0.0 0.0 8.2 0.4 9.9 0.4 0.0 0.0 0.0 5.8 0.0 0.0 0.5 23.5 8.6 0.0 0.0 0.0 0.7 31.8 0.6 0.0 0.0 1.0 0.0 0.7 0.0 4.5 0.9 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.0 0.8 0.0 0.0 0.4 2.2 6.3 0.0 6.8 40.0 0.0 0.0 0.0 0.1 SLC24A2 NCKX2 ENSG00000155886 "Solute carrier family 24 member 2" Q9UI40 9 19507452-19786928 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sensory transduction, Sodium transport, Symport, Transport, Vision" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 117.1" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 2710.1" "Group enriched" "Detected in some" 4 "breast cancer: 0.5;glioma: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 2.6;SCLC-21H: 2.2;U-87 MG: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079359 Supported "Plasma membrane" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA079359: " "unprognostic (1.30e-1)" "unprognostic (8.57e-2)" "unprognostic (4.20e-1)" "unprognostic (1.05e-2)" "unprognostic (3.33e-2)" "unprognostic (1.48e-2)" "unprognostic (8.46e-2)" "unprognostic (8.37e-2)" "unprognostic (1.27e-1)" "unprognostic (1.50e-2)" "unprognostic (6.51e-2)" "unprognostic (1.57e-2)" "unprognostic (2.08e-4)" "unprognostic (1.58e-1)" "unprognostic (2.11e-3)" "unprognostic (1.51e-2)" 0.1 5.9 28.4 0.0 64.7 0.1 0.0 42.3 64.6 0.1 0.0 0.1 0.0 2.0 0.0 0.0 0.5 0.1 0.0 19.2 19.1 0.1 0.0 0.0 0.0 81.3 36.3 0.0 0.0 0.0 0.8 0.1 87.7 0.1 0.0 18.7 0.0 0.0 0.1 0.1 0.0 0.0 19.4 0.1 0.1 0.2 81.9 0.0 0.0 0.3 0.0 0.0 0.0 117.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.1 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.2 0.1 0.1 0.0 28.4 64.7 42.3 64.6 19.2 19.1 81.3 36.3 87.7 19.4 81.9 117.1 0.0 0.0 0.0 18.9 0.1 0.0 0.0 0.0 0.0 58.7 0.0 0.0 2.3 0.0 0.0 0.0 273.1 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.0 668.6 0.0 0.1 0.9 0.0 0.1 0.0 0.0 1.4 0.0 0.1 97.6 637.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 25.3 0.0 4.1 0.0 217.6 2710.1 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 10.4 0.0 3.2 0.2 0.2 0.7 0.0 0.1 0.3 0.0 0.0 0.1 0.0 SLC28A1 CNT1 ENSG00000156222 "Solute carrier family 28 member 1" O00337 15 84884654-84945798 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 49.1;kidney: 48.2;liver: 111.3" "Group enriched" "Detected in some" 5 "Hepatocytes: 38.6;Hofbauer cells: 54.3;Proximal enterocytes: 86.9;Proximal tubular cells: 93.4" "Group enriched" "Detected in some" 63 "liver cancer: 10.9;renal cancer: 33.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA019551, HPA056247" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Nuclear speckles, Cytosol" "HPA019551: AB_2670187, HPA056247: " "unprognostic (3.81e-2)" "unprognostic (1.60e-1)" "unprognostic (2.22e-1)" "unprognostic (7.49e-2)" "unprognostic (5.08e-2)" "unprognostic (7.08e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (1.98e-1)" "unprognostic (2.18e-2)" "unprognostic (1.63e-1)" "unprognostic (8.37e-2)" "unprognostic (1.35e-1)" "unprognostic (7.42e-2)" "unprognostic (7.72e-3)" "unprognostic (6.65e-2)" "unprognostic (1.55e-1)" 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.1 0.3 0.0 0.0 37.9 0.0 0.5 0.1 0.7 0.2 1.0 0.1 0.3 48.2 111.3 0.0 0.2 0.9 0.3 0.0 0.0 0.2 0.2 1.2 0.7 0.0 0.0 0.0 0.1 0.0 1.5 0.0 49.1 0.0 0.4 0.0 0.1 0.1 0.2 0.0 0.0 3.3 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.3 0.9 0.3 0.7 0.4 0.2 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.3 2.2 4.3 0.6 7.3 0.0 0.5 0.0 0.0 11.7 3.0 0.0 0.4 0.1 0.1 0.0 0.0 0.5 0.0 0.5 0.4 0.0 0.6 0.0 0.0 0.4 38.6 54.3 0.0 0.5 2.8 0.0 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.5 1.1 0.3 2.5 0.0 0.0 0.0 86.9 93.4 1.4 0.0 0.0 2.6 0.2 0.0 0.0 0.0 0.0 0.8 0.4 0.3 1.5 0.1 SLC2A2 GLUT2 ENSG00000163581 "Solute carrier family 2 member 2" P11168 3 170996347-171026743 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 836.1" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 457.6" "Cancer enriched" "Detected in some" 12 "liver cancer: 105.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 55 "CACO-2: 7.7;Hep G2: 27.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010444, HPA028997" Enhanced Supported "Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "CAB010444: AB_641068, HPA028997: AB_2672860" "unprognostic (9.56e-2)" "unprognostic (1.24e-1)" "prognostic favorable (2.63e-5)" "unprognostic (3.10e-1)" "unprognostic (1.02e-1)" "unprognostic (2.95e-2)" "unprognostic (6.31e-2)" 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.2 0.4 0.0 0.2 0.0 66.1 0.0 0.0 0.0 0.0 5.2 0.0 0.3 0.3 30.8 836.1 0.0 0.0 0.5 0.4 0.0 2.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 27.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.2 0.4 0.3 0.3 0.5 0.4 0.8 0.4 0.4 2.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 90.1 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.2 6.7 0.0 0.0 0.1 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 457.6 0.0 0.0 0.1 3.0 0.0 10.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 2.5 0.0 0.0 0.0 105.4 63.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 1.8 0.0 SLC30A1 "ZNT1, ZRC1" ENSG00000170385 "Solute carrier family 30 member 1" Q9Y6M5 1 211571568-211579161 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 86.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 94.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015275, HPA049000" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "HPA015275: AB_1857083, HPA049000: AB_2680593" "unprognostic (1.13e-1)" "unprognostic (2.67e-3)" "unprognostic (6.94e-2)" "unprognostic (1.81e-3)" "unprognostic (3.47e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-2)" "unprognostic (1.82e-3)" "unprognostic (4.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.42e-3)" "unprognostic (4.78e-2)" "unprognostic (2.23e-2)" "unprognostic (3.03e-1)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (4.53e-2)" 14.8 18.0 15.7 10.9 17.0 29.8 8.5 15.2 19.3 18.6 27.8 15.4 28.2 10.8 9.9 8.0 12.5 12.4 10.0 16.9 15.4 20.5 86.1 7.2 6.1 17.9 17.3 7.8 11.3 10.3 4.6 10.1 16.8 7.8 13.6 6.1 9.3 7.9 1.8 16.0 19.9 11.6 16.7 15.4 9.5 13.4 18.9 4.5 16.9 4.8 7.1 12.2 7.5 13.2 10.3 15.0 7.7 9.9 32.4 14.9 70.5 27.3 19.3 13.8 13.6 6.4 46.6 5.8 24.1 24.4 19.3 17.2 11.5 15.4 16.4 15.0 9.3 4.7 28.8 14.7 18.1 15.8 10.0 22.5 37.5 17.7 28.4 20.5 8.6 3.4 18.7 25.5 17.2 9.1 3.2 9.9 24.2 10.6 12.0 10.0 3.7 20.4 42.5 26.4 7.8 13.7 26.7 13.6 62.7 14.2 7.0 20.2 14.6 10.4 24.8 35.4 22.1 11.9 19.0 4.5 9.8 15.7 9.3 1.4 1.3 0.5 0.4 1.5 0.5 0.2 0.3 0.2 0.9 0.1 0.3 0.4 0.1 0.4 1.2 0.5 0.3 0.4 15.7 17.0 15.2 19.3 16.9 15.4 17.9 17.3 16.8 16.7 18.9 13.2 29.7 9.6 9.8 3.9 8.8 28.6 8.2 3.0 16.5 11.0 24.9 14.7 21.0 18.6 4.2 36.8 6.2 11.6 19.9 54.5 1.9 6.9 44.0 37.0 19.1 27.3 9.5 26.1 0.6 12.5 32.7 15.9 8.6 66.4 5.1 7.5 17.9 94.9 32.0 6.7 0.6 22.8 2.0 27.2 14.5 6.8 9.9 25.5 21.4 3.7 18.8 29.0 1.0 1.0 0.1 9.5 41.7 7.5 8.6 13.9 49.2 29.8 6.4 9.4 6.6 15.9 11.7 37.9 17.4 24.2 46.2 24.5 14.2 14.8 23.3 13.7 SLC34A1 "NAPI-3, NPT2, NPTIIa, SLC11, SLC17A2" ENSG00000131183 "Solute carrier family 34 member 1" Q06495 5 177379235-177398848 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "kidney: 155.4" "Cell type enriched" "Detected in some" 14 "Proximal tubular cells: 143.2" "Cancer enriched" "Detected in single" 12 "renal cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HEL: 2.4;U-937: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051255, HPA077175" Approved Approved "Nucleoplasm,Nuclear speckles,Plasma membrane,Mitotic spindle,Cytosol" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Plasma membrane" "Nucleoplasm, Mitotic spindle, Cytosol" "HPA051255: AB_2681409, HPA077175: " "unprognostic (1.17e-1)" "unprognostic (3.33e-3)" "unprognostic (1.49e-1)" "unprognostic (3.49e-2)" "unprognostic (1.56e-3)" "unprognostic (2.28e-1)" "unprognostic (4.50e-2)" "unprognostic (4.43e-3)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" "unprognostic (5.95e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (2.01e-1)" "unprognostic (1.28e-2)" "unprognostic (4.66e-2)" 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 155.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 7.3 0.0 0.0 0.2 0.0 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 143.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.1 SLC34A2 NAPI-3B ENSG00000157765 "Solute carrier family 34 member 2" O95436 4 25648011-25678748 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lung: 753.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 477.5;Alveolar cells type 2: 1315.9;Club cells: 179.9;Glandular and luminal cells: 241.3;Respiratory ciliated cells: 217.0" "Group enriched" "Detected in many" 4 "lung cancer: 252.6;ovarian cancer: 191.7;thyroid cancer: 585.2" "Region enriched" "Detected in single" 6 "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 82 "BEWO: 32.2;EFO-21: 121.0;RPTEC TERT1: 86.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037989, HPA066474" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Lung - Lung function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA037989: AB_10670536, HPA066474: " "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "unprognostic (1.38e-1)" "unprognostic (4.25e-2)" "unprognostic (7.33e-2)" "unprognostic (9.83e-2)" "unprognostic (2.37e-2)" "unprognostic (6.60e-3)" "unprognostic (6.27e-2)" "unprognostic (1.89e-2)" "unprognostic (5.77e-2)" "unprognostic (2.24e-1)" "unprognostic (7.08e-3)" "unprognostic (3.25e-1)" "unprognostic (6.75e-2)" "unprognostic (2.57e-2)" "unprognostic (1.93e-1)" 0.4 0.8 0.0 0.3 0.0 0.0 19.1 2.1 0.2 66.6 6.9 0.1 16.4 34.6 0.1 1.5 69.8 9.0 0.2 0.1 0.0 16.7 1.2 753.0 0.1 0.0 0.0 1.3 7.3 0.0 2.1 4.8 0.1 1.0 0.0 0.5 90.2 16.8 0.1 2.6 4.3 0.2 0.0 0.7 2.5 2.7 0.3 2.1 33.6 0.0 7.4 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 32.2 0.0 0.0 0.0 0.0 0.2 0.1 0.2 121.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.4 0.1 0.0 0.2 0.1 0.1 86.8 0.0 0.1 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.5 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 477.5 1315.9 0.0 0.1 0.0 0.1 79.1 0.0 0.0 41.5 7.5 0.8 34.3 179.9 20.2 0.0 1.4 0.0 0.0 5.9 72.2 5.4 78.6 30.3 2.5 0.0 0.0 0.1 8.5 0.0 2.6 0.0 241.3 29.0 0.0 0.0 0.0 0.2 0.0 0.1 1.2 26.4 0.0 0.0 20.8 1.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 2.5 0.0 0.0 11.8 13.6 3.4 217.0 0.0 0.0 0.0 5.8 2.1 0.1 0.0 0.0 0.3 4.8 0.0 1.8 4.0 SLC35G2 "DKFZp564K2464, MGC3295, TMEM22" ENSG00000168917 "Solute carrier family 35 member G2" Q8TBE7 3 136818647-136855888 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 54.2;Early spermatids: 65.4;Inhibitory neurons: 42.4;Spermatocytes: 35.5" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 10 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 73.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052054, HPA064728" Approved Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA052054: AB_2681709, HPA064728: AB_2685336" "unprognostic (1.04e-1)" "unprognostic (1.46e-2)" "unprognostic (6.91e-4)" "unprognostic (2.56e-4)" "unprognostic (5.34e-2)" "unprognostic (6.73e-2)" "unprognostic (1.16e-5)" "unprognostic (1.83e-3)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (1.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" "unprognostic (1.07e-2)" "unprognostic (2.30e-2)" 14.9 15.4 20.9 2.1 21.2 0.5 11.1 23.1 26.4 5.1 16.5 3.8 1.0 4.3 4.6 2.6 5.7 5.3 8.1 20.0 24.4 3.9 4.4 7.0 1.9 21.4 25.0 5.5 7.6 6.7 19.3 7.4 26.9 4.1 2.0 5.3 3.1 2.6 2.4 3.7 2.9 5.1 22.1 3.2 2.9 14.4 22.6 2.8 8.5 5.4 1.2 6.5 5.0 21.0 3.9 10.7 10.6 4.8 20.8 17.1 0.0 16.9 73.1 24.7 37.0 10.1 5.7 0.0 12.7 17.5 39.3 1.3 12.7 0.7 22.8 0.1 3.5 3.2 12.0 6.3 26.6 0.1 0.0 24.2 1.8 21.5 5.9 18.0 18.8 6.8 1.8 0.1 32.1 0.0 4.7 3.3 2.3 0.0 7.9 4.2 7.1 0.2 21.1 0.9 17.5 11.7 13.7 0.0 24.0 3.6 0.0 1.8 13.1 18.4 4.7 8.2 18.6 0.0 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 20.9 21.2 23.1 26.4 20.0 24.4 21.4 25.0 26.9 22.1 22.6 21.0 22.4 12.8 7.0 54.2 2.5 3.3 4.9 12.0 7.4 4.7 0.7 0.8 2.5 1.5 7.1 1.8 12.5 1.3 2.7 0.8 1.9 3.3 65.4 1.0 1.6 30.6 4.2 4.4 34.0 10.7 1.3 12.4 0.5 1.3 2.5 3.6 27.8 2.3 0.7 6.7 42.4 1.0 0.0 2.2 7.3 30.3 9.9 2.1 3.6 17.8 3.7 7.8 15.5 15.6 6.1 10.0 0.1 3.0 3.7 4.7 0.6 0.7 1.4 4.6 6.6 4.7 4.8 35.5 16.1 1.2 3.0 2.2 3.8 3.1 0.6 2.0 SLC38A2 "ATA2, KIAA1382, SAT2, SNAT2" ENSG00000134294 "Solute carrier family 38 member 2" Q96QD8 12 46358188-46372773 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 1118.3;Suprabasal keratinocytes: 1078.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 1198.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035180, HPA069672" Approved Supported "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "HPA035180: AB_10669901, HPA069672: " "unprognostic (6.61e-3)" "unprognostic (2.87e-2)" "unprognostic (4.88e-2)" "unprognostic (2.51e-2)" "unprognostic (2.96e-1)" "unprognostic (1.00e-2)" "unprognostic (7.78e-2)" "unprognostic (5.50e-3)" "unprognostic (1.20e-1)" "unprognostic (3.79e-1)" "unprognostic (9.24e-3)" "unprognostic (1.75e-1)" "unprognostic (1.47e-1)" "unprognostic (5.08e-2)" "unprognostic (3.80e-1)" "unprognostic (1.83e-1)" "unprognostic (8.68e-2)" 112.8 113.0 36.1 71.6 48.5 95.4 88.5 53.9 50.2 91.7 25.8 58.3 33.6 92.9 38.6 108.1 83.6 131.3 60.7 32.4 46.1 64.8 307.3 117.0 67.1 52.2 42.7 130.1 74.7 91.5 27.9 162.1 53.5 52.8 49.7 27.0 77.2 43.1 108.5 204.4 54.4 115.8 44.2 75.3 63.0 25.4 44.2 100.4 63.1 174.7 78.1 98.9 88.0 73.0 83.7 179.9 157.6 444.1 356.7 347.7 118.1 382.8 921.2 313.0 254.0 108.2 151.2 0.1 504.2 627.9 215.3 271.1 107.9 335.1 299.1 67.0 61.0 105.8 208.7 339.9 548.8 88.0 108.7 357.2 718.4 199.5 1198.9 778.5 265.7 116.3 103.8 163.1 560.4 100.0 110.3 122.8 138.2 0.1 185.1 97.5 115.5 200.9 191.6 173.4 103.9 89.8 263.5 68.5 233.7 171.0 140.5 193.8 467.3 156.7 121.8 67.8 62.2 187.8 194.3 100.6 148.0 304.5 76.8 41.1 24.9 18.9 22.7 13.1 17.4 19.2 19.0 23.0 35.2 17.8 23.5 24.8 17.5 51.6 18.4 40.6 23.7 27.6 36.1 48.5 53.9 50.2 32.4 46.1 52.2 42.7 53.5 44.2 44.2 73.0 237.7 83.3 77.4 31.3 187.7 1118.3 134.1 262.8 653.9 40.5 315.7 252.2 153.6 108.7 123.9 57.0 70.9 53.8 292.3 114.6 5.9 41.2 5.5 228.5 245.0 234.7 76.7 109.0 54.6 51.1 49.3 219.1 328.2 464.0 81.6 138.3 227.7 265.9 54.0 53.8 58.9 175.0 130.2 143.3 303.6 12.4 263.2 193.8 250.8 59.0 52.6 74.3 70.0 42.3 136.2 79.4 83.5 85.0 322.2 181.7 67.4 24.4 50.3 68.7 282.7 184.8 339.5 6.7 15.5 532.6 1078.3 38.4 252.4 84.0 110.7 150.8 SLC39A6 LIV-1 ENSG00000141424 "Solute carrier family 39 member 6" Q13433 18 36108531-36129385 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast glandular cells: 307.0;Prostatic glandular cells: 197.9" "Group enriched" "Detected in all" 4 "breast cancer: 361.9;prostate cancer: 127.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042377 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 35: Glandular cells - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA042377: AB_2677968" "unprognostic (7.60e-2)" "unprognostic (2.27e-2)" "unprognostic (5.50e-3)" "unprognostic (2.58e-3)" "unprognostic (1.02e-1)" "unprognostic (4.87e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (1.18e-1)" "unprognostic (3.19e-1)" "unprognostic (4.50e-2)" "unprognostic (7.63e-3)" "unprognostic (2.16e-1)" "unprognostic (4.74e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" 27.3 25.9 23.3 21.6 28.5 11.6 147.2 28.6 26.1 34.5 48.9 13.9 9.6 56.9 56.2 17.0 63.6 24.2 14.0 20.0 28.8 28.2 16.5 18.9 17.3 28.8 33.6 43.1 37.7 86.5 23.9 31.7 30.6 129.0 13.4 50.2 30.9 114.3 12.7 51.3 8.9 30.2 28.6 15.5 16.4 19.3 26.7 18.5 37.3 16.6 28.4 52.6 16.1 34.2 43.7 54.0 127.1 75.1 131.4 96.6 33.0 116.2 137.3 76.5 88.7 30.3 47.5 47.1 57.3 113.1 53.1 104.1 112.4 109.2 115.5 105.4 40.7 20.6 69.5 44.4 83.2 69.8 49.6 88.7 236.1 116.2 100.5 69.9 11.7 38.6 10.7 92.1 108.9 67.0 69.0 15.6 30.6 24.0 30.4 70.6 72.8 61.4 84.4 145.2 132.8 116.8 143.5 41.5 200.6 52.1 56.7 32.4 18.9 184.9 30.5 35.5 59.2 85.9 90.0 35.7 64.0 48.3 99.8 29.2 13.3 31.2 16.3 19.7 19.7 16.7 13.8 14.7 16.4 17.3 12.0 17.7 10.2 18.1 19.4 33.6 17.0 14.2 23.3 28.5 28.6 26.1 20.0 28.8 28.8 33.6 30.6 28.6 26.7 34.2 13.3 38.5 18.7 8.8 22.5 45.9 58.2 79.6 59.2 41.5 307.0 132.2 19.6 10.0 66.4 42.3 33.3 6.6 36.7 4.0 1.9 53.1 21.3 37.1 76.1 12.9 25.6 4.6 13.0 37.8 56.7 45.6 9.2 73.8 23.5 18.9 8.9 11.0 20.4 23.5 23.9 7.4 38.7 20.1 30.0 18.1 37.3 26.0 67.6 1.9 25.7 38.2 10.3 34.2 36.5 39.5 1.9 47.8 24.4 197.9 2.7 13.6 44.3 41.3 39.5 40.4 38.6 43.9 27.8 32.6 74.4 23.8 23.2 23.0 5.7 69.3 SLC3A2 "4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE" ENSG00000168003 "Solute carrier family 3 member 2" P08195 11 62856004-62888880 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 780.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 1441.0;SiHa: 1287.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010455, HPA017980" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 170000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Plasma membrane" "CAB010455: AB_638288, HPA017980: AB_2669723" "unprognostic (1.79e-1)" "unprognostic (9.61e-3)" "unprognostic (3.59e-1)" "unprognostic (7.87e-3)" "unprognostic (2.06e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (2.09e-3)" "unprognostic (2.62e-1)" "unprognostic (4.16e-2)" "unprognostic (2.29e-2)" "unprognostic (3.71e-1)" "prognostic favorable (8.22e-4)" "unprognostic (2.92e-2)" "unprognostic (5.52e-3)" "unprognostic (3.49e-3)" "prognostic unfavorable (1.48e-4)" 103.3 105.6 130.5 46.7 138.0 122.0 108.9 140.1 160.4 101.6 115.6 60.6 51.5 97.2 65.3 112.9 94.0 35.8 52.0 123.1 133.3 171.2 71.9 117.8 34.9 138.4 132.6 93.0 109.7 189.7 65.3 55.4 134.0 100.8 23.1 22.8 110.6 41.9 122.3 127.1 79.7 33.8 135.8 77.4 90.2 65.1 154.5 30.1 110.2 26.0 28.8 77.7 95.1 130.6 155.5 675.7 60.2 213.2 89.7 69.7 596.7 267.5 106.2 154.0 126.3 643.3 293.0 173.9 290.5 185.4 284.5 540.0 123.1 588.9 84.3 319.3 114.0 117.5 422.4 299.2 825.7 136.0 169.4 144.9 1441.0 175.3 528.8 46.2 83.6 380.7 232.9 347.4 95.1 792.6 149.8 181.3 106.9 222.5 214.2 153.8 92.7 341.8 113.9 84.0 112.5 53.5 1287.0 499.6 948.5 121.2 161.5 182.6 146.2 138.3 200.0 204.4 195.5 436.0 556.1 561.2 135.0 225.1 418.0 37.8 149.0 49.7 117.9 147.4 157.7 58.3 107.3 122.1 88.6 72.1 90.1 97.2 31.2 90.3 123.9 304.7 112.5 186.3 130.5 138.0 140.1 160.4 123.1 133.3 138.4 132.6 134.0 135.8 154.5 130.6 97.8 48.1 37.3 91.1 78.8 218.1 244.2 321.7 399.5 58.4 124.2 120.8 13.4 30.0 141.1 49.7 66.7 222.5 136.2 109.6 33.2 161.9 31.5 122.0 96.3 149.2 84.3 117.7 16.9 151.1 143.7 102.9 71.4 179.7 84.3 43.2 99.2 27.0 202.9 53.8 25.1 60.4 223.8 54.1 140.9 28.9 30.4 141.5 224.1 29.0 104.7 188.4 40.2 21.1 11.3 130.6 58.7 30.5 140.9 156.9 120.7 227.4 63.4 61.2 6.6 71.8 114.6 21.3 31.9 160.7 150.6 780.7 118.1 52.4 60.7 194.9 SLC40A1 "FPN1, HFE4, IREG1, MTP1, SLC11A3" ENSG00000138449 "Solute carrier family 40 member 1" Q9NP59 2 189560590-189583758 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 489.8;Kupffer cells: 1340.2;Syncytiotrophoblasts: 2463.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 326.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 509.0;CACO-2: 123.1;HEL: 430.0;HMC-1: 110.5;T-47d: 207.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065634 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA065634: AB_2685524" "unprognostic (1.28e-2)" "unprognostic (1.73e-2)" "unprognostic (9.41e-2)" "unprognostic (1.83e-2)" "unprognostic (8.00e-3)" "unprognostic (1.36e-2)" "unprognostic (1.66e-1)" "unprognostic (6.22e-2)" "unprognostic (6.65e-2)" "unprognostic (1.84e-1)" "unprognostic (6.43e-2)" "unprognostic (6.44e-2)" "prognostic favorable (8.55e-5)" "unprognostic (4.66e-1)" "unprognostic (1.61e-1)" "unprognostic (8.96e-2)" "unprognostic (4.11e-2)" 59.6 333.5 9.3 52.6 11.9 45.8 97.7 9.6 9.8 156.3 10.4 124.7 289.3 95.4 61.6 30.5 214.2 148.7 52.6 7.2 12.0 79.9 251.5 122.9 172.6 15.6 15.7 317.2 53.2 91.8 19.0 250.1 12.8 39.5 130.8 29.5 58.7 53.1 64.2 12.2 127.9 69.3 15.5 368.1 96.8 33.2 13.9 62.6 68.0 60.3 59.1 53.1 21.8 11.3 0.0 7.4 0.6 0.0 509.0 3.3 25.4 0.2 6.6 1.9 3.1 123.1 0.4 0.2 1.0 0.2 1.4 0.4 2.4 0.3 1.6 0.3 1.7 430.0 1.7 45.8 1.9 1.5 110.5 35.9 0.2 1.2 0.0 11.7 13.0 16.4 44.6 1.1 6.3 0.0 18.2 28.8 1.5 92.7 1.7 0.2 5.0 2.5 5.3 18.1 1.0 5.4 0.8 35.4 0.0 39.5 207.6 6.2 0.3 0.8 11.7 0.5 0.1 1.1 0.2 0.3 0.1 0.2 0.1 129.8 101.5 172.1 2.2 23.7 3.2 0.2 54.4 4.9 115.6 0.7 80.2 17.8 326.2 4.6 2.6 18.8 5.3 105.8 9.3 11.9 9.6 9.8 7.2 12.0 15.6 15.7 12.8 15.5 13.9 11.3 44.2 125.0 40.3 3.6 12.0 9.2 51.3 10.5 19.9 4.8 83.8 30.0 48.0 138.7 31.6 33.1 4.2 489.8 5.7 328.9 49.0 54.7 10.5 39.6 38.2 39.8 18.6 253.7 0.3 71.8 20.3 81.9 76.5 129.5 9.5 12.8 245.9 259.7 86.4 6.7 6.8 60.8 6.1 1340.2 26.8 9.2 121.2 172.7 8.8 34.7 41.7 17.5 2.1 14.6 0.2 71.5 86.2 58.6 4.1 26.2 163.0 150.0 34.4 48.4 65.7 13.7 49.1 7.4 3.9 12.5 8.1 2463.5 11.9 84.8 48.9 27.7 SLC41A3 FLJ20473 ENSG00000114544 "Solute carrier family 41 member 3" Q96GZ6 3 126006357-126101561 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045847 Approved Supported "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA045847: AB_2679472" "unprognostic (1.77e-1)" "unprognostic (3.35e-2)" "unprognostic (1.11e-1)" "unprognostic (3.37e-2)" "unprognostic (7.68e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (1.36e-1)" "unprognostic (3.23e-2)" "unprognostic (2.82e-3)" "unprognostic (5.74e-2)" "unprognostic (3.57e-1)" "prognostic favorable (6.04e-7)" "unprognostic (1.26e-1)" "unprognostic (5.88e-2)" "unprognostic (2.85e-1)" "unprognostic (7.54e-2)" 29.5 47.2 53.3 13.3 55.6 11.3 29.5 55.0 56.1 42.4 53.0 24.8 18.1 44.4 55.1 22.2 40.2 28.6 34.3 57.7 54.9 27.7 14.3 21.4 18.1 56.8 54.0 54.5 32.7 34.9 40.0 19.7 59.6 23.1 19.2 25.7 31.1 23.7 61.8 24.6 23.8 29.4 49.8 19.6 27.8 44.7 54.7 34.4 32.0 47.9 19.3 28.9 29.6 48.4 43.7 17.4 28.5 24.1 78.7 45.3 42.4 24.4 42.1 32.9 39.0 23.3 38.7 31.4 44.8 48.9 35.7 33.3 10.8 42.1 29.0 31.1 32.0 17.2 32.1 34.2 65.3 31.4 18.4 44.0 50.8 20.0 41.1 48.7 46.5 38.2 14.7 26.2 44.0 22.2 35.1 25.7 21.7 57.4 26.3 18.6 29.3 43.5 39.6 31.6 22.1 23.8 37.8 12.3 104.0 26.6 12.2 41.9 32.2 30.8 23.2 47.1 28.0 19.4 17.2 15.8 27.7 14.0 28.9 13.0 6.3 4.6 12.0 9.4 9.6 9.4 11.1 12.2 9.8 9.0 9.6 9.1 1.2 14.9 6.1 9.6 21.8 6.1 53.3 55.6 55.0 56.1 57.7 54.9 56.8 54.0 59.6 49.8 54.7 48.4 25.6 16.0 10.9 9.8 13.5 13.8 22.3 24.9 20.5 15.4 22.9 23.5 14.4 32.9 20.5 22.0 4.2 34.6 14.6 7.5 3.9 35.8 36.7 34.1 15.3 28.5 21.1 5.0 17.0 24.7 36.1 19.7 11.7 17.9 5.7 21.2 35.0 7.2 16.1 28.6 20.7 12.1 30.5 12.8 10.3 14.7 37.6 8.6 14.2 15.0 13.5 25.9 7.2 11.6 8.0 24.3 6.8 54.9 10.3 15.3 14.7 12.6 14.8 12.1 26.3 23.1 20.7 16.7 45.4 18.2 15.3 25.3 17.7 42.4 15.6 19.0 SLC46A1 "HCP1, MGC9564, PCFT" ENSG00000076351 "Solute carrier family 46 member 1" Q96NT5 17 28394642-28407197 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 93.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.6;Hepatocytes: 27.8;Hofbauer cells: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 5 "CACO-2: 205.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011614 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "CAB011614: AB_2270597" "unprognostic (1.10e-1)" "unprognostic (8.62e-2)" "unprognostic (1.40e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (9.11e-2)" "unprognostic (4.05e-2)" "unprognostic (1.36e-2)" "unprognostic (1.94e-1)" "unprognostic (3.80e-2)" "unprognostic (1.04e-3)" "unprognostic (6.15e-2)" "unprognostic (2.10e-3)" "unprognostic (2.16e-1)" "unprognostic (2.94e-1)" "unprognostic (2.15e-1)" "unprognostic (1.04e-1)" 6.7 24.8 8.1 5.7 10.6 3.4 5.7 14.7 9.2 5.6 26.7 5.7 93.9 4.6 8.5 2.4 13.4 4.6 4.6 8.0 8.4 7.5 27.3 6.9 5.5 11.2 9.7 8.7 11.2 15.0 15.5 8.2 10.4 7.4 5.6 8.7 12.5 9.0 3.6 2.3 40.5 5.5 9.8 11.1 5.5 3.1 10.0 23.4 6.4 2.8 2.1 5.0 2.6 12.1 5.4 22.5 7.4 12.2 5.9 1.3 22.9 6.3 4.6 5.1 5.7 205.4 6.4 0.4 3.6 3.4 14.8 17.3 8.4 14.1 4.3 13.1 19.6 0.2 14.0 17.6 2.1 0.1 10.1 2.8 25.3 5.3 15.8 7.1 0.4 1.8 8.9 1.2 0.9 7.2 0.1 0.6 4.4 5.2 2.9 0.3 6.0 2.7 4.0 11.8 19.4 10.2 43.6 20.1 2.4 10.1 15.6 3.4 0.6 0.8 8.6 1.2 6.6 9.0 11.1 0.3 1.2 1.3 4.7 5.2 0.9 0.6 0.4 3.0 0.7 1.6 0.4 0.3 1.4 0.8 0.5 0.8 1.0 1.6 2.6 0.5 0.9 0.5 8.1 10.6 14.7 9.2 8.0 8.4 11.2 9.7 10.4 9.8 10.0 12.1 1.2 12.8 5.3 7.5 1.0 0.4 1.9 2.8 4.0 26.6 5.1 6.1 2.3 17.2 2.2 7.3 4.2 20.8 0.2 3.7 0.0 3.5 3.6 18.2 1.8 1.9 1.2 0.4 2.8 4.6 9.7 3.6 3.1 1.5 1.3 4.2 1.8 27.8 25.7 20.2 4.6 2.4 0.0 21.5 1.0 19.5 4.1 8.0 0.0 5.6 2.0 2.2 0.0 8.0 6.9 3.8 3.6 3.4 3.0 2.6 3.9 4.6 4.3 6.0 6.6 3.7 1.4 0.3 0.3 1.2 0.3 4.4 0.6 5.8 1.3 1.6 SLC4A2 "AE2, BND3L, EPB3L1, HKB3, NBND3" ENSG00000164889 "Solute carrier family 4 member 2" P04920 7 151057210-151076526 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "choroid plexus: 492.1" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 91.