Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AACS "ACSF1, FLJ12389, SUR-5" ENSG00000081760 "Acetoacetyl-CoA synthetase" Q86V21 12 125065434-125143333 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 67.1;Excitatory neurons: 59.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058815 Approved Approved Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA058815: AB_2683826" "unprognostic (1.28e-1)" "unprognostic (9.78e-2)" "unprognostic (1.86e-1)" "unprognostic (1.06e-1)" "unprognostic (1.98e-3)" "unprognostic (9.46e-3)" "unprognostic (6.60e-6)" "unprognostic (3.03e-2)" "unprognostic (3.32e-2)" "unprognostic (2.45e-2)" "unprognostic (2.38e-2)" "unprognostic (3.04e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-1)" "unprognostic (3.73e-2)" "unprognostic (7.71e-2)" "unprognostic (6.80e-2)" 31.7 7.8 6.4 5.6 8.2 3.7 43.4 2.8 11.0 14.6 3.2 12.7 17.9 6.3 8.7 30.9 8.5 7.6 7.4 9.1 3.7 10.3 3.9 6.2 5.8 6.1 3.1 6.0 12.8 9.6 8.5 6.1 6.0 8.6 11.3 6.2 48.2 7.5 5.5 40.4 10.4 5.8 2.4 5.2 16.9 13.5 5.0 10.4 10.0 7.6 10.2 6.1 14.3 6.5 26.8 26.2 11.2 15.3 40.3 26.1 18.7 21.2 20.1 24.6 21.8 34.0 17.4 16.5 21.3 25.7 10.6 28.4 21.0 22.8 13.2 17.8 19.2 13.1 16.9 26.2 33.5 9.4 12.8 29.1 18.2 21.0 21.0 30.8 18.1 9.5 9.4 9.9 15.9 49.1 10.8 12.7 14.2 28.0 30.4 2.1 28.2 23.0 25.0 40.2 29.7 8.6 22.4 35.0 16.6 10.8 26.2 20.7 17.4 11.8 18.7 13.4 16.4 22.0 13.6 18.0 14.8 15.4 13.2 7.7 2.1 5.9 3.3 0.6 4.4 2.4 3.1 2.5 2.4 1.2 4.4 3.0 0.3 5.4 0.7 9.9 2.1 3.4 6.4 8.2 2.8 11.0 9.1 3.7 6.1 3.1 6.0 2.4 5.0 6.5 4.2 6.4 17.3 16.3 4.5 16.6 5.6 14.1 9.1 20.9 23.6 16.9 9.4 17.2 12.0 5.5 27.1 2.1 6.5 14.0 7.9 11.0 67.1 6.3 15.3 6.5 25.2 0.8 59.4 10.7 8.7 11.8 13.3 12.3 2.5 13.1 2.2 4.2 4.8 6.7 28.6 22.0 16.2 4.1 9.0 22.5 9.3 3.9 5.4 5.6 5.4 5.6 5.2 12.1 12.5 9.9 7.4 5.3 12.1 8.2 10.7 6.5 5.7 21.8 0.0 8.6 7.7 22.0 5.3 25.3 28.1 2.5 8.1 20.8 15.8 5.6 ABCA2 ABC2 ENSG00000107331 "ATP binding cassette subfamily A member 2" Q9BZC7 9 137007234-137028922 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "brain: 543.0" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 388.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 66.4" "Low region specificity" "Detected in all" HPA042886 Approved Supported Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA042886: AB_2678213" "unprognostic (1.01e-2)" "unprognostic (9.21e-3)" "unprognostic (9.59e-2)" "unprognostic (6.15e-2)" "unprognostic (1.02e-1)" "unprognostic (8.08e-2)" "unprognostic (2.20e-2)" "unprognostic (1.13e-2)" "unprognostic (5.61e-3)" "unprognostic (1.76e-1)" "unprognostic (2.93e-2)" "unprognostic (2.74e-2)" "unprognostic (6.78e-3)" "unprognostic (3.14e-3)" "unprognostic (1.37e-1)" "unprognostic (2.80e-1)" "unprognostic (1.36e-1)" 9.0 6.0 90.2 4.2 269.7 6.7 6.3 194.3 189.0 5.9 0.0 7.9 3.0 4.3 4.5 3.3 6.2 5.9 9.1 92.4 101.3 7.1 7.4 6.2 4.6 284.9 211.4 3.2 9.3 13.4 23.4 3.1 255.1 7.1 2.2 2.7 8.4 4.7 7.3 6.6 6.5 2.4 135.7 9.5 11.6 2.9 204.9 2.9 15.2 3.5 1.8 5.6 5.3 543.0 8.6 9.2 4.5 18.2 11.1 11.8 7.9 9.5 3.8 4.2 1.5 2.8 10.3 0.4 26.2 10.2 4.1 14.4 2.9 6.9 0.8 6.4 5.9 0.8 26.2 3.5 5.5 13.3 14.5 5.0 6.3 3.0 0.9 15.3 2.4 2.7 2.2 1.5 5.3 25.7 0.1 29.1 2.4 10.9 9.5 13.3 4.6 13.0 2.9 2.0 17.4 20.0 10.1 19.6 7.2 0.3 66.4 17.4 11.9 11.2 6.1 16.0 3.9 0.3 0.2 0.1 19.0 2.6 5.8 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.6 0.2 0.3 90.2 269.7 194.3 189.0 92.4 101.3 284.9 211.4 255.1 135.7 204.9 543.0 7.2 0.0 0.0 26.1 2.3 3.3 1.5 7.1 3.4 12.6 6.2 9.1 5.1 17.2 2.3 1.8 14.6 1.0 24.0 15.2 1.9 2.9 1.0 6.7 4.8 4.7 34.7 6.6 23.4 1.5 1.2 6.4 5.1 6.9 0.0 12.6 6.1 8.6 1.2 37.0 20.8 7.0 2.0 3.5 4.6 1.6 22.1 2.7 5.4 4.7 0.9 12.8 24.7 12.5 388.7 2.3 7.1 23.7 6.7 2.4 11.6 1.4 4.9 7.9 0.0 11.4 4.7 0.5 4.7 1.7 2.7 0.8 13.2 2.8 11.0 1.3 ABCB9 EST122234 ENSG00000150967 "ATP binding cassette subfamily B member 9" Q9NP78 12 122920951-122981649 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peptide transport, Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.4;testis: 17.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 46.3;Inhibitory neurons: 41.7;Plasma cells: 92.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6;memory B-cell: 2.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "GAMG: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033052, HPA035113, HPA035114" Approved Supported Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB033052: AB_2273463, HPA035113: AB_2674470, HPA035114: AB_10601329" "unprognostic (1.47e-2)" "unprognostic (6.46e-4)" "unprognostic (3.96e-2)" "unprognostic (2.73e-1)" "prognostic unfavorable (5.65e-4)" "unprognostic (1.46e-1)" "unprognostic (2.67e-2)" "unprognostic (2.35e-1)" "unprognostic (4.08e-2)" "unprognostic (6.07e-2)" "unprognostic (2.28e-1)" "unprognostic (1.24e-1)" "unprognostic (1.37e-2)" "unprognostic (6.97e-2)" "unprognostic (1.70e-1)" "unprognostic (3.58e-3)" "unprognostic (2.71e-2)" 3.0 3.1 11.9 1.6 10.4 3.4 3.9 19.7 20.4 3.1 0.0 2.4 2.7 3.0 4.9 2.9 2.9 2.5 4.9 8.2 7.5 3.6 1.2 1.6 1.6 7.3 9.1 4.0 3.2 2.8 11.6 1.8 6.0 3.5 2.1 7.3 5.6 2.8 1.6 3.3 3.4 2.0 2.1 3.6 3.4 17.8 16.0 1.3 3.0 1.2 1.9 1.9 3.1 10.6 4.7 8.6 4.7 4.5 2.0 3.8 2.2 3.0 4.3 5.1 3.2 3.7 5.3 5.2 3.4 2.8 25.9 4.3 3.5 7.2 2.0 1.0 7.0 22.9 7.7 5.9 2.2 1.1 9.0 5.3 2.8 7.5 2.3 12.5 5.7 5.1 4.6 3.8 2.9 10.6 1.7 2.2 1.5 5.0 8.4 6.4 1.3 5.0 2.6 3.1 5.0 1.5 1.5 10.7 10.7 1.8 12.6 1.6 2.5 3.6 12.2 11.5 8.8 12.3 7.4 1.5 6.3 2.5 20.2 2.6 0.3 0.3 0.3 0.1 0.8 2.5 0.3 0.3 0.2 0.5 0.6 0.6 0.7 0.2 0.1 0.1 0.2 0.8 11.9 10.4 19.7 20.4 8.2 7.5 7.3 9.1 6.0 2.1 16.0 10.6 9.7 6.4 4.6 13.4 15.9 3.2 2.8 1.5 8.6 10.7 3.9 5.0 2.0 0.0 2.5 3.7 14.6 5.2 3.4 1.9 0.0 3.8 8.9 2.6 2.6 4.0 1.2 2.1 46.3 1.5 1.8 2.0 4.1 5.6 2.5 3.0 2.9 1.2 1.1 6.7 41.7 1.1 0.0 1.0 2.1 23.2 2.8 1.8 5.4 7.5 0.3 20.0 2.1 4.0 18.1 2.5 0.1 2.6 92.2 2.1 4.1 0.9 0.7 5.3 6.6 2.1 3.7 9.6 3.5 3.3 3.1 1.4 3.9 2.9 2.6 1.8 ABCG8 GBD4 ENSG00000143921 "ATP binding cassette subfamily G member 8" Q9H221 2 43831942-43882988 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 40 "intestine: 31.5;liver: 63.4" "Group enriched" "Detected in some" 4 "Hepatocytes: 32.0;Proximal enterocytes: 13.8" "Cancer enriched" "Detected in some" 30 "liver cancer: 21.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 44 "Hep G2: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA019556 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA019556: AB_1844444" "unprognostic (1.99e-1)" "unprognostic (4.49e-1)" "unprognostic (3.22e-1)" "unprognostic (1.37e-1)" "unprognostic (3.09e-2)" "unprognostic (2.43e-1)" "unprognostic (1.99e-3)" "unprognostic (1.27e-1)" "unprognostic (6.28e-1)" "unprognostic (6.14e-3)" "unprognostic (4.69e-1)" "unprognostic (1.76e-1)" "unprognostic (2.68e-1)" "unprognostic (7.86e-3)" "unprognostic (5.03e-1)" "unprognostic (1.50e-1)" 0.1 0.0 0.4 0.1 0.3 0.1 0.0 0.2 1.1 0.0 0.0 0.2 29.8 0.1 0.0 0.0 0.2 0.9 0.0 0.2 0.4 0.3 63.4 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.1 31.5 0.0 0.0 0.1 0.3 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.1 0.2 0.4 0.3 0.1 0.4 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 2.8 0.6 1.8 0.0 0.0 0.1 0.0 1.9 0.1 0.0 0.2 0.7 0.6 0.0 2.7 3.6 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.4 32.0 0.0 0.0 2.8 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 5.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.2 0.0 ABHD14A "DKFZP564O243, DORZ1" ENSG00000248487 "Abhydrolase domain containing 14A" Q9BUJ0 3 51971426-51981199 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 124.3;Rod photoreceptor cells: 115.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 79.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038153, HPA056913" Approved Enhanced Vesicles NA NA 420000 "Cluster 20: T-cells - T-cell receptor" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA038153: AB_2675868, HPA056913: AB_2683275" "unprognostic (4.15e-3)" "unprognostic (6.73e-2)" "unprognostic (1.98e-1)" "unprognostic (3.34e-2)" "unprognostic (2.71e-1)" "unprognostic (1.08e-2)" "unprognostic (8.92e-2)" "prognostic favorable (4.72e-4)" "unprognostic (3.96e-1)" "unprognostic (2.46e-2)" "unprognostic (5.52e-3)" "unprognostic (1.51e-2)" "unprognostic (1.97e-2)" "unprognostic (9.74e-2)" "unprognostic (2.17e-1)" "unprognostic (1.33e-1)" "unprognostic (1.30e-2)" 23.5 48.6 65.2 8.3 64.5 13.5 18.4 72.3 78.0 25.1 67.6 18.1 10.6 15.0 28.3 8.4 24.2 12.1 36.1 64.8 69.3 35.3 26.1 14.3 11.4 59.6 60.0 27.1 26.6 27.1 49.6 8.9 59.7 19.0 6.9 43.5 23.2 14.5 34.8 7.6 12.9 7.5 59.2 14.6 17.7 13.2 69.4 11.5 32.8 39.1 8.4 19.4 16.7 59.8 6.9 12.9 8.2 24.7 79.8 39.9 4.5 9.0 14.8 10.6 14.3 14.8 27.0 7.8 6.0 22.4 12.1 6.2 9.0 10.0 3.4 25.1 10.0 22.7 37.4 50.0 22.4 31.4 29.0 37.9 6.6 9.0 4.6 23.7 13.8 14.6 9.3 25.4 16.8 7.8 14.5 31.8 4.7 32.4 30.4 10.3 4.2 73.9 20.7 10.6 16.8 26.1 22.5 4.7 13.5 1.7 7.1 33.7 8.2 9.6 10.4 23.4 10.7 37.0 37.4 6.6 18.1 49.6 14.1 6.9 20.3 15.2 94.0 12.7 96.5 49.0 80.9 83.5 36.2 41.5 73.7 79.0 2.1 45.5 8.6 46.0 88.4 54.9 65.2 64.5 72.3 78.0 64.8 69.3 59.6 60.0 59.7 59.2 69.4 59.8 15.9 6.4 21.7 0.0 20.2 9.7 25.1 29.0 4.0 90.8 21.0 22.9 24.3 20.0 20.8 33.1 25.0 10.3 29.6 7.1 33.2 15.5 4.7 23.5 18.0 14.1 40.2 2.5 0.0 12.4 15.3 36.9 4.6 14.9 15.2 12.8 17.2 16.2 29.3 58.9 0.0 14.0 24.4 14.2 18.5 24.9 88.0 14.6 12.4 0.0 7.4 59.9 41.2 0.0 0.0 17.1 5.6 33.1 16.3 17.0 13.8 124.3 29.5 115.2 19.7 24.7 16.8 18.2 57.8 1.8 5.5 4.9 28.9 20.6 15.3 19.5 ABHD14A-ACY1 ENSG00000114786 "ABHD14A-ACY1 readthrough" 3 51974706-51989183 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 4.8;Collecting duct cells: 5.5;Distal tubular cells: 3.9;Proximal tubular cells: 16.8;Theca cells: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA036174, HPA036175, HPA038153" Approved Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA036174: AB_2674988, HPA036175: AB_2674989, HPA038153: AB_2675868" "unprognostic (8.40e-2)" "unprognostic (1.37e-1)" "unprognostic (4.90e-2)" "unprognostic (7.22e-3)" "unprognostic (3.83e-2)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.35e-1)" "unprognostic (6.23e-2)" "unprognostic (2.71e-1)" "unprognostic (1.10e-1)" "unprognostic (1.29e-2)" "unprognostic (9.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (7.11e-4)" 0.5 0.8 0.1 0.1 0.1 0.0 0.4 0.6 0.4 0.2 0.2 0.2 0.0 0.6 0.0 0.2 0.5 0.1 0.2 0.1 0.2 0.3 0.3 0.2 0.0 0.2 0.1 0.1 0.3 0.0 0.4 0.0 0.2 0.2 0.0 0.0 0.4 0.0 0.7 0.2 0.2 0.0 0.2 0.2 0.4 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.1 0.0 0.5 0.2 0.0 0.0 0.4 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.2 0.3 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.4 0.5 1.2 0.9 0.8 0.6 0.7 1.1 1.0 0.5 0.7 1.0 0.0 1.1 0.6 0.6 1.0 0.5 0.1 0.1 0.6 0.4 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.2 1.4 0.0 4.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 3.2 3.2 0.0 0.0 1.8 5.5 0.0 0.0 0.9 0.1 3.9 1.5 0.0 0.4 1.4 0.6 0.0 0.8 1.0 1.2 0.0 1.0 2.0 0.8 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.5 1.2 2.0 0.0 0.0 0.0 0.0 0.2 16.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 6.3 0.0 0.0 ABT1 Esf2 ENSG00000146109 "Activator of basal transcription 1" Q9ULW3 6 26596953-26600739 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077039 Approved Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA077039: AB_2732328" "unprognostic (1.32e-1)" "unprognostic (3.94e-2)" "unprognostic (3.05e-1)" "unprognostic (1.15e-3)" "unprognostic (1.77e-1)" "unprognostic (7.74e-2)" "unprognostic (2.55e-2)" "unprognostic (2.36e-2)" "unprognostic (1.85e-2)" "prognostic favorable (1.89e-4)" "unprognostic (2.30e-3)" "unprognostic (2.93e-2)" "unprognostic (7.25e-3)" "unprognostic (7.20e-2)" "unprognostic (9.57e-2)" "unprognostic (1.49e-1)" "prognostic favorable (3.80e-4)" 9.3 8.0 6.5 9.5 6.7 23.2 9.3 7.8 7.7 8.9 6.5 10.1 10.0 10.8 6.3 13.9 9.2 5.9 8.7 6.5 6.4 8.2 13.0 7.9 15.8 6.4 6.4 9.2 9.4 8.3 7.3 10.7 6.4 8.2 6.7 4.7 9.0 6.7 9.6 14.3 11.6 5.7 6.4 14.8 9.9 8.0 6.6 13.0 7.3 7.1 10.5 9.3 9.7 6.8 23.3 11.9 16.3 28.4 8.9 9.3 23.9 13.4 13.6 20.0 19.5 21.6 10.0 33.8 30.0 11.1 15.9 14.5 19.0 19.5 11.7 18.9 38.7 22.2 11.2 40.6 14.3 30.6 21.7 12.4 17.9 15.9 9.4 9.3 17.5 26.2 39.3 22.1 11.2 23.6 35.6 39.1 16.8 14.9 15.9 21.4 13.2 35.8 12.5 18.7 21.4 17.2 8.3 21.6 32.9 8.6 20.8 24.6 15.1 15.2 11.2 12.2 27.3 25.8 40.9 30.9 7.2 37.6 23.8 76.1 41.6 53.8 66.1 40.2 63.3 66.5 63.8 66.2 39.7 70.2 67.4 60.8 37.2 57.5 41.7 37.1 76.3 88.1 6.5 6.7 7.8 7.7 6.5 6.4 6.4 6.4 6.4 6.4 6.6 6.8 22.4 16.0 15.5 3.3 41.8 59.9 35.8 65.2 34.1 16.2 23.1 22.2 7.1 21.5 31.8 11.0 2.1 96.0 50.8 16.1 41.1 39.4 39.7 12.1 14.0 31.6 34.0 26.9 4.4 38.7 97.5 21.1 16.8 17.3 29.1 17.7 25.4 21.2 42.2 15.2 4.3 25.3 50.8 21.2 22.6 81.8 27.7 22.2 16.0 2.8 32.3 22.0 78.2 3.5 4.5 35.9 19.5 23.7 29.4 31.6 27.9 24.4 21.8 17.2 19.7 15.1 23.4 29.6 41.2 28.3 59.8 109.5 44.3 24.5 29.5 33.6 AC000120.3 ENSG00000285953 "Novel protein" 7 92131774-92245924 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 1.1;granulocytes: 1.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" HPA049606 Uncertain Approved Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 1: K-562 - Erythropoiesis" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049606: AB_2680832" 2.1 1.0 0.5 1.1 1.0 0.4 2.0 1.8 0.9 3.6 0.0 1.0 0.4 1.8 0.0 1.2 2.1 1.6 1.4 0.1 0.9 2.5 2.1 2.1 1.7 0.8 0.7 2.6 1.4 3.2 2.9 0.8 1.5 1.3 2.2 0.9 2.0 3.2 0.2 1.1 1.7 0.5 0.7 0.4 5.9 0.5 1.8 2.5 3.7 2.5 1.2 2.0 3.2 2.7 4.2 2.8 4.3 9.2 4.3 5.2 4.9 7.8 7.8 2.2 4.4 5.7 3.2 4.1 4.4 2.6 6.4 5.0 10.9 3.9 3.1 4.9 4.3 1.3 4.2 6.9 2.9 2.1 3.9 5.7 6.7 2.8 5.4 3.3 12.8 3.7 6.0 1.8 4.4 1.1 3.6 4.3 5.0 2.5 7.0 4.8 1.9 2.3 3.3 2.3 8.0 3.0 3.1 8.4 2.9 2.4 2.0 2.6 3.0 7.1 2.5 2.1 3.9 7.6 2.9 3.0 4.6 0.0 0.1 0.2 0.1 0.1 0.5 0.5 0.2 0.2 0.4 0.2 0.3 0.3 0.0 0.3 0.1 0.2 0.2 0.3 0.5 1.0 1.8 0.9 0.1 0.9 0.8 0.7 0.8 0.5 0.5 2.0 0.0 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC092718.2 ENSG00000260643 "Novel protein" 16 81053587-81096296 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 13.4" HPA041368 Approved Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 14: REH - Unknown function" Vesicles "HPA041368: AB_10804001" "unprognostic (3.87e-2)" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (2.12e-2)" "unprognostic (8.06e-2)" "unprognostic (1.08e-1)" "unprognostic (3.95e-2)" "unprognostic (8.11e-2)" "unprognostic (2.85e-1)" "unprognostic (2.42e-1)" "unprognostic (3.94e-2)" "unprognostic (3.19e-1)" "unprognostic (2.69e-2)" "unprognostic (2.11e-1)" "unprognostic (1.95e-1)" "unprognostic (9.56e-3)" "unprognostic (3.03e-1)" 4.4 2.9 12.8 1.1 14.6 0.5 3.5 12.7 15.5 3.1 12.8 2.5 0.3 2.5 5.0 1.7 4.8 1.3 4.8 13.5 13.6 6.5 9.6 2.6 0.9 13.8 14.4 3.2 2.9 3.2 8.1 2.8 13.8 4.5 0.8 5.7 2.6 1.7 6.4 1.2 1.4 1.6 12.1 1.3 2.2 6.2 14.0 1.3 14.2 2.9 0.6 3.6 2.7 14.1 4.1 3.1 4.8 3.4 11.1 3.9 5.0 2.1 0.9 1.8 0.3 0.3 4.7 0.6 4.1 0.9 4.1 3.3 3.0 1.3 2.7 1.4 5.3 0.7 1.5 3.1 3.9 3.0 2.6 4.7 5.9 2.8 2.6 5.3 1.9 5.9 3.6 0.3 2.5 4.5 4.1 13.4 2.3 3.2 1.7 11.7 1.0 1.9 7.3 1.6 3.8 3.7 2.4 1.0 4.1 5.1 1.1 4.7 2.1 0.8 1.7 2.2 1.7 2.6 3.3 5.4 2.4 2.1 2.0 0.9 0.4 0.3 1.2 0.3 1.3 1.6 0.8 0.4 1.1 1.5 1.2 0.7 0.3 1.7 0.4 1.8 0.2 1.0 12.8 14.6 12.7 15.5 13.5 13.6 13.8 14.4 13.8 12.1 14.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC092718.7 ENSG00000284512 "Novel protein" 16 81022316-81096284 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.9;testis: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" HPA041368 Uncertain Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" Vesicles "HPA041368: AB_10804001" 0.1 0.2 2.7 0.3 3.5 1.1 0.2 2.9 3.5 0.2 2.1 0.1 0.1 0.3 0.2 0.1 0.2 0.1 0.1 2.4 2.5 0.2 0.2 0.1 0.2 2.9 3.0 0.3 0.2 0.3 0.3 0.2 2.8 1.3 0.0 0.7 0.1 0.1 0.1 0.2 0.1 0.0 2.7 0.1 0.1 6.5 2.8 0.0 0.5 0.0 0.0 0.1 0.1 3.9 0.4 0.2 0.6 0.5 0.1 0.0 0.5 0.8 0.1 0.1 0.0 0.4 0.6 0.6 0.3 0.2 0.3 0.9 0.0 0.0 0.1 0.1 0.4 0.3 1.0 0.6 0.0 0.6 1.1 0.2 0.0 0.1 0.0 0.3 0.0 0.7 0.3 1.0 0.0 1.3 0.6 1.4 0.6 0.2 0.4 0.5 0.4 0.1 0.0 0.3 0.9 0.2 0.6 0.3 0.1 0.3 0.4 0.2 0.1 0.5 0.6 0.4 0.3 0.5 0.3 1.2 0.2 0.3 0.2 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.3 0.1 0.2 0.2 0.2 0.1 0.4 0.3 0.1 2.7 3.5 2.9 3.5 2.4 2.5 2.9 3.0 2.8 2.7 2.8 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC118553.2 ENSG00000283761 "Novel protein" 1 99970011-100083321 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 4.1;Collecting duct cells: 1.8;Respiratory ciliated cells: 5.1" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA073681 Approved Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA073681: AB_2686625" 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.2 0.2 0.5 0.2 0.2 0.2 0.1 0.6 0.2 0.1 0.1 0.2 0.3 0.3 0.2 0.7 0.0 0.3 0.2 0.3 0.0 1.0 0.0 0.2 0.4 0.2 0.3 1.0 0.2 0.5 0.1 0.1 0.1 0.4 0.1 0.0 0.2 0.4 0.2 0.7 0.1 0.3 0.2 0.6 0.1 0.3 0.5 0.7 0.9 0.2 0.0 0.6 0.8 1.3 0.5 1.3 2.7 0.5 2.0 0.1 3.3 2.0 2.7 2.1 2.6 0.9 1.7 0.9 1.3 2.2 3.7 0.1 0.2 0.5 0.5 0.0 0.8 2.5 2.2 0.7 1.6 0.3 1.8 1.2 0.7 1.2 2.3 0.1 0.1 2.1 1.1 0.5 2.0 0.9 0.7 1.1 0.6 0.7 1.1 0.6 0.5 0.8 0.6 0.1 0.5 0.8 1.3 0.7 1.4 0.7 2.9 0.3 1.0 1.0 0.3 8.4 5.1 3.5 4.4 5.2 5.0 2.8 4.5 5.2 5.8 1.9 4.2 3.6 0.8 6.7 3.2 4.6 5.9 5.0 0.0 0.3 0.1 0.2 0.2 0.3 0.3 0.2 0.4 0.1 0.2 0.3 0.3 6.4 4.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 1.3 1.8 0.0 0.0 0.6 0.0 0.0 0.2 0.0 1.2 1.3 0.4 0.0 0.0 0.0 0.7 0.0 0.4 0.0 1.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.0 0.0 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 265.1;testis: 101.9" "Group enriched" "Detected in many" 20 "Early spermatids: 543.6;Late spermatids: 1322.9;Proximal enterocytes: 1172.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC TERT1: 63.3;HUVEC TERT2: 33.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" NA NA 104000000 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 13.4 4.9 1.7 4.8 8.1 0.1 8.1 0.2 2.5 18.1 0.5 11.2 176.4 8.1 3.5 4.1 6.3 8.2 10.4 1.3 1.0 10.8 1.9 49.0 4.9 1.3 0.9 1.9 6.2 18.7 9.2 11.6 1.3 8.9 6.1 0.4 7.6 23.8 16.1 3.8 265.1 9.6 0.8 2.8 8.3 101.9 2.0 0.8 19.2 10.0 2.1 5.5 3.8 1.1 0.0 0.0 0.0 0.0 2.6 63.3 0.6 2.4 4.7 0.0 0.0 0.9 5.1 1.3 1.8 11.4 0.1 0.0 3.1 0.0 0.0 0.0 1.4 6.6 0.0 0.0 1.4 0.0 0.0 4.2 0.0 0.1 0.0 1.2 33.8 0.0 5.8 0.0 0.1 1.1 0.0 1.4 0.4 11.7 0.7 0.1 0.5 0.9 0.0 0.0 8.2 5.6 0.0 0.0 0.0 1.3 2.9 0.4 0.0 0.1 0.2 0.5 0.1 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.2 1.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 8.1 0.2 2.5 1.3 1.0 1.3 0.9 1.3 0.8 2.0 1.1 50.0 0.0 3.3 0.0 0.5 1.5 2.6 0.1 1.2 4.0 3.6 1.9 2.1 1.5 0.7 0.0 0.0 0.1 0.3 11.9 0.0 5.9 543.6 10.8 8.0 34.7 18.0 0.0 4.7 0.4 0.1 11.5 2.0 36.3 7.0 24.1 3.6 0.8 4.2 0.0 1.8 39.8 0.0 33.7 3.5 1322.9 4.4 13.6 3.6 4.7 0.0 1.8 0.0 1.0 0.2 0.7 40.9 2.6 0.1 4.2 1172.8 21.7 0.0 1.1 0.0 2.0 4.2 13.5 6.4 0.2 0.1 0.1 2.2 0.3 26.2 2.1 ACSBG1 "BG1, BGM, FLJ30320, hBG1, hsBG, KIAA0631, MGC14352" ENSG00000103740 "Acyl-CoA synthetase bubblegum family member 1" Q96GR2 15 78167468-78245688 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 56.6;skin 1: 14.3" "Cell type enriched" "Detected in some" 5 "Astrocytes: 158.0" "Cancer enriched" "Detected in some" 4 "glioma: 3.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "NTERA-2: 3.1;SK-MEL-30: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041642, CAB045955, HPA058869" Approved Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "CAB045955: AB_11124196, HPA041642: AB_2677593, HPA058869: AB_2683840" "unprognostic (1.28e-1)" "unprognostic (1.63e-2)" "unprognostic (1.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.29e-2)" "unprognostic (4.18e-2)" "unprognostic (1.32e-2)" "unprognostic (1.58e-2)" "unprognostic (1.86e-1)" "unprognostic (5.64e-2)" "unprognostic (2.02e-1)" "unprognostic (4.13e-1)" "unprognostic (1.05e-1)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (4.19e-2)" "unprognostic (1.42e-2)" 0.1 5.5 23.0 0.4 42.6 2.4 1.6 30.5 24.0 0.5 0.0 1.1 0.4 0.2 0.7 0.3 2.8 0.2 0.8 19.6 35.9 0.5 0.4 0.5 0.4 46.0 39.9 0.3 0.2 0.0 0.5 0.1 47.7 0.8 0.1 0.6 0.3 0.2 0.2 14.3 0.5 0.2 45.8 0.3 0.3 3.7 36.6 3.4 0.2 0.0 0.1 0.3 0.5 56.6 0.3 0.0 0.6 0.9 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.2 0.2 0.3 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.5 0.3 0.6 0.3 0.0 0.2 0.6 0.2 0.0 0.1 0.1 0.2 0.0 0.4 0.2 0.4 0.0 0.1 0.2 0.5 3.1 0.2 0.1 0.1 0.4 0.2 0.0 0.4 0.2 0.3 0.1 0.4 1.5 0.3 0.1 0.2 0.4 0.2 0.2 0.1 0.1 0.3 0.1 0.3 0.1 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 1.0 0.0 0.3 23.0 42.6 30.5 24.0 19.6 35.9 46.0 39.9 47.7 45.8 36.6 56.6 0.1 0.0 2.0 158.0 0.6 1.1 0.6 0.3 0.6 1.9 0.2 0.1 3.0 0.0 2.7 0.0 4.2 0.2 0.5 0.3 0.0 0.0 1.8 4.4 0.3 0.2 0.0 4.6 0.7 0.0 0.2 0.7 0.5 0.3 0.0 0.1 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.0 0.0 1.7 0.3 4.0 1.8 2.8 0.1 0.2 1.0 7.5 26.9 0.2 0.0 0.0 0.9 0.3 0.1 0.2 19.1 3.3 0.0 0.3 1.0 2.0 10.0 0.4 0.6 0.4 0.5 1.6 0.1 0.7 ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 770.4;liver: 1319.0;skeletal muscle: 731.8" "Cell type enhanced" "Detected in many" "Early spermatids: 355.8;Hepatocytes: 1170.0;Late spermatids: 456.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 475.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 475.2" "Cell line enhanced" "Detected in all" "ASC diff: 1124.0;ASC TERT1: 275.2;HSkMC: 609.5;RPTEC TERT1: 358.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011317, HPA011964" Enhanced Uncertain Vesicles NA NA 44000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA011316: AB_1844536, HPA011317: , HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favorable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" 770.4 43.3 32.5 94.8 43.9 337.9 316.7 45.2 70.2 62.1 60.7 34.0 32.4 41.6 78.2 66.0 50.6 36.2 172.7 34.4 39.1 218.7 1319.0 173.7 20.7 63.2 44.4 15.5 49.3 57.0 39.6 30.0 56.2 91.3 16.3 28.4 84.2 30.1 731.8 173.0 34.5 42.8 45.2 132.8 54.2 41.9 63.2 12.2 51.3 442.0 24.7 73.2 57.7 70.8 51.6 15.9 9.7 24.6 1124.0 275.2 8.3 29.1 13.8 16.1 11.2 3.9 14.0 22.2 3.0 32.8 38.4 29.7 43.1 17.8 13.3 107.1 17.7 16.6 13.1 40.5 183.4 41.9 37.2 609.5 140.7 13.6 67.1 27.6 21.1 3.6 7.5 59.4 77.0 26.9 3.1 55.1 2.0 32.5 23.3 8.0 8.6 27.0 358.4 135.9 36.3 35.1 25.4 70.8 86.5 3.9 26.9 39.8 25.1 13.8 16.8 34.5 8.7 24.5 13.5 8.9 45.6 56.3 22.4 16.5 54.7 17.7 3.3 30.9 2.8 3.3 2.3 1.5 13.1 3.4 2.5 2.2 475.2 4.4 23.0 2.4 4.9 20.8 32.5 43.9 45.2 70.2 34.4 39.1 63.2 44.4 56.2 45.2 63.2 70.8 7.5 25.6 121.0 6.5 15.7 21.0 16.0 14.0 5.2 6.6 49.7 10.3 119.1 25.8 33.5 31.3 18.8 10.2 7.1 4.3 93.9 4.6 355.8 9.8 25.0 9.8 0.0 34.1 15.2 12.8 2.2 19.4 36.2 24.6 24.1 1.5 18.2 1170.0 41.8 3.3 22.8 4.7 85.5 140.7 14.6 456.6 19.3 170.1 32.0 6.5 40.5 3.1 1.0 8.5 89.8 8.6 1.6 16.6 8.6 51.3 1.5 111.1 26.8 11.4 13.1 11.1 12.4 10.5 16.7 26.4 41.1 3.4 10.6 1.8 3.2 23.1 ACSM5 FLJ20581 ENSG00000183549 "Acyl-CoA synthetase medium chain family member 5" Q6NUN0 16 20409534-20441336 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 276.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 237.8" "Group enriched" "Detected in some" 7 "liver cancer: 20.5;renal cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 5.3;ASC TERT1: 11.5;HSkMC: 13.8;U-87 MG: 8.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA041435 Uncertain Uncertain Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA041435: AB_10961121" "unprognostic (1.01e-1)" "unprognostic (1.61e-3)" "unprognostic (3.73e-2)" "unprognostic (1.98e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-2)" "unprognostic (1.84e-2)" "unprognostic (4.64e-3)" "unprognostic (1.64e-1)" "unprognostic (2.01e-2)" "unprognostic (2.15e-2)" "unprognostic (2.33e-1)" "unprognostic (5.11e-3)" "unprognostic (2.09e-2)" "unprognostic (3.85e-2)" "unprognostic (2.78e-2)" "unprognostic (1.57e-1)" 25.5 2.5 7.1 0.6 5.2 0.6 10.7 4.7 5.0 2.8 3.0 3.7 0.8 1.2 7.1 1.0 1.7 2.3 3.3 5.5 7.9 25.4 276.6 2.1 1.9 6.3 6.8 0.8 0.6 1.0 0.5 1.4 6.8 0.6 1.2 0.5 0.9 0.9 13.9 2.3 1.9 1.0 6.7 4.6 3.4 0.9 8.2 0.7 4.2 1.7 0.7 1.1 2.2 8.2 0.0 0.0 0.1 0.1 5.3 11.5 0.0 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 13.8 0.0 0.8 0.1 0.2 0.0 0.0 0.1 0.5 1.6 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 2.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 8.5 0.1 0.0 0.1 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 7.1 5.2 4.7 5.0 5.5 7.9 6.3 6.8 6.8 6.7 8.2 8.2 0.4 0.0 0.0 1.0 0.5 0.0 0.1 0.0 0.0 0.0 0.8 0.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.5 0.5 0.0 0.3 1.2 0.0 13.5 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 6.1 237.8 3.7 0.0 0.2 0.0 0.0 11.7 1.5 0.8 9.3 3.5 0.0 7.5 1.3 0.9 0.0 1.5 0.1 0.0 0.0 6.0 0.0 0.2 0.0 52.1 0.0 0.1 0.0 11.3 0.3 0.2 0.3 0.1 0.6 0.0 0.7 0.9 0.1 0.2 ADAM15 MDC15 ENSG00000143537 "ADAM metallopeptidase domain 15" Q13444 1 155050566-155062775 "Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.5;Extravillous trophoblasts: 172.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 39.1;intermediate monocyte: 26.5;myeloid DC: 64.0" "Group enriched" "Detected in all" 5 "dendritic cells: 64.0;monocytes: 39.1" "Cell line enhanced" "Detected in many" "PC-3: 329.5;RPMI-8226: 361.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011633, HPA072878" Uncertain Uncertain Vesicles NA NA 640000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA011633: AB_1844574, HPA072878: " "unprognostic (6.35e-3)" "unprognostic (1.51e-1)" "unprognostic (1.60e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (5.83e-5)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (2.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.64e-9)" "unprognostic (3.35e-2)" "unprognostic (6.20e-2)" "unprognostic (2.04e-2)" "unprognostic (7.40e-2)" 70.1 18.5 12.5 21.4 16.0 34.1 64.7 16.9 13.9 40.3 7.1 38.3 16.4 42.5 7.6 79.1 41.5 21.6 63.1 10.5 13.8 32.4 15.1 50.0 10.0 20.2 15.1 25.5 25.5 30.0 14.1 39.1 16.8 40.0 23.8 3.4 45.3 16.7 22.7 107.9 31.3 38.6 17.3 28.8 44.2 4.9 17.1 7.3 31.6 32.4 13.6 38.9 57.3 18.0 112.0 35.0 7.0 153.2 54.9 45.6 66.3 48.2 60.9 60.1 40.5 25.9 63.3 30.9 210.7 63.5 26.7 135.9 34.5 147.9 15.8 14.3 44.9 7.6 63.1 25.3 95.5 63.4 7.9 48.7 153.8 60.5 86.6 82.6 274.7 9.3 11.9 124.8 45.2 64.7 0.5 47.1 21.6 193.4 329.5 10.0 20.5 361.8 43.7 29.7 20.8 44.7 105.2 131.2 41.8 10.7 194.8 38.9 205.1 58.6 24.6 58.9 54.1 13.9 11.7 13.7 42.7 47.6 65.4 0.0 39.1 0.8 9.5 26.5 6.5 2.0 4.7 5.6 64.0 2.1 2.0 2.5 1.4 1.6 6.2 5.3 8.9 22.8 12.5 16.0 16.9 13.9 10.5 13.8 20.2 15.1 16.8 17.3 17.1 18.0 164.5 3.2 6.7 8.8 6.6 48.9 30.4 81.6 47.8 9.7 34.6 20.7 11.5 35.8 38.3 9.2 29.2 13.0 8.1 100.4 0.0 33.4 1.7 13.3 9.2 120.8 12.7 4.6 8.1 25.5 172.4 19.8 85.6 15.4 1.3 8.5 62.2 19.9 31.7 6.7 9.8 80.7 18.3 65.0 43.6 1.3 17.4 27.2 14.2 15.9 28.8 8.8 13.4 9.0 16.8 42.1 50.9 18.0 8.0 55.2 47.4 2.6 22.9 17.0 13.1 15.7 14.5 0.8 6.4 91.2 57.1 17.8 8.6 2.7 76.9 40.0 ADAM19 MLTNB ENSG00000135074 "ADAM metallopeptidase domain 19" Q9H013 5 157395534-157575775 "Plasma proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 56.7;Cone photoreceptor cells: 62.6;Extravillous trophoblasts: 81.8;Langerhans cells: 49.3;monocytes: 83.5;Plasma cells: 53.8;Rod photoreceptor cells: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 128.3;eosinophil: 139.9;memory B-cell: 50.8;naive B-cell: 53.5;neutrophil: 70.5;plasmacytoid DC: 66.8" "Group enriched" "Detected in many" 5 "B-cells: 53.5;dendritic cells: 66.8;granulocytes: 139.9" "Cell line enhanced" "Detected in many" "HDLM-2: 109.7;U-251 MG: 206.5" "Low region specificity" "Detected in all" HPA055537 Approved Vesicles NA NA 17000 "Cluster 2: Granulocytes - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Vesicles "HPA055537: AB_2797253" "unprognostic (4.71e-1)" "unprognostic (1.01e-1)" "unprognostic (1.77e-1)" "unprognostic (4.64e-2)" "unprognostic (1.81e-3)" "unprognostic (2.63e-1)" "unprognostic (2.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.76e-2)" "unprognostic (2.80e-1)" "unprognostic (1.42e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.90e-12)" "unprognostic (1.44e-1)" "unprognostic (4.38e-2)" "unprognostic (2.22e-1)" "unprognostic (1.11e-2)" 4.9 3.6 2.6 24.0 3.3 7.7 2.7 5.3 4.6 4.9 0.4 22.8 5.8 8.0 2.6 5.1 7.4 8.9 24.7 3.1 3.8 2.1 9.6 13.2 29.0 5.1 4.5 3.5 0.9 0.1 1.8 13.1 4.7 7.6 6.7 22.6 1.9 6.3 6.5 1.4 18.7 16.3 3.1 22.6 9.6 1.6 4.5 7.4 4.2 2.8 30.2 18.8 5.2 3.9 38.8 6.0 11.5 0.1 0.8 0.7 73.7 45.0 16.0 27.5 20.5 19.9 30.7 19.9 2.4 23.4 5.7 32.4 1.8 2.9 24.9 109.7 1.1 0.1 3.3 2.7 6.5 0.1 0.0 5.2 0.1 21.5 4.3 32.7 31.5 0.0 5.7 2.8 59.4 0.0 0.0 0.1 12.3 0.0 19.3 0.6 65.9 16.8 2.9 0.6 5.2 3.5 0.0 15.9 2.3 45.3 0.2 0.6 48.7 29.6 31.7 6.8 206.5 11.8 0.4 69.6 6.7 0.1 13.5 128.3 13.1 139.9 1.5 1.2 3.5 50.8 14.4 3.3 4.2 53.5 0.4 0.4 70.5 0.4 0.1 66.8 16.6 9.2 2.6 3.3 5.3 4.6 3.1 3.8 5.1 4.5 4.7 3.1 4.5 3.9 1.5 6.4 0.6 2.0 56.7 2.2 0.1 1.2 0.0 37.7 0.5 0.4 5.6 0.0 0.7 3.7 62.6 1.1 22.0 0.1 0.0 0.5 4.1 0.5 6.8 5.6 0.0 1.7 24.2 1.5 81.8 6.5 0.5 0.2 0.0 0.3 4.2 7.5 1.7 15.2 21.2 0.1 0.0 9.0 49.3 1.3 5.6 12.4 1.8 10.3 83.5 2.4 1.0 13.0 28.7 2.2 0.1 7.9 53.8 0.2 0.0 0.1 0.1 43.9 6.6 12.3 13.3 0.0 1.1 2.5 1.4 8.3 24.0 1.7 0.3 0.2 ADAMTS13 "C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP" ENSG00000160323 "ADAM metallopeptidase with thrombospondin type 1 motif 13" Q76LX8 9 133414358-133459402 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 63.8" "Cell type enhanced" "Detected in many" "Astrocytes: 16.0;Early spermatids: 19.3;Excitatory neurons: 12.4;Inhibitory neurons: 12.4;Late spermatids: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042014, HPA042844, HPA052077" Approved Approved Vesicles "Secreted to blood" NA NA 1300000000 120000000 "Cluster 34: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA042014: AB_2677798, HPA042844: AB_2678200, HPA052077: " "unprognostic (1.09e-1)" "unprognostic (1.45e-1)" "unprognostic (8.75e-4)" "unprognostic (1.49e-2)" "unprognostic (1.83e-1)" "unprognostic (3.02e-1)" "unprognostic (4.76e-2)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.88e-1)" "unprognostic (4.52e-5)" "unprognostic (1.11e-1)" "unprognostic (9.91e-2)" "unprognostic (4.78e-2)" "unprognostic (3.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.30e-3)" 2.5 2.8 6.9 0.5 7.3 0.6 2.8 7.6 10.0 5.0 5.3 4.3 3.2 4.2 2.9 2.4 5.7 1.2 6.0 7.1 6.2 9.6 63.8 2.8 0.9 7.0 6.7 6.7 6.2 1.5 12.5 0.8 7.1 6.4 0.9 1.1 2.5 1.4 4.3 2.6 4.4 0.6 6.3 2.6 9.8 13.5 7.2 0.8 6.1 1.4 0.5 4.4 3.1 7.1 0.0 0.8 1.9 2.6 1.5 1.3 0.8 0.7 0.5 0.2 0.3 0.3 2.1 0.2 0.9 0.4 0.6 0.3 0.1 0.4 0.1 1.2 1.7 0.2 0.9 0.4 1.1 0.0 0.7 3.6 0.9 0.2 0.7 1.2 0.1 1.3 0.0 0.8 0.3 3.3 0.0 0.9 2.0 1.1 1.1 0.2 0.2 0.9 0.8 0.8 1.3 4.0 1.4 0.6 1.2 3.9 3.7 0.4 0.5 1.5 0.8 0.9 0.0 1.7 0.3 0.3 1.1 0.2 1.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 7.3 7.6 10.0 7.1 6.2 7.0 6.7 7.1 6.3 7.2 7.1 0.9 0.0 2.0 16.0 1.2 0.3 0.3 0.9 0.0 1.7 1.4 1.9 4.2 4.3 2.4 0.0 0.0 0.2 0.2 1.0 1.9 0.6 19.3 3.6 1.6 0.9 1.2 0.0 12.4 0.4 0.3 1.5 4.6 3.3 0.0 3.0 5.0 1.6 0.2 3.3 12.4 1.3 0.0 0.6 0.0 13.6 0.9 0.3 0.0 7.5 0.0 1.7 0.0 2.0 5.5 0.3 3.0 1.5 0.4 0.4 1.5 0.9 0.7 1.8 0.0 0.4 0.7 6.0 3.9 0.3 0.4 0.1 0.5 1.7 0.9 0.3 ADAMTS7 "ADAM-TS7, DKFZp434H204" ENSG00000136378 "ADAM metallopeptidase with thrombospondin type 1 motif 7" Q9UKP4 15 78759206-78811464 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 30.6" "Cell type enriched" "Detected in some" 4 "Theca cells: 44.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "HMC-1: 259.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA045284, HPA048453" Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA045284: AB_2679285, HPA048453: AB_2680399" "unprognostic (5.94e-3)" "unprognostic (9.94e-3)" "unprognostic (2.76e-2)" "unprognostic (7.09e-2)" "unprognostic (3.38e-1)" "unprognostic (1.93e-1)" "unprognostic (5.88e-4)" "unprognostic (3.34e-3)" "unprognostic (2.89e-2)" "unprognostic (3.31e-2)" "unprognostic (1.83e-2)" "unprognostic (3.79e-1)" "unprognostic (1.34e-2)" "prognostic unfavorable (9.53e-4)" "unprognostic (1.59e-1)" "unprognostic (2.66e-2)" "unprognostic (8.86e-2)" 6.6 5.3 0.5 1.8 0.4 0.1 3.8 0.3 0.5 6.0 0.6 4.2 1.1 7.2 0.1 0.9 2.2 2.3 30.6 0.4 0.5 2.2 1.1 6.3 0.9 0.5 0.5 6.1 0.5 0.4 0.8 2.1 0.4 1.8 0.2 0.5 1.3 0.4 1.1 1.8 2.6 1.4 0.2 5.2 2.2 4.1 0.7 0.1 2.1 0.5 0.2 3.0 2.5 0.6 0.0 1.1 16.5 7.5 6.9 8.2 20.9 3.7 1.3 1.0 0.6 0.0 0.1 0.0 4.8 0.4 1.0 0.4 0.4 2.0 0.0 0.3 0.6 2.1 0.5 0.1 6.9 0.0 259.9 3.3 2.0 1.9 1.0 5.3 24.0 0.0 0.3 0.7 5.6 0.0 0.1 4.9 4.7 0.0 1.4 17.3 7.7 0.3 0.5 0.9 0.3 23.9 4.8 0.0 0.6 4.0 3.2 0.4 29.8 9.4 1.0 3.3 0.0 0.1 0.0 0.0 1.6 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.3 0.5 0.4 0.5 0.5 0.5 0.4 0.2 0.7 0.6 7.5 0.0 0.0 3.6 0.3 0.4 0.2 0.7 0.0 0.3 0.1 0.5 9.8 0.0 0.3 0.0 0.0 0.3 0.2 0.1 0.0 0.1 4.9 0.8 7.5 10.5 0.0 0.0 0.1 0.0 0.3 10.1 0.5 0.9 3.8 7.2 2.9 0.3 0.7 0.0 0.2 0.0 2.0 0.0 0.8 2.7 1.5 0.1 1.8 1.0 0.1 1.3 0.0 9.5 1.4 0.3 0.0 1.9 0.0 0.3 0.0 0.1 0.3 0.1 0.0 3.7 5.0 2.6 2.0 0.2 0.1 0.3 0.5 44.9 0.1 0.3 ADAMTSL1 "ADAMTSR1, C9orf94, FLJ35283" ENSG00000178031 "ADAMTS like 1" Q8N6G6 9 17906563-18910950 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 13.3" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 245.4" "Cancer enhanced" "Detected in many" "prostate cancer: 2.6" "Region enhanced" "Detected in many" "thalamus: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 118.3;HSkMC: 61.2;hTEC/SVTERT24-B: 64.3;hTERT-RPE1: 55.8;LHCN-M2: 64.3;TIME: 207.9;U-138 MG: 96.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057437, HPA074973" Uncertain Approved Vesicles "Secreted in other tissues" NA NA 28000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA057437: AB_2683440, HPA074973: " "unprognostic (4.64e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-2)" "unprognostic (7.21e-2)" "unprognostic (2.45e-3)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (7.77e-2)" "unprognostic (2.01e-4)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (6.41e-2)" "unprognostic (7.29e-3)" "unprognostic (2.58e-2)" "unprognostic (1.87e-1)" "unprognostic (6.59e-2)" "unprognostic (1.50e-2)" 3.9 5.5 1.0 1.9 0.9 0.0 2.4 1.7 1.1 3.8 0.0 3.0 1.8 13.3 1.1 5.4 4.0 4.9 1.0 3.6 1.8 2.1 0.9 1.2 0.8 2.1 3.3 1.5 1.4 0.2 1.8 0.6 0.5 8.1 2.9 0.4 1.3 1.6 0.4 0.9 1.8 11.2 1.4 0.7 5.1 1.0 9.6 0.5 0.9 0.8 0.9 2.6 2.0 1.0 6.4 0.5 1.2 0.0 17.5 118.3 0.0 3.6 16.3 14.8 33.3 0.0 0.1 0.1 0.1 44.1 5.5 0.0 6.6 1.1 41.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 61.2 0.0 64.3 0.2 55.8 27.1 0.0 0.1 0.3 64.3 0.0 0.2 0.1 5.6 0.0 0.3 0.0 10.1 0.2 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 207.9 96.9 2.5 2.6 15.8 0.0 0.0 0.0 31.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 1.7 1.1 3.6 1.8 2.1 3.3 0.5 1.4 9.6 1.0 1.6 0.0 0.0 5.2 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.4 1.4 0.0 0.6 0.0 0.0 0.0 0.0 3.1 0.0 0.1 7.2 0.3 1.1 8.9 0.0 0.0 245.4 0.0 0.0 15.1 0.5 0.5 0.0 0.1 1.1 0.0 0.1 0.0 39.5 0.4 0.0 0.0 0.8 2.9 5.0 0.1 0.0 1.9 0.0 0.0 0.0 9.0 5.7 0.0 0.4 1.2 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.1 1.2 2.9 1.6 0.1 0.1 0.1 0.0 0.1 1.7 0.1 ADAMTSL2 KIAA0605 ENSG00000197859 "ADAMTS like 2" Q86TH1 9 133532164-133575519 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 73.2;liver: 35.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 5.9;Endothelial cells: 5.7;Fibroblasts: 8.5;Microglial cells: 12.2;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 7.4;RPMI-8226: 10.1;SH-SY5Y: 30.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045634, HPA053812" Approved Approved Vesicles "Secreted in other tissues" NA NA 170000000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA045634: AB_2679399, HPA053812: AB_2682271" "unprognostic (5.10e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.35e-2)" "unprognostic (1.07e-1)" "unprognostic (5.50e-2)" "unprognostic (6.78e-3)" "unprognostic (1.31e-2)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.17e-2)" "unprognostic (7.37e-2)" "unprognostic (1.56e-1)" "unprognostic (3.40e-1)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" 3.7 28.5 6.8 1.0 7.3 0.1 1.5 12.0 10.1 2.3 1.4 2.7 1.4 3.1 3.1 1.8 3.1 2.5 73.2 5.8 7.9 25.9 35.8 23.2 3.4 19.3 11.1 4.9 7.1 1.2 15.9 1.5 20.8 8.4 0.3 0.3 3.4 2.2 4.3 0.8 3.2 0.9 8.5 6.4 2.3 3.1 9.3 0.6 12.1 0.5 0.6 5.3 1.6 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.6 0.5 0.0 1.1 0.7 10.1 0.0 0.0 1.4 30.1 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 7.3 12.0 10.1 5.8 7.9 19.3 11.1 20.8 8.5 9.3 7.6 1.4 0.0 0.5 4.9 0.1 0.1 0.1 0.0 0.0 4.2 0.0 0.1 2.3 0.0 0.0 1.8 0.0 0.1 0.0 1.4 5.9 0.2 0.1 0.1 0.1 5.7 5.3 0.0 5.0 0.0 0.1 8.5 0.0 0.0 0.0 0.1 4.6 0.9 0.3 0.0 3.8 0.4 0.0 0.3 0.8 1.1 4.7 0.6 0.0 12.2 0.0 0.4 0.0 2.5 4.0 0.2 0.5 3.0 0.0 0.2 0.0 0.7 0.0 0.2 6.6 1.1 1.6 0.1 0.8 0.4 0.3 0.0 0.6 0.7 1.1 0.2 ADAMTSL3 "KIAA1233, punctin-2" ENSG00000156218 "ADAMTS like 3" P82987 15 83654088-84039842 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 141.1;Alveolar cells type 2: 111.8;Astrocytes: 86.5;Club cells: 61.7;granulocytes: 63.1;Inhibitory neurons: 91.6;Oligodendrocytes: 75.2;Respiratory ciliated cells: 56.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "EFO-21: 12.1;hTERT-RPE1: 3.6;RPTEC TERT1: 14.0;TIME: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034773, HPA034774" Uncertain Uncertain Vesicles "Secreted in other tissues" NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034773: AB_10601965, HPA034774: AB_2674326" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (2.98e-2)" "unprognostic (1.07e-2)" "unprognostic (1.56e-1)" "unprognostic (9.89e-2)" "unprognostic (4.07e-2)" "unprognostic (3.27e-1)" "unprognostic (9.18e-3)" "unprognostic (5.92e-2)" "unprognostic (9.97e-2)" "unprognostic (3.85e-1)" "unprognostic (8.59e-3)" "unprognostic (5.00e-3)" "unprognostic (4.62e-1)" "unprognostic (8.64e-2)" "unprognostic (3.95e-5)" 6.3 4.2 1.1 1.0 1.7 0.0 1.7 1.4 1.0 3.1 4.4 10.6 1.4 6.9 1.5 3.3 4.4 1.1 10.7 1.1 1.1 3.3 10.4 7.4 1.1 1.4 1.5 1.2 7.3 0.8 1.4 10.4 1.7 6.6 3.2 0.3 2.4 7.1 2.6 1.4 1.8 4.7 1.5 1.9 4.6 2.7 1.1 1.0 2.6 4.8 0.5 5.2 2.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.9 0.0 14.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 0.0 0.0 13.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 1.4 1.0 1.1 1.1 1.4 1.5 1.7 1.5 1.1 3.0 8.7 141.1 111.8 86.5 0.1 7.0 5.2 1.7 0.6 0.2 0.2 0.3 9.4 0.0 61.7 1.8 0.0 0.1 0.8 0.0 0.0 0.5 14.9 0.6 0.4 10.6 0.0 0.0 31.3 2.4 0.2 29.0 1.5 1.2 63.1 0.1 1.1 10.2 0.2 6.7 91.6 0.0 0.0 0.6 0.5 16.9 49.4 5.9 0.0 5.6 0.0 0.1 1.0 4.5 75.2 1.0 0.0 17.0 0.4 2.4 0.0 0.6 56.4 0.2 26.3 13.0 8.3 2.1 2.8 0.6 1.1 0.1 5.0 0.4 0.0 2.3 ADCYAP1R1 "PAC1, PAC1R, PACAPR" ENSG00000078549 "ADCYAP receptor type I" P41586 7 31052308-31111479 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 148.0" "Group enriched" "Detected in some" 4 "Astrocytes: 57.1;Inhibitory neurons: 45.7" "Cancer enriched" "Detected in some" 11 "glioma: 45.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.7;NTERA-2: 4.8;SCLC-21H: 4.1;SH-SY5Y: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030739, HPA049877" Enhanced Enhanced Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA030739: AB_2732461, HPA049877: AB_2680928" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.16e-2)" "prognostic favorable (5.78e-4)" "unprognostic (2.17e-1)" "unprognostic (8.36e-2)" "unprognostic (4.93e-2)" "unprognostic (5.75e-2)" "unprognostic (3.50e-2)" "unprognostic (3.88e-1)" "unprognostic (1.58e-1)" "unprognostic (6.67e-3)" "unprognostic (6.43e-4)" "unprognostic (1.09e-3)" "unprognostic (9.55e-2)" "unprognostic (3.85e-2)" "unprognostic (2.75e-4)" 7.4 11.4 91.8 2.3 79.8 0.0 4.0 53.4 57.6 13.1 3.5 7.1 0.8 5.3 1.5 2.9 29.5 1.3 3.8 69.7 106.5 0.1 0.2 0.8 0.1 96.0 102.7 1.8 1.6 1.6 9.8 0.0 88.9 1.8 1.3 2.7 2.2 3.2 1.3 1.1 2.2 3.7 67.9 0.5 3.5 1.6 148.0 0.8 2.1 8.0 0.8 1.8 4.3 43.7 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 7.4 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.6 0.8 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 91.8 79.8 53.4 57.6 69.7 106.5 96.0 102.7 88.9 67.9 148.0 43.7 4.2 0.0 0.0 57.1 0.0 0.5 0.0 0.0 0.0 1.7 0.2 0.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.2 0.7 0.0 0.0 10.8 0.0 0.0 4.6 0.0 6.3 0.0 1.2 0.0 0.0 0.0 0.0 45.7 0.0 0.0 0.0 0.7 0.9 11.5 0.0 1.8 2.8 0.0 0.0 0.0 11.6 1.5 0.0 0.0 5.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 5.8 0.3 1.5 0.0 0.3 0.0 0.2 0.1 0.0 0.1 ADHFE1 FLJ32430 ENSG00000147576 "Alcohol dehydrogenase iron containing 1" Q8IWW8 8 66432492-66468907 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 31.2;skeletal muscle: 29.2;tongue: 31.3" "Cell type enhanced" "Detected in many" "Astrocytes: 76.4;Cardiomyocytes: 41.6;Syncytiotrophoblasts: 116.4" "Cancer enhanced" "Detected in many" "liver cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.2;RPTEC TERT1: 1.5" "Low region specificity" "Detected in all" HPA023062 Enhanced Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA023062: AB_1844611" "prognostic favorable (5.76e-5)" "unprognostic (8.69e-2)" "unprognostic (6.71e-2)" "unprognostic (2.70e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "prognostic favorable (9.90e-5)" "unprognostic (7.76e-3)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (9.43e-2)" "prognostic favorable (4.55e-5)" "unprognostic (1.37e-2)" "unprognostic (2.06e-1)" "unprognostic (4.66e-2)" "unprognostic (5.94e-3)" 7.0 2.3 8.7 0.3 8.5 0.0 3.9 7.2 11.7 2.3 10.4 3.9 0.6 2.0 1.3 1.3 5.6 0.7 24.5 8.2 8.2 6.6 31.2 2.1 0.3 8.3 8.5 5.1 9.4 5.0 2.6 1.1 8.1 5.2 0.7 1.5 2.3 1.5 29.2 1.1 2.5 0.2 7.8 1.8 11.0 1.7 8.7 0.3 2.7 31.3 0.3 4.4 1.8 8.5 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.0 0.2 0.0 0.5 0.1 0.0 0.3 0.0 0.4 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.0 8.7 8.5 7.2 11.7 8.2 8.2 8.3 8.5 8.1 7.8 8.7 8.5 1.5 9.6 20.1 76.4 1.8 1.0 4.1 2.7 3.4 1.7 4.6 4.6 41.6 14.3 9.6 9.2 10.4 8.8 6.5 1.0 11.7 1.5 0.5 2.5 1.6 3.3 3.6 2.5 8.3 0.6 0.9 5.3 8.6 2.5 8.8 6.1 6.1 27.1 2.5 0.0 13.2 2.0 4.1 2.1 2.8 1.6 23.9 2.1 0.0 14.0 2.0 7.6 6.2 21.6 19.2 0.9 5.8 27.1 3.0 3.5 4.1 14.8 14.3 8.5 0.0 7.8 5.2 0.5 0.6 1.9 1.0 116.4 10.0 2.5 2.4 2.5 AGFG1 "HRB, RAB, RIP" ENSG00000173744 "ArfGAP with FG repeats 1" P52594 2 227472152-227561217 "Predicted intracellular proteins" "Differentiation, mRNA transport, Spermatogenesis, Transport" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 333.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008741 Approved Supported Vesicles NA NA 120000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA008741: AB_1850752" "unprognostic (5.76e-2)" "prognostic unfavorable (7.13e-4)" "unprognostic (8.73e-3)" "unprognostic (6.31e-3)" "prognostic favorable (6.10e-4)" "unprognostic (9.30e-3)" "prognostic unfavorable (7.31e-6)" "prognostic unfavorable (1.85e-4)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.43e-5)" "unprognostic (2.03e-2)" "unprognostic (5.78e-2)" "prognostic unfavorable (6.92e-4)" "unprognostic (1.25e-1)" "unprognostic (2.37e-1)" "unprognostic (1.98e-1)" "unprognostic (4.24e-3)" 69.4 39.4 30.4 48.4 31.6 155.5 51.1 29.3 36.0 25.3 23.8 32.2 43.4 25.7 20.1 47.2 27.3 38.9 36.2 32.4 27.0 36.9 36.2 54.6 47.1 34.6 29.0 26.1 35.0 41.6 17.9 75.8 33.4 21.0 33.0 47.7 27.9 23.4 33.9 36.3 36.2 39.3 33.6 46.5 33.2 92.8 34.5 48.6 34.3 38.6 53.3 65.7 32.2 47.3 60.5 97.9 50.8 49.6 84.8 62.1 191.6 78.4 74.6 92.0 81.2 77.4 67.6 42.7 58.3 86.8 123.8 62.2 87.9 101.7 118.6 72.3 48.9 94.1 80.8 144.3 90.9 64.7 57.0 38.3 106.4 116.7 109.5 70.3 93.7 43.3 100.3 112.0 111.8 85.8 77.8 58.0 79.3 80.4 50.4 70.8 83.6 30.3 91.7 81.5 47.0 36.7 64.1 82.5 74.7 87.6 35.3 72.4 92.7 78.8 63.0 114.7 70.0 64.5 46.9 59.6 85.6 54.4 92.5 4.1 5.3 1.9 1.6 4.3 3.2 2.0 1.8 1.5 3.3 3.5 1.5 2.8 5.6 1.1 4.2 2.3 2.3 1.6 30.4 31.6 29.3 36.0 32.4 27.0 34.6 29.0 33.4 33.6 34.5 47.3 36.6 25.6 23.6 45.7 27.2 33.1 37.5 18.0 18.2 37.7 29.3 22.1 23.3 17.2 19.6 22.0 25.0 31.0 26.5 28.2 15.6 17.5 162.3 32.7 34.9 29.1 34.1 13.3 114.2 21.5 17.5 26.8 39.8 65.8 12.7 30.4 23.6 22.9 24.1 43.7 74.9 20.4 12.2 92.8 33.6 333.2 15.5 67.3 19.6 119.9 48.4 43.3 19.6 109.6 116.0 32.6 18.0 11.7 22.7 39.4 31.3 27.4 15.5 35.4 19.7 83.8 21.7 72.6 18.4 25.0 32.1 39.7 24.0 20.6 22.2 57.9 AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200317-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 122.5" "Cell type enhanced" "Detected in some" "Hepatocytes: 83.0;Oligodendrocyte precursor cells: 33.7;Oligodendrocytes: 38.5;Proximal enterocytes: 30.5;Proximal tubular cells: 16.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 15.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.4" "Cell line enhanced" "Detected in some" "HSkMC: 3.5;Karpas-707: 7.7;NTERA-2: 3.5;SCLC-21H: 3.2;TIME: 4.0;WM-115: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057900 Uncertain Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA057900: " "unprognostic (2.82e-1)" "unprognostic (9.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.44e-4)" "unprognostic (7.52e-2)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (6.56e-2)" "unprognostic (3.31e-1)" "unprognostic (3.35e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 2.8 0.1 0.9 0.6 2.4 0.1 1.8 0.7 1.9 0.1 0.1 1.2 9.7 0.1 14.5 0.1 0.1 3.6 0.4 0.7 1.4 8.9 122.5 0.2 0.5 1.5 1.4 0.1 0.1 0.0 0.4 0.8 1.5 0.0 0.6 0.1 0.2 0.1 0.3 0.2 14.9 0.1 0.9 0.0 0.3 3.0 1.8 0.2 0.4 0.4 0.1 1.2 0.1 4.1 0.0 2.2 0.0 1.9 0.2 2.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 1.2 0.0 0.7 3.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 4.0 1.3 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 15.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.9 2.4 0.7 1.9 0.7 1.4 1.5 1.4 1.5 0.9 1.8 4.1 10.0 0.0 0.0 6.8 0.3 0.1 0.1 0.7 0.0 0.0 0.2 0.3 0.1 11.5 0.4 3.7 0.0 0.1 0.1 0.5 0.0 0.0 1.3 0.3 0.1 1.2 1.8 2.7 1.3 0.0 0.2 1.2 0.0 0.0 0.0 0.0 1.1 83.0 0.1 0.0 1.7 0.4 0.0 1.6 0.5 1.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 33.7 38.5 0.9 0.1 0.0 0.0 0.0 30.5 16.9 0.3 0.0 6.6 0.4 2.4 1.7 6.4 0.1 0.0 0.1 0.2 0.1 0.6 0.0 AGTR1 "AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R" ENSG00000144891 "Angiotensin II receptor type 1" P30556 3 148697784-148743008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 96.6;placenta: 141.6" "Cell type enhanced" "Detected in some" "Fibroblasts: 53.1;Hepatocytes: 30.9;Leydig cells: 145.1;Sertoli cells: 144.7;Smooth muscle cells: 71.2" "Group enriched" "Detected in many" 8 "breast cancer: 9.6;liver cancer: 9.8;prostate cancer: 6.8;renal cancer: 2.8" "Region enhanced" "Detected in some" "midbrain: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 176.8;ASC TERT1: 24.4;BJ hTERT+ SV40 Large T+: 34.8;HBF TERT88: 53.9;HSkMC: 32.2" "Low region specificity" "Detected in all" HPA003596 Enhanced Uncertain Vesicles NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA003596: AB_1845163" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.48e-4)" "unprognostic (5.28e-3)" "unprognostic (1.55e-1)" "unprognostic (3.46e-1)" "unprognostic (1.28e-2)" "unprognostic (3.26e-2)" "unprognostic (3.08e-2)" "unprognostic (9.25e-3)" "unprognostic (4.11e-2)" "unprognostic (4.79e-2)" "unprognostic (3.21e-3)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (5.41e-3)" 65.9 38.2 0.3 1.8 0.7 0.0 39.9 0.2 0.4 3.4 0.4 21.1 0.8 3.5 2.7 2.8 9.8 6.2 10.9 0.4 1.4 18.4 96.6 10.4 0.7 2.1 8.1 3.8 3.5 2.8 3.8 141.6 0.9 5.3 4.4 0.9 4.7 4.2 11.6 15.8 4.3 4.6 0.2 9.1 6.5 2.2 0.7 3.0 14.2 13.8 0.2 14.6 6.1 0.2 0.0 1.0 0.8 0.0 176.8 24.4 0.0 0.2 3.9 34.8 20.0 0.0 0.0 0.0 0.0 2.6 0.2 0.0 0.0 0.0 53.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 32.2 0.0 3.4 1.8 1.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.2 0.4 0.4 1.4 2.1 8.1 0.9 0.2 0.7 0.2 20.5 0.0 0.6 0.0 0.0 3.4 0.2 0.0 0.0 0.0 1.3 0.9 6.3 2.8 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.1 0.8 0.0 0.3 3.8 23.5 0.0 0.1 7.6 0.3 53.1 0.5 0.0 0.0 0.0 17.5 30.9 0.7 0.0 0.0 0.2 0.0 0.3 3.5 1.7 145.1 0.5 1.8 2.8 0.0 5.7 0.0 0.0 0.1 0.5 0.0 7.5 0.4 1.1 0.0 0.1 0.0 0.1 144.7 7.6 71.2 0.0 1.8 0.3 1.7 0.3 0.5 0.3 0.0 0.1 AGXT "AGT, AGT1, AGXT1, PH1, SPAT, SPT" ENSG00000172482 "Alanine--glyoxylate and serine--pyruvate aminotransferase" P21549 2 240868824-240880502 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 315 "liver: 2199.2" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 2037.9" "Cancer enriched" "Detected in some" 425 "liver cancer: 253.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035370, HPA035371" Enhanced Supported Vesicles NA NA 4700000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA035370: AB_10673218, HPA035371: AB_2674593" "unprognostic (3.14e-2)" "unprognostic (2.58e-1)" "unprognostic (3.37e-4)" "unprognostic (1.04e-1)" "unprognostic (1.23e-2)" "unprognostic (9.56e-2)" "prognostic favorable (5.92e-5)" "unprognostic (8.28e-2)" "unprognostic (2.77e-1)" "unprognostic (5.39e-2)" "unprognostic (1.55e-1)" "unprognostic (7.57e-3)" "unprognostic (2.54e-1)" "unprognostic (9.22e-2)" "unprognostic (1.37e-1)" "unprognostic (3.26e-2)" 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.9 2199.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 44.3 0.1 7.3 0.0 0.7 0.0 7.6 23.5 0.1 0.1 0.2 0.0 2.8 9.0 128.4 0.0 1.7 26.7 0.4 0.0 0.4 0.0 0.0 52.5 2037.9 0.2 0.0 0.0 8.1 4.1 53.5 0.0 1.6 0.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 12.8 0.4 0.0 0.8 1.9 343.9 0.1 0.0 0.0 2.7 0.1 0.1 0.0 0.0 0.0 1.9 5.2 0.1 1.5 0.4 AKAP7 "AKAP15, AKAP18" ENSG00000118507 "A-kinase anchoring protein 7" "O43687, Q9P0M2" 6 131135467-131283535 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 56.6" "Cell type enhanced" "Detected in many" "Astrocytes: 88.8;Cholangiocytes: 177.3;Oligodendrocyte precursor cells: 123.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 27.2;RPTEC TERT1: 23.5;RT4: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027172, HPA027200, HPA028327" Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA027172: AB_1844689, HPA027200: , HPA028327: AB_10601353" "unprognostic (2.83e-2)" "unprognostic (2.70e-1)" "unprognostic (2.88e-2)" "unprognostic (1.45e-3)" "unprognostic (4.57e-2)" "unprognostic (1.24e-1)" "unprognostic (1.93e-1)" "unprognostic (2.70e-2)" "unprognostic (4.41e-1)" "unprognostic (1.18e-1)" "unprognostic (3.89e-1)" "unprognostic (1.54e-1)" "unprognostic (1.32e-3)" "unprognostic (2.52e-1)" "unprognostic (6.03e-3)" "unprognostic (2.53e-1)" "prognostic favorable (2.56e-4)" 9.0 56.6 15.8 6.4 16.3 10.9 6.7 17.7 20.7 8.1 11.5 19.1 29.8 6.4 5.7 4.2 6.8 9.9 6.7 16.0 16.7 8.1 24.4 6.6 11.2 15.3 16.2 9.8 42.0 4.0 4.3 4.0 15.3 14.0 18.9 7.6 4.6 6.4 15.9 2.8 16.5 5.9 16.7 9.6 5.3 8.8 17.0 11.9 5.9 14.4 7.6 8.7 5.6 15.8 1.2 2.1 7.8 3.8 4.4 9.0 5.4 3.3 5.3 5.5 7.3 2.8 2.2 0.1 6.1 5.7 4.1 0.1 2.3 3.6 4.0 0.0 3.3 8.0 2.7 12.2 6.1 0.4 2.5 7.8 2.4 3.6 4.6 5.1 5.8 4.6 1.4 11.7 5.3 2.1 3.6 2.1 27.2 0.8 2.9 7.3 5.1 0.1 23.5 27.2 0.1 2.7 4.5 0.4 11.1 4.5 1.8 17.1 2.1 2.5 3.5 7.5 8.3 10.5 0.1 2.0 6.3 8.1 5.9 15.2 1.9 0.3 8.1 3.8 12.8 3.7 11.1 11.0 2.4 5.5 17.6 11.0 0.5 4.4 4.7 0.1 4.3 6.0 15.8 16.3 17.7 20.7 16.0 16.7 15.3 16.2 15.3 16.7 17.0 15.8 11.7 19.2 9.1 88.8 16.4 6.2 6.5 0.8 6.8 22.3 10.1 13.2 10.4 177.3 1.6 5.5 16.7 8.2 18.0 22.1 19.6 35.7 8.2 31.6 13.4 6.5 1.2 63.8 44.7 4.2 10.2 7.4 6.1 35.6 10.8 22.9 9.7 39.9 8.6 8.4 79.1 14.8 10.2 20.8 9.9 2.7 8.4 12.9 1.8 68.4 9.8 38.2 25.7 123.6 62.7 2.2 33.2 5.7 3.4 8.2 13.6 26.5 1.4 13.2 0.0 12.6 6.9 4.6 10.0 7.0 4.1 4.7 23.9 26.0 22.0 4.9 ALCAM "CD166, MEMD" ENSG00000170017 "Activated leukocyte cell adhesion molecule" Q13740 3 105366909-105576900 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Cell adhesion, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 438.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 737.2;Oligodendrocyte precursor cells: 680.1;Oligodendrocytes: 981.1;Respiratory ciliated cells: 318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 29.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 29.6" "Cell line enhanced" "Detected in many" "hTERT-HME1: 393.4;U-138 MG: 473.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002148, HPA010926" Enhanced Uncertain Vesicles "Secreted to blood" NA NA 1600000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "CAB002148: AB_442053, HPA010926: AB_1078449" "unprognostic (6.82e-2)" "unprognostic (2.66e-1)" "unprognostic (2.13e-1)" "unprognostic (2.19e-1)" "unprognostic (9.48e-3)" "unprognostic (2.08e-2)" "unprognostic (1.63e-3)" "unprognostic (3.89e-2)" "unprognostic (1.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.15e-4)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (9.57e-2)" "unprognostic (7.76e-2)" 7.7 32.7 31.3 12.2 48.1 10.5 81.0 42.4 47.2 28.0 14.4 16.6 17.0 15.5 35.4 8.2 49.1 23.3 9.6 32.4 70.6 22.2 47.9 74.1 9.9 50.7 54.9 57.6 32.7 438.9 19.2 12.1 51.7 32.7 14.5 3.6 33.8 39.6 0.8 11.0 17.4 16.2 44.9 6.3 33.4 4.5 45.7 14.2 62.4 5.0 14.5 25.6 6.4 85.0 248.4 93.7 65.9 33.7 97.6 42.7 0.6 197.7 115.1 124.9 173.8 0.8 50.5 17.3 80.3 280.6 68.8 186.5 10.6 157.4 366.1 16.6 16.6 2.4 65.8 4.6 109.6 101.3 0.8 76.0 114.9 159.9 393.4 346.8 139.3 17.9 0.3 28.6 165.9 16.9 14.5 37.0 13.7 79.3 104.8 9.4 5.9 1.0 188.9 27.2 47.5 131.9 20.6 19.6 12.9 25.9 37.7 66.3 291.6 473.7 162.3 20.9 237.2 0.3 0.6 1.8 108.0 21.1 207.4 0.0 4.7 3.5 0.6 2.1 1.9 4.7 1.5 0.9 29.6 3.0 0.3 0.2 5.3 0.6 1.2 10.5 2.4 3.2 31.3 48.1 42.4 47.2 32.4 70.6 50.7 54.9 51.7 44.9 45.7 85.0 4.5 737.2 143.6 238.6 17.9 12.1 22.8 65.8 12.0 3.0 112.4 47.9 10.1 62.9 255.3 16.5 2.1 0.7 19.5 9.1 1.9 18.5 66.5 108.6 20.1 11.9 16.8 6.3 143.0 43.0 0.7 37.0 23.4 158.1 11.4 29.5 3.6 44.1 57.5 1.7 287.0 16.3 46.8 51.0 162.6 60.1 3.7 86.4 24.9 40.3 93.4 1.3 1.0 680.1 981.1 55.2 8.5 6.4 21.8 117.5 9.6 24.2 318.3 0.8 0.0 7.9 21.8 8.1 5.5 30.1 20.2 0.8 8.9 22.8 10.4 105.4 ANAPC1 "APC1, MCPR, TSG24" ENSG00000153107 "Anaphase promoting complex subunit 1" Q9H1A4 2 111611639-111884690 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Cancer-related genes, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036329, HPA036330, HPA042998" Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" Vesicles "HPA036329: AB_10670714, HPA036330: AB_2675065, HPA042998: AB_2678263" "unprognostic (1.74e-1)" "unprognostic (5.04e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.49e-1)" "unprognostic (2.15e-1)" "unprognostic (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.94e-2)" "unprognostic (2.59e-1)" "unprognostic (3.65e-2)" "unprognostic (1.23e-1)" "unprognostic (2.13e-2)" "unprognostic (1.94e-1)" "unprognostic (1.98e-1)" "unprognostic (1.15e-2)" "unprognostic (1.92e-1)" 6.4 4.8 4.1 9.5 5.1 8.3 9.2 4.8 5.1 6.9 9.8 9.9 8.3 8.0 4.9 8.1 7.8 5.8 5.8 4.7 3.6 6.2 5.6 5.4 12.1 4.1 4.1 8.4 6.3 10.4 4.6 7.7 5.1 6.4 10.5 7.9 5.4 6.2 12.2 6.8 6.5 7.6 3.7 7.8 6.6 10.2 4.0 12.6 6.3 9.4 12.4 8.4 5.8 5.2 42.4 31.0 33.1 23.9 14.9 18.4 32.6 25.0 18.8 30.3 26.5 60.4 26.6 72.7 19.9 23.0 36.0 35.4 51.0 28.4 40.4 31.7 31.9 81.6 27.6 37.1 14.3 85.0 27.4 13.8 14.3 44.9 40.8 15.4 29.5 34.9 75.8 30.8 21.5 20.2 51.9 25.5 50.3 18.3 26.1 51.1 39.4 41.1 19.1 41.6 26.2 16.0 26.2 23.9 22.8 21.8 14.1 30.1 20.9 26.5 28.5 21.7 26.9 23.0 52.5 67.1 21.5 36.9 21.9 0.0 2.1 0.6 4.2 2.2 6.1 4.0 3.8 3.6 3.9 3.1 5.4 5.2 0.4 4.8 1.9 1.8 1.8 3.3 4.1 5.1 4.8 5.1 4.7 3.6 4.1 4.1 5.1 3.7 4.0 5.2 14.5 3.2 8.2 17.0 20.3 14.3 20.5 7.6 22.2 11.2 12.1 11.8 7.5 8.6 6.0 3.7 14.6 12.2 25.4 7.2 5.9 5.9 6.6 13.5 13.4 11.0 11.4 17.9 32.5 5.9 12.7 12.0 12.2 11.7 8.2 19.2 8.6 12.8 9.0 20.2 32.6 11.1 14.2 8.4 11.8 8.6 10.2 12.2 7.2 12.2 8.8 7.7 13.4 21.6 31.3 7.1 5.4 9.4 14.4 24.6 5.6 8.8 8.2 16.0 13.1 15.9 11.5 17.3 21.0 18.0 20.2 6.7 21.2 12.2 14.5 23.4 ANKRD13B FLJ25555 ENSG00000198720 "Ankyrin repeat domain 13B" Q86YJ7 17 29589769-29614761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 27.4;Endometrial stromal cells: 24.2;Excitatory neurons: 19.4;Horizontal cells: 16.8;Late spermatids: 44.7;Oligodendrocytes: 17.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 52.0;SH-SY5Y: 57.6;SK-BR-3: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051886, HPA063748" Uncertain Supported Vesicles NA NA "Cluster 43: Testis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA051886: AB_2681652, HPA063748: AB_2685112" "unprognostic (1.61e-1)" "unprognostic (2.01e-1)" "unprognostic (1.27e-1)" "unprognostic (1.66e-2)" "unprognostic (1.53e-1)" "unprognostic (2.45e-1)" "unprognostic (3.10e-4)" "unprognostic (1.84e-1)" "unprognostic (1.84e-1)" "unprognostic (1.03e-2)" "prognostic favorable (7.58e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (5.92e-6)" "unprognostic (9.93e-2)" "unprognostic (1.18e-1)" "unprognostic (3.94e-2)" "unprognostic (5.36e-3)" 12.0 3.7 12.5 1.7 14.3 0.7 7.5 11.9 15.9 16.3 0.0 10.2 0.8 13.6 0.8 6.5 12.0 3.7 10.3 13.9 6.2 2.8 1.2 5.5 1.6 13.4 9.4 15.1 3.7 1.6 14.6 0.9 10.4 7.7 0.6 2.0 4.3 1.8 9.6 7.5 4.5 2.9 7.2 2.6 4.9 18.9 10.8 0.9 5.8 1.3 0.3 10.0 11.6 22.9 6.6 11.5 13.3 35.4 8.2 8.0 5.1 2.0 1.2 1.4 2.7 6.1 1.4 7.4 6.4 2.8 4.9 24.3 7.2 7.8 0.2 14.8 23.5 2.3 22.3 5.3 3.5 2.4 4.6 7.9 10.2 2.2 5.8 6.4 10.1 12.8 6.0 6.1 1.9 5.9 16.0 7.5 11.4 6.8 9.7 33.4 9.5 23.4 3.0 2.2 52.0 57.6 3.9 48.0 4.3 1.2 7.4 4.4 6.7 7.4 7.2 5.2 7.2 11.4 15.7 9.2 5.2 12.1 4.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 14.3 11.9 15.9 13.9 6.2 13.4 9.4 10.4 7.2 10.8 22.9 2.6 0.0 0.0 6.8 0.1 1.7 1.0 0.7 3.4 4.5 1.8 2.7 2.3 0.0 0.4 0.0 2.1 0.1 0.6 0.6 1.9 1.6 27.4 0.9 24.2 2.4 3.0 1.7 19.4 0.6 0.2 5.5 2.6 1.0 0.0 3.8 1.4 0.6 0.1 16.8 14.6 0.8 0.0 0.3 1.6 44.7 14.6 0.3 0.0 0.0 0.0 1.8 0.0 11.1 17.8 0.5 0.0 7.5 0.5 3.2 0.1 0.2 0.0 5.2 0.0 2.4 2.5 6.0 4.7 2.6 1.7 0.1 0.7 1.0 1.1 1.5 ANKRD2 ARPP ENSG00000165887 "Ankyrin repeat domain 2" Q9GZV1 10 97572499-97583884 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 63 "heart muscle: 437.1;skeletal muscle: 981.2;tongue: 823.8" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 218.3" "Cancer enhanced" "Detected in many" "renal cancer: 4.9;testis cancer: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 17.6;BJ hTERT+ SV40 Large T+: 7.3;HaCaT: 13.0;RPTEC TERT1: 17.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040842, HPA040884" Enhanced Enhanced Vesicles NA NA 110000 "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA040842: AB_10963794, HPA040884: AB_10969453" "unprognostic (1.27e-2)" "unprognostic (9.99e-2)" "unprognostic (2.86e-1)" "unprognostic (1.39e-2)" "unprognostic (1.37e-1)" "unprognostic (1.61e-2)" "unprognostic (2.53e-1)" "unprognostic (5.60e-3)" "unprognostic (2.17e-1)" "unprognostic (3.12e-1)" "unprognostic (4.91e-2)" "unprognostic (2.22e-1)" "unprognostic (1.05e-2)" "unprognostic (3.69e-3)" "unprognostic (4.56e-2)" "unprognostic (1.39e-1)" "unprognostic (2.13e-1)" 0.4 0.8 2.5 0.1 2.3 0.0 0.5 2.5 3.7 0.2 2.0 0.3 0.0 0.3 0.3 1.0 0.1 0.3 437.1 2.5 2.7 11.8 0.3 0.8 0.2 2.5 2.4 0.1 0.9 0.0 0.6 0.0 2.5 2.9 0.0 0.3 3.4 0.9 981.2 2.7 0.2 0.2 1.9 0.1 0.2 0.5 2.7 0.0 0.5 823.8 0.1 0.1 0.4 2.5 17.6 5.4 0.0 0.0 0.2 0.0 0.4 0.9 0.0 7.3 4.7 0.3 5.3 0.0 0.6 0.2 0.4 13.0 0.0 4.7 5.0 0.2 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.8 2.1 4.3 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 17.4 0.8 0.0 0.0 0.0 4.4 0.0 0.4 2.1 0.3 0.0 0.1 1.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 2.3 2.5 3.7 2.5 2.7 2.5 2.4 2.5 1.9 2.7 2.5 0.1 0.0 0.0 1.3 0.0 0.1 0.7 1.7 1.2 0.0 0.2 0.4 218.3 2.8 0.2 3.7 0.0 0.2 0.0 0.0 31.3 1.2 0.6 0.1 0.3 1.6 0.0 0.0 1.3 0.2 0.4 1.0 0.0 0.1 0.0 0.7 0.4 0.2 0.1 0.0 1.5 0.0 0.0 0.0 0.4 0.2 0.0 0.3 0.0 0.0 1.6 0.0 0.0 0.5 0.4 0.9 0.0 1.9 0.0 0.1 0.0 19.1 0.0 0.1 0.0 13.6 1.1 2.5 3.5 0.6 0.3 0.3 0.2 0.1 0.0 0.5 ANKRD6 KIAA0957 ENSG00000135299 "Ankyrin repeat domain 6" Q9Y2G4 6 89433152-89633834 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 26.7" "Cell type enhanced" "Detected in many" "Astrocytes: 35.3;Granulosa cells: 53.9;Inhibitory neurons: 54.3;Oligodendrocyte precursor cells: 32.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 15.1;BEWO: 44.9;HAP1: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020693, HPA035694, HPA064642" Approved Enhanced Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "CAB020693: , HPA035694: AB_2674739, HPA064642: AB_2685310" "unprognostic (3.80e-1)" "unprognostic (3.16e-2)" "unprognostic (2.39e-3)" "unprognostic (2.03e-1)" "unprognostic (1.36e-1)" "unprognostic (3.06e-2)" "unprognostic (2.91e-2)" "unprognostic (3.29e-2)" "unprognostic (4.95e-2)" "unprognostic (2.09e-1)" "unprognostic (7.84e-2)" "unprognostic (2.26e-1)" "unprognostic (1.81e-1)" "unprognostic (1.43e-3)" "unprognostic (2.28e-1)" "unprognostic (3.01e-1)" "unprognostic (2.10e-1)" 3.5 1.8 15.3 2.6 16.5 1.4 3.6 24.7 14.8 5.0 10.5 2.8 0.7 5.2 1.8 4.1 9.1 4.7 7.8 13.6 17.6 4.9 4.1 4.9 2.3 11.2 9.7 12.8 3.8 6.5 3.4 3.7 9.5 2.6 0.9 3.0 5.1 1.7 3.8 1.6 1.5 4.0 8.8 1.8 2.2 5.3 26.7 3.8 4.7 3.1 1.7 3.5 2.8 6.7 0.0 2.0 15.1 6.6 0.1 0.7 44.9 0.2 0.2 0.1 1.0 0.5 1.2 0.0 1.5 0.0 7.0 0.0 15.2 8.2 0.6 0.1 10.0 5.5 0.0 0.5 0.2 0.0 2.0 1.0 2.3 0.0 0.0 0.0 1.6 1.4 0.4 3.6 0.0 1.9 0.2 0.6 4.4 0.6 1.5 5.7 0.0 0.0 2.9 8.0 9.5 3.6 1.2 10.7 4.6 9.0 3.1 3.5 0.0 2.3 0.9 0.2 1.3 0.5 0.1 0.0 0.4 0.0 1.8 0.0 0.1 0.9 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 15.3 16.5 24.7 14.8 13.6 17.6 11.2 9.7 9.5 8.8 26.7 6.7 6.8 16.0 19.4 35.3 1.6 0.9 5.6 4.7 10.2 0.9 4.4 4.6 5.7 11.5 6.4 1.8 12.5 3.6 1.3 0.1 11.7 5.9 2.6 12.0 2.9 5.7 1.8 1.7 23.8 11.2 10.8 7.2 5.6 3.9 10.8 53.9 5.0 2.8 2.6 0.0 54.3 0.0 8.2 2.6 2.1 6.1 9.6 2.5 3.6 25.3 2.9 7.2 3.1 32.6 6.6 5.1 0.1 27.8 4.0 2.5 0.0 4.1 8.2 1.7 6.6 3.4 5.2 5.3 5.3 4.3 1.1 1.9 1.5 4.3 0.0 4.9 ANTXR1 "ATR, FLJ10601, FLJ21776, TEM8" ENSG00000169604 "ANTXR cell adhesion molecule 1" Q9H6X2 2 69013176-69249327 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor Hypotrichosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 130.6;Endometrial stromal cells: 78.1;Oligodendrocyte precursor cells: 141.8;Skeletal myocytes: 111.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 367.9;TIME: 240.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054785 Uncertain Vesicles "Intracellular and membrane" NA NA 11000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA054785: " "unprognostic (1.44e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (8.49e-2)" "unprognostic (4.77e-2)" "unprognostic (3.61e-1)" "unprognostic (4.34e-2)" "unprognostic (1.05e-1)" "unprognostic (6.93e-2)" "unprognostic (1.37e-1)" "unprognostic (4.15e-3)" "unprognostic (9.05e-3)" "unprognostic (1.15e-1)" "unprognostic (3.48e-3)" "unprognostic (2.26e-3)" "unprognostic (9.84e-2)" "prognostic unfavorable (1.22e-5)" "unprognostic (2.09e-2)" 38.7 63.1 25.7 20.3 24.1 0.2 32.7 26.6 16.1 77.8 70.2 32.7 12.9 81.4 25.2 33.9 44.1 114.6 39.9 27.9 69.2 11.0 8.2 44.8 12.1 42.5 49.5 107.2 6.7 35.4 14.6 78.8 45.6 47.9 21.4 9.5 28.6 55.4 11.3 39.3 20.2 62.1 36.5 28.3 14.5 11.7 38.3 10.5 43.3 24.0 13.0 52.3 42.4 36.6 36.8 39.5 36.4 33.9 162.7 78.8 0.6 57.1 115.6 63.2 51.5 0.4 3.0 0.0 31.6 147.4 41.7 31.7 30.7 33.8 59.9 0.1 24.4 9.5 90.5 11.9 71.1 7.6 5.1 129.7 13.4 55.5 36.4 140.9 17.3 19.4 6.7 0.1 367.9 15.2 22.1 0.5 35.8 0.0 26.5 0.1 186.3 0.6 13.8 27.9 21.1 91.0 104.3 0.5 37.5 23.7 11.0 2.3 240.4 71.3 61.6 72.1 59.6 0.2 0.1 0.2 37.3 6.7 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 25.7 24.1 26.6 16.1 27.9 69.2 42.5 49.5 45.6 36.5 38.3 36.6 4.7 6.4 20.0 130.6 0.0 49.5 21.1 15.4 17.6 1.7 7.9 13.8 6.8 0.0 8.3 0.0 0.0 0.7 0.1 0.0 0.0 1.5 37.9 5.5 78.1 4.3 0.0 0.0 61.9 2.6 1.9 68.2 0.0 11.7 1.3 22.1 3.3 0.1 4.0 0.0 64.3 0.0 4.1 0.8 19.8 33.9 42.6 2.9 24.9 40.3 0.6 13.6 0.0 141.8 1.3 1.1 0.0 67.7 1.2 10.1 0.0 0.1 9.9 0.8 19.7 111.7 59.6 5.2 2.7 4.6 23.4 1.4 1.7 26.4 0.0 8.9 AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512941-36724549 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.3;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 77.9;Kupffer cells: 119.7;Macrophages: 77.1;Microglial cells: 233.3;monocytes: 67.5;NK-cells: 90.6;T-cells: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 298.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "GAMG: 4.8;NB-4: 26.5;THP-1: 20.2;U-937: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA021666, HPA026716" Approved Uncertain Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA021666: AB_2670799, HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" 7.5 5.1 2.4 33.7 2.2 43.3 3.8 2.1 3.1 5.7 4.7 10.4 9.5 2.8 1.5 3.3 3.5 15.6 2.0 2.1 3.6 1.9 13.2 12.7 35.1 6.6 5.1 2.6 1.5 1.5 0.9 11.2 5.7 2.5 13.3 0.8 3.7 2.8 0.5 0.8 12.1 9.3 4.0 64.9 7.0 1.3 5.1 13.9 1.8 0.9 15.1 13.9 1.3 8.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.6 26.5 0.1 0.0 0.0 0.5 0.0 0.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 8.9 0.0 1.8 298.5 97.8 43.6 251.9 9.0 2.6 2.2 30.7 183.1 0.3 4.8 37.3 97.9 106.8 113.2 2.7 0.7 207.3 2.4 2.2 2.1 3.1 2.1 3.6 6.6 5.1 5.7 4.0 5.1 8.6 1.3 0.0 9.6 1.3 3.6 0.8 0.1 0.0 0.0 1.1 0.6 1.7 0.5 1.5 2.5 0.0 0.0 0.2 77.9 9.2 1.9 0.3 0.6 0.4 0.3 1.4 15.5 16.0 12.4 0.0 0.2 3.1 2.6 0.4 5.1 0.7 2.5 0.9 32.8 0.0 8.1 0.3 0.0 119.7 20.3 1.2 0.0 77.1 0.0 233.3 67.5 2.8 90.6 12.1 38.6 0.0 3.8 0.4 13.6 0.1 0.3 0.5 0.7 0.3 0.0 0.3 0.5 0.0 0.1 0.4 0.3 0.1 54.1 0.6 0.9 0.2 AP1M2 "AP1-mu2, HSMU1B, mu2" ENSG00000129354 "Adaptor related protein complex 1 subunit mu 2" Q9Y6Q5 19 10572671-10587315 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 162.0;Proximal tubular cells: 373.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.3;neutrophil: 7.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.6" "Cell line enhanced" "Detected in many" "CACO-2: 172.8;Hep G2: 313.8;MCF7: 268.3;OE19: 156.7;RT4: 164.9;U-2 OS: 166.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA054999 Supported Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA054999: AB_2682666" "unprognostic (8.31e-2)" "unprognostic (2.38e-1)" "unprognostic (1.87e-1)" "prognostic favorable (2.07e-4)" "unprognostic (2.07e-1)" "unprognostic (7.76e-2)" "unprognostic (2.11e-3)" "unprognostic (4.83e-2)" "unprognostic (1.93e-1)" "unprognostic (2.49e-2)" "unprognostic (2.65e-1)" "unprognostic (2.23e-2)" "prognostic favorable (3.73e-6)" "unprognostic (1.80e-2)" "unprognostic (8.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.06e-1)" 3.4 0.1 0.8 6.4 0.3 0.9 32.9 0.6 0.8 27.1 0.3 67.1 64.0 6.6 61.8 51.9 46.6 22.7 0.4 0.5 0.4 76.3 1.5 19.2 0.4 0.7 0.6 0.3 55.9 62.4 34.8 16.2 0.4 30.8 63.4 0.1 41.5 24.0 0.3 42.1 54.8 3.0 0.3 0.6 59.1 9.6 0.7 4.2 58.8 0.3 9.5 23.4 19.1 0.6 144.2 71.1 0.4 10.4 0.0 0.0 65.0 0.2 0.0 2.3 1.6 172.8 82.1 0.4 64.7 1.2 43.4 97.6 0.1 109.0 3.2 0.6 1.0 6.7 48.5 313.8 1.3 0.3 0.8 0.2 81.6 3.9 0.1 5.0 0.0 0.4 0.3 0.6 1.2 268.3 0.6 1.8 31.4 156.7 0.0 2.4 9.3 0.7 2.7 164.9 67.3 0.2 0.0 120.0 0.6 34.6 123.3 0.4 0.0 0.4 166.7 0.9 2.2 0.4 0.9 1.4 0.2 0.4 0.2 4.3 0.4 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 7.6 0.0 1.4 0.2 0.0 2.7 0.8 0.3 0.6 0.8 0.5 0.4 0.7 0.6 0.4 0.3 0.7 0.6 0.4 28.9 34.8 0.0 1.9 6.9 19.2 68.9 13.1 0.0 49.3 30.0 0.5 47.1 64.2 86.5 0.0 123.0 0.5 112.2 137.0 141.3 43.4 52.4 5.4 1.7 74.4 0.0 0.3 115.8 101.0 1.5 73.4 57.7 2.5 0.0 0.7 0.0 9.8 0.0 0.2 95.5 97.6 0.8 0.0 19.9 1.5 2.6 3.6 0.0 1.7 0.0 0.0 0.0 0.2 130.2 125.6 0.7 0.0 37.6 162.0 373.6 61.5 0.0 0.0 0.0 6.2 16.9 4.1 39.1 13.1 66.1 2.8 0.0 131.4 48.3 AP1S3 ENSG00000152056 "Adaptor related protein complex 1 subunit sigma 3" Q96PC3 2 223751686-223838027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 52.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Cytotrophoblasts: 48.2;Pancreatic endocrine cells: 44.2;Urothelial cells: 69.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.9;dendritic cells: 4.0;granulocytes: 4.9" "Cell line enhanced" "Detected in many" "CACO-2: 151.1;RPTEC TERT1: 56.8;RT4: 52.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066782 Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA066782: AB_2685720" "unprognostic (9.45e-3)" "unprognostic (1.79e-1)" "unprognostic (7.52e-2)" "unprognostic (5.80e-2)" "unprognostic (4.37e-2)" "unprognostic (4.89e-1)" "unprognostic (1.65e-3)" "prognostic unfavorable (3.36e-5)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.08e-5)" "unprognostic (1.56e-1)" "unprognostic (2.33e-1)" "unprognostic (2.50e-2)" "unprognostic (1.90e-1)" "unprognostic (2.32e-2)" "unprognostic (4.61e-2)" 0.7 0.8 3.4 3.3 3.2 4.0 2.1 3.9 3.5 2.2 0.5 2.7 5.3 0.9 52.8 4.8 2.3 5.2 0.5 2.8 3.0 5.6 1.4 4.7 4.2 2.0 1.6 0.5 2.4 3.8 1.1 6.6 1.5 2.9 2.6 5.7 1.6 5.4 0.9 1.9 5.0 0.7 1.1 2.8 9.8 0.9 3.2 1.6 14.4 0.3 5.2 8.1 1.2 2.1 28.7 17.7 2.4 12.0 1.5 0.6 13.5 11.5 2.4 4.9 4.2 151.1 21.8 11.0 8.0 1.7 5.8 43.8 6.4 30.3 6.8 15.3 8.9 1.2 33.7 15.7 0.6 3.4 1.3 0.6 31.2 9.1 30.1 11.2 3.4 5.8 1.8 2.9 2.9 12.3 0.6 0.9 3.8 32.8 15.5 4.3 0.1 4.5 56.8 52.1 7.4 2.1 5.4 11.8 3.8 6.1 5.0 6.3 2.0 1.6 4.6 3.1 9.2 10.2 9.0 28.2 4.4 2.0 6.0 4.9 0.5 0.3 0.6 0.4 0.5 4.9 0.4 0.4 1.2 2.7 0.4 0.5 1.8 0.6 0.2 4.0 1.0 0.4 3.4 3.2 3.9 3.5 2.8 3.0 2.0 1.6 1.5 1.1 3.2 2.1 0.4 35.3 6.7 8.8 24.2 4.2 32.6 15.3 4.0 3.3 4.3 1.8 1.7 0.0 15.8 11.0 64.6 48.2 13.6 3.6 9.8 17.5 0.2 8.1 2.1 2.1 2.4 0.0 19.3 18.1 3.4 3.5 11.7 26.1 3.8 0.8 0.7 0.4 4.7 6.7 9.6 3.6 16.2 1.6 38.1 0.0 0.3 7.5 3.6 4.7 7.4 1.9 6.2 10.6 4.0 44.2 4.6 0.0 10.7 26.6 5.4 4.5 10.3 5.9 0.0 1.1 1.8 0.3 1.9 6.3 4.1 13.1 6.9 1.0 4.7 69.6 AP2A1 "ADTAA, CLAPA1" ENSG00000196961 "Adaptor related protein complex 2 subunit alpha 1" O95782 19 49767001-49807114 "Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 165.0;Syncytiotrophoblasts: 241.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 20.5" "Lineage enriched" "Detected in all" 4 "monocytes: 20.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB004306 Approved Supported Vesicles NA NA 61000 "Cluster 51: Monocytes - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "CAB004306: AB_2274034" "unprognostic (4.33e-2)" "unprognostic (1.52e-1)" "unprognostic (4.61e-1)" "unprognostic (7.18e-2)" "unprognostic (1.88e-1)" "unprognostic (1.23e-1)" "unprognostic (1.92e-2)" "unprognostic (5.85e-3)" "unprognostic (4.84e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (2.82e-2)" "unprognostic (2.38e-2)" "prognostic unfavorable (2.83e-9)" "unprognostic (2.63e-1)" "unprognostic (1.45e-1)" "unprognostic (7.90e-2)" "unprognostic (1.72e-3)" 47.0 87.4 37.4 25.2 47.9 54.4 41.2 20.6 49.2 48.1 9.0 42.2 24.7 56.6 7.4 46.5 48.2 19.6 52.2 44.2 31.8 33.3 51.1 37.2 19.5 45.8 31.4 57.1 33.8 13.9 34.3 31.4 45.3 33.0 9.9 13.9 28.9 18.6 89.6 54.2 34.0 21.4 17.8 47.6 36.3 88.8 50.0 15.4 30.5 26.9 13.2 46.0 43.6 35.8 70.9 100.3 33.8 78.7 59.5 72.2 69.0 82.0 55.3 49.7 51.8 52.0 43.5 31.5 30.6 85.2 41.9 62.8 25.7 59.0 21.1 50.1 58.4 46.6 66.1 56.8 65.3 37.7 75.0 113.6 42.3 55.4 28.7 44.2 59.5 51.3 118.5 42.7 47.6 55.8 41.6 50.2 34.6 66.6 101.8 46.6 79.7 40.4 29.6 88.1 25.7 34.7 90.1 61.1 34.3 36.1 52.1 52.9 82.9 128.4 70.6 54.6 59.3 63.1 83.5 33.1 90.5 54.8 55.1 0.3 5.3 3.4 2.0 12.8 1.4 1.2 1.2 1.2 4.6 1.0 0.9 1.3 4.0 2.3 20.5 1.4 1.6 4.8 37.4 47.9 20.6 49.2 44.2 31.8 45.8 31.4 45.3 17.8 50.0 35.8 22.9 0.0 2.3 19.6 18.5 13.8 19.0 18.5 14.8 45.1 26.7 19.0 2.9 14.3 11.7 14.7 43.8 90.8 21.8 39.1 11.7 16.1 129.9 23.0 57.1 22.4 2.4 106.5 24.2 29.4 35.3 36.0 22.4 16.0 8.9 33.2 39.3 36.6 31.3 50.5 25.5 17.4 8.2 56.2 21.3 165.0 53.4 34.0 19.6 14.0 40.4 31.5 63.8 14.1 21.8 27.3 19.0 61.7 28.1 16.3 41.2 50.4 14.9 30.2 59.2 23.2 28.5 54.7 59.2 22.1 13.9 241.6 23.2 48.6 23.9 24.3 AP2B1 "ADTB2, CLAPB1" ENSG00000006125 "Adaptor related protein complex 2 subunit beta 1" P63010 17 35578046-35726413 "Cancer-related genes, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 503.9;Late spermatids: 739.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017631, HPA056733, HPA067983" Approved Supported Vesicles NA NA 380000 "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB017631: AB_2058201, HPA056733: AB_2683219, HPA067983: AB_2732777" "unprognostic (1.49e-2)" "unprognostic (4.04e-3)" "unprognostic (2.15e-3)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-2)" "unprognostic (1.51e-3)" "unprognostic (2.64e-2)" "unprognostic (1.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.58e-2)" "unprognostic (2.50e-1)" "prognostic favorable (2.62e-4)" "unprognostic (1.70e-1)" "unprognostic (1.10e-1)" "unprognostic (3.25e-2)" "unprognostic (1.57e-2)" 46.4 42.4 77.0 38.2 87.8 49.2 58.3 69.9 88.7 54.1 76.6 67.6 33.5 41.7 70.7 25.1 46.7 42.3 67.6 92.1 83.5 69.0 35.0 53.4 38.6 69.8 78.6 57.2 33.2 126.4 55.0 66.8 76.8 40.9 84.0 76.1 41.9 50.1 57.5 29.9 38.8 56.0 80.3 42.0 48.4 93.5 78.7 59.7 65.1 61.0 45.5 46.8 34.4 95.0 188.8 233.9 113.7 132.0 184.4 202.8 51.6 94.3 138.9 131.0 141.1 129.0 154.6 90.5 81.1 175.3 168.8 173.2 162.5 264.8 190.8 108.6 147.0 117.7 161.8 71.0 104.7 119.3 80.8 128.9 104.3 134.5 209.3 151.2 211.4 111.8 190.6 126.9 206.9 36.9 113.7 58.7 94.2 98.9 164.5 94.3 165.1 64.7 166.2 108.3 94.4 114.1 114.5 39.6 126.9 273.3 161.5 78.5 211.5 99.3 93.4 109.8 142.1 53.0 106.1 84.7 124.1 86.9 112.5 19.6 11.8 16.7 16.0 15.3 16.9 12.1 13.9 14.3 10.7 11.9 6.3 8.0 13.3 9.6 16.8 10.7 20.5 11.0 77.0 87.8 69.9 88.7 92.1 83.5 69.8 78.6 76.8 80.3 78.7 95.0 76.5 16.0 17.0 49.3 45.9 31.1 26.3 57.4 70.6 67.6 88.9 50.9 62.5 68.6 37.4 112.2 56.3 29.7 70.7 97.4 117.4 105.0 503.9 74.5 83.7 56.8 71.3 214.7 105.5 120.2 42.8 47.1 36.2 85.4 41.2 46.5 79.9 64.5 44.1 69.0 109.8 79.4 28.5 54.3 25.9 739.2 58.7 37.2 16.0 60.0 47.3 52.6 74.2 81.4 89.0 177.9 46.6 68.4 32.1 37.4 39.4 102.5 30.4 40.9 59.2 25.3 37.6 258.8 60.0 19.6 14.6 32.8 49.2 37.3 89.8 29.1 AP3S1 CLAPS3 ENSG00000177879 "Adaptor related protein complex 3 subunit sigma 1" Q92572 5 115841592-115914081 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049270 Uncertain Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA049270: AB_2680696" "prognostic unfavorable (1.22e-4)" "unprognostic (2.54e-2)" "unprognostic (8.05e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (3.33e-4)" "unprognostic (2.60e-2)" "unprognostic (3.83e-3)" "unprognostic (4.42e-3)" "unprognostic (1.36e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.13e-5)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.57e-8)" "unprognostic (2.73e-2)" "unprognostic (3.62e-2)" "unprognostic (2.75e-1)" "unprognostic (1.64e-1)" 63.1 44.5 57.0 38.7 59.7 133.3 60.1 55.2 84.5 70.1 54.6 53.7 61.9 55.1 113.6 65.8 46.1 49.2 52.6 61.5 60.7 37.4 74.7 38.1 64.6 62.3 60.3 69.6 63.2 24.9 19.7 60.1 62.8 43.6 60.1 34.0 59.4 85.6 21.9 60.7 81.5 64.1 59.1 39.0 37.7 57.3 58.4 41.1 49.3 34.4 61.1 60.2 25.4 59.5 134.3 44.8 95.2 63.4 257.4 369.1 89.2 142.6 132.4 94.1 152.0 98.9 121.4 107.5 68.4 162.8 115.4 38.1 58.8 230.4 157.6 320.3 114.4 45.1 43.8 146.2 139.8 76.2 84.6 168.6 177.9 100.2 112.1 123.5 109.4 122.1 47.1 80.9 150.3 49.9 87.3 129.0 71.1 65.5 74.4 85.0 141.9 172.0 123.2 58.8 35.1 53.8 222.8 42.7 146.3 86.2 70.3 116.1 115.4 173.1 116.5 127.1 113.4 71.6 47.3 91.8 129.9 144.2 73.5 81.9 70.7 174.8 37.6 79.2 63.7 67.1 47.1 52.3 54.5 47.3 39.9 41.6 110.0 48.3 75.8 94.8 60.3 70.6 57.0 59.7 55.2 84.5 61.5 60.7 62.3 60.3 62.8 59.1 58.4 59.5 75.6 22.4 21.9 31.3 90.1 203.0 92.8 308.5 95.0 68.0 72.9 59.3 26.4 67.2 115.0 46.0 25.0 74.1 95.0 129.7 70.5 93.6 130.2 37.8 62.1 73.9 76.1 31.7 83.1 86.5 309.4 158.3 43.8 35.1 83.6 39.6 81.8 87.2 152.6 26.9 61.2 131.5 105.8 111.7 185.7 217.4 173.1 88.4 115.6 68.4 103.9 19.6 74.2 46.3 49.9 111.4 105.5 111.3 103.6 118.3 361.1 156.7 59.8 77.7 32.9 48.2 118.0 108.8 104.7 131.5 227.9 128.7 79.0 60.7 74.9 112.5 AP3S2 sigma3b ENSG00000157823 "Adaptor related protein complex 3 subunit sigma 2" P59780 15 89830599-89894638 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049270 Uncertain Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA049270: AB_2680696" "unprognostic (1.46e-1)" "unprognostic (1.60e-2)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "unprognostic (2.68e-1)" "unprognostic (3.78e-2)" "unprognostic (5.27e-2)" "unprognostic (3.03e-1)" "unprognostic (7.59e-2)" "unprognostic (1.22e-1)" "unprognostic (4.31e-2)" "prognostic favorable (5.55e-16)" "unprognostic (7.97e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (8.67e-3)" 24.2 20.3 15.1 11.2 15.8 10.4 19.4 14.9 18.1 17.3 13.3 19.3 10.9 13.0 16.3 20.7 17.3 17.5 30.7 15.0 17.0 36.5 40.5 16.3 12.9 16.0 18.4 20.0 19.0 32.6 9.0 18.5 18.4 15.3 19.2 44.0 13.5 21.4 44.8 8.7 10.2 18.0 15.0 12.6 10.0 12.5 16.7 20.1 26.2 45.2 17.7 15.3 6.8 16.7 13.5 60.6 33.4 35.6 66.7 45.6 28.0 58.8 75.2 74.3 59.7 26.0 34.8 12.1 51.3 39.1 48.9 31.0 57.4 33.1 58.3 51.2 29.0 37.3 25.4 33.6 28.1 16.1 22.3 30.9 40.4 20.7 41.6 40.6 38.8 30.8 29.1 32.8 48.0 27.7 27.6 8.7 37.2 68.5 11.6 15.9 33.8 25.0 42.1 35.9 25.5 22.3 69.4 43.1 40.4 69.8 26.9 14.1 16.3 40.0 19.2 62.1 19.6 28.3 94.5 28.9 35.8 18.7 24.1 6.3 16.6 7.8 5.0 15.4 7.8 4.5 7.2 7.4 11.6 6.3 5.7 4.0 16.1 8.3 19.9 7.4 8.4 10.6 15.1 15.8 14.9 18.1 15.0 17.0 16.0 18.4 18.4 15.0 16.7 16.7 5.9 12.8 15.4 0.0 5.9 3.3 4.0 6.0 5.2 22.0 8.0 5.7 18.2 10.0 11.2 5.5 35.5 8.9 6.1 34.4 9.8 13.4 3.1 5.9 10.8 7.2 14.4 5.0 0.0 16.1 4.2 9.0 8.2 7.1 8.2 15.4 8.9 17.0 6.4 18.5 0.0 11.4 2.0 12.0 6.4 3.2 7.2 9.7 8.8 0.0 16.9 17.3 9.2 0.0 0.0 13.4 16.4 7.5 8.6 5.8 15.8 13.7 9.8 30.6 0.0 6.1 6.0 11.6 8.3 6.1 2.8 6.4 6.2 28.5 15.2 4.2 AP4B1 "BETA-4, SPG47" ENSG00000134262 "Adaptor related protein complex 4 subunit beta 1" Q9Y6B7 1 113894194-113905201 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 65.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028162, HPA028652" Approved Approved Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Vesicles "HPA028162: AB_10610976, HPA028652: AB_10601451" "unprognostic (8.90e-2)" "unprognostic (2.25e-2)" "unprognostic (1.77e-1)" "unprognostic (2.40e-2)" "unprognostic (1.53e-1)" "unprognostic (5.01e-2)" "prognostic unfavorable (8.60e-7)" "unprognostic (3.45e-2)" "unprognostic (1.54e-2)" "unprognostic (8.34e-3)" "unprognostic (1.55e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (3.73e-6)" "unprognostic (5.08e-3)" "unprognostic (7.88e-2)" "unprognostic (3.12e-1)" "unprognostic (1.55e-2)" 9.7 8.5 12.5 11.1 13.1 20.5 9.3 14.6 14.6 11.9 10.9 11.5 10.6 9.7 14.2 12.1 11.0 7.0 11.2 13.0 13.0 9.7 8.4 9.5 14.3 11.6 11.4 13.7 14.0 4.8 13.7 5.9 11.8 9.6 12.7 20.0 7.6 6.2 11.7 11.5 12.8 9.1 11.5 20.1 10.4 11.1 13.3 16.1 11.0 9.1 13.9 9.2 10.0 13.3 11.0 9.8 10.0 11.8 15.7 14.1 6.4 10.1 9.8 13.0 14.0 6.8 7.7 21.5 15.9 12.4 6.5 9.7 11.3 13.4 16.5 16.6 9.8 17.6 13.6 8.3 9.5 19.6 17.3 16.1 6.7 25.5 15.3 7.8 22.7 20.9 12.3 18.5 17.6 65.2 15.6 21.6 9.4 7.7 19.0 15.0 19.5 13.3 13.2 5.5 10.2 8.5 10.1 19.1 7.8 9.5 5.7 15.4 21.8 15.0 13.9 17.4 20.8 15.2 15.8 21.3 24.6 26.0 25.1 15.9 10.5 8.6 14.7 10.8 15.6 9.5 11.7 12.6 12.9 11.9 12.7 11.1 1.2 12.2 8.5 9.1 10.4 9.5 12.5 13.1 14.6 14.6 13.0 13.0 11.6 11.4 11.8 11.5 13.3 13.3 7.2 3.2 6.7 7.5 12.3 3.6 3.3 5.4 4.6 6.8 3.2 4.3 8.7 5.7 11.9 3.7 31.3 3.8 12.0 7.8 1.9 7.7 3.6 4.6 4.7 7.6 3.0 18.1 11.4 26.8 3.5 7.0 11.2 5.2 2.5 4.5 7.5 4.1 5.2 8.4 11.6 5.3 6.1 7.3 4.9 2.3 2.8 6.9 7.2 7.5 6.1 4.7 3.1 11.6 10.0 10.9 6.9 4.9 7.4 2.8 6.5 3.3 5.2 21.0 13.1 6.1 6.2 16.4 11.5 5.7 3.7 1.6 14.8 6.4 9.0 3.3 AP4S1 "AP47B, CLA20, SPG52" ENSG00000100478 "Adaptor related protein complex 4 subunit sigma 1" Q9Y587 14 31025106-31130996 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039963 Approved Supported Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA039963: AB_10795240" "unprognostic (4.03e-2)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (2.43e-1)" "unprognostic (1.14e-1)" "unprognostic (8.00e-3)" "unprognostic (1.03e-1)" "prognostic favorable (7.44e-4)" "unprognostic (3.79e-2)" "unprognostic (8.62e-3)" "unprognostic (1.15e-2)" "unprognostic (3.02e-1)" "prognostic favorable (2.87e-6)" "unprognostic (2.20e-3)" "unprognostic (5.44e-2)" "unprognostic (7.75e-2)" "unprognostic (5.59e-2)" 4.8 6.3 9.8 6.6 10.6 6.0 5.7 14.1 12.8 6.5 5.6 8.6 3.9 7.7 7.0 4.9 7.3 5.4 8.7 9.5 10.2 7.8 6.2 5.4 8.1 6.3 6.5 10.7 7.9 6.5 8.5 6.7 6.1 6.2 4.1 11.9 5.2 6.7 12.6 4.6 4.4 7.9 5.4 8.0 4.3 18.4 9.0 6.6 8.8 7.2 7.7 6.2 4.8 10.1 9.0 12.6 11.0 3.2 4.4 7.9 8.5 6.0 10.4 9.6 9.5 12.2 14.5 10.6 5.5 7.3 7.2 9.7 7.6 9.4 15.9 9.1 4.4 16.4 5.5 19.0 9.5 14.1 9.2 6.3 5.9 9.6 12.0 6.4 11.7 8.0 8.4 7.0 10.3 12.5 9.7 7.8 13.1 10.5 10.9 10.3 9.8 1.4 10.5 12.4 6.1 6.1 10.7 5.1 16.3 7.3 10.8 6.5 8.8 7.3 6.5 5.0 5.2 8.6 17.0 15.9 4.2 4.4 5.7 3.4 1.3 2.4 2.5 3.5 3.7 3.3 3.8 3.0 1.2 3.4 3.7 4.5 2.6 5.8 2.8 3.3 6.6 1.7 9.8 10.6 14.1 12.8 9.5 10.2 6.3 6.5 6.1 5.4 9.0 10.1 7.1 9.6 7.7 10.7 8.1 3.4 6.5 6.5 1.2 12.1 4.0 4.3 16.5 4.3 3.1 5.5 31.3 9.1 7.6 3.9 5.9 7.6 21.9 5.2 8.8 6.7 6.0 3.8 29.4 4.8 5.3 6.2 7.1 5.8 7.6 7.8 10.8 4.0 7.4 6.7 24.9 3.8 4.1 5.4 4.1 17.0 6.8 6.0 3.6 12.2 7.5 9.3 5.2 25.1 16.4 2.8 6.2 8.6 4.2 4.0 5.0 7.7 8.1 24.4 6.6 8.5 8.1 36.0 8.3 3.0 2.8 11.5 7.3 8.2 4.0 5.2 APBA3 "mint3, X11L2" ENSG00000011132 "Amyloid beta precursor protein binding family A member 3" O96018 19 3750772-3761692 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045577 Approved Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA045577: AB_10964881" "unprognostic (3.47e-2)" "unprognostic (3.58e-2)" "unprognostic (5.00e-2)" "prognostic favorable (5.97e-4)" "unprognostic (1.69e-1)" "prognostic favorable (4.91e-4)" "unprognostic (6.64e-2)" "unprognostic (7.60e-3)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "prognostic favorable (1.51e-4)" "unprognostic (5.58e-3)" "unprognostic (2.67e-3)" "unprognostic (1.31e-2)" "unprognostic (2.28e-1)" "unprognostic (6.12e-2)" "prognostic favorable (1.83e-4)" 6.7 6.7 3.1 3.5 4.0 2.0 7.1 3.8 5.3 8.0 2.8 8.0 3.5 7.9 0.1 7.5 6.9 1.1 7.6 2.9 3.2 8.3 10.3 6.7 3.7 4.4 3.7 9.4 7.9 1.5 7.1 2.0 4.1 7.5 0.6 0.4 8.4 2.5 15.4 7.5 8.4 1.4 3.4 11.2 8.3 3.2 3.7 2.8 8.3 2.7 1.9 7.5 6.8 5.6 8.0 6.0 1.3 2.3 2.4 1.8 6.4 5.1 3.0 2.7 3.7 5.8 2.7 5.4 4.4 2.0 6.3 3.8 1.4 4.3 0.6 20.5 4.5 3.1 4.9 4.6 8.1 1.9 11.2 3.6 5.3 3.4 2.2 2.2 3.7 5.5 5.2 8.4 1.2 4.7 6.1 7.8 3.5 2.6 8.9 6.3 2.6 8.9 1.9 5.0 4.6 4.8 3.2 4.6 7.9 0.8 2.0 4.6 6.4 4.5 4.6 7.9 6.3 17.0 6.8 4.9 4.1 6.2 4.8 11.3 7.3 11.4 13.0 5.6 11.9 9.5 12.9 12.9 8.3 11.6 8.2 10.0 10.2 6.9 5.1 7.8 19.8 8.4 3.1 4.0 3.8 5.3 2.9 3.2 4.4 3.7 4.1 3.4 3.7 5.6 4.9 6.4 5.6 2.9 12.1 4.2 6.5 18.1 4.0 3.9 7.0 6.2 4.7 4.3 7.9 7.3 8.4 10.6 9.0 8.0 7.9 14.2 0.9 2.9 4.8 6.4 4.8 1.3 3.4 9.0 10.0 7.6 13.3 5.4 2.5 5.4 5.3 8.2 8.6 3.3 3.2 9.1 10.2 6.7 9.3 0.5 6.2 5.9 5.4 1.0 16.4 3.3 13.4 3.0 5.2 12.6 5.8 3.0 13.4 9.3 19.5 11.3 3.8 6.4 6.6 4.0 5.1 2.5 6.2 7.7 7.5 15.3 12.4 3.5 7.5 6.4 APLP2 "APPH, APPL2" ENSG00000084234 "Amyloid beta precursor like protein 2" Q06481 11 130068147-130144811 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 249.