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019339 Enhanced Uncertain "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles, Plasma membrane" Cytosol "HPA019339: AB_1844825" "unprognostic (1.19e-1)" "unprognostic (3.33e-3)" "unprognostic (8.12e-3)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (9.04e-6)" "unprognostic (1.24e-1)" "unprognostic (4.23e-1)" "unprognostic (3.30e-1)" "unprognostic (1.07e-1)" "unprognostic (3.21e-1)" "prognostic favorable (1.26e-4)" "unprognostic (4.67e-3)" "unprognostic (1.22e-1)" "unprognostic (1.28e-1)" "unprognostic (2.36e-2)" 28.4 34.8 16.9 19.2 29.4 12.7 23.7 29.1 21.9 38.9 492.1 45.0 22.5 40.3 4.9 21.0 31.1 19.7 31.3 39.4 23.2 38.6 52.3 33.2 13.1 32.8 27.9 31.9 52.5 72.4 13.8 27.0 32.0 28.2 7.1 4.7 23.1 14.0 18.8 21.7 29.3 16.5 20.2 27.0 82.2 13.7 32.7 12.4 25.4 12.3 6.3 31.9 25.8 40.2 60.9 196.9 37.8 78.9 37.6 17.9 87.1 72.9 37.0 56.9 48.0 113.0 91.6 35.8 154.1 35.0 84.6 58.2 38.2 31.4 9.8 105.3 59.1 48.5 91.9 57.5 59.6 25.2 147.0 29.0 27.4 65.6 15.7 60.9 31.3 50.6 151.8 27.1 44.3 118.0 69.2 43.3 90.4 80.7 73.2 55.2 21.2 42.2 44.6 41.0 31.5 113.9 67.0 118.4 62.0 27.3 51.2 46.7 72.0 78.1 39.1 77.5 106.5 31.2 47.7 20.5 118.7 61.4 160.6 0.0 1.6 0.4 0.8 1.6 0.7 0.9 0.7 0.7 1.0 0.3 0.7 0.8 0.2 0.1 1.0 2.1 0.2 0.9 16.9 29.4 29.1 21.9 39.4 23.2 32.8 27.9 32.0 20.2 32.7 40.2 15.6 9.6 8.2 9.8 7.2 11.1 5.9 13.6 15.4 7.7 14.5 11.9 4.0 18.6 9.6 20.2 25.0 36.1 14.2 17.6 17.6 35.7 1.0 21.9 18.9 13.6 27.6 2.5 0.4 35.8 9.4 13.6 30.1 17.0 47.1 62.1 17.9 34.6 26.0 15.2 1.4 12.1 16.2 16.1 12.0 1.6 13.7 17.0 26.6 4.7 11.6 21.6 3.1 3.0 16.8 43.8 14.0 19.9 9.9 5.9 24.9 19.1 11.4 8.2 13.1 12.8 17.6 3.1 7.9 10.6 7.0 91.5 8.5 11.2 22.1 4.5 SLC4A7 "NBC3, SBC2, SLC4A6" ENSG00000033867 "Solute carrier family 4 member 7" Q9Y6M7 3 27372721-27484420 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 57.6;retina: 72.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 733.9;Rod photoreceptor cells: 704.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "hTERT-HME1: 78.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022494, HPA035857" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Focal adhesion sites, Cytosol" "CAB022494: , HPA035857: AB_10795135" "unprognostic (2.94e-2)" "unprognostic (6.34e-2)" "unprognostic (1.80e-3)" "unprognostic (1.91e-1)" "unprognostic (8.48e-3)" "unprognostic (2.68e-1)" "unprognostic (6.79e-4)" "unprognostic (4.13e-2)" "unprognostic (1.40e-1)" "unprognostic (1.64e-1)" "unprognostic (1.83e-1)" "unprognostic (8.58e-3)" "prognostic unfavorable (7.91e-6)" "unprognostic (1.09e-2)" "unprognostic (6.68e-2)" "unprognostic (1.93e-1)" "unprognostic (7.26e-2)" 8.6 5.1 3.2 9.0 5.2 4.0 18.7 3.4 16.9 10.5 1.6 16.2 57.6 6.4 8.2 8.6 6.0 13.7 7.8 19.3 2.5 12.7 3.9 8.3 11.2 0.5 3.2 6.8 3.4 1.7 3.4 5.8 0.6 7.9 7.4 72.9 5.8 8.7 5.0 4.6 17.4 6.6 1.8 7.0 6.0 7.1 4.4 5.8 4.9 27.2 10.3 12.1 8.8 2.6 13.0 23.8 21.0 9.8 9.6 17.2 15.0 43.3 20.0 16.3 12.6 6.5 6.6 29.4 3.6 16.8 15.7 5.5 20.2 21.1 25.7 25.1 6.6 13.5 15.4 7.1 16.5 30.9 11.3 13.7 9.0 24.8 78.9 34.2 27.1 19.0 9.1 10.1 33.8 4.7 31.1 7.2 13.8 1.6 23.4 21.0 16.7 5.9 38.1 9.2 5.3 13.1 19.7 14.4 6.9 17.9 32.9 11.8 19.0 38.2 10.6 26.7 33.7 3.8 4.3 16.6 33.3 21.4 17.8 0.0 0.2 0.0 1.0 0.2 0.7 0.4 1.3 1.4 0.5 0.5 0.5 0.9 0.0 1.0 0.3 0.7 1.2 0.3 3.2 5.2 3.4 16.9 19.3 2.5 0.5 3.2 0.6 1.8 4.4 2.6 30.0 0.0 11.2 10.7 37.5 29.3 39.5 23.4 11.4 130.2 72.4 30.4 23.1 21.5 22.8 62.5 733.9 5.8 51.8 5.5 9.8 15.5 10.2 73.6 40.7 53.6 38.2 7.2 46.2 7.1 29.3 52.2 15.8 124.1 23.5 24.6 17.5 6.2 17.0 6.7 88.7 58.5 36.7 48.4 61.6 7.6 9.0 46.5 35.6 185.5 26.7 45.7 20.6 60.8 20.9 19.1 23.4 9.8 27.8 93.1 142.5 10.2 9.6 704.2 39.5 56.4 43.7 40.0 21.7 21.7 30.7 8.1 56.1 19.0 26.7 35.2 SLC5A12 "MGC52019, SMCT2" ENSG00000148942 "Solute carrier family 5 member 12" Q1EHB4 11 26667020-26723427 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 47.7;intestine: 30.1;kidney: 171.7" "Group enriched" "Detected in some" 23 "Proximal enterocytes: 286.0;Proximal tubular cells: 181.0" "Cancer enriched" "Detected in single" 26 "renal cancer: 9.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 2.3;NTERA-2: 1.7;SuSa: 3.3;T-47d: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA060904 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" Nucleoplasm "HPA060904: AB_2684385" "unprognostic (3.69e-3)" "unprognostic (6.92e-2)" "unprognostic (1.79e-1)" "unprognostic (2.86e-1)" "unprognostic (2.01e-2)" "unprognostic (9.35e-3)" "unprognostic (4.21e-3)" "unprognostic (4.49e-2)" "unprognostic (2.36e-3)" "unprognostic (1.71e-1)" "unprognostic (2.03e-2)" "unprognostic (3.43e-1)" "unprognostic (2.91e-3)" "unprognostic (1.34e-1)" "unprognostic (8.53e-2)" "unprognostic (1.42e-2)" "unprognostic (9.40e-3)" 0.1 0.1 0.3 0.0 0.5 0.9 0.1 0.9 0.4 0.0 0.3 0.2 4.9 0.1 47.7 0.0 0.1 0.1 4.3 0.3 0.4 171.7 1.7 0.1 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.6 0.2 0.1 0.2 1.0 0.1 0.1 0.1 0.3 30.1 0.0 0.0 0.6 0.3 0.2 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.5 0.2 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.2 1.7 0.3 0.0 0.0 0.0 0.3 0.0 0.5 0.8 0.1 0.7 0.1 0.0 3.3 1.2 0.2 0.2 0.2 0.1 0.2 0.1 1.0 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.5 0.9 0.4 0.3 0.4 0.2 0.1 0.2 0.0 0.2 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.1 3.7 0.0 0.1 0.0 2.4 9.8 0.0 1.4 0.2 0.0 0.2 0.0 0.0 0.7 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.3 6.7 0.0 0.0 0.0 0.2 0.0 0.7 0.0 1.0 0.0 0.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 286.0 181.0 0.1 0.3 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.6 4.5 3.5 0.1 SLC5A3 "SMIT, SMIT1" ENSG00000198743 "Solute carrier family 5 member 3" P53794 21 34073578-34106260 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 96.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 129.1;Collecting duct cells: 138.0;Granulosa cells: 148.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029791 Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA029791: AB_10601892" "unprognostic (9.70e-2)" "unprognostic (4.99e-2)" "unprognostic (2.23e-1)" "unprognostic (7.57e-2)" "unprognostic (1.07e-1)" "unprognostic (4.54e-2)" "unprognostic (4.48e-3)" "unprognostic (1.63e-1)" "unprognostic (3.02e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (1.98e-5)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.72e-4)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" "unprognostic (2.21e-1)" "unprognostic (8.60e-2)" 6.9 5.9 8.6 4.5 9.2 1.9 6.6 5.7 11.4 3.7 96.0 4.5 2.6 6.8 5.2 3.1 4.8 2.5 2.4 10.7 17.0 29.0 5.9 3.9 4.9 9.3 9.9 3.9 1.9 3.2 4.1 10.6 9.2 2.9 5.2 5.6 2.8 3.5 2.5 6.7 3.7 2.9 8.2 2.4 3.9 6.2 20.3 3.9 25.2 2.6 4.8 3.8 3.4 9.2 10.5 9.3 19.0 13.4 15.5 12.7 9.1 11.8 35.7 7.2 10.9 15.5 22.5 16.9 9.3 24.0 13.5 5.3 23.3 6.7 12.2 17.7 6.0 17.5 9.0 5.2 4.1 7.6 7.1 6.1 17.0 19.7 7.8 22.0 4.4 13.7 17.6 3.9 18.7 7.1 8.1 6.1 9.6 4.0 9.0 8.1 3.4 7.7 28.1 14.5 9.9 4.6 24.5 6.4 5.6 11.3 3.9 8.0 4.2 14.0 10.7 27.1 4.8 20.1 18.5 12.4 28.2 10.9 9.6 0.0 0.2 0.0 0.6 0.2 0.5 0.1 0.3 0.4 0.2 0.1 0.4 0.6 0.1 0.2 0.1 0.5 0.1 0.1 8.6 9.2 5.7 11.4 10.7 17.0 9.3 9.9 9.2 8.2 20.3 9.2 18.8 16.0 10.2 0.0 33.3 0.0 46.5 0.0 129.1 33.8 37.4 34.9 11.4 10.0 13.0 138.0 20.9 27.4 43.0 39.1 21.5 4.0 9.0 38.7 59.9 16.4 49.3 17.0 0.0 5.5 19.7 42.3 18.3 42.5 41.3 148.6 5.0 20.7 15.2 37.0 0.0 69.3 0.0 14.4 0.0 7.2 6.5 41.0 0.0 0.0 23.3 6.7 16.5 0.0 0.0 7.6 49.7 20.7 54.1 88.4 16.3 9.4 8.7 20.9 13.1 15.4 33.7 14.8 18.5 39.7 0.0 28.2 48.3 14.0 36.3 69.5 SLC7A2 "ATRC2, CAT-2, HCAT2" ENSG00000003989 "Solute carrier family 7 member 2" P52569 8 17497088-17570573 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 176.7;parathyroid gland: 224.1" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 93.1;Glandular and luminal cells: 139.8;Hepatocytes: 249.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 204.3;RT4: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009277 Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions" "HPA009277: AB_2668229" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (1.13e-2)" "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (7.24e-3)" "unprognostic (3.11e-1)" "unprognostic (1.76e-1)" "unprognostic (4.49e-1)" "unprognostic (1.34e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (2.65e-7)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.46e-2)" "unprognostic (8.98e-2)" "unprognostic (1.79e-1)" 28.6 11.6 7.9 3.4 7.0 0.2 17.2 9.5 9.6 32.5 16.6 6.2 2.4 15.2 17.8 11.3 42.5 11.2 12.2 10.0 8.0 8.0 176.7 7.5 2.7 14.1 6.2 84.4 83.1 224.1 7.1 9.8 12.6 14.2 4.3 17.6 5.1 7.2 114.5 8.1 4.5 13.4 12.7 3.8 8.3 15.4 7.1 3.1 45.1 45.8 3.5 10.5 14.9 15.9 0.0 3.1 1.0 32.4 0.2 0.3 35.1 0.3 22.1 1.7 2.0 10.7 0.1 0.0 7.4 0.0 4.7 0.0 23.5 5.4 7.4 0.0 12.3 0.0 24.8 23.2 204.3 10.3 0.0 27.7 4.5 27.2 25.7 0.0 10.2 0.0 0.2 0.0 24.9 35.5 1.3 11.7 11.8 7.4 2.9 0.0 16.2 17.6 2.7 55.3 0.4 4.3 1.7 0.8 9.9 23.5 0.0 1.2 22.9 0.0 11.8 0.1 0.1 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 7.0 9.5 9.6 10.0 8.0 14.1 6.2 12.6 12.7 7.1 15.9 9.4 12.8 78.1 58.8 0.4 8.3 6.6 5.8 20.5 2.9 52.0 25.8 15.5 38.6 16.3 7.3 35.5 22.6 0.1 0.4 0.0 8.3 12.8 67.0 40.4 5.6 87.9 10.7 0.5 93.1 15.1 20.6 0.5 139.8 2.5 0.4 7.1 249.0 5.8 0.0 19.9 3.6 0.0 6.7 2.3 22.9 37.9 1.4 3.6 1.9 0.6 23.5 0.0 11.6 2.6 20.5 0.6 27.8 0.1 50.2 0.3 3.7 53.9 38.0 59.2 8.8 75.7 0.3 1.1 7.8 3.8 26.0 1.6 9.5 3.2 8.4 SLC7A5 "CD98, D16S469E, E16, LAT1, MPE16" ENSG00000103257 "Solute carrier family 7 member 5" Q01650 16 87830023-87869507 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 110.7;brain: 121.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 178.7;Microglial cells: 109.6;Plasma cells: 135.1;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 17.2" "Lineage enriched" "Detected in many" 10 "dendritic cells: 17.2" "Cell line enhanced" "Detected in all" "HBEC3-KT: 1326.5;hTCEpi: 2229.0;MCF7: 1264.6;SiHa: 1873.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052673, HPA056077" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 51000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Cytosol" Vesicles "HPA052673: AB_2681909, HPA056077: AB_2683031" "unprognostic (2.71e-3)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (2.64e-1)" "unprognostic (3.22e-2)" "unprognostic (2.99e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (6.86e-2)" "unprognostic (4.46e-2)" "unprognostic (1.27e-1)" "unprognostic (3.17e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.93e-2)" "unprognostic (5.52e-3)" "unprognostic (1.64e-2)" "unprognostic (7.19e-3)" 10.6 3.9 121.9 18.3 87.8 110.7 6.0 89.5 119.4 11.0 64.5 11.4 6.6 5.2 35.7 100.2 6.4 6.6 21.1 96.0 91.0 18.0 26.6 9.8 14.1 111.3 104.3 8.1 14.0 1.8 22.8 17.0 104.9 9.8 2.7 42.5 28.6 10.4 30.1 25.1 8.9 3.2 93.0 16.7 34.4 65.6 117.1 6.9 3.9 2.8 11.5 24.6 22.6 88.1 187.4 693.5 13.2 192.1 5.1 10.6 487.3 147.1 52.8 87.4 56.3 456.3 260.4 170.1 126.7 187.6 30.5 818.3 142.5 1326.5 61.0 179.9 71.9 140.3 618.0 331.2 199.5 131.2 246.0 35.9 2229.0 107.8 791.4 28.5 18.0 588.8 212.6 185.1 71.1 1264.6 159.2 192.7 63.3 116.7 166.0 152.0 52.4 264.1 98.3 15.7 109.2 43.5 1873.1 368.9 406.9 123.0 170.0 171.8 14.3 30.9 201.3 127.8 114.5 237.9 213.2 728.2 120.1 322.1 296.4 1.0 0.0 0.0 1.0 0.0 1.3 0.5 0.5 0.9 0.4 0.0 0.1 0.4 0.2 0.2 0.0 17.2 1.6 0.5 121.9 87.8 89.5 119.4 96.0 91.0 111.3 104.3 104.9 93.0 117.1 88.1 3.7 0.0 0.6 8.1 23.0 73.3 17.9 27.0 178.7 15.2 12.0 8.9 2.9 2.8 6.3 1.8 16.7 15.4 80.0 3.4 0.0 18.1 1.0 20.5 7.6 29.1 86.3 86.3 12.0 9.6 35.4 9.5 43.3 51.0 66.9 4.5 1.8 17.3 9.2 10.1 13.2 6.3 8.2 3.0 50.5 5.0 1.8 51.0 39.2 109.6 2.6 14.8 2.1 15.1 1.6 25.7 2.3 1.5 135.1 18.2 1.0 0.4 3.2 52.7 0.0 33.6 31.5 1.6 4.5 58.8 37.5 107.4 65.8 2.7 4.2 42.8 SLC7A6 "KIAA0245, LAT-2, LAT3, y+LAT-2" ENSG00000103064 "Solute carrier family 7 member 6" Q92536 16 68264516-68301823 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 75.0" "Cell type enhanced" "Detected in many" "Microglial cells: 55.3;Syncytiotrophoblasts: 47.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050713 Uncertain Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Plasma membrane" "HPA050713: AB_2681218" "unprognostic (6.35e-2)" "unprognostic (4.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-2)" "unprognostic (1.24e-3)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.16e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (1.89e-3)" "unprognostic (7.82e-2)" "unprognostic (2.66e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.84e-4)" 35.3 8.8 1.7 15.5 1.9 8.4 26.9 6.5 3.3 5.5 17.3 8.3 3.9 5.8 11.5 4.5 8.6 4.4 18.5 3.3 2.2 5.9 2.0 10.9 18.6 1.0 1.3 2.7 3.8 2.5 9.6 18.6 1.5 6.2 11.1 5.0 7.3 5.2 75.0 10.2 12.0 7.7 1.0 10.7 6.6 5.1 2.2 37.6 16.7 26.9 21.5 6.8 4.8 1.1 22.6 22.1 16.3 16.8 46.9 27.6 42.9 24.9 18.7 36.9 30.6 97.9 16.2 43.7 19.8 33.4 10.9 33.1 32.0 32.2 39.7 9.5 22.9 23.8 47.3 31.0 7.7 28.2 20.3 19.3 26.1 27.5 13.5 11.4 25.3 21.0 35.1 7.3 20.5 11.7 36.4 19.3 12.4 14.6 8.1 45.0 10.2 36.0 12.0 19.6 23.7 13.5 75.7 20.8 6.8 13.4 30.9 13.3 38.4 24.6 19.0 20.5 32.8 16.7 33.5 50.3 15.6 20.1 17.2 3.4 3.2 2.8 4.3 1.7 5.4 6.8 6.6 4.3 3.6 6.3 11.7 6.7 6.1 7.1 1.4 16.8 3.1 1.5 1.7 1.9 6.5 3.3 3.3 2.2 1.0 1.3 1.5 1.0 2.2 1.1 8.5 41.7 18.8 12.4 18.4 19.6 9.3 8.5 13.6 6.1 5.9 4.8 19.9 2.8 4.9 18.4 37.5 25.1 23.3 7.3 0.0 3.3 5.5 10.7 16.8 12.0 2.4 2.1 39.3 4.0 2.5 12.8 4.1 3.3 4.5 1.8 6.8 1.4 14.6 10.1 40.3 10.5 4.1 8.5 12.1 18.3 5.9 9.9 10.6 55.3 10.0 1.8 14.4 13.0 10.7 5.6 5.9 3.8 16.0 8.0 2.5 0.6 10.4 2.7 0.0 10.8 7.2 17.3 10.9 6.7 21.9 47.9 23.5 4.3 7.8 2.6 SLC8A1 NCX1 ENSG00000183023 "Solute carrier family 8 member A1" P32418 2 40097270-40611053 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 117.5" "Group enriched" "Detected in many" 8 "Cardiomyocytes: 743.1;Excitatory neurons: 1267.5;Inhibitory neurons: 631.3;Microglial cells: 574.3;Oligodendrocyte precursor cells: 753.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.2" "Group enriched" "Detected in many" 6 "granulocytes: 44.2;monocytes: 11.5" "Cell line enhanced" "Detected in many" "BJ: 28.9;fHDF/TERT166: 70.4;hTERT-HME1: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022694, HPA070007" Uncertain Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane" "CAB022694: , HPA070007: AB_2686227" "unprognostic (2.46e-1)" "unprognostic (1.33e-2)" "unprognostic (1.42e-2)" "unprognostic (7.57e-6)" "unprognostic (1.56e-1)" "unprognostic (3.94e-1)" "unprognostic (2.28e-2)" "unprognostic (4.60e-2)" "unprognostic (1.31e-1)" "unprognostic (7.71e-2)" "unprognostic (1.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.66e-2)" "unprognostic (7.04e-3)" "unprognostic (3.93e-2)" "unprognostic (5.46e-2)" "unprognostic (6.77e-2)" 6.1 4.0 25.7 7.2 25.8 2.0 1.6 0.0 28.0 4.7 0.0 9.6 5.0 19.7 5.6 5.9 5.6 6.5 117.5 30.6 11.0 17.5 3.1 5.8 3.3 1.5 19.8 2.5 1.8 0.7 0.8 11.2 0.7 18.8 4.8 5.9 1.0 27.1 0.3 1.5 5.5 23.4 2.7 7.3 3.5 0.7 19.5 2.0 0.8 0.9 1.5 8.9 2.5 24.1 3.0 2.2 2.1 0.2 3.1 6.4 0.0 28.9 11.1 9.4 6.1 0.0 4.7 0.1 2.2 70.4 10.1 1.1 0.5 4.8 9.5 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.5 3.7 0.0 10.8 19.8 4.3 0.7 0.0 0.0 0.4 12.1 0.0 0.9 0.1 1.4 0.3 4.0 7.8 14.8 0.0 3.3 0.4 3.2 0.6 0.0 0.0 0.0 9.7 0.1 0.6 9.8 8.8 0.3 0.0 3.1 1.6 0.0 0.0 1.4 1.7 1.4 0.0 8.3 0.0 0.0 9.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 44.2 0.0 11.5 0.3 0.0 1.1 25.7 25.8 0.0 28.0 30.6 11.0 1.5 19.8 0.7 2.7 19.5 24.1 10.3 3.2 2.8 39.5 3.6 1.3 0.0 0.2 1.2 79.1 0.5 5.8 743.1 2.8 0.6 35.0 4.2 0.5 0.3 0.0 0.0 0.0 1.1 2.3 52.8 15.1 0.0 3.0 1267.5 0.0 1.6 26.6 1.5 3.0 0.0 0.2 12.1 0.3 29.3 0.0 631.3 2.5 0.0 78.0 26.7 1.4 0.0 88.8 1.8 574.3 42.7 32.0 1.0 753.0 20.5 0.1 3.8 8.2 0.7 0.2 24.7 0.5 0.0 7.2 13.1 1.4 46.6 0.2 1.2 0.5 3.1 1.1 1.2 0.7 2.5 0.1 SLC9A1 "APNH, NHE1, PPP1R143" ENSG00000090020 "Solute carrier family 9 member A1" P19634 1 27098809-27166981 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" Calmodulin-binding "Deafness, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 76.5;stomach 1: 65.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 81.5;Gastric mucus-secreting cells: 160.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022371, HPA048532, HPA052891" Enhanced Supported "Plasma membrane" NA NA 21000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB022371: , HPA048532: AB_2680431, HPA052891: AB_2681981" "unprognostic (6.18e-2)" "unprognostic (1.59e-1)" "unprognostic (2.21e-1)" "unprognostic (8.48e-2)" "prognostic unfavorable (7.47e-4)" "unprognostic (2.70e-2)" "unprognostic (4.33e-3)" "unprognostic (3.18e-2)" "unprognostic (9.74e-2)" "prognostic unfavorable (7.10e-4)" "unprognostic (3.44e-2)" "unprognostic (6.95e-2)" "unprognostic (2.05e-2)" "unprognostic (1.27e-2)" "unprognostic (1.60e-1)" "unprognostic (3.34e-1)" "unprognostic (1.16e-2)" 9.6 10.7 6.1 10.4 14.7 11.5 9.0 2.8 10.8 10.9 0.2 18.6 29.3 10.9 8.0 11.0 7.6 16.9 13.7 2.3 5.3 5.8 2.4 13.2 7.0 13.8 4.7 7.0 8.6 20.7 8.2 21.9 11.2 9.0 13.6 4.5 76.5 19.4 4.6 10.5 19.0 10.7 0.5 11.6 65.9 10.1 10.4 6.3 9.5 4.9 6.7 15.1 9.2 2.4 32.3 10.7 9.9 10.1 21.8 15.7 60.8 25.9 38.5 21.7 23.5 13.0 20.0 14.4 21.9 33.4 10.5 38.9 9.8 62.4 13.4 17.4 9.4 21.9 7.1 5.5 66.1 13.1 16.0 19.7 29.5 36.5 50.7 15.8 36.3 9.8 6.3 13.4 32.3 18.7 6.8 6.4 14.0 38.2 21.9 11.8 9.0 6.7 10.9 46.3 11.4 3.7 21.5 28.4 12.6 10.0 13.3 7.9 39.9 23.0 9.4 21.7 14.5 12.6 8.6 4.3 24.6 14.1 13.5 0.0 0.6 0.6 0.7 0.3 1.5 0.1 0.8 0.7 0.2 0.3 0.5 0.6 2.0 0.1 0.6 0.0 0.3 0.8 6.1 14.7 2.8 10.8 2.3 5.3 13.8 4.7 11.2 0.5 10.4 2.4 13.5 6.4 14.8 6.5 7.9 31.2 17.9 14.6 13.1 7.4 21.7 23.2 13.5 7.2 8.3 11.0 0.0 40.3 11.9 81.5 0.0 9.1 26.5 13.8 15.9 9.7 12.5 0.4 14.1 12.5 19.4 12.7 160.0 26.5 27.3 7.5 6.8 1.2 12.9 20.2 14.1 15.0 4.1 5.7 5.1 14.4 9.3 12.7 7.2 8.4 4.3 8.2 12.3 4.0 4.6 28.1 43.1 13.2 4.8 9.6 38.9 1.2 5.9 3.8 6.6 20.8 9.8 3.6 4.4 15.0 25.1 52.9 9.8 4.8 18.3 18.3 SLC9A3 NHE3 ENSG00000066230 "Solute carrier family 9 member A3" P48764 5 470456-524449 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 45.4;intestine: 94.3;kidney: 62.5;stomach 1: 50.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Collecting duct cells: 16.5;Proximal tubular cells: 40.7" "Cancer enhanced" "Detected in many" "stomach cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 37.8" "Region enriched" "Detected in single" 14 "cerebellum: 4.1" "Low region specificity" "Detected in many" "HPA036493, HPA036669" Enhanced Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA036493: AB_10673353, HPA036669: AB_10670843" "unprognostic (1.27e-1)" "unprognostic (4.88e-1)" "unprognostic (9.35e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (3.35e-1)" "unprognostic (2.51e-1)" "unprognostic (9.40e-2)" "prognostic unfavorable (8.49e-4)" "unprognostic (5.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.69e-2)" "unprognostic (3.84e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" "unprognostic (1.24e-2)" "unprognostic (1.32e-1)" 2.9 4.4 3.0 10.4 2.5 1.9 3.1 6.1 5.0 3.8 1.7 94.3 46.0 2.9 4.0 8.7 4.9 45.4 3.2 4.7 2.5 62.5 2.4 2.8 3.8 3.8 2.3 4.3 6.7 6.2 0.7 2.1 3.7 7.3 10.8 1.7 9.9 3.8 6.2 19.0 68.1 3.3 1.3 3.7 50.1 5.8 3.4 3.5 4.9 3.9 3.4 2.5 2.5 2.6 6.7 5.1 10.4 10.5 2.5 3.0 7.8 5.3 3.9 8.0 5.0 11.0 7.4 14.0 7.5 3.0 5.5 10.0 6.1 4.0 3.9 37.8 10.7 6.7 23.4 5.4 3.9 5.5 8.2 4.2 8.1 3.5 5.4 3.9 2.4 6.3 9.6 7.5 2.9 9.0 6.0 24.3 4.0 17.8 8.3 8.6 9.3 8.3 2.8 4.8 11.5 5.0 19.0 5.3 4.2 4.5 12.3 4.2 2.9 8.0 7.2 5.3 3.9 12.4 5.8 8.5 5.2 21.2 5.6 0.0 0.7 0.1 2.6 0.3 2.2 0.9 3.3 2.4 0.9 1.0 3.9 3.1 0.1 2.4 0.2 1.2 2.7 1.8 3.0 2.5 6.1 5.0 4.7 2.5 3.8 2.3 3.7 1.3 3.4 2.6 3.8 16.0 5.8 0.0 1.5 0.0 0.0 0.0 0.0 0.0 7.3 8.9 0.7 0.0 5.6 16.5 0.0 0.0 3.4 0.7 5.9 9.0 0.0 3.8 3.6 2.3 0.0 0.0 0.3 8.8 0.0 2.2 0.0 2.6 2.5 5.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 4.6 0.0 0.0 0.0 0.1 7.7 0.0 0.0 0.7 0.0 1.1 40.7 2.9 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 2.3 5.4 0.0 0.0 SLC9A3R2 "E3KARP, NHERF-2, SIP-1, TKA-1" ENSG00000065054 "SLC9A3 regulator 2" Q15599 16 2025356-2039026 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 568.2" "Cell type enhanced" "Detected in many" "Adipocytes: 1013.8;Endothelial cells: 398.9;Hepatic stellate cells: 374.4;Hepatocytes: 227.4;Pancreatic endocrine cells: 326.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.2;intermediate monocyte: 1.6;myeloid DC: 3.9;plasmacytoid DC: 2.9" "Group enriched" "Detected in many" 5 "dendritic cells: 3.9;monocytes: 2.2" "Cell line enhanced" "Detected in many" "A549: 188.6;MCF7: 306.8;PC-3: 281.2;SK-BR-3: 188.3;U-251 MG: 193.6;WM-115: 202.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001672, HPA066520" Enhanced Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA001672: AB_1080017, HPA066520: AB_2732748" "unprognostic (6.99e-2)" "unprognostic (4.56e-2)" "unprognostic (2.06e-2)" "prognostic favorable (1.03e-4)" "unprognostic (1.41e-2)" "unprognostic (1.54e-1)" "unprognostic (2.94e-3)" "unprognostic (9.17e-2)" "unprognostic (1.68e-2)" "unprognostic (1.56e-2)" "unprognostic (2.17e-2)" "unprognostic (1.70e-2)" "unprognostic (2.20e-2)" "unprognostic (6.20e-3)" "unprognostic (9.10e-2)" "unprognostic (2.40e-1)" "unprognostic (2.80e-2)" 234.7 81.7 107.0 20.7 98.6 0.7 181.7 83.4 119.7 92.6 60.6 77.4 27.2 92.7 10.7 47.3 77.7 34.8 568.2 82.4 88.5 207.5 408.3 289.1 22.0 96.4 95.5 57.9 47.7 24.0 95.6 51.3 99.3 129.1 11.9 3.0 149.1 42.4 144.6 45.3 81.2 18.8 87.0 143.8 109.5 36.3 116.2 7.9 188.4 109.0 7.4 77.4 72.6 94.7 32.5 188.6 5.0 38.6 6.2 8.6 5.7 138.1 81.9 67.9 22.5 25.4 41.9 0.1 63.4 59.2 9.1 30.9 15.0 13.7 7.1 0.4 45.0 3.1 80.8 61.6 44.3 0.5 13.9 9.2 13.7 20.2 5.9 32.1 68.2 15.0 24.0 2.9 4.8 306.8 0.6 35.7 7.5 76.8 281.2 27.6 8.1 50.5 16.0 2.9 35.3 33.1 9.7 188.3 12.8 5.0 152.6 16.8 176.4 21.5 30.7 1.9 193.6 5.1 4.6 0.7 2.5 3.6 202.4 0.0 2.2 0.0 0.5 1.6 0.2 0.0 0.1 0.1 3.9 0.0 0.4 0.5 0.0 0.0 0.5 2.9 0.1 0.7 107.0 98.6 83.4 119.7 82.4 88.5 96.4 95.5 99.3 87.0 116.2 94.7 1013.8 3.2 10.5 4.2 7.3 15.2 19.6 17.1 7.4 2.6 79.5 65.0 25.5 88.6 47.3 12.9 0.0 1.0 11.4 13.3 5.9 36.1 16.1 37.2 36.8 398.9 21.5 17.3 3.4 8.8 0.8 53.5 33.6 67.8 0.0 5.1 374.4 227.4 2.6 3.3 5.5 77.0 22.4 30.9 35.1 35.8 82.0 7.0 33.8 31.9 2.2 17.2 7.2 4.0 3.6 326.8 9.3 44.4 4.9 51.8 1.2 14.7 27.3 5.0 26.3 22.3 69.1 7.0 15.4 3.4 11.4 1.0 8.8 9.5 18.0 66.6 SLC9A5 NHE5 ENSG00000135740 "Solute carrier family 9 member A5" Q14940 16 67237683-67272191 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.6;lymphoid tissue: 17.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 11.1;Horizontal cells: 16.8;Inhibitory neurons: 12.2;Oligodendrocyte precursor cells: 7.1;Spermatocytes: 17.2;Theca cells: 6.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-138 MG: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041004, HPA041329" Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Plasma membrane" "HPA041004: AB_10794433, HPA041329: AB_10794373" "unprognostic (8.90e-2)" "unprognostic (9.70e-2)" "unprognostic (3.39e-3)" "unprognostic (1.37e-1)" "unprognostic (1.44e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-2)" "unprognostic (5.17e-2)" "unprognostic (1.50e-1)" "unprognostic (1.12e-1)" "unprognostic (2.50e-3)" "unprognostic (4.84e-2)" "unprognostic (9.85e-11)" "unprognostic (9.21e-2)" "unprognostic (1.95e-1)" "unprognostic (8.12e-3)" "unprognostic (9.07e-2)" 0.9 0.6 4.2 0.3 6.6 0.1 1.0 5.4 6.5 0.8 2.5 0.5 0.4 0.4 1.0 0.2 0.5 0.6 1.6 4.6 3.9 0.8 0.2 1.4 0.8 4.8 4.1 1.2 0.6 0.1 0.8 0.6 5.3 0.9 0.3 1.2 0.8 0.3 1.8 1.5 0.5 0.1 3.4 17.4 0.5 3.2 4.2 0.1 0.8 0.7 0.4 0.4 0.5 4.0 0.3 2.9 2.6 0.9 4.7 3.2 0.3 1.1 4.1 2.4 2.2 0.1 2.0 0.0 0.6 1.2 1.2 0.1 0.6 0.4 1.0 0.8 0.8 2.1 0.5 0.7 0.5 1.0 4.7 3.8 1.0 1.5 0.2 4.5 1.0 0.9 0.5 1.3 1.6 1.7 0.0 0.2 1.5 0.2 0.2 0.0 0.5 0.7 0.4 0.5 1.6 0.9 2.4 0.1 1.2 0.6 1.1 0.2 0.8 6.4 0.9 1.1 0.4 2.4 0.5 1.3 4.5 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 4.2 6.6 5.4 6.5 4.6 3.9 4.8 4.1 5.3 3.4 4.2 4.0 0.6 3.2 2.8 4.2 0.4 0.6 0.2 0.1 1.2 3.4 1.8 1.3 1.5 1.5 0.2 0.0 0.0 0.3 0.1 0.5 0.0 0.3 1.8 0.2 0.8 0.8 1.2 0.0 11.1 0.2 0.1 0.7 0.0 0.9 0.0 0.9 1.4 0.0 0.1 16.8 12.2 0.3 0.0 0.0 0.4 0.7 0.3 0.5 0.0 1.9 0.6 0.3 0.0 7.1 2.6 0.5 0.1 2.2 0.0 0.5 0.2 0.0 0.7 0.9 0.0 0.6 1.4 17.2 4.6 0.3 0.9 0.0 0.3 6.8 0.3 0.2 SLCO1A2 "OATP, OATP-A, OATP1A2, SLC21A3" ENSG00000084453 "Solute carrier organic anion transporter family member 1A2" P46721 12 21264600-21419594 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 82.0;choroid plexus: 28.6" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 487.6" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "NTERA-2: 16.7;RPMI-8226: 12.0;SuSa: 16.1;U-266/70: 23.1;U-266/84: 9.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071152 Supported "Plasma membrane" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA071152: AB_2686350" "unprognostic (5.43e-3)" "unprognostic (2.33e-1)" "unprognostic (1.28e-1)" "unprognostic (8.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.36e-2)" "unprognostic (7.63e-2)" "unprognostic (1.53e-1)" "unprognostic (3.82e-2)" "unprognostic (1.54e-2)" "unprognostic (1.51e-1)" "unprognostic (8.82e-2)" "unprognostic (1.66e-4)" "unprognostic (2.52e-2)" "unprognostic (3.20e-1)" "unprognostic (1.24e-1)" 0.0 0.1 48.9 0.1 65.9 0.1 4.0 43.5 80.2 0.0 28.6 0.1 0.0 0.1 0.2 0.1 0.3 0.2 0.9 41.3 46.4 1.2 11.5 2.8 0.7 54.0 51.9 0.2 2.4 0.2 0.4 1.2 52.6 0.7 0.0 0.6 15.8 0.0 0.4 0.5 0.1 0.0 45.2 0.5 0.3 1.9 48.3 0.6 0.2 0.0 0.4 0.2 0.0 82.0 2.1 0.6 0.8 0.1 0.0 0.0 3.4 0.0 0.0 0.1 0.0 3.8 1.4 0.1 2.1 0.2 0.0 0.3 0.3 0.2 0.5 0.7 0.9 0.0 0.5 1.5 0.0 0.4 0.3 0.0 1.7 0.2 0.2 1.5 0.1 0.4 4.0 1.2 0.0 2.6 0.4 0.1 16.7 2.0 0.2 0.2 0.2 12.0 0.0 2.2 1.9 2.9 0.0 0.2 0.2 16.1 3.2 0.9 0.0 0.1 1.7 0.8 0.4 23.1 9.8 0.2 0.1 0.3 0.0 0.2 0.1 0.1 0.4 0.1 0.6 0.4 0.6 0.4 0.0 0.2 0.6 0.4 1.3 0.3 0.0 0.2 0.5 0.1 48.9 65.9 43.5 80.2 41.3 46.4 54.0 51.9 52.6 45.2 48.3 82.0 0.0 35.3 3.1 5.9 0.0 0.0 0.0 0.0 0.0 0.2 3.5 2.8 0.5 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.0 0.0 2.8 0.0 0.0 0.7 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.8 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 102.1 0.0 0.1 0.0 2.5 487.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.4 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 SLCO1B1 "LST-1, OATP-C, OATP1B1, SLC21A6" ENSG00000134538 "Solute carrier organic anion transporter family member 1B1" Q9Y6L6 12 21131194-21239796 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 614 "liver: 537.2" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 83.1" "Cancer enriched" "Detected in some" 96 "liver cancer: 52.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 1.1;NTERA-2: 1.3;RPMI-8226: 1.8;SuSa: 2.2" "HPA050892, HPA073093" Supported Supported "Plasma membrane" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA050892: AB_2681265, HPA073093: " "unprognostic (5.45e-1)" "unprognostic (1.82e-4)" "unprognostic (2.43e-3)" "unprognostic (1.96e-3)" "unprognostic (1.80e-1)" "unprognostic (2.41e-1)" "unprognostic (8.82e-2)" "unprognostic (5.63e-2)" "unprognostic (3.86e-2)" "unprognostic (3.49e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 537.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.2 0.1 0.2 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 83.1 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 SLCO1B3 "OATP1B3, OATP8, SLC21A8" ENSG00000111700 "Solute carrier organic anion transporter family member 1B3" Q9NPD5 12 20810702-20916911 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 265.1" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 203.4" "Cancer enriched" "Detected in many" 4 "liver cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 65.3;A549: 17.5;CAPAN-2: 12.6;GAMG: 13.6;HeLa: 14.2;PC-3: 17.3;U-2 OS: 14.7" "HPA004943, HPA050892" Enhanced Supported "Plasma membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA004943: AB_1854758, HPA050892: AB_2681265" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (6.95e-2)" "unprognostic (1.63e-2)" "unprognostic (1.89e-2)" "unprognostic (7.09e-2)" "unprognostic (3.08e-2)" "unprognostic (1.54e-2)" "unprognostic (7.37e-2)" "unprognostic (1.50e-1)" "unprognostic (6.61e-3)" "unprognostic (2.36e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 13.0 16.2 0.3 0.2 0.1 0.4 0.3 0.0 0.3 0.0 0.5 0.0 0.0 265.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 1.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 65.3 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 12.6 0.0 4.3 0.0 13.6 0.1 0.0 0.5 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.9 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 14.7 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 203.4 0.0 0.0 0.5 0.0 0.0 1.6 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.2 SLCO5A1 "OATP-J, OATP5A1, OATPRP4, SLC21A15" ENSG00000137571 "Solute carrier organic anion transporter family member 5A1" Q9H2Y9 8 69667046-69834978 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.5;skeletal muscle: 7.6;tongue: 11.1" "Group enriched" "Detected in many" 4 "Bipolar cells: 10.1;Cardiomyocytes: 14.4;Enteroendocrine cells: 15.6;Excitatory neurons: 8.6;Inhibitory neurons: 30.1;monocytes: 21.2;Oligodendrocyte precursor cells: 26.2;Plasma cells: 14.3;Prostatic glandular cells: 11.8" "Cancer enhanced" "Detected in some" "prostate cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 5.5;NTERA-2: 3.7;RPMI-8226: 3.6;SCLC-21H: 3.9;U-266/70: 2.1" "Group enriched" "Detected in some" 7 "basal ganglia: 2.3;olfactory bulb: 6.7" "Region enriched" "Detected in some" 7 "olfactory bulb: 12.8" HPA025062 Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA025062: AB_1857220" "unprognostic (1.30e-3)" "unprognostic (7.35e-3)" "unprognostic (4.13e-2)" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "unprognostic (5.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.37e-4)" "unprognostic (1.75e-1)" "unprognostic (4.48e-4)" "unprognostic (1.74e-2)" "unprognostic (2.92e-6)" "unprognostic (2.20e-1)" "unprognostic (1.23e-1)" "unprognostic (2.13e-1)" "unprognostic (4.50e-2)" 0.1 0.0 0.3 0.9 0.4 0.9 0.1 0.0 0.4 0.2 0.0 0.2 0.2 0.2 0.0 0.5 0.3 0.2 3.7 0.2 0.6 0.0 0.0 0.1 1.0 0.2 0.0 0.0 0.4 0.0 1.5 0.0 0.2 2.3 0.4 0.7 0.3 0.0 7.6 0.1 0.3 0.1 0.0 0.5 0.2 0.3 0.1 6.5 0.0 11.1 0.9 0.6 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 1.5 1.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 3.7 0.0 0.6 0.6 0.6 3.6 0.0 0.0 3.9 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 2.1 0.3 0.0 0.2 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.4 0.2 0.6 0.2 0.0 0.2 0.0 0.1 0.1 0.1 3.2 0.0 3.6 3.6 0.3 1.8 0.0 0.6 10.1 0.2 0.3 14.4 0.0 0.6 0.0 2.1 0.0 0.0 0.6 0.0 1.8 0.6 0.4 1.7 2.0 15.6 0.0 8.6 1.3 0.0 4.0 0.0 1.7 0.0 0.0 0.0 0.2 0.1 1.7 30.1 2.0 0.0 0.0 3.6 0.6 0.0 0.7 0.0 3.7 21.2 0.5 0.0 26.2 2.2 2.1 0.1 0.0 14.3 11.8 0.0 0.1 0.0 0.3 0.0 3.4 2.0 1.1 2.6 0.4 0.4 0.0 0.1 0.4 1.5 1.5 SLITRK6 FLJ22774 ENSG00000184564 "SLIT and NTRK like family member 6" Q9H5Y7 13 85792790-85806683 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hearing, Sensory transduction, Vision" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 27.7;urinary bladder: 14.7" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 22.8;Bipolar cells: 41.7;Club cells: 27.4;Ionocytes: 16.2;Respiratory ciliated cells: 41.6" "Cancer enhanced" "Detected in many" "breast cancer: 21.1;urothelial cancer: 18.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 28.8;OE19: 24.2;RT4: 101.4;WM-115: 23.7" "Region enhanced" "Detected in many" "thalamus: 22.6" "Low region specificity" "Detected in many" "HPA014491, HPA014513" Uncertain Supported "Plasma membrane" NA NA 28000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA014491: AB_10601603, HPA014513: AB_2669026" "unprognostic (6.14e-2)" "unprognostic (5.21e-3)" "unprognostic (1.40e-1)" "unprognostic (2.66e-2)" "unprognostic (2.46e-2)" "prognostic unfavorable (8.52e-4)" "unprognostic (6.10e-2)" "unprognostic (1.72e-2)" "unprognostic (1.69e-1)" "unprognostic (4.82e-2)" "unprognostic (7.60e-2)" "unprognostic (7.92e-2)" "unprognostic (3.31e-5)" "unprognostic (5.60e-2)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (2.51e-2)" 0.1 0.2 1.0 0.9 4.4 0.0 3.2 2.2 1.9 1.2 0.1 5.5 3.5 1.0 2.5 1.9 0.5 1.4 1.5 0.2 2.0 0.1 0.9 3.3 0.0 0.6 2.3 0.0 0.2 0.0 0.1 0.9 0.9 7.6 6.8 4.8 27.7 2.2 0.0 5.6 5.7 0.4 0.3 0.1 1.5 0.3 5.7 0.2 0.3 0.1 0.1 14.7 1.4 0.4 0.0 2.9 0.1 0.5 0.0 0.0 0.0 2.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 4.9 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 28.8 0.0 3.3 2.7 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.0 0.0 24.2 1.9 0.2 0.0 0.0 0.0 101.4 1.0 1.2 0.5 0.1 0.1 1.7 0.5 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 23.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 4.4 2.2 1.9 0.2 2.0 0.6 2.3 0.9 0.3 5.7 0.4 0.1 0.0 1.8 0.0 0.0 3.8 5.0 22.8 0.0 41.7 5.3 1.5 0.4 0.0 27.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.2 4.3 0.3 0.0 0.0 0.1 0.0 0.0 2.0 0.0 2.7 0.0 2.2 2.2 0.0 0.2 0.0 0.4 1.7 16.2 0.0 0.6 0.0 9.6 0.1 0.0 1.0 0.0 0.6 0.0 0.0 0.0 1.8 0.0 0.4 0.0 1.5 0.0 0.1 41.6 2.0 0.0 0.0 0.8 0.0 0.1 3.8 2.4 0.0 0.2 0.1 0.5 4.5 SMAGP "hSMAGP, MGC149453, MGC149454" ENSG00000170545 "Small cell adhesion glycoprotein" Q0VAQ4 12 51244558-51270415 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 139.8;placenta: 102.1" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 1219.9;Syncytiotrophoblasts: 842.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 131.2;OE19: 163.9" "Low region specificity" "Detected in all" HPA039711 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA039711: AB_10674985" "unprognostic (2.55e-3)" "unprognostic (2.63e-1)" "unprognostic (3.96e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.01e-1)" "unprognostic (1.63e-3)" "unprognostic (6.26e-2)" "unprognostic (7.48e-2)" "unprognostic (9.11e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.46e-1)" "prognostic favorable (2.24e-4)" "unprognostic (4.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.99e-2)" "unprognostic (1.52e-1)" 14.0 17.2 2.7 9.9 2.7 3.5 16.1 5.2 3.2 33.8 3.4 57.5 17.6 6.5 20.7 139.8 8.3 16.2 10.3 3.0 2.5 43.0 10.2 17.7 6.0 2.8 2.9 11.4 16.5 11.1 4.3 102.1 2.8 10.5 59.3 1.0 24.1 8.6 3.4 34.8 19.6 8.5 2.6 13.7 35.9 8.1 3.3 1.5 8.7 6.8 27.6 17.5 67.9 3.0 81.6 24.2 2.9 2.7 10.5 40.9 131.2 61.1 60.9 30.6 18.7 48.9 83.2 1.0 10.5 37.9 11.6 28.3 17.1 23.5 42.6 4.1 14.2 10.9 3.3 16.5 28.8 2.7 10.1 26.7 17.8 66.3 59.4 69.4 74.6 20.6 8.7 4.7 49.9 71.4 13.4 9.8 12.3 163.9 93.9 0.8 0.8 3.1 44.0 18.5 3.3 4.1 13.4 53.2 10.2 31.3 45.0 4.2 26.1 33.9 32.7 1.7 37.8 1.7 2.4 1.6 49.8 26.3 18.7 4.6 6.6 12.0 15.4 4.6 10.0 36.9 6.8 11.1 4.7 38.1 6.3 11.0 16.0 19.8 5.4 2.9 5.3 6.8 2.7 2.7 5.2 3.2 3.0 2.5 2.8 2.9 2.8 2.6 3.3 3.0 44.1 0.0 25.7 0.3 26.3 21.7 74.3 35.5 12.0 1.3 23.4 25.8 1.7 55.8 44.7 16.5 0.0 1219.9 21.7 85.0 49.0 43.6 11.7 4.8 2.3 60.9 20.4 8.6 0.6 108.7 108.0 11.4 47.9 8.7 12.7 19.7 51.4 6.7 96.8 1.7 0.5 121.5 26.4 6.3 11.2 3.2 13.1 6.1 14.2 6.5 7.9 4.1 38.1 0.0 0.5 142.5 88.1 9.8 5.7 73.7 35.0 22.6 17.4 1.7 26.3 4.8 11.1 6.2 31.3 80.7 29.7 842.5 13.8 9.8 121.7 105.2 SNAP23 "HsT17016, SNAP23A, SNAP23B" ENSG00000092531 "Synaptosome associated protein 23" O00161 15 42491233-42545356 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 326.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 675.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001214, CAB037083, CAB037317" Approved Supported "Plasma membrane" NA NA 3900000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "CAB037083: AB_477494, CAB037317: AB_261925, HPA001214: AB_1080037" "unprognostic (1.77e-1)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (3.76e-3)" "unprognostic (2.42e-2)" "unprognostic (1.65e-1)" "unprognostic (9.67e-3)" "unprognostic (1.60e-1)" "unprognostic (2.60e-1)" "unprognostic (2.93e-1)" "unprognostic (7.31e-2)" "unprognostic (1.36e-1)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (8.95e-2)" "unprognostic (1.10e-1)" "unprognostic (3.93e-2)" 44.4 30.3 23.0 62.9 27.7 35.1 38.2 25.7 46.3 37.5 28.6 52.8 50.3 43.2 35.3 31.9 29.8 40.2 44.6 23.5 24.8 42.4 44.4 45.2 84.6 28.0 25.9 34.6 24.2 36.2 12.9 68.9 31.3 49.2 51.2 12.8 45.2 30.9 43.9 26.5 56.4 48.3 25.6 70.3 39.9 36.1 27.5 38.0 33.1 28.7 78.7 42.5 23.9 37.2 58.3 29.7 55.7 54.7 91.8 70.4 85.1 77.6 61.8 50.8 59.1 93.0 27.8 35.1 91.3 52.3 48.1 52.7 63.2 50.1 70.9 58.4 35.3 149.2 30.5 89.1 66.8 57.4 136.6 59.1 37.9 43.5 70.4 64.7 192.9 69.4 121.6 31.4 67.1 24.1 68.3 69.4 46.0 94.3 22.8 122.4 33.8 55.1 71.8 57.8 9.0 36.3 57.2 51.3 56.4 83.5 76.2 91.6 155.0 46.6 61.2 52.1 80.4 59.1 122.3 153.2 56.3 120.0 62.8 244.8 159.8 675.6 51.4 237.6 60.2 110.2 53.5 50.2 148.2 103.9 68.0 52.4 361.9 70.7 236.0 62.6 66.4 179.4 23.0 27.7 25.7 46.3 23.5 24.8 28.0 25.9 31.3 25.6 27.5 37.2 58.9 112.2 30.5 30.7 79.0 50.7 107.6 30.8 34.7 7.7 41.9 19.8 19.2 38.6 32.8 20.2 20.9 75.9 45.3 61.3 56.7 71.1 207.6 34.4 38.6 77.1 14.9 25.0 21.2 52.2 109.5 44.3 32.6 41.2 83.5 22.4 77.4 28.0 88.9 5.0 23.6 80.2 52.9 125.4 112.8 326.0 39.1 131.8 44.4 36.5 120.0 14.6 53.5 39.7 54.6 110.8 52.8 60.5 27.9 79.9 55.0 76.2 42.6 18.4 52.6 42.1 40.6 16.7 7.9 29.3 38.5 142.6 48.2 47.8 39.7 64.7 SNTB2 "D16S2531E, EST25263, SNT2B2, SNT3, SNTL" ENSG00000168807 "Syntrophin beta 2" Q13425 16 69187129-69309052 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 151.4;Muller glia cells: 214.1;Rod photoreceptor cells: 136.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SiHa: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001394 Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA001394: AB_1080170" "unprognostic (4.86e-1)" "unprognostic (3.26e-2)" "unprognostic (2.77e-2)" "unprognostic (8.07e-3)" "unprognostic (6.46e-2)" "unprognostic (9.68e-2)" "unprognostic (1.89e-2)" "unprognostic (5.50e-2)" "unprognostic (1.22e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-2)" "unprognostic (3.64e-2)" "unprognostic (5.77e-3)" "unprognostic (1.71e-2)" "unprognostic (7.43e-2)" "unprognostic (1.73e-2)" "unprognostic (1.88e-1)" 11.0 5.0 3.3 5.2 3.9 2.7 8.8 1.0 6.7 11.0 10.1 6.7 3.7 10.4 5.1 7.0 8.7 7.1 5.3 4.6 0.8 6.7 3.8 8.6 5.6 2.5 0.9 6.2 4.1 12.4 4.0 5.2 0.9 8.2 5.3 21.6 5.2 5.5 5.7 8.5 6.0 8.7 0.6 5.7 6.1 7.1 1.5 5.8 10.5 3.8 4.9 8.7 8.7 3.7 7.2 10.9 7.4 5.8 26.6 35.6 9.1 13.9 19.3 10.7 11.8 10.7 6.5 9.0 8.3 16.2 5.6 12.9 10.0 6.8 13.9 4.0 5.5 4.0 11.1 9.2 8.8 0.3 5.9 25.6 4.9 17.6 7.1 11.1 32.4 2.5 2.3 13.8 13.1 8.2 3.0 1.4 5.0 4.2 8.6 18.1 6.5 16.8 5.7 10.9 2.8 6.1 42.6 6.0 4.4 5.5 7.1 0.5 25.4 20.0 9.6 14.2 13.0 3.1 5.2 10.0 12.8 1.4 9.3 0.4 0.2 0.3 0.9 0.3 0.9 0.2 0.4 0.5 0.2 0.2 0.2 1.1 0.9 0.7 0.3 0.1 0.5 0.3 3.3 3.9 1.0 6.7 4.6 0.8 2.5 0.9 0.9 0.6 1.5 3.7 55.9 19.2 11.7 36.6 9.0 38.0 28.0 17.1 70.0 33.2 19.0 25.0 9.2 10.0 10.4 27.6 41.7 9.5 33.7 29.0 3.9 9.7 25.9 20.6 61.3 81.4 10.3 4.8 151.4 24.1 7.9 53.1 20.9 28.7 1.3 15.8 126.7 11.1 6.9 5.0 62.6 16.6 8.2 33.1 29.3 27.5 59.0 12.9 30.2 33.7 8.6 214.1 47.4 30.7 27.9 16.3 32.8 65.1 20.7 40.9 12.7 34.5 10.0 136.7 6.6 26.0 35.6 27.9 15.4 30.7 38.8 3.7 32.8 20.2 19.6 28.7 SNTG2 "G2SYN, SYN5" ENSG00000172554 "Syntrophin gamma 2" Q9NY99 2 950849-1367613 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 68.2;Excitatory neurons: 24.4;Horizontal cells: 90.9;Late spermatids: 44.7;Spermatocytes: 22.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HAP1: 1.7;JURKAT: 1.6;MOLT-4: 1.1;NTERA-2: 2.0;SCLC-21H: 2.0" "Low region specificity" "Detected in many" "HPA065258, HPA077904" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA065258: , HPA077904: " "unprognostic (7.52e-3)" "unprognostic (7.52e-4)" "unprognostic (4.15e-1)" "unprognostic (3.50e-2)" "unprognostic (2.52e-2)" "unprognostic (1.39e-3)" "unprognostic (2.46e-3)" "unprognostic (2.05e-1)" "unprognostic (2.23e-1)" "unprognostic (3.26e-2)" "unprognostic (7.87e-3)" "unprognostic (3.58e-3)" "unprognostic (3.64e-1)" "unprognostic (2.52e-1)" "unprognostic (1.77e-2)" "unprognostic (5.05e-2)" 2.0 0.3 0.6 0.0 0.7 0.0 1.8 1.0 0.6 1.0 1.1 0.5 0.1 1.2 0.2 0.5 1.2 0.2 0.4 1.7 0.7 0.1 0.0 0.3 0.0 1.7 0.9 0.2 0.9 0.0 2.9 0.0 1.3 0.6 0.2 2.1 0.5 0.0 0.4 1.1 0.6 0.7 0.4 3.2 0.3 1.8 0.7 0.2 0.7 0.9 0.1 0.8 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 1.0 0.6 1.7 0.7 1.7 0.9 1.3 0.4 0.7 0.6 6.8 0.0 0.0 0.7 0.4 0.9 0.1 0.0 0.6 0.8 0.2 0.3 0.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 68.2 0.1 0.9 7.3 0.0 0.0 24.4 0.2 0.5 0.8 0.0 0.0 0.0 3.0 0.0 0.0 0.1 90.9 10.7 0.0 0.0 0.0 1.2 44.7 0.3 0.0 1.8 9.4 0.0 0.6 0.0 1.5 1.3 0.0 0.0 4.1 0.0 0.3 0.0 0.5 0.0 4.6 0.0 0.3 0.4 22.0 5.4 0.1 0.1 0.0 0.2 0.2 0.0 0.2 SNX9 "SDP1, SH3PX1, SH3PXD3A" ENSG00000130340 "Sorting nexin 9" Q9Y5X1 6 157700387-157945077 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Endocytosis, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 251.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 146.6;GAMG: 145.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031410, HPA057203" Approved Supported "Plasma membrane,Cytosol" No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Cytosol "HPA031410: AB_10603339, HPA057203: AB_2683368" "unprognostic (1.63e-3)" "prognostic unfavorable (5.95e-4)" "unprognostic (1.39e-1)" "unprognostic (8.09e-2)" "unprognostic (8.09e-2)" "unprognostic (1.40e-2)" "unprognostic (4.06e-2)" "prognostic unfavorable (3.77e-4)" "unprognostic (7.93e-2)" "unprognostic (4.99e-3)" "unprognostic (4.45e-2)" "unprognostic (2.42e-1)" "prognostic favorable (9.95e-4)" "unprognostic (2.14e-1)" "unprognostic (2.46e-1)" "unprognostic (1.13e-2)" "unprognostic (2.57e-1)" 57.9 25.2 19.2 25.7 20.6 14.3 41.4 21.2 20.9 38.8 20.6 34.2 33.2 41.8 20.8 57.8 26.2 46.9 33.2 18.8 19.9 26.2 39.0 21.0 24.2 22.2 21.1 28.0 28.5 37.7 13.4 48.5 21.8 31.0 29.5 2.7 35.1 41.7 24.4 30.4 35.6 41.2 20.9 18.4 37.5 11.0 20.7 13.9 29.8 34.2 21.7 49.8 33.7 23.0 26.0 19.1 18.9 22.1 96.6 78.6 37.7 46.3 146.6 36.4 48.9 16.6 27.6 0.0 25.0 85.6 145.8 18.7 22.7 36.3 21.1 23.9 23.4 17.7 25.7 23.9 48.6 7.6 31.6 51.1 33.9 37.8 37.1 63.9 49.8 23.3 80.9 0.0 15.8 17.2 0.0 15.6 14.4 18.7 21.3 0.0 17.9 32.7 59.7 15.9 11.8 20.9 34.1 16.4 90.5 16.2 6.8 20.0 41.7 41.3 16.6 128.8 30.4 0.0 0.0 0.0 84.8 6.4 25.4 0.0 0.7 0.1 0.4 2.1 1.5 3.2 0.7 0.6 1.4 2.4 5.3 1.2 0.0 0.1 6.8 10.0 2.2 0.6 19.2 20.6 21.2 20.9 18.8 19.9 22.2 21.1 21.8 20.9 20.7 23.0 71.5 0.0 1.1 40.5 102.6 43.3 109.7 17.3 30.1 15.6 28.7 18.4 28.4 28.6 19.0 9.2 0.0 40.6 37.6 97.7 21.5 57.5 73.4 112.8 53.0 57.9 15.7 17.7 105.4 55.9 41.1 83.0 70.3 251.1 12.0 16.4 37.1 34.3 41.6 3.3 90.4 43.0 8.2 59.0 74.2 26.8 44.7 84.3 21.4 48.7 39.5 11.1 7.2 100.5 161.2 107.0 108.9 46.6 14.9 127.5 52.5 46.2 14.3 1.8 39.5 43.6 49.6 21.9 15.4 22.9 29.8 109.9 48.8 9.1 29.7 137.0 SORBS1 "CAP, FLJ12406, KIAA1296, ponsin, SH3D5, sh3p12" ENSG00000095637 "Sorbin and SH3 domain containing 1" Q9BX66 10 95311771-95561414 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 800.2;Cardiomyocytes: 612.3;Excitatory neurons: 401.1;Inhibitory neurons: 295.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 6.1" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.1" "Cell line enhanced" "Detected in many" "CACO-2: 28.0;Hep G2: 19.5;HMC-1: 48.3;SK-MEL-30: 45.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027559, CAB032850, HPA043084" Enhanced Supported "Plasma membrane,Focal adhesion sites,Centrosome" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites" "Plasma membrane, Centrosome" "CAB032850: AB_2286335, HPA027559: AB_10600812, HPA043084: AB_2678307" "prognostic favorable (2.84e-4)" "unprognostic (3.53e-1)" "unprognostic (1.89e-1)" "unprognostic (7.85e-2)" "unprognostic (3.43e-1)" "unprognostic (1.41e-1)" "unprognostic (2.98e-2)" "unprognostic (5.30e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-2)" "unprognostic (3.17e-2)" "unprognostic (1.27e-1)" "unprognostic (3.40e-2)" "unprognostic (3.13e-2)" "unprognostic (1.80e-1)" "unprognostic (2.55e-2)" "unprognostic (5.01e-3)" 370.8 21.6 128.5 53.3 153.3 4.7 78.3 101.7 144.1 46.0 42.6 312.8 25.6 169.4 32.1 155.5 99.2 81.3 351.6 127.0 165.4 17.6 49.3 34.4 3.1 164.0 161.5 19.0 22.0 26.4 11.5 30.3 126.7 140.6 67.0 39.0 24.5 217.4 190.5 24.5 62.7 151.0 138.9 8.1 143.1 14.4 127.0 3.7 14.8 155.9 1.5 235.3 47.1 139.9 1.6 1.2 12.4 3.1 4.2 0.2 2.4 0.4 0.1 0.4 0.1 28.0 10.9 0.0 2.2 0.2 4.2 0.6 2.4 0.6 0.4 3.2 4.5 7.2 0.4 19.5 1.5 0.0 48.3 0.9 0.4 0.5 0.3 0.2 4.9 1.9 11.7 2.3 1.3 0.8 0.1 0.8 5.7 6.2 2.6 1.0 4.0 0.4 15.1 18.3 4.9 3.7 1.8 0.6 45.2 8.9 2.1 0.4 0.3 0.1 4.0 0.1 2.4 1.8 0.5 0.2 4.8 0.5 11.7 6.1 0.1 1.2 0.4 0.6 0.5 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 128.5 153.3 101.7 144.1 127.0 165.4 164.0 161.5 126.7 138.9 127.0 139.9 42.2 22.4 20.9 800.2 0.8 11.6 8.7 0.0 5.2 7.5 6.5 19.3 612.3 12.8 1.3 1.8 2.1 20.2 1.0 4.0 3.9 7.2 70.4 1.4 15.8 25.7 6.0 16.0 401.1 3.1 2.4 21.4 8.6 1.6 16.4 8.2 30.4 50.5 3.1 6.7 295.1 10.9 0.0 3.8 12.0 48.6 7.5 1.1 14.2 163.9 0.7 22.1 1.0 155.3 22.6 2.3 2.8 76.8 1.1 4.7 1.2 6.1 0.1 5.5 0.0 11.8 51.6 3.4 3.7 1.9 12.5 29.6 1.6 0.1 5.1 5.9 SORT1 "Gp95, NT3" ENSG00000134243 "Sortilin 1" Q99523 1 109309568-109397918 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Osteogenesis, Transport" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 285.6" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 447.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 9.2;non-classical monocyte: 10.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006889, CAB011498" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 7170000 110000 "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB011498: AB_2192606, HPA006889: AB_1080056" "unprognostic (2.10e-2)" "unprognostic (7.46e-2)" "prognostic favorable (7.74e-6)" "unprognostic (4.12e-1)" "unprognostic (9.41e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.23e-4)" "unprognostic (3.34e-3)" "unprognostic (4.27e-2)" "unprognostic (9.44e-2)" "unprognostic (2.42e-2)" "unprognostic (1.28e-2)" "unprognostic (1.23e-3)" "unprognostic (1.45e-2)" "unprognostic (2.15e-1)" "unprognostic (3.95e-1)" "unprognostic (4.46e-3)" 48.2 11.3 71.0 12.0 168.3 21.4 25.1 124.3 114.2 17.7 21.5 29.5 22.1 24.7 139.8 41.5 27.5 17.8 64.7 131.8 90.0 38.7 6.5 37.4 2.8 151.9 133.8 6.1 17.5 46.5 11.3 44.8 153.1 18.3 26.9 40.0 25.2 44.0 85.0 19.0 21.9 27.8 102.8 10.2 18.2 43.5 118.0 6.4 42.7 71.8 10.3 16.9 18.0 285.6 38.8 15.3 37.5 45.8 107.0 21.2 107.3 28.2 44.9 27.2 29.0 39.8 14.0 0.3 35.2 11.9 19.9 9.4 44.7 22.3 38.9 1.1 21.2 10.7 23.5 43.1 41.8 0.2 33.5 53.2 3.6 33.3 7.3 72.6 4.2 31.7 81.3 4.0 38.7 41.1 27.9 0.8 14.1 17.5 6.3 30.7 87.9 18.9 52.0 27.8 38.3 21.8 16.6 109.3 120.6 53.1 46.1 6.7 1.1 5.8 21.7 1.0 47.6 37.0 32.2 0.3 9.8 0.3 24.3 0.0 7.1 2.5 0.0 9.2 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 1.8 0.4 10.8 1.6 0.0 2.0 71.0 168.3 124.3 114.2 131.8 90.0 151.9 133.8 153.1 102.8 118.0 285.6 10.6 38.5 47.9 54.5 1.9 1.3 4.7 6.7 1.2 14.9 27.5 14.2 98.9 27.1 20.3 75.4 35.5 30.6 3.2 70.2 5.9 23.9 65.1 33.2 5.2 15.9 16.8 4.0 87.9 23.7 30.2 9.8 16.8 34.9 7.6 10.4 7.9 22.1 30.1 13.5 56.7 27.7 6.1 38.7 9.9 79.7 8.7 34.6 21.4 78.7 37.7 21.7 0.0 48.7 447.8 25.6 23.2 49.7 1.5 7.1 64.0 13.1 29.6 50.7 32.9 25.1 53.6 46.3 21.6 9.3 1.8 36.8 2.1 1.8 28.3 10.8 SPG11 "ALS5, FLJ21439, KIAA1840" ENSG00000104133 "SPG11 vesicle trafficking associated, spatacsin" Q96JI7 15 44562696-44663678 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040412, HPA040947" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" Nucleoli "HPA040412: AB_10795418, HPA040947: AB_10796232" "unprognostic (1.10e-1)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (1.98e-3)" "unprognostic (1.99e-1)" "unprognostic (9.31e-2)" "unprognostic (2.91e-1)" "unprognostic (2.32e-1)" "unprognostic (6.71e-2)" "unprognostic (2.26e-3)" "unprognostic (2.58e-2)" "unprognostic (9.19e-2)" "prognostic favorable (6.28e-5)" "unprognostic (8.73e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.06e-2)" 21.1 27.1 18.4 18.2 25.7 27.4 21.6 24.4 21.3 21.5 23.9 25.6 17.1 17.9 25.3 25.6 20.2 16.1 25.5 17.5 22.2 25.0 29.8 24.8 28.4 23.8 22.1 21.4 28.6 26.7 21.3 14.9 23.9 25.3 19.9 30.5 24.7 15.0 22.9 30.4 30.1 12.7 19.1 43.0 26.0 25.5 24.6 23.7 30.9 14.3 18.6 23.8 22.6 33.4 13.2 8.8 21.9 21.6 33.7 33.0 15.8 13.4 17.4 13.0 16.6 10.8 12.5 9.7 16.5 18.2 22.5 29.0 15.1 20.8 12.5 29.3 9.0 22.1 21.1 16.4 23.7 22.2 19.2 25.3 23.3 10.7 30.5 20.4 18.6 16.6 28.8 24.2 18.6 11.5 10.1 19.7 11.5 40.3 11.6 12.9 18.5 10.6 28.0 33.6 14.2 16.8 14.6 23.3 13.1 18.0 22.0 30.2 19.9 17.1 8.5 21.4 16.5 23.8 22.6 19.2 17.6 28.8 17.9 5.7 7.7 11.8 6.5 9.2 6.9 10.0 5.4 4.9 6.2 11.3 4.3 5.3 11.6 6.2 12.4 6.3 6.1 3.7 18.4 25.7 24.4 21.3 17.5 22.2 23.8 22.1 23.9 19.1 24.6 33.4 21.0 44.8 22.2 56.2 40.4 9.3 15.6 18.8 14.2 25.1 19.0 12.6 20.1 18.6 31.3 27.6 47.9 16.5 30.1 29.3 5.9 21.3 28.2 31.7 23.2 17.6 20.0 22.3 62.9 16.9 10.1 19.3 37.2 33.6 27.3 31.9 21.8 23.5 20.1 16.8 68.1 31.2 26.4 43.3 23.5 33.2 17.7 40.4 14.2 74.9 88.1 14.0 50.4 68.3 121.4 17.7 24.0 13.9 21.4 19.3 30.8 14.9 53.6 21.7 6.6 24.8 16.3 51.7 31.6 20.1 11.1 9.3 29.5 24.4 27.3 22.2 SPHK1 SPHK ENSG00000176170 "Sphingosine kinase 1" Q9NYA1 17 76376584-76387860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 105.4;Muller glia cells: 165.1;Pancreatic endocrine cells: 101.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 127.6;TIME: 108.9;U-251 MG: 142.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "olfactory bulb: 5.7" "HPA022829, HPA028761" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Cytosol" "HPA022829: AB_1857438, HPA028761: AB_10600814" "unprognostic (1.04e-1)" "unprognostic (6.30e-2)" "unprognostic (1.09e-2)" "unprognostic (8.66e-2)" "unprognostic (2.25e-2)" "unprognostic (1.82e-1)" "unprognostic (1.68e-2)" "unprognostic (9.32e-3)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (8.99e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.14e-6)" "unprognostic (1.39e-1)" "unprognostic (4.82e-2)" "unprognostic (8.29e-2)" "unprognostic (1.10e-3)" 18.9 4.1 4.0 10.5 3.0 17.3 18.0 2.1 3.9 11.0 2.3 7.0 1.9 6.7 3.9 23.8 9.4 11.9 17.5 2.9 3.9 21.4 3.8 24.3 8.1 4.0 4.1 4.3 14.4 4.8 4.9 2.5 4.5 7.3 1.1 8.4 19.9 1.5 3.2 15.6 7.0 3.2 2.3 5.0 6.7 5.8 8.5 3.5 10.6 0.8 4.1 11.3 13.1 3.9 36.9 3.7 15.2 0.8 7.6 7.0 15.8 82.6 54.0 67.8 40.8 19.4 3.9 1.8 7.4 61.0 28.9 7.7 11.7 105.4 16.4 1.6 6.2 0.5 28.3 127.6 16.6 1.3 2.9 13.6 2.1 105.9 41.3 28.8 66.0 3.7 17.3 0.2 13.5 46.6 3.5 0.6 0.9 8.2 29.7 2.5 4.1 2.8 3.7 0.5 2.0 3.6 8.3 0.9 74.4 9.1 3.0 5.1 108.9 105.8 20.8 82.3 142.1 1.7 0.4 1.6 80.5 6.5 16.1 1.5 1.9 0.0 0.7 0.9 0.2 0.0 0.1 0.2 0.5 0.1 0.0 0.1 0.2 0.0 0.2 4.8 0.0 0.8 4.0 3.0 2.1 3.9 2.9 3.9 4.0 4.1 4.5 2.3 8.5 3.9 22.0 0.0 0.0 1.0 2.8 12.6 57.0 18.6 2.8 1.5 31.1 29.1 5.3 47.1 6.6 1.8 0.0 1.2 9.1 1.0 0.0 105.4 0.2 15.3 13.5 51.2 0.0 22.3 0.5 12.7 16.9 27.5 3.1 60.7 7.0 0.4 4.2 0.2 30.1 33.7 1.6 2.4 6.1 8.9 45.4 1.4 3.7 39.9 12.4 1.0 61.5 165.1 3.1 0.0 0.1 101.8 1.2 19.9 3.5 68.9 0.8 2.5 2.0 3.9 0.0 17.3 54.3 0.0 9.5 6.7 10.7 1.4 4.2 0.8 0.4 27.0 SPINT1 "HAI, MANSC2" ENSG00000166145 "Serine peptidase inhibitor, Kunitz type 1" O43278 15 40844018-40858207 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 255.