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039319 Approved Approved Vesicles NA NA 1500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA039319: AB_10673141" "unprognostic (2.83e-2)" "unprognostic (1.29e-1)" "unprognostic (2.06e-1)" "unprognostic (3.18e-2)" "unprognostic (1.24e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (3.37e-4)" "unprognostic (3.86e-2)" "unprognostic (2.33e-1)" "unprognostic (2.70e-2)" "unprognostic (3.12e-3)" "unprognostic (7.44e-2)" "prognostic favorable (1.33e-9)" "unprognostic (3.20e-3)" "unprognostic (4.95e-2)" "prognostic favorable (2.90e-4)" "unprognostic (4.42e-2)" 217.2 130.2 125.6 144.0 126.0 196.5 192.3 164.7 157.9 170.4 252.6 209.9 272.4 176.6 138.6 134.2 167.6 201.8 271.6 131.0 153.2 359.9 334.8 391.4 77.5 130.9 137.5 180.8 136.0 291.5 87.1 324.8 133.1 287.7 176.7 540.8 135.3 291.0 65.9 113.3 226.6 211.5 135.4 95.7 149.7 54.9 157.9 81.5 607.8 85.2 56.8 199.1 129.6 152.8 216.7 170.3 307.1 281.2 1259.7 847.8 393.7 598.6 741.1 294.2 251.8 1300.5 1541.3 107.9 1515.3 1422.2 322.4 540.4 229.1 567.6 168.0 165.6 206.4 180.9 116.7 502.9 191.9 556.7 363.8 566.4 367.8 244.5 469.5 1520.2 912.7 34.1 180.7 228.9 495.2 205.7 26.9 245.3 182.8 256.8 301.1 70.0 69.8 105.5 758.9 589.6 109.9 239.0 706.9 368.0 92.0 535.8 582.2 489.5 1567.6 314.1 211.7 496.8 281.9 33.8 50.6 245.5 347.0 487.7 221.0 55.1 249.3 65.3 17.9 122.2 13.5 16.3 12.7 17.0 110.1 44.8 9.4 12.6 160.8 15.6 94.6 10.5 20.0 149.5 125.6 126.0 164.7 157.9 131.0 153.2 130.9 137.5 133.1 135.4 157.9 152.8 239.6 942.3 550.3 37.9 74.4 106.7 175.4 497.0 78.6 967.9 252.9 183.1 262.0 254.5 460.6 404.6 706.8 798.1 72.0 354.2 52.8 305.5 13.6 211.0 191.3 220.3 92.8 156.3 99.0 107.1 130.3 253.5 86.6 432.8 103.5 109.6 127.1 498.2 652.4 240.6 133.5 159.8 463.9 287.6 214.3 13.8 167.4 405.5 96.0 54.4 293.1 396.1 56.7 45.8 31.6 276.5 220.7 214.4 45.5 190.1 352.0 244.9 258.3 729.0 190.7 148.9 207.7 182.8 240.4 81.6 109.4 927.3 58.8 165.9 161.5 215.4 APOA4 ENSG00000110244 "Apolipoprotein A4" P06727 11 116820700-116823304 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "intestine: 3112.4" "Cell type enriched" "Detected in some" 44 "Proximal enterocytes: 10311.5" "Cancer enriched" "Detected in some" 29 "liver cancer: 291.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.7;CACO-2: 8.0;Hep G2: 7.7;NB-4: 7.3;RPMI-8226: 12.5;SH-SY5Y: 10.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001352, HPA002549, CAB068250, CAB068251, CAB068252" Enhanced Approved Vesicles "Secreted to blood" NA NA 61200000000 74000000000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB068250: AB_2665657, CAB068251: AB_2665659, CAB068252: AB_2665658, HPA001352: AB_1078179, HPA002549: AB_1078177" "unprognostic (8.81e-2)" "unprognostic (2.12e-2)" "unprognostic (1.75e-2)" "unprognostic (7.91e-2)" 0.3 0.0 0.0 2.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.9 2204.9 1.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 257.2 0.0 2.4 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 3112.4 3.0 0.0 0.1 4.6 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 3.1 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 77.5 0.0 0.0 0.0 234.3 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 221.5 0.0 0.0 0.0 10311.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 87.7 0.0 APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 9363.4;Hofbauer cells: 6072.6;Muller glia cells: 9454.8;Peritubular cells: 4958.2;Proximal tubular cells: 8155.9;Theca cells: 7201.0" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1867.0;CACO-2: 466.1;Hep G2: 935.3;HSkMC: 1374.2;SK-MEL-30: 1956.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" 522.1 3453.9 813.4 92.8 1164.2 66.5 325.1 775.0 943.2 271.2 329.2 130.9 40.3 81.5 20.0 37.2 72.2 100.2 176.3 606.1 841.6 1066.0 6592.5 258.8 352.2 1016.0 1037.0 508.2 41.9 34.5 110.9 102.2 1106.9 45.4 22.9 87.6 80.5 10.8 31.1 381.2 165.9 12.6 823.2 620.3 83.3 140.5 962.6 57.8 146.4 10.4 46.1 93.4 135.5 964.4 3.2 5.2 9.5 2.6 1867.0 76.3 69.4 1.5 4.3 8.4 1.4 466.1 2.8 2.0 9.9 0.3 9.1 6.4 12.6 2.1 0.7 1.7 4.0 3.3 1.7 935.3 192.4 6.8 2.3 1374.2 2.5 14.8 1.3 15.6 1.0 0.7 124.9 2.8 1.2 3.3 1.9 2.5 243.2 3.0 1.3 2.6 8.0 1.8 2.8 0.9 5.6 2.4 4.5 1.4 1956.0 131.6 165.3 52.8 3.3 13.2 3.1 1.4 1.6 5.9 8.6 3.8 5.9 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 813.4 1164.2 775.0 943.2 606.1 841.6 1016.0 1037.0 1106.9 823.2 962.6 964.4 136.7 0.0 8.2 444.0 66.1 935.2 12.3 18.3 67.7 81.7 86.7 565.8 2.2 450.4 5.2 228.1 41.7 46.3 6.0 2.2 682.9 1.8 73.6 33.8 936.6 140.2 0.0 331.6 1.1 0.7 43.8 860.7 3.6 22.9 174.4 103.6 208.9 9363.4 6072.6 38.7 2.1 0.6 4.1 718.0 292.6 355.3 2629.4 940.6 2481.3 60.9 70.3 9454.8 0.0 12.1 2.2 0.6 0.3 4958.2 7.2 15.0 0.2 8155.9 1.0 311.4 223.5 2958.4 345.5 14.8 12.8 15.1 1684.9 74.3 60.6 7201.0 1.7 4.7 APOL4 APOLIV ENSG00000100336 "Apolipoprotein L4" Q9BPW4 22 36189124-36204840 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 32.7;Enteroendocrine cells: 14.9;Glandular and luminal cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.6;myeloid DC: 1.5" "Group enriched" "Detected in many" 4 "dendritic cells: 1.5;monocytes: 1.6" "Cell line enhanced" "Detected in some" "BEWO: 18.7;HDLM-2: 109.9;HSkMC: 16.1;K-562: 23.7;SCLC-21H: 47.9" "HPA049797, HPA055435" Uncertain Supported Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Vesicles "HPA049797: AB_2680887, HPA055435: AB_2682816" "unprognostic (2.73e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.51e-1)" "unprognostic (5.31e-1)" "unprognostic (3.39e-2)" "unprognostic (2.44e-2)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "prognostic favorable (3.45e-4)" "unprognostic (1.33e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (2.00e-5)" "unprognostic (4.26e-2)" "unprognostic (3.69e-1)" "unprognostic (4.18e-2)" "prognostic favorable (2.40e-6)" 13.5 1.0 0.8 6.0 0.8 1.5 14.7 0.9 2.2 4.6 0.5 3.3 4.8 3.9 1.6 4.3 5.9 6.3 5.3 0.9 1.6 8.1 2.0 12.8 4.7 2.5 1.3 3.9 1.0 0.3 9.4 3.3 1.9 14.7 3.4 0.1 5.8 3.4 1.1 4.1 3.8 2.4 1.0 3.2 4.9 0.7 1.1 2.9 3.2 1.3 1.8 12.1 3.6 0.8 0.0 0.0 0.0 0.0 0.2 2.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 109.9 0.0 5.7 0.0 0.0 0.1 0.0 0.2 16.1 0.0 0.0 0.0 0.0 0.8 0.0 23.7 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 1.0 47.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.3 0.1 0.2 1.6 0.0 0.0 0.9 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.8 0.8 0.9 2.2 0.9 1.6 2.5 1.3 1.9 1.0 1.1 0.8 7.0 0.0 6.7 0.3 0.2 1.3 0.7 1.5 0.0 0.3 4.6 2.2 1.1 1.5 3.4 0.0 0.0 0.5 0.1 0.0 3.9 0.2 0.0 32.7 12.4 6.6 14.9 4.2 0.0 0.7 1.0 10.4 0.0 52.6 2.5 0.0 2.5 0.4 2.3 1.7 0.1 0.8 0.0 6.2 6.5 0.0 2.8 8.8 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 1.2 0.2 0.3 4.2 0.0 0.0 9.0 1.9 0.0 0.0 0.0 1.1 6.2 1.3 0.5 0.4 1.9 ARHGAP1 "CDC42GAP, p50rhoGAP, RhoGAP" ENSG00000175220 "Rho GTPase activating protein 1" Q07960 11 46677080-46700619 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 92.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004689, HPA008285" Approved Approved Approved Vesicles NA NA 11000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA004689: AB_1078194, HPA008285: AB_1078195" "unprognostic (1.06e-1)" "unprognostic (2.73e-1)" "unprognostic (2.05e-3)" "unprognostic (5.19e-2)" "unprognostic (2.48e-2)" "unprognostic (9.07e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (1.34e-3)" "unprognostic (1.24e-1)" "unprognostic (7.96e-2)" "unprognostic (1.35e-2)" "unprognostic (4.94e-1)" "unprognostic (4.79e-2)" "unprognostic (4.13e-2)" "unprognostic (3.49e-2)" "unprognostic (2.55e-1)" "unprognostic (9.24e-2)" 84.5 49.2 40.9 38.0 48.3 33.4 61.8 33.4 46.1 71.3 31.2 62.8 25.7 93.7 21.5 75.0 68.4 50.7 112.3 39.1 41.0 41.5 46.2 38.4 30.7 45.7 43.2 46.4 36.5 24.7 36.8 39.0 39.0 64.9 32.6 9.6 46.1 62.6 30.0 65.3 46.7 80.6 38.0 58.4 49.0 15.8 49.8 23.2 44.6 20.5 34.6 107.9 63.4 57.4 23.0 56.7 27.9 39.8 135.4 99.6 32.9 50.3 50.7 45.3 41.2 34.2 29.5 33.1 26.7 102.3 40.7 55.8 22.4 76.0 33.5 23.3 24.6 36.8 27.7 40.4 44.5 31.3 52.3 131.9 46.7 34.5 42.9 46.8 39.1 27.1 24.3 30.3 55.9 82.6 21.2 30.9 72.1 78.5 29.4 25.0 39.9 49.3 42.3 85.2 10.0 31.6 45.8 69.8 19.1 40.1 88.0 35.4 49.1 82.1 25.5 98.7 51.0 32.0 38.2 24.8 77.4 52.0 39.3 27.6 33.0 33.1 26.7 56.9 19.3 14.3 20.8 22.8 32.3 14.7 17.9 20.8 37.3 23.7 72.0 34.1 27.4 24.9 40.9 48.3 33.4 46.1 39.1 41.0 45.7 43.2 39.0 38.0 49.8 57.4 25.2 19.2 18.7 16.6 18.3 8.5 13.4 24.6 10.8 11.9 22.3 24.6 50.2 10.0 18.1 29.5 27.1 25.1 35.2 35.2 3.9 22.2 0.4 17.9 26.9 19.6 19.4 15.3 13.0 27.9 31.0 29.2 31.6 27.6 19.6 21.3 25.7 32.1 30.4 16.8 15.3 36.0 14.2 30.7 8.4 1.7 23.6 19.1 8.8 11.2 28.2 11.0 36.0 23.1 92.3 27.3 19.2 35.3 10.1 11.4 22.4 13.3 10.9 14.2 59.2 28.0 55.9 3.1 3.5 24.7 13.1 16.6 19.9 9.4 21.5 18.7 ARHGAP11B "B'-T, FAM7B1" ENSG00000285077 "Rho GTPase activating protein 11B" Q3KRB8 15 30624494-30649529 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 2.6;lymphoid tissue: 1.4" "Cell type enhanced" "Detected in many" "Early spermatids: 22.6;Erythroid cells: 37.4;Late spermatids: 21.7;Muller glia cells: 17.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 8.9;Karpas-707: 7.1" HPA064479 Uncertain Uncertain Vesicles NA NA "Cluster 20: HeLa - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "HPA064479: AB_2685272" 0.2 0.0 0.0 0.8 0.2 2.6 0.2 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 1.4 0.2 0.2 0.0 0.0 0.1 0.2 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.2 0.2 0.1 0.2 0.2 0.3 0.1 1.4 0.1 0.0 0.8 0.1 0.1 1.2 1.0 2.8 1.3 0.0 0.4 0.8 3.2 0.9 1.6 1.8 0.6 1.8 1.5 0.1 0.2 0.9 1.4 1.6 0.6 1.3 3.0 3.9 3.1 8.9 0.2 0.0 2.8 1.8 0.1 0.0 0.4 0.2 0.5 0.9 1.9 0.8 7.1 1.7 1.0 1.0 2.8 0.8 0.7 1.2 1.9 3.2 0.8 0.7 1.3 1.5 0.8 1.9 0.7 0.4 0.7 1.5 1.4 1.0 2.6 1.7 0.5 0.8 1.4 0.5 3.1 0.4 3.5 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.3 0.0 1.5 1.0 6.1 2.0 1.0 2.8 1.8 3.2 0.6 0.3 0.7 0.0 0.6 1.8 6.2 0.0 5.1 7.0 0.0 0.4 22.6 0.4 1.3 1.1 0.0 37.4 0.4 0.6 0.0 2.3 15.3 0.7 1.3 6.9 4.2 0.8 0.0 3.3 0.2 8.3 2.0 7.9 3.1 21.7 2.1 3.3 0.0 1.0 4.8 17.3 4.1 0.0 0.7 0.4 2.5 1.2 12.6 1.0 1.6 0.6 1.2 2.3 0.0 1.3 1.5 15.5 12.9 6.9 1.4 0.0 5.8 1.2 12.1 0.9 ARHGAP30 FLJ00267 ENSG00000186517 "Rho GTPase activating protein 30" Q7Z6I6 1 161046946-161069970 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 57.6;lymphoid tissue: 77.0" "Cell type enhanced" "Detected in many" "B-cells: 71.6;dendritic cells: 103.4;Kupffer cells: 77.8;Macrophages: 79.1;monocytes: 133.0;NK-cells: 268.8;T-cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 118.2;HL-60: 92.5;HMC-1: 123.4;Karpas-707: 93.1;MOLT-4: 75.8;THP-1: 90.9;U-266/70: 138.6;U-266/84: 97.7;U-698: 97.9;U-937: 72.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036300 Enhanced Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA036300: AB_10601117" "unprognostic (7.31e-2)" "unprognostic (8.83e-3)" "unprognostic (7.46e-3)" "unprognostic (1.77e-3)" "unprognostic (7.41e-2)" "unprognostic (1.68e-3)" "unprognostic (3.05e-1)" "unprognostic (6.78e-3)" "unprognostic (1.94e-2)" "unprognostic (3.89e-2)" "unprognostic (7.91e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (9.78e-4)" "unprognostic (1.18e-1)" "unprognostic (1.08e-2)" "unprognostic (6.64e-2)" "unprognostic (2.65e-2)" 12.1 4.9 3.1 55.9 3.6 57.6 5.3 3.7 4.3 3.4 3.3 8.1 9.5 2.9 2.8 14.1 4.5 10.2 2.8 2.9 3.6 3.4 6.6 25.2 77.0 6.1 4.5 2.0 2.4 1.4 1.8 7.0 5.4 3.4 8.4 0.6 6.4 2.3 2.6 19.8 23.9 8.0 5.0 75.5 11.6 2.3 6.3 63.7 2.9 2.7 61.2 13.8 6.5 6.8 0.8 0.1 0.2 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.3 1.2 118.2 0.6 0.0 0.1 2.3 0.0 0.0 0.2 55.3 0.2 39.7 0.2 0.0 0.0 92.5 123.4 0.0 1.2 0.1 0.0 0.1 0.0 56.8 0.3 93.1 0.0 1.0 75.8 21.3 0.1 0.7 0.1 46.8 0.6 1.6 0.0 1.0 0.7 0.3 0.2 0.7 0.2 0.7 0.8 90.9 0.9 0.1 0.7 0.2 0.5 138.6 97.7 97.9 0.4 72.3 0.1 7.1 29.6 33.1 32.9 32.2 25.1 11.9 21.9 27.1 21.8 12.6 17.9 25.0 48.5 19.3 46.4 15.0 23.8 33.5 3.1 3.6 3.7 4.3 2.9 3.6 6.1 4.5 5.4 5.0 6.3 6.8 1.5 3.2 20.5 0.3 71.6 5.6 3.3 6.8 0.0 0.5 5.2 2.9 1.3 2.8 13.8 0.0 4.2 0.6 103.4 0.5 0.0 3.4 2.2 6.6 1.2 2.3 0.0 14.5 0.3 6.0 1.9 1.9 3.1 13.7 68.3 0.0 6.1 1.7 55.5 0.0 0.3 0.4 8.2 77.8 44.6 0.7 0.3 79.1 5.4 14.0 133.0 0.1 268.8 0.5 1.2 12.5 0.2 0.0 49.8 5.4 0.0 0.5 15.3 3.0 0.0 1.0 1.9 0.1 0.1 9.9 24.6 4.5 105.1 0.2 0.5 16.7 ARMH3 "C10orf76, FLJ13114" ENSG00000120029 "Armadillo like helical domain containing 3" Q5T2E6 10 101845599-102056193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.2;dendritic cells: 10.5;Extravillous trophoblasts: 14.8;Granulosa cells: 11.5;Hofbauer cells: 12.6;Syncytiotrophoblasts: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050913, HPA053580" Approved Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA050913: AB_2681270, HPA053580: AB_2682198" "unprognostic (5.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.62e-1)" "unprognostic (3.41e-2)" "unprognostic (9.41e-2)" "unprognostic (9.55e-2)" "unprognostic (5.28e-2)" "unprognostic (1.92e-2)" "unprognostic (1.18e-1)" "unprognostic (6.03e-3)" "unprognostic (1.40e-3)" "unprognostic (2.76e-1)" "unprognostic (1.86e-2)" "unprognostic (1.16e-1)" "unprognostic (2.48e-1)" "unprognostic (3.85e-1)" "unprognostic (4.87e-2)" 10.4 9.1 5.9 12.0 7.6 21.8 9.9 10.2 7.3 11.2 8.0 12.5 12.8 10.5 9.4 14.3 10.5 9.2 16.6 5.7 7.3 10.0 12.0 11.8 12.7 7.1 8.2 11.2 10.1 16.4 7.9 11.0 6.1 10.8 13.2 16.3 9.5 10.5 19.7 12.2 12.2 12.9 6.0 13.6 10.3 8.9 6.7 13.1 10.0 19.8 13.3 10.8 10.1 7.9 23.2 17.7 15.5 19.1 12.9 17.3 13.9 20.3 24.0 20.0 16.9 12.2 18.6 17.0 13.5 22.9 14.5 17.7 20.4 22.4 18.3 17.9 18.9 30.3 15.9 14.6 15.2 21.3 26.4 16.0 17.7 22.6 19.9 23.4 15.3 15.3 0.9 15.9 16.6 14.4 16.5 13.8 8.5 18.8 11.6 16.0 28.1 11.0 16.4 18.6 7.3 12.1 15.8 10.9 21.0 15.8 28.8 12.4 15.1 10.5 17.1 9.8 14.7 15.4 17.0 17.1 16.9 23.7 7.9 19.4 7.3 7.4 5.9 8.7 5.5 6.1 6.2 4.5 7.7 7.0 4.8 4.9 1.9 5.2 10.7 7.4 6.0 4.7 5.9 7.6 10.2 7.3 5.7 7.3 7.1 8.2 6.1 6.0 6.7 7.9 8.8 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 7.4 6.0 0.0 0.0 0.0 0.0 0.0 11.2 10.5 0.0 1.9 7.8 0.0 6.9 6.8 1.9 0.0 0.0 0.0 9.7 14.8 2.7 0.0 7.7 0.0 11.5 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 9.9 0.0 0.0 2.2 0.0 0.0 7.6 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 16.3 3.9 5.7 0.0 0.0 ARPIN-AP3S2 C15orf38-AP3S2 ENSG00000250021 "ARPIN-AP3S2 readthrough" 15 89834308-89912882 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA040513, HPA047173, HPA049270, HPA052278" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" Vesicles "HPA040513: AB_2677015, HPA047173: AB_2679969, HPA049270: AB_2680696, HPA052278: AB_2681783" "unprognostic (1.27e-1)" "unprognostic (8.88e-2)" "unprognostic (4.94e-2)" "unprognostic (1.04e-1)" "unprognostic (3.25e-2)" "unprognostic (3.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.80e-1)" "unprognostic (1.84e-1)" "unprognostic (2.19e-1)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" "unprognostic (1.44e-2)" "unprognostic (1.27e-1)" "unprognostic (8.35e-2)" "unprognostic (2.29e-1)" "unprognostic (4.49e-2)" 12.3 12.8 12.4 7.9 14.1 5.9 11.5 14.5 13.3 9.2 10.7 14.6 10.4 9.1 11.4 12.8 9.1 8.1 19.4 11.2 14.2 13.9 23.4 10.2 5.8 14.6 15.1 10.6 20.3 10.9 10.2 9.3 15.0 11.0 15.0 10.9 10.3 8.7 22.0 10.3 9.6 9.4 13.2 9.5 9.4 12.0 15.0 9.0 11.2 15.2 8.0 11.0 10.0 14.9 11.7 25.0 19.5 26.1 27.7 12.5 13.9 20.3 22.8 25.5 25.5 8.1 26.8 6.2 20.8 17.1 21.6 14.2 15.9 17.8 17.2 12.6 14.7 8.6 11.2 18.4 16.1 4.2 6.6 15.2 14.7 15.1 15.2 13.8 23.0 7.5 8.3 14.4 19.8 16.6 6.4 7.0 20.2 29.7 6.0 5.0 7.7 4.1 24.4 13.3 6.1 9.9 36.3 35.2 27.9 25.1 23.3 8.9 11.8 22.6 16.8 31.4 13.0 4.6 13.0 6.6 19.1 5.6 17.0 13.1 26.7 11.8 6.8 23.1 9.1 7.2 8.4 7.5 20.0 6.8 6.2 6.2 18.7 10.9 16.8 8.4 9.3 16.9 12.4 14.1 14.5 13.3 11.2 14.2 14.6 15.1 15.0 13.2 15.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ARV1 ENSG00000173409 "ARV1 homolog, fatty acid homeostasis modulator" Q9H2C2 1 230978981-231000733 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 116.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035709 Approved Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA035709: AB_2674744" "unprognostic (2.32e-1)" "unprognostic (4.69e-2)" "prognostic favorable (1.33e-4)" "unprognostic (3.29e-1)" "unprognostic (1.42e-1)" "unprognostic (9.95e-2)" "unprognostic (5.66e-2)" "prognostic favorable (3.27e-5)" "unprognostic (1.37e-1)" "unprognostic (1.12e-2)" "unprognostic (9.57e-2)" "unprognostic (9.82e-2)" "unprognostic (2.31e-1)" "unprognostic (4.82e-1)" "unprognostic (5.63e-2)" "unprognostic (1.39e-1)" "unprognostic (8.12e-3)" 10.6 18.4 23.4 10.2 24.5 13.9 19.0 26.2 32.8 12.2 25.7 24.6 16.4 9.7 22.9 15.7 14.3 16.4 30.1 24.5 25.6 25.2 26.2 15.0 14.8 25.2 24.1 11.2 17.5 33.3 20.1 11.7 25.0 16.2 25.9 29.0 22.0 15.2 21.7 17.8 17.3 13.1 25.7 13.5 17.1 31.3 25.2 15.0 21.9 24.8 15.3 15.2 11.2 27.7 40.8 43.6 20.8 25.1 29.6 26.4 20.1 19.0 34.0 33.5 38.3 16.3 31.4 11.4 22.7 21.3 20.5 32.3 40.6 25.5 39.2 30.4 55.7 36.8 28.9 22.1 30.5 53.6 27.9 28.0 25.8 18.1 20.9 21.9 22.5 34.7 53.7 30.7 22.2 14.3 22.3 16.4 27.1 43.0 27.1 25.2 32.1 33.1 47.1 33.0 21.2 32.6 22.6 26.6 57.9 5.3 46.6 46.6 13.9 13.4 8.7 23.6 45.9 47.4 44.6 28.9 36.8 45.9 36.7 9.1 8.1 8.5 10.0 12.2 13.9 18.1 11.2 12.4 10.1 11.2 13.7 13.0 2.0 12.7 21.2 14.9 15.4 9.0 23.4 24.5 26.2 32.8 24.5 25.6 25.2 24.1 25.0 25.7 25.2 27.7 13.6 16.0 31.7 10.7 12.6 12.9 22.0 75.8 11.4 18.9 14.8 15.6 32.2 21.5 38.9 29.5 2.1 37.9 12.7 15.8 60.7 24.1 52.6 12.7 10.9 12.7 7.7 58.1 20.2 40.8 14.5 14.5 11.7 9.7 17.1 14.4 15.0 17.3 24.9 38.7 25.6 18.5 34.6 13.3 5.5 22.9 9.3 13.5 24.9 8.4 9.8 33.6 7.2 8.5 19.3 21.5 11.5 16.6 14.7 11.6 17.9 32.5 27.3 20.0 0.0 11.4 15.6 116.7 21.0 20.3 15.2 15.6 11.4 22.0 26.4 20.9 ASIP "AGTIL, ASP" ENSG00000101440 "Agouti signaling protein" P42127 20 34194569-34269344 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 14.8;heart muscle: 28.0;ovary: 41.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.4;dendritic cells: 44.1;Hofbauer cells: 15.1;Leydig cells: 12.5;Peritubular cells: 10.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 356 "plasmacytoid DC: 134.8" "Lineage enriched" "Detected in single" 356 "dendritic cells: 134.8" "Cell line enhanced" "Detected in some" "CACO-2: 3.2;HSkMC: 2.4;SK-MEL-30: 1.9;U-698: 1.9" "Not detected" "Not detected" HPA048636 Uncertain Supported Vesicles "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA048636: AB_2680471" "unprognostic (4.81e-2)" "unprognostic (7.46e-2)" "unprognostic (1.97e-3)" "unprognostic (3.26e-2)" "unprognostic (2.24e-1)" "unprognostic (3.07e-2)" "unprognostic (5.13e-2)" "unprognostic (4.57e-2)" "unprognostic (4.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (5.53e-6)" "unprognostic (1.02e-1)" "unprognostic (3.09e-1)" "unprognostic (1.27e-1)" "unprognostic (1.33e-1)" 1.4 0.6 0.2 0.0 0.5 0.3 2.4 0.1 0.4 4.2 0.0 0.5 0.0 2.0 14.8 0.1 4.0 0.1 28.0 0.1 0.1 0.9 1.3 0.3 0.4 0.2 0.1 41.7 0.1 0.0 0.6 0.2 0.6 1.5 0.0 0.3 0.7 0.2 0.9 5.7 0.8 0.0 0.0 0.3 0.3 1.5 0.2 0.2 0.3 1.2 0.5 0.5 1.1 0.3 0.0 1.1 0.4 0.4 0.2 0.7 0.1 0.1 0.0 0.0 0.0 3.2 0.0 1.2 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.7 1.7 0.3 0.5 0.0 0.0 0.4 2.4 0.0 0.0 0.0 0.1 0.0 0.7 0.6 0.9 0.0 0.3 0.2 1.7 0.0 0.1 0.6 0.3 0.3 1.4 0.0 0.1 0.2 0.2 0.0 0.2 1.9 0.5 0.3 0.2 0.3 0.5 0.5 0.0 0.3 0.4 0.4 1.9 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 134.8 0.0 0.6 0.2 0.5 0.1 0.4 0.1 0.1 0.2 0.1 0.6 0.0 0.2 0.3 0.4 0.0 0.6 1.3 0.8 2.5 0.0 0.0 0.0 0.0 0.3 0.5 27.4 0.0 0.0 0.0 0.0 0.2 44.1 0.0 1.9 0.0 1.1 0.3 9.2 1.2 0.0 0.0 2.1 0.0 0.2 5.6 0.0 0.4 0.0 0.2 2.5 5.8 15.1 0.0 1.8 0.0 0.0 0.8 7.0 1.7 12.5 2.1 1.8 1.0 0.3 0.0 0.0 2.5 2.5 0.1 0.0 10.5 0.0 0.1 0.0 8.3 0.0 0.0 6.6 0.1 0.6 1.7 1.9 0.2 3.1 0.8 0.6 1.0 0.0 0.1 ATG9A "APG9L1, FLJ22169" ENSG00000198925 "Autophagy related 9A" Q7Z3C6 2 219219380-219229717 "Predicted membrane proteins, Transporters" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 83.8;Late spermatids: 105.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059551 Uncertain Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "HPA059551: AB_2684060" "unprognostic (1.53e-2)" "unprognostic (4.03e-1)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (4.80e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (2.18e-5)" "unprognostic (8.99e-3)" "unprognostic (2.07e-1)" "unprognostic (3.55e-3)" "unprognostic (4.67e-2)" "unprognostic (4.21e-1)" "unprognostic (2.23e-2)" "unprognostic (4.84e-2)" "unprognostic (3.15e-1)" "unprognostic (5.61e-2)" "unprognostic (1.95e-2)" 25.6 23.6 27.2 17.3 29.0 44.7 19.2 27.8 36.6 19.5 10.0 25.6 31.4 24.1 14.2 31.4 18.8 21.8 42.1 30.0 24.3 20.0 25.9 23.7 19.4 29.0 26.7 20.4 28.1 31.2 17.6 30.7 26.2 21.6 21.8 24.6 23.9 22.8 116.8 32.1 29.7 28.1 24.3 21.7 22.8 62.2 27.6 15.7 18.4 62.7 21.2 22.7 22.7 28.6 29.4 35.7 26.9 64.0 50.3 55.1 35.9 52.1 56.1 67.3 60.2 52.9 38.8 7.7 43.7 79.8 54.7 58.0 43.2 56.9 49.6 22.6 70.7 55.7 90.1 63.9 54.9 14.1 40.6 56.7 91.4 68.7 63.0 60.9 68.2 18.6 75.6 27.0 46.2 38.3 12.2 33.4 19.5 28.5 26.9 16.9 36.7 30.2 40.0 38.6 42.6 25.7 52.0 46.7 46.5 52.0 17.3 39.3 52.5 67.0 32.3 28.7 47.1 15.5 14.7 11.2 55.7 33.9 37.2 6.5 12.4 6.3 7.2 18.0 7.2 5.6 5.6 9.1 8.5 3.6 5.4 6.1 11.2 9.7 22.6 4.1 7.1 11.6 27.2 29.0 27.8 36.6 30.0 24.3 29.0 26.7 26.2 24.3 27.6 28.6 0.3 0.0 4.5 12.7 8.2 7.8 7.6 10.6 8.6 18.9 0.3 0.3 33.2 17.2 7.1 0.0 14.6 26.8 4.1 44.0 0.0 0.2 83.8 0.6 1.5 10.0 13.8 34.7 15.2 0.5 24.4 9.1 11.7 0.8 10.2 0.3 16.8 37.1 11.5 21.9 14.1 17.6 6.1 13.3 7.0 105.9 14.0 4.8 10.6 5.6 7.0 20.5 9.2 9.5 12.5 0.3 27.6 8.6 6.7 13.4 39.3 0.3 4.7 15.7 13.1 7.1 5.5 54.9 13.8 14.2 11.1 34.8 7.5 0.8 18.5 10.5 ATP13A1 "ATP13A, CGI-152, FLJ31858, KIAA1825" ENSG00000105726 "ATPase 13A1" Q9HD20 19 19645198-19663676 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031798, HPA049717" Approved Approved Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA031798: AB_2674048, HPA049717: AB_2680858" "unprognostic (2.08e-1)" "unprognostic (4.92e-2)" "unprognostic (4.30e-2)" "unprognostic (7.29e-2)" "unprognostic (3.33e-1)" "unprognostic (4.40e-3)" "unprognostic (3.97e-3)" "unprognostic (1.73e-2)" "unprognostic (3.17e-1)" "unprognostic (2.60e-2)" "unprognostic (1.16e-2)" "unprognostic (9.43e-3)" "prognostic unfavorable (6.51e-4)" "unprognostic (2.26e-3)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (1.57e-1)" 12.9 17.0 7.3 21.8 6.5 16.1 13.9 5.4 8.6 17.1 12.3 15.6 18.6 16.2 8.0 15.6 15.0 14.0 9.7 7.4 7.9 12.8 12.9 14.0 21.4 7.9 6.5 20.8 21.1 23.4 18.1 12.9 6.9 15.1 13.0 8.8 17.7 12.6 12.8 16.2 22.2 11.6 6.1 26.4 16.7 15.8 7.6 15.9 20.2 5.8 17.5 13.9 14.4 9.0 32.8 45.2 24.3 52.8 38.2 25.3 66.1 28.9 40.1 24.5 24.9 43.5 54.3 44.9 48.6 34.4 14.0 17.8 37.2 37.0 13.4 16.5 77.6 24.6 48.7 34.5 39.3 46.8 70.1 36.7 34.2 26.5 31.8 27.1 17.9 32.1 43.0 97.5 24.7 53.9 31.8 33.7 44.5 40.6 54.7 25.0 17.4 100.9 25.8 44.7 33.4 56.7 26.8 42.6 30.0 11.4 26.9 50.6 28.7 51.5 7.7 59.2 35.3 78.8 50.6 26.8 36.0 59.6 39.5 0.0 3.5 3.5 2.8 5.6 3.1 2.2 3.3 3.1 6.5 1.9 2.1 2.7 0.1 1.4 8.6 5.0 2.9 2.4 7.3 6.5 5.4 8.6 7.4 7.9 7.9 6.5 6.9 6.1 7.6 9.0 11.3 9.6 5.8 12.1 22.7 5.9 7.4 8.2 9.6 12.0 13.0 8.5 5.5 11.5 9.0 14.7 18.8 20.3 12.5 28.5 1.9 19.1 10.3 11.5 9.8 9.0 18.6 11.1 11.2 18.4 18.2 10.2 31.6 13.6 5.7 16.2 10.8 13.2 20.0 5.0 11.0 22.9 12.2 12.2 9.5 5.1 14.0 18.3 7.2 7.5 13.6 12.6 8.2 9.0 11.0 15.6 22.4 9.8 50.4 11.9 28.6 6.6 12.8 10.8 6.6 9.2 11.4 14.7 14.6 12.6 6.1 15.3 13.9 20.2 22.2 6.4 ATP6V0D2 "ATP6D2, FLJ38708, VMA6" ENSG00000147614 "ATPase H+ transporting V0 subunit d2" Q8N8Y2 8 85987323-86154225 "Metabolic proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 60.5" "Cell type enriched" "Detected in some" 6 "Distal tubular cells: 209.4" "Cancer enriched" "Detected in many" 9 "renal cancer: 36.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 3.3;SuSa: 5.8;U-87 MG: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055327, HPA058496" Enhanced Approved Vesicles NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA055327: AB_2682784, HPA058496: " "unprognostic (3.79e-2)" "unprognostic (1.59e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (8.43e-3)" "unprognostic (5.36e-5)" "unprognostic (4.02e-2)" "unprognostic (1.16e-1)" "unprognostic (7.75e-3)" "unprognostic (2.32e-2)" "unprognostic (1.61e-1)" "prognostic favorable (2.20e-6)" "unprognostic (8.58e-2)" "unprognostic (1.77e-2)" "unprognostic (3.67e-1)" "unprognostic (1.97e-2)" 0.3 0.0 0.6 0.7 1.4 1.9 0.8 0.4 0.7 0.4 0.4 3.1 1.6 0.3 1.4 0.7 0.0 0.5 0.4 0.5 0.7 60.5 0.4 2.6 1.3 0.6 1.1 0.0 0.4 1.3 0.0 0.8 0.6 1.4 3.5 14.0 1.1 2.5 0.0 1.7 1.3 0.4 0.3 1.1 0.3 0.2 1.0 0.5 1.0 0.0 1.1 0.5 0.0 1.4 0.4 0.6 0.3 0.4 0.0 0.3 1.3 0.0 0.0 0.6 0.1 0.0 0.2 0.1 0.1 0.0 1.4 1.2 0.4 0.9 0.2 0.2 0.0 0.5 0.7 0.1 0.0 0.4 0.6 0.3 0.0 0.2 0.4 1.1 0.0 0.1 0.2 0.3 0.3 0.0 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.6 2.0 0.1 0.0 0.4 3.3 5.8 0.9 0.0 0.2 0.3 0.4 0.2 0.3 0.2 0.1 0.3 5.1 0.3 0.4 0.7 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.1 0.1 0.4 0.2 0.2 1.0 0.5 0.2 0.4 0.2 0.1 0.6 1.4 0.4 0.7 0.5 0.7 0.6 1.1 0.6 0.3 1.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.1 0.0 0.4 0.1 0.0 0.4 0.0 0.1 7.3 31.3 0.0 0.0 0.0 209.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 0.0 0.2 0.0 30.5 0.0 1.1 0.0 0.0 6.9 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.3 0.0 1.0 0.0 11.4 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.2 ATP6V1B2 "ATP6B2, HO57, VATB, Vma2, VPP3" ENSG00000147416 "ATPase H+ transporting V1 subunit B2" P21281 8 20197381-20226819 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 256.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1130.7" "Group enriched" "Detected in all" 10 "dendritic cells: 336.8;granulocytes: 1130.7;monocytes: 682.0" "Cell line enhanced" "Detected in all" "SK-MEL-30: 317.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008147 Enhanced Supported Vesicles NA NA 310000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA008147: AB_1845195" "unprognostic (1.90e-1)" "unprognostic (7.24e-3)" "unprognostic (3.62e-2)" "unprognostic (2.57e-1)" "unprognostic (2.84e-2)" "unprognostic (5.59e-3)" "unprognostic (1.76e-2)" "unprognostic (3.78e-2)" "unprognostic (4.68e-2)" "unprognostic (4.23e-3)" "unprognostic (1.29e-2)" "unprognostic (1.34e-1)" "prognostic favorable (8.41e-4)" "unprognostic (2.41e-1)" "unprognostic (2.09e-2)" "unprognostic (2.47e-2)" "unprognostic (5.25e-2)" 46.4 76.4 112.6 71.9 111.2 45.7 35.3 72.8 126.0 30.1 72.5 38.0 43.9 29.4 31.0 51.3 32.8 39.0 38.2 124.0 135.5 145.8 49.2 72.7 54.1 103.4 120.0 27.5 34.5 71.4 74.5 50.5 138.2 28.1 43.0 205.7 40.4 27.0 66.7 62.5 57.8 40.1 74.8 66.1 32.8 67.8 100.3 50.2 33.4 64.7 48.9 44.5 36.1 99.5 44.2 71.5 87.4 29.2 117.7 72.3 79.1 96.6 61.5 121.5 125.2 81.7 25.4 77.7 38.4 93.1 123.7 36.8 70.1 64.6 129.0 32.9 47.2 54.2 29.9 63.6 137.6 39.0 108.0 65.0 57.9 76.0 69.3 134.1 77.2 101.2 82.0 72.8 132.5 25.0 114.6 46.2 65.6 64.6 31.5 46.6 113.4 40.8 112.9 68.2 68.0 97.9 46.9 62.7 317.9 72.4 81.6 70.7 82.8 61.1 46.3 101.9 78.5 29.4 42.7 90.9 84.6 91.6 158.4 183.7 682.0 485.9 52.9 618.6 57.7 50.2 54.1 56.8 336.8 44.5 54.4 53.7 1130.7 50.8 576.1 82.7 73.0 622.6 112.6 111.2 72.8 126.0 124.0 135.5 103.4 120.0 138.2 74.8 100.3 99.5 16.6 25.6 20.7 20.5 28.1 58.0 28.4 52.1 33.0 106.1 18.5 15.6 17.6 25.8 28.8 29.5 102.2 109.2 38.9 23.3 80.3 43.2 40.8 20.2 13.6 24.1 74.4 35.8 64.3 38.5 56.4 38.8 25.0 35.9 22.2 22.3 25.7 34.7 178.5 190.1 68.0 21.4 36.7 185.2 178.7 24.4 19.6 167.6 104.9 30.0 169.1 51.5 20.6 27.6 29.0 45.2 19.7 28.2 20.7 17.4 75.0 256.7 18.0 137.8 13.1 29.3 34.2 121.6 55.3 43.3 71.6 124.6 27.1 23.1 24.7 20.1 ATP8A1 ATPIA ENSG00000124406 "ATPase phospholipid transporting 8A1" Q9Y2Q0 4 42408373-42657105 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.5" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1218.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.5" "Region enhanced" "Detected in all" "white matter: 84.5" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 27.5;Daudi: 46.3;HEL: 16.4;REH: 16.1;SH-SY5Y: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052935 Enhanced Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA052935: AB_2681992" "unprognostic (8.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (6.59e-2)" "unprognostic (6.82e-3)" "unprognostic (7.69e-2)" "unprognostic (2.02e-3)" "unprognostic (3.99e-1)" "unprognostic (2.99e-3)" "unprognostic (4.39e-2)" "unprognostic (9.71e-2)" "prognostic favorable (5.54e-10)" "unprognostic (2.43e-1)" "unprognostic (3.25e-1)" "unprognostic (8.21e-2)" "unprognostic (2.25e-1)" 2.8 8.9 5.8 9.5 26.7 23.4 3.7 3.6 18.3 2.1 0.0 12.8 4.2 2.4 12.2 2.2 2.4 2.5 8.4 14.5 11.7 3.8 1.7 11.8 15.0 9.5 4.4 16.2 7.0 36.0 2.2 2.4 9.5 8.3 11.7 19.4 4.4 5.3 10.0 1.7 8.9 2.8 18.1 9.0 12.5 2.1 9.5 9.9 39.7 15.6 11.8 2.5 1.5 84.5 0.0 0.1 0.4 27.5 0.1 0.1 0.1 0.1 0.0 0.0 0.0 3.0 0.4 46.3 12.6 0.2 0.0 2.4 6.5 0.1 0.0 7.4 4.5 16.4 1.6 0.7 0.1 4.0 0.3 0.4 0.0 0.0 0.0 0.6 0.2 10.3 0.0 5.1 0.0 2.0 6.0 1.4 2.0 1.9 0.6 16.1 0.0 5.3 9.5 0.6 4.9 14.8 0.3 9.4 0.0 1.1 3.1 0.0 0.4 0.0 2.0 0.5 0.0 1.7 0.0 9.4 0.7 5.6 0.2 0.0 0.6 0.6 3.7 0.2 1.9 1.5 1.1 4.1 0.6 2.5 1.7 4.4 0.5 2.2 2.5 2.4 1.0 0.6 5.8 26.7 3.6 18.3 14.5 11.7 9.5 4.4 9.5 18.1 9.5 84.5 26.1 28.9 80.1 136.1 23.3 1.5 1.8 0.6 2.2 19.7 4.0 1.5 14.4 0.0 5.3 5.5 81.3 0.0 52.9 48.4 3.9 0.2 4.6 1.3 1.3 13.6 84.6 13.9 295.9 2.5 0.1 4.8 19.9 4.2 8.2 26.5 16.8 1.1 1.6 62.2 255.9 28.6 0.0 8.8 4.6 2.9 3.4 8.9 3.6 31.9 5.1 2.2 33.0 144.8 1218.1 0.6 10.2 1.9 37.6 9.6 45.6 2.0 0.3 38.1 0.0 6.3 2.7 1.5 3.6 5.0 1.4 0.0 51.6 8.6 25.0 3.0 AZIN1 "OAZI, OAZIN, ODC1L" ENSG00000155096 "Antizyme inhibitor 1" O14977 8 102826308-102893864 "Predicted intracellular proteins" "Polyamine biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 261.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027948 Approved Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 41: Macrophages - Immune response" Vesicles "HPA027948: AB_10602391" "unprognostic (1.16e-2)" "unprognostic (4.81e-3)" "unprognostic (2.23e-1)" "unprognostic (1.41e-1)" "unprognostic (8.55e-2)" "unprognostic (3.41e-2)" "unprognostic (7.19e-2)" "unprognostic (1.51e-2)" "unprognostic (2.10e-1)" "unprognostic (2.24e-1)" "unprognostic (2.07e-3)" "unprognostic (4.33e-3)" "unprognostic (1.25e-2)" "unprognostic (1.08e-1)" "unprognostic (2.83e-1)" "unprognostic (3.08e-2)" "unprognostic (1.68e-1)" 61.7 48.1 45.7 48.1 50.3 141.1 57.8 44.8 51.2 55.3 43.5 49.1 66.6 44.4 30.3 52.7 64.0 43.6 51.5 51.9 50.5 39.4 78.0 40.1 58.1 48.1 48.2 38.7 136.6 38.3 31.6 82.8 48.1 52.5 53.6 57.8 47.7 49.5 41.9 32.7 80.8 44.5 53.8 35.9 52.2 35.7 46.7 58.6 67.5 30.9 60.6 62.3 27.3 60.0 320.4 81.7 129.0 92.6 122.7 83.3 77.6 145.4 168.5 103.5 106.8 87.1 217.5 148.0 111.0 121.9 64.3 119.5 113.8 114.5 165.8 244.7 57.4 147.4 30.1 72.3 156.0 81.0 120.7 58.9 136.1 72.5 182.4 92.2 72.8 86.0 112.6 124.0 165.2 92.6 201.8 59.3 144.9 239.3 123.0 87.3 136.5 84.2 108.2 146.7 208.2 327.3 49.1 100.0 144.3 209.9 131.7 84.7 85.9 83.2 83.9 135.7 118.6 122.3 104.2 207.4 98.3 120.1 117.0 73.3 57.7 68.0 31.2 64.1 36.7 43.7 40.8 29.9 55.9 27.5 33.1 32.1 68.5 40.1 64.5 44.3 50.0 65.7 45.7 50.3 44.8 51.2 51.9 50.5 48.1 48.2 48.1 53.8 46.7 60.0 56.3 60.9 27.7 30.0 59.6 93.8 121.1 52.8 93.4 31.5 64.0 39.8 46.3 28.6 52.8 42.3 37.5 148.7 54.0 48.4 52.8 39.6 62.6 95.1 37.9 34.9 84.9 62.7 35.9 50.5 55.0 55.5 59.1 85.4 68.5 31.9 33.5 65.0 54.7 23.5 31.9 77.3 63.1 72.8 127.2 107.9 49.7 86.0 64.0 23.4 53.0 50.4 32.0 30.2 23.7 66.6 44.0 32.4 97.6 106.7 114.6 52.6 167.6 42.3 19.7 36.0 57.1 34.5 30.7 90.8 82.3 261.9 71.6 26.2 66.0 117.0 AZU1 "AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC" ENSG00000172232 "Azurocidin 1" P20160 19 825097-832018 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Heparin-binding, Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "bone marrow: 1578.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4.5;Breast myoepithelial cells: 4.6;Endometrial ciliated cells: 8.9;Erythroid cells: 8.8;Respiratory ciliated cells: 4.5;Skeletal myocytes: 5.7;Spermatogonia: 6.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "neutrophil: 3.3" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.3" "Cell line enriched" "Detected in some" 15 "THP-1: 659.5" "Not detected" "Not detected" "HPA055851, HPA075964" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 320000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA055851: AB_2682943, HPA075964: " "unprognostic (1.12e-2)" "unprognostic (3.71e-2)" "unprognostic (4.44e-2)" "unprognostic (8.85e-3)" "unprognostic (1.62e-2)" "unprognostic (1.29e-1)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (3.32e-1)" "unprognostic (4.22e-3)" "unprognostic (2.58e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-6)" "unprognostic (1.11e-2)" "unprognostic (1.10e-1)" "unprognostic (2.46e-2)" "unprognostic (3.04e-2)" 0.8 0.2 0.4 0.0 0.4 1578.1 1.5 0.2 0.9 0.2 0.2 0.2 0.0 0.5 0.0 0.1 1.4 0.0 2.0 0.4 0.3 0.4 2.8 15.9 0.6 0.3 0.3 0.2 0.2 0.0 0.9 0.9 0.4 0.4 0.0 0.0 2.6 0.0 0.5 0.6 0.2 0.0 0.2 33.1 0.2 2.4 0.4 3.1 0.5 0.0 0.0 0.3 0.2 0.3 1.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 44.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.4 0.6 659.5 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.6 0.0 34.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.0 0.1 0.4 0.4 0.2 0.9 0.4 0.3 0.3 0.3 0.4 0.2 0.4 0.3 3.5 0.0 0.0 0.0 0.6 0.0 0.1 1.2 0.0 0.0 4.5 4.6 0.7 0.0 0.5 0.0 0.0 0.2 2.8 0.6 0.0 0.1 0.0 8.9 1.2 1.0 0.0 8.8 0.8 0.0 0.3 0.8 0.0 2.3 0.0 0.1 0.0 0.4 3.2 0.0 1.4 0.4 0.0 3.7 0.4 0.7 0.0 3.2 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.2 0.0 4.5 0.0 0.0 5.7 1.2 0.1 6.4 0.9 0.1 0.0 1.0 0.0 0.6 0.0 B3GALNT1 "B3GALT3, beta3Gal-T3, galT3, GLOB, P1" ENSG00000169255 "Beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)" O75752 3 161083883-161105411 "Blood group antigen proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 53.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 56.3;Cardiomyocytes: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 8.8;NK-cell: 22.1" "Group enriched" "Detected in many" 7 "granulocytes: 8.8;NK-cells: 22.1" "Cell line enhanced" "Detected in many" "RT4: 128.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041204 Approved Vesicles NA NA 400000 "Cluster 48: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA041204: AB_10795585" "unprognostic (3.85e-2)" "unprognostic (5.11e-3)" "unprognostic (3.02e-1)" "unprognostic (1.06e-2)" "unprognostic (7.83e-2)" "unprognostic (4.07e-2)" "unprognostic (9.26e-5)" "unprognostic (1.49e-2)" "unprognostic (1.12e-2)" "unprognostic (1.88e-2)" "unprognostic (3.44e-2)" "unprognostic (3.24e-1)" "unprognostic (2.09e-3)" "unprognostic (1.32e-1)" "unprognostic (4.90e-2)" "unprognostic (3.66e-2)" "unprognostic (3.19e-3)" 5.3 7.2 20.7 3.9 21.5 4.8 9.8 14.7 19.6 20.1 8.0 2.7 1.9 9.9 8.5 6.8 14.2 9.9 53.3 21.7 26.7 19.4 1.2 14.6 4.9 12.8 21.7 18.8 11.1 8.6 9.8 13.9 18.0 11.6 2.4 26.6 22.3 8.5 1.4 2.5 2.4 9.9 14.1 6.2 10.7 8.4 25.7 2.8 27.0 3.2 5.4 12.3 5.4 13.0 17.3 0.3 7.5 0.1 1.0 2.8 0.1 9.3 8.7 22.3 7.3 11.3 13.2 0.0 35.7 8.0 12.7 3.9 0.0 16.9 7.5 0.0 0.0 9.0 5.7 0.0 11.2 0.2 0.0 23.3 5.4 6.1 1.4 15.6 31.6 0.0 0.0 0.0 8.3 29.4 0.1 0.0 17.4 0.2 38.9 0.1 0.0 0.2 9.3 128.3 15.1 0.1 23.7 8.8 6.3 3.0 35.6 13.3 0.0 0.2 15.5 0.5 0.2 3.6 0.1 0.2 14.7 0.0 0.0 8.8 0.2 0.0 0.4 0.2 0.4 2.3 0.2 0.4 1.7 0.2 0.4 0.9 0.4 22.1 0.1 1.1 0.0 0.7 20.7 21.5 14.7 19.6 21.7 26.7 12.8 21.7 18.0 14.1 25.7 13.0 5.0 19.2 2.2 10.1 2.1 5.0 5.2 5.7 6.2 56.3 7.5 6.2 56.9 0.0 8.0 14.7 12.5 21.2 1.2 0.1 11.7 3.5 0.7 4.9 5.8 7.7 1.8 17.0 22.3 8.5 13.0 13.3 4.6 8.7 10.2 13.0 6.1 0.2 9.8 6.7 27.5 0.1 6.1 2.1 6.8 2.2 7.2 3.4 10.6 9.4 4.3 12.6 1.0 14.6 3.2 9.8 0.1 5.3 0.2 6.2 0.1 15.8 3.1 8.4 0.0 5.3 13.2 6.5 20.7 8.4 2.6 5.1 1.2 4.6 0.7 4.5 B3GAT1 "CD57, GlcAT-P, HNK-1, LEU7, NK-1" ENSG00000109956 "Beta-1,3-glucuronyltransferase 1" Q9P2W7 11 134378504-134412242 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 195.2" "Cell type enhanced" "Detected in some" "Astrocytes: 27.4;Bipolar cells: 37.0;Excitatory neurons: 37.2;Inhibitory neurons: 30.4;Muller glia cells: 116.2;Oligodendrocyte precursor cells: 33.2;Oligodendrocytes: 77.8" "Group enriched" "Detected in some" 11 "glioma: 10.8;prostate cancer: 3.5;thyroid cancer: 4.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Lineage enriched" "Detected in single" 12 "T-cells: 1.1" "Cell line enhanced" "Detected in some" "AF22: 23.1;HMC-1: 25.3;NTERA-2: 22.1;SH-SY5Y: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002500, CAB010893, HPA069468, HPA074314" Enhanced Enhanced Vesicles "Secreted in brain" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Vesicles "CAB002500: AB_563601, CAB010893: AB_1078474, HPA069468: AB_2686138, HPA074314: " "unprognostic (6.72e-2)" "unprognostic (3.97e-4)" "unprognostic (2.13e-2)" "unprognostic (1.40e-3)" "unprognostic (5.52e-2)" "unprognostic (2.60e-3)" "unprognostic (6.30e-2)" "unprognostic (1.96e-2)" "unprognostic (8.74e-2)" "unprognostic (2.72e-1)" "unprognostic (1.57e-3)" "unprognostic (1.58e-1)" "unprognostic (9.34e-3)" "unprognostic (3.87e-3)" "unprognostic (2.42e-1)" "unprognostic (4.07e-2)" "unprognostic (2.26e-2)" 0.2 4.2 146.6 0.4 135.6 1.0 3.9 114.3 195.2 0.4 32.5 0.9 0.5 1.4 0.2 0.2 0.4 0.3 0.3 191.8 85.5 1.8 5.8 0.6 2.1 133.6 145.2 0.2 0.4 0.0 4.5 0.1 118.9 2.8 0.1 23.8 1.2 0.4 0.1 0.5 0.6 0.1 115.0 1.4 34.9 0.9 133.6 0.4 6.2 0.2 0.4 0.7 0.3 176.0 0.0 0.0 23.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.7 3.9 0.0 0.9 1.2 1.6 0.0 0.0 0.0 0.7 0.1 0.2 0.0 0.1 0.1 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.1 22.1 1.1 0.0 0.4 0.0 1.7 0.0 0.1 3.1 8.4 0.0 0.0 0.0 1.5 0.1 0.0 0.1 0.0 2.3 0.1 0.0 0.1 0.0 0.1 0.2 0.1 5.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 146.6 135.6 114.3 195.2 191.8 85.5 133.6 145.2 118.9 115.0 133.6 176.0 0.1 0.0 0.0 27.4 0.1 0.0 0.0 0.0 0.0 37.0 1.2 0.8 1.1 2.8 0.0 0.0 4.2 0.0 14.4 0.1 0.0 0.0 1.8 0.1 0.1 0.4 1.8 0.4 37.2 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.4 4.7 0.1 23.5 30.4 0.0 0.0 0.3 0.0 3.9 0.0 0.2 0.0 3.7 0.0 116.2 15.5 33.2 77.8 0.0 0.0 0.4 7.5 0.9 0.0 1.9 0.0 8.6 0.0 0.1 0.2 0.2 0.8 0.0 0.0 0.1 3.8 0.0 0.0 0.3 B3GNT2 "B3GN-T1, B3GN-T2, B3GNT-2, B3GNT1, BETA3GNT" ENSG00000170340 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2" Q9NY97 2 62196115-62224731 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 115.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005997 Approved Approved Vesicles NA NA 99000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 14: REH - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA005997: AB_1845234" "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (1.23e-2)" "unprognostic (1.67e-1)" "unprognostic (1.51e-1)" "unprognostic (1.55e-2)" "unprognostic (2.13e-2)" "unprognostic (3.76e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.63e-1)" "unprognostic (1.11e-2)" "unprognostic (9.55e-2)" "unprognostic (3.05e-2)" "unprognostic (3.18e-1)" "unprognostic (1.25e-1)" 17.3 20.8 6.6 13.3 13.6 72.7 26.1 5.9 9.8 25.9 9.0 19.4 27.7 24.6 6.2 25.1 12.7 27.4 19.0 6.8 8.6 33.4 21.8 34.2 24.1 6.9 8.3 5.9 39.7 7.6 13.2 30.6 9.7 10.8 24.3 5.2 15.5 8.2 3.2 11.0 14.4 24.1 6.1 14.9 18.2 7.6 8.5 25.5 19.5 9.0 18.3 20.1 12.8 6.7 20.7 14.0 20.9 9.3 22.5 10.0 60.0 19.8 21.8 15.4 20.5 29.2 32.5 22.3 17.8 18.5 21.6 19.4 13.3 16.6 26.5 46.8 10.8 55.1 6.4 17.2 16.8 33.2 23.8 12.3 30.7 29.6 10.5 11.0 23.4 15.3 30.4 13.7 18.9 15.7 63.7 49.6 20.0 37.4 5.8 115.0 14.4 12.3 29.2 20.1 20.1 14.9 14.1 29.9 23.5 33.4 8.6 38.7 26.7 18.6 16.4 31.7 19.9 38.2 14.4 96.2 14.6 56.5 18.4 14.9 9.0 56.2 20.0 8.6 28.0 14.8 14.7 34.6 10.6 16.6 17.3 26.0 21.3 41.0 11.7 13.3 26.2 17.6 6.6 13.6 5.9 9.8 6.8 8.6 6.9 8.3 9.7 6.1 8.5 6.7 40.3 64.1 9.8 2.0 31.4 71.5 30.9 20.8 92.2 15.6 40.0 20.7 9.2 18.6 21.9 18.4 0.0 40.9 43.8 42.7 23.5 24.0 0.1 51.1 30.3 31.8 9.5 61.6 11.2 57.2 38.3 19.5 36.7 97.3 3.8 9.7 37.5 21.3 60.4 0.0 3.4 22.7 87.5 20.5 58.5 0.7 2.5 34.4 35.6 14.0 19.7 8.6 18.6 2.5 7.2 36.3 24.8 2.2 25.8 25.5 14.2 19.0 19.1 2.1 65.7 8.1 68.2 0.3 1.6 77.4 64.8 65.3 45.9 10.6 13.9 41.1 B4GALT5 beta4GalT-V ENSG00000158470 "Beta-1,4-galactosyltransferase 5" O43286 20 49632945-49713878 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Urothelial cells: 128.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 6.6" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077777 Approved Vesicles "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Vesicles "HPA077777: " "unprognostic (7.98e-2)" "unprognostic (5.27e-2)" "unprognostic (2.62e-1)" "unprognostic (1.88e-2)" "unprognostic (2.76e-1)" "unprognostic (1.61e-2)" "prognostic unfavorable (2.69e-5)" "unprognostic (1.73e-1)" "unprognostic (1.50e-1)" "unprognostic (1.39e-2)" "prognostic unfavorable (1.87e-5)" "unprognostic (1.04e-1)" "unprognostic (1.50e-1)" "unprognostic (3.30e-2)" "unprognostic (5.41e-1)" "unprognostic (2.07e-1)" "unprognostic (2.69e-2)" 28.7 47.8 14.7 21.7 14.5 93.7 18.6 14.6 16.1 21.2 6.5 24.9 25.3 23.5 8.6 37.3 18.5 31.5 20.5 15.5 18.1 22.8 25.8 27.3 9.6 14.7 19.2 19.0 12.6 11.3 12.6 27.2 15.4 17.1 23.7 7.7 19.0 21.9 67.1 7.9 21.3 37.6 14.6 27.6 25.8 22.3 19.0 8.1 11.5 24.3 11.5 51.4 17.2 12.0 48.8 55.0 71.4 30.4 72.8 49.3 62.4 23.5 43.7 104.8 50.0 71.1 59.0 14.8 98.0 39.0 99.1 75.4 45.5 35.0 61.3 45.6 12.5 39.4 28.8 42.9 22.9 51.6 73.7 74.3 32.2 45.5 21.8 96.5 64.8 25.9 64.5 8.9 30.8 24.1 3.1 47.3 37.4 47.8 35.3 26.6 61.9 21.4 50.6 34.0 84.9 43.0 83.6 105.3 47.8 52.5 24.1 70.0 50.1 62.7 50.5 33.6 49.8 10.9 10.0 35.2 32.6 48.5 40.7 1.4 1.0 2.6 1.4 1.0 1.5 0.2 0.6 1.3 0.7 0.3 0.1 0.9 6.6 1.2 1.1 0.6 0.8 0.4 14.7 14.5 14.6 16.1 15.5 18.1 14.7 19.2 15.4 14.6 19.0 12.0 39.5 16.0 43.1 36.2 5.8 18.9 27.3 39.7 7.4 8.3 17.3 18.2 18.3 42.9 84.5 36.8 10.4 23.4 21.3 61.3 1.9 35.3 5.2 59.1 28.4 42.7 34.3 33.2 52.1 19.7 27.7 27.3 17.9 100.8 83.2 36.2 58.5 22.7 24.5 11.8 59.5 21.3 40.7 28.2 81.5 6.8 19.9 45.0 21.4 30.9 21.4 5.6 20.6 25.6 42.5 39.7 34.1 32.7 7.3 66.8 13.4 33.5 57.0 4.9 26.3 29.9 25.9 10.3 16.0 27.5 17.5 5.6 17.4 33.1 20.0 128.9 BAAT BAT ENSG00000136881 "Bile acid-CoA:amino acid N-acyltransferase" Q14032 9 101354182-101385400 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Serine esterase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "liver: 721.0" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 996.7" "Cancer enriched" "Detected in many" 42 "liver cancer: 181.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.4;CACO-2: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021251, HPA021330" Enhanced Uncertain Vesicles NA NA 520000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA021251: AB_1845247, HPA021330: AB_2670674" "unprognostic (2.53e-2)" "unprognostic (1.81e-1)" "unprognostic (9.97e-2)" "unprognostic (9.33e-2)" "unprognostic (7.75e-3)" "unprognostic (4.68e-2)" "prognostic favorable (4.97e-4)" "unprognostic (2.14e-2)" "unprognostic (6.19e-2)" "unprognostic (4.43e-4)" "unprognostic (3.65e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (4.24e-7)" "unprognostic (1.74e-1)" "unprognostic (2.12e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 0.1 0.0 0.5 0.0 0.5 1.2 0.0 0.5 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 17.4 0.1 0.5 0.4 0.3 721.0 0.4 0.0 0.4 0.3 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.8 0.0 3.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.1 0.1 0.1 0.4 0.8 0.2 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.5 1.0 0.5 0.4 0.4 0.3 0.5 0.1 0.3 0.8 0.3 0.0 0.0 0.7 2.4 0.0 0.1 0.0 0.0 1.1 0.3 0.1 0.7 91.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.1 0.0 0.1 0.7 0.0 16.0 9.7 0.2 0.0 0.1 0.0 0.1 0.0 0.0 12.1 996.7 0.0 0.0 7.2 0.0 0.0 18.2 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.1 0.0 3.0 0.9 1.8 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.5 0.1 0.3 0.2 0.0 0.0 0.0 1.0 0.1 0.4 0.0 BAG5 ENSG00000166170 "BAG cochaperone 5" Q9UL15 14 103556545-103562657 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 127.7" "Group enriched" "Detected in all" 13 "Early spermatids: 1734.2;Late spermatids: 1796.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016429 Enhanced Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 83: Testis - Spermatogenesis" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA016429: AB_1845261" "unprognostic (3.02e-2)" "unprognostic (2.98e-2)" "unprognostic (1.05e-2)" "unprognostic (6.26e-2)" "unprognostic (2.54e-1)" "unprognostic (5.22e-2)" "unprognostic (1.99e-3)" "unprognostic (2.78e-1)" "unprognostic (1.04e-1)" "unprognostic (4.77e-3)" "unprognostic (2.34e-1)" "unprognostic (3.80e-2)" "prognostic favorable (1.58e-8)" "unprognostic (2.51e-1)" "unprognostic (1.52e-1)" "unprognostic (3.69e-2)" "unprognostic (2.53e-1)" 24.6 11.4 12.7 15.1 13.0 27.8 18.7 15.9 16.7 14.7 15.6 14.8 12.3 16.1 12.6 21.8 16.0 12.9 13.3 13.5 13.2 15.9 11.9 15.5 17.1 12.6 12.4 12.1 12.2 14.0 10.8 14.4 12.8 14.0 14.6 18.4 16.5 14.2 13.1 19.3 12.1 15.1 12.4 18.3 14.9 127.7 12.2 14.9 23.7 13.5 19.1 15.3 12.6 14.3 26.2 22.1 30.0 27.1 27.5 26.5 33.1 26.0 22.6 22.6 19.9 18.0 32.7 47.3 24.5 30.2 20.6 38.4 24.2 34.7 35.6 19.9 15.8 31.3 25.3 16.2 17.4 42.7 31.3 19.3 43.7 23.2 29.3 20.7 24.0 34.4 25.2 34.8 31.2 35.1 37.4 19.9 17.8 43.8 27.4 40.1 34.4 21.6 37.3 58.3 33.0 22.3 34.9 30.3 23.6 20.1 38.9 21.8 28.4 24.4 19.9 37.9 31.2 21.4 34.4 52.7 27.5 22.9 30.9 28.7 13.4 11.9 9.3 14.8 11.9 6.8 11.0 9.0 14.1 7.8 12.8 11.1 9.0 13.0 21.4 5.9 10.6 12.7 12.7 13.0 15.9 16.7 13.5 13.2 12.6 12.4 12.8 12.4 12.2 14.3 51.5 44.8 24.3 10.4 29.4 69.0 44.8 33.3 47.8 37.9 32.9 28.8 21.8 17.2 44.5 35.0 27.1 25.4 40.0 26.5 66.5 24.7 1734.2 78.6 43.7 41.2 31.7 29.5 18.9 19.1 17.7 31.7 26.0 89.5 32.3 19.3 52.5 25.6 22.1 75.7 14.7 25.0 32.6 29.2 26.4 1796.9 49.7 24.4 32.0 11.2 23.6 49.6 36.0 9.0 20.3 27.1 15.2 67.0 18.5 45.2 18.4 31.7 43.3 36.2 32.9 30.3 27.0 129.7 40.4 60.5 89.8 40.8 33.3 33.1 24.3 62.1 BCAS1 "AIBC1, NABC1, PMES-2" ENSG00000064787 "Brain enriched myelin associated protein 1" O75363 20 53936777-54070594 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 890.2;choroid plexus: 301.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 182.6;Gastric mucus-secreting cells: 202.9;Intestinal goblet cells: 371.4;Oligodendrocyte precursor cells: 538.8;Oligodendrocytes: 718.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "MCF7: 44.2;OE19: 90.0;RT4: 179.5;SK-BR-3: 368.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033558, HPA051816, HPA054745" Enhanced Approved Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "CAB033558: AB_2274632, HPA051816: AB_2681623, HPA054745: AB_2682590" "unprognostic (6.41e-2)" "unprognostic (1.01e-2)" "unprognostic (6.20e-2)" "unprognostic (7.23e-2)" "unprognostic (1.05e-1)" "unprognostic (2.43e-2)" "unprognostic (5.54e-2)" "unprognostic (1.86e-1)" "unprognostic (3.80e-1)" "unprognostic (1.19e-1)" "unprognostic (5.25e-2)" "unprognostic (2.91e-2)" "unprognostic (4.70e-3)" "unprognostic (3.95e-1)" "unprognostic (1.77e-1)" "unprognostic (1.75e-1)" "unprognostic (7.77e-3)" 1.2 0.2 506.5 6.4 627.9 0.1 3.4 551.3 890.2 7.3 301.2 69.5 19.0 1.3 2.2 7.2 1.5 8.6 0.4 421.4 525.8 3.3 0.4 2.9 0.6 749.3 660.7 0.4 0.9 0.0 1.0 0.1 649.9 33.4 74.3 0.2 22.3 0.3 0.5 1.4 31.1 2.8 584.8 0.5 159.8 3.4 562.0 0.7 0.3 0.8 6.5 35.7 7.5 724.7 0.0 8.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.7 0.2 0.1 0.0 0.2 0.6 0.0 0.0 0.0 27.8 0.2 0.0 0.3 4.0 0.0 0.0 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.6 0.0 44.2 0.1 0.2 0.2 90.0 0.0 2.3 0.0 1.2 0.0 179.5 0.2 0.1 0.0 368.6 0.4 0.0 12.2 0.0 0.0 0.0 0.1 3.2 0.0 0.9 0.5 1.0 0.9 0.0 0.3 0.3 0.1 0.0 0.2 0.0 1.2 0.6 0.4 0.1 0.0 0.2 0.0 0.0 0.3 0.1 0.1 0.1 2.1 0.1 506.5 627.9 551.3 890.2 421.4 525.8 749.3 660.7 649.9 584.8 562.0 724.7 0.8 9.6 1.1 1.6 2.8 0.8 6.3 8.5 0.6 0.1 6.2 1.9 2.2 7.2 35.9 3.7 0.0 0.2 0.4 182.6 1.9 2.9 15.6 9.4 11.1 0.4 8.4 0.0 1.6 22.5 0.1 0.8 202.9 11.8 4.5 0.0 0.4 0.1 0.1 0.0 2.5 371.4 18.3 0.0 2.5 16.1 0.3 1.7 16.0 0.0 0.0 0.8 0.0 538.8 718.8 22.9 102.0 0.0 1.0 21.3 12.0 0.1 100.5 0.5 0.0 1.4 2.2 15.4 6.1 0.3 0.3 0.0 1.7 0.4 35.6 56.7 BICD1 ENSG00000151746 "BICD cargo adaptor 1" Q96G01 12 32106835-32383633 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.8" "Group enriched" "Detected in many" 5 "Astrocytes: 198.8;Excitatory neurons: 267.2;Inhibitory neurons: 331.5;Microglial cells: 96.5;Oligodendrocyte precursor cells: 167.4;Oligodendrocytes: 131.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NTERA-2: 73.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041309 Approved Uncertain Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA041309: AB_10804000" "unprognostic (1.40e-1)" "unprognostic (1.18e-2)" "unprognostic (1.73e-2)" "unprognostic (2.10e-1)" "unprognostic (2.06e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-6)" "unprognostic (5.93e-2)" "unprognostic (4.57e-1)" "unprognostic (3.64e-1)" "unprognostic (8.19e-2)" "unprognostic (9.66e-2)" "prognostic unfavorable (2.33e-7)" "unprognostic (1.72e-1)" "unprognostic (1.74e-1)" "unprognostic (5.37e-2)" "unprognostic (1.36e-1)" 5.8 3.8 7.8 6.0 6.2 3.2 4.5 29.8 10.3 13.7 0.0 4.0 2.1 9.8 4.9 2.0 9.8 4.7 5.3 6.7 7.0 6.0 1.2 6.0 6.8 4.4 6.0 20.6 1.8 6.1 6.9 8.7 7.3 5.2 2.8 7.9 2.7 2.6 3.8 2.3 3.8 5.4 2.6 8.0 2.8 3.1 6.0 7.4 6.2 3.4 5.3 4.6 4.1 8.5 14.5 9.9 7.1 4.3 6.9 9.3 8.1 16.4 6.7 16.5 11.6 12.8 9.6 21.0 13.3 14.5 18.8 6.7 36.2 13.8 25.7 14.9 10.6 28.3 9.9 6.2 7.7 22.8 16.8 5.5 6.8 19.4 15.9 25.4 16.8 22.8 13.0 41.7 6.5 5.8 22.3 8.7 73.7 6.2 11.0 16.7 23.9 15.7 21.7 8.3 31.7 17.4 12.5 0.9 12.8 48.7 8.3 5.0 16.6 25.1 24.0 18.6 23.7 13.7 20.9 44.3 16.8 10.0 27.3 0.0 0.5 0.0 1.5 0.2 2.3 2.4 1.4 0.9 0.8 2.0 1.8 1.5 0.1 1.9 0.0 1.9 2.4 0.8 7.8 6.2 29.8 10.3 6.7 7.0 4.4 6.0 7.3 2.6 6.0 8.5 15.1 16.0 1.1 198.8 22.0 0.4 8.2 13.6 6.8 30.5 5.4 6.3 8.3 1.5 9.1 9.2 37.5 0.4 10.7 0.7 1.9 9.1 0.6 11.7 26.2 17.0 6.6 9.2 267.2 4.7 0.5 12.6 1.1 34.2 0.0 35.1 13.2 0.5 6.5 23.5 331.5 1.2 16.2 1.3 4.2 1.2 4.1 5.1 8.8 96.5 4.2 39.2 4.1 167.4 131.7 8.3 0.5 4.5 34.5 7.0 0.6 2.7 2.6 19.3 0.0 18.1 12.3 6.9 9.2 3.9 2.4 0.3 10.7 28.1 2.6 3.7 BLOC1S5 "dJ303A1.3, MU, MUTED" ENSG00000188428 "Biogenesis of lysosomal organelles complex 1 subunit 5" Q8TDH9 6 8013567-8064396 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 41.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025613, HPA077525" Uncertain Supported Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "CAB025613: , HPA077525: AB_2686843" "unprognostic (1.54e-1)" "unprognostic (8.21e-2)" "unprognostic (1.26e-2)" "unprognostic (1.24e-2)" "unprognostic (1.92e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (8.12e-4)" "unprognostic (4.24e-2)" "unprognostic (1.20e-2)" "unprognostic (1.47e-2)" "unprognostic (2.87e-2)" "unprognostic (1.00e-1)" "unprognostic (1.62e-3)" "unprognostic (1.83e-1)" "unprognostic (1.13e-1)" "unprognostic (6.16e-2)" "unprognostic (7.60e-3)" 6.8 7.0 3.6 6.3 4.2 3.9 10.5 3.9 4.7 8.1 3.0 6.4 4.2 7.0 6.9 6.6 6.4 6.1 6.0 3.3 4.7 15.7 11.4 5.9 9.9 4.4 4.2 9.9 4.7 9.6 3.1 6.8 4.5 6.5 5.8 5.2 4.7 9.2 6.5 6.4 5.0 6.6 4.0 7.4 6.0 3.7 3.9 15.6 10.1 8.6 10.6 6.2 5.3 4.6 6.1 7.0 14.7 18.9 15.7 18.8 9.6 6.7 9.4 9.5 9.4 13.6 5.8 21.8 43.9 8.6 10.8 5.4 10.8 5.4 13.6 20.6 11.5 13.1 4.8 25.8 13.4 23.2 14.8 8.4 13.4 9.6 14.4 14.5 17.3 17.3 27.7 3.9 13.6 6.7 26.6 15.1 7.9 14.3 9.4 21.5 17.0 33.8 17.6 5.4 13.5 7.2 6.8 10.3 21.3 26.4 12.9 11.8 7.2 15.1 10.7 8.9 5.9 16.5 37.3 19.7 6.2 17.9 15.9 16.2 9.4 18.3 11.8 12.3 15.7 18.9 15.3 15.2 16.6 17.7 15.2 15.9 2.3 19.6 6.7 7.2 15.2 11.8 3.6 4.2 3.9 4.7 3.3 4.7 4.4 4.2 4.5 4.0 3.9 4.6 18.1 12.8 6.9 0.0 14.6 6.0 8.3 6.8 8.6 7.0 7.1 9.9 7.3 0.0 7.9 25.8 2.1 12.5 15.6 5.9 35.2 9.9 7.5 11.5 12.4 10.7 1.8 7.2 0.0 8.7 9.2 10.6 7.7 19.5 16.5 14.5 0.0 0.0 7.8 6.7 0.0 6.9 2.0 0.0 6.1 7.8 9.6 11.0 3.6 0.0 10.7 13.2 12.3 0.0 0.0 10.1 3.9 12.4 7.3 8.4 6.7 41.8 7.7 8.4 0.0 12.4 9.3 5.8 14.4 8.9 7.5 8.2 12.7 22.5 6.6 7.5 BMP2 BMP2A ENSG00000125845 "Bone morphogenetic protein 2" P12643 20 6767686-6780246 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 155.9;Basal keratinocytes: 167.1;Distal enterocytes: 125.6;Suprabasal keratinocytes: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 31.6;HeLa: 19.6;hTERT-HME1: 17.8;RT4: 25.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA058610, CAB078457" Enhanced Vesicles "Secreted to blood" NA NA 24400 21000 "Cluster 19: Lung - Lung function" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB078457: AB_2532532, HPA058610: AB_2683777" "unprognostic (2.22e-2)" "unprognostic (9.32e-2)" "unprognostic (6.12e-2)" "unprognostic (3.56e-2)" "unprognostic (1.94e-2)" "unprognostic (2.48e-1)" "unprognostic (3.70e-3)" "unprognostic (3.12e-3)" "unprognostic (8.51e-2)" "unprognostic (8.46e-2)" "unprognostic (2.53e-3)" "unprognostic (5.39e-3)" "unprognostic (7.81e-2)" "unprognostic (3.76e-1)" "unprognostic (2.77e-1)" "unprognostic (3.01e-2)" "unprognostic (7.49e-2)" 18.6 1.6 1.2 4.0 1.5 1.6 6.0 1.3 1.6 5.2 0.9 15.1 6.6 5.2 0.6 5.5 3.8 16.1 4.0 1.8 1.4 3.9 5.8 18.8 1.9 1.9 2.2 2.8 9.2 3.2 2.3 11.5 2.1 1.9 13.6 1.3 2.1 1.2 2.2 10.6 9.7 2.6 1.5 12.4 20.7 0.5 2.1 0.4 18.9 2.7 1.8 17.2 6.4 2.2 0.1 0.3 0.0 0.0 0.5 0.2 0.0 0.8 3.4 0.0 0.0 31.6 0.1 0.0 0.5 1.1 0.0 10.5 6.2 2.7 0.0 0.0 5.5 0.0 19.6 0.1 1.5 0.0 0.8 0.2 9.2 0.0 17.8 4.0 6.3 0.0 0.0 0.0 0.2 0.0 0.0 6.0 0.8 3.7 0.8 6.2 0.1 0.4 2.3 25.0 1.1 1.6 7.3 0.0 0.0 5.5 0.0 6.5 1.5 1.8 2.7 0.0 0.9 0.3 0.9 0.0 3.0 1.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 1.5 1.3 1.6 1.8 1.4 1.9 2.2 2.1 1.5 2.1 2.2 9.4 80.1 155.9 0.3 1.1 167.1 45.1 11.0 70.0 0.4 1.4 2.2 4.7 42.9 10.5 1.8 0.0 0.1 3.8 125.6 0.0 23.3 0.3 1.7 34.8 24.1 11.3 0.0 1.1 9.8 0.2 20.2 33.6 3.0 8.8 1.9 41.4 3.4 3.6 0.0 3.5 23.8 0.0 2.9 16.8 0.2 5.9 2.9 8.8 2.8 0.6 6.2 0.0 8.5 1.4 33.5 60.3 0.0 1.3 47.5 28.3 2.1 0.8 0.2 19.7 36.5 48.8 0.0 0.3 43.1 119.3 0.1 2.1 4.3 48.2 43.3 BMP8A OP-2 ENSG00000183682 "Bone morphogenetic protein 8a" Q7Z5Y6 1 39491636-39529869 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 10 "thyroid gland: 91.6" "Group enriched" "Detected in some" 7 "Early spermatids: 42.2;Late spermatids: 164.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 7.0;HL-60: 5.8;U-2197: 22.2;U-266/70: 8.6;U-266/84: 7.9" HPA047254 Approved Vesicles "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA047254: " "unprognostic (9.62e-3)" "unprognostic (2.11e-2)" "unprognostic (7.79e-2)" "unprognostic (1.22e-1)" "unprognostic (1.37e-1)" "unprognostic (2.00e-1)" "unprognostic (2.91e-3)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-1)" "unprognostic (1.54e-1)" "unprognostic (5.33e-3)" "unprognostic (2.95e-9)" "unprognostic (2.62e-2)" "unprognostic (1.49e-1)" "unprognostic (2.28e-3)" "unprognostic (2.55e-2)" 0.5 0.8 2.1 1.4 3.7 1.3 0.2 2.7 3.7 2.3 0.0 1.0 1.4 3.3 3.8 0.5 3.4 1.2 1.1 2.7 1.6 0.9 0.3 0.4 1.8 7.0 3.5 2.9 2.6 0.8 0.5 0.4 4.7 1.2 0.6 1.8 1.2 3.5 2.6 1.7 2.1 5.1 4.1 1.6 0.9 3.3 3.2 5.8 91.6 0.1 0.5 0.9 0.5 9.4 0.4 1.1 0.8 0.5 0.1 0.1 0.6 0.2 0.0 0.0 0.0 1.2 0.2 0.3 0.1 0.1 0.1 1.0 0.0 0.0 0.0 0.8 1.0 0.1 2.0 0.1 7.0 5.8 0.2 0.2 0.0 0.0 0.0 0.1 0.0 2.2 0.3 3.7 0.0 1.6 0.2 1.2 2.0 0.2 0.1 0.8 0.1 3.2 0.0 0.3 1.2 0.2 0.3 0.3 0.5 1.0 1.0 1.1 0.2 0.1 0.8 22.2 0.1 8.6 7.9 0.5 0.2 0.7 0.1 0.8 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.3 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 2.1 3.7 2.7 3.7 2.7 1.6 7.0 3.5 4.7 4.1 3.2 9.4 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.2 0.0 0.2 0.1 0.0 0.0 5.7 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 164.4 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.7 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 BMP8B "BMP8, OP-2" ENSG00000116985 "Bone morphogenetic protein 8b" P34820 1 39757182-39788865 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.4" "Group enriched" "Detected in many" 5 "Early spermatids: 72.1;Late spermatids: 106.5;Plasma cells: 38.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "THP-1: 120.5;U-266/70: 33.7;U-266/84: 52.5;WM-115: 56.7" HPA047254 Approved Vesicles "Secreted to blood" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA047254: " "unprognostic (1.53e-3)" "unprognostic (7.29e-2)" "unprognostic (2.18e-1)" "unprognostic (6.64e-3)" "unprognostic (8.79e-2)" "unprognostic (3.44e-2)" "unprognostic (7.27e-2)" "unprognostic (7.56e-2)" "unprognostic (1.88e-1)" "unprognostic (7.41e-2)" "unprognostic (2.68e-1)" "unprognostic (4.72e-4)" "unprognostic (1.79e-2)" "unprognostic (3.15e-1)" "unprognostic (9.67e-2)" "unprognostic (8.68e-3)" "unprognostic (4.82e-1)" 1.7 5.6 2.1 1.5 2.0 0.8 0.9 1.1 5.3 2.1 0.1 3.8 5.4 1.5 3.3 1.0 1.3 0.8 1.0 2.8 1.8 0.9 0.6 1.3 0.7 13.4 3.5 0.8 7.0 1.8 2.7 1.5 3.3 2.4 2.7 0.5 1.7 2.5 0.6 2.0 4.1 0.7 2.8 1.5 1.8 2.2 2.6 0.4 4.7 1.6 0.7 1.6 2.1 4.7 2.7 4.5 0.3 3.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.8 5.4 0.1 1.8 0.0 0.7 0.4 4.2 0.0 0.0 1.0 5.8 4.9 3.6 0.3 0.1 0.6 0.9 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.6 18.1 0.2 3.7 0.1 2.5 0.3 2.8 1.8 2.7 15.9 5.7 4.0 2.7 13.0 3.4 4.3 0.3 13.4 0.9 3.1 120.5 0.0 0.1 0.3 1.1 0.2 33.7 52.5 2.0 0.0 3.7 56.7 0.2 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 2.1 2.0 1.1 5.3 2.8 1.8 13.4 3.5 3.3 2.8 2.6 4.7 0.0 0.0 1.8 0.0 3.5 0.4 0.6 0.2 0.0 0.5 1.1 0.8 1.2 0.0 0.8 0.0 0.0 0.0 0.9 13.5 0.0 1.0 72.1 1.1 0.6 0.4 1.2 0.0 0.4 3.4 0.0 1.7 1.1 2.3 0.0 0.3 0.4 0.0 0.4 0.0 0.3 2.0 0.0 0.0 2.7 106.5 1.2 0.8 5.4 0.0 0.7 0.1 0.0 8.0 1.8 2.2 2.2 0.7 38.9 0.4 5.0 0.0 0.4 0.5 0.0 1.8 3.4 0.8 0.4 0.4 0.0 0.0 0.7 0.1 1.2 0.8 BPIFB2 "BPIL1, C20orf184, dJ726C3.2, LPLUNC2" ENSG00000078898 "BPI fold containing family B member 2" Q8N4F0 20 33007704-33023703 "Plasma proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "salivary gland: 2294.3" "Group enriched" "Detected in some" 4 "Breast glandular cells: 6.1;Breast myoepithelial cells: 9.1;Early spermatids: 4.8;Late spermatids: 9.3;Prostatic glandular cells: 7.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 582 "Hep G2: 232.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049491, HPA060121" Enhanced Approved Vesicles "Secreted in other tissues" NA NA 36000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA049491: AB_2680792, HPA060121: AB_2684207" "unprognostic (1.94e-1)" "prognostic favorable (1.97e-5)" "unprognostic (2.24e-4)" "unprognostic (9.48e-2)" "unprognostic (9.81e-2)" "unprognostic (2.02e-3)" "unprognostic (1.72e-2)" "unprognostic (2.71e-1)" "unprognostic (9.28e-2)" "unprognostic (5.35e-1)" "unprognostic (8.19e-2)" 0.4 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.0 99.8 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 1.8 0.0 0.0 2294.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 232.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.1 9.1 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 BSG "CD147, EMMPRIN, EMPRIN, OK" ENSG00000172270 "Basigin (Ok blood group)" P35613 19 571277-583494 "Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Host-virus interaction" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1535.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1408.0;Syncytiotrophoblasts: 1654.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002427, HPA036048, HPA074870" Enhanced Approved Vesicles NA NA 340000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB002427: AB_563501, HPA036048: AB_2674917, HPA074870: AB_2686719" "unprognostic (1.88e-1)" "unprognostic (4.85e-2)" "unprognostic (9.53e-3)" "prognostic favorable (2.59e-4)" "unprognostic (3.34e-1)" "unprognostic (1.38e-2)" "prognostic unfavorable (5.48e-6)" "unprognostic (1.54e-3)" "unprognostic (1.55e-1)" "unprognostic (9.46e-2)" "unprognostic (4.48e-3)" "unprognostic (2.61e-2)" "prognostic favorable (1.95e-6)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" "unprognostic (7.30e-2)" "unprognostic (3.22e-1)" 378.6 518.8 652.6 154.5 615.4 431.3 313.8 575.6 847.5 320.6 975.8 543.5 231.3 413.3 259.5 245.1 323.1 176.2 1535.0 629.0 606.0 469.7 186.0 253.6 101.9 578.5 611.2 300.7 301.6 255.3 331.2 320.2 599.8 228.8 155.9 189.6 274.8 194.4 472.3 226.6 239.7 164.1 551.0 200.0 455.8 486.0 724.3 92.8 302.1 292.2 74.2 366.9 233.0 581.2 622.6 739.3 339.5 852.3 975.0 426.0 800.4 499.2 507.6 506.1 437.9 607.1 569.4 208.4 564.3 383.5 148.7 967.8 341.0 575.0 129.6 468.1 840.3 150.0 545.5 812.3 683.6 361.6 679.0 455.5 578.5 302.4 304.5 613.1 383.3 198.3 722.9 992.5 298.6 1015.8 261.6 706.6 901.9 353.7 408.3 522.8 301.2 745.2 655.9 412.1 561.0 539.1 984.4 408.1 769.7 257.9 432.3 1118.9 478.7 557.5 353.4 940.1 751.5 639.7 701.8 201.1 1066.9 510.2 712.8 189.0 324.7 348.9 226.4 245.9 200.5 115.0 150.7 218.4 209.6 93.2 114.0 144.7 474.8 173.5 284.2 235.2 192.0 434.0 652.6 615.4 575.6 847.5 629.0 606.0 578.5 611.2 599.8 551.0 724.3 581.2 313.5 22.4 31.5 75.1 101.5 208.6 176.8 668.0 91.0 157.7 202.8 187.6 80.6 128.7 253.4 286.9 204.3 1408.0 156.5 1140.1 146.8 580.9 261.6 156.6 296.6 246.7 255.1 1091.4 35.4 371.4 1095.5 279.8 192.1 190.1 116.2 181.1 132.1 96.9 416.7 139.7 31.4 337.2 510.6 137.8 179.6 600.2 300.4 139.8 506.9 122.7 264.5 495.5 221.4 20.6 30.7 458.0 929.1 336.7 192.4 172.8 450.7 306.7 178.8 269.2 203.8 74.3 235.6 347.9 604.4 127.7 156.7 1654.9 130.9 223.5 478.2 181.4 BTBD3 "dJ742J24.1, KIAA0952" ENSG00000132640 "BTB domain containing 3" Q9Y2F9 20 11890723-11926609 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.9" "Cell type enhanced" "Detected in all" "Endometrial stromal cells: 223.0;Oligodendrocytes: 254.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 241.1;HeLa: 186.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041424, HPA042048" Uncertain Supported Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA041424: AB_10794667, HPA042048: AB_10796469" "unprognostic (3.93e-2)" "unprognostic (2.25e-1)" "unprognostic (1.32e-1)" "unprognostic (3.56e-3)" "unprognostic (4.24e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (2.51e-5)" "prognostic unfavorable (6.94e-4)" "unprognostic (4.87e-2)" "unprognostic (2.95e-1)" "unprognostic (1.07e-2)" "unprognostic (7.05e-2)" "unprognostic (6.66e-2)" "unprognostic (7.68e-3)" "unprognostic (1.67e-1)" "unprognostic (6.29e-2)" "unprognostic (1.37e-2)" 11.2 22.1 20.6 7.1 34.2 12.2 12.7 66.2 80.9 16.9 12.3 21.4 10.7 18.7 7.9 9.9 15.4 13.4 13.9 79.6 30.9 11.6 7.7 12.2 4.1 30.5 24.7 11.5 13.7 11.2 8.9 42.0 23.1 15.1 17.5 42.5 13.9 10.6 15.9 20.7 10.9 16.5 24.2 7.8 27.3 14.7 23.7 10.8 11.5 13.2 3.1 18.4 10.1 64.7 7.0 19.5 52.1 241.1 10.6 11.3 14.0 21.9 14.0 24.3 15.5 11.2 10.7 2.0 18.1 31.7 9.6 18.1 27.2 15.4 39.1 0.1 24.1 7.1 186.9 23.9 11.1 11.6 4.2 20.2 18.8 21.8 17.5 13.4 13.8 12.0 12.7 18.8 24.3 5.1 14.0 10.7 25.0 29.0 5.5 18.4 10.4 7.0 22.2 34.0 22.7 40.0 60.8 24.6 53.3 27.9 14.4 11.5 10.7 13.2 33.6 12.4 24.6 6.9 9.9 0.3 8.6 3.2 87.6 0.0 1.2 0.1 0.0 1.7 0.0 0.0 0.0 0.0 1.4 0.1 0.3 0.0 0.3 0.7 3.5 1.0 0.0 0.6 20.6 34.2 66.2 80.9 79.6 30.9 30.5 24.7 23.1 24.2 23.7 64.7 17.4 16.0 8.4 24.5 2.8 16.6 10.8 8.0 18.8 15.3 15.2 11.9 16.5 10.0 8.3 5.5 79.2 23.3 1.0 41.0 3.9 9.8 8.3 51.3 223.0 25.0 20.9 4.6 46.9 8.3 4.0 15.6 28.5 55.8 2.5 9.4 33.5 8.5 8.5 65.6 38.0 9.4 10.2 4.8 13.4 13.6 16.4 6.5 14.2 39.4 3.2 17.7 1.0 61.9 254.9 9.7 25.9 8.6 2.7 13.2 11.4 6.6 24.1 56.9 6.6 19.9 18.6 10.0 16.1 11.7 17.2 21.8 1.8 42.0 13.3 11.3 BTN3A1 "BT3.1, BTF5, BTN3.1, CD277" ENSG00000026950 "Butyrophilin subfamily 3 member A1" O00481 6 26402237-26415208 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 59.1;NK-cells: 73.2;Plasma cells: 47.6;T-cells: 50.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA012565 Approved Uncertain Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA012565: AB_1845494" "unprognostic (2.82e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-3)" "unprognostic (4.72e-3)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (3.10e-2)" "unprognostic (9.31e-2)" "unprognostic (9.81e-2)" "unprognostic (8.60e-3)" "unprognostic (1.19e-1)" "unprognostic (2.41e-1)" "prognostic unfavorable (4.15e-5)" "unprognostic (2.45e-1)" "unprognostic (5.02e-2)" "unprognostic (3.26e-2)" "prognostic favorable (4.81e-4)" 19.2 20.7 10.2 44.8 11.1 29.6 20.1 9.8 10.5 21.2 10.3 24.8 28.5 28.0 16.0 11.9 22.5 30.5 12.1 9.1 12.1 12.8 18.9 41.4 63.4 16.4 10.9 35.1 13.1 13.1 13.7 19.2 12.5 16.5 28.8 3.6 23.9 13.5 12.8 24.9 35.1 21.3 12.2 84.0 31.3 5.0 11.4 33.1 11.5 14.5 52.6 20.0 17.4 12.0 7.4 6.2 9.3 9.5 25.9 27.5 1.2 6.2 24.1 13.5 39.4 0.3 16.7 19.7 20.4 11.2 20.9 5.1 3.0 9.7 8.2 19.5 6.4 10.4 8.5 4.7 11.8 9.5 9.3 15.0 5.6 11.8 5.4 20.4 19.3 31.0 2.5 25.3 5.5 0.6 17.6 6.6 1.0 3.3 2.1 24.2 4.0 45.2 8.3 9.4 4.9 9.8 3.4 7.1 13.5 1.4 6.5 4.0 4.8 10.3 2.6 3.1 5.9 41.8 45.9 7.3 15.6 21.4 8.4 53.8 11.1 28.8 44.7 11.7 40.4 18.8 27.8 42.3 9.1 10.5 24.1 32.0 23.9 40.5 12.9 4.3 36.0 28.0 10.2 11.1 9.8 10.5 9.1 12.1 16.4 10.9 12.5 12.2 11.4 12.0 24.8 16.0 6.5 0.0 27.1 4.2 3.9 3.5 2.2 4.3 8.6 8.1 4.2 11.5 8.5 5.5 0.0 5.5 59.1 8.2 0.0 7.4 0.1 5.5 10.4 18.0 4.8 13.3 0.0 3.2 4.3 9.9 9.2 10.3 25.9 14.0 11.7 3.9 7.2 0.0 0.0 17.3 2.0 19.2 6.1 0.8 3.7 15.4 1.8 0.0 13.7 1.9 73.2 0.0 0.0 2.2 6.3 2.6 47.6 5.4 15.9 1.3 6.7 0.4 0.0 6.7 5.5 0.0 0.1 3.6 3.3 1.5 50.1 8.4 7.4 5.0 BZW1 "BZAP45, KIAA0005" ENSG00000082153 "Basic leucine zipper and W2 domains 1" Q7L1Q6 2 200810594-200827338 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 3845.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047288, HPA053272" Uncertain Approved Vesicles NA NA 34000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA047288: , HPA053272: " "unprognostic (2.45e-2)" "prognostic unfavorable (4.28e-4)" "unprognostic (2.08e-3)" "unprognostic (1.56e-2)" "unprognostic (1.93e-1)" "unprognostic (3.31e-3)" "unprognostic (3.98e-3)" "prognostic unfavorable (5.10e-4)" "unprognostic (4.49e-3)" "unprognostic (7.93e-3)" "unprognostic (1.08e-3)" "unprognostic (8.97e-3)" "unprognostic (4.38e-2)" "unprognostic (3.04e-1)" "unprognostic (7.61e-2)" "unprognostic (8.03e-2)" "unprognostic (1.24e-1)" 130.6 129.1 30.3 97.5 33.0 219.6 88.7 37.7 40.9 65.5 49.2 98.4 64.6 66.6 58.4 120.8 53.4 93.1 56.4 33.9 36.9 88.5 227.0 73.5 97.9 36.5 36.7 62.3 62.6 72.4 30.7 105.2 35.3 99.6 90.6 45.8 61.2 61.7 101.7 47.9 71.4 80.1 39.1 62.8 69.0 170.9 42.1 123.0 74.4 75.2 109.4 164.6 61.4 45.4 296.6 230.1 309.4 187.1 305.2 353.3 221.6 425.2 501.8 281.2 244.5 360.7 195.3 142.5 144.7 339.7 186.1 159.8 284.9 512.6 521.8 154.6 151.3 370.8 453.9 280.1 244.5 420.9 199.6 205.3 233.5 373.2 398.9 244.6 495.4 132.3 328.5 234.0 379.3 236.6 387.9 201.3 392.4 120.1 575.4 293.1 333.4 148.6 256.1 435.2 188.9 218.7 325.5 120.9 226.1 255.5 126.6 216.7 555.0 416.8 242.9 255.2 276.6 286.1 428.6 377.8 341.2 209.3 312.1 236.7 140.7 168.5 177.9 173.4 207.2 102.0 126.0 167.5 162.6 87.1 112.4 156.7 117.0 218.5 195.1 75.5 171.5 294.6 30.3 33.0 37.7 40.9 33.9 36.9 36.5 36.7 35.3 39.1 42.1 45.4 207.3 86.6 108.1 31.3 148.5 198.5 318.5 310.7 125.7 37.1 159.0 89.8 18.1 82.9 290.3 90.1 18.8 115.4 263.2 127.5 138.9 250.2 927.0 108.3 145.3 149.0 96.7 72.8 28.7 233.1 164.3 181.2 72.4 150.0 196.9 72.7 99.2 262.4 114.1 58.9 32.1 113.3 183.1 88.6 194.0 3845.6 102.2 169.1 124.5 15.0 308.1 119.6 170.0 24.6 36.6 464.4 106.5 95.9 132.7 242.3 68.2 163.3 121.7 33.4 98.6 159.4 179.8 175.2 169.2 133.2 196.1 195.2 200.3 103.3 106.1 370.9 C11orf91 ENSG00000205177 "Chromosome 11 open reading frame 91" Q3C1V1 11 33698261-33700801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.5" "Cell type enhanced" "Detected in some" "Early spermatids: 16.6;Late spermatids: 4.0;Sertoli cells: 6.6;Spermatocytes: 12.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 16.2;hTERT-HME1: 10.0;HUVEC TERT2: 8.2;TIME: 12.6;U-2197: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047064, HPA050487" Uncertain Supported Vesicles NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA047064: AB_2679920, HPA050487: AB_2681142" "unprognostic (9.22e-3)" "unprognostic (1.51e-2)" "unprognostic (1.76e-1)" "unprognostic (6.60e-2)" "unprognostic (1.62e-2)" "unprognostic (3.63e-2)" "unprognostic (2.31e-1)" "unprognostic (5.68e-3)" "unprognostic (7.41e-2)" "unprognostic (2.97e-2)" "unprognostic (1.99e-2)" "unprognostic (3.01e-1)" "unprognostic (8.33e-2)" "unprognostic (4.06e-2)" "unprognostic (3.95e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" 4.8 0.2 0.3 0.6 0.3 1.0 1.5 1.2 2.0 0.1 0.0 0.4 0.0 0.2 0.1 2.9 0.3 4.7 0.8 0.2 0.5 1.4 0.2 1.1 0.2 0.3 0.5 0.2 1.5 0.0 0.1 0.5 0.6 0.2 0.0 0.2 0.5 0.2 0.5 1.0 0.3 0.8 0.4 0.0 2.1 9.5 0.3 0.2 0.4 0.0 0.4 1.4 0.3 0.6 0.2 0.0 0.2 1.5 0.0 0.0 0.0 1.8 0.0 0.9 0.4 0.3 0.6 0.0 0.1 1.9 0.2 0.7 0.5 16.2 1.3 0.5 0.0 0.0 4.0 0.9 0.3 0.0 0.0 0.0 0.1 1.2 10.0 0.5 8.2 0.2 0.0 2.5 3.9 0.0 0.0 0.3 0.0 0.1 5.0 0.0 0.0 0.0 1.1 2.1 0.0 0.3 0.0 1.6 0.1 0.5 0.0 0.0 12.6 1.2 0.3 10.3 0.3 0.7 0.6 0.0 2.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.2 2.0 0.2 0.5 0.3 0.5 0.6 0.4 0.3 0.6 1.2 0.0 0.0 0.3 0.0 0.0 2.2 0.0 0.0 0.0 0.4 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 16.6 0.4 0.2 0.6 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.3 0.1 0.0 6.6 0.1 0.3 12.3 0.4 0.3 0.0 0.1 0.0 0.0 0.0 1.5 C12orf29 DKFZp434N2030 ENSG00000133641 "Chromosome 12 open reading frame 29" Q8N999 12 88033846-88050160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039663 Uncertain Approved Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA039663: AB_10795253" "unprognostic (8.66e-2)" "unprognostic (1.39e-1)" "unprognostic (7.80e-2)" "unprognostic (6.88e-2)" "unprognostic (2.51e-2)" "unprognostic (2.06e-2)" "unprognostic (1.75e-3)" "unprognostic (4.72e-3)" "unprognostic (1.07e-2)" "unprognostic (1.84e-1)" "unprognostic (8.81e-2)" "unprognostic (6.49e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.03e-1)" "unprognostic (9.29e-2)" "unprognostic (2.03e-2)" "unprognostic (2.42e-1)" 4.7 9.8 7.5 4.5 8.1 8.7 11.0 7.0 10.0 6.5 4.9 4.8 4.8 6.6 12.8 16.1 4.5 5.2 5.8 8.1 7.8 8.4 12.6 5.1 6.8 7.5 7.8 7.5 5.9 7.2 3.1 5.3 7.6 8.2 5.1 5.4 8.3 6.1 4.3 15.5 3.9 5.6 7.8 5.3 5.2 5.6 7.1 6.2 9.9 8.7 8.7 7.4 6.0 8.8 13.1 8.1 7.9 9.2 16.7 21.5 5.8 17.1 14.6 14.4 12.9 7.8 5.0 24.0 2.3 8.8 8.1 11.3 15.5 11.8 24.8 10.4 15.9 20.5 6.5 6.9 20.1 26.9 9.4 14.7 17.8 13.5 16.8 16.8 11.2 9.2 20.3 4.8 22.7 4.6 18.0 13.6 12.0 11.0 15.7 10.4 13.5 19.9 16.3 10.4 19.0 17.0 9.8 22.8 12.5 6.5 14.6 19.2 9.0 12.9 4.3 13.3 13.4 10.7 16.0 14.5 10.0 19.1 11.4 4.5 0.8 0.6 2.7 0.8 4.9 2.0 3.9 3.3 1.0 1.7 4.6 3.9 0.0 3.4 0.9 1.4 2.1 1.8 7.5 8.1 7.0 10.0 8.1 7.8 7.5 7.8 7.6 7.8 7.1 8.8 20.4 9.6 13.6 7.8 17.7 51.5 29.2 29.1 21.6 14.4 19.0 17.8 16.1 20.0 29.6 5.5 6.2 15.3 16.1 5.1 37.2 21.5 34.2 14.2 16.8 17.7 7.8 44.6 22.8 24.2 17.1 26.4 8.2 19.1 10.8 6.7 9.7 16.4 9.6 10.1 20.0 8.9 18.3 6.6 11.7 22.8 32.0 6.6 26.6 4.7 5.3 16.2 11.3 5.0 12.9 22.3 5.0 30.9 13.5 39.7 4.2 33.3 19.7 17.8 6.6 24.9 25.2 50.4 31.7 29.5 71.5 9.3 21.3 8.6 13.0 31.2 C12orf75 "AGD3, OCC-1, OCC1" ENSG00000235162 "Chromosome 12 open reading frame 75" Q8TAD7 12 105235290-105396097 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 109.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 841.2;Ductal cells: 626.3;Endometrial ciliated cells: 579.1;Extravillous trophoblasts: 1228.2;Proximal tubular cells: 762.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 661.2" "Group enriched" "Detected in all" 6 "dendritic cells: 661.2;T-cells: 169.9" "Cell line enhanced" "Detected in all" "BJ: 877.8;BJ hTERT+: 517.0;fHDF/TERT166: 432.7;RPTEC TERT1: 425.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065311 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA065311: AB_2685463" "unprognostic (5.96e-2)" "unprognostic (3.85e-1)" "unprognostic (9.86e-2)" "unprognostic (1.02e-1)" "unprognostic (6.73e-2)" "unprognostic (8.58e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (8.61e-2)" "unprognostic (1.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.33e-1)" "unprognostic (7.00e-2)" "prognostic favorable (1.69e-5)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.00e-1)" "unprognostic (4.47e-3)" 12.2 7.3 4.3 8.9 4.7 11.3 11.6 9.4 7.2 31.3 2.1 24.9 9.2 18.5 6.1 8.7 20.9 38.2 2.5 4.1 8.8 58.5 2.0 7.5 14.7 5.3 5.5 6.6 33.8 20.1 3.5 9.3 4.9 41.2 22.0 2.8 4.2 109.3 32.0 9.5 8.8 6.7 6.5 6.3 49.9 26.6 8.8 10.8 2.9 11.8 19.1 5.0 27.0 5.4 43.6 66.6 16.5 14.9 61.2 117.3 30.3 877.8 517.0 194.2 109.4 133.2 3.6 12.2 348.9 432.7 31.7 70.4 36.6 50.3 212.9 241.1 65.0 38.8 17.7 26.5 7.7 29.8 37.7 49.6 12.0 66.4 73.8 113.0 26.1 69.9 1.9 58.8 192.4 14.4 115.3 262.5 39.6 15.8 153.3 21.6 44.3 11.2 425.3 4.3 73.5 18.4 36.9 7.7 16.2 45.2 22.6 7.1 44.2 201.7 77.2 77.0 118.1 34.9 57.6 58.8 44.5 9.7 55.3 39.0 0.7 1.2 165.5 0.5 80.4 19.7 69.2 169.9 23.3 16.2 19.8 102.4 3.5 69.4 1.6 661.2 144.1 88.3 4.3 4.7 9.4 7.2 4.1 8.8 5.3 5.5 4.9 6.5 8.8 5.4 12.8 3.2 2.8 1.6 61.2 100.2 65.9 21.9 38.7 4.5 32.2 26.9 1.1 271.7 20.9 187.6 4.2 35.3 519.5 469.8 841.2 626.3 152.3 579.1 32.6 14.8 333.2 15.8 2.7 222.3 1228.2 53.0 160.5 293.1 2.5 9.7 13.2 1.8 31.9 63.9 2.9 63.6 85.5 5.3 97.3 324.1 15.5 48.2 60.5 40.3 29.1 6.4 299.7 0.5 0.4 420.0 175.5 4.9 160.3 87.0 102.1 762.3 129.7 4.9 6.6 8.6 127.8 102.9 118.6 37.1 61.2 40.6 143.0 0.7 63.9 37.3 C19orf84 ENSG00000262874 "Chromosome 19 open reading frame 84" I3L1E1 19 51388289-51390591 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "testis: 22.1" "Cell type enriched" "Detected in some" 10 "Spermatogonia: 31.9" "Group enriched" "Detected in some" 5 "ovarian cancer: 1.3;testis cancer: 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "K-562: 6.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA068082 Uncertain Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Vesicles "HPA068082: AB_2685949" "unprognostic (5.94e-2)" "unprognostic (7.72e-2)" "unprognostic (8.51e-2)" "unprognostic (1.43e-3)" "unprognostic (2.08e-1)" "unprognostic (1.47e-1)" "unprognostic (2.13e-3)" "unprognostic (9.28e-4)" "unprognostic (1.31e-1)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (3.84e-1)" "unprognostic (2.61e-7)" "unprognostic (8.30e-3)" "unprognostic (1.86e-1)" "unprognostic (2.92e-2)" "unprognostic (3.99e-3)" 0.0 0.0 0.4 0.2 0.4 0.6 0.0 0.4 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.0 0.1 0.3 0.4 0.5 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.4 0.0 22.1 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.4 0.4 0.7 0.4 0.4 0.4 0.5 0.5 0.3 0.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 2.2 0.3 0.3 0.0 0.0 0.2 0.0 3.1 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 31.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 C1GALT1C1 "C1GALT2, COSMC" ENSG00000171155 "C1GALT1 specific chaperone 1" Q96EU7 X 120625674-120630054 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010666, HPA015632" Approved Approved Vesicles NA NA 21000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 51: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA010666: , HPA015632: AB_1845625" "prognostic unfavorable (5.66e-4)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (1.98e-1)" "unprognostic (3.07e-2)" "unprognostic (5.26e-3)" "unprognostic (4.34e-2)" "unprognostic (2.50e-1)" "unprognostic (2.18e-2)" "unprognostic (8.10e-2)" "unprognostic (3.85e-2)" "unprognostic (3.07e-1)" "unprognostic (3.98e-2)" "unprognostic (4.48e-2)" "unprognostic (1.55e-1)" "unprognostic (6.05e-3)" "unprognostic (3.78e-2)" 15.3 27.8 4.2 8.7 4.6 2.8 14.5 4.9 5.6 15.7 6.4 15.7 10.1 12.2 16.8 14.8 13.7 8.3 17.7 4.2 5.9 13.8 21.0 12.0 8.8 4.9 5.2 9.7 15.8 16.3 33.9 9.2 4.9 10.5 14.5 6.3 20.0 11.1 7.8 5.8 13.2 9.5 4.8 13.0 13.5 6.1 4.5 7.4 13.2 7.0 9.6 11.5 12.8 5.2 15.9 15.1 8.2 14.2 126.7 24.0 13.0 28.4 39.9 14.7 27.7 9.9 49.8 10.3 13.9 57.6 28.4 21.9 16.2 13.9 23.4 17.6 19.6 6.6 13.1 14.7 19.7 11.7 10.1 21.0 12.1 18.3 6.1 36.9 47.0 5.1 4.2 11.8 17.5 21.6 3.9 11.0 9.3 53.3 15.1 1.8 6.4 28.5 29.9 10.6 9.0 8.6 27.0 18.4 14.6 15.0 15.9 11.2 43.4 6.7 8.3 27.2 26.9 5.1 7.9 8.2 24.6 22.7 15.0 12.1 12.3 20.4 12.0 16.4 13.3 12.3 15.4 13.0 14.6 7.6 15.6 12.5 22.7 12.3 13.6 16.7 15.8 12.2 4.2 4.6 4.9 5.6 4.2 5.9 4.9 5.2 4.9 4.8 4.5 5.2 27.1 6.4 10.4 6.5 16.3 6.8 22.7 107.9 15.4 8.3 17.6 10.0 17.6 14.3 75.9 38.6 2.1 56.9 16.3 18.7 15.6 40.3 2.7 30.5 20.2 27.6 13.8 5.9 4.7 44.3 51.7 34.7 10.7 25.3 2.5 14.5 21.4 22.3 24.1 20.2 6.5 20.8 77.3 16.2 11.4 6.4 22.7 19.6 30.2 3.7 20.7 17.5 15.5 5.5 10.1 30.0 20.8 19.2 50.1 10.7 16.9 20.3 71.0 10.5 6.6 18.1 24.4 6.5 8.4 14.1 7.2 20.0 15.2 25.8 21.5 20.5 C1QTNF12 "ADIPOLIN, C1QDC2, CTRP12, FAM132A, MGC105127" ENSG00000184163 "C1q and TNF related 12" Q5T7M4 1 1242446-1246722 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.8;skin 1: 6.6" "Cell type enhanced" "Detected in some" "Adipocytes: 19.5;Extravillous trophoblasts: 11.2;Proximal tubular cells: 45.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "EFO-21: 4.1;U-2 OS: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024107 Uncertain Approved Vesicles "Secreted to blood" NA NA 38200000 "Cluster 40: NK-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA024107: AB_2101207" "unprognostic (1.10e-2)" "unprognostic (5.68e-3)" "unprognostic (3.45e-1)" "unprognostic (1.24e-2)" "unprognostic (6.60e-3)" "unprognostic (2.43e-1)" "unprognostic (2.67e-3)" "unprognostic (1.01e-2)" "unprognostic (2.58e-1)" "unprognostic (1.05e-2)" "unprognostic (8.02e-3)" "unprognostic (1.10e-2)" "unprognostic (9.68e-3)" "unprognostic (1.48e-1)" "unprognostic (2.47e-1)" "unprognostic (1.09e-1)" "unprognostic (1.20e-1)" 1.3 0.1 0.4 0.2 0.4 0.0 0.7 0.3 0.5 0.5 0.0 3.4 6.8 0.3 0.0 1.3 0.5 0.1 0.8 0.4 0.7 3.4 0.5 0.4 0.0 0.8 0.4 0.2 0.2 0.0 0.3 0.2 0.5 0.3 0.7 0.0 0.3 0.0 0.4 6.6 6.7 0.0 0.4 0.2 0.4 2.4 0.9 0.0 0.4 0.0 0.1 0.3 0.6 0.5 0.1 0.0 0.0 0.3 0.2 0.0 0.8 0.6 0.0 0.0 0.0 0.3 0.2 0.0 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.1 0.1 0.4 0.3 0.1 0.1 0.0 0.7 0.0 0.0 0.6 0.1 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 4.0 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.5 0.4 0.7 0.8 0.4 0.5 0.4 0.9 0.5 19.5 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 2.9 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 3.9 0.5 0.0 0.6 1.2 0.7 0.0 0.0 0.0 0.8 11.2 0.5 0.0 0.7 2.5 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 45.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.4 0.3 0.0 0.0 C1QTNF7 CTRP7 ENSG00000163145 "C1q and TNF related 7" Q9BXJ2 4 15339818-15446167 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.8;Fibroblasts: 32.3;Leydig cells: 22.7;Peritubular cells: 31.6;Skeletal myocytes: 15.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 4.2;ASC TERT1: 2.8;HSkMC: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007055, HPA051797, HPA055392" Uncertain Approved Vesicles "Secreted to blood" NA NA 238000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB007055: , HPA051797: AB_2681614, HPA055392: AB_2732596" "unprognostic (6.61e-2)" "unprognostic (4.50e-2)" "unprognostic (6.16e-2)" "unprognostic (6.50e-4)" "unprognostic (1.24e-1)" "unprognostic (4.98e-3)" "unprognostic (2.31e-2)" "unprognostic (7.69e-3)" "unprognostic (7.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.97e-4)" "unprognostic (3.01e-3)" "unprognostic (8.31e-2)" "unprognostic (7.56e-3)" "unprognostic (7.28e-3)" 7.8 1.4 1.2 1.6 1.2 0.0 4.7 1.2 2.6 23.1 0.0 8.6 1.2 16.5 10.2 6.0 6.3 14.0 7.0 0.8 1.8 5.5 1.2 10.8 1.2 1.1 1.8 20.9 0.8 0.1 1.1 7.2 0.9 9.5 4.2 0.1 2.5 3.2 0.6 3.2 3.8 12.0 0.6 9.7 9.0 1.7 1.8 0.4 3.8 6.6 0.5 10.3 10.3 1.3 0.0 0.0 0.0 0.0 4.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 2.6 0.8 1.8 1.1 1.8 0.9 0.6 1.8 1.3 1.2 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.0 15.8 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.1 0.2 6.5 0.5 0.0 0.0 1.0 0.0 0.3 32.3 0.0 0.6 0.0 2.0 0.0 0.0 0.1 1.7 4.4 0.0 0.0 0.0 3.2 0.5 22.7 0.3 5.4 6.5 0.0 0.3 0.0 2.5 0.7 0.0 0.0 31.6 0.2 0.1 0.0 2.8 0.0 1.2 6.6 15.2 9.9 0.0 0.1 0.6 3.0 0.0 0.7 5.7 0.0 0.1 C2CD4C "FAM148C, KIAA1957, NLF3" ENSG00000183186 "C2 calcium dependent domain containing 4C" Q8TF44 19 405445-409147 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.4" "Cell type enhanced" "Detected in some" "Adipocytes: 13.2;Excitatory neurons: 3.6;Granulosa cells: 3.7;Hepatic stellate cells: 3.6;Rod photoreceptor cells: 7.6" "Cancer enhanced" "Detected in many" "testis cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.4;MCF7: 4.4;NTERA-2: 6.2;SCLC-21H: 11.1;U-2 OS: 6.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055915 Uncertain Approved Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA055915: AB_2682968" "unprognostic (1.29e-1)" "unprognostic (9.43e-2)" "unprognostic (5.79e-2)" "unprognostic (1.64e-1)" "unprognostic (9.39e-3)" "unprognostic (2.14e-1)" "unprognostic (1.67e-1)" "unprognostic (9.81e-2)" "unprognostic (1.81e-1)" "unprognostic (1.36e-1)" "unprognostic (1.19e-1)" "unprognostic (1.35e-1)" "unprognostic (1.12e-2)" "unprognostic (1.43e-2)" "unprognostic (5.04e-2)" "unprognostic (5.09e-2)" "unprognostic (1.74e-1)" 3.8 1.0 9.8 0.3 11.4 0.0 3.0 3.7 17.4 3.0 2.5 1.3 0.4 2.3 0.0 0.7 2.0 2.8 4.8 10.8 17.1 2.5 0.7 1.8 0.1 7.5 7.6 0.3 1.0 0.1 2.6 0.4 8.8 1.0 0.0 0.8 0.3 0.0 0.9 0.8 1.4 0.1 8.7 1.0 0.8 2.0 13.0 0.1 3.9 0.5 0.0 0.6 1.0 7.1 0.0 0.5 1.5 1.3 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.1 2.0 0.0 0.5 0.0 0.7 2.4 2.4 0.2 0.1 6.4 1.3 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.4 0.2 0.0 0.0 4.4 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 11.1 3.2 1.0 0.0 0.0 0.5 0.2 0.0 0.0 0.1 6.5 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 11.4 3.7 17.4 10.8 17.1 7.5 7.6 8.8 8.7 13.0 7.1 13.2 0.0 0.0 0.3 0.1 0.3 0.3 0.3 0.0 0.5 0.3 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.2 1.9 3.0 0.0 3.6 0.4 0.0 0.1 0.0 0.2 0.0 3.7 3.6 0.1 0.0 0.0 3.1 0.0 2.0 0.0 0.4 0.3 0.0 0.0 0.0 1.9 0.0 2.0 0.0 3.0 0.6 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 7.6 0.0 0.4 0.4 0.7 2.2 0.0 0.3 0.0 0.1 0.0 0.0 0.1 C4orf47 LOC441054 ENSG00000205129 "Chromosome 4 open reading frame 47" A7E2U8 4 185426249-185449826 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 24.3;fallopian tube: 13.6;retina: 15.1;testis: 13.3" "Cell type enhanced" "Detected in many" "Early spermatids: 191.3;Endometrial ciliated cells: 50.0;Excitatory neurons: 36.6;Respiratory ciliated cells: 106.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 2.4;hTERT-RPE1: 4.9;U-87 MG: 5.