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1254.0;Distal enterocytes: 477.6;Proximal enterocytes: 514.5;Syncytiotrophoblasts: 1673.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 323.2;HaCaT: 377.6;hTCEpi: 264.0;RT4: 308.2;SK-BR-3: 558.8;T-47d: 267.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006903, HPA031178" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 7400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA006903: AB_1079038, HPA031178: AB_2732463" "prognostic unfavorable (6.97e-4)" "unprognostic (1.00e-3)" "unprognostic (3.00e-3)" "unprognostic (5.03e-2)" "unprognostic (6.06e-2)" "unprognostic (3.19e-1)" "unprognostic (5.94e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-3)" "unprognostic (1.46e-2)" "unprognostic (1.09e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.37e-7)" "unprognostic (5.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.45e-3)" "unprognostic (2.17e-2)" 2.8 0.7 0.9 16.4 1.5 1.4 34.7 5.0 1.3 42.8 6.4 108.7 159.9 13.2 78.9 255.5 33.6 38.0 1.3 0.9 2.0 79.9 3.5 47.6 6.4 2.8 3.2 2.4 69.2 132.9 31.4 144.9 2.2 52.3 89.2 0.4 162.7 31.4 0.6 148.9 138.2 4.3 1.7 6.9 88.3 1.8 3.2 9.9 34.7 0.4 45.5 57.1 90.1 2.3 124.8 1.0 0.0 0.9 0.1 0.0 323.2 2.3 3.0 4.0 2.4 195.3 202.4 0.3 141.2 0.4 3.6 377.6 30.8 181.9 2.4 1.0 10.6 5.6 3.3 10.8 2.2 21.9 93.9 0.3 264.0 3.9 16.5 3.4 14.7 12.1 2.7 1.1 0.2 96.5 0.9 16.6 37.4 207.6 17.7 12.6 0.0 24.9 179.3 308.2 79.8 3.9 9.3 558.8 15.7 56.9 267.7 16.1 0.0 0.2 2.0 1.2 0.5 1.2 24.5 0.8 0.8 16.3 1.1 0.0 19.7 14.3 0.4 15.9 0.8 8.4 3.0 1.4 32.4 6.0 1.1 0.3 25.9 5.5 18.1 4.0 0.5 7.6 0.9 1.5 5.0 1.3 0.9 2.0 2.8 3.2 2.2 1.7 3.2 2.3 0.8 57.7 14.7 0.0 7.6 76.0 96.7 220.0 55.8 0.1 96.2 63.5 0.5 105.8 207.3 134.3 0.0 1254.0 1.4 477.6 25.4 429.4 0.8 63.3 14.2 6.9 147.3 4.8 0.5 255.1 105.1 10.4 106.5 155.6 10.2 1.9 0.4 0.5 135.4 0.0 0.5 169.4 221.8 10.0 23.8 1.1 3.7 19.8 14.2 0.0 68.6 0.0 0.0 0.0 0.0 309.8 375.2 0.0 2.1 135.7 514.5 44.2 46.6 0.3 0.0 0.1 12.6 0.6 5.9 93.2 87.9 1673.8 6.6 0.1 182.7 222.3 SPPL2B "IMP4, KIAA1532, PSL1" ENSG00000005206 "Signal peptide peptidase like 2B" Q8TCT7 19 2328615-2355095 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 109.1;Late spermatids: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005592, HPA039292" Approved Approved "Nucleoplasm,Plasma membrane,Centrosome" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" Centrosome "CAB005592: AB_325074, HPA039292: AB_2676429" "unprognostic (4.16e-2)" "unprognostic (2.97e-2)" "unprognostic (2.48e-2)" "prognostic favorable (5.00e-5)" "unprognostic (2.34e-1)" "unprognostic (1.54e-3)" "unprognostic (1.74e-1)" "unprognostic (7.93e-3)" "unprognostic (3.00e-1)" "unprognostic (1.72e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.29e-3)" "prognostic unfavorable (6.45e-4)" "unprognostic (2.26e-2)" "unprognostic (2.45e-1)" "unprognostic (3.02e-1)" "unprognostic (3.40e-2)" 23.1 23.2 13.7 16.7 13.6 29.1 27.4 15.5 18.6 28.4 17.4 43.4 41.6 26.4 4.4 22.5 34.0 10.7 21.6 11.8 12.1 35.9 33.0 22.2 20.7 19.2 15.6 27.2 50.7 11.0 63.8 10.4 15.5 32.5 9.2 7.1 27.2 9.8 25.3 28.9 52.6 5.9 13.2 39.1 33.9 63.5 15.1 12.0 40.5 3.1 9.9 21.9 20.9 16.4 16.6 25.9 10.9 19.5 8.8 8.9 27.8 21.1 6.1 7.6 8.1 18.2 18.4 15.7 19.4 9.9 7.1 21.7 3.6 7.3 2.3 18.4 16.0 10.4 44.7 24.9 16.5 18.6 13.1 13.1 8.2 7.2 5.2 11.9 10.7 32.2 17.3 39.0 4.7 18.4 20.2 23.6 20.4 14.7 10.5 33.4 5.8 43.9 8.3 41.0 19.4 18.3 21.2 12.8 16.7 7.1 21.3 30.8 24.3 13.8 9.7 35.3 16.9 51.0 20.1 16.7 17.3 21.4 24.5 11.5 7.7 7.4 6.2 7.7 4.4 8.2 5.6 6.0 9.4 12.5 6.9 7.7 3.3 6.4 5.4 17.0 6.0 6.4 13.7 13.6 15.5 18.6 11.8 12.1 19.2 15.6 15.5 13.2 15.1 16.4 23.6 3.2 17.2 57.1 30.8 0.0 6.5 0.0 8.0 26.1 21.6 21.5 6.0 20.0 5.0 25.8 47.9 50.6 18.8 79.5 1.9 16.6 51.4 39.3 22.2 14.4 40.7 14.5 25.3 11.5 20.8 14.2 109.1 25.5 7.0 39.9 13.2 15.1 11.8 32.0 30.3 63.2 0.0 9.4 0.0 107.7 14.9 10.8 0.0 9.4 8.0 13.2 19.6 39.7 35.2 10.4 49.9 15.8 11.5 7.3 57.8 7.9 10.9 39.4 0.0 15.0 11.7 57.0 13.5 10.8 0.0 42.8 11.0 36.4 49.8 6.0 SPPL3 "DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4" ENSG00000157837 "Signal peptide peptidase like 3" Q8TCT6 12 120762510-120904358 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004194, HPA059958" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Plasma membrane" "HPA004194: AB_2667171, HPA059958: AB_2684179" "unprognostic (3.29e-1)" "unprognostic (2.29e-2)" "unprognostic (3.39e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-1)" "unprognostic (7.96e-3)" "prognostic unfavorable (1.29e-5)" "unprognostic (3.17e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.48e-1)" "unprognostic (2.44e-1)" "unprognostic (2.66e-1)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (7.54e-2)" "unprognostic (9.40e-2)" 20.9 14.9 25.3 11.9 28.1 20.9 24.2 29.0 27.5 30.0 13.1 26.7 18.2 26.3 15.7 44.3 28.6 18.7 18.1 25.4 30.6 22.8 19.3 20.4 15.9 25.0 26.0 31.4 21.3 49.6 13.9 28.4 26.1 20.6 27.2 15.5 20.2 27.0 15.7 56.5 18.8 29.6 24.1 24.3 15.2 39.0 26.4 32.7 31.2 19.6 27.8 28.6 34.2 31.4 30.0 29.2 43.4 27.4 56.2 37.7 30.5 22.5 66.6 47.4 37.9 30.5 29.9 27.4 0.1 39.4 42.0 35.6 44.8 48.4 48.9 21.9 27.5 23.6 16.2 23.4 59.2 27.4 29.3 38.1 75.9 40.7 38.1 56.0 47.1 41.5 26.5 13.4 41.2 26.3 36.7 22.0 29.2 27.8 20.6 21.6 36.6 19.7 36.8 83.8 29.7 31.9 42.8 19.6 34.7 46.1 58.9 18.7 35.4 21.9 29.5 13.6 17.1 30.9 60.3 26.4 32.5 22.3 36.9 4.8 1.2 1.1 1.3 1.2 1.8 1.3 1.6 1.7 2.1 1.6 1.5 1.7 2.2 1.3 1.1 2.7 1.4 0.7 25.3 28.1 29.0 27.5 25.4 30.6 25.0 26.0 26.1 24.1 26.4 31.4 35.2 19.2 20.8 79.3 25.3 55.1 32.3 29.4 43.3 37.8 35.2 24.1 21.2 20.0 19.8 40.5 27.1 42.0 21.2 47.2 1.9 19.3 8.6 20.9 26.9 33.0 27.1 14.5 97.2 24.7 29.0 33.2 25.0 29.7 4.5 68.7 37.5 33.1 38.3 37.0 112.6 33.7 22.4 38.1 39.3 8.0 28.6 34.5 26.6 79.6 26.6 23.0 16.5 141.3 192.3 22.8 34.9 35.0 22.0 33.4 34.0 18.1 18.1 22.4 13.1 32.3 27.4 55.6 41.1 76.9 84.7 64.6 22.4 35.0 35.4 37.6 SRC "ASV, c-src, SRC1" ENSG00000197122 "SRC proto-oncogene, non-receptor tyrosine kinase" P12931 20 37344685-37406050 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell adhesion, Cell cycle, Host-virus interaction, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 42.0;Gastric mucus-secreting cells: 43.8;Langerhans cells: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 6 "dendritic cells: 1.4;monocytes: 2.4" "Cell line enhanced" "Detected in many" "A549: 110.8;HBEC3-KT: 102.6;RT4: 106.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004023, HPA030875" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" NA NA 3200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 15: RT4 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cell Junctions" "Nucleoplasm, Cytosol" "CAB004023: AB_2106059, HPA030875: AB_2673640" "unprognostic (5.58e-2)" "unprognostic (9.83e-2)" "unprognostic (3.56e-1)" "unprognostic (4.54e-3)" "unprognostic (1.52e-1)" "unprognostic (1.54e-2)" "prognostic unfavorable (4.90e-5)" "unprognostic (3.89e-2)" "unprognostic (7.04e-2)" "unprognostic (8.13e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.63e-4)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.33e-2)" "unprognostic (4.72e-2)" "unprognostic (3.65e-2)" "prognostic favorable (5.22e-5)" 9.7 25.3 5.7 13.3 5.2 8.4 10.1 0.4 6.2 25.1 1.5 30.3 39.8 31.9 3.2 26.1 23.8 27.9 8.8 6.4 5.5 21.4 4.3 16.1 6.3 2.6 3.4 23.6 30.8 11.1 15.9 8.1 2.2 30.8 17.1 5.5 11.8 27.4 2.4 13.0 38.8 17.2 1.7 14.2 39.9 25.2 5.0 6.1 9.8 1.5 8.1 35.6 24.6 3.0 24.6 110.8 24.9 22.6 9.3 14.7 51.6 22.0 18.9 26.3 16.6 41.9 21.5 0.7 13.4 40.2 29.9 43.5 15.1 102.6 10.3 0.1 13.7 6.2 3.9 65.9 22.0 0.3 9.3 15.7 34.2 17.3 22.8 29.4 24.3 14.2 0.6 0.2 4.4 16.7 6.0 0.8 11.7 67.3 98.8 26.5 6.6 0.7 11.0 106.3 23.1 83.6 25.0 34.5 27.2 19.1 31.1 9.0 35.8 31.4 20.9 11.7 20.1 0.3 0.8 0.3 22.1 0.1 24.0 0.0 1.6 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 2.3 1.4 0.0 1.0 5.7 5.2 0.4 6.2 6.4 5.5 2.6 3.4 2.2 1.7 5.0 3.0 1.0 3.2 1.7 3.3 4.1 8.2 12.5 9.5 10.8 6.5 6.2 7.5 2.2 18.6 4.7 12.9 2.1 2.3 4.9 42.0 1.9 12.2 1.8 6.4 10.7 1.4 16.8 0.4 9.5 18.7 8.3 7.2 43.8 12.4 0.0 14.8 1.1 1.6 5.7 3.3 9.1 29.2 8.2 9.4 46.3 3.3 10.8 22.8 1.8 9.4 9.7 4.4 1.0 9.0 0.6 39.1 19.2 17.3 4.3 18.0 36.7 9.3 5.6 5.2 13.1 1.8 6.7 0.3 1.1 11.2 9.1 2.3 1.0 2.9 16.9 36.6 SSTR5 ENSG00000162009 "Somatostatin receptor 5" P35346 16 1078781-1080142 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 6.9;kidney: 2.9;pituitary gland: 7.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hypothalamus: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "Hep G2: 15.4;PC-3: 54.7" "Group enriched" "Detected in some" 5 "basal ganglia: 4.1;hypothalamus: 2.3" "Low region specificity" "Detected in many" HPA066503 Supported "Plasma membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "HPA066503: AB_2685679" "unprognostic (2.16e-2)" "unprognostic (7.31e-2)" "unprognostic (3.69e-2)" "unprognostic (2.39e-2)" "unprognostic (2.14e-1)" "unprognostic (9.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.72e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-1)" "unprognostic (4.09e-2)" 0.0 2.5 0.1 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 6.9 0.3 1.5 2.9 0.0 0.0 0.0 0.2 0.3 0.0 0.3 0.0 7.3 0.0 0.1 0.7 0.0 0.2 1.0 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.4 0.0 0.2 0.2 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 54.7 0.0 2.1 0.6 0.0 2.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.3 1.5 0.2 0.3 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 STAMBP AMSH ENSG00000124356 "STAM binding protein" O95630 2 73828916-73873659 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 12 "LHCN-M2: 1108.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035800, HPA035801" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 18000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA035800: AB_10670591, HPA035801: AB_2732470" "unprognostic (1.86e-2)" "unprognostic (1.14e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (4.70e-5)" "unprognostic (6.13e-2)" "unprognostic (2.08e-3)" "unprognostic (3.73e-2)" "unprognostic (1.71e-1)" "unprognostic (6.58e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (1.01e-1)" "unprognostic (2.29e-1)" "unprognostic (7.72e-2)" "unprognostic (2.63e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" 15.6 11.6 21.7 14.6 30.6 13.3 20.2 29.7 23.8 19.3 19.3 21.5 20.7 20.6 15.5 25.4 18.3 16.9 22.3 20.6 24.5 21.9 19.0 15.7 19.3 31.3 28.0 17.7 12.2 24.3 9.3 17.3 30.4 22.1 23.2 14.6 21.5 15.6 37.4 16.7 20.4 21.3 27.9 14.9 18.2 15.8 27.1 23.2 22.6 42.8 21.6 16.8 16.0 38.6 39.0 44.0 34.0 31.6 31.1 37.2 39.1 23.3 31.7 42.1 40.3 73.7 35.9 32.2 35.8 19.8 55.7 30.0 36.6 81.7 47.6 56.6 41.3 43.3 29.1 58.1 43.4 35.8 50.0 30.1 57.6 49.6 70.7 53.5 25.1 43.7 47.9 47.8 1108.9 46.8 55.9 32.4 54.9 55.1 22.7 38.6 89.4 46.1 45.2 43.0 62.0 45.8 28.4 34.6 49.1 36.4 32.3 21.4 22.0 37.5 44.5 22.9 41.9 44.8 46.9 24.9 46.4 38.1 44.7 30.7 18.9 34.2 15.9 21.4 17.2 21.5 18.3 15.6 19.9 19.3 18.9 14.4 27.6 22.3 19.9 19.5 25.8 14.9 21.7 30.6 29.7 23.8 20.6 24.5 31.3 28.0 30.4 27.9 27.1 38.6 22.1 19.2 17.7 22.9 21.5 16.3 28.9 61.7 31.3 22.3 28.8 27.7 41.1 28.6 34.4 25.8 12.5 43.0 27.4 48.7 49.0 37.9 80.8 35.6 37.3 21.4 10.3 34.9 18.5 36.3 32.5 26.0 18.8 45.8 52.6 21.2 17.5 41.1 33.0 26.9 22.1 36.4 40.7 27.7 16.2 125.0 32.6 25.2 7.2 16.9 34.1 24.9 25.7 26.2 67.2 44.5 41.8 34.6 21.5 40.9 57.2 68.8 24.5 21.0 39.5 28.2 27.2 33.1 44.2 44.5 21.6 44.5 21.4 27.5 34.3 27.1 STEAP4 "FLJ23153, SchLAH, STAMP2, TIARP, TNFAIP9" ENSG00000127954 "STEAP4 metalloreductase" Q687X5 7 88270892-88306894 "Enzymes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 113.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 402.5;Club cells: 152.8;Sertoli cells: 460.2;Smooth muscle cells: 255.3" "Cancer enhanced" "Detected in many" "prostate cancer: 45.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 12 "neutrophil: 163.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 163.6" "Group enriched" "Detected in some" 6 "HSkMC: 122.1;SiHa: 119.7;U-2197: 166.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA065201 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Plasma membrane" "HPA065201: " "unprognostic (3.76e-2)" "unprognostic (2.16e-2)" "unprognostic (8.82e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.96e-2)" "prognostic favorable (2.97e-4)" "unprognostic (7.40e-2)" "unprognostic (3.12e-1)" "unprognostic (4.66e-2)" "unprognostic (4.21e-1)" "unprognostic (2.98e-1)" "unprognostic (7.51e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (1.72e-1)" "unprognostic (2.00e-1)" "unprognostic (4.53e-2)" 113.7 46.3 1.0 31.7 0.9 7.1 68.6 2.8 1.5 21.3 17.0 13.3 3.8 17.9 7.8 15.4 36.1 22.7 24.1 1.4 1.0 11.8 24.3 67.5 7.2 1.2 0.9 4.4 10.6 16.0 13.0 15.3 0.8 60.0 9.2 1.9 26.8 10.6 13.4 19.3 10.6 29.3 0.4 5.4 10.6 13.4 1.1 7.8 53.1 16.6 5.1 34.3 22.7 1.1 4.9 0.0 0.1 0.1 0.1 1.9 0.3 0.0 0.3 0.0 0.1 0.1 23.6 0.1 0.1 0.0 0.4 18.7 0.1 0.0 0.1 0.0 0.1 0.1 7.9 0.1 0.1 0.1 0.2 122.1 0.1 0.4 0.9 0.0 0.0 0.1 0.3 0.4 0.0 3.0 0.1 0.5 0.1 1.0 0.0 0.2 0.1 0.3 0.0 0.3 0.2 0.2 119.7 9.9 0.0 0.1 0.8 0.0 0.1 0.4 0.3 166.4 0.1 0.1 0.1 0.1 0.2 0.9 0.2 0.4 13.5 1.4 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 163.6 0.2 0.1 0.3 0.0 3.2 1.0 0.9 2.8 1.5 1.4 1.0 1.2 0.9 0.8 0.4 1.1 1.1 77.2 54.5 402.5 0.0 0.8 9.4 5.8 8.6 1.8 1.8 21.6 8.3 9.1 0.0 152.8 0.0 2.1 0.4 1.1 0.4 0.0 14.6 23.8 14.6 20.5 14.7 0.0 0.0 0.5 9.6 10.6 39.8 1.1 51.2 16.4 0.0 15.4 0.7 2.8 0.0 0.8 0.2 16.2 7.2 7.4 10.9 114.9 12.2 5.4 6.5 19.0 2.7 0.0 1.0 0.1 18.6 0.0 9.1 0.2 49.3 0.1 0.1 72.8 0.3 460.2 9.6 255.3 0.9 0.3 1.5 18.8 10.9 3.1 57.7 0.2 16.6 STOML2 "HSPC108, SLP-2" ENSG00000165283 "Stomatin like 2" Q9UJZ1 9 35099776-35103195 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015944, HPA062016" Supported Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 44000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "CAB015944: , HPA062016: AB_2684659" "unprognostic (2.49e-1)" "unprognostic (2.69e-1)" "unprognostic (1.20e-2)" "unprognostic (9.43e-2)" "unprognostic (1.29e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (4.77e-4)" "unprognostic (5.14e-2)" "unprognostic (4.25e-2)" "unprognostic (1.04e-2)" "unprognostic (9.06e-2)" "unprognostic (1.45e-1)" "prognostic favorable (3.00e-5)" "unprognostic (2.74e-2)" "unprognostic (5.26e-1)" "unprognostic (2.67e-1)" "unprognostic (5.47e-2)" 63.6 93.3 45.4 39.1 46.2 66.7 62.0 47.5 49.0 58.4 61.3 75.3 55.6 64.2 49.4 84.7 57.3 33.2 123.4 46.2 46.6 75.4 99.2 43.7 46.6 44.7 45.9 59.4 69.5 71.9 42.3 46.2 45.3 49.0 67.2 23.5 59.3 48.4 171.2 71.0 61.2 54.0 45.9 53.1 75.8 42.8 48.2 55.1 48.6 111.7 59.5 64.5 56.5 45.4 219.6 248.1 130.3 195.7 93.3 111.1 139.5 105.9 153.5 292.6 212.5 283.2 99.6 183.2 72.9 135.2 210.6 91.4 201.3 235.8 193.7 158.1 185.0 112.7 202.6 269.7 272.1 215.8 124.0 141.9 181.1 238.6 283.2 92.2 193.8 183.6 186.5 109.1 144.8 176.0 193.5 377.6 205.3 162.4 155.2 166.6 110.3 197.0 159.5 128.9 120.4 146.3 60.0 158.0 141.7 92.5 109.7 139.1 106.2 99.7 141.1 84.4 190.4 76.1 140.3 173.8 132.7 134.3 137.1 67.8 73.0 42.5 64.7 65.8 77.8 91.4 73.1 74.1 98.0 87.0 69.2 63.8 12.9 98.1 49.3 121.8 115.5 114.4 45.4 46.2 47.5 49.0 46.2 46.6 44.7 45.9 45.3 45.9 48.2 45.4 63.9 41.7 33.1 6.5 66.8 96.4 123.8 172.9 83.6 36.6 104.5 118.7 83.4 108.7 92.5 49.7 8.4 233.6 48.3 116.1 250.5 144.3 77.2 72.7 76.3 66.4 98.8 106.2 7.8 153.4 245.2 74.9 66.3 47.3 84.3 111.3 61.4 111.3 132.7 18.5 8.1 145.9 73.2 41.0 68.3 22.9 75.2 47.9 99.6 5.6 84.5 83.9 56.7 2.5 8.8 137.2 117.5 69.6 126.1 177.6 197.7 290.1 85.8 37.1 52.6 66.5 95.6 73.1 110.0 119.2 114.5 166.4 51.2 153.2 222.2 148.7 STOML3 "Epb7.2l, SRO" ENSG00000133115 "Stomatin like 3" Q8TAV4 13 38965925-38990859 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "fallopian tube: 34.9" "Group enriched" "Detected in some" 19 "Endometrial ciliated cells: 75.5;Respiratory ciliated cells: 109.2" "Group enriched" "Detected in some" 4 "endometrial cancer: 2.4;lung cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 40 "AF22: 17.5" "Region enriched" "Detected in many" 6 "olfactory bulb: 23.6" "HPA012892, HPA071011" Enhanced Supported "Plasma membrane" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "HPA012892: AB_1857610, HPA071011: AB_2732169" "unprognostic (2.64e-1)" "unprognostic (1.91e-2)" "prognostic favorable (1.49e-4)" "unprognostic (1.82e-1)" "unprognostic (1.17e-1)" "unprognostic (4.24e-2)" "unprognostic (1.19e-1)" "unprognostic (2.14e-1)" "unprognostic (2.14e-1)" "unprognostic (1.07e-2)" "unprognostic (1.35e-2)" "unprognostic (3.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.22e-1)" 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.5 0.0 0.7 1.3 0.1 0.0 0.6 0.0 0.0 34.9 0.0 0.0 1.1 1.8 0.0 0.0 2.1 0.0 4.7 5.1 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.5 0.0 1.1 1.8 4.7 5.1 5.0 2.0 0.9 1.3 0.0 0.0 1.5 0.0 0.0 0.1 0.1 2.6 0.0 0.0 0.0 0.4 0.1 0.0 4.8 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.4 75.5 0.4 0.3 0.0 0.0 0.1 0.0 1.1 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.0 0.0 0.0 1.5 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 109.2 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.1 STX18 Ufe1 ENSG00000168818 "Syntaxin 18" Q9P2W9 4 4415742-4542346 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 119.9" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 191.1;Glandular and luminal cells: 249.4" "Cancer enriched" "Detected in all" 5 "endometrial cancer: 43.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003019 Approved Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum, Plasma membrane" "HPA003019: AB_1857622" "unprognostic (2.33e-1)" "unprognostic (1.65e-1)" "prognostic favorable (2.84e-4)" "prognostic favorable (6.33e-8)" "unprognostic (4.21e-1)" "unprognostic (6.77e-2)" "unprognostic (6.17e-3)" "unprognostic (2.95e-2)" "unprognostic (7.53e-2)" "unprognostic (3.22e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-2)" "prognostic favorable (7.03e-4)" "unprognostic (1.92e-2)" "unprognostic (1.55e-1)" "unprognostic (7.44e-2)" "prognostic favorable (4.69e-4)" 10.6 16.0 8.4 10.9 9.4 12.0 10.9 8.9 10.4 119.9 14.5 12.8 18.1 53.9 8.2 10.7 48.6 14.0 13.0 7.9 9.9 29.2 15.7 10.8 13.2 9.4 8.9 11.3 22.5 16.9 14.6 12.8 10.1 10.6 13.4 8.3 12.1 8.9 16.5 12.0 15.6 15.7 8.2 10.6 18.5 30.5 10.2 9.4 11.3 9.9 12.4 11.0 11.8 9.3 26.6 16.7 19.3 20.0 16.2 23.7 26.1 30.1 26.9 27.6 22.8 35.5 37.3 35.1 69.7 27.1 24.9 13.9 34.6 17.2 27.0 15.1 18.6 22.0 22.3 43.4 24.2 38.6 17.8 22.2 14.7 23.4 16.9 15.4 23.5 27.5 21.7 30.0 19.9 14.0 35.6 27.2 26.0 21.3 36.1 31.4 14.6 28.2 28.2 15.6 24.7 22.0 22.2 14.7 26.4 16.5 21.6 18.3 27.2 16.7 18.4 15.4 32.1 21.6 35.4 40.1 20.4 29.3 21.0 10.6 15.6 10.8 15.1 16.0 18.2 16.7 14.0 13.7 23.8 14.4 11.7 13.4 3.1 16.9 20.6 37.6 14.3 14.0 8.4 9.4 8.9 10.4 7.9 9.9 9.4 8.9 10.1 8.2 10.2 9.3 17.5 32.1 9.0 52.5 15.8 7.9 8.3 20.3 9.6 39.3 14.4 11.6 20.4 18.6 25.3 20.2 20.9 31.0 27.9 33.8 70.5 32.5 80.6 191.1 38.4 14.8 4.9 15.6 40.2 27.9 19.0 18.5 23.9 249.4 8.2 21.6 6.8 10.8 28.1 10.1 48.0 22.8 32.6 13.7 12.4 76.5 14.0 21.3 14.2 48.7 26.5 25.8 16.5 37.7 56.4 36.5 28.8 14.7 20.4 15.7 32.8 25.2 34.5 17.7 6.6 13.1 18.1 94.9 35.7 13.1 9.7 31.7 18.9 27.2 20.0 13.9 SVIL ENSG00000197321 Supervillin O95425 10 29457338-29736959 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 808.1;tongue: 581.5" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 204.9;Cardiomyocytes: 469.6;Peritubular cells: 260.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 259.3" "Lineage enriched" "Detected in all" 9 "granulocytes: 259.3" "Cell line enhanced" "Detected in many" "HaCaT: 146.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010878, HPA020095, HPA020138" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 210000 "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Actin filaments, Cytosol" "CAB010878: AB_476685, HPA020095: AB_1857680, HPA020138: AB_1857681" "unprognostic (1.11e-1)" "unprognostic (2.94e-1)" "unprognostic (8.06e-2)" "unprognostic (1.15e-2)" "unprognostic (3.47e-3)" "unprognostic (2.26e-2)" "unprognostic (4.12e-1)" "unprognostic (1.49e-1)" "unprognostic (4.28e-1)" "unprognostic (3.42e-3)" "unprognostic (1.55e-1)" "unprognostic (9.20e-2)" "unprognostic (2.38e-3)" "unprognostic (7.11e-3)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (5.70e-5)" 26.4 13.4 3.7 22.7 3.9 37.2 22.6 1.3 8.9 45.8 2.5 314.5 14.8 116.2 24.1 92.1 55.5 52.0 165.0 2.2 2.7 15.4 10.4 22.9 12.6 7.0 4.1 83.3 18.5 31.8 8.5 17.9 4.4 70.3 37.1 10.3 40.6 100.0 808.1 26.9 60.1 107.0 4.4 7.6 77.6 11.7 4.9 19.1 35.0 581.5 10.8 173.2 40.3 5.2 71.4 27.9 12.4 5.4 32.1 84.4 22.1 12.6 24.1 4.3 4.7 34.4 63.1 2.4 43.0 4.9 31.9 146.8 8.6 25.6 5.2 1.4 17.6 0.1 33.6 19.9 21.4 8.0 1.5 72.7 24.5 44.2 19.1 71.9 69.6 14.7 0.1 0.4 6.7 19.9 7.7 4.0 7.0 27.8 15.1 15.5 32.1 0.9 40.2 20.1 18.1 14.1 12.3 1.4 34.3 39.8 12.9 7.9 46.3 21.9 23.4 94.4 34.4 0.6 0.8 0.3 64.5 14.0 65.4 43.4 12.1 58.2 11.1 14.0 10.9 0.6 11.2 7.6 7.3 1.0 17.1 10.9 259.3 14.6 29.6 3.0 4.3 3.7 3.7 3.9 1.3 8.9 2.2 2.7 7.0 4.1 4.4 4.4 4.9 5.2 31.3 48.1 30.5 2.3 3.7 70.2 108.0 41.1 204.9 11.7 36.6 67.1 469.6 18.6 53.5 38.6 25.0 29.7 11.3 39.7 7.9 94.1 4.0 26.3 65.8 61.1 23.9 1.7 8.3 42.3 18.5 68.1 7.7 43.6 10.1 35.7 32.2 11.8 10.4 5.0 43.9 31.3 28.5 7.5 45.7 6.8 109.6 25.3 28.4 146.1 16.7 30.6 13.4 28.1 6.6 63.4 40.2 260.7 3.3 131.8 18.4 10.8 42.2 15.0 46.0 90.6 92.9 6.5 11.1 103.8 60.0 24.8 14.6 27.9 39.2 98.3 SWAP70 "KIAA0640, SWAP-70" ENSG00000133789 "Switching B cell complex subunit SWAP70" Q9UH65 11 9664077-9752993 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 80.6;naive B-cell: 84.8" "Group enriched" "Detected in all" 7 "B-cells: 84.8;granulocytes: 48.6;monocytes: 29.6" "Cell line enhanced" "Detected in many" "Daudi: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006810, HPA006929" Supported Supported "Plasma membrane,Actin filaments" NA NA 21000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Actin filaments" "HPA006810: AB_1857683, HPA006929: " "unprognostic (4.16e-2)" "unprognostic (7.06e-2)" "unprognostic (2.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.67e-1)" "unprognostic (3.38e-2)" "unprognostic (3.16e-3)" "unprognostic (1.26e-1)" "unprognostic (4.04e-1)" "unprognostic (3.33e-1)" "unprognostic (1.75e-1)" "unprognostic (3.85e-2)" "unprognostic (2.79e-3)" "unprognostic (5.00e-2)" "unprognostic (1.14e-1)" "unprognostic (3.61e-1)" "unprognostic (1.44e-1)" 39.3 10.4 12.8 37.5 13.7 20.9 31.9 13.6 15.9 22.6 17.2 15.0 15.4 17.8 10.4 17.8 16.3 22.0 16.2 12.2 14.1 17.2 10.0 24.9 66.1 16.7 13.6 10.2 15.0 19.4 5.7 39.0 16.7 14.1 12.8 3.9 18.0 15.3 9.8 26.4 20.3 19.7 16.5 59.5 15.9 4.8 14.3 17.3 22.3 14.7 75.3 31.2 17.6 16.5 40.6 22.2 30.8 0.1 62.9 54.6 54.0 43.4 52.6 40.3 44.1 24.7 31.3 161.0 41.6 83.5 57.9 47.7 37.9 24.2 51.6 14.8 15.2 42.6 25.7 12.1 35.2 33.3 76.2 38.4 29.6 29.5 52.3 32.6 124.4 20.2 3.9 0.6 42.4 6.4 10.0 16.1 28.4 10.7 11.3 23.6 28.9 4.7 33.6 106.1 1.5 15.5 41.3 52.6 35.2 42.9 20.9 25.1 143.6 70.3 25.1 59.4 41.2 4.2 12.4 111.5 27.9 36.6 29.3 19.7 5.7 48.6 1.2 13.5 0.5 80.6 1.4 1.1 8.2 84.8 1.2 1.3 1.1 7.9 29.6 2.3 4.2 5.4 12.8 13.7 13.6 15.9 12.2 14.1 16.7 13.6 16.7 16.5 14.3 16.5 154.0 67.3 60.8 33.0 183.7 35.6 68.1 40.1 36.5 3.4 35.1 28.3 17.6 22.8 57.7 20.2 0.0 82.6 9.9 11.3 13.7 47.4 1.6 66.5 18.6 136.0 13.1 9.7 9.0 21.6 128.0 39.1 15.8 71.6 137.8 10.3 53.2 7.2 65.0 26.9 14.5 8.7 18.3 61.9 50.8 2.9 29.8 58.5 28.4 77.8 88.8 9.2 6.2 22.1 22.4 37.0 15.1 34.6 20.7 63.0 22.4 11.7 50.9 2.3 19.7 46.2 35.5 5.5 10.8 17.4 31.3 140.1 15.5 33.4 9.0 78.8 SYMPK "SPK, SYM" ENSG00000125755 Symplekin Q92797 19 45815410-45863194 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 141.6;Late spermatids: 146.