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA043662, HPA063485" Enhanced Uncertain Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA043662: AB_10964715, HPA063485: " "unprognostic (3.38e-2)" "unprognostic (2.66e-1)" "unprognostic (5.78e-3)" "unprognostic (2.84e-3)" "unprognostic (3.61e-3)" "unprognostic (1.31e-1)" "unprognostic (5.82e-5)" "unprognostic (3.72e-2)" "unprognostic (4.62e-2)" "unprognostic (2.84e-1)" "unprognostic (1.25e-1)" "unprognostic (8.71e-3)" "prognostic unfavorable (4.75e-4)" "unprognostic (1.05e-1)" "unprognostic (3.64e-2)" "unprognostic (9.88e-3)" "unprognostic (1.50e-1)" 0.5 0.3 3.2 0.2 4.4 0.3 2.1 3.8 2.9 1.0 24.3 0.3 0.1 1.2 3.8 0.3 13.6 0.9 0.9 3.3 3.6 2.7 0.4 2.0 0.1 7.2 8.2 0.7 0.7 0.6 2.9 0.2 5.5 0.6 0.2 15.1 0.5 0.6 0.1 1.0 0.2 0.3 7.1 0.2 0.3 13.3 3.9 0.2 4.6 0.1 0.2 0.3 0.3 3.9 2.4 0.0 0.2 1.2 0.4 2.3 0.7 0.0 0.1 0.2 0.3 0.3 1.4 0.1 0.4 0.1 0.2 0.2 0.3 0.4 0.5 0.5 0.4 0.0 0.1 0.3 0.5 0.0 0.1 0.5 0.5 0.5 0.2 4.9 0.0 0.5 0.3 0.1 1.8 0.3 0.0 0.0 0.3 0.0 0.9 0.0 0.0 0.2 0.7 0.0 1.3 0.6 0.4 0.0 1.5 0.5 0.1 0.4 0.7 0.4 0.1 0.0 0.0 1.0 0.0 0.0 5.9 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.2 0.0 0.0 3.2 4.4 3.8 2.9 3.3 3.6 7.2 8.2 5.5 7.1 3.9 3.9 0.6 3.2 1.5 21.5 2.0 0.6 0.9 8.7 4.6 0.9 2.2 3.9 0.6 1.5 13.2 3.7 10.4 0.1 0.4 0.4 1.9 2.8 191.3 50.0 1.5 1.3 0.0 0.0 36.6 0.6 1.5 2.4 6.6 3.4 0.0 0.3 1.1 0.1 0.2 1.7 26.3 0.0 2.0 0.6 0.4 20.9 0.6 0.7 1.8 4.7 0.1 3.6 0.0 18.6 13.4 1.0 0.0 0.7 9.6 0.6 0.0 3.7 106.6 14.8 0.0 3.0 3.1 12.6 5.0 2.6 0.6 0.3 1.5 0.5 0.0 0.3 C7orf61 IMAGE:4839025 ENSG00000185955 "Chromosome 7 open reading frame 61" Q8IZ16 7 100456620-100464260 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 68.4" "Group enriched" "Detected in many" 20 "Early spermatids: 588.7;Late spermatids: 349.4" "Cancer enriched" "Detected in some" 5 "glioma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 25.2;NB-4: 9.6;TIME: 14.9" HPA060395 Enhanced Approved Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA060395: AB_2684274" "unprognostic (1.88e-1)" "unprognostic (5.02e-1)" "unprognostic (1.26e-2)" "unprognostic (7.70e-5)" "unprognostic (1.65e-1)" "unprognostic (2.63e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (4.26e-1)" "unprognostic (2.25e-1)" "unprognostic (4.43e-2)" "unprognostic (2.53e-1)" "unprognostic (6.39e-13)" "unprognostic (9.54e-2)" "unprognostic (2.93e-1)" "unprognostic (1.33e-2)" "unprognostic (1.24e-2)" 1.3 0.6 11.5 0.5 14.7 1.4 0.9 12.5 13.4 2.0 7.4 1.6 0.0 0.9 0.3 0.9 1.4 0.5 1.2 11.0 12.4 1.0 0.8 1.6 0.8 13.7 13.3 3.0 0.3 0.2 2.9 0.6 13.1 1.5 0.1 1.9 0.5 0.6 0.5 0.8 0.9 0.2 11.1 2.6 0.7 68.4 12.7 0.8 1.1 0.6 0.3 1.1 1.3 16.3 1.0 0.2 0.8 0.9 0.9 2.2 0.3 0.4 1.5 0.2 0.8 1.1 0.5 0.7 1.7 0.9 1.4 0.7 0.3 0.0 0.6 1.0 1.7 1.4 2.2 0.0 1.2 0.5 0.4 0.3 0.4 0.9 1.4 2.4 25.2 2.4 0.7 1.3 1.5 2.4 0.5 9.6 0.6 0.3 1.1 2.5 0.0 0.5 0.4 0.4 0.0 0.0 0.6 0.8 1.5 0.5 0.4 2.6 14.9 1.3 2.2 2.8 0.4 0.3 0.2 1.0 0.3 2.3 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.3 0.3 0.2 0.1 0.0 0.6 0.0 11.5 14.7 12.5 13.4 11.0 12.4 13.7 13.3 13.1 11.1 12.7 16.3 1.7 0.0 0.0 16.0 1.0 8.3 0.5 0.7 4.6 1.7 2.9 5.5 1.4 1.5 0.4 0.0 0.0 0.2 1.7 0.4 0.0 0.5 588.7 0.8 1.2 2.2 0.0 0.0 1.2 0.0 0.4 2.0 0.0 1.1 0.0 1.5 0.7 0.0 0.9 3.3 1.5 0.4 0.0 0.3 16.8 349.4 7.8 1.4 5.4 0.0 0.7 7.4 0.0 4.5 14.1 0.2 0.1 3.8 0.0 0.7 0.5 0.1 0.4 0.1 6.6 1.7 1.8 22.9 2.6 1.6 6.1 0.1 2.2 0.4 0.4 0.4 CA10 "CA-RPX, CARPX, HUCEP-15" ENSG00000154975 "Carbonic anhydrase 10" Q9NS85 17 51630313-52160017 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 54.9;cervix: 21.8;retina: 44.5" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 1607.5" "Cancer enriched" "Detected in some" 4 "glioma: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 1.2;RT4: 2.1;SCLC-21H: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054825, HPA057837" Supported Approved Vesicles "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA054825: AB_2682617, HPA057837: AB_2683542" "unprognostic (2.66e-1)" "unprognostic (1.76e-1)" "unprognostic (6.06e-2)" "unprognostic (2.10e-1)" "unprognostic (3.43e-1)" "unprognostic (8.22e-2)" "unprognostic (4.43e-3)" "unprognostic (1.02e-3)" "unprognostic (1.01e-1)" "unprognostic (5.91e-2)" "unprognostic (1.46e-1)" "unprognostic (7.21e-3)" "unprognostic (9.18e-5)" "unprognostic (1.60e-1)" "unprognostic (1.51e-1)" 0.0 3.2 22.9 0.0 21.0 0.0 0.0 54.9 27.2 21.8 7.9 0.4 0.3 0.2 0.0 0.0 0.4 0.1 0.0 23.0 20.6 7.2 0.0 0.0 0.0 33.4 19.3 1.9 0.2 0.0 3.9 1.0 33.4 0.0 0.1 44.5 1.2 0.0 0.0 0.0 0.5 0.1 19.5 0.0 0.1 10.2 30.6 0.0 0.0 0.0 0.0 0.1 0.1 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.2 2.1 6.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 21.0 54.9 27.2 23.0 20.6 33.4 19.3 33.4 19.5 30.6 17.6 0.0 0.0 0.0 8.8 0.2 0.0 0.0 0.0 0.0 211.9 0.0 0.0 0.4 0.0 0.0 3.7 4.2 0.0 0.1 0.0 15.6 0.0 134.5 0.0 0.0 0.3 0.0 0.0 343.6 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.0 17.0 0.0 0.0 0.0 0.2 84.4 1.2 0.1 0.0 14.0 0.0 5.1 0.0 1607.5 4.2 0.0 0.0 0.7 0.1 0.2 0.0 0.2 0.0 11.9 0.0 0.1 0.0 1.5 1.3 0.0 0.0 0.1 2.2 0.0 0.0 0.1 CAAP1 "C9orf82, CAAP, FLJ13657" ENSG00000120159 "Caspase activity and apoptosis inhibitor 1" Q9H8G2 9 26840685-26892803 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA020404, HPA024029, HPA024100" Uncertain Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA020404: AB_1845841, HPA024029: AB_1845842, HPA024100: AB_1845843" "unprognostic (1.07e-1)" "unprognostic (2.35e-1)" "unprognostic (1.73e-2)" "unprognostic (6.74e-2)" "unprognostic (8.83e-2)" "unprognostic (1.35e-2)" "unprognostic (4.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-2)" "prognostic favorable (1.27e-5)" "unprognostic (1.46e-1)" "unprognostic (1.89e-1)" "prognostic favorable (7.94e-9)" "unprognostic (2.74e-2)" "unprognostic (7.57e-2)" "unprognostic (1.46e-1)" "unprognostic (1.43e-2)" 7.0 20.4 4.3 10.5 4.5 7.7 10.8 4.8 6.2 9.1 11.0 18.6 17.4 8.2 16.9 11.3 9.2 9.8 5.7 4.4 5.1 16.3 23.8 7.8 14.7 4.4 4.3 6.6 10.8 18.9 7.4 9.7 4.3 10.6 19.5 8.6 11.2 9.5 7.1 10.2 12.7 10.0 4.0 8.5 11.2 12.6 4.6 14.2 27.4 7.5 15.1 10.6 6.8 4.7 24.2 14.9 24.3 23.9 15.9 13.4 18.5 17.4 17.1 16.4 20.1 4.4 14.9 28.6 17.5 14.9 9.4 12.8 25.3 17.0 22.4 39.0 15.4 49.6 22.6 28.2 26.4 21.7 23.9 13.7 21.4 12.7 29.7 18.5 27.8 18.4 14.1 21.0 19.1 13.9 33.8 9.0 32.2 23.8 12.3 23.1 10.9 19.0 42.6 17.7 19.4 38.5 15.9 17.5 16.3 21.5 14.9 25.6 16.7 0.0 24.5 10.1 16.4 9.6 19.2 33.0 8.0 22.3 10.3 14.9 11.3 8.2 16.2 17.6 20.9 18.8 17.7 18.9 18.4 18.7 14.7 15.3 1.4 20.1 15.7 17.2 18.8 16.0 4.3 4.5 4.8 6.2 4.4 5.1 4.4 4.3 4.3 4.0 4.6 4.7 13.9 22.4 21.6 42.1 20.3 9.9 11.3 18.4 15.9 10.8 18.2 14.6 9.7 14.3 27.6 31.3 8.4 18.3 16.4 28.1 58.7 20.6 18.8 25.6 15.3 14.9 15.5 21.7 34.0 19.8 14.7 13.4 18.8 25.5 18.3 15.8 10.4 34.3 12.1 8.4 42.5 26.0 26.4 11.1 10.3 5.4 8.4 17.7 8.8 26.2 15.6 22.1 12.3 41.2 33.8 22.6 23.1 6.4 26.0 17.5 13.4 29.5 23.7 12.7 13.1 16.9 14.8 41.9 18.4 31.6 14.6 10.8 20.1 28.0 32.1 12.6 CAB39L "bA103J18.3, FLJ12577, MO2L" ENSG00000102547 "Calcium binding protein 39 like" Q9H9S4 13 49308650-49444064 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 200.0" "Cancer enhanced" "Detected in all" "prostate cancer: 28.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 41.8;RT4: 43.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003686, HPA045954, HPA076632" Approved Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB003686: AB_426084, HPA045954: AB_2679512, HPA076632: " "unprognostic (3.90e-2)" "unprognostic (1.09e-1)" "unprognostic (4.13e-1)" "unprognostic (5.01e-1)" "unprognostic (3.29e-1)" "unprognostic (1.94e-1)" "unprognostic (2.82e-1)" "unprognostic (2.94e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (3.08e-2)" "prognostic favorable (7.91e-4)" "prognostic favorable (1.94e-13)" "unprognostic (6.59e-2)" "unprognostic (8.31e-2)" "unprognostic (4.96e-2)" "unprognostic (8.05e-3)" 23.7 37.4 25.0 4.4 26.4 2.2 37.3 21.0 20.7 14.5 68.2 57.7 6.0 15.3 16.3 31.2 18.3 16.5 22.0 24.6 38.7 14.0 5.3 19.5 4.2 24.6 35.0 21.5 12.0 29.2 8.4 12.4 25.1 41.4 11.6 14.8 16.9 22.5 7.5 16.1 12.5 11.5 27.4 4.0 27.1 33.4 31.4 9.4 9.7 13.0 5.2 26.5 17.3 28.4 1.6 1.7 9.8 2.8 9.3 8.7 14.8 9.3 17.9 5.9 4.1 41.8 6.0 14.2 1.2 6.5 6.5 3.4 5.4 6.2 10.2 4.7 4.5 3.7 2.0 2.6 5.2 3.3 1.6 6.4 4.8 4.4 6.8 7.3 8.0 2.2 0.7 3.2 8.1 2.8 3.2 2.4 7.6 5.4 2.7 2.8 1.3 2.3 8.3 43.4 1.2 3.7 5.1 11.8 12.1 11.8 18.4 4.9 7.6 2.5 2.7 5.3 7.6 2.5 2.3 16.3 2.8 2.5 5.7 6.7 2.6 5.4 2.6 2.4 2.0 2.7 3.2 3.4 2.6 1.6 2.3 2.3 5.6 1.9 2.1 0.4 3.6 2.3 25.0 26.4 21.0 20.7 24.6 38.7 24.6 35.0 25.1 27.4 31.4 28.4 6.9 16.0 11.9 52.2 2.4 3.1 12.6 6.6 7.4 6.4 27.1 14.4 14.5 4.3 13.4 11.0 6.2 26.4 3.1 3.9 11.7 10.1 200.0 8.3 9.2 5.4 2.4 1.7 45.0 10.6 14.0 42.5 5.6 3.7 4.5 4.2 3.9 1.9 6.4 1.7 32.4 2.4 16.2 3.5 4.7 32.1 15.5 5.0 12.4 24.4 5.6 14.9 7.2 50.3 43.3 10.3 2.0 11.7 4.6 16.7 0.8 5.0 17.7 5.2 6.6 9.4 16.8 46.0 5.0 16.0 4.4 29.0 3.6 3.9 2.3 21.7 CACNA2D2 KIAA0558 ENSG00000007402 "Calcium voltage-gated channel auxiliary subunit alpha2delta 2" Q9NY47 3 50362613-50504244 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 49.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Alveolar cells type 2: 182.3;Inhibitory neurons: 36.0" "Cancer enhanced" "Detected in many" "testis cancer: 20.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 8 "SH-SY5Y: 192.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034771, HPA071829" Enhanced Approved Vesicles NA NA 9700000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA034771: AB_10603555, HPA071829: AB_2686454" "unprognostic (2.06e-1)" "unprognostic (2.37e-1)" "unprognostic (1.72e-2)" "prognostic unfavorable (7.62e-5)" "unprognostic (6.59e-2)" "unprognostic (6.37e-2)" "unprognostic (6.91e-2)" "unprognostic (6.57e-3)" "unprognostic (4.39e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.21e-4)" "unprognostic (2.71e-2)" "unprognostic (1.57e-4)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (3.55e-1)" "unprognostic (4.22e-2)" 1.0 0.6 4.7 1.3 5.2 1.2 1.2 9.9 6.9 1.4 0.3 1.6 1.2 1.6 0.9 0.6 1.1 0.7 8.4 0.7 13.9 2.3 0.3 49.1 1.2 8.3 8.4 2.1 4.3 2.5 7.1 1.8 14.0 3.0 1.9 8.6 1.3 1.1 1.8 2.6 1.6 1.2 4.8 1.4 4.1 6.5 11.4 1.0 2.2 1.5 0.5 0.5 0.7 2.1 0.0 0.1 3.0 6.6 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.6 0.0 0.6 0.2 24.8 0.0 0.1 0.1 1.8 0.2 0.2 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.4 0.0 1.1 0.1 0.2 7.9 0.2 0.5 0.2 0.0 0.7 0.0 0.0 18.6 192.7 0.6 0.4 0.0 5.5 1.5 0.0 0.0 0.1 1.8 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.9 0.7 0.9 0.7 0.0 0.5 1.2 0.7 0.0 0.9 0.0 0.1 1.2 0.4 4.7 5.2 9.9 6.9 0.7 13.9 8.3 8.4 14.0 4.8 11.4 2.1 0.4 76.9 182.3 4.2 0.4 1.5 0.4 0.0 1.8 21.5 2.5 1.7 4.6 0.0 2.5 1.8 20.9 0.0 6.8 0.8 0.0 0.2 0.7 0.1 0.4 0.6 1.2 2.7 7.8 0.0 0.0 1.5 3.1 0.2 20.3 0.3 0.4 0.0 0.1 0.0 36.0 11.0 0.0 0.0 0.4 4.0 0.3 0.4 0.0 1.9 0.1 4.3 15.5 6.0 0.9 0.4 0.3 1.9 2.9 0.7 0.2 0.7 2.2 9.8 13.1 2.4 2.4 2.6 11.2 0.2 0.6 0.3 2.9 3.4 0.6 0.3 CACNG4 "MGC11138, MGC24983" ENSG00000075461 "Calcium voltage-gated channel auxiliary subunit gamma 4" Q9UBN1 17 66964707-67033398 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 35.1;prostate: 11.7" "Cell type enriched" "Detected in some" 6 "Oligodendrocyte precursor cells: 145.3" "Group enriched" "Detected in many" 5 "breast cancer: 30.3;glioma: 35.8;ovarian cancer: 14.8;prostate cancer: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 6 "SH-SY5Y: 387.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 118.1" "HPA005803, HPA065370" Enhanced Approved Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA005803: AB_2667439, HPA065370: AB_2685480" "unprognostic (1.27e-1)" "unprognostic (3.16e-1)" "unprognostic (8.87e-2)" "unprognostic (1.05e-2)" "unprognostic (6.42e-2)" "unprognostic (8.64e-3)" "unprognostic (2.91e-1)" "unprognostic (7.08e-2)" "unprognostic (3.37e-2)" "unprognostic (3.85e-2)" "unprognostic (6.03e-2)" "unprognostic (3.87e-2)" "unprognostic (2.38e-10)" "unprognostic (8.57e-3)" "unprognostic (1.23e-1)" "unprognostic (8.71e-2)" "unprognostic (4.28e-1)" 0.5 0.8 26.5 0.1 35.1 0.0 5.3 6.9 26.8 0.4 4.2 0.8 0.2 0.5 0.1 0.2 4.2 0.4 0.2 14.5 17.9 0.2 0.0 5.7 0.0 11.7 16.7 0.1 0.4 1.2 0.3 0.7 15.0 11.7 0.1 0.7 1.7 1.3 0.1 0.5 0.1 1.1 14.3 0.0 1.5 0.2 29.6 0.0 0.1 0.0 0.0 0.4 0.7 9.5 6.4 4.1 15.6 0.0 0.0 0.0 4.4 0.0 0.0 1.4 0.0 4.6 0.2 0.0 0.2 0.0 41.2 64.1 0.1 0.0 0.0 0.0 0.3 0.0 1.8 3.7 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 34.5 0.1 0.3 15.7 7.3 0.0 0.0 0.4 8.7 0.0 11.1 15.8 387.4 3.6 10.4 0.0 38.1 38.5 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.5 35.1 6.9 26.8 14.5 17.9 11.7 16.7 15.0 14.3 29.6 9.5 0.0 3.2 1.3 0.0 0.0 0.0 1.1 0.3 0.0 0.2 6.4 3.4 1.3 0.0 1.4 0.0 0.0 0.3 0.1 0.6 0.0 0.1 2.6 1.0 0.2 0.1 7.7 0.0 1.8 0.2 0.2 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.7 0.0 3.4 0.0 145.3 0.3 0.7 0.2 0.0 0.0 2.6 0.0 0.0 1.9 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.7 CADPS "CAPS, CAPS1, KIAA1121, UNC-31" ENSG00000163618 "Calcium dependent secretion activator" Q9ULU8 3 62398346-62875416 "Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.6;retina: 184.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 772.6;Cone photoreceptor cells: 627.6;Excitatory neurons: 830.8;Inhibitory neurons: 1152.7;Oligodendrocyte precursor cells: 266.9" "Cancer enhanced" "Detected in many" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 11.5;SCLC-21H: 19.7;SK-MEL-30: 9.0;U-698: 13.2;U-87 MG: 20.5" HPA059328 Enhanced Supported Approved Vesicles NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA059328: AB_2683982" "unprognostic (3.46e-3)" "unprognostic (1.40e-2)" "unprognostic (1.61e-2)" "unprognostic (3.87e-2)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "unprognostic (2.21e-1)" "unprognostic (3.12e-2)" "unprognostic (9.27e-2)" "unprognostic (5.73e-2)" "unprognostic (2.08e-3)" "unprognostic (3.21e-1)" "unprognostic (4.20e-3)" "unprognostic (1.90e-2)" "unprognostic (2.04e-1)" "unprognostic (7.91e-3)" "unprognostic (5.35e-3)" 0.4 16.4 32.2 2.0 47.7 0.1 0.7 18.7 84.6 2.8 0.0 2.8 3.2 0.6 2.5 0.2 0.4 2.4 16.7 32.1 26.0 0.2 0.2 0.8 0.5 83.2 39.7 1.9 13.5 0.2 39.6 0.2 84.5 3.6 2.4 184.3 1.4 2.8 0.1 1.4 3.3 0.8 4.1 0.6 3.0 3.2 33.0 0.6 0.2 0.0 0.7 0.4 1.4 61.7 0.0 0.0 0.8 0.0 4.2 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.5 11.5 0.0 0.1 0.0 0.0 0.0 0.0 19.7 1.5 0.0 0.0 9.0 0.4 0.0 0.0 0.1 1.6 0.1 3.3 0.9 0.0 1.7 13.2 20.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 47.7 18.7 84.6 32.1 26.0 83.2 39.7 84.5 4.1 33.0 61.7 0.0 0.0 1.9 93.0 0.1 1.3 0.2 0.0 0.0 772.6 0.5 2.8 25.6 7.2 0.0 0.0 627.6 0.1 0.0 0.4 0.0 4.1 1.1 0.2 1.1 0.9 95.9 0.0 830.8 0.4 0.0 3.2 0.0 0.1 42.5 0.2 0.0 0.0 0.0 47.1 1152.7 5.0 0.0 0.0 1.6 2.1 15.2 0.0 8.8 30.0 0.0 21.3 0.0 266.9 27.0 0.9 1.3 2.6 0.0 0.3 0.7 0.1 0.0 64.7 0.0 3.2 1.2 0.2 0.7 0.0 0.1 0.0 0.4 36.9 1.8 0.2 CALB1 CALB ENSG00000104327 "Calbindin 1" P05937 8 90058608-90095475 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 320.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 26.1;Collecting duct cells: 27.6;Cone photoreceptor cells: 91.8;Distal tubular cells: 31.3;Horizontal cells: 99.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.8" "Group enriched" "Detected in many" 6 "granulocytes: 2.8;monocytes: 1.4" "Cell line enhanced" "Detected in many" "A-431: 134.9;EFO-21: 189.8;HeLa: 65.9" "Region enhanced" "Detected in all" "cerebellum: 430.7" "Group enriched" "Detected in all" 4 "basal ganglia: 49.7;cerebellum: 119.6" "CAB002138, HPA023099, HPA056734" Enhanced Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Vesicles "CAB002138: AB_563448, HPA023099: AB_1845859, HPA056734: AB_2683220" "unprognostic (2.19e-1)" "unprognostic (2.28e-3)" "unprognostic (2.61e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.82e-1)" "unprognostic (5.39e-2)" "unprognostic (2.05e-1)" "unprognostic (1.27e-1)" "unprognostic (3.49e-2)" "unprognostic (1.37e-2)" "unprognostic (7.36e-2)" "unprognostic (1.59e-1)" "unprognostic (9.01e-2)" "unprognostic (2.11e-1)" "unprognostic (7.88e-2)" "unprognostic (2.24e-1)" "unprognostic (1.42e-1)" 2.4 1.6 7.4 2.0 31.3 1.3 1.7 63.0 21.1 5.5 0.0 1.7 3.2 1.2 3.4 8.5 1.9 1.4 0.9 9.2 14.0 320.6 2.6 3.6 0.9 16.8 10.4 1.2 2.5 2.2 8.4 3.9 6.3 0.8 2.5 54.1 1.7 0.5 1.9 3.5 2.7 1.3 15.9 1.3 2.3 3.6 32.1 2.7 2.5 0.3 1.2 0.5 0.1 7.8 134.9 6.1 30.2 1.2 1.1 4.9 4.0 2.0 5.8 0.7 1.1 2.9 15.1 0.5 189.8 0.1 0.8 47.8 46.0 54.6 9.1 0.3 2.5 3.2 65.9 0.7 5.3 0.8 4.4 1.5 17.3 2.5 25.4 7.0 36.1 2.6 9.9 3.4 35.9 0.6 1.9 0.1 45.3 2.9 17.9 1.3 1.2 3.9 12.9 0.7 5.0 2.9 38.2 2.3 0.6 45.8 1.7 1.1 0.1 3.9 28.1 6.6 11.9 3.1 3.9 1.0 0.5 0.9 0.2 1.5 0.2 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 1.4 0.3 0.0 0.4 7.4 31.3 63.0 21.1 9.2 14.0 16.8 10.4 6.3 15.9 32.1 7.8 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 26.1 0.0 0.1 1.5 0.0 0.0 27.6 91.8 0.0 0.0 0.0 31.3 0.0 14.9 0.0 0.1 0.3 3.5 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 99.3 14.7 0.0 0.0 0.0 0.0 1.7 0.9 0.0 0.0 0.0 0.0 15.8 0.0 1.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 12.8 0.0 0.3 0.4 0.3 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 CAT ENSG00000121691 Catalase P04040 11 34438934-34472060 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrogen peroxide" "Mitogen, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1217.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 722.4;Hepatocytes: 443.4;Proximal tubular cells: 333.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 13 "eosinophil: 4736.8" "Lineage enriched" "Detected in all" 13 "granulocytes: 4736.8" "Cell line enhanced" "Detected in many" "HL-60: 391.4;THP-1: 321.2;U-937: 265.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001515, HPA051282, HPA055838" Enhanced Enhanced Vesicles NA NA 760000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "CAB001515: AB_384710, HPA051282: AB_2681419, HPA055838: AB_2682937" "unprognostic (3.62e-2)" "unprognostic (2.72e-1)" "unprognostic (3.59e-3)" "unprognostic (5.43e-2)" "unprognostic (4.44e-2)" "unprognostic (5.80e-3)" "prognostic favorable (9.67e-4)" "unprognostic (9.95e-3)" "unprognostic (3.22e-1)" "unprognostic (7.23e-2)" "unprognostic (3.34e-2)" "unprognostic (9.77e-2)" "prognostic favorable (1.96e-8)" "unprognostic (1.01e-1)" "unprognostic (7.31e-2)" "unprognostic (4.77e-2)" "unprognostic (6.59e-3)" 281.3 115.1 27.1 52.1 29.6 407.7 123.6 27.9 35.5 82.0 39.4 82.6 145.1 53.1 34.8 40.1 86.8 59.8 58.1 26.6 29.4 296.6 1217.3 163.2 58.4 35.2 29.4 46.7 86.3 43.2 13.6 78.0 34.3 66.8 71.3 9.8 83.7 64.0 103.8 70.6 136.3 59.4 29.6 78.6 74.1 11.4 29.5 74.9 122.6 136.6 56.7 105.8 39.9 40.8 31.7 34.3 24.5 38.9 233.2 100.6 52.3 39.3 49.8 43.3 47.1 19.7 30.9 78.3 37.5 79.2 63.9 73.9 42.3 42.9 47.3 68.8 38.8 65.6 34.0 113.7 27.6 391.4 31.1 54.5 29.3 13.2 5.1 59.9 53.2 46.2 139.3 31.3 55.1 30.2 81.1 77.4 0.1 148.7 82.6 56.5 117.9 64.9 120.2 117.2 13.1 19.8 44.5 70.6 60.0 0.0 101.4 321.2 38.3 25.9 24.9 65.4 23.8 25.0 15.2 16.8 51.3 265.6 19.3 256.5 324.7 4736.8 54.4 265.1 64.6 133.9 63.7 61.0 353.5 124.1 61.7 66.7 290.2 105.7 298.5 235.8 92.7 397.9 27.1 29.6 27.9 35.5 26.6 29.4 35.2 29.4 34.3 29.6 29.5 40.8 196.9 227.6 275.9 41.1 53.8 28.9 93.7 44.9 27.9 13.5 42.6 36.1 44.9 82.9 66.9 73.5 27.1 96.8 92.0 59.4 225.0 36.0 2.7 72.2 41.4 43.8 48.0 722.4 12.6 26.2 30.0 53.1 54.6 29.3 24.0 38.7 57.1 443.4 138.5 0.0 1.2 56.9 91.6 125.5 95.8 6.2 78.3 93.9 26.6 16.9 253.4 19.5 28.8 22.6 45.6 15.3 44.8 77.5 25.4 37.0 151.6 333.2 96.9 19.4 78.9 46.6 68.0 6.3 11.3 24.4 27.1 40.5 37.7 57.7 95.6 97.5 CATSPERB "C14orf161, FLJ14298" ENSG00000133962 "Cation channel sperm associated auxiliary subunit beta" Q9H7T0 14 91580696-91780707 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pancreas: 10.7" "Cell type enhanced" "Detected in some" "Early spermatids: 22.9;Exocrine glandular cells: 10.9;Gastric mucus-secreting cells: 11.7;Glandular and luminal cells: 6.2;Pancreatic endocrine cells: 7.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.2;OE19: 1.3;U-937: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA035134 Uncertain Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 32: U-937 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA035134: AB_10671510" "unprognostic (2.69e-2)" "unprognostic (1.95e-1)" "unprognostic (1.16e-3)" "unprognostic (1.93e-1)" "unprognostic (7.04e-3)" "unprognostic (2.72e-5)" "unprognostic (1.81e-1)" "unprognostic (5.01e-3)" "unprognostic (1.81e-3)" "unprognostic (3.52e-3)" "unprognostic (2.30e-2)" "unprognostic (4.34e-1)" "unprognostic (8.99e-3)" "unprognostic (6.85e-2)" "unprognostic (8.31e-2)" "unprognostic (8.88e-2)" "unprognostic (2.71e-3)" 0.5 0.2 0.5 0.6 0.5 0.3 0.8 1.0 0.5 0.4 0.1 0.6 0.4 0.2 0.4 0.5 0.4 0.8 0.4 0.3 0.2 0.2 0.1 0.6 0.9 0.3 0.1 0.3 10.7 0.3 0.2 0.2 0.3 0.6 0.5 0.8 2.5 0.2 1.2 2.3 0.9 0.2 0.1 0.6 1.4 1.1 0.2 0.3 0.5 0.0 0.5 0.2 0.2 0.8 0.2 0.0 0.2 0.5 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.7 1.2 0.4 0.3 0.0 0.0 0.2 0.0 0.1 0.2 0.4 0.6 0.1 0.4 0.7 0.0 0.5 0.2 0.1 0.2 0.1 0.1 0.5 0.0 0.3 0.1 0.0 0.1 0.7 0.2 0.2 0.0 1.3 0.1 0.1 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.2 0.5 0.5 0.1 0.7 0.3 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.0 1.2 0.3 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.5 1.0 0.5 0.3 0.2 0.3 0.1 0.3 0.1 0.2 0.8 0.1 3.2 1.5 0.3 0.1 0.1 0.3 0.2 0.0 0.0 3.3 1.0 0.2 0.0 2.1 0.0 0.0 0.1 0.3 2.2 0.0 2.7 22.9 1.6 0.9 0.6 0.0 0.0 4.9 10.9 0.1 0.6 11.7 6.2 0.0 0.1 0.0 0.1 0.0 0.0 1.3 3.0 0.0 0.3 0.3 3.2 0.6 0.1 0.0 1.9 0.6 0.0 1.0 0.5 1.8 7.5 2.5 0.0 0.4 0.9 0.1 0.5 1.5 0.0 0.0 0.9 0.3 4.5 0.2 0.8 0.0 0.3 0.7 0.1 1.4 0.8 CAV2 CAV ENSG00000105971 "Caveolin 2" P51636 7 116287380-116508541 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 227.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 887.8;Basal keratinocytes: 484.0;Pancreatic endocrine cells: 447.4;Prostatic glandular cells: 428.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 114 "basophil: 97.0" "Lineage enriched" "Detected in single" 399 "granulocytes: 97.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 274.1;HBEC3-KT: 329.8;LHCN-M2: 341.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013488, HPA044810" Enhanced Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB013488: AB_2533493, HPA044810: AB_2679098" "unprognostic (4.76e-2)" "unprognostic (3.91e-3)" "unprognostic (4.56e-2)" "unprognostic (2.91e-1)" "unprognostic (5.09e-3)" "prognostic unfavorable (5.80e-5)" "unprognostic (3.66e-2)" "unprognostic (2.27e-2)" "unprognostic (3.81e-1)" "unprognostic (3.34e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (6.32e-2)" "unprognostic (3.44e-3)" "unprognostic (7.84e-3)" "unprognostic (2.88e-1)" "unprognostic (2.42e-1)" "unprognostic (6.34e-3)" 227.4 9.9 8.8 18.7 10.0 0.9 75.6 9.1 13.0 64.2 6.5 41.4 11.3 35.8 23.1 43.6 30.3 72.2 153.0 9.1 8.6 17.1 41.4 161.3 8.8 10.4 9.1 36.2 28.2 5.9 5.9 93.2 10.2 32.0 16.5 16.9 24.5 32.4 23.4 47.6 17.5 42.8 10.1 52.3 19.8 15.6 10.9 9.4 108.4 37.8 7.3 45.0 36.8 10.9 230.3 61.7 2.9 0.6 103.9 111.5 4.9 157.7 184.4 51.9 45.9 11.8 274.1 0.2 181.9 165.7 160.9 217.4 2.9 329.8 72.9 0.6 16.9 2.1 45.6 0.1 64.4 0.4 1.1 66.7 185.1 70.4 143.5 84.1 173.5 0.1 11.8 8.9 341.1 13.1 0.1 0.3 3.0 7.6 41.7 2.6 76.0 3.1 190.1 7.0 0.3 0.2 120.5 4.3 30.1 32.4 0.4 1.6 240.9 0.5 31.6 101.3 52.6 9.7 0.6 0.8 20.8 0.2 111.4 97.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.8 0.1 0.0 0.2 0.0 0.5 8.8 10.0 9.1 13.0 9.1 8.6 10.4 9.1 10.2 10.1 10.9 10.9 313.9 887.8 89.0 0.3 2.0 484.0 306.6 341.8 121.8 4.8 27.1 65.7 223.9 164.5 207.3 40.5 4.2 15.3 2.1 1.9 35.2 279.1 25.7 5.1 27.6 235.5 1.8 4.0 1.9 100.1 128.2 66.2 2.0 9.8 2.5 9.8 144.2 42.4 4.9 0.0 1.1 12.9 107.8 6.1 48.6 18.2 94.4 5.4 145.9 12.2 2.1 223.3 0.0 5.5 1.0 447.4 1.4 194.1 3.5 428.5 7.9 4.3 48.8 8.0 190.7 44.4 198.9 4.8 1.5 45.4 282.0 12.4 5.9 199.6 4.8 202.5 CCDC130 MGC10471 ENSG00000104957 "Coiled-coil domain containing 130" P13994 19 13731760-13763296 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056977 Approved Approved Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA056977: AB_2683297" "unprognostic (6.54e-2)" "unprognostic (5.72e-3)" "unprognostic (2.13e-3)" "unprognostic (1.27e-3)" "unprognostic (2.71e-1)" "prognostic favorable (7.83e-5)" "unprognostic (7.04e-2)" "unprognostic (1.25e-2)" "unprognostic (2.47e-1)" "unprognostic (9.69e-2)" "prognostic favorable (2.34e-4)" "unprognostic (2.06e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (1.94e-1)" "prognostic favorable (1.82e-4)" 24.4 20.9 17.3 20.5 21.1 23.1 26.2 18.3 24.8 30.4 21.2 24.8 17.1 27.3 3.6 22.5 28.9 11.7 26.8 17.3 20.7 26.9 24.7 27.2 23.4 22.9 20.1 37.5 25.8 13.1 28.9 15.0 22.1 27.2 7.5 13.4 24.3 10.6 28.2 26.4 29.6 10.9 17.9 31.3 25.0 20.4 21.2 16.5 32.6 11.6 12.2 25.5 27.1 28.7 14.9 10.1 19.3 19.7 12.5 9.7 11.9 15.6 13.2 14.3 13.5 9.5 10.2 12.6 11.3 12.5 11.4 14.4 8.9 8.0 4.6 21.6 26.2 9.7 34.3 14.5 24.4 9.5 24.9 13.8 17.3 17.6 12.0 15.2 16.6 23.2 9.9 22.9 9.0 11.1 25.8 21.1 13.2 7.7 20.1 22.1 9.4 17.1 11.4 16.8 11.8 15.5 10.0 10.4 25.0 9.7 8.3 22.5 13.7 23.2 9.6 27.9 20.4 36.5 14.8 10.3 20.2 22.6 16.2 18.3 12.9 20.3 13.2 11.3 16.4 15.2 14.2 14.1 13.1 18.0 13.0 14.8 13.5 14.4 15.2 10.8 12.8 11.3 17.3 21.1 18.3 24.8 17.3 20.7 22.9 20.1 22.1 17.9 21.2 28.7 25.5 9.6 17.9 21.5 29.0 13.4 15.4 20.2 15.4 30.3 18.6 18.4 14.5 8.6 18.6 29.5 27.1 17.3 31.4 25.6 7.9 17.6 40.2 22.7 24.8 22.4 18.7 16.0 19.8 15.7 19.1 19.5 53.0 26.9 24.6 34.9 17.5 10.8 18.0 26.9 24.9 18.1 24.4 18.6 33.8 24.4 19.0 21.9 24.9 15.0 24.9 26.0 17.5 14.1 30.3 18.1 25.5 17.0 27.3 12.8 32.1 18.9 23.0 41.7 26.3 16.6 23.6 35.5 20.3 19.2 15.6 35.0 31.0 31.8 17.5 11.0 CCDC169-SOHLH2 C13orf38-SOHLH2 ENSG00000250709 "CCDC169-SOHLH2 readthrough" 13 36168794-36297842 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 22 "testis: 10.2" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Inhibitory neurons: 1.2;Late spermatids: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.3;HL-60: 2.6;NB-4: 1.5;U-937: 2.0" HPA029182 Uncertain Vesicles NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA029182: AB_10602409" "unprognostic (5.56e-2)" "unprognostic (3.93e-1)" "unprognostic (3.60e-2)" "unprognostic (4.66e-1)" "unprognostic (2.17e-1)" "unprognostic (1.84e-2)" "unprognostic (6.12e-2)" "unprognostic (3.43e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 10.2 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.4 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCDC190 "C1orf110, MGC48998" ENSG00000185860 "Coiled-coil domain containing 190" Q86UF4 1 162824458-162868815 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 2.3;choroid plexus: 1.0;esophagus: 3.3;lung: 1.8" "Cell type enriched" "Detected in some" 4 "Respiratory ciliated cells: 26.2" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 3.9;hTERT-RPE1: 4.8;HUVEC TERT2: 4.8;LHCN-M2: 7.3;TIME: 16.7;U-2197: 8.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028579, HPA028584, HPA028592" Uncertain Approved Vesicles NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA028579: AB_10610978, HPA028584: AB_10599423, HPA028592: AB_10601001" "unprognostic (4.29e-1)" "unprognostic (8.37e-2)" "unprognostic (1.75e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-2)" "unprognostic (8.33e-3)" "unprognostic (3.04e-2)" "unprognostic (3.09e-2)" "unprognostic (6.41e-2)" "unprognostic (7.41e-5)" "unprognostic (2.64e-1)" "unprognostic (1.52e-1)" "unprognostic (5.26e-1)" "unprognostic (1.70e-1)" 0.1 0.1 0.9 0.0 1.0 0.0 0.0 0.3 1.0 0.1 1.0 0.0 0.0 0.1 0.3 3.3 0.5 0.4 0.5 1.4 2.1 0.0 0.0 1.8 0.0 1.6 2.1 0.0 0.0 0.0 0.1 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.5 0.0 0.1 0.3 2.3 0.0 0.1 0.1 0.4 0.1 0.0 2.3 0.1 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.2 0.3 0.2 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 3.9 2.4 4.8 4.8 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.4 0.0 8.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 0.3 1.0 1.4 2.1 1.6 2.1 1.0 0.5 2.3 2.3 0.0 0.0 0.5 0.0 0.2 0.0 0.7 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 2.5 0.6 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 26.2 0.0 0.0 0.4 0.5 0.1 0.2 5.8 0.0 0.0 0.0 0.0 0.0 0.5 CCDC74A FLJ40345 ENSG00000163040 "Coiled-coil domain containing 74A" Q96AQ1 2 131527675-131533666 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 73.5" "Cell type enhanced" "Detected in many" "Early spermatids: 424.4;Late spermatids: 274.9;Respiratory ciliated cells: 166.1;Spermatocytes: 154.2;Theca cells: 211.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 28.6;SCLC-21H: 23.2" HPA060727 Uncertain Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA060727: " "prognostic favorable (5.11e-4)" "unprognostic (2.89e-3)" "unprognostic (6.49e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.91e-1)" "unprognostic (1.36e-2)" "unprognostic (2.18e-3)" "unprognostic (1.71e-1)" "unprognostic (2.40e-2)" "unprognostic (1.52e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (1.70e-7)" "unprognostic (7.28e-3)" "prognostic favorable (4.92e-4)" "unprognostic (5.96e-2)" "unprognostic (3.53e-2)" 3.3 32.7 10.6 1.2 9.6 0.1 9.6 7.3 11.3 17.6 29.3 6.9 1.1 12.8 8.9 3.0 34.5 7.0 3.5 11.1 12.2 8.9 1.2 6.2 1.3 12.1 12.8 14.8 2.6 20.4 34.7 1.1 10.5 15.8 1.7 2.0 3.1 6.3 0.5 4.9 2.5 3.0 10.5 1.2 3.2 73.5 15.1 5.3 7.3 0.8 0.8 14.5 8.0 8.0 0.0 5.9 6.0 0.3 8.4 20.2 0.5 5.1 8.4 4.6 3.4 0.2 8.9 2.3 3.1 7.9 7.7 4.6 2.6 1.5 1.9 6.1 11.1 0.0 6.2 0.2 1.0 0.2 0.5 6.6 0.6 4.5 0.0 9.0 1.8 12.7 3.4 6.5 4.2 3.8 13.3 3.6 28.6 2.3 3.8 6.4 0.0 2.7 11.8 0.1 23.2 16.9 0.6 0.8 0.9 2.3 8.2 1.3 1.9 1.4 4.3 18.0 3.9 1.3 1.2 0.8 19.0 0.6 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 9.6 7.3 11.3 11.1 12.2 12.1 12.8 10.5 10.5 15.1 8.0 0.8 0.0 0.5 1.6 0.3 5.1 12.2 21.6 14.2 1.0 34.8 28.4 0.5 4.3 15.8 7.3 0.0 0.5 1.1 0.8 7.9 9.4 424.4 88.2 7.6 1.4 7.7 0.0 3.7 0.7 0.4 11.1 1.1 4.7 0.0 30.4 1.4 0.1 0.3 0.0 2.4 0.6 16.2 0.0 5.9 274.9 37.0 0.8 1.8 1.0 0.0 14.2 0.0 1.0 0.5 2.7 0.5 68.4 0.9 7.4 0.1 2.6 166.1 1.1 0.0 2.5 14.2 154.2 18.8 7.2 6.0 0.3 1.2 211.1 2.4 7.2 CCDC74B DKFZp434E2321 ENSG00000152076 "Coiled-coil domain containing 74B" Q96LY2 2 130139287-130145134 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 55.4" "Cell type enhanced" "Detected in many" "Early spermatids: 322.3;Late spermatids: 129.6;Respiratory ciliated cells: 70.3;Spermatocytes: 142.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 10.2;SH-SY5Y: 14.8" HPA060727 Uncertain Vesicles NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA060727: " "prognostic favorable (4.46e-4)" "unprognostic (4.75e-3)" "unprognostic (2.67e-1)" "unprognostic (2.76e-3)" "unprognostic (2.81e-1)" "unprognostic (1.73e-1)" "unprognostic (8.69e-3)" "unprognostic (9.43e-2)" "unprognostic (2.99e-1)" "unprognostic (2.10e-1)" "unprognostic (6.43e-3)" "unprognostic (7.74e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (2.43e-2)" "unprognostic (1.48e-4)" "unprognostic (8.31e-3)" "unprognostic (9.94e-3)" 1.5 1.9 3.5 0.3 3.6 0.0 2.4 2.6 4.3 17.0 7.6 1.6 0.2 8.9 0.8 0.4 14.1 1.4 1.5 4.1 5.4 3.8 0.1 2.8 0.3 6.2 7.2 5.0 0.8 11.1 19.7 0.2 5.1 7.1 0.1 0.6 0.6 2.8 0.2 1.0 0.7 1.2 5.7 0.4 1.5 55.4 6.1 0.6 7.0 0.0 0.2 2.4 3.6 3.9 0.0 1.9 2.8 0.1 2.5 5.4 0.6 2.2 1.1 0.3 0.5 0.9 0.7 0.1 3.5 2.0 3.2 1.0 0.2 0.3 0.4 2.0 5.5 0.0 7.0 0.1 0.3 0.1 0.2 1.1 0.0 0.9 0.0 3.4 0.1 1.3 0.1 1.7 0.8 2.1 0.0 0.0 5.7 0.5 5.9 4.6 0.0 3.2 1.7 0.0 10.2 14.8 1.6 0.1 0.2 0.6 5.9 0.7 0.4 1.1 4.8 5.9 0.5 0.1 0.3 0.0 6.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.6 2.6 4.3 4.1 5.4 6.2 7.2 5.1 5.7 6.1 3.9 0.2 3.2 0.5 1.6 0.1 0.5 3.0 6.3 1.2 0.5 6.1 9.5 0.4 1.5 4.3 5.5 0.0 0.2 0.2 0.1 3.9 1.5 322.3 42.8 9.9 0.2 11.4 0.0 1.6 0.2 0.8 3.6 0.0 2.2 0.0 7.8 0.0 0.0 0.3 3.3 1.1 0.1 2.0 0.0 0.2 129.6 10.2 0.6 0.0 1.0 0.0 6.2 0.0 0.5 0.3 0.0 0.1 12.4 0.1 3.9 0.0 1.2 70.3 0.1 0.0 0.9 3.2 142.7 16.4 0.7 1.1 0.1 0.3 28.8 0.1 0.7 CCN3 "IGFBP9, NOV" ENSG00000136999 "Cellular communication network factor 3" P48745 8 119416446-119424434 "Plasma proteins, Predicted secreted proteins, Transporters" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 44 "adrenal gland: 1105.4" "Cell type enhanced" "Detected in some" "Adipocytes: 25.2;Endothelial cells: 2.7;Fibroblasts: 9.8;Smooth muscle cells: 4.6" "Cancer enriched" "Detected in all" 4 "melanoma: 62.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 116 "eosinophil: 64.8;neutrophil: 30.8" "Lineage enriched" "Detected in single" 157 "granulocytes: 64.8" "Cell line enhanced" "Detected in many" "BJ hTERT+: 125.0;hTERT-RPE1: 38.1;U-2197: 128.2" "Group enriched" "Detected in all" 6 "amygdala: 129.2;basal ganglia: 51.5;cerebral cortex: 99.5;hippocampal formation: 152.5;white matter: 85.0" "Region enriched" "Detected in all" 6 "spinal cord: 114.6" "HPA018449, HPA019684, CAB034423" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 269000000 2800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB034423: AB_2151387, HPA018449: AB_1846189, HPA019684: AB_1846190" "unprognostic (5.04e-2)" "unprognostic (1.01e-1)" "unprognostic (7.36e-3)" "unprognostic (1.30e-3)" "unprognostic (9.35e-3)" "unprognostic (4.92e-1)" "unprognostic (8.10e-2)" "unprognostic (6.04e-2)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.67e-1)" "unprognostic (3.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.74e-3)" "unprognostic (1.51e-1)" "unprognostic (1.98e-1)" "unprognostic (2.72e-2)" 23.7 1105.4 7.6 3.6 11.5 1.7 8.1 6.7 12.2 11.2 5.9 6.9 3.9 8.6 6.3 5.5 9.0 6.3 18.1 16.2 9.7 6.9 1.1 6.8 2.2 5.6 6.5 3.1 6.8 9.4 21.8 0.6 4.9 22.8 7.0 1.2 2.7 20.0 4.7 13.8 4.4 8.4 8.7 1.5 4.9 3.6 6.3 1.0 25.3 7.2 1.9 4.4 8.0 6.2 0.1 3.1 1.7 0.0 11.1 2.9 0.1 16.9 125.0 14.9 8.6 0.0 0.3 0.0 12.9 21.2 11.6 10.5 0.6 0.0 5.1 0.0 0.3 0.0 9.1 0.0 0.4 0.0 0.0 0.6 0.1 5.7 0.6 38.1 0.4 0.0 0.0 0.0 0.8 0.7 0.0 0.1 0.2 1.2 24.9 0.1 0.0 0.0 15.8 0.1 3.9 0.1 6.3 0.1 24.2 0.0 0.0 0.0 0.0 10.6 15.8 128.2 3.5 0.0 0.0 0.0 16.7 5.4 12.5 0.0 0.3 64.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 30.8 0.0 0.0 0.0 0.0 0.1 7.6 11.5 6.7 12.2 16.2 9.7 5.6 6.5 4.9 8.7 6.3 6.2 25.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CCZ1 "C7orf28A, CCZ1A, CGI-43" ENSG00000122674 "CCZ1 homolog, vacuolar protein trafficking and biogenesis associated" P86791 7 5898725-5926550 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045114, HPA050006" Uncertain Enhanced Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA045114: AB_2679219, HPA050006: AB_2680989" "unprognostic (1.91e-1)" "unprognostic (2.97e-3)" "unprognostic (3.15e-2)" "unprognostic (1.25e-2)" "unprognostic (1.82e-1)" "unprognostic (5.35e-2)" "unprognostic (3.74e-3)" "unprognostic (4.10e-1)" "unprognostic (9.25e-3)" "unprognostic (7.66e-2)" "unprognostic (6.64e-2)" "unprognostic (2.67e-2)" "unprognostic (5.27e-3)" "unprognostic (3.25e-1)" "unprognostic (1.31e-1)" "unprognostic (1.74e-1)" "unprognostic (4.41e-1)" 32.5 55.8 10.7 12.8 10.9 26.9 30.2 12.2 13.7 28.7 12.9 31.1 13.0 29.7 9.4 40.8 25.2 10.3 31.3 11.4 10.5 27.3 27.3 26.0 15.4 10.7 10.4 23.0 27.3 29.9 24.9 12.2 10.6 24.6 16.0 12.6 32.1 11.9 43.2 30.3 26.9 13.9 10.5 31.5 29.0 22.1 11.0 20.5 25.5 13.0 16.2 31.7 28.9 11.6 52.2 29.8 30.3 27.1 41.8 35.4 15.3 15.6 30.1 23.1 25.0 9.1 27.2 42.8 4.8 40.8 61.9 27.8 16.6 26.7 26.5 16.2 37.3 18.1 30.2 16.8 38.0 13.1 7.1 40.5 42.4 15.6 19.5 42.5 57.2 25.4 52.4 29.7 38.8 26.9 16.8 56.9 39.5 26.4 28.3 36.0 13.8 28.9 21.1 38.3 23.9 31.9 15.3 36.6 13.6 57.9 26.1 21.0 27.7 28.8 57.4 18.7 25.7 13.6 24.6 58.0 9.6 30.8 41.6 3.1 1.9 2.7 1.8 2.3 1.4 1.3 2.2 2.2 1.8 1.3 1.5 1.6 3.4 3.0 2.4 1.8 4.6 0.7 10.7 10.9 12.2 13.7 11.4 10.5 10.7 10.4 10.6 10.5 11.0 11.6 30.7 3.2 23.5 15.7 26.3 45.2 30.6 21.2 9.6 59.2 29.5 20.2 11.0 24.3 24.0 31.3 62.6 45.0 47.2 38.0 31.3 61.0 6.5 18.7 18.1 35.0 29.9 26.7 20.2 71.4 35.9 26.7 11.2 21.3 15.8 21.1 76.4 17.6 35.7 23.5 20.5 30.8 50.8 39.0 61.6 4.9 37.9 27.5 46.2 8.4 80.8 41.5 72.1 15.6 28.7 74.0 30.1 36.1 14.3 26.2 40.2 21.9 32.9 69.2 78.9 19.4 32.0 40.6 34.5 11.0 54.1 34.9 32.8 38.2 34.4 33.7 CCZ1B "C7orf28B, DKFZP586I1023, H_NH0577018.2, MGC19819" ENSG00000146574 "CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated" P86790 7 6794134-6826770 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA045114, HPA050006" Uncertain Enhanced Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 32: U-937 - Innate immune response" "Cluster 59: Non-specific - Transcription" Vesicles "HPA045114: AB_2679219, HPA050006: AB_2680989" "unprognostic (8.06e-3)" "unprognostic (1.53e-1)" "unprognostic (2.94e-2)" "unprognostic (1.00e-1)" "unprognostic (4.94e-2)" "unprognostic (1.45e-2)" "unprognostic (1.88e-3)" "unprognostic (2.74e-1)" "unprognostic (9.14e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (2.86e-1)" "unprognostic (2.96e-3)" "unprognostic (9.61e-2)" "unprognostic (1.27e-1)" "unprognostic (2.73e-2)" "unprognostic (1.24e-1)" 28.9 40.3 19.6 25.1 20.0 37.1 28.8 20.6 26.2 18.5 22.4 31.3 27.5 28.5 40.3 42.5 25.6 28.4 28.6 19.5 20.3 28.8 24.1 23.5 38.0 19.8 19.6 18.2 21.1 73.1 9.1 26.7 19.8 20.8 27.2 32.4 32.9 19.0 35.8 30.2 22.0 22.5 20.7 25.4 30.8 23.5 20.5 38.8 24.6 53.5 35.5 39.4 9.3 21.6 120.6 31.6 66.8 138.5 49.7 51.5 67.2 64.1 69.4 58.1 61.4 32.4 65.7 52.2 57.0 72.0 132.5 68.7 87.9 60.5 62.4 31.1 51.8 33.6 40.7 72.0 54.3 165.4 104.1 37.9 37.6 51.1 30.2 40.0 57.9 108.6 63.5 49.2 62.6 124.7 84.2 81.5 171.2 78.2 66.7 67.3 123.1 59.4 41.8 66.4 87.1 161.5 62.4 117.6 78.8 65.9 94.0 185.0 71.1 27.7 93.7 78.2 116.5 52.9 104.8 45.6 53.9 176.4 120.9 21.8 5.5 10.2 5.3 8.0 6.3 6.1 6.7 7.8 8.3 5.1 4.5 5.8 4.6 10.6 15.5 6.3 15.7 3.4 19.6 20.0 20.6 26.2 19.5 20.3 19.8 19.6 19.8 20.7 20.5 21.6 9.5 6.4 12.7 11.1 17.4 8.4 7.8 8.6 8.0 10.4 10.9 10.0 7.3 2.8 10.7 3.7 14.6 8.0 12.9 18.7 15.6 20.1 3.7 16.0 11.1 8.9 18.6 9.0 19.6 28.1 11.7 9.2 9.2 10.3 2.5 6.6 15.7 7.1 9.8 16.8 19.0 17.5 6.1 11.1 22.8 2.2 7.2 11.2 14.2 8.4 24.7 11.5 17.5 14.6 23.6 24.8 11.9 10.5 7.6 9.6 7.1 12.4 23.7 11.4 19.7 8.1 9.0 12.0 8.9 11.0 12.5 7.9 11.1 5.7 15.3 11.9 CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633701 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 403.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3697.0" "Group enriched" "Detected in all" 5 "granulocytes: 942.3;monocytes: 3697.0" "Cell line enhanced" "Detected in many" "A549: 10.1;CACO-2: 17.0;SiHa: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" NA NA 2750000000 10000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" 134.5 151.3 15.9 236.1 16.0 68.8 50.5 14.7 33.1 27.9 26.8 55.9 31.4 23.5 21.0 23.9 40.5 79.8 35.6 14.5 23.2 41.6 403.4 91.6 107.9 33.6 26.4 21.4 27.0 16.7 35.5 183.0 29.6 18.3 47.6 4.0 121.8 30.4 10.6 13.5 38.0 111.7 25.4 87.6 33.9 26.6 30.3 20.9 23.0 17.5 23.0 102.5 12.6 42.1 0.1 10.1 0.1 0.8 1.3 0.3 0.5 0.9 4.7 1.9 2.1 17.0 3.1 0.4 1.0 5.9 1.4 4.9 0.0 2.6 0.5 0.1 1.4 0.3 1.1 2.0 5.1 1.1 0.3 4.8 0.3 0.3 1.5 0.4 0.0 0.3 0.3 0.3 1.7 0.3 0.1 1.2 0.4 0.3 0.3 0.4 0.6 1.8 0.2 0.1 3.6 1.3 21.1 0.5 0.5 0.2 0.3 2.1 0.6 0.4 0.4 1.9 2.1 0.8 1.6 0.8 0.4 0.5 0.1 13.5 3697.0 21.7 6.8 677.3 8.7 12.1 3.7 3.9 440.4 1.9 5.2 3.6 942.3 3.8 95.1 25.2 3.7 3034.0 15.9 16.0 14.7 33.1 14.5 23.2 33.6 26.4 29.6 25.4 30.3 42.1 17.9 9.6 27.6 0.7 9.0 5.1 3.4 5.2 6.2 7.2 164.9 23.4 2.6 22.8 18.3 1.8 0.0 18.1 5.3 77.2 1.9 5.1 2.3 0.6 1.7 46.5 7.2 29.5 0.7 1.8 16.3 19.7 1.1 1.0 8.8 0.6 340.2 348.0 2809.2 33.7 0.9 5.9 4.1 668.4 75.9 6.1 5.0 652.8 8.8 23.4 285.3 30.0 11.3 0.5 0.4 1.8 35.3 5.3 1.8 1.7 5.0 7.0 9.8 5.1 32.9 25.8 9.7 1.5 2.0 4.4 4.3 46.1 5.5 2.1 7.4 4.9 CD24 CD24A ENSG00000272398 "CD24 molecule" P25063 6 106969831-106975627 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 1630.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1572.7;Distal tubular cells: 1590.6;Exocrine glandular cells: 3454.1;Glandular and luminal cells: 1441.8;Pancreatic endocrine cells: 1694.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 28 "eosinophil: 86.2;memory B-cell: 61.1;naive B-cell: 39.7" "Group enriched" "Detected in many" 237 "B-cells: 61.1;granulocytes: 86.2" "Cell line enhanced" "Detected in many" "NTERA-2: 989.4;RPTEC TERT1: 4702.6;RT4: 931.5;SK-BR-3: 1352.5" "HPA045879, CAB078471" Approved Enhanced Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "CAB078471: AB_10983158, HPA045879: AB_2732523" "prognostic unfavorable (2.44e-5)" "unprognostic (6.64e-2)" "prognostic favorable (3.29e-4)" "unprognostic (1.87e-1)" "unprognostic (1.41e-2)" "unprognostic (9.98e-2)" "prognostic unfavorable (7.58e-4)" "unprognostic (2.32e-1)" "unprognostic (2.74e-1)" "unprognostic (1.04e-1)" "unprognostic (2.28e-2)" "unprognostic (1.51e-1)" "unprognostic (5.10e-2)" "unprognostic (2.92e-1)" "unprognostic (1.16e-1)" "unprognostic (2.01e-1)" "unprognostic (3.13e-1)" 7.1 61.9 23.3 139.1 28.8 704.5 468.1 6.4 30.0 288.0 36.7 1071.8 89.0 181.5 229.6 1456.5 242.9 874.3 5.1 45.0 29.2 775.6 30.2 61.6 77.8 26.6 26.0 2.2 1383.4 2.5 12.5 151.7 17.2 148.8 740.8 2.6 952.4 546.9 1.4 77.2 69.8 117.7 19.5 29.6 601.7 4.9 38.6 15.2 1630.2 1.1 445.0 168.9 468.3 50.7 363.2 225.2 3.9 28.6 0.7 0.3 405.8 0.4 2.6 2.0 1.2 3.3 1.9 35.4 106.0 0.1 14.6 730.6 124.1 275.6 1.5 1.0 1.7 1.0 254.2 16.3 0.2 5.1 1.8 2.1 316.1 3.6 18.0 16.9 1.6 1.4 8.3 0.8 6.6 465.6 2.4 2.6 989.4 800.1 85.6 846.8 0.5 3.5 4702.6 931.5 612.4 448.7 250.0 1352.5 1.4 437.1 635.6 2.1 1.6 0.8 4.0 3.1 11.8 1.0 2.0 475.2 5.0 2.9 1.6 0.3 0.1 86.2 0.0 0.0 0.0 61.1 0.0 0.0 0.0 39.7 0.0 0.1 2.1 0.1 0.3 0.1 0.0 2.0 23.3 28.8 6.4 30.0 45.0 29.2 26.6 26.0 17.2 19.5 38.6 50.7 10.2 157.0 83.5 0.7 157.5 0.0 70.4 0.0 7.4 5.8 1109.4 325.4 1.5 1112.3 98.4 1302.1 2.1 749.2 13.7 1572.7 1590.6 1274.1 22.5 1237.6 254.2 38.6 575.4 5.3 0.6 3454.1 885.0 29.9 567.2 1441.8 10.8 0.6 97.5 9.7 70.8 0.0 5.7 463.6 0.0 7.6 0.0 53.4 10.2 17.6 0.0 1.0 32.6 1.0 0.0 0.0 0.1 1694.3 865.2 2.2 1.0 810.2 12.3 538.5 376.8 0.7 6.6 2.9 18.1 0.6 7.2 587.7 0.0 558.3 28.1 0.0 932.8 1043.7 CD276 "B7-H3, B7H3, B7RP-2" ENSG00000103855 "CD276 molecule" Q5ZPR3 15 73683966-73714514 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 215.6;Hofbauer cells: 82.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 175.0;U-2197: 231.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009285, HPA017139, CAB017826" Enhanced Approved Vesicles NA NA 16000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "CAB017826: , HPA009285: AB_1078258, HPA017139: AB_1845246" "unprognostic (1.05e-1)" "unprognostic (4.74e-3)" "unprognostic (4.57e-3)" "unprognostic (9.62e-2)" "unprognostic (1.26e-2)" "unprognostic (5.50e-3)" "prognostic unfavorable (9.81e-4)" "unprognostic (2.57e-3)" "unprognostic (1.89e-1)" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (3.29e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (1.17e-1)" "unprognostic (9.22e-2)" "unprognostic (1.21e-1)" "unprognostic (1.34e-3)" 24.1 19.1 6.6 12.9 4.3 0.7 15.3 0.4 6.5 22.2 15.6 11.4 11.0 20.2 4.3 5.8 10.0 18.2 14.8 4.2 5.7 5.4 11.8 11.6 3.6 5.9 6.7 13.4 15.3 4.3 6.1 26.2 4.1 16.7 4.2 4.6 15.0 9.6 5.0 16.2 8.4 10.8 2.4 9.0 10.9 6.0 7.5 1.6 8.5 2.2 1.6 14.6 13.0 6.7 43.7 44.6 32.5 82.8 57.7 35.0 102.8 47.5 42.0 33.4 30.4 85.3 90.1 0.6 77.7 39.5 64.1 175.0 31.7 39.9 4.4 30.6 76.3 2.8 47.6 47.1 20.9 0.7 51.8 32.7 17.9 28.3 15.4 19.7 38.7 0.0 15.0 0.8 6.2 66.0 0.3 2.3 84.9 8.6 35.9 0.5 47.9 7.0 27.9 53.8 24.9 59.5 40.1 21.2 88.0 23.0 38.1 26.4 49.8 68.6 60.0 231.6 52.5 0.9 0.8 0.8 114.8 3.4 49.4 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.1 0.0 0.0 6.6 4.3 0.4 6.5 4.2 5.7 5.9 6.7 4.1 2.4 7.5 6.7 4.4 19.2 8.1 6.5 1.2 15.0 11.5 12.5 8.0 20.2 14.1 11.8 9.1 2.8 17.0 11.0 31.3 11.6 0.2 6.7 1.9 48.6 0.9 14.4 26.7 22.0 9.0 0.0 18.4 19.0 215.6 43.7 14.3 31.6 14.7 41.4 4.6 14.6 82.5 10.1 12.9 13.1 4.1 8.8 30.8 2.2 9.9 14.7 24.9 7.5 4.2 8.4 0.0 5.5 1.7 24.7 15.1 17.3 1.7 12.1 3.1 2.7 5.8 27.5 13.1 7.0 32.1 1.8 4.9 3.4 10.2 12.3 1.4 8.4 10.6 8.4 CD63 "ME491, MLA1, TSPAN30" ENSG00000135404 "CD63 molecule" P08962 12 55725323-55729707 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1857.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 4897.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010088, CAB026356, HPA073506" Supported Supported Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB026356: AB_629864, HPA010088: AB_1846323, HPA073506: " "unprognostic (8.76e-3)" "unprognostic (8.81e-2)" "unprognostic (1.27e-1)" "unprognostic (1.28e-3)" "unprognostic (9.48e-2)" "unprognostic (3.66e-3)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.11e-1)" "unprognostic (6.50e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-2)" "unprognostic (3.10e-1)" "unprognostic (2.70e-2)" "unprognostic (4.82e-2)" "unprognostic (5.21e-2)" "unprognostic (1.85e-3)" "unprognostic (9.02e-2)" 954.0 882.1 509.4 457.9 526.5 747.2 769.6 532.6 717.1 715.6 611.8 809.3 394.5 854.6 1492.1 396.1 647.3 607.0 1152.2 508.5 565.7 625.3 565.1 882.2 325.0 564.7 539.9 645.9 830.1 524.7 486.6 588.0 544.3 520.0 736.0 269.1 871.6 547.4 919.3 410.0 559.3 744.5 534.9 597.7 790.8 224.3 583.6 193.3 657.7 587.4 284.9 835.3 539.7 561.7 481.0 669.0 432.6 430.8 4897.7 2932.4 577.5 1914.8 3104.6 979.2 1048.9 750.3 939.2 120.5 581.2 2608.7 787.7 436.3 301.7 732.6 1197.9 372.5 248.7 760.9 542.8 443.3 2006.7 338.5 1699.0 2315.1 639.7 1164.8 979.2 2305.1 1052.2 64.6 386.8 936.3 3062.5 626.3 64.1 439.5 395.7 1062.7 880.7 146.0 949.3 345.7 1699.3 1433.6 170.1 425.8 528.3 392.5 3348.6 630.4 546.4 1089.6 948.0 710.1 514.8 984.9 649.8 377.3 239.3 92.5 2023.9 208.1 1326.3 1279.9 610.3 1857.5 323.2 458.8 235.2 111.0 126.9 260.0 473.0 73.9 55.9 186.0 656.0 733.0 320.4 309.8 121.6 850.4 509.4 526.5 532.6 717.1 508.5 565.7 564.7 539.9 544.3 534.9 583.6 561.7 798.7 512.8 689.0 28.1 147.6 567.2 1382.5 3135.4 155.4 190.3 606.5 601.1 820.9 836.4 1789.7 875.4 152.2 608.3 322.0 1083.4 232.8 2621.2 16.7 446.7 766.7 916.3 581.1 97.0 8.8 3429.0 2756.5 1538.0 371.1 727.3 1030.0 531.6 739.6 423.9 3372.5 33.7 9.3 1251.6 1715.1 854.6 1698.3 65.5 1727.3 1146.7 1993.9 11.2 575.7 893.8 487.1 21.1 26.5 3437.4 1394.0 1157.0 326.9 2039.2 878.1 794.2 1012.6 258.8 1255.6 1845.2 1278.7 43.8 68.9 137.1 400.5 2708.1 310.4 645.8 761.6 1868.9 CD82 "IA4, KAI1, R2, ST6, TSPAN27" ENSG00000085117 "CD82 molecule" P27701 11 44564427-44620358 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 280.3;Proximal enterocytes: 220.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 536.4" "Group enriched" "Detected in all" 6 "B-cells: 310.1;granulocytes: 536.4;T-cells: 173.1" "Cell line enhanced" "Detected in many" "HMC-1: 463.8;U-87 MG: 323.3" "Region enhanced" "Detected in all" "white matter: 210.9" "Low region specificity" "Detected in all" "CAB002508, HPA028900, HPA061418" Supported Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB002508: AB_563640, HPA028900: AB_10603558, HPA061418: AB_2684510" "unprognostic (5.31e-2)" "unprognostic (4.62e-1)" "unprognostic (2.38e-2)" "unprognostic (1.33e-1)" "unprognostic (2.79e-1)" "unprognostic (1.37e-2)" "unprognostic (1.78e-1)" "unprognostic (7.29e-2)" "unprognostic (3.48e-1)" "unprognostic (2.97e-1)" "unprognostic (2.58e-2)" "unprognostic (1.58e-1)" "unprognostic (3.48e-3)" "unprognostic (1.86e-3)" "unprognostic (2.33e-2)" "unprognostic (2.88e-2)" "unprognostic (6.30e-2)" 39.2 9.1 47.7 57.3 80.5 140.9 36.6 45.2 48.8 38.8 48.5 24.7 74.1 9.1 31.9 130.9 54.0 39.6 25.6 41.9 51.7 26.1 36.9 87.3 68.5 58.5 74.3 14.9 31.3 7.8 7.5 41.0 49.8 27.5 17.2 4.2 81.1 72.1 23.1 84.2 81.6 16.6 39.6 47.3 62.8 4.5 79.0 45.0 22.4 20.0 82.6 47.6 66.1 67.2 30.0 5.2 35.1 7.2 24.0 98.4 1.2 16.9 132.9 29.4 78.5 2.0 19.6 30.9 20.8 8.1 61.1 118.8 4.6 88.4 59.6 145.4 2.7 220.9 9.3 0.6 21.3 58.8 463.8 142.1 99.2 128.3 62.1 68.4 49.7 26.9 1.6 9.4 247.3 25.0 46.7 97.7 1.1 103.2 2.4 1.5 190.0 43.9 16.8 36.1 1.2 2.0 13.0 162.6 23.0 4.2 161.2 51.3 33.9 94.4 12.5 1.8 179.0 3.6 0.4 0.9 323.3 32.5 56.0 369.9 59.3 110.7 29.9 33.0 51.4 310.1 150.7 70.3 14.9 211.9 51.1 23.1 536.4 50.1 25.0 44.5 173.1 65.9 47.7 80.5 45.2 48.8 41.9 51.7 58.5 74.3 49.8 39.6 79.0 67.2 43.6 48.1 38.8 9.4 112.8 55.1 108.1 149.0 107.6 2.4 68.1 54.7 7.7 58.6 143.8 158.2 2.1 1.3 14.9 17.4 11.7 79.7 2.0 23.1 5.0 41.0 13.2 92.9 0.3 66.7 1.1 29.1 58.6 25.2 280.3 0.7 59.6 32.5 64.3 1.7 0.6 36.8 63.1 26.6 18.2 2.0 40.4 52.3 64.0 3.7 11.0 35.7 0.0 54.3 22.4 86.7 50.3 8.2 16.0 59.1 220.6 2.5 73.0 2.7 13.1 109.0 46.0 2.1 5.9 161.3 67.2 1.4 46.3 0.6 43.1 142.8 CDH12 "Br-cadherin, CDHB" ENSG00000154162 "Cadherin 12" P55289 5 21750673-22853344 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.6;retina: 11.6" "Group enriched" "Detected in some" 15 "Excitatory neurons: 859.5;Inhibitory neurons: 887.7" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basal ganglia: 6.6;cerebral cortex: 3.8;hippocampal formation: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "PC-3: 2.2;SCLC-21H: 3.1;U-2 OS: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029325 Uncertain Uncertain Vesicles NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA029325: AB_2672998" "unprognostic (2.38e-1)" "unprognostic (3.21e-1)" "unprognostic (4.95e-2)" "unprognostic (8.61e-2)" "unprognostic (3.31e-2)" "unprognostic (3.91e-1)" "unprognostic (2.72e-1)" "unprognostic (3.26e-2)" "unprognostic (1.34e-1)" "unprognostic (3.51e-2)" "unprognostic (3.25e-4)" "unprognostic (7.35e-2)" "unprognostic (3.48e-2)" "unprognostic (5.19e-2)" 0.0 2.0 0.8 0.0 6.6 0.0 0.5 0.2 3.8 3.0 2.1 0.0 0.0 0.3 0.2 0.0 2.2 0.0 0.0 2.0 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 1.4 0.1 0.8 0.0 0.1 11.6 1.4 0.2 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 6.6 0.2 3.8 2.0 0.0 0.5 0.0 0.8 0.0 0.0 0.7 0.4 0.0 0.0 41.4 0.0 0.1 0.0 0.0 0.0 25.1 0.4 0.6 0.9 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.1 2.1 0.0 0.0 859.5 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.0 0.0 20.2 887.7 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 15.9 0.0 2.2 0.0 31.2 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.1 0.0 0.2 0.0 2.6 1.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 CEP295NL "DDC8, KIAA1731NL" ENSG00000178404 "CEP295 N-terminal like" Q96MC4 17 78870910-78903217 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 9.2;testis: 33.6" "Group enriched" "Detected in some" 133 "Early spermatids: 298.6;Late spermatids: 504.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.4;Karpas-707: 1.1;TIME: 1.2;U-2 OS: 1.9" "Not detected" "Not detected" "HPA023609, HPA024619, HPA025717" Uncertain Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA023609: AB_10610974, HPA024619: AB_10602076, HPA025717: AB_10601900" "unprognostic (1.68e-3)" "unprognostic (4.56e-2)" "unprognostic (2.62e-1)" "unprognostic (5.04e-3)" "unprognostic (1.88e-1)" "unprognostic (1.59e-1)" "unprognostic (1.89e-1)" "unprognostic (9.03e-2)" "unprognostic (8.16e-2)" "unprognostic (9.80e-2)" "unprognostic (2.08e-1)" "unprognostic (3.89e-3)" "unprognostic (3.65e-3)" "unprognostic (1.03e-1)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (6.75e-3)" 0.1 0.1 1.9 0.0 2.2 1.3 0.1 0.5 2.8 0.4 1.6 0.1 0.0 0.2 0.0 0.5 0.2 0.0 0.1 0.9 1.8 0.0 0.0 0.1 0.0 2.8 1.9 0.3 0.1 0.0 0.1 0.1 3.4 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 1.0 0.3 0.1 33.6 3.3 0.0 0.0 0.0 0.0 0.1 0.3 9.2 0.3 0.0 0.0 0.3 0.1 0.2 1.4 0.6 0.0 0.2 0.3 0.1 0.2 0.0 0.4 0.2 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.3 0.3 0.0 0.4 1.2 0.5 1.9 0.6 0.2 0.4 0.6 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 1.9 2.2 0.5 2.8 0.9 1.8 2.8 1.9 3.4 1.0 3.3 9.2 0.7 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 298.6 0.3 1.7 0.5 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.8 0.0 0.5 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 504.5 2.8 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 1.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 3.0 1.4 0.1 0.0 0.0 0.1 0.7 0.0 0.1 CERK "dA59H18.2, dA59H18.3, DKFZp434E0211, FLJ21430, FLJ23239, hCERK, KIAA1646, LK4" ENSG00000100422 "Ceramide kinase" Q8TCT0 22 46684410-46738252 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064699 Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA064699: AB_2685327" "unprognostic (2.93e-2)" "unprognostic (1.93e-1)" "unprognostic (6.52e-2)" "prognostic unfavorable (4.75e-4)" "unprognostic (2.67e-2)" "unprognostic (1.49e-3)" "unprognostic (8.55e-2)" "unprognostic (3.60e-2)" "unprognostic (3.87e-1)" "unprognostic (1.35e-2)" "prognostic favorable (2.35e-4)" "unprognostic (2.26e-1)" "unprognostic (1.50e-3)" "unprognostic (1.27e-1)" "unprognostic (4.78e-1)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.58e-4)" 15.7 23.7 17.5 22.2 18.1 21.1 12.7 33.2 22.5 17.8 16.4 17.9 31.6 17.5 6.0 14.8 18.2 17.4 39.0 18.3 37.4 19.5 18.9 16.6 26.1 32.1 34.5 26.6 30.2 11.5 49.0 10.0 33.2 11.7 14.9 21.1 17.5 13.4 20.8 16.3 31.2 15.2 20.8 19.4 21.9 6.0 26.2 38.7 21.0 19.2 25.2 13.7 12.4 18.4 25.6 15.1 71.6 22.6 40.3 30.2 6.7 43.7 33.8 24.5 17.2 22.3 8.4 35.3 19.9 46.9 15.1 16.3 30.4 19.8 24.9 12.6 33.0 15.8 36.9 29.0 27.9 49.9 4.0 25.3 25.0 26.7 9.1 39.2 73.5 37.1 12.1 44.5 45.4 1.9 34.0 24.8 32.4 10.3 16.3 62.8 81.2 40.4 14.7 0.5 66.4 60.6 21.5 10.3 47.1 16.5 11.3 37.6 67.4 50.2 26.8 37.5 64.4 45.7 59.5 22.3 53.5 28.0 41.7 0.7 3.0 3.7 10.3 7.0 17.9 2.0 10.7 10.0 5.4 2.1 6.3 5.8 4.2 2.6 8.7 5.7 10.4 4.4 17.5 18.1 33.2 22.5 18.3 37.4 32.1 34.5 33.2 20.8 26.2 18.4 28.6 9.6 16.6 16.0 17.0 3.4 6.3 6.1 18.2 24.4 6.1 9.8 44.2 10.0 11.0 1.8 6.2 2.4 25.4 23.4 15.6 12.8 7.8 10.3 19.8 27.4 14.4 8.0 11.7 11.8 1.4 14.1 9.2 19.8 10.1 10.2 25.4 22.1 10.8 26.9 21.9 6.6 8.2 24.8 16.9 16.0 9.6 22.1 3.6 15.9 18.6 25.6 22.6 9.5 4.2 10.9 15.2 15.1 43.3 2.1 50.0 16.8 0.7 9.7 0.0 8.3 13.2 4.7 1.7 11.0 4.4 1.8 37.6 5.3 20.0 1.7 CFH "ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS" ENSG00000000971 "Complement factor H" P08603 1 196652043-196747504 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Host-virus interaction, Immunity, Innate immunity" "Age-related macular degeneration, Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 1676.3" "Group enriched" "Detected in many" 4 "Fibroblasts: 448.0;Hepatocytes: 1114.8;Leydig cells: 283.9" "Cancer enriched" "Detected in all" 9 "liver cancer: 151.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 18.7" "Lineage enriched" "Detected in single" 26 "T-cells: 18.7" "Cell line enhanced" "Detected in many" "HHSteC: 123.1;HSkMC: 119.5;hTERT-RPE1: 374.9;RT4: 227.0" "CAB016385, CAB016769, HPA038922, HPA049176, HPA053326" Supported Approved Vesicles "Secreted to blood" NA NA 396000000000 100000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB016385: AB_627572, CAB016769: , HPA038922: AB_2676271, HPA049176: AB_2680663, HPA053326: AB_2682113" "unprognostic (2.40e-1)" "unprognostic (9.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.39e-2)" "unprognostic (5.40e-3)" "unprognostic (1.80e-1)" "unprognostic (3.75e-3)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (9.08e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (6.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" 125.3 42.1 18.1 32.7 21.5 1.3 66.9 20.0 29.6 76.8 43.0 51.0 30.5 12.8 15.9 63.8 24.2 133.6 301.5 18.1 18.6 25.5 1676.3 70.8 27.4 19.3 19.0 165.1 14.0 6.4 16.0 26.1 19.9 23.0 80.2 4.3 126.7 24.0 21.1 74.5 52.1 32.5 19.5 13.9 46.9 14.3 21.6 12.1 102.5 84.0 25.9 149.9 27.0 21.1 0.0 64.9 0.0 0.0 96.5 54.7 0.1 25.8 63.1 3.5 13.5 0.1 11.9 0.3 9.6 0.1 0.2 2.2 0.0 23.6 2.6 1.3 0.0 20.0 74.7 0.0 123.1 0.9 0.3 119.5 0.3 18.4 7.9 374.9 79.2 0.0 74.4 2.7 89.4 0.1 0.5 0.1 0.4 0.0 0.1 0.2 89.8 21.0 0.0 227.0 0.0 0.1 0.4 0.0 0.1 0.6 0.1 0.0 5.6 73.6 0.9 0.8 0.8 0.8 0.0 0.3 13.1 0.2 5.8 0.0 0.1 0.0 2.0 0.0 18.7 0.0 6.6 4.0 0.2 0.0 0.4 1.5 0.7 0.0 0.0 0.0 0.0 1.1 18.1 21.5 20.0 29.6 18.1 18.6 19.3 19.0 19.9 19.5 21.6 21.1 73.9 9.6 17.6 0.7 4.2 44.2 63.6 140.6 14.2 2.4 1.3 3.4 10.9 35.8 141.1 5.5 0.0 0.0 3.1 0.1 0.0 6.2 2.6 2.3 3.8 49.8 0.0 52.6 0.6 0.8 0.0 448.0 8.6 1.9 3.8 6.9 47.8 1114.8 1.1 0.0 1.0 0.0 14.2 43.8 62.1 7.4 283.9 5.7 44.4 38.4 0.3 0.3 0.0 0.0 0.2 5.3 0.0 138.8 2.6 13.0 0.0 0.5 115.6 1.4 6.6 94.2 59.6 1.4 1.0 10.9 38.2 0.1 13.2 26.3 0.0 61.5 CFHR1 "CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2" ENSG00000244414 "Complement factor H related 1" Q03591 1 196819731-196832189 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 272 "liver: 2081.3" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 320.0" "Cancer enriched" "Detected in single" 798 "liver cancer: 182.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.0;HeLa: 1.2;HL-60: 2.0;U-266/70: 2.4" "Not detected" "Not detected" "HPA038915, HPA038922, HPA040726" Supported Approved Vesicles "Secreted to blood" NA NA 13000000000 "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA038915: AB_2676269, HPA038922: AB_2676271, HPA040726: AB_2677101" "unprognostic (2.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.50e-2)" "unprognostic (1.88e-2)" "prognostic favorable (8.71e-6)" "unprognostic (3.02e-1)" "unprognostic (3.70e-1)" "unprognostic (2.50e-1)" "unprognostic (8.48e-2)" "unprognostic (7.21e-4)" "unprognostic (7.01e-4)" "unprognostic (1.13e-1)" "unprognostic (6.41e-2)" 1.5 0.6 0.1 1.8 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.2 7.6 2081.3 0.1 6.7 0.1 0.8 0.3 0.3 0.0 0.1 0.1 0.4 0.2 0.2 0.2 0.1 0.0 0.2 0.1 0.7 0.2 0.1 6.1 0.2 0.1 0.2 0.0 0.1 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.1 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.9 0.3 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.5 0.3 0.1 0.1 0.0 2.4 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.8 0.4 0.1 0.2 0.1 0.5 3.2 0.0 0.0 2.2 0.4 0.1 0.0 0.0 1.2 0.0 0.1 1.8 11.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 18.7 0.0 0.0 0.0 9.9 0.0 0.0 0.0 6.0 15.0 320.0 5.6 0.0 0.4 0.0 0.0 16.9 0.4 0.2 1.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.0 41.0 2.1 0.3 1.5 0.0 0.0 0.3 1.4 5.6 0.1 0.1 CFP PFC ENSG00000126759 "Complement factor properdin" P27918 X 47623172-47630305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 83.9;lymphoid tissue: 58.4" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 108.1;Kupffer cells: 356.7;Langerhans cells: 164.1;Macrophages: 177.3;monocytes: 473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 8 "classical monocyte: 1167.5;intermediate monocyte: 1273.6;myeloid DC: 994.5;neutrophil: 730.3;non-classical monocyte: 868.9" "Group enriched" "Detected in all" 46 "dendritic cells: 994.5;granulocytes: 730.3;monocytes: 1273.6" "Cell line enhanced" "Detected in some" "EFO-21: 20.7;HEL: 5.0;HMC-1: 5.5;NB-4: 10.7;U-937: 7.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA072644 Approved Vesicles "Secreted to blood" NA NA 6200000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 38: EFO-21 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA072644: " "unprognostic (2.77e-3)" "unprognostic (2.21e-3)" "unprognostic (1.00e-1)" "unprognostic (2.15e-2)" "unprognostic (4.15e-2)" "unprognostic (9.66e-5)" "unprognostic (9.90e-3)" "unprognostic (1.30e-2)" "unprognostic (5.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (2.70e-1)" "unprognostic (1.97e-2)" "unprognostic (2.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.62e-2)" "unprognostic (2.17e-1)" 6.0 1.9 0.3 20.5 0.3 83.9 2.1 0.3 0.6 0.6 0.2 2.1 1.2 0.9 0.2 1.6 3.4 2.1 2.6 0.4 0.1 0.8 12.0 9.3 11.7 0.1 0.0 0.7 0.8 0.1 0.8 0.9 0.0 0.7 0.9 0.2 1.0 0.2 1.0 1.5 3.7 5.2 0.0 58.4 1.5 0.6 0.0 5.1 0.9 0.7 4.4 4.9 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 20.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 5.0 0.2 0.0 0.1 1.1 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.2 0.0 10.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.2 1.0 0.0 0.1 0.5 0.1 0.4 0.4 0.1 0.1 7.2 0.0 131.5 1167.5 39.9 3.0 1273.6 2.3 6.7 15.1 1.8 994.5 2.6 21.8 8.1 730.3 12.3 868.9 30.9 14.1 1071.9 0.3 0.3 0.3 0.6 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 9.1 1.0 5.8 4.0 0.1 0.3 1.2 3.4 0.7 0.4 0.9 1.5 2.8 0.0 0.0 0.3 1.7 0.3 0.0 0.2 0.2 0.4 0.4 7.4 0.0 2.5 1.4 0.7 0.5 2.0 1.1 0.6 1.3 4.0 108.1 2.0 17.3 1.7 1.1 0.0 0.0 356.7 164.1 0.3 0.9 177.3 5.4 0.0 473.7 0.3 4.1 2.0 0.3 0.3 0.1 1.2 1.2 0.3 0.1 0.5 7.5 1.9 0.0 1.5 1.2 0.0 0.2 0.5 3.0 0.4 4.8 3.1 0.6 0.0 CHGA ENSG00000100604 "Chromogranin A" P10645 14 92923150-92935285 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 6568.4" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 6553.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 114.8" "Group enriched" "Detected in many" 16 "cerebral cortex: 326.0;white matter: 124.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 151 "SCLC-21H: 489.5;SH-SY5Y: 1339.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000023, HPA017369, CAB040544, CAB055506, CAB058688" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 295000000 100000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "CAB000023: , CAB040544: , CAB055506: AB_2081135, CAB058688: AB_2665574, HPA017369: AB_1846698" "prognostic favorable (7.85e-5)" "unprognostic (4.89e-2)" "unprognostic (5.96e-2)" "unprognostic (1.17e-1)" "unprognostic (1.43e-2)" "unprognostic (5.95e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.74e-1)" "unprognostic (2.23e-1)" "unprognostic (4.56e-2)" "prognostic favorable (4.07e-4)" "unprognostic (1.85e-1)" "unprognostic (8.81e-13)" "unprognostic (1.07e-2)" "unprognostic (1.77e-1)" "unprognostic (9.17e-2)" "prognostic unfavorable (3.99e-4)" 14.5 1248.5 8.6 9.4 11.4 0.2 0.3 0.0 326.0 8.3 0.0 92.0 242.7 0.4 0.3 1.0 1.1 0.2 0.2 4.4 1.7 1.0 0.4 1.6 0.1 14.4 0.0 0.2 102.5 6568.4 446.2 0.0 4.1 12.2 105.2 11.0 0.2 0.3 0.1 0.6 179.9 0.9 0.0 0.1 364.5 77.7 4.3 0.6 24.6 0.0 0.0 1.3 1.2 124.4 0.0 0.5 2.4 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.8 2.7 0.0 0.0 0.2 0.0 1.4 0.0 0.0 489.5 1339.4 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 4.2 0.3 0.4 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 11.4 0.0 326.0 4.4 1.7 14.4 0.0 4.1 0.0 4.3 124.4 0.1 0.0 0.0 11.1 1.0 0.9 0.4 0.0 0.0 17.3 0.2 0.3 2.9 0.0 0.0 0.0 29.2 0.3 0.0 9.8 0.0 0.1 1.3 6.0 2.3 0.8 6553.1 0.0 59.5 0.4 0.1 4.1 195.7 0.5 0.0 0.5 0.0 0.0 1.5 16.8 37.7 820.4 14.2 0.0 0.0 7.9 39.7 0.1 7.2 15.9 2.0 3.7 0.0 10.6 12.8 46.5 137.8 137.3 0.0 6.6 36.7 0.0 0.0 16.2 0.0 0.0 0.2 4.7 2.2 0.0 0.0 0.3 0.2 0.4 25.9 5.1 CHGB "SCG1, SgI" ENSG00000089199 "Chromogranin B" P05060 20 5911510-5925353 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "adrenal gland: 3466.0;pituitary gland: 1425.3" "Cell type enriched" "Detected in many" 5 "Enteroendocrine cells: 1036.1" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 154.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "SCLC-21H: 355.0;SH-SY5Y: 541.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008759, CAB009403, HPA012602" Enhanced Supported Enhanced Vesicles "Intracellular and membrane" NA NA 6500000 "Cluster 20: T-cells - T-cell receptor" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "CAB009403: AB_2081255, HPA008759: AB_1846704, HPA012602: AB_1846706" "unprognostic (1.79e-3)" "unprognostic (7.72e-2)" "unprognostic (3.48e-1)" "unprognostic (2.90e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (7.96e-3)" "unprognostic (2.86e-1)" "unprognostic (6.18e-3)" "unprognostic (7.93e-2)" "prognostic favorable (9.96e-4)" "unprognostic (8.56e-2)" "unprognostic (8.21e-2)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "unprognostic (2.73e-1)" "unprognostic (1.01e-2)" 27.5 3466.0 17.1 5.3 9.9 0.8 2.1 134.2 90.9 0.6 0.0 7.9 60.2 1.6 4.2 0.6 13.7 0.4 71.9 101.9 92.2 8.3 0.7 2.4 3.1 76.5 100.2 25.8 92.8 6.4 1425.3 0.7 188.4 5.3 14.2 56.9 6.1 3.8 11.0 1.7 31.6 0.9 12.8 0.3 133.3 14.9 19.3 4.0 9.7 0.8 1.4 0.4 2.3 14.2 0.0 7.9 0.9 0.0 0.2 0.2 0.4 0.2 0.0 0.1 0.0 1.9 0.0 0.0 4.3 0.0 4.9 0.1 0.0 0.1 0.1 0.6 0.1 2.6 0.0 1.6 0.1 4.2 0.2 1.5 0.0 0.0 2.1 0.1 0.1 0.2 0.4 0.1 1.0 0.0 0.1 0.9 19.7 1.3 0.0 0.1 0.0 0.4 0.5 0.2 355.0 541.8 0.0 0.5 0.4 2.1 0.3 0.4 0.3 0.1 6.4 0.4 3.3 0.0 0.7 2.7 0.5 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 17.1 9.9 134.2 90.9 101.9 92.2 76.5 100.2 188.4 12.8 19.3 14.2 0.0 3.2 2.4 7.5 0.3 4.2 9.9 0.8 0.0 93.3 0.1 0.3 114.4 0.0 0.7 69.9 20.9 0.1 0.0 1.6 1.9 0.5 7.1 0.2 0.7 3.0 1036.1 0.0 31.6 0.4 0.0 18.9 4.1 0.3 0.0 202.8 0.0 0.3 0.1 75.7 28.8 61.9 65.1 0.3 9.5 8.3 0.9 1.6 7.2 9.4 1.1 13.7 1.0 7.5 5.2 22.9 17.7 0.4 0.0 3.3 3.2 0.3 4.4 75.6 13.1 3.0 1.6 76.6 41.8 0.0 3.7 0.3 1.0 3.0 2.2 4.2 CHP1 "CHP, p22, p24, Sid470p, SLC9A1BP" ENSG00000187446 "Calcineurin like EF-hand protein 1" Q99653 15 41230839-41281887 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Protein kinase inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 434.4;Distal tubular cells: 389.4;Hepatocytes: 353.6;Proximal enterocytes: 425.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006616 Approved Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA006616: AB_1857461" "unprognostic (2.06e-2)" "unprognostic (3.26e-1)" "unprognostic (2.84e-1)" "prognostic favorable (9.63e-4)" "unprognostic (7.29e-2)" "unprognostic (3.74e-1)" "prognostic favorable (4.07e-6)" "unprognostic (2.20e-1)" "unprognostic (7.46e-2)" "unprognostic (3.26e-2)" "unprognostic (1.26e-3)" "unprognostic (2.79e-1)" "prognostic favorable (2.79e-6)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (4.62e-3)" "unprognostic (2.04e-1)" 66.9 55.3 22.1 28.0 24.4 58.4 32.8 26.0 26.5 34.0 24.7 113.8 85.4 21.8 34.1 74.5 20.8 48.1 53.2 30.3 32.9 76.1 185.1 52.7 18.6 32.9 31.0 19.1 42.2 54.1 21.6 26.3 35.8 34.3 81.9 20.5 49.9 27.5 81.0 45.5 70.0 27.6 26.9 20.2 112.7 10.7 33.3 20.1 49.8 86.5 41.1 44.8 41.3 28.4 72.4 72.7 28.3 109.0 120.4 113.8 41.0 56.2 69.1 44.8 48.0 66.6 140.4 12.6 59.8 77.7 47.7 89.0 56.0 83.9 51.5 44.8 20.0 50.8 58.1 103.6 93.5 66.5 73.7 116.7 98.8 51.9 53.3 68.0 82.1 37.9 81.2 79.5 52.5 43.5 27.7 72.5 29.0 118.4 35.9 35.9 46.2 34.0 92.5 144.1 17.4 44.3 96.4 178.2 48.7 49.9 101.0 66.3 108.3 47.5 50.3 76.9 36.7 45.0 131.6 59.4 84.9 42.2 44.1 255.5 227.6 274.8 49.5 204.4 51.5 40.2 46.2 50.0 152.1 33.0 29.1 41.4 173.3 56.5 207.4 95.1 60.7 116.5 22.1 24.4 26.0 26.5 30.3 32.9 32.9 31.0 35.8 26.9 33.3 28.4 28.3 44.8 117.3 20.9 26.8 72.3 62.4 48.1 20.5 11.0 101.6 39.2 80.5 243.1 50.7 103.0 10.4 33.3 38.3 434.4 389.4 96.7 52.5 68.0 48.8 39.5 55.6 58.5 24.8 150.6 62.4 38.2 112.7 114.4 37.4 18.9 78.1 353.6 68.5 11.8 21.0 136.2 34.6 170.1 134.8 122.6 29.5 77.1 129.9 19.7 113.4 32.7 36.0 9.5 23.6 173.9 206.4 29.3 24.0 80.1 425.0 231.1 33.7 10.3 26.3 46.6 41.4 13.7 19.3 50.6 108.5 66.9 32.9 65.7 161.4 130.8 CHPT1 CPT1 ENSG00000111666 "Choline phosphotransferase 1" Q8WUD6 12 101696947-101744140 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 344.4;Late spermatids: 650.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 36.9;eosinophil: 14.6" "Lineage enriched" "Detected in all" 8 "granulocytes: 36.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067643 Approved Supported Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA067643: " "unprognostic (1.59e-3)" "unprognostic (1.02e-1)" "unprognostic (1.91e-1)" "unprognostic (9.48e-2)" "unprognostic (3.15e-1)" "unprognostic (9.17e-2)" "unprognostic (5.79e-2)" "unprognostic (4.83e-2)" "unprognostic (1.12e-1)" "unprognostic (4.70e-1)" "unprognostic (5.27e-2)" "unprognostic (1.16e-2)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.72e-1)" "prognostic favorable (7.41e-4)" "unprognostic (1.79e-1)" 39.8 47.7 48.6 17.7 49.1 62.0 102.9 43.8 65.6 50.5 41.9 49.4 88.1 19.2 56.1 24.9 33.4 40.2 91.3 46.1 47.3 73.5 157.4 38.4 20.0 50.0 51.2 18.7 25.0 92.4 12.4 22.8 44.9 35.0 48.9 4.8 130.0 50.0 27.8 28.0 75.7 18.8 50.0 23.5 56.0 28.1 54.4 9.0 38.0 28.3 21.2 32.4 26.2 48.9 11.3 51.2 13.7 29.3 106.6 35.7 38.9 40.2 46.2 39.7 25.5 19.3 7.7 17.3 22.1 55.1 54.3 16.9 83.8 14.2 37.3 26.2 70.1 69.7 25.7 112.6 59.4 34.8 13.5 33.6 4.1 18.0 32.7 59.0 20.0 36.4 102.8 43.1 39.4 27.6 20.8 118.5 36.2 53.8 67.4 15.9 26.8 12.4 17.9 43.4 13.8 10.4 37.2 52.3 103.2 21.4 53.8 23.6 14.7 36.1 18.7 28.5 39.9 24.3 7.9 21.2 28.4 39.7 53.4 36.9 2.2 14.6 0.6 1.7 0.6 4.4 1.2 0.9 2.9 2.6 0.4 0.6 3.1 4.6 2.2 3.7 0.6 0.5 48.6 49.1 43.8 65.6 46.1 47.3 50.0 51.2 44.9 50.0 54.4 48.9 27.1 48.1 27.6 159.6 135.1 37.5 313.3 4.2 21.6 19.3 243.8 76.7 45.3 102.9 13.1 64.4 29.2 123.9 32.6 61.7 70.5 8.1 344.4 17.1 50.2 22.5 21.1 168.6 95.8 13.8 56.1 75.4 69.8 21.0 10.8 15.3 31.1 189.7 56.4 35.3 95.6 53.4 2.0 102.9 55.7 650.9 85.4 81.2 145.9 36.5 27.0 68.1 5.2 65.9 10.2 9.6 113.3 89.1 55.4 172.1 174.1 183.7 4.3 16.0 19.7 88.2 37.8 193.8 43.2 43.1 43.2 60.3 41.3 3.4 90.7 291.6 CHRDL2 BNF1 ENSG00000054938 "Chordin like 2" Q6WN34 11 74696429-74731426 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 145.1;gallbladder: 106.0;lymphoid tissue: 115.8;smooth muscle: 122.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 194.1;Hepatocytes: 112.2;Skeletal myocytes: 533.4" "Cancer enhanced" "Detected in many" "stomach cancer: 14.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.4;PC-3: 1.3;SiHa: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA021771, HPA076522" Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 9700000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: HeLa - Mitochondria" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "HPA021771: AB_1846689, HPA076522: " "unprognostic (2.38e-2)" "unprognostic (1.80e-1)" "unprognostic (7.24e-2)" "unprognostic (3.41e-3)" "unprognostic (9.45e-2)" "unprognostic (2.09e-1)" "unprognostic (4.08e-2)" "unprognostic (4.33e-2)" "unprognostic (6.64e-2)" "unprognostic (2.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.23e-1)" "unprognostic (7.58e-6)" "unprognostic (8.39e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (6.08e-4)" 2.7 0.2 0.6 115.8 0.4 0.0 5.1 0.4 0.7 64.7 0.1 88.7 4.1 145.1 0.8 4.1 9.4 106.0 24.4 0.4 0.6 5.2 46.3 2.9 0.4 1.0 0.6 2.5 3.1 0.4 0.4 4.5 0.7 22.6 2.6 0.5 0.5 8.9 6.6 1.2 10.8 122.1 2.3 1.3 57.7 3.4 0.7 0.0 0.9 4.8 2.8 46.3 21.2 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.4 2.4 0.3 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.4 0.7 0.4 0.6 1.0 0.6 0.7 2.3 0.7 0.2 1.2 0.0 2.6 0.7 0.3 0.3 0.5 0.2 0.0 0.0 194.1 3.8 2.2 15.7 0.1 9.2 0.0 0.0 0.8 0.0 0.0 13.8 31.4 0.6 0.2 2.1 0.0 0.0 0.1 10.3 0.1 5.3 0.0 0.5 0.0 0.2 2.9 112.2 0.1 0.0 0.2 0.0 0.0 2.4 0.0 2.4 0.0 1.1 0.0 1.0 0.0 0.0 0.0 0.5 0.1 4.1 0.0 0.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 533.4 1.2 0.6 4.3 0.0 0.0 0.1 0.5 0.4 0.0 0.5 CITED4 ENSG00000179862 "Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4" Q96RK1 1 40861054-40862363 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 172.1;Breast glandular cells: 183.7;Breast myoepithelial cells: 225.0;Cholangiocytes: 258.7;Endometrial ciliated cells: 350.4;Glandular and luminal cells: 202.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 91.3;THP-1: 264.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA056434 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Vesicles "HPA056434: AB_2683132" "unprognostic (5.39e-3)" "unprognostic (5.41e-2)" "unprognostic (1.53e-1)" "prognostic favorable (4.38e-5)" "unprognostic (3.43e-3)" "unprognostic (1.90e-2)" "unprognostic (3.44e-3)" "unprognostic (3.42e-2)" "unprognostic (2.67e-1)" "unprognostic (1.98e-3)" "unprognostic (2.25e-2)" "unprognostic (6.00e-2)" "unprognostic (2.29e-3)" "unprognostic (2.10e-1)" "unprognostic (2.11e-1)" "unprognostic (2.11e-1)" "unprognostic (6.13e-2)" 13.7 15.1 9.3 1.1 10.6 19.1 30.3 9.4 9.5 18.0 4.3 28.9 1.6 17.1 2.4 29.0 14.4 1.9 26.6 6.6 14.5 20.4 38.8 11.4 1.7 14.6 15.4 10.3 49.1 4.4 4.9 1.7 10.6 16.4 0.4 0.8 34.2 8.5 33.0 51.5 7.7 2.3 12.0 29.9 13.4 25.4 13.1 1.2 7.3 9.2 1.3 8.9 23.7 10.5 29.5 5.7 1.6 34.6 0.7 1.3 34.4 1.9 2.1 0.7 0.8 3.0 38.5 0.1 4.6 0.5 1.0 44.6 2.4 24.0 0.6 0.1 0.4 0.2 3.3 4.9 5.9 1.0 0.4 4.2 10.1 2.3 7.6 2.8 1.8 0.4 0.1 0.1 1.3 0.9 0.5 19.6 11.1 0.9 3.9 0.3 0.0 0.1 91.3 16.9 6.7 1.9 1.4 35.8 2.0 3.7 17.4 264.9 2.3 0.0 0.0 0.4 1.1 0.0 0.8 0.0 0.0 13.8 0.9 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 9.3 10.6 9.4 9.5 6.6 14.5 14.6 15.4 10.6 12.0 13.1 10.5 17.4 9.6 1.1 1.3 4.0 19.1 172.1 2.1 37.0 4.0 183.7 225.0 10.4 258.7 3.5 22.0 0.0 1.0 11.9 3.7 43.0 14.2 47.9 350.4 24.4 48.9 7.7 9.7 2.0 43.6 0.9 14.0 17.9 202.6 0.0 30.5 11.4 43.1 1.3 1.7 1.7 4.8 2.0 10.4 3.2 64.8 5.0 13.7 19.6 1.0 4.6 46.1 2.1 2.0 3.8 33.0 3.4 5.7 2.4 65.6 0.2 88.0 6.5 3.0 19.7 72.2 19.7 0.9 1.5 49.9 24.3 0.1 14.6 37.3 3.6 122.3 CKLF "C32, CKLF1, CKLF3, CKLF4, HSPC224, UCK-1" ENSG00000217555 "Chemokine like factor" Q9UBR5 16 66552563-66566251 "Predicted membrane proteins, Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 345.1;Spermatocytes: 300.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1384.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA062779 Approved Vesicles "Secreted to blood" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062779: AB_2684867" "unprognostic (1.64e-2)" "unprognostic (2.17e-2)" "unprognostic (1.88e-1)" "unprognostic (4.97e-2)" "unprognostic (3.06e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (2.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.79e-2)" "unprognostic (8.05e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.06e-9)" "unprognostic (2.36e-1)" "unprognostic (2.65e-1)" "prognostic favorable (2.22e-4)" "unprognostic (1.07e-1)" 36.5 31.1 26.3 54.8 26.2 68.2 36.0 27.4 29.8 27.7 25.9 42.1 31.8 23.8 27.4 19.2 31.1 40.3 16.5 25.7 28.8 21.0 29.6 36.2 61.5 28.1 27.6 25.6 17.9 58.0 19.7 29.7 28.9 15.5 42.5 9.7 19.7 18.4 14.8 16.9 38.7 33.5 27.9 67.0 25.6 56.8 26.4 90.0 23.7 20.1 51.2 46.1 20.0 29.6 194.6 169.2 34.7 101.5 92.7 76.1 25.5 95.2 72.4 101.7 150.9 158.8 231.4 75.8 116.6 81.8 106.4 102.5 70.5 57.2 142.1 94.2 35.3 55.5 145.0 197.3 56.0 175.7 144.1 52.0 45.3 126.9 44.9 122.1 122.8 229.4 90.8 212.8 129.2 64.8 169.9 172.1 11.5 114.0 273.1 287.5 184.2 215.6 343.2 106.3 48.8 58.8 290.5 19.3 93.0 23.3 55.5 116.5 76.6 146.5 131.8 51.0 113.5 100.3 224.0 393.0 123.5 151.5 121.1 807.1 380.9 773.3 187.6 203.9 238.9 100.6 174.8 186.6 317.6 97.7 92.7 126.4 1384.5 187.6 199.2 161.6 236.0 401.2 26.3 26.2 27.4 29.8 25.7 28.8 28.1 27.6 28.9 27.9 26.4 29.6 65.7 19.2 49.0 0.0 68.7 27.3 24.7 84.2 12.0 8.4 80.8 94.0 1.8 87.2 50.8 57.0 0.0 54.8 109.7 57.1 17.6 141.4 67.7 34.8 21.5 52.4 33.0 63.5 0.0 130.0 117.7 38.6 21.4 17.5 345.1 17.7 67.5 38.4 247.4 1.7 0.0 73.6 61.1 138.2 238.4 31.4 49.4 244.2 40.9 0.0 157.8 28.1 188.4 0.0 0.0 224.2 51.3 30.1 94.6 10.0 95.9 83.4 79.3 9.0 32.9 24.5 38.1 300.0 77.1 30.8 23.0 17.4 192.6 23.9 79.0 25.8 CLCN3 "ClC-3, CLC3" ENSG00000109572 "Chloride voltage-gated channel 3" P51790 4 169612633-169723673 "Predicted intracellular proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044723 Approved Supported Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA044723: AB_10959733" "unprognostic (1.92e-1)" "unprognostic (3.92e-2)" "unprognostic (1.95e-3)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (2.25e-1)" "unprognostic (3.32e-1)" "unprognostic (1.79e-1)" "unprognostic (5.40e-2)" "unprognostic (1.30e-1)" "prognostic favorable (1.10e-4)" "unprognostic (2.49e-2)" "unprognostic (2.49e-1)" "unprognostic (1.45e-1)" "unprognostic (6.38e-3)" 21.1 34.5 20.1 20.6 28.7 12.3 31.9 29.1 30.2 23.9 20.5 47.5 30.1 18.7 29.4 40.7 26.4 38.0 35.3 22.8 30.5 36.4 25.7 21.2 17.3 32.3 41.0 23.1 41.0 37.2 18.2 24.1 32.1 32.7 52.6 78.3 78.0 21.8 24.7 29.1 29.8 17.8 32.3 16.7 41.2 33.3 26.5 21.0 37.0 22.1 24.5 37.4 17.1 42.0 32.6 33.2 48.7 62.1 96.1 80.8 24.0 42.9 53.5 28.3 34.3 23.7 72.2 40.0 26.1 35.9 32.7 27.2 61.2 26.6 46.9 35.9 24.4 33.8 50.6 27.3 65.8 41.0 54.2 56.6 59.7 50.5 49.5 117.4 51.7 55.2 85.1 88.0 49.7 11.8 56.2 9.4 20.0 56.2 22.4 25.0 21.5 31.6 58.1 66.6 51.9 51.5 38.4 40.9 66.9 39.3 27.9 19.2 43.5 22.5 25.3 36.5 33.7 39.3 64.3 35.5 67.6 15.4 60.8 3.8 4.1 2.9 5.0 4.8 6.5 5.0 3.7 4.7 5.7 3.8 5.7 5.2 2.9 4.5 4.0 7.1 4.7 4.7 20.1 28.7 29.1 30.2 22.8 30.5 32.3 41.0 32.1 32.3 26.5 42.0 35.5 32.1 26.2 58.8 30.7 11.3 25.7 21.5 20.5 90.3 54.6 27.9 66.5 42.9 25.3 62.5 131.3 23.8 23.1 118.3 7.9 37.2 88.1 46.9 35.9 35.2 66.9 83.1 102.4 44.3 18.7 29.5 51.5 51.8 113.0 32.3 38.6 39.3 18.6 60.6 126.1 64.2 20.3 32.9 9.8 67.4 24.5 47.8 32.0 44.0 17.1 136.7 28.8 139.7 141.5 31.9 55.3 21.1 21.4 45.3 37.1 17.9 67.8 115.1 6.6 34.6 21.5 17.2 15.5 42.8 26.1 71.1 21.0 67.0 65.4 34.0 CLCN4 "ClC-4, CLC4" ENSG00000073464 "Chloride voltage-gated channel 4" P51793 X 10156975-10237660 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.3;retina: 37.9;skeletal muscle: 45.0;tongue: 34.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.0;Cone photoreceptor cells: 102.2;Excitatory neurons: 45.7;Horizontal cells: 52.2;Inhibitory neurons: 54.0;Oligodendrocytes: 76.5;Rod photoreceptor cells: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 6 "B-cells: 2.6;granulocytes: 2.2" "Cell line enhanced" "Detected in many" "GAMG: 25.3;HEL: 24.3;SCLC-21H: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031313, HPA063637" Enhanced Approved Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA031313: AB_10601358, HPA063637: AB_2685069" "unprognostic (1.01e-1)" "unprognostic (1.20e-2)" "unprognostic (5.07e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (2.96e-1)" "unprognostic (3.75e-1)" "unprognostic (1.04e-2)" "unprognostic (3.66e-1)" "unprognostic (1.75e-1)" "unprognostic (5.99e-2)" "prognostic favorable (9.55e-4)" "unprognostic (9.70e-2)" "unprognostic (9.78e-3)" "unprognostic (1.68e-1)" "unprognostic (1.49e-1)" "unprognostic (1.32e-1)" "unprognostic (1.74e-1)" 2.6 2.7 16.2 1.5 27.4 1.8 1.1 28.8 23.1 1.3 5.2 0.9 0.8 0.6 22.6 1.7 2.9 2.1 12.3 19.6 19.7 2.8 3.2 3.0 2.8 27.1 24.1 1.6 2.2 10.8 5.3 1.1 24.5 1.5 0.7 37.9 2.2 1.0 45.0 1.0 0.7 0.7 18.5 2.6 1.5 1.8 26.8 2.6 6.5 34.2 1.8 1.2 0.7 33.3 5.9 4.6 2.7 0.0 1.5 2.5 0.1 0.2 0.0 0.0 0.0 9.1 4.6 5.0 13.0 1.5 25.3 1.4 1.4 2.9 0.2 0.1 5.7 24.3 2.2 3.5 7.3 0.0 0.1 12.9 3.4 7.0 1.5 4.7 9.4 0.0 1.5 0.1 3.3 1.1 0.0 0.2 4.0 7.1 15.3 0.0 4.5 0.0 2.1 0.8 24.1 8.7 8.6 1.1 0.0 2.7 1.7 2.7 7.4 3.1 5.8 15.3 0.6 0.5 12.1 1.8 10.5 0.0 4.5 1.6 0.3 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.4 2.6 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.3 16.2 27.4 28.8 23.1 19.6 19.7 27.1 24.1 24.5 18.5 26.8 33.3 1.0 9.6 3.1 11.8 4.9 0.5 0.6 2.0 0.0 85.0 1.1 0.4 31.1 8.6 2.2 7.3 102.2 0.2 0.0 0.1 0.0 2.5 0.1 2.6 1.3 3.0 15.0 9.4 45.7 3.6 0.1 4.0 1.1 3.1 1.3 0.7 13.6 5.1 3.1 52.2 54.0 0.6 4.1 4.8 2.3 0.0 0.9 3.4 0.0 15.9 1.0 15.4 0.0 24.6 76.5 4.1 0.1 3.8 0.4 0.8 0.0 2.9 5.3 42.6 0.0 8.7 6.0 0.0 0.5 0.2 0.1 0.3 0.1 2.6 0.3 1.3 CLDN14 DFNB29 ENSG00000159261 "Claudin 14" O95500 21 36460621-36576569 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "kidney: 13.8;liver: 39.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 7.2;Distal tubular cells: 19.6;Ductal cells: 11.8;Exocrine glandular cells: 8.2;Hepatocytes: 22.2;Pancreatic endocrine cells: 21.3" "Cancer enriched" "Detected in many" 6 "liver cancer: 7.9" "Region enriched" "Detected in single" 5 "cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "HDLM-2: 224.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA054707 Uncertain Vesicles NA NA "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA054707: " "unprognostic (1.14e-1)" "unprognostic (2.21e-1)" "unprognostic (3.74e-2)" "unprognostic (9.43e-2)" "unprognostic (8.20e-3)" "unprognostic (5.54e-2)" "prognostic favorable (1.53e-4)" "unprognostic (3.50e-4)" "unprognostic (2.28e-1)" "unprognostic (2.30e-2)" "unprognostic (2.12e-2)" "unprognostic (4.87e-1)" "unprognostic (7.44e-4)" "unprognostic (2.77e-2)" "unprognostic (7.65e-2)" "unprognostic (2.45e-2)" "unprognostic (9.71e-2)" 0.1 0.0 0.2 0.3 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.3 0.1 0.1 0.0 13.8 39.5 0.1 0.0 0.1 0.0 0.0 1.0 0.1 0.0 0.2 0.1 0.0 0.1 0.3 0.2 0.0 0.4 0.4 0.1 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.4 0.0 0.0 0.0 0.0 224.1 0.0 0.0 0.0 0.1 0.0 0.0 3.3 0.0 0.0 0.1 0.0 0.7 2.1 0.1 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 2.5 15.8 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.1 7.4 4.2 0.1 0.7 0.4 6.7 15.7 0.0 1.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.4 1.0 0.6 0.0 0.0 0.8 0.4 0.7 7.2 0.1 1.8 0.0 0.1 0.0 0.7 19.6 11.8 0.6 0.3 0.2 3.6 0.0 0.0 0.6 8.2 1.3 0.1 0.0 3.4 0.0 0.0 0.4 22.2 0.1 0.0 0.4 0.6 0.0 0.6 0.0 0.5 0.0 0.2 3.6 0.0 0.6 0.0 0.0 1.5 1.0 21.3 0.0 0.4 6.9 0.6 0.0 0.7 0.0 0.0 0.0 0.0 2.0 1.2 0.0 0.0 0.3 0.8 1.4 0.0 0.3 2.3 CLIP4 "FLJ21069, RSNL2" ENSG00000115295 "CAP-Gly domain containing linker protein family member 4" Q8N3C7 2 29097705-29189643 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 169.2;Inhibitory neurons: 142.8;Oligodendrocyte precursor cells: 130.2;Oligodendrocytes: 247.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 25.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 83.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043366, HPA056246" Uncertain Enhanced Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA043366: AB_10963051, HPA056246: AB_2683078" "unprognostic (1.97e-2)" "unprognostic (1.49e-2)" "unprognostic (2.14e-2)" "unprognostic (2.47e-3)" "unprognostic (3.64e-1)" "unprognostic (6.82e-2)" "unprognostic (1.15e-2)" "unprognostic (8.82e-3)" "unprognostic (3.62e-1)" "unprognostic (4.32e-2)" "unprognostic (2.73e-1)" "unprognostic (7.99e-2)" "prognostic unfavorable (1.83e-4)" "unprognostic (3.59e-3)" "unprognostic (6.35e-2)" "unprognostic (2.14e-1)" "unprognostic (1.99e-2)" 19.3 9.8 15.1 9.5 24.7 1.9 14.2 20.6 19.7 14.3 18.3 20.8 4.8 13.7 8.7 23.4 15.5 13.4 30.0 15.2 18.9 9.0 4.5 18.7 10.2 20.6 21.8 22.7 6.3 14.3 20.0 16.4 20.9 16.6 7.0 17.9 13.9 15.2 71.9 30.9 10.7 18.6 18.6 10.0 10.2 17.5 18.1 13.5 33.5 43.8 10.7 20.8 19.9 31.4 82.3 22.6 3.4 12.1 31.4 47.0 0.1 31.8 54.4 17.5 19.9 0.7 52.7 10.2 15.9 55.1 69.9 33.0 3.6 24.7 24.8 18.9 5.4 0.0 29.1 1.2 79.7 0.0 16.2 33.3 61.3 23.2 83.8 62.8 12.4 7.4 0.5 31.5 26.7 0.6 7.9 3.6 0.9 4.8 5.0 0.1 20.1 1.6 32.0 14.4 5.3 13.7 27.6 11.2 29.0 3.3 0.0 4.9 39.4 4.1 31.6 13.7 13.8 16.2 0.1 0.1 19.0 0.0 12.7 2.5 6.1 0.2 7.9 14.8 12.4 1.4 6.1 8.4 2.4 0.5 6.9 6.8 1.2 5.6 25.9 0.0 2.3 5.6 15.1 24.7 20.6 19.7 15.2 18.9 20.6 21.8 20.9 18.6 18.1 31.4 0.9 64.1 15.0 78.7 7.2 17.1 27.6 26.8 30.1 31.0 11.4 8.9 76.2 0.0 18.5 12.9 29.2 6.7 18.6 0.1 3.9 10.7 169.2 16.1 8.4 2.5 0.0 2.5 75.1 9.1 1.7 26.5 4.1 12.9 5.1 13.1 1.4 1.8 9.9 20.2 142.8 0.0 8.2 36.1 6.0 91.1 27.4 25.9 8.8 15.9 17.5 18.7 19.6 130.2 247.2 22.1 0.0 24.0 30.9 25.8 0.0 5.9 32.1 17.9 13.1 24.2 9.2 9.4 1.6 29.7 27.3 21.5 21.9 16.4 0.2 24.2 CLNK MIST ENSG00000109684 "Cytokine dependent hematopoietic cell linker" Q7Z7G1 4 10486395-10684768 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 6.2" "Cell type enriched" "Detected in many" 5 "Ionocytes: 73.2" "Cancer enriched" "Detected in single" 13 "renal cancer: 3.3" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "HDLM-2: 4.1;U-937: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035671, HPA035672" Uncertain Uncertain Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA035671: AB_10669673, HPA035672: AB_10669775" "unprognostic (2.47e-3)" "unprognostic (4.74e-4)" "unprognostic (1.99e-4)" "unprognostic (2.24e-3)" "unprognostic (1.17e-1)" "unprognostic (2.23e-6)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" "unprognostic (9.87e-2)" "unprognostic (3.75e-2)" "unprognostic (2.55e-1)" "unprognostic (7.74e-3)" "unprognostic (1.55e-1)" "unprognostic (6.05e-3)" "unprognostic (6.65e-3)" "unprognostic (1.45e-1)" "unprognostic (2.99e-2)" 0.3 0.2 0.5 0.9 0.4 0.4 0.6 1.5 0.7 0.2 0.5 0.3 0.6 0.4 1.2 0.4 0.2 0.5 0.2 0.5 0.5 6.2 0.9 0.6 3.0 0.4 0.2 0.4 0.1 0.1 1.3 1.0 0.5 0.4 0.4 0.3 0.5 0.3 0.2 0.8 0.9 0.1 0.1 1.5 1.1 0.8 0.5 1.4 0.3 0.0 2.0 0.3 0.0 0.9 0.0 0.2 0.2 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 4.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.2 0.3 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.4 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.2 2.2 0.1 0.5 0.1 0.2 0.2 0.1 0.1 1.4 0.4 0.1 2.6 1.1 0.1 0.1 0.4 2.0 0.0 0.6 1.8 0.2 0.5 0.4 1.5 0.7 0.5 0.5 0.4 0.2 0.5 0.1 0.5 0.9 0.1 3.2 3.0 1.0 12.9 0.8 0.8 0.0 0.0 1.3 0.3 0.3 0.7 0.0 0.9 0.0 2.1 0.3 4.6 0.1 13.7 0.0 5.3 0.7 0.2 0.4 0.0 5.3 1.7 0.0 2.2 0.5 0.5 0.9 11.4 0.2 0.7 0.3 0.3 0.0 1.6 0.2 73.2 1.9 5.5 5.4 0.3 3.5 1.8 1.9 0.5 0.4 0.0 1.0 0.7 0.1 0.0 2.2 1.1 0.7 0.0 0.2 0.2 1.0 0.0 1.1 0.5 1.9 0.8 0.0 0.4 0.1 6.0 1.3 0.0 0.7 CLTCL1 "CHC22, CLH22, CLTCL, CLTD" ENSG00000070371 "Clathrin heavy chain like 1" P53675 22 19179473-19291719 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 187.4;testis: 47.2;tongue: 61.