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041756, HPA042449" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA041756: AB_10963544, HPA042449: AB_2678003" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (1.21e-1)" "unprognostic (2.59e-1)" "unprognostic (1.59e-2)" "unprognostic (3.11e-2)" "unprognostic (2.33e-3)" "unprognostic (9.93e-2)" "unprognostic (9.78e-2)" "unprognostic (1.23e-1)" "unprognostic (9.16e-3)" "unprognostic (1.67e-2)" "unprognostic (1.44e-1)" "unprognostic (2.34e-1)" "unprognostic (1.29e-1)" "unprognostic (2.58e-1)" "unprognostic (6.38e-2)" 18.0 17.3 15.5 29.3 17.0 27.4 18.0 12.5 19.8 24.1 11.9 22.5 22.2 25.3 20.1 19.7 23.5 18.0 17.5 14.9 14.1 19.1 21.4 20.6 34.8 18.9 15.6 23.6 19.1 20.7 32.6 25.0 17.1 23.8 14.1 15.7 24.7 16.4 38.5 25.3 22.8 16.1 11.4 28.5 22.9 41.0 16.6 30.0 24.0 18.9 22.8 20.7 19.9 22.7 57.7 101.0 40.4 29.9 39.0 46.8 67.7 44.5 32.0 45.8 51.0 45.8 51.1 101.6 30.2 51.0 25.7 46.2 55.1 49.9 40.0 79.4 62.2 58.7 68.9 47.5 43.7 64.9 65.6 36.1 29.2 49.3 55.4 31.2 47.6 52.6 79.3 64.4 39.4 54.8 61.0 70.3 34.0 50.0 23.9 64.6 46.4 62.6 31.8 102.7 46.0 57.7 55.1 35.5 36.7 40.3 48.4 89.4 53.5 37.1 58.5 28.8 66.9 84.1 173.1 81.5 42.4 42.8 61.8 1.7 3.0 1.5 2.0 2.5 1.9 2.9 1.8 3.2 2.8 4.8 1.5 1.4 3.4 2.7 5.0 5.8 1.4 2.1 15.5 17.0 12.5 19.8 14.9 14.1 18.9 15.6 17.1 11.4 16.6 22.7 14.7 0.0 7.7 34.9 30.2 20.9 18.7 15.6 18.2 21.6 17.4 15.4 7.0 22.8 12.0 25.8 35.5 35.5 20.9 32.7 54.8 21.6 141.6 24.9 29.9 23.4 36.3 26.5 24.6 17.5 34.5 17.5 41.8 27.7 12.7 35.1 26.0 31.8 18.2 21.9 27.1 38.7 10.2 27.0 25.6 146.4 19.3 24.4 14.2 19.7 47.3 11.3 32.0 29.1 28.4 20.4 25.5 21.1 19.8 21.5 30.8 14.9 15.6 27.4 19.7 17.4 20.4 35.3 34.1 14.4 21.3 57.3 21.2 21.9 38.6 20.6 SYTL2 "CHR11SYT, exophilin-4, FLJ20163, FLJ21219, KIAA1597, MGC102768, PPP1R151, SGA72M, SLP2" ENSG00000137501 "Synaptotagmin like 2" Q9HCH5 11 85694224-85811159 "Plasma proteins, Predicted intracellular proteins, Transporters" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 74.2;stomach 1: 127.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 382.2;granulocytes: 130.8;Intestinal goblet cells: 185.9;Respiratory ciliated cells: 138.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 14.0;MAIT T-cell: 23.7" "Lineage enriched" "Detected in many" 5 "T-cells: 23.7" "Cell line enhanced" "Detected in many" "MCF7: 91.1;OE19: 148.1;RH-30: 175.8;RPTEC TERT1: 124.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039651 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Golgi apparatus" "Plasma membrane" "HPA039651: AB_10795153" "unprognostic (8.07e-3)" "unprognostic (6.72e-3)" "prognostic favorable (2.67e-4)" "unprognostic (9.34e-4)" "unprognostic (6.60e-3)" "unprognostic (2.19e-4)" "unprognostic (2.24e-2)" "unprognostic (5.37e-2)" "unprognostic (5.56e-2)" "unprognostic (5.45e-2)" "unprognostic (1.92e-2)" "unprognostic (2.97e-2)" "unprognostic (2.85e-2)" "unprognostic (4.03e-1)" "unprognostic (1.87e-2)" "unprognostic (9.72e-2)" "prognostic favorable (9.07e-4)" 16.7 9.6 19.3 12.9 24.6 3.3 16.0 8.7 35.7 10.7 11.9 51.7 21.6 9.1 16.3 17.0 7.6 27.8 8.4 29.0 25.1 20.2 6.9 14.8 11.1 26.4 14.0 4.8 2.7 6.4 6.1 18.2 17.9 13.6 74.2 13.3 8.9 9.8 5.1 6.8 25.0 10.2 15.6 10.4 127.7 5.1 13.8 7.1 4.7 2.7 6.8 50.9 7.4 29.1 3.5 8.0 12.2 1.0 2.8 15.4 0.2 30.3 39.4 26.3 59.2 34.7 4.5 0.7 11.1 21.3 38.0 22.3 0.8 2.7 34.5 2.4 0.2 0.0 0.2 0.3 1.8 2.7 0.5 19.6 3.8 56.8 0.8 6.2 0.2 1.0 0.4 0.4 33.6 91.1 0.1 0.9 20.6 148.1 13.6 1.3 175.8 0.1 124.2 46.8 0.3 0.6 6.7 5.4 3.0 10.2 0.6 0.5 0.1 40.8 15.6 25.9 1.5 0.2 0.0 16.1 41.9 0.5 25.7 0.0 0.0 0.0 14.0 0.0 23.7 0.0 2.8 8.4 0.0 0.1 2.3 4.1 0.0 4.6 0.1 1.0 1.1 2.6 19.3 24.6 8.7 35.7 29.0 25.1 26.4 14.0 17.9 15.6 13.8 29.1 7.5 22.4 32.5 15.3 3.0 3.6 11.7 15.8 1.8 10.4 45.4 14.0 2.3 8.6 62.1 68.0 8.4 0.7 45.6 115.2 0.0 9.1 1.2 8.0 2.2 6.4 19.2 4.0 103.9 16.9 0.4 11.5 382.2 2.3 130.8 0.8 5.0 0.5 0.5 1.7 23.2 185.9 2.0 5.9 5.0 0.9 1.8 4.6 10.6 20.6 1.6 14.0 63.8 35.7 91.9 16.5 40.6 30.1 31.6 30.7 16.3 8.6 138.4 8.1 32.9 42.1 59.8 3.6 2.6 2.2 5.7 0.4 50.1 2.3 36.7 60.9 SYVN1 "DER3, HRD1" ENSG00000162298 "Synoviolin 1" Q86TM6 11 65121780-65134532 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Stress response, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 72.9;Plasma cells: 90.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 205.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005480, HPA024300, CAB037030" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "Endoplasmic reticulum, Plasma membrane" "CAB037030: AB_1840939, HPA005480: AB_1079084, HPA024300: AB_1851073" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.22e-1)" "unprognostic (2.17e-2)" "unprognostic (2.85e-2)" "prognostic favorable (6.88e-4)" "unprognostic (7.67e-2)" "unprognostic (2.50e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.77e-2)" "unprognostic (1.56e-2)" "unprognostic (4.89e-1)" "unprognostic (3.85e-2)" "unprognostic (1.16e-1)" 29.2 40.3 19.3 37.1 25.6 31.0 27.6 23.2 21.4 30.7 26.7 29.2 26.1 29.1 38.8 28.4 30.6 19.7 25.3 18.6 21.2 24.5 117.5 27.0 60.9 27.9 25.6 30.9 90.9 35.0 38.2 26.2 24.6 28.5 29.0 18.7 55.9 30.3 34.2 29.3 39.4 25.9 22.8 51.2 39.4 24.3 23.4 18.3 43.4 19.0 81.1 25.8 24.8 25.9 32.4 40.6 24.0 32.5 59.8 33.8 23.8 32.8 33.5 40.9 28.8 22.2 55.0 181.0 43.8 42.4 53.8 48.8 26.4 33.3 33.6 28.4 20.0 28.6 46.8 50.2 72.3 43.3 49.6 43.3 59.0 36.1 81.0 36.4 27.0 19.0 36.4 90.1 24.3 47.9 19.1 31.2 26.1 33.6 28.0 31.9 20.3 74.0 25.7 31.5 15.6 32.0 30.4 74.1 53.3 21.0 55.4 28.2 25.9 28.3 18.6 51.2 22.4 178.1 134.2 205.9 38.1 21.8 32.3 16.8 7.4 14.0 7.4 4.7 6.5 21.9 5.2 6.9 4.4 22.6 3.7 3.9 7.0 3.5 4.7 18.4 5.3 6.6 19.3 25.6 23.2 21.4 18.6 21.2 27.9 25.6 24.6 22.8 23.4 25.9 11.5 16.0 21.4 11.1 43.5 17.6 6.9 13.8 12.0 10.7 21.0 15.5 4.0 22.8 20.8 11.0 33.3 14.5 16.4 23.1 1.9 13.6 6.6 14.2 16.2 11.3 8.4 13.2 9.6 18.9 16.5 14.2 17.9 22.1 1.3 10.1 15.0 72.9 15.1 13.5 9.5 33.6 16.2 15.3 13.2 4.1 20.5 10.8 12.4 9.4 10.5 11.0 13.4 13.0 15.8 18.2 11.7 13.2 90.5 14.9 14.0 7.7 15.1 18.7 13.1 11.9 10.7 19.3 13.2 9.7 16.1 42.8 11.7 13.6 18.6 13.8 TACSTD2 "EGP-1, GA733-1, M1S1, TROP2" ENSG00000184292 "Tumor associated calcium signal transducer 2" P09758 1 58575433-58577252 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Tumor antigen" "Amyloidosis, Corneal dystrophy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 989.6;salivary gland: 468.5;skin 1: 438.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 6559.0;Basal respiratory cells: 3141.0;Club cells: 2499.0;Prostatic glandular cells: 3724.1;Squamous epithelial cells: 2716.6;Urothelial cells: 8102.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 15.0" "Group enriched" "Detected in many" 79 "dendritic cells: 4.3;granulocytes: 15.0;monocytes: 4.2" "Cell line enhanced" "Detected in many" "A-431: 766.6;CAPAN-2: 1005.9;HaCaT: 1010.0;RT4: 355.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043104, HPA055067, CAB072852" Enhanced Supported "Nucleoli,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "Nucleoli, Vesicles" "CAB072852: , HPA043104: AB_10960710, HPA055067: AB_2682687" "unprognostic (1.80e-2)" "unprognostic (3.08e-1)" "unprognostic (3.67e-3)" "unprognostic (1.22e-1)" "unprognostic (5.70e-2)" "unprognostic (2.15e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "unprognostic (7.91e-2)" "prognostic favorable (3.99e-4)" "unprognostic (7.10e-2)" "unprognostic (2.55e-1)" "unprognostic (6.91e-3)" "unprognostic (2.50e-1)" 4.8 1.2 0.2 1.3 0.4 13.5 135.8 0.2 0.4 218.6 1.9 1.1 0.7 19.1 25.3 989.6 27.7 13.0 0.8 0.3 0.3 137.9 4.0 71.2 1.0 0.2 0.3 1.5 81.1 3.5 2.4 17.7 0.2 126.8 0.9 0.0 468.5 97.1 1.9 438.8 1.2 2.0 0.2 1.0 65.7 0.5 0.3 9.2 5.0 0.3 180.0 234.6 375.0 0.6 766.6 0.1 0.0 1.5 0.0 0.0 280.1 0.2 0.0 0.0 0.1 0.7 1005.9 0.1 94.7 64.2 0.1 1010.0 0.0 186.5 0.0 0.7 0.0 0.2 19.7 0.3 0.3 0.1 0.8 0.2 274.5 0.4 11.3 0.0 42.5 0.0 0.2 1.3 0.0 166.3 0.6 1.1 0.5 167.0 1.4 0.2 0.1 0.6 137.0 355.3 0.2 0.3 32.4 264.9 1.0 3.2 173.6 1.5 45.4 1.0 1.7 0.8 1.7 0.4 0.9 0.7 1.0 0.3 0.7 0.0 4.2 15.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.8 0.2 0.4 0.2 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.3 0.6 9.0 346.1 109.2 0.0 3.1 1490.5 6559.0 3141.0 1226.5 0.0 789.8 445.6 0.4 338.8 2499.0 1278.2 0.0 107.1 9.1 2.8 43.0 2165.2 0.0 482.3 48.6 60.4 0.0 0.0 0.1 1263.4 8.1 36.3 143.2 608.7 8.8 0.2 1.4 0.5 8.8 0.0 0.0 8.5 1143.4 0.8 203.4 0.0 0.0 34.8 113.8 0.0 31.3 0.0 0.0 0.0 0.6 1778.0 3.6 0.0 1.4 3724.1 0.2 3.4 1080.4 0.0 0.0 1.3 142.4 0.4 1.1 2716.6 1531.8 78.4 32.8 0.0 1.5 8102.8 TBC1D24 "DFNA65, DFNB86, KIAA1171, TLDC6" ENSG00000162065 "TBC1 domain family member 24" Q9ULP9 16 2475051-2509560 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Deafness, Disease variant, Epilepsy, Mental retardation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 16.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 43.8;Inhibitory neurons: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SCLC-21H: 34.7" "HPA044712, HPA068080" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cell Junctions" "HPA044712: AB_10795619, HPA068080: AB_2685948" "prognostic unfavorable (3.22e-4)" "unprognostic (5.23e-2)" "unprognostic (4.02e-2)" "unprognostic (6.41e-2)" "unprognostic (3.52e-1)" "unprognostic (1.52e-2)" "unprognostic (1.40e-1)" "unprognostic (2.03e-2)" "unprognostic (1.68e-1)" "unprognostic (7.37e-2)" "unprognostic (4.37e-2)" "unprognostic (1.28e-1)" "unprognostic (4.66e-3)" "unprognostic (2.02e-2)" "unprognostic (8.19e-2)" "unprognostic (7.78e-3)" "unprognostic (1.61e-1)" 3.8 3.3 7.5 1.8 8.1 2.5 2.8 3.6 10.5 2.1 0.0 2.0 2.2 1.4 2.8 1.0 2.3 1.9 3.0 8.3 3.7 4.3 3.7 3.9 1.8 2.9 2.9 1.0 10.6 1.9 2.6 2.1 3.1 2.5 0.9 4.2 16.5 3.5 3.4 1.2 1.6 1.7 1.9 2.0 2.2 1.2 4.4 0.9 3.1 1.7 1.2 1.8 0.9 2.8 3.4 6.7 4.5 9.2 5.1 5.1 3.8 6.2 3.3 4.0 3.5 6.2 2.9 8.6 5.2 4.9 1.9 6.3 7.1 2.0 2.9 9.3 8.0 8.0 9.5 5.5 3.1 5.9 3.2 1.9 2.8 3.5 1.4 2.8 5.1 3.3 9.9 4.8 3.8 6.4 4.1 11.9 4.0 3.2 4.3 20.9 8.5 6.1 2.9 2.3 34.7 8.5 3.8 15.3 2.6 1.6 4.8 5.2 5.4 7.8 8.4 7.9 6.2 3.2 3.0 11.0 3.4 8.5 7.2 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 7.5 8.1 3.6 10.5 8.3 3.7 2.9 2.9 3.1 1.9 4.4 2.8 4.7 28.9 26.7 15.7 1.9 0.5 3.0 1.4 1.8 19.0 17.8 10.8 6.9 10.0 6.9 5.5 43.8 1.5 5.6 2.4 33.2 5.0 0.2 2.8 10.0 5.4 11.4 6.5 29.6 6.1 1.0 5.8 5.6 4.0 3.8 6.0 10.4 17.3 3.5 26.9 34.0 2.6 6.1 5.1 3.3 1.0 9.0 3.0 1.8 6.5 3.6 13.8 6.2 25.1 9.7 5.0 2.8 6.0 1.7 3.1 1.8 3.9 3.6 25.5 0.0 11.2 3.7 8.8 5.9 1.4 1.4 0.3 2.9 3.4 4.7 1.6 TBC1D30 KIAA0984 ENSG00000111490 "TBC1 domain family member 30" Q9Y2I9 12 64759484-64881033 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.1;pancreas: 12.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 30.9;Inhibitory neurons: 42.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 25.9;OE19: 11.9;RPMI-8226: 12.6;RT4: 12.8;SCLC-21H: 26.5;SK-BR-3: 16.7;T-47d: 14.5" "HPA039772, HPA040043" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Cytosol "HPA039772: AB_10795409, HPA040043: AB_10795411" "unprognostic (1.85e-1)" "unprognostic (6.95e-2)" "unprognostic (2.66e-1)" "prognostic favorable (3.61e-5)" "unprognostic (9.35e-2)" "unprognostic (2.09e-1)" "unprognostic (2.65e-5)" "prognostic favorable (5.08e-4)" "unprognostic (1.75e-3)" "unprognostic (2.16e-2)" "unprognostic (2.44e-1)" "unprognostic (9.72e-2)" "unprognostic (7.32e-2)" "unprognostic (7.62e-3)" "unprognostic (8.72e-2)" "unprognostic (2.67e-3)" "unprognostic (7.80e-3)" 1.5 1.1 2.0 1.0 2.7 0.3 2.3 4.9 10.1 3.0 1.4 1.4 1.8 1.4 1.8 0.6 1.5 1.8 0.6 5.3 1.7 2.2 1.2 2.3 0.4 6.8 1.8 0.9 12.0 2.4 6.4 0.6 6.9 3.0 1.5 2.2 6.8 2.7 0.3 0.8 1.6 0.9 2.0 1.9 3.9 1.9 2.0 0.3 1.5 0.3 0.3 3.3 1.3 3.8 5.1 1.0 0.5 0.3 0.1 0.6 0.7 0.0 0.0 0.1 0.0 4.3 1.8 0.1 0.9 0.1 0.3 0.1 5.3 0.2 0.0 0.0 3.8 0.3 1.4 0.1 0.0 4.0 0.8 0.3 0.1 0.0 0.0 0.6 3.8 1.2 0.0 2.0 0.3 25.9 0.0 0.6 1.1 11.9 5.2 0.2 0.1 12.6 0.9 12.8 26.5 1.8 1.4 16.7 0.3 0.3 14.5 1.4 4.2 0.0 0.9 0.9 2.5 0.0 0.0 0.1 0.1 0.4 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.0 2.7 4.9 10.1 5.3 1.7 6.8 1.8 6.9 2.0 2.0 3.8 5.1 0.0 6.3 4.9 0.6 0.9 4.6 0.9 0.0 9.3 7.2 3.8 0.6 5.7 4.5 3.7 8.4 0.7 1.5 2.5 9.8 3.9 14.2 2.2 0.8 6.5 0.0 0.0 30.9 4.9 0.3 0.7 3.6 4.2 8.9 0.8 1.8 0.3 1.6 0.0 42.8 6.4 6.1 4.0 6.2 1.9 0.3 3.0 5.4 12.2 1.2 2.6 0.0 1.5 2.0 2.7 4.9 0.0 0.6 9.1 3.9 2.3 1.8 0.6 0.0 0.6 1.0 3.7 3.0 0.3 1.4 0.1 0.8 0.4 4.4 8.7 TBXA2R ENSG00000006638 "Thromboxane A2 receptor" P21731 19 3594507-3606875 "Disease related genes, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Adipocytes: 10.8;Endothelial cells: 8.7;Hepatic stellate cells: 30.7;Macrophages: 19.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 9.5;U-2197: 6.8;U-937: 6.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA077366 Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "Nuclear speckles" "HPA077366: AB_2686836" "unprognostic (1.59e-1)" "unprognostic (3.86e-2)" "unprognostic (1.21e-2)" "unprognostic (1.74e-1)" "unprognostic (8.97e-2)" "unprognostic (4.19e-2)" "unprognostic (1.52e-2)" "unprognostic (2.17e-3)" "unprognostic (8.41e-2)" "unprognostic (6.25e-2)" "prognostic favorable (7.17e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (4.32e-2)" "unprognostic (9.63e-2)" "unprognostic (1.76e-1)" "unprognostic (2.02e-1)" 3.8 8.7 1.3 1.6 1.1 1.0 1.9 1.8 1.3 5.4 1.3 2.3 0.8 5.2 0.4 1.7 3.3 1.0 5.0 1.1 1.1 6.3 6.1 4.4 1.0 1.7 1.3 2.0 0.9 1.2 1.0 3.2 1.5 2.5 0.4 0.5 0.6 1.4 1.4 1.1 3.2 1.8 1.1 7.0 2.5 0.6 1.4 0.3 2.6 0.6 0.3 2.6 3.6 2.1 0.2 0.2 0.3 3.4 0.7 1.7 0.5 2.4 0.6 1.8 1.4 0.1 0.3 0.1 3.5 1.0 1.8 0.2 0.7 0.0 0.7 0.2 0.8 2.3 9.5 0.2 0.9 0.2 4.1 0.8 0.0 2.4 0.0 1.4 0.7 0.1 3.8 0.4 0.3 0.1 0.2 1.2 0.3 0.1 2.1 0.1 0.0 0.1 0.0 0.1 0.1 1.3 0.2 0.4 0.1 0.3 1.5 4.2 2.1 3.8 0.8 6.8 2.3 0.2 0.3 0.2 3.1 6.1 0.9 3.7 0.4 0.4 2.5 0.2 0.3 2.0 0.7 2.2 0.1 11.1 4.3 9.4 4.1 3.3 0.3 0.3 0.2 4.0 1.3 1.1 1.8 1.3 1.1 1.1 1.7 1.3 1.5 1.1 1.4 2.1 10.8 0.0 0.0 0.0 2.6 0.5 0.1 0.0 0.0 0.3 0.1 0.1 1.3 0.0 0.0 1.8 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.1 0.6 8.7 0.0 0.0 0.3 0.0 0.2 2.3 0.0 0.1 0.0 0.2 30.7 0.6 0.9 0.0 0.9 0.0 0.0 1.0 0.3 0.0 0.3 19.2 1.8 1.9 0.3 0.5 1.0 0.5 0.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 2.5 0.4 1.9 0.1 0.6 0.1 0.8 0.4 0.1 0.0 TCAF2 "FAM115C, FAM139A, FLJ40722, GATD9" ENSG00000170379 "TRPM8 channel associated factor 2" A6NFQ2 7 143620952-143730409 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.2;Hepatocytes: 12.3;Syncytiotrophoblasts: 15.7;T-cells: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 10.6;HUVEC TERT2: 11.6;TIME: 18.5;U-87 MG: 13.8" "HPA038756, HPA038758" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane, Cell Junctions" "HPA038756: AB_10960427, HPA038758: AB_10960353" "unprognostic (6.59e-2)" "unprognostic (4.99e-2)" "unprognostic (2.34e-2)" "unprognostic (8.86e-3)" "prognostic unfavorable (9.53e-5)" "unprognostic (1.89e-1)" "unprognostic (3.11e-2)" "unprognostic (4.47e-2)" "unprognostic (2.36e-1)" "unprognostic (2.04e-2)" "unprognostic (3.98e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.17e-6)" "unprognostic (7.19e-2)" "unprognostic (4.02e-2)" "unprognostic (5.41e-3)" "unprognostic (2.85e-2)" 2.1 1.9 1.5 4.0 1.5 4.1 5.8 4.6 3.4 4.0 0.0 1.2 1.0 1.7 0.8 9.2 1.9 2.2 1.2 1.5 1.9 2.6 4.5 3.7 4.2 2.2 2.5 2.6 2.0 2.1 2.6 5.2 2.5 2.8 1.1 3.2 3.7 1.2 0.7 4.3 2.4 1.5 0.7 2.8 2.0 1.6 1.7 3.3 1.3 0.7 3.4 2.8 5.9 3.2 5.5 0.3 0.1 0.2 1.0 1.0 2.0 1.5 3.1 0.7 2.2 0.1 0.3 0.2 2.1 1.3 0.5 0.8 0.1 3.0 2.3 10.6 0.5 0.8 0.6 0.1 1.2 0.3 0.4 2.9 1.3 0.3 0.9 2.1 11.6 0.7 3.0 5.1 4.3 0.8 0.6 0.8 0.2 5.0 2.7 0.4 2.1 2.4 0.0 1.9 0.1 0.1 0.5 4.3 0.2 0.8 1.9 0.2 18.5 1.3 0.9 5.5 0.4 7.7 2.6 0.1 13.8 0.4 3.2 5.7 0.2 0.2 2.9 0.2 3.1 1.9 4.8 3.1 0.2 1.8 4.2 3.3 0.9 2.2 0.2 0.7 5.6 1.2 1.5 1.5 4.6 3.4 1.5 1.9 2.2 2.5 2.5 0.7 1.7 3.2 0.5 0.0 1.8 0.0 4.5 0.0 1.3 0.0 3.4 0.7 5.6 3.4 0.4 0.0 1.8 0.0 0.0 16.2 5.6 0.2 0.0 0.9 1.0 0.8 1.4 3.5 0.0 0.4 3.7 0.4 4.9 2.4 2.6 1.3 2.5 0.3 0.7 12.3 2.0 0.0 3.6 0.2 0.0 1.6 0.0 1.1 1.8 1.8 0.0 0.0 0.4 2.1 7.2 1.5 0.1 1.3 0.1 0.7 5.0 2.1 2.1 0.4 0.0 0.1 0.0 2.3 1.1 3.5 2.0 4.9 0.0 15.7 9.1 0.8 0.4 1.1 TCAF2C ENSG00000283528 "TRPM8 channel associated factor 2C" 7 143639230-143647646 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA038756, HPA038758" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 35: T-regs - Unknown function" "Plasma membrane, Cell Junctions" "HPA038756: AB_10960427, HPA038758: AB_10960353" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.7 0.0 0.5 0.3 0.8 0.4 0.0 0.3 0.5 0.5 0.0 0.7 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TEC PSCTK4 ENSG00000135605 "Tec protein tyrosine kinase" P42680 4 48135783-48269838 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 13.9;Glandular and luminal cells: 25.1;granulocytes: 19.6;Plasma cells: 15.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basophil: 20.7;eosinophil: 13.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 20.7" "Cell line enhanced" "Detected in many" "HEL: 13.5;HMC-1: 20.3;U-266/70: 20.3;U-266/84: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005733, HPA024657" Approved Supported "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA005733: AB_1857878, HPA024657: AB_2671637" "unprognostic (7.19e-2)" "unprognostic (1.44e-1)" "unprognostic (1.41e-2)" "unprognostic (4.07e-3)" "unprognostic (4.21e-2)" "unprognostic (8.57e-2)" "unprognostic (3.14e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-2)" "prognostic favorable (7.12e-4)" "unprognostic (7.46e-3)" "unprognostic (7.83e-2)" "unprognostic (1.01e-4)" "unprognostic (4.24e-2)" "unprognostic (2.16e-1)" "unprognostic (7.39e-2)" "unprognostic (4.96e-3)" 0.9 1.7 0.1 2.1 0.2 6.1 1.4 0.1 0.4 1.2 1.0 1.3 1.6 1.1 4.2 3.4 1.9 1.1 1.3 0.0 0.4 1.1 2.5 2.0 3.1 1.1 0.3 0.4 0.8 1.2 0.6 1.1 1.1 0.5 1.3 1.8 2.3 1.0 0.6 3.6 1.5 0.8 0.3 1.7 1.1 1.2 0.7 2.0 1.3 0.5 3.3 1.0 1.6 0.2 3.0 0.8 0.0 0.0 0.0 0.0 0.1 0.5 2.2 1.3 2.7 0.0 2.2 1.9 2.0 0.0 0.1 0.6 1.1 0.0 1.8 0.1 0.8 13.5 1.0 0.1 0.0 2.2 20.3 0.0 0.3 1.7 0.0 1.4 0.0 0.6 7.5 0.5 4.1 1.0 1.3 4.9 0.4 1.4 0.8 3.1 2.7 0.0 3.4 0.9 0.0 0.2 0.6 0.3 0.5 1.1 0.7 4.2 0.0 0.0 0.0 2.8 0.0 20.3 15.4 2.6 0.0 3.0 0.1 20.7 0.6 13.3 0.1 0.7 0.3 1.0 0.2 0.5 1.5 0.7 0.5 0.5 0.5 3.6 0.1 0.1 0.1 0.4 0.1 0.2 0.1 0.4 0.0 0.4 1.1 0.3 1.1 0.3 0.7 0.2 0.6 6.4 6.8 0.7 6.8 2.5 1.7 0.2 2.8 0.9 1.7 1.1 1.8 7.2 2.6 0.0 0.0 1.5 3.3 2.1 0.0 1.7 6.4 13.9 1.5 1.2 3.0 12.6 6.7 1.1 0.1 0.8 0.0 25.1 19.6 0.7 0.0 2.9 4.9 0.0 1.6 1.4 4.1 4.6 1.8 2.6 0.0 5.9 1.8 10.3 1.7 6.6 0.0 0.5 0.2 1.0 0.6 0.4 15.4 1.3 3.0 2.0 0.2 3.1 6.6 1.8 0.8 0.7 1.4 9.8 3.0 0.8 3.4 0.3 2.1 1.6 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.3" "Group enriched" "Detected in many" 10 "Adipocytes: 70.8;Endothelial cells: 73.9;Hepatic stellate cells: 122.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 90.9;NTERA-2: 45.2;TIME: 99.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 20.1 9.1 8.1 5.8 7.0 0.2 14.0 6.1 8.4 9.3 4.3 5.0 3.7 12.4 2.3 5.3 6.7 11.2 16.8 7.1 6.8 23.0 10.5 28.8 3.7 7.2 6.6 3.5 3.5 4.4 3.0 46.3 7.6 3.8 5.4 0.7 3.1 6.2 10.5 2.8 5.5 12.7 6.8 28.8 4.0 1.4 9.4 1.8 9.1 22.9 2.8 6.9 3.9 6.8 0.3 0.0 3.5 0.0 0.4 5.6 0.1 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 2.4 0.0 1.6 0.0 0.0 1.8 0.0 2.2 0.8 0.1 90.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 45.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 18.3 0.0 0.0 99.1 0.0 0.5 9.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.1 8.4 7.1 6.8 7.2 6.6 7.6 6.8 9.4 6.8 70.8 3.2 1.3 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.5 8.6 0.0 0.6 1.8 0.0 0.4 0.4 0.0 0.0 0.0 0.6 0.6 0.8 73.9 0.0 2.7 4.3 0.0 2.8 4.2 0.0 0.7 0.0 0.3 122.0 1.3 0.3 0.0 5.0 0.0 0.0 6.7 2.2 0.9 0.6 0.4 0.0 38.4 0.0 0.1 0.0 137.7 2.1 1.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.2 0.0 1.6 1.9 0.1 0.4 0.3 1.3 1.4 0.5 1.8 0.0 0.0 TGFBR1 "ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI" ENSG00000106799 "Transforming growth factor beta receptor 1" P36897 9 99104038-99154192 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 128.4;Late spermatids: 101.7;Microglial cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 253.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002441, CAB031481, HPA056473" Uncertain Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "CAB002441: AB_564029, CAB031481: AB_2202455, HPA056473: AB_2683144" "unprognostic (2.58e-3)" "unprognostic (1.20e-2)" "unprognostic (3.64e-3)" "unprognostic (2.80e-1)" "unprognostic (8.63e-2)" "unprognostic (3.36e-2)" "unprognostic (1.97e-2)" "unprognostic (1.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (8.21e-3)" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.01e-3)" "unprognostic (3.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.14e-2)" 15.9 9.9 9.8 18.2 9.3 33.7 15.4 13.2 8.9 19.4 11.8 18.8 11.7 20.6 8.8 15.0 8.5 21.7 8.2 6.8 11.3 22.6 14.8 16.3 13.8 18.4 14.5 13.0 8.3 8.5 7.6 48.8 20.0 17.1 13.4 4.7 8.3 16.8 8.7 6.2 9.3 33.0 18.0 16.5 18.4 18.3 17.5 11.2 11.2 13.2 13.6 22.5 8.4 27.9 13.7 19.5 115.5 36.1 26.2 19.3 17.4 44.1 47.8 40.7 44.9 19.9 9.3 29.7 13.4 34.6 32.1 30.4 39.6 34.1 54.0 77.1 12.3 43.9 20.7 17.8 43.2 27.2 102.8 40.2 35.4 62.8 29.5 25.2 7.4 10.9 62.4 12.1 55.4 20.3 4.0 31.0 24.7 12.2 11.5 11.0 253.1 12.5 9.9 3.8 31.1 36.2 34.3 150.2 46.4 47.3 28.1 36.6 13.6 29.8 25.5 129.3 27.3 12.1 13.4 20.0 62.5 45.9 26.2 16.2 2.4 9.5 7.8 1.6 6.7 1.6 3.3 5.8 2.0 1.2 3.2 6.2 4.9 4.3 2.0 1.4 2.4 2.2 9.8 9.3 13.2 8.9 6.8 11.3 18.4 14.5 20.0 18.0 17.5 27.9 13.5 6.4 8.8 18.9 18.9 23.6 7.4 19.9 44.3 8.0 18.9 11.7 7.6 4.3 12.8 60.7 0.0 23.0 37.3 5.0 0.0 18.8 128.4 6.4 22.7 17.6 9.6 7.4 14.2 31.2 6.7 36.0 9.2 9.3 29.9 19.5 6.4 12.7 49.4 0.0 8.6 7.3 8.2 32.4 52.5 101.7 9.6 39.7 35.6 116.2 24.3 3.1 35.0 45.8 21.1 33.8 4.2 13.5 11.9 18.4 3.6 13.8 5.0 2.0 32.9 21.8 20.9 11.0 12.7 25.6 16.2 19.4 25.4 7.6 8.3 11.5 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 391.5;Endothelial cells: 236.4;Hepatic stellate cells: 478.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.6;ASC TERT1: 472.3;HSkMC: 430.0;LHCN-M2: 381.7;TIME: 418.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 230.0 56.1 16.5 73.8 12.9 29.4 145.7 13.8 19.3 90.0 30.6 96.0 44.2 69.1 18.2 44.9 69.6 91.9 95.2 10.6 13.4 67.9 59.1 148.0 70.1 17.6 16.5 26.6 52.0 59.0 16.9 81.6 16.7 44.1 54.1 2.1 49.2 60.8 31.1 39.1 77.7 107.2 17.3 111.1 63.4 7.8 21.5 49.7 91.8 62.2 60.7 98.0 55.1 17.2 16.6 100.2 5.3 0.1 313.6 472.3 15.9 83.9 116.1 28.5 27.7 22.9 86.6 2.2 298.2 117.2 32.2 33.3 4.0 125.4 42.0 7.0 8.9 10.1 10.7 104.5 128.5 14.9 76.6 430.0 93.6 126.3 114.4 117.0 296.0 10.9 1.8 0.0 381.7 1.3 16.2 10.5 2.2 75.7 39.8 14.1 36.4 2.1 113.5 40.5 0.1 5.6 24.9 6.1 22.0 6.6 0.0 14.0 418.6 134.7 33.2 61.4 32.0 2.8 0.3 12.5 80.1 16.1 55.8 9.0 3.0 11.5 3.4 3.1 3.3 4.5 4.8 3.3 2.6 6.4 16.6 7.3 13.1 1.9 8.0 6.6 0.7 3.8 16.5 12.9 13.8 19.3 10.6 13.4 17.6 16.5 16.7 17.3 21.5 17.2 391.5 144.2 99.7 0.7 77.0 37.3 18.9 23.5 39.9 5.1 23.7 24.1 84.5 50.1 39.5 27.6 0.0 6.8 85.3 10.5 3.9 13.1 2.5 28.3 57.5 236.4 8.4 20.4 0.4 15.8 5.1 129.2 39.3 30.8 29.8 0.7 478.0 55.5 30.4 0.0 1.0 12.4 22.4 147.0 58.0 3.8 32.9 67.9 30.2 170.5 47.5 0.2 56.7 6.0 2.4 37.6 12.1 47.4 37.5 8.6 13.6 7.2 14.7 1.2 32.9 60.8 53.4 0.3 1.2 8.0 30.5 3.7 68.2 1.7 14.5 10.8 TIGD7 Sancho ENSG00000140993 "Tigger transposable element derived 7" Q6NT04 16 3298808-3305729 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041357, HPA041474" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 24: NB-4 - Immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA041357: AB_10794992, HPA041474: AB_10795696" "unprognostic (7.69e-2)" "unprognostic (3.04e-4)" "unprognostic (6.56e-3)" "unprognostic (1.18e-3)" "unprognostic (1.79e-1)" "unprognostic (4.04e-2)" "unprognostic (6.50e-3)" "unprognostic (2.44e-1)" "unprognostic (2.78e-2)" "unprognostic (9.81e-2)" "unprognostic (8.56e-3)" "unprognostic (2.09e-1)" "unprognostic (2.25e-2)" "unprognostic (8.87e-2)" "unprognostic (4.04e-1)" "unprognostic (5.90e-3)" "unprognostic (3.12e-2)" 2.9 3.3 5.1 1.8 5.1 0.6 4.7 6.0 6.1 5.1 7.0 4.9 1.8 5.5 4.5 1.9 5.1 2.6 5.3 4.9 5.6 6.0 3.1 2.8 3.4 5.2 5.6 10.6 2.8 6.5 8.2 3.2 5.5 5.6 1.9 5.1 2.7 5.0 4.2 2.1 2.8 3.5 5.0 4.8 2.7 8.5 5.2 3.7 6.7 5.3 3.0 4.1 3.4 5.7 0.9 1.9 5.5 3.0 2.4 3.6 4.2 2.7 1.6 4.0 3.7 0.2 1.7 2.0 4.5 2.0 3.3 0.5 1.8 0.7 5.0 0.2 2.7 5.9 1.7 0.1 2.8 1.0 7.5 3.9 1.3 3.7 1.1 4.7 3.1 1.4 2.9 3.5 3.4 1.2 1.9 9.0 6.3 0.6 5.1 10.2 1.3 8.3 2.2 0.5 7.1 2.6 6.8 0.9 2.7 4.8 3.2 3.3 1.2 2.6 6.2 2.7 1.6 7.5 8.3 6.5 1.5 3.4 2.9 0.5 0.6 3.4 1.5 0.5 2.7 0.6 1.2 2.3 0.5 2.5 2.4 1.7 2.1 2.0 1.7 0.5 1.4 0.7 5.1 5.1 6.0 6.1 4.9 5.6 5.2 5.6 5.5 5.0 5.2 5.7 1.7 9.6 4.5 11.4 4.9 0.8 3.2 2.1 4.0 6.1 2.4 2.4 9.9 4.3 4.4 0.0 4.2 1.5 1.6 0.6 3.9 2.8 4.7 2.3 3.8 2.3 1.2 2.5 14.6 1.4 1.1 2.6 4.6 1.7 1.3 5.9 0.4 0.6 0.9 5.0 12.7 1.0 4.1 0.6 0.8 2.0 2.8 1.1 5.4 2.8 0.9 3.4 4.1 20.6 12.1 1.1 0.1 4.5 2.0 2.3 1.0 0.9 2.9 2.2 6.6 3.1 3.6 11.6 10.5 2.1 0.6 1.4 2.9 3.8 0.6 1.5 TLN1 "ILWEQ, TLN" ENSG00000137076 "Talin 1" Q9Y490 9 35696948-35732195 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 323.