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 11.3;Cone photoreceptor cells: 14.6;Early spermatids: 19.3;Late spermatids: 17.0;Oligodendrocyte precursor cells: 12.5;Oligodendrocytes: 12.5;Spermatocytes: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 2.1;neutrophil: 5.2" "Group enriched" "Detected in many" 20 "granulocytes: 5.2;monocytes: 2.1" "Cell line enhanced" "Detected in many" "HMC-1: 64.8;K-562: 31.8" "HPA075327, HPA075795" Enhanced Approved Vesicles NA NA 2300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA075327: , HPA075795: AB_2686764" "unprognostic (1.29e-2)" "unprognostic (3.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.16e-3)" "unprognostic (8.20e-2)" "unprognostic (6.93e-3)" "unprognostic (1.60e-1)" "unprognostic (3.28e-1)" "unprognostic (4.42e-2)" "unprognostic (2.93e-3)" "unprognostic (3.14e-1)" "unprognostic (1.02e-1)" "unprognostic (1.20e-1)" "unprognostic (8.71e-4)" "unprognostic (1.61e-1)" "unprognostic (2.10e-2)" "unprognostic (1.06e-1)" 6.8 16.0 5.4 0.8 6.1 15.6 4.8 6.2 6.5 5.0 5.0 2.4 0.5 3.1 1.6 3.6 3.8 1.2 14.8 5.2 7.8 3.2 6.5 3.0 0.7 7.4 8.6 3.6 2.5 2.1 13.4 1.5 8.5 5.2 1.0 2.0 3.9 0.8 187.4 4.1 1.8 1.7 5.7 3.5 2.8 47.2 9.1 3.9 8.0 61.3 0.5 2.8 3.7 6.9 4.5 4.6 3.0 4.9 10.8 5.9 1.4 3.1 3.3 4.2 6.3 1.7 1.4 1.9 0.4 7.0 3.3 1.5 4.7 8.5 3.5 0.3 4.6 0.2 4.4 5.3 5.5 6.5 64.8 25.0 7.0 7.8 10.9 12.5 2.7 2.4 31.8 1.7 10.0 3.6 0.6 22.4 3.8 18.1 2.8 2.4 24.2 0.1 3.4 1.8 6.9 1.2 6.6 4.1 0.4 3.6 8.9 27.1 0.8 7.6 15.5 4.2 5.2 3.1 8.4 0.8 4.5 17.4 1.6 0.0 2.1 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.4 5.4 6.1 6.2 6.5 5.2 7.8 7.4 8.6 8.5 5.7 9.1 6.9 1.4 3.2 0.5 9.4 0.1 0.6 0.5 1.0 1.2 2.4 0.7 0.3 11.3 1.5 1.8 0.0 14.6 0.4 0.2 1.2 0.0 0.8 19.3 1.2 1.9 0.9 0.0 0.8 4.5 0.0 0.2 1.4 1.5 1.4 0.0 3.5 1.1 2.4 0.3 0.0 8.9 1.3 6.1 1.0 0.7 17.0 2.5 0.5 0.0 4.7 1.3 1.5 0.0 12.5 12.5 1.2 0.8 4.1 0.1 1.3 0.2 1.3 1.0 2.0 0.0 2.6 4.5 14.5 4.7 1.0 0.9 1.1 0.1 6.2 0.9 0.0 CMTM6 "CKLFSF6, FLJ20396" ENSG00000091317 "CKLF like MARVEL transmembrane domain containing 6" Q9NX76 3 32481312-32502852 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 815.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026980, HPA063491" Enhanced Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" Vesicles "HPA026980: AB_10602801, HPA063491: " "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.34e-2)" "unprognostic (1.81e-2)" "unprognostic (7.25e-2)" "unprognostic (8.20e-2)" "unprognostic (2.95e-2)" "unprognostic (1.99e-1)" "unprognostic (2.44e-3)" "unprognostic (2.95e-1)" "unprognostic (1.04e-3)" "unprognostic (6.79e-2)" "unprognostic (2.27e-1)" "unprognostic (7.23e-2)" "unprognostic (6.58e-2)" "unprognostic (3.74e-2)" "unprognostic (1.55e-3)" 40.3 26.2 11.6 69.0 11.4 97.3 54.4 11.7 13.5 50.4 24.8 47.7 26.7 46.3 41.0 40.3 176.6 50.3 18.5 10.8 13.4 40.0 132.4 54.3 53.9 14.5 12.5 18.6 23.5 41.6 9.2 70.1 14.3 48.6 58.4 13.0 33.2 39.9 5.0 49.4 29.5 41.6 14.5 55.4 46.9 40.4 13.5 47.8 61.7 13.6 78.3 79.0 18.9 14.7 107.4 34.2 66.5 50.1 112.1 111.0 292.4 77.5 110.4 79.7 91.5 36.6 174.4 63.5 86.1 104.6 53.8 67.6 47.0 128.9 108.2 285.4 57.3 80.4 22.8 54.5 79.6 135.3 153.0 110.5 81.3 92.0 68.6 128.2 130.3 60.9 39.8 116.0 103.0 33.4 81.9 70.0 59.3 88.6 50.0 68.6 51.7 49.9 111.1 147.9 15.3 44.3 70.5 39.5 76.1 66.9 58.3 133.5 117.8 88.0 57.9 86.7 94.1 59.6 63.9 58.6 61.4 116.8 112.1 176.8 84.4 208.0 29.1 133.4 32.8 54.4 38.1 28.3 72.7 42.2 22.0 24.7 313.4 65.1 210.2 38.6 46.3 108.6 11.6 11.4 11.7 13.5 10.8 13.4 14.5 12.5 14.3 14.5 13.5 14.7 57.0 35.3 49.9 12.4 243.7 96.0 82.4 159.3 55.2 13.9 233.0 57.5 5.8 60.1 112.0 95.6 12.5 253.6 122.5 88.0 33.2 113.8 12.3 129.1 68.3 70.7 132.1 41.2 14.2 83.0 101.7 74.9 63.2 180.9 126.8 186.5 124.9 305.2 156.5 50.5 19.2 117.6 118.0 310.1 815.8 8.4 39.4 326.0 81.8 30.0 425.8 130.1 71.1 18.1 9.4 136.7 46.1 42.9 104.7 147.1 23.8 63.4 183.0 17.3 39.5 32.9 74.3 36.1 20.2 89.7 126.6 261.7 120.9 50.3 64.6 110.3 CNIH1 "CNIH, CNIL, TGAM77" ENSG00000100528 "Cornichon family AMPA receptor auxiliary protein 1" O95406 14 54423561-54441391 "Predicted membrane proteins, Transporters" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002544 Approved Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA002544: AB_2081856" "unprognostic (1.06e-1)" "unprognostic (1.18e-3)" "unprognostic (7.09e-2)" "unprognostic (5.06e-2)" "unprognostic (1.50e-1)" "unprognostic (8.93e-3)" "unprognostic (1.47e-1)" "unprognostic (2.71e-3)" "unprognostic (4.78e-2)" "unprognostic (4.62e-1)" "unprognostic (1.38e-2)" "unprognostic (1.79e-1)" "unprognostic (4.12e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-1)" "unprognostic (1.71e-2)" "prognostic unfavorable (8.95e-4)" 73.2 61.7 40.2 50.9 42.1 37.2 73.6 45.2 49.5 59.8 58.5 86.9 99.4 49.6 50.8 72.5 67.0 74.4 84.6 42.8 47.2 79.9 232.9 46.7 61.2 44.3 43.4 44.0 41.8 59.8 41.2 58.4 44.8 57.2 95.1 60.3 49.7 57.1 58.9 36.0 85.4 68.2 49.1 33.8 45.4 37.1 41.3 56.2 65.0 95.5 79.0 95.1 39.4 50.7 233.4 141.3 113.8 129.2 301.0 380.9 107.8 276.8 348.6 232.0 264.4 86.5 316.4 289.7 180.2 209.2 141.6 226.5 208.3 200.3 287.5 111.9 124.5 112.1 80.9 152.8 303.6 136.5 90.2 314.4 244.3 217.1 304.0 236.8 221.3 117.7 111.5 95.5 262.4 138.4 151.5 102.9 84.2 266.3 281.3 114.8 191.8 97.3 264.2 171.4 95.5 106.3 163.4 127.8 316.7 104.8 197.5 144.9 143.7 194.7 192.9 165.4 167.8 59.7 138.8 141.2 235.9 115.3 176.5 5.3 84.6 10.7 32.5 66.8 54.8 64.3 57.3 47.0 86.0 55.2 75.1 52.1 20.9 44.0 53.7 48.4 65.1 96.6 40.2 42.1 45.2 49.5 42.8 47.2 44.3 43.4 44.8 49.1 41.3 50.7 41.1 35.3 60.6 14.7 64.9 105.7 86.2 186.1 141.7 41.9 69.2 64.0 85.6 50.1 79.8 46.0 20.9 95.7 48.1 98.8 90.1 89.3 44.4 54.8 57.9 72.3 104.4 65.0 26.9 62.3 123.4 90.3 52.5 32.8 197.3 32.4 70.3 140.0 115.5 67.3 34.8 91.5 99.7 102.8 80.0 17.0 60.0 73.5 83.6 9.4 110.3 59.9 35.0 17.6 22.5 65.6 96.6 65.8 84.0 92.0 149.9 164.7 79.9 45.1 46.0 60.5 68.1 68.7 64.1 144.9 110.0 70.9 69.3 68.4 123.0 91.4 CNNM2 ACDP2 ENSG00000148842 "Cyclin and CBS domain divalent metal cation transport mediator 2" Q9H8M5 10 102918294-103090222 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, Epilepsy, Mental retardation, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 37.9;parathyroid gland: 31.6" "Cell type enhanced" "Detected in many" "Astrocytes: 60.1;Excitatory neurons: 112.6;Inhibitory neurons: 146.9;Oligodendrocyte precursor cells: 92.5;Oligodendrocytes: 92.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.5" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059954, HPA071631" Enhanced Vesicles NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 16: U-266 - Nucleosome" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA059954: AB_2684177, HPA071631: AB_2686427" "unprognostic (2.18e-1)" "unprognostic (6.46e-2)" "unprognostic (1.24e-1)" "unprognostic (2.65e-3)" "unprognostic (3.19e-1)" "unprognostic (2.44e-1)" "unprognostic (1.93e-1)" "unprognostic (4.80e-2)" "unprognostic (4.51e-3)" "unprognostic (3.75e-2)" "unprognostic (1.29e-2)" "unprognostic (2.39e-1)" "prognostic favorable (2.39e-8)" "unprognostic (2.44e-1)" "unprognostic (1.13e-1)" "unprognostic (2.65e-3)" "unprognostic (1.56e-1)" 3.3 11.5 5.1 2.3 5.5 9.3 2.5 7.9 5.7 3.7 37.9 7.0 3.8 3.6 2.1 1.7 4.8 4.1 2.1 4.2 3.3 9.1 4.8 3.8 1.5 4.9 4.8 4.8 3.6 31.6 5.7 8.7 4.7 2.7 6.4 5.0 3.0 3.0 1.6 4.5 4.5 3.7 1.8 2.1 3.3 4.5 4.6 1.8 5.6 1.5 1.1 3.2 2.9 9.7 5.0 8.1 3.1 8.5 7.8 3.2 8.6 2.3 9.7 3.1 3.9 5.8 4.3 1.9 3.5 3.4 6.0 6.3 6.9 4.6 2.4 3.3 12.1 2.8 4.2 11.8 4.6 2.0 3.6 4.2 6.6 3.2 10.7 7.9 1.9 5.5 4.8 10.9 1.8 8.6 2.3 2.2 5.1 4.9 5.0 5.5 4.0 2.4 2.4 2.9 4.5 5.8 5.9 1.3 6.3 9.1 10.4 3.7 1.6 4.2 6.2 3.0 4.2 11.7 14.1 3.6 7.4 6.6 1.7 0.3 0.1 0.1 0.2 0.2 0.2 0.3 0.1 0.1 0.1 0.1 0.2 0.1 0.2 1.5 0.0 0.3 0.3 0.1 5.1 5.5 7.9 5.7 4.2 3.3 4.9 4.8 4.7 1.8 4.6 9.7 3.0 6.4 8.4 60.1 7.9 2.4 2.3 1.7 6.8 16.4 3.3 2.4 4.5 2.8 5.6 5.5 12.5 18.8 8.1 46.7 1.9 2.2 10.7 7.4 4.2 4.2 6.7 6.7 112.6 5.4 3.4 6.3 12.8 6.4 3.8 13.7 3.3 6.1 3.8 32.0 146.9 5.0 0.0 3.2 2.5 15.1 3.4 4.7 7.2 39.4 2.3 7.0 2.1 92.5 92.3 2.3 9.0 3.4 6.2 2.0 11.7 5.5 9.5 15.8 13.1 5.7 16.7 15.5 6.9 8.1 4.1 39.8 5.1 3.8 11.6 2.2 CNPY4 "MGC40499, PRAT4B" ENSG00000166997 "Canopy FGF signaling regulator 4" Q8N129 7 100119634-100125508 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.3;Leydig cells: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014166, HPA025240" Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA014166: AB_1853895, HPA025240: AB_2082630" "unprognostic (9.64e-2)" "unprognostic (1.59e-2)" "unprognostic (4.09e-3)" "unprognostic (8.44e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.71e-1)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.86e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (6.16e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.59e-5)" "unprognostic (6.92e-2)" "unprognostic (1.80e-1)" "unprognostic (1.88e-1)" "unprognostic (1.35e-2)" 13.7 16.8 13.3 9.6 13.9 6.1 11.0 14.3 14.9 24.6 14.7 14.1 6.4 21.2 14.8 5.7 15.4 16.7 13.1 13.1 13.7 10.4 6.6 9.2 10.8 14.2 13.8 24.5 4.5 12.8 16.6 21.3 14.1 10.8 9.9 17.2 5.7 15.9 5.1 8.3 9.7 21.4 13.8 13.6 7.8 6.8 13.6 14.3 10.4 7.1 9.8 12.4 14.8 14.3 7.9 13.5 33.2 59.6 76.0 36.5 16.6 29.0 31.2 14.9 27.8 7.5 7.0 17.2 32.9 52.5 10.9 7.9 13.0 14.2 15.6 16.2 13.4 7.1 23.3 10.4 21.5 12.1 12.8 33.4 3.8 13.7 6.2 32.7 52.4 8.2 6.0 11.1 21.5 22.9 25.8 15.9 17.1 5.0 19.2 7.5 24.9 9.2 15.4 2.0 8.3 16.9 27.8 22.4 15.4 21.4 11.3 6.7 42.9 47.5 28.5 20.2 13.3 9.4 16.3 15.3 27.8 18.4 19.7 11.8 5.1 8.6 15.1 11.2 19.8 3.9 15.6 19.0 7.2 2.9 12.7 19.0 2.3 12.3 13.9 4.6 13.8 6.7 13.3 13.9 14.3 14.9 13.1 13.7 14.2 13.8 14.1 13.8 13.6 14.3 15.2 6.4 2.6 4.2 3.4 3.6 2.3 7.9 2.8 6.9 3.4 6.2 3.4 5.7 4.0 12.9 2.1 35.3 5.2 3.7 1.9 6.4 0.5 5.1 20.2 15.0 2.4 11.8 3.4 2.5 10.3 28.4 1.1 4.2 9.5 16.1 18.2 1.3 14.0 8.4 4.0 1.9 4.1 2.5 2.4 2.2 35.1 4.7 16.0 2.8 5.1 26.6 8.2 2.0 2.8 2.4 2.8 31.6 1.9 0.5 2.8 3.3 4.4 15.8 13.1 12.7 15.5 1.1 4.5 2.1 3.8 18.3 8.6 30.5 2.3 1.0 CNST "C1orf71, FLJ32001, PPP1R64" ENSG00000162852 "Consortin, connexin sorting protein" Q6PJW8 1 246566444-246668595 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007225, HPA007226" Approved Supported Vesicles NA NA 480000 "Cluster 37: B-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Vesicles "HPA007225: AB_1848869, HPA007226: AB_2667782" "unprognostic (1.55e-2)" "unprognostic (9.75e-2)" "unprognostic (3.33e-2)" "unprognostic (9.76e-2)" "unprognostic (2.78e-1)" "unprognostic (4.28e-2)" "unprognostic (3.72e-2)" "unprognostic (7.28e-3)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (3.52e-2)" "unprognostic (3.47e-2)" "unprognostic (2.73e-3)" "unprognostic (6.17e-2)" "unprognostic (2.63e-1)" "unprognostic (8.77e-3)" "unprognostic (2.26e-1)" 13.1 19.2 8.8 10.5 9.7 23.5 10.9 14.4 16.1 9.0 17.1 13.7 10.2 9.0 8.1 16.7 8.8 8.7 8.9 10.3 11.1 8.6 23.5 9.9 16.7 6.9 7.8 10.5 10.2 11.3 7.5 9.3 8.4 8.1 12.0 16.8 7.2 7.3 31.8 10.1 13.2 10.1 5.6 10.4 8.4 12.9 7.6 14.3 13.9 39.0 13.4 11.3 8.8 9.5 8.4 11.0 7.9 7.0 12.8 14.7 16.0 26.9 26.5 26.7 20.2 10.5 10.9 24.6 11.7 26.9 7.9 8.6 12.3 9.2 36.2 13.8 4.2 28.9 10.4 8.0 18.4 14.5 53.5 14.0 8.7 25.9 27.4 13.2 8.4 13.0 37.3 10.5 15.3 6.1 15.9 6.7 25.9 11.7 9.5 15.5 14.2 20.1 10.1 24.4 18.0 21.6 11.5 6.7 34.0 9.2 12.3 12.6 12.0 33.0 7.9 13.8 18.5 31.8 43.8 25.0 8.1 21.2 32.5 47.1 8.1 23.9 14.4 8.8 16.1 35.6 24.8 13.6 8.1 35.7 31.1 16.9 10.7 15.1 22.2 11.7 33.2 15.9 8.8 9.7 14.4 16.1 10.3 11.1 6.9 7.8 8.4 5.6 7.6 9.5 41.3 12.8 17.2 21.2 46.0 24.9 21.5 6.7 27.3 31.5 10.2 7.5 14.3 12.8 17.7 3.7 14.6 4.0 18.2 46.9 7.9 6.9 44.7 43.7 17.2 29.0 15.0 25.2 58.5 6.0 6.2 22.5 16.3 68.3 40.4 8.1 30.0 22.1 10.0 16.8 54.1 19.3 10.2 12.5 12.2 41.6 9.6 32.9 14.2 22.5 10.1 14.9 18.6 43.2 35.7 8.8 31.4 7.9 26.4 16.4 42.7 5.9 23.4 24.4 13.1 20.6 29.2 16.7 13.1 20.6 26.9 9.3 31.7 8.3 14.3 23.3 CNTF HCNTF ENSG00000242689 "Ciliary neurotrophic factor" P26441 11 58622665-58625733 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.9;brain: 7.7" "Cell type enhanced" "Detected in single" "Melanocytes: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 7.9" "Low region specificity" "Detected in all" HPA019654 Approved Approved Vesicles NA NA 69200 "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 18: U-2197 - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA019654: AB_1859050" "unprognostic (1.88e-1)" "unprognostic (2.64e-3)" "unprognostic (1.01e-2)" "unprognostic (4.37e-2)" "unprognostic (1.52e-1)" "unprognostic (5.91e-2)" "unprognostic (1.63e-1)" "unprognostic (9.24e-2)" "unprognostic (5.87e-2)" "unprognostic (1.63e-1)" "unprognostic (8.25e-4)" "unprognostic (5.42e-2)" "unprognostic (8.50e-2)" "unprognostic (1.02e-1)" "unprognostic (1.91e-1)" "unprognostic (9.50e-2)" "unprognostic (9.67e-2)" 0.9 0.5 1.2 0.6 3.0 6.9 0.7 2.9 2.4 0.2 1.2 0.6 0.9 0.2 0.9 0.6 4.7 0.5 1.6 1.1 2.0 0.6 0.8 0.6 0.5 5.8 3.6 0.2 0.5 0.4 0.4 0.4 3.9 0.3 0.8 0.8 1.1 0.3 3.2 0.9 0.7 0.4 3.4 0.4 0.4 0.6 2.2 0.7 0.6 1.8 0.4 0.4 0.3 7.7 1.3 0.5 2.1 2.2 0.6 0.2 1.1 0.9 1.4 1.0 0.7 1.9 1.8 2.8 0.7 1.4 1.1 2.4 2.3 2.5 2.0 1.9 1.3 1.4 3.1 1.0 0.3 2.2 2.5 0.6 0.8 3.2 1.0 0.4 1.0 1.9 2.2 0.6 1.3 0.5 2.1 2.1 1.3 1.0 1.0 1.3 1.4 2.0 1.2 1.6 0.9 2.6 1.4 1.5 3.7 1.5 1.8 1.6 0.7 1.5 1.1 7.9 2.6 1.4 3.3 2.3 4.0 1.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 3.0 2.9 2.4 1.1 2.0 5.8 3.6 3.9 3.4 2.2 7.7 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.1 COCH "COCH-5B2, DFNA31, DFNA9" ENSG00000100473 Cochlin O43405 14 30874514-30895065 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "pancreas: 502.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 63.0;Horizontal cells: 84.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 71.3" "Group enriched" "Detected in some" 12 "memory B-cell: 38.3;naive B-cell: 17.7" "Lineage enriched" "Detected in many" 17 "B-cells: 38.3" "Cell line enhanced" "Detected in many" "HEK 293: 95.7;Hep G2: 63.8;K-562: 129.1;NB-4: 105.5;SCLC-21H: 111.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 50.8" HPA065086 Supported Vesicles "Secreted in other tissues" NA NA 160000 "Cluster 19: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 1: K-562 - Erythropoiesis" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA065086: " "unprognostic (8.36e-3)" "unprognostic (2.51e-2)" "unprognostic (8.61e-2)" "unprognostic (1.64e-2)" "unprognostic (6.48e-2)" "unprognostic (6.53e-2)" "unprognostic (9.61e-2)" "unprognostic (4.03e-1)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" "unprognostic (1.27e-2)" "unprognostic (2.91e-3)" "unprognostic (5.42e-3)" "unprognostic (3.92e-2)" "unprognostic (2.80e-2)" "unprognostic (1.03e-1)" "unprognostic (1.72e-1)" 3.2 3.7 7.3 2.8 71.3 4.0 3.4 1.4 20.9 17.4 19.0 3.2 0.8 0.6 2.2 0.9 6.2 2.9 1.9 5.6 8.0 5.2 0.5 0.6 11.0 2.9 7.9 0.8 502.0 3.4 10.1 1.9 3.7 48.3 2.2 12.1 3.6 73.4 1.3 15.2 2.6 1.1 6.2 2.6 1.7 5.2 12.5 1.3 1.3 5.0 7.7 2.0 23.0 1.7 0.0 35.3 3.1 0.0 0.6 0.1 21.8 0.2 0.0 6.4 17.1 20.9 1.2 0.4 1.7 0.0 1.3 0.1 22.2 0.0 10.6 0.0 95.7 18.1 7.6 63.8 0.0 1.8 7.3 1.3 0.0 0.6 0.0 0.0 0.3 39.9 129.1 5.1 1.6 0.8 9.2 105.5 11.9 0.1 3.7 26.7 0.0 0.9 1.1 3.4 111.8 30.4 2.6 0.6 0.2 12.1 0.0 48.7 0.9 0.0 0.0 0.3 0.1 5.7 15.8 11.2 0.0 0.0 4.7 0.0 0.6 0.0 0.0 0.0 0.0 38.3 0.3 0.0 0.1 17.7 0.0 0.1 0.2 0.0 0.0 0.0 2.2 1.0 7.3 71.3 1.4 20.9 5.6 8.0 2.9 7.9 3.7 6.2 12.5 1.7 2.0 0.0 0.5 3.6 13.4 19.1 2.3 0.3 0.0 2.7 7.9 1.5 0.8 2.8 0.9 0.0 4.2 6.5 1.3 0.6 1.9 0.5 1.5 2.2 0.8 3.1 17.0 7.4 14.3 63.0 14.3 22.0 1.1 1.0 1.3 1.8 5.0 5.0 3.8 84.1 24.2 0.3 6.1 5.0 25.2 2.0 1.5 2.4 19.6 7.5 2.8 14.5 0.0 6.0 16.5 3.7 4.3 6.0 10.0 3.5 0.2 11.7 0.5 4.0 0.0 2.8 9.0 22.1 20.3 0.1 13.5 6.6 3.3 0.1 0.6 1.7 COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;Endometrial stromal cells: 97.0;Fibroblasts: 235.9;Smooth muscle cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 54.4;hTERT-RPE1: 29.7;RH-30: 123.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" 69.0 16.2 1.6 42.2 1.9 0.3 58.8 1.5 2.4 205.8 2.9 39.8 7.7 78.2 35.2 50.2 46.2 142.2 45.4 1.5 2.0 32.1 19.5 27.7 12.8 3.4 2.2 83.2 15.7 6.0 4.0 152.7 2.7 43.8 53.9 0.6 13.5 24.9 7.0 13.3 35.3 147.6 3.1 28.4 25.6 5.5 2.4 5.3 43.2 36.1 16.5 108.5 93.0 3.0 0.0 0.0 0.9 0.0 5.4 54.4 0.1 0.1 6.7 0.2 0.1 0.0 0.0 0.6 1.8 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 1.8 0.0 13.2 0.2 0.2 14.4 0.3 2.6 0.0 29.7 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.4 4.2 0.0 0.0 0.0 123.4 0.2 4.8 0.0 0.5 0.2 0.1 0.1 0.1 3.2 0.0 0.1 0.0 1.3 0.3 0.2 2.9 0.4 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.5 2.4 1.5 2.0 3.4 2.2 2.7 3.1 2.4 3.0 8.0 0.0 1.1 0.0 0.1 11.3 0.4 2.1 75.1 0.1 1.8 25.3 13.2 0.0 4.3 1.8 0.0 34.4 0.3 0.0 0.0 0.0 1.0 6.9 97.0 7.8 0.0 0.0 5.6 0.0 4.0 235.9 6.1 11.3 3.8 0.2 18.5 0.0 6.2 0.0 5.2 0.0 0.0 0.0 18.5 1.4 14.6 1.7 5.4 5.6 0.0 0.1 0.0 1.0 3.3 0.0 0.0 15.4 0.5 0.6 0.0 0.0 0.1 0.5 0.0 4.2 118.2 4.4 2.8 3.9 9.7 25.3 2.7 4.5 0.0 0.3 COL26A1 "EMI6, EMID2, Emu2" ENSG00000160963 "Collagen type XXVI alpha 1 chain" Q96A83 7 101362875-101559024 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;liver: 5.5" "Group enriched" "Detected in some" 7 "Excitatory neurons: 68.4;Inhibitory neurons: 18.5" "Group enriched" "Detected in many" 6 "endometrial cancer: 12.6;ovarian cancer: 5.7;prostate cancer: 4.6;testis cancer: 14.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 45 "plasmacytoid DC: 9.2" "Lineage enriched" "Detected in single" 45 "dendritic cells: 9.2" "Cell line enhanced" "Detected in some" "AF22: 30.0;BEWO: 23.9;HAP1: 10.7;NTERA-2: 25.4;SuSa: 19.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA027059 Approved Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA027059: AB_1848142" "unprognostic (5.94e-3)" "unprognostic (2.16e-2)" "unprognostic (2.19e-2)" "unprognostic (4.67e-2)" "unprognostic (1.66e-1)" "unprognostic (3.35e-1)" "prognostic favorable (2.32e-5)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.26e-3)" "unprognostic (1.78e-1)" "unprognostic (4.24e-3)" "unprognostic (3.60e-1)" "unprognostic (1.50e-1)" "unprognostic (7.48e-4)" "unprognostic (2.83e-3)" 0.1 4.4 5.2 0.1 7.4 0.2 0.1 0.2 12.8 0.2 0.2 0.0 0.0 0.3 0.1 0.0 0.3 0.1 0.0 9.8 1.2 4.9 5.5 0.4 0.5 1.1 0.9 0.4 2.2 3.9 0.9 0.3 0.9 2.2 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.4 0.2 0.3 1.0 2.0 1.2 0.1 0.0 0.1 0.2 0.1 4.2 0.0 0.8 30.0 1.9 0.0 0.0 23.9 0.0 0.0 0.0 0.0 1.3 0.0 0.1 4.7 0.0 0.1 0.0 10.7 0.0 0.0 1.0 1.3 0.0 0.0 7.9 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 25.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.6 0.0 0.0 0.2 19.2 0.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 5.2 7.4 0.2 12.8 9.8 1.2 1.1 0.9 0.9 0.4 2.0 4.2 0.0 0.0 0.0 3.3 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 5.5 0.0 0.3 0.0 0.0 0.0 0.2 1.5 0.1 1.7 0.1 0.0 0.0 68.4 0.6 0.4 0.5 0.0 0.2 0.0 1.0 0.0 3.6 0.1 0.0 18.5 0.0 0.0 0.0 0.0 3.5 0.0 0.5 0.0 5.6 0.0 0.0 0.0 3.5 2.1 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 2.0 0.0 0.0 0.4 0.0 0.9 0.0 0.4 COL4A2 "DKFZp686I14213, FLJ22259" ENSG00000134871 "Collagen type IV alpha 2 chain" P08572 13 110305812-110513209 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 474.0" "Cell type enhanced" "Detected in many" "Adipocytes: 313.6;Endometrial stromal cells: 308.3;Endothelial cells: 278.2;Extravillous trophoblasts: 512.9;Granulosa cells: 223.8;Sertoli cells: 374.7;Smooth muscle cells: 338.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 1041.3;WM-115: 428.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010751, HPA029118, HPA069337" Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA 2700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB010751: AB_476828, HPA029118: , HPA069337: " "unprognostic (2.43e-1)" "unprognostic (4.13e-3)" "unprognostic (8.04e-2)" "unprognostic (6.03e-3)" "unprognostic (2.20e-1)" "unprognostic (2.64e-2)" "unprognostic (3.45e-2)" "unprognostic (1.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.33e-2)" "unprognostic (1.57e-2)" "unprognostic (6.95e-2)" "prognostic unfavorable (9.25e-4)" 240.5 51.2 15.1 103.5 2.3 0.6 153.5 1.7 5.9 111.6 3.4 282.0 29.5 219.4 10.4 51.8 122.9 84.2 113.0 19.3 1.8 71.7 19.1 181.7 22.8 4.3 7.8 51.9 32.6 25.6 17.5 474.0 6.0 121.3 18.9 2.8 35.0 95.8 44.7 45.2 84.1 226.8 2.6 121.5 96.4 15.7 11.5 7.9 74.9 21.5 7.1 186.2 74.4 2.9 88.9 45.7 218.7 0.6 213.7 99.0 312.8 307.9 97.4 167.3 76.1 2.5 0.7 0.6 1041.3 60.0 75.0 85.4 0.1 82.4 27.3 28.1 46.3 0.2 76.6 0.7 150.5 0.5 1.0 42.8 4.5 114.8 71.2 193.5 158.5 0.0 1.3 0.9 25.4 0.3 0.3 12.1 34.2 0.8 11.7 0.6 87.8 0.4 125.6 0.0 6.4 35.4 0.3 0.9 81.2 84.7 0.6 6.7 327.7 94.9 237.9 2.3 161.9 0.6 3.0 7.4 5.8 0.4 428.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 2.3 1.7 5.9 19.3 1.8 4.3 7.8 6.0 2.6 11.5 2.9 313.6 83.3 5.8 17.9 2.9 9.6 8.0 16.3 1.8 2.4 7.0 56.8 31.8 20.0 1.8 53.3 0.0 77.4 0.1 10.0 1.9 39.0 1.7 19.4 308.3 278.2 0.0 8.0 17.7 4.4 512.9 159.1 5.6 50.1 1.3 223.8 102.1 1.8 30.9 0.0 44.0 7.0 2.0 3.3 13.3 3.4 60.6 3.8 39.2 46.9 2.0 7.3 0.0 5.5 1.1 2.8 1.4 176.0 1.5 12.3 23.9 32.7 2.1 0.3 374.7 64.7 338.9 0.9 8.5 0.7 7.0 67.2 3.6 49.4 5.4 2.4 COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.1;Fibroblasts: 134.9;Leydig cells: 61.2;Sertoli cells: 52.6;Skeletal myocytes: 78.3;Smooth muscle cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 446.6;fHDF/TERT166: 414.6;HeLa: 297.0;HHSteC: 265.8;SiHa: 290.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" 39.3 12.0 1.3 39.1 1.5 1.0 20.0 1.9 2.7 146.6 3.4 72.0 13.5 118.2 11.1 23.2 59.6 77.6 32.8 1.2 1.9 11.5 7.6 35.7 5.5 4.0 2.5 51.9 7.0 6.8 6.6 95.8 1.3 43.8 16.3 3.1 9.3 28.9 10.2 24.6 22.0 89.6 1.8 17.6 31.4 6.2 4.6 2.3 10.1 7.3 2.9 51.6 63.4 1.4 0.6 16.7 13.0 20.7 192.2 202.4 7.9 446.6 89.0 73.6 78.6 0.2 0.3 0.0 95.3 414.6 39.8 5.6 0.0 0.1 21.3 0.1 1.0 0.3 297.0 0.1 265.8 0.2 2.7 200.0 0.2 71.1 5.6 0.0 89.2 0.1 0.1 1.2 39.5 4.1 0.3 0.9 7.6 0.0 8.5 15.7 50.3 1.8 0.1 0.1 5.3 2.5 290.0 1.8 0.2 173.7 0.6 0.2 152.6 154.4 61.9 190.4 93.7 0.3 0.2 0.4 121.6 0.1 26.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 2.7 1.2 1.9 4.0 2.5 1.3 1.8 4.6 1.4 7.9 0.0 1.8 0.7 0.3 14.5 3.5 0.8 3.4 8.5 0.8 2.7 9.0 0.0 0.0 1.8 2.1 6.4 0.3 0.0 1.9 2.2 5.5 4.2 141.1 8.8 0.0 0.0 6.6 0.0 12.3 134.9 1.5 4.8 0.0 1.2 21.8 0.0 8.9 0.0 1.2 0.0 0.0 0.3 15.3 15.6 61.2 1.5 7.2 12.2 0.0 6.4 0.0 5.5 0.3 1.3 0.0 38.7 0.3 1.0 0.0 0.3 0.0 1.2 52.6 78.3 57.5 0.5 0.8 0.6 7.7 10.4 2.6 11.7 0.0 0.4 COL8A1 "C3orf7, MGC9568" ENSG00000144810 "Collagen type VIII alpha 1 chain" P27658 3 99638475-99799226 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Fibroblasts: 53.3;Hepatic stellate cells: 102.8;Smooth muscle cells: 51.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 34.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 1098.3;hTERT-RPE1: 431.9;LHCN-M2: 313.0;TIME: 471.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053107 Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA053107: AB_2682046" "unprognostic (3.13e-2)" "unprognostic (2.92e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-3)" "unprognostic (2.49e-1)" "unprognostic (2.31e-2)" "unprognostic (4.83e-2)" "unprognostic (2.62e-2)" "unprognostic (4.79e-2)" "unprognostic (3.58e-2)" "unprognostic (3.71e-1)" "prognostic unfavorable (9.39e-8)" "unprognostic (2.98e-3)" "unprognostic (1.72e-1)" "unprognostic (1.38e-2)" "unprognostic (1.32e-3)" 33.0 7.0 1.7 5.8 2.9 0.0 5.7 1.8 2.6 3.8 4.4 12.4 1.0 5.2 2.7 11.1 9.1 10.8 39.1 1.3 3.0 5.9 0.9 32.8 0.9 3.1 3.9 9.2 1.2 17.9 11.3 4.2 3.4 12.7 6.9 0.5 7.0 12.0 2.3 3.2 3.7 31.5 2.7 1.0 5.3 0.5 2.6 0.4 27.5 7.8 0.5 25.0 5.4 2.5 0.1 0.4 3.0 0.3 142.2 236.4 0.2 68.5 45.7 69.6 138.6 0.0 0.3 0.1 5.9 1098.3 1.9 0.1 0.4 88.2 157.8 0.1 0.2 0.1 7.9 0.0 26.8 0.0 0.1 142.8 3.2 52.6 82.9 431.9 129.4 0.0 0.1 0.2 313.0 0.0 0.0 0.0 2.6 0.0 0.9 0.0 0.0 0.0 144.3 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.1 0.2 471.5 31.0 24.1 1.6 34.2 0.1 0.0 0.1 58.4 0.0 241.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.9 1.8 2.6 1.3 3.0 3.1 3.9 3.4 2.7 2.6 2.5 4.4 246.8 22.1 0.0 0.4 0.8 0.5 2.8 14.8 0.4 1.8 5.2 4.9 4.3 3.9 9.2 0.0 0.1 0.9 0.0 0.0 0.1 1.3 0.2 2.6 14.1 0.0 0.0 1.9 0.0 0.3 53.3 2.0 0.3 5.1 0.2 102.8 0.8 0.1 0.0 0.7 0.0 0.0 1.9 2.3 1.0 2.1 0.8 1.8 4.7 0.2 0.7 2.1 9.0 0.6 0.1 0.0 9.4 0.5 0.2 0.0 1.6 1.0 0.6 0.0 1.9 51.6 0.3 0.3 1.0 0.6 0.4 0.9 0.1 0.0 0.5 COLGALT1 "FLJ22329, GLT25D1" ENSG00000130309 "Collagen beta(1-O)galactosyltransferase 1" Q8NBJ5 19 17555649-17583162 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 76.2;Hofbauer cells: 91.0;Kupffer cells: 70.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047821 Approved Approved Vesicles "Intracellular and membrane" No No 9700 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA047821: AB_2680168" "unprognostic (2.46e-1)" "unprognostic (1.16e-1)" "unprognostic (3.49e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.65e-5)" "unprognostic (2.92e-3)" "unprognostic (2.92e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.43e-2)" "unprognostic (1.09e-1)" "unprognostic (8.87e-2)" "prognostic unfavorable (3.83e-4)" 38.6 14.3 5.9 38.1 6.9 32.9 27.5 7.9 8.4 31.1 10.6 27.7 16.2 28.4 4.4 17.9 26.5 19.0 22.4 7.1 9.1 12.7 16.3 34.9 29.7 12.1 9.3 23.5 15.8 9.0 10.1 40.9 12.3 15.5 15.2 3.2 15.9 16.3 15.1 23.9 24.7 35.4 7.6 39.5 18.2 11.9 18.9 9.9 14.7 7.5 15.8 28.1 22.8 12.6 103.1 118.0 56.7 79.8 222.3 136.3 90.9 95.9 55.1 121.8 125.9 90.4 159.6 53.0 164.7 166.9 104.2 91.5 58.4 110.6 73.4 29.5 94.9 51.2 147.4 87.9 121.6 123.0 147.8 115.2 97.6 136.7 56.7 49.7 138.8 33.3 105.5 25.8 45.1 45.6 61.9 81.1 43.0 75.8 115.3 65.2 73.8 80.9 26.4 67.2 41.2 29.9 102.8 80.6 97.0 36.7 41.9 177.7 98.7 240.8 67.7 215.3 156.2 45.4 125.1 58.3 142.7 232.4 113.0 1.7 25.7 12.5 5.2 28.1 2.8 3.5 4.8 4.9 18.1 3.3 3.4 5.3 3.6 2.1 20.8 7.0 3.1 14.5 5.9 6.9 7.9 8.4 7.1 9.1 12.1 9.3 12.3 7.6 18.9 12.6 35.0 19.2 23.5 11.1 10.3 19.5 7.0 10.4 10.8 3.7 8.8 9.5 11.2 10.0 15.5 11.0 6.2 7.9 28.6 14.7 0.0 13.1 3.6 8.5 28.5 29.3 5.4 10.3 10.9 8.2 76.2 30.9 20.9 13.6 8.8 20.3 7.9 14.2 91.0 13.5 9.9 15.1 4.1 70.7 24.1 3.1 19.0 59.6 17.8 19.7 26.6 2.3 10.3 6.6 12.8 10.4 7.6 21.8 6.0 9.5 9.5 4.4 8.7 3.6 13.1 9.5 24.3 2.5 13.1 13.8 20.9 8.3 12.0 24.9 18.2 8.4 COMMD7 "C20orf92, dJ1085F17.3" ENSG00000149600 "COMM domain containing 7" Q86VX2 20 32702699-32743467 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 225.9;Syncytiotrophoblasts: 264.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 331.1" "Low region specificity" "Detected in all" HPA054119 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "HPA054119: AB_2682388" "unprognostic (1.27e-1)" "unprognostic (1.51e-1)" "unprognostic (1.65e-1)" "unprognostic (1.84e-1)" "unprognostic (9.90e-2)" "unprognostic (1.64e-2)" "prognostic unfavorable (1.46e-4)" "unprognostic (5.31e-2)" "unprognostic (8.92e-2)" "unprognostic (2.31e-1)" "unprognostic (6.57e-2)" "unprognostic (2.98e-1)" "unprognostic (2.90e-3)" "unprognostic (5.04e-2)" "unprognostic (8.28e-2)" "unprognostic (8.52e-2)" "prognostic favorable (3.53e-4)" 34.6 38.7 60.2 23.0 62.5 40.5 36.6 59.3 87.1 27.9 58.6 41.4 18.1 29.1 49.1 27.2 27.3 25.7 61.7 62.2 59.7 52.7 44.5 29.4 29.9 59.4 62.5 24.1 36.7 40.7 17.7 38.5 59.1 35.6 30.3 24.7 31.7 31.2 66.4 37.1 26.4 33.2 58.9 36.8 36.0 11.5 61.9 25.8 49.7 54.4 34.0 38.3 28.3 58.8 69.9 45.2 43.6 30.9 32.4 58.7 80.3 59.8 96.8 96.4 66.0 88.0 44.0 55.3 51.1 71.4 80.3 30.6 38.0 49.7 72.0 22.3 25.2 154.8 25.3 65.6 83.6 63.5 84.2 45.6 61.1 73.9 43.3 76.1 95.9 30.1 55.8 26.7 62.4 51.4 55.4 133.2 37.4 68.6 43.9 51.4 4.2 19.0 103.2 46.6 26.8 41.3 59.1 81.6 101.3 47.5 48.3 101.6 65.3 97.3 54.0 61.8 61.3 29.8 25.6 18.6 119.0 331.1 39.6 116.9 105.8 162.7 76.5 144.0 67.7 63.5 61.4 70.9 122.7 61.2 67.7 64.6 10.4 99.9 165.2 82.2 75.1 166.2 60.2 62.5 59.3 87.1 62.2 59.7 59.4 62.5 59.1 58.9 61.9 58.8 71.3 22.4 17.9 10.1 43.2 16.6 31.4 44.4 23.9 56.8 58.7 50.2 48.3 47.1 32.1 36.8 68.8 225.9 70.5 33.6 88.0 102.8 3.1 27.7 25.8 54.8 33.0 36.6 19.6 118.5 116.5 36.8 31.1 31.1 53.3 49.2 44.3 39.8 124.3 67.3 25.4 44.4 59.0 46.4 30.9 4.6 37.6 69.6 56.9 16.9 92.7 81.8 123.6 4.5 10.3 118.7 47.0 47.8 35.3 32.8 27.6 124.3 23.3 74.3 46.0 27.0 49.3 13.1 19.1 36.8 28.8 264.5 75.6 36.9 45.8 37.9 CPLX1 CPX-I ENSG00000168993 "Complexin 1" O14810 4 784957-826129 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 273.5" "Cell type enhanced" "Detected in many" "Adipocytes: 45.5;Bipolar cells: 33.4;Endothelial cells: 29.6;Excitatory neurons: 44.2;Inhibitory neurons: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 84.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071191, HPA074390" Supported Uncertain Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA071191: , HPA074390: " "unprognostic (9.21e-3)" "prognostic unfavorable (4.20e-4)" "unprognostic (3.45e-2)" "unprognostic (4.68e-2)" "unprognostic (1.16e-2)" "unprognostic (1.02e-1)" "unprognostic (3.14e-2)" "unprognostic (2.26e-2)" "unprognostic (9.52e-3)" "unprognostic (2.01e-2)" "prognostic favorable (5.05e-4)" "unprognostic (1.10e-3)" "unprognostic (3.32e-1)" "unprognostic (2.05e-2)" "unprognostic (1.12e-1)" "unprognostic (1.34e-1)" "unprognostic (7.77e-2)" 17.2 13.4 26.1 1.2 43.0 0.1 18.2 59.7 273.5 16.9 0.0 5.0 1.0 10.8 0.1 5.7 16.4 0.4 11.5 18.5 72.8 10.9 8.3 9.4 0.8 135.5 25.1 9.4 3.2 1.4 12.8 0.3 128.2 13.8 0.2 5.7 9.6 0.7 4.1 3.4 5.1 0.4 13.9 27.2 4.9 8.6 124.2 3.6 7.5 0.2 0.2 8.3 12.9 89.9 5.7 0.5 0.1 0.8 0.0 0.0 0.3 0.2 0.0 0.0 0.0 16.3 1.7 4.2 1.9 0.0 0.3 0.0 0.4 0.0 0.0 0.0 1.8 0.4 0.0 1.8 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 2.3 2.0 0.3 0.0 2.5 2.3 0.0 2.6 4.4 2.6 0.1 0.0 1.6 0.0 0.4 84.3 11.8 0.4 5.5 0.0 0.2 8.5 0.3 0.1 0.0 0.5 0.1 0.1 0.2 4.7 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 26.1 43.0 59.7 273.5 18.5 72.8 135.5 25.1 128.2 13.9 124.2 89.9 45.5 0.0 0.0 5.9 0.4 1.0 3.2 0.4 1.8 33.4 7.8 8.1 3.6 0.0 1.9 0.0 4.2 0.1 2.8 2.5 1.9 1.2 1.4 1.1 5.4 29.6 21.5 0.0 44.2 0.8 3.2 1.8 2.6 1.4 0.0 0.3 14.3 4.8 0.2 18.5 90.7 2.1 0.0 0.3 1.9 2.3 1.8 0.5 1.8 8.4 0.0 16.8 0.0 8.0 4.7 0.8 5.2 0.0 0.6 2.6 0.3 1.2 0.0 21.7 0.0 0.4 2.3 4.3 9.8 0.2 1.1 1.0 1.6 0.8 2.7 1.3 CPLX2 "CPX-2, DKFZp547D155" ENSG00000145920 "Complexin 2" Q6PUV4 5 175796310-175884021 "Predicted intracellular proteins" "Differentiation, Exocytosis, Mast cell degranulation, Neurogenesis, Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 308.9;epididymis: 128.6;pituitary gland: 65.6" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 36.6;Excitatory neurons: 44.7;Horizontal cells: 95.9;Inhibitory neurons: 35.9;Late spermatids: 32.9" "Cancer enhanced" "Detected in many" "liver cancer: 9.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "A549: 496.4;Hep G2: 323.4;SCLC-21H: 201.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071191, HPA074390" Supported Uncertain Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA071191: , HPA074390: " "unprognostic (1.36e-1)" "unprognostic (1.12e-1)" "unprognostic (2.81e-1)" "unprognostic (8.98e-2)" "unprognostic (1.23e-2)" "unprognostic (5.73e-2)" "unprognostic (5.16e-2)" "unprognostic (2.49e-3)" "unprognostic (6.22e-2)" "unprognostic (1.20e-2)" "unprognostic (2.06e-1)" "unprognostic (1.90e-5)" "unprognostic (6.88e-2)" "unprognostic (2.20e-1)" "unprognostic (7.32e-2)" "unprognostic (6.87e-2)" 0.7 28.3 239.7 1.0 136.0 0.0 0.1 78.2 291.5 0.0 0.0 3.5 2.1 0.0 128.6 0.1 0.0 0.0 0.2 308.9 62.3 0.1 0.2 1.3 0.0 62.2 98.8 0.2 9.0 0.1 65.6 0.0 50.2 0.2 1.4 19.4 0.1 0.0 0.2 0.1 1.6 0.3 0.0 0.0 5.0 3.0 19.6 0.1 0.2 0.0 0.0 0.1 0.5 157.7 0.0 496.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 323.4 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.1 0.3 2.1 15.2 0.1 0.0 0.0 0.6 0.0 0.2 201.3 16.3 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 239.7 136.0 78.2 291.5 308.9 62.3 62.2 98.8 50.2 0.0 19.6 157.7 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.2 36.6 0.0 44.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.9 35.9 1.0 0.0 0.0 0.0 32.9 0.9 0.0 0.0 4.7 0.0 1.1 0.0 5.5 3.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 156.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 359.0;Alveolar cells type 2: 362.2;Kupffer cells: 368.5;Sertoli cells: 762.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 21.0;intermediate monocyte: 14.5;myeloid DC: 16.6;non-classical monocyte: 7.4" "Group enriched" "Detected in many" 5 "dendritic cells: 16.6;monocytes: 21.0" "Group enriched" "Detected in many" 4 "ASC diff: 71.1;ASC TERT1: 50.0;HSkMC: 91.2;SiHa: 68.9;THP-1: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 7100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" 156.1 11.5 6.4 14.4 13.3 3.5 40.2 10.1 10.5 14.4 3.8 33.5 4.4 23.9 0.9 10.1 16.2 16.1 4.6 7.6 10.2 41.3 26.5 59.3 16.1 19.3 11.5 18.0 13.0 12.0 1.0 70.1 11.9 14.7 26.6 6.7 4.1 2.8 5.8 21.7 5.9 6.4 7.5 19.4 15.3 5.4 28.0 4.3 7.5 9.7 10.5 9.3 5.7 23.5 0.1 4.0 0.1 0.0 71.1 50.0 0.7 9.8 1.1 1.7 2.3 3.2 4.1 0.5 9.6 1.4 4.1 0.0 1.4 2.7 4.1 0.1 2.7 0.0 15.1 0.3 0.4 1.2 1.9 91.2 0.6 1.0 2.0 8.6 0.0 0.3 0.0 0.1 7.3 1.7 0.0 0.7 1.7 0.0 5.2 3.1 0.6 0.0 7.2 5.9 0.4 0.2 68.9 10.7 7.9 5.5 1.2 26.5 0.2 1.2 7.5 0.5 0.2 0.4 0.5 13.1 4.3 13.1 5.9 0.6 21.0 0.1 0.2 14.5 0.0 1.8 1.5 0.1 16.6 3.5 0.9 0.2 1.6 0.5 7.4 1.1 1.9 7.3 6.4 13.3 10.1 10.5 7.6 10.2 19.3 11.5 11.9 7.5 28.0 23.5 83.3 359.0 362.2 34.6 4.9 12.4 3.5 6.1 0.6 3.3 7.8 8.9 2.6 135.8 70.1 51.5 0.0 32.3 1.1 97.5 29.4 57.9 16.6 100.9 8.3 29.0 10.8 3.6 1.2 212.5 59.9 14.1 4.6 237.1 112.5 6.7 73.9 36.6 134.6 0.0 1.3 28.7 0.0 368.5 36.3 17.5 105.0 202.2 10.6 19.7 23.3 68.9 1.0 23.1 161.8 68.0 65.9 79.0 2.4 38.7 1.9 63.7 16.4 5.7 762.6 7.2 126.9 0.6 3.9 2.4 9.9 172.4 14.5 46.3 32.7 2.8 CRB1 "LCA8, RP12" ENSG00000134376 "Crumbs cell polarity complex component 1" P82279 1 197268204-197478455 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.3;retina: 74.7" "Cell type enhanced" "Detected in some" "Astrocytes: 469.5;Cone photoreceptor cells: 164.7;Inhibitory neurons: 130.1;Muller glia cells: 79.7;Oligodendrocyte precursor cells: 280.0;Oligodendrocytes: 105.6;Rod photoreceptor cells: 149.3" "Cancer enriched" "Detected in single" 12 "glioma: 2.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "basophil: 7.7" "Lineage enriched" "Detected in single" 28 "granulocytes: 7.7" "Cell line enriched" "Detected in some" 8 "HeLa: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA061250, HPA063127" Approved Uncertain Vesicles "Secreted in brain" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA061250: AB_2684458, HPA063127: AB_2684944" "unprognostic (1.96e-1)" "unprognostic (5.38e-3)" "unprognostic (2.92e-3)" "unprognostic (1.50e-2)" "unprognostic (5.13e-1)" "unprognostic (3.28e-2)" "unprognostic (2.38e-1)" "unprognostic (2.49e-2)" "unprognostic (1.05e-1)" "unprognostic (1.48e-3)" "unprognostic (2.59e-1)" "unprognostic (2.01e-3)" "unprognostic (1.78e-3)" "unprognostic (1.56e-1)" "unprognostic (3.36e-2)" "unprognostic (2.96e-1)" 0.1 0.1 15.7 0.0 17.6 0.4 0.1 19.8 20.5 0.0 9.6 0.1 0.0 0.0 0.1 0.1 0.4 0.0 0.2 15.8 14.2 0.1 0.0 0.1 0.1 18.7 18.4 0.7 0.4 0.0 2.2 0.0 17.5 0.0 0.0 74.7 0.0 0.0 0.7 0.0 0.0 0.0 18.9 0.0 0.2 2.9 16.1 0.0 0.2 0.5 0.0 0.0 0.0 21.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 15.7 17.6 19.8 20.5 15.8 14.2 18.7 18.4 17.5 18.9 16.1 21.3 0.0 0.0 0.0 469.5 0.0 0.3 0.2 0.3 0.0 15.0 0.2 0.1 1.1 0.0 0.2 0.0 164.7 0.0 0.0 0.0 0.0 0.0 1.9 0.2 0.0 0.7 0.0 11.6 53.2 0.0 0.0 0.2 0.0 0.0 0.0 6.4 0.0 0.0 0.0 1.7 130.1 0.0 2.0 0.0 0.5 1.6 1.8 0.0 0.0 24.4 0.0 79.7 0.0 280.0 105.6 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.9 149.3 0.0 0.2 0.1 1.8 0.3 0.0 0.3 0.0 0.1 0.2 0.0 0.0 CROT COT ENSG00000005469 "Carnitine O-octanoyltransferase" Q9UKG9 7 87345664-87399794 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 136.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 71.7;RT4: 72.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019052, HPA019364, HPA019365" Enhanced Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "HPA019052: AB_1847172, HPA019364: AB_1847173, HPA019365: AB_1847174" "unprognostic (2.80e-2)" "unprognostic (6.47e-2)" "unprognostic (1.75e-1)" "unprognostic (4.56e-2)" "unprognostic (1.70e-1)" "unprognostic (2.55e-2)" "unprognostic (1.84e-1)" "unprognostic (9.93e-3)" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" "unprognostic (9.84e-2)" "unprognostic (3.48e-1)" "prognostic favorable (2.55e-6)" "unprognostic (3.52e-2)" "unprognostic (1.34e-1)" "unprognostic (7.60e-3)" "prognostic favorable (4.02e-4)" 5.4 10.5 4.8 6.3 6.1 3.2 16.1 5.9 6.1 11.8 7.9 12.6 31.9 7.8 18.5 19.3 10.7 14.1 6.6 5.7 5.1 16.9 35.0 6.6 6.2 4.6 5.0 8.6 6.7 18.7 6.0 19.0 4.5 21.1 11.0 35.4 9.3 27.5 11.3 24.6 23.6 8.6 4.9 5.4 6.8 3.3 5.3 7.6 40.5 9.5 8.5 25.2 19.0 5.6 15.3 10.9 13.5 4.7 12.6 11.5 9.9 15.7 14.8 9.4 10.1 6.0 7.9 6.4 13.6 13.6 18.9 18.9 2.3 21.2 13.5 9.1 9.5 13.9 7.8 7.6 8.1 8.8 8.3 9.4 71.7 7.6 6.0 12.1 13.7 10.4 0.7 9.0 25.2 15.0 11.2 8.8 3.0 5.5 16.4 5.0 18.6 1.1 12.3 72.1 2.2 10.5 19.2 22.3 10.6 9.2 14.2 3.1 7.2 22.0 9.5 29.8 15.2 13.6 21.0 8.8 14.8 0.1 13.3 2.0 1.3 3.4 6.6 1.7 8.7 2.0 6.7 5.5 1.9 1.9 5.3 5.9 0.8 13.0 6.2 2.2 6.2 2.8 4.8 6.1 5.9 6.1 5.7 5.1 4.6 5.0 4.5 4.9 5.3 5.6 8.6 22.4 10.0 18.9 5.1 16.8 56.4 45.0 65.4 16.9 17.5 12.7 14.9 14.3 35.0 53.3 45.9 136.5 9.0 21.0 9.8 7.6 28.7 9.5 9.3 7.2 7.3 4.8 26.3 8.7 7.9 12.0 11.2 12.1 7.6 9.5 5.3 29.7 13.6 15.2 11.1 15.8 16.2 6.3 4.8 63.1 15.8 5.9 19.6 7.5 6.3 25.9 22.6 15.6 16.1 11.1 9.9 13.9 4.8 20.1 53.7 19.9 24.1 79.7 6.6 10.0 10.1 2.4 4.8 29.6 15.3 49.0 9.6 8.7 15.1 48.4 CSF2 "GM-CSF, GMCSF" ENSG00000164400 "Colony stimulating factor 2" P04141 5 132073789-132076170 "Cancer-related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lung: 2.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 11.4;Basal respiratory cells: 11.3;dendritic cells: 17.7;Ductal cells: 18.3;Pancreatic endocrine cells: 24.9;T-cells: 28.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "NK-cell: 6.2" "Lineage enriched" "Detected in single" 12 "NK-cells: 6.2" "Cell line enriched" "Detected in some" 4 "BJ hTERT+: 91.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA057404, HPA062006" Enhanced Vesicles "Secreted to blood" NA NA 23900 "Cluster 15: NK-cells - Transcription" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA057404: AB_2683428, HPA062006: AB_2684654" "unprognostic (7.29e-2)" "unprognostic (2.49e-3)" "unprognostic (8.77e-2)" "unprognostic (2.09e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" "unprognostic (2.56e-1)" "unprognostic (1.47e-2)" "unprognostic (2.64e-1)" "unprognostic (3.68e-3)" "unprognostic (1.87e-8)" "unprognostic (4.81e-2)" "unprognostic (1.22e-1)" "unprognostic (9.07e-2)" "unprognostic (2.06e-2)" 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 2.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 9.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 91.3 0.1 5.1 0.0 7.4 0.0 1.5 0.0 5.3 0.2 0.0 6.8 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 20.8 13.8 2.5 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.4 1.3 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.3 3.8 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.2 11.4 0.0 0.3 1.5 0.1 11.3 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.0 17.7 0.1 0.0 18.3 0.0 0.3 0.2 4.8 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.2 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.7 1.0 0.0 0.0 0.6 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.6 0.0 28.6 0.0 0.0 1.1 CSMD1 "KIAA1890, PPP1R24" ENSG00000183117 "CUB and Sushi multiple domains 1" Q96PZ7 8 2935353-4994972 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 10.7" "Group enriched" "Detected in some" 20 "Excitatory neurons: 4868.4;Inhibitory neurons: 3913.1;Oligodendrocyte precursor cells: 4521.8" "Cancer enhanced" "Detected in some" "testis cancer: 0.9" "Region enhanced" "Detected in many" "cerebral cortex: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 4.9;U-2 OS: 2.2;U-266/70: 2.2;U-266/84: 2.1;U-698: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074707 Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA074707: AB_2686707" "unprognostic (6.32e-2)" "unprognostic (4.23e-2)" "unprognostic (2.37e-1)" "unprognostic (1.67e-3)" "unprognostic (5.72e-2)" "unprognostic (4.26e-2)" "unprognostic (1.02e-2)" "unprognostic (4.66e-2)" "unprognostic (7.69e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-1)" "unprognostic (7.90e-2)" "unprognostic (1.01e-1)" "unprognostic (2.74e-2)" "unprognostic (5.09e-2)" "unprognostic (1.26e-2)" "unprognostic (1.11e-1)" 0.1 0.0 3.5 0.0 5.8 0.0 0.2 0.0 10.7 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 5.8 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.0 1.6 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.6 0.0 2.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.2 0.0 0.0 2.2 2.1 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 5.8 0.0 10.7 5.8 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.6 0.0 0.5 108.4 0.0 0.3 0.0 0.0 2.2 15.0 1.0 0.9 2.2 0.0 0.6 1.8 0.0 3.4 0.0 0.1 0.0 0.0 52.5 1.5 0.3 2.2 0.0 0.0 4868.4 0.0 1.3 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 3913.1 0.1 0.0 0.0 0.7 15.0 0.3 0.2 0.0 220.2 0.7 0.5 0.0 4521.8 135.2 0.0 0.1 0.4 0.0 0.0 0.0 1.2 9.7 0.6 0.0 0.2 0.5 10.2 5.3 1.0 0.1 3.6 0.1 2.8 0.0 0.1 CSNK1G2 CK1g2 ENSG00000133275 "Casein kinase 1 gamma 2" P78368 19 1941172-1981338 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 254.8;Late spermatids: 613.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034868, HPA056572" Uncertain Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA034868: AB_10671235, HPA056572: AB_2683178" "unprognostic (2.00e-1)" "unprognostic (2.15e-1)" "unprognostic (1.83e-1)" "unprognostic (2.42e-3)" "unprognostic (6.51e-3)" "unprognostic (2.27e-3)" "unprognostic (1.14e-3)" "unprognostic (2.00e-1)" "unprognostic (9.42e-2)" "unprognostic (5.78e-2)" "unprognostic (4.83e-3)" "unprognostic (4.09e-3)" "unprognostic (7.95e-2)" "unprognostic (4.65e-3)" "unprognostic (5.09e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-2)" 37.1 52.7 19.3 40.5 17.9 47.3 38.3 22.8 28.1 35.1 18.3 35.0 29.5 34.5 6.5 50.6 35.7 20.6 33.8 21.6 16.6 42.6 41.6 53.5 41.8 20.8 19.2 39.5 39.8 13.3 51.5 17.7 18.1 41.3 8.7 9.8 38.1 14.0 39.4 45.1 46.9 10.3 12.8 69.2 35.5 99.9 18.3 23.5 35.8 12.3 18.7 32.3 37.8 18.1 71.2 37.3 51.0 80.1 17.5 32.6 42.7 43.1 28.0 32.0 39.1 31.0 37.8 44.3 35.2 27.6 17.8 50.1 27.6 52.5 14.0 40.5 60.4 31.2 65.0 52.9 28.2 50.7 76.3 32.5 33.8 33.4 21.3 24.7 38.4 54.2 67.1 146.5 21.4 41.3 101.0 66.8 92.7 19.7 41.8 86.8 32.3 72.7 24.3 73.2 81.9 67.4 32.2 52.7 48.2 18.8 33.6 81.8 46.6 40.2 31.5 85.3 50.6 94.8 54.5 55.5 40.7 47.6 42.8 2.8 3.6 4.7 4.2 5.8 3.0 3.4 3.1 3.6 3.6 3.3 2.4 3.4 10.0 3.5 14.4 5.4 2.4 2.4 19.3 17.9 22.8 28.1 21.6 16.6 20.8 19.2 18.1 12.8 18.3 18.1 37.5 16.0 17.9 10.1 36.5 21.9 17.8 14.9 10.8 43.6 28.9 26.8 14.2 10.0 14.9 11.0 41.7 12.2 91.7 36.9 9.8 17.1 254.8 37.7 32.5 24.7 30.5 12.6 10.8 29.5 18.9 21.6 31.1 32.4 29.9 41.8 16.8 16.4 14.9 25.2 9.8 26.6 6.1 21.9 30.3 613.6 20.5 32.3 14.2 14.0 16.4 21.6 41.2 5.5 6.2 30.1 24.0 18.8 38.2 28.8 15.0 14.6 22.8 39.3 13.1 26.4 23.0 16.0 13.2 19.0 25.3 18.2 46.2 51.7 24.8 32.8 CT55 "CXorf48, FLJ20527" ENSG00000169551 "Cancer/testis antigen 55" Q8WUE5 X 135156540-135171398 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 3.8" "Group enriched" "Detected in some" 46 "Spermatocytes: 43.8;Spermatogonia: 57.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 15 "K-562: 7.6" HPA059575 Approved Vesicles "Secreted in male reproductive system" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA059575: " "unprognostic (6.20e-2)" "unprognostic (1.39e-1)" "unprognostic (8.36e-2)" "unprognostic (5.86e-3)" "unprognostic (3.47e-1)" "unprognostic (2.67e-1)" "unprognostic (4.44e-2)" "unprognostic (1.49e-1)" 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.8 57.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 CTSA "GSL, PPGB" ENSG00000064601 "Cathepsin A" P10619 20 45890144-45898824 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 368.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 445.6;Proximal enterocytes: 301.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 856.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024930, HPA031068, HPA072487" Enhanced Enhanced Vesicles "Intracellular and membrane" NA NA 28000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "CAB024930: , HPA031068: AB_10601205, HPA072487: " "unprognostic (8.61e-2)" "unprognostic (3.37e-1)" "unprognostic (4.30e-2)" "unprognostic (2.13e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (6.33e-2)" "unprognostic (9.53e-3)" "unprognostic (7.19e-2)" "unprognostic (1.83e-1)" "unprognostic (6.85e-2)" "unprognostic (7.57e-2)" "unprognostic (1.09e-1)" "unprognostic (6.05e-2)" "unprognostic (1.71e-1)" "unprognostic (8.40e-2)" 80.4 368.3 56.8 75.3 58.1 75.6 61.9 63.6 65.6 47.6 96.0 178.6 100.9 55.1 39.0 60.4 39.3 89.7 97.2 59.7 63.8 188.1 95.7 90.9 61.6 62.6 59.1 62.2 52.9 104.4 43.8 76.4 61.4 38.5 170.4 44.0 61.3 48.4 56.0 95.2 109.2 67.3 59.4 108.5 63.3 33.5 70.2 23.0 47.4 61.7 58.8 82.8 49.2 68.4 111.9 114.1 17.6 89.2 856.5 438.6 47.0 150.3 424.0 169.6 217.5 214.4 291.8 24.1 176.2 299.9 638.1 168.6 55.9 105.6 95.7 47.6 53.6 54.3 53.4 375.9 187.3 98.0 240.9 349.0 123.6 107.9 22.5 421.9 190.1 28.2 61.0 355.1 186.9 232.1 25.8 82.4 19.4 172.6 272.1 37.8 107.3 135.7 138.2 96.7 36.9 37.8 263.2 450.3 444.4 51.5 108.5 141.8 172.5 335.0 76.2 178.9 123.7 162.1 238.5 15.7 599.3 128.6 142.4 480.7 305.9 530.5 44.9 168.8 185.5 42.0 75.6 78.3 102.4 25.7 26.6 39.8 152.4 81.2 120.1 40.6 155.4 378.1 56.8 58.1 63.6 65.6 59.7 63.8 62.6 59.1 61.4 59.4 70.2 68.4 53.7 35.3 32.6 26.1 38.2 24.2 38.9 88.8 17.6 58.4 18.4 15.9 12.6 65.8 64.1 71.7 60.5 104.1 27.5 445.6 39.2 246.0 3.3 22.3 39.5 56.0 54.0 22.1 20.4 166.4 109.2 86.8 29.6 62.4 9.5 50.8 102.1 67.9 297.1 47.1 25.2 74.5 95.6 177.1 25.1 4.8 32.9 273.1 112.1 12.2 135.6 86.6 37.0 7.1 10.2 135.0 216.0 27.4 41.9 18.6 301.8 245.8 34.2 46.1 26.3 33.7 54.5 15.3 31.9 24.0 22.9 144.1 49.1 91.3 113.9 36.2 CTSC "DPP1, PALS, PLS" ENSG00000109861 "Cathepsin C" P53634 11 88265069-88359684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 900.7;Club cells: 471.8;Hofbauer cells: 1100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1078.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025364, HPA066610, HPA068434" Enhanced Supported Vesicles "Intracellular and membrane" No No 19000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB025364: , HPA066610: AB_2685694, HPA068434: AB_2685989" "unprognostic (4.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (1.10e-1)" "unprognostic (3.70e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (9.30e-5)" "unprognostic (1.62e-1)" "unprognostic (1.04e-1)" "unprognostic (1.56e-2)" "unprognostic (3.11e-2)" "unprognostic (3.35e-1)" "prognostic favorable (4.80e-4)" "unprognostic (2.93e-1)" "unprognostic (4.35e-2)" "unprognostic (8.10e-2)" "unprognostic (4.07e-2)" 173.2 60.7 9.9 185.1 9.6 71.7 63.4 11.1 24.9 77.9 14.2 143.1 121.0 43.9 28.5 63.3 54.0 182.0 38.5 9.5 10.1 234.7 82.0 272.6 243.7 14.0 11.9 22.1 52.2 42.4 39.3 253.3 13.3 26.0 191.5 3.7 131.6 28.9 18.8 29.6 128.8 88.9 11.5 197.2 73.6 22.8 19.5 63.7 43.6 31.9 140.6 176.3 43.3 21.3 80.3 75.9 27.6 69.9 103.7 286.1 218.4 626.5 1078.4 372.8 270.3 194.7 361.3 117.3 278.9 365.2 84.3 133.6 50.4 269.2 341.9 204.7 82.8 144.5 188.0 233.5 140.2 188.9 108.7 419.1 198.8 284.5 697.4 302.1 377.6 122.3 155.3 145.4 54.8 14.8 89.1 295.1 172.2 551.5 244.9 113.6 30.7 227.0 451.3 106.6 8.8 66.8 81.2 114.9 80.6 185.4 27.9 152.7 149.3 23.5 190.5 156.8 364.6 61.9 81.0 122.9 56.8 435.8 122.4 85.5 203.8 309.7 230.1 415.6 194.9 47.2 99.6 198.2 209.9 26.3 49.5 115.3 215.0 200.5 582.9 425.0 162.7 243.3 9.9 9.6 11.1 24.9 9.5 10.1 14.0 11.9 13.3 11.5 19.5 21.3 78.6 22.4 88.1 0.3 40.8 30.1 7.3 900.7 33.6 1.5 15.9 14.6 4.4 52.9 471.8 40.5 0.0 414.1 330.6 37.9 29.4 29.8 1.6 13.4 135.6 94.8 11.4 29.7 3.0 90.6 159.2 114.4 39.8 21.2 75.3 25.5 26.4 15.8 1100.6 0.0 8.2 19.4 158.7 344.7 200.7 7.9 198.5 391.7 48.0 61.8 185.4 0.5 299.7 13.6 0.4 44.8 72.3 25.6 78.5 8.5 20.2 166.4 93.7 0.8 59.2 4.4 150.8 3.0 11.1 43.3 27.1 227.3 170.6 286.7 44.9 16.1 CTSE ENSG00000196188 "Cathepsin E" P14091 1 206008535-206023909 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 1168.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 105.8;Exocrine glandular cells: 262.8;Gastric mucus-secreting cells: 553.5;Pancreatic endocrine cells: 260.0;Paneth cells: 208.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 297.4;stomach cancer: 200.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 46 "OE19: 1799.1" "Not detected" "Not detected" "HPA012674, HPA012940, CAB032687" Enhanced Approved Vesicles "Intracellular and membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB032687: AB_637901, HPA012674: , HPA012940: AB_2668773" "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-2)" "unprognostic (2.72e-2)" "unprognostic (1.35e-2)" "unprognostic (2.52e-3)" "unprognostic (1.45e-1)" "unprognostic (3.29e-2)" "unprognostic (2.87e-2)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "unprognostic (6.37e-3)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (2.61e-2)" "prognostic favorable (5.26e-5)" 0.3 0.0 0.1 9.5 0.1 30.0 0.0 0.5 0.3 0.0 0.1 15.3 229.8 0.3 1.7 0.8 1.1 15.0 0.3 0.1 0.1 0.2 0.2 49.7 0.5 0.3 0.1 0.1 3.7 0.0 1.1 1.3 0.3 0.2 25.7 0.1 0.0 1.6 0.0 0.1 55.5 0.3 0.1 0.6 1168.3 0.1 0.3 0.5 8.9 0.0 10.7 5.8 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.0 0.0 0.8 0.8 0.0 3.8 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.2 2.4 0.0 1.0 3.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.8 1.5 0.7 1799.1 0.1 0.4 0.0 0.8 0.7 39.4 0.2 0.5 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.2 0.5 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.6 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.5 0.3 0.1 0.1 0.3 0.1 0.3 0.1 0.3 0.5 0.0 105.8 27.9 0.0 0.6 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.5 10.0 42.3 0.0 0.0 0.0 0.0 34.1 0.0 52.0 0.0 0.3 0.0 0.3 2.4 60.6 0.0 262.8 0.1 14.7 553.5 0.6 0.0 0.0 0.0 0.2 0.2 0.0 0.0 21.1 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.6 0.0 0.0 0.0 0.1 260.0 208.9 0.0 0.7 0.1 4.0 0.1 7.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.1 10.4 0.4 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CTSS ENSG00000163131 "Cathepsin S" P25774 1 150730079-150765957 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 137.0;lymphoid tissue: 164.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 698.6;Kupffer cells: 2230.8;Macrophages: 1316.2;monocytes: 2312.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 2483.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 81.6;HMC-1: 187.5;U-698: 387.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000460, HPA002988" Supported Approved Vesicles "Intracellular and membrane" NA NA 23000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB000460: , HPA002988: AB_1078409" "unprognostic (7.81e-2)" "unprognostic (9.04e-2)" "unprognostic (3.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (6.00e-3)" "unprognostic (1.46e-1)" "unprognostic (3.89e-1)" "unprognostic (6.24e-2)" "unprognostic (7.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.13e-1)" "unprognostic (2.47e-3)" 40.0 16.7 4.0 87.8 4.5 137.0 20.3 4.8 7.1 9.4 8.0 83.6 60.2 7.8 5.7 16.5 17.8 29.1 10.6 3.4 5.5 9.3 40.4 88.4 71.7 11.8 8.0 4.9 11.3 2.3 4.7 23.6 11.2 9.1 59.4 3.4 23.9 7.3 4.1 7.1 64.6 16.3 7.7 164.8 42.6 3.8 10.4 20.1 11.5 9.0 38.5 42.9 10.0 16.1 3.7 10.9 0.2 0.3 1.2 1.4 0.7 0.4 8.6 0.9 1.3 1.2 81.6 44.3 5.7 1.2 15.3 2.1 0.2 0.7 0.5 26.9 0.2 29.0 1.1 0.8 0.2 33.6 187.5 2.6 0.1 6.6 1.5 0.5 6.3 0.6 3.4 45.0 2.4 0.3 0.4 22.5 0.2 0.1 0.3 14.9 4.6 49.8 10.7 8.7 0.3 0.4 1.1 2.3 0.8 0.3 0.4 49.8 9.1 6.2 1.3 0.8 1.2 27.8 2.2 387.3 28.5 35.2 2.3 20.9 2483.4 218.0 41.3 1735.3 51.1 139.5 46.6 50.9 571.0 138.8 45.0 40.8 1022.2 41.8 1655.1 106.8 77.4 2577.6 4.0 4.5 4.8 7.1 3.4 5.5 11.8 8.0 11.2 7.7 10.4 16.1 37.6 109.0 158.7 1.6 255.3 17.0 31.3 72.0 4.6 2.3 21.0 8.9 5.3 74.4 143.4 42.3 12.5 3.7 198.0 549.2 0.0 183.6 6.6 126.9 8.6 44.1 42.4 22.5 10.3 177.0 5.7 34.4 71.9 39.0 106.8 9.5 60.3 30.6 698.6 0.0 9.5 205.7 73.2 2230.8 316.4 3.0 5.3 1316.2 56.9 27.2 2312.9 0.5 137.0 0.5 0.9 200.9 466.5 2.2 121.4 20.6 210.8 4.7 488.9 4.9 19.7 5.6 13.3 0.2 0.5 12.4 15.5 6.2 108.9 66.0 237.8 113.3 CTSZ CTSX ENSG00000101160 "Cathepsin Z" Q9UBR2 20 58985686-59008238 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1078.9;Langerhans cells: 983.5;Macrophages: 652.3;monocytes: 723.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 542.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025114, HPA049876, HPA053504" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "CAB025114: , HPA049876: AB_2680927, HPA053504: AB_2682172" "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.07e-2)" "unprognostic (1.11e-3)" "unprognostic (8.25e-3)" "unprognostic (1.15e-1)" "unprognostic (4.12e-2)" "unprognostic (6.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (1.96e-1)" "unprognostic (6.92e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" 178.1 117.8 18.9 208.8 21.8 99.8 137.0 20.5 32.0 92.1 59.6 173.8 215.4 87.3 13.4 53.1 88.9 89.4 152.6 15.3 33.9 125.6 356.4 233.3 271.5 31.6 23.5 71.0 89.4 91.8 112.5 118.7 27.9 87.8 77.1 4.1 181.0 66.3 58.7 58.5 226.0 97.9 26.2 234.4 88.2 24.6 47.2 57.1 122.3 54.6 91.3 146.3 69.0 45.4 205.4 139.8 1.1 1.1 114.2 124.2 106.5 291.0 225.4 187.4 152.3 231.6 324.6 96.5 213.9 542.1 0.5 160.1 51.4 257.5 30.2 362.1 13.6 80.3 169.0 0.8 137.3 9.0 331.0 130.9 127.8 83.1 62.4 34.8 281.3 1.1 74.0 48.7 90.0 1.1 1.3 70.6 11.5 43.5 158.2 2.9 0.4 135.7 86.3 25.5 2.7 1.7 222.4 258.4 0.8 19.5 131.9 148.4 420.5 1.4 161.8 209.0 2.0 253.7 172.0 18.2 2.8 207.9 0.4 1.2 1.5 1.6 0.6 1.4 0.4 1.1 0.6 0.4 1.1 1.4 0.7 0.8 1.6 0.5 2.9 1.8 0.3 0.7 18.9 21.8 20.5 32.0 15.3 33.9 31.6 23.5 27.9 26.2 47.2 45.4 132.1 16.0 5.3 5.9 119.8 50.3 64.5 33.8 24.5 6.7 67.4 99.6 21.7 62.9 14.1 71.7 0.0 38.2 104.8 303.6 23.5 176.0 3.5 52.9 47.7 82.2 27.1 63.3 5.3 42.4 104.8 71.5 19.4 71.3 10.8 68.4 62.8 363.0 1078.9 11.8 3.0 56.6 26.4 334.0 983.5 6.0 13.1 652.3 101.4 23.4 723.6 58.6 21.6 2.5 2.5 82.6 217.5 13.9 96.3 50.6 339.8 90.0 18.8 5.0 46.0 67.5 74.5 3.7 4.8 14.5 41.5 41.3 33.4 3.3 99.7 52.7 CXCL5 "ENA-78, SCYB5" ENSG00000163735 "C-X-C motif chemokine ligand 5" P42830 4 73995642-73998677 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 35.9;salivary gland: 50.2" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 64.6;Ductal cells: 94.0;Macrophages: 222.6;Pancreatic endocrine cells: 245.4" "Group enriched" "Detected in many" 4 "pancreatic cancer: 56.2;stomach cancer: 74.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 191.9;EFO-21: 157.0;HSkMC: 111.4;hTEC/SVTERT24-B: 81.6;RPTEC TERT1: 603.6" HPA065474 Approved Approved Vesicles "Secreted to blood" NA NA 1110000 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA065474: AB_2685494" "unprognostic (5.56e-3)" "prognostic unfavorable (3.43e-4)" "unprognostic (1.80e-2)" "unprognostic (1.43e-2)" "unprognostic (2.04e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.06e-2)" "unprognostic (3.04e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (7.99e-2)" "prognostic unfavorable (2.45e-5)" "unprognostic (3.72e-1)" "unprognostic (3.07e-1)" "unprognostic (2.72e-2)" "unprognostic (9.30e-2)" 2.1 0.2 1.5 35.9 0.9 1.2 3.2 0.6 8.8 7.7 0.4 0.7 0.8 0.2 0.0 0.1 0.2 4.8 0.6 0.8 2.6 0.2 1.3 10.0 6.3 1.4 2.1 0.0 0.5 0.0 0.1 0.2 3.1 1.3 0.3 0.0 50.2 0.5 0.1 0.0 2.1 0.2 1.1 2.1 8.5 0.4 5.7 0.6 0.0 0.2 0.6 8.4 0.0 0.7 0.1 191.9 0.7 0.0 0.3 6.9 0.0 3.5 2.9 1.5 3.0 0.6 1.6 0.0 157.0 0.1 34.0 0.4 0.0 0.0 17.6 0.2 0.0 0.0 0.0 0.0 15.1 0.0 0.0 111.4 0.0 81.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 603.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.5 0.0 1.0 0.0 0.1 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 2.0 1.5 0.9 0.6 8.8 0.8 2.6 1.4 2.1 3.1 1.1 5.7 0.7 0.2 3.2 0.0 0.0 0.0 0.9 0.7 64.6 0.0 0.0 8.0 4.4 1.2 15.7 33.2 0.0 0.0 0.0 0.1 1.3 0.0 94.0 0.7 0.7 0.1 1.8 0.0 0.0 0.3 1.4 0.1 3.6 15.3 1.2 0.0 0.0 0.7 0.0 0.5 0.0 0.3 0.7 4.1 0.3 30.4 0.3 0.0 222.6 0.0 1.0 2.1 0.0 0.0 0.0 0.1 245.4 0.0 0.0 0.3 3.1 0.0 0.1 4.3 0.0 0.0 0.6 4.0 0.1 0.6 0.0 0.3 0.0 0.3 0.0 1.1 2.0 CYP17A1 "CPT7, CYP17, P450C17, S17AH" ENSG00000148795 "Cytochrome P450 family 17 subfamily A member 1" P05093 10 102830531-102837472 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Steroidogenesis "Lyase, Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 84 "adrenal gland: 8229.5" "Cell type enriched" "Detected in some" 17 "Theca cells: 1871.0" "Cancer enriched" "Detected in many" 5 "liver cancer: 22.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 3.0;SCLC-21H: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA048533 Enhanced Approved Vesicles "Intracellular and membrane" NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA048533: AB_2680432" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (3.01e-2)" "unprognostic (9.08e-2)" "unprognostic (1.91e-1)" "unprognostic (6.29e-2)" "unprognostic (2.92e-3)" "unprognostic (2.39e-4)" "unprognostic (8.26e-2)" "unprognostic (2.35e-1)" "unprognostic (5.92e-3)" "unprognostic (1.13e-1)" "prognostic favorable (5.43e-7)" "unprognostic (1.07e-1)" "unprognostic (5.56e-2)" "unprognostic (1.66e-2)" "unprognostic (2.94e-4)" 0.4 8229.5 0.0 2.1 0.0 0.0 0.4 0.1 0.1 1.1 0.0 0.5 0.0 0.8 0.1 0.9 1.0 0.4 1.0 0.0 0.0 52.9 6.7 1.4 0.0 0.0 0.1 16.6 1.7 10.5 0.7 0.0 0.0 0.7 0.0 0.2 3.4 0.0 1.0 0.7 0.6 0.0 0.0 0.9 1.3 98.3 0.0 0.0 2.9 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 2.2 0.1 0.4 0.1 0.0 0.5 0.0 0.1 0.7 0.0 0.0 1.8 0.0 0.4 0.1 0.1 21.5 0.0 41.6 0.1 0.0 0.7 0.0 2.7 0.1 0.2 0.0 1.3 0.0 0.1 0.0 0.1 0.4 6.1 0.1 1.7 0.1 0.0 0.0 0.6 0.7 10.6 1.8 0.9 0.0 0.0 0.1 0.2 3.1 0.5 0.1 0.7 0.0 0.0 0.0 0.3 0.0 104.3 0.0 1.2 0.0 1.2 0.6 0.3 0.1 0.0 0.0 0.3 0.4 1871.0 0.0 0.1 CYP27C1 FLJ16008 ENSG00000186684 "Cytochrome P450 family 27 subfamily C member 1" Q4G0S4 2 127183832-127220313 "Enzymes, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 4.1;skin 1: 5.1" "Cell type enhanced" "Detected in some" "Club cells: 5.4;Collecting duct cells: 3.7;Endometrial stromal cells: 5.8;Leydig cells: 7.5;Pancreatic endocrine cells: 7.6;Suprabasal keratinocytes: 7.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 7.6;HDLM-2: 11.8;hTERT-RPE1: 12.5;TIME: 11.6;U-138 MG: 10.9;U-251 MG: 7.9" "HPA062460, HPA068731" Enhanced Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA062460: AB_2732683, HPA068731: AB_2686023" "unprognostic (1.90e-1)" "unprognostic (4.07e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-2)" "unprognostic (3.03e-1)" "unprognostic (7.75e-3)" "unprognostic (3.48e-1)" "unprognostic (2.31e-3)" "unprognostic (4.38e-2)" "unprognostic (3.15e-1)" "unprognostic (1.81e-3)" "unprognostic (1.11e-1)" "unprognostic (6.29e-4)" "unprognostic (3.49e-4)" "unprognostic (1.83e-1)" "unprognostic (4.27e-2)" "unprognostic (8.64e-2)" 0.6 0.5 0.8 0.4 0.2 0.3 0.3 0.8 0.7 4.1 0.6 1.2 0.3 0.6 0.4 1.6 0.6 0.7 0.9 0.5 1.0 0.2 0.2 0.2 0.3 0.6 2.4 0.2 0.2 0.0 0.1 0.1 0.4 0.9 0.3 0.1 0.3 0.7 0.4 5.1 0.6 0.2 0.3 0.2 0.3 0.3 2.7 0.0 0.1 0.1 0.8 1.8 2.5 0.8 1.3 3.4 1.9 0.1 0.1 0.0 0.1 0.4 3.2 1.8 0.8 0.1 2.8 0.1 0.1 2.0 1.3 7.6 2.7 1.4 0.6 11.8 1.4 0.0 2.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 1.1 12.5 0.4 0.3 0.0 0.2 2.1 0.2 0.3 0.1 4.0 0.0 1.0 0.1 0.2 0.0 5.9 1.0 0.1 0.7 4.9 0.0 0.0 1.5 0.1 0.2 11.6 10.9 2.0 5.3 7.9 0.1 0.1 0.0 0.1 0.1 0.9 0.5 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.0 0.8 0.2 0.8 0.7 0.5 1.0 0.6 2.4 0.4 0.3 2.7 0.8 0.2 0.0 0.6 0.0 0.2 1.8 1.2 2.1 0.0 0.0 1.5 0.3 0.5 0.0 5.4 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 5.8 0.5 0.0 0.0 0.6 0.2 0.0 2.4 0.0 0.5 0.0 0.2 0.4 0.1 0.0 0.0 0.7 0.0 2.0 0.0 1.9 0.1 7.5 0.2 0.0 0.0 0.1 0.0 0.0 0.5 0.2 7.6 0.0 0.4 0.0 1.6 0.0 0.0 0.2 0.0 0.0 1.5 1.0 0.1 0.7 0.0 7.2 0.0 0.2 0.0 0.0 2.9 CYP2C19 "CPCJ, CYP2C, P450IIC19" ENSG00000165841 "Cytochrome P450 family 2 subfamily C member 19" P33261 10 94762681-94855547 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 190.2" "Group enriched" "Detected in some" 11 "Gastric mucus-secreting cells: 3.1;Hepatocytes: 9.5;Proximal enterocytes: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015066, HPA074424" Supported Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA015066: AB_1847433, HPA074424: " "unprognostic (3.15e-2)" "unprognostic (2.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.2 0.2 0.1 0.2 32.4 0.0 0.1 1.6 0.0 1.7 0.0 0.1 0.0 0.0 190.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.6 13.9 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 3.1 0.0 0.0 0.0 0.4 9.5 0.0 0.0 0.6 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 CYP4B1 ENSG00000142973 "Cytochrome P450 family 4 subfamily B member 1" P13584 1 46757838-46819413 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 242.2" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 1227.5;Club cells: 405.1;Respiratory ciliated cells: 763.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 56.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "RT4: 286.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA004331 Approved Supported Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA004331: AB_1078616" "unprognostic (2.29e-2)" "prognostic favorable (5.99e-4)" "unprognostic (7.01e-2)" "unprognostic (1.11e-1)" "unprognostic (2.28e-1)" "unprognostic (8.31e-2)" "unprognostic (1.16e-2)" "unprognostic (1.98e-2)" "unprognostic (2.65e-1)" "unprognostic (2.59e-1)" "unprognostic (6.12e-2)" "unprognostic (5.46e-2)" "unprognostic (7.33e-2)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.22e-3)" "unprognostic (6.69e-3)" 81.8 4.9 0.3 0.0 0.3 0.0 62.0 0.2 0.6 13.4 1.2 14.6 1.3 9.5 1.7 44.0 48.0 0.5 40.2 0.2 0.3 2.4 0.1 242.2 0.5 0.3 0.3 1.7 3.4 0.7 9.3 1.2 0.3 22.7 0.7 0.0 16.6 15.8 24.0 42.7 15.2 0.1 0.3 0.4 11.5 0.5 0.4 3.1 22.3 24.6 15.2 81.7 30.5 0.3 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 35.6 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 286.7 0.1 0.0 0.0 11.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.6 0.2 0.3 0.3 0.3 0.3 0.3 0.4 0.3 60.8 1227.5 89.3 0.0 0.0 0.5 139.6 111.5 36.5 0.0 2.0 1.5 6.4 1.5 405.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.7 93.8 12.5 23.5 0.0 0.0 0.1 0.0 0.2 47.9 1.1 8.5 6.3 0.0 1.4 0.0 0.6 0.0 0.1 0.0 48.8 0.0 0.3 0.9 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 6.9 0.0 1.1 763.9 0.0 0.0 3.0 23.3 0.1 0.1 71.4 4.1 0.8 1.8 0.0 0.0 163.0 DAB1 ENSG00000173406 "DAB adaptor protein 1" O75553 1 56994778-58546734 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.8;intestine: 22.3;seminal vesicle: 10.0" "Group enriched" "Detected in some" 8 "Excitatory neurons: 460.3;Inhibitory neurons: 1170.3;Oligodendrocyte precursor cells: 814.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 2.1" "Lineage enhanced" "Detected in single" "T-cells: 2.1" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 54.0;HeLa: 18.6;NTERA-2: 23.4;RT4: 32.0;WM-115: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032329, HPA052033, HPA067495" Enhanced Enhanced Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "CAB032329: AB_638973, HPA052033: AB_2681703, HPA067495: AB_2685852" "unprognostic (7.88e-2)" "unprognostic (1.02e-1)" "unprognostic (8.54e-2)" "unprognostic (2.09e-4)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (7.30e-4)" "unprognostic (3.90e-1)" "unprognostic (3.07e-2)" "unprognostic (1.47e-2)" "unprognostic (2.06e-3)" "unprognostic (1.27e-1)" "unprognostic (2.00e-3)" "unprognostic (1.78e-1)" "unprognostic (2.01e-1)" "unprognostic (1.44e-2)" "unprognostic (5.67e-2)" 2.0 1.7 4.3 0.4 5.3 0.0 0.3 16.8 8.8 1.6 0.0 0.8 15.8 0.5 0.4 0.6 1.6 0.7 1.8 10.6 5.4 0.3 7.7 0.4 0.2 2.1 3.9 1.2 0.4 0.0 0.2 0.0 2.0 3.9 0.3 5.4 0.9 10.0 0.1 0.1 22.3 0.3 2.3 0.2 1.0 0.4 5.1 0.1 0.3 0.1 0.1 1.2 0.9 1.9 0.0 0.0 10.6 0.0 0.1 0.2 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 54.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.8 0.0 0.0 0.0 0.0 2.0 0.1 23.4 0.0 0.0 6.0 0.0 0.2 0.0 32.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.6 0.1 0.0 2.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 4.3 5.3 16.8 8.8 10.6 5.4 2.1 3.9 2.0 2.3 5.1 1.9 0.7 0.0 0.0 30.0 0.1 0.0 0.1 0.1 0.0 23.7 0.1 0.3 3.2 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 8.6 8.2 0.6 0.3 0.0 0.0 460.3 0.0 0.0 0.4 4.6 12.8 0.0 0.0 0.7 5.1 0.1 21.9 1170.3 1.9 6.1 0.3 0.0 4.7 3.4 0.1 0.0 22.5 0.0 1.0 1.0 814.8 26.5 0.0 0.0 2.6 0.0 0.1 101.1 0.2 0.0 0.8 0.0 0.1 0.9 0.2 0.5 0.0 0.0 0.7 0.6 0.0 2.1 0.0 DENND6A "AFI1A, FAM116A, FLJ34969" ENSG00000174839 "DENN domain containing 6A" Q8IWF6 3 57625454-57693077 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 66.9;Inhibitory neurons: 65.4;Oligodendrocytes: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 18.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 18.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062618, HPA069725, HPA071711" Approved Supported Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA062618: AB_2684809, HPA069725: AB_2686184, HPA071711: AB_2686435" "unprognostic (6.20e-2)" "unprognostic (3.86e-2)" "prognostic favorable (9.21e-4)" "unprognostic (1.76e-1)" "unprognostic (7.75e-2)" "unprognostic (3.17e-1)" "prognostic unfavorable (6.36e-4)" "unprognostic (7.16e-2)" "unprognostic (1.17e-2)" "unprognostic (2.28e-3)" "unprognostic (5.97e-3)" "unprognostic (1.12e-1)" "prognostic favorable (7.77e-6)" "unprognostic (3.06e-1)" "unprognostic (1.63e-1)" "unprognostic (3.61e-3)" "unprognostic (2.94e-1)" 11.6 7.3 3.4 8.8 4.6 12.6 12.9 12.9 7.1 11.8 3.8 10.7 7.1 12.7 9.9 11.4 10.3 8.3 8.0 3.0 5.5 8.9 7.7 10.5 12.6 4.2 4.8 20.9 5.3 11.4 6.6 11.8 5.3 9.9 9.2 10.0 8.4 11.7 7.1 8.6 9.2 11.3 4.7 12.9 9.7 8.0 4.7 11.8 14.0 9.8 10.5 10.7 10.5 8.4 16.8 13.5 18.0 11.0 9.4 10.6 10.2 8.6 11.0 10.5 8.2 8.7 18.4 19.9 3.6 8.9 9.2 8.8 14.4 18.2 8.9 5.1 12.9 15.7 15.1 6.7 9.0 12.1 8.9 11.3 13.0 7.2 18.7 10.6 15.2 21.1 10.8 21.1 7.6 7.3 26.2 14.9 10.2 10.6 9.3 10.9 10.7 14.8 12.8 28.1 6.1 22.0 17.1 13.9 12.5 7.7 9.1 14.7 16.7 12.7 6.8 13.6 22.8 15.7 22.2 20.7 14.8 19.9 18.9 18.7 1.0 1.4 2.4 1.1 2.9 0.8 2.3 2.4 1.3 1.2 3.4 2.6 1.5 1.9 1.4 1.0 1.3 1.0 3.4 4.6 12.9 7.1 3.0 5.5 4.2 4.8 5.3 4.7 4.7 8.4 28.8 19.2 8.2 31.3 14.5 12.9 11.8 10.6 12.0 16.2 9.9 9.1 20.8 11.5 10.0 5.5 8.4 6.4 21.4 5.7 3.9 8.1 22.2 10.1 25.6 16.0 3.0 16.2 66.9 10.9 4.4 15.7 10.2 17.1 2.5 24.1 20.7 11.1 11.1 10.1 65.4 5.5 12.2 34.3 9.9 11.3 11.8 16.8 3.6 47.8 16.8 10.2 20.6 42.3 74.3 18.9 3.5 14.3 9.5 8.4 6.5 8.9 8.0 14.5 6.6 19.2 18.3 13.3 5.0 14.1 10.7 2.3 19.6 16.7 6.1 13.0 DERL3 "C22orf14, derlin-3, FLJ43842, IZP6, MGC71803" ENSG00000099958 "Derlin 3" Q96Q80 22 23834503-23839128 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.6;pancreas: 60.8;salivary gland: 51.1" "Cell type enriched" "Detected in many" 6 "Plasma cells: 1428.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "plasmacytoid DC: 187.4" "Lineage enriched" "Detected in many" 14 "dendritic cells: 187.4" "Cell line enhanced" "Detected in some" "Karpas-707: 26.9;RPMI-8226: 23.6;U-266/70: 48.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB037234, HPA049306" Approved Uncertain Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB037234: AB_1840802, HPA049306: " "unprognostic (2.01e-3)" "prognostic favorable (8.70e-5)" "unprognostic (9.72e-3)" "unprognostic (7.47e-2)" "unprognostic (9.77e-3)" "prognostic favorable (8.01e-4)" "unprognostic (2.23e-2)" "unprognostic (1.40e-1)" "unprognostic (1.36e-1)" "unprognostic (8.66e-3)" "unprognostic (4.74e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.76e-13)" "unprognostic (1.53e-2)" "unprognostic (4.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.95e-1)" 2.6 3.2 1.4 4.3 1.4 1.8 5.4 1.3 2.2 6.1 1.9 30.6 10.0 3.7 0.2 4.3 7.1 2.3 7.7 1.3 1.6 5.7 9.1 9.2 9.2 1.8 2.2 2.0 60.8 0.8 8.1 0.8 1.7 3.3 10.9 0.2 51.1 3.8 2.7 0.8 33.7 0.7 1.7 61.6 29.4 24.8 1.7 1.6 14.6 0.2 17.6 3.6 2.3 1.5 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 4.5 4.8 0.9 0.0 1.4 0.0 1.1 1.3 0.0 0.5 4.8 0.4 4.6 0.0 0.7 3.2 0.6 0.0 0.2 0.5 0.0 0.1 0.1 0.5 0.8 26.9 0.0 0.0 1.3 2.2 1.0 2.3 0.3 4.2 0.0 23.6 0.9 0.3 0.6 0.1 0.1 0.0 0.2 0.7 0.0 1.5 0.0 0.0 0.0 0.4 0.1 48.5 6.3 8.3 0.8 6.2 0.1 0.0 0.0 0.0 0.2 0.1 0.2 13.8 0.0 0.0 0.0 12.4 0.1 0.0 0.1 0.0 0.0 187.4 0.0 1.3 1.4 1.4 1.3 2.2 1.3 1.6 1.8 2.2 1.7 1.7 1.7 1.5 0.5 0.0 1.1 0.3 183.8 1.8 1.5 3.7 0.6 1.1 19.3 1.8 3.5 1.5 4.1 0.0 2.1 0.8 141.7 2.7 0.0 0.5 113.2 33.8 0.9 1.1 1.8 8.2 0.3 5.8 6.2 2.2 7.7 1.7 2.5 15.7 4.6 7.8 3.4 0.0 1.7 7.9 4.1 2.2 2.1 158.2 2.5 5.4 224.1 1.9 0.5 0.8 0.0 1.0 0.5 1.1 0.5 4.1 1428.8 2.5 0.8 0.5 30.3 0.6 0.0 0.8 2.6 67.0 32.9 1.3 2.0 15.5 17.9 2.1 10.7 2.0 DESI2 "C1orf121, CGI-146, DESI-2, FAM152A, FLJ21998, PNAS-4, PPPDE1" ENSG00000121644 "Desumoylating isopeptidase 2" Q9BSY9 1 244653103-244709033 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 171.8;Spermatocytes: 192.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049950 Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA049950: AB_2680969" "unprognostic (1.13e-1)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (5.40e-2)" "unprognostic (1.95e-2)" "unprognostic (7.62e-2)" "unprognostic (1.38e-3)" "unprognostic (1.51e-1)" "unprognostic (4.47e-3)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.25e-5)" "unprognostic (4.52e-2)" "unprognostic (8.27e-2)" "unprognostic (2.27e-2)" "unprognostic (9.49e-2)" 17.1 13.6 7.7 13.6 10.7 17.1 14.0 13.0 8.4 18.4 13.1 16.4 16.0 22.7 13.6 16.2 13.3 17.8 16.4 7.4 7.9 11.8 12.8 23.2 17.9 7.7 8.0 13.6 9.3 13.9 7.1 18.6 7.4 14.4 18.2 16.2 11.1 15.6 24.1 15.2 13.3 22.3 8.1 11.7 15.6 54.8 8.3 19.7 23.3 23.6 19.1 18.4 12.0 8.1 68.1 24.3 47.0 40.8 52.8 54.8 61.7 40.8 65.9 36.9 33.9 43.8 31.0 121.8 53.8 47.7 21.5 29.5 58.1 43.1 50.5 43.1 53.6 31.0 17.5 33.0 46.2 52.8 36.1 38.4 57.3 49.3 61.6 35.6 52.8 52.8 48.4 63.7 56.2 11.7 49.6 28.0 109.0 62.7 67.7 36.9 71.9 46.0 28.4 27.6 42.5 57.2 55.4 26.4 47.7 37.7 27.6 39.0 59.7 41.7 45.4 57.4 68.5 69.4 94.1 69.8 33.8 55.7 78.0 2.5 1.7 5.6 2.1 2.1 2.1 5.2 2.2 3.0 2.7 2.7 2.9 2.8 1.4 2.2 2.3 2.4 3.2 0.7 7.7 10.7 13.0 8.4 7.4 7.9 7.7 8.0 7.4 8.1 8.3 8.1 32.7 86.6 60.4 17.9 31.0 55.3 41.3 23.0 38.7 43.2 21.5 26.3 22.1 27.1 25.5 18.4 20.9 29.8 36.1 28.1 21.5 19.8 171.8 32.0 39.6 36.2 15.6 21.7 18.4 33.4 40.0 44.2 28.5 25.0 7.0 28.7 25.7 21.5 23.8 40.4 23.1 19.0 26.4 23.3 27.1 101.5 34.8 27.2 16.0 18.7 25.5 23.8 28.8 35.7 26.9 34.3 28.6 51.9 34.5 69.5 17.0 16.5 17.6 25.1 39.5 41.7 50.2 192.7 105.4 42.4 41.3 43.2 31.2 38.4 25.4 55.5 DHRS13 "MGC23280, SDR7C5" ENSG00000167536 "Dehydrogenase/reductase 13" Q6UX07 17 28897781-28903079 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 41.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 55.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 55.3" "Cell line enhanced" "Detected in all" "SK-BR-3: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA022991 Uncertain Approved Vesicles "Secreted - unknown location" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "HPA022991: AB_1853865" "unprognostic (8.87e-2)" "unprognostic (1.64e-1)" "unprognostic (1.91e-1)" "unprognostic (2.35e-1)" "unprognostic (1.21e-2)" "unprognostic (6.37e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (2.38e-1)" "unprognostic (4.74e-2)" "unprognostic (5.65e-2)" "unprognostic (1.20e-2)" "unprognostic (7.57e-2)" "unprognostic (1.73e-2)" "unprognostic (3.72e-2)" "unprognostic (2.63e-1)" "unprognostic (7.22e-3)" "unprognostic (2.55e-1)" 3.1 7.0 9.9 5.7 8.6 41.8 5.4 17.1 9.6 6.4 11.8 4.8 4.4 3.0 6.6 8.8 4.1 2.9 2.8 8.6 15.3 12.2 23.6 4.7 6.6 13.0 14.9 3.5 6.6 7.9 6.3 4.5 14.0 19.4 3.6 8.3 12.7 10.6 1.3 7.4 4.0 2.2 10.1 10.2 5.9 3.0 13.0 4.6 4.7 2.3 6.9 9.5 6.3 9.5 12.1 7.6 17.4 22.2 2.6 3.8 16.8 6.4 8.3 11.6 17.7 23.5 7.1 32.8 10.7 1.4 13.4 10.5 24.8 7.1 4.9 33.5 23.9 18.4 13.9 13.0 6.5 9.5 2.1 2.8 6.3 7.3 7.7 8.1 3.6 22.7 42.3 11.0 2.3 21.7 20.9 15.9 10.7 31.4 1.0 32.8 16.4 25.5 21.8 20.2 24.8 20.8 10.1 69.5 13.9 9.1 46.4 15.2 1.2 3.7 11.1 9.0 8.9 25.5 25.7 20.7 11.0 11.9 9.4 0.9 4.4 3.1 8.5 6.9 10.4 7.1 10.8 10.7 5.9 8.6 10.9 8.1 55.3 9.4 6.8 3.2 11.4 5.8 9.9 8.6 17.1 9.6 8.6 15.3 13.0 14.9 14.0 10.1 13.0 9.5 2.4 3.2 4.2 2.3 6.7 1.5 10.2 12.3 12.0 6.1 7.1 5.7 0.4 8.6 5.4 7.3 2.1 27.7 4.4 4.3 9.8 10.6 11.9 3.4 1.1 4.5 3.0 106.1 0.7 2.7 22.2 2.1 7.7 6.3 1.3 1.2 6.4 5.5 6.2 5.0 4.4 4.2 2.0 0.8 3.0 5.2 1.2 2.1 5.4 1.0 15.5 8.2 10.3 3.0 1.0 2.5 2.4 0.4 12.8 11.5 2.8 3.2 2.2 5.0 6.6 0.9 1.1 6.1 22.5 9.4 1.7 13.5 7.0 0.5 6.4 5.8 DIO3 TXDI3 ENSG00000197406 "Iodothyronine deiodinase 3" P55073 14 101561351-101563452 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 25.0;placenta: 17.8" "Cell type enhanced" "Detected in some" "Endothelial cells: 7.8;Fibroblasts: 27.9;Leydig cells: 10.8;Muller glia cells: 8.1;Peritubular cells: 7.5;Skeletal myocytes: 16.3;Syncytiotrophoblasts: 28.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "AF22: 54.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "amygdala: 4.4;hippocampal formation: 5.6" HPA073684 Supported Vesicles NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA073684: " "unprognostic (4.52e-3)" "unprognostic (1.80e-1)" "unprognostic (3.04e-3)" "unprognostic (3.48e-1)" "unprognostic (5.16e-2)" "unprognostic (1.50e-1)" "unprognostic (4.24e-2)" "unprognostic (8.11e-2)" "unprognostic (2.58e-1)" "unprognostic (6.24e-2)" "unprognostic (2.34e-1)" "unprognostic (2.52e-1)" "unprognostic (7.46e-5)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (1.11e-4)" "unprognostic (9.80e-3)" 5.0 0.4 0.5 1.8 1.2 0.0 3.2 0.2 1.2 25.0 0.2 1.7 0.0 6.5 0.6 1.8 6.7 3.0 0.6 0.6 0.2 0.3 3.9 2.6 1.3 1.3 0.3 13.6 1.5 0.0 0.7 17.8 0.3 3.2 0.4 0.7 1.7 2.2 1.6 3.5 1.7 0.9 0.4 0.6 1.6 1.3 3.3 0.2 4.1 3.0 0.1 5.2 15.4 0.4 0.0 0.2 54.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.1 0.0 0.0 1.0 1.3 0.8 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.2 0.2 1.2 0.6 0.2 1.3 0.3 0.3 0.4 3.3 0.4 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.6 0.4 0.0 0.0 0.0 0.0 1.9 0.0 5.9 0.0 0.6 0.3 0.4 4.9 7.8 0.0 0.0 0.1 0.0 2.5 27.9 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.5 0.0 0.0 0.7 0.6 10.8 0.1 0.0 0.0 0.6 8.1 0.0 0.0 0.0 0.9 1.1 7.5 0.0 0.8 0.0 0.0 0.0 0.2 0.0 16.3 0.7 0.1 0.2 0.2 0.1 28.3 0.2 0.1 0.3 0.4 DKKL1 "CT34, SGY-1" ENSG00000104901 "Dickkopf like acrosomal protein 1" Q9UK85 19 49361783-49375116 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 277 "testis: 344.8" "Group enriched" "Detected in some" 4 "Early spermatids: 2188.8;Late spermatids: 2340.4" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "memory B-cell: 1.7" "Lineage enriched" "Detected in single" 17 "B-cells: 1.7" "Cell line enhanced" "Detected in some" "AF22: 5.1;AN3-CA: 9.8;HeLa: 2.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025410, HPA047194" Enhanced Approved Vesicles "Secreted in male reproductive system" NA NA "Cluster 37: B-cells - Transcription" "Cluster 36: Testis - Spermatogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB025410: , HPA047194: AB_2679979" "unprognostic (1.64e-1)" "unprognostic (5.30e-1)" "unprognostic (5.39e-4)" "unprognostic (1.85e-4)" "unprognostic (3.79e-2)" "unprognostic (4.30e-2)" "unprognostic (5.52e-4)" "unprognostic (1.00e-1)" "unprognostic (6.76e-2)" "unprognostic (4.08e-1)" "unprognostic (1.90e-1)" "unprognostic (5.65e-2)" "unprognostic (2.56e-3)" "unprognostic (1.36e-1)" "unprognostic (1.13e-1)" "unprognostic (1.18e-1)" "unprognostic (5.57e-2)" 0.7 0.5 0.3 0.5 0.3 0.0 0.5 0.2 0.5 0.7 0.4 0.5 0.3 1.1 0.3 0.2 1.2 0.7 0.4 0.2 0.1 0.6 0.3 0.3 0.5 0.4 0.3 0.8 1.0 0.1 0.1 0.3 0.2 0.6 0.1 0.3 0.9 0.6 0.2 0.2 0.3 0.4 0.3 0.4 0.3 344.8 0.2 0.0 0.2 0.4 0.2 0.4 0.4 0.3 0.0 1.2 5.1 9.8 0.0 0.3 0.4 0.9 0.0 0.1 0.3 0.0 0.5 0.0 0.7 0.1 0.4 0.0 0.1 0.0 0.0 0.0 1.7 0.0 2.9 0.2 0.0 0.0 0.9 0.7 0.3 0.2 0.3 0.9 0.8 0.0 1.2 0.3 0.1 0.4 0.0 0.0 2.0 0.5 1.1 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.9 0.0 0.5 1.0 1.0 2.0 1.2 1.0 0.6 0.6 0.0 0.4 0.6 0.2 0.0 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.5 0.2 0.1 0.4 0.3 0.2 0.3 0.2 0.3 1.3 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.6 0.6 1.2 2.2 0.4 0.0 0.1 0.0 2.1 0.0 0.0 0.1 0.0 0.4 2188.8 0.5 1.0 1.9 0.0 0.0 0.2 0.5 0.2 0.7 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 2340.4 16.8 1.4 1.8 0.0 0.0 2.1 0.0 0.0 0.0 0.3 0.0 12.0 0.0 0.2 0.0 0.0 0.0 0.4 6.6 0.7 0.9 491.0 15.2 0.2 0.0 0.0 0.1 0.5 0.2 0.2 DMRTA1 ENSG00000176399 "DMRT like family A1" Q5VZB9 9 22446824-22455740 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 8.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 19.4;Distal tubular cells: 15.6;Glandular and luminal cells: 14.5;Hepatocytes: 30.8;Proximal tubular cells: 29.2;Squamous epithelial cells: 26.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 6.3;hTERT-RPE1: 7.4;LHCN-M2: 2.9;RPTEC TERT1: 3.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.2" "HPA044764, HPA062253" Uncertain Approved Vesicles NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA044764: AB_10959788, HPA062253: AB_2684726" "unprognostic (1.47e-1)" "unprognostic (2.48e-2)" "unprognostic (2.86e-1)" "unprognostic (7.74e-4)" "unprognostic (3.81e-2)" "unprognostic (2.67e-3)" "unprognostic (4.36e-2)" "unprognostic (2.36e-2)" "unprognostic (1.28e-1)" "unprognostic (9.64e-2)" "unprognostic (3.65e-3)" "unprognostic (2.92e-1)" "prognostic favorable (1.14e-6)" "unprognostic (8.58e-2)" "unprognostic (1.13e-1)" "unprognostic (1.61e-1)" "unprognostic (8.53e-3)" 1.8 0.0 0.4 0.2 0.4 0.0 0.4 0.3 0.3 1.6 2.4 0.4 0.6 0.3 1.2 1.7 0.3 0.9 0.3 0.6 0.3 3.4 8.4 0.9 0.4 0.4 1.6 0.2 1.4 2.2 0.7 0.0 0.4 1.4 0.3 0.1 3.5 0.4 0.7 0.2 0.5 0.1 0.4 0.2 2.0 0.1 0.7 0.5 1.8 1.1 0.8 0.4 0.1 0.4 0.2 0.3 0.0 0.0 0.2 0.1 0.1 0.0 6.3 0.2 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.2 1.2 1.7 0.2 0.0 0.4 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.1 7.4 0.4 0.0 0.0 2.3 2.9 0.6 0.0 0.0 1.2 0.3 2.1 0.0 0.1 0.9 3.0 0.0 0.1 0.0 0.8 0.5 1.4 1.4 0.0 0.0 2.1 0.0 2.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.3 0.6 0.3 0.4 1.6 0.4 0.4 0.7 0.4 0.1 0.0 2.7 2.0 0.1 0.0 4.8 7.2 19.4 0.5 1.9 1.0 1.9 5.7 5.6 5.5 0.0 0.0 0.0 1.1 15.6 6.9 0.1 10.7 1.4 0.3 2.4 0.0 0.0 6.7 0.0 0.8 10.2 14.5 0.0 0.6 0.0 30.8 0.3 0.0 0.0 0.7 8.2 0.3 0.3 0.1 0.3 0.4 0.0 1.0 0.0 5.4 0.0 0.0 0.0 7.8 0.2 0.0 0.1 6.3 4.1 29.2 5.9 0.1 0.0 2.9 0.6 0.2 1.2 26.5 0.4 0.1 0.3 0.0 1.9 8.2 DNAJC16 KIAA0962 ENSG00000116138 "DnaJ heat shock protein family (Hsp40) member C16" Q9Y2G8 1 15526813-15592379 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043643 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA043643: AB_10796794" "unprognostic (1.77e-1)" "unprognostic (4.95e-2)" "prognostic favorable (6.77e-4)" "unprognostic (4.52e-2)" "unprognostic (5.51e-2)" "unprognostic (2.05e-2)" "unprognostic (1.91e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (4.28e-2)" "unprognostic (2.35e-2)" "unprognostic (3.74e-2)" "prognostic favorable (7.24e-4)" "unprognostic (3.67e-2)" "unprognostic (3.74e-1)" "unprognostic (5.38e-2)" "unprognostic (4.70e-2)" 4.9 5.2 4.5 5.5 5.3 2.2 6.5 5.4 6.5 5.0 7.8 6.0 6.5 5.6 7.6 5.4 6.8 4.5 5.1 5.3 4.9 11.5 10.1 4.8 6.2 4.2 4.4 5.7 6.4 10.0 5.3 5.8 4.8 5.5 5.9 9.0 7.0 4.8 11.9 5.6 5.8 6.3 4.1 5.7 5.4 6.3 5.0 5.1 7.4 6.3 6.4 5.2 4.6 6.4 8.8 8.7 6.7 12.4 18.0 14.5 6.3 10.4 10.7 10.2 10.9 7.1 12.7 7.6 6.8 10.3 13.3 10.7 8.3 9.2 14.3 9.0 4.0 7.8 9.6 12.2 17.8 12.2 8.7 10.5 10.6 16.4 9.2 12.7 11.6 6.3 16.9 6.7 11.8 3.6 6.2 6.2 6.5 7.9 5.6 7.3 8.6 8.5 12.6 6.0 7.5 7.0 10.6 10.1 9.0 9.6 6.3 4.8 15.7 17.9 6.4 16.7 5.7 9.1 13.8 6.6 11.1 6.9 8.7 2.0 2.1 1.5 2.6 2.0 3.9 3.4 2.8 2.4 2.1 3.1 3.5 3.0 1.1 1.6 1.5 1.9 2.8 1.9 4.5 5.3 5.4 6.5 5.3 4.9 4.2 4.4 4.8 4.1 5.0 6.4 11.6 0.0 8.7 25.5 12.4 5.1 4.3 13.8 9.6 14.9 16.1 8.4 16.9 22.8 14.9 25.8 22.9 12.8 11.5 13.7 1.9 9.1 11.6 25.5 19.0 12.0 11.5 4.6 33.5 6.9 7.7 10.5 11.7 17.6 8.2 14.0 16.4 20.5 10.9 18.5 28.6 9.7 18.3 20.6 5.5 5.8 12.5 9.5 7.2 17.8 11.4 12.8 12.3 19.1 28.8 9.3 7.5 11.3 6.8 12.6 10.6 19.0 37.5 16.0 6.6 11.7 7.8 24.7 15.7 13.0 5.8 22.0 7.1 11.4 13.4 8.2 DNAJC22 "FLJ13236, wus" ENSG00000178401 "DnaJ heat shock protein family (Hsp40) member C22" Q8N4W6 12 49346888-49357546 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 24.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 47.1;Distal enterocytes: 36.8;Exocrine glandular cells: 42.9;Hepatocytes: 44.6;Intestinal goblet cells: 26.9;Pancreatic endocrine cells: 27.6;Paneth cells: 26.2;Proximal enterocytes: 59.6;Undifferentiated cells: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 10.5;CACO-2: 19.1;EFO-21: 17.2;MCF7: 18.8;OE19: 18.6" "Region enhanced" "Detected in single" "midbrain: 1.2" "Low region specificity" "Detected in all" HPA039953 Approved Vesicles NA NA "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA039953: AB_2676770" "unprognostic (5.23e-2)" "unprognostic (1.24e-1)" "unprognostic (9.01e-2)" "prognostic favorable (4.56e-5)" "unprognostic (4.77e-3)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (4.05e-2)" "prognostic unfavorable (7.54e-4)" "unprognostic (6.14e-2)" "unprognostic (1.23e-2)" "unprognostic (2.49e-1)" "unprognostic (1.49e-2)" "unprognostic (3.18e-2)" "unprognostic (9.35e-2)" "unprognostic (1.58e-1)" "unprognostic (3.83e-2)" 1.2 0.2 0.5 0.4 0.7 0.2 0.3 1.5 0.8 1.1 0.6 4.0 5.6 0.6 0.3 0.0 0.7 3.1 0.1 0.5 0.5 3.7 24.1 0.1 0.1 1.7 1.4 0.0 5.6 2.0 0.2 0.2 1.8 0.2 2.2 0.2 1.4 0.1 0.0 0.4 5.0 0.2 0.7 0.2 3.0 0.6 0.8 0.0 4.4 0.0 0.0 0.1 0.7 1.1 0.9 5.6 0.0 10.5 0.0 0.0 2.4 0.0 1.9 0.5 1.3 19.1 4.0 0.0 17.2 0.5 0.6 0.2 1.2 0.0 1.5 0.0 3.5 0.2 0.4 6.3 1.1 0.1 1.2 0.2 0.1 0.6 0.1 2.8 0.5 0.1 0.1 0.2 0.6 18.8 0.0 0.1 0.1 18.6 5.8 0.0 3.6 0.1 0.3 0.1 2.6 0.6 0.1 0.3 2.4 0.1 6.7 0.0 0.2 0.6 2.1 0.1 0.6 0.0 0.0 0.0 1.7 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.7 1.5 0.8 0.5 0.5 1.7 1.4 1.8 0.7 0.8 1.1 0.2 0.0 1.1 1.0 0.3 0.6 1.5 3.0 0.0 0.3 5.9 3.7 0.5 47.1 2.0 1.8 0.0 0.1 0.3 36.8 0.0 16.0 4.1 6.2 4.5 0.6 21.0 0.0 0.5 42.9 0.3 3.8 10.2 5.9 1.3 4.7 1.4 44.6 0.1 3.3 0.2 26.9 0.0 0.8 0.4 1.9 0.0 0.4 3.6 0.0 0.6 0.6 0.0 0.0 5.7 27.6 26.2 0.7 0.0 0.7 59.6 18.6 5.7 0.5 0.0 0.5 2.1 1.9 1.9 0.0 0.3 0.4 0.5 1.0 26.2 0.4 DNASE1 DNL1 ENSG00000213918 "Deoxyribonuclease 1" P24855 16 3611728-3680143 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Actin-binding, Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 34.5;kidney: 34.2" "Cell type enriched" "Detected in many" 11 "Proximal enterocytes: 715.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010703 Enhanced Supported Vesicles "Secreted in other tissues" NA NA 420000 "Cluster 49: Eosinophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA010703: AB_10600806" "unprognostic (5.18e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (2.38e-1)" "unprognostic (1.90e-2)" "unprognostic (3.73e-2)" "unprognostic (3.82e-1)" "unprognostic (3.20e-1)" "unprognostic (9.91e-2)" "unprognostic (1.69e-3)" "unprognostic (5.