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002006, HPA004748" Supported Supported "Plasma membrane,Focal adhesion sites,Centriolar satellite,Cytosol" NA NA 1300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Focal adhesion sites, Cytosol" "Plasma membrane, Centriolar satellite" "CAB002006: , HPA004748: AB_1857760" "unprognostic (9.71e-2)" "unprognostic (2.02e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (1.96e-1)" "unprognostic (5.55e-2)" "unprognostic (2.52e-1)" "unprognostic (3.18e-2)" "unprognostic (5.07e-2)" "unprognostic (1.94e-1)" "unprognostic (6.46e-2)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "prognostic favorable (7.21e-4)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (7.83e-2)" "unprognostic (8.83e-3)" 125.7 62.7 31.1 84.7 42.1 79.2 79.4 39.3 31.1 80.0 43.1 196.2 36.5 151.8 25.3 78.0 102.9 53.2 81.2 26.2 34.9 47.3 42.3 91.8 63.1 50.8 41.9 66.0 33.1 41.6 36.7 70.4 49.7 72.6 41.4 7.7 42.5 111.4 70.9 46.7 77.9 145.4 41.5 89.7 91.8 23.3 44.9 61.1 49.0 55.8 52.7 147.7 66.3 44.6 63.4 103.8 62.7 86.9 210.8 158.7 71.4 171.2 186.8 162.9 146.4 86.3 27.4 76.5 55.5 319.0 103.0 33.3 74.2 106.9 118.3 172.8 48.0 173.0 132.1 77.4 130.6 105.8 276.2 193.4 50.2 240.1 112.7 223.7 253.4 64.7 60.2 76.0 218.5 27.8 71.5 27.8 51.3 28.4 78.8 95.0 36.6 44.8 81.4 49.8 14.1 59.6 83.7 46.3 53.4 56.5 39.3 72.6 308.5 257.8 99.6 80.0 140.6 26.2 27.6 51.7 199.9 55.9 238.4 6.0 5.9 7.3 5.4 6.1 4.4 2.6 3.1 4.1 4.3 2.3 1.4 3.1 10.0 4.1 8.1 5.4 2.3 6.9 31.1 42.1 39.3 31.1 26.2 34.9 50.8 41.9 49.7 41.5 44.9 44.6 123.2 109.0 66.9 11.4 99.8 40.1 69.4 43.5 42.7 11.7 40.3 61.3 134.1 31.5 55.7 53.3 10.4 44.3 186.3 43.8 23.5 94.3 47.2 36.0 156.9 106.8 34.1 127.0 7.7 61.9 82.6 103.9 51.0 73.0 206.6 72.0 93.9 54.7 112.4 15.2 7.6 29.0 26.4 196.9 91.0 26.4 99.4 323.4 23.2 21.5 174.1 33.0 288.4 4.5 9.1 107.7 33.2 128.6 61.4 58.4 40.6 62.8 34.3 17.6 203.8 126.5 267.9 32.0 28.5 47.4 26.6 58.8 143.8 89.4 28.9 46.4 TLR4 "ARMD10, CD284, hToll, TLR-4" ENSG00000136869 "Toll like receptor 4" O00206 9 117704175-117724735 "CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Age-related macular degeneration, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 38.6;Astrocytes: 50.9;Hepatic stellate cells: 62.8;Hofbauer cells: 38.2;Kupffer cells: 106.0;Macrophages: 64.5;monocytes: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 86.8" "Group enriched" "Detected in many" 33 "dendritic cells: 22.4;granulocytes: 86.8;monocytes: 65.6" "Cell line enhanced" "Detected in many" "Karpas-707: 60.0;TIME: 43.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004025, HPA049174" Approved Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Golgi apparatus" "CAB004025: , HPA049174: AB_2680662" "unprognostic (1.60e-1)" "unprognostic (8.34e-2)" "unprognostic (7.22e-2)" "prognostic favorable (6.29e-4)" "unprognostic (3.39e-1)" "unprognostic (7.48e-2)" "unprognostic (8.68e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (5.18e-2)" "unprognostic (8.00e-2)" "unprognostic (9.42e-2)" "unprognostic (4.08e-2)" "unprognostic (8.63e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (1.09e-2)" "unprognostic (1.96e-2)" 31.1 11.0 12.4 25.7 15.7 22.3 12.0 11.7 8.3 6.5 1.7 6.7 4.3 5.6 1.2 4.8 4.8 10.8 8.4 10.3 17.8 6.8 16.7 16.2 13.1 12.3 14.0 6.0 2.6 2.5 2.1 23.9 12.4 4.6 7.3 2.9 6.0 3.2 3.1 3.5 5.8 10.8 14.9 32.6 4.4 1.5 14.2 3.5 5.5 12.0 7.7 13.3 2.7 10.1 0.0 0.0 25.5 0.0 11.1 23.0 0.1 10.2 17.9 2.5 1.5 0.0 2.6 3.6 0.5 26.7 7.5 0.1 0.0 2.2 3.7 0.0 0.0 5.7 5.1 0.4 8.1 19.1 0.1 14.2 0.0 5.4 0.7 22.5 31.4 0.0 0.0 60.0 29.2 0.0 0.0 2.9 3.1 2.4 1.2 0.0 28.0 19.8 0.9 28.9 0.0 0.1 6.4 0.0 1.0 2.2 0.0 10.4 43.5 1.4 18.4 0.1 4.8 0.0 0.0 0.0 0.9 19.1 15.2 64.0 64.9 21.5 0.1 57.5 0.0 1.7 0.1 0.0 22.4 0.5 0.0 0.0 86.8 0.1 65.6 0.9 0.0 25.5 12.4 15.7 11.7 8.3 10.3 17.8 12.3 14.0 12.4 14.9 14.2 10.1 38.6 0.0 5.0 50.9 2.3 0.8 0.3 0.1 0.6 0.2 3.5 1.0 2.9 2.8 2.9 0.0 0.0 0.3 0.1 1.6 0.0 0.1 0.1 3.5 29.2 31.6 0.0 1.3 0.2 0.2 0.2 11.5 1.5 6.8 15.8 1.2 62.8 1.9 38.2 0.0 0.2 2.0 0.0 106.0 8.6 0.4 0.0 64.5 1.8 26.2 54.0 8.8 2.1 7.5 0.3 0.5 6.1 0.0 0.1 0.1 0.0 0.4 3.7 1.3 6.6 5.5 4.5 0.1 0.3 0.3 0.0 0.8 0.9 3.1 1.2 3.3 TM4SF20 "FLJ22800, TCCE518" ENSG00000168955 "Transmembrane 4 L six family member 20" Q53R12 2 227362038-227381995 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "intestine: 266.6" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 703.0" "Group enriched" "Detected in many" 6 "colorectal cancer: 5.0;liver cancer: 4.7;pancreatic cancer: 5.5;stomach cancer: 11.8" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.6;RPMI-8226: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051838, HPA063184, HPA065531" Uncertain Supported "Plasma membrane,Focal adhesion sites" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 56: Intestine - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Focal adhesion sites" "HPA051838: AB_2681631, HPA063184: AB_2684958, HPA065531: AB_2685506" "unprognostic (4.68e-2)" "unprognostic (1.13e-1)" "unprognostic (8.75e-2)" "unprognostic (4.96e-2)" "unprognostic (2.84e-2)" "unprognostic (1.63e-1)" "unprognostic (2.51e-1)" "unprognostic (2.36e-1)" "unprognostic (2.95e-1)" "unprognostic (1.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.44e-3)" "unprognostic (7.76e-2)" "unprognostic (2.60e-2)" "unprognostic (3.04e-3)" 0.1 0.1 0.2 0.3 0.2 0.2 0.0 1.2 0.4 0.0 0.4 3.1 266.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 3.9 0.3 0.0 0.0 0.0 0.3 144.5 1.6 0.0 0.1 0.5 3.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 2.6 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.1 0.2 0.6 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.2 1.2 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 48.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 21.4 0.0 0.0 0.0 77.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.0 0.5 0.0 157.9 0.7 0.0 0.0 703.0 0.0 0.0 0.3 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 18.8 0.0 TMCO5A "MGC35118, TMCO5" ENSG00000166069 "Transmembrane and coiled-coil domains 5A" Q8N6Q1 15 37921939-37967724 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 141 "testis: 90.7" "Group enriched" "Detected in some" 104 "Early spermatids: 1153.9;Late spermatids: 3910.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA056530, HPA064017" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA056530: AB_2683167, HPA064017: " "unprognostic (2.60e-1)" "unprognostic (1.69e-4)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 90.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1153.9 0.2 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3910.6 13.4 1.1 0.0 0.0 0.0 0.0 0.0 1.0 1.4 0.0 0.0 10.9 0.0 0.0 0.0 0.0 1.1 0.0 6.6 0.0 0.0 24.2 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 TMEM107 "JBTS29, MGC10744, MKS13" ENSG00000179029 "Transmembrane protein 107" Q6UX40 17 8172457-8176399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 110.8;Respiratory ciliated cells: 164.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052555, HPA059653" Approved Approved "Nucleoplasm,Plasma membrane,Midbody ring" Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Plasma membrane" "Midbody ring" "HPA052555: AB_2681870, HPA059653: AB_2684096" "unprognostic (2.87e-2)" "unprognostic (2.67e-1)" "unprognostic (2.85e-2)" "prognostic favorable (9.39e-5)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (5.70e-3)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (6.02e-3)" "unprognostic (1.83e-2)" "unprognostic (1.87e-1)" "unprognostic (2.66e-3)" "unprognostic (1.26e-1)" "unprognostic (4.99e-1)" "unprognostic (2.66e-1)" "unprognostic (1.49e-1)" 9.6 13.4 11.1 6.6 12.0 15.0 9.8 12.2 13.3 10.6 19.3 9.0 3.5 11.3 20.7 10.5 27.0 7.2 9.2 11.9 12.8 14.7 4.4 11.3 7.4 13.0 12.6 7.8 11.2 16.9 23.5 6.8 12.2 7.3 5.0 29.6 10.7 6.5 1.6 12.0 7.6 6.6 12.1 13.7 8.0 17.1 12.3 8.9 16.1 1.8 7.6 8.4 9.6 12.5 45.0 16.9 21.8 11.3 12.2 17.8 4.8 11.1 8.2 8.2 10.9 2.0 26.6 10.5 14.6 9.7 7.4 30.5 8.3 16.9 13.6 18.1 11.5 7.6 29.0 4.7 4.9 2.6 8.3 7.9 11.2 20.7 9.4 18.4 13.1 17.7 5.9 23.5 18.0 12.2 6.8 7.7 2.2 6.3 7.2 13.1 6.5 19.1 15.8 3.5 7.3 10.7 13.5 2.4 9.1 5.1 8.1 8.8 10.6 4.8 9.6 7.6 6.1 9.5 5.5 4.9 27.3 10.0 8.7 21.0 22.1 51.6 28.2 27.9 24.3 45.4 27.6 30.3 19.7 59.2 30.9 32.2 20.0 26.4 56.8 31.6 24.8 21.0 11.1 12.0 12.2 13.3 11.9 12.8 13.0 12.6 12.2 12.1 12.3 12.5 30.8 9.6 9.8 2.9 38.1 19.2 19.5 35.2 11.4 17.3 31.1 43.3 7.9 35.8 25.1 33.1 45.9 17.3 30.0 12.9 13.7 21.7 12.2 99.9 22.9 25.1 9.1 15.4 5.1 11.1 21.3 18.2 48.9 26.9 36.7 12.7 27.1 24.0 45.5 11.8 3.6 14.1 16.2 45.6 31.6 10.1 12.8 55.9 33.8 3.7 22.0 37.7 28.8 1.5 1.7 11.0 12.7 15.1 110.8 16.3 26.0 21.7 164.3 63.2 0.0 15.3 16.8 69.4 50.3 13.0 28.6 13.3 34.8 13.2 17.6 11.1 TMEM266 "C15orf27, FLJ38190" ENSG00000169758 "Transmembrane protein 266" Q2M3C6 15 76059958-76229121 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 8.4;skeletal muscle: 5.8;tongue: 2.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 10.4;Cytotrophoblasts: 16.0;Early spermatids: 7.0;Late spermatids: 19.7;Rod photoreceptor cells: 9.1;Sertoli cells: 6.6;Spermatogonia: 6.3" "Cancer enhanced" "Detected in some" "testis cancer: 2.3" "Region enriched" "Detected in many" 5 "cerebellum: 8.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.3" "Region enriched" "Detected in all" 6 "cerebellum: 58.7" "Region enriched" "Detected in many" 5 "cerebellum: 26.8" "HPA041921, HPA049425" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA041921: AB_10796789, HPA049425: AB_2732552" "unprognostic (8.63e-3)" "unprognostic (6.11e-3)" "unprognostic (3.44e-3)" "unprognostic (9.17e-5)" "unprognostic (4.67e-1)" "unprognostic (2.61e-2)" "unprognostic (9.34e-3)" "unprognostic (5.61e-2)" "unprognostic (8.48e-3)" "unprognostic (2.89e-2)" "unprognostic (1.18e-2)" "unprognostic (3.95e-2)" "unprognostic (1.68e-3)" "unprognostic (1.25e-1)" "unprognostic (1.31e-1)" "unprognostic (1.13e-2)" "unprognostic (7.86e-2)" 0.0 0.9 0.9 0.0 1.0 0.0 0.1 8.4 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.5 0.0 0.5 0.1 0.6 0.8 0.0 1.1 0.0 1.2 0.9 0.7 0.1 0.0 1.1 0.0 0.0 5.8 0.5 0.0 0.0 0.5 0.1 0.0 0.6 1.4 0.3 0.0 2.2 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 8.4 1.7 1.2 0.9 0.6 0.8 0.7 0.5 1.4 0.8 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 4.3 0.5 0.5 0.0 0.0 0.0 1.8 10.4 16.0 0.0 0.0 1.9 0.0 7.0 0.2 0.1 0.4 0.0 0.0 0.0 0.2 2.2 0.9 1.5 0.1 0.0 0.2 0.4 0.4 4.5 1.7 0.0 0.0 0.0 0.3 0.0 19.7 0.0 0.4 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.1 0.0 0.7 0.0 1.0 0.0 0.7 1.5 9.1 6.6 1.3 0.2 0.5 6.3 0.0 0.0 5.9 0.2 0.5 0.0 0.7 TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 280.4;stomach 1: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.8;Gastric mucus-secreting cells: 155.4;Paneth cells: 368.3;Prostatic glandular cells: 203.4;Proximal enterocytes: 159.6;Urothelial cells: 166.6" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 22.8;MCF7: 10.5;OE19: 35.9;RT4: 57.8;SK-BR-3: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" 0.6 0.2 0.4 13.9 0.4 0.1 20.1 0.2 0.4 5.0 3.1 104.0 78.5 1.0 2.8 36.1 10.7 24.1 0.2 0.3 0.3 47.7 33.5 39.9 0.2 0.4 0.3 0.2 111.4 4.0 1.5 0.2 0.3 280.4 78.0 0.2 76.2 7.7 0.1 7.3 89.6 3.3 0.1 0.2 146.2 1.5 0.3 0.8 19.2 0.1 10.2 35.7 7.6 0.5 0.1 0.0 0.1 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.1 22.8 3.3 0.1 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 3.7 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 10.5 0.3 1.0 2.3 35.9 0.2 0.1 0.0 2.6 1.3 57.8 0.2 0.7 0.3 11.7 0.3 0.4 8.8 0.0 0.0 0.1 0.6 0.6 0.1 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.4 0.3 0.3 0.4 0.3 0.3 0.1 0.3 0.5 0.1 51.3 109.8 0.0 1.7 0.3 30.9 6.8 0.0 0.0 34.0 25.8 0.6 32.9 42.1 47.8 0.0 0.7 1.1 404.8 23.5 39.2 21.3 7.4 0.5 1.3 18.0 2.7 0.2 60.4 0.1 1.0 155.4 5.8 7.0 0.0 0.4 32.0 0.1 0.0 0.1 84.1 44.7 0.3 0.3 4.8 0.0 2.0 10.6 0.0 0.6 0.0 0.0 0.0 0.0 65.1 368.3 0.0 0.0 203.4 159.6 3.8 36.6 0.0 0.0 1.6 2.0 0.4 1.4 2.1 0.1 0.3 1.1 0.0 105.7 166.6 TNFRSF11A "CD265, FEO, LOH18CR1, PDB2, RANK" ENSG00000141655 "TNF receptor superfamily member 11a" Q9Y6Q6 18 62325287-62391288 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.5;salivary gland: 25.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.6;Intestinal goblet cells: 24.0;Paneth cells: 42.3;Proximal enterocytes: 25.5;Undifferentiated cells: 42.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 5.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 5.3" "Cell line enriched" "Detected in many" 6 "HDLM-2: 125.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010391, HPA047976" Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 110000 "Cluster 48: NK-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "CAB010391: AB_2205352, HPA047976: AB_2680227" "unprognostic (4.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.23e-3)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (9.96e-4)" "unprognostic (4.24e-3)" "unprognostic (7.79e-4)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (4.69e-5)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (4.02e-2)" "unprognostic (7.07e-2)" 1.8 1.1 0.8 5.7 1.6 0.4 4.1 0.1 1.9 1.4 0.3 17.1 30.5 0.9 0.3 2.8 0.9 7.6 0.6 2.0 1.1 0.4 0.6 1.0 1.2 0.7 1.1 0.4 1.7 0.9 6.8 3.2 0.2 1.3 17.6 0.2 25.4 2.7 0.3 2.7 18.6 1.7 0.7 0.8 5.5 0.9 1.2 1.0 1.2 0.1 1.9 1.6 1.6 2.1 3.2 2.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 1.6 0.4 0.6 0.0 3.5 0.4 1.4 2.2 8.3 0.9 0.2 125.9 5.4 0.0 1.3 1.7 0.0 0.5 1.3 0.2 0.4 0.8 3.1 4.2 3.1 0.3 0.0 0.0 0.0 1.1 0.0 0.1 5.9 7.0 19.3 0.4 0.0 0.6 1.5 1.5 20.4 0.7 0.6 3.0 0.1 0.8 1.3 0.4 2.0 0.0 0.1 0.1 0.0 1.2 0.0 0.1 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.3 0.6 0.0 0.8 1.6 0.1 1.9 2.0 1.1 0.7 1.1 0.2 0.7 1.2 2.1 0.4 0.0 2.2 0.0 0.4 1.3 3.8 1.1 0.6 0.6 4.5 3.3 1.3 8.6 2.3 0.0 0.0 0.1 3.3 35.6 0.0 8.3 0.3 3.2 0.5 5.3 10.8 0.0 4.0 7.5 0.6 0.7 11.7 6.2 0.0 2.0 7.1 0.3 15.5 3.3 0.2 24.0 0.0 17.0 2.4 0.4 0.6 7.7 1.8 8.4 19.7 0.0 3.1 0.5 0.4 14.7 42.3 0.0 0.5 2.8 25.5 0.0 3.8 0.2 0.0 0.5 0.4 0.8 1.9 1.7 2.3 0.1 0.7 0.0 42.2 4.4 TNFRSF21 "CD358, DR6" ENSG00000146072 "TNF receptor superfamily member 21" O75509 6 47231532-47309905 "CD markers, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Apoptosis, Host-virus interaction, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 148.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 179.9;Prostatic glandular cells: 180.8;Syncytiotrophoblasts: 178.7;Urothelial cells: 387.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 35 "plasmacytoid DC: 69.2" "Lineage enriched" "Detected in single" 303 "dendritic cells: 69.2" "Cell line enhanced" "Detected in many" "OE19: 208.0;RT4: 523.8;SuSa: 213.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006746, CAB009805" Approved Supported "Plasma membrane,Cytosol" NA NA 2300000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "CAB009805: AB_2206956, HPA006746: AB_1078701" "unprognostic (1.19e-2)" "unprognostic (2.70e-1)" "unprognostic (3.26e-1)" "unprognostic (7.85e-2)" "unprognostic (1.44e-1)" "unprognostic (3.41e-2)" "unprognostic (9.80e-3)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (7.53e-2)" "unprognostic (1.38e-3)" "unprognostic (1.74e-1)" "prognostic favorable (7.23e-6)" "unprognostic (1.48e-1)" "unprognostic (1.34e-1)" "unprognostic (9.78e-2)" "unprognostic (1.45e-2)" 55.7 6.6 17.6 17.7 31.0 13.4 13.4 48.9 31.4 17.5 1.1 38.1 12.3 17.1 2.5 41.3 16.4 35.7 9.8 21.8 27.4 49.6 8.9 16.9 17.2 76.8 43.8 6.5 20.0 58.8 6.5 33.2 56.9 13.7 34.8 4.1 25.6 4.0 6.0 4.0 19.2 15.7 43.7 14.9 60.8 8.1 49.0 26.8 4.0 14.1 32.9 148.1 17.1 100.1 156.6 50.0 47.7 15.3 127.4 37.5 53.9 17.9 34.9 5.5 2.1 86.7 107.7 11.6 70.3 13.1 101.8 92.2 7.2 66.1 3.1 0.2 15.1 0.1 6.4 88.2 74.6 2.5 0.6 67.1 77.2 3.3 58.1 4.2 25.8 10.1 3.8 0.1 1.9 30.8 13.9 1.4 37.5 208.0 50.8 29.1 14.7 17.1 90.8 523.8 34.1 7.5 15.6 14.4 12.9 213.0 11.1 11.0 5.2 14.1 12.9 0.5 16.5 0.1 0.2 16.1 23.1 11.1 40.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.1 0.1 0.1 69.2 0.0 0.6 17.6 31.0 48.9 31.4 21.8 27.4 76.8 43.8 56.9 43.7 49.0 100.1 5.5 0.0 9.8 1.6 3.1 23.7 179.9 140.5 64.9 1.1 8.0 10.8 10.2 35.8 59.9 1.8 0.0 31.0 77.3 100.7 15.6 86.8 55.0 12.0 17.3 8.6 12.0 3.0 46.6 29.6 21.4 32.9 80.5 13.8 19.7 2.1 1.1 0.3 22.4 0.0 29.6 42.9 107.8 53.6 12.5 40.3 2.8 22.6 12.4 13.1 0.6 5.4 0.0 53.3 44.7 89.1 54.5 1.2 2.0 180.8 14.7 51.3 54.7 1.4 78.9 21.5 24.2 1.0 3.7 40.4 9.9 178.7 2.8 13.1 19.9 387.3 TNFRSF8 "CD30, D1S166E, KI-1" ENSG00000120949 "TNF receptor superfamily member 8" P28908 1 12063303-12144207 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.3" "Cell type enhanced" "Detected in some" "Adipocytes: 7.1;Early spermatids: 3.5;Kupffer cells: 5.3;Langerhans cells: 3.3;Late spermatids: 9.8;Macrophages: 5.8;monocytes: 5.1" "Cancer enriched" "Detected in some" 12 "testis cancer: 9.3" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Group enriched" "Detected in many" 4 "intermediate monocyte: 59.4;non-classical monocyte: 96.6" "Lineage enriched" "Detected in many" 5 "monocytes: 96.6" "Cell line enriched" "Detected in some" 21 "HDLM-2: 552.9" "Region enhanced" "Detected in many" "hypothalamus: 5.5" "CAB000016, HPA014823, HPA032081, HPA032082" Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "CAB000016: AB_563546, HPA014823: , HPA032081: AB_2674141, HPA032082: AB_2674142" "unprognostic (1.07e-2)" "unprognostic (2.06e-2)" "unprognostic (2.52e-2)" "unprognostic (5.98e-2)" "unprognostic (2.50e-1)" "unprognostic (1.46e-3)" "unprognostic (2.19e-1)" "unprognostic (3.93e-2)" "unprognostic (1.18e-1)" "unprognostic (9.18e-3)" "unprognostic (1.86e-1)" "unprognostic (2.06e-1)" "unprognostic (3.17e-8)" "unprognostic (3.31e-1)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (2.31e-2)" 5.3 0.0 0.1 3.1 2.3 0.6 3.5 0.0 0.6 0.2 0.1 0.4 0.0 0.8 0.0 0.2 0.9 0.6 1.9 0.0 0.2 0.3 0.0 0.9 1.2 0.2 0.1 0.2 0.1 0.0 0.0 0.7 0.2 0.2 0.1 0.0 0.3 0.1 0.9 0.9 0.7 0.5 0.1 1.4 2.5 1.4 0.7 1.0 0.1 1.2 1.1 0.9 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.4 0.0 0.1 0.8 11.7 0.0 0.0 0.0 0.0 0.0 0.1 552.9 0.1 0.0 0.1 0.0 0.0 10.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 3.7 26.3 1.5 0.0 0.0 1.5 0.2 21.7 0.0 0.4 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.1 0.0 1.4 1.4 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 17.6 1.0 0.1 59.4 0.3 0.1 0.1 0.0 8.7 0.0 0.0 0.0 18.3 0.0 96.6 2.3 0.8 8.5 0.1 2.3 0.0 0.6 0.0 0.2 0.2 0.1 0.2 0.1 0.7 0.2 7.1 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.5 0.1 0.5 2.2 0.0 0.0 0.6 0.0 0.2 1.1 2.6 0.1 0.0 0.1 2.2 0.1 1.5 0.0 0.5 0.0 0.0 5.3 3.3 9.8 0.3 5.8 0.0 1.0 5.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.3 1.0 0.0 0.1 0.3 0.4 0.2 0.0 0.1 TNFSF13B "BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20" ENSG00000102524 "TNF superfamily member 13b" Q9Y275 13 108251240-108308484 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.5;Kupffer cells: 141.1;Langerhans cells: 246.7;Macrophages: 170.4;monocytes: 509.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 505.4" "Group enriched" "Detected in all" 11 "dendritic cells: 206.4;granulocytes: 505.4;monocytes: 350.9" "Cell line enriched" "Detected in some" 7 "U-937: 167.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009188, HPA030526" Enhanced Supported "Vesicles,Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 393000 790000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Vesicles, Focal adhesion sites" "CAB009188: , HPA030526: " "unprognostic (6.48e-2)" "unprognostic (3.05e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (2.61e-2)" "unprognostic (7.99e-2)" "unprognostic (8.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.63e-1)" "unprognostic (1.02e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.53e-11)" "unprognostic (1.23e-1)" "unprognostic (4.14e-2)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" 8.2 5.3 2.8 25.9 2.6 20.1 4.7 2.7 4.1 2.2 5.8 5.5 10.7 1.4 1.5 4.8 2.4 12.4 3.8 2.7 3.1 1.5 5.3 10.9 20.9 6.3 3.0 1.1 1.5 0.7 1.0 9.0 4.2 1.7 8.4 0.4 3.3 1.2 1.4 1.9 6.4 5.0 4.6 15.9 5.0 1.2 3.5 5.3 3.0 1.6 17.7 11.1 2.1 5.2 0.1 0.4 0.1 0.1 0.7 0.8 0.2 0.3 0.8 0.6 2.1 0.1 1.7 0.3 0.2 0.2 0.3 0.1 0.0 0.1 0.1 11.6 0.0 0.9 0.4 0.0 0.4 10.2 0.3 2.0 0.4 0.2 0.1 0.4 0.1 0.1 0.1 0.6 1.2 0.0 0.1 5.3 0.1 1.1 0.0 0.0 0.2 0.0 0.6 0.3 1.3 0.3 0.0 0.0 0.4 0.2 0.1 22.3 0.2 0.3 0.0 0.0 0.4 10.0 0.3 0.1 10.3 167.0 1.7 12.6 350.9 100.1 5.4 272.3 31.5 4.4 21.5 4.4 206.4 7.1 9.9 3.4 505.4 5.0 234.1 77.8 19.4 165.8 2.8 2.6 2.7 4.1 2.7 3.1 6.3 3.0 4.2 4.6 3.5 5.2 3.1 16.0 12.9 6.2 7.0 7.1 0.7 1.3 1.2 0.9 2.4 3.2 0.6 10.0 4.2 5.5 0.0 0.5 40.6 0.6 1.9 2.3 1.2 0.4 0.7 3.6 1.2 14.5 18.1 32.5 1.1 29.6 3.1 0.5 5.1 0.9 3.9 2.8 87.5 0.0 11.2 0.9 0.0 141.1 246.7 0.6 5.3 170.4 8.8 15.0 509.4 0.2 5.2 55.3 5.1 1.7 0.5 1.9 1.5 2.7 2.2 1.3 2.0 0.3 6.6 1.4 4.1 0.1 0.7 0.5 4.7 1.1 10.5 1.2 1.8 3.1 TNK2 "ACK, ACK1, p21cdc42Hs" ENSG00000061938 "Tyrosine kinase non receptor 2" Q07912 3 195863364-195911945 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 102.9" "Cell type enhanced" "Detected in many" "Horizontal cells: 99.3;Oligodendrocyte precursor cells: 245.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041954, HPA069561" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Vesicles "HPA041954: AB_10794164, HPA069561: " "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (1.15e-3)" "prognostic unfavorable (8.96e-4)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (8.89e-3)" "unprognostic (1.13e-1)" "unprognostic (8.92e-3)" "unprognostic (4.49e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (6.82e-2)" "unprognostic (9.76e-2)" "unprognostic (1.44e-1)" "prognostic favorable (1.00e-4)" 14.2 10.0 77.1 24.7 64.1 72.2 15.0 40.0 102.9 18.0 11.8 18.5 9.4 13.8 11.1 19.1 17.1 10.5 18.4 75.6 51.4 7.7 10.5 14.1 30.0 77.5 59.8 13.4 12.1 6.1 36.4 12.7 70.1 21.1 6.3 9.3 26.3 11.8 54.8 62.3 16.1 9.2 45.5 27.0 19.7 12.0 57.0 16.0 10.0 16.7 20.1 19.4 19.3 60.6 93.4 16.3 15.4 13.4 15.3 11.5 80.0 17.7 16.7 11.7 9.4 15.6 79.3 25.9 55.1 24.2 17.4 34.1 14.9 22.2 3.5 61.8 15.4 22.0 36.2 10.4 7.9 13.5 10.2 7.8 30.7 11.7 17.9 26.7 13.3 9.2 11.3 30.6 9.4 67.1 5.3 39.7 12.3 24.6 29.1 13.8 15.6 26.0 7.2 51.2 16.2 16.5 9.5 37.6 21.3 11.3 71.4 11.9 18.9 19.1 13.0 11.4 48.6 70.8 9.2 17.0 22.1 38.0 15.4 1.4 1.2 0.3 0.9 1.5 0.4 1.3 0.8 0.4 0.5 2.5 0.5 0.5 2.7 0.4 1.4 1.5 0.1 0.7 77.1 64.1 40.0 102.9 75.6 51.4 77.5 59.8 70.1 45.5 57.0 60.6 9.3 6.4 7.7 44.4 14.6 6.9 8.1 6.0 4.6 30.6 13.0 12.6 16.1 7.2 8.9 0.0 50.1 13.4 11.0 18.0 1.9 4.0 1.0 4.1 5.4 11.1 6.1 12.8 42.7 5.3 3.3 4.6 14.3 4.1 1.3 4.5 11.7 19.2 8.1 99.3 45.3 2.3 6.1 16.0 11.7 1.2 6.5 13.7 5.4 20.6 16.2 5.9 21.6 245.3 25.1 29.5 9.6 6.4 10.7 8.2 0.9 1.6 7.6 20.3 0.0 4.8 5.7 6.4 11.2 11.0 10.5 4.2 12.5 1.7 6.4 19.0 TRAIP "RNF206, TRIP" ENSG00000183763 "TRAF interacting protein" Q9BWF2 3 49828601-49856574 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 8.2;Spermatocytes: 15.6;Spermatogonia: 9.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 10.8" "HPA036261, HPA036262" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA036261: AB_10673348, HPA036262: AB_2675029" "unprognostic (5.30e-3)" "unprognostic (9.41e-2)" "unprognostic (1.48e-1)" "unprognostic (6.50e-3)" "unprognostic (1.88e-1)" "unprognostic (7.68e-3)" "prognostic unfavorable (8.77e-5)" "unprognostic (4.61e-2)" "unprognostic (1.52e-2)" "unprognostic (8.61e-2)" "unprognostic (1.24e-2)" "unprognostic (7.97e-2)" "unprognostic (9.01e-5)" "unprognostic (5.84e-2)" "unprognostic (4.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.24e-1)" 1.5 1.0 1.6 1.8 2.5 6.8 1.9 0.7 1.8 2.0 0.4 2.3 1.5 1.7 1.4 2.9 1.8 1.0 0.9 1.6 0.9 0.8 0.8 0.9 4.6 0.6 0.6 2.1 1.0 0.8 1.2 1.6 0.7 1.4 2.9 2.3 1.2 0.9 2.0 4.2 2.0 2.1 0.6 1.9 1.2 7.9 1.3 5.3 1.4 1.2 4.4 1.3 1.9 0.9 10.4 12.4 17.4 17.6 1.6 2.4 14.4 12.4 5.8 25.3 24.0 15.2 11.6 25.5 8.5 7.1 17.7 13.4 18.5 14.0 18.8 14.7 12.2 19.2 16.3 13.6 0.7 15.8 15.4 1.6 2.0 20.4 10.7 3.0 6.7 22.3 14.0 17.8 11.4 15.1 26.5 20.1 14.0 12.3 20.3 14.4 11.7 14.8 4.6 14.2 8.4 14.4 13.6 11.3 8.8 12.4 10.2 22.4 5.2 16.1 19.0 22.5 24.4 13.0 33.7 27.3 8.1 21.2 14.6 0.0 0.6 0.3 0.9 0.3 0.9 2.9 0.5 2.1 0.6 1.5 0.7 1.1 0.1 1.2 1.3 0.7 0.3 0.6 1.6 2.5 0.7 1.8 1.6 0.9 0.6 0.6 0.7 0.6 1.3 0.9 0.6 3.2 0.6 1.0 1.8 1.1 0.6 1.5 2.2 2.8 1.2 1.4 2.6 0.0 0.3 3.7 0.0 4.2 1.2 1.8 0.0 2.0 4.3 0.6 0.9 0.8 0.0 3.8 1.4 1.0 8.2 2.0 1.5 0.9 0.0 5.7 1.1 0.7 3.5 0.0 0.9 2.0 0.0 0.8 0.4 4.8 2.5 0.7 1.8 1.0 1.8 1.7 0.0 0.5 0.6 1.1 0.3 1.2 4.3 0.8 0.9 0.3 0.5 3.3 0.0 1.4 1.7 15.6 9.1 2.3 0.3 1.0 1.2 1.2 4.6 0.2 TREML1 "dJ238O23.3, TLT1" ENSG00000161911 "Triggering receptor expressed on myeloid cells like 1" Q86YW5 6 41149342-41154337 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.7;brain: 4.5;lymphoid tissue: 7.3" "Group enriched" "Detected in some" 7 "Macrophages: 75.6;monocytes: 28.3" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 92.4" "Lineage enriched" "Detected in many" 49 "granulocytes: 92.4" "Cell line enriched" "Detected in single" 170 "HEL: 66.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016700, HPA017860" Enhanced Uncertain "Nuclear speckles,Golgi apparatus,Plasma membrane,Cytosol" NA NA 43000000 "Cluster 34: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Nuclear speckles, Cytosol" "Golgi apparatus, Plasma membrane" "HPA016700: AB_1858262, HPA017860: AB_1858261" "unprognostic (6.70e-2)" "unprognostic (3.50e-3)" "unprognostic (1.15e-3)" "unprognostic (1.62e-1)" "unprognostic (3.48e-2)" "unprognostic (4.53e-5)" "unprognostic (1.10e-2)" "unprognostic (2.55e-3)" "unprognostic (4.50e-1)" "unprognostic (2.12e-3)" "unprognostic (2.34e-2)" "unprognostic (7.04e-2)" "unprognostic (1.11e-4)" "unprognostic (1.36e-1)" "unprognostic (8.38e-2)" "unprognostic (7.51e-2)" "unprognostic (3.41e-2)" 0.9 1.0 1.7 2.7 2.1 8.7 0.5 2.2 4.5 0.3 1.3 0.3 0.0 0.1 0.4 0.1 0.4 0.9 0.3 1.9 2.5 0.2 0.3 2.1 5.4 3.3 2.4 0.1 0.4 0.2 0.4 0.5 2.8 0.2 0.9 0.2 0.4 0.3 0.1 0.3 0.4 0.2 2.5 7.3 0.2 0.1 3.6 4.1 0.3 0.5 4.8 0.4 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 66.