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.14e-4)" 4.6 5.0 5.1 6.6 5.6 4.3 4.6 13.4 6.4 9.8 6.9 6.1 29.7 5.2 5.0 7.1 6.8 2.7 5.5 5.8 4.9 34.2 5.9 4.9 10.0 6.0 5.2 7.5 23.6 2.7 16.3 4.2 6.6 11.6 5.0 4.4 4.9 2.5 3.7 7.8 34.5 2.7 3.2 9.2 11.2 9.2 5.8 9.4 7.4 1.3 8.7 6.0 8.5 9.7 2.9 6.5 11.4 5.9 3.3 2.8 5.2 4.7 0.8 3.7 5.3 8.0 6.9 12.3 3.6 0.7 7.8 4.8 4.2 1.3 3.9 5.5 6.4 4.4 11.3 5.4 1.7 2.9 9.6 2.3 4.8 5.0 1.2 5.8 2.5 10.3 11.2 5.0 3.2 12.3 6.3 13.6 6.9 8.7 3.6 14.9 5.3 5.7 3.1 2.5 8.1 7.6 3.5 10.5 1.9 5.7 10.4 7.7 3.4 6.8 5.0 4.3 2.5 4.8 7.5 21.4 1.7 5.7 6.6 2.7 1.1 3.2 1.5 0.7 1.0 1.4 1.2 1.3 0.6 2.1 1.3 1.8 5.0 1.0 0.7 1.1 1.4 0.5 5.1 5.6 13.4 6.4 5.8 4.9 6.0 5.2 6.6 3.2 5.8 9.7 4.9 9.6 10.3 27.1 9.1 2.7 8.6 3.1 10.8 27.3 5.5 4.8 6.0 4.3 9.7 16.5 22.9 8.6 9.3 11.8 56.7 5.3 19.3 9.8 10.0 7.7 14.3 7.6 20.5 11.0 4.1 7.4 13.3 8.4 2.5 23.3 7.5 1.8 3.9 25.2 22.0 38.6 20.3 5.0 4.2 52.4 8.4 4.4 1.8 15.9 13.2 8.6 30.9 22.1 20.6 5.3 61.4 7.9 7.2 12.4 715.5 2.4 9.1 17.9 0.0 13.6 6.3 28.5 24.5 5.8 3.8 6.2 12.2 10.4 33.4 6.3 DPT ENSG00000143196 Dermatopontin Q07507 1 168695468-168729206 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 424.7" "Group enriched" "Detected in many" 5 "Fibroblasts: 457.5;Leydig cells: 231.8;Peritubular cells: 123.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 143.3;fHDF/TERT166: 59.9" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 1.0" HPA065548 Approved Vesicles "Secreted to extracellular matrix" NA NA 610000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA065548: AB_2685511" "unprognostic (1.49e-1)" "unprognostic (7.62e-2)" "unprognostic (5.66e-2)" "unprognostic (4.39e-2)" "unprognostic (4.64e-2)" "unprognostic (3.78e-3)" "unprognostic (4.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (8.88e-2)" "unprognostic (2.16e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.12e-3)" "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (8.98e-3)" 334.6 39.6 0.4 28.6 0.5 0.0 251.3 0.5 1.0 177.6 0.5 424.7 18.8 63.2 60.8 86.0 129.1 78.0 241.4 0.5 0.4 13.2 29.0 48.6 58.6 0.5 0.4 30.3 84.8 4.9 2.1 37.5 0.6 55.2 58.2 0.0 72.0 52.7 37.1 39.2 94.2 138.5 0.5 0.9 108.5 15.4 0.5 48.0 75.0 209.3 70.1 103.3 166.9 0.7 0.0 0.0 0.0 0.0 143.3 0.6 0.2 0.1 6.7 7.2 7.4 0.0 0.0 0.0 0.0 59.9 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 4.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 7.6 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.5 1.0 0.5 0.4 0.5 0.4 0.6 0.5 0.5 0.7 18.7 3.2 1.7 0.3 0.3 31.9 0.1 0.0 1.8 0.0 2.2 2.3 7.4 0.0 0.6 0.0 0.0 0.6 0.4 0.1 0.0 0.1 1.2 0.3 10.7 6.9 0.0 0.0 4.8 0.2 0.8 457.5 3.1 0.2 0.0 0.0 8.9 0.0 0.6 0.0 3.4 0.0 0.0 0.0 45.6 4.4 231.8 4.0 39.2 1.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 123.8 0.5 0.5 0.0 0.1 0.0 0.0 0.0 24.4 18.5 0.5 0.3 3.1 32.0 0.4 5.0 2.2 0.0 0.6 DPY19L1 KIAA0877 ENSG00000173852 "Dpy-19 like C-mannosyltransferase 1" Q2PZI1 7 34928876-35038271 "Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 206.2;Excitatory neurons: 132.8;Late spermatids: 72.0;Oligodendrocytes: 95.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059139 Uncertain Approved Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA059139: AB_2683921" "unprognostic (4.66e-2)" "unprognostic (1.11e-3)" "unprognostic (8.53e-3)" "unprognostic (2.47e-3)" "unprognostic (2.50e-2)" "unprognostic (3.80e-3)" "unprognostic (2.02e-3)" "unprognostic (3.57e-2)" "unprognostic (1.14e-1)" "unprognostic (4.84e-2)" "prognostic unfavorable (2.99e-4)" "unprognostic (3.21e-1)" "unprognostic (1.88e-2)" "unprognostic (3.99e-1)" "unprognostic (2.69e-2)" "unprognostic (1.37e-1)" "unprognostic (4.12e-2)" 10.8 13.2 16.5 12.1 18.6 11.2 6.4 22.2 22.3 15.9 11.0 10.6 5.3 18.9 4.1 7.6 10.7 15.2 14.9 18.0 23.2 7.0 19.5 14.7 10.7 23.6 22.9 9.0 5.6 4.1 6.2 21.6 22.0 9.0 12.1 27.9 7.1 8.4 3.5 4.6 6.2 19.3 25.2 15.7 10.1 38.1 21.5 4.8 11.4 6.1 9.8 16.5 5.5 33.4 16.7 64.6 36.2 46.3 69.7 55.3 7.5 36.6 30.7 22.4 29.3 15.5 42.4 24.2 52.1 38.2 92.4 29.1 27.2 20.1 50.1 12.4 22.2 35.3 40.2 25.7 24.5 33.6 31.6 27.3 16.5 29.7 20.1 63.1 93.5 11.9 26.9 95.8 79.3 8.1 0.3 33.3 23.3 39.2 28.9 24.7 47.8 34.8 85.0 57.4 16.7 43.4 32.8 4.2 19.4 56.5 32.6 38.6 109.1 44.3 53.1 30.9 50.2 42.3 99.9 27.6 54.9 30.5 126.2 0.9 0.5 0.0 1.2 0.7 1.3 0.4 0.5 1.0 0.5 0.7 0.1 0.5 0.1 0.6 0.2 0.5 0.3 0.3 16.5 18.6 22.2 22.3 18.0 23.2 23.6 22.9 22.0 25.2 21.5 33.4 12.1 28.9 16.4 42.7 3.9 7.1 5.6 4.4 2.2 8.4 7.4 5.8 13.3 5.7 10.0 7.3 18.8 14.5 10.2 11.2 0.0 7.7 206.2 17.0 23.4 13.9 14.9 8.2 132.8 16.4 4.1 11.3 10.7 16.9 27.3 6.5 20.3 15.4 8.7 11.8 35.1 5.1 4.1 11.1 7.5 72.0 9.3 8.0 5.4 30.0 4.4 8.6 3.1 30.2 95.5 24.0 4.5 10.1 8.0 9.5 1.0 1.9 12.4 12.8 0.0 7.5 8.5 9.1 4.6 3.2 4.8 21.2 6.9 4.4 8.5 13.7 DTD2 "C14orf126, MGC9912" ENSG00000129480 "D-aminoacyl-tRNA deacylase 2" Q96FN9 14 31446036-31457506 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 35.2;Oligodendrocytes: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001117 Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA001117: AB_2666204" "unprognostic (2.56e-3)" "unprognostic (9.38e-2)" "unprognostic (1.27e-3)" "unprognostic (3.24e-2)" "unprognostic (8.45e-2)" "prognostic unfavorable (9.33e-4)" "unprognostic (3.04e-2)" "unprognostic (1.64e-1)" "unprognostic (8.74e-3)" "unprognostic (2.91e-1)" "unprognostic (5.28e-2)" "unprognostic (6.96e-2)" "unprognostic (1.24e-1)" "unprognostic (2.32e-1)" "unprognostic (3.06e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (5.74e-6)" 8.6 6.3 4.7 4.9 6.8 2.3 7.1 5.2 6.5 4.0 5.2 4.8 3.9 5.2 5.0 5.7 4.9 3.5 3.1 5.3 5.3 5.8 8.1 5.8 5.5 5.5 5.9 5.3 6.3 6.1 4.4 4.3 5.9 5.7 5.4 5.0 6.0 3.9 1.6 5.6 3.7 5.5 4.9 4.9 4.0 4.0 6.2 5.0 6.2 1.6 5.5 4.7 3.8 8.1 11.4 9.5 8.1 10.6 14.6 12.3 5.5 10.3 10.0 8.0 7.1 5.2 10.7 21.6 6.8 11.8 8.6 10.8 13.0 11.6 13.6 11.7 5.7 6.2 6.5 29.0 15.7 12.6 7.3 14.0 12.9 7.1 15.9 6.7 11.8 12.8 12.3 9.9 10.7 13.7 18.3 11.3 11.0 19.6 9.7 12.3 6.0 11.3 15.0 9.8 12.1 8.0 16.8 21.6 12.4 6.9 19.8 6.5 8.6 8.7 7.7 7.1 9.1 12.3 24.5 20.7 3.8 11.4 14.3 2.5 2.6 1.0 2.0 2.2 2.9 2.7 3.0 2.2 3.7 3.2 4.5 3.0 1.5 3.7 1.2 2.2 1.6 2.8 4.7 6.8 5.2 6.5 5.3 5.3 5.5 5.9 5.9 4.9 6.2 8.1 2.9 9.6 9.0 10.1 7.6 5.2 5.7 5.1 13.1 5.9 6.1 4.3 4.8 15.7 4.9 3.7 8.4 9.1 4.9 3.3 3.9 5.7 4.4 6.8 7.2 3.8 3.0 8.0 9.2 6.2 6.3 6.2 5.1 3.0 1.3 5.9 3.9 11.6 5.1 5.0 12.7 6.7 14.2 5.5 3.7 6.6 7.5 4.0 3.6 2.8 4.8 9.5 7.2 35.2 40.2 5.2 3.9 8.2 7.1 6.0 3.3 9.7 6.2 9.2 0.0 7.4 6.8 10.1 2.7 16.2 5.4 2.7 5.4 10.3 7.2 4.2 DTX4 "KIAA0937, RNF155" ENSG00000110042 "Deltex E3 ubiquitin ligase 4" Q9Y2E6 11 59171430-59208588 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 33.6;Oligodendrocytes: 33.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 63.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 62.8;CACO-2: 34.5;CAPAN-2: 37.7;OE19: 35.4;RT4: 95.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056760, HPA059294" Approved Approved Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA056760: AB_2683228, HPA059294: AB_2683969" "unprognostic (3.23e-2)" "unprognostic (1.57e-1)" "unprognostic (1.10e-2)" "unprognostic (4.98e-2)" "unprognostic (4.97e-2)" "unprognostic (5.03e-1)" "unprognostic (2.92e-1)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.69e-2)" "unprognostic (3.04e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (5.51e-2)" "unprognostic (2.51e-1)" "prognostic favorable (5.81e-4)" "unprognostic (2.57e-3)" 10.4 1.9 13.9 5.5 21.2 9.3 9.5 21.4 20.0 8.0 8.2 17.5 16.4 3.8 1.9 4.7 5.8 4.9 3.2 13.2 21.2 8.5 32.5 18.1 5.3 30.2 22.4 15.0 7.9 1.0 4.1 14.8 27.0 7.5 17.2 10.4 21.7 3.1 1.4 3.9 14.4 2.5 33.5 6.7 11.6 1.7 25.6 1.5 10.2 1.7 6.5 15.0 3.9 50.5 4.8 5.7 30.5 0.6 8.5 0.5 62.8 0.4 2.7 0.3 0.4 34.5 37.7 11.6 2.1 0.7 1.2 16.5 9.5 11.8 0.1 0.8 0.5 0.1 6.6 11.2 2.4 0.9 2.3 1.4 19.3 0.1 0.5 2.1 0.0 2.1 0.1 1.1 1.4 2.7 0.5 0.1 16.1 35.4 1.5 4.1 27.1 1.3 2.6 95.2 0.0 0.1 24.3 6.4 0.8 7.7 4.9 0.5 0.3 0.1 4.9 0.1 0.0 0.4 0.1 1.1 0.2 2.8 2.6 0.7 0.4 0.4 0.0 0.4 0.0 1.0 0.0 0.0 0.6 1.3 0.0 0.0 1.5 0.0 0.2 2.8 0.0 0.1 13.9 21.2 21.4 20.0 13.2 21.2 30.2 22.4 27.0 33.5 25.6 50.5 8.9 19.2 16.8 9.4 3.1 1.7 3.2 7.9 2.2 2.0 2.9 3.9 1.4 28.6 21.8 7.3 0.0 15.0 6.9 33.6 0.0 10.2 0.4 1.5 8.1 3.6 4.9 0.0 12.0 4.9 19.2 7.2 12.2 3.0 1.3 4.9 5.7 23.1 3.7 0.0 8.4 10.5 2.0 2.5 2.5 0.4 4.1 2.7 5.4 3.7 0.9 30.3 0.0 7.5 33.9 10.8 16.3 3.4 0.0 3.1 19.8 9.1 14.9 2.0 0.0 22.1 3.6 0.4 1.7 1.8 1.3 5.5 1.2 5.9 18.5 22.5 DYRK4 ENSG00000010219 "Dual specificity tyrosine phosphorylation regulated kinase 4" Q9NR20 12 4562204-4615302 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 36.7" "Group enriched" "Detected in all" 5 "Early spermatids: 392.2;Late spermatids: 393.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA028065, HPA056073" Enhanced Enhanced Vesicles No No "Cluster 14: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA028065: AB_10601212, HPA056073: AB_2683028" "unprognostic (2.50e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (3.56e-3)" "unprognostic (2.62e-1)" "unprognostic (4.07e-3)" "unprognostic (2.03e-2)" "unprognostic (4.69e-2)" "unprognostic (1.29e-1)" "unprognostic (7.13e-2)" "unprognostic (1.22e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (6.52e-6)" "unprognostic (1.86e-1)" "unprognostic (9.71e-2)" "unprognostic (1.04e-1)" "unprognostic (3.98e-2)" 2.1 4.2 3.9 3.4 4.2 4.6 6.4 5.1 7.6 5.9 4.2 5.4 4.6 5.0 17.0 4.0 5.0 4.4 4.7 4.2 4.4 3.5 4.2 4.7 5.9 4.4 4.5 5.1 3.0 5.0 3.6 6.8 4.8 5.0 6.2 7.7 3.7 7.2 2.2 4.9 4.0 5.1 4.1 6.2 3.2 36.7 4.8 4.3 9.1 4.1 5.4 4.7 2.0 5.7 2.0 3.2 3.9 4.3 5.8 7.1 4.7 2.4 4.8 5.4 5.9 0.6 3.2 6.1 0.3 6.9 3.7 4.2 3.0 4.5 4.2 4.7 6.8 4.2 1.0 3.6 16.4 3.7 3.3 4.9 9.6 3.8 12.4 10.1 7.8 6.5 1.8 6.7 4.9 4.3 3.5 9.1 5.3 1.0 1.8 0.7 2.8 2.6 6.7 1.9 0.0 1.5 0.5 2.4 3.3 8.4 1.9 3.3 0.5 6.3 4.9 0.6 3.1 1.9 2.6 3.8 3.3 5.8 3.3 0.3 1.7 0.8 0.5 1.3 0.6 4.4 0.8 0.9 1.6 3.0 0.8 0.9 0.0 0.7 3.5 0.8 0.7 0.8 3.9 4.2 5.1 7.6 4.2 4.4 4.4 4.5 4.8 4.1 4.8 5.7 13.0 12.8 16.2 11.1 15.8 8.9 13.2 31.2 14.8 20.7 21.2 30.4 23.8 7.2 19.9 16.5 10.4 15.7 16.7 5.2 31.3 25.1 392.2 14.0 22.5 15.5 5.4 12.2 10.3 27.1 12.0 17.3 14.3 13.3 17.7 19.0 8.2 9.8 49.7 13.5 10.4 75.4 14.2 16.1 9.3 393.1 15.2 18.7 16.0 9.4 14.5 19.4 13.4 14.1 16.1 20.1 14.2 31.6 22.9 16.4 7.3 35.6 13.9 21.7 6.6 15.2 17.6 23.7 39.0 20.4 7.5 9.9 12.7 40.6 17.3 11.8 DZIP3 "hRUL138, PPP1R66" ENSG00000198919 "DAZ interacting zinc finger protein 3" Q86Y13 3 108589705-108694840 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 327.4;Respiratory ciliated cells: 218.2;Spermatocytes: 351.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035066, HPA049232" Approved Approved Vesicles No No "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA035066: AB_10601549, HPA049232: AB_2680684" "unprognostic (1.14e-1)" "unprognostic (1.90e-1)" "unprognostic (7.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (2.37e-2)" "unprognostic (3.33e-1)" "unprognostic (5.16e-2)" "unprognostic (2.74e-1)" "unprognostic (3.76e-2)" "unprognostic (2.59e-3)" "unprognostic (5.38e-2)" "prognostic favorable (3.65e-4)" "unprognostic (6.06e-2)" "unprognostic (2.78e-2)" "unprognostic (5.51e-3)" "unprognostic (3.81e-2)" 5.2 9.7 15.6 4.9 19.4 4.0 5.3 11.8 18.6 5.3 22.6 5.1 3.0 7.9 10.1 3.9 18.7 5.9 11.7 18.8 18.5 10.9 4.3 6.5 10.2 13.3 14.9 10.5 5.3 7.8 24.5 4.9 12.4 9.7 4.7 29.8 3.6 7.0 12.4 3.7 3.9 5.2 10.4 8.3 6.6 34.6 15.5 8.5 12.8 16.2 8.0 5.2 3.4 15.0 9.8 8.2 24.8 14.7 10.7 10.8 8.6 6.1 12.2 10.1 13.9 12.1 6.8 18.0 12.8 6.6 20.9 3.5 13.7 5.3 21.0 6.6 6.1 8.1 3.4 8.5 6.3 3.3 4.5 11.8 2.8 9.4 11.4 10.2 6.4 10.9 8.0 8.7 19.6 8.6 8.2 3.5 15.5 5.0 6.2 10.4 20.5 1.8 8.4 4.7 17.0 16.2 9.8 1.0 11.1 21.6 15.1 2.8 7.6 9.0 13.7 1.8 5.3 9.6 6.0 34.7 6.8 2.7 11.3 6.5 0.5 1.2 4.1 0.8 5.0 6.3 4.2 5.1 0.5 4.6 3.6 4.8 0.1 10.6 1.5 1.5 6.0 1.5 15.6 19.4 11.8 18.6 18.8 18.5 13.3 14.9 12.4 10.4 15.5 15.0 7.3 12.8 12.8 86.8 14.8 7.5 8.6 16.3 9.1 67.8 9.6 8.3 45.0 4.3 26.6 33.1 327.4 21.9 17.1 4.1 13.7 12.9 28.4 106.1 16.0 8.7 52.8 11.1 145.2 9.0 8.8 18.2 9.2 9.2 8.8 30.9 7.5 4.4 9.4 77.4 103.4 6.9 34.6 5.7 7.5 59.9 17.4 5.7 7.2 37.5 10.5 32.9 11.3 79.4 80.6 8.9 4.6 17.7 9.0 6.9 4.5 20.6 218.2 33.7 19.7 16.6 17.7 351.3 112.5 4.4 7.4 14.8 29.4 35.4 7.4 5.6 ECHDC1 dJ351K20.2 ENSG00000093144 "Ethylmalonyl-CoA decarboxylase 1" Q9NTX5 6 127288712-127343609 "Enzymes, Plasma proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 230.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035445, HPA035446" Uncertain Approved Vesicles NA NA 56000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA035445: AB_10669860, HPA035446: AB_2732468" "unprognostic (9.57e-2)" "unprognostic (1.63e-2)" "unprognostic (2.46e-3)" "unprognostic (1.34e-1)" "unprognostic (4.09e-1)" "unprognostic (3.68e-2)" "unprognostic (5.03e-3)" "unprognostic (4.89e-3)" "unprognostic (4.97e-2)" "unprognostic (1.76e-1)" "unprognostic (3.99e-1)" "unprognostic (9.97e-2)" "unprognostic (8.21e-3)" "unprognostic (6.83e-2)" "unprognostic (2.86e-1)" "unprognostic (1.39e-1)" "unprognostic (1.40e-2)" 92.9 29.4 21.8 36.8 24.5 16.2 37.3 26.4 28.6 36.4 32.3 58.4 46.8 21.4 23.0 33.5 23.2 27.5 42.6 22.0 27.0 92.5 93.8 56.8 41.3 28.1 24.7 21.1 27.9 26.2 14.1 36.2 28.5 33.8 53.8 30.0 46.3 28.4 39.3 22.7 40.7 33.4 24.4 28.4 37.0 18.2 24.7 41.1 38.7 52.2 42.6 43.4 23.4 32.3 58.3 45.6 64.0 59.3 92.9 87.7 54.1 92.7 112.1 78.0 99.0 79.7 43.1 87.6 77.8 88.6 88.4 46.9 0.1 69.6 98.3 52.4 43.3 116.9 58.4 128.3 82.6 158.0 63.4 99.6 81.9 73.1 61.6 70.6 71.8 63.2 147.6 51.6 105.7 55.1 105.7 73.5 52.9 29.0 55.8 49.0 78.7 72.3 142.8 70.8 73.3 71.2 52.1 1.8 131.3 48.3 1.8 182.6 75.2 47.8 76.9 121.8 104.8 65.7 141.0 116.3 87.2 136.4 114.7 19.0 71.6 24.0 23.4 57.5 24.7 28.6 19.8 22.9 66.6 29.2 23.7 24.2 28.6 15.3 43.1 50.5 22.1 43.9 21.8 24.5 26.4 28.6 22.0 27.0 28.1 24.7 28.5 24.4 24.7 32.3 37.0 96.1 114.0 32.3 59.7 26.1 42.3 94.2 35.3 26.4 30.8 28.3 60.8 32.9 102.4 31.3 31.3 106.8 49.3 35.6 127.2 76.1 64.7 47.0 48.3 32.6 13.8 22.9 47.4 79.5 85.6 45.8 38.2 40.2 43.7 32.9 26.0 68.8 85.8 28.6 41.0 35.7 59.0 48.4 38.7 24.4 32.9 55.9 35.6 40.3 55.3 33.5 47.4 55.3 95.0 54.4 41.1 31.2 48.3 31.1 74.4 230.3 47.0 42.3 26.3 55.7 33.0 27.6 28.6 34.7 22.9 65.5 46.3 88.2 56.9 52.7 EEA1 ZFYVE2 ENSG00000102189 "Early endosome antigen 1" Q15075 12 92770637-92929331 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005861, CAB018782, HPA038158, HPA038159" Supported Supported Vesicles NA NA 20000 "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB005861: AB_2262056, CAB018782: AB_2277714, HPA038158: AB_10966710, HPA038159: AB_10962356" "unprognostic (5.38e-2)" "unprognostic (4.60e-1)" "unprognostic (2.00e-2)" "unprognostic (5.62e-2)" "unprognostic (1.62e-1)" "unprognostic (1.81e-2)" "unprognostic (6.75e-2)" "unprognostic (6.87e-2)" "unprognostic (1.31e-1)" "unprognostic (5.00e-2)" "unprognostic (2.81e-2)" "unprognostic (1.07e-1)" "unprognostic (2.68e-3)" "unprognostic (5.86e-2)" "unprognostic (2.85e-1)" "unprognostic (3.89e-2)" "unprognostic (1.65e-1)" 11.4 6.6 2.8 6.7 3.0 3.7 7.2 6.6 4.3 9.3 0.0 8.2 6.7 8.7 4.1 13.1 4.8 7.3 7.8 2.7 3.8 6.6 9.5 7.1 5.6 5.3 4.3 8.9 6.0 8.1 2.8 9.4 5.5 7.3 7.0 13.7 7.0 5.7 9.6 10.2 6.6 8.4 3.2 7.3 7.0 5.3 3.5 4.1 8.1 10.4 5.5 8.5 6.8 4.4 14.9 4.9 7.2 5.1 30.1 30.1 16.4 28.8 16.6 15.0 10.6 17.1 4.0 15.2 5.1 20.3 21.3 17.5 16.0 8.1 23.0 10.2 7.8 16.2 5.9 15.7 16.7 11.6 7.3 19.7 11.7 16.1 24.0 16.7 25.3 4.2 12.2 5.0 15.7 6.9 8.4 7.9 7.2 6.0 10.5 9.2 18.2 10.1 7.7 20.4 6.0 4.4 21.2 13.7 12.9 9.9 18.2 10.1 34.4 21.0 8.0 16.8 11.2 5.4 10.1 10.2 7.8 10.1 11.6 0.0 0.6 0.2 0.4 0.4 0.4 0.5 0.4 0.4 0.5 0.4 0.8 0.5 0.5 0.2 0.9 0.5 0.1 0.2 2.8 3.0 6.6 4.3 2.7 3.8 5.3 4.3 5.5 3.2 3.5 4.4 58.3 99.3 59.8 60.7 36.4 37.9 57.6 25.2 35.9 53.1 26.5 24.9 93.0 17.2 32.8 25.8 37.5 65.5 39.4 35.7 43.0 59.0 15.1 37.1 85.7 58.9 16.8 14.9 58.5 34.7 45.8 81.1 29.0 53.6 32.9 29.8 31.4 37.4 36.4 183.4 76.2 26.6 14.2 38.6 36.8 9.5 61.8 44.5 48.0 68.4 44.0 60.0 28.8 94.5 102.5 40.4 35.9 68.1 19.8 50.0 26.3 35.3 26.4 68.4 46.0 104.4 71.0 131.1 30.0 91.3 50.3 113.6 29.8 35.5 30.7 78.1 EEF2KMT "EFM3, FAM86A, MGC19636, SB153" ENSG00000118894 "Eukaryotic elongation factor 2 lysine methyltransferase" Q96G04 16 5084284-5097795 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Early spermatids: 189.0;Late spermatids: 393.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 104.8" "Low region specificity" "Detected in all" HPA041610 Approved Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 25: RPMI-8226 - Immune response" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA041610: AB_2677581" "unprognostic (4.50e-2)" "unprognostic (1.53e-1)" "unprognostic (8.89e-3)" "unprognostic (3.95e-2)" "unprognostic (2.01e-2)" "unprognostic (7.70e-2)" "prognostic unfavorable (8.85e-4)" "unprognostic (3.53e-1)" "unprognostic (1.37e-1)" "unprognostic (4.03e-2)" "unprognostic (9.73e-2)" "unprognostic (1.53e-1)" "unprognostic (5.24e-3)" "unprognostic (1.82e-1)" "unprognostic (2.07e-1)" "unprognostic (2.75e-2)" "prognostic unfavorable (2.35e-4)" 4.6 5.9 3.2 4.0 3.2 1.1 4.9 2.9 3.4 5.0 3.3 5.0 5.1 6.6 2.7 6.0 4.9 2.8 5.7 2.7 3.4 6.8 8.2 3.7 4.5 3.4 3.5 3.7 6.8 5.8 5.0 2.3 3.4 4.8 3.5 1.1 5.4 4.3 8.5 4.3 4.1 5.2 2.9 4.7 5.3 10.6 3.9 2.4 4.9 3.4 3.5 6.0 4.5 2.9 6.3 20.1 8.9 16.5 9.2 7.3 11.3 11.8 6.7 11.6 7.3 15.1 18.2 17.9 7.6 12.2 15.1 13.5 14.5 14.6 8.5 18.7 15.3 7.7 8.6 25.5 11.5 16.4 9.5 8.4 10.9 13.5 23.6 5.4 11.6 21.3 13.8 16.1 9.6 42.0 7.7 9.8 16.3 33.7 13.6 17.9 9.9 104.8 12.6 8.1 11.0 9.2 14.4 20.0 8.6 6.9 14.0 5.7 7.1 18.7 12.6 59.8 12.3 10.3 13.8 11.8 5.4 12.9 18.3 10.1 7.2 0.7 10.7 13.7 15.8 12.8 10.4 11.6 9.7 9.5 7.9 11.9 0.9 10.5 17.2 2.8 17.8 8.3 3.2 3.2 2.9 3.4 2.7 3.4 3.4 3.5 3.4 2.9 3.9 2.9 7.2 3.2 3.7 0.3 8.6 0.0 9.1 0.0 8.0 2.6 9.7 11.4 1.1 7.2 2.5 5.5 0.0 6.0 3.6 1.8 31.3 18.5 189.0 6.8 14.7 7.3 3.6 3.8 0.7 18.3 12.5 6.0 6.1 4.2 1.3 9.9 6.4 9.9 14.6 6.7 0.9 4.6 0.0 4.1 0.0 393.3 7.8 5.8 0.0 1.9 5.7 7.3 6.2 0.5 1.5 17.0 2.9 3.8 10.2 23.4 3.4 19.6 7.3 2.8 0.0 5.3 6.4 5.8 16.8 12.8 0.0 4.1 5.9 16.2 5.3 8.5 EIF4ENIF1 "2610509L04Rik, 4E-T, Clast4, FLJ21601" ENSG00000184708 "Eukaryotic translation initiation factor 4E nuclear import factor 1" Q9NRA8 22 31436977-31496108 "Plasma proteins, Predicted intracellular proteins" "Protein transport, RNA-mediated gene silencing, Translation regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 54.6;Late spermatids: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001619, HPA002078" Enhanced Enhanced Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA001619: AB_1078727, HPA002078: AB_1078728" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (2.40e-2)" "unprognostic (3.01e-2)" "unprognostic (1.53e-1)" "unprognostic (6.72e-2)" "unprognostic (2.28e-3)" "unprognostic (1.30e-2)" "unprognostic (4.95e-2)" "unprognostic (9.92e-2)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" "prognostic favorable (1.57e-4)" "unprognostic (2.30e-1)" "unprognostic (1.92e-1)" "unprognostic (7.32e-2)" "unprognostic (2.45e-2)" 12.5 11.9 14.3 10.4 14.8 14.3 11.9 19.7 17.3 15.9 11.4 19.4 11.4 15.0 13.0 14.0 13.8 7.8 13.2 15.3 15.0 12.3 8.4 12.1 12.6 13.6 14.7 15.0 10.5 16.7 10.8 13.6 14.3 13.5 11.5 18.0 12.1 13.2 20.2 15.7 11.8 12.1 11.6 12.3 12.3 34.7 13.8 12.9 13.5 14.5 14.9 15.6 14.3 17.3 19.8 11.6 29.4 16.0 16.1 14.2 11.7 13.7 16.8 21.4 19.8 13.4 7.0 25.3 7.9 20.7 14.3 19.1 26.9 12.5 19.7 20.2 27.0 10.3 20.0 15.4 16.7 41.0 17.9 16.6 16.9 15.8 17.8 19.5 18.4 14.8 25.4 27.0 20.3 22.4 27.8 20.3 13.5 18.3 9.5 31.1 24.5 26.0 21.7 14.7 22.6 20.9 18.9 15.4 14.5 19.4 16.4 16.1 20.5 14.3 18.6 14.4 15.5 19.3 20.4 25.1 13.7 14.8 17.1 1.3 2.4 1.2 3.4 3.0 3.5 4.8 1.8 3.3 2.2 2.0 1.8 3.2 2.0 1.0 8.1 4.4 1.4 1.9 14.3 14.8 19.7 17.3 15.3 15.0 13.6 14.7 14.3 11.6 13.8 17.3 8.4 12.8 15.2 23.2 10.6 7.4 7.3 6.2 15.4 18.0 9.6 8.9 22.7 10.0 8.5 12.9 12.5 9.8 13.8 8.6 9.8 8.9 54.6 8.0 12.8 10.2 12.0 12.4 21.0 6.4 5.5 8.1 12.2 13.0 6.3 23.1 11.0 8.9 8.0 18.5 20.5 10.8 8.2 9.5 6.2 98.9 14.6 7.5 7.2 13.1 14.5 8.1 14.4 20.1 20.2 10.2 3.6 15.4 10.3 10.7 5.7 9.4 6.3 13.7 6.6 11.8 11.0 38.7 13.3 10.7 10.5 6.7 8.2 9.0 8.1 8.0 EIF5A2 ENSG00000163577 "Eukaryotic translation initiation factor 5A2" Q9GZV4 3 170888418-170908644 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein biosynthesis, Protein transport, Translocation, Transport" "Elongation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 28.3" "Group enriched" "Detected in many" 12 "Early spermatids: 353.0;Late spermatids: 977.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029090 Approved Supported Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA029090: AB_10671359" "unprognostic (2.41e-1)" "unprognostic (2.42e-1)" "unprognostic (4.05e-1)" "unprognostic (5.75e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (7.42e-4)" "unprognostic (1.11e-3)" "unprognostic (1.47e-1)" "unprognostic (3.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (1.79e-1)" "unprognostic (2.66e-2)" "unprognostic (3.45e-2)" "unprognostic (5.92e-2)" "unprognostic (1.64e-2)" "unprognostic (4.29e-3)" 4.1 2.7 1.9 3.1 2.8 4.2 2.9 5.8 6.1 3.1 1.9 3.4 1.7 4.5 1.3 2.9 2.4 3.5 4.0 1.9 5.4 5.0 1.6 2.2 2.8 7.2 4.6 4.4 3.3 3.7 1.8 1.8 8.2 2.6 2.6 2.8 1.9 3.0 1.3 1.9 1.6 7.2 4.1 2.3 9.1 28.3 5.5 4.3 2.2 3.1 3.1 3.5 2.0 7.2 22.7 11.6 4.2 5.9 21.7 14.2 10.0 17.1 22.3 17.4 25.1 23.6 14.4 14.2 30.9 23.4 38.9 7.4 13.4 6.0 21.9 15.8 5.8 6.9 4.6 7.5 14.6 18.2 19.9 16.6 8.7 26.3 21.4 24.2 9.1 3.7 5.8 0.1 28.7 7.6 8.1 7.9 8.1 17.5 7.8 0.0 12.0 0.0 7.3 4.0 3.4 6.4 17.7 4.6 14.4 6.5 10.0 11.9 12.0 21.2 15.0 44.8 38.9 21.6 0.3 33.3 7.2 6.2 15.4 14.9 1.4 1.5 12.4 1.5 8.7 2.2 8.4 11.9 1.0 3.5 5.0 8.3 0.7 8.8 1.4 1.0 11.3 5.0 1.9 2.8 5.8 6.1 1.9 5.4 7.2 4.6 8.2 4.1 5.5 7.2 16.6 0.0 0.5 4.9 4.4 17.1 8.5 7.8 10.8 2.5 2.1 2.7 9.5 0.0 1.8 1.8 0.0 1.2 18.1 1.6 1.9 6.4 353.0 0.9 7.7 12.8 4.9 2.1 7.1 7.5 1.9 11.7 8.6 0.6 2.5 2.6 3.3 2.5 8.9 0.0 8.8 0.8 2.0 3.8 7.2 977.9 12.8 4.5 10.6 3.7 7.9 8.0 28.8 4.0 10.1 19.6 6.1 11.3 3.7 8.2 1.7 21.1 3.4 2.7 46.0 9.6 11.6 54.3 10.0 2.3 21.6 0.7 15.7 2.2 1.8 5.7 EML2 "ELP70, EMAP-2, EMAP2" ENSG00000125746 "EMAP like 2" O95834 19 45606994-45645602 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 153.1;Syncytiotrophoblasts: 101.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012757 Approved Approved Vesicles NA NA 180000 "Cluster 27: Non-specific - Gene expression" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles "HPA012757: AB_1848145" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.81e-3)" "unprognostic (1.13e-1)" "unprognostic (1.69e-2)" "unprognostic (1.16e-1)" "unprognostic (1.85e-1)" "unprognostic (3.05e-3)" "unprognostic (3.72e-1)" "unprognostic (2.75e-3)" "unprognostic (1.77e-1)" "unprognostic (2.85e-2)" "unprognostic (9.44e-2)" "unprognostic (7.48e-2)" "unprognostic (7.03e-2)" 11.2 32.7 23.2 13.6 41.7 14.1 12.9 43.2 37.6 16.4 9.7 21.3 11.5 9.1 6.8 40.2 12.0 10.9 20.4 19.5 36.1 17.5 7.9 13.6 13.4 57.6 35.4 5.2 21.1 55.1 14.3 19.8 52.8 15.8 14.4 49.0 29.0 18.3 5.7 38.6 11.9 7.1 27.9 12.9 18.9 3.5 40.3 16.5 20.9 4.9 12.5 19.5 24.9 57.9 47.6 16.2 3.2 1.1 25.0 13.6 17.4 29.2 37.0 12.6 14.8 6.2 39.5 14.6 17.0 15.4 4.0 39.7 6.0 57.4 4.0 56.7 15.0 5.7 19.5 12.4 47.1 18.5 13.4 21.1 74.5 15.1 74.1 10.5 9.4 28.0 18.3 38.5 10.0 49.9 10.3 4.2 1.9 75.7 14.3 2.3 5.6 18.9 33.3 61.2 17.8 3.3 16.4 32.0 22.1 17.0 18.7 18.9 15.1 0.0 5.4 4.8 0.3 66.2 43.9 7.9 20.4 20.9 38.7 7.8 3.7 5.7 6.5 4.8 5.1 5.5 4.4 6.7 4.4 2.2 2.9 3.9 1.0 2.6 5.2 6.4 5.8 3.9 23.2 41.7 43.2 37.6 19.5 36.1 57.6 35.4 52.8 27.9 40.3 57.9 10.6 3.2 13.1 8.5 15.7 18.6 42.9 40.3 27.3 32.2 13.2 14.2 9.0 14.3 25.5 35.0 14.6 66.4 24.5 34.1 37.2 16.8 72.1 28.6 9.0 13.8 17.5 5.5 29.7 20.8 20.4 7.6 38.7 20.1 19.1 6.7 20.3 6.4 15.8 28.6 46.0 32.6 26.4 8.8 9.6 27.0 4.1 8.7 19.6 5.6 13.1 16.4 12.3 15.1 68.0 17.9 29.1 7.2 25.0 23.7 11.0 7.5 40.7 153.1 0.0 6.8 16.4 3.5 6.1 29.6 14.3 101.0 23.2 39.1 31.9 41.9 EMP1 "CL-20, TMP" ENSG00000134531 "Epithelial membrane protein 1" P54849 12 13196723-13219941 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2255.1;vagina: 819.5" "Cell type enhanced" "Detected in many" "Adipocytes: 835.5;Basal keratinocytes: 694.1;Endothelial cells: 662.2;Squamous epithelial cells: 888.5;Suprabasal keratinocytes: 687.6;Urothelial cells: 1193.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 3.4" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 1166.6;fHDF/TERT166: 861.7;HaCaT: 766.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 4.5;spinal cord: 16.0" HPA046912 Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA046912: " "unprognostic (1.40e-2)" "unprognostic (7.30e-2)" "unprognostic (8.01e-2)" "unprognostic (1.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (8.41e-3)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (7.46e-4)" "unprognostic (2.98e-1)" "unprognostic (4.84e-2)" "unprognostic (3.05e-2)" "unprognostic (3.45e-2)" "unprognostic (3.25e-1)" "prognostic unfavorable (9.69e-8)" 536.6 42.0 18.6 63.9 20.2 20.7 166.7 18.2 28.4 463.2 14.2 100.7 39.5 61.6 12.5 2255.1 84.8 205.8 121.8 17.7 46.5 93.9 35.1 177.9 11.4 29.5 22.9 21.8 86.8 20.6 29.9 76.9 27.2 39.6 56.4 5.5 377.8 20.3 27.0 150.9 41.8 149.2 25.1 26.2 48.5 9.2 20.8 28.4 133.5 35.6 165.4 205.7 819.5 22.1 373.5 19.4 9.1 1.9 563.2 1166.6 1.5 269.6 489.4 135.7 172.3 2.7 612.6 2.2 187.3 861.7 60.0 766.6 10.8 35.7 182.9 7.2 0.8 1.2 61.9 0.2 135.6 2.6 2.1 369.8 50.9 432.7 126.4 107.3 316.8 0.2 2.0 6.2 325.4 1.6 0.8 8.3 6.6 69.8 62.3 1.0 37.1 3.4 396.4 4.4 0.3 0.3 120.1 17.4 211.9 69.9 3.1 2.2 349.8 302.2 106.7 287.0 146.8 1.5 4.1 2.5 441.2 2.2 363.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.6 20.2 18.2 28.4 17.7 46.5 29.5 22.9 27.2 25.1 20.8 22.1 835.5 205.1 88.5 8.1 3.7 694.1 362.3 34.8 223.7 0.1 316.5 91.7 12.9 27.1 166.8 18.4 0.0 1.2 7.6 481.5 15.6 28.7 0.8 76.0 167.6 662.2 47.6 0.0 0.9 4.4 1.8 470.5 62.2 160.3 50.4 0.1 157.1 2.2 39.8 0.0 0.4 13.5 6.1 37.1 481.2 2.1 69.6 105.8 473.2 7.5 7.0 2.4 0.0 0.5 0.2 62.2 343.0 109.4 12.7 413.0 48.6 0.5 60.2 0.4 6.6 202.1 170.1 1.1 0.9 888.5 687.6 1.1 23.0 5.1 26.6 1193.8 ENTPD4 "KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase" ENSG00000197217 "Ectonucleoside triphosphate diphosphohydrolase 4" Q9Y227 8 23385783-23457695 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017655 Supported Approved Vesicles NA NA 82000 "Cluster 2: Granulocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" Vesicles "HPA017655: AB_1848181" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (5.06e-2)" "unprognostic (7.86e-3)" "unprognostic (2.00e-2)" "unprognostic (2.99e-3)" "unprognostic (2.07e-2)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" "unprognostic (6.62e-2)" "unprognostic (3.72e-2)" 16.3 11.5 8.6 24.2 10.5 30.5 14.8 11.1 16.2 17.0 8.1 19.8 18.1 16.8 17.3 12.6 13.7 14.6 21.2 10.8 12.3 12.2 13.7 20.0 29.3 13.1 9.2 13.5 21.4 27.2 18.3 17.2 12.8 16.8 20.3 32.7 22.0 13.4 15.2 12.4 26.2 16.5 7.6 25.4 20.3 19.9 12.5 14.5 14.7 15.9 29.8 16.7 16.6 11.6 20.8 28.7 34.0 23.5 29.0 36.8 35.0 33.1 30.4 21.3 33.2 40.3 26.4 35.5 22.9 32.8 32.9 24.5 15.8 29.0 40.3 8.6 11.5 18.4 18.1 14.2 23.7 9.8 34.8 22.8 34.7 28.4 29.9 51.9 31.2 26.7 13.2 30.6 36.4 9.3 14.8 11.9 20.1 26.2 10.2 14.3 34.6 10.8 27.0 24.1 27.2 26.6 12.0 17.0 23.7 67.0 12.9 13.6 38.6 39.1 38.3 43.7 24.1 24.7 11.5 45.5 51.3 11.5 39.4 17.0 5.7 13.4 7.4 8.6 8.8 8.7 7.3 8.1 7.5 6.5 9.2 7.3 14.4 4.8 7.0 6.8 6.3 6.9 8.6 10.5 11.1 16.2 10.8 12.3 13.1 9.2 12.8 7.6 12.5 11.6 15.9 19.2 34.5 10.7 25.8 6.5 12.0 17.6 8.6 32.1 11.4 8.6 24.6 7.2 27.3 14.7 14.6 16.1 33.4 25.1 0.0 15.6 8.6 13.6 21.6 15.8 17.3 10.3 31.4 16.9 16.9 16.9 23.9 23.9 17.7 18.9 12.1 11.5 12.3 47.1 37.4 19.7 20.3 14.2 15.5 19.2 7.2 18.2 12.4 19.7 19.4 15.2 18.6 23.1 23.1 21.8 13.3 8.6 46.9 18.9 18.8 5.0 15.0 35.9 13.1 14.3 14.6 21.5 22.8 9.5 5.5 20.2 21.3 11.7 12.4 18.9 EPHX4 "ABHD7, EH4, EPHXRP, FLJ90341" ENSG00000172031 "Epoxide hydrolase 4" Q8IUS5 1 92029985-92063538 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.9;choroid plexus: 5.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 55.3;Inhibitory neurons: 32.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 12.1" "Lineage enriched" "Detected in single" 21 "T-cells: 12.1" "Cell line enhanced" "Detected in some" "A-431: 15.4;CAPAN-2: 13.0;EFO-21: 25.9;RPTEC TERT1: 36.1;U-251 MG: 10.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035067 Uncertain Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA035067: AB_10601465" "unprognostic (1.27e-1)" "unprognostic (4.17e-2)" "unprognostic (6.76e-3)" "unprognostic (6.10e-8)" "prognostic unfavorable (9.43e-4)" "unprognostic (5.36e-3)" "unprognostic (2.72e-4)" "unprognostic (4.85e-2)" "unprognostic (9.44e-3)" "unprognostic (7.93e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (2.53e-1)" "unprognostic (6.36e-6)" "unprognostic (6.93e-3)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.25e-1)" 0.5 0.5 4.0 0.5 9.2 0.0 1.4 1.9 10.9 0.9 5.7 0.6 0.6 0.6 0.5 0.8 0.4 0.4 0.5 6.9 2.3 0.4 0.0 0.6 0.2 3.1 2.3 0.1 0.0 0.4 1.1 0.8 3.1 0.9 0.5 2.1 0.2 1.8 0.1 0.5 0.4 1.1 1.8 0.0 0.3 1.2 2.8 0.0 1.8 0.1 0.2 0.7 0.2 5.5 15.4 0.5 2.9 0.0 0.0 0.0 0.7 0.3 5.5 0.5 0.3 0.0 13.0 0.0 25.9 0.0 3.9 0.2 0.5 1.2 0.5 0.0 8.0 0.0 0.1 0.0 0.2 1.1 0.0 0.9 0.7 0.0 0.0 9.4 4.5 0.0 0.1 0.0 0.4 0.9 2.2 0.6 2.8 0.0 5.2 0.5 0.3 0.0 36.1 3.0 1.8 2.2 9.1 0.0 2.9 0.2 0.0 2.2 0.2 0.0 0.1 0.0 10.9 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.1 0.0 2.0 0.1 1.4 3.0 0.0 0.0 0.3 2.8 0.0 0.5 0.0 0.0 0.0 1.5 4.0 9.2 1.9 10.9 6.9 2.3 3.1 2.3 3.1 1.8 2.8 5.5 2.0 0.0 0.0 4.9 0.0 0.1 0.1 2.0 0.0 2.0 6.7 4.6 1.0 0.0 1.5 0.0 2.1 0.4 3.2 0.1 0.0 0.4 1.7 1.0 0.1 6.2 0.0 0.0 55.3 0.9 0.7 0.3 0.0 1.3 0.0 0.3 0.4 0.0 0.2 1.7 32.5 0.0 0.0 0.0 0.4 0.1 0.0 0.2 3.6 4.7 0.1 8.6 0.0 5.5 2.7 5.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.6 0.0 0.1 0.8 6.0 0.7 0.1 0.4 0.0 1.1 0.2 0.3 0.3 EPN2 "EHB21, KIAA1065" ENSG00000072134 "Epsin 2" O95208 17 19215615-19336715 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Oligodendrocyte precursor cells: 868.6;Oligodendrocytes: 258.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.9;eosinophil: 29.0;neutrophil: 9.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 29.0" "Cell line enhanced" "Detected in many" "SuSa: 127.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049809, HPA053360" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA049809: AB_2680893, HPA053360: AB_2682126" "unprognostic (1.38e-2)" "unprognostic (2.54e-2)" "unprognostic (2.58e-2)" "unprognostic (2.09e-1)" "unprognostic (1.94e-1)" "unprognostic (8.12e-3)" "unprognostic (6.73e-3)" "unprognostic (1.43e-1)" "unprognostic (8.89e-2)" "unprognostic (4.58e-3)" "unprognostic (3.42e-2)" "unprognostic (1.57e-1)" "prognostic favorable (9.13e-5)" "unprognostic (1.32e-1)" "unprognostic (9.40e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (8.15e-5)" 20.5 13.9 62.1 9.7 64.9 11.5 16.7 50.4 62.8 36.3 32.7 28.3 9.6 29.5 11.5 40.3 26.6 14.6 32.5 62.6 56.2 21.3 9.3 18.6 6.5 61.6 63.6 22.5 14.6 15.3 18.1 21.6 57.5 23.6 9.5 19.1 17.9 23.4 22.4 50.1 13.3 22.5 46.6 14.3 15.9 19.7 63.6 4.7 17.8 17.0 8.4 27.0 33.8 91.6 31.3 30.4 43.9 19.2 22.8 36.3 34.5 29.4 18.9 17.9 15.3 20.2 9.2 4.9 28.2 29.5 16.8 29.0 19.8 22.1 21.9 23.6 21.2 3.2 20.3 9.2 23.7 1.4 13.1 20.5 19.5 28.3 22.7 23.2 38.8 6.6 8.6 3.9 15.8 22.5 1.3 2.1 11.1 41.3 19.8 7.1 18.8 8.1 21.0 8.6 13.0 28.8 20.9 13.9 14.7 127.9 21.0 4.0 35.6 19.7 22.3 30.9 12.9 6.7 4.3 3.9 54.0 0.5 31.1 10.9 1.3 29.0 1.6 0.8 1.2 3.0 1.1 1.3 0.5 3.4 1.3 1.2 9.0 0.7 1.0 0.6 1.0 0.7 62.1 64.9 50.4 62.8 62.6 56.2 61.6 63.6 57.5 46.6 63.6 91.6 60.0 54.5 29.3 74.4 13.7 24.1 36.6 21.2 43.9 68.3 32.8 33.4 44.5 25.8 25.0 38.6 47.9 27.6 3.3 7.2 27.4 22.5 36.8 69.2 35.0 42.5 6.0 13.5 51.3 8.4 39.8 36.1 15.8 40.6 14.0 37.3 15.0 10.4 8.4 35.3 45.0 16.8 10.2 5.1 6.2 72.7 46.6 5.9 5.4 54.4 1.6 38.3 2.1 868.6 258.3 23.3 14.9 39.5 14.4 32.0 7.0 14.2 43.2 82.3 26.3 50.5 63.7 45.8 38.3 63.9 48.9 21.9 7.4 35.0 7.8 40.1 EPS15L1 eps15R ENSG00000127527 "Epidermal growth factor receptor pathway substrate 15 like 1" Q9UBC2 19 16355239-16472085 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019237, HPA055309" Approved Approved Vesicles NA NA 110000 "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA019237: AB_1848223, HPA055309: AB_2682780" "unprognostic (3.06e-2)" "unprognostic (3.33e-3)" "unprognostic (2.19e-1)" "unprognostic (6.45e-3)" "unprognostic (1.35e-1)" "unprognostic (8.64e-2)" "unprognostic (2.58e-3)" "unprognostic (5.12e-2)" "unprognostic (1.07e-3)" "unprognostic (7.54e-2)" "unprognostic (5.21e-2)" "unprognostic (1.81e-2)" "prognostic favorable (8.10e-5)" "unprognostic (2.47e-1)" "unprognostic (9.59e-2)" "unprognostic (2.14e-1)" "unprognostic (3.32e-1)" 15.3 17.6 33.4 11.8 32.4 23.6 14.2 39.6 40.5 22.4 21.5 17.0 8.3 18.1 5.9 25.2 18.7 9.6 42.4 35.6 29.1 20.5 17.9 14.6 13.9 29.3 33.4 19.1 15.5 18.2 22.6 13.9 30.8 19.5 9.2 14.0 14.9 12.9 67.6 23.3 14.3 14.1 23.5 19.8 16.8 22.9 41.0 11.8 17.5 25.7 13.0 17.6 19.7 27.6 27.3 12.8 25.8 20.4 27.4 21.1 40.3 17.8 14.9 28.8 25.1 15.3 18.2 29.2 30.4 26.1 22.8 26.6 36.3 20.8 25.1 15.8 36.8 24.7 17.4 29.8 27.7 22.8 26.7 17.6 21.1 31.9 22.3 28.6 23.6 24.5 20.1 31.2 24.5 53.9 25.4 32.5 17.7 36.4 41.7 32.2 12.5 24.3 19.8 27.9 23.3 15.3 18.6 17.5 17.7 19.2 58.3 21.3 24.5 18.2 12.2 57.3 31.4 8.8 19.4 27.7 20.2 31.9 24.5 53.5 11.9 35.9 11.1 12.0 10.5 20.8 9.8 12.0 9.2 19.3 10.1 7.8 56.2 19.1 14.4 8.6 10.7 9.0 33.4 32.4 39.6 40.5 35.6 29.1 29.3 33.4 30.8 23.5 41.0 27.6 10.8 9.6 9.8 62.3 22.1 16.6 14.0 12.0 12.0 30.7 9.5 8.1 20.4 7.2 10.9 9.2 50.1 21.7 30.8 11.7 9.8 11.0 74.9 10.7 13.0 11.8 11.3 13.9 49.7 5.7 19.7 16.0 16.3 12.1 12.0 22.3 11.0 8.2 20.0 11.8 63.4 10.7 24.4 10.6 14.8 15.1 18.6 13.8 3.6 30.9 13.0 9.9 34.0 36.2 35.6 9.3 9.1 20.3 18.7 15.0 9.0 12.9 14.7 25.9 19.7 20.3 13.9 18.5 16.7 22.3 24.4 10.9 15.8 18.7 9.8 22.2 EPS8L3 "FLJ21522, MGC16817" ENSG00000198758 "EPS8 like 3" Q8TE67 1 109750080-109764027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "gallbladder: 35.7;intestine: 142.1;stomach 1: 50.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 254.4;Gastric mucus-secreting cells: 80.5;Intestinal goblet cells: 103.4;Late spermatids: 144.6;Paneth cells: 257.8;Proximal enterocytes: 285.3;Undifferentiated cells: 112.6" "Group enriched" "Detected in many" 6 "colorectal cancer: 52.5;pancreatic cancer: 29.7;stomach cancer: 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 15.6;CAPAN-2: 14.4;Hep G2: 36.2;OE19: 67.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030998 Approved Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA030998: AB_2673691" "unprognostic (1.73e-3)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "unprognostic (2.76e-2)" "unprognostic (2.48e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (4.13e-5)" "unprognostic (5.55e-3)" "unprognostic (3.71e-2)" "unprognostic (2.09e-1)" "unprognostic (2.33e-1)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.87e-3)" "unprognostic (3.89e-1)" "prognostic favorable (1.82e-4)" 0.0 0.0 0.1 10.8 0.0 0.0 0.2 0.0 0.0 1.3 0.0 77.1 141.8 0.2 0.9 0.1 0.1 35.7 0.1 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.1 77.1 0.0 0.0 0.2 0.0 0.0 142.1 2.9 0.0 0.0 50.7 2.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.6 14.4 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 67.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 14.3 0.3 0.0 0.0 0.0 0.0 254.4 0.0 11.6 28.0 0.7 0.1 0.3 51.4 0.0 0.0 23.9 0.0 0.0 80.5 1.0 4.5 0.0 0.0 0.2 0.0 0.0 0.0 103.4 0.0 0.0 0.0 144.6 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.5 257.8 0.4 0.3 0.0 285.3 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.4 0.6 112.6 1.8 EREG ER ENSG00000124882 Epiregulin O14944 4 74365145-74388749 "Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "bone marrow: 129.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 179.1;Kupffer cells: 133.9;Langerhans cells: 171.1;Macrophages: 570.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 270.0;CAPAN-2: 76.7;hTEC/SVTERT24-B: 83.7;U-2197: 181.4;U-87 MG: 307.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054373 Approved Vesicles "Secreted to blood" NA NA 46000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" Vesicles "HPA054373: " "unprognostic (1.26e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (4.56e-3)" "unprognostic (3.94e-2)" "unprognostic (2.24e-3)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.07e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (6.57e-5)" "unprognostic (2.94e-1)" "unprognostic (1.70e-6)" "unprognostic (2.42e-2)" "unprognostic (1.13e-2)" "unprognostic (6.59e-3)" "unprognostic (3.16e-3)" 4.5 0.0 0.3 10.3 0.3 129.0 2.5 0.2 0.5 1.9 0.2 2.0 0.2 0.2 0.2 12.6 0.8 5.7 0.7 0.3 0.1 0.1 0.2 2.7 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.6 0.4 0.1 3.4 0.1 1.3 0.0 0.2 9.3 1.6 3.0 0.0 0.5 0.2 0.1 0.6 0.1 0.1 0.0 1.0 4.9 4.0 0.3 1.4 41.1 0.0 0.0 3.8 6.6 0.1 9.2 270.0 2.6 1.6 32.5 76.7 0.0 44.1 0.0 20.1 2.4 0.0 59.3 2.7 0.0 0.0 1.2 1.6 1.2 1.1 0.1 0.1 3.9 20.2 83.7 43.5 0.0 0.0 0.0 0.1 0.5 0.2 0.4 0.1 0.1 0.1 0.2 0.6 0.1 0.0 0.1 0.6 1.6 0.0 0.0 27.0 0.2 0.0 0.0 0.1 0.0 0.0 1.6 0.6 181.4 0.0 0.0 0.0 0.2 307.0 0.0 0.2 0.4 0.2 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.5 0.3 0.1 0.2 0.1 0.4 0.0 0.6 0.3 4.9 6.4 7.2 0.0 5.7 5.4 5.6 179.1 4.0 0.0 24.4 2.3 18.2 5.7 82.4 0.0 0.0 0.4 2.2 56.3 0.0 1.8 3.7 2.4 0.7 2.5 3.6 17.0 0.1 0.2 0.7 4.4 0.5 3.9 7.0 0.1 0.4 1.9 26.8 0.0 1.8 38.2 16.2 133.9 171.1 1.0 0.3 570.7 7.2 0.0 23.2 0.0 0.0 0.0 0.0 0.8 27.1 0.0 11.7 2.5 32.4 0.2 41.9 0.0 0.0 2.5 3.1 0.5 0.3 3.8 9.2 0.7 3.3 0.2 33.1 7.4 ERV3-1 "envR, ERV-R, ERV3, H-PLK, HERV-R" ENSG00000213462 "Endogenous retrovirus group 3 member 1, envelope" Q14264 7 64990356-65006743 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 27.7" "HPA017209, HPA046508" Enhanced Approved Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA017209: AB_2732419, HPA046508: AB_2732525" "unprognostic (2.74e-2)" "unprognostic (1.84e-1)" "unprognostic (2.11e-1)" "unprognostic (1.27e-2)" "unprognostic (4.48e-1)" "unprognostic (2.03e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" "unprognostic (4.05e-3)" "unprognostic (3.55e-1)" "unprognostic (1.57e-2)" "unprognostic (4.45e-2)" "unprognostic (4.27e-3)" "unprognostic (2.11e-1)" "unprognostic (2.19e-1)" "unprognostic (9.39e-2)" "unprognostic (1.88e-2)" 22.8 33.0 4.8 8.5 4.5 9.3 15.0 4.1 6.4 10.0 5.1 5.7 3.5 10.0 32.5 15.2 8.0 16.4 6.2 4.7 6.2 4.8 3.2 9.7 5.7 6.2 7.9 7.3 5.3 15.3 8.2 13.4 5.4 7.3 5.7 13.5 12.1 7.5 3.6 12.3 4.5 7.6 4.8 6.9 6.3 8.7 5.9 6.6 7.6 1.8 7.4 6.2 11.5 5.1 3.3 1.0 17.4 27.7 11.3 4.7 12.4 5.7 6.3 2.0 4.6 1.2 20.5 5.5 5.3 2.2 4.0 3.9 2.6 1.5 3.2 4.1 1.5 2.8 1.6 11.5 1.0 6.7 3.7 5.1 1.6 1.8 0.6 10.4 11.6 6.0 12.7 10.3 8.1 8.1 4.9 5.0 5.1 10.8 1.2 11.4 0.7 3.7 3.5 6.8 3.6 16.8 6.2 1.9 0.7 18.9 4.7 16.4 9.2 6.7 1.0 5.1 2.8 3.2 7.8 1.6 5.7 20.8 4.1 0.0 1.0 2.4 0.6 1.8 0.5 0.4 0.1 0.4 0.8 0.5 0.3 0.4 7.0 1.1 0.5 0.4 1.2 0.6 4.8 4.5 4.1 6.4 4.7 6.2 6.2 7.9 5.4 4.8 5.9 5.1 7.1 3.2 13.1 17.9 32.5 4.2 15.6 17.0 7.4 24.8 13.7 10.4 2.1 24.3 25.5 16.5 29.2 16.5 21.6 4.4 9.8 14.4 7.3 6.2 8.6 10.9 13.8 19.4 12.2 17.9 12.7 8.3 12.8 5.9 8.2 20.4 13.6 3.6 9.7 18.5 13.0 9.1 16.2 21.8 16.5 4.8 11.5 19.8 10.6 14.0 16.7 11.3 36.0 24.1 14.0 17.6 7.8 9.8 10.0 12.5 15.4 4.9 14.0 21.4 6.6 7.6 8.7 12.2 11.8 8.6 5.7 40.2 20.5 10.7 6.7 31.1 ESPN DFNB36 ENSG00000187017 Espin B1AK53 1 6424776-6461367 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing Actin-binding "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 129.1;retina: 117.8;testis: 145.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 175.5;Early spermatids: 137.5;Late spermatids: 461.6;Muller glia cells: 272.5;Paneth cells: 186.3;Proximal enterocytes: 512.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebellum: 13.4;thalamus: 6.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 48.9;Hep G2: 81.5;SK-BR-3: 160.1;T-47d: 53.6" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 2.6" "HPA028674, HPA060220" Enhanced Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA028674: AB_10601316, HPA060220: AB_2684224" "unprognostic (5.06e-2)" "unprognostic (1.18e-2)" "unprognostic (2.69e-1)" "unprognostic (1.28e-1)" "unprognostic (2.19e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (2.28e-1)" "unprognostic (1.16e-1)" "unprognostic (5.71e-2)" "unprognostic (7.48e-3)" "unprognostic (5.53e-2)" "unprognostic (6.26e-3)" "unprognostic (5.51e-2)" "unprognostic (1.16e-1)" "unprognostic (3.04e-2)" "unprognostic (1.17e-2)" 0.6 5.7 0.4 2.6 1.0 28.0 9.2 13.4 1.0 30.3 0.2 28.2 90.4 2.4 39.9 34.3 18.6 0.3 0.9 0.4 1.7 63.4 129.1 3.2 0.3 0.6 1.3 0.4 0.9 26.8 42.1 0.9 1.1 10.0 6.8 117.8 9.4 6.2 0.8 91.7 89.5 0.8 0.3 0.9 2.7 145.3 6.1 1.6 0.4 0.0 1.7 1.3 22.3 0.5 14.1 0.7 0.6 0.1 0.0 0.0 48.9 0.0 0.0 0.2 0.0 29.9 1.5 0.5 6.5 0.0 0.1 32.6 2.3 0.1 0.0 2.0 0.7 0.4 0.7 81.5 0.0 0.6 2.7 0.1 0.6 0.0 0.0 0.0 0.0 1.0 17.6 0.0 0.0 28.2 0.2 1.0 0.6 3.8 12.2 0.0 0.4 10.9 0.2 0.1 21.0 0.7 3.7 160.1 5.0 0.3 53.6 7.4 15.6 0.1 0.8 0.6 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 1.0 13.4 1.0 0.4 1.7 0.6 1.3 1.1 0.3 6.1 0.5 0.2 0.0 0.6 0.0 0.8 7.8 2.4 4.5 12.5 5.6 10.7 3.9 1.4 11.5 3.8 9.2 68.8 3.0 0.2 175.5 13.7 0.2 137.5 19.1 0.9 0.8 6.0 8.2 0.2 3.1 0.5 0.3 5.6 12.4 0.0 0.0 3.9 109.4 0.2 0.0 0.2 36.3 8.2 3.2 0.9 461.6 3.7 1.5 0.0 0.0 0.0 272.5 0.0 0.0 0.1 0.1 186.3 2.2 0.0 1.6 512.1 102.2 9.0 72.5 0.0 0.0 0.2 12.3 3.9 17.6 22.7 6.6 1.5 0.0 35.3 2.9 EXOC2 "FLJ11026, SEC5L1, Sec5p" ENSG00000112685 "Exocyst complex component 2" Q96KP1 6 485154-693139 "Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 75.8;Inhibitory neurons: 80.1;Microglial cells: 68.4;Oligodendrocytes: 73.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032093 Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA032093: AB_10611964" "unprognostic (1.61e-1)" "unprognostic (4.69e-1)" "unprognostic (1.52e-1)" "unprognostic (9.32e-2)" "unprognostic (1.91e-2)" "unprognostic (2.48e-1)" "unprognostic (1.82e-3)" "unprognostic (1.34e-1)" "unprognostic (1.29e-1)" "unprognostic (1.30e-1)" "unprognostic (5.32e-2)" "unprognostic (2.02e-1)" "unprognostic (8.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (2.20e-1)" 10.2 8.3 11.0 11.5 11.7 6.6 10.9 11.4 11.2 10.1 11.6 9.1 8.6 8.7 5.2 12.2 6.5 8.9 11.6 11.2 11.5 9.3 10.3 11.3 13.4 11.6 11.6 7.8 6.6 11.6 8.2 18.0 12.5 7.9 10.0 13.4 8.0 7.9 10.1 11.8 9.3 9.2 11.0 13.1 8.9 16.1 11.3 18.6 14.2 10.4 14.1 10.8 9.1 14.4 21.0 15.2 26.0 28.5 23.2 20.8 15.7 18.5 21.5 21.7 25.8 20.4 11.0 15.5 44.0 22.3 32.7 17.7 29.2 32.2 25.7 48.4 30.9 19.8 18.5 20.4 29.1 21.2 18.8 18.1 25.9 15.5 18.0 21.4 36.9 30.0 39.4 11.1 27.3 18.1 28.6 20.6 26.4 18.6 15.1 26.6 22.5 31.3 19.5 22.4 25.4 14.9 14.8 9.0 29.1 48.4 23.2 12.9 54.1 19.6 14.1 24.6 17.4 27.2 56.8 16.4 19.8 17.4 61.0 11.6 9.0 10.2 17.1 11.0 20.9 13.5 17.2 18.3 14.1 14.5 16.2 15.7 2.8 14.8 17.7 11.1 21.1 14.4 11.0 11.7 11.4 11.2 11.2 11.5 11.6 11.6 12.5 11.0 11.3 14.4 12.6 3.2 14.5 35.6 15.9 4.8 3.8 6.2 6.2 9.0 10.1 9.3 8.6 2.8 6.5 5.5 8.4 16.0 18.5 6.1 7.9 6.2 11.0 7.3 7.0 11.1 2.4 8.2 75.8 5.1 7.1 7.6 6.1 8.2 5.1 11.8 8.6 8.2 10.0 8.4 80.1 6.8 12.2 9.0 5.8 3.8 6.8 8.7 5.4 68.4 10.8 4.6 13.4 49.3 73.4 6.9 5.1 9.1 11.3 6.4 4.1 8.2 9.0 9.3 0.0 7.3 8.9 21.8 17.5 9.9 7.7 12.9 18.3 7.4 5.9 6.0 F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186266189-186289681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 243.2" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 27.6;Hepatocytes: 75.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 16.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "Hep G2: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA039808 Approved Vesicles "Secreted to blood" NA NA 4400000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA039808: AB_2676693" "unprognostic (1.28e-1)" "unprognostic (3.15e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.88e-1)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "unprognostic (1.85e-3)" "unprognostic (2.91e-2)" "unprognostic (7.65e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.2 0.0 0.2 17.1 0.2 0.1 0.0 0.0 13.1 0.0 0.2 0.0 27.6 243.2 8.4 0.0 0.0 0.3 0.3 58.9 0.0 0.2 0.0 0.1 0.0 0.1 0.7 0.0 0.2 0.7 0.0 8.7 0.0 0.0 0.1 0.8 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.2 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 27.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.3 2.5 1.8 0.0 0.0 0.2 0.3 11.7 2.3 0.0 0.0 0.0 0.1 0.0 5.3 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 75.7 0.0 0.0 0.6 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.0 1.1 5.5 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 F3 "CD142, TF" ENSG00000117525 "Coagulation factor III, tissue factor" P13726 1 94529173-94541759 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Blood coagulation, Hemostasis" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 902.0;Exocrine glandular cells: 464.1;Pancreatic endocrine cells: 1755.7;Peritubular cells: 530.7;Urothelial cells: 497.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 1062.0;HaCaT: 490.7;HBEC3-KT: 1270.5;U-2197: 473.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009438, HPA049292, HPA069132" Uncertain Approved Vesicles "Secreted to blood" NA NA 603000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB009438: AB_668005, HPA049292: AB_2680701, HPA069132: AB_2686092" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (8.04e-2)" "unprognostic (1.64e-1)" "unprognostic (2.69e-2)" "unprognostic (1.23e-3)" "unprognostic (4.93e-2)" "unprognostic (8.00e-2)" "unprognostic (5.88e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.02e-8)" "unprognostic (4.84e-2)" "unprognostic (4.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.08e-1)" 118.2 21.3 53.1 28.8 69.9 4.1 70.1 53.2 74.4 48.0 44.1 52.2 36.8 61.1 44.2 41.3 89.9 59.6 36.8 54.0 62.7 18.0 5.1 59.8 12.9 77.7 62.6 114.8 96.5 17.2 81.2 133.4 57.1 56.8 42.1 72.6 93.3 60.4 7.6 56.0 47.3 10.7 60.8 7.2 42.6 34.6 62.0 5.6 62.6 9.9 14.9 65.4 73.0 55.4 1062.0 1.8 2.2 0.5 108.0 53.1 57.2 147.0 87.6 155.4 167.9 18.6 220.6 0.0 73.3 183.5 33.4 490.7 13.2 1270.5 254.4 0.9 1.6 0.0 35.0 3.3 35.9 0.7 0.6 91.9 28.2 73.8 356.5 293.7 1.1 1.1 0.9 0.8 110.0 1.8 1.5 22.3 9.8 6.8 2.2 1.2 10.3 0.5 19.8 3.2 1.3 2.6 117.4 48.3 3.6 29.6 1.3 13.9 0.3 93.7 2.5 473.0 44.6 0.9 1.3 0.9 71.9 5.7 3.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 53.1 69.9 53.2 74.4 54.0 62.7 77.7 62.6 57.1 60.8 62.0 55.4 9.4 131.4 243.3 196.6 0.7 16.3 902.0 359.6 2.2 3.6 29.6 20.4 26.4 18.6 380.3 14.7 0.0 16.5 0.6 20.9 0.0 133.5 8.6 61.3 125.0 13.2 13.1 0.0 0.4 464.1 6.0 125.3 23.0 123.0 2.5 38.1 7.5 0.4 6.1 3.3 4.6 70.3 65.1 2.8 5.2 14.5 281.1 9.1 3.6 45.9 2.1 340.6 0.0 15.6 1.2 1755.7 15.5 530.7 1.2 121.6 10.1 0.4 92.0 16.1 6.6 39.3 76.7 1.7 4.4 6.4 7.5 7.7 7.3 7.9 14.3 497.9 FAM114A2 "133K02, C5orf3" ENSG00000055147 "Family with sequence similarity 114 member A2" Q9NRY5 5 153990148-154038936 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035869, HPA035870" Approved Approved Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA035869: AB_10669534, HPA035870: AB_10673222" "unprognostic (1.81e-1)" "unprognostic (2.65e-1)" "unprognostic (3.45e-2)" "unprognostic (3.27e-1)" "unprognostic (7.99e-2)" "unprognostic (8.21e-2)" "unprognostic (5.18e-3)" "unprognostic (6.70e-2)" "unprognostic (1.92e-2)" "unprognostic (2.66e-1)" "unprognostic (9.70e-3)" "unprognostic (4.37e-1)" "unprognostic (7.80e-2)" "unprognostic (1.38e-3)" "unprognostic (4.17e-2)" "unprognostic (5.90e-3)" "unprognostic (2.85e-2)" 14.1 12.6 7.6 13.8 7.7 9.1 12.6 7.1 7.7 10.7 9.3 9.9 12.1 10.8 16.6 13.4 9.6 10.2 19.3 6.7 9.7 15.4 16.2 11.7 15.9 8.5 8.8 10.1 14.6 22.1 8.5 13.4 8.7 12.1 10.8 13.2 14.3 11.6 19.9 9.3 11.8 15.4 8.4 14.3 12.8 37.6 9.9 14.2 13.5 16.1 17.2 12.0 8.1 8.1 15.7 20.4 21.5 33.8 29.6 27.5 19.5 37.1 25.8 26.9 37.2 15.2 22.6 19.7 34.7 27.5 18.8 13.1 18.8 36.1 32.5 22.1 21.0 25.2 12.2 11.1 34.8 22.3 25.0 24.9 22.0 24.3 43.5 19.7 38.3 25.6 16.2 30.1 35.3 15.1 25.5 9.2 9.7 16.7 9.9 21.9 29.6 30.4 20.5 10.8 5.0 17.8 26.8 28.7 38.2 22.6 38.5 16.1 35.7 24.9 17.6 23.0 22.5 45.4 39.7 27.9 29.5 30.4 27.3 38.1 14.6 35.7 15.6 18.2 17.9 15.5 12.6 18.2 14.5 17.9 16.0 15.4 7.2 17.6 23.3 13.2 16.0 11.9 7.6 7.7 7.1 7.7 6.7 9.7 8.5 8.8 8.7 8.4 9.9 8.1 22.6 9.6 11.5 9.1 14.9 6.2 5.7 9.5 11.4 10.5 9.2 6.5 26.9 10.0 8.2 11.0 4.2 22.4 8.5 4.8 7.9 12.3 45.3 9.6 13.1 19.8 5.4 24.0 10.4 12.5 16.2 15.0 11.7 8.7 17.2 12.9 10.4 19.8 17.7 10.1 12.9 8.2 6.1 17.7 8.7 14.8 11.1 11.5 14.2 15.0 13.2 25.0 12.3 18.1 11.7 9.1 2.9 9.8 19.2 5.4 12.4 15.4 12.3 15.6 6.6 10.4 14.5 109.6 38.5 11.4 6.8 18.3 11.2 14.1 6.0 3.6 FAM220A "ACPIN1, C7orf70, MGC12966, SIPAR" ENSG00000178397 "Family with sequence similarity 220 member A" Q7Z4H9 7 6329411-6348981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 89.7;testis: 55.9" "Group enriched" "Detected in many" 13 "Early spermatids: 280.0;Late spermatids: 363.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055050 Approved Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA055050: AB_2682684" "unprognostic (3.49e-2)" "unprognostic (3.53e-1)" "unprognostic (2.69e-2)" "unprognostic (9.79e-2)" "unprognostic (3.26e-2)" "unprognostic (4.02e-2)" "prognostic unfavorable (5.17e-6)" "unprognostic (2.78e-1)" "unprognostic (1.43e-2)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (1.51e-2)" "unprognostic (1.30e-1)" "unprognostic (8.84e-3)" "unprognostic (1.14e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (3.71e-2)" 7.1 8.6 13.6 6.9 14.7 2.6 8.3 17.5 17.0 9.1 9.3 6.2 5.4 10.3 7.4 11.5 7.6 7.6 13.8 15.3 13.6 8.2 6.4 6.2 9.9 11.7 12.7 10.7 9.8 19.2 0.6 7.9 12.4 8.0 5.3 11.5 8.4 8.3 89.7 10.1 4.9 9.3 12.5 7.9 6.1 55.9 13.7 12.0 11.7 39.1 10.4 9.6 0.5 13.4 26.9 16.6 11.9 28.0 27.0 22.7 13.1 13.4 16.6 15.9 18.5 10.5 14.6 22.2 15.1 15.9 31.8 19.2 18.2 11.3 20.6 15.5 11.7 7.3 10.0 12.6 29.2 13.5 10.8 12.7 37.5 11.9 28.5 15.3 15.0 16.4 14.6 20.7 13.9 20.9 8.4 24.7 27.8 14.0 21.4 21.6 17.9 18.7 14.7 9.6 12.1 21.0 18.8 23.0 28.6 23.9 22.1 34.9 11.4 12.5 28.5 20.6 17.5 19.7 37.2 23.2 14.6 24.1 39.3 6.6 4.2 8.0 4.7 3.5 4.4 9.1 5.4 6.5 7.7 7.7 8.4 6.8 2.0 12.9 3.8 6.8 6.6 3.7 13.6 14.7 17.5 17.0 15.3 13.6 11.7 12.7 12.4 12.5 13.7 13.4 4.1 3.2 1.1 1.3 8.1 7.8 4.9 6.2 12.0 2.9 6.0 6.9 9.2 0.0 8.2 1.8 6.2 6.3 5.4 3.8 1.9 4.9 280.0 6.0 5.5 4.6 6.1 7.8 4.7 4.8 7.5 6.8 7.7 4.8 1.3 4.4 6.4 3.5 6.2 0.0 4.7 4.2 4.1 6.8 10.5 363.4 8.4 7.4 3.6 2.8 7.1 5.2 6.2 4.0 3.9 4.8 2.1 13.2 3.9 5.5 3.3 2.8 3.4 2.3 0.0 6.3 5.4 23.7 11.4 10.3 10.1 8.2 5.2 3.9 3.4 6.7 FAM3B "2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44" ENSG00000183844 "FAM3 metabolism regulating signaling molecule B" P58499 21 41304212-41357727 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 142.6;pancreas: 212.3;salivary gland: 119.4;stomach 1: 114.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 304.6;Exocrine glandular cells: 399.9;Proximal enterocytes: 831.6" "Cancer enhanced" "Detected in many" "prostate cancer: 40.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Cell line enhanced" "Detected in some" "CACO-2: 19.5;CAPAN-2: 11.7;Hep G2: 32.1;OE19: 27.3;RPMI-8226: 80.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015885, HPA029777, CAB034131" Enhanced Approved Vesicles "Secreted to blood" NA NA 2080000 250000 "Cluster 1: Neutrophils - Mixed function" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB034131: AB_2231472, HPA015885: AB_1848396, HPA029777: AB_2673194" "unprognostic (2.88e-1)" "unprognostic (3.31e-3)" "unprognostic (5.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (6.32e-3)" "unprognostic (1.41e-1)" "unprognostic (8.79e-3)" "unprognostic (9.38e-2)" "unprognostic (1.70e-1)" "unprognostic (4.65e-1)" "unprognostic (3.78e-1)" "unprognostic (5.60e-3)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "unprognostic (1.55e-3)" 1.5 0.1 0.0 2.5 0.1 0.8 17.7 0.1 0.3 4.9 1.3 5.9 142.6 0.3 22.1 56.2 17.2 16.2 0.6 0.1 0.1 17.9 2.6 9.3 1.5 0.1 0.1 0.2 212.3 0.5 5.4 15.2 0.1 37.9 0.1 0.0 119.4 8.7 0.1 2.3 135.0 0.5 0.1 0.6 114.9 6.9 0.1 3.1 8.0 0.0 16.8 34.4 16.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 19.5 11.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.4 0.9 27.3 0.0 0.2 0.0 80.6 0.0 5.8 0.4 0.4 0.0 0.7 0.4 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.3 1.4 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.3 0.7 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.0 22.4 25.7 0.0 0.8 1.3 17.0 2.9 1.2 0.0 101.3 123.1 0.2 102.9 36.5 66.2 0.0 304.6 1.4 2.7 25.4 172.1 25.2 0.2 0.1 2.5 0.0 0.0 0.1 399.9 11.1 3.4 147.3 0.7 1.3 0.6 0.4 0.3 27.0 0.0 0.1 120.9 42.7 5.0 15.8 11.5 0.6 3.9 5.4 1.9 2.1 0.0 0.0 0.0 0.1 144.6 169.0 0.4 0.2 64.9 831.6 0.7 22.4 0.0 0.0 0.4 1.8 28.0 8.1 29.1 1.3 161.3 0.9 0.0 125.2 130.5 FAM43A FLJ90022 ENSG00000185112 "Family with sequence similarity 43 member A" Q8N2R8 3 194685883-194689037 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 54.9" "Cell type enhanced" "Detected in many" "Adipocytes: 89.2;Endothelial cells: 102.4;Extravillous trophoblasts: 83.3;Hepatic stellate cells: 97.1;NK-cells: 75.2;Syncytiotrophoblasts: 162.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 4.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 123.7;NB-4: 72.8;PC-3: 56.9;TIME: 66.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048345 Uncertain Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA048345: AB_2680367" "unprognostic (1.61e-1)" "unprognostic (1.11e-1)" "unprognostic (9.18e-2)" "unprognostic (1.90e-2)" "unprognostic (5.71e-3)" "unprognostic (5.13e-3)" "unprognostic (9.80e-2)" "unprognostic (8.28e-2)" "unprognostic (4.96e-2)" "unprognostic (1.38e-1)" "unprognostic (3.92e-3)" "unprognostic (1.74e-1)" "unprognostic (2.14e-1)" "unprognostic (1.15e-1)" "unprognostic (1.45e-1)" "unprognostic (2.91e-3)" "prognostic unfavorable (9.96e-4)" 25.2 4.8 8.3 5.1 5.6 3.7 15.7 6.9 14.1 16.1 4.0 15.7 1.4 13.0 1.2 15.4 15.1 4.0 30.3 11.7 6.5 41.4 5.8 9.7 10.0 33.2 9.6 4.5 3.0 1.4 8.7 11.2 34.8 22.1 2.3 0.8 8.0 2.7 6.0 25.2 11.6 3.7 7.3 54.9 8.3 4.4 8.3 1.3 8.0 4.0 6.3 17.2 25.1 6.9 0.3 1.8 1.4 1.1 23.3 11.4 10.4 3.8 8.6 0.1 0.0 0.8 0.3 1.3 37.4 11.6 8.5 3.8 2.3 1.0 0.1 0.9 6.4 4.7 10.8 1.3 1.8 1.2 13.5 3.0 4.8 0.5 0.1 0.6 123.7 0.2 2.8 2.5 0.3 1.9 0.0 72.8 6.0 12.8 56.9 6.0 0.4 0.6 0.1 0.2 35.6 3.0 2.4 2.3 7.5 2.4 1.5 15.7 66.3 1.2 1.9 1.6 0.8 0.2 1.5 3.5 0.7 34.3 24.0 2.2 0.6 1.3 0.5 0.5 0.7 1.2 0.3 0.5 0.8 2.5 0.0 0.2 0.9 1.6 0.5 4.5 0.2 0.3 8.3 5.6 6.9 14.1 11.7 6.5 33.2 9.6 34.8 7.3 8.3 6.9 89.2 0.0 2.5 0.0 26.7 4.0 21.4 6.7 4.6 16.0 10.6 7.0 35.1 0.0 4.0 1.8 8.4 21.1 38.3 39.6 7.9 7.8 0.3 3.2 19.5 102.4 6.6 0.4 3.5 1.8 83.3 30.1 8.6 4.0 15.2 3.8 97.1 1.4 6.0 0.0 7.3 8.0 24.4 13.1 3.9 1.3 16.4 9.3 12.4 28.1 7.7 2.2 75.2 0.0 2.6 7.0 19.1 9.8 8.5 20.3 1.0 0.4 1.4 2.8 26.3 5.2 20.8 0.6 14.2 6.5 4.0 162.4 16.0 3.0 11.0 12.6 FAM86B1 MGC16279 ENSG00000186523 "Family with sequence similarity 86 member B1" Q8N7N1 8 12182096-12194133 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 5.4;pituitary gland: 6.4" "Cell type enhanced" "Detected in many" "Granulosa cells: 17.5;Proximal tubular cells: 10.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.5" "HPA041610, HPA055718" Uncertain Uncertain Vesicles NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA041610: AB_2677581, HPA055718: AB_2682895" "unprognostic (1.90e-2)" "unprognostic (8.67e-2)" "unprognostic (2.79e-1)" "unprognostic (3.74e-2)" "unprognostic (3.13e-3)" "unprognostic (1.05e-1)" "unprognostic (1.94e-1)" "unprognostic (1.74e-1)" "unprognostic (5.68e-2)" "unprognostic (1.91e-2)" "unprognostic (1.32e-1)" "unprognostic (6.69e-2)" "unprognostic (8.00e-3)" "unprognostic (2.66e-2)" "unprognostic (1.58e-1)" "unprognostic (7.02e-2)" "unprognostic (2.58e-2)" 0.5 0.7 0.9 0.4 2.2 0.5 1.0 0.2 5.4 2.2 0.0 1.4 0.8 2.3 0.4 0.6 2.4 0.5 0.9 2.6 0.1 1.1 0.3 0.8 0.3 2.0 0.0 3.7 0.9 0.4 6.4 0.1 0.1 2.4 0.0 1.7 0.8 0.3 0.8 1.0 0.6 0.1 0.0 0.6 0.7 0.5 0.5 0.1 1.3 0.0 0.0 1.2 1.5 0.0 0.2 1.2 0.0 2.5 0.0 0.4 1.0 2.0 0.2 0.6 0.3 0.7 0.5 0.5 0.1 0.1 0.7 2.2 0.4 0.7 0.2 0.2 0.3 0.1 0.3 0.3 1.1 0.9 0.9 0.1 0.2 0.2 1.7 0.4 0.1 0.9 0.8 0.7 0.0 1.1 0.0 0.6 0.8 0.7 0.2 0.7 0.5 0.1 0.1 0.6 2.1 0.4 0.2 0.2 0.3 0.2 1.0 0.0 0.0 0.4 0.4 1.8 0.5 0.2 0.6 0.3 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.2 0.2 5.4 2.6 0.1 2.0 0.0 0.1 0.0 0.5 0.0 1.2 3.2 1.8 0.7 0.9 1.1 3.1 1.0 3.4 2.1 4.7 5.0 0.5 8.6 3.0 1.8 2.1 1.5 0.4 0.8 5.9 5.1 5.8 4.7 2.3 1.6 4.2 1.3 0.3 1.8 1.6 2.6 1.5 1.5 1.3 17.5 2.5 1.3 1.9 1.7 0.3 1.5 0.0 1.3 0.6 6.2 1.8 0.7 3.6 0.0 0.1 2.7 4.1 0.0 0.1 3.5 0.3 2.6 0.1 7.0 0.8 10.3 8.5 1.7 0.0 3.3 2.1 0.9 0.8 3.8 1.3 1.1 0.8 2.3 2.4 1.8 FAM86B2 ENSG00000145002 "Family with sequence similarity 86 member B2" P0C5J1 8 12425614-12436343 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 3.2;Early spermatids: 1.6;Granulosa cells: 2.7;Late spermatids: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "hTERT-HME1: 5.3;RPMI-8226: 12.5" "HPA041610, HPA055718" Uncertain Uncertain Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA041610: AB_2677581, HPA055718: AB_2682895" "unprognostic (3.75e-2)" "unprognostic (1.87e-1)" "unprognostic (6.57e-2)" "unprognostic (1.01e-1)" "unprognostic (3.26e-2)" "unprognostic (2.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.48e-1)" "unprognostic (3.82e-1)" "unprognostic (3.24e-1)" "unprognostic (6.04e-4)" "unprognostic (9.37e-2)" "unprognostic (3.78e-2)" "unprognostic (2.31e-2)" "unprognostic (2.62e-1)" "unprognostic (1.37e-1)" "unprognostic (2.13e-2)" 0.3 0.4 0.1 0.1 0.2 0.0 0.4 0.1 0.3 0.6 0.1 0.3 0.1 0.5 0.0 0.9 1.4 0.1 0.1 0.2 0.2 0.5 0.3 0.3 0.0 0.2 0.3 0.6 0.6 0.4 1.0 0.0 0.1 0.4 0.1 0.1 0.3 0.4 0.1 0.3 0.1 0.1 0.0 0.1 0.3 0.2 0.2 0.0 0.9 0.0 0.0 0.4 0.4 0.1 0.2 0.6 0.1 0.0 0.2 1.1 1.3 0.2 0.6 0.4 1.0 0.4 1.1 0.7 0.0 1.2 0.3 0.2 0.9 1.5 0.0 0.0 0.0 0.2 0.9 0.0 1.0 0.0 0.0 0.3 1.3 1.3 5.3 0.0 0.0 0.0 1.1 0.2 0.0 0.3 0.0 0.3 1.0 1.9 0.4 0.1 0.1 12.5 0.0 0.9 1.6 0.0 0.4 1.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.1 0.2 0.1 0.3 0.2 0.2 0.2 0.3 0.1 0.0 0.2 0.1 0.1 3.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.3 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 2.7 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 FAM98A DKFZP564F0522 ENSG00000119812 "Family with sequence similarity 98 member A" Q8NCA5 2 33583660-33599382 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036250, HPA036251" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "HPA036250: AB_2675020, HPA036251: AB_10673124" "unprognostic (7.25e-2)" "unprognostic (9.92e-2)" "unprognostic (1.59e-2)" "unprognostic (1.40e-1)" "unprognostic (1.51e-1)" "unprognostic (2.42e-2)" "prognostic unfavorable (4.86e-7)" "unprognostic (1.07e-1)" "unprognostic (2.29e-1)" "unprognostic (2.78e-2)" "unprognostic (1.01e-1)" "unprognostic (3.51e-1)" "unprognostic (2.02e-2)" "unprognostic (2.38e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (8.18e-5)" "unprognostic (6.01e-2)" 29.2 21.5 21.4 20.5 26.5 7.2 16.3 28.6 30.4 21.7 27.9 20.7 13.6 19.1 19.3 19.9 12.2 15.7 40.6 30.8 25.7 27.4 25.5 11.5 18.4 25.1 24.5 16.5 14.6 51.2 20.5 20.6 29.5 23.0 17.1 17.2 28.0 16.7 61.3 14.9 12.1 36.4 27.7 14.3 19.8 49.4 26.4 17.4 19.2 62.4 22.6 27.5 12.9 39.7 93.4 47.2 25.5 43.9 99.4 108.3 41.9 224.1 81.6 62.3 80.2 49.8 18.8 144.5 41.3 101.8 55.3 41.3 84.8 60.8 84.2 67.7 56.3 119.7 46.9 69.3 47.2 95.5 44.7 56.1 42.2 83.9 52.1 63.5 83.3 15.5 84.4 43.8 108.7 46.1 53.3 28.5 64.4 83.2 59.9 41.1 82.5 51.9 65.0 72.2 45.6 26.1 60.0 89.5 27.0 40.7 36.2 15.6 135.7 39.5 66.1 82.9 89.2 80.2 106.6 142.4 91.2 68.2 56.8 1.3 4.1 2.3 6.4 7.2 6.9 10.7 5.4 5.8 6.1 5.5 6.9 5.7 0.1 4.0 4.6 3.5 9.0 4.1 21.4 26.5 28.6 30.4 30.8 25.7 25.1 24.5 29.5 27.7 26.4 39.7 19.0 22.4 11.5 6.8 17.4 20.4 19.0 12.2 18.8 16.8 15.0 14.0 74.6 11.5 19.8 7.3 2.1 25.5 9.8 6.9 25.4 20.3 14.9 16.7 29.9 21.1 5.4 12.8 22.8 29.2 33.2 31.9 17.9 18.9 2.5 44.4 17.2 23.4 16.4 47.1 15.7 15.1 8.2 7.7 11.8 13.8 22.4 8.7 8.8 6.5 5.9 17.4 16.5 9.0 36.1 26.0 8.7 21.8 40.3 22.6 9.3 46.2 16.5 15.7 0.0 21.7 27.1 41.5 40.1 26.1 20.5 40.0 13.7 54.9 12.1 23.4 FANCD2OS "C3orf24, MGC40179" ENSG00000163705 "FANCD2 opposite strand" Q96PS1 3 10081317-10108255 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 33 "testis: 61.6" "Group enriched" "Detected in some" 59 "Early spermatids: 565.0;Late spermatids: 852.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 1.8" "Immune cell enriched" "Detected in some" 5 "neutrophil: 5.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.4" "Cell line enhanced" "Detected in some" "CACO-2: 1.3;MCF7: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA076166 Approved Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 74: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA076166: " "unprognostic (5.99e-2)" "unprognostic (4.33e-3)" "unprognostic (8.04e-2)" "unprognostic (1.11e-3)" "unprognostic (3.51e-1)" "unprognostic (2.63e-2)" "unprognostic (4.78e-2)" "unprognostic (3.49e-1)" "unprognostic (2.53e-3)" "unprognostic (3.91e-2)" "unprognostic (9.45e-2)" "unprognostic (2.11e-7)" "unprognostic (2.95e-1)" "unprognostic (1.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.80e-1)" 0.0 0.0 0.3 0.0 0.1 1.0 0.0 1.8 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 61.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.4 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.5 0.4 0.3 0.2 0.4 0.3 0.3 0.4 0.2 0.1 0.8 0.3 0.3 5.4 0.2 1.0 0.3 0.1 0.1 0.3 0.1 1.8 0.4 0.2 0.1 0.3 0.2 0.3 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 565.0 0.4 0.0 0.3 0.0 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 852.8 7.2 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.9 0.0 4.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 12.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FCSK "FLJ39408, FUK" ENSG00000157353 "Fucose kinase" Q8N0W3 16 70454595-70480274 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 2.7;Cardiomyocytes: 4.2;Cytotrophoblasts: 5.5;Extravillous trophoblasts: 3.0;Hofbauer cells: 5.0;Syncytiotrophoblasts: 5.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041971 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA041971: AB_10795648" "unprognostic (4.55e-1)" "unprognostic (3.21e-1)" "unprognostic (1.73e-2)" "unprognostic (3.95e-2)" "unprognostic (3.79e-2)" "unprognostic (2.64e-2)" "unprognostic (8.79e-3)" "unprognostic (1.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (4.82e-3)" "unprognostic (4.85e-2)" "prognostic favorable (8.91e-4)" "unprognostic (2.49e-2)" "unprognostic (9.68e-2)" "unprognostic (8.89e-2)" "prognostic favorable (8.38e-4)" 3.9 7.2 5.4 5.4 7.1 5.0 4.9 8.2 7.7 5.6 7.5 7.5 10.1 4.9 2.4 5.6 5.5 3.8 4.3 5.3 5.0 8.9 8.2 4.8 5.4 6.4 4.6 6.6 8.3 9.1 9.8 3.6 5.7 6.3 3.9 2.9 5.9 4.4 5.5 7.2 7.4 3.1 4.5 6.4 6.6 4.5 5.7 3.8 7.9 2.3 2.8 4.8 4.8 11.1 3.4 4.6 2.5 5.8 1.5 1.8 10.0 1.8 2.8 2.2 3.0 4.2 10.0 2.3 8.8 1.7 0.7 4.8 1.8 4.7 1.6 4.4 6.5 2.9 8.9 4.5 3.7 3.8 2.3 3.0 5.4 2.1 4.4 3.3 4.3 4.6 5.9 2.6 1.8 10.3 4.6 9.2 1.6 5.5 2.7 7.0 0.6 10.4 5.9 5.5 4.0 5.3 10.1 3.7 5.3 1.9 14.8 7.5 5.0 1.8 2.4 4.0 2.2 9.5 5.1 4.8 3.3 3.8 4.2 0.2 1.9 0.8 1.9 1.0 1.6 0.8 1.9 1.9 1.1 1.5 2.6 1.2 1.6 1.2 1.2 1.3 1.4 1.2 5.4 7.1 8.2 7.7 5.3 5.0 6.4 4.6 5.7 4.5 5.7 11.1 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 5.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 3.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 5.2 0.2 0.0 0.0 0.0 FERMT3 "KIND3, MGC10966, MIG-2, MIG2B, UNC112C, URP2" ENSG00000149781 "Fermitin family member 3" Q86UX7 11 64206678-64223891 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.6;lymphoid tissue: 130.1" "Cell type enhanced" "Detected in many" "dendritic cells: 118.3;granulocytes: 96.4;Hofbauer cells: 193.1;Kupffer cells: 95.8;Langerhans cells: 88.0;Macrophages: 232.9;monocytes: 142.9;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 306.9;HL-60: 135.9;HMC-1: 314.2;Karpas-707: 127.6;MOLT-4: 121.8;NB-4: 174.1;U-937: 138.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065231 Approved Vesicles NA NA 160000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA065231: AB_2685439" "unprognostic (1.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.38e-3)" "prognostic favorable (9.89e-4)" "unprognostic (8.77e-2)" "unprognostic (1.83e-2)" "unprognostic (3.56e-2)" "unprognostic (2.46e-1)" "unprognostic (4.20e-1)" "unprognostic (3.98e-1)" "unprognostic (2.70e-1)" "unprognostic (3.88e-1)" "prognostic unfavorable (2.12e-5)" "unprognostic (3.08e-3)" "unprognostic (5.25e-2)" "unprognostic (4.97e-2)" "unprognostic (1.75e-1)" 25.1 14.5 9.4 63.3 11.6 180.6 13.0 11.2 18.1 8.5 12.2 17.3 22.0 8.4 0.7 6.4 13.6 15.6 12.0 9.8 11.6 11.1 12.5 46.2 89.2 17.9 12.2 5.1 7.0 1.3 5.9 15.0 13.2 8.2 8.1 0.6 10.7 4.4 6.0 7.1 34.1 9.4 13.3 130.1 29.6 4.5 17.1 48.7 10.0 4.6 41.8 19.8 7.3 15.3 1.2 1.6 0.5 0.9 0.3 0.8 2.0 1.4 0.2 0.4 0.3 2.6 2.3 32.6 3.2 6.3 0.7 2.4 1.0 0.5 0.5 83.9 0.6 306.9 1.6 0.1 10.8 135.9 314.2 1.2 1.1 5.2 0.0 0.5 81.2 77.0 7.3 127.6 8.6 3.5 121.8 174.1 1.2 1.0 2.3 72.4 8.8 0.7 0.3 0.7 1.9 0.5 0.7 4.5 1.7 0.7 2.0 92.6 7.8 1.1 2.5 1.9 0.9 1.5 3.3 59.4 19.5 138.9 86.6 204.1 207.0 236.5 120.0 192.6 114.9 54.5 94.1 112.0 162.0 53.1 60.9 80.6 184.6 102.4 151.2 195.7 120.9 292.6 9.4 11.6 11.2 18.1 9.8 11.6 17.9 12.2 13.2 13.3 17.1 15.3 3.8 9.6 14.7 0.7 52.1 4.7 0.9 0.3 3.4 0.5 3.3 5.2 2.4 4.3 3.9 0.0 0.0 1.2 118.3 6.1 0.0 0.8 0.4 4.3 5.6 7.9 0.0 62.5 1.2 2.4 1.4 5.4 19.9 7.3 96.4 0.4 19.6 1.4 193.1 0.0 1.5 32.1 0.0 95.8 88.0 0.9 0.9 232.9 17.8 5.6 142.9 0.3 93.7 1.0 1.5 4.3 10.9 2.6 35.2 0.9 8.2 0.4 1.0 0.3 6.6 13.7 6.6 1.2 0.8 1.9 4.5 2.6 78.5 1.4 15.0 0.7 FETUB ENSG00000090512 "Fetuin B" Q9UGM5 3 186635969-186653141 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "liver: 234.6" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 47.2" "Cancer enriched" "Detected in some" 12 "liver cancer: 44.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035132, HPA035133" Supported Approved Vesicles "Secreted to blood" NA NA 47500000000 3600000000 "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA035132: AB_10601650, HPA035133: " "unprognostic (9.01e-2)" "unprognostic (1.95e-1)" "unprognostic (4.62e-1)" "unprognostic (8.74e-2)" "unprognostic (6.28e-3)" "unprognostic (1.24e-2)" "unprognostic (7.55e-2)" "unprognostic (9.78e-2)" "unprognostic (1.73e-2)" "unprognostic (9.18e-2)" "unprognostic (1.79e-1)" "unprognostic (8.39e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 1.6 0.0 0.1 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.1 0.0 0.4 234.6 0.0 0.0 0.1 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 5.8 0.0 2.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 3.9 0.0 5.3 0.2 0.2 0.1 0.0 2.7 0.2 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.7 47.2 0.0 0.0 0.0 0.2 0.0 2.9 0.0 5.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 FGD6 "FLJ11183, ZFYVE24" ENSG00000180263 "FYVE, RhoGEF and PH domain containing 6" Q6ZV73 12 95076749-95217482 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 109.0;Microglial cells: 90.9;Pancreatic endocrine cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007974 Approved Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA007974: AB_1848520" "unprognostic (1.28e-2)" "unprognostic (2.67e-3)" "unprognostic (6.06e-2)" "unprognostic (5.56e-2)" "unprognostic (1.65e-1)" "unprognostic (4.70e-2)" "unprognostic (4.66e-2)" "unprognostic (1.35e-3)" "unprognostic (1.32e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.62e-5)" "prognostic unfavorable (9.83e-4)" "prognostic unfavorable (5.46e-6)" "unprognostic (1.01e-2)" "unprognostic (1.38e-1)" "unprognostic (3.33e-2)" "unprognostic (1.92e-1)" 1.8 3.3 3.3 5.1 5.3 1.5 2.9 0.3 5.2 3.3 4.0 4.5 1.3 3.4 1.2 3.3 1.9 4.9 3.6 3.2 0.4 3.3 3.1 5.2 5.5 2.0 1.7 4.5 3.4 1.2 1.1 4.3 0.3 3.3 4.2 2.2 2.2 4.0 1.6 7.8 3.5 3.5 1.8 3.3 1.8 3.0 2.9 2.5 5.2 1.3 9.7 3.3 3.5 1.6 22.5 20.1 18.2 2.0 1.9 1.8 9.5 3.1 4.4 1.1 1.8 7.7 15.0 23.8 5.1 2.0 1.3 8.9 3.3 18.7 2.6 2.5 2.0 1.1 3.2 3.8 2.5 2.5 0.2 7.5 8.4 2.2 22.1 7.3 11.9 3.2 5.1 0.4 0.6 1.2 2.0 0.5 7.5 2.8 6.9 5.5 3.6 1.9 12.8 7.1 3.0 4.9 9.0 4.6 0.4 9.1 2.1 0.2 16.4 0.7 2.0 0.9 2.4 2.2 5.3 6.7 0.9 1.6 1.4 0.2 1.6 0.0 0.0 2.5 0.0 0.5 0.0 0.0 0.9 1.4 0.1 0.0 0.1 0.1 2.0 0.0 0.0 0.6 3.3 5.3 0.3 5.2 3.2 0.4 2.0 1.7 0.3 1.8 2.9 1.6 12.4 16.0 17.0 109.0 3.9 48.6 21.9 18.6 29.0 3.8 11.0 10.5 22.2 10.0 14.0 9.2 4.2 4.5 1.5 26.5 0.0 22.6 1.7 10.9 17.3 22.3 12.5 1.7 23.9 21.9 8.8 7.3 6.6 22.1 1.3 10.6 16.4 5.2 11.7 1.7 22.4 15.5 10.2 16.1 11.8 3.1 12.5 11.0 1.8 90.9 12.6 1.9 1.0 4.0 4.1 78.1 17.0 10.5 3.5 19.3 14.9 5.2 12.0 9.7 0.0 3.5 6.1 4.8 16.0 28.3 24.9 43.8 1.7 4.9 5.5 30.7 FGFRL1 ENSG00000127418 "Fibroblast growth factor receptor like 1" Q8N441 4 1009936-1026898 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 34.0;Granulosa cells: 30.9;Hepatocytes: 37.5;Muller glia cells: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.1;non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-251 MG: 99.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026019, HPA068828" Approved Supported Vesicles No No "Cluster 7: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Vesicles "CAB026019: , HPA068828: AB_2686043" "unprognostic (1.30e-2)" "unprognostic (2.54e-2)" "unprognostic (6.27e-2)" "unprognostic (2.80e-2)" "unprognostic (1.23e-2)" "unprognostic (1.48e-1)" "unprognostic (2.62e-2)" "unprognostic (9.79e-2)" "unprognostic (4.87e-3)" "unprognostic (8.46e-2)" "unprognostic (2.01e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-3)" "unprognostic (1.49e-1)" "unprognostic (7.80e-2)" "unprognostic (1.06e-2)" "unprognostic (1.96e-2)" 38.1 56.0 40.8 5.0 43.3 7.6 24.1 40.6 49.5 15.7 29.8 10.2 7.3 9.9 3.4 5.5 36.0 9.3 19.8 39.2 33.5 25.4 52.8 15.1 3.1 49.9 45.8 25.4 71.6 16.1 21.6 3.0 46.5 12.4 4.9 10.5 37.6 2.7 20.6 10.7 13.5 4.0 42.2 9.1 27.2 5.5 47.9 1.4 67.1 9.6 2.2 11.2 8.0 42.1 23.2 31.6 11.3 34.3 11.9 12.3 2.9 40.4 6.2 12.9 8.4 23.1 47.9 2.6 49.3 63.3 58.3 5.8 21.8 14.1 11.8 8.3 21.0 0.3 41.2 61.5 24.0 13.7 5.6 25.7 11.7 22.4 9.5 48.4 12.5 9.3 25.3 8.9 7.9 30.8 16.0 37.7 14.2 39.7 83.8 24.7 16.3 16.7 22.6 3.6 1.2 2.2 38.1 0.8 15.2 13.4 22.5 11.9 26.1 68.8 27.2 35.2 99.8 8.9 12.9 3.8 18.1 15.6 22.8 0.6 0.0 0.0 0.2 1.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.1 40.8 43.3 40.6 49.5 39.2 33.5 49.9 45.8 46.5 42.2 47.9 42.1 3.8 3.2 4.1 34.0 2.8 6.5 3.7 5.4 2.2 5.4 13.2 6.1 8.5 11.5 6.9 7.3 0.0 1.6 4.1 4.4 0.0 9.6 0.2 6.0 4.2 2.6 1.8 4.8 3.2 10.2 26.6 5.1 6.6 13.5 1.3 30.9 5.3 37.5 3.2 0.0 2.8 11.0 0.0 1.6 2.5 1.2 4.4 3.4 7.2 1.9 1.3 94.0 1.0 5.0 5.4 19.9 2.7 3.4 2.2 11.4 2.9 7.6 7.0 5.6 0.0 3.3 5.1 0.4 4.2 1.2 4.7 1.5 4.2 17.5 3.6 8.8 FJX1 "FLJ22416, FLJ25593" ENSG00000179431 "Four-jointed box kinase 1" Q86VR8 11 35618460-35620865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 29.0;Cytotrophoblasts: 25.6;Endometrial ciliated cells: 30.6;Endometrial stromal cells: 35.4;Granulosa cells: 31.2" "Cancer enhanced" "Detected in all" "glioma: 34.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-251 MG: 60.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059220 Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA059220: AB_2683950" "unprognostic (8.99e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-3)" "unprognostic (5.20e-2)" "unprognostic (5.72e-2)" "unprognostic (9.56e-3)" "unprognostic (5.16e-2)" "unprognostic (1.06e-2)" "unprognostic (1.74e-1)" "unprognostic (4.39e-3)" "unprognostic (5.28e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (9.24e-9)" "unprognostic (1.64e-2)" "unprognostic (9.64e-2)" "unprognostic (8.35e-2)" "prognostic unfavorable (6.56e-4)" 8.9 5.9 8.4 1.7 10.4 0.1 3.5 6.8 9.2 7.8 4.4 2.1 0.3 5.2 1.5 3.8 4.9 2.3 2.5 10.2 7.1 9.5 2.2 2.8 1.1 8.2 13.1 9.2 3.5 0.6 2.3 3.4 6.6 5.2 0.2 0.7 2.5 2.2 1.1 6.0 1.3 1.6 9.6 5.0 1.6 0.7 12.0 1.0 2.9 0.3 1.7 3.8 3.3 10.1 23.3 11.4 12.0 3.8 4.1 12.6 3.7 25.4 17.3 24.1 17.2 14.5 7.1 0.0 5.7 10.2 49.6 24.3 4.2 42.6 20.4 0.3 33.0 2.1 4.4 0.6 9.7 2.7 0.1 4.8 31.8 12.7 38.1 3.9 11.1 1.2 12.5 0.1 23.6 5.4 0.8 0.0 16.4 0.1 33.6 1.4 26.6 5.4 18.6 28.5 11.2 6.4 2.7 2.1 7.5 8.7 48.2 0.5 21.7 19.0 35.5 3.7 60.9 0.0 0.0 0.0 33.9 1.1 28.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 10.4 6.8 9.2 10.2 7.1 8.2 13.1 6.6 9.6 12.0 10.1 7.8 0.0 0.0 9.4 0.2 17.5 15.8 14.0 29.0 1.8 5.3 13.3 1.2 0.0 3.9 0.0 12.5 25.6 0.0 0.1 1.9 7.6 0.3 30.6 35.4 11.8 0.0 0.0 6.6 0.2 13.9 7.2 0.0 6.5 0.0 31.2 17.9 0.4 3.6 0.0 3.9 0.0 2.0 0.6 1.7 0.1 0.6 1.1 0.0 1.0 0.0 12.5 0.0 6.6 1.7 1.4 0.0 0.7 0.0 22.9 0.0 8.0 4.3 0.5 0.0 6.0 22.3 0.6 1.0 5.6 9.5 11.9 0.4 3.1 0.0 2.5 FKBP1B "FKBP12.6, FKBP1L, FKBP9, OTK4, PPIase" ENSG00000119782 "FKBP prolyl isomerase 1B" P68106 2 24049701-24063681 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.9" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.2;T-reg: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 47.9;NTERA-2: 42.9;SH-SY5Y: 30.7;SuSa: 46.1;TIME: 38.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045572, HPA051798" Uncertain Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "HPA045572: AB_2732521, HPA051798: AB_2681615" "unprognostic (3.01e-3)" "unprognostic (3.35e-1)" "unprognostic (7.05e-2)" "unprognostic (9.89e-3)" "unprognostic (1.47e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-2)" "unprognostic (9.19e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-1)" "unprognostic (9.55e-2)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (3.43e-2)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" 5.6 4.4 32.5 2.2 36.1 1.6 5.5 26.5 47.9 6.7 23.0 7.1 19.6 4.8 2.7 8.3 3.9 5.4 5.1 39.2 30.9 8.7 6.6 10.5 1.5 27.7 27.6 5.5 7.5 7.0 6.4 4.0 30.3 7.2 3.3 7.7 6.6 6.3 1.4 6.5 6.8 2.7 25.9 2.8 15.0 1.6 32.7 1.6 6.7 1.2 2.3 5.6 8.1 30.5 0.2 2.0 17.2 0.0 10.9 4.7 6.2 5.8 6.0 2.5 3.6 1.2 2.0 0.0 4.3 10.3 15.4 6.8 25.7 20.2 1.6 3.0 16.1 6.0 0.2 47.9 4.5 0.0 14.1 3.9 4.6 5.9 1.1 14.7 16.5 6.8 1.5 0.1 5.9 0.2 2.0 0.0 42.9 1.7 3.0 3.1 1.5 0.2 2.0 1.3 4.1 30.7 0.3 0.1 5.8 46.1 1.2 2.2 38.0 0.0 5.2 0.2 1.4 1.1 0.5 0.0 6.4 0.0 1.3 0.4 0.4 2.2 0.1 0.4 0.0 0.1 0.2 0.2 1.0 1.2 0.0 0.1 0.0 0.1 0.0 0.2 2.8 0.5 32.5 36.1 26.5 47.9 39.2 30.9 27.7 27.6 30.3 25.9 32.7 30.5 9.3 0.0 6.8 2.9 1.8 9.2 14.0 13.7 11.4 2.1 6.5 13.7 0.9 22.8 4.7 7.3 0.0 4.9 2.7 15.8 13.7 27.6 0.6 3.5 5.0 10.9 9.5 7.0 16.9 38.2 31.9 6.9 16.3 7.1 1.3 3.4 15.7 10.2 7.5 1.7 7.8 8.9 2.0 4.0 17.4 2.9 2.8 9.1 28.4 4.7 13.0 31.4 1.0 2.5 1.3 49.8 25.4 4.1 2.4 15.5 10.6 6.8 2.0 3.6 26.3 2.9 10.6 1.6 5.4 9.1 7.4 5.2 4.9 1.4 4.5 19.3 FO393400.1 ENSG00000285382 "Novel protein" 20 32632183-32743567 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 1.8;choroid plexus: 1.0;retina: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "HEL: 4.6" HPA054119 Approved Vesicles NA NA "Cluster 36: HEL - Hemostasis" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA054119: AB_2682388" 0.0 0.0 1.4 0.0 1.4 0.0 0.1 1.5 1.8 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 1.5 0.1 0.3 0.0 0.0 1.4 1.4 0.0 0.1 0.0 0.0 1.5 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.4 1.5 1.8 1.3 1.5 1.4 1.4 1.5 1.3 1.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FPGT GFPP ENSG00000254685 "Fucose-1-phosphate guanylyltransferase" O14772 1 74198212-74234086 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072331 Uncertain Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA072331: " "unprognostic (1.53e-1)" "unprognostic (1.94e-1)" "unprognostic (8.18e-3)" "unprognostic (4.32e-2)" "unprognostic (5.14e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.86e-1)" "unprognostic (5.14e-2)" "unprognostic (2.58e-1)" "unprognostic (7.59e-2)" "unprognostic (1.33e-1)" "unprognostic (3.59e-3)" "unprognostic (1.44e-1)" "unprognostic (7.88e-2)" "unprognostic (3.53e-2)" "unprognostic (1.91e-1)" 10.5 10.5 3.7 9.9 5.6 4.2 12.9 5.4 4.9 8.9 6.2 12.0 11.7 8.7 10.6 10.7 9.2 13.2 8.7 4.0 5.0 15.4 14.1 8.9 9.0 5.8 5.4 13.3 10.4 13.5 5.3 10.8 6.2 9.9 11.1 6.8 10.6 8.5 4.9 12.0 12.3 8.8 5.3 10.1 12.6 8.1 5.0 8.5 19.5 5.6 9.8 8.3 6.0 8.3 12.4 10.1 7.5 11.0 17.0 15.8 11.2 16.0 10.6 10.8 12.7 5.7 9.1 7.6 19.2 9.5 12.2 10.3 13.6 14.6 17.1 15.4 5.8 17.3 11.1 9.7 14.1 13.2 12.7 13.1 18.6 10.8 5.1 7.4 11.3 10.5 18.2 8.8 17.1 3.3 7.4 2.7 8.2 15.9 9.1 7.8 17.5 10.8 9.5 8.9 7.8 7.8 11.8 17.1 18.6 2.4 20.6 14.9 10.3 4.7 8.8 25.8 12.2 9.6 7.3 10.2 19.0 12.8 16.2 19.5 20.1 21.7 5.5 20.5 6.5 5.0 5.5 5.2 12.6 6.1 6.2 5.6 6.1 5.8 18.4 1.2 7.6 10.7 3.7 5.6 5.4 4.9 4.0 5.0 5.8 5.4 6.2 5.3 5.0 8.3 7.1 6.4 3.2 0.0 3.0 6.8 4.9 13.3 4.6 7.1 7.6 5.6 10.2 14.3 9.3 11.0 2.1 12.7 2.5 7.8 19.6 5.3 8.9 6.0 4.8 4.9 6.0 9.5 0.0 7.1 11.0 7.0 4.1 4.2 5.1 4.9 6.4 9.8 15.1 3.3 0.0 7.3 6.1 9.4 4.6 7.3 10.2 10.3 5.4 0.0 9.0 10.6 8.2 0.0 0.0 6.5 8.9 5.7 1.2 2.5 11.0 15.3 12.7 5.5 26.3 5.8 7.2 9.7 10.4 5.7 6.5 6.2 5.2 4.9 7.3 3.0 FPGT-TNNI3K ENSG00000259030 "FPGT-TNNI3K readthrough" 1 74198235-74544393 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 8.7" "Cell type enhanced" "Detected in many" "Astrocytes: 13.1;Cardiomyocytes: 10.2;Cone photoreceptor cells: 10.4;Excitatory neurons: 10.3;Inhibitory neurons: 11.2;Oligodendrocyte precursor cells: 17.1;Oligodendrocytes: 26.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.3;CAPAN-2: 2.2;SiHa: 3.1" HPA072331 Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA072331: " "unprognostic (6.29e-2)" "unprognostic (4.96e-2)" "unprognostic (1.99e-1)" "unprognostic (1.46e-1)" "unprognostic (1.24e-1)" "unprognostic (3.44e-3)" "unprognostic (8.37e-2)" "unprognostic (1.70e-2)" "unprognostic (6.63e-2)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (8.37e-2)" "unprognostic (6.76e-3)" "unprognostic (3.20e-2)" "unprognostic (2.75e-1)" "unprognostic (1.11e-2)" "unprognostic (7.87e-3)" 2.4 1.2 0.8 0.5 1.3 0.4 1.4 2.9 1.9 1.1 0.0 1.8 0.3 1.4 0.8 1.4 1.3 0.8 8.7 1.0 1.2 1.6 0.4 1.4 0.6 1.0 1.0 1.3 0.5 1.0 1.4 0.5 1.4 1.2 0.7 3.4 0.9 1.3 3.5 2.1 0.8 1.5 1.1 1.5 1.0 0.8 0.9 0.2 1.1 1.8 0.6 1.3 1.1 2.4 0.0 0.5 0.3 0.7 0.4 2.3 0.0 1.0 0.5 0.1 0.1 0.5 2.2 0.0 1.5 0.1 0.0 0.0 0.1 1.5 0.2 0.0 0.0 0.8 0.0 0.0 0.3 0.2 0.1 0.9 0.9 0.0 0.1 0.3 0.1 0.1 0.0 0.8 0.5 0.0 0.0 0.1 0.0 0.8 0.4 1.1 1.8 0.0 0.2 0.0 0.5 1.5 3.1 0.1 0.1 0.0 0.0 1.0 0.1 0.3 0.1 0.1 0.4 0.1 0.0 0.9 0.4 0.5 0.4 1.3 1.6 1.4 0.4 1.9 1.2 0.9 1.4 0.8 0.9 0.9 1.8 0.9 1.8 0.4 0.5 0.8 1.6 1.6 0.8 1.3 2.9 1.9 1.0 1.2 1.0 1.0 1.4 1.1 0.9 2.4 0.5 3.2 1.1 13.1 0.9 0.1 0.5 0.2 0.0 4.9 0.6 0.9 10.2 1.5 0.7 0.0 10.4 0.2 0.2 0.5 0.0 0.2 1.4 0.6 0.3 0.9 3.0 0.0 10.3 1.0 0.2 1.3 0.0 0.2 2.5 1.6 1.8 0.5 0.2 5.0 11.2 0.2 0.0 0.9 0.3 0.6 2.8 0.7 1.8 7.5 0.1 1.1 0.0 17.1 26.7 1.3 1.6 0.7 0.3 0.3 0.0 1.4 1.6 2.7 0.0 1.5 1.1 2.1 1.7 0.1 0.1 0.0 0.4 0.8 0.5 0.2 FST FS ENSG00000134363 Follistatin P19883 5 53480626-53487134 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 68.7" "Cell type enriched" "Detected in many" 6 "Granulosa cells: 700.1" "Cancer enhanced" "Detected in all" "liver cancer: 45.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 351.1;HaCaT: 292.3;HBEC3-KT: 191.3;HMC-1: 206.5;PC-3: 558.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA016612, CAB026025" Approved Approved Vesicles "Secreted to blood" NA NA 1800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "CAB026025: , HPA016612: " "unprognostic (1.43e-1)" "unprognostic (6.50e-2)" "unprognostic (1.44e-1)" "unprognostic (7.73e-3)" "unprognostic (2.30e-1)" "unprognostic (1.50e-3)" "unprognostic (8.02e-2)" "unprognostic (2.32e-2)" "unprognostic (3.06e-1)" "unprognostic (1.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (4.44e-5)" "unprognostic (1.21e-3)" "unprognostic (2.48e-1)" "unprognostic (2.07e-2)" "unprognostic (2.18e-1)" 26.1 6.2 0.8 3.0 0.5 0.4 15.2 0.4 0.7 7.7 0.7 9.8 1.8 4.2 3.7 6.5 11.8 7.2 9.4 2.0 2.0 2.9 68.7 8.2 1.6 1.8 1.0 9.9 2.6 0.5 5.9 24.1 0.9 15.5 3.0 0.3 11.3 10.8 9.2 18.0 8.8 4.7 0.5 0.3 11.1 5.0 1.1 2.3 4.0 7.7 12.9 40.4 7.5 0.7 20.0 1.8 33.7 0.0 38.6 13.5 55.4 76.3 351.1 46.4 45.4 0.3 0.2 0.0 0.6 19.9 2.3 292.3 0.0 191.3 32.7 0.8 0.2 4.0 1.7 31.3 20.4 0.3 206.5 31.0 0.5 84.5 55.0 31.3 40.0 0.0 0.0 0.6 29.7 0.1 0.1 1.6 52.1 0.0 558.2 4.2 43.6 0.0 0.0 31.9 0.5 0.1 3.1 0.2 2.0 83.9 0.3 0.3 0.2 124.1 35.3 13.2 11.1 0.4 0.1 0.1 14.8 4.1 116.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.5 0.4 0.7 2.0 2.0 1.8 1.0 0.9 0.5 1.1 0.7 5.2 0.0 1.1 0.0 1.0 20.0 31.5 64.4 13.1 0.0 0.9 23.4 11.4 0.0 8.3 0.0 0.0 0.6 0.0 0.0 0.0 1.6 0.4 0.1 3.4 2.9 0.0 0.0 0.1 4.6 14.8 107.7 3.6 0.1 0.0 700.1 1.1 57.2 1.8 0.0 0.7 0.0 2.0 0.8 16.4 1.5 3.1 1.5 5.4 0.0 0.0 0.0 0.0 0.0 0.0 16.6 0.0 11.3 0.2 37.1 0.0 0.1 1.6 0.0 13.1 29.6 33.3 0.3 12.2 4.0 4.7 6.0 2.0 0.3 0.0 51.8 FTCDNL1 FONG ENSG00000226124 "Formiminotransferase cyclodeaminase N-terminal like" E5RQL4 2 199760544-199851192 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 39.8;Excitatory neurons: 43.5;Oligodendrocytes: 115.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA065748 Approved Vesicles "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA065748: " "unprognostic (1.78e-1)" "unprognostic (1.70e-1)" "unprognostic (1.27e-2)" "unprognostic (9.80e-2)" "unprognostic (3.09e-1)" "unprognostic (7.21e-2)" "unprognostic (1.54e-3)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (5.37e-2)" "unprognostic (9.86e-2)" "prognostic favorable (3.31e-4)" "unprognostic (3.92e-2)" "unprognostic (4.63e-2)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.21e-2)" 2.4 4.9 4.4 0.9 7.9 2.3 2.1 5.4 5.5 0.6 1.8 1.1 1.0 0.4 1.8 1.3 1.9 0.9 2.9 4.5 4.8 4.2 10.0 1.4 2.0 6.1 6.7 1.0 2.2 1.5 0.9 0.6 5.7 1.2 1.1 1.4 2.4 0.6 8.1 1.2 0.8 1.1 6.1 4.6 0.9 1.0 6.0 0.7 5.7 8.4 0.8 0.7 0.9 7.6 0.6 1.9 0.1 0.0 1.9 1.1 1.4 0.7 0.7 1.0 0.4 0.0 3.5 2.0 0.2 0.8 5.7 0.0 0.9 5.3 1.2 2.3 0.5 1.5 0.8 1.7 0.7 5.5 6.5 0.8 0.2 0.4 0.1 0.7 0.0 4.9 2.7 0.1 0.7 6.0 1.9 2.1 1.6 0.5 4.0 0.3 0.2 0.0 0.4 0.0 2.3 0.0 3.4 3.2 3.2 1.3 4.8 7.1 0.6 2.7 0.0 1.8 1.1 4.7 2.9 1.1 5.2 2.7 1.3 0.0 4.1 1.7 0.4 5.5 1.7 3.4 1.7 0.6 5.8 2.1 1.1 1.8 0.0 1.1 5.1 8.7 0.0 1.4 4.4 7.9 5.4 5.5 4.5 4.8 6.1 6.7 5.7 6.1 6.0 7.6 0.8 0.0 0.0 39.8 3.2 2.7 2.9 0.0 13.6 3.3 6.2 5.5 5.7 4.3 1.3 3.7 4.2 1.5 3.3 0.3 1.9 0.2 2.4 8.4 0.8 1.5 0.0 5.9 43.5 0.7 1.4 1.4 4.6 3.3 0.0 5.9 2.2 6.9 7.4 1.7 23.5 1.2 0.0 8.1 4.7 1.0 0.3 8.2 7.2 17.8 2.1 1.7 0.0 24.6 115.4 0.3 0.1 0.4 1.4 2.6 1.0 10.6 0.0 6.5 0.0 2.4 3.4 0.4 2.0 6.9 2.3 0.3 1.5 10.3 1.1 1.2 FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 181.7;Distal enterocytes: 226.6;Paneth cells: 221.0;Proximal enterocytes: 210.9;Syncytiotrophoblasts: 200.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 165.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 60000000 "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA046542: AB_2679691, HPA056371: AB_2683108" "unprognostic (6.94e-3)" "unprognostic (6.53e-2)" "unprognostic (2.68e-3)" "prognostic favorable (2.45e-4)" "unprognostic (5.64e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (4.99e-1)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (4.23e-2)" "prognostic favorable (5.70e-13)" "unprognostic (3.75e-2)" "unprognostic (4.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.13e-3)" 34.2 34.4 8.3 49.8 8.2 7.7 26.3 8.3 11.2 54.5 23.8 124.2 90.3 20.7 113.0 17.0 51.1 46.6 20.6 8.3 10.5 78.2 104.8 55.1 168.2 9.5 8.8 23.8 23.9 56.9 17.6 72.6 9.6 50.2 140.7 5.7 40.8 60.4 15.8 14.9 81.3 26.7 9.3 71.8 63.9 27.7 10.8 26.8 70.6 17.7 94.1 74.9 13.2 12.8 15.9 10.6 2.2 31.9 4.2 0.3 11.0 16.6 34.4 17.1 31.6 14.5 165.1 23.9 40.9 21.3 18.8 9.4 15.3 35.4 22.4 16.9 25.6 19.7 9.2 32.7 14.2 2.0 62.7 15.3 19.7 6.2 8.1 55.2 6.9 13.3 9.3 0.5 20.6 17.5 5.0 17.7 5.4 48.1 16.9 26.9 0.2 26.2 63.5 40.5 10.9 10.6 47.9 18.5 26.2 17.9 13.6 7.8 1.8 5.8 9.0 38.9 5.6 28.5 31.0 8.5 14.5 58.9 9.5 54.8 100.4 51.9 27.2 99.9 23.1 23.8 19.5 22.9 44.0 14.1 18.9 22.0 12.8 44.6 91.1 25.4 21.4 64.8 8.3 8.2 8.3 11.2 8.3 10.5 9.5 8.8 9.6 9.3 10.8 12.8 12.9 25.6 28.6 4.2 10.5 3.6 27.4 99.3 6.8 4.4 22.2 10.4 5.6 40.0 77.8 84.6 0.0 181.7 13.9 226.6 15.6 64.1 61.0 31.5 2.8 11.6 10.8 20.6 5.8 50.3 24.2 16.7 33.1 13.3 8.2 11.1 25.7 42.7 156.4 0.0 6.3 44.4 44.7 121.0 13.5 24.4 23.3 85.4 8.8 2.8 29.6 13.0 10.3 4.0 4.7 34.9 221.0 19.5 8.7 23.6 210.9 40.2 53.7 5.0 6.6 16.7 13.2 109.0 24.8 8.5 2.8 200.6 11.2 34.6 79.5 40.3 FUT4 "CD15, ELFT, FCT3A, FUC-TIV" ENSG00000196371 "Fucosyltransferase 4" P22083 11 94543840-94549898 "Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 100.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 22.8;Ductal cells: 19.3;Gastric mucus-secreting cells: 21.9;Intestinal goblet cells: 23.7;Pancreatic endocrine cells: 22.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 11.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HL-60: 37.4;NB-4: 24.2;THP-1: 46.6;U-937: 32.9" "Low region specificity" "Detected in single" "CAB000014, CAB016129" Enhanced Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "CAB000014: , CAB016129: AB_626918" "unprognostic (6.36e-2)" "unprognostic (7.53e-2)" "unprognostic (4.70e-3)" "unprognostic (2.46e-3)" "unprognostic (1.46e-2)" "unprognostic (2.29e-2)" "unprognostic (1.66e-2)" "prognostic unfavorable (3.64e-4)" "unprognostic (7.26e-2)" "unprognostic (4.14e-1)" "unprognostic (4.81e-3)" "unprognostic (1.27e-1)" "unprognostic (9.08e-3)" "unprognostic (8.17e-2)" "unprognostic (1.37e-1)" "unprognostic (4.04e-1)" "unprognostic (3.10e-3)" 3.7 1.2 1.3 4.7 1.1 100.8 2.5 1.2 1.4 2.3 0.2 9.2 12.3 2.8 1.2 1.8 2.1 3.7 1.7 1.6 1.1 1.9 1.5 2.1 3.7 1.3 1.0 2.9 6.7 0.5 1.3 3.1 1.3 1.6 8.7 1.6 6.8 2.2 0.9 0.8 10.8 2.5 1.6 3.6 10.8 1.3 1.4 3.7 1.2 1.1 2.8 2.1 1.3 1.9 2.9 1.4 1.7 0.0 5.3 4.8 8.9 2.6 1.3 2.3 2.5 12.5 4.0 0.0 6.1 4.4 1.2 1.4 2.9 0.3 2.1 19.1 2.9 9.4 2.2 0.3 2.7 37.4 8.0 4.1 0.1 2.9 0.0 0.5 3.6 8.3 9.7 0.0 2.7 1.4 7.9 24.2 3.4 11.6 3.4 6.9 0.0 0.0 2.4 1.9 2.4 0.9 1.5 3.7 1.5 5.1 2.1 46.6 3.3 1.8 4.9 0.0 1.0 1.1 0.6 0.0 1.6 32.9 1.1 0.5 0.8 0.7 0.2 0.4 0.1 0.1 0.2 0.3 0.4 0.1 0.2 0.1 0.3 0.2 1.2 0.5 0.5 0.2 1.3 1.1 1.2 1.4 1.6 1.1 1.3 1.0 1.3 1.6 1.4 1.9 2.9 0.0 0.0 1.3 1.8 1.7 3.0 0.9 1.2 1.0 1.8 1.8 0.9 22.8 1.9 1.8 4.2 15.6 2.6 12.1 0.0 19.3 0.3 1.1 2.8 2.3 10.2 3.4 1.5 17.9 3.2 6.0 21.9 3.3 0.0 2.6 3.9 1.0 9.0 0.0 1.9 23.7 0.0 12.9 3.5 0.8 4.4 5.2 3.6 3.7 13.6 0.4 0.0 3.0 3.4 22.5 5.8 1.2 0.5 2.9 11.6 2.4 1.7 7.9 0.0 3.1 2.6 1.7 3.5 2.1 0.6 2.2 3.1 2.0 17.9 1.4 FYCO1 "FLJ13335, ZFYVE7" ENSG00000163820 "FYVE and coiled-coil domain autophagy adaptor 1" Q9BQS8 3 45917899-45995824 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 263.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 89.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035526, HPA057966" Uncertain Enhanced Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA035526: AB_10672867, HPA057966: AB_2683567" "unprognostic (2.45e-1)" "unprognostic (6.62e-2)" "unprognostic (6.97e-3)" "unprognostic (1.14e-3)" "unprognostic (7.65e-2)" "unprognostic (1.23e-2)" "unprognostic (1.57e-2)" "unprognostic (4.53e-3)" "unprognostic (5.85e-2)" "unprognostic (8.85e-2)" "unprognostic (2.36e-1)" "unprognostic (2.98e-1)" "prognostic favorable (3.33e-11)" "unprognostic (2.90e-1)" "unprognostic (1.42e-1)" "unprognostic (2.89e-2)" "unprognostic (6.99e-2)" 16.7 13.0 10.5 9.7 12.0 6.5 13.4 9.6 9.4 23.1 11.3 42.0 8.0 25.6 10.3 21.3 15.4 18.7 66.8 8.6 10.3 10.7 10.8 14.7 8.6 15.5 10.8 23.1 12.7 20.3 7.6 8.2 14.8 19.3 10.7 33.0 14.9 22.9 263.3 19.3 14.4 28.2 15.1 10.2 20.4 3.3 11.9 10.5 16.5 104.6 8.2 39.6 16.9 15.1 10.8 10.3 3.0 13.0 27.9 21.8 4.9 10.2 23.7 13.1 14.6 5.6 9.3 7.9 5.6 14.2 12.7 7.9 8.5 17.0 15.7 3.3 9.0 11.4 8.7 6.3 19.0 8.8 7.9 24.3 16.7 21.1 20.5 20.3 26.7 13.4 7.4 11.3 9.5 6.7 9.0 5.5 4.5 8.8 9.8 3.1 8.3 4.4 15.9 37.2 2.2 3.4 6.4 20.0 17.6 4.4 9.7 5.7 20.8 5.0 5.9 17.0 5.7 6.4 4.4 2.7 17.2 11.1 9.6 0.7 0.5 0.3 2.0 0.5 2.7 0.2 1.2 2.1 0.2 0.2 0.5 0.7 0.4 1.5 0.3 1.3 1.2 0.7 10.5 12.0 9.6 9.4 8.6 10.3 15.5 10.8 14.8 15.1 11.9 15.1 9.5 28.9 13.7 12.4 4.8 4.1 4.8 5.6 3.4 11.2 8.5 4.8 89.3 8.6 13.0 16.5 35.5 4.3 8.7 6.8 3.9 8.8 0.1 6.4 8.9 9.3 9.6 6.9 0.8 8.3 2.2 14.0 12.8 11.2 2.5 14.9 11.4 9.2 4.1 0.0 0.8 7.6 2.0 5.8 4.6 1.6 12.8 5.1 10.6 10.3 4.0 20.0 6.2 8.0 21.2 11.0 2.5 17.7 3.0 17.3 8.7 6.2 18.6 37.1 6.6 20.8 12.8 2.3 0.8 8.4 4.1 2.9 12.7 6.1 6.2 7.9 FZD7 FzE3 ENSG00000155760 "Frizzled class receptor 7" O75084 2 202033855-202038441 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 30.9;Breast myoepithelial cells: 37.0;Cardiomyocytes: 21.1;Fibroblasts: 23.5;Proximal enterocytes: 21.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 30.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 42.8;BJ hTERT+: 48.4;CAPAN-2: 62.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059979, HPA069165, HPA076183" Approved Supported Vesicles NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA059979: , HPA069165: AB_2686096, HPA076183: " "unprognostic (3.44e-2)" "unprognostic (6.89e-2)" "unprognostic (9.30e-3)" "unprognostic (2.44e-3)" "unprognostic (4.92e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.71e-5)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-3)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (4.16e-2)" "unprognostic (2.05e-3)" 10.2 3.0 4.9 5.6 4.7 0.4 15.5 30.2 4.3 13.2 6.3 36.7 6.9 18.4 14.1 9.4 16.8 6.3 14.4 8.8 5.0 8.2 1.2 5.3 3.9 5.2 4.9 25.0 1.7 1.1 9.3 5.7 5.5 19.2 5.5 1.3 21.7 23.5 26.7 10.9 10.8 11.1 4.9 1.9 5.9 2.1 4.5 1.1 5.1 9.5 3.8 27.1 15.3 5.6 10.3 5.2 33.2 10.8 10.6 7.9 14.8 42.8 48.4 11.9 13.9 32.2 62.7 0.1 25.1 26.2 7.9 10.6 6.0 1.3 13.7 5.4 8.6 1.1 2.1 2.7 7.2 2.1 2.1 7.6 1.0 6.4 3.7 9.5 0.0 0.7 2.9 2.6 9.8 4.2 0.0 5.7 36.6 2.0 3.5 4.2 6.4 1.1 1.9 6.1 5.5 12.6 5.4 0.4 6.8 26.7 3.8 2.5 0.1 23.8 8.8 15.0 5.4 2.7 2.2 0.1 4.9 0.5 16.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.7 30.2 4.3 8.8 5.0 5.2 4.9 5.5 4.9 4.5 5.6 3.5 0.0 8.1 3.6 2.0 10.3 8.3 1.9 14.8 0.0 30.9 37.0 21.1 1.5 0.3 1.8 0.0 0.5 2.0 4.7 1.9 1.6 0.1 1.5 2.0 1.7 1.2 0.0 1.5 0.2 1.1 23.5 2.6 3.6 1.3 7.5 0.7 0.7 1.5 0.0 0.2 9.9 0.0 0.8 5.7 0.5 5.3 2.0 3.6 0.0 0.1 7.5 0.0 0.0 0.1 0.6 2.1 4.9 1.7 6.9 21.3 0.1 0.9 0.6 6.6 13.5 16.3 1.6 2.9 11.4 9.8 0.8 2.5 0.5 7.6 1.8 GAA ENSG00000171298 "Glucosidase alpha, acid" P10253 17 80101556-80119881 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 156.2;Extravillous trophoblasts: 143.9;Kupffer cells: 122.7;Syncytiotrophoblasts: 166.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 66.6;eosinophil: 22.8;intermediate monocyte: 50.3;myeloid DC: 39.7;neutrophil: 27.0;non-classical monocyte: 68.5" "Group enriched" "Detected in all" 10 "dendritic cells: 39.7;granulocytes: 27.0;monocytes: 68.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026970, HPA029126" Enhanced Approved Vesicles NA NA 3800000 "Cluster 14: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA026970: AB_2672065, HPA029126: AB_2672918" "unprognostic (1.13e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (7.66e-4)" "unprognostic (2.94e-2)" "unprognostic (1.14e-2)" "unprognostic (7.96e-2)" "unprognostic (2.05e-2)" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (1.29e-2)" "unprognostic (2.76e-1)" "unprognostic (1.46e-1)" "unprognostic (7.02e-2)" "unprognostic (2.38e-1)" "unprognostic (1.78e-2)" "unprognostic (1.18e-1)" 31.7 29.9 16.9 22.6 20.8 16.7 30.1 19.2 26.5 25.8 17.1 29.2 24.7 31.2 35.2 15.8 29.1 29.9 35.1 18.3 24.7 37.6 47.3 44.4 22.5 28.2 21.6 18.8 37.2 33.3 38.8 48.5 26.6 33.2 8.7 6.6 37.7 23.6 47.0 25.5 26.9 14.6 21.0 54.3 26.9 56.0 26.0 20.4 32.6 25.1 7.0 31.5 22.0 31.4 35.6 67.8 13.2 43.2 40.4 40.2 85.1 21.8 39.6 16.2 13.2 20.3 56.3 12.7 56.5 17.3 13.8 14.8 4.1 25.2 3.8 16.5 49.9 0.2 12.8 73.3 69.7 1.7 40.4 86.7 35.4 30.6 10.5 32.8 28.9 33.5 12.9 51.5 12.4 81.3 6.0 8.4 27.3 8.7 46.8 30.9 44.8 22.2 13.1 36.5 15.1 43.4 28.5 31.3 39.0 8.1 89.5 50.1 18.8 59.7 31.5 43.6 8.1 121.4 36.5 3.8 19.1 32.8 38.4 0.6 66.6 22.8 3.7 50.3 4.4 3.1 2.8 3.8 39.7 3.0 3.2 2.3 27.0 3.0 68.5 9.5 2.1 32.9 16.9 20.8 19.2 26.5 18.3 24.7 28.2 21.6 26.6 21.0 26.0 31.4 21.9 19.2 41.3 31.6 9.3 11.2 19.6 38.7 8.0 16.1 24.1 28.2 19.9 24.3 24.7 14.7 8.4 156.2 11.8 11.5 5.9 25.2 55.7 14.3 16.7 21.6 6.1 4.8 16.2 15.8 143.9 33.0 20.4 27.8 8.8 28.5 23.6 26.4 99.8 11.8 18.9 10.9 12.2 122.7 29.6 29.3 23.9 83.9 24.9 20.6 39.1 32.1 8.2 11.6 12.5 9.4 13.5 19.2 12.9 20.2 31.4 21.5 9.3 18.5 6.6 15.0 13.9 66.0 29.4 10.3 8.4 166.2 8.2 30.2 14.4 14.8 GABARAP "ATG8A, MM46" ENSG00000170296 "GABA type A receptor-associated protein" O95166 17 7240008-7242449 "Predicted intracellular proteins, Transporters" "Apoptosis, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 498.6;Ductal cells: 462.5;Plasma cells: 482.6;Squamous epithelial cells: 457.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065883 Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 59: Non-specific - Transcription" Vesicles "HPA065883: AB_2685574" "unprognostic (2.58e-1)" "unprognostic (4.55e-3)" "unprognostic (1.92e-1)" "unprognostic (9.08e-2)" "unprognostic (1.19e-1)" "unprognostic (4.30e-2)" "unprognostic (1.36e-1)" "unprognostic (2.57e-1)" "unprognostic (1.01e-1)" "unprognostic (1.58e-1)" "prognostic favorable (9.52e-5)" "unprognostic (1.85e-1)" "unprognostic (1.45e-2)" "unprognostic (2.09e-1)" "unprognostic (2.85e-2)" "unprognostic (1.22e-2)" "unprognostic (1.58e-1)" 609.8 848.2 777.0 344.7 799.2 478.8 610.9 826.8 1091.7 696.5 776.2 600.1 292.4 548.9 574.9 479.4 561.2 302.8 740.4 753.9 807.5 741.1 625.2 569.8 308.5 819.2 790.0 751.1 732.2 662.1 851.7 302.2 829.3 604.6 372.4 280.6 592.3 385.4 1001.1 662.8 496.8 341.4 817.6 651.6 658.9 604.5 803.0 389.2 552.3 916.4 411.0 534.0 547.5 862.7 233.5 342.1 598.0 404.5 887.1 999.5 227.0 377.1 645.5 330.1 491.2 141.9 200.6 233.9 233.2 672.0 430.6 206.9 428.1 329.7 441.7 421.8 474.4 182.8 301.3 377.3 858.3 118.7 369.6 1016.1 445.4 424.5 378.9 925.6 623.7 350.0 143.6 256.8 577.5 159.4 288.4 267.6 242.0 420.9 329.1 393.8 273.3 318.8 682.9 240.9 262.8 695.8 284.1 262.5 409.4 439.3 333.4 228.4 563.7 363.6 211.1 357.7 314.8 280.6 294.2 152.6 586.1 296.2 383.5 2968.2 4092.7 3746.6 766.9 3665.8 796.1 1262.2 906.3 810.4 3152.3 1156.6 812.9 765.5 7095.7 734.6 3213.5 2410.2 1132.5 4745.4 777.0 799.2 826.8 1091.7 753.9 807.5 819.2 790.0 829.3 817.6 803.0 862.7 24.0 89.8 120.1 44.4 183.6 20.8 3.9 21.3 498.6 2.4 64.1 31.9 0.5 54.3 81.3 27.6 0.0 24.3 35.8 302.0 43.0 462.5 24.1 25.5 32.4 61.5 396.5 179.3 36.7 309.6 31.1 124.2 264.6 24.8 150.0 6.9 45.0 39.9 78.2 1.7 37.7 314.3 34.6 147.0 60.8 71.3 21.1 397.4 33.8 43.1 399.2 15.1 32.0 21.1 87.8 375.2 374.3 13.9 482.6 6.0 384.7 72.0 166.4 3.0 6.6 5.2 74.2 22.1 5.8 457.2 23.2 52.9 105.2 5.2 237.1 4.9 GABARAPL1 "APG8L, ATG8B, ATG8L, gec1" ENSG00000139112 "GABA type A receptor associated protein like 1" Q9H0R8 12 10212458-10223128 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 432.4;Syncytiotrophoblasts: 929.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 62.1" "Group enriched" "Detected in many" 5 "granulocytes: 62.1;NK-cells: 22.6;T-cells: 26.7" "Cell line enhanced" "Detected in many" "HHSteC: 255.7;SiHa: 231.5;SuSa: 557.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051386, HPA065883" Approved Approved Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA051386: AB_2681463, HPA065883: AB_2685574" "unprognostic (9.58e-3)" "unprognostic (1.16e-1)" "unprognostic (4.23e-2)" "unprognostic (1.06e-1)" "unprognostic (8.46e-2)" "unprognostic (1.85e-3)" "prognostic favorable (2.36e-4)" "unprognostic (2.90e-1)" "unprognostic (6.38e-2)" "unprognostic (2.79e-2)" "unprognostic (9.25e-3)" "unprognostic (1.72e-1)" "prognostic favorable (8.19e-8)" "unprognostic (5.42e-2)" "unprognostic (2.57e-2)" "unprognostic (1.10e-1)" "unprognostic (1.77e-1)" 185.4 97.7 115.0 33.6 131.3 164.3 150.7 102.6 215.8 75.2 105.2 101.9 40.8 77.7 125.3 44.1 91.1 75.5 334.3 141.9 155.8 314.9 207.4 146.0 15.2 145.7 105.6 157.9 138.2 126.0 218.2 190.1 135.9 92.9 35.0 327.0 118.1 69.8 381.8 71.5 67.1 64.7 90.9 42.3 133.6 37.4 123.2 21.8 93.4 163.3 14.2 107.5 82.8 138.4 8.7 18.3 36.2 34.2 200.8 57.3 30.2 200.0 91.8 33.6 43.9 79.5 30.1 2.0 16.4 215.4 84.8 54.6 32.0 24.2 24.5 6.1 29.9 11.8 115.4 22.0 255.7 14.8 13.3 101.0 52.0 25.9 20.4 96.7 82.5 23.7 14.9 0.5 14.4 0.7 12.4 15.2 88.3 1.9 18.2 0.9 66.1 0.9 139.7 21.6 3.5 7.6 231.5 36.8 71.5 557.0 16.9 8.8 113.1 10.9 36.6 17.4 9.6 35.3 60.4 55.8 36.5 6.7 16.2 53.6 4.8 43.0 26.7 2.7 8.9 0.2 3.6 16.3 2.9 0.1 3.4 14.2 62.1 22.6 6.7 1.1 5.8 6.5 115.0 131.3 102.6 215.8 141.9 155.8 145.7 105.6 135.9 90.9 123.2 138.4 216.8 60.9 35.7 15.0 23.5 62.8 196.6 57.1 101.3 118.3 45.0 26.0 197.8 72.9 33.6 58.8 154.3 310.8 171.8 38.5 432.4 62.5 295.1 57.8 75.0 88.0 71.0 61.7 45.5 57.2 31.1 128.9 61.7 143.9 17.7 15.4 63.9 112.1 72.0 89.2 41.4 37.6 75.3 73.1 56.4 70.3 25.7 111.6 74.7 18.7 24.6 114.2 25.7 13.0 26.6 45.4 31.5 24.5 57.2 130.7 55.0 250.3 16.1 237.6 19.7 96.8 85.2 10.0 8.8 32.6 42.3 929.0 125.6 25.8 11.5 169.0 GALNT9 GALNAC-T9 ENSG00000182870 "Polypeptide N-acetylgalactosaminyltransferase 9" Q9HCQ5 12 132196372-132329589 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;kidney: 9.4;thyroid gland: 13.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.7;Collecting duct cells: 27.6;Excitatory neurons: 37.1;Inhibitory neurons: 13.1;Proximal tubular cells: 8.2" "Group enriched" "Detected in some" 5 "glioma: 0.9;ovarian cancer: 0.5;renal cancer: 1.6;thyroid cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-87 MG: 13.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075016 Approved Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA075016: AB_2686729" "unprognostic (1.13e-1)" "unprognostic (3.47e-2)" "unprognostic (1.47e-1)" "unprognostic (6.44e-2)" "unprognostic (1.03e-1)" "unprognostic (6.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.32e-2)" "unprognostic (2.03e-1)" "unprognostic (1.64e-3)" "unprognostic (2.85e-1)" "unprognostic (6.62e-2)" "unprognostic (5.17e-2)" "unprognostic (1.89e-1)" "unprognostic (1.71e-1)" "unprognostic (3.89e-2)" "unprognostic (5.69e-2)" 9.3 1.2 8.3 0.1 11.9 0.0 0.1 19.9 22.5 3.9 0.0 1.5 0.2 0.8 2.3 0.1 1.9 0.0 0.8 11.2 2.9 9.4 0.2 0.5 0.3 6.1 4.4 1.3 0.1 0.2 8.4 0.0 5.9 1.0 0.0 0.6 0.2 0.3 0.1 0.1 0.5 0.0 1.0 0.9 0.6 0.7 9.6 0.1 13.0 0.0 0.0 0.5 0.8 11.0 0.0 0.9 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 13.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 11.9 19.9 22.5 11.2 2.9 6.1 4.4 5.9 1.0 9.6 11.0 0.0 0.0 0.6 2.6 0.0 0.0 0.5 0.0 0.0 7.7 0.1 0.0 1.6 0.0 0.0 27.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.4 1.3 0.0 0.0 37.1 0.0 0.0 2.7 0.0 0.8 1.3 0.0 0.0 0.0 0.2 3.3 13.1 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.0 5.6 0.0 1.7 0.0 2.0 2.9 0.1 0.0 1.9 0.0 0.6 0.0 8.2 0.0 3.3 0.0 0.9 0.6 0.0 0.1 0.0 0.1 0.1 0.0 2.0 0.1 0.8 GASK1A "C3orf41, DKFZP434B172, FAM198A" ENSG00000144649 "Golgi associated kinase 1A" Q9UFP1 3 42979267-43060211 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.4;Extravillous trophoblasts: 2.6;Fibroblasts: 1.8;Hofbauer cells: 3.9;Syncytiotrophoblasts: 2.7" "Cancer enhanced" "Detected in many" "glioma: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 3.1;RPMI-8226: 3.4;SK-BR-3: 2.6;T-47d: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047726 Approved Supported Vesicles "Secreted - unknown location" NA NA 600000 "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA047726: AB_10960554" "unprognostic (2.16e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (2.93e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.65e-2)" "unprognostic (5.79e-2)" "unprognostic (2.69e-1)" "unprognostic (6.21e-2)" "unprognostic (2.02e-1)" "unprognostic (1.50e-1)" "unprognostic (1.57e-4)" "unprognostic (4.45e-2)" "unprognostic (2.09e-2)" "unprognostic (3.49e-2)" "unprognostic (3.81e-1)" 5.5 2.1 4.9 2.5 6.4 0.0 4.2 6.3 3.8 10.6 4.9 3.4 0.7 9.8 2.2 1.8 11.3 5.3 1.7 4.1 5.9 1.0 13.1 3.1 0.7 8.8 7.7 6.8 2.0 0.1 3.0 2.0 7.6 2.6 1.0 3.9 2.6 2.2 1.4 1.7 2.1 6.0 6.3 0.9 3.4 2.9 10.0 0.6 2.1 0.8 0.3 3.2 3.9 5.2 0.0 0.0 0.0 3.1 0.1 0.0 1.1 0.2 0.3 0.0 0.0 0.1 0.9 0.0 1.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 1.9 0.7 0.0 0.0 0.6 0.4 1.2 0.8 0.0 0.4 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.8 0.0 1.9 0.0 0.0 0.0 0.0 3.4 0.0 0.5 0.1 0.3 0.0 2.6 0.0 0.1 6.7 0.9 0.0 0.4 0.6 1.4 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.9 6.4 6.3 3.8 4.1 5.9 8.8 7.7 7.6 6.3 10.0 5.2 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 GCM1 "GCMA, hGCMa" ENSG00000137270 "Glial cells missing transcription factor 1" Q9NP62 6 53126961-53148841 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "placenta: 20.2" "Group enriched" "Detected in some" 7 "Extravillous trophoblasts: 230.3;Syncytiotrophoblasts: 266.1" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 5 "BEWO: 39.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA011343, HPA073469" Enhanced Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA011343: AB_2668489, HPA073469: " "unprognostic (2.81e-2)" "unprognostic (4.09e-2)" "unprognostic (1.89e-2)" "unprognostic (1.53e-1)" "unprognostic (3.17e-1)" "unprognostic (7.68e-2)" "unprognostic (8.47e-3)" "unprognostic (2.83e-2)" "unprognostic (2.81e-1)" "unprognostic (4.04e-2)" "unprognostic (1.42e-1)" "unprognostic (5.98e-2)" "unprognostic (1.29e-4)" "unprognostic (1.86e-1)" "unprognostic (7.42e-2)" "unprognostic (2.96e-2)" 0.1 0.1 0.4 0.1 0.2 0.4 0.1 0.3 0.7 0.0 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.3 0.1 1.3 0.0 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.0 20.2 0.2 0.0 0.0 0.4 0.1 0.0 3.6 0.1 0.1 0.0 0.0 0.4 0.1 0.6 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.1 0.2 0.2 0.0 0.0 39.2 0.0 0.0 0.0 0.0 1.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.2 0.0 0.1 0.0 8.2 0.1 0.2 0.0 0.1 0.2 0.1 0.1 0.4 0.3 0.2 0.0 0.1 0.1 0.2 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 1.4 0.1 0.1 0.0 0.0 0.0 0.4 0.2 0.3 0.7 0.3 0.1 0.1 0.1 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.0 33.8 0.0 0.0 0.0 0.3 2.0 0.4 0.0 0.4 0.0 0.0 0.1 0.2 230.3 0.5 0.0 0.6 0.0 0.0 0.0 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 11.7 0.0 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 266.1 0.1 0.0 0.0 0.1 GCSH ENSG00000140905 "Glycine cleavage system protein H" P23434 16 81081945-81096395 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 553.4;Extravillous trophoblasts: 1476.4;Proximal tubular cells: 655.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA041368, HPA057079" Supported Approved Vesicles "Intracellular and membrane" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA041368: AB_10804001, HPA057079: " "unprognostic (4.09e-2)" "unprognostic (2.98e-2)" "unprognostic (2.29e-1)" "unprognostic (2.47e-3)" "unprognostic (2.55e-3)" "unprognostic (4.87e-2)" "unprognostic (1.38e-1)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (1.96e-2)" "unprognostic (6.92e-2)" "unprognostic (2.80e-2)" "prognostic favorable (6.26e-6)" "unprognostic (1.12e-2)" "unprognostic (2.59e-1)" "unprognostic (6.31e-2)" "unprognostic (6.47e-2)" 28.7 20.1 58.9 6.9 66.5 6.3 24.2 62.9 113.8 18.2 50.8 16.0 7.2 17.5 68.9 15.5 19.8 11.7 38.1 55.8 60.9 78.2 118.9 10.8 6.7 60.1 66.0 18.4 19.7 31.0 14.3 26.0 61.1 18.7 13.0 15.6 15.6 16.7 59.3 10.1 9.5 11.8 61.7 6.3 17.5 7.4 63.7 10.4 96.4 63.6 9.3 18.3 15.2 67.8 63.6 28.3 82.4 37.0 40.4 30.9 175.5 35.9 26.4 43.3 20.6 37.0 57.2 17.2 32.3 15.9 31.9 33.3 64.5 36.5 71.6 4.7 86.7 21.8 34.9 114.6 45.7 70.3 24.1 32.0 47.8 26.8 53.7 13.0 22.3 45.1 86.3 3.4 42.9 67.7 45.9 138.8 113.0 49.6 57.5 72.7 44.1 25.5 98.4 56.4 43.7 45.3 53.3 32.9 70.8 63.9 48.3 33.2 19.8 27.6 49.3 44.0 37.8 14.7 31.8 102.1 18.2 41.3 22.6 3.6 1.3 1.3 2.8 2.1 4.6 3.5 2.6 4.0 3.9 2.5 4.4 5.9 1.7 7.0 1.7 10.8 2.2 2.4 58.9 66.5 62.9 113.8 55.8 60.9 60.1 66.0 61.1 61.7 63.7 67.8 31.1 3.2 5.9 16.3 24.8 29.1 94.6 73.6 52.3 43.7 97.9 115.6 12.9 44.3 31.4 80.9 37.5 553.4 13.8 15.3 295.4 70.0 32.4 34.8 128.3 31.9 26.4 71.1 12.6 42.5 1476.4 61.6 31.1 55.2 36.3 38.5 33.2 352.0 118.8 38.7 11.9 34.3 67.1 19.7 34.6 19.5 140.8 18.8 85.4 4.7 17.7 215.8 19.6 19.6 35.2 42.3 17.8 141.1 51.7 123.9 13.7 655.9 20.0 45.7 32.9 46.2 50.2 20.7 77.3 78.4 27.1 228.8 16.3 114.5 49.4 69.8 GDF10 BMP-3b ENSG00000266524 "Growth differentiation factor 10" P55107 10 47300197-47313577 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 19.6;retina: 18.4" "Group enriched" "Detected in some" 5 "Bipolar cells: 20.9;Cone photoreceptor cells: 16.7;Fibroblasts: 25.7;Rod photoreceptor cells: 34.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 13.5;MOLT-4: 3.0;SH-SY5Y: 5.5" "Region enriched" "Detected in all" 8 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA015498 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA015498: AB_1849584" "unprognostic (4.34e-2)" "unprognostic (3.10e-1)" "unprognostic (1.41e-1)" "unprognostic (5.09e-1)" "unprognostic (3.17e-1)" "unprognostic (9.84e-3)" "unprognostic (1.37e-2)" "unprognostic (2.26e-2)" "unprognostic (1.55e-1)" "unprognostic (4.08e-2)" "unprognostic (1.15e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-7)" "unprognostic (3.49e-2)" "unprognostic (1.48e-1)" "unprognostic (2.59e-3)" "unprognostic (2.63e-1)" 12.4 3.2 5.4 0.3 5.4 0.0 9.7 5.1 4.0 2.6 0.6 2.5 0.0 4.2 0.2 2.4 1.6 2.2 4.4 5.9 3.3 0.1 0.1 19.6 0.8 2.6 5.8 0.3 13.3 0.0 0.7 0.0 1.4 2.2 0.3 18.4 8.8 0.2 2.2 3.1 0.6 0.4 2.5 0.1 1.8 7.1 5.5 0.4 9.7 10.4 1.0 1.3 1.7 3.7 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.4 5.1 4.0 5.9 3.3 2.6 5.8 1.4 2.5 5.5 3.7 2.4 0.0 0.6 0.0 0.0 0.4 0.1 0.0 0.0 20.9 0.1 0.0 0.8 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.6 0.2 25.7 0.0 0.0 1.3 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.0 0.0 2.6 0.7 0.9 0.2 1.8 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 0.0 0.6 1.6 0.4 1.3 0.0 0.9 0.0 0.4 0.0 0.0 0.0 GDF11 "BMP-11, BMP11" ENSG00000135414 "Growth differentiation factor 11" O95390 12 55743122-55757264 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 26.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 76.6;Cone photoreceptor cells: 77.2;Horizontal cells: 57.2;Rod photoreceptor cells: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HMC-1: 127.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060985, HPA069609" Approved Approved Vesicles "Secreted to blood" No No 46400 340000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA060985: AB_2684403, HPA069609: AB_2686159" "unprognostic (5.21e-2)" "unprognostic (1.62e-1)" "unprognostic (3.20e-2)" "unprognostic (2.41e-2)" "unprognostic (2.78e-2)" "unprognostic (3.39e-1)" "unprognostic (2.13e-1)" "unprognostic (2.62e-2)" "unprognostic (8.96e-3)" "unprognostic (1.23e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.69e-1)" "unprognostic (1.62e-2)" "unprognostic (1.27e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" "unprognostic (9.48e-2)" 3.6 4.0 22.5 3.7 17.5 1.8 2.3 16.4 17.8 6.8 15.9 5.4 1.6 7.6 2.0 2.4 5.0 4.6 7.5 18.1 18.5 3.0 1.3 3.6 2.8 22.0 26.6 5.7 2.9 2.9 4.7 2.0 20.9 6.0 1.6 21.6 4.8 9.4 1.8 1.5 3.7 4.6 18.3 5.6 2.7 1.1 22.3 4.6 3.6 2.0 1.8 5.9 3.4 17.7 4.9 7.6 32.8 18.6 24.4 17.8 8.2 10.1 9.5 12.5 10.7 26.0 2.1 9.5 13.0 10.5 5.9 4.6 25.0 18.0 4.3 18.2 22.7 11.7 12.3 4.1 4.9 9.8 127.7 17.2 1.0 18.3 5.2 14.0 16.4 12.7 13.2 30.1 16.0 9.2 16.0 8.5 26.4 0.3 18.9 25.1 8.9 5.9 7.7 6.6 22.2 13.6 6.2 2.8 2.6 13.3 10.7 10.7 10.1 15.0 22.9 11.9 7.4 8.1 2.6 4.9 8.0 9.7 10.8 0.2 0.2 0.5 1.2 0.1 1.0 0.7 0.7 0.7 0.2 0.7 0.6 0.8 0.3 0.2 0.4 0.7 0.5 0.1 22.5 17.5 16.4 17.8 18.1 18.5 22.0 26.6 20.9 18.3 22.3 17.7 8.4 0.0 1.1 19.2 10.9 0.5 9.8 0.6 4.0 76.6 6.3 6.6 25.6 1.5 0.9 0.0 77.2 3.6 16.6 1.5 0.0 5.0 0.6 9.9 35.2 8.0 10.7 11.1 4.3 1.4 5.3 13.3 3.1 18.0 5.7 7.6 6.4 0.2 1.6 57.2 10.8 1.9 0.0 1.9 0.7 0.8 9.0 4.4 3.6 1.9 4.1 30.6 22.6 17.1 3.2 3.3 4.1 5.7 4.1 9.8 3.4 0.5 0.1 53.1 13.1 31.1 18.1 2.9 4.1 3.0 0.9 4.7 18.9 7.2 2.2 6.2 GDF7 BMP12 ENSG00000143869 "Growth differentiation factor 7" Q7Z4P5 2 20667144-20679243 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 9.8;seminal vesicle: 22.4" "Group enriched" "Detected in some" 12 "Endometrial stromal cells: 137.0;Granulosa cells: 83.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.7;Hep G2: 4.4;RT4: 8.3;SH-SY5Y: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA069106 Approved Vesicles "Secreted in other tissues" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA069106: " "unprognostic (1.35e-1)" "unprognostic (9.93e-3)" "unprognostic (5.10e-1)" "unprognostic (2.44e-3)" "unprognostic (1.35e-1)" "unprognostic (2.06e-3)" "unprognostic (8.63e-3)" "unprognostic (6.31e-3)" "unprognostic (8.00e-3)" "unprognostic (3.85e-1)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.28e-3)" "unprognostic (8.02e-3)" "unprognostic (2.05e-1)" "unprognostic (3.44e-2)" "unprognostic (1.89e-3)" 0.4 0.4 0.2 1.0 0.5 0.2 0.1 0.0 2.5 9.8 0.0 0.5 0.2 7.2 3.3 0.9 0.7 0.6 0.8 0.4 0.1 3.6 5.0 0.4 2.3 0.3 0.1 0.3 0.6 0.1 0.3 0.8 0.0 3.8 0.2 0.1 0.1 22.4 0.0 1.3 1.6 1.1 0.0 1.3 0.7 0.2 0.3 0.2 0.2 0.6 1.8 1.1 6.6 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.7 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 1.2 8.3 0.0 3.3 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 2.5 0.4 0.1 0.3 0.1 0.0 0.0 0.3 0.6 0.1 6.4 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.5 0.0 0.0 8.8 2.8 3.1 5.5 0.0 0.0 0.1 0.1 1.9 0.1 0.1 3.5 137.0 1.8 0.0 2.7 0.2 0.0 0.1 1.3 0.0 2.9 0.0 83.7 0.0 8.2 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 0.0 4.1 0.7 0.0 0.0 0.3 7.1 0.5 1.0 0.0 0.0 0.0 0.8 0.0 0.0 1.5 GFPT2 GFAT2 ENSG00000131459 "Glutamine-fructose-6-phosphate transaminase 2" O94808 5 180300698-180353336 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 30.4;Fibroblasts: 77.9;Skeletal myocytes: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.5" "Lineage enriched" "Detected in single" 35 "T-cells: 3.5" "Cell line enhanced" "Detected in many" "ASC diff: 119.1;ASC TERT1: 202.3;GAMG: 152.5;HSkMC: 130.7;hTEC/SVTERT24-B: 248.0;U-87 MG: 426.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056892, HPA059910" Uncertain Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA056892: AB_2683266, HPA059910: AB_2684157" "unprognostic (3.48e-1)" "prognostic unfavorable (9.09e-4)" "unprognostic (1.91e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (3.39e-3)" "unprognostic (3.05e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (7.65e-2)" "unprognostic (2.73e-2)" "unprognostic (4.50e-2)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.58e-14)" "unprognostic (3.67e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.52e-3)" 112.4 7.0 14.2 18.6 14.8 0.1 23.0 19.7 17.6 24.8 14.1 18.0 1.6 15.9 7.7 5.7 35.8 16.4 27.8 14.9 16.8 6.8 2.1 25.2 2.8 27.8 15.7 33.4 12.4 4.6 5.1 6.5 21.5 15.6 3.2 2.9 7.1 8.2 4.6 8.4 11.3 11.3 16.8 1.9 14.6 8.6 15.7 1.2 10.8 7.1 3.5 38.3 17.9 20.4 0.1 27.7 21.5 28.0 119.1 202.3 2.3 3.5 0.7 2.3 0.8 0.7 0.1 0.0 1.4 23.2 152.5 0.4 11.8 0.2 1.4 2.6 4.2 0.0 13.7 0.0 49.4 0.0 0.2 130.7 1.0 248.0 0.7 41.7 40.7 1.0 0.0 0.4 107.7 4.2 0.1 0.0 45.7 0.3 12.3 0.6 0.2 0.0 0.0 0.0 1.0 1.6 43.0 0.8 1.4 25.0 1.9 0.3 19.5 67.9 10.7 44.3 52.2 0.1 0.1 0.0 426.7 0.0 1.5 0.0 0.0 0.0 0.7 0.0 3.5 0.0 0.3 1.2 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 14.2 14.8 19.7 17.6 14.9 16.8 27.8 15.7 21.5 16.8 15.7 20.4 4.1 3.2 4.8 13.4 0.8 7.4 0.4 0.2 3.4 0.0 3.2 6.3 3.0 5.7 3.2 1.8 0.0 1.1 3.5 0.4 1.9 1.0 5.7 2.0 30.4 1.9 0.0 0.0 20.0 0.8 0.5 77.9 6.6 1.9 1.3 0.4 1.4 0.0 0.5 0.0 12.1 0.5 0.0 0.3 9.6 3.5 10.2 1.7 8.8 4.7 0.0 6.1 0.0 10.6 6.5 0.4 0.0 18.8 2.5 1.7 0.0 0.4 1.5 0.1 0.0 27.3 17.6 10.1 8.3 1.7 4.3 2.7 8.9 0.0 0.1 0.6 GFRA2 "GDNFRB, NTNRA, RETL2, TRNR2" ENSG00000168546 "GDNF family receptor alpha 2" O00451 8 21690398-21812357 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.4;thyroid gland: 8.7" "Group enriched" "Detected in some" 4 "Early spermatids: 91.9;Horizontal cells: 220.4;Late spermatids: 238.1" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 6.2" "Region enhanced" "Detected in many" "cerebral cortex: 5.0" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 9.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.5;monocytes: 9.2" "Cell line enhanced" "Detected in some" "HEL: 9.1;HMC-1: 21.4;WM-115: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024704, CAB032791" Uncertain Approved Vesicles "Intracellular and membrane" NA NA 9000000 "Cluster 7: Monocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB032791: AB_2110428, HPA024704: AB_1849629" "unprognostic (4.24e-2)" "unprognostic (1.11e-2)" "unprognostic (4.02e-1)" "unprognostic (3.46e-2)" "unprognostic (3.93e-2)" "unprognostic (1.08e-2)" "unprognostic (7.48e-4)" "unprognostic (2.87e-1)" "unprognostic (6.11e-2)" "unprognostic (4.40e-3)" "unprognostic (2.11e-3)" "unprognostic (7.82e-2)" "unprognostic (1.50e-4)" "unprognostic (8.45e-4)" "unprognostic (1.74e-1)" "unprognostic (4.68e-2)" "unprognostic (9.63e-3)" 2.4 1.8 1.2 2.0 1.0 0.6 0.6 0.0 5.0 2.6 0.0 2.1 1.9 0.5 0.2 1.5 1.3 0.6 1.0 1.5 2.2 0.2 0.9 1.2 1.6 0.0 0.8 0.3 0.3 0.1 0.4 7.1 0.0 0.4 1.1 2.6 0.9 1.5 0.1 0.5 1.8 2.0 0.0 7.5 1.0 9.4 1.8 1.1 8.7 0.6 0.8 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.9 0.8 0.0 9.2 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 0.4 0.0 1.3 0.0 0.0 0.9 1.2 1.0 0.0 5.0 1.5 2.2 0.0 0.8 0.0 0.0 1.8 0.0 0.3 0.0 1.8 1.3 0.1 1.8 0.2 0.0 0.0 4.3 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 91.9 0.0 1.2 0.3 0.0 0.0 39.5 0.0 0.1 1.8 0.0 0.1 1.3 0.0 0.7 0.2 0.6 220.4 6.5 0.0 0.0 30.6 25.2 238.1 0.6 11.8 0.0 3.7 0.5 1.9 0.0 2.5 1.1 0.0 0.0 1.9 0.1 0.1 0.0 0.0 0.0 2.1 6.6 0.7 1.8 1.2 7.0 0.0 0.9 0.3 0.2 0.1 0.0 0.1 GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24594811-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis, Lipid metabolism" "Acyltransferase, Hydrolase, Protease, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 174.8;liver: 115.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 80.1;Cholangiocytes: 48.6;Distal enterocytes: 54.1;Ductal cells: 82.6;Hepatocytes: 40.8;Proximal enterocytes: 111.7;Proximal tubular cells: 62.9" "Cancer enhanced" "Detected in all" "renal cancer: 37.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 103.6;Karpas-707: 165.8;OE19: 169.5;RPMI-8226: 210.3;RPTEC TERT1: 203.2" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles "Intracellular and membrane" NA NA 3600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favorable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" 3.3 2.4 5.5 6.4 6.7 12.0 24.7 7.0 7.5 28.7 5.1 20.3 84.7 3.0 72.0 3.3 3.3 47.1 7.2 5.1 5.1 174.8 115.7 42.6 5.4 7.2 6.6 3.2 63.1 0.2 5.5 2.4 7.8 48.8 11.0 1.6 9.9 21.6 1.9 4.1 80.4 2.2 5.9 13.3 31.3 18.4 7.1 6.5 15.9 0.4 6.2 5.7 4.3 9.2 1.0 79.7 1.0 0.3 0.0 0.5 2.2 0.5 1.7 0.8 1.0 11.7 18.3 1.0 16.2 0.1 14.8 11.0 6.2 0.8 0.5 103.6 12.3 0.6 40.8 64.3 5.5 1.5 33.2 2.1 0.9 2.5 1.7 1.4 0.5 19.0 8.4 165.8 1.0 1.7 1.6 52.4 6.4 169.5 0.7 0.7 6.8 210.3 203.2 2.9 0.5 1.2 0.4 33.3 0.8 22.2 32.4 39.6 6.4 10.6 9.3 46.6 0.9 48.2 18.4 0.7 19.0 58.7 0.5 4.8 12.3 0.2 1.0 6.0 2.9 2.2 5.0 2.4 6.5 0.2 0.6 1.4 15.9 4.9 4.0 0.1 6.5 5.6 5.5 6.7 7.0 7.5 5.1 5.1 7.2 6.6 7.8 5.9 7.1 9.2 0.2 80.1 22.8 3.3 2.8 0.8 0.1 0.3 4.6 0.5 5.9 2.3 0.7 48.6 4.9 1.8 0.0 1.4 0.7 54.1 1.9 82.6 1.8 1.2 0.6 0.7 1.2 5.3 4.4 8.1 0.4 3.9 15.3 5.1 5.7 0.1 1.8 40.8 4.9 0.0 4.1 4.4 4.1 2.5 1.7 6.7 0.0 2.9 1.8 1.0 5.8 2.5 0.0 1.5 5.7 20.9 20.1 0.4 12.8 2.0 111.7 62.9 1.6 0.1 0.0 0.1 1.0 0.6 0.8 0.4 0.4 0.8 4.0 0.0 6.5 0.1 GGT2 GGT ENSG00000133475 "Gamma-glutamyltransferase 2" P36268 22 21207973-21227637 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 8.7;thyroid gland: 8.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 7.2;Early spermatids: 5.6;Late spermatids: 18.7;Proximal tubular cells: 3.4" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 1.6;HeLa: 3.5;Karpas-707: 1.3;U-2197: 8.9" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (4.27e-1)" "unprognostic (6.91e-2)" "unprognostic (7.03e-2)" "unprognostic (8.13e-2)" "unprognostic (1.01e-2)" "unprognostic (2.38e-5)" "unprognostic (1.05e-3)" "unprognostic (5.85e-4)" "unprognostic (7.97e-3)" "unprognostic (8.84e-2)" "unprognostic (1.16e-1)" "unprognostic (6.39e-2)" "unprognostic (2.39e-1)" "unprognostic (1.48e-2)" "unprognostic (3.46e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.7 0.0 0.2 0.1 0.0 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.1 1.5 0.0 0.0 0.5 0.4 0.0 0.1 0.0 0.2 1.0 0.1 0.0 8.5 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 1.6 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.6 0.0 0.9 0.0 0.0 0.0 0.3 0.3 8.9 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.0 3.2 7.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.6 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 3.4 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GIPR ENSG00000010310 "Gastric inhibitory polypeptide receptor" P48546 19 45668221-45683722 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 22.7" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 29.9;Gastric mucus-secreting cells: 28.1;Respiratory ciliated cells: 44.5;Rod photoreceptor cells: 17.4" "Cancer enriched" "Detected in many" 5 "pancreatic cancer: 4.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 9.8;HMC-1: 20.6;SCLC-21H: 13.9;U-266/70: 16.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB022710, HPA068054" Uncertain Uncertain Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "CAB022710: , HPA068054: " "unprognostic (2.40e-2)" "unprognostic (9.03e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-2)" "unprognostic (2.65e-1)" "unprognostic (3.70e-4)" "unprognostic (1.82e-2)" "unprognostic (2.94e-2)" "unprognostic (1.42e-1)" "unprognostic (1.72e-2)" "unprognostic (4.85e-3)" "unprognostic (2.78e-1)" "unprognostic (1.72e-2)" "unprognostic (1.19e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-2)" "unprognostic (2.59e-2)" 10.0 0.3 1.8 3.1 2.6 2.0 9.0 2.3 3.3 2.5 2.7 6.9 3.7 0.3 0.7 2.5 10.2 1.4 15.2 1.8 2.7 3.8 0.7 5.6 2.7 4.1 4.7 0.1 10.8 5.6 0.4 0.2 4.5 7.1 4.9 13.1 7.8 0.4 0.3 4.2 4.2 0.3 1.7 4.0 22.7 0.2 4.4 0.6 2.5 0.0 2.4 2.6 3.4 4.4 0.7 0.4 1.3 0.7 0.6 0.0 0.1 1.0 0.8 0.0 0.7 0.4 3.9 1.9 0.6 0.8 0.7 2.0 0.3 0.2 0.1 9.8 0.3 1.6 1.0 0.3 0.1 0.6 20.6 0.0 0.3 0.1 0.0 1.8 0.0 2.1 4.5 2.2 0.0 0.2 0.1 1.1 0.0 2.9 0.7 0.5 0.4 4.4 0.5 0.9 13.9 1.2 0.0 0.8 0.2 0.5 2.0 3.1 0.4 0.0 0.5 0.3 0.2 16.7 0.2 0.4 0.6 1.5 0.3 1.1 0.1 0.5 0.5 0.2 0.1 0.2 0.2 0.3 0.2 0.3 0.2 0.3 0.5 0.9 0.0 0.2 0.4 0.2 1.8 2.6 2.3 3.3 1.8 2.7 4.1 4.7 4.5 1.7 4.4 4.4 1.4 3.2 6.3 0.0 1.0 0.9 3.4 2.9 0.0 0.3 2.0 0.5 4.0 5.7 9.8 5.5 0.0 0.0 3.7 13.2 0.0 2.2 0.4 7.1 0.1 0.5 29.9 0.0 0.2 3.6 0.1 0.5 28.1 0.7 1.3 0.1 0.0 0.0 0.1 0.0 0.4 6.8 4.1 0.0 7.8 0.2 0.0 1.4 0.0 0.0 0.5 0.2 1.0 0.0 5.0 5.6 11.3 0.0 4.0 1.5 0.3 0.1 44.5 17.4 13.1 0.3 3.5 0.2 0.3 1.5 0.4 0.1 2.1 0.1 1.9 2.8 GLTPD2 ENSG00000182327 "Glycolipid transfer protein domain containing 2" A6NH11 17 4788964-4790589 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 73.8" "Group enriched" "Detected in some" 5 "Hepatocytes: 83.7;Proximal tubular cells: 135.8" "Cancer enriched" "Detected in many" 5 "liver cancer: 25.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 3.4;CACO-2: 9.2;Hep G2: 13.7;MCF7: 4.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA058295, HPA065267" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 150000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA058295: AB_2683671, HPA065267: AB_2685451" "unprognostic (4.00e-1)" "unprognostic (1.93e-1)" "unprognostic (1.95e-3)" "unprognostic (1.70e-1)" "unprognostic (3.03e-2)" "unprognostic (1.79e-4)" "unprognostic (1.40e-1)" "unprognostic (1.45e-2)" "unprognostic (4.16e-3)" "unprognostic (2.33e-2)" "unprognostic (5.62e-4)" "unprognostic (7.80e-2)" "unprognostic (2.62e-1)" "unprognostic (4.25e-1)" "unprognostic (4.79e-1)" "unprognostic (1.71e-4)" "unprognostic (7.59e-3)" 0.5 0.5 1.3 0.5 1.1 1.5 0.3 2.3 2.7 0.4 0.0 0.5 10.1 0.5 0.0 0.8 0.4 0.3 0.2 1.0 2.1 12.0 73.8 0.4 0.1 3.1 2.8 0.3 0.7 0.2 0.8 0.1 2.0 0.4 0.0 0.3 1.0 0.0 1.3 1.7 6.2 0.0 0.4 1.1 1.1 0.1 1.5 0.0 0.2 0.0 0.0 0.5 0.5 1.4 0.5 1.8 0.1 1.5 0.0 0.0 3.4 0.4 0.0 0.0 0.0 9.2 0.6 0.8 0.9 0.0 0.3 1.7 0.0 0.0 0.0 1.7 1.2 0.1 0.7 13.7 0.1 0.2 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.5 0.4 0.0 4.1 0.1 0.1 0.2 0.6 0.7 0.7 0.5 0.2 0.0 0.7 1.1 0.7 1.6 0.3 0.4 0.0 1.0 0.1 1.7 0.5 0.7 0.4 0.3 0.1 0.5 0.1 0.2 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.3 1.1 2.3 2.7 1.0 2.1 3.1 2.8 2.0 0.4 1.5 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.1 0.3 0.2 1.5 0.5 0.0 0.0 0.0 0.1 0.4 17.6 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.2 0.0 0.2 0.0 0.0 2.2 83.7 0.1 0.0 0.2 0.6 0.0 1.3 0.4 0.2 0.6 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.6 0.3 21.1 135.8 0.3 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.1 0.3 0.3 0.1 0.3 0.4 GNAZ ENSG00000128266 "G protein subunit alpha z" P19086 22 23070519-23125032 "Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.2" "Cell type enhanced" "Detected in many" "Adipocytes: 32.1;Horizontal cells: 124.5;Rod photoreceptor cells: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 18.3;SCLC-21H: 39.0;SH-SY5Y: 24.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003011 Enhanced Approved Vesicles NA NA 180000 "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA003011: AB_1078918" "unprognostic (7.61e-2)" "unprognostic (1.63e-2)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.85e-4)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (1.51e-3)" "unprognostic (3.45e-2)" "unprognostic (1.30e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-3)" "unprognostic (1.68e-2)" "unprognostic (9.69e-2)" "unprognostic (2.29e-1)" "unprognostic (6.63e-2)" "unprognostic (2.82e-1)" "unprognostic (1.30e-1)" 9.2 6.6 30.7 2.8 35.9 1.6 8.4 27.4 36.2 5.4 27.8 14.8 1.7 10.1 2.8 5.0 10.2 11.2 2.4 33.6 24.5 2.0 0.5 1.4 1.8 29.6 30.7 8.9 1.6 7.5 24.1 0.3 32.0 8.5 1.6 33.0 1.8 17.2 1.4 1.4 3.2 11.9 27.0 4.7 11.5 4.3 29.0 0.5 1.5 2.1 1.2 8.0 3.6 35.7 0.1 2.0 6.8 14.3 0.0 0.0 0.4 9.2 18.3 8.9 6.0 0.1 0.1 17.7 0.6 0.8 12.2 0.3 8.4 0.3 6.4 2.2 7.0 1.1 10.2 13.1 0.6 0.0 1.4 0.0 0.3 0.2 0.5 2.2 0.2 1.0 0.2 5.4 0.2 6.4 0.1 0.1 4.1 0.5 5.5 0.1 6.8 2.7 0.1 0.1 39.0 24.0 2.0 4.4 1.9 0.8 1.9 0.2 0.0 7.2 8.2 2.0 0.2 6.6 12.0 9.2 3.7 0.6 2.8 0.9 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.0 2.0 30.7 35.9 27.4 36.2 33.6 24.5 29.6 30.7 32.0 27.0 29.0 35.7 32.1 3.2 0.0 4.9 0.7 0.3 0.3 0.4 0.0 12.6 0.8 1.7 1.6 7.2 0.7 3.7 8.4 0.0 0.7 0.3 0.0 2.0 1.5 1.6 0.5 5.0 4.8 2.7 11.0 1.6 0.0 1.1 1.5 0.4 0.0 2.1 2.2 0.4 0.1 124.5 11.0 0.3 2.0 0.0 1.7 2.1 4.1 18.6 1.8 1.0 1.2 19.3 1.0 2.0 16.5 0.7 0.0 4.1 0.1 0.3 0.1 0.9 1.3 37.7 0.0 9.0 2.1 2.0 4.2 0.0 0.4 0.0 0.6 0.9 0.2 0.1 GNL1 HSR1 ENSG00000204590 "G protein nucleolar 1 (putative)" P36915 6 30541377-30557174 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 193.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033575, HPA043338, HPA050455" Uncertain Supported Vesicles NA NA 11000 "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB033575: AB_2109945, HPA043338: AB_2678437, HPA050455: AB_2681132" "unprognostic (2.76e-2)" "unprognostic (3.68e-2)" "unprognostic (2.21e-1)" "unprognostic (3.53e-2)" "unprognostic (3.30e-2)" "unprognostic (2.75e-1)" "unprognostic (4.22e-2)" "unprognostic (8.33e-2)" "unprognostic (1.03e-1)" "unprognostic (3.84e-2)" "unprognostic (3.95e-3)" "unprognostic (7.32e-2)" "unprognostic (5.67e-3)" "unprognostic (4.42e-2)" "unprognostic (2.10e-1)" "unprognostic (4.15e-1)" "unprognostic (1.78e-1)" 22.6 19.6 3.3 3.5 3.5 2.0 21.7 2.0 4.0 30.5 1.7 19.3 0.6 27.3 3.9 17.0 26.2 2.4 15.2 2.3 4.8 21.2 13.1 27.8 2.3 3.3 3.0 37.5 24.3 7.8 23.8 2.8 3.5 19.9 3.4 4.1 16.6 3.9 15.0 23.3 17.4 4.5 2.7 18.7 20.0 38.0 4.7 5.0 23.3 1.6 4.6 21.1 22.9 5.4 10.5 2.2 5.9 16.9 10.9 12.8 0.4 3.2 6.4 2.6 4.0 15.1 6.5 4.8 6.2 10.4 25.8 6.9 15.4 12.7 4.4 1.8 9.0 7.8 7.9 1.4 0.0 1.3 5.0 11.0 9.9 20.4 6.7 0.0 1.1 18.6 14.2 0.3 6.5 2.4 3.8 0.2 3.4 8.4 1.6 7.3 3.6 5.3 8.7 4.5 5.2 4.9 4.2 3.1 1.6 2.0 3.0 4.9 6.2 10.5 3.0 2.0 3.7 7.9 9.3 9.9 0.1 6.6 13.1 0.2 0.2 0.2 0.7 0.2 1.0 0.4 0.8 0.9 0.0 0.3 0.1 0.3 0.2 0.4 0.2 0.1 0.5 0.5 3.3 3.5 2.0 4.0 2.3 4.8 3.3 3.0 3.5 2.7 4.7 5.4 48.2 44.8 41.8 17.3 45.0 59.3 104.0 44.1 56.3 40.6 35.4 40.6 14.3 34.3 28.8 25.8 41.7 72.6 36.3 22.6 23.5 38.4 113.1 30.0 40.2 50.8 46.0 13.3 26.2 35.3 65.5 46.4 27.5 47.5 31.7 40.9 50.7 16.9 28.5 16.8 27.0 25.8 26.4 19.8 32.5 193.5 36.4 24.6 28.4 9.4 14.8 30.9 18.6 11.1 10.8 29.9 22.1 32.0 42.6 56.2 32.4 30.3 20.7 34.6 39.5 47.9 58.1 108.4 51.8 36.1 40.6 160.1 46.0 40.9 27.0 66.7 GPHA2 "A2, GPA2, MGC126572, ZSIG51" ENSG00000149735 "Glycoprotein hormone subunit alpha 2" Q96T91 11 64934471-64935893 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "pancreas: 360.5" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.5;Exocrine glandular cells: 17.4;Pancreatic endocrine cells: 2.4;Spermatocytes: 7.7;Spermatogonia: 3.2" "Cancer enriched" "Detected in some" 7 "testis cancer: 15.8" "Region enhanced" "Detected in single" "cerebellum: 3.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "Hep G2: 21.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067068 Approved Vesicles "Secreted to blood" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA067068: " "unprognostic (1.13e-1)" "unprognostic (8.31e-3)" "unprognostic (1.51e-2)" "unprognostic (9.22e-4)" "unprognostic (7.88e-3)" "unprognostic (2.62e-1)" "unprognostic (1.45e-1)" "unprognostic (3.20e-2)" "unprognostic (1.82e-1)" "unprognostic (1.75e-1)" "unprognostic (5.03e-2)" "unprognostic (9.86e-3)" "unprognostic (1.70e-1)" 0.0 0.1 0.3 0.2 0.6 0.1 0.1 3.6 0.6 0.1 0.0 0.1 0.1 0.2 0.2 0.0 0.4 16.9 0.0 0.3 0.3 0.8 0.7 0.3 0.6 0.4 0.3 2.7 360.5 0.0 28.0 0.0 0.6 0.7 0.0 0.1 0.3 0.5 0.0 0.5 0.5 0.0 0.2 0.6 1.1 10.8 0.4 0.1 0.3 0.0 0.5 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 21.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 3.6 0.6 0.3 0.3 0.4 0.3 0.6 0.2 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.1 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 17.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 0.0 0.0 7.7 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 GPR137C "DKFZp762F0713, TM7SF1L2" ENSG00000180998 "G protein-coupled receptor 137C" Q8N3F9 14 52552836-52637713 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 14.6;epididymis: 8.1;retina: 17.3" "Group enriched" "Detected in many" 5 "Excitatory neurons: 85.5;Inhibitory neurons: 125.4;Oligodendrocyte precursor cells: 101.6;Oligodendrocytes: 137.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 9 "NK-cells: 1.5;T-cells: 1.4" "Cell line enhanced" "Detected in many" "SH-SY5Y: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003640, HPA030763" Uncertain Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA003640: AB_2667025, HPA030763: AB_10602352" "unprognostic (1.39e-1)" "unprognostic (1.45e-1)" "unprognostic (1.23e-1)" "unprognostic (6.84e-2)" "unprognostic (8.50e-3)" "unprognostic (7.34e-3)" "unprognostic (5.95e-3)" "unprognostic (2.32e-2)" "unprognostic (4.41e-2)" "unprognostic (8.42e-4)" "unprognostic (2.20e-2)" "unprognostic (1.04e-1)" "unprognostic (7.88e-2)" "unprognostic (4.08e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (2.60e-1)" 0.5 0.7 5.3 0.2 3.8 0.9 0.5 14.6 7.2 0.6 0.0 0.4 0.7 0.8 8.1 0.4 0.3 1.1 1.0 4.0 5.5 0.4 0.6 0.8 0.4 5.9 5.9 0.7 0.2 0.4 1.5 0.4 5.0 0.7 0.4 17.3 0.2 0.4 0.5 0.2 0.3 0.4 2.4 1.0 0.4 2.9 8.4 0.3 0.6 0.6 0.1 0.4 0.3 7.7 0.8 0.3 6.6 6.4 1.7 0.6 2.7 3.3 2.2 3.2 7.8 0.9 1.4 0.2 1.9 2.2 6.5 1.5 2.5 0.5 4.5 0.4 1.7 0.3 1.5 0.4 0.1 0.1 1.1 0.4 0.0 2.8 0.2 0.6 1.5 1.1 0.9 2.3 4.4 3.8 0.1 0.6 1.1 0.4 4.1 1.2 4.3 0.3 1.0 4.8 7.4 9.1 1.3 0.2 0.1 2.7 4.4 0.0 0.0 6.8 7.6 5.5 2.3 0.4 1.6 0.8 1.5 0.1 1.9 0.0 0.0 0.0 1.0 0.0 1.4 0.0 0.5 1.4 0.0 0.0 0.3 0.5 0.1 1.5 0.1 0.0 0.5 0.2 5.3 3.8 14.6 7.2 4.0 5.5 5.9 5.9 5.0 2.4 8.4 7.7 2.8 0.0 1.3 20.2 0.7 0.6 0.7 0.1 2.2 22.4 1.4 1.4 2.5 1.5 0.1 0.0 2.1 0.3 0.4 0.4 0.0 0.3 2.3 3.4 1.6 3.8 1.2 0.0 85.5 0.2 0.3 1.9 1.1 6.2 0.0 5.6 2.2 0.5 0.5 6.7 125.4 0.7 0.0 2.2 0.8 1.5 0.6 0.9 1.8 21.5 0.2 5.4 1.0 101.6 137.4 0.0 0.0 0.7 1.0 1.8 0.1 0.2 0.1 20.2 0.0 1.1 1.7 6.9 5.1 1.3 0.9 0.1 1.2 1.2 0.1 0.5 GPR17 ENSG00000144230 "G protein-coupled receptor 17" Q13304 2 127645864-127652639 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 19.8;intestine: 23.8" "Cell type enriched" "Detected in some" 58 "Oligodendrocyte precursor cells: 58.3" "Cancer enriched" "Detected in some" 32 "glioma: 16.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "naive B-cell: 1.9" "Lineage enriched" "Detected in single" 19 "B-cells: 1.9" "Cell line enhanced" "Detected in some" "HeLa: 3.1;REH: 4.4;TIME: 4.3;U-2 OS: 1.7;U-2197: 2.0;U-251 MG: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029766 Enhanced Supported Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA029766: AB_10612114" "unprognostic (8.10e-2)" "unprognostic (1.73e-1)" "unprognostic (2.61e-1)" "unprognostic (1.42e-2)" "unprognostic (1.54e-1)" "unprognostic (5.19e-2)" "unprognostic (2.77e-5)" "unprognostic (8.40e-3)" "unprognostic (2.92e-1)" "unprognostic (3.25e-2)" "unprognostic (1.61e-3)" "unprognostic (6.60e-2)" "unprognostic (2.11e-3)" "unprognostic (3.33e-2)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" 9.8 1.1 9.1 3.4 6.3 0.1 7.9 4.7 9.7 3.6 3.5 23.8 1.5 14.8 1.4 2.4 5.3 2.1 19.8 6.4 5.5 3.0 2.6 9.3 1.1 7.2 7.5 1.8 2.2 0.0 0.7 1.2 7.2 5.5 0.1 0.1 2.0 0.0 7.5 3.4 6.0 0.0 6.4 7.5 5.8 0.9 7.7 0.1 3.8 0.2 0.0 8.8 5.0 8.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.1 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.1 0.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.1 4.4 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 1.2 0.1 0.0 4.3 0.0 1.7 2.0 2.6 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 6.3 4.7 9.7 6.4 5.5 7.2 7.5 7.2 6.4 7.7 8.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 58.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 GPR180 ITR ENSG00000152749 "G protein-coupled receptor 180" Q86V85 13 94601857-94634661 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047250 Approved Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA047250: AB_2679998" "unprognostic (3.91e-3)" "unprognostic (3.28e-1)" "unprognostic (4.16e-3)" "unprognostic (2.95e-1)" "unprognostic (1.17e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-3)" "unprognostic (2.57e-2)" "unprognostic (2.89e-2)" "unprognostic (6.71e-2)" "unprognostic (1.47e-1)" "unprognostic (2.86e-2)" "prognostic unfavorable (3.18e-5)" "unprognostic (2.49e-2)" "unprognostic (1.10e-1)" "unprognostic (8.47e-2)" "unprognostic (2.80e-2)" 5.8 2.3 3.0 2.4 3.6 0.9 2.6 4.5 4.5 2.7 4.1 2.1 2.0 2.4 1.8 1.7 2.5 1.8 1.8 3.4 3.2 2.5 6.9 2.4 2.4 2.8 3.0 2.4 3.1 2.5 3.5 3.6 3.1 2.5 2.5 7.0 2.8 2.3 1.8 1.9 1.6 2.8 3.6 2.2 2.7 1.1 3.2 2.6 3.6 1.8 2.6 2.3 1.5 3.6 14.6 3.6 5.1 5.4 10.5 11.4 2.1 9.7 7.7 9.3 12.3 4.4 9.8 4.8 4.1 8.4 6.4 9.0 7.3 6.9 12.7 12.7 4.6 9.4 4.9 0.0 8.3 13.6 7.3 6.5 5.8 5.7 7.7 8.3 9.6 6.8 2.7 2.3 9.3 2.1 6.9 3.0 3.3 10.4 4.0 7.8 6.8 2.0 10.4 4.3 7.4 5.3 4.5 9.9 12.2 6.4 7.0 5.5 8.7 5.7 4.6 6.8 8.2 3.8 4.2 2.2 9.5 10.9 7.9 0.1 0.5 0.1 0.8 0.3 1.4 0.5 0.9 0.6 0.9 0.5 1.1 0.9 0.0 0.5 0.4 0.6 1.2 0.4 3.0 3.6 4.5 4.5 3.4 3.2 2.8 3.0 3.1 3.6 3.2 3.6 9.0 3.2 4.1 20.2 6.1 6.0 5.4 11.2 7.4 12.5 7.4 5.5 6.8 7.2 7.8 12.9 31.3 8.7 9.3 3.8 5.9 8.3 1.0 11.1 8.9 8.3 10.3 3.6 47.6 10.2 27.8 11.8 9.7 9.0 5.1 9.2 9.7 30.8 10.5 18.5 30.5 9.8 6.1 4.4 4.9 0.7 9.6 5.3 7.2 18.7 4.1 15.4 9.2 40.7 26.3 9.6 3.7 5.7 16.0 10.6 3.0 7.5 16.8 22.0 6.6 6.3 10.6 3.5 10.6 6.4 4.7 4.1 6.6 3.6 5.5 5.0 GRB10 ENSG00000106070 "Growth factor receptor bound protein 10" Q13322 7 50590063-50793462 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 143.0;Late spermatids: 212.6;Oligodendrocytes: 124.7;Rod photoreceptor cells: 81.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 10.0;eosinophil: 3.0" "Lineage enriched" "Detected in single" 28 "granulocytes: 10.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB019423, HPA027502, HPA031818" Enhanced Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 54: Non-specific - Microtubule organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "CAB019423: AB_2112883, HPA027502: AB_10602325, HPA031818: AB_2674057" "unprognostic (2.82e-2)" "unprognostic (1.69e-3)" "unprognostic (1.25e-2)" "unprognostic (1.45e-2)" "unprognostic (3.68e-2)" "unprognostic (1.60e-1)" "unprognostic (6.83e-2)" "unprognostic (5.91e-3)" "unprognostic (1.67e-2)" "unprognostic (2.31e-3)" "unprognostic (4.44e-1)" "unprognostic (2.07e-1)" "unprognostic (1.23e-3)" "unprognostic (1.73e-3)" "unprognostic (8.16e-3)" "unprognostic (2.63e-2)" "unprognostic (8.50e-2)" 27.6 26.0 29.5 6.5 33.6 10.0 25.0 25.2 32.5 18.2 28.5 27.2 17.2 19.8 10.3 9.5 18.8 21.6 34.8 26.5 40.2 29.3 32.1 20.6 6.0 31.5 41.8 14.2 94.3 10.5 24.3 14.7 40.2 20.1 6.4 83.5 16.5 15.0 57.4 9.1 13.3 16.1 21.6 36.8 17.6 18.1 48.2 2.8 27.8 76.0 4.0 31.0 15.9 33.5 0.3 32.5 51.6 21.1 23.5 17.8 27.6 13.1 11.3 24.9 29.7 19.8 0.4 0.7 22.6 16.7 71.0 3.1 53.5 13.9 12.2 0.4 21.6 56.7 32.6 14.4 49.8 36.0 84.1 46.4 21.0 38.6 37.4 23.9 62.7 3.9 109.5 0.6 18.7 4.0 6.4 48.0 56.9 27.2 55.4 16.8 0.0 0.3 16.0 13.1 22.7 0.2 1.6 8.1 68.7 33.0 27.7 71.6 78.7 21.8 29.6 45.4 50.4 2.1 0.7 0.4 68.9 32.2 75.2 10.0 0.1 3.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 29.5 33.6 25.2 32.5 26.5 40.2 31.5 41.8 40.2 21.6 48.2 33.5 46.3 6.4 8.3 3.9 1.2 7.5 5.3 9.4 7.4 12.1 14.8 9.0 13.5 47.1 5.2 5.5 87.6 4.5 0.3 6.9 1.9 18.3 143.0 5.3 12.4 45.2 0.0 19.0 64.8 24.4 16.5 15.4 5.6 9.7 0.0 0.8 53.2 26.8 1.6 5.0 55.0 2.8 6.1 9.7 5.5 212.6 1.8 4.0 7.2 40.3 0.8 21.8 0.0 41.7 124.7 36.4 3.0 0.4 0.6 22.2 11.2 22.2 2.3 81.9 0.0 9.2 10.9 1.9 16.2 1.2 4.3 2.6 1.5 0.9 3.8 7.0 GRM1 "GPRC1A, mGlu1, MGLUR1, PPP1R85" ENSG00000152822 "Glutamate metabotropic receptor 1" Q13255 6 146027646-146437601 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 27.6" "Group enriched" "Detected in some" 6 "Excitatory neurons: 215.5;Inhibitory neurons: 138.8;Rod photoreceptor cells: 124.9" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 27.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015701 Approved Supported Approved Vesicles NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA015701: AB_1853917" "unprognostic (1.04e-2)" "unprognostic (7.33e-2)" "unprognostic (3.73e-3)" "unprognostic (9.77e-3)" "unprognostic (6.75e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-2)" "unprognostic (4.31e-2)" "unprognostic (2.93e-2)" "unprognostic (9.48e-3)" "unprognostic (7.92e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (8.33e-3)" "unprognostic (9.76e-2)" 0.0 0.0 3.3 0.0 3.6 0.0 0.0 27.6 6.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 7.3 2.3 0.7 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 5.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 7.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 3.6 27.6 6.8 7.3 2.3 0.0 3.1 0.9 0.0 7.7 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 3.7 0.0 0.0 1.8 16.7 0.0 0.0 0.0 1.9 0.0 8.5 0.1 0.0 0.2 0.0 0.0 215.5 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.6 6.7 138.8 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 3.7 0.0 4.0 0.0 8.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 124.9 0.0 0.0 0.1 1.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GSAP "LOC54103, PION" ENSG00000186088 "Gamma-secretase activating protein" A4D1B5 7 77310751-77416349 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;NK-cells: 110.2;Oligodendrocyte precursor cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 12.5;U-937: 17.0" "Region enhanced" "Detected in all" "cerebellum: 15.5" "Low region specificity" "Detected in all" HPA023994 Approved Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA023994: AB_1855386" "prognostic favorable (3.36e-4)" "unprognostic (3.70e-1)" "unprognostic (8.55e-3)" "unprognostic (4.53e-3)" "unprognostic (6.80e-3)" "unprognostic (3.52e-3)" "unprognostic (4.36e-2)" "unprognostic (7.18e-3)" "unprognostic (1.09e-1)" "unprognostic (9.98e-3)" "unprognostic (2.07e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (3.61e-1)" "unprognostic (1.82e-2)" "unprognostic (9.49e-2)" "prognostic favorable (4.15e-5)" 5.3 5.3 2.5 10.9 2.2 9.4 5.9 1.8 3.4 3.7 3.2 5.0 2.6 4.0 3.8 3.1 6.4 7.9 4.9 2.4 4.1 6.3 16.4 18.4 13.1 3.6 2.9 3.6 5.4 11.8 7.4 3.8 3.0 5.4 4.7 10.9 4.7 5.1 2.0 4.4 7.5 3.8 2.8 18.7 7.8 1.9 4.2 6.1 8.3 3.9 13.0 5.9 2.3 4.1 3.8 2.0 0.0 0.0 0.5 2.4 0.4 2.3 7.7 1.2 3.2 0.6 5.4 0.8 0.2 0.1 4.3 1.8 0.1 1.9 3.4 2.5 1.6 4.1 0.2 10.7 3.3 0.3 0.0 0.9 7.0 6.2 12.5 9.2 0.5 0.0 0.1 0.3 10.5 2.1 0.0 8.2 0.6 6.0 2.7 0.0 0.2 0.2 6.9 3.2 0.2 5.7 2.5 1.2 6.3 0.5 2.3 3.4 0.0 2.0 1.4 0.2 7.1 1.5 0.1 1.4 8.8 17.0 1.6 0.0 13.3 1.4 8.5 12.7 5.2 18.6 2.8 6.0 16.3 16.4 3.6 6.1 1.7 16.7 9.4 0.4 0.1 8.2 2.5 2.2 1.8 3.4 2.4 4.1 3.6 2.9 3.0 2.8 4.2 4.1 15.2 76.9 60.8 29.0 53.3 5.2 11.6 19.3 13.6 17.0 12.5 9.8 8.5 11.5 22.8 3.7 16.7 3.2 60.5 0.7 25.4 8.5 0.1 10.2 1.6 9.2 5.4 4.4 28.2 6.2 0.7 4.9 9.7 15.8 13.3 9.8 3.3 17.2 9.7 20.2 51.9 6.1 10.2 38.2 23.3 0.2 5.3 46.5 8.8 42.2 30.8 41.6 110.2 72.4 12.7 6.8 4.6 3.8 15.4 20.0 1.4 12.0 9.8 20.9 6.6 9.8 3.2 2.5 1.5 8.6 4.5 1.6 22.8 2.0 4.6 17.2 GTPBP2 ENSG00000172432 "GTP binding protein 2" Q9BX10 6 43605316-43629264 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.4" "Cell line enhanced" "Detected in all" "hTERT-HME1: 181.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031418, HPA031419" Approved Approved Vesicles NA Yes "Cluster 34: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA031418: AB_2673872, HPA031419: AB_10600709" "unprognostic (1.35e-1)" "unprognostic (1.01e-1)" "unprognostic (8.94e-2)" "unprognostic (1.08e-3)" "unprognostic (2.56e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (1.08e-6)" "unprognostic (4.71e-2)" "unprognostic (2.58e-3)" "unprognostic (6.47e-2)" "unprognostic (8.31e-2)" "unprognostic (6.15e-3)" "prognostic unfavorable (1.44e-15)" "unprognostic (1.13e-1)" "unprognostic (3.36e-1)" "unprognostic (1.06e-1)" "unprognostic (2.89e-3)" 38.5 29.8 14.5 15.3 15.3 28.7 37.4 16.5 17.9 39.5 16.0 34.0 19.9 26.8 15.5 61.3 25.1 12.5 35.4 14.4 15.0 36.1 33.3 46.7 16.9 17.5 16.7 29.0 40.0 24.1 40.0 18.0 15.6 31.5 17.0 18.9 42.6 11.6 31.6 26.5 34.7 15.4 14.3 44.5 35.9 27.2 17.0 16.8 44.2 10.4 17.0 33.9 40.4 16.2 59.2 10.9 37.7 24.0 28.3 30.6 45.6 56.3 55.2 52.6 70.1 12.0 19.9 18.8 23.5 26.9 53.8 31.6 9.8 14.5 45.6 60.9 31.6 44.1 33.0 13.9 126.0 35.6 50.1 35.1 160.5 72.5 181.4 35.1 20.5 25.7 77.1 107.8 26.2 13.9 23.4 45.1 10.6 41.2 14.8 19.4 29.5 17.5 24.0 25.8 33.1 32.4 19.5 14.0 72.5 19.0 30.3 37.3 34.8 27.2 33.2 20.5 38.3 70.8 38.2 26.7 45.4 26.0 27.5 5.4 0.8 2.1 1.2 0.7 0.9 0.6 0.2 1.1 0.4 1.0 0.7 1.0 1.3 0.6 0.9 1.1 0.6 1.2 14.5 15.3 16.5 17.9 14.4 15.0 17.5 16.7 15.6 14.3 17.0 16.2 19.6 3.2 5.5 6.8 5.1 5.2 2.3 4.3 1.2 5.9 7.5 5.0 11.4 5.7 5.7 1.8 8.4 2.8 5.3 24.0 0.0 10.1 17.0 8.5 8.2 9.7 1.2 14.3 7.2 10.1 9.8 6.8 11.7 13.3 1.3 5.7 6.8 5.5 8.2 1.7 6.3 8.8 2.0 12.6 6.5 47.6 5.3 16.0 7.2 5.6 10.1 3.4 1.0 5.5 9.1 20.7 13.4 4.1 2.4 5.8 6.8 1.8 4.1 9.2 13.1 5.3 7.8 7.1 8.1 4.4 5.3 2.5 3.8 4.7 6.0 12.6 GUCY2C "GUC2C, STAR" ENSG00000070019 "Guanylate cyclase 2C" P25092 12 14612632-14696599 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "intestine: 68.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 34.4;Enteroendocrine cells: 176.7;Intestinal goblet cells: 56.0;Paneth cells: 97.9;Proximal enterocytes: 81.5;Undifferentiated cells: 47.6" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.9;stomach cancer: 9.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 1.4;CACO-2: 1.1;CAPAN-2: 1.7;SiHa: 1.6" "Region enhanced" "Detected in some" "midbrain: 1.8" "Low region specificity" "Detected in all" "HPA037655, HPA073759" Uncertain Uncertain Vesicles NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA037655: AB_10672388, HPA073759: " "unprognostic (1.08e-1)" "unprognostic (2.12e-1)" "unprognostic (3.58e-2)" "unprognostic (2.11e-2)" "unprognostic (1.60e-2)" "unprognostic (5.67e-3)" "prognostic unfavorable (1.37e-5)" "unprognostic (9.14e-2)" "unprognostic (1.49e-2)" "unprognostic (2.95e-1)" "unprognostic (1.58e-1)" "unprognostic (5.40e-2)" "unprognostic (2.35e-4)" "unprognostic (8.02e-2)" "unprognostic (1.64e-1)" "unprognostic (1.33e-1)" "unprognostic (1.98e-1)" 0.5 0.2 0.1 3.4 0.3 0.5 0.0 0.2 0.1 0.0 3.0 37.2 68.2 0.3 0.0 1.9 0.0 0.9 2.2 0.2 0.3 0.4 0.3 0.2 0.4 0.4 0.3 0.0 2.2 0.0 0.0 0.2 0.4 0.3 41.4 0.1 0.6 0.0 0.7 1.0 66.5 1.4 0.5 0.2 1.9 0.4 0.3 0.0 0.5 0.0 0.3 0.5 0.2 0.5 0.4 0.0 0.0 1.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.1 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.2 1.6 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.3 1.1 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.2 0.1 0.3 0.2 0.1 0.2 0.3 0.4 0.3 0.4 0.5 0.3 0.5 0.0 0.0 0.0 1.3 6.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 34.4 0.0 0.0 0.1 0.1 0.0 0.0 176.7 0.0 1.4 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 56.0 0.0 0.3 0.3 0.2 0.0 0.3 0.0 1.0 0.3 0.0 0.0 1.0 0.2 0.4 97.9 0.0 0.1 0.0 81.5 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 47.6 0.0 GULP1 "CED-6, CED6, GULP" ENSG00000144366 "GULP PTB domain containing engulfment adaptor 1" Q9UBP9 2 188291669-188595931 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid transport, Phagocytosis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 83.0" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 136.5;Inhibitory neurons: 115.5;Muller glia cells: 129.4;Syncytiotrophoblasts: 204.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 106.9;SH-SY5Y: 83.4;WM-115: 228.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020587 Enhanced Approved Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA020587: AB_1850452" "unprognostic (1.95e-1)" "unprognostic (3.32e-1)" "unprognostic (3.80e-2)" "unprognostic (5.19e-2)" "unprognostic (2.12e-2)" "unprognostic (2.41e-1)" "unprognostic (8.69e-4)" "unprognostic (3.86e-2)" "unprognostic (1.06e-1)" "unprognostic (9.28e-2)" "unprognostic (8.25e-3)" "unprognostic (2.23e-1)" "prognostic favorable (4.25e-6)" "prognostic unfavorable (6.17e-4)" "unprognostic (1.29e-1)" "unprognostic (7.33e-2)" "unprognostic (3.04e-4)" 9.4 24.5 2.0 5.8 6.4 0.2 13.1 0.0 4.3 27.7 33.0 13.3 13.5 35.3 83.0 19.2 18.2 17.5 5.2 3.6 7.3 21.3 0.8 13.3 1.7 22.7 4.1 31.8 22.2 26.1 3.4 19.7 23.2 27.7 7.8 17.7 16.1 28.1 9.6 6.2 15.8 21.7 0.3 5.9 22.6 28.0 4.0 1.7 7.8 16.7 3.3 11.9 14.3 0.1 12.5 26.9 106.9 23.8 17.1 15.5 18.6 16.5 27.0 25.1 19.9 18.9 62.6 0.0 13.2 13.2 28.2 8.3 20.0 1.5 18.9 0.0 13.9 27.0 20.5 0.2 15.1 0.0 0.2 10.1 4.2 13.0 14.2 42.9 12.7 0.0 22.5 0.5 19.3 1.8 0.0 0.4 27.4 18.1 46.0 0.1 25.1 14.0 60.0 4.7 0.5 83.4 0.0 14.6 40.2 47.9 4.7 0.1 5.9 7.8 3.8 26.3 9.6 0.0 0.1 0.0 4.6 0.0 228.6 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.0 6.4 0.0 4.3 3.6 7.3 22.7 4.1 23.2 0.3 4.0 0.1 22.8 16.0 13.4 43.4 1.6 15.7 23.9 3.6 10.2 1.5 10.6 12.2 1.6 45.8 28.2 23.9 0.0 41.1 0.6 3.7 45.0 33.0 5.0 23.9 35.4 32.1 136.5 0.0 82.7 38.2 5.9 55.3 39.8 52.1 0.0 2.2 10.0 1.5 3.2 1.7 115.5 4.6 14.2 1.0 10.5 7.9 20.5 2.0 35.6 53.4 1.1 129.4 0.0 3.0 3.1 51.3 9.8 61.3 1.4 79.8 30.8 43.2 43.5 3.7 6.6 42.2 27.9 79.6 23.9 38.9 27.6 204.4 2.7 27.0 4.7 34.5 GUSB ENSG00000169919 "Glucuronidase beta" P08236 7 65960684-65982215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 213.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036322, HPA036323" Approved Supported Vesicles "Intracellular and membrane" NA NA 330000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA036322: AB_10670796, HPA036323: AB_2675059" "unprognostic (1.54e-2)" "unprognostic (6.49e-2)" "unprognostic (1.18e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.89e-1)" "unprognostic (1.56e-3)" "unprognostic (1.32e-1)" "unprognostic (2.32e-1)" "unprognostic (7.00e-3)" "unprognostic (1.91e-1)" "unprognostic (3.34e-2)" "unprognostic (8.83e-3)" "unprognostic (1.98e-1)" "unprognostic (5.06e-1)" "unprognostic (1.45e-1)" 28.4 18.2 11.0 22.3 12.3 84.2 80.9 12.0 16.1 26.7 14.3 38.2 36.1 26.2 41.8 16.4 24.6 27.6 19.6 10.7 11.5 25.1 104.0 35.7 25.6 13.2 12.2 19.9 33.6 30.3 12.6 48.2 13.2 20.2 41.9 9.7 32.9 21.2 10.9 18.8 29.8 19.1 11.9 34.0 38.1 19.5 13.0 22.7 27.7 14.4 24.0 27.3 15.4 13.5 67.0 26.5 25.2 56.3 80.9 49.1 35.3 21.3 56.8 45.0 42.1 37.0 67.8 30.9 32.3 26.8 24.1 27.5 16.5 25.1 26.8 27.3 34.1 41.5 40.9 27.3 39.7 89.6 67.1 33.4 26.7 26.3 33.3 54.5 39.3 18.0 63.2 213.5 30.5 50.3 34.2 92.0 17.9 103.0 21.0 34.4 55.9 172.4 29.4 42.8 36.2 32.7 55.6 129.1 72.3 29.9 71.1 88.8 28.5 55.3 49.3 21.8 53.6 119.6 151.9 50.0 41.0 116.3 68.3 26.0 80.1 65.7 32.0 103.0 28.4 27.7 24.7 28.4 80.5 22.6 16.8 19.5 13.2 46.6 93.5 34.2 34.5 51.4 11.0 12.3 12.0 16.1 10.7 11.5 13.2 12.2 13.2 11.9 13.0 13.5 53.1 51.3 58.7 10.1 33.0 18.0 32.0 51.9 29.0 12.2 26.1 19.9 12.2 48.6 48.9 29.5 8.4 81.9 32.6 52.2 5.9 41.1 59.1 28.9 26.5 39.7 43.0 47.1 12.3 30.3 61.2 49.5 49.5 49.4 36.8 38.3 37.9 72.7 126.4 16.8 10.6 51.6 30.5 88.1 33.2 46.7 43.2 78.0 39.2 14.0 44.8 28.0 20.6 8.5 14.2 29.4 49.5 28.6 87.5 25.3 50.6 26.8 43.2 20.1 26.3 27.1 26.0 49.6 31.0 16.0 14.8 66.9 32.2 24.4 44.3 29.6 GYG1 GYG ENSG00000163754 "Glycogenin 1" P46976 3 148991408-149031775 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 560.0;tongue: 357.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 229.8;Early spermatids: 251.2;Late spermatids: 368.8;Spermatocytes: 296.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030497, HPA073229" Supported Approved Vesicles NA NA 30000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA030497: AB_10602326, HPA073229: " "unprognostic (2.68e-2)" "unprognostic (6.31e-3)" "unprognostic (3.21e-1)" "unprognostic (1.81e-1)" "unprognostic (6.19e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (6.15e-5)" "unprognostic (2.55e-2)" "unprognostic (2.71e-1)" "unprognostic (1.10e-1)" "unprognostic (7.75e-3)" "unprognostic (1.29e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (4.79e-2)" 40.3 31.1 30.1 31.3 32.2 219.8 33.8 33.1 39.4 36.5 28.7 152.2 16.7 64.1 38.7 53.6 52.6 23.9 117.8 29.9 44.0 29.0 18.6 41.1 24.8 37.0 39.7 43.8 42.7 25.2 31.5 23.0 39.0 47.3 25.6 34.3 39.7 64.4 560.0 21.2 37.7 68.1 35.9 59.2 50.7 115.1 33.6 18.0 21.1 357.6 23.0 86.1 30.8 38.3 62.7 39.8 29.0 32.6 78.5 81.7 39.5 90.2 74.4 128.3 119.2 52.3 62.2 0.1 43.5 105.1 68.4 18.8 76.7 39.8 128.6 21.1 33.3 47.6 16.7 59.9 70.7 49.1 68.8 45.1 63.8 42.7 53.3 66.8 74.7 30.7 29.8 109.8 74.7 110.3 9.6 38.9 34.9 48.3 32.2 26.7 43.8 89.3 35.7 57.6 23.7 11.3 47.6 64.6 54.4 27.3 64.4 51.4 62.9 65.4 19.4 47.4 66.9 98.7 59.1 44.4 55.1 74.3 21.7 22.7 58.1 42.4 39.4 59.6 73.1 15.9 25.7 41.3 64.0 14.0 13.8 23.5 27.0 44.3 67.9 25.3 39.4 50.1 30.1 32.2 33.1 39.4 29.9 44.0 37.0 39.7 39.0 35.9 33.6 38.3 27.7 12.8 11.1 16.3 28.3 12.1 22.4 27.7 12.5 9.4 22.5 17.1 229.8 15.7 21.9 33.1 18.8 36.5 50.4 9.9 27.4 43.4 251.2 7.9 15.2 32.6 14.4 12.2 9.8 77.6 47.2 45.0 17.3 9.5 18.3 19.7 45.3 13.5 95.3 6.7 11.3 19.0 26.4 87.1 26.3 368.8 53.1 56.2 40.9 6.5 56.2 132.1 36.0 11.6 5.4 31.6 14.3 76.8 104.1 45.9 15.0 17.3 16.1 7.0 65.7 35.8 50.3 296.7 52.2 23.1 14.9 29.3 61.2 33.8 15.2 19.6 HAPLN1 CRTL1 ENSG00000145681 "Hyaluronan and proteoglycan link protein 1" P10915 5 83637805-83720855 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "placenta: 75.0" "Cell type enhanced" "Detected in some" "Fibroblasts: 146.7;Granulosa cells: 43.2;Inhibitory neurons: 35.6;Syncytiotrophoblasts: 23.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "PC-3: 152.4;SuSa: 70.1;TIME: 91.8;U-2 OS: 139.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019105, HPA019482, HPA025238" Enhanced Approved Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA019105: AB_1850496, HPA019482: AB_1850498, HPA025238: " "unprognostic (5.74e-4)" "unprognostic (2.94e-2)" "unprognostic (6.58e-3)" "unprognostic (2.30e-2)" "unprognostic (1.30e-1)" "unprognostic (2.76e-3)" "unprognostic (6.01e-4)" "unprognostic (2.52e-2)" "unprognostic (1.70e-1)" "unprognostic (9.04e-3)" "unprognostic (1.31e-1)" "unprognostic (2.28e-2)" "prognostic unfavorable (4.81e-9)" "unprognostic (6.87e-2)" "unprognostic (2.04e-1)" "unprognostic (8.62e-2)" "unprognostic (3.91e-2)" 0.1 0.0 0.3 0.8 0.7 0.0 0.1 1.1 0.9 0.1 0.0 9.0 7.2 0.6 0.3 2.1 0.0 0.8 3.9 0.6 2.7 0.1 0.0 0.5 0.0 0.9 1.0 0.5 0.5 0.2 0.0 75.0 0.6 0.9 11.1 0.1 0.5 0.0 0.0 0.3 10.8 0.5 0.3 0.2 4.8 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 2.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.2 0.0 3.4 0.0 152.4 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 70.1 0.1 0.0 91.8 0.0 139.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 1.1 0.9 0.6 2.7 0.9 1.0 0.6 0.3 0.0 0.3 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 9.2 0.0 0.2 0.0 0.0 0.0 0.1 0.5 6.9 0.0 0.0 0.5 0.0 10.6 146.7 0.0 0.1 0.0 43.2 0.0 0.0 10.6 0.0 35.6 2.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 23.7 0.1 3.8 0.4 0.0 HAVCR1 "CD365, HAVCR, HAVCR-1, KIM1, TIM-1, TIM1, TIMD1" ENSG00000113249 "Hepatitis A virus cellular receptor 1" Q96D42 5 157029413-157059119 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 4.6;kidney: 7.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.9;Inhibitory neurons: 1.3;Microglial cells: 5.6;Oligodendrocytes: 1.8;Proximal tubular cells: 2.3" "Cancer enriched" "Detected in many" 12 "renal cancer: 26.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 93.0;CACO-2: 113.9;RPTEC TERT1: 43.5" "Low region specificity" "Detected in many" "HPA007173, CAB075697" Uncertain Approved Vesicles NA NA 155000 "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "CAB075697: , HPA007173: AB_1080282" "unprognostic (1.24e-1)" "unprognostic (1.66e-1)" "unprognostic (5.76e-2)" "unprognostic (2.00e-1)" "unprognostic (6.99e-2)" "unprognostic (2.46e-3)" "unprognostic (4.75e-3)" "unprognostic (3.20e-2)" "unprognostic (3.21e-1)" "unprognostic (8.70e-4)" "unprognostic (3.81e-3)" "unprognostic (7.10e-3)" "prognostic unfavorable (7.81e-4)" "unprognostic (1.38e-1)" "unprognostic (1.57e-1)" "prognostic favorable (1.32e-4)" 0.3 0.0 0.3 0.4 0.3 0.9 0.1 0.6 0.4 0.1 0.5 4.6 0.2 0.1 0.2 0.0 0.1 0.5 0.0 0.4 0.3 7.5 0.3 0.3 0.6 0.7 0.4 0.1 0.0 0.1 0.0 0.1 0.5 0.0 3.5 0.3 0.1 0.0 0.0 0.2 0.1 0.2 0.3 0.3 0.3 0.9 0.5 0.1 0.1 0.0 0.3 0.1 0.0 0.8 0.0 93.0 0.2 0.0 0.3 0.0 13.8 0.0 0.0 0.0 0.0 113.9 0.0 0.0 14.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 4.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 43.5 3.4 0.2 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 5.6 0.1 0.0 0.0 0.0 0.5 0.2 0.1 0.1 0.1 0.2 0.2 0.3 0.1 0.1 0.2 0.6 0.5 0.2 0.4 0.1 0.1 0.6 0.4 0.3 0.3 0.6 0.4 0.4 0.3 0.7 0.4 0.5 0.3 0.5 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.2 1.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.9 0.0 0.1 0.0 5.6 0.0 0.0 0.0 1.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.1 0.0 HDHD2 DKFZP564D1378 ENSG00000167220 "Haloacid dehalogenase like hydrolase domain containing 2" Q9H0R4 18 47107408-47150500 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040697, CAB045978, HPA059818" Approved Approved Vesicles NA NA 240000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB045978: AB_11124418, HPA040697: AB_2677084, HPA059818: AB_2684132" "unprognostic (3.22e-1)" "unprognostic (6.32e-2)" "unprognostic (9.95e-2)" "unprognostic (7.24e-2)" "unprognostic (1.11e-1)" "unprognostic (1.58e-1)" "unprognostic (3.11e-1)" "unprognostic (1.24e-1)" "unprognostic (2.10e-2)" "unprognostic (5.35e-3)" "unprognostic (1.82e-2)" "unprognostic (8.64e-3)" "prognostic favorable (3.52e-5)" "unprognostic (1.95e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (1.17e-1)" 13.7 26.3 29.1 10.5 31.0 10.5 17.0 37.2 33.4 10.9 27.3 17.2 13.4 11.8 16.0 14.3 16.2 11.9 27.2 28.3 31.5 23.9 30.2 13.5 19.6 34.2 31.8 14.2 17.9 27.0 15.6 11.6 35.2 17.6 16.5 22.1 14.0 17.1 15.5 11.7 13.7 13.5 31.2 13.5 15.8 11.4 31.9 28.1 26.4 24.1 21.2 13.1 10.0 37.5 14.1 9.1 34.5 16.9 20.6 28.4 9.6 15.8 15.3 24.9 25.0 4.7 11.1 23.0 13.4 17.7 11.3 12.2 19.0 21.2 35.3 19.2 17.6 22.1 15.0 23.5 28.2 31.1 19.6 23.4 25.5 14.0 31.3 27.1 21.0 37.2 22.8 26.3 32.6 19.0 29.2 19.6 33.9 11.9 9.3 28.1 22.0 31.2 31.4 21.5 31.2 26.0 15.0 10.6 19.5 23.7 16.0 42.7 15.2 18.9 15.2 5.4 11.5 33.1 16.9 19.9 23.3 32.1 18.8 21.4 24.7 19.7 20.7 22.9 21.8 27.3 21.5 20.5 23.9 26.7 27.1 21.6 2.3 30.5 23.3 15.8 24.2 21.4 29.1 31.0 37.2 33.4 28.3 31.5 34.2 31.8 35.2 31.2 31.9 37.5 8.8 16.0 18.2 21.5 16.9 7.1 11.1 10.7 13.6 22.5 17.7 10.5 13.1 15.7 14.0 11.0 14.6 25.0 9.7 15.6 72.4 18.9 1.9 11.0 8.5 11.5 13.8 13.9 28.9 17.9 15.0 11.0 12.8 6.4 7.6 15.6 13.9 28.1 21.7 45.4 29.2 16.2 14.2 20.3 15.0 2.7 17.7 15.0 16.0 20.6 22.7 53.1 14.4 36.7 45.4 16.4 19.3 23.7 9.7 17.5 16.0 57.7 16.4 27.0 19.7 15.1 19.7 20.2 35.1 13.1 6.0 19.7 12.2 29.8 21.6 13.0 HEPACAM "FLJ25530, GLIALCAM" ENSG00000165478 "Hepatic and glial cell adhesion molecule" Q14CZ8 11 124919205-124936412 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Cell cycle, Growth arrest, Growth regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 222.6;choroid plexus: 79.7" "Group enriched" "Detected in some" 9 "Astrocytes: 184.8;Oligodendrocyte precursor cells: 72.9;Oligodendrocytes: 163.2" "Cancer enriched" "Detected in some" 12 "glioma: 29.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 30 "Hep G2: 25.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017613, CAB025486" Enhanced Approved Vesicles NA NA "Cluster 42: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "CAB025486: , HPA017613: AB_1850595" "unprognostic (3.22e-3)" "unprognostic (1.06e-2)" "unprognostic (1.64e-1)" "unprognostic (6.41e-2)" "unprognostic (1.47e-1)" "unprognostic (9.16e-2)" "unprognostic (2.25e-1)" "unprognostic (7.58e-2)" "unprognostic (1.33e-2)" "unprognostic (1.06e-6)" "unprognostic (2.62e-1)" "unprognostic (3.21e-1)" 15.6 0.3 172.8 0.2 203.3 0.0 2.5 170.4 162.1 0.2 79.7 0.4 0.1 0.1 0.1 0.1 0.0 0.1 0.2 163.2 156.1 0.1 16.2 0.0 0.2 222.6 182.8 0.0 0.0 0.0 0.8 0.0 183.6 0.2 0.2 1.8 0.2 0.5 0.1 0.0 0.2 0.1 205.7 0.0 0.1 0.2 182.0 0.0 0.0 0.3 0.6 0.0 0.1 212.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.2 172.8 203.3 170.4 162.1 163.2 156.1 222.6 182.8 183.6 205.7 182.0 212.2 0.1 0.0 0.0 184.8 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 11.2 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.6 0.0 15.5 0.0 72.9 163.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 HIP1 ILWEQ ENSG00000127946 "Huntingtin interacting protein 1" O00291 7 75533298-75738962 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Apoptosis, Differentiation, Endocytosis, Transcription, Transcription regulation" "Actin-binding, Activator" "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1373.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 9.5;eosinophil: 6.8;neutrophil: 6.8;NK-cell: 3.0;plasmacytoid DC: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013606, CAB015334, CAB016402, HPA017964" Enhanced Supported Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB015334: AB_2117565, CAB016402: AB_627725, HPA013606: AB_1850717, HPA017964: AB_1850719" "unprognostic (8.23e-2)" "unprognostic (1.22e-1)" "unprognostic (2.20e-2)" "unprognostic (1.64e-1)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "unprognostic (2.73e-3)" "unprognostic (1.03e-2)" "unprognostic (1.11e-2)" "unprognostic (2.02e-2)" "unprognostic (2.70e-2)" "unprognostic (7.98e-2)" "unprognostic (1.73e-3)" "unprognostic (9.67e-2)" "unprognostic (1.75e-1)" "unprognostic (1.00e-2)" "unprognostic (1.09e-1)" 16.7 7.9 23.6 7.3 38.7 5.4 13.2 29.8 29.0 11.7 14.4 6.1 2.7 9.8 9.2 5.3 12.9 8.3 9.0 22.4 24.9 14.8 9.3 18.5 4.7 34.6 35.4 8.0 3.8 4.2 3.4 19.7 32.0 6.8 4.1 4.6 4.0 11.2 4.2 10.6 5.0 12.2 24.5 11.2 4.8 30.4 34.8 3.1 15.3 8.4 4.5 9.0 7.9 50.9 5.2 55.9 37.1 35.2 15.3 20.8 11.1 9.7 6.3 6.2 4.6 3.2 5.0 3.8 11.2 24.2 21.6 6.3 38.1 8.0 8.3 3.1 7.1 3.0 6.6 5.3 15.2 0.8 14.8 16.0 4.8 20.4 4.2 11.4 26.3 4.2 4.0 3.6 10.1 21.6 2.5 22.2 40.5 0.5 6.6 4.4 15.5 0.3 4.7 20.0 1.8 16.2 9.0 5.6 12.5 32.8 34.6 13.9 9.4 18.0 13.7 6.2 13.6 4.0 0.4 8.9 18.1 8.0 12.4 9.5 0.9 6.8 0.9 0.9 0.7 0.3 0.1 0.7 1.4 0.4 0.1 0.5 6.8 3.0 0.7 3.3 1.4 0.3 23.6 38.7 29.8 29.0 22.4 24.9 34.6 35.4 32.0 24.5 34.8 50.9 54.0 60.9 37.5 43.8 7.8 17.6 6.2 7.1 20.5 12.0 14.8 10.7 14.3 11.5 12.2 27.6 12.5 2.1 27.2 2.2 13.7 14.4 256.9 15.5 24.2 54.3 4.8 7.8 16.3 6.0 10.0 17.1 6.1 25.5 14.0 25.9 36.8 22.5 14.9 23.5 19.0 3.0 6.1 18.5 49.1 1373.3 22.4 24.1 10.6 45.9 9.4 14.3 21.6 336.3 313.7 3.1 7.7 24.8 18.4 4.2 0.3 2.6 1.3 9.4 85.5 25.9 44.8 12.1 5.6 5.6 9.1 0.8 13.5 7.7 3.3 3.5 HLA-DMA "D6S222E, RING6" ENSG00000204257 "Major histocompatibility complex, class II, DM alpha" P28067 6 32948613-32969094 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 120.4" "Cell type enhanced" "Detected in many" "B-cells: 400.4;Hofbauer cells: 354.3;Kupffer cells: 411.6;Langerhans cells: 1350.5;Macrophages: 591.4;monocytes: 332.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 3.8;intermediate monocyte: 3.8;memory B-cell: 6.3;myeloid DC: 7.2;naive B-cell: 6.4;plasmacytoid DC: 5.2" "Group enriched" "Detected in many" 12 "B-cells: 6.4;dendritic cells: 7.2;monocytes: 3.8" "Group enriched" "Detected in some" 5 "U-266/70: 30.5;U-698: 94.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012750, HPA017295" Enhanced Approved Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA012750: AB_1853926, HPA017295: AB_2669575" "unprognostic (1.69e-3)" "unprognostic (3.52e-2)" "unprognostic (8.03e-2)" "prognostic favorable (4.64e-5)" "unprognostic (3.99e-1)" "unprognostic (3.90e-2)" "unprognostic (1.60e-1)" "prognostic favorable (4.59e-4)" "unprognostic (7.01e-2)" "unprognostic (9.69e-2)" "unprognostic (6.66e-2)" "unprognostic (1.89e-1)" "unprognostic (2.12e-3)" "unprognostic (1.41e-1)" "unprognostic (4.95e-2)" "unprognostic (3.80e-1)" "unprognostic (2.14e-2)" 79.9 63.6 0.1 1.0 0.1 23.4 63.4 0.1 0.6 33.1 0.5 26.7 1.6 19.8 22.8 16.0 31.4 0.9 23.5 0.1 0.2 48.0 15.1 98.3 2.4 0.3 0.2 13.5 19.4 0.1 15.6 0.9 0.2 23.1 13.6 0.4 25.9 0.3 11.8 25.1 69.6 0.5 0.3 120.4 32.7 4.0 0.2 0.6 33.1 0.2 36.9 21.3 20.8 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 2.1 0.1 0.1 0.0 0.1 0.0 0.5 1.9 0.0 0.0 0.5 0.3 0.3 2.5 0.4 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.0 0.7 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 30.5 13.7 94.3 0.6 0.0 0.0 0.0 3.8 0.3 0.2 3.8 0.0 6.3 0.1 0.2 7.2 6.4 0.0 0.1 0.4 0.3 1.2 5.2 0.4 3.6 0.1 0.1 0.1 0.6 0.1 0.2 0.3 0.2 0.2 0.3 0.2 0.5 240.5 73.7 171.3 0.7 400.4 48.3 15.5 77.3 17.6 1.8 38.2 32.0 5.2 45.8 95.9 53.3 2.1 4.9 175.6 19.3 17.6 101.0 3.4 12.5 3.1 123.6 3.0 30.5 0.8 51.1 4.2 16.4 43.8 24.5 41.2 8.2 37.1 4.4 354.3 0.0 1.2 25.0 22.4 411.6 1350.5 5.3 16.1 591.4 80.0 14.0 332.4 4.3 33.0 1.5 1.3 26.6 46.2 18.8 68.9 19.1 267.0 47.1 77.6 1.3 19.7 5.4 15.6 4.1 4.8 7.0 41.9 4.0 44.7 4.3 42.6 60.9 HLA-DMB "D6S221E, RING7" ENSG00000242574 "Major histocompatibility complex, class II, DM beta" P28068 6 32934629-32941028 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 78.8;lymphoid tissue: 101.5" "Group enriched" "Detected in many" 4 "B-cells: 228.5;dendritic cells: 129.4;Hofbauer cells: 274.8;Kupffer cells: 201.9;Langerhans cells: 472.8;Macrophages: 272.4;monocytes: 187.1;Proximal enterocytes: 284.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 128.8;dendritic cells: 85.3;monocytes: 73.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 14.2;Daudi: 27.6;EFO-21: 12.4;U-266/70: 7.8;U-698: 31.9" "Low region specificity" "Detected in all" "HPA012298, HPA077524" Supported Supported Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA012298: AB_1853927, HPA077524: " "unprognostic (5.34e-2)" "unprognostic (1.63e-2)" "unprognostic (2.45e-2)" "prognostic favorable (3.89e-5)" "unprognostic (3.07e-1)" "unprognostic (7.64e-3)" "unprognostic (4.00e-1)" "unprognostic (3.46e-3)" "unprognostic (6.99e-2)" "unprognostic (8.76e-2)" "unprognostic (8.93e-2)" "unprognostic (2.73e-1)" "unprognostic (6.82e-3)" "unprognostic (2.03e-1)" "unprognostic (4.14e-2)" "unprognostic (8.35e-2)" "unprognostic (5.60e-2)" 38.3 35.9 0.1 13.2 0.2 6.9 25.7 0.3 1.0 21.6 0.1 19.9 0.0 14.6 7.4 9.3 14.6 0.1 11.1 0.0 0.6 41.9 7.8 59.9 17.6 0.3 0.4 9.5 9.1 0.0 9.2 0.8 0.2 13.1 14.9 0.5 14.7 0.0 5.3 14.3 78.8 0.0 0.9 101.5 17.6 2.2 0.1 9.9 45.9 0.0 18.8 14.4 10.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 27.6 12.4 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 7.8 0.4 31.9 0.0 0.1 0.0 0.5 73.2 16.7 1.2 73.8 2.6 94.0 1.0 2.9 85.0 128.8 0.7 2.4 4.7 16.2 28.1 85.3 6.7 71.4 0.1 0.2 0.3 1.0 0.0 0.6 0.3 0.4 0.2 0.9 0.1 1.1 36.8 9.6 57.0 0.7 228.5 12.0 1.0 5.4 2.2 0.2 2.5 4.7 2.6 5.7 12.7 16.5 0.0 1.7 129.4 3.3 11.7 28.8 0.5 7.5 5.4 37.2 4.2 10.3 0.8 4.4 1.6 3.8 3.1 38.5 15.2 22.7 5.7 0.5 274.8 0.0 0.6 8.5 2.0 201.9 472.8 1.5 3.4 272.4 16.0 27.2 187.1 0.5 21.6 1.0 0.1 2.5 17.8 1.9 3.8 1.3 284.8 7.4 16.8 1.1 6.6 1.6 3.1 0.6 0.7 1.1 10.9 2.7 17.6 0.9 10.3 8.7 HLA-DPA1 HLA-DP1A ENSG00000231389 "Major histocompatibility complex, class II, DP alpha 1" P20036 6 33064569-33080775 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 319.9;lymphoid tissue: 359.6" "Cell type enhanced" "Detected in many" "B-cells: 1387.3;Kupffer cells: 1794.6;Langerhans cells: 8122.8;Macrophages: 2736.9;monocytes: 2940.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 81.8;intermediate monocyte: 187.4;memory B-cell: 150.4;myeloid DC: 296.0;naive B-cell: 136.5;non-classical monocyte: 124.1;plasmacytoid DC: 82.6" "Group enriched" "Detected in all" 7 "B-cells: 150.4;dendritic cells: 296.0;monocytes: 187.4" "Cell line enhanced" "Detected in many" "Daudi: 37.2;HDLM-2: 115.9;REH: 30.3;U-698: 26.1" HPA017967 Enhanced Supported Vesicles NA NA 240000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA017967: AB_1853929" "unprognostic (8.93e-3)" "unprognostic (3.15e-2)" "unprognostic (3.64e-2)" "unprognostic (9.40e-3)" "unprognostic (9.07e-2)" "unprognostic (2.80e-2)" "unprognostic (5.69e-2)" "unprognostic (1.82e-2)" "unprognostic (7.28e-2)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (1.80e-1)" "unprognostic (8.38e-2)" "unprognostic (1.17e-1)" "unprognostic (4.69e-2)" "unprognostic (8.11e-2)" "unprognostic (1.06e-1)" 180.8 108.0 2.2 33.4 2.0 12.8 138.4 2.7 3.3 76.7 2.5 72.1 20.2 55.3 8.3 43.1 63.0 13.0 62.0 2.0 3.4 99.0 36.8 319.9 51.3 4.9 2.8 24.9 28.6 5.9 58.0 3.4 4.3 64.0 16.1 2.0 59.5 16.2 29.5 66.3 174.4 14.6 4.3 359.6 52.1 13.4 3.1 30.2 76.6 7.3 51.5 58.6 60.0 4.4 0.1 0.0 0.0 0.0 0.8 1.3 1.1 0.4 0.4 0.5 0.0 0.0 4.9 37.2 5.0 0.9 7.1 0.0 0.0 0.0 0.1 115.9 2.5 6.2 0.0 0.0 0.1 0.0 11.6 1.7 0.0 2.2 0.0 0.0 0.6 0.0 0.0 3.3 0.0 0.0 0.1 0.1 0.6 0.0 0.0 30.3 0.0 4.9 0.1 0.0 0.1 0.0 0.0 0.0 2.9 0.0 0.0 1.3 2.6 7.8 0.1 0.1 0.0 5.6 0.9 26.1 12.2 0.2 4.4 2.2 81.8 6.6 21.6 187.4 5.7 150.4 9.6 23.9 296.0 136.5 3.4 15.7 3.0 20.9 124.1 82.6 29.2 136.0 2.2 2.0 2.7 3.3 2.0 3.4 4.9 2.8 4.3 4.3 3.1 4.4 621.8 83.3 404.3 0.3 1387.3 206.7 7.2 12.4 9.1 2.8 41.2 110.4 12.1 64.3 107.3 23.9 0.0 4.2 574.9 10.6 9.8 36.4 2.8 1.2 4.1 337.8 10.2 80.3 0.5 18.8 9.3 53.7 48.4 2.8 64.6 14.3 62.2 7.5 1153.8 5.0 0.9 18.2 12.2 1794.6 8122.8 11.7 18.0 2736.9 302.4 32.8 2940.3 5.1 94.7 0.0 0.1 4.7 5.4 27.4 100.2 10.6 114.0 42.7 129.2 5.0 52.6 14.7 29.8 1.3 4.8 6.0 175.2 6.8 157.8 11.5 28.6 34.4 HLA-E ENSG00000204592 "Major histocompatibility complex, class I, E" P13747 6 30489509-30494194 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2347.3;Hepatic stellate cells: 1647.8;NK-cells: 1874.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 109.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 212.3;U-266/70: 284.8" "CAB024589, HPA031454" Enhanced Approved Vesicles "Secreted to blood" NA NA 100000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB024589: AB_324025, HPA031454: AB_2673891" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (9.20e-2)" "unprognostic (2.47e-3)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.14e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (1.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (2.90e-1)" "unprognostic (4.14e-2)" "unprognostic (1.75e-3)" "unprognostic (1.42e-3)" 724.7 217.2 9.6 173.7 10.0 410.3 578.9 10.9 109.5 360.1 7.3 329.4 0.6 313.5 119.3 330.9 336.5 186.1 356.0 7.7 13.1 375.2 332.8 1144.6 336.3 16.6 22.7 213.2 156.6 95.8 121.8 117.3 16.1 251.2 116.8 12.4 252.5 93.0 179.2 518.3 428.9 89.0 10.0 1007.2 259.5 41.1 11.7 86.0 381.9 0.0 137.5 295.0 366.3 14.2 100.7 16.7 6.8 57.0 212.3 166.4 0.9 0.0 0.0 0.1 0.3 40.0 189.1 65.6 98.7 92.7 148.3 121.6 12.8 53.1 0.0 67.6 32.7 78.6 18.7 0.0 0.0 0.2 38.3 135.4 94.4 67.7 0.0 0.0 0.2 34.6 9.8 0.9 54.5 0.2 0.3 0.8 0.5 32.0 0.0 20.6 0.2 97.4 82.7 58.4 0.3 4.8 63.3 56.9 0.3 1.2 0.0 132.7 102.0 60.7 0.1 0.5 14.7 284.8 171.6 29.4 0.3 62.1 149.2 1140.0 335.4 1153.0 723.3 550.2 602.2 449.1 539.9 709.2 158.5 450.3 531.5 547.8 1916.1 512.9 648.0 138.3 611.7 1441.6 9.6 10.0 10.9 109.5 7.7 13.1 16.6 22.7 16.1 10.0 11.7 14.2 2347.3 310.9 411.0 8.1 950.6 484.6 386.6 284.2 183.8 2.7 238.7 204.0 108.3 231.6 270.0 123.2 6.2 88.2 1304.6 603.0 17.6 484.9 5.0 157.7 157.9 1554.7 216.2 172.3 0.1 677.2 277.0 402.8 233.4 325.6 531.6 59.2 1647.8 120.1 700.6 5.0 0.1 545.3 248.2 1220.4 512.2 11.0 132.0 821.6 466.0 105.9 740.5 100.2 1874.4 2.0 0.5 682.2 559.1 76.3 716.6 436.9 473.9 79.9 214.7 9.5 177.5 535.1 350.1 10.6 7.0 170.0 426.5 359.0 1162.1 196.5 285.0 544.4 HMCN2 "DKFZp434P0216, FLJ23816" ENSG00000148357 "Hemicentin 2" Q8NDA2 9 130265882-130434123 "Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 33.9;intestine: 51.1" "Cell type enriched" "Detected in many" 8 "Skeletal myocytes: 283.