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 92.4 1.7 2.8 0.2 1.8 0.4 0.2 0.1 0.0 0.7 0.3 0.5 0.0 10.7 0.0 0.3 0.9 0.0 110.6 1.7 2.1 2.2 4.5 1.9 2.5 3.3 2.4 2.8 2.5 3.6 3.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 3.9 0.0 3.9 0.0 0.0 0.0 0.0 1.6 2.7 0.0 0.0 75.6 0.0 6.5 28.3 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 TRPM4 FLJ20041 ENSG00000130529 "Transient receptor potential cation channel subfamily M member 4" Q8TD43 19 49157741-49211836 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 179.2;Hepatocytes: 81.7;Intestinal goblet cells: 114.8;Paneth cells: 77.1;Undifferentiated cells: 88.9" "Cancer enriched" "Detected in all" 4 "prostate cancer: 85.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 3.3;granulocytes: 2.8;monocytes: 4.3" "Cell line enhanced" "Detected in many" "OE19: 32.7;RT4: 60.8;SK-BR-3: 38.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041169 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA041169: AB_2677343" "unprognostic (8.20e-3)" "unprognostic (1.41e-1)" "unprognostic (7.86e-2)" "prognostic favorable (2.88e-7)" "unprognostic (1.62e-2)" "unprognostic (9.78e-2)" "unprognostic (1.77e-2)" "unprognostic (2.90e-1)" "unprognostic (3.33e-2)" "unprognostic (3.38e-2)" "unprognostic (2.94e-2)" "unprognostic (2.79e-1)" "prognostic favorable (2.53e-7)" "unprognostic (8.46e-3)" "unprognostic (2.16e-1)" "unprognostic (5.70e-2)" "unprognostic (1.00e-2)" 10.8 6.1 5.8 6.1 5.4 4.6 13.5 8.5 7.0 11.5 4.8 46.1 25.3 9.9 2.5 13.1 9.2 7.4 23.0 5.9 4.5 22.8 15.4 16.0 1.8 6.2 7.4 3.3 10.1 3.7 5.6 5.3 6.9 35.7 12.9 1.3 27.3 6.2 14.0 26.6 22.9 3.4 4.2 5.5 20.6 5.4 6.6 1.0 17.3 5.3 1.9 13.7 14.4 5.1 11.9 9.0 2.1 9.5 7.7 6.6 6.6 10.0 6.0 2.7 3.7 6.1 18.7 0.4 2.7 6.8 3.6 15.7 1.3 3.0 1.0 0.2 3.4 1.9 4.0 3.7 6.6 0.3 11.7 9.3 13.6 5.3 2.6 3.3 4.6 1.0 4.9 2.1 6.9 17.4 0.8 0.9 1.0 32.7 13.3 4.1 2.0 0.6 4.6 60.8 0.8 2.2 4.1 38.6 2.2 0.7 22.6 3.7 11.8 14.4 7.8 7.9 0.2 3.9 4.3 0.4 7.9 7.4 5.3 2.2 4.3 0.7 0.3 2.5 0.2 0.5 0.2 0.2 3.3 0.5 0.3 0.3 2.8 0.5 1.0 3.1 0.2 1.4 5.8 5.4 8.5 7.0 5.9 4.5 6.2 7.4 6.9 4.2 6.6 5.1 12.8 32.1 2.6 9.8 3.5 12.5 15.3 9.9 9.1 2.0 19.0 14.6 16.7 17.2 12.3 14.7 0.0 6.6 0.2 179.2 19.6 7.9 2.9 17.5 8.2 11.7 21.7 0.0 5.4 18.5 6.8 6.0 71.4 36.2 5.7 2.9 11.4 81.7 19.9 0.0 8.5 114.8 14.2 9.8 19.0 3.1 6.8 8.5 39.2 9.4 12.8 6.7 0.0 3.5 0.9 32.9 77.1 7.2 7.6 35.5 55.3 3.8 8.9 2.6 32.9 2.2 8.5 6.1 15.7 8.4 11.5 3.4 1.9 4.1 88.9 33.1 TRPV2 "VRL, VRL-1, VRL1" ENSG00000187688 "Transient receptor potential cation channel subfamily V member 2" Q9Y5S1 17 16415571-16437003 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 50.0;Hofbauer cells: 50.6;monocytes: 39.4;NK-cells: 49.4" "Cancer enriched" "Detected in all" 8 "melanoma: 59.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 78.8;fHDF/TERT166: 108.4;HMC-1: 89.0;SK-MEL-30: 94.7;TIME: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA044993 Uncertain Supported "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA044993: AB_10960889" "unprognostic (1.57e-1)" "unprognostic (4.34e-3)" "unprognostic (2.05e-2)" "unprognostic (1.58e-2)" "unprognostic (2.85e-2)" "unprognostic (6.16e-3)" "unprognostic (5.25e-2)" "unprognostic (1.25e-1)" "unprognostic (8.40e-3)" "unprognostic (2.43e-1)" "unprognostic (3.11e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.19e-6)" "unprognostic (7.94e-2)" "prognostic unfavorable (5.53e-4)" "unprognostic (8.07e-2)" "unprognostic (1.23e-1)" 17.1 20.5 6.2 18.3 8.0 22.8 10.4 5.7 7.6 7.9 3.9 7.0 6.6 7.6 1.8 5.3 7.3 8.5 11.2 6.1 9.8 4.7 4.0 30.2 24.6 10.6 15.4 7.8 6.3 8.9 1.6 20.1 17.2 6.0 6.2 1.0 4.5 2.6 3.9 6.5 10.7 11.8 7.1 23.7 5.9 2.0 7.3 15.7 6.2 5.5 16.2 10.7 7.2 8.0 0.3 1.6 0.0 0.0 25.6 78.8 4.9 8.3 9.4 9.1 8.9 0.3 0.3 9.6 2.2 108.4 7.8 0.2 0.2 0.0 5.1 43.0 0.7 10.7 0.0 26.1 30.0 14.8 89.0 35.2 0.0 54.0 0.7 4.1 3.8 12.9 37.2 26.0 43.4 0.5 19.1 20.5 0.1 0.1 0.2 11.3 0.3 4.3 40.6 1.1 1.2 0.1 0.0 0.0 94.7 41.0 0.0 12.7 84.9 0.2 0.3 0.3 1.1 0.1 0.3 5.1 8.2 21.6 12.6 60.8 26.6 35.8 63.4 52.8 55.5 19.2 46.0 59.3 58.7 20.3 25.7 44.8 6.8 63.2 49.4 51.3 49.9 43.1 6.2 8.0 5.7 7.6 6.1 9.8 10.6 15.4 17.2 7.1 7.3 8.0 15.8 0.0 5.3 1.0 11.1 2.8 0.1 0.0 0.0 0.6 0.5 0.4 1.1 1.5 0.6 0.0 0.0 2.2 29.3 0.0 0.0 0.2 0.3 0.4 0.1 12.3 0.0 6.7 3.3 3.6 2.3 11.0 1.1 0.1 50.0 16.7 8.9 0.4 50.6 0.0 2.6 0.0 0.0 19.5 18.2 0.0 1.8 28.7 28.4 4.7 39.4 0.3 49.4 0.5 0.5 4.7 0.1 4.5 15.1 0.0 0.0 0.1 0.8 0.6 26.3 7.9 23.6 1.3 5.9 0.4 1.7 16.1 26.8 2.8 0.0 0.1 TSPAN15 "NET-7, TM4SF15" ENSG00000099282 "Tetraspanin 15" O95858 10 69451465-69507666 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 125.8;Ductal cells: 125.2;Exocrine glandular cells: 189.3;Pancreatic endocrine cells: 193.4;Paneth cells: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in many" 6 "T-cells: 19.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 154.7;EFO-21: 211.3;MCF7: 168.0;OE19: 153.2;PC-3: 266.8;SK-BR-3: 134.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044657, HPA071160" Approved Approved "Nuclear bodies,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Nuclear bodies, Plasma membrane" "Vesicles, Cytosol" "HPA044657: AB_10967927, HPA071160: " "unprognostic (2.03e-1)" "unprognostic (1.28e-1)" "unprognostic (1.43e-1)" "unprognostic (1.48e-2)" "unprognostic (9.44e-3)" "unprognostic (6.81e-3)" "prognostic unfavorable (8.00e-4)" "unprognostic (2.23e-1)" "unprognostic (3.65e-1)" "unprognostic (2.76e-1)" "unprognostic (8.22e-3)" "unprognostic (2.36e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (8.49e-2)" "unprognostic (4.66e-2)" "unprognostic (6.34e-2)" "unprognostic (3.78e-3)" 70.1 5.3 22.8 15.3 37.6 1.0 61.0 35.0 34.1 16.4 14.9 62.5 38.8 32.6 8.5 10.8 24.6 27.4 16.9 23.6 25.4 25.9 4.6 34.4 8.7 36.9 33.4 3.4 20.0 3.2 6.6 28.1 33.7 34.5 39.4 3.1 26.6 24.7 17.9 10.6 38.8 31.3 30.0 26.7 75.3 9.5 34.5 3.6 14.5 5.6 7.5 46.0 14.9 62.4 51.3 103.9 2.1 0.3 2.3 0.0 12.0 0.2 1.9 2.6 6.8 45.1 154.7 0.0 211.3 2.3 9.2 101.2 7.2 11.5 3.0 42.1 20.4 2.9 3.5 10.0 1.1 0.1 1.8 2.2 3.1 1.4 1.5 7.5 39.4 20.5 1.1 0.0 1.2 168.0 0.6 0.9 2.6 153.2 266.8 4.0 2.1 2.0 29.7 92.9 34.5 13.2 0.6 134.8 17.9 17.3 59.3 2.2 34.5 0.2 0.8 0.1 17.5 1.2 6.1 1.0 1.1 0.1 0.2 0.0 0.0 0.0 2.3 0.0 19.5 0.0 3.1 2.8 3.3 0.0 1.0 0.2 0.0 0.1 0.0 0.2 1.1 0.5 22.8 37.6 35.0 34.1 23.6 25.4 36.9 33.4 33.7 30.0 34.5 62.4 108.8 32.1 6.9 4.9 1.5 3.6 10.9 59.6 2.2 2.9 45.1 15.6 1.7 31.5 29.5 29.5 6.2 2.0 1.6 125.8 3.9 125.2 27.9 25.5 3.8 48.4 40.2 8.0 1.7 189.3 11.9 8.2 71.4 36.6 1.3 2.5 10.4 0.1 25.3 1.7 1.0 106.7 36.7 8.5 16.1 6.6 0.6 9.8 28.4 15.0 15.6 44.7 0.0 11.1 75.3 193.4 120.9 0.0 0.2 50.4 68.3 1.8 27.6 1.5 13.1 39.7 26.8 4.3 18.5 2.9 3.1 3.0 3.9 7.5 66.3 29.6 TTC17 FLJ10890 ENSG00000052841 "Tetratricopeptide repeat domain 17" Q96AE7 11 43358920-43494933 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038508 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Cytosol "HPA038508: AB_10671744" "unprognostic (2.71e-1)" "unprognostic (4.04e-3)" "unprognostic (6.48e-2)" "unprognostic (2.64e-1)" "unprognostic (1.17e-1)" "unprognostic (5.66e-2)" "unprognostic (1.74e-1)" "unprognostic (9.03e-2)" "unprognostic (5.01e-3)" "unprognostic (2.62e-1)" "unprognostic (1.34e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (4.75e-6)" "unprognostic (1.04e-2)" "unprognostic (4.40e-1)" "unprognostic (1.18e-1)" "unprognostic (1.54e-2)" 20.7 18.7 11.0 16.1 11.3 15.5 28.6 16.7 12.2 22.0 22.0 21.2 21.6 26.9 25.0 14.2 28.4 22.3 13.5 11.1 12.2 19.4 38.6 24.2 20.2 11.9 12.5 40.9 49.5 27.7 12.3 29.2 11.7 25.4 22.9 25.1 40.7 21.4 16.4 19.5 25.5 23.0 11.0 23.4 27.4 24.8 12.4 24.6 36.9 20.0 22.4 18.8 15.6 13.0 15.0 30.4 31.3 49.3 77.2 63.6 22.1 35.6 47.6 29.3 35.1 21.1 21.7 31.6 34.9 35.9 33.7 31.1 22.3 23.5 35.2 24.5 29.0 24.2 19.5 20.8 95.3 36.6 29.9 59.5 69.8 21.3 68.4 66.2 29.5 22.7 35.5 26.2 29.8 18.1 27.1 20.3 46.8 58.0 25.0 25.1 33.3 36.9 37.2 21.4 16.7 39.7 27.7 73.1 44.6 31.4 68.6 40.8 39.6 41.7 18.4 47.1 52.1 51.1 44.5 29.8 26.9 21.6 45.3 20.0 21.7 19.0 14.9 22.4 15.9 16.4 16.2 14.5 16.9 14.8 16.3 15.1 18.5 16.5 20.8 17.6 16.1 18.0 11.0 11.3 16.7 12.2 11.1 12.2 11.9 12.5 11.7 11.0 12.4 13.0 43.0 64.1 62.7 159.6 53.3 42.1 35.0 36.4 30.7 44.1 40.3 35.7 20.5 31.5 51.9 22.0 60.5 32.6 43.8 30.7 3.9 23.1 52.6 35.8 44.5 40.9 22.3 44.0 204.6 43.4 28.8 44.4 40.2 48.6 36.6 56.2 40.0 57.5 26.2 47.1 203.2 42.1 34.6 48.0 32.3 18.4 57.2 37.1 28.4 181.8 47.8 24.8 37.0 192.0 200.6 29.7 31.5 36.5 48.9 50.1 47.7 15.5 54.3 47.3 52.6 45.5 36.2 51.8 35.0 34.6 43.2 30.8 45.6 33.5 35.8 42.7 TTLL5 KIAA0998 ENSG00000119685 "Tubulin tyrosine ligase like 5" Q6EMB2 14 75633625-75955079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transcription Ligase "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 57.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 127.2;Early spermatids: 111.0;Excitatory neurons: 134.3;Inhibitory neurons: 114.2;Oligodendrocytes: 242.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032128 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA032128: AB_10600835" "unprognostic (7.35e-2)" "unprognostic (7.29e-2)" "unprognostic (7.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (5.96e-2)" "unprognostic (7.21e-5)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (7.93e-2)" "unprognostic (1.10e-2)" "unprognostic (3.43e-1)" "unprognostic (5.67e-3)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (8.97e-2)" "unprognostic (2.15e-2)" 5.5 5.5 3.7 6.0 6.0 11.7 7.1 7.1 7.2 7.3 15.0 6.2 4.7 8.0 7.2 7.8 11.6 6.5 5.8 3.8 6.6 6.2 4.1 6.5 5.1 10.5 6.4 7.1 4.9 11.1 5.4 7.5 10.6 6.9 7.3 23.9 6.5 6.9 4.7 7.1 4.5 8.6 6.4 4.1 5.9 57.4 6.4 10.1 7.8 5.8 7.5 6.1 6.4 12.0 22.8 16.2 13.9 14.5 10.9 16.8 12.9 13.1 15.9 15.4 19.9 10.3 20.8 6.4 7.2 13.9 11.3 21.3 12.3 21.7 29.3 7.6 7.3 12.5 16.8 11.3 9.3 9.2 11.5 13.1 10.6 19.4 21.5 16.8 33.8 17.5 7.2 10.5 15.7 32.1 15.6 12.6 9.9 18.0 16.6 9.5 19.6 8.8 15.0 22.2 18.4 11.6 27.5 20.2 6.8 11.0 27.6 9.8 38.1 20.5 18.0 18.5 12.2 8.8 13.5 14.6 20.7 10.4 13.9 11.6 2.0 1.7 2.6 2.0 2.4 2.3 2.5 2.7 3.2 1.8 2.9 2.7 2.4 2.3 2.5 3.4 2.2 1.4 3.7 6.0 7.1 7.2 3.8 6.6 10.5 6.4 10.6 6.4 6.4 12.0 7.1 3.2 10.1 71.8 6.1 5.0 5.5 5.4 8.0 10.9 17.3 11.6 8.7 17.2 10.2 11.0 127.2 8.1 8.5 7.6 3.9 7.1 111.0 37.4 11.9 10.7 7.7 5.0 134.3 5.3 13.2 9.3 8.6 10.8 12.6 11.7 19.6 7.4 5.6 0.0 114.2 6.5 16.2 5.8 5.1 93.1 12.5 6.6 5.4 82.4 8.5 10.0 6.2 78.4 242.9 6.1 11.9 11.7 7.6 6.2 6.0 2.4 40.1 80.1 13.1 9.5 6.0 37.7 16.4 9.0 6.3 6.0 8.3 9.1 8.0 4.6 TULP3 TUBL3 ENSG00000078246 "TUB like protein 3" O75386 12 2877223-2941138 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015285, HPA018496" Uncertain Supported "Nucleoplasm,Nucleoli,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA015285: AB_1858460, HPA018496: AB_2669889" "unprognostic (5.33e-2)" "unprognostic (1.57e-1)" "unprognostic (4.80e-2)" "prognostic favorable (2.99e-4)" "unprognostic (2.45e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (7.97e-5)" "unprognostic (2.44e-1)" "unprognostic (4.09e-2)" "unprognostic (1.73e-1)" "unprognostic (1.50e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (7.18e-4)" "unprognostic (7.52e-2)" "unprognostic (1.94e-1)" "unprognostic (2.36e-2)" "unprognostic (3.19e-2)" 21.0 17.1 13.6 7.5 14.2 2.6 18.3 19.2 16.1 33.3 15.8 21.6 5.4 23.2 11.7 17.8 24.3 12.1 17.7 13.8 13.2 17.3 9.0 13.5 6.1 16.3 14.8 37.7 9.6 13.3 12.3 13.7 13.8 15.4 8.2 12.7 13.0 13.9 10.4 25.7 10.5 18.2 14.5 9.4 15.5 13.0 14.4 9.4 15.5 9.7 8.1 16.7 24.1 17.1 22.6 18.8 35.0 29.1 34.3 51.0 32.9 34.5 57.5 36.4 40.2 24.0 20.4 16.7 5.1 51.2 31.2 18.5 21.1 22.2 42.0 21.7 15.4 10.0 23.4 15.5 44.3 10.8 11.1 30.1 25.7 55.3 74.9 44.6 28.6 20.8 9.7 15.1 31.0 20.3 16.1 9.4 47.4 17.8 13.7 16.8 34.2 6.3 22.9 18.7 8.8 23.4 30.1 17.8 19.9 63.4 22.2 10.5 23.0 26.6 32.0 54.7 33.9 4.7 6.0 14.3 26.9 5.9 41.5 0.0 0.9 0.3 2.1 0.8 3.5 1.6 1.7 2.2 0.7 1.8 2.0 2.8 0.4 2.7 0.5 1.6 3.3 1.0 13.6 14.2 19.2 16.1 13.8 13.2 16.3 14.8 13.8 14.5 14.4 17.1 12.9 6.4 10.5 70.5 6.2 20.3 16.9 14.8 26.2 6.1 9.9 12.2 8.0 18.6 15.9 1.8 2.1 9.4 6.0 4.6 23.5 17.3 5.8 35.1 33.5 15.2 3.6 6.1 6.0 7.3 10.6 31.7 6.6 14.6 0.0 11.5 24.3 5.5 5.3 40.4 10.8 4.0 14.2 2.5 8.6 3.6 40.7 5.4 19.6 14.0 6.7 50.7 12.3 10.1 34.9 11.1 2.4 24.8 8.3 23.3 3.2 21.9 47.4 10.0 39.5 22.3 26.3 38.0 50.8 22.2 20.2 11.6 6.5 13.3 6.4 13.2 TXNDC11 EFP1 ENSG00000153066 "Thioredoxin domain containing 11" Q6PKC3 16 11679083-11742857 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Plasma cells: 307.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 141.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041174, HPA041390" Supported Supported "Plasma membrane,Cytosol" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 3: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane, Cytosol" "HPA041174: AB_10794191, HPA041390: AB_10796670" "unprognostic (1.96e-2)" "unprognostic (1.43e-1)" "unprognostic (6.82e-3)" "prognostic favorable (2.12e-5)" "prognostic unfavorable (1.36e-4)" "unprognostic (2.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.68e-3)" "unprognostic (4.90e-2)" "unprognostic (2.17e-1)" "unprognostic (1.08e-1)" "unprognostic (2.01e-1)" "unprognostic (2.35e-2)" "unprognostic (9.96e-2)" "unprognostic (8.30e-2)" "unprognostic (3.23e-2)" "unprognostic (2.34e-2)" 15.7 14.2 4.5 22.5 5.6 55.4 16.6 7.7 5.9 20.8 16.6 30.0 38.5 15.1 23.6 13.1 16.2 17.3 13.7 5.0 4.9 25.7 44.3 34.9 25.3 4.8 4.8 16.6 26.5 45.1 12.6 17.0 4.8 24.4 29.8 15.3 34.8 14.9 30.1 12.0 32.0 15.6 4.6 22.4 36.1 8.5 4.9 20.6 34.4 14.9 27.9 25.3 11.8 5.0 26.1 17.7 8.2 11.2 21.6 18.0 14.4 25.3 34.5 22.7 29.1 8.8 40.5 65.2 41.6 32.0 30.9 22.9 10.2 21.4 18.5 29.4 13.5 13.9 19.4 43.8 31.7 20.6 27.1 13.7 23.6 25.4 39.9 17.6 28.9 14.6 21.5 81.8 20.2 23.7 16.1 7.9 10.7 18.6 9.1 20.5 16.5 141.9 26.0 13.7 11.5 10.9 49.6 38.2 27.3 9.1 23.4 28.1 30.1 10.5 12.0 49.8 14.7 110.5 64.8 39.5 22.3 25.7 17.9 3.5 2.4 7.7 1.8 1.7 4.5 3.8 3.3 4.1 2.6 4.6 3.2 2.1 0.7 5.6 2.2 2.0 6.8 2.8 4.5 5.6 7.7 5.9 5.0 4.9 4.8 4.8 4.8 4.6 4.9 5.0 16.2 44.8 46.2 21.9 49.2 14.7 24.8 12.9 23.3 16.2 16.1 18.0 9.1 18.6 24.6 18.4 50.1 21.1 27.2 45.8 15.6 20.4 3.1 19.9 14.6 15.2 24.5 6.5 23.0 39.7 29.8 14.0 45.3 28.5 15.2 13.0 15.7 39.3 30.3 23.5 25.5 44.0 8.2 18.1 26.9 1.4 20.2 29.2 23.2 18.7 21.2 16.4 15.5 22.1 18.6 26.1 21.0 13.2 307.9 28.0 37.1 15.2 15.9 23.4 6.6 13.8 16.2 11.6 13.1 17.5 11.8 25.0 25.2 11.3 27.7 32.1 TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 596.8;lymphoid tissue: 423.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3777.1;Kupffer cells: 3698.1;Langerhans cells: 1990.8;Macrophages: 2837.1;monocytes: 3371.2;NK-cells: 1772.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6415.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "HMC-1: 678.1;THP-1: 390.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB009493: AB_638987, HPA041899: AB_10795266" "unprognostic (7.09e-2)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (4.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (8.04e-2)" "unprognostic (2.07e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.47e-2)" "unprognostic (1.72e-2)" "unprognostic (4.27e-2)" "unprognostic (4.39e-2)" 126.3 76.1 55.8 234.3 54.3 596.8 59.1 58.6 116.8 44.3 61.4 62.0 70.6 25.9 15.0 28.1 43.7 105.0 39.7 53.0 66.4 34.4 85.5 261.5 161.0 81.7 64.0 18.3 24.7 22.0 27.0 124.7 74.8 31.7 49.8 3.9 38.3 26.7 10.6 21.5 78.8 68.0 74.1 423.3 43.1 15.0 74.0 52.5 21.9 31.6 36.6 131.7 21.5 114.4 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 56.7 0.0 0.0 0.5 33.2 678.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 49.1 0.3 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.3 0.5 0.0 0.0 0.2 0.9 0.0 390.6 0.0 0.0 0.3 0.8 0.1 0.4 0.1 1.0 0.1 10.8 0.1 974.2 4983.5 2573.9 468.0 3367.8 246.5 22.4 9.5 64.2 1912.0 8.4 11.7 51.2 6415.4 1664.1 3413.8 1653.1 9.5 5260.2 55.8 54.3 58.6 116.8 53.0 66.4 81.7 64.0 74.8 74.1 74.0 114.4 24.5 57.7 168.4 0.0 50.9 55.2 2.0 0.0 1.2 0.1 11.5 43.3 6.8 34.3 43.4 20.2 0.0 19.8 987.6 1.7 1.9 2.1 3.9 1.3 1.4 47.1 0.0 87.8 0.1 5.8 28.0 24.9 5.6 1.5 753.7 0.3 73.2 25.0 3777.1 0.0 0.1 0.2 0.0 3698.1 1990.8 11.6 9.3 2837.1 56.9 18.7 3371.2 0.6 1772.4 0.0 0.1 1.3 2.3 1.2 19.4 1.5 0.5 8.9 20.5 1.8 78.9 5.3 10.0 0.9 3.0 4.9 44.6 38.9 236.5 0.1 0.5 1.8 UBE2A "HHR6A, HR6A, RAD6A, UBC2" ENSG00000077721 "Ubiquitin conjugating enzyme E2 A" P49459 X 119574536-119591083 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 508.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (2.27e-3)" "prognostic favorable (2.16e-4)" "unprognostic (1.12e-1)" "unprognostic (9.09e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.07e-4)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (6.54e-2)" "unprognostic (2.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.21e-1)" "unprognostic (7.92e-2)" 40.0 27.4 30.1 39.1 30.6 29.8 29.4 34.1 38.8 34.1 27.1 52.3 37.5 32.0 38.2 53.4 27.3 32.6 63.2 29.6 32.2 41.0 30.1 32.9 46.9 34.4 32.5 20.1 29.2 39.2 18.9 56.8 34.4 31.0 45.0 27.1 30.9 33.0 71.9 30.7 39.1 43.0 32.1 26.8 30.5 17.6 32.1 46.1 30.5 55.0 50.4 46.9 32.8 35.1 129.5 104.1 60.8 54.1 103.0 125.6 63.9 122.6 106.3 141.8 130.3 50.8 84.0 96.4 126.4 133.9 240.6 86.4 86.3 65.7 128.6 142.3 60.6 42.7 71.9 47.1 96.6 105.9 72.1 86.9 90.1 134.0 58.3 98.1 99.4 86.5 57.0 83.6 160.1 134.5 166.6 99.9 106.3 125.7 126.9 84.2 64.0 91.6 113.1 76.6 48.9 51.3 171.2 75.0 93.7 73.2 65.8 92.6 101.5 92.4 42.0 184.3 142.5 83.6 147.1 92.4 99.1 136.3 74.6 46.8 58.5 92.5 43.0 92.1 34.8 52.6 37.9 38.5 74.6 48.7 23.7 33.9 78.0 35.0 101.1 58.5 56.8 51.1 30.1 30.6 34.1 38.8 29.6 32.2 34.4 32.5 34.4 32.1 32.1 35.1 67.5 102.5 40.9 12.7 79.1 124.8 91.6 129.4 51.8 17.2 60.7 43.9 66.7 44.3 80.7 40.5 31.3 179.8 93.0 168.6 101.8 95.4 51.7 75.6 55.3 62.9 45.5 70.4 9.9 102.1 176.2 67.7 37.8 63.0 57.0 35.7 46.4 35.5 131.3 8.4 9.4 49.7 103.7 59.1 183.9 15.3 37.0 97.3 83.6 15.9 129.0 49.8 41.2 14.6 18.0 137.6 132.5 40.6 92.2 98.2 85.6 125.2 107.7 35.0 46.0 56.3 101.1 44.1 32.1 74.6 127.9 508.5 94.8 36.6 54.5 120.3 UBE2B "HHR6B, RAD6B, UBC2" ENSG00000119048 "Ubiquitin conjugating enzyme E2 B" P63146 5 134371469-134392108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 265.8" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 723.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 444.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 444.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (7.39e-2)" "unprognostic (6.66e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-1)" "unprognostic (2.49e-1)" "unprognostic (8.39e-2)" "unprognostic (1.64e-3)" "unprognostic (6.30e-3)" "unprognostic (3.42e-2)" "unprognostic (2.04e-1)" "unprognostic (5.52e-2)" 52.5 74.2 31.5 50.0 33.1 84.4 44.2 36.3 53.2 38.3 30.2 48.0 40.7 53.6 34.8 70.5 37.3 51.0 118.4 34.3 34.8 50.6 56.6 44.9 47.1 29.5 31.0 44.4 53.7 25.8 39.9 48.4 31.0 32.9 42.0 29.2 39.7 23.2 265.8 43.1 46.4 43.3 30.3 43.7 39.6 49.2 32.9 29.3 41.2 99.8 48.1 42.8 43.2 36.7 109.4 27.9 58.2 55.0 50.0 54.1 92.7 80.2 43.5 51.4 60.9 85.6 70.9 58.7 94.1 52.3 138.7 42.7 45.8 60.4 56.0 94.5 47.6 32.1 75.9 92.8 58.2 38.8 63.7 46.5 80.2 47.4 39.3 68.1 44.1 48.8 61.1 103.5 46.8 63.4 62.5 102.1 24.9 32.6 26.7 61.6 63.8 83.8 46.6 82.9 77.6 60.1 62.9 29.3 147.9 62.5 63.0 106.0 87.6 57.8 40.8 78.9 89.4 86.1 129.4 87.0 65.2 72.8 59.4 236.7 58.3 174.0 46.9 68.3 42.9 49.7 58.8 48.1 42.6 47.9 69.9 60.6 444.6 53.0 78.9 48.0 77.5 64.1 31.5 33.1 36.3 53.2 34.3 34.8 29.5 31.0 31.0 30.3 32.9 36.7 187.5 73.7 61.6 40.1 176.5 364.7 321.2 215.1 175.8 77.8 169.9 156.5 315.8 147.3 113.7 75.4 81.3 144.5 182.0 183.1 172.1 173.8 233.2 139.8 102.2 149.7 131.8 261.2 103.0 169.5 123.0 183.3 113.2 167.8 116.8 81.7 115.3 97.4 119.4 87.5 84.2 141.0 181.0 131.5 323.9 315.4 155.0 184.2 227.7 49.6 190.6 150.0 113.3 44.7 68.4 210.6 195.2 113.2 162.5 343.9 153.4 170.7 111.7 91.3 151.2 154.9 262.9 223.5 201.7 145.5 369.7 723.5 192.0 140.4 105.7 488.1 UBE2D3 UbcH5C ENSG00000109332 "Ubiquitin conjugating enzyme E2 D3" P61077 4 102794383-102868896 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (7.43e-2)" "unprognostic (3.19e-1)" "unprognostic (1.27e-2)" "unprognostic (5.78e-2)" "unprognostic (6.44e-2)" "unprognostic (4.96e-2)" "unprognostic (1.17e-1)" "unprognostic (8.44e-3)" "unprognostic (1.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.75e-2)" "unprognostic (3.31e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.08e-2)" "unprognostic (2.79e-1)" "unprognostic (4.54e-2)" "unprognostic (1.34e-2)" 182.7 171.7 85.7 172.0 92.6 478.3 141.9 101.1 120.6 127.1 93.4 154.9 154.0 125.3 113.8 173.4 125.9 142.5 149.4 92.1 103.9 172.2 251.4 175.3 189.6 102.5 96.0 131.5 154.2 133.5 98.4 159.0 99.8 106.8 144.4 129.0 116.7 102.1 243.6 136.4 158.3 129.9 101.4 149.5 144.4 127.0 95.6 198.5 159.2 197.9 197.0 185.6 128.0 113.7 301.6 169.1 275.4 223.4 286.2 408.0 235.9 301.2 395.1 260.1 243.6 257.4 416.4 319.3 190.6 304.4 336.8 168.6 294.7 400.8 352.5 299.6 149.8 292.0 165.8 209.6 300.3 415.5 240.4 314.0 247.9 288.6 398.9 334.3 343.4 258.7 372.9 316.4 350.9 243.1 613.4 235.1 200.2 341.0 167.1 318.4 269.9 231.5 261.5 283.7 275.6 232.1 183.5 464.8 349.6 318.2 193.0 241.0 318.4 270.0 231.1 179.2 276.3 277.9 389.8 491.3 288.2 227.2 297.0 614.9 253.7 394.0 163.5 256.0 216.3 165.9 203.4 194.4 217.6 139.2 205.8 190.5 817.2 215.7 271.9 149.8 229.6 422.1 85.7 92.6 101.1 120.6 92.1 103.9 102.5 96.0 99.8 101.4 95.6 113.7 303.4 166.7 193.1 98.9 291.7 844.0 693.9 408.2 233.9 133.7 251.5 166.9 229.8 193.0 242.3 139.8 125.1 311.5 317.4 336.1 547.8 361.0 779.4 257.1 246.7 344.0 240.8 348.7 159.7 382.2 561.6 286.0 202.3 371.3 224.9 154.8 193.1 235.7 392.9 122.8 145.8 283.8 303.2 403.0 825.6 635.1 164.7 415.1 357.5 111.5 399.4 160.0 280.2 104.5 185.0 454.4 347.2 149.0 296.4 612.3 335.8 428.8 242.4 170.6 105.2 270.6 531.9 217.2 180.7 258.2 813.3 638.4 382.5 172.3 268.2 784.3 ULBP1 RAET1I ENSG00000111981 "UL16 binding protein 1" Q9BZM6 6 149963943-149973715 "Predicted membrane proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 4.4;lung: 1.7;testis: 3.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 2.2;Breast myoepithelial cells: 3.0;Respiratory ciliated cells: 2.2;Squamous epithelial cells: 2.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebellum: 4.4;cerebral cortex: 1.9;hippocampal formation: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 16.5;HAP1: 29.3;HDLM-2: 17.1;HHSteC: 18.0;JURKAT: 26.1" "HPA007547, HPA071005" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA007547: AB_1079430, HPA071005: AB_2686332" "unprognostic (8.94e-3)" "unprognostic (2.44e-1)" "unprognostic (2.85e-2)" "unprognostic (2.33e-2)" "unprognostic (3.28e-4)" "unprognostic (6.69e-3)" "unprognostic (5.27e-2)" "unprognostic (2.47e-2)" "unprognostic (5.75e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-1)" "unprognostic (1.15e-2)" "unprognostic (5.57e-12)" "unprognostic (1.95e-1)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" "unprognostic (7.16e-2)" 0.2 0.1 0.1 0.2 0.1 0.3 0.0 4.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 1.6 0.2 0.4 0.1 1.7 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 3.3 0.1 0.1 0.4 0.1 0.1 0.0 0.0 0.2 2.1 1.0 1.6 0.0 3.3 6.8 3.2 3.0 0.9 0.6 2.0 0.2 3.1 3.5 0.7 16.5 6.9 0.7 29.3 1.4 2.7 17.1 3.8 0.3 0.6 0.0 18.0 0.1 1.2 9.1 6.8 13.6 2.5 0.0 1.1 26.1 3.3 0.0 3.5 2.7 4.3 0.0 0.5 1.4 2.3 0.0 1.3 0.5 0.0 0.4 1.0 0.4 4.4 2.0 0.0 1.3 2.9 6.4 0.3 1.6 0.0 1.4 0.0 0.5 0.7 2.3 8.7 5.0 3.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.1 4.4 1.9 1.6 0.2 0.1 0.2 0.5 0.1 0.1 0.2 1.6 6.4 2.2 0.0 0.5 0.1 0.5 0.0 0.6 0.0 1.0 3.0 0.9 0.0 0.6 0.0 0.0 0.0 0.3 0.4 0.0 0.3 0.1 0.2 0.6 1.1 0.0 0.0 0.1 0.6 0.0 1.6 0.0 0.7 0.0 0.1 0.7 0.0 0.1 0.0 0.0 0.5 0.0 0.3 0.3 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 2.2 0.0 0.0 1.6 1.3 0.2 0.2 2.5 0.6 0.0 0.7 0.2 0.3 0.1 ULBP2 RAET1H ENSG00000131015 "UL16 binding protein 2" Q9BZM5 6 149942014-149949235 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 6.1" "Cell type enhanced" "Detected in many" "Adipocytes: 28.9;Basal respiratory cells: 17.9;dendritic cells: 12.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 12.