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "pons: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 7.8;RH-30: 18.0;SCLC-21H: 2.6;SH-SY5Y: 4.1;U-138 MG: 2.9;U-87 MG: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053903, HPA070647" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 27000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA053903: AB_2682301, HPA070647: AB_2686290" "unprognostic (1.61e-1)" "unprognostic (8.05e-3)" "unprognostic (1.69e-1)" "unprognostic (5.53e-4)" "unprognostic (1.05e-1)" "unprognostic (1.12e-2)" "unprognostic (1.10e-1)" "unprognostic (8.78e-3)" "unprognostic (3.23e-1)" "unprognostic (3.97e-4)" "unprognostic (3.36e-2)" "unprognostic (3.93e-1)" "unprognostic (1.04e-3)" "unprognostic (1.53e-2)" "unprognostic (3.62e-2)" "unprognostic (8.96e-3)" "unprognostic (8.63e-2)" 14.4 1.3 0.3 1.5 0.2 0.0 3.9 0.1 0.7 21.4 0.0 51.1 5.2 33.9 0.1 4.8 10.1 0.7 12.4 0.1 0.9 4.0 1.2 3.8 1.2 2.0 0.7 2.6 0.9 0.1 0.3 0.2 4.0 9.2 1.9 0.0 2.2 2.3 25.0 4.1 21.6 4.2 1.2 0.4 4.9 5.7 1.0 1.2 4.8 6.3 0.2 9.2 12.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.2 0.5 0.0 18.0 0.1 0.0 0.1 2.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.7 0.1 0.9 2.0 0.7 4.0 1.2 1.0 0.4 1.2 3.2 7.5 2.3 0.5 0.9 0.4 0.0 0.0 1.1 0.2 0.3 4.8 0.0 3.7 0.0 0.0 0.1 0.1 22.9 1.9 0.0 17.0 0.0 0.2 5.0 0.0 0.0 1.3 0.0 0.1 24.8 0.0 0.1 7.6 0.1 0.7 2.3 0.4 1.7 5.8 3.6 2.0 0.8 0.8 10.6 0.0 2.3 1.8 1.0 0.0 0.0 0.0 0.5 0.7 0.1 8.3 0.0 0.1 0.8 34.1 1.2 4.0 0.7 0.0 283.7 4.5 0.9 1.1 0.0 0.6 0.3 1.6 2.9 5.5 4.7 HP ENSG00000257017 Haptoglobin P00738 16 72054505-72061055 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Immunity" "Antibiotic, Antimicrobial, Antioxidant, Serine protease homolog" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 91 "liver: 61113.6" "Cell type enriched" "Detected in many" 43 "Hepatocytes: 59512.7" "Cancer enriched" "Detected in many" 81 "liver cancer: 1297.4" "Region enhanced" "Detected in all" "medulla oblongata: 29.7" "Group enriched" "Detected in many" 5 "classical monocyte: 49.3;eosinophil: 80.2" "Group enriched" "Detected in many" 7 "granulocytes: 80.2;monocytes: 49.3" "Group enriched" "Detected in some" 5 "Hep G2: 232.2;HSkMC: 121.4" "CAB003787, HPA047750, HPA066795" Enhanced Approved Vesicles "Secreted to blood" NA NA 998000000000 100000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB003787: , HPA047750: AB_2680146, HPA066795: " "unprognostic (6.38e-3)" "unprognostic (7.73e-3)" "unprognostic (1.23e-1)" "unprognostic (2.41e-2)" "unprognostic (2.34e-3)" "unprognostic (2.07e-1)" "unprognostic (7.79e-3)" "unprognostic (1.37e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "unprognostic (6.30e-2)" "unprognostic (8.18e-2)" "prognostic unfavorable (6.94e-13)" "unprognostic (4.34e-4)" "unprognostic (1.80e-1)" "unprognostic (6.61e-2)" "unprognostic (2.49e-2)" 673.1 11.4 1.3 26.9 1.7 231.5 34.2 1.4 2.9 71.9 3.6 3.6 1.5 3.5 2.9 5.3 74.6 1.3 146.7 1.4 1.4 19.8 61113.6 91.3 1.7 29.7 2.0 9.9 7.6 0.2 49.9 2.5 3.7 7.3 0.6 0.7 6.1 0.2 5.0 3.4 4.4 4.5 2.3 72.0 6.2 2.1 8.3 2.7 6.3 0.4 3.0 3.8 3.3 5.9 0.0 0.0 0.0 0.0 6.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 8.5 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 11.2 0.2 232.2 0.3 33.3 6.2 121.4 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 2.0 0.4 2.6 0.0 0.0 1.1 23.6 0.0 0.0 0.1 0.0 0.0 16.2 0.0 0.0 0.0 0.0 6.8 5.1 0.0 0.8 0.0 0.0 3.9 0.0 14.1 0.0 12.7 0.0 6.2 49.3 80.2 0.0 2.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 14.2 0.0 2.1 0.0 0.0 15.2 1.3 1.7 1.4 2.9 1.4 1.4 29.7 2.0 3.7 2.3 8.3 5.9 0.4 19.2 228.7 1.6 96.1 0.1 0.7 1.9 0.0 0.4 0.4 0.3 66.6 1085.2 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 56.7 0.0 1128.3 0.0 10.4 0.1 45.5 0.0 1.3 3.8 0.4 1038.7 59512.7 2.3 0.0 0.0 0.2 4.1 1381.4 0.0 0.5 10.2 7.8 1.8 0.0 0.3 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 1.5 7.5 0.2 0.0 2.6 1.8 0.0 0.0 0.1 0.3 0.1 90.3 0.0 0.3 0.1 HPR ENSG00000261701 "Haptoglobin-related protein" P00739 16 72063148-72077246 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 811.9" "Group enriched" "Detected in some" 14 "Hepatocytes: 503.0;Smooth muscle cells: 128.8" "Cancer enriched" "Detected in some" 53 "liver cancer: 185.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 50.6" HPA047750 Supported Approved Vesicles "Secreted to blood" NA NA 49000000000 55000000000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA047750: AB_2680146" "unprognostic (2.43e-1)" "unprognostic (4.69e-2)" "unprognostic (5.97e-3)" "unprognostic (2.42e-1)" "unprognostic (2.32e-3)" "unprognostic (2.36e-1)" "unprognostic (1.66e-1)" "unprognostic (8.21e-2)" "unprognostic (2.30e-1)" "unprognostic (3.44e-6)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" 5.5 0.5 14.1 0.2 15.3 0.1 2.0 13.9 16.7 1.2 11.3 1.2 0.6 0.3 0.4 0.3 1.3 0.7 137.2 13.7 14.3 4.0 811.9 1.5 0.7 14.4 14.3 2.0 0.6 0.0 0.3 0.0 13.6 1.6 0.1 0.8 0.3 0.3 1.7 0.6 1.1 0.1 12.8 0.3 1.7 1.9 15.2 0.2 1.1 0.2 0.1 0.4 1.9 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.6 2.2 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.2 0.0 0.1 0.0 0.6 0.6 0.0 14.1 15.3 13.9 16.7 13.7 14.3 14.4 14.3 13.6 12.8 15.2 13.1 0.0 0.0 7.5 2.3 0.4 0.1 0.0 0.9 0.0 0.1 0.0 0.0 22.4 12.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.8 0.0 5.3 0.2 0.2 0.0 2.6 0.0 0.0 0.0 1.1 10.8 503.0 0.0 0.0 0.2 0.0 2.0 12.8 0.0 2.8 9.9 0.0 0.0 0.0 0.0 4.9 0.0 0.0 1.2 0.0 0.0 5.3 0.0 0.0 0.0 13.0 0.2 0.1 0.0 6.1 128.8 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.2 0.0 HS3ST1 3OST1 ENSG00000002587 "Heparan sulfate-glucosamine 3-sulfotransferase 1" O14792 4 11393150-11429564 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.4;ovary: 31.9" "Cell type enhanced" "Detected in many" "Club cells: 112.0;granulocytes: 96.3;Granulosa cells: 285.0;Peritubular cells: 90.3;Urothelial cells: 92.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 25.4" "Group enriched" "Detected in some" 36 "memory B-cell: 14.9;naive B-cell: 26.6;plasmacytoid DC: 42.3" "Group enriched" "Detected in many" 108 "B-cells: 26.6;dendritic cells: 42.3" "Cell line enhanced" "Detected in some" "A-431: 5.8;CAPAN-2: 20.6;HaCaT: 6.0;RPTEC TERT1: 13.2;RT4: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002237 Approved Approved Vesicles "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA002237: AB_1079085" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (4.01e-2)" "prognostic favorable (7.73e-4)" "unprognostic (3.32e-2)" "unprognostic (8.90e-3)" "unprognostic (4.21e-1)" "unprognostic (2.08e-1)" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "prognostic favorable (5.99e-8)" "unprognostic (9.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.57e-1)" "prognostic favorable (8.67e-4)" 2.6 2.5 2.3 2.7 1.9 2.0 1.9 25.4 6.9 2.4 0.0 2.1 3.7 3.4 1.3 11.6 4.4 12.7 1.9 1.6 4.7 5.9 0.4 1.8 2.3 4.7 3.3 31.9 1.0 0.1 4.7 0.7 3.8 2.0 1.1 1.0 5.6 1.5 0.4 0.5 2.9 0.9 4.4 3.3 6.5 1.3 5.8 1.3 1.6 0.2 1.2 14.5 2.6 6.1 5.8 1.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 20.6 0.0 0.4 0.0 0.0 6.0 0.0 2.8 0.0 0.3 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.1 1.6 2.2 1.2 0.0 0.0 13.2 14.5 4.6 0.0 0.0 0.1 0.4 0.2 0.0 0.0 2.0 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.2 14.9 0.0 0.0 0.7 26.6 0.0 0.0 0.0 0.0 0.0 42.3 0.0 1.1 2.3 1.9 25.4 6.9 1.6 4.7 4.7 3.3 3.8 4.4 5.8 6.1 3.5 3.2 5.8 0.0 13.1 9.1 13.5 70.1 5.2 3.7 2.4 9.3 3.2 32.9 112.0 20.2 4.2 0.5 21.6 5.2 0.0 25.0 1.7 3.6 1.0 28.9 2.4 0.0 13.4 2.1 42.1 13.2 23.9 14.9 96.3 285.0 25.0 0.4 37.6 1.7 35.0 7.2 71.2 3.5 3.7 2.0 8.7 12.5 1.8 6.5 4.9 32.9 8.2 24.1 0.7 51.9 6.5 90.3 0.0 5.6 2.7 19.1 61.2 2.6 0.0 0.5 17.5 5.4 5.6 36.6 8.1 1.4 1.4 68.5 4.3 92.9 HS3ST3B1 "30ST3B1, 3OST3B1" ENSG00000125430 "Heparan sulfate-glucosamine 3-sulfotransferase 3B1" Q9Y662 17 14301081-14349404 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 28.4;retina: 11.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.6;dendritic cells: 32.5;Hepatic stellate cells: 25.7;Hepatocytes: 39.7;Syncytiotrophoblasts: 36.3" "Cancer enhanced" "Detected in many" "liver cancer: 5.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 35.1" "Group enriched" "Detected in many" 5 "dendritic cells: 35.1;T-cells: 26.2" "Cell line enhanced" "Detected in many" "AF22: 20.7;BEWO: 14.9;Hep G2: 18.8;HSkMC: 20.2;U-251 MG: 19.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA064126 Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA064126: AB_2685194" "unprognostic (1.74e-1)" "unprognostic (1.13e-1)" "unprognostic (2.29e-2)" "unprognostic (5.55e-3)" "unprognostic (2.85e-3)" "unprognostic (5.22e-2)" "unprognostic (5.03e-3)" "unprognostic (1.79e-1)" "unprognostic (2.93e-1)" "unprognostic (8.13e-3)" "unprognostic (8.80e-2)" "unprognostic (1.13e-1)" "unprognostic (1.02e-3)" "unprognostic (7.77e-3)" "unprognostic (9.46e-2)" "unprognostic (1.91e-1)" "unprognostic (1.54e-3)" 0.9 0.9 0.2 4.6 1.0 1.4 0.9 0.3 1.3 2.4 1.5 1.2 1.3 0.6 0.2 1.8 0.9 1.4 1.5 0.4 0.4 3.0 28.4 1.6 6.3 5.4 2.5 3.5 0.6 0.3 0.7 3.5 2.0 2.0 1.7 11.5 5.3 2.0 1.0 1.5 1.8 0.5 2.9 3.4 1.2 0.4 1.4 3.2 0.7 0.9 4.8 2.6 1.9 0.9 0.0 0.4 20.7 0.0 6.2 6.9 14.9 6.1 8.7 5.3 5.6 0.0 0.1 0.0 0.0 8.2 0.0 0.1 0.5 3.3 2.7 1.8 4.5 0.5 2.9 18.8 8.1 0.8 3.2 20.2 1.1 1.9 4.8 1.2 0.0 1.1 6.6 0.1 4.3 1.1 1.0 0.8 0.7 0.1 0.6 3.9 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.8 0.4 0.6 0.0 5.2 0.0 0.1 19.9 0.0 0.0 0.0 4.0 0.0 1.2 0.2 0.4 0.0 10.2 0.7 8.1 0.9 12.0 8.0 0.8 0.7 12.1 11.8 0.9 6.6 0.8 35.1 26.2 5.1 0.2 1.0 0.3 1.3 0.4 0.4 5.4 2.5 2.0 2.9 1.4 0.9 2.9 0.0 1.1 6.2 3.5 11.5 0.3 4.9 21.1 3.2 1.2 2.2 3.0 10.0 3.9 7.3 39.6 7.2 32.5 0.0 0.0 0.7 14.3 0.3 1.5 2.9 0.0 0.4 3.3 0.2 11.9 6.6 0.0 0.8 0.0 2.4 25.7 39.7 1.6 8.4 2.2 0.1 2.0 3.8 12.9 3.3 2.8 6.7 1.8 1.9 1.3 7.3 14.4 3.5 0.1 0.2 0.0 1.2 2.2 1.1 0.4 0.1 3.9 17.9 13.1 15.0 2.6 4.0 0.3 10.0 14.8 36.3 12.4 0.1 0.2 0.3 HSD11B1L "HSD1L, SCDR10, SDR26C2" ENSG00000167733 "Hydroxysteroid 11-beta dehydrogenase 1 like" Q7Z5J1 19 5680604-5688523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 58.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 19.0" "Low region specificity" "Detected in all" HPA049078 Supported Vesicles "Secreted in brain" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA049078: AB_2680622" "unprognostic (2.34e-2)" "unprognostic (1.10e-1)" "unprognostic (4.73e-3)" "unprognostic (5.26e-2)" "unprognostic (9.37e-2)" "prognostic favorable (4.38e-4)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (1.18e-3)" "unprognostic (1.43e-1)" "unprognostic (3.33e-2)" "unprognostic (1.75e-1)" "unprognostic (5.77e-2)" "unprognostic (4.52e-1)" "unprognostic (1.73e-2)" 3.9 9.8 46.6 1.3 46.7 2.6 5.1 32.0 58.2 5.5 34.0 8.4 1.6 5.4 5.1 3.7 6.7 3.0 5.9 46.1 41.8 12.4 5.4 4.4 1.4 38.4 36.5 6.7 7.0 7.3 21.2 1.5 37.2 6.1 1.0 6.3 5.8 4.1 10.9 9.3 3.4 1.6 32.9 3.2 6.3 8.1 42.4 1.6 8.6 3.3 1.0 6.0 4.3 39.1 3.6 3.0 11.3 2.1 5.0 5.7 2.2 2.7 4.4 1.1 4.8 1.3 3.3 0.8 5.9 2.2 0.9 1.7 1.4 1.8 1.0 3.2 3.6 2.3 3.0 2.2 3.6 0.9 7.9 5.5 3.9 1.6 1.6 10.4 1.8 5.1 2.4 2.9 4.6 0.3 2.1 2.1 3.0 14.2 4.1 3.6 0.5 3.1 9.5 0.8 3.2 19.0 0.5 1.6 12.8 3.8 2.6 0.7 3.2 2.7 5.0 4.9 2.2 7.6 2.8 0.9 7.7 1.2 2.4 1.5 1.0 0.5 0.6 2.7 0.6 0.5 1.4 1.6 1.0 1.1 1.8 1.7 1.9 0.7 1.8 2.2 0.4 0.9 46.6 46.7 32.0 58.2 46.1 41.8 38.4 36.5 37.2 32.9 42.4 39.1 8.2 0.0 2.6 13.7 2.6 8.2 8.6 12.9 9.6 11.3 23.7 23.1 2.3 10.0 8.6 23.9 14.6 4.7 3.0 4.5 15.6 12.4 9.5 21.8 6.0 6.1 25.7 1.3 24.7 4.7 6.5 8.1 4.6 5.4 10.2 12.4 8.9 4.1 5.1 8.4 20.4 4.6 12.2 2.8 6.0 13.9 7.2 2.4 5.4 1.9 3.1 30.5 1.0 14.1 4.6 4.8 4.3 12.8 0.9 8.4 4.1 33.3 31.2 12.9 0.0 8.1 9.5 10.8 12.7 4.8 10.2 2.9 3.1 16.6 3.7 9.7 HSD17B3 SDR12C2 ENSG00000130948 "Hydroxysteroid 17-beta dehydrogenase 3" P37058 9 96235306-96302176 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.1;testis: 36.7" "Group enriched" "Detected in some" 6 "Leydig cells: 108.1;Oligodendrocytes: 93.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 2.3;HEL: 1.0;U-2 OS: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA056833 Enhanced Approved Vesicles NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA056833: AB_2683252" "unprognostic (2.78e-1)" "unprognostic (6.61e-3)" "unprognostic (1.03e-1)" "unprognostic (5.76e-2)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (3.08e-2)" "unprognostic (6.15e-2)" "unprognostic (1.74e-1)" "unprognostic (5.13e-2)" "unprognostic (3.26e-4)" "unprognostic (3.45e-1)" "unprognostic (5.48e-8)" "unprognostic (8.47e-3)" "unprognostic (1.15e-1)" "unprognostic (7.24e-2)" "unprognostic (3.11e-2)" 1.6 0.8 3.1 0.2 4.3 0.0 1.7 3.4 5.9 3.1 2.4 2.7 0.5 1.5 0.9 0.7 3.5 0.2 2.1 3.1 3.6 4.7 15.1 1.8 0.0 4.3 3.9 1.4 4.2 0.0 1.7 0.1 4.2 3.2 0.1 0.7 1.0 0.1 0.5 0.9 3.7 0.0 3.3 0.9 1.4 36.7 4.2 0.1 10.0 0.1 0.0 1.6 1.8 5.4 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.0 0.0 0.0 1.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.1 4.3 3.4 5.9 3.1 3.6 4.3 3.9 4.2 3.3 4.2 5.4 0.0 0.0 0.0 15.3 0.2 0.0 0.1 0.8 0.0 0.2 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.2 4.0 0.2 0.0 0.4 1.8 0.0 0.5 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 2.5 0.0 0.0 0.5 0.5 0.0 0.0 0.4 14.4 108.1 1.1 0.0 4.7 0.1 0.6 0.0 1.0 93.2 0.2 0.1 12.8 0.0 0.1 0.6 0.0 0.5 0.2 0.0 0.1 0.5 1.9 1.8 0.0 0.3 0.1 0.0 0.0 0.3 0.0 HTRA3 "Prsp, Tasp" ENSG00000170801 "HtrA serine peptidase 3" P83110 4 8269754-8307098 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 194.9" "Cell type enhanced" "Detected in some" "Fibroblasts: 158.8;Leydig cells: 43.5;Peritubular cells: 42.9;Skeletal myocytes: 99.0;Theca cells: 25.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 67.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "U-2197: 182.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA021187, HPA063810" Approved Approved Vesicles "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA021187: AB_1851311, HPA063810: AB_2685129" "unprognostic (5.87e-2)" "unprognostic (1.40e-2)" "unprognostic (2.89e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-1)" "unprognostic (3.09e-2)" "unprognostic (1.12e-3)" "unprognostic (5.29e-2)" "unprognostic (3.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.95e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (1.61e-9)" "unprognostic (1.65e-3)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.34e-2)" 68.0 6.0 0.9 8.7 1.3 13.4 50.4 0.9 1.3 35.4 5.0 33.9 8.7 42.4 10.6 15.1 26.2 35.5 194.9 0.9 1.0 6.2 3.2 38.0 1.2 1.0 1.0 93.0 6.8 0.4 15.7 20.4 1.0 26.3 4.8 0.1 22.8 6.7 32.1 28.1 16.9 11.8 1.0 2.9 21.9 4.3 1.7 2.2 26.0 12.9 0.7 62.4 32.6 0.7 0.0 1.0 1.4 0.0 5.8 10.8 0.3 2.4 0.2 2.8 0.6 0.1 0.1 0.0 13.6 6.4 1.4 0.1 1.2 0.0 0.9 0.0 2.3 1.3 13.9 0.0 6.1 0.0 0.6 1.2 0.0 4.2 0.0 1.7 9.8 0.0 0.3 0.0 10.2 0.0 0.2 36.5 6.1 0.0 0.3 0.3 0.0 0.1 0.0 0.0 15.8 0.3 26.4 0.5 0.2 28.8 0.1 1.1 8.1 1.4 4.7 182.1 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 1.3 0.9 1.3 0.9 1.0 1.0 1.0 1.0 1.0 1.7 0.7 12.6 0.0 0.0 0.0 0.0 5.2 0.5 0.0 0.6 0.0 0.5 0.9 16.5 0.0 0.6 0.0 0.0 0.8 0.1 0.0 0.0 0.1 1.2 0.3 8.1 5.3 0.0 0.0 0.0 0.0 4.2 158.8 0.5 0.3 0.0 6.0 3.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 8.6 1.4 43.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.9 0.4 0.4 0.0 0.1 0.0 0.0 0.0 99.0 10.6 0.4 0.7 0.6 5.3 1.4 0.9 25.2 0.0 0.2 IAPP "AMYLIN, DAP, IAP" ENSG00000121351 "Islet amyloid polypeptide" P10997 12 21354959-21379980 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "pancreas: 166.7" "Group enriched" "Detected in some" 5 "Early spermatids: 44.5;Pancreatic endocrine cells: 15.2" "Cancer enriched" "Detected in single" 76 "pancreatic cancer: 21.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2 OS: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000352, HPA053194" Enhanced Approved Vesicles "Secreted to blood" NA NA 11900 "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "CAB000352: AB_2121635, HPA053194: AB_2682076" "unprognostic (5.52e-3)" "unprognostic (1.00e-1)" "unprognostic (4.16e-1)" "unprognostic (1.74e-1)" "unprognostic (1.91e-1)" 0.5 0.0 0.1 0.0 0.2 1.0 0.0 0.5 0.3 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 2.3 0.0 0.2 0.1 0.5 0.0 166.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 3.1 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.1 0.3 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.5 0.3 0.1 0.2 0.1 0.5 0.2 0.0 0.8 0.5 0.0 0.0 1.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 44.5 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 5.9 0.3 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 1.5 0.3 0.3 0.2 0.0 0.4 0.3 0.3 0.1 0.0 0.8 IDI2 IPPI2 ENSG00000148377 "Isopentenyl-diphosphate delta isomerase 2" Q9BXS1 10 1018910-1025859 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "skeletal muscle: 273.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Glandular and luminal cells: 1.1;Horizontal cells: 1.7;Skeletal myocytes: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041254 Uncertain Vesicles NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Vesicles "HPA041254: AB_10794270" "unprognostic (6.69e-3)" "unprognostic (4.05e-2)" "unprognostic (1.64e-1)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.0 1.2 0.0 0.0 273.8 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.1 0.0 11.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.7 0.4 0.3 0.0 0.1 0.2 0.2 0.0 0.6 0.3 0.5 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.4 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.9 0.5 0.4 0.2 0.0 0.0 0.3 0.0 0.1 0.1 0.0 1.1 0.0 0.1 0.0 0.0 0.2 1.7 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.2 0.3 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.2 IDUA "MPS1, MPSI" ENSG00000127415 Alpha-L-iduronidase P35475 4 986997-1004564 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 29.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025901, HPA046979, HPA054254" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 170000 "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB025901: , HPA046979: AB_2679888, HPA054254: AB_2682429" "unprognostic (3.62e-2)" "unprognostic (9.08e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (7.23e-2)" "unprognostic (1.45e-1)" "unprognostic (2.31e-2)" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.43e-2)" "unprognostic (1.89e-3)" "unprognostic (2.64e-2)" "unprognostic (4.61e-3)" "prognostic unfavorable (7.87e-5)" "unprognostic (2.24e-1)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "prognostic favorable (8.04e-5)" 13.5 17.6 3.4 2.2 3.4 2.9 16.1 9.2 7.5 17.5 2.9 10.3 3.6 15.4 2.4 9.9 16.3 3.7 11.6 3.8 1.5 15.9 13.6 13.9 3.5 3.2 2.1 17.0 21.0 2.8 17.2 1.7 2.4 18.5 1.8 1.8 16.6 4.5 3.7 8.9 14.3 2.0 1.0 18.9 17.1 5.6 2.9 3.4 17.0 0.7 1.3 12.0 13.9 2.6 1.8 0.4 0.0 1.1 12.7 3.6 5.3 10.7 8.5 1.2 1.7 0.6 6.4 0.8 10.7 5.0 1.0 0.5 0.1 0.3 0.4 6.1 0.6 1.0 0.8 0.1 5.8 0.8 4.6 9.3 3.1 0.6 0.0 3.4 1.0 0.7 0.6 0.0 1.6 0.0 2.2 2.5 0.8 11.9 5.5 2.7 0.0 1.1 3.5 0.9 0.1 3.3 0.3 0.0 5.7 1.3 1.2 2.3 9.3 9.0 1.6 2.6 1.2 29.0 1.4 0.4 7.8 3.3 1.8 0.0 1.5 0.0 1.4 1.2 1.8 0.1 1.1 0.9 1.8 0.2 1.3 0.7 0.0 1.5 1.7 1.1 0.6 0.5 3.4 3.4 9.2 7.5 3.8 1.5 3.2 2.1 2.4 1.0 2.9 2.6 8.7 6.4 5.0 4.9 5.2 3.6 11.5 1.1 8.6 2.0 8.5 9.1 2.6 1.5 1.5 7.3 4.2 0.4 4.3 5.0 0.0 1.6 0.9 4.1 9.0 4.9 10.7 1.3 4.4 2.4 1.7 13.4 16.8 6.0 2.5 8.2 6.1 2.6 6.5 0.0 2.9 4.2 0.0 5.0 3.6 0.9 19.6 7.3 5.4 1.0 1.6 1.1 4.1 5.5 3.3 1.4 6.9 10.5 15.7 7.7 6.9 1.4 1.4 2.1 0.0 5.5 4.4 3.7 1.6 4.7 1.8 0.4 5.6 4.7 4.3 7.9 IFIT2 "cig42, G10P2, GARG-39, IFI-54, IFI54, ISG-54K" ENSG00000119922 "Interferon induced protein with tetratricopeptide repeats 2" P09913 10 89283694-89309271 "Predicted intracellular proteins" "Antiviral defense, Apoptosis, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 48.4" "Cell type enhanced" "Detected in many" "Adipocytes: 53.5;Glandular and luminal cells: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 420.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 420.2" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 141.0;BJ hTERT+ SV40 Large T+ RasG12V: 113.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003408 Approved Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA003408: AB_1079100" "unprognostic (1.77e-1)" "unprognostic (2.10e-1)" "unprognostic (2.42e-2)" "unprognostic (2.25e-3)" "unprognostic (1.75e-2)" "unprognostic (9.28e-2)" "unprognostic (6.71e-3)" "unprognostic (2.22e-1)" "unprognostic (5.40e-1)" "unprognostic (1.36e-1)" "unprognostic (7.03e-3)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.99e-4)" "unprognostic (2.92e-2)" "unprognostic (1.03e-2)" "unprognostic (5.33e-3)" "unprognostic (6.46e-2)" 7.7 6.7 12.6 13.1 17.3 48.4 5.4 14.7 16.2 6.1 8.2 5.4 6.7 5.0 6.2 2.8 9.3 13.6 7.5 11.7 14.1 10.2 21.8 21.0 7.9 19.5 16.6 9.2 3.1 10.0 2.5 16.4 18.9 4.1 4.5 1.7 8.8 6.5 2.3 3.7 5.7 6.5 30.1 27.5 3.6 2.2 15.9 12.6 3.4 6.8 5.7 6.3 2.9 20.8 29.3 1.1 0.3 14.5 13.0 14.4 5.2 10.7 32.4 141.0 113.0 0.1 20.0 3.2 5.9 7.8 20.6 28.9 0.6 1.5 15.4 11.6 0.1 5.3 14.3 0.0 22.2 0.7 2.3 8.2 0.7 10.7 1.6 8.6 0.7 2.8 0.1 0.5 2.2 0.1 3.4 6.6 3.5 0.0 6.1 2.1 3.7 0.8 4.8 5.6 0.1 0.2 3.8 0.6 24.7 1.8 0.7 1.6 0.9 1.5 0.3 3.9 1.1 1.4 5.1 0.5 2.3 2.4 2.9 97.6 32.6 107.8 9.5 75.9 5.1 19.2 8.0 6.5 10.6 17.7 7.6 6.8 420.2 8.9 92.3 12.7 3.9 17.6 12.6 17.3 14.7 16.2 11.7 14.1 19.5 16.6 18.9 30.1 15.9 20.8 53.5 41.7 6.7 1.6 12.3 1.5 5.3 6.6 1.2 1.3 5.6 9.5 7.4 11.5 9.4 12.9 0.0 2.9 27.6 23.5 9.8 35.0 0.2 34.9 9.1 34.9 3.5 0.8 1.0 4.2 1.6 10.9 2.0 67.0 5.1 3.8 16.4 6.1 26.0 25.2 2.1 5.9 4.1 25.5 3.3 0.2 8.1 29.5 7.2 4.7 20.9 13.3 12.3 2.0 20.3 6.3 11.5 11.7 2.4 19.1 18.9 30.8 4.7 0.9 0.0 8.3 14.3 0.2 0.2 3.2 0.6 1.4 13.1 6.2 2.1 5.8 IGIP "C5orf53, LOC492311" ENSG00000182700 "IgA inducing protein" A6NJ69 5 140125937-140129392 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 55.4" "Cell type enhanced" "Detected in many" "Horizontal cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.7;ASC TERT1: 13.1" "Low region specificity" "Detected in all" "HPA041877, HPA048615" Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA041877: AB_2677721, HPA048615: AB_2680462" "unprognostic (1.15e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" "unprognostic (2.00e-2)" "unprognostic (2.46e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (1.10e-1)" "unprognostic (2.38e-1)" "unprognostic (5.05e-2)" "prognostic favorable (3.94e-4)" "unprognostic (1.94e-1)" "prognostic favorable (6.25e-6)" "unprognostic (2.93e-3)" "unprognostic (1.70e-1)" "unprognostic (5.98e-2)" "unprognostic (7.77e-2)" 8.3 8.9 43.6 2.9 41.0 0.1 7.7 38.9 55.4 12.7 29.7 14.1 3.7 9.2 9.0 6.3 8.9 3.7 11.8 38.3 40.9 9.3 10.0 9.4 4.5 41.5 43.8 9.9 8.4 13.7 18.6 4.2 43.9 12.0 3.8 19.5 8.0 8.1 10.4 9.0 8.3 4.6 45.7 7.8 9.2 4.0 45.1 4.2 11.9 9.2 3.9 10.7 11.6 40.8 2.0 0.6 0.9 2.8 13.7 13.1 1.3 5.1 5.0 1.1 1.5 2.0 1.6 3.8 5.3 6.9 0.6 2.1 1.1 3.1 2.3 3.4 1.9 0.8 3.0 1.5 3.2 1.0 1.3 4.5 7.7 2.2 4.2 8.6 1.4 2.8 0.6 1.5 4.4 1.8 1.2 2.6 0.2 1.6 1.5 1.2 2.4 1.7 6.6 1.8 1.0 1.5 2.8 1.8 3.1 1.0 1.4 3.0 8.8 3.5 0.3 1.2 2.8 3.6 2.5 1.3 3.7 2.6 2.6 0.0 0.0 0.2 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.2 0.0 43.6 41.0 38.9 55.4 38.3 40.9 41.5 43.8 43.9 45.7 45.1 40.8 6.5 12.8 5.1 14.0 2.3 2.0 2.1 3.2 0.0 21.3 4.5 3.7 14.4 8.6 5.4 3.7 14.6 2.5 1.4 5.5 0.0 3.3 1.9 2.4 3.5 5.4 9.0 0.0 22.2 1.8 1.5 4.4 3.6 2.2 8.2 3.0 7.9 5.9 1.0 28.6 19.8 4.2 0.0 2.2 1.3 1.3 6.5 2.2 7.2 14.0 3.9 5.9 3.1 9.5 17.6 2.8 4.4 17.0 1.3 3.7 7.8 4.2 6.1 8.8 0.0 11.2 5.5 2.4 1.3 1.7 4.0 1.8 1.9 2.8 4.0 2.2 IGSF10 "CMF608, FLJ25972" ENSG00000152580 "Immunoglobulin superfamily member 10" Q6WRI0 3 151425384-151458709 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 17.7" "Cell type enhanced" "Detected in many" "Early spermatids: 170.5;Horizontal cells: 60.6;Late spermatids: 34.1;Microglial cells: 61.8;Syncytiotrophoblasts: 30.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HeLa: 44.1;HL-60: 23.3;REH: 17.2;RPMI-8226: 55.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA012655, HPA012921" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 540000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA012655: , HPA012921: AB_1851526" "unprognostic (1.78e-3)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.47e-7)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (9.82e-2)" "unprognostic (8.84e-4)" "unprognostic (9.38e-3)" "unprognostic (1.96e-1)" "unprognostic (5.70e-2)" "unprognostic (2.04e-1)" "unprognostic (7.52e-4)" "unprognostic (6.01e-2)" "unprognostic (8.93e-2)" "unprognostic (4.59e-3)" "unprognostic (7.57e-4)" 3.9 4.0 1.4 0.9 0.7 0.6 6.1 0.3 1.0 0.5 3.2 1.3 0.5 1.4 1.6 2.9 4.3 9.7 4.3 2.8 1.1 0.2 0.3 8.6 1.4 0.1 1.0 17.7 0.7 1.3 1.7 0.7 0.3 0.1 1.3 0.2 5.2 0.2 0.1 1.9 1.2 1.5 0.0 0.9 0.7 0.9 3.6 1.3 1.5 0.5 2.5 2.2 0.3 0.3 0.0 0.1 0.3 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.1 0.0 0.4 0.0 0.0 0.3 0.3 7.5 44.1 0.0 1.6 23.3 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.2 0.1 55.1 0.1 0.1 1.0 0.0 5.9 0.0 0.0 0.2 0.0 0.2 0.0 0.1 1.1 0.0 0.0 2.4 0.0 0.0 0.2 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.7 0.3 1.0 2.8 1.1 0.1 1.0 0.3 0.0 3.6 0.3 2.0 0.0 0.5 1.0 0.6 2.4 1.2 0.5 2.8 15.8 0.6 0.9 1.6 2.8 6.3 1.8 4.2 21.7 2.7 0.2 0.0 0.1 170.5 11.4 4.0 0.9 6.0 3.4 2.4 1.3 2.9 20.4 0.5 0.5 0.0 0.0 0.0 0.1 1.3 60.6 2.8 0.7 4.1 0.8 3.2 34.1 6.8 2.9 3.6 61.8 1.1 25.6 0.0 0.5 0.7 0.4 0.1 1.2 0.3 0.7 0.0 0.3 12.5 2.4 0.0 0.5 2.2 10.7 7.9 0.8 2.4 30.9 0.6 2.5 0.1 0.2 IGSF8 "CD316, CD81P3, EWI2, PGRL" ENSG00000162729 "Immunoglobulin superfamily member 8" Q969P0 1 160091340-160098943 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 155.3" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 177.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011917, HPA075970" Approved Supported Vesicles NA NA 280000 "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA011917: AB_1851536, HPA075970: " "unprognostic (4.08e-1)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.30e-2)" "unprognostic (9.31e-2)" "unprognostic (1.46e-1)" "unprognostic (1.20e-1)" "unprognostic (1.71e-1)" "unprognostic (1.01e-3)" "unprognostic (1.63e-2)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (2.31e-1)" "unprognostic (2.60e-2)" "unprognostic (2.35e-1)" "unprognostic (3.74e-3)" "unprognostic (1.75e-3)" 21.9 19.1 97.9 14.0 119.0 3.7 26.7 91.7 130.7 25.7 39.9 31.7 26.5 19.8 22.7 22.3 28.2 12.3 29.0 106.0 82.4 35.5 53.9 23.6 16.8 109.3 97.8 37.5 31.8 15.8 30.7 11.2 99.9 26.4 10.4 14.3 30.1 18.2 12.4 50.3 28.5 7.0 98.6 24.2 27.5 33.4 94.7 13.6 28.6 7.1 8.9 20.3 25.0 155.3 26.8 15.7 20.1 51.3 11.6 7.3 42.9 12.9 16.8 26.9 25.0 17.9 17.9 39.0 47.1 18.8 23.4 50.3 8.2 18.9 3.8 47.3 15.0 5.1 17.3 31.2 19.2 13.5 41.7 9.0 37.7 17.5 5.6 19.0 5.6 42.0 7.0 21.8 6.3 25.4 33.8 31.3 42.4 55.6 24.8 19.1 10.3 28.7 24.7 27.4 8.5 36.6 14.8 47.4 177.6 17.5 33.7 17.3 5.8 11.8 25.4 21.5 10.6 59.6 71.2 17.7 41.6 5.3 31.6 0.1 5.2 2.4 22.0 7.2 19.5 19.6 18.0 25.6 5.8 22.7 23.4 25.7 1.4 9.2 4.7 9.9 26.9 11.3 97.9 119.0 91.7 130.7 106.0 82.4 109.3 97.8 99.9 98.6 94.7 155.3 12.2 9.6 3.3 18.3 21.1 43.7 30.2 43.1 26.2 55.6 28.0 29.2 3.3 17.2 16.7 38.6 10.4 32.8 15.1 36.1 5.9 34.2 3.8 12.0 7.2 7.8 19.9 7.4 65.3 12.4 219.7 22.4 6.6 26.4 10.2 12.2 13.2 28.8 14.9 65.6 43.8 24.7 44.7 4.3 16.2 1.1 16.8 8.5 42.7 9.4 51.5 75.7 10.3 9.0 107.2 20.6 39.5 15.8 20.0 22.0 47.6 15.8 6.0 11.8 6.6 39.8 15.3 4.0 6.6 21.0 62.4 69.4 19.5 13.6 32.6 26.0 IL27RA "CRL1, IL-27R, TCCR, WSX-1, WSX1, zcytor1" ENSG00000104998 "Interleukin 27 receptor subunit alpha" Q6UWB1 19 14031762-14053218 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.5" "Cell type enhanced" "Detected in many" "B-cells: 49.1;dendritic cells: 56.6;Kupffer cells: 41.1;Langerhans cells: 44.2;NK-cells: 69.0;T-cells: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073441 Approved Vesicles NA NA 4900000 "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA073441: " "prognostic favorable (1.74e-6)" "unprognostic (1.99e-1)" "unprognostic (1.55e-1)" "unprognostic (6.09e-2)" "unprognostic (2.03e-3)" "unprognostic (2.28e-1)" "unprognostic (2.05e-2)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (1.40e-3)" "unprognostic (9.92e-2)" "unprognostic (3.35e-2)" "prognostic unfavorable (2.58e-10)" "unprognostic (5.45e-3)" "unprognostic (3.91e-2)" "unprognostic (1.76e-1)" "unprognostic (1.87e-3)" 7.8 1.7 2.4 8.7 2.3 2.7 6.5 2.2 2.7 2.7 2.2 3.1 2.3 2.4 0.7 2.6 3.3 2.3 7.7 2.8 2.9 6.1 1.5 8.0 12.6 2.5 2.5 1.0 2.8 5.6 0.8 1.3 2.7 3.6 2.1 0.2 3.0 1.2 2.0 2.2 8.1 1.9 2.5 14.7 2.8 2.0 3.1 11.1 4.0 2.4 16.5 3.9 2.8 2.4 7.7 3.3 3.2 4.4 0.2 1.6 1.3 3.5 7.3 6.3 9.0 1.6 6.1 0.1 3.6 3.1 2.9 1.4 5.1 2.1 4.8 14.8 3.5 18.6 0.7 2.7 0.5 9.0 0.2 1.6 0.8 3.0 0.6 5.1 2.5 4.6 13.1 13.5 0.3 10.7 6.8 19.5 4.2 4.5 2.2 5.8 1.9 7.1 3.9 1.8 2.8 1.5 4.5 0.3 5.2 1.7 5.6 5.4 4.0 0.6 7.7 6.4 3.8 13.9 7.2 6.7 0.6 18.2 4.2 7.9 22.5 0.6 24.3 18.4 21.4 15.6 24.0 20.2 20.7 12.8 26.1 20.6 1.6 22.9 9.5 7.6 23.1 21.4 2.4 2.3 2.2 2.7 2.8 2.9 2.5 2.5 2.7 2.5 3.1 2.4 30.4 0.0 10.0 0.0 49.1 1.9 13.3 8.5 3.4 0.3 14.0 11.9 5.4 5.7 5.7 3.7 0.0 0.6 56.6 0.7 0.0 10.7 0.4 1.9 1.2 22.8 2.4 7.2 2.4 2.7 1.4 4.0 3.6 1.5 17.7 1.4 22.9 0.7 21.4 1.7 2.1 0.9 4.1 41.1 44.2 0.5 3.4 32.8 5.4 1.0 22.8 0.3 69.0 1.0 0.6 3.8 0.8 3.4 26.0 12.4 0.0 0.9 2.0 0.0 0.0 1.9 2.2 0.1 11.5 2.6 1.3 0.1 63.5 0.4 2.4 3.5 IL2RG "CD132, CIDX, IMD4, SCIDX1" ENSG00000147168 "Interleukin 2 receptor subunit gamma" P31785 X 71107404-71112108 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 118.0;lymphoid tissue: 346.4" "Cell type enhanced" "Detected in many" "B-cells: 186.1;dendritic cells: 199.0;Distal enterocytes: 202.0;NK-cells: 310.0;Paneth cells: 133.2;Plasma cells: 221.2;T-cells: 289.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "Karpas-707: 2316.2" "HPA046641, HPA049691" Enhanced Approved Vesicles NA NA 13000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" Vesicles "HPA046641: AB_2679733, HPA049691: AB_2680851" "unprognostic (2.97e-3)" "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.73e-4)" "unprognostic (8.25e-2)" "unprognostic (1.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.91e-3)" "unprognostic (1.23e-2)" "unprognostic (4.36e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.28e-7)" "unprognostic (1.73e-1)" "unprognostic (4.69e-2)" "unprognostic (4.89e-2)" "unprognostic (9.54e-2)" 12.8 6.2 2.7 132.2 2.4 87.3 14.1 2.5 6.3 10.2 4.0 98.9 50.4 7.5 7.5 15.1 6.8 28.2 4.6 2.3 2.8 7.1 20.6 51.7 235.6 3.6 2.7 4.9 4.1 1.9 1.5 16.9 4.2 7.8 118.0 0.5 19.0 5.9 2.6 15.4 82.8 12.3 3.1 119.4 41.4 2.2 3.0 346.4 5.8 6.3 306.9 46.4 5.5 3.8 1.2 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.2 0.0 4.7 9.1 187.3 13.5 0.0 0.7 1.7 0.4 0.0 0.0 160.3 0.2 23.6 0.3 0.3 0.2 99.3 4.0 0.0 0.0 0.0 0.1 0.1 0.0 220.5 43.3 2316.2 0.0 0.0 356.4 193.7 0.4 0.9 0.1 79.5 0.8 20.0 0.0 0.7 0.2 0.3 2.3 0.1 0.5 0.0 0.0 3.5 0.4 0.0 1.0 0.0 0.5 132.1 242.2 119.6 2.1 397.4 0.9 540.5 102.2 169.7 1204.7 239.5 1179.9 604.7 1086.3 1250.7 243.5 603.0 742.0 943.1 773.0 1190.3 177.0 368.9 1422.2 1494.0 2.7 2.4 2.5 6.3 2.3 2.8 3.6 2.7 4.2 3.1 3.0 3.8 3.3 3.2 11.2 0.0 186.1 8.2 8.1 13.1 1.2 0.0 1.5 1.7 0.9 4.3 4.2 0.0 0.0 0.5 199.0 202.0 0.0 1.2 0.1 0.8 0.7 5.8 77.7 27.1 0.0 2.3 0.3 4.2 13.7 0.7 39.3 0.4 6.1 2.1 31.1 0.0 0.0 24.5 4.1 25.2 116.7 0.0 0.0 45.4 42.7 1.0 91.1 0.1 310.0 0.0 0.1 28.0 133.2 0.4 221.2 4.3 88.8 1.1 2.3 0.4 0.0 1.3 2.6 0.0 0.1 1.8 6.8 0.3 289.5 0.0 18.6 8.9 IL6 "BSF2, HGF, HSF, IFNB2, IL-6" ENSG00000136244 "Interleukin 6" P05231 7 22725884-22732002 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 217.6;urinary bladder: 281.3" "Group enriched" "Detected in many" 4 "Adipocytes: 188.5;Endometrial ciliated cells: 163.9;Endothelial cells: 287.4;Fibroblasts: 593.3;Glandular and luminal cells: 322.2;Smooth muscle cells: 449.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 44 "memory B-cell: 3.9;naive B-cell: 4.8" "Lineage enriched" "Detected in single" 48 "B-cells: 4.8" "Group enriched" "Detected in many" 4 "BJ hTERT+: 2214.7;GAMG: 1447.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB023406, CAB072821" Supported Approved Vesicles "Secreted to blood" NA NA 5700 "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB023406: AB_617317, CAB072821: " "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (3.59e-2)" "unprognostic (9.88e-3)" "unprognostic (1.35e-1)" "unprognostic (3.07e-3)" "unprognostic (3.25e-1)" "unprognostic (2.17e-1)" "unprognostic (2.48e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (1.10e-11)" "unprognostic (2.45e-3)" "unprognostic (2.10e-1)" "unprognostic (4.31e-2)" "unprognostic (7.80e-2)" 217.6 13.9 3.6 30.8 3.8 46.8 31.3 3.7 6.0 4.7 9.2 22.1 1.9 5.7 0.0 34.9 18.9 41.6 55.1 3.8 3.8 17.7 13.0 114.9 9.1 4.0 4.3 6.2 19.5 10.0 38.3 11.3 4.9 16.5 17.3 1.4 12.0 2.0 7.8 7.6 8.3 19.5 3.9 7.0 18.0 1.2 4.7 6.3 14.2 4.1 3.7 281.3 5.7 4.1 0.1 0.0 0.0 0.0 0.7 2.2 7.5 8.9 2214.7 43.2 151.0 0.0 0.6 0.2 71.6 15.2 1447.6 1.7 0.0 0.3 59.9 94.2 0.2 0.0 3.7 0.0 47.3 0.0 0.6 5.6 0.0 413.8 63.1 44.2 18.2 0.0 10.6 0.5 1.9 0.1 0.0 0.3 1.6 0.7 0.5 0.0 0.0 0.0 124.2 0.0 0.0 0.0 144.5 0.1 0.6 7.9 0.1 0.1 14.5 15.2 1.4 28.2 4.7 0.0 27.8 0.4 98.5 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.6 3.8 3.7 6.0 3.8 3.8 4.0 4.3 4.9 3.9 4.7 4.1 188.5 6.4 22.7 0.0 27.0 44.6 3.4 28.5 1.8 0.1 1.4 1.1 1.4 0.0 17.7 3.7 0.0 1.1 0.4 0.1 0.0 9.8 0.4 163.9 44.6 287.4 0.0 0.0 0.0 2.8 4.0 593.3 0.0 322.2 6.3 0.0 3.6 0.1 4.1 0.0 0.0 0.0 0.0 9.3 76.5 0.2 0.0 27.4 40.9 2.8 4.2 0.0 0.0 0.0 0.1 4.3 0.1 0.0 0.9 16.4 0.0 0.0 8.1 0.0 0.0 28.9 449.0 0.0 0.1 0.4 33.4 1.4 8.6 0.2 0.0 20.6 INHBE "activin, MGC4638" ENSG00000139269 "Inhibin subunit beta E" P58166 12 57452323-57459280 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "liver: 148.4" "Cell type enriched" "Detected in single" 43 "Hepatocytes: 35.0" "Cancer enriched" "Detected in some" 27 "liver cancer: 34.4" "Region enhanced" "Detected in some" "cerebellum: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 50.8;Karpas-707: 79.1;RH-30: 36.9;U-266/70: 263.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016843, CAB034017" Enhanced Supported Vesicles "Secreted to blood" NA NA 3500000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" Vesicles "CAB034017: AB_2233745, HPA016843: AB_1851796" "unprognostic (7.34e-2)" "unprognostic (6.73e-2)" "unprognostic (3.45e-1)" "unprognostic (4.69e-5)" "unprognostic (2.61e-1)" "unprognostic (2.50e-1)" "unprognostic (3.13e-1)" "unprognostic (1.24e-1)" "unprognostic (8.79e-3)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.66e-8)" "unprognostic (4.09e-3)" "unprognostic (1.56e-1)" "unprognostic (3.57e-2)" "unprognostic (7.52e-3)" 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.6 0.3 0.2 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.3 148.4 0.1 0.1 0.9 0.0 0.0 0.9 0.1 1.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 1.5 0.1 0.2 0.0 0.0 0.3 0.0 0.2 0.1 0.0 1.4 0.5 0.0 0.2 0.1 0.2 0.2 0.4 0.3 0.5 0.0 0.5 0.3 2.9 7.8 0.2 9.2 0.4 0.1 4.0 1.9 0.7 0.2 0.4 1.8 0.0 1.2 18.3 0.2 0.1 0.3 11.9 50.8 2.3 2.4 4.9 5.3 1.2 11.4 0.4 0.0 1.8 5.0 79.1 0.0 0.0 0.2 0.2 0.5 0.1 0.3 0.2 36.9 8.8 0.0 0.1 19.5 0.9 0.0 0.0 7.6 0.3 0.6 8.7 0.3 0.2 4.0 0.1 0.6 263.5 9.2 3.8 1.5 0.4 0.3 0.9 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.2 0.0 0.0 0.0 0.1 1.6 0.3 0.1 0.1 0.9 0.0 1.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 INPP5F "hSac2, KIAA0966, SAC2" ENSG00000198825 "Inositol polyphosphate-5-phosphatase F" Q9Y2H2 10 119726042-119829147 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 135.3" "Cell type enhanced" "Detected in all" "Excitatory neurons: 79.5;Inhibitory neurons: 130.5;Late spermatids: 88.6;Oligodendrocytes: 70.5" "Cancer enhanced" "Detected in all" "testis cancer: 27.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 91.4;SK-MEL-30: 149.0;SuSa: 181.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042605 Supported Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA042605: AB_10793886" "unprognostic (2.65e-2)" "unprognostic (3.23e-1)" "unprognostic (3.42e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-2)" "unprognostic (1.57e-3)" "unprognostic (2.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (6.46e-2)" "unprognostic (7.78e-2)" "unprognostic (1.02e-1)" "unprognostic (9.91e-2)" "unprognostic (2.96e-2)" "unprognostic (6.21e-2)" 9.9 16.8 53.8 9.9 49.4 4.7 7.6 45.3 63.9 15.7 10.1 15.5 4.6 15.4 22.8 9.3 8.3 6.9 5.9 50.6 135.3 10.5 3.2 9.1 10.7 71.2 57.3 12.3 6.7 7.4 57.1 10.9 75.0 10.9 8.0 32.9 10.8 10.0 11.0 13.7 9.5 13.2 50.3 7.5 8.6 14.8 62.7 7.0 10.5 3.8 13.0 9.2 12.5 55.2 13.5 8.2 91.4 14.3 6.9 10.6 8.5 18.4 9.3 8.4 8.4 12.0 15.2 8.3 7.6 19.7 10.6 14.4 7.9 9.8 11.9 6.0 10.3 6.5 3.9 11.0 13.5 4.4 19.0 9.7 8.6 14.2 13.5 15.7 23.2 6.1 5.7 13.8 20.8 7.0 5.5 15.7 9.2 9.9 12.0 7.0 18.8 2.3 12.5 5.3 6.5 70.2 19.8 7.2 149.0 181.5 4.3 3.4 19.6 9.9 12.2 11.0 17.5 15.2 7.7 4.5 11.0 12.8 32.3 0.9 3.4 1.3 1.0 3.0 1.3 6.7 2.2 1.3 6.2 9.1 2.2 1.1 0.8 3.4 3.6 1.4 5.3 1.9 53.8 49.4 45.3 63.9 50.6 135.3 71.2 57.3 75.0 50.3 62.7 55.2 7.8 6.4 4.8 52.5 21.5 9.1 11.7 7.5 10.2 24.2 6.9 9.5 5.4 1.5 7.8 12.9 16.7 9.3 7.9 15.1 11.7 3.6 58.7 4.3 18.3 8.6 1.2 5.2 79.5 4.5 10.6 7.9 5.1 6.9 2.5 9.7 4.2 3.5 9.9 42.1 130.5 5.6 10.2 6.0 27.8 88.6 5.3 13.1 19.6 34.7 16.3 21.7 6.2 52.8 70.5 6.8 6.6 3.8 4.7 8.2 6.5 24.7 4.0 21.6 6.6 7.8 13.8 22.4 41.0 13.1 10.4 13.3 7.7 19.3 6.5 13.1 INSIG1 "CL-6, MGC1405" ENSG00000186480 "Insulin induced gene 1" O15503 7 155297776-155310235 "Plasma proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 563.4" "Cell type enriched" "Detected in all" 4 "Langerhans cells: 4121.3" "Cancer enriched" "Detected in all" 5 "liver cancer: 142.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "intermediate monocyte: 272.8;non-classical monocyte: 500.8" "Lineage enriched" "Detected in all" 6 "monocytes: 500.8" "Cell line enhanced" "Detected in many" "Karpas-707: 1228.9;RPMI-8226: 605.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071524 Uncertain Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA071524: " "unprognostic (8.11e-2)" "unprognostic (3.22e-1)" "unprognostic (2.91e-1)" "unprognostic (1.47e-1)" "unprognostic (9.23e-2)" "unprognostic (3.83e-2)" "unprognostic (2.05e-2)" "unprognostic (3.06e-1)" "unprognostic (1.60e-2)" "unprognostic (1.52e-1)" "unprognostic (4.64e-2)" "unprognostic (2.12e-1)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.62e-4)" "unprognostic (4.97e-2)" 79.2 37.3 25.3 35.4 36.9 45.5 37.4 47.1 39.1 25.5 58.0 29.8 53.0 19.5 31.8 40.1 17.6 31.6 21.0 30.2 40.9 45.6 563.4 43.2 30.9 61.1 51.7 24.0 111.7 17.4 18.9 34.2 62.8 62.6 26.4 40.5 70.9 11.3 9.0 42.5 35.2 20.3 36.6 19.0 61.1 34.4 36.5 40.4 12.5 12.0 25.3 36.7 23.3 86.3 158.9 29.0 76.8 48.1 200.6 265.5 41.9 12.5 179.1 36.9 242.6 18.1 225.2 104.0 35.7 98.2 282.2 83.9 53.1 92.6 43.3 32.3 155.5 28.6 51.7 0.0 99.0 49.3 448.7 165.6 50.4 281.8 25.8 27.3 49.8 202.8 53.2 1228.9 47.9 82.2 238.7 128.6 80.0 30.4 20.4 43.5 0.2 605.1 291.6 77.8 57.2 45.5 41.6 29.9 67.8 28.7 29.0 162.0 56.3 40.5 11.8 77.2 33.3 296.8 57.4 93.3 177.6 187.2 38.2 21.3 29.7 13.4 49.3 272.8 25.5 46.5 32.8 41.9 78.5 60.2 32.6 36.7 62.6 27.5 500.8 44.7 77.0 85.2 25.3 36.9 47.1 39.1 30.2 40.9 61.1 51.7 62.8 36.6 36.5 86.3 91.4 41.7 121.5 39.8 100.5 140.2 59.4 148.2 74.6 16.5 58.0 31.6 43.6 35.8 114.4 40.5 10.4 47.7 79.0 129.1 17.6 52.0 21.2 30.8 11.6 135.6 126.8 38.3 11.1 140.4 189.0 120.4 57.6 67.4 60.4 18.1 33.2 828.9 46.9 38.7 16.9 91.5 185.1 63.6 4121.3 9.7 15.8 381.0 247.3 7.5 29.6 88.7 34.0 17.1 61.8 53.6 86.6 18.4 100.1 180.4 29.1 9.4 68.3 18.1 19.7 36.3 62.0 33.6 45.0 135.8 155.3 130.4 108.2 20.6 48.0 158.5 INSL4 EPIL ENSG00000120211 "Insulin like 4" Q14641 9 5231419-5235304 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "placenta: 15.9" "Cell type enriched" "Detected in some" 10 "Syncytiotrophoblasts: 3575.7" "Cancer enhanced" "Detected in some" "lung cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "A549: 24.6" HPA065145 Approved Vesicles "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA065145: " "unprognostic (9.77e-2)" "unprognostic (2.02e-1)" "unprognostic (4.66e-1)" "unprognostic (7.74e-2)" 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 24.6 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.4 0.0 2.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 325.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 26.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 38.2 0.0 0.0 0.0 0.0 0.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3575.7 0.0 0.0 0.0 0.0 IQCC FLJ10547 ENSG00000160051 "IQ motif containing C" Q4KMZ1 1 32205671-32208682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 22.2;Spermatogonia: 11.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028602, HPA028686" Approved Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 14: REH - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA028602: AB_10600298, HPA028686: AB_10601985" "unprognostic (1.45e-3)" "unprognostic (4.25e-3)" "unprognostic (2.07e-1)" "unprognostic (1.76e-1)" "unprognostic (2.56e-1)" "unprognostic (4.00e-3)" "unprognostic (7.81e-6)" "prognostic favorable (5.65e-4)" "unprognostic (4.97e-2)" "unprognostic (2.97e-2)" "prognostic favorable (8.23e-5)" "unprognostic (2.00e-1)" "unprognostic (3.28e-1)" "unprognostic (3.12e-3)" "prognostic favorable (3.79e-4)" "unprognostic (4.22e-2)" "unprognostic (1.66e-1)" 1.0 1.8 2.3 1.0 2.7 2.1 2.1 3.6 3.1 1.5 5.3 1.5 0.9 1.5 4.4 1.2 3.5 1.4 1.2 2.6 2.2 1.7 0.8 1.1 1.6 2.1 2.2 2.1 2.4 2.9 3.6 1.1 1.9 1.6 1.5 2.8 1.8 1.7 1.6 2.3 1.2 1.2 2.0 1.3 1.9 8.8 2.4 2.1 3.4 1.3 1.7 1.2 1.3 2.4 6.6 2.3 5.1 4.8 0.9 1.9 3.3 3.7 4.2 7.8 7.2 5.3 5.7 2.3 3.9 1.1 1.3 5.5 5.4 3.3 6.5 3.2 5.6 4.2 5.2 2.3 1.2 4.5 2.7 1.3 3.5 6.9 3.1 2.9 1.6 8.9 7.6 0.5 3.5 4.6 7.7 4.7 3.3 3.6 4.9 10.4 3.1 5.5 2.9 2.3 7.3 2.9 7.4 4.2 4.1 4.7 5.1 4.5 2.2 2.8 5.1 4.1 6.2 2.9 2.1 2.1 3.9 4.2 5.9 0.8 0.3 0.1 1.1 0.4 1.0 2.3 1.2 0.9 0.7 0.8 1.3 0.7 1.1 1.6 0.4 1.0 1.6 0.5 2.3 2.7 3.6 3.1 2.6 2.2 2.1 2.2 1.9 2.0 2.4 2.4 1.7 0.0 2.3 2.0 0.7 0.3 1.0 0.9 1.2 5.4 2.9 1.9 1.6 7.2 0.4 3.7 6.2 1.9 2.1 2.3 3.9 1.8 1.7 8.5 2.0 1.6 3.0 7.0 2.0 1.4 1.6 2.0 1.5 2.1 1.3 2.1 0.0 0.4 0.9 6.7 1.9 4.8 0.0 0.0 1.1 1.8 1.2 0.7 0.0 0.0 1.2 2.6 1.0 0.5 1.3 1.1 1.8 2.6 0.6 0.6 0.9 0.6 3.6 8.6 0.0 2.4 1.7 22.2 11.6 1.1 0.9 1.0 1.3 1.8 2.0 0.3 IRAK1BP1 "AIP70, SIMPL" ENSG00000146243 "Interleukin 1 receptor associated kinase 1 binding protein 1" Q5VVH5 6 78867551-78946440 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 65.4;Excitatory neurons: 73.1;Inhibitory neurons: 57.2;Late spermatids: 52.0;Oligodendrocyte precursor cells: 56.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035742, HPA035743" Uncertain Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA035742: AB_10670119, HPA035743: AB_2674764" "unprognostic (2.62e-1)" "unprognostic (1.38e-2)" "unprognostic (1.32e-1)" "unprognostic (1.19e-1)" "unprognostic (5.82e-2)" "unprognostic (2.12e-1)" "unprognostic (2.38e-3)" "unprognostic (3.93e-2)" "unprognostic (6.55e-2)" "unprognostic (2.34e-2)" "unprognostic (1.32e-2)" "unprognostic (9.88e-2)" "unprognostic (2.81e-2)" "unprognostic (4.64e-2)" "unprognostic (1.82e-1)" "unprognostic (3.39e-2)" "unprognostic (2.58e-1)" 1.5 1.8 0.4 1.0 1.0 5.3 2.4 5.3 2.8 1.8 1.7 1.7 1.1 2.8 4.4 1.2 3.2 1.4 1.7 1.0 0.5 2.9 0.9 2.2 1.8 0.3 0.1 3.1 3.2 3.6 3.4 1.1 0.6 1.8 1.4 5.6 2.6 2.4 1.2 2.3 1.4 2.1 0.0 2.0 3.5 3.9 0.5 3.0 3.3 1.1 1.0 1.5 1.5 1.4 1.1 2.0 3.7 3.5 1.6 3.5 2.1 0.8 2.1 0.8 1.4 1.8 0.9 1.6 0.9 1.9 2.0 2.3 7.1 3.4 1.4 3.7 2.8 1.3 2.4 0.9 2.1 7.6 1.3 2.9 3.3 1.5 1.8 2.7 2.7 4.9 4.0 2.1 1.3 0.6 2.2 3.8 1.8 0.5 2.0 0.4 2.2 1.2 3.6 1.9 5.1 6.0 1.1 1.2 0.9 2.4 2.8 5.1 1.9 1.8 1.3 0.6 2.4 2.5 3.3 2.2 0.6 0.3 2.3 0.9 0.0 0.0 0.3 0.0 0.2 0.3 0.3 0.1 0.1 0.2 0.4 0.4 0.4 0.2 0.1 0.4 0.4 0.1 0.4 1.0 5.3 2.8 1.0 0.5 0.3 0.1 0.6 0.0 0.5 1.4 6.1 19.2 7.8 39.2 3.3 2.5 5.3 3.9 10.8 10.3 5.2 8.5 13.6 8.6 9.3 3.7 33.3 3.6 3.5 1.0 9.8 5.5 65.4 20.5 11.5 5.5 6.6 7.8 73.1 6.0 0.8 5.8 5.1 3.6 0.0 11.6 5.0 2.4 1.6 5.0 57.2 2.7 0.0 1.3 0.9 52.0 10.5 1.6 0.0 22.5 0.8 12.9 2.1 56.3 33.6 3.3 1.0 8.2 3.1 1.2 0.6 11.8 21.5 17.9 13.1 8.2 8.1 42.3 15.2 6.3 2.6 0.8 2.5 11.1 3.2 2.8 IRAK2 ENSG00000134070 "Interleukin 1 receptor associated kinase 2" O43187 3 10164919-10243745 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 43.7;Oligodendrocytes: 34.3;Prostatic glandular cells: 23.4;Urothelial cells: 30.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 33.2;BJ hTERT+: 35.2;CAPAN-2: 35.6;GAMG: 62.6;RT4: 49.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013483, HPA050520" Uncertain Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 41: Macrophages - Immune response" Vesicles "CAB013483: , HPA050520: AB_2681154" "unprognostic (1.31e-1)" "unprognostic (2.04e-2)" "unprognostic (1.46e-2)" "unprognostic (4.61e-3)" "unprognostic (8.71e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (8.35e-4)" "unprognostic (1.89e-2)" "unprognostic (8.01e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.24e-1)" "unprognostic (3.10e-2)" "unprognostic (7.22e-2)" "unprognostic (4.38e-2)" "unprognostic (3.91e-2)" "prognostic favorable (6.60e-5)" 6.4 3.6 4.0 6.0 3.9 23.3 4.6 3.9 8.0 2.9 1.7 2.1 2.0 2.0 0.7 7.2 1.8 4.4 1.9 3.2 5.1 3.4 10.8 10.4 3.8 5.1 4.1 1.0 1.9 1.0 1.2 2.2 5.6 3.3 1.7 1.5 3.6 1.8 17.0 5.2 5.4 1.4 3.4 4.5 3.4 1.3 4.2 3.9 3.1 4.3 11.5 16.1 4.5 8.0 2.7 7.6 0.3 1.0 8.1 6.7 33.2 2.9 35.2 4.7 4.5 3.6 35.6 0.1 0.9 4.3 62.6 0.8 0.8 9.0 6.3 2.3 2.5 0.8 1.7 9.9 3.9 0.0 1.1 4.1 1.5 17.3 22.4 12.4 9.7 0.3 1.8 10.7 5.7 0.1 0.0 1.8 0.3 4.2 7.5 1.7 0.0 0.6 10.3 49.2 0.5 0.3 3.3 0.1 0.3 0.8 0.8 1.7 10.1 10.7 0.9 6.5 7.0 3.6 11.3 2.1 22.9 4.7 1.9 0.2 1.0 0.1 5.8 0.7 6.0 4.2 1.7 3.3 1.0 3.2 1.2 3.0 2.1 7.4 0.2 0.0 0.7 2.2 4.0 3.9 3.9 8.0 3.2 5.1 5.1 4.1 5.6 3.4 4.2 8.0 3.9 0.0 4.1 1.6 8.3 8.0 20.8 9.9 5.2 0.9 1.6 1.3 2.0 0.0 6.1 0.0 0.0 0.2 3.8 1.3 0.0 9.8 4.1 4.3 2.4 12.3 0.0 0.0 6.3 4.2 0.7 4.3 7.7 16.7 0.0 0.1 0.7 4.8 3.4 0.0 7.0 0.7 4.1 2.9 43.7 1.5 0.9 20.9 5.4 13.1 1.9 2.1 7.2 7.1 34.3 15.7 0.3 0.0 7.4 23.4 2.6 1.1 1.3 0.0 0.0 4.2 2.0 0.7 0.9 4.7 7.4 1.0 3.9 0.2 0.5 30.4 IRAK3 IRAK-M ENSG00000090376 "Interleukin 1 receptor associated kinase 3" Q9Y616 12 66189195-66254622 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.1" "Cell type enhanced" "Detected in many" "Adipocytes: 83.3;Kupffer cells: 123.0;Macrophages: 126.3;Microglial cells: 114.3;monocytes: 96.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 12.7;classical monocyte: 23.4;intermediate monocyte: 24.2;myeloid DC: 11.5;neutrophil: 12.9;non-classical monocyte: 42.0" "Group enriched" "Detected in many" 12 "dendritic cells: 11.5;granulocytes: 12.9;monocytes: 42.0" "Cell line enhanced" "Detected in many" "ASC diff: 25.9;ASC TERT1: 21.1;HEL: 22.9;HL-60: 30.8;NB-4: 25.1;THP-1: 37.3;U-937: 26.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043097 Approved Approved Vesicles "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA043097: AB_10795612" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-1)" "unprognostic (7.56e-3)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (7.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.95e-2)" "unprognostic (8.52e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (5.58e-2)" "unprognostic (4.64e-2)" "unprognostic (3.41e-2)" "unprognostic (3.23e-2)" 18.7 3.8 3.7 12.4 4.1 78.1 11.6 4.1 7.5 9.3 5.4 4.6 1.3 4.0 3.0 3.8 8.0 6.9 7.9 3.2 4.7 3.5 2.8 19.0 4.1 5.6 5.7 3.2 2.5 0.9 8.9 6.8 6.5 5.3 2.8 0.4 6.2 5.6 2.6 3.4 5.6 5.4 5.0 27.5 6.9 1.8 5.6 2.7 5.0 4.6 3.9 8.4 6.6 5.1 0.0 0.0 0.4 0.0 25.9 21.1 0.0 2.9 0.0 1.5 2.3 0.0 2.2 0.0 1.4 5.3 0.0 0.0 3.2 0.0 1.3 0.0 0.0 22.9 1.4 0.0 13.4 30.8 4.0 13.5 0.1 1.2 0.0 0.0 7.6 0.0 0.0 0.0 1.0 0.0 0.0 25.1 1.3 0.0 0.0 0.0 6.4 0.0 0.1 3.3 0.1 0.0 11.6 0.0 1.2 0.1 0.1 37.3 8.2 0.0 0.0 0.0 0.0 0.9 0.2 2.2 0.0 26.8 0.0 12.7 23.4 4.3 0.0 24.2 0.0 0.1 0.0 0.0 11.5 0.7 0.0 0.0 12.9 1.8 42.0 0.1 0.6 7.3 3.7 4.1 4.1 7.5 3.2 4.7 5.6 5.7 6.5 5.0 5.6 5.1 83.3 9.6 19.4 1.3 2.3 1.5 4.8 27.5 6.2 0.3 2.5 1.8 2.8 0.0 46.9 3.7 0.0 0.2 14.8 0.5 0.0 0.6 6.4 0.5 7.5 38.5 0.0 9.7 0.4 1.2 0.4 22.3 18.3 0.5 27.3 0.5 36.4 1.2 9.4 0.0 5.6 1.1 36.7 123.0 12.1 5.3 7.2 126.3 5.4 114.3 96.9 0.2 3.1 2.0 0.6 4.9 0.1 11.3 9.1 1.6 0.0 0.2 35.1 0.1 0.0 18.1 10.2 0.8 1.8 1.2 1.3 0.3 3.5 12.5 0.7 2.5 IRGQ "FKSG27, IRGQ1" ENSG00000167378 "Immunity related GTPase Q" Q8WZA9 19 43584369-43596135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043254, HPA050338" Approved Approved Vesicles NA NA 45000 "Cluster 17: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA043254: AB_10794178, HPA050338: AB_2681094" "unprognostic (1.98e-1)" "prognostic favorable (5.17e-4)" "unprognostic (2.55e-1)" "unprognostic (2.07e-3)" "unprognostic (9.87e-2)" "unprognostic (3.20e-3)" "prognostic unfavorable (9.60e-4)" "unprognostic (1.96e-2)" "unprognostic (3.98e-1)" "unprognostic (7.48e-2)" "prognostic favorable (3.57e-5)" "unprognostic (9.24e-2)" "prognostic favorable (3.92e-4)" "unprognostic (2.82e-1)" "unprognostic (7.91e-2)" "unprognostic (5.18e-2)" "unprognostic (4.65e-2)" 2.3 3.0 6.7 1.5 6.6 7.0 2.4 2.3 8.3 3.6 0.0 2.9 1.5 3.4 1.5 2.8 3.3 1.2 4.5 8.0 4.5 2.5 2.4 3.7 1.0 12.7 5.6 4.3 2.7 2.2 4.2 1.4 5.2 2.8 1.3 3.2 3.1 1.6 6.0 2.9 2.0 1.6 1.5 2.3 2.7 2.2 7.4 1.0 2.6 3.9 1.5 2.7 2.9 3.6 2.6 4.3 3.5 7.1 3.7 2.6 3.5 2.3 1.4 2.6 2.6 3.3 1.5 1.6 3.6 2.8 2.5 3.7 3.3 1.8 1.6 3.1 2.4 2.3 6.0 2.7 2.3 3.1 3.2 2.6 3.6 3.3 1.8 2.8 3.3 2.7 3.4 3.3 2.5 2.2 3.9 2.2 1.8 0.8 2.3 7.2 3.2 1.3 2.1 5.4 6.7 6.0 6.3 6.4 1.8 3.7 4.2 2.8 5.2 8.7 6.3 2.2 3.2 3.4 3.1 2.8 5.2 1.4 7.0 2.3 0.5 0.3 0.2 0.4 0.2 0.2 0.2 0.2 0.3 0.3 0.3 0.2 1.0 0.3 0.5 0.5 0.2 0.3 6.7 6.6 2.3 8.3 8.0 4.5 12.7 5.6 5.2 1.5 7.4 3.6 5.3 12.8 18.1 9.8 5.4 6.5 10.9 8.8 8.6 17.1 16.5 11.0 28.8 17.2 10.5 3.7 27.1 5.8 5.0 15.7 1.9 12.6 7.4 12.6 14.5 10.9 36.0 4.4 11.7 13.0 3.8 8.0 9.7 18.6 12.7 18.3 8.2 14.3 8.6 20.2 12.3 14.4 2.0 11.1 9.9 5.7 3.1 12.0 5.4 4.7 7.2 11.9 0.0 9.0 9.1 17.8 8.6 10.5 5.9 18.5 10.5 10.9 7.0 20.8 0.0 13.8 9.3 2.8 2.6 12.5 6.7 7.7 5.3 9.6 11.8 16.4 IST1 "CHMP8, KIAA0174" ENSG00000182149 "IST1 factor associated with ESCRT-III" P53990 16 71845996-71931199 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041802, HPA054532" Approved Supported Vesicles NA NA 270000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041802: AB_10794491, HPA054532: AB_2682517" "unprognostic (2.15e-1)" "unprognostic (2.80e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-3)" "unprognostic (2.04e-2)" "unprognostic (3.13e-3)" "unprognostic (2.11e-2)" "unprognostic (4.49e-2)" "unprognostic (3.96e-2)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (1.02e-1)" "prognostic favorable (4.55e-4)" "unprognostic (1.64e-2)" "unprognostic (7.88e-3)" "unprognostic (8.43e-3)" "prognostic favorable (8.88e-4)" 47.7 44.1 43.2 38.8 49.7 81.0 50.5 46.2 50.6 49.0 43.9 68.3 52.4 55.9 42.4 50.5 61.4 46.8 50.4 42.9 45.3 68.7 37.9 50.0 64.3 47.2 47.6 60.0 46.9 90.4 57.2 60.1 47.1 45.7 62.9 32.4 52.0 45.8 64.1 52.5 52.0 60.8 45.5 50.6 52.5 47.4 46.1 62.2 59.4 80.8 81.6 53.0 44.3 53.8 57.0 81.9 113.3 73.2 110.7 77.9 95.7 70.0 87.1 95.2 98.9 90.1 77.1 80.5 84.2 81.2 67.7 83.8 112.0 74.2 120.4 53.7 54.1 68.1 46.8 146.9 83.8 66.9 91.9 92.7 100.8 85.5 81.6 94.8 120.6 74.8 94.5 28.7 99.5 94.9 87.4 55.6 129.7 92.7 50.6 135.7 62.0 99.1 78.5 81.8 85.0 63.3 77.2 40.3 63.9 138.2 73.7 82.2 60.7 71.8 70.9 44.5 55.9 75.0 145.5 226.7 60.7 59.2 88.6 234.9 195.1 243.5 158.7 185.4 172.6 179.1 150.6 166.9 180.1 178.5 159.6 150.1 300.0 193.7 185.1 124.9 244.9 293.9 43.2 49.7 46.2 50.6 42.9 45.3 47.2 47.6 47.1 45.5 46.1 53.8 59.7 48.1 51.8 39.8 57.1 70.1 41.2 49.8 39.9 29.2 69.1 50.0 43.9 60.1 48.1 46.0 25.0 56.7 68.4 130.6 35.2 47.1 18.4 50.0 52.8 55.4 75.4 30.7 35.5 41.7 44.3 48.1 42.3 70.1 61.4 55.1 61.1 40.8 53.4 21.9 41.6 76.3 46.8 81.1 73.8 22.5 41.0 57.2 42.7 38.4 75.9 22.2 51.5 34.2 59.7 58.1 88.4 47.8 45.2 51.5 82.2 52.4 56.2 30.3 59.2 45.3 44.4 52.4 57.3 34.4 70.0 65.7 51.8 31.3 57.6 66.4 ITIH1 "H1P, IATIH, ITIH" ENSG00000055957 "Inter-alpha-trypsin inhibitor heavy chain 1" P19827 3 52777595-52792068 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 782 "liver: 1504.9" "Cell type enriched" "Detected in some" 34 "Hepatocytes: 1087.0" "Cancer enriched" "Detected in some" 598 "liver cancer: 329.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 5.3;Hep G2: 1.7;HL-60: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041639, HPA042049" Approved Approved Vesicles "Secreted to blood" NA NA 4490000 59000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA041639: AB_10796349, HPA042049: AB_10797379" "unprognostic (1.87e-4)" "unprognostic (1.31e-3)" "unprognostic (2.38e-1)" "unprognostic (8.55e-2)" "unprognostic (1.03e-1)" "unprognostic (2.64e-3)" "prognostic favorable (1.89e-5)" "unprognostic (2.27e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (2.91e-2)" "unprognostic (8.45e-2)" "unprognostic (4.53e-4)" "unprognostic (4.02e-3)" "unprognostic (5.70e-3)" "unprognostic (2.08e-1)" "unprognostic (2.24e-2)" 0.8 0.3 0.0 0.5 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.4 0.0 0.0 0.2 1504.9 0.1 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 1.9 0.4 0.4 0.0 0.4 0.0 0.1 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.1 0.0 29.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 18.5 1087.0 0.1 0.0 0.0 0.0 0.0 20.2 0.0 1.7 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.1 ITIH4 "H4P, IHRP, ITIHL1" ENSG00000055955 "Inter-alpha-trypsin inhibitor heavy chain 4" Q14624 3 52812962-52830688 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 38 "liver: 1863.4" "Group enriched" "Detected in many" 5 "Early spermatids: 119.2;Hepatocytes: 134.6;Late spermatids: 126.5" "Cancer enriched" "Detected in single" 27 "liver cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.4;JURKAT: 2.0;U-266/70: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001835, HPA003948, CAB072872" Enhanced Approved Vesicles "Secreted to blood" NA NA 3060000 58000000000 "Cluster 15: NK-cells - Transcription" "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB072872: AB_2665724, HPA001835: AB_1079432, HPA003948: AB_1079433" "unprognostic (6.08e-2)" "unprognostic (4.45e-2)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "unprognostic (2.64e-1)" "unprognostic (1.96e-1)" "unprognostic (5.86e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-2)" "unprognostic (1.02e-1)" "unprognostic (2.47e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-14)" "unprognostic (1.71e-3)" "unprognostic (2.96e-2)" "unprognostic (1.52e-1)" "unprognostic (4.21e-5)" 4.2 18.5 4.1 1.2 4.2 10.0 3.0 3.7 5.0 4.2 3.5 3.6 1.0 2.9 1.7 1.4 3.8 1.1 3.2 3.9 3.6 5.4 1863.4 4.9 1.7 3.9 3.8 2.4 48.9 0.1 4.3 0.7 3.9 4.0 1.0 3.3 2.1 1.8 40.3 2.5 3.4 1.5 3.6 7.4 3.9 1.8 3.8 2.2 5.2 2.8 1.2 5.3 3.3 3.9 0.0 0.1 0.4 0.9 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.2 0.1 0.4 0.0 0.0 0.2 2.4 0.1 1.0 0.0 1.2 0.4 1.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 2.0 0.3 0.8 0.0 0.1 0.2 0.3 0.4 0.1 0.0 0.8 0.3 0.0 0.2 0.3 0.0 0.4 0.3 0.0 0.1 0.4 0.5 0.3 0.1 0.0 0.4 0.4 0.0 3.0 1.4 0.2 0.0 0.3 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 4.1 4.2 3.7 5.0 3.9 3.6 3.9 3.8 3.9 3.6 3.8 3.9 0.7 0.0 1.1 22.5 0.9 0.8 0.3 0.3 0.0 10.0 0.6 1.3 1.1 2.8 0.8 0.0 12.5 0.0 0.4 0.1 0.0 0.3 119.2 0.7 0.7 0.8 0.0 8.4 11.6 2.6 0.0 0.6 1.1 0.4 0.0 2.7 2.5 134.6 0.5 5.0 8.6 0.2 0.0 2.2 1.0 126.5 1.2 1.3 0.0 5.6 1.9 2.3 2.1 3.0 3.1 2.3 0.5 1.9 0.7 0.2 0.0 0.3 0.3 6.0 6.6 6.2 2.4 1.3 1.5 0.0 0.3 0.3 1.2 3.2 0.1 0.1 ITPR1 "ACV, Insp3r1, IP3R1, PPP1R94, SCA15, SCA16, SCA29" ENSG00000150995 "Inositol 1,4,5-trisphosphate receptor type 1" Q14643 3 4493345-4847840 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Mental retardation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 290.2;Inhibitory neurons: 183.1;Microglial cells: 84.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 49.9" "Immune cell enhanced" "Detected in many" "naive B-cell: 13.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 76.4;HEL: 41.1;HeLa: 74.9;HMC-1: 40.0;U-87 MG: 56.7" "Region enhanced" "Detected in all" "cerebellum: 697.2" "Region enhanced" "Detected in all" "cerebellum: 208.8" "HPA014765, HPA016487" Approved Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA014765: AB_1851843, HPA016487: AB_1851842" "unprognostic (1.92e-1)" "unprognostic (5.04e-2)" "unprognostic (1.34e-1)" "unprognostic (1.75e-1)" "unprognostic (2.16e-2)" "unprognostic (3.61e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.17e-2)" "unprognostic (1.92e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.40e-1)" 10.6 12.0 1.8 11.8 12.0 7.2 17.3 49.9 20.1 11.5 15.6 19.5 4.5 36.5 10.0 10.6 27.1 14.1 10.1 5.9 0.0 13.9 3.9 13.7 11.2 0.0 0.5 25.3 6.7 45.3 16.0 8.0 0.0 21.7 6.3 3.9 16.1 27.9 3.0 5.0 11.5 24.5 0.0 9.2 11.1 4.5 0.0 10.3 31.7 5.3 10.5 27.9 11.8 6.1 0.4 4.1 1.0 3.0 27.7 1.9 11.8 0.9 0.5 1.3 0.8 1.3 1.2 14.5 0.6 1.9 6.5 0.1 2.2 2.6 2.1 76.4 3.2 41.1 74.9 3.5 27.4 17.7 40.0 9.2 4.0 5.8 1.1 7.6 7.2 8.4 7.9 13.9 3.7 1.8 7.2 3.0 2.1 0.5 9.7 4.2 1.0 1.1 1.7 5.5 0.7 19.5 5.4 4.3 4.3 0.9 2.6 20.6 13.5 1.8 4.3 3.7 2.3 17.7 12.0 9.6 56.7 17.0 2.7 5.8 2.0 1.5 2.3 0.9 1.7 6.7 1.6 1.6 2.2 13.4 2.7 1.6 1.8 1.8 0.9 4.7 1.4 1.1 1.8 12.0 49.9 20.1 5.9 0.0 0.0 0.5 0.0 0.0 0.0 6.1 30.1 0.0 31.4 24.8 49.7 3.8 6.1 6.3 11.4 4.0 40.0 29.7 8.0 2.8 11.2 9.2 0.0 0.5 17.8 0.3 3.9 2.4 5.4 9.1 11.9 31.2 3.5 8.4 290.2 5.1 0.5 21.5 20.4 12.7 26.5 22.6 36.0 2.0 4.7 1.7 183.1 1.3 2.0 12.9 17.4 7.9 30.1 23.9 7.2 84.3 14.2 4.3 6.2 25.1 12.7 1.5 1.2 52.6 8.8 5.4 0.3 3.9 13.1 1.5 39.5 8.8 28.2 1.5 2.9 4.9 3.1 1.0 25.7 22.0 0.8 3.3 ITPR3 IP3R3 ENSG00000096433 "Inositol 1,4,5-trisphosphate receptor type 3" Q14573 6 33620365-33696574 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 123.0;Gastric mucus-secreting cells: 127.4;Late spermatids: 220.4;Pancreatic endocrine cells: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 164.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA003915, HPA064704" Approved Uncertain Vesicles No Yes "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA003915: AB_1851845, HPA064704: " "unprognostic (2.57e-1)" "unprognostic (2.81e-2)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (5.40e-2)" "unprognostic (1.24e-1)" "unprognostic (2.08e-2)" "unprognostic (6.14e-2)" "unprognostic (3.35e-1)" "unprognostic (3.08e-2)" "unprognostic (4.14e-3)" "unprognostic (1.88e-1)" "unprognostic (6.44e-3)" "unprognostic (5.01e-2)" "unprognostic (1.74e-1)" "unprognostic (8.89e-2)" "unprognostic (2.43e-2)" 16.3 11.4 5.5 17.0 5.0 6.1 14.6 3.8 5.3 18.0 3.7 26.2 29.1 8.5 13.1 18.1 14.0 15.3 15.0 3.8 3.9 16.4 2.2 30.6 20.4 5.6 5.0 13.5 11.3 2.8 7.4 4.3 5.2 13.9 18.4 0.8 18.5 11.2 4.5 58.9 35.1 4.7 4.7 39.8 41.5 15.4 7.0 14.3 54.0 5.1 21.0 12.1 24.0 3.9 73.7 34.0 6.3 0.3 6.2 19.3 40.9 24.8 62.8 30.5 27.4 46.7 55.9 62.6 26.1 17.9 76.1 70.9 28.6 66.7 15.7 36.8 24.0 0.1 102.6 52.0 14.1 11.3 7.9 14.0 59.2 76.7 164.7 66.5 52.1 24.5 25.0 19.7 33.3 35.0 19.0 6.4 6.2 55.8 49.4 29.0 0.1 37.1 107.6 50.9 57.3 2.1 42.8 61.6 60.2 6.9 21.2 5.9 71.8 41.1 20.1 53.1 55.2 13.5 14.3 29.4 32.8 16.6 24.1 0.8 0.0 0.0 0.8 0.0 0.6 0.4 0.4 0.5 0.0 0.6 0.4 0.5 0.0 0.0 0.0 0.0 0.7 0.2 5.5 5.0 3.8 5.3 3.8 3.9 5.6 5.0 5.2 4.7 7.0 3.9 12.4 48.1 58.9 0.3 13.5 26.5 10.9 27.9 18.2 1.5 9.3 9.9 2.7 12.8 20.2 31.3 0.0 0.3 10.9 52.9 0.0 28.4 123.0 19.1 9.1 18.2 23.9 6.6 1.1 30.2 6.3 9.2 127.4 43.1 0.0 0.2 12.5 0.4 0.5 0.0 1.6 41.6 10.2 0.6 6.9 220.4 23.3 2.6 12.4 23.4 3.2 0.4 4.1 0.5 0.4 89.7 41.6 13.9 18.7 20.5 45.9 0.2 12.1 1.2 6.6 3.9 3.3 1.6 3.2 14.5 25.4 0.5 13.1 5.8 35.6 20.7 ITPRIP "bA127L20.2, DANGER, KIAA1754" ENSG00000148841 "Inositol 1,4,5-trisphosphate receptor interacting protein" Q8IWB1 10 104309698-104338465 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 203.2" "Cell type enhanced" "Detected in many" "Adipocytes: 98.0;Hepatic stellate cells: 82.1;Squamous epithelial cells: 108.4;Suprabasal keratinocytes: 72.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 103.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043626 Uncertain Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA043626: AB_10963078" "unprognostic (2.45e-2)" "unprognostic (3.06e-1)" "unprognostic (1.59e-2)" "unprognostic (3.22e-2)" "unprognostic (1.08e-2)" "unprognostic (4.20e-1)" "unprognostic (7.87e-2)" "prognostic unfavorable (3.59e-4)" "unprognostic (9.74e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (4.00e-2)" "unprognostic (5.37e-3)" "unprognostic (1.01e-3)" "unprognostic (2.65e-1)" "unprognostic (2.75e-1)" "unprognostic (2.11e-3)" 36.3 13.7 5.7 16.9 5.9 203.2 25.4 5.3 10.5 31.6 15.5 13.6 3.1 16.3 3.7 52.9 15.1 21.2 72.5 5.5 6.6 18.0 13.3 38.5 10.4 8.0 6.3 29.1 9.4 8.0 15.9 26.8 6.4 14.0 5.0 1.7 14.1 9.0 10.1 66.3 8.8 18.2 7.0 12.6 12.3 7.4 8.0 12.8 21.1 10.4 11.9 23.7 43.5 7.7 6.4 16.1 19.2 8.6 32.8 31.4 10.9 35.0 75.9 25.8 32.0 1.2 2.8 11.2 7.7 22.5 51.2 20.7 6.5 17.4 26.6 9.6 7.6 6.6 24.6 4.9 64.3 15.9 12.3 29.2 103.5 53.8 42.8 29.9 48.7 11.4 28.4 21.5 32.0 2.7 3.1 17.0 14.3 2.2 17.9 14.3 9.9 6.8 10.6 2.8 10.7 7.0 6.7 7.8 16.0 11.6 0.6 11.8 82.7 51.9 13.6 34.5 34.5 7.8 9.8 7.3 38.0 27.9 24.8 4.4 9.5 14.0 4.5 5.8 4.5 2.5 2.7 2.6 6.2 2.8 3.2 2.9 30.6 5.0 5.8 4.2 2.3 21.3 5.7 5.9 5.3 10.5 5.5 6.6 8.0 6.3 6.4 7.0 8.0 7.7 98.0 3.2 8.3 1.3 9.0 37.9 15.3 13.2 44.3 0.0 3.0 2.4 7.8 1.5 9.0 3.7 0.0 7.3 37.0 1.7 0.0 3.7 6.3 11.7 10.0 42.5 0.0 8.8 0.6 2.4 22.6 15.5 3.6 46.7 20.3 3.6 82.1 2.3 10.8 0.0 0.4 2.6 2.0 17.2 20.6 1.6 5.0 28.1 8.8 6.5 7.0 3.8 10.3 0.5 0.9 3.0 0.5 5.7 13.6 5.8 0.2 0.5 5.2 0.6 13.1 6.3 14.7 8.1 1.8 108.4 72.7 5.1 23.8 4.4 1.1 20.5 JAGN1 "FLJ14602, GL009" ENSG00000171135 "Jagunal homolog 1" Q8N5M9 3 9890574-9894349 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067610 Approved Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA067610: " "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (1.86e-3)" "unprognostic (1.97e-2)" "unprognostic (1.77e-1)" "unprognostic (1.95e-1)" "unprognostic (2.92e-3)" "unprognostic (1.57e-1)" "unprognostic (2.37e-2)" "unprognostic (6.36e-3)" "unprognostic (9.93e-3)" "unprognostic (2.70e-1)" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" "unprognostic (1.29e-1)" "unprognostic (3.65e-2)" "unprognostic (2.49e-1)" 29.6 43.5 21.3 15.7 22.3 12.1 26.6 23.8 28.9 21.9 24.6 26.3 27.0 23.4 39.7 19.4 25.7 16.4 22.9 21.6 23.1 30.1 62.6 17.4 19.2 22.5 22.3 25.5 40.2 31.5 17.8 20.6 22.5 20.9 30.2 19.9 24.0 20.8 36.1 27.6 26.4 20.5 22.9 17.6 30.8 14.1 22.7 24.0 17.8 30.1 23.6 23.0 21.0 23.6 32.7 54.0 39.8 23.9 116.9 121.5 128.3 43.8 65.2 49.4 49.6 40.6 43.1 51.4 19.6 44.2 54.0 28.1 63.1 59.5 48.9 38.4 65.7 62.4 55.7 73.7 99.4 45.6 37.3 115.3 89.4 63.6 73.2 51.0 47.0 45.8 65.0 34.5 59.2 99.0 37.8 80.5 50.1 65.3 74.3 31.0 32.5 64.4 73.3 45.9 25.0 46.4 29.6 31.8 58.1 35.8 50.4 56.8 39.9 26.2 28.1 29.3 35.4 60.2 94.5 60.7 33.1 55.7 44.9 100.9 61.8 31.1 48.1 48.6 50.5 52.5 46.8 45.9 57.4 53.3 50.9 48.0 24.9 51.9 37.9 58.1 54.7 67.9 21.3 22.3 23.8 28.9 21.6 23.1 22.5 22.3 22.5 22.9 22.7 23.6 28.7 32.1 17.5 5.2 38.6 27.5 47.8 84.1 30.7 27.3 53.0 58.8 14.1 55.8 43.5 38.6 10.4 74.7 30.8 49.5 21.5 80.6 3.2 33.0 33.5 36.3 25.8 30.9 4.8 98.1 80.1 37.9 30.1 22.9 8.2 36.5 42.8 52.4 55.8 23.5 5.7 55.2 59.0 40.7 22.5 6.8 39.4 29.8 37.4 4.7 75.3 52.3 50.4 8.0 8.0 73.5 55.7 38.7 35.3 66.2 114.2 55.9 40.6 23.3 46.0 31.6 31.7 66.0 51.2 35.8 36.8 52.9 31.3 48.8 58.3 39.2 JTB "hJT, PAR" ENSG00000143543 "Jumping translocation breakpoint" O76095 1 153974269-153977674 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006514 Approved Uncertain Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA006514: AB_1079164" "unprognostic (1.33e-1)" "unprognostic (1.77e-1)" "unprognostic (8.01e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (3.40e-1)" "unprognostic (5.66e-3)" "unprognostic (8.62e-3)" "unprognostic (5.60e-2)" "prognostic favorable (7.87e-4)" "unprognostic (1.00e-3)" "unprognostic (8.16e-2)" "prognostic unfavorable (6.65e-9)" "unprognostic (1.36e-1)" "unprognostic (4.25e-1)" "unprognostic (5.48e-2)" "unprognostic (2.58e-3)" 105.6 119.8 121.1 60.4 125.1 127.0 103.0 122.3 153.9 99.8 149.0 117.8 89.5 89.8 96.3 110.8 91.8 53.7 121.0 120.8 122.2 135.4 207.1 110.2 80.4 125.4 122.2 98.4 232.2 93.9 185.9 68.0 121.5 131.0 86.7 49.8 162.0 68.0 166.5 99.8 115.3 50.1 123.3 136.9 164.8 46.6 126.6 77.7 120.5 82.7 80.2 96.3 89.4 123.4 206.3 139.4 57.9 108.0 189.0 116.2 163.5 144.6 142.3 95.9 96.0 135.3 166.7 193.7 198.7 171.8 59.1 181.0 151.0 113.2 78.1 180.5 296.0 112.5 158.4 139.0 198.1 221.4 165.7 110.4 210.4 101.1 119.1 131.0 115.4 223.7 169.3 139.2 68.4 359.6 161.5 280.5 125.8 402.1 239.1 163.9 79.3 393.1 123.7 110.9 158.4 158.8 115.3 332.7 208.4 107.4 209.1 316.4 89.6 46.5 80.4 144.4 189.0 201.8 244.7 211.3 114.5 209.6 103.7 98.7 119.5 173.2 74.7 86.4 90.9 143.5 104.0 118.7 88.9 139.9 107.0 85.6 104.9 85.3 96.5 147.4 98.5 97.7 121.1 125.1 122.3 153.9 120.8 122.2 125.4 122.2 121.5 123.3 126.6 123.4 127.7 80.1 101.1 15.7 184.3 156.8 177.4 227.5 104.7 56.6 253.4 207.3 96.5 213.1 171.4 99.3 22.9 308.8 237.3 273.4 258.2 251.9 7.1 145.0 95.3 120.4 212.0 178.8 26.3 411.8 405.0 155.6 149.9 125.9 82.5 113.2 125.7 341.3 289.1 57.2 24.0 423.4 213.6 235.8 185.8 20.1 151.6 176.3 170.7 19.7 207.9 140.4 257.5 19.6 29.1 274.1 302.2 123.4 344.8 346.0 368.2 274.1 138.2 60.2 105.2 105.3 114.0 58.9 71.5 173.4 190.2 289.5 173.6 136.6 315.2 304.0 KCNG1 "K13, KCNG, kH2, Kv6.1" ENSG00000026559 "Potassium voltage-gated channel modifier subfamily G member 1" Q9UIX4 20 51003656-51023107 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.8;endometrium 1: 87.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 53.7;Granulosa cells: 34.0;Syncytiotrophoblasts: 97.0" "Cancer enhanced" "Detected in many" "urothelial cancer: 8.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 20 "naive B-cell: 7.1" "Lineage enriched" "Detected in single" 71 "B-cells: 7.1" "Cell line enhanced" "Detected in many" "hTCEpi: 53.5;U-138 MG: 40.4;WM-115: 34.6" "Group enriched" "Detected in many" 5 "amygdala: 20.6;basal ganglia: 19.1;cerebral cortex: 14.9;hippocampal formation: 18.1;white matter: 9.1" "Group enriched" "Detected in all" 5 "amygdala: 12.6;basal ganglia: 11.1;cerebral cortex: 22.4;hippocampal formation: 16.8" "HPA039530, HPA040024" Approved Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA039530: AB_10795144, HPA040024: AB_10796338" "unprognostic (1.19e-1)" "unprognostic (4.47e-2)" "unprognostic (8.70e-2)" "unprognostic (3.49e-2)" "unprognostic (4.07e-2)" "unprognostic (5.05e-4)" "unprognostic (2.53e-2)" "unprognostic (3.89e-3)" "unprognostic (3.64e-2)" "unprognostic (3.43e-2)" "unprognostic (8.74e-2)" "unprognostic (8.89e-2)" "unprognostic (1.83e-9)" "unprognostic (1.52e-1)" "unprognostic (7.42e-2)" "unprognostic (1.60e-1)" "unprognostic (1.02e-2)" 0.4 3.0 17.3 2.2 26.7 0.0 0.4 0.0 21.7 17.9 0.1 5.0 0.2 87.4 0.8 6.7 19.2 0.9 1.3 14.9 0.6 0.5 0.2 0.3 2.2 28.9 46.8 0.7 2.7 4.1 0.8 7.1 3.2 5.6 0.8 0.1 2.2 12.8 0.0 0.5 5.3 4.1 1.0 2.7 0.7 9.5 1.2 0.2 0.2 0.0 0.9 3.4 6.2 1.1 0.9 3.6 2.7 13.3 1.5 3.4 0.2 11.6 0.1 6.7 5.3 0.2 0.2 0.0 7.1 3.5 18.8 3.4 1.7 3.5 6.9 0.4 4.7 0.0 13.6 0.0 23.2 0.0 0.4 6.8 53.5 25.7 26.1 1.3 1.8 0.1 0.2 0.0 0.6 13.4 0.0 0.4 13.7 0.0 25.0 0.0 0.0 0.0 0.0 4.1 3.9 15.0 25.5 29.3 19.9 4.3 2.1 1.9 0.7 40.4 23.9 0.3 3.4 0.1 0.0 0.0 11.8 1.0 34.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17.3 26.7 0.0 21.7 14.9 0.6 28.9 46.8 3.2 1.0 1.2 1.1 0.2 3.2 1.1 0.3 10.5 1.1 11.0 0.6 13.6 0.3 1.1 2.3 1.1 7.2 0.9 0.0 0.0 53.7 0.0 7.5 0.0 2.6 18.2 9.3 2.0 1.2 0.0 0.0 2.0 0.0 2.7 1.5 0.5 15.9 0.0 34.0 0.4 0.3 3.3 1.7 2.2 0.6 0.0 0.0 0.3 20.3 1.5 0.3 0.0 1.0 0.0 0.2 1.0 0.0 0.6 0.2 3.4 4.1 0.0 18.1 12.8 0.1 0.9 0.2 0.0 1.1 7.1 12.7 0.7 5.4 0.3 97.0 0.4 0.3 0.4 9.9 KCNH1 "eag, eag1, h-eag, hEAG, Kv10.1" ENSG00000143473 "Potassium voltage-gated channel subfamily H member 1" O95259 1 210676823-211134165 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 533.5;Inhibitory neurons: 261.0;Oligodendrocytes: 116.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 6.2;RH-30: 10.1;RPTEC TERT1: 6.0;SH-SY5Y: 12.9;SK-MEL-30: 12.9;T-47d: 9.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 34.0;cerebellum: 19.1;cerebral cortex: 23.9;hippocampal formation: 17.9;olfactory bulb: 8.9" "HPA014551, HPA019445, HPA076421" Enhanced Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA014551: AB_2669038, HPA019445: AB_1852118, HPA076421: " "unprognostic (9.12e-2)" "unprognostic (4.82e-3)" "unprognostic (2.63e-1)" "unprognostic (6.70e-2)" "unprognostic (3.56e-1)" "unprognostic (3.63e-2)" "unprognostic (1.73e-1)" "unprognostic (9.36e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-1)" "unprognostic (1.46e-2)" "unprognostic (2.77e-2)" "unprognostic (1.42e-3)" "unprognostic (1.17e-1)" "unprognostic (8.89e-2)" "unprognostic (1.36e-1)" "unprognostic (9.70e-2)" 0.2 0.9 6.8 0.4 9.2 0.0 0.2 9.5 17.9 0.7 2.7 0.5 0.3 0.4 0.2 0.1 0.6 0.2 0.0 11.2 5.3 0.1 0.1 0.0 0.0 4.8 4.4 0.1 0.2 0.0 0.7 0.3 4.0 0.5 0.3 0.3 0.1 0.1 0.2 0.1 0.8 0.2 4.0 0.0 0.5 1.5 4.9 0.2 0.1 0.6 0.0 0.2 0.4 8.3 0.0 2.1 0.4 0.1 0.0 0.1 0.1 1.0 0.2 2.1 2.4 0.0 0.0 0.0 0.0 1.4 2.4 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 6.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 10.1 0.0 6.0 0.0 0.4 12.9 2.4 0.2 12.9 1.7 9.2 0.0 0.0 1.6 0.2 2.0 1.2 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.8 9.2 9.5 17.9 11.2 5.3 4.8 4.4 4.0 4.0 4.9 8.3 0.2 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 11.2 0.2 2.8 0.1 0.0 0.0 533.5 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 261.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 7.5 0.0 0.0 0.0 19.1 116.6 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNIP1 KCHIP1 ENSG00000182132 "Potassium voltage-gated channel interacting protein 1" Q9NZI2 5 170353487-170736632 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7;choroid plexus: 15.1;epididymis: 21.6" "Cell type enhanced" "Detected in some" "Astrocytes: 57.8;Horizontal cells: 50.5;Inhibitory neurons: 221.4;Microglial cells: 167.7;Oligodendrocyte precursor cells: 196.1" "Cancer enriched" "Detected in some" 18 "glioma: 22.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 24 "RPTEC TERT1: 58.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022864, HPA066717" Uncertain Approved Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA022864: AB_1858712, HPA066717: " "unprognostic (7.75e-5)" "unprognostic (2.66e-2)" "unprognostic (6.78e-2)" "unprognostic (3.22e-4)" "unprognostic (4.51e-2)" "unprognostic (3.49e-1)" "unprognostic (1.25e-2)" "unprognostic (2.69e-1)" "unprognostic (5.46e-2)" "unprognostic (6.62e-3)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (2.55e-1)" "unprognostic (2.58e-2)" "unprognostic (1.63e-1)" "unprognostic (2.39e-1)" "unprognostic (6.05e-2)" 0.5 4.2 23.5 0.5 26.5 0.0 1.0 19.4 28.3 2.7 15.1 0.7 0.2 1.6 21.6 0.3 1.7 1.8 0.4 21.8 32.6 3.8 0.1 1.0 0.5 24.3 26.6 0.3 1.4 1.3 1.0 1.2 24.7 1.5 0.5 5.8 0.4 5.6 0.1 0.4 0.3 1.1 28.7 1.5 0.4 2.7 32.7 0.1 0.7 0.2 0.4 0.5 0.6 19.6 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 58.7 0.0 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.5 26.5 19.4 28.3 21.8 32.6 24.3 26.6 24.7 28.7 32.7 19.6 0.0 0.0 0.0 57.8 0.0 0.4 0.1 0.0 0.0 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 2.0 1.2 0.0 0.0 18.6 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 50.5 221.4 0.0 0.0 0.0 0.6 0.7 5.0 0.1 0.0 167.7 0.0 0.2 0.0 196.1 2.8 0.0 0.0 11.7 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 KCNIP2 KCHIP2 ENSG00000120049 "Potassium voltage-gated channel interacting protein 2" Q9NS61 10 101825974-101843920 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 227.4;brain: 139.6;heart muscle: 307.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 54.3;Cardiomyocytes: 135.7;Cone photoreceptor cells: 25.0;Excitatory neurons: 23.3;Horizontal cells: 48.8;Inhibitory neurons: 41.9" "Cancer enhanced" "Detected in many" "glioma: 3.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 21.3;HMC-1: 12.7" "Group enriched" "Detected in all" 4 "amygdala: 96.8;basal ganglia: 234.9;cerebral cortex: 106.9;hippocampal formation: 142.6;olfactory bulb: 144.0" "Low region specificity" "Detected in all" HPA066717 Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA066717: " "unprognostic (5.92e-2)" "unprognostic (2.16e-1)" "unprognostic (3.48e-3)" "unprognostic (5.77e-4)" "unprognostic (1.34e-1)" "unprognostic (1.31e-3)" "unprognostic (8.80e-2)" "unprognostic (9.11e-3)" "unprognostic (1.14e-1)" "unprognostic (5.34e-2)" "unprognostic (3.18e-2)" "unprognostic (7.20e-2)" "unprognostic (1.49e-9)" "unprognostic (9.85e-2)" "unprognostic (1.81e-1)" "unprognostic (3.27e-1)" "unprognostic (8.37e-4)" 227.4 6.8 74.5 3.5 139.6 0.9 67.1 48.8 84.5 7.4 40.5 5.0 1.8 4.1 4.1 2.5 4.9 3.1 307.5 98.8 50.6 2.8 2.3 2.5 8.1 47.5 51.6 11.5 2.4 1.7 19.7 2.9 48.1 5.2 4.7 52.6 9.9 3.5 8.0 5.9 5.3 2.6 50.3 5.7 2.7 8.5 57.1 2.3 3.5 5.4 8.3 4.8 4.4 60.8 1.7 2.6 2.5 3.2 1.0 1.1 0.6 1.2 1.0 0.6 0.9 3.6 3.4 1.6 0.9 0.8 0.7 1.7 0.9 0.4 0.6 2.4 2.0 21.3 3.0 1.9 0.9 1.4 12.7 2.6 1.7 1.0 1.4 3.7 1.0 4.7 6.3 1.8 1.0 1.2 0.8 4.0 0.8 0.7 0.6 1.0 0.2 1.4 1.0 1.1 7.4 1.2 0.8 0.6 2.4 1.5 2.2 0.9 2.3 1.3 2.0 0.6 1.2 1.7 1.9 1.7 1.4 5.3 0.2 0.0 0.0 0.7 0.0 0.5 0.1 0.9 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 74.5 139.6 48.8 84.5 98.8 50.6 47.5 51.6 48.1 50.3 57.1 60.8 0.4 0.0 0.0 8.5 2.3 0.4 0.1 0.3 0.0 54.3 0.3 0.5 135.7 0.0 0.1 1.8 25.0 0.2 0.0 0.8 0.0 0.2 6.6 0.0 0.2 1.6 0.0 0.0 23.3 0.0 0.2 5.8 0.0 0.0 0.0 0.8 0.4 0.1 2.2 48.8 41.9 0.4 0.0 0.6 0.8 5.2 1.8 0.3 0.0 1.0 0.5 8.3 0.0 5.5 3.7 0.3 0.2 0.7 0.3 0.1 0.5 0.1 0.2 4.7 0.0 0.1 1.3 2.5 5.5 0.5 0.0 0.3 0.1 0.5 0.3 0.1 KCNIP3 "CSEN, DREAM, KCHIP3" ENSG00000115041 "Potassium voltage-gated channel interacting protein 3" Q9Y2W7 2 95297327-95386077 "Predicted intracellular proteins, Transporters" "Apoptosis, Ion transport, Potassium transport, Transcription, Transcription regulation, Transport" "Ion channel, Potassium channel, Repressor, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 39.0;Leydig cells: 25.4;Oligodendrocyte precursor cells: 54.8;Peritubular cells: 42.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 13.8;BJ hTERT+: 18.0;hTERT-RPE1: 23.2;RPTEC TERT1: 35.2;U-138 MG: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066717, HPA069797" Enhanced Approved Vesicles "Intracellular and membrane" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA066717: , HPA069797: AB_2686199" "unprognostic (1.05e-2)" "unprognostic (5.76e-2)" "unprognostic (3.33e-3)" "prognostic unfavorable (1.58e-5)" "unprognostic (2.67e-1)" "unprognostic (6.73e-2)" "unprognostic (2.23e-1)" "unprognostic (2.96e-1)" "unprognostic (2.73e-1)" "unprognostic (7.42e-2)" "unprognostic (2.32e-1)" "unprognostic (4.09e-1)" "unprognostic (1.44e-3)" "unprognostic (8.90e-2)" "unprognostic (6.51e-2)" "unprognostic (7.33e-2)" "unprognostic (1.04e-1)" 6.7 1.5 21.8 0.8 20.0 0.0 5.4 15.2 31.2 10.7 12.2 9.8 1.2 10.6 3.6 2.4 10.1 1.5 6.0 22.1 16.8 8.4 2.0 2.4 0.4 15.4 17.2 10.1 2.4 27.0 6.4 5.3 15.2 9.3 0.9 0.5 5.6 14.7 1.5 6.0 3.7 5.1 15.3 2.6 5.5 12.2 18.0 24.4 19.7 1.8 0.5 9.0 10.6 19.3 13.8 0.0 0.8 6.1 5.3 4.2 0.0 6.3 18.0 10.1 9.3 0.0 0.0 0.0 0.6 8.3 5.5 0.2 4.0 1.1 4.3 0.0 1.4 0.0 1.8 0.0 2.2 0.0 0.0 2.9 3.6 2.2 10.0 23.2 0.0 1.0 0.0 0.0 0.8 8.0 0.1 0.0 0.1 0.0 3.7 0.0 0.0 0.0 35.2 0.0 0.7 0.2 0.3 0.3 6.8 0.0 0.3 0.1 0.3 16.3 3.8 0.0 4.9 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 20.0 15.2 31.2 22.1 16.8 15.4 17.2 15.2 15.3 18.0 19.3 0.4 0.0 1.1 13.4 0.5 0.4 0.8 0.0 1.2 8.1 1.0 1.0 1.6 0.0 0.0 1.8 0.0 0.0 0.0 0.2 7.9 0.2 0.6 0.3 3.7 1.0 4.2 0.0 39.0 0.0 0.1 3.5 0.0 0.3 0.0 7.5 0.0 0.5 0.1 0.0 5.1 0.1 0.0 0.0 0.4 1.3 25.4 0.1 7.2 1.9 0.6 0.5 0.0 54.8 3.0 0.2 0.0 42.9 0.0 0.5 1.0 1.5 0.0 0.0 0.0 8.3 3.7 0.1 0.9 0.2 0.9 0.0 0.0 1.5 0.3 0.1 KCNIP4 "CALP, KCHIP4, MGC44947" ENSG00000185774 "Potassium voltage-gated channel interacting protein 4" Q6PIL6 4 20728606-21948772 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.5;retina: 18.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9816.7;Inhibitory neurons: 1982.4;Oligodendrocyte precursor cells: 5175.8" "Cancer enhanced" "Detected in some" "glioma: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "RPTEC TERT1: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022862, HPA066717" Supported Approved Vesicles NA NA "Cluster 58: Brain - Synaptic function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA022862: AB_1852654, HPA066717: " "unprognostic (8.08e-2)" "unprognostic (1.05e-1)" "unprognostic (7.36e-2)" "unprognostic (4.14e-2)" "unprognostic (9.26e-2)" "unprognostic (1.49e-1)" "unprognostic (2.53e-1)" "unprognostic (2.99e-2)" "unprognostic (1.18e-1)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (2.13e-1)" "unprognostic (3.11e-1)" "unprognostic (1.03e-2)" "unprognostic (2.69e-1)" "unprognostic (4.59e-2)" "unprognostic (2.10e-2)" 0.6 2.2 11.9 1.3 16.4 0.0 0.6 13.8 24.5 11.0 0.0 6.9 1.2 6.2 0.6 4.0 2.5 1.1 0.5 17.8 12.8 8.2 0.2 0.5 0.0 7.0 7.9 1.3 0.5 0.0 4.2 1.0 13.7 0.5 4.1 18.1 0.5 0.3 0.3 0.5 3.8 6.0 4.3 0.3 0.8 0.4 9.0 0.0 6.4 0.0 0.0 1.0 1.5 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.4 0.4 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 16.4 13.8 24.5 17.8 12.8 7.0 7.9 13.7 4.3 9.0 10.6 0.0 0.0 0.0 148.2 0.1 0.0 0.0 0.0 0.0 33.0 0.1 0.0 0.5 0.0 0.0 14.7 0.0 0.1 0.0 0.3 62.6 0.1 9.8 0.2 2.1 1.6 0.0 0.0 9816.7 0.0 0.0 3.1 0.0 0.2 0.0 12.3 1.1 0.2 0.2 0.0 1982.4 0.6 0.0 0.0 0.0 4.2 0.0 0.5 3.6 119.9 0.6 45.9 0.0 5175.8 91.4 0.0 7.8 0.0 0.0 0.0 0.4 15.2 0.0 12.6 0.0 0.2 0.4 0.1 0.7 0.1 0.1 0.1 0.1 14.5 0.7 0.1 KCNJ16 "BIR9, Kir5.1" ENSG00000153822 "Potassium inwardly rectifying channel subfamily J member 16" Q9NPI9 17 70053429-70135608 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 196.1;parathyroid gland: 269.2;thyroid gland: 139.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 54.3;Collecting duct cells: 244.6;Distal tubular cells: 41.1;Oligodendrocyte precursor cells: 54.8;Proximal tubular cells: 95.2" "Group enriched" "Detected in many" 10 "renal cancer: 37.2;thyroid cancer: 80.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.6" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.6" "Cell line enriched" "Detected in some" 22 "RPTEC TERT1: 279.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059563 Approved Uncertain Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA059563: AB_2684065" "unprognostic (2.81e-3)" "unprognostic (2.10e-1)" "unprognostic (6.06e-2)" "unprognostic (1.20e-3)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (4.38e-4)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.34e-1)" "prognostic favorable (9.61e-7)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "prognostic favorable (6.58e-4)" "unprognostic (3.88e-1)" 0.3 0.4 10.0 0.4 14.0 0.6 3.8 22.7 11.6 0.1 2.3 0.6 0.7 0.5 15.9 0.3 5.1 18.8 0.6 6.8 39.5 196.1 1.3 0.9 0.8 39.7 37.6 0.2 44.2 269.2 1.0 0.9 25.7 0.2 0.2 1.2 11.8 21.7 0.3 0.8 2.5 0.0 29.9 1.5 23.4 1.7 27.3 0.2 139.4 0.0 0.1 0.0 0.0 20.8 0.1 0.4 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.6 0.0 1.2 0.5 0.0 0.2 0.0 0.0 0.0 0.2 1.2 0.8 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.3 0.6 0.1 0.0 12.7 0.0 0.0 279.8 0.2 0.3 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.4 0.0 0.3 0.1 0.1 0.0 0.2 0.8 0.2 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.3 0.3 0.3 0.1 0.0 0.3 0.2 0.2 1.6 0.3 0.0 0.1 0.3 0.1 10.0 14.0 22.7 11.6 6.8 39.5 39.7 37.6 25.7 29.9 27.3 20.8 0.1 0.0 0.0 12.1 0.0 0.0 0.0 2.7 0.0 0.0 2.3 1.1 0.4 54.3 2.6 244.6 0.0 0.0 0.0 0.0 41.1 12.4 0.0 2.8 0.1 0.0 0.0 0.0 1.0 1.4 0.0 0.3 3.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 54.8 0.1 6.0 0.0 0.0 0.0 0.0 1.0 95.2 9.8 0.0 0.0 0.2 0.3 0.2 0.6 0.0 0.0 0.0 0.6 0.2 0.0 0.0 KCNK1 "DPK, K2p1.1, TWIK-1" ENSG00000135750 "Potassium two pore domain channel subfamily K member 1" O00180 1 233614106-233672514 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 157.8;Horizontal cells: 200.2;Prostatic glandular cells: 222.9;Urothelial cells: 371.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 69 "plasmacytoid DC: 6.9" "Lineage enriched" "Detected in single" 69 "dendritic cells: 6.9" "Cell line enhanced" "Detected in many" "HeLa: 64.7;SCLC-21H: 62.5;U-266/70: 137.3;U-266/84: 134.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 117.0" "HPA016049, CAB022588" Approved Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 45: Intestine - Brush border" "Cluster 29: U-266 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "CAB022588: , HPA016049: AB_1855571" "unprognostic (7.06e-3)" "unprognostic (1.76e-1)" "unprognostic (4.64e-2)" "unprognostic (7.46e-2)" "unprognostic (9.15e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.84e-4)" "unprognostic (4.32e-2)" "unprognostic (6.15e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (7.29e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" 3.9 4.1 17.7 2.9 19.8 0.3 5.7 58.0 28.4 7.8 50.4 15.7 16.9 6.1 30.9 20.9 10.9 12.1 41.0 24.3 13.7 9.2 12.1 4.4 1.0 23.5 17.8 7.3 5.5 16.2 22.2 6.8 24.1 6.4 13.9 18.5 15.1 11.3 0.4 13.3 12.6 3.8 15.4 0.9 38.1 0.9 16.3 0.5 7.2 0.9 4.4 11.5 14.4 21.3 33.2 18.3 0.1 0.0 0.0 0.0 50.2 8.8 0.0 0.0 0.0 0.0 52.9 0.0 20.7 6.8 7.3 47.1 8.9 15.2 0.0 0.1 15.8 0.0 64.7 0.0 0.5 0.0 1.8 3.9 17.0 0.0 12.4 1.1 0.2 17.7 7.9 15.0 0.0 12.6 12.2 0.1 10.9 38.5 41.0 0.0 2.7 3.7 16.0 28.4 62.5 11.8 33.5 14.3 0.0 1.0 4.1 0.1 0.0 0.1 25.8 0.0 1.0 137.3 134.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 17.7 19.8 58.0 28.4 24.3 13.7 23.5 17.8 24.1 15.4 16.3 21.3 0.4 9.6 22.9 5.9 0.6 63.3 136.7 32.6 3.4 2.9 23.0 6.0 54.7 12.8 44.6 18.4 4.2 0.5 3.0 91.0 1.9 29.2 1.1 52.7 26.4 3.5 29.3 0.0 157.8 48.3 14.0 31.2 50.4 89.3 0.0 15.0 0.0 8.9 0.6 200.2 61.0 56.3 24.4 0.3 4.4 0.2 1.5 1.0 10.6 12.2 0.0 72.6 0.0 36.2 73.2 96.3 82.4 0.0 0.2 222.9 10.6 8.8 42.9 5.1 0.0 2.3 6.9 0.6 3.2 19.1 47.6 0.8 1.4 0.5 31.2 371.6 KCNQ5 Kv7.5 ENSG00000185760 "Potassium voltage-gated channel subfamily Q member 5" Q9NR82 6 72621792-73198853 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 28.3;skeletal muscle: 21.1;tongue: 12.2" "Group enriched" "Detected in some" 30 "Excitatory neurons: 2136.7;Inhibitory neurons: 862.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 28.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 34.9;HEL: 23.2;HL-60: 31.5;U-251 MG: 23.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016655 Approved Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA016655: AB_1855557" "unprognostic (4.91e-2)" "unprognostic (1.42e-1)" "unprognostic (4.96e-2)" "unprognostic (3.78e-2)" "unprognostic (2.69e-1)" "unprognostic (2.18e-2)" "unprognostic (3.57e-2)" "unprognostic (1.43e-1)" "unprognostic (6.09e-2)" "unprognostic (8.55e-2)" "unprognostic (7.96e-2)" "unprognostic (1.05e-1)" "unprognostic (6.77e-2)" "unprognostic (1.08e-2)" "unprognostic (2.62e-1)" "unprognostic (8.16e-2)" "unprognostic (1.39e-3)" 0.1 1.6 1.2 1.3 7.5 5.1 0.4 0.0 28.3 0.4 0.0 0.4 0.2 0.1 0.0 0.9 0.3 0.3 0.2 4.3 0.0 0.1 0.2 0.3 2.2 17.4 1.0 0.1 0.1 0.0 0.2 0.4 19.4 1.3 0.3 0.2 1.2 0.9 21.1 0.1 0.7 0.3 0.0 1.1 0.3 1.2 0.0 1.7 4.7 12.2 2.0 0.9 0.6 4.6 4.4 1.1 0.0 0.2 0.0 1.5 0.0 34.9 5.2 5.1 4.3 0.0 0.0 21.2 0.0 11.9 0.4 0.7 0.1 2.1 6.1 0.3 7.2 23.2 0.1 0.0 0.9 31.5 0.0 0.3 0.8 14.5 14.9 3.3 0.0 0.0 1.4 14.2 10.2 0.1 0.0 13.5 1.3 0.0 7.1 0.0 1.1 14.4 1.9 0.0 5.8 2.7 0.0 0.1 13.7 0.2 4.3 2.3 0.0 21.0 9.2 0.1 23.4 14.8 0.4 9.3 0.2 14.9 1.2 0.3 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.4 0.1 0.3 0.3 0.3 0.0 0.6 0.0 0.0 0.0 0.0 1.2 7.5 0.0 28.3 4.3 0.0 17.4 1.0 19.4 0.0 0.0 4.6 0.0 0.0 0.0 38.8 7.6 0.3 3.6 0.7 5.2 0.3 0.4 0.5 3.6 0.0 0.1 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 5.5 2136.7 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 862.4 0.0 0.0 0.0 1.5 1.6 0.0 0.2 1.8 49.6 0.0 0.1 1.0 30.2 26.7 0.0 0.0 0.0 7.6 5.7 0.0 0.0 0.0 0.2 0.0 6.0 0.8 0.5 0.5 0.8 0.3 0.3 2.8 0.0 0.0 0.7 KCNRG ENSG00000198553 "Potassium channel regulator" Q8N5I3 13 50015254-50020922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "fallopian tube: 35.7" "Cell type enhanced" "Detected in some" "Early spermatids: 19.4;Endometrial ciliated cells: 46.0;Late spermatids: 12.6;Respiratory ciliated cells: 88.6" "Cancer enhanced" "Detected in single" "endometrial cancer: 1.6" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "JURKAT: 3.