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.7" "Lineage enriched" "Detected in single" 6 "T-cells: 2.7" "Cell line enhanced" "Detected in many" "SiHa: 66.7;U-2197: 47.4" "CAB018974, HPA066741" Approved Supported "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 27: Brain & Skin - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "CAB018974: , HPA066741: " "unprognostic (2.09e-5)" "prognostic unfavorable (8.07e-4)" "unprognostic (2.38e-3)" "unprognostic (3.90e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.26e-2)" "unprognostic (2.38e-3)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (1.75e-2)" "unprognostic (1.42e-4)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (4.86e-1)" 1.5 0.7 1.3 0.6 1.6 1.8 0.7 1.6 2.6 0.9 0.7 0.2 0.2 0.1 0.1 6.1 0.2 0.5 2.0 3.0 1.0 2.1 0.5 3.4 0.3 1.8 1.2 0.0 0.4 0.6 0.5 1.6 1.8 0.2 0.1 0.2 0.7 0.1 0.3 0.5 0.2 0.7 0.8 0.2 0.3 1.5 1.1 0.7 1.2 0.7 0.8 1.4 1.6 1.7 19.9 1.8 0.5 6.1 1.1 5.6 3.3 20.1 11.8 20.6 16.8 7.4 11.0 0.0 29.9 23.0 29.6 13.9 7.6 18.4 11.8 9.1 3.9 1.1 2.8 0.0 7.1 0.0 1.5 2.7 13.9 18.3 8.0 16.7 11.9 16.6 2.5 0.0 15.4 13.9 1.8 0.0 0.0 3.6 10.2 3.0 4.5 0.0 29.0 5.7 0.6 0.0 66.7 1.4 1.9 3.2 1.8 8.5 18.8 13.5 17.1 47.4 23.5 0.0 0.1 0.9 19.2 10.7 9.9 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.8 1.5 0.0 0.0 0.3 1.8 0.0 0.4 0.0 0.0 1.7 0.5 1.3 1.6 1.6 2.6 3.0 1.0 1.8 1.2 1.8 0.8 1.1 1.7 28.9 0.0 1.3 0.0 1.2 3.7 6.5 17.9 7.4 0.0 1.3 4.4 0.3 0.0 9.4 1.8 0.0 0.0 12.1 0.5 0.0 7.5 7.0 0.3 0.5 9.1 0.0 0.0 3.0 8.8 0.5 3.0 1.1 0.2 0.0 0.1 7.1 0.2 2.2 0.0 0.7 0.3 2.0 0.8 2.1 8.0 0.0 3.1 1.8 0.0 0.0 0.4 4.1 0.5 0.3 4.5 0.0 0.0 1.4 1.4 0.0 0.1 1.4 0.0 0.0 1.0 4.2 3.1 7.0 11.8 2.8 0.0 11.0 0.6 0.4 5.2 USP14 TGT ENSG00000101557 "Ubiquitin specific peptidase 14" P54578 18 158383-214629 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001308 Approved Supported "Plasma membrane,Cytosol" NA NA 2700000 "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA001308: AB_1080499" "unprognostic (2.21e-1)" "unprognostic (4.05e-2)" "unprognostic (1.90e-1)" "unprognostic (2.59e-3)" "unprognostic (6.04e-2)" "prognostic unfavorable (7.81e-5)" "prognostic unfavorable (4.30e-5)" "unprognostic (5.14e-2)" "unprognostic (5.00e-2)" "prognostic favorable (7.91e-4)" "unprognostic (1.64e-2)" "unprognostic (2.39e-1)" "unprognostic (1.51e-3)" "unprognostic (2.58e-1)" "unprognostic (1.55e-1)" "unprognostic (2.20e-2)" "unprognostic (3.76e-2)" 26.0 21.5 19.9 22.7 21.3 23.9 17.0 20.1 22.9 15.5 13.9 17.8 13.9 17.0 23.8 24.0 14.6 14.6 24.8 21.0 24.5 23.4 25.3 15.1 21.6 25.4 21.7 13.3 13.0 21.2 14.3 26.5 25.7 29.7 19.3 15.5 15.2 19.6 55.6 15.4 12.4 24.7 20.3 13.8 15.1 17.9 26.0 21.8 20.4 36.4 31.3 22.6 15.3 23.3 91.6 75.4 62.7 64.5 60.7 60.0 109.6 115.5 64.9 118.9 110.5 98.9 48.7 133.1 86.6 99.1 114.4 50.9 125.1 91.7 134.9 38.7 59.0 72.5 46.0 78.1 60.5 184.1 70.8 48.4 69.1 122.3 69.5 55.0 93.5 65.9 106.2 99.3 119.1 76.2 105.2 52.4 59.4 56.0 83.5 87.8 78.6 98.0 88.7 79.9 71.8 60.1 120.7 59.2 52.5 68.0 58.2 51.5 103.9 138.7 104.3 128.8 170.6 62.3 125.7 130.9 80.0 77.3 88.4 10.7 18.1 13.8 27.9 25.8 33.6 21.1 27.5 29.5 25.6 16.4 26.7 26.2 1.5 39.3 20.5 18.7 28.6 19.4 19.9 21.3 20.1 22.9 21.0 24.5 25.4 21.7 25.7 20.3 26.0 23.3 40.0 22.4 40.4 27.7 52.7 58.6 53.3 42.0 51.8 58.0 33.4 23.5 44.9 31.5 48.3 44.1 31.3 92.3 58.1 22.5 45.0 60.6 70.9 44.9 56.3 43.1 22.1 102.0 58.8 54.0 71.8 49.0 43.8 80.8 34.8 47.1 28.2 45.4 50.9 116.1 54.4 22.5 46.8 31.5 53.4 21.6 31.7 45.5 35.6 33.7 48.8 39.4 46.4 35.2 74.8 75.8 16.9 45.9 72.7 71.4 15.2 56.0 40.2 50.3 0.0 49.6 51.4 34.1 68.1 57.9 52.4 135.6 55.0 58.9 33.5 51.8 UTRN "DMDL, DRP, DRP1" ENSG00000152818 Utrophin P46939 6 144285701-144853034 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 410.3;Early spermatids: 527.1;Late spermatids: 332.1;Microglial cells: 425.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HAP1: 219.4;HUVEC TERT2: 157.0;TIME: 203.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016348, HPA018894" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 4200 "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "CAB016348: AB_628424, HPA018894: AB_10600839" "unprognostic (3.47e-2)" "unprognostic (2.82e-1)" "unprognostic (2.32e-1)" "unprognostic (6.87e-3)" "unprognostic (1.75e-1)" "unprognostic (3.30e-2)" "unprognostic (3.99e-3)" "unprognostic (2.44e-1)" "unprognostic (9.24e-2)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.10e-2)" "prognostic favorable (7.61e-5)" "unprognostic (6.32e-2)" "unprognostic (2.20e-1)" "unprognostic (1.66e-1)" "unprognostic (1.49e-2)" 52.6 17.4 26.8 25.8 40.5 56.6 40.5 32.7 18.3 40.4 35.6 33.8 17.0 29.8 16.8 27.9 43.5 31.2 24.8 18.4 67.9 30.9 25.3 49.3 34.9 48.6 52.1 37.2 52.1 69.4 7.9 45.8 49.7 39.7 31.7 11.0 26.0 26.1 14.0 27.5 22.3 25.9 40.0 71.5 27.2 59.2 48.8 43.2 68.4 38.9 35.8 25.2 16.0 31.0 27.2 22.6 39.3 51.0 66.5 60.5 23.4 39.0 37.8 31.1 45.2 86.1 9.8 8.4 33.6 88.4 36.6 15.6 219.4 32.9 44.6 90.6 25.5 32.2 24.9 51.6 26.3 36.1 0.7 35.5 6.8 46.2 24.1 29.3 157.0 25.1 2.0 22.7 44.1 18.1 28.7 15.5 15.9 16.6 23.9 25.7 70.2 0.8 35.9 0.7 49.7 0.9 60.8 8.4 23.5 59.5 33.3 48.2 203.6 29.8 37.0 15.5 37.6 17.7 25.3 1.3 18.2 21.5 49.5 41.2 40.9 23.2 39.5 120.8 28.3 25.7 24.9 33.0 17.2 35.7 21.8 22.8 34.5 37.6 173.9 50.4 22.2 13.9 26.8 40.5 32.7 18.3 18.4 67.9 48.6 52.1 49.7 40.0 48.8 31.0 267.0 410.3 138.7 148.2 101.2 29.4 31.7 17.2 40.9 6.5 47.4 32.1 56.0 28.6 111.0 31.3 0.0 94.4 175.1 10.9 0.0 25.3 527.1 61.2 51.5 171.8 31.2 19.8 61.2 32.0 6.9 51.6 76.5 87.5 29.7 22.8 83.6 15.6 22.3 60.6 161.4 16.9 8.2 109.7 45.9 332.1 23.9 97.6 39.2 425.3 79.8 29.1 171.0 68.9 4.1 28.1 9.3 33.4 70.3 25.4 3.6 7.1 87.3 4.3 144.7 151.0 157.8 6.6 6.6 33.7 45.5 129.3 108.0 32.0 22.3 19.2 VASP ENSG00000125753 "Vasodilator stimulated phosphoprotein" P50552 19 45506579-45526983 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 443.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 52.7" "Group enriched" "Detected in all" 7 "granulocytes: 52.7;monocytes: 22.7" "Cell line enhanced" "Detected in all" "HMC-1: 270.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004612, HPA005724" Enhanced Supported "Plasma membrane,Cell Junctions,Focal adhesion sites" NA NA 32000000 "Cluster 52: Eosinophils - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cell Junctions, Focal adhesion sites" "CAB004612: AB_2213431, HPA005724: AB_1858721" "unprognostic (3.07e-2)" "unprognostic (1.07e-2)" "unprognostic (4.70e-2)" "unprognostic (7.85e-3)" "unprognostic (8.31e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.66e-3)" "unprognostic (1.58e-1)" "unprognostic (1.30e-2)" "unprognostic (3.64e-3)" "unprognostic (4.39e-1)" "prognostic unfavorable (5.91e-7)" "unprognostic (1.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.08e-2)" 54.5 24.6 9.3 75.2 8.3 94.0 42.5 9.2 12.6 37.7 11.0 88.9 61.9 89.1 6.0 37.5 54.4 27.0 36.4 8.1 9.4 39.1 27.3 58.2 48.7 13.0 10.9 22.5 20.6 10.7 17.1 31.5 13.8 43.8 20.4 1.9 30.7 39.1 12.5 32.8 63.6 36.5 11.7 107.0 70.5 14.7 15.0 24.9 27.6 8.5 32.0 71.6 39.0 12.0 68.9 66.3 20.6 35.6 10.2 17.4 50.5 70.2 52.8 47.4 40.9 30.1 142.0 31.2 55.7 56.4 31.3 60.6 6.2 69.5 15.9 87.0 14.8 183.7 32.3 55.4 56.6 68.1 270.1 26.8 38.2 44.5 28.5 38.3 71.1 25.8 112.1 67.5 29.4 53.7 30.3 58.7 36.0 65.1 44.5 21.6 12.6 12.2 40.9 216.2 23.0 16.3 83.6 41.7 48.2 13.0 45.7 115.2 107.0 74.7 74.4 24.7 112.4 32.8 43.3 54.7 52.4 82.3 92.3 13.3 8.5 52.7 4.1 13.9 2.8 3.4 3.3 3.9 5.5 3.3 2.1 2.5 34.5 4.0 22.7 2.1 2.6 5.8 9.3 8.3 9.2 12.6 8.1 9.4 13.0 10.9 13.8 11.7 15.0 12.0 80.9 16.0 19.5 2.9 99.4 98.3 95.6 48.8 37.0 6.9 53.5 57.0 19.0 48.6 41.5 33.1 27.1 67.1 85.9 202.3 17.6 138.6 3.2 33.9 30.5 77.0 114.7 20.0 2.6 98.2 443.6 26.7 81.6 58.1 83.1 17.4 48.5 15.8 160.1 6.7 3.4 159.3 44.7 132.5 232.0 3.8 26.1 192.9 49.8 10.3 162.9 13.2 185.3 2.0 2.3 212.5 245.5 49.2 38.2 73.4 134.6 20.4 18.6 14.7 131.5 46.5 89.4 18.9 15.5 38.7 77.7 140.9 95.7 21.0 129.5 144.8 VPS36 "C13orf9, CGI-145, Eap45" ENSG00000136100 "Vacuolar protein sorting 36 homolog" Q86VN1 13 52412602-52450634 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 265.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039734, HPA043947" Approved Supported "Vesicles,Lysosomes,Plasma membrane,Cell Junctions" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 43: THP-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Vesicles, Lysosomes" "Plasma membrane, Cell Junctions" "HPA039734: AB_2676652, HPA043947: AB_2678744" "unprognostic (2.43e-1)" "unprognostic (1.44e-1)" "unprognostic (2.80e-1)" "unprognostic (2.94e-1)" "unprognostic (1.56e-1)" "unprognostic (2.32e-1)" "unprognostic (6.57e-2)" "unprognostic (7.84e-2)" "unprognostic (3.96e-3)" "unprognostic (1.19e-2)" "unprognostic (9.37e-2)" "unprognostic (5.57e-2)" "prognostic favorable (9.91e-6)" "unprognostic (6.47e-3)" "unprognostic (1.83e-1)" "unprognostic (1.94e-1)" "unprognostic (9.83e-2)" 17.1 15.1 10.1 16.8 11.5 8.6 26.1 14.0 16.3 20.0 9.6 24.5 27.6 18.7 12.2 23.7 16.8 16.6 24.0 11.8 10.1 25.4 23.6 19.9 19.5 12.4 11.0 17.9 17.9 23.3 11.0 25.0 12.8 21.8 27.5 43.1 25.2 18.3 23.4 51.1 27.7 20.7 9.9 24.1 18.1 4.0 12.1 22.3 22.5 26.2 20.7 18.9 21.3 12.1 7.3 11.8 20.4 13.5 21.1 29.3 17.8 16.7 12.5 16.1 9.6 14.3 22.9 25.5 8.6 23.8 10.6 20.1 16.6 19.7 18.0 19.3 16.0 30.2 18.7 12.8 25.3 40.2 31.4 20.5 37.9 11.2 18.0 18.0 16.6 33.6 22.7 21.8 31.8 9.6 30.4 40.6 19.5 29.0 6.3 31.0 11.9 15.9 28.7 18.9 10.4 22.0 11.9 27.3 25.9 24.0 15.9 67.1 26.3 10.3 12.6 10.3 19.1 16.3 22.0 26.8 10.6 28.4 24.7 15.6 14.6 12.3 12.3 16.3 19.8 15.3 13.5 15.4 15.6 13.0 12.2 13.1 3.6 21.6 22.7 16.3 16.0 13.7 10.1 11.5 14.0 16.3 11.8 10.1 12.4 11.0 12.8 9.9 12.1 12.1 54.2 83.3 51.5 41.1 49.9 42.8 48.9 57.6 62.0 132.2 51.6 72.8 80.8 38.6 47.7 33.1 120.9 60.2 83.4 62.6 68.4 35.4 1.2 28.0 45.9 55.7 49.8 31.1 57.0 29.3 43.0 46.6 36.7 37.0 44.3 44.9 38.2 54.0 43.8 52.2 54.6 64.1 40.7 44.0 29.1 3.7 49.7 47.1 28.4 36.5 60.8 39.8 59.8 44.7 40.7 29.8 63.0 52.3 55.0 65.4 77.4 78.5 33.2 265.8 46.0 52.7 76.1 15.3 25.9 83.5 58.2 38.2 48.2 40.6 58.6 45.4 VTCN1 "B7-H4, B7H4, B7S1, B7x, FLJ22418" ENSG00000134258 "V-set domain containing T cell activation inhibitor 1" Q7Z7D3 1 117143587-117210960 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 100.9;fallopian tube: 32.7;pancreas: 30.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 62.3;Collecting duct cells: 55.2;Ductal cells: 83.6;Endometrial ciliated cells: 42.7;Exocrine glandular cells: 34.2;Glandular and luminal cells: 79.1" "Group enriched" "Detected in many" 6 "breast cancer: 55.8;endometrial cancer: 45.2;ovarian cancer: 49.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-BR-3: 244.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054200 Approved Approved "Plasma membrane,Cell Junctions,Focal adhesion sites" No NA "Cluster 5: Breast - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions, Focal adhesion sites" "HPA054200: AB_2682415" "unprognostic (4.13e-1)" "unprognostic (1.71e-3)" "unprognostic (2.95e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-3)" "unprognostic (2.56e-1)" "unprognostic (7.94e-2)" "unprognostic (4.86e-2)" "unprognostic (3.53e-1)" "unprognostic (1.17e-2)" "unprognostic (4.54e-2)" "unprognostic (5.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" "unprognostic (3.07e-1)" "unprognostic (1.45e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 100.9 0.0 0.0 15.3 0.0 0.0 0.4 4.5 5.0 0.4 32.7 5.0 0.2 0.0 0.0 17.3 1.1 0.7 0.0 0.0 0.0 0.1 30.1 0.0 0.1 0.8 0.0 3.0 0.0 0.0 22.1 7.8 0.2 2.8 0.0 0.1 0.0 0.0 3.6 1.1 0.1 0.1 0.0 0.0 0.0 3.2 0.1 0.0 1.0 0.1 1.7 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.9 0.0 7.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.9 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 4.2 0.1 1.2 0.0 0.0 244.8 0.1 29.9 14.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 2.5 6.9 0.0 0.0 62.3 18.4 1.1 0.0 22.6 55.2 0.0 3.4 1.1 0.0 0.0 83.6 2.5 42.7 4.4 0.6 0.0 0.0 0.8 34.2 1.4 0.4 0.0 79.1 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 6.1 0.0 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.3 11.3 0.0 0.0 0.0 1.6 0.0 0.3 8.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 3.0 0.5 0.0 0.0 4.8 WDR1 ENSG00000071127 "WD repeat domain 1" O75083 4 10074339-10116949 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1232.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020804, HPA036434, HPA070293" Approved Supported "Plasma membrane,Cell Junctions" NA NA 63000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cell Junctions" "CAB020804: , HPA036434: AB_2675121, HPA070293: AB_2732152" "unprognostic (1.35e-1)" "unprognostic (6.64e-2)" "unprognostic (5.31e-2)" "unprognostic (1.32e-3)" "unprognostic (2.65e-1)" "unprognostic (1.22e-1)" "unprognostic (2.63e-3)" "unprognostic (6.83e-3)" "unprognostic (1.69e-1)" "unprognostic (9.00e-3)" "unprognostic (2.52e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.73e-5)" "unprognostic (1.11e-1)" "unprognostic (3.56e-1)" "unprognostic (3.46e-2)" "unprognostic (4.83e-3)" 133.7 77.7 60.2 194.5 58.1 150.9 107.8 56.8 65.4 147.1 104.2 200.8 149.1 261.1 91.0 165.1 179.5 117.4 134.2 69.7 69.7 119.4 84.2 142.8 174.6 68.4 69.7 120.5 63.7 89.6 58.4 105.4 68.6 124.5 141.5 93.0 124.9 173.7 94.8 110.4 148.3 214.6 63.1 110.0 131.7 131.9 62.6 188.0 109.8 89.5 149.6 203.0 139.3 68.8 249.5 246.9 213.2 179.4 160.1 265.9 336.9 612.9 561.7 542.9 423.1 296.4 303.3 173.6 193.3 744.4 579.3 158.8 237.3 451.0 582.4 270.7 82.8 494.1 244.6 213.8 377.9 159.4 538.6 256.7 228.4 552.9 276.3 418.7 599.3 301.6 151.6 273.3 540.7 142.8 700.1 229.0 253.4 200.7 250.4 327.8 197.7 146.7 344.9 394.7 72.4 80.5 265.6 141.3 257.3 282.9 120.1 173.9 909.9 415.7 174.6 345.7 548.0 173.4 296.4 225.5 439.7 240.4 522.9 177.4 115.7 213.6 172.3 195.9 134.4 81.6 143.8 173.0 141.4 61.1 145.6 156.9 201.5 129.0 246.9 154.5 214.9 298.4 60.2 58.1 56.8 65.4 69.7 69.7 68.4 69.7 68.6 63.1 62.6 68.8 66.5 35.3 52.9 10.1 77.0 145.3 204.6 103.5 46.7 22.0 65.9 68.7 62.9 52.9 87.4 104.8 41.7 172.5 126.7 347.1 86.1 282.5 500.8 72.2 63.8 103.6 109.2 56.8 4.7 211.3 302.4 68.7 118.3 111.7 82.4 78.7 84.3 71.8 249.2 33.7 8.4 152.6 138.4 159.4 135.8 1232.1 46.9 174.9 80.0 15.0 303.7 82.6 147.2 11.6 9.6 322.8 244.4 92.2 78.3 150.7 169.0 113.1 73.5 28.0 98.6 46.1 168.1 81.6 64.3 74.9 137.0 231.6 132.2 77.2 172.8 193.6 XRN1 SEP1 ENSG00000114127 "5'-3' exoribonuclease 1" Q8IZH2 3 142306607-142448062 "Predicted intracellular proteins" "DNA-binding, Exonuclease, Hydrolase, Nuclease, RNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "RH-30: 119.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035005, HPA035006" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 59: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA035005: AB_10670695, HPA035006: AB_10672750" "unprognostic (3.52e-1)" "unprognostic (2.35e-2)" "unprognostic (2.49e-1)" "unprognostic (1.35e-2)" "unprognostic (2.40e-2)" "unprognostic (1.68e-2)" "unprognostic (1.24e-1)" "unprognostic (2.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (9.43e-4)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.43e-2)" "unprognostic (6.32e-2)" 9.0 6.8 2.9 12.2 4.5 21.2 10.7 11.4 5.5 8.4 6.4 8.2 11.0 9.8 7.8 7.0 6.2 8.0 5.5 3.2 4.0 6.8 16.2 8.6 13.1 3.8 3.2 10.1 8.1 8.8 6.0 10.5 4.2 8.8 9.4 14.6 7.4 6.1 11.7 9.4 12.4 6.6 4.5 12.8 9.0 9.3 3.9 14.4 8.7 9.7 11.3 7.7 8.2 6.8 22.1 3.9 9.6 8.6 11.1 17.0 5.9 9.9 12.9 12.3 15.2 3.6 6.1 8.9 10.3 13.3 10.0 8.6 8.6 5.2 19.2 21.4 6.5 12.7 7.3 3.5 9.6 12.8 12.7 14.0 6.1 8.8 11.7 12.1 11.4 9.7 8.0 20.4 11.7 4.5 11.2 7.6 3.0 3.4 4.4 9.0 119.2 11.4 6.5 10.8 5.7 7.3 17.3 10.4 8.2 5.9 11.9 10.8 16.0 9.0 4.7 10.3 8.7 29.1 14.2 13.7 8.4 7.2 7.9 31.0 5.8 17.2 10.0 5.4 7.1 9.8 7.7 9.1 2.9 7.2 10.1 7.0 21.2 5.9 5.0 8.0 6.2 3.1 2.9 4.5 11.4 5.5 3.2 4.0 3.8 3.2 4.2 4.5 3.9 6.8 66.1 54.5 33.3 74.7 55.9 25.6 33.7 22.7 33.6 33.7 27.2 21.0 26.5 18.6 30.2 46.0 50.1 22.9 80.8 46.5 11.7 16.5 49.9 31.9 50.7 40.6 28.2 43.6 101.6 12.5 7.8 41.8 48.4 29.0 21.5 33.7 33.9 48.0 16.3 26.9 114.2 22.5 14.2 28.9 23.0 19.1 24.8 38.8 14.2 81.5 41.4 21.0 50.4 126.7 120.4 18.6 41.9 29.0 111.7 44.0 43.4 13.2 34.2 53.9 6.6 56.0 39.9 61.8 20.5 27.6 28.3 53.5 69.8 37.1 15.0 43.8 YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 20.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 20.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB004370: AB_627370, HPA026480: AB_1858921" "unprognostic (3.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.87e-2)" "unprognostic (2.47e-2)" "unprognostic (6.24e-2)" "unprognostic (4.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.14e-1)" "unprognostic (8.12e-2)" "unprognostic (4.65e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (4.11e-1)" 25.2 13.5 11.9 10.5 12.7 4.1 21.8 12.7 14.3 17.4 11.5 21.8 24.8 16.0 17.9 22.7 13.9 18.9 13.1 11.7 13.7 27.9 50.6 17.2 6.2 13.9 13.2 12.4 26.5 20.0 6.1 41.7 13.5 15.0 22.7 8.3 21.0 11.9 8.3 16.7 23.7 15.9 14.2 27.4 21.3 19.0 14.3 10.5 22.0 14.6 8.8 20.3 11.5 14.1 42.7 20.8 64.3 50.6 37.8 46.5 75.6 27.9 56.2 32.0 43.7 49.9 30.7 0.1 28.8 47.3 41.0 24.3 60.8 49.1 62.3 0.2 20.7 12.6 19.4 35.1 30.6 9.9 21.7 35.7 51.7 48.5 53.6 39.8 109.8 7.0 56.1 18.4 46.1 29.3 6.0 13.0 40.9 26.0 26.4 7.4 50.6 3.6 46.8 49.6 13.1 15.3 57.5 42.9 37.1 42.3 29.7 20.5 95.6 78.4 86.2 59.9 75.8 15.7 8.3 2.6 29.7 13.8 47.6 20.2 0.0 1.0 2.2 0.0 1.5 0.1 0.4 1.2 0.0 0.0 1.0 1.7 0.0 1.1 0.0 0.0 0.1 0.6 11.9 12.7 12.7 14.3 11.7 13.7 13.9 13.2 13.5 14.2 14.3 14.1 120.3 25.6 36.8 18.9 3.3 60.2 46.8 21.4 50.1 6.0 38.1 26.7 18.2 24.3 31.3 29.5 6.2 37.1 52.9 40.3 3.9 29.6 29.4 32.8 35.0 91.0 22.8 12.0 0.4 39.2 26.6 35.4 57.6 43.6 13.9 35.9 39.7 44.9 4.9 3.3 10.3 37.2 14.2 5.4 14.7 11.7 18.3 5.0 24.9 46.9 2.0 16.8 16.5 31.7 30.2 51.0 28.8 12.8 28.9 65.4 33.1 45.6 29.0 8.6 19.7 35.9 23.8 20.3 13.6 53.1 49.7 45.6 27.5 42.4 36.7 66.6 YOD1 "DKFZp451J1719, DUBA8, OTUD2" ENSG00000180667 "YOD1 deubiquitinase" Q5VVQ6 1 207043849-207052980 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Unfolded protein response" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.6" "Cell type enhanced" "Detected in all" "Erythroid cells: 70.9;Glandular and luminal cells: 118.8;Late spermatids: 103.3;Urothelial cells: 86.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 86.3;K-562: 61.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028400, HPA028439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 110000 "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Plasma membrane, Cytosol" "HPA028400: AB_10599854, HPA028439: AB_10600994" "unprognostic (3.69e-2)" "unprognostic (8.72e-2)" "unprognostic (1.17e-1)" "unprognostic (2.39e-1)" "unprognostic (2.03e-2)" "unprognostic (3.28e-2)" "unprognostic (9.87e-3)" "unprognostic (9.38e-2)" "unprognostic (2.31e-3)" "unprognostic (8.96e-2)" "unprognostic (1.47e-3)" "unprognostic (1.03e-2)" "unprognostic (6.07e-2)" "unprognostic (6.86e-2)" "unprognostic (2.83e-1)" "unprognostic (1.79e-2)" "unprognostic (3.62e-1)" 3.0 4.5 3.5 4.3 3.8 58.6 5.4 3.7 5.5 5.2 3.9 3.9 4.2 3.7 2.9 24.6 2.6 2.8 4.4 4.0 3.4 4.7 5.4 8.5 4.7 5.5 3.6 2.9 3.2 1.6 2.7 5.7 4.4 3.0 3.9 7.6 6.6 2.7 4.8 15.6 4.8 2.5 3.6 5.7 8.8 3.8 5.0 9.9 5.3 4.1 7.6 4.6 10.9 9.9 11.8 6.1 9.5 5.7 3.3 4.4 18.5 7.6 5.9 5.7 5.7 11.7 11.9 6.1 3.0 4.7 2.7 12.6 0.1 9.3 6.4 4.9 10.3 86.3 27.6 5.6 3.1 11.5 29.2 3.1 7.1 4.6 17.7 6.7 5.0 12.5 61.1 0.0 5.0 0.1 10.1 6.3 9.1 4.9 13.5 5.1 0.4 4.5 5.7 13.0 5.0 11.0 12.5 14.4 16.7 8.4 5.1 8.1 2.4 4.8 12.6 4.0 10.0 9.5 0.6 9.0 5.7 0.0 3.3 1.0 0.3 0.5 0.2 0.3 0.3 0.0 0.3 0.2 0.3 0.1 0.3 0.4 0.7 0.3 0.2 0.1 0.2 0.2 3.5 3.8 3.7 5.5 4.0 3.4 5.5 3.6 4.4 3.6 5.0 9.9 6.8 41.7 12.2 20.5 3.3 31.6 29.4 8.1 21.1 8.0 6.2 3.8 7.0 2.8 10.0 1.8 4.2 2.7 8.2 39.4 1.9 4.1 35.4 50.5 19.0 6.7 8.9 70.9 8.5 10.5 3.2 5.5 36.2 118.8 8.2 6.1 2.9 8.6 2.8 11.8 6.4 5.0 12.2 10.0 12.5 103.3 1.5 8.3 14.2 6.5 5.2 4.9 6.2 6.0 16.4 24.4 67.8 2.2 4.8 38.2 7.8 7.0 21.6 17.9 6.6 3.6 6.0 10.9 4.6 33.9 40.2 1.8 6.9 9.0 7.5 86.5 ZDHHC20 "DHHC20, FLJ25952" ENSG00000180776 "Zinc finger DHHC-type palmitoyltransferase 20" Q5W0Z9 13 21372571-21459370 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 95.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 434.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014483, HPA014702" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "HPA014483: AB_1859000, HPA014702: AB_1859001" "unprognostic (1.31e-1)" "unprognostic (2.16e-3)" "unprognostic (7.31e-3)" "unprognostic (8.89e-2)" "unprognostic (3.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-1)" "unprognostic (1.24e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (6.55e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.76e-2)" "unprognostic (7.65e-2)" "unprognostic (6.15e-2)" "unprognostic (1.13e-2)" 10.9 9.2 15.2 17.6 52.9 30.0 11.5 51.8 23.3 16.2 0.0 16.9 19.3 13.8 9.6 30.2 10.9 17.1 7.9 12.0 27.0 6.7 9.8 17.0 18.0 70.8 40.7 9.7 9.0 8.9 4.4 18.8 60.3 15.1 16.1 5.6 8.5 12.2 4.0 22.1 19.0 15.2 35.1 16.1 39.5 31.7 40.7 22.6 16.4 9.4 19.5 22.9 9.3 95.0 32.9 16.4 27.7 18.1 24.5 26.7 68.3 35.6 36.3 23.3 20.6 33.8 102.5 34.8 19.3 44.7 23.8 52.7 30.5 26.5 44.8 40.0 20.4 61.8 11.7 19.6 14.1 43.3 25.8 24.2 19.4 23.6 16.2 30.0 37.6 45.9 17.3 14.9 35.3 27.2 62.0 17.2 22.9 87.3 18.0 49.8 49.1 12.7 28.9 59.7 25.2 11.4 46.0 28.7 19.3 28.6 27.0 21.8 62.6 25.0 24.0 41.7 27.4 15.6 19.9 37.7 18.2 23.6 73.1 12.6 16.2 3.8 10.1 14.9 9.3 4.6 8.7 8.7 8.4 3.4 8.1 8.4 3.0 11.2 13.8 4.1 10.4 13.5 15.2 52.9 51.8 23.3 12.0 27.0 70.8 40.7 60.3 35.1 40.7 95.0 27.6 51.3 31.5 29.0 19.9 1.0 7.8 1.4 18.2 7.4 21.9 13.7 7.4 14.3 20.7 11.0 8.4 20.7 34.7 35.5 0.0 8.5 91.3 23.4 25.2 25.7 24.0 8.4 69.1 12.2 20.9 13.6 53.0 34.5 14.0 16.1 20.0 20.8 21.7 18.5 80.0 29.1 2.0 92.5 3.2 81.2 15.5 49.0 1.8 46.9 48.4 3.7 30.9 54.8 434.3 22.8 25.5 10.9 18.1 14.5 30.3 6.3 11.7 9.5 19.7 12.7 11.6 10.4 14.1 28.1 1.6 44.6 28.4 9.7 25.1 25.6 ZNF185 SCELL ENSG00000147394 "Zinc finger protein 185 with LIM domain" O15231 X 152914442-152973480 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 328.7;esophagus: 326.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 32.2;Pancreatic endocrine cells: 72.0;Squamous epithelial cells: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.8" "Group enriched" "Detected in many" 5 "granulocytes: 51.8;monocytes: 27.4" "Cell line enhanced" "Detected in many" "A-431: 124.4;EFO-21: 139.9;HBEC3-KT: 100.0;PC-3: 87.7;TIME: 236.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000400, HPA016438" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 220000 "Cluster 18: Basophils - Vesicular transport" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Actin filaments, Focal adhesion sites" "HPA000400: AB_1080685, HPA016438: AB_1859109" "unprognostic (1.34e-1)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (2.43e-2)" "unprognostic (9.75e-3)" "unprognostic (2.69e-1)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (7.94e-2)" "unprognostic (6.28e-2)" "prognostic unfavorable (3.30e-5)" "unprognostic (5.18e-2)" "unprognostic (8.12e-2)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" 5.2 11.6 4.0 5.6 4.2 8.7 12.2 4.8 3.7 69.5 10.9 4.5 1.8 21.8 328.7 326.7 16.4 6.7 1.8 3.2 3.9 11.0 2.1 12.1 4.5 3.5 3.8 6.1 4.3 3.7 8.4 24.9 3.5 24.5 4.2 3.4 44.8 144.1 2.9 53.7 2.6 10.3 4.2 4.5 7.4 3.4 4.3 3.6 21.3 2.9 41.0 11.6 117.5 3.9 124.4 25.9 2.4 1.6 3.0 4.0 5.5 6.0 0.4 14.8 2.2 0.9 36.7 1.6 139.9 9.0 1.4 17.3 3.7 100.0 60.1 1.5 2.4 7.9 9.8 4.1 7.0 0.5 0.6 2.9 70.2 1.6 57.0 14.6 76.5 1.6 0.5 1.1 0.4 29.1 0.5 0.7 1.9 31.4 87.7 0.5 0.4 0.9 7.7 11.5 1.0 8.2 0.2 22.7 3.6 23.3 23.3 2.7 236.2 0.8 50.5 3.0 4.5 1.2 1.0 1.1 1.6 8.9 1.7 51.8 27.4 11.4 1.0 24.4 0.6 0.7 0.7 1.2 7.4 0.6 1.1 0.7 18.5 0.5 21.1 4.9 1.0 20.7 4.0 4.2 4.8 3.7 3.2 3.9 3.5 3.8 3.5 4.2 4.3 3.9 1.1 12.8 2.6 1.3 0.7 9.2 6.2 5.7 4.6 0.5 5.7 7.6 0.9 1.5 9.4 9.2 2.1 3.8 1.7 1.0 0.0 8.6 0.6 14.1 4.2 1.1 0.0 0.0 1.0 3.0 5.0 2.2 2.6 32.2 1.3 3.9 1.4 0.1 9.4 0.0 1.7 2.5 2.0 11.3 4.0 0.3 1.2 9.5 3.6 0.0 14.4 4.0 0.0 1.0 1.4 72.0 0.3 1.2 0.1 7.6 0.3 1.2 6.9 0.3 0.0 0.5 1.9 4.2 5.8 69.7 21.2 0.7 0.8 0.4 2.4 21.3 ZNF655 "VIK, VIK-1" ENSG00000197343 "Zinc finger protein 655" Q8N720 7 99558406-99576453 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029534, HPA050750" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane" "HPA029534: AB_10603008, HPA050750: AB_2681225" "prognostic favorable (7.12e-4)" "unprognostic (3.03e-2)" "unprognostic (9.62e-2)" "unprognostic (5.00e-1)" "unprognostic (1.51e-1)" "unprognostic (5.42e-2)" "unprognostic (3.31e-2)" "unprognostic (3.93e-3)" "prognostic unfavorable (7.24e-4)" "unprognostic (2.01e-1)" "unprognostic (1.49e-2)" "unprognostic (1.18e-1)" "unprognostic (1.42e-2)" "unprognostic (2.16e-1)" "unprognostic (2.11e-1)" "unprognostic (1.62e-2)" "unprognostic (1.12e-1)" 11.6 11.9 7.0 14.3 6.2 8.9 12.8 8.3 7.8 13.2 5.9 15.5 15.9 10.1 11.0 26.9 11.5 10.2 8.4 6.3 6.1 13.8 14.9 15.3 19.7 5.0 5.5 13.9 21.1 14.4 8.2 12.5 6.4 11.4 11.8 8.5 16.7 11.3 12.7 18.4 13.8 11.7 5.1 14.2 18.0 7.4 6.3 22.6 11.8 13.5 17.3 18.8 14.9 9.6 40.5 35.9 16.5 23.9 15.8 25.4 12.4 24.0 45.8 40.7 37.8 20.1 37.0 31.8 0.4 33.2 52.0 25.2 18.0 29.6 40.6 34.5 23.6 18.9 16.0 27.8 24.1 38.1 35.9 21.1 32.8 35.8 50.6 21.4 17.3 26.4 54.4 39.7 24.4 0.1 53.9 36.6 21.1 0.1 0.0 19.9 14.0 52.9 25.9 42.8 17.4 37.6 25.1 0.7 27.2 24.0 12.2 20.2 13.3 24.3 60.2 43.4 43.6 47.3 72.7 63.4 23.5 18.2 39.9 147.8 43.2 74.4 47.8 47.2 45.1 32.7 44.1 55.7 40.3 31.3 35.0 43.8 50.3 37.0 55.2 23.3 61.3 55.4 7.0 6.2 8.3 7.8 6.3 6.1 5.0 5.5 6.4 5.1 6.3 9.6 19.5 96.1 82.8 51.2 53.2 44.7 46.5 36.5 42.1 48.8 34.4 25.1 36.1 31.5 44.3 23.9 41.7 31.6 76.3 46.3 33.2 31.6 12.8 25.8 33.9 20.4 41.5 12.8 53.4 36.2 42.7 32.7 37.2 33.0 18.9 70.8 19.2 24.6 37.4 50.5 57.4 40.4 18.3 63.4 31.6 9.7 25.4 56.0 23.2 44.0 59.2 24.9 106.1 61.3 75.3 48.2 55.2 25.2 55.4 44.5 48.1 41.1 26.0 45.8 13.1 39.9 31.7 39.0 29.8 55.6 48.9 73.6 62.5 30.0 28.1 64.0