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001027 Uncertain Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA001027: " "unprognostic (1.85e-3)" "unprognostic (1.66e-2)" "unprognostic (1.08e-2)" "prognostic favorable (2.61e-5)" "unprognostic (3.15e-1)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (5.39e-3)" "unprognostic (1.26e-1)" "unprognostic (1.09e-1)" "unprognostic (1.71e-1)" "unprognostic (5.91e-1)" "unprognostic (1.65e-2)" "unprognostic (4.98e-2)" "unprognostic (4.69e-2)" "unprognostic (1.52e-1)" "unprognostic (9.16e-2)" 0.6 0.3 0.5 0.6 2.3 1.9 0.8 3.2 1.6 1.4 0.1 0.6 0.5 1.3 0.5 0.8 35.7 0.4 0.6 0.5 1.2 0.8 0.4 3.1 0.6 2.1 0.9 0.5 0.4 1.1 0.5 0.2 1.3 0.6 0.8 0.8 0.5 0.4 0.6 0.9 0.6 0.5 0.6 0.6 0.5 2.0 1.5 0.6 0.5 0.5 0.6 0.7 0.5 3.5 0.4 0.3 1.1 0.4 0.4 0.5 0.2 0.0 0.9 0.8 0.0 1.3 0.4 0.8 0.2 1.1 0.5 0.5 0.8 0.3 0.6 0.6 0.5 1.7 0.5 0.7 1.0 1.5 0.4 0.6 0.8 0.5 1.4 0.7 1.6 3.1 0.7 0.1 1.0 0.5 1.6 1.5 0.9 1.0 0.6 1.0 0.0 0.0 0.7 1.0 1.0 2.2 0.3 0.7 0.8 0.6 0.6 0.4 0.5 0.7 0.3 0.4 0.3 0.1 0.2 0.9 0.2 0.5 0.2 1.0 0.3 0.2 0.1 0.3 0.2 0.4 0.1 0.3 0.3 0.6 0.2 0.2 1.2 0.4 0.2 0.3 0.4 0.1 0.5 2.3 3.2 1.6 0.5 1.2 2.1 0.9 1.3 0.6 1.5 3.5 1.1 0.0 2.7 0.7 0.9 0.1 0.9 3.8 0.0 1.0 0.6 0.9 0.5 0.0 6.2 0.0 2.1 0.8 0.5 0.8 0.0 0.5 19.4 46.0 1.0 0.8 4.2 0.0 0.7 1.4 0.5 0.8 0.0 1.0 0.0 0.5 0.0 0.3 0.5 3.3 0.7 0.9 0.0 0.0 0.3 12.6 0.6 1.3 0.0 0.0 1.3 0.7 0.0 1.0 0.5 0.6 0.3 0.7 0.0 0.9 0.8 2.1 88.6 1.2 0.0 1.4 1.5 11.4 1.5 0.0 0.1 0.7 0.5 0.5 0.7 1.3 KCNT2 "KCa4.2, SLICK, SLO2.1" ENSG00000162687 "Potassium sodium-activated channel subfamily T member 2" Q6UVM3 1 196225779-196609225 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 220.2;Inhibitory neurons: 240.5;Oligodendrocyte precursor cells: 310.7" "Cancer enhanced" "Detected in some" "renal cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 3.2;hTERT-RPE1: 9.0;SCLC-21H: 7.5;SH-SY5Y: 5.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051218 Uncertain Approved Vesicles NA NA "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA051218: AB_2681392" "unprognostic (5.06e-2)" "unprognostic (2.94e-2)" "unprognostic (8.01e-2)" "unprognostic (5.10e-6)" "unprognostic (1.22e-3)" "unprognostic (1.30e-2)" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (5.90e-2)" "unprognostic (2.18e-1)" "unprognostic (9.56e-3)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.67e-5)" "unprognostic (3.30e-4)" "unprognostic (2.95e-2)" "unprognostic (4.75e-1)" "unprognostic (1.72e-3)" 1.0 0.6 0.9 0.1 2.0 0.0 0.4 0.0 2.0 0.4 0.3 0.5 0.2 0.3 0.4 1.0 0.5 1.4 1.8 2.5 3.3 0.3 2.8 1.8 0.1 0.0 0.2 3.8 0.1 0.0 0.9 0.2 0.0 1.0 0.5 0.1 0.5 0.6 0.1 0.3 0.4 0.5 0.6 0.2 0.5 1.1 1.0 0.1 1.1 0.8 0.1 0.8 0.4 0.5 0.0 0.1 1.8 0.0 0.2 0.2 0.0 0.0 1.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.9 0.0 3.2 0.0 0.0 1.2 0.0 0.4 0.1 9.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 2.4 0.0 0.1 0.0 0.1 0.0 0.0 0.5 7.5 5.6 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.0 0.0 2.0 2.5 3.3 0.0 0.2 0.0 0.6 1.0 0.5 0.8 41.7 1.1 6.8 0.0 0.4 0.2 0.0 0.6 0.0 0.0 0.1 1.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.2 0.8 0.0 0.0 220.2 0.0 0.0 9.3 0.0 0.0 0.0 6.1 2.5 6.2 0.0 0.0 240.5 0.0 0.0 0.0 0.7 3.3 6.5 0.0 1.8 58.1 0.0 0.0 0.0 310.7 6.1 0.0 0.0 4.9 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.4 4.0 0.6 0.2 0.0 0.0 0.0 0.0 3.9 0.0 0.2 KCTD8 ENSG00000183783 "Potassium channel tetramerization domain containing 8" Q6ZWB6 4 44173903-44448809 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 26.0;retina: 6.8" "Group enriched" "Detected in some" 4 "Astrocytes: 169.4;Excitatory neurons: 223.7;Inhibitory neurons: 445.3;Oligodendrocyte precursor cells: 322.7;Oligodendrocytes: 610.8" "Cancer enhanced" "Detected in some" "glioma: 0.9;thyroid cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.2;NTERA-2: 1.5;SCLC-21H: 5.7;U-2 OS: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA031562 Enhanced Approved Vesicles NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA031562: AB_10602609" "unprognostic (1.49e-2)" "unprognostic (7.70e-3)" "unprognostic (1.53e-1)" "unprognostic (4.15e-1)" "unprognostic (1.77e-2)" "unprognostic (1.48e-1)" "unprognostic (7.85e-2)" "unprognostic (2.62e-3)" "unprognostic (1.33e-1)" "unprognostic (4.58e-3)" "unprognostic (2.57e-3)" "unprognostic (8.72e-2)" "unprognostic (3.55e-2)" "unprognostic (2.44e-1)" 1.5 0.2 5.4 0.0 9.6 0.0 0.0 26.0 7.0 1.0 3.6 0.9 0.0 1.4 0.2 0.1 0.2 0.3 0.2 6.4 11.5 0.8 0.0 0.1 0.0 9.2 12.7 1.5 0.6 1.0 0.0 0.0 10.2 0.4 0.1 6.8 0.4 0.9 1.5 0.1 0.1 0.5 14.6 0.0 1.5 1.3 8.2 0.0 3.0 1.1 0.0 0.1 0.3 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.9 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 9.6 26.0 7.0 6.4 11.5 9.2 12.7 10.2 14.6 8.2 16.3 0.1 0.0 0.0 169.4 0.0 0.0 0.6 0.0 1.8 2.6 1.3 0.3 0.3 4.3 0.0 3.7 4.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 3.5 1.0 0.0 0.0 223.7 0.0 0.0 1.0 0.0 0.1 0.0 2.0 0.4 0.0 0.1 0.0 445.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 71.2 0.0 4.4 0.0 322.7 610.8 0.2 0.0 0.0 0.0 1.2 0.0 1.9 0.0 17.1 0.0 1.7 0.2 0.1 1.6 1.0 0.0 0.1 0.0 10.0 0.0 0.1 KIAA0319 NMIG ENSG00000137261 KIAA0319 Q5VV43 6 24544104-24646191 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.3;pituitary gland: 4.1" "Group enriched" "Detected in some" 8 "Astrocytes: 119.5;Early spermatids: 65.6;Excitatory neurons: 129.2;Inhibitory neurons: 72.7;Late spermatids: 96.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Lineage enhanced" "Detected in single" "granulocytes: 1.6" "Cell line enhanced" "Detected in some" "A-431: 2.0;A549: 2.0;GAMG: 2.1;HDLM-2: 2.4;HeLa: 1.9;SCLC-21H: 3.8;U-266/84: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015607, HPA076313" Enhanced Supported Approved Vesicles "Secreted in brain" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA015607: AB_1852299, HPA076313: AB_2732308" "unprognostic (1.64e-1)" "unprognostic (2.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (1.77e-1)" "unprognostic (1.72e-2)" "unprognostic (4.65e-2)" "unprognostic (9.70e-2)" "unprognostic (2.21e-5)" "unprognostic (7.88e-4)" "unprognostic (9.53e-4)" "unprognostic (1.44e-6)" "unprognostic (1.20e-1)" "unprognostic (6.97e-2)" "unprognostic (3.13e-1)" "unprognostic (3.41e-2)" 0.0 0.4 10.0 0.2 10.3 0.0 0.1 4.3 10.4 0.1 0.6 0.4 0.0 0.0 0.0 0.0 1.6 0.2 0.0 9.2 5.8 0.0 0.0 0.6 0.0 7.2 7.4 0.0 1.4 0.1 4.1 0.0 7.6 0.4 0.4 1.2 0.2 0.0 0.0 0.7 0.2 0.1 2.7 0.2 0.8 1.1 12.3 0.0 0.0 0.0 0.1 0.0 0.0 4.8 2.0 2.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.6 0.9 0.0 2.1 0.8 0.3 0.0 0.0 2.4 1.0 0.0 1.9 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.3 0.0 0.1 3.8 0.2 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.4 0.3 3.2 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 10.0 10.3 4.3 10.4 9.2 5.8 7.2 7.4 7.6 2.7 12.3 4.8 0.1 3.2 0.5 119.5 0.6 0.0 0.0 0.5 0.0 3.6 0.1 0.1 1.4 0.0 1.5 0.0 0.0 0.0 0.0 1.4 0.0 0.4 65.6 2.6 0.1 0.0 10.2 0.0 129.2 0.0 0.0 0.3 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 72.7 0.8 0.0 0.0 0.0 96.8 0.6 0.2 0.0 5.6 0.6 0.3 0.0 5.0 3.1 0.3 0.1 0.7 0.0 0.2 0.0 0.1 10.9 0.9 0.0 0.1 0.0 1.2 1.5 0.0 0.0 0.7 0.1 0.1 0.3 0.3 KIF5C ENSG00000168280 "Kinesin family member 5C" O60282 2 148875227-149026759 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Transport "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 65.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 252.2;Early spermatids: 568.4;Excitatory neurons: 267.2;Inhibitory neurons: 249.1;Late spermatids: 702.5;Oligodendrocytes: 270.7" "Cancer enhanced" "Detected in many" "glioma: 11.7;prostate cancer: 19.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 117.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035210, HPA062272" Enhanced Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA035210: AB_10671931, HPA062272: AB_2732678" "unprognostic (1.95e-1)" "unprognostic (2.39e-1)" "unprognostic (2.54e-1)" "unprognostic (4.70e-4)" "unprognostic (1.89e-1)" "unprognostic (3.79e-2)" "unprognostic (1.24e-1)" "unprognostic (3.90e-2)" "unprognostic (2.86e-1)" "unprognostic (1.41e-2)" "unprognostic (6.61e-3)" "unprognostic (1.56e-1)" "unprognostic (6.55e-6)" "unprognostic (8.34e-3)" "unprognostic (3.69e-1)" "unprognostic (3.63e-2)" "unprognostic (4.46e-2)" 0.5 5.1 41.3 0.6 17.6 0.0 0.5 13.9 65.2 1.4 0.0 1.1 0.3 0.5 3.7 0.1 0.9 0.1 0.6 28.9 13.7 0.2 0.0 0.2 0.3 15.4 9.0 1.6 2.3 0.3 5.5 0.0 24.6 10.4 0.6 7.8 0.2 2.8 0.3 0.3 0.8 0.4 16.3 0.2 0.6 12.1 49.8 0.1 1.3 0.9 0.2 0.6 1.4 32.0 0.0 0.0 17.8 3.6 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.2 0.0 0.7 0.0 0.2 5.4 0.0 14.1 0.0 1.3 13.7 3.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.7 0.0 0.7 0.0 0.1 0.0 0.8 0.0 0.0 22.4 0.0 9.2 0.0 0.1 0.1 0.0 3.6 117.1 27.1 0.2 0.5 0.2 2.8 0.0 0.0 0.0 0.0 3.3 0.0 3.7 3.0 0.4 0.0 8.8 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.3 17.6 13.9 65.2 28.9 13.7 15.4 9.0 24.6 16.3 49.8 32.0 1.8 0.0 0.0 33.6 2.4 1.3 6.1 0.1 2.2 252.2 8.0 3.7 14.9 4.3 0.0 18.4 108.4 0.0 0.8 1.1 0.0 0.3 568.4 0.9 1.6 6.1 129.7 0.0 267.2 0.0 0.1 4.9 2.0 0.2 0.0 1.1 0.7 0.0 0.2 99.3 249.1 2.7 4.1 0.3 1.9 702.5 8.1 0.8 5.4 10.3 0.8 8.5 2.1 125.2 270.7 0.9 3.4 12.8 1.7 35.8 0.1 0.1 0.0 15.1 6.6 1.6 9.1 15.8 10.7 0.2 0.4 0.0 11.9 0.3 4.9 2.3 KISS1 ENSG00000170498 "KiSS-1 metastasis suppressor" Q15726 1 204190341-204196491 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "placenta: 233.1" "Cell type enriched" "Detected in many" 26 "Syncytiotrophoblasts: 1336.6" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.2" "Region enriched" "Detected in some" 6 "hypothalamus: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "BJ: 145.5;U-2 OS: 59.4" "Not detected" "Not detected" "CAB017775, HPA035542" Enhanced Approved Vesicles "Secreted in female reproductive system" NA NA 860000 "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "CAB017775: , HPA035542: AB_2674677" "unprognostic (9.64e-2)" "unprognostic (1.78e-2)" "unprognostic (1.86e-2)" "unprognostic (1.18e-2)" "unprognostic (3.89e-1)" "unprognostic (6.87e-2)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (1.63e-1)" "unprognostic (8.98e-12)" "unprognostic (2.25e-1)" "unprognostic (2.91e-2)" "unprognostic (1.76e-1)" "prognostic favorable (6.29e-6)" 0.0 0.0 0.4 0.0 0.8 0.0 0.1 0.6 0.6 0.3 0.8 0.2 0.9 0.2 0.0 0.1 0.1 0.0 0.1 0.4 10.7 2.4 4.3 1.3 0.0 1.8 0.3 0.0 1.0 0.0 3.1 233.1 0.4 0.6 0.0 0.0 0.1 0.0 0.0 0.1 1.3 0.2 0.2 2.0 3.2 5.2 1.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 2.4 145.5 1.8 2.5 0.7 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.9 0.2 0.0 0.2 0.1 0.0 0.0 0.9 0.2 0.1 0.0 0.7 0.0 0.8 0.2 0.3 0.0 0.1 59.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.6 0.6 0.4 10.7 1.8 0.3 0.4 0.2 1.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 4.0 7.5 0.0 1.0 1.2 0.6 0.0 1.5 2.2 0.0 0.0 9.3 0.0 1.5 0.0 11.3 40.2 0.2 0.0 1.4 0.0 0.0 0.1 4.9 6.9 1.9 4.1 0.5 0.0 0.4 0.7 2.8 15.1 0.0 0.0 0.6 0.0 0.0 0.0 5.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.5 0.0 0.1 50.1 17.0 1.4 0.4 0.0 0.0 0.0 7.1 0.6 1.1 0.0 0.0 1336.6 0.1 0.1 2.1 14.3 KITLG "DFNA69, FPH2, Kitl, KL-1, MGF, SCF, SF, SLF" ENSG00000049130 "KIT ligand" P21583 12 88492793-88580851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Cell adhesion" "Growth factor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 83.6;Collecting duct cells: 69.9;Excitatory neurons: 46.5;Inhibitory neurons: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 299.8;SK-BR-3: 118.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070395 Approved Approved Vesicles "Intracellular and membrane" NA NA 260000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA070395: AB_2686264" "unprognostic (7.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.70e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.22e-3)" "unprognostic (5.61e-3)" "unprognostic (7.89e-2)" "unprognostic (5.47e-3)" "unprognostic (5.03e-2)" "prognostic favorable (5.81e-7)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (1.54e-2)" 13.2 3.9 2.3 8.2 3.5 0.3 10.6 0.2 3.1 12.9 1.2 18.7 9.6 15.1 2.8 14.3 4.0 18.5 7.0 2.9 0.3 16.0 2.3 31.6 3.3 0.0 2.5 6.0 3.7 3.7 0.2 15.0 0.0 15.1 22.6 2.3 8.8 14.8 3.1 7.1 11.6 18.8 0.3 3.5 17.4 6.3 5.2 5.1 5.9 14.4 10.4 12.3 1.3 6.2 14.3 7.1 7.1 0.9 29.0 61.5 0.0 77.6 60.1 13.5 6.4 299.8 11.0 0.0 2.2 73.3 14.9 49.5 11.5 20.1 14.2 0.1 9.5 0.0 9.5 2.6 4.4 1.9 0.0 53.5 20.6 41.6 26.8 6.3 17.9 0.0 0.0 0.3 6.8 2.5 0.2 0.0 4.8 17.7 17.9 0.0 12.6 0.0 25.0 6.5 2.3 4.8 18.5 118.9 2.2 6.5 57.2 4.3 10.0 60.7 7.4 69.0 6.8 0.0 0.0 0.0 8.4 0.2 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.5 0.2 3.1 2.9 0.3 0.0 2.5 0.0 0.3 5.2 6.2 42.5 19.2 38.3 9.4 0.5 13.5 11.2 7.5 83.6 2.7 12.2 8.1 4.4 1.5 16.5 69.9 0.0 0.1 0.0 12.0 1.9 4.4 0.4 3.1 6.8 43.1 9.5 0.0 46.5 18.2 0.1 34.5 43.3 3.4 0.0 2.1 5.0 0.4 1.2 21.9 61.4 8.5 18.3 3.2 5.7 0.9 14.0 1.9 12.4 18.7 0.0 0.3 0.0 3.0 0.6 8.7 3.0 3.8 1.4 11.2 2.3 1.4 9.8 1.2 13.1 2.2 27.2 0.2 0.5 18.5 5.3 0.0 1.0 4.4 14.7 3.2 KLK8 "HNP, neuropsin, ovasin, PRSS19, TADG14" ENSG00000129455 "Kallikrein related peptidase 8" O60259 19 50996007-51002711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 118.0;skin 1: 87.1;vagina: 47.2" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 66.0;Suprabasal keratinocytes: 180.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.9;ovarian cancer: 30.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 88.3;CAPAN-2: 112.2;HaCaT: 83.5" "Region enriched" "Detected in all" 5 "hippocampal formation: 36.1" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "CAB019393, HPA035761" Enhanced Approved Vesicles "Secreted in other tissues" NA NA 3200000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Vesicles "CAB019393: , HPA035761: AB_2674769" "unprognostic (4.27e-3)" "unprognostic (2.59e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (5.46e-2)" "prognostic unfavorable (5.72e-4)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.10e-4)" "unprognostic (4.29e-2)" "unprognostic (4.66e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (6.17e-4)" 5.7 0.0 0.1 0.0 0.0 0.0 8.4 0.8 0.7 24.7 0.2 0.0 0.0 0.9 0.4 118.0 13.2 0.1 0.2 0.0 0.0 0.4 0.1 0.1 0.0 0.7 0.2 0.1 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 17.1 0.1 0.7 87.1 0.0 0.1 0.0 0.2 0.1 1.2 0.2 1.1 0.5 0.0 9.6 0.0 47.2 0.5 88.3 0.0 0.0 0.6 0.0 0.0 12.3 0.0 0.0 0.0 0.0 1.7 112.2 0.0 2.2 0.0 0.1 83.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.7 10.3 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.7 0.0 0.0 0.7 0.2 0.4 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.3 66.0 0.0 0.4 14.8 0.0 13.0 15.6 0.1 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.7 11.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 5.0 1.8 0.1 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.3 2.8 6.2 21.1 180.1 0.0 0.2 0.0 0.2 0.1 KLRC3 NKG2-E ENSG00000205810 "Killer cell lectin like receptor C3" Q07444 12 10412315-10420595 "Predicted membrane proteins" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.9;brain: 2.1;lymphoid tissue: 4.0" "Group enriched" "Detected in some" 4 "dendritic cells: 19.2;Oligodendrocyte precursor cells: 36.2;T-cells: 15.9" "Cancer enriched" "Detected in single" 9 "glioma: 0.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "NK-cell: 63.1" "Lineage enriched" "Detected in many" 6 "NK-cells: 63.1" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.4;GAMG: 2.8;HEL: 1.3;HeLa: 7.0;HSkMC: 1.2;SuSa: 1.3;U-698: 1.9" "HPA039910, HPA062570" Approved Uncertain Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA039910: , HPA062570: AB_2684795" "unprognostic (8.92e-4)" "unprognostic (4.47e-2)" "unprognostic (2.03e-2)" "unprognostic (1.32e-1)" "unprognostic (5.07e-3)" "unprognostic (2.48e-1)" "unprognostic (3.22e-1)" "unprognostic (9.12e-2)" "unprognostic (3.52e-3)" "unprognostic (3.09e-1)" "unprognostic (1.08e-1)" "unprognostic (3.15e-1)" 0.2 0.1 1.3 0.3 1.4 1.9 0.1 0.7 2.1 0.1 0.2 0.5 0.8 0.5 0.1 0.2 0.2 0.6 0.0 1.3 1.7 0.1 0.5 0.6 1.7 1.7 1.1 0.1 0.1 0.0 0.0 0.1 1.2 0.1 0.4 0.0 0.1 0.0 0.0 0.0 1.3 0.1 1.3 4.0 0.6 0.2 1.3 0.4 0.1 0.0 0.8 0.1 0.1 2.1 0.0 0.0 0.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.6 0.0 0.0 0.0 1.3 7.0 0.1 0.0 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.1 0.0 0.0 7.0 0.0 0.0 0.1 8.7 0.6 63.1 0.0 0.0 0.0 3.6 1.3 1.4 0.7 2.1 1.3 1.7 1.7 1.1 1.2 1.3 1.3 2.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.7 0.1 0.0 0.0 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 1.9 0.0 0.0 1.0 36.2 2.3 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.1 KLRG1 "2F1, CLEC15A, MAFA, MAFA-L" ENSG00000139187 "Killer cell lectin like receptor G1" Q96E93 12 8950044-9010760 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.4" "Group enriched" "Detected in many" 4 "dendritic cells: 93.7;granulocytes: 118.9;NK-cells: 164.8;T-cells: 109.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 390.9;MAIT T-cell: 461.3" "Lineage enriched" "Detected in all" 22 "T-cells: 461.3" "Cell line enhanced" "Detected in many" "HEL: 25.1;NTERA-2: 22.1;U-937: 17.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051403, HPA076494" Approved Enhanced Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA051403: , HPA076494: AB_2686800" "unprognostic (1.54e-2)" "unprognostic (8.42e-4)" "unprognostic (1.06e-1)" "unprognostic (1.28e-1)" "unprognostic (2.94e-1)" "unprognostic (1.53e-4)" "unprognostic (3.05e-1)" "unprognostic (2.27e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-2)" "unprognostic (3.45e-3)" "unprognostic (6.88e-2)" "unprognostic (1.71e-2)" "unprognostic (2.05e-2)" "unprognostic (4.17e-2)" "unprognostic (4.96e-2)" "unprognostic (7.86e-2)" 4.1 1.7 2.4 3.8 2.6 3.0 2.5 4.3 2.9 1.3 1.4 1.5 1.0 1.2 2.1 1.0 1.0 3.3 2.0 2.1 3.2 1.4 3.0 2.2 10.4 2.5 3.4 1.0 0.5 0.4 1.1 0.6 2.3 1.1 1.9 1.3 1.6 0.7 1.7 1.0 2.2 1.6 1.7 8.8 1.6 1.1 2.6 2.5 1.0 1.8 5.0 2.4 0.8 3.8 0.2 3.1 1.6 2.3 3.0 0.7 1.4 0.5 0.3 0.4 1.1 1.1 1.1 4.9 0.1 0.4 2.1 0.2 3.3 0.5 0.4 3.6 1.9 25.1 0.4 1.6 0.8 1.1 1.6 1.4 0.4 0.5 0.0 0.4 7.6 2.5 1.4 0.4 0.2 0.7 1.0 2.0 22.1 1.0 1.7 1.2 1.0 0.0 0.5 0.4 0.4 4.4 1.1 0.5 1.6 4.3 0.3 1.7 0.8 0.7 1.0 0.6 1.4 1.4 4.1 2.6 1.8 17.3 0.2 17.5 2.6 1.5 390.9 2.9 461.3 4.2 85.1 237.7 8.2 5.0 23.5 147.7 5.7 20.9 5.4 3.9 8.7 99.7 2.4 2.6 4.3 2.9 2.1 3.2 2.5 3.4 2.3 1.7 2.6 3.8 12.7 0.0 4.3 2.9 4.7 0.4 0.4 0.0 4.0 5.0 1.0 0.9 2.8 1.5 0.1 0.0 8.4 1.0 93.7 0.1 1.9 0.7 1.6 0.8 0.6 2.9 1.2 24.6 3.8 0.2 0.5 1.3 0.5 0.5 118.9 0.9 25.7 2.0 3.4 5.0 3.6 0.1 0.0 9.1 1.4 3.1 0.6 3.7 1.8 2.8 5.4 1.8 164.8 9.5 6.2 0.3 0.1 0.0 16.9 0.2 0.3 3.1 0.1 3.9 0.0 2.1 1.0 7.8 7.3 1.3 0.0 0.3 109.3 0.7 0.6 0.1 KRIT1 "CAM, CCM1" ENSG00000001631 "KRIT1 ankyrin repeat containing" O00522 7 92198969-92246166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 177.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049606 Supported Uncertain Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA049606: AB_2680832" "unprognostic (8.12e-2)" "unprognostic (1.11e-2)" "unprognostic (1.83e-2)" "unprognostic (3.75e-2)" "unprognostic (1.94e-1)" "unprognostic (8.93e-2)" "unprognostic (4.10e-3)" "unprognostic (1.06e-2)" "unprognostic (2.30e-3)" "unprognostic (2.18e-1)" "unprognostic (7.24e-2)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "unprognostic (2.82e-1)" "unprognostic (2.61e-1)" "unprognostic (6.18e-2)" "unprognostic (1.04e-1)" 11.4 13.6 6.5 16.2 8.9 8.5 11.8 15.8 11.3 13.1 11.7 12.1 14.5 17.1 14.1 13.3 14.0 15.7 18.9 7.4 9.5 14.1 12.1 10.7 14.7 6.7 6.9 20.3 15.9 23.8 11.4 13.6 7.9 12.1 12.6 16.3 14.1 11.2 16.3 14.0 12.2 14.1 5.7 14.7 13.7 18.8 7.8 19.4 22.4 17.5 15.8 13.6 10.8 14.2 27.6 22.0 26.8 27.4 21.2 15.9 19.6 25.5 18.3 12.0 12.3 18.8 31.1 25.9 24.6 14.8 25.9 24.1 21.9 12.7 18.5 23.0 31.4 25.2 26.6 13.2 15.2 34.9 34.5 22.3 21.8 15.0 16.9 20.7 16.2 21.8 51.4 40.5 18.9 30.7 40.6 26.0 26.6 22.4 16.3 28.4 35.5 34.1 10.8 30.9 27.4 33.5 27.7 38.3 22.9 28.2 22.0 20.6 25.1 37.3 28.2 46.9 18.3 25.6 31.1 50.4 19.5 29.6 34.4 13.4 5.5 5.4 6.5 4.0 6.6 10.8 7.5 9.5 5.6 8.5 9.5 8.3 2.2 12.0 2.9 7.6 7.7 3.3 6.5 8.9 15.8 11.3 7.4 9.5 6.7 6.9 7.9 5.7 7.8 14.2 40.6 16.0 34.3 47.0 38.9 19.9 25.7 27.3 40.5 43.7 35.5 34.3 27.6 20.0 26.8 42.3 33.3 37.3 39.2 22.0 46.9 24.0 29.7 30.0 44.1 36.2 20.4 29.2 76.9 24.2 30.0 39.7 35.7 27.9 36.7 49.4 44.6 29.7 19.3 28.6 92.6 23.1 20.3 22.1 16.2 19.5 51.3 23.4 7.2 35.6 29.9 39.9 41.2 46.8 115.4 22.1 33.1 54.2 38.0 22.4 32.2 36.3 36.9 53.1 39.5 43.8 36.8 177.1 90.1 43.1 25.1 28.0 33.0 41.8 23.7 20.5 KRT25 KRT25A ENSG00000204897 "Keratin 25" Q7Z3Z0 17 40748021-40755331 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 42 "skin 1: 112.3" "Cell type enhanced" "Detected in some" "Early spermatids: 7.8;Late spermatids: 9.2;Spermatogonia: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "RPTEC TERT1: 1.3" "Region enriched" "Detected in some" 7 "cerebellum: 8.6" "Group enriched" "Detected in some" 5 "cerebral cortex: 7.3;hippocampal formation: 4.8" "HPA053977, HPA058943" Enhanced Approved Vesicles NA NA "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA053977: AB_2682329, HPA058943: AB_2683859" "unprognostic (8.19e-2)" "unprognostic (5.89e-8)" "unprognostic (1.79e-1)" 2.6 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 112.3 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 L1TD1 "ECAT11, FLJ10884" ENSG00000240563 "LINE1 type transposase domain containing 1" Q5T7N2 1 62194849-62212328 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.5;intestine: 5.3;lymphoid tissue: 4.7;placenta: 11.6;testis: 5.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 110.2;Extravillous trophoblasts: 26.2;Intestinal goblet cells: 37.5;Spermatogonia: 53.1;Syncytiotrophoblasts: 28.2" "Cancer enriched" "Detected in some" 14 "testis cancer: 120.2" "Region enriched" "Detected in some" 4 "cerebellum: 5.5" "Immune cell enriched" "Detected in single" 13 "non-classical monocyte: 5.0" "Lineage enriched" "Detected in single" 21 "monocytes: 5.0" "Group enriched" "Detected in some" 22 "NTERA-2: 255.7;SuSa: 191.2" "Not detected" "Not detected" "HPA028501, HPA030064" Enhanced Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "HPA028501: AB_10599287, HPA030064: AB_10600538" "unprognostic (2.03e-2)" "unprognostic (7.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.86e-1)" "unprognostic (3.51e-1)" "unprognostic (2.29e-1)" "unprognostic (2.46e-1)" "unprognostic (4.03e-1)" "unprognostic (1.09e-1)" "unprognostic (9.23e-2)" "unprognostic (4.04e-2)" "unprognostic (4.61e-2)" "unprognostic (1.52e-5)" "unprognostic (3.49e-2)" "unprognostic (2.43e-1)" "unprognostic (5.75e-2)" "unprognostic (1.95e-1)" 0.2 0.3 0.1 4.7 0.5 0.0 0.2 5.5 1.3 0.3 0.0 5.3 0.1 0.1 0.3 0.0 0.1 0.2 0.0 0.3 0.0 0.3 0.0 1.5 0.2 0.2 0.1 0.2 0.0 0.0 0.1 11.6 0.3 0.1 1.2 0.0 0.4 0.1 0.0 0.1 0.3 0.3 0.0 0.9 0.1 5.8 0.0 0.2 0.4 0.0 0.1 0.1 0.2 0.6 0.0 0.0 0.2 0.1 0.0 0.0 10.1 0.1 0.0 1.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 255.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 191.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.0 0.0 0.0 0.0 0.1 0.5 5.5 1.3 0.3 0.0 0.2 0.1 0.3 0.0 0.0 0.6 0.5 6.4 13.0 0.0 1.8 0.4 0.7 0.1 0.0 2.5 1.0 2.2 0.3 0.0 7.5 0.0 6.2 110.2 2.1 3.6 0.0 0.0 0.5 0.8 0.5 2.3 10.7 0.0 0.6 0.4 26.2 3.6 0.0 1.7 1.3 2.2 0.0 0.1 7.6 3.3 0.4 37.5 0.0 1.4 1.2 1.0 1.8 4.3 0.0 0.0 0.5 0.4 1.0 0.0 0.1 0.3 1.6 18.4 1.1 0.6 0.1 0.1 6.0 3.7 0.0 1.1 2.7 0.7 53.1 0.0 0.1 28.2 1.9 2.3 9.2 0.3 L3HYPDH "C14orf149, FLJ25436" ENSG00000126790 "Trans-L-3-hydroxyproline dehydratase" Q96EM0 14 59460363-59484408 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056694 Approved Uncertain Vesicles NA NA 49000 "Cluster 48: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA056694: AB_2683210" "unprognostic (3.39e-2)" "unprognostic (5.55e-3)" "unprognostic (3.81e-2)" "unprognostic (5.86e-2)" "unprognostic (1.10e-1)" "unprognostic (5.06e-2)" "unprognostic (8.34e-2)" "unprognostic (1.16e-1)" "unprognostic (7.24e-2)" "unprognostic (9.50e-2)" "unprognostic (1.26e-3)" "unprognostic (6.60e-2)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.16e-1)" "unprognostic (2.22e-1)" "unprognostic (1.05e-1)" "unprognostic (1.14e-1)" 18.1 14.0 4.8 12.5 5.2 4.8 16.3 9.9 6.6 15.9 10.0 10.6 11.0 16.0 8.5 9.2 15.4 11.5 14.8 5.0 5.8 17.4 17.3 11.2 17.5 7.9 5.8 18.0 12.6 12.2 14.8 10.4 7.4 13.5 10.2 5.2 13.0 11.9 8.9 9.7 13.8 11.9 5.6 13.0 10.5 17.1 4.8 4.3 16.6 5.6 13.7 13.4 14.5 8.3 12.0 31.8 6.8 16.2 14.4 37.6 9.5 31.7 25.1 17.9 17.4 6.4 21.1 4.1 13.0 17.7 31.8 31.8 11.1 17.0 17.7 7.0 14.4 11.0 30.1 23.7 16.2 10.0 7.6 27.3 11.4 18.0 27.6 27.8 22.3 11.3 14.8 18.4 18.8 14.3 3.8 16.4 10.9 4.7 28.5 5.5 11.1 16.6 28.7 6.8 6.9 9.9 29.8 12.2 11.9 5.6 12.8 6.4 31.3 20.9 25.6 16.4 37.5 4.7 2.3 4.0 35.9 8.3 41.7 0.0 3.5 0.5 3.2 5.1 2.4 1.5 1.7 2.0 5.7 1.4 2.5 0.9 0.0 5.6 2.4 3.2 0.8 1.8 4.8 5.2 9.9 6.6 5.0 5.8 7.9 5.8 7.4 5.6 4.8 8.3 11.2 3.2 6.1 11.1 10.9 5.2 5.4 4.2 6.2 2.9 5.6 8.6 8.7 5.7 4.3 3.7 2.1 13.7 3.5 1.0 7.9 7.7 12.2 6.8 17.5 8.1 3.0 5.5 26.7 2.5 11.4 16.0 4.6 2.3 14.0 6.5 11.0 16.8 8.3 1.7 18.9 4.3 4.1 4.6 2.9 7.4 19.3 4.9 3.6 10.3 3.5 4.6 4.1 10.6 17.1 4.4 1.0 12.0 5.5 6.6 3.4 47.0 17.3 2.7 13.1 17.4 11.6 14.1 5.7 7.5 3.4 4.9 6.0 11.9 3.5 2.0 LAMA5 ENSG00000130702 "Laminin subunit alpha 5" O15230 20 62307955-62367312 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Cytotrophoblasts: 104.4;Glandular and luminal cells: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 114.9;CACO-2: 159.6;EFO-21: 114.4;HaCaT: 107.2;HeLa: 118.3;TIME: 138.4" "Low region specificity" "Detected in many" "HPA058389, CAB078157" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 1800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "CAB078157: AB_2665809, HPA058389: " "unprognostic (8.01e-2)" "unprognostic (2.47e-1)" "unprognostic (1.92e-2)" "unprognostic (3.42e-3)" "unprognostic (1.17e-1)" "unprognostic (9.90e-3)" "unprognostic (4.01e-3)" "unprognostic (5.45e-2)" "unprognostic (8.99e-2)" "unprognostic (1.34e-2)" "unprognostic (5.98e-3)" "unprognostic (2.98e-3)" "unprognostic (4.04e-2)" "unprognostic (9.86e-3)" "unprognostic (2.07e-1)" "unprognostic (9.76e-2)" "unprognostic (1.33e-2)" 27.1 11.8 4.7 5.0 2.2 1.3 27.0 15.2 7.0 26.3 18.9 66.7 5.3 31.3 1.2 24.5 31.8 7.9 26.6 2.4 2.0 32.7 13.2 43.9 3.0 3.2 1.9 9.3 13.9 4.8 12.1 20.0 2.5 36.7 1.2 0.6 17.8 15.4 11.0 36.0 19.9 7.3 0.6 14.0 25.1 4.6 9.3 2.7 28.6 2.8 1.9 32.6 30.2 0.4 15.1 114.9 2.2 14.8 2.7 31.0 85.9 4.2 2.2 3.3 0.6 159.6 59.1 1.3 114.4 0.1 3.6 107.2 3.1 45.8 0.2 0.3 6.5 3.8 118.3 46.1 9.9 0.0 16.6 1.6 29.6 7.9 8.0 5.7 15.0 0.0 7.0 1.7 0.0 22.3 0.1 0.4 7.3 19.3 65.9 0.2 1.4 12.8 28.6 70.3 1.1 44.5 63.2 62.2 1.2 11.6 62.0 0.9 138.4 1.6 41.2 0.7 18.9 0.8 0.2 0.6 31.7 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.7 2.2 15.2 7.0 2.4 2.0 3.2 1.9 2.5 0.6 9.3 0.4 60.2 76.9 37.1 19.9 6.9 17.1 16.0 56.8 52.9 3.6 16.7 20.8 20.5 12.8 43.9 38.6 8.4 104.4 3.9 0.6 0.0 28.6 4.3 35.5 11.7 49.6 2.4 6.1 5.9 4.5 23.3 13.0 6.1 82.0 2.5 0.9 18.9 12.7 13.1 3.3 12.7 0.3 14.2 0.6 5.4 1.3 9.9 2.2 1.8 10.3 1.1 8.2 1.0 3.5 1.3 13.2 0.1 19.5 8.5 21.9 0.0 12.2 49.6 1.8 26.3 11.0 39.4 0.6 1.7 23.4 12.6 57.3 2.2 1.7 0.6 27.5 LAMB3 "BM600-125kDa, kalinin-140kDa, LAMNB1, nicein-125kDa" ENSG00000196878 "Laminin subunit beta 3" Q13751 1 209614870-209652425 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Amelogenesis imperfecta, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.2;urinary bladder: 73.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 370.0;Basal respiratory cells: 447.6;Pancreatic endocrine cells: 853.8;Urothelial cells: 392.7" "Cancer enhanced" "Detected in all" "head and neck cancer: 223.9" "Region enriched" "Detected in many" 7 "cerebral cortex: 21.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 353.8;HaCaT: 538.2;HBEC3-KT: 1315.0;hTCEpi: 412.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA007584, HPA008069, CAB078183" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 20000 "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB078183: AB_2665825, HPA007584: , HPA008069: AB_1079228" "prognostic favorable (8.43e-4)" "unprognostic (3.08e-2)" "unprognostic (1.46e-2)" "unprognostic (2.88e-2)" "unprognostic (8.00e-2)" "unprognostic (1.60e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.62e-5)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.55e-4)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.43e-5)" "unprognostic (1.02e-1)" "unprognostic (2.38e-1)" "unprognostic (6.01e-2)" "unprognostic (4.92e-3)" 10.9 16.0 2.6 13.1 2.9 10.7 20.7 0.9 21.3 13.2 0.5 26.2 31.5 18.0 2.6 47.2 16.4 11.9 6.8 2.9 2.1 16.3 9.3 28.4 1.2 1.5 1.5 1.1 4.2 0.1 1.7 5.8 1.6 25.9 16.6 0.2 41.5 24.1 6.8 42.1 43.7 2.3 1.7 1.0 73.2 1.0 1.9 5.8 1.2 0.3 13.2 73.1 32.6 2.8 178.4 25.8 0.0 0.4 18.1 11.7 1.0 5.1 15.4 6.0 9.1 68.9 353.8 0.1 15.1 3.7 8.9 538.2 0.1 1315.0 9.1 13.1 1.4 1.1 86.9 1.1 2.4 1.0 1.3 2.6 412.8 19.1 253.4 11.7 6.4 0.1 2.5 6.7 1.9 0.3 0.2 1.2 0.6 81.0 74.0 0.2 17.1 165.4 70.9 109.0 0.5 0.5 73.9 8.5 15.4 1.0 2.0 9.7 138.3 29.1 61.3 1.0 104.6 1.7 3.4 0.4 42.2 0.8 2.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 2.6 2.9 0.9 21.3 2.9 2.1 1.5 1.5 1.6 1.7 1.9 2.8 0.4 221.2 67.7 1.6 1.2 109.7 370.0 447.6 159.9 0.3 11.5 64.4 8.4 4.3 168.5 47.8 0.0 1.1 0.4 247.5 0.0 180.5 6.0 50.8 10.0 3.5 7.8 0.4 2.5 153.0 1.4 7.5 195.7 135.0 18.4 0.2 0.4 3.9 2.0 3.3 2.3 71.7 18.3 0.3 30.0 10.9 1.8 9.9 8.8 0.0 2.1 0.4 0.0 1.0 1.7 853.8 229.1 0.7 2.1 185.0 111.9 2.3 52.2 0.3 0.0 5.3 10.4 0.3 0.6 51.7 26.0 0.5 4.0 0.0 63.1 392.7 LAMP2 CD107b ENSG00000005893 "Lysosomal associated membrane protein 2" P13473 X 120426148-120469365 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Autophagy "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 507.2;Syncytiotrophoblasts: 402.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 556.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 556.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005272, HPA029100" Supported Supported Vesicles NA NA 520000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB005272: AB_647855, HPA029100: AB_10795022" "unprognostic (2.99e-3)" "unprognostic (5.26e-2)" "unprognostic (2.66e-3)" "unprognostic (1.74e-1)" "unprognostic (3.10e-1)" "unprognostic (2.50e-2)" "unprognostic (4.84e-1)" "unprognostic (1.56e-1)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (9.73e-2)" "unprognostic (1.11e-2)" "unprognostic (2.50e-2)" "unprognostic (2.85e-1)" "unprognostic (6.78e-2)" "unprognostic (2.66e-1)" "unprognostic (5.53e-3)" 54.2 68.7 80.3 38.3 144.2 62.8 56.3 109.1 135.5 64.9 52.7 39.2 44.3 44.3 55.1 79.4 44.1 69.6 45.3 81.6 101.8 85.5 129.9 54.2 34.1 113.0 112.6 49.1 57.8 64.2 32.2 47.9 120.6 62.2 35.0 32.6 102.1 55.1 111.6 67.2 42.4 42.8 100.5 39.5 51.8 26.2 100.9 59.3 61.7 67.4 36.6 43.4 63.3 211.7 53.8 47.5 40.1 49.7 367.0 140.9 91.5 79.3 130.4 77.1 134.4 42.7 90.3 47.9 73.1 132.7 236.2 84.9 56.7 67.2 125.5 43.6 37.2 35.8 46.4 54.3 148.1 158.9 73.2 151.5 114.8 108.1 75.1 188.6 107.5 32.5 42.1 122.9 117.2 79.3 45.3 80.2 29.0 63.7 42.6 35.1 65.3 73.1 102.3 36.9 14.0 22.6 99.7 93.0 196.5 57.4 64.7 173.0 122.5 114.1 58.7 176.2 261.5 68.5 78.6 30.2 131.4 182.4 284.4 30.6 114.9 224.1 27.1 97.1 20.6 17.1 24.3 24.5 64.2 22.5 23.4 21.8 556.6 31.8 96.2 33.4 33.4 66.3 80.3 144.2 109.1 135.5 81.6 101.8 113.0 112.6 120.6 100.5 100.9 211.7 75.7 73.7 53.8 52.2 29.8 100.9 92.5 262.7 64.9 17.6 74.0 58.3 37.3 173.0 155.3 66.2 14.6 163.7 44.3 52.1 39.2 217.7 3.3 103.4 74.1 69.9 36.6 14.1 32.4 70.6 128.3 113.7 38.7 168.1 17.7 46.7 87.8 176.8 208.0 18.5 40.7 32.6 134.3 133.1 80.4 8.6 113.7 135.5 131.6 33.7 132.7 116.3 50.4 57.3 507.2 62.5 54.4 109.9 66.6 100.8 97.5 154.7 75.6 11.5 39.5 176.8 61.7 6.4 13.7 78.8 136.2 402.4 34.5 71.0 34.8 92.9 LAMP3 "CD208, DC-LAMP, DCLAMP, LAMP, TSC403" ENSG00000078081 "Lysosomal associated membrane protein 3" Q9UQV4 3 183122215-183163839 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lung: 219.7" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 486.7;monocytes: 339.6" "Cancer enhanced" "Detected in many" "lung cancer: 27.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 5.6" "Group enriched" "Detected in many" 8 "granulocytes: 5.6;T-cells: 4.8" "Group enriched" "Detected in many" 4 "EFO-21: 169.5;HDLM-2: 46.6;HHSteC: 60.4;hTCEpi: 59.1;JURKAT: 52.7" "CAB025133, HPA051467" Enhanced Enhanced Vesicles NA NA 59000 "Cluster 13: T-cells - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 38: EFO-21 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" Vesicles "CAB025133: , HPA051467: AB_2681495" "unprognostic (1.43e-3)" "unprognostic (2.06e-2)" "unprognostic (1.70e-1)" "unprognostic (2.99e-3)" "unprognostic (1.30e-2)" "unprognostic (2.15e-1)" "unprognostic (7.67e-2)" "unprognostic (8.64e-2)" "unprognostic (4.95e-2)" "prognostic favorable (9.90e-4)" "unprognostic (1.80e-3)" "unprognostic (5.80e-2)" "prognostic unfavorable (1.89e-7)" "unprognostic (3.12e-1)" "unprognostic (4.13e-2)" "unprognostic (8.35e-2)" "unprognostic (1.29e-1)" 0.7 0.6 0.2 33.1 0.4 0.8 1.3 0.3 0.2 1.4 0.0 3.2 2.7 0.7 2.6 4.4 1.1 3.9 0.3 0.2 0.1 0.6 0.9 219.7 16.1 0.2 0.1 0.3 7.8 1.9 0.5 1.9 0.1 2.7 6.8 0.6 27.2 2.5 0.2 7.0 3.1 4.3 0.2 9.0 4.1 22.7 0.3 28.1 7.5 0.2 21.5 11.2 0.9 0.0 10.7 0.3 0.2 1.7 0.1 0.1 8.7 0.2 2.8 1.8 0.5 2.8 5.3 0.1 169.5 0.9 18.9 1.5 3.7 6.4 0.2 46.6 5.9 0.0 0.3 0.4 60.4 0.0 1.4 0.9 59.1 0.1 7.4 0.0 7.6 52.7 0.4 9.9 0.2 0.2 2.5 0.4 0.3 0.9 2.7 0.0 0.0 0.8 0.2 3.4 0.7 0.4 0.8 0.3 5.0 2.1 3.4 0.4 8.3 0.0 3.0 0.4 0.2 3.5 13.2 0.5 0.0 0.1 0.1 0.3 0.0 5.6 0.2 0.0 2.4 0.1 1.8 1.1 0.0 0.2 2.3 1.3 1.3 0.6 0.0 0.0 4.8 0.7 0.2 0.4 0.3 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.3 0.0 0.2 64.1 486.7 0.0 2.0 6.0 2.9 2.4 8.6 0.0 0.3 0.6 1.2 1.5 9.5 1.8 0.0 2.9 0.1 0.1 0.0 0.6 34.3 1.3 0.2 0.5 0.0 0.4 0.7 6.1 0.4 1.0 1.5 0.8 18.9 0.4 0.0 0.0 1.3 0.0 0.6 0.2 0.0 0.0 41.1 84.9 0.6 4.8 1.8 0.0 339.6 0.0 0.0 0.0 0.1 0.6 0.0 0.0 4.1 1.6 0.1 0.0 11.5 0.0 0.0 0.4 0.3 14.0 0.5 4.0 5.7 1.2 2.3 0.0 0.5 2.2 LAMTOR4 C7orf59 ENSG00000188186 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4" Q0VGL1 7 100148907-100155944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 3294.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020998 Enhanced Supported Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA020998: AB_1845762" "prognostic favorable (2.48e-4)" "prognostic favorable (6.08e-4)" "unprognostic (1.29e-2)" "unprognostic (1.14e-1)" "unprognostic (8.21e-3)" "unprognostic (6.11e-2)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (6.17e-2)" "unprognostic (1.57e-1)" "unprognostic (2.42e-3)" "unprognostic (8.83e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-1)" "unprognostic (2.68e-1)" "unprognostic (2.45e-1)" "unprognostic (1.68e-2)" 145.5 144.7 207.2 92.8 215.4 194.6 143.4 221.1 260.4 148.0 204.4 180.6 89.4 116.7 65.9 117.5 123.1 97.7 167.4 205.7 212.3 188.5 139.1 128.0 159.0 222.1 211.3 142.7 124.2 126.7 162.7 68.1 213.3 160.8 105.8 39.9 116.8 76.2 137.5 478.7 151.0 69.0 217.6 251.9 162.2 86.6 215.8 104.8 133.8 106.0 85.5 145.8 126.7 224.1 105.9 250.9 130.2 165.4 135.2 154.9 105.7 62.1 151.0 113.1 138.9 116.9 165.7 169.1 204.7 94.2 205.7 108.9 124.0 160.0 48.1 172.4 353.2 135.2 245.0 205.4 127.4 106.4 187.1 187.3 155.4 118.5 145.6 125.7 174.9 155.3 129.9 264.4 156.1 501.0 104.0 424.7 138.7 291.1 199.9 107.4 107.1 302.8 129.1 126.9 91.6 169.0 114.3 265.8 211.3 99.0 107.1 207.0 118.3 107.1 158.6 223.7 101.7 159.1 231.2 324.2 171.0 293.5 155.9 1033.3 843.2 3121.0 299.6 795.1 251.1 541.8 377.5 312.8 570.0 475.4 381.8 307.2 3294.2 310.1 756.2 482.6 453.0 893.6 207.2 215.4 221.1 260.4 205.7 212.3 222.1 211.3 213.3 217.6 215.8 224.1 181.8 93.0 150.7 18.9 195.8 274.9 194.0 282.0 167.9 65.3 240.8 277.2 176.6 143.0 172.9 218.8 12.5 258.4 199.9 819.7 534.1 167.3 40.0 152.9 125.8 186.7 299.3 99.3 12.0 326.2 196.5 175.6 146.3 131.4 183.2 120.9 239.1 246.3 531.1 58.9 13.6 423.9 252.3 497.4 351.7 46.6 146.3 365.2 434.0 13.1 411.0 229.9 298.6 11.6 26.2 204.2 867.4 120.4 133.0 169.5 511.6 557.5 194.8 67.0 144.7 142.1 196.9 88.1 101.2 151.3 662.9 201.4 195.9 150.8 511.8 219.0 LBH ENSG00000213626 "LBH regulator of WNT signaling pathway" Q53QV2 2 30231534-30323730 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 210.6;Pancreatic endocrine cells: 298.9;Smooth muscle cells: 435.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 112.4;MAIT T-cell: 110.2;memory B-cell: 92.0;memory CD4 T-cell: 83.8;memory CD8 T-cell: 86.1;naive B-cell: 123.0;naive CD4 T-cell: 140.2;naive CD8 T-cell: 124.6;T-reg: 89.2" "Group enriched" "Detected in all" 7 "B-cells: 123.0;T-cells: 140.2" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 302.4;hTERT-RPE1: 150.6;U-2 OS: 95.1" "Low region specificity" "Detected in all" HPA034669 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA034669: AB_10600820" "unprognostic (2.13e-2)" "unprognostic (2.34e-2)" "unprognostic (1.78e-1)" "unprognostic (4.77e-3)" "unprognostic (1.23e-3)" "unprognostic (1.57e-1)" "unprognostic (2.69e-1)" "unprognostic (3.65e-3)" "unprognostic (1.93e-1)" "unprognostic (3.24e-2)" "unprognostic (2.54e-1)" "unprognostic (1.60e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.24e-4)" "unprognostic (2.25e-2)" "unprognostic (7.91e-3)" "unprognostic (1.67e-1)" 35.2 10.3 8.4 57.4 7.9 28.6 32.0 13.7 22.4 45.6 18.4 27.4 14.4 83.0 27.0 17.0 41.7 44.9 119.3 15.2 33.9 39.3 15.0 130.7 117.8 23.0 17.4 63.3 14.4 84.8 16.7 54.5 18.4 27.3 18.1 70.8 63.9 26.3 14.3 30.3 41.2 48.2 11.2 83.5 22.8 9.8 14.4 125.7 68.9 20.4 100.9 35.5 22.7 11.8 0.1 11.4 14.0 2.5 3.6 2.2 1.1 14.5 19.1 3.8 0.6 59.4 15.2 28.6 33.3 302.4 3.8 19.5 81.1 0.8 0.6 41.3 3.4 4.6 12.2 0.2 10.9 0.4 4.0 13.0 1.1 5.0 0.3 150.6 0.7 19.0 14.6 0.2 14.2 0.2 32.3 0.4 84.6 2.6 0.6 33.1 75.4 9.7 2.6 5.0 3.9 10.0 23.7 2.3 1.0 49.7 0.1 1.2 18.9 26.8 95.1 52.0 1.8 53.8 3.3 2.7 11.9 1.8 8.4 0.7 0.7 1.1 112.4 1.2 110.2 92.0 83.8 86.1 0.8 123.0 140.2 124.6 4.0 18.9 3.2 12.1 89.2 110.4 8.4 7.9 13.7 22.4 15.2 33.9 23.0 17.4 18.4 11.2 14.4 11.8 46.9 109.0 20.0 0.7 167.3 12.4 64.5 51.7 16.5 41.2 13.0 125.0 65.1 12.8 40.8 25.8 210.6 18.3 152.2 6.0 13.7 85.4 39.4 110.5 18.0 81.8 23.8 85.9 2.2 56.9 10.8 54.7 23.4 45.2 15.8 2.3 23.6 1.2 33.2 8.4 16.4 9.3 30.5 10.0 23.1 144.5 10.5 14.3 23.2 14.0 6.7 13.1 163.7 9.5 0.7 298.9 8.7 26.7 26.3 95.3 0.7 21.7 67.8 45.4 177.5 36.3 435.6 0.7 6.6 9.1 10.7 9.3 205.3 8.8 6.3 56.8 LDLRAD4 C18orf1 ENSG00000168675 "Low density lipoprotein receptor class A domain containing 4" O15165 18 13217498-13652755 "Predicted intracellular proteins, Predicted membrane proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.2;lymphoid tissue: 49.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 338.9;Inhibitory neurons: 308.5;Late spermatids: 231.5;Microglial cells: 429.1;Oligodendrocyte precursor cells: 318.7;Oligodendrocytes: 284.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 35.3;JURKAT: 37.4;MOLT-4: 131.3;REH: 31.6;U-698: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047633, HPA065246" Approved Supported Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA047633: , HPA065246: AB_2685444" "unprognostic (2.52e-1)" "unprognostic (4.31e-3)" "unprognostic (5.30e-2)" "unprognostic (1.23e-1)" "unprognostic (1.64e-1)" "unprognostic (3.94e-3)" "unprognostic (9.73e-2)" "unprognostic (2.26e-2)" "unprognostic (2.21e-2)" "unprognostic (2.92e-2)" "unprognostic (2.30e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (4.58e-4)" "unprognostic (2.51e-2)" "unprognostic (4.38e-2)" "unprognostic (6.58e-2)" "unprognostic (8.18e-2)" 6.5 4.3 13.9 7.3 38.0 9.7 6.3 34.6 25.9 7.8 37.4 5.8 6.1 12.4 0.9 3.9 11.3 4.6 16.6 10.7 16.4 4.0 10.3 4.6 6.5 46.1 33.2 2.3 3.3 2.9 6.9 6.2 38.6 8.6 2.1 7.0 3.0 5.3 15.4 4.2 7.2 5.7 27.3 5.6 5.0 9.2 48.2 49.3 4.4 9.5 3.8 5.3 5.3 39.6 0.2 0.3 1.4 0.8 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.1 0.1 2.7 1.6 0.8 0.4 0.0 0.0 0.0 17.1 1.7 35.3 7.0 1.2 0.0 1.7 0.9 0.0 0.0 0.0 0.0 0.0 0.4 37.4 0.4 0.7 0.0 2.6 131.3 1.1 2.9 0.3 8.9 31.6 0.1 1.2 0.0 1.1 2.4 3.9 0.5 2.2 0.0 1.9 3.8 4.7 2.4 1.3 11.5 0.2 1.9 5.6 0.4 26.1 0.0 6.9 6.4 12.8 7.0 2.1 6.5 7.7 5.7 5.2 5.8 5.6 3.9 4.4 8.2 7.6 12.1 9.1 8.5 5.9 3.4 4.5 13.9 38.0 34.6 25.9 10.7 16.4 46.1 33.2 38.6 27.3 48.2 39.6 19.4 3.2 4.7 143.3 79.2 10.5 2.7 0.8 0.0 5.4 26.0 16.9 18.4 0.0 5.0 1.8 70.9 0.6 21.0 6.8 1.9 5.1 135.2 16.3 22.0 16.6 58.7 7.6 338.9 3.6 0.7 16.5 13.3 7.8 23.5 7.6 25.0 24.4 21.1 0.0 308.5 9.1 2.0 27.4 160.5 231.5 11.1 56.2 14.2 429.1 13.6 4.7 3.1 318.7 284.9 0.7 2.6 24.5 11.7 13.5 15.6 2.3 13.7 18.7 6.6 2.3 9.7 5.4 4.9 0.4 7.7 1.6 66.0 0.2 8.8 3.2 LHFPL3 LHFPL4 ENSG00000187416 "LHFPL tetraspan subfamily member 3" Q86UP9 7 104328700-104907232 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 30.5;retina: 23.6" "Cell type enriched" "Detected in some" 19 "Oligodendrocyte precursor cells: 4790.3" "Cancer enriched" "Detected in some" 12 "glioma: 27.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.6;SH-SY5Y: 2.1;SK-BR-3: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069691 Approved Vesicles No NA "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA069691: AB_2686171" "unprognostic (1.20e-2)" "unprognostic (6.91e-2)" "unprognostic (4.59e-3)" "unprognostic (5.03e-2)" "unprognostic (2.27e-2)" "unprognostic (2.22e-1)" "unprognostic (1.07e-1)" "unprognostic (6.96e-2)" "unprognostic (5.81e-2)" "unprognostic (5.99e-3)" "unprognostic (8.50e-3)" "unprognostic (3.07e-1)" "unprognostic (1.33e-1)" 0.0 0.1 20.2 0.1 10.8 0.0 0.0 13.1 7.4 3.3 0.0 0.7 1.4 0.6 0.0 0.0 0.3 0.0 0.0 5.4 15.5 1.4 0.0 1.5 0.0 7.3 14.2 0.1 0.9 0.0 0.0 0.0 7.5 0.2 0.1 23.6 0.0 0.0 0.0 0.2 1.2 0.0 10.2 0.4 0.3 0.1 30.5 0.0 0.0 0.0 0.1 0.0 0.2 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.1 0.0 1.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 10.8 13.1 7.4 5.4 15.5 7.3 14.2 7.5 10.2 30.5 9.5 0.0 0.0 0.5 3.6 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.2 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.3 0.2 7.7 0.1 0.0 0.0 31.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 245.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.8 0.0 1.3 0.0 4790.3 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 7.3 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 LHFPL5 "DFNB67, dJ510O8.8, MGC33835, Tmhs" ENSG00000197753 "LHFPL tetraspan subfamily member 5" Q8TAF8 6 35797206-35845397 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.8;epididymis: 12.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 13.5;Excitatory neurons: 8.0;Glandular and luminal cells: 2.8;Inhibitory neurons: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029421, HPA055110" Uncertain Approved Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA029421: , HPA055110: AB_2682697" "unprognostic (2.35e-1)" "unprognostic (6.45e-2)" "unprognostic (2.41e-2)" "unprognostic (1.22e-3)" "unprognostic (1.96e-1)" "unprognostic (1.78e-1)" "unprognostic (4.89e-3)" "unprognostic (2.96e-3)" "unprognostic (2.46e-2)" "unprognostic (1.47e-8)" "unprognostic (5.53e-2)" "unprognostic (1.70e-1)" "unprognostic (2.15e-1)" "unprognostic (1.41e-1)" 0.9 1.1 4.1 2.7 4.6 18.8 0.8 4.8 5.6 0.3 0.3 0.9 3.0 1.5 12.4 1.3 0.6 1.7 0.7 3.6 2.6 0.6 0.8 1.0 2.8 0.0 0.3 1.1 5.6 0.3 0.5 1.3 0.2 1.0 0.7 8.2 2.4 0.4 1.4 7.6 2.5 0.3 0.0 2.2 1.7 1.5 1.9 0.5 1.4 0.2 0.6 0.6 0.0 2.7 2.3 1.5 3.0 3.1 0.2 0.6 4.6 1.6 0.3 0.1 0.4 2.7 2.0 3.6 1.2 0.6 1.9 2.9 0.2 0.8 0.3 1.6 2.6 3.2 5.3 4.0 0.0 3.4 2.2 0.5 0.3 0.3 0.4 2.1 0.2 3.6 3.1 5.1 0.9 1.9 2.5 6.2 2.6 0.7 1.5 2.2 1.1 2.0 0.7 5.6 3.4 1.9 1.6 2.3 1.0 2.9 2.4 1.9 2.6 3.1 1.7 2.5 2.4 3.2 3.0 3.1 1.1 3.6 1.6 2.9 0.6 0.5 0.3 0.3 0.3 0.5 0.3 0.3 0.1 0.9 0.4 0.5 3.3 0.6 0.4 0.7 0.4 0.1 4.1 4.6 4.8 5.6 3.6 2.6 0.0 0.3 0.2 0.0 1.9 2.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 1.3 0.7 0.3 0.0 0.4 8.0 0.2 0.0 0.2 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 LMBRD1 "bA810I22.1, C6orf209, cblF, FLJ11240" ENSG00000168216 "LMBR1 domain containing 1" Q9NUN5 6 69672757-69867236 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Endocytosis, Gastrulation, Host-virus interaction, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 21.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016491, HPA019547" Uncertain Supported Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 59: Non-specific - Transcription" Vesicles "HPA016491: , HPA019547: AB_2281256" "unprognostic (1.44e-1)" "unprognostic (3.84e-2)" "unprognostic (7.67e-2)" "unprognostic (7.64e-2)" "unprognostic (2.41e-1)" "unprognostic (5.37e-2)" "unprognostic (2.26e-1)" "unprognostic (4.39e-2)" "unprognostic (2.19e-1)" "unprognostic (1.97e-1)" "unprognostic (2.22e-1)" "unprognostic (1.47e-1)" "prognostic favorable (1.07e-7)" "unprognostic (7.99e-2)" "unprognostic (1.67e-1)" "unprognostic (2.60e-2)" "unprognostic (2.68e-2)" 33.3 49.4 10.3 11.5 10.8 4.2 31.4 20.7 17.0 28.9 13.3 26.4 13.5 22.5 27.7 25.7 26.3 16.0 27.7 11.1 11.5 53.0 42.9 27.9 12.1 13.6 11.9 34.5 36.5 31.7 26.5 17.2 12.3 19.1 20.5 10.7 33.2 20.0 28.8 28.1 28.6 12.7 11.4 21.8 29.6 10.4 10.2 9.1 35.1 13.1 16.8 30.1 29.4 16.1 3.8 3.8 6.0 10.2 16.5 23.7 17.9 2.2 7.1 2.6 5.6 4.8 8.2 6.5 9.2 8.8 5.8 7.5 3.8 9.8 2.4 16.3 11.9 6.2 4.9 7.8 13.7 3.4 8.7 7.6 9.6 0.8 5.7 19.1 7.4 5.5 9.4 6.1 6.0 8.1 2.5 4.7 4.6 8.5 4.8 0.3 15.4 37.8 17.0 13.8 5.5 8.5 0.9 7.0 13.3 3.0 4.6 25.3 1.1 3.9 4.6 4.3 2.8 8.8 5.5 2.8 2.3 4.0 12.3 6.5 2.2 3.9 2.0 2.5 2.5 12.1 2.9 1.9 1.7 21.0 3.1 2.3 11.4 2.6 4.8 2.2 3.7 2.1 10.3 10.8 20.7 17.0 11.1 11.5 13.6 11.9 12.3 11.4 10.2 16.1 49.7 64.1 38.3 82.3 93.4 29.1 41.9 45.2 71.2 73.7 39.2 25.4 40.6 50.1 56.0 58.8 110.5 69.6 36.2 79.0 19.6 49.0 28.8 48.3 22.7 41.1 18.7 18.5 119.2 49.6 59.2 56.1 36.7 61.7 40.5 15.7 44.6 60.5 42.1 55.5 144.6 37.6 44.7 66.9 36.3 9.3 35.4 52.0 32.0 79.6 49.3 56.3 28.8 122.2 156.6 42.0 51.0 33.8 82.7 19.6 78.7 64.1 65.5 90.8 26.3 36.4 33.9 22.5 16.9 43.4 38.1 77.4 43.2 26.9 31.7 34.2 LOXL4 "FLJ21889, LOXC" ENSG00000138131 "Lysyl oxidase like 4" Q96JB6 10 98247690-98268194 "Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Basal respiratory cells: 141.0" "Cancer enhanced" "Detected in all" "melanoma: 44.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "BJ hTERT+: 249.7;CAPAN-2: 301.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033876, HPA037609" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB033876: AB_2135101, HPA037609: AB_2675579" "unprognostic (9.91e-3)" "unprognostic (3.97e-2)" "unprognostic (1.81e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (7.71e-2)" "unprognostic (1.75e-2)" "unprognostic (8.38e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (9.57e-4)" "unprognostic (2.51e-1)" "unprognostic (4.97e-2)" "unprognostic (5.25e-2)" "unprognostic (5.77e-3)" "unprognostic (1.28e-1)" "unprognostic (6.10e-2)" "unprognostic (7.40e-3)" 8.2 2.4 0.7 1.6 0.9 0.5 11.9 1.1 0.7 11.8 2.3 10.4 1.9 7.0 3.0 2.0 7.8 1.8 3.0 0.8 1.2 6.6 6.0 4.4 0.4 1.3 1.3 7.1 6.6 1.2 1.9 5.8 1.3 6.6 1.8 2.6 19.6 10.8 8.3 4.0 3.2 7.6 1.0 2.7 2.9 5.5 1.0 1.4 7.0 1.5 0.7 5.0 7.4 1.0 0.0 1.6 0.1 0.3 6.9 29.5 0.9 32.1 249.7 2.6 26.6 5.4 301.6 0.1 28.4 25.1 1.1 0.3 0.1 0.0 2.2 0.0 0.2 0.0 4.4 13.3 6.7 0.0 0.0 3.3 0.0 4.4 0.0 0.4 0.1 0.0 0.3 0.0 0.4 0.0 0.0 2.3 0.6 0.1 0.5 0.1 2.9 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 8.7 0.2 0.7 0.7 0.2 53.7 3.2 1.1 0.0 0.0 0.2 0.5 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.7 0.9 1.1 0.7 0.8 1.2 1.3 1.3 1.3 1.0 1.0 1.0 0.3 6.4 1.5 0.7 0.3 0.9 2.1 141.0 0.0 0.4 6.5 6.5 1.6 4.3 17.5 31.3 0.0 0.2 1.7 0.1 0.0 11.1 0.3 1.5 1.2 0.9 0.0 0.0 0.1 0.5 0.4 6.0 0.0 4.2 1.3 1.1 2.2 0.4 0.2 0.0 0.1 0.2 8.2 0.0 2.1 0.4 4.1 0.2 0.0 9.4 0.0 5.4 0.0 0.0 0.0 3.0 0.0 1.5 0.3 7.9 0.0 0.4 6.3 0.1 0.0 5.2 2.2 0.1 0.2 0.1 0.9 0.4 0.2 0.7 0.0 3.4 LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967259 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 937.4;heart muscle: 407.8" "Cell type enhanced" "Detected in many" "Adipocytes: 453.0;Cardiomyocytes: 489.0;Granulosa cells: 495.2;Horizontal cells: 206.9;Sertoli cells: 236.7" "Cancer enhanced" "Detected in all" "glioma: 39.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 6 "monocytes: 4.2" "Cell line enriched" "Detected in some" 5 "AF22: 391.6" "Region enhanced" "Detected in many" "basal ganglia: 45.3" "Group enriched" "Detected in all" 5 "basal ganglia: 79.2;spinal cord: 59.3" HPA048749 Supported Vesicles "Secreted to blood" NA NA 4200000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA048749: AB_2680511" "unprognostic (5.52e-2)" "unprognostic (3.16e-1)" "unprognostic (6.41e-2)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-4)" "unprognostic (1.05e-1)" "unprognostic (6.78e-2)" "unprognostic (8.20e-2)" "unprognostic (2.54e-2)" "unprognostic (5.28e-1)" "unprognostic (1.18e-1)" "unprognostic (4.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.07e-4)" 937.4 15.9 6.8 9.1 53.2 0.9 255.4 20.3 12.2 2.7 8.9 12.0 1.5 3.7 0.5 2.8 2.7 8.6 407.8 10.7 9.5 19.1 0.7 62.1 8.5 7.4 7.7 10.6 6.3 181.5 4.1 14.7 7.9 3.8 5.8 11.1 24.4 64.7 86.4 8.3 13.3 4.1 5.5 1.6 8.4 1.0 11.5 4.3 10.6 127.3 2.8 6.1 4.7 8.8 0.0 0.0 391.6 0.1 8.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.8 0.0 0.0 0.1 0.3 0.0 71.5 0.0 0.2 8.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.1 0.7 9.6 0.0 0.0 0.0 0.0 68.4 0.0 0.0 8.4 0.2 0.0 0.0 0.1 13.5 0.0 1.8 0.0 0.0 8.1 0.0 3.5 0.0 0.1 0.1 0.1 0.1 32.6 0.0 0.9 0.7 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 6.8 53.2 20.3 12.2 10.7 9.5 7.4 7.7 7.9 5.5 11.5 8.8 453.0 12.8 104.9 1.0 0.4 1.5 0.1 0.0 0.6 2.8 114.7 5.7 489.0 0.0 0.6 0.0 2.1 0.4 0.9 0.1 15.6 0.0 0.8 0.2 2.5 56.1 0.0 0.0 1.9 0.0 0.7 13.6 0.0 0.3 6.3 495.2 2.9 0.0 108.5 206.9 0.4 1.0 0.0 14.8 4.2 1.3 1.2 38.2 14.2 1.9 2.0 2.3 0.0 9.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.4 2.9 2.7 236.7 91.4 68.1 0.4 0.2 0.2 0.6 0.4 2.3 4.3 2.8 0.1 LRG1 LRG ENSG00000171236 "Leucine rich alpha-2-glycoprotein 1" P02750 19 4536402-4540036 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "liver: 944.2" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 793.0" "Cancer enriched" "Detected in many" 9 "liver cancer: 160.9" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 19 "neutrophil: 285.2" "Lineage enriched" "Detected in many" 44 "granulocytes: 285.2" "Cell line enhanced" "Detected in many" "Hep G2: 15.4;SK-BR-3: 15.7;THP-1: 26.2;U-937: 48.7" "Low region specificity" "Detected in single" "HPA001888, HPA001889" Enhanced Approved Vesicles "Secreted to blood" NA NA 21000000000 42000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA001888: AB_1079276, HPA001889: AB_1079275" "unprognostic (5.54e-3)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "unprognostic (1.42e-1)" "unprognostic (2.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-2)" "unprognostic (1.46e-3)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.66e-6)" "unprognostic (4.06e-2)" "unprognostic (1.45e-1)" "prognostic favorable (3.49e-4)" "unprognostic (2.60e-2)" 7.2 4.5 0.6 17.8 0.5 31.4 4.3 1.2 2.6 8.7 1.1 7.3 6.7 1.9 5.9 22.7 10.0 15.5 1.2 0.6 0.6 9.8 944.2 7.8 0.8 0.7 0.7 1.5 44.1 0.1 1.6 1.9 1.9 4.4 4.7 0.1 20.9 6.2 1.0 4.8 3.3 2.2 0.5 16.2 13.6 0.3 0.9 1.2 1.3 1.4 6.5 13.3 3.8 0.9 10.8 0.1 0.0 0.0 0.0 0.1 8.0 0.0 0.0 0.0 0.0 1.0 8.0 3.6 13.3 0.0 0.5 1.4 0.0 1.7 0.1 13.4 0.4 0.3 0.2 15.4 0.0 0.4 13.9 4.1 0.0 0.0 0.0 0.0 0.1 0.0 9.6 0.2 0.0 0.6 0.0 11.3 0.2 8.2 0.0 0.1 0.3 11.3 1.0 2.0 0.0 0.0 0.1 15.7 0.1 1.3 4.8 26.2 0.3 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.0 48.7 0.0 2.4 6.4 15.0 0.1 2.0 0.1 0.4 0.3 0.1 1.6 0.4 0.1 0.1 285.2 0.2 1.3 0.2 1.1 2.2 0.6 0.5 1.2 2.6 0.6 0.6 0.7 0.7 1.9 0.5 0.9 0.9 13.4 12.8 54.3 0.0 3.3 8.0 33.1 56.8 18.2 0.1 14.2 2.5 0.5 60.1 50.2 14.7 0.0 0.8 0.5 44.7 1.9 112.7 0.0 38.0 1.8 24.7 4.9 13.2 0.0 64.1 12.4 3.0 31.6 17.3 12.0 0.2 38.2 793.0 6.7 1.7 0.0 26.3 32.6 19.9 5.0 0.0 0.0 14.7 1.8 0.0 7.3 0.1 0.0 0.0 0.0 40.6 11.9 0.0 1.7 4.5 10.8 4.9 76.1 0.1 0.0 2.3 3.3 0.0 0.2 9.0 5.8 1.4 1.9 3.4 27.6 30.2 LRP1B "LRP-DIT, LRPDIT" ENSG00000168702 "LDL receptor related protein 1B" Q9NZR2 2 140231423-142131016 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.5" "Cell type enhanced" "Detected in some" "Astrocytes: 2119.8;Excitatory neurons: 3755.5;Inhibitory neurons: 2917.8;Oligodendrocyte precursor cells: 5568.9;Oligodendrocytes: 1203.1" "Cancer enhanced" "Detected in some" "breast cancer: 0.8;glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.5;HEK 293: 1.7;U-138 MG: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069094, HPA074788" Approved Approved Vesicles NA NA 370000 "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA069094: AB_2686082, HPA074788: AB_2797273" "unprognostic (5.31e-4)" "unprognostic (3.68e-2)" "unprognostic (2.61e-1)" "unprognostic (7.36e-4)" "unprognostic (5.19e-2)" "unprognostic (1.26e-1)" "unprognostic (2.00e-2)" "unprognostic (3.49e-1)" "unprognostic (3.75e-1)" "unprognostic (7.02e-3)" "unprognostic (1.64e-3)" "unprognostic (1.05e-1)" "unprognostic (2.94e-3)" "unprognostic (4.85e-3)" "unprognostic (1.52e-1)" "unprognostic (1.66e-2)" "unprognostic (1.36e-1)" 3.1 1.4 18.6 0.0 22.5 0.0 1.6 7.2 18.7 0.3 0.0 0.3 0.0 0.0 2.2 0.0 0.3 0.1 0.3 21.5 8.7 0.4 0.2 0.1 0.0 6.8 9.4 0.6 0.1 0.1 1.9 0.0 8.2 0.9 0.0 2.6 0.6 1.0 4.4 0.4 0.1 0.0 3.3 0.0 0.4 0.3 11.5 0.2 5.6 3.5 0.0 0.1 0.9 19.8 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.1 0.2 1.7 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 18.6 22.5 7.2 18.7 21.5 8.7 6.8 9.4 8.2 3.3 11.5 19.8 1.4 0.0 0.0 2119.8 0.0 0.3 0.5 0.0 3.4 14.9 0.2 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.9 0.1 1.7 0.2 0.0 0.0 3755.5 0.0 0.0 9.1 0.0 0.5 0.0 0.1 0.0 0.5 0.0 0.0 2917.8 0.0 0.0 0.0 0.5 5.4 1.2 0.1 0.0 142.4 0.0 2.4 0.0 5568.9 1203.1 0.0 0.0 0.7 0.0 0.3 0.0 0.2 0.0 0.8 0.0 1.1 0.4 0.2 0.3 0.2 0.3 0.0 0.1 0.2 0.0 0.8 LRRC24 LRRC14OS ENSG00000254402 "Leucine rich repeat containing 24" Q50LG9 8 144522388-144527033 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 13.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 103.2;Cone photoreceptor cells: 73.0;Horizontal cells: 30.3;Late spermatids: 69.0;Rod photoreceptor cells: 86.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.6;SCLC-21H: 2.7;SH-SY5Y: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028171, HPA052250" Enhanced Approved Vesicles NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA028171: AB_2672504, HPA052250: AB_2681774" "unprognostic (1.75e-1)" "unprognostic (5.76e-2)" "unprognostic (2.33e-3)" "unprognostic (3.63e-2)" 2.1 3.6 6.2 0.1 6.4 0.3 2.3 4.1 7.8 5.0 0.8 3.1 0.3 4.4 0.2 3.8 5.4 0.1 1.9 5.4 9.0 3.7 3.2 2.7 0.2 10.0 8.3 6.1 3.0 1.2 13.3 0.2 6.5 11.5 0.1 1.4 1.5 0.6 1.2 1.8 2.6 0.2 4.5 2.1 2.4 3.0 5.3 0.3 3.4 0.1 0.0 2.9 3.2 4.8 0.2 0.5 0.4 0.9 0.4 0.3 1.1 0.3 0.4 0.4 0.3 0.1 1.0 0.5 2.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 1.3 0.3 0.6 0.2 0.3 0.0 0.6 0.4 0.2 0.3 0.0 0.2 0.2 0.5 0.6 0.1 0.0 2.6 0.7 1.0 0.1 0.1 0.5 1.1 0.0 0.4 0.1 0.3 2.7 7.4 0.2 0.1 0.2 0.0 2.3 0.8 0.0 0.1 0.7 0.3 0.1 0.5 0.1 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 6.4 4.1 7.8 5.4 9.0 10.0 8.3 6.5 4.5 5.3 4.8 0.7 0.0 2.3 8.5 1.0 0.9 0.5 0.0 0.0 103.2 2.3 2.8 0.0 1.5 0.7 1.8 73.0 0.6 0.5 2.1 3.9 0.2 23.7 1.5 1.5 1.1 10.7 0.8 3.8 0.2 0.4 1.4 3.1 1.6 0.0 4.8 0.7 3.1 0.5 30.3 6.5 2.7 0.0 0.8 1.7 69.0 2.8 0.8 5.4 1.0 0.2 18.6 1.0 4.5 2.2 0.3 1.9 3.0 1.2 1.8 1.9 3.6 0.1 86.2 0.0 2.9 1.9 11.2 3.5 1.7 0.4 0.4 0.6 8.4 1.9 0.9 LRRC37A KIAA0563 ENSG00000176681 "Leucine rich repeat containing 37A" A6NMS7 17 46292733-46337794 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.1" "Cell type enhanced" "Detected in some" "Astrocytes: 55.5;Excitatory neurons: 86.9;Inhibitory neurons: 82.8;Microglial cells: 49.6;Oligodendrocyte precursor cells: 60.8;Oligodendrocytes: 48.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 3.7;HeLa: 2.0" "HPA042121, HPA043056, HPA045090, HPA049080" Supported Approved Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA042121: AB_2677858, HPA043056: AB_2678294, HPA045090: AB_2679211, HPA049080: AB_2680624" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.22e-2)" "unprognostic (3.75e-2)" "unprognostic (6.02e-1)" "unprognostic (2.94e-1)" "unprognostic (1.78e-1)" "unprognostic (3.06e-2)" "unprognostic (5.23e-2)" "unprognostic (5.20e-2)" "unprognostic (8.22e-2)" "unprognostic (2.05e-1)" "unprognostic (2.65e-3)" "unprognostic (3.37e-1)" "unprognostic (4.35e-1)" "unprognostic (1.70e-2)" "unprognostic (4.30e-2)" 2.0 1.7 1.0 0.7 1.0 0.5 2.1 1.2 3.1 3.1 0.9 2.3 0.0 2.1 0.0 2.0 3.2 0.1 1.5 1.0 1.1 2.2 1.7 2.2 0.5 1.0 0.9 2.3 2.2 0.3 3.7 0.2 1.1 2.8 0.2 1.6 2.3 0.2 4.7 3.7 2.4 0.1 0.8 2.6 2.0 11.1 1.3 0.4 2.5 0.4 0.3 2.5 2.6 1.1 0.1 0.1 0.7 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.1 1.7 0.1 3.7 0.1 0.1 1.2 0.1 0.0 0.0 0.0 0.2 0.5 0.2 2.0 1.3 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.4 0.0 0.1 0.3 0.5 0.0 0.0 1.3 1.3 0.8 0.0 0.8 0.2 0.4 0.1 0.3 0.0 0.0 0.2 1.7 0.6 0.6 1.0 0.1 0.1 1.5 1.2 0.2 0.6 1.1 1.0 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.2 0.2 0.1 0.0 1.0 1.0 1.2 3.1 1.0 1.1 1.0 0.9 1.1 0.8 1.3 1.1 0.7 3.2 0.5 55.5 1.0 0.1 0.4 0.0 0.6 0.5 0.2 0.0 4.3 0.0 0.2 0.0 0.0 0.1 0.9 1.4 1.9 0.1 21.0 0.3 0.7 0.4 1.2 0.0 86.9 0.4 0.0 0.6 2.0 0.4 1.3 0.4 0.4 0.1 0.3 0.0 82.8 1.1 0.0 2.2 0.8 2.8 0.0 0.6 0.0 49.6 0.1 0.2 0.0 60.8 48.1 0.2 0.8 0.4 0.4 0.1 1.9 0.2 0.9 0.9 0.0 0.7 0.6 1.3 1.1 0.4 0.1 0.1 1.4 0.1 1.1 0.1 LRRC37A2 FLJ45049 ENSG00000238083 "Leucine rich repeat containing 37 member A2" A6NM11 17 46511511-46555650 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 6.5" "Cell type enhanced" "Detected in many" "Astrocytes: 34.0;Early spermatids: 46.8;Excitatory neurons: 55.9;Inhibitory neurons: 55.5;Microglial cells: 34.7;Oligodendrocyte precursor cells: 47.7;Oligodendrocytes: 46.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.3;THP-1: 1.2" "HPA042121, HPA043056, HPA045090, HPA049080" Supported Approved Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA042121: AB_2677858, HPA043056: AB_2678294, HPA045090: AB_2679211, HPA049080: AB_2680624" "unprognostic (1.59e-2)" "unprognostic (3.75e-2)" "unprognostic (8.96e-2)" "unprognostic (6.35e-2)" "unprognostic (2.53e-1)" "unprognostic (2.97e-3)" "unprognostic (4.61e-3)" "unprognostic (1.63e-1)" "unprognostic (6.47e-2)" "unprognostic (2.01e-1)" "unprognostic (1.55e-3)" "unprognostic (8.00e-2)" "unprognostic (3.02e-7)" "unprognostic (8.40e-2)" "unprognostic (2.82e-1)" "unprognostic (1.52e-1)" "unprognostic (5.77e-2)" 0.5 0.1 0.2 0.2 0.2 0.5 0.5 0.8 0.2 0.3 0.1 0.3 0.0 0.3 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.6 0.1 0.3 0.2 0.4 0.1 0.2 0.2 0.4 0.7 0.0 0.3 0.3 0.3 0.4 0.2 0.3 0.6 0.6 0.4 0.2 0.0 0.1 0.2 6.5 0.4 0.4 0.3 0.2 0.2 0.4 0.3 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.6 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.0 0.4 1.2 0.2 0.7 0.6 0.0 0.2 0.4 0.3 0.1 0.0 0.3 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.2 0.1 0.1 0.4 0.1 0.3 0.0 0.4 0.0 2.5 22.4 14.6 34.0 3.8 1.5 4.2 1.0 2.2 7.1 2.6 2.2 2.5 1.5 5.1 0.0 12.5 1.1 8.5 2.3 0.0 2.6 46.8 8.3 5.6 3.0 1.8 0.8 55.9 0.9 0.9 3.2 1.5 5.5 11.4 5.4 1.4 0.8 1.4 13.5 55.5 2.5 0.0 1.2 1.8 11.5 3.4 3.5 0.0 34.7 1.8 2.4 3.1 47.7 46.4 1.0 2.7 1.9 3.0 2.5 1.2 0.4 11.3 8.8 13.1 4.1 2.7 7.9 3.0 1.4 2.3 0.7 6.1 1.7 1.6 2.9 LRRC37A3 "FLJ34306, KIAA0563" ENSG00000176809 "Leucine rich repeat containing 37 member A3" O60309 17 64854312-64919480 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 28.9" "Cell type enhanced" "Detected in many" "Astrocytes: 82.6;Excitatory neurons: 143.1;Inhibitory neurons: 161.3;Microglial cells: 75.9;Oligodendrocyte precursor cells: 110.1;Oligodendrocytes: 99.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA042121, HPA043056, HPA045090" Supported Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA042121: AB_2677858, HPA043056: AB_2678294, HPA045090: AB_2679211" "unprognostic (2.28e-1)" "unprognostic (1.68e-1)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (2.92e-2)" "unprognostic (3.38e-1)" "unprognostic (1.84e-2)" "unprognostic (2.27e-1)" "unprognostic (3.29e-1)" "unprognostic (1.80e-2)" "unprognostic (5.31e-6)" "unprognostic (1.83e-1)" "prognostic unfavorable (3.25e-6)" "unprognostic (2.26e-1)" "unprognostic (4.89e-2)" "unprognostic (5.18e-2)" "unprognostic (7.43e-3)" 4.1 4.2 12.2 2.1 11.5 4.0 5.0 15.4 16.1 6.3 11.5 3.8 1.5 4.2 9.3 3.4 7.6 3.8 3.7 11.2 13.5 14.9 4.3 4.2 2.6 12.2 11.9 7.8 4.7 2.7 22.3 2.6 12.0 8.2 2.1 18.8 3.2 3.3 4.2 4.2 3.0 2.3 9.7 4.4 3.0 28.9 14.7 2.0 17.1 1.0 1.6 3.5 4.4 11.6 2.2 4.4 4.1 9.3 4.6 2.8 2.9 3.0 2.5 2.0 2.3 1.9 3.3 2.2 1.4 1.6 3.6 1.9 1.1 0.9 0.9 2.9 4.2 7.0 3.1 1.3 1.8 2.5 1.6 1.9 1.9 1.5 0.6 9.2 1.4 2.8 1.4 1.2 1.5 6.0 1.3 4.5 3.1 0.5 1.2 1.5 2.2 1.0 4.3 2.0 2.7 10.2 1.2 5.3 1.3 11.6 2.4 4.7 5.1 3.7 1.1 1.5 1.7 1.8 1.9 1.7 2.6 10.7 6.3 2.7 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.6 0.3 0.3 0.7 1.1 0.4 0.8 0.3 0.1 12.2 11.5 15.4 16.1 11.2 13.5 12.2 11.9 12.0 9.7 14.7 11.6 2.0 0.0 2.2 82.6 1.8 1.8 1.6 0.5 1.8 11.4 1.6 1.5 2.8 1.5 1.9 1.8 4.2 1.3 1.9 1.5 1.9 3.0 37.9 4.9 2.7 3.6 1.2 0.4 143.1 1.3 0.2 1.9 1.1 2.3 2.5 4.6 4.6 1.0 1.5 25.2 161.3 1.1 0.0 0.9 0.7 8.6 2.1 1.4 1.8 75.9 1.4 3.7 2.1 110.1 99.3 0.7 1.7 3.0 1.8 1.2 0.7 6.9 6.9 4.1 6.6 4.1 1.7 7.3 1.8 1.0 1.0 1.0 1.4 1.3 1.1 1.4 LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lung: 52.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 502.2;Excitatory neurons: 92.0;monocytes: 133.1;Oligodendrocyte precursor cells: 256.9" "Cancer enhanced" "Detected in many" "renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.2" "Lineage enriched" "Detected in many" 8 "granulocytes: 58.2" "Cell line enhanced" "Detected in some" "A549: 4.6;ASC TERT1: 5.6;BJ hTERT+: 3.2;RPTEC TERT1: 7.8;T-47d: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Supported Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" Vesicles "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favorable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" 4.8 3.1 1.1 10.1 1.9 9.0 2.6 0.9 2.1 5.1 1.2 4.3 0.6 4.8 1.9 7.0 4.1 6.2 3.9 1.3 1.1 10.9 5.6 52.4 6.8 1.7 1.1 5.4 3.6 8.4 2.1 1.2 1.4 2.6 1.8 1.5 3.5 2.0 5.5 2.1 3.6 4.0 1.1 10.8 2.1 0.8 1.2 2.5 2.9 7.9 5.4 4.5 5.5 1.9 0.0 4.6 0.0 0.0 2.3 5.6 0.0 1.3 3.2 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.0 0.6 0.4 0.0 2.1 0.4 0.0 0.0 2.5 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.3 0.0 0.5 2.7 0.1 3.1 1.5 1.0 0.4 0.5 0.6 0.4 0.0 0.0 0.0 1.3 0.0 1.7 0.0 7.2 2.2 0.0 5.2 0.0 1.8 0.0 0.0 2.1 1.7 0.0 0.0 58.2 0.0 6.9 0.3 0.0 1.3 1.1 1.9 0.9 2.1 1.3 1.1 1.7 1.1 1.4 1.1 1.2 1.9 7.4 32.1 502.2 17.3 29.9 2.4 1.8 0.4 2.8 8.6 1.3 1.4 7.8 5.7 17.3 27.6 0.0 0.0 1.9 0.0 1.9 1.3 0.5 0.4 2.6 7.0 0.0 2.1 92.0 2.7 0.1 16.1 0.5 0.4 13.9 2.7 13.2 8.2 4.6 47.1 28.0 0.0 0.0 55.8 8.7 1.2 19.0 52.2 12.4 73.1 133.1 8.6 3.1 256.9 3.1 0.8 1.1 12.0 2.8 0.6 0.0 22.5 3.4 1.0 0.0 22.5 4.8 0.3 1.0 12.6 3.1 0.4 3.4 11.2 0.0 0.7 LSM14B "bA11M20.3, C20orf40, FAM61B, FLJ25473, FT005, LSM13, RAP55B" ENSG00000149657 "LSM family member 14B" Q9BX40 20 62122461-62135374 "Predicted intracellular proteins" "Translation regulation" "Developmental protein, Ribonucleoprotein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 16 "Early spermatids: 215.2;Late spermatids: 560.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 2.2" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041274, HPA061189" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA041274: AB_2677388, HPA061189: AB_2684448" "unprognostic (2.24e-1)" "unprognostic (2.35e-1)" "unprognostic (2.89e-1)" "unprognostic (1.85e-2)" "unprognostic (1.20e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.61e-5)" "unprognostic (4.99e-2)" "unprognostic (2.28e-1)" "unprognostic (5.43e-2)" "unprognostic (4.93e-3)" "unprognostic (4.69e-2)" "unprognostic (3.34e-3)" "unprognostic (6.61e-2)" "unprognostic (2.00e-1)" "unprognostic (4.53e-3)" "unprognostic (1.98e-1)" 19.7 23.9 29.3 21.0 30.1 26.7 19.8 39.5 34.5 27.5 21.6 27.4 23.4 31.2 14.2 31.6 25.7 14.5 37.7 32.3 24.1 19.0 24.4 19.3 23.5 24.2 26.6 37.4 30.4 21.3 24.9 14.9 25.9 22.0 14.3 31.2 23.7 17.4 71.6 34.6 22.8 17.6 23.2 21.7 23.3 51.9 27.1 28.8 20.9 45.3 17.8 26.5 27.3 27.2 44.4 41.6 65.0 62.5 29.0 30.3 55.3 46.0 34.1 93.7 40.9 123.4 30.1 46.5 51.7 31.9 67.9 62.9 31.5 39.6 46.4 19.2 22.9 112.3 57.8 74.3 40.0 48.6 65.1 26.1 70.4 39.1 36.1 36.7 24.3 53.8 61.4 32.7 33.0 58.7 81.2 72.7 40.2 70.8 61.0 104.3 128.5 36.9 25.5 51.7 88.8 77.0 83.9 73.5 61.3 37.5 91.6 60.9 31.8 132.9 90.0 69.1 47.3 40.8 52.1 56.8 58.5 31.7 43.4 0.0 0.4 2.2 0.3 0.3 0.1 0.5 0.2 0.4 0.3 0.5 0.2 0.3 0.6 0.0 0.2 0.4 0.2 0.1 29.3 30.1 39.5 34.5 32.3 24.1 24.2 26.6 25.9 23.2 27.1 27.2 8.6 9.6 6.8 9.1 7.3 9.7 3.5 4.7 5.2 15.1 8.4 7.1 22.8 7.2 7.9 1.8 8.4 6.4 15.3 13.5 1.9 5.0 215.2 13.3 14.1 8.0 13.9 9.5 6.2 5.3 6.0 7.5 8.2 10.3 5.1 14.8 5.0 11.6 8.6 8.4 6.8 12.0 6.1 13.2 6.8 560.0 13.4 8.8 3.6 7.5 8.2 17.2 7.2 5.0 8.4 7.1 8.2 15.8 4.7 9.2 9.7 6.7 12.1 20.3 0.0 9.5 6.4 11.2 23.1 7.6 10.1 5.2 6.9 13.4 12.4 3.0 LSM4 YER112W ENSG00000130520 "LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated" Q9Y4Z0 19 18306236-18323112 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 705.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040932 Uncertain Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "HPA040932: AB_10795529" "unprognostic (2.71e-1)" "unprognostic (1.44e-1)" "unprognostic (1.43e-1)" "unprognostic (7.42e-3)" "unprognostic (1.98e-1)" "unprognostic (4.09e-2)" "unprognostic (1.10e-3)" "unprognostic (9.80e-2)" "unprognostic (1.57e-1)" "prognostic favorable (1.34e-4)" "unprognostic (8.31e-3)" "unprognostic (1.25e-1)" "prognostic favorable (2.22e-4)" "unprognostic (2.51e-2)" "unprognostic (7.23e-2)" "unprognostic (8.08e-2)" "unprognostic (1.34e-1)" 56.5 130.5 97.9 31.8 101.8 62.9 55.1 99.7 111.7 52.7 111.4 86.4 57.6 51.6 36.3 100.5 52.8 17.4 108.2 102.8 104.9 118.8 122.8 60.9 41.4 99.6 102.5 50.6 57.4 48.5 72.5 35.5 105.1 64.2 45.2 33.1 55.2 39.6 149.1 70.4 77.1 27.3 95.9 71.1 78.4 126.8 104.8 78.9 62.2 89.4 38.9 62.1 59.7 97.3 294.3 151.2 252.3 226.2 95.4 91.4 291.8 132.2 113.6 167.9 158.7 137.0 305.5 172.0 274.5 139.0 152.5 192.3 276.4 274.5 127.1 201.1 524.0 156.1 247.0 167.5 94.9 148.9 89.2 83.3 160.5 156.9 182.9 94.2 139.6 248.6 333.0 172.3 177.3 479.7 411.0 321.6 327.1 419.2 475.4 229.4 112.0 320.5 212.9 102.0 283.8 264.9 113.0 141.3 204.2 174.8 140.4 157.8 81.0 98.0 113.2 244.3 250.5 160.2 147.7 204.4 131.4 289.3 170.4 171.5 223.2 163.8 148.3 258.5 182.5 163.5 158.3 154.4 252.8 164.5 169.7 171.4 18.4 220.4 205.6 359.0 166.9 283.9 97.9 101.8 99.7 111.7 102.8 104.9 99.6 102.5 105.1 95.9 104.8 97.3 76.8 28.9 38.8 7.5 85.1 67.4 92.4 183.1 46.7 72.0 141.7 134.9 53.2 74.4 90.5 115.8 14.6 270.4 95.8 179.1 299.3 196.7 280.8 102.8 55.1 75.7 124.4 109.8 11.5 182.1 489.1 67.9 68.8 96.9 117.4 115.7 54.3 89.3 288.4 58.9 11.1 194.5 154.6 85.4 129.0 705.7 62.4 109.1 104.9 7.5 243.2 115.6 130.7 7.1 13.4 159.3 205.5 47.4 98.3 153.1 225.3 347.7 94.6 73.0 46.0 38.5 80.7 203.1 378.6 125.5 71.9 170.5 87.7 174.2 237.1 119.9 LTK TYK1 ENSG00000062524 "Leukocyte receptor tyrosine kinase" P29376 15 41503637-41513887 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.2;lung: 15.1;salivary gland: 11.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 25.3;Gastric mucus-secreting cells: 18.8;Hepatic stellate cells: 11.4;Intestinal goblet cells: 7.9;Proximal enterocytes: 15.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "MAIT T-cell: 5.7;plasmacytoid DC: 5.0" "Group enriched" "Detected in many" 10 "dendritic cells: 5.0;T-cells: 5.7" "Cell line enhanced" "Detected in some" "HEL: 5.0;NB-4: 9.7;RH-30: 4.6;THP-1: 14.7" "Low region specificity" "Detected in many" HPA059545 Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA059545: AB_2684057" "unprognostic (9.47e-4)" "unprognostic (5.52e-4)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (4.12e-1)" "unprognostic (5.65e-3)" "unprognostic (1.74e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.81e-3)" "unprognostic (9.36e-3)" "unprognostic (5.36e-2)" "unprognostic (4.68e-2)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" 0.8 0.6 1.0 1.4 1.6 4.6 0.5 1.2 1.8 0.9 0.6 5.2 12.5 0.2 0.0 0.3 0.4 2.4 1.7 1.3 0.7 4.0 2.9 15.1 1.2 0.6 0.6 0.1 0.3 0.6 0.7 10.4 0.7 0.4 5.7 0.1 11.8 0.3 1.8 1.4 13.2 0.3 0.6 5.5 9.9 2.5 0.8 0.4 0.7 0.0 2.1 0.7 0.7 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.6 0.8 1.2 2.2 0.0 0.0 0.0 0.6 0.0 0.0 2.6 0.0 0.4 0.2 1.3 5.0 0.1 0.0 2.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.0 1.9 0.0 1.8 0.0 0.0 9.7 0.4 1.8 0.2 0.2 4.6 0.1 0.0 0.0 0.4 2.9 0.1 0.2 0.0 2.6 0.2 14.7 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.8 0.0 0.0 0.0 0.4 0.0 5.7 0.5 0.3 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 1.0 1.6 1.2 1.8 1.3 0.7 0.6 0.6 0.7 0.6 0.8 0.9 0.3 0.0 0.0 0.3 1.6 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.8 2.8 0.9 0.0 0.0 0.3 5.5 25.3 0.0 0.0 2.8 0.1 0.4 1.8 1.8 3.2 2.9 0.2 1.5 0.2 18.8 0.2 0.0 0.3 11.4 0.5 0.1 0.0 0.2 7.9 0.0 1.9 0.6 2.1 0.0 0.4 3.6 0.0 0.4 0.0 1.0 0.5 0.4 0.7 5.5 0.0 2.7 0.0 15.3 0.0 5.6 0.0 0.0 0.3 0.5 2.2 1.2 0.0 0.1 0.4 4.0 0.0 3.8 0.0 LY96 MD-2 ENSG00000154589 "Lymphocyte antigen 96" Q9Y6Y9 8 73991392-74029079 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 570.8;Kupffer cells: 544.6;Langerhans cells: 155.4;Macrophages: 198.5;monocytes: 136.0;Plasma cells: 172.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 627.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 627.0" "Cell line enhanced" "Detected in many" "GAMG: 75.1;Karpas-707: 184.9;RPMI-8226: 94.0;U-87 MG: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053060 Approved Vesicles "Secreted to blood" NA NA 250000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA053060: AB_2682029" "unprognostic (2.96e-1)" "unprognostic (2.64e-2)" "unprognostic (2.11e-1)" "unprognostic (1.85e-1)" "unprognostic (1.64e-2)" "unprognostic (2.87e-1)" "unprognostic (2.12e-3)" "unprognostic (1.42e-1)" "unprognostic (8.29e-2)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.38e-11)" "unprognostic (2.87e-2)" "unprognostic (1.29e-2)" "unprognostic (1.60e-2)" "unprognostic (5.90e-2)" 28.6 12.4 12.9 42.4 13.5 17.9 24.7 13.1 22.7 12.9 13.8 15.7 12.3 10.5 5.4 9.0 11.1 35.3 9.5 13.0 14.4 13.2 22.8 22.0 47.4 16.3 14.8 22.6 3.7 2.4 8.0 44.9 14.9 6.1 14.5 1.2 11.4 6.7 3.8 4.4 9.9 20.3 14.7 59.6 10.6 4.7 13.9 16.2 7.3 9.8 39.3 30.5 7.9 17.1 1.5 0.0 0.3 0.2 34.5 73.2 0.1 49.5 61.9 13.5 31.1 0.0 0.5 15.9 16.7 32.6 75.1 0.5 0.2 0.6 34.4 17.1 0.3 0.3 0.0 1.8 17.5 2.7 0.9 21.2 0.4 21.9 4.3 2.2 67.2 9.7 0.2 184.9 48.9 0.0 6.5 2.1 0.2 0.0 1.0 6.4 0.0 94.0 2.5 0.0 0.3 0.2 0.0 0.2 6.5 0.3 0.0 3.3 52.1 33.5 2.6 18.0 12.1 48.1 24.7 9.6 92.3 1.0 14.7 13.7 90.2 0.4 0.5 85.1 1.3 26.3 12.8 1.9 45.8 15.1 8.2 2.9 627.0 0.2 71.8 37.6 21.6 30.6 12.9 13.5 13.1 22.7 13.0 14.4 16.3 14.8 14.9 14.7 13.9 17.1 35.1 16.0 10.7 0.0 48.4 13.8 1.2 1.3 0.0 0.2 11.2 4.4 2.4 0.0 9.7 3.7 0.0 2.7 16.3 0.1 0.0 6.8 24.2 0.3 1.0 63.6 0.0 14.1 2.8 7.4 3.1 32.9 0.0 0.3 3.8 0.0 104.2 3.3 570.8 0.0 3.9 0.0 2.0 544.6 155.4 3.1 14.3 198.5 76.5 21.5 136.0 0.0 1.0 0.5 1.1 9.4 0.0 6.8 172.6 0.8 0.0 1.1 5.6 0.2 6.6 20.0 14.0 0.7 0.2 2.2 11.6 6.4 21.8 12.4 0.3 1.4 LZTS3 "KIAA0552, ProSAPiP1" ENSG00000088899 "Leucine zipper tumor suppressor family member 3" O60299 20 3162617-3173592 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Astrocytes: 17.9;Excitatory neurons: 52.5;Inhibitory neurons: 27.7;Oligodendrocyte precursor cells: 20.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031008, HPA031009" Approved Approved Vesicles NA NA "Cluster 6: Brain - Smell perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA031008: AB_10601610, HPA031009: AB_10670162" "unprognostic (4.09e-2)" "unprognostic (4.10e-2)" "unprognostic (1.55e-2)" "prognostic unfavorable (7.26e-4)" "unprognostic (1.15e-1)" "unprognostic (6.19e-3)" "unprognostic (2.14e-1)" "prognostic favorable (7.98e-4)" "unprognostic (3.31e-1)" "unprognostic (1.08e-1)" "unprognostic (4.57e-2)" "unprognostic (9.69e-3)" "prognostic favorable (5.92e-8)" "unprognostic (4.63e-2)" "unprognostic (1.85e-1)" "unprognostic (8.47e-2)" "unprognostic (1.38e-1)" 4.0 5.9 57.3 1.2 80.0 1.8 5.3 57.7 77.9 14.5 1.6 5.9 9.8 7.6 3.6 3.0 10.0 7.5 12.2 67.2 21.5 27.8 7.1 9.5 1.0 25.6 21.1 16.1 30.7 9.5 15.1 2.0 27.2 11.2 2.0 54.0 43.4 7.9 11.8 4.0 9.8 2.6 11.8 2.4 21.1 6.1 23.8 1.4 18.5 4.5 0.7 7.6 6.0 55.5 3.5 3.3 4.6 5.2 6.3 1.8 3.2 3.5 7.5 5.8 8.5 19.2 9.9 6.0 1.9 6.9 7.5 1.7 2.6 3.7 4.4 0.1 3.3 0.2 0.7 15.9 14.2 0.3 1.6 2.3 8.1 8.1 3.1 2.1 0.9 5.5 3.5 1.9 2.8 1.6 0.5 0.7 10.4 8.2 3.2 1.6 1.5 6.6 7.4 1.3 18.1 5.6 2.9 4.0 2.8 6.7 9.5 0.2 5.4 6.2 11.7 2.5 1.1 3.7 0.6 1.8 3.0 1.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.3 80.0 57.7 77.9 67.2 21.5 25.6 21.1 27.2 11.8 23.8 55.5 2.6 19.2 10.3 17.9 1.3 1.5 0.0 3.3 0.0 0.0 7.4 6.3 16.6 0.0 12.9 11.0 0.0 1.6 0.4 0.9 11.7 4.9 0.0 9.7 5.7 1.6 1.8 0.0 52.5 5.1 0.4 3.7 0.0 11.9 0.0 2.2 0.0 0.0 0.3 0.0 27.7 0.0 6.1 0.0 1.1 0.0 0.0 0.5 3.6 3.7 0.0 0.0 0.0 20.6 7.1 8.2 0.0 0.0 0.3 0.0 0.0 11.2 11.3 0.0 0.0 0.0 3.0 0.0 0.0 0.0 1.0 1.6 0.5 1.5 0.6 0.0 MAN1B1 "ERManI, MANA-ER, MRT15" ENSG00000177239 "Mannosidase alpha class 1B member 1" Q9UKM7 9 137086985-137109183 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051516 Approved Uncertain Vesicles NA NA 940000 "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA051516: AB_2681518" "unprognostic (1.21e-2)" "unprognostic (4.66e-1)" "unprognostic (1.25e-3)" "unprognostic (4.67e-3)" "unprognostic (2.27e-1)" "unprognostic (3.70e-3)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.59e-1)" "unprognostic (6.67e-2)" "unprognostic (1.79e-2)" "unprognostic (5.93e-3)" "unprognostic (1.75e-1)" "unprognostic (3.55e-2)" "unprognostic (2.28e-1)" "unprognostic (5.85e-2)" "unprognostic (2.37e-1)" "unprognostic (1.44e-3)" 25.3 32.2 21.3 12.1 21.2 9.1 25.1 21.1 32.9 22.6 26.3 24.1 15.5 20.7 20.4 32.1 22.0 20.1 27.3 22.4 23.1 31.8 39.6 23.0 15.4 22.6 22.7 28.0 36.0 20.0 32.6 21.4 25.2 26.1 9.9 3.6 34.2 15.2 17.6 32.6 22.9 12.1 21.7 28.7 25.6 28.3 22.9 13.8 27.1 9.9 10.1 22.0 21.9 22.8 22.8 50.7 18.2 49.9 67.0 57.7 57.0 37.9 78.4 48.6 43.7 24.9 67.4 20.0 118.8 64.7 69.2 74.3 11.0 36.3 9.1 27.7 17.3 8.7 41.2 33.2 59.6 16.0 33.1 65.1 66.9 29.1 25.1 67.1 32.4 26.5 24.5 32.7 36.4 45.0 16.7 37.8 23.5 67.3 50.0 9.7 30.6 63.9 41.6 11.3 20.4 18.3 55.2 55.9 38.7 9.6 63.5 31.5 46.5 69.6 25.9 52.9 43.6 13.0 11.1 13.3 84.6 19.9 61.6 17.9 31.2 27.0 32.4 34.4 30.2 19.1 25.1 30.4 36.0 16.4 24.3 25.0 9.0 31.0 42.2 26.6 34.5 32.1 21.3 21.2 21.1 32.9 22.4 23.1 22.6 22.7 25.2 21.7 22.9 22.8 18.8 19.2 27.3 23.5 18.3 11.6 12.6 33.0 12.0 20.7 23.5 21.7 10.3 14.3 21.5 25.8 16.7 53.2 24.3 39.1 7.9 32.0 5.8 21.5 16.4 19.7 30.5 14.3 13.0 32.0 72.4 26.9 23.4 20.3 21.0 47.8 25.0 25.2 32.1 30.3 10.2 28.1 22.4 22.9 17.4 6.8 21.1 21.8 23.2 11.2 29.3 16.0 16.5 6.6 12.8 27.6 25.0 21.8 25.4 9.0 35.9 15.9 24.9 19.3 13.1 19.4 20.2 16.1 28.4 16.3 16.2 45.4 21.5 41.1 25.6 8.2 MANBA ENSG00000109323 "Mannosidase beta" O00462 4 102630770-102760994 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Macrophages: 74.0;Microglial cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.6" "Group enriched" "Detected in many" 5 "dendritic cells: 5.3;granulocytes: 16.6;monocytes: 9.1" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;hTCEpi: 13.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053478 Approved Supported Vesicles NA NA 15000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 57: B-cells - Immune response" Vesicles "HPA053478: AB_2682165" "unprognostic (2.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.80e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (4.11e-2)" "prognostic unfavorable (3.74e-6)" "unprognostic (1.32e-1)" "unprognostic (2.19e-1)" "unprognostic (4.87e-2)" "unprognostic (7.78e-2)" "unprognostic (1.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (7.12e-2)" "unprognostic (4.81e-2)" "unprognostic (2.13e-1)" 7.1 12.4 1.9 1.5 2.4 7.0 6.4 4.7 2.2 6.5 2.2 6.7 1.6 6.1 0.2 3.8 6.3 1.3 6.6 1.1 2.1 4.8 4.7 10.5 2.1 3.8 2.9 8.8 8.3 3.0 5.0 3.7 4.7 4.3 1.1 2.7 8.9 2.0 3.0 4.5 8.5 2.4 3.0 12.0 9.1 1.6 3.5 1.2 7.1 0.1 2.0 8.1 5.8 3.7 2.9 1.4 0.6 1.6 15.5 12.1 0.9 1.1 6.9 1.8 4.1 1.7 1.0 3.6 1.4 2.7 3.9 1.0 3.0 2.2 1.1 2.2 0.7 3.0 1.1 0.7 2.7 2.8 8.2 3.7 13.7 7.6 3.4 8.9 3.0 1.2 3.6 2.0 3.4 1.4 2.0 2.3 1.3 1.9 1.1 1.9 1.6 0.6 3.4 2.3 1.4 0.5 1.4 1.9 1.5 5.4 4.5 1.8 0.2 2.0 1.3 9.3 1.2 1.3 5.8 0.5 3.1 1.5 1.6 4.0 6.8 16.6 0.4 6.1 0.7 1.7 0.0 0.7 5.3 2.1 0.4 0.6 6.1 1.8 9.1 1.2 0.5 3.1 1.9 2.4 4.7 2.2 1.1 2.1 3.8 2.9 4.7 3.0 3.5 3.7 6.4 32.1 35.6 24.5 45.4 5.9 8.4 13.2 12.0 6.2 11.6 8.1 14.6 14.3 13.5 9.2 6.2 42.3 14.3 5.1 1.9 8.1 2.8 6.9 6.9 8.1 1.8 19.7 36.4 2.7 7.3 13.8 25.5 12.8 34.8 5.5 10.4 17.7 43.6 6.7 66.5 10.5 2.0 58.5 29.6 1.6 9.0 74.0 0.0 111.5 52.8 5.2 17.5 31.2 66.8 5.5 17.3 19.9 17.5 7.5 5.2 9.8 5.8 7.5 0.0 10.8 6.7 0.2 1.4 12.6 4.5 22.6 16.9 12.6 11.2 9.7 MAP1LC3A "ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3" ENSG00000101460 "Microtubule associated protein 1 light chain 3 alpha" Q9H492 20 34546854-34560345 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 674.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 85.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 85.4" "Cell line enhanced" "Detected in many" "HHSteC: 57.5;HSkMC: 71.2;SK-BR-3: 62.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007649, CAB037174, HPA042824, HPA052474, HPA052484" Enhanced Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB037174: AB_1079382, HPA007649: AB_1853943, HPA042824: , HPA052474: AB_2681844, HPA052484: AB_2681846" "unprognostic (6.10e-3)" "unprognostic (8.03e-2)" "unprognostic (1.02e-1)" "unprognostic (1.99e-2)" "unprognostic (4.56e-3)" "unprognostic (1.06e-2)" "unprognostic (1.55e-1)" "unprognostic (1.79e-1)" "unprognostic (4.78e-2)" "unprognostic (1.98e-1)" "prognostic favorable (5.31e-5)" "unprognostic (2.82e-2)" "unprognostic (1.59e-3)" "unprognostic (3.84e-1)" "unprognostic (1.35e-1)" "unprognostic (7.90e-2)" "unprognostic (2.76e-1)" 53.0 26.6 120.8 13.7 122.1 16.4 40.6 114.4 177.2 49.6 69.7 56.3 30.6 44.9 17.8 22.6 41.7 23.9 81.7 123.7 148.4 54.2 53.2 39.4 28.1 137.1 135.6 38.3 24.8 23.7 84.8 12.4 155.9 46.6 19.7 31.6 31.0 20.3 54.7 64.8 44.9 19.1 101.2 22.0 36.6 52.8 116.2 6.9 52.9 34.1 30.4 39.1 43.5 123.3 0.0 7.0 4.2 0.0 28.4 37.3 0.2 26.1 21.9 16.3 14.9 0.1 0.5 0.0 0.3 21.3 39.5 4.8 0.1 8.1 3.2 6.2 2.0 0.1 17.2 0.0 57.5 0.0 14.0 71.2 1.4 11.4 4.9 0.1 13.5 0.0 0.0 0.1 17.4 0.0 0.2 0.5 1.6 5.3 5.2 0.0 0.0 0.0 0.0 0.0 41.4 31.9 29.6 62.2 0.0 16.3 0.3 22.7 20.5 45.2 0.4 9.8 11.2 0.0 6.5 0.0 29.4 0.0 16.1 4.0 3.2 11.0 5.1 4.8 3.7 9.4 5.5 5.4 1.0 6.0 1.7 3.4 85.4 3.3 1.7 4.5 12.1 2.9 120.8 122.1 114.4 177.2 123.7 148.4 137.1 135.6 155.9 101.2 116.2 123.3 107.4 0.0 6.6 19.2 18.3 57.7 123.0 50.5 12.5 127.2 41.9 57.8 25.4 41.5 27.1 46.0 85.5 25.7 26.1 67.3 113.5 42.0 137.3 98.4 78.4 64.4 165.1 3.6 48.4 23.5 15.8 75.4 34.1 90.6 18.4 90.8 75.7 44.6 37.9 70.7 58.8 70.5 136.3 16.1 47.1 674.0 95.1 17.5 62.2 14.0 21.0 98.7 7.2 12.5 54.6 44.7 82.5 108.7 10.1 146.3 149.4 120.0 40.7 127.7 138.1 77.7 119.3 53.0 21.6 5.8 51.4 211.8 26.4 79.8 76.7 98.1 MAP3K15 "ASK3, bA723P2.3, FLJ16518" ENSG00000180815 "Mitogen-activated protein kinase kinase kinase 15" Q6ZN16 X 19360056-19515261 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 10.8;choroid plexus: 13.1" "Cell type enhanced" "Detected in some" "Collecting duct cells: 5.5;Cone photoreceptor cells: 4.2;Granulosa cells: 7.5;Theca cells: 29.8" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.0;HAP1: 4.9;HEK 293: 4.1;JURKAT: 2.5;REH: 2.6;SuSa: 4.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA004006 Approved Vesicles NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA004006: AB_1079358" "unprognostic (2.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.21e-2)" "unprognostic (6.56e-8)" "unprognostic (3.47e-2)" "unprognostic (1.42e-2)" "unprognostic (2.19e-3)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (4.87e-2)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (2.77e-3)" "unprognostic (4.00e-1)" "unprognostic (2.37e-1)" "unprognostic (3.98e-2)" "unprognostic (8.20e-2)" 0.0 10.8 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.6 1.1 0.0 0.3 0.0 0.0 0.3 0.4 0.5 0.7 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.3 0.0 4.9 0.0 0.0 0.8 4.1 1.7 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.1 0.0 1.1 1.3 0.0 0.5 2.6 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.6 0.0 0.3 0.4 0.0 0.2 0.0 0.2 0.0 3.1 0.3 0.0 0.1 0.5 0.0 0.0 1.0 0.2 0.6 2.9 0.0 0.0 5.5 4.2 0.0 0.1 0.2 3.9 0.0 0.4 0.3 0.3 0.1 0.0 0.4 2.6 0.0 0.3 0.4 0.0 0.3 0.0 7.5 0.4 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 1.0 0.0 0.3 0.0 0.5 1.1 0.1 0.0 1.2 0.0 0.2 0.0 0.1 0.0 0.6 0.0 0.3 0.2 0.6 1.4 0.0 0.0 0.1 0.2 29.8 0.1 0.0 MAP4K2 "BL44, GCK, RAB8IP" ENSG00000168067 "Mitogen-activated protein kinase kinase kinase kinase 2" Q12851 11 64784918-64803241 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007330 Enhanced Approved Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" Vesicles "HPA007330: AB_1079361" "unprognostic (1.66e-1)" "unprognostic (2.83e-1)" "unprognostic (3.07e-3)" "unprognostic (4.37e-3)" "unprognostic (2.67e-1)" "unprognostic (9.23e-2)" "prognostic unfavorable (3.10e-5)" "unprognostic (4.51e-2)" "unprognostic (3.65e-1)" "unprognostic (5.28e-2)" "unprognostic (1.24e-2)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.57e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" 5.0 3.9 8.9 6.9 7.2 15.5 4.1 9.8 9.9 4.6 4.9 5.6 3.3 4.8 2.5 2.7 3.8 4.2 4.3 7.6 7.0 5.4 2.0 9.7 17.6 7.8 8.0 3.4 5.0 3.2 5.8 8.9 8.1 4.7 3.0 5.3 6.6 5.8 2.5 3.5 8.9 3.7 6.6 18.0 5.2 4.6 9.7 7.4 7.0 1.5 14.2 4.6 3.5 8.8 9.4 8.4 5.4 9.8 4.7 2.9 12.7 7.0 6.5 8.2 5.8 3.7 4.3 16.4 12.6 8.0 14.5 2.8 6.5 6.8 4.9 21.5 3.1 28.9 12.0 7.9 5.8 15.3 10.4 2.9 3.4 6.4 4.1 5.7 20.3 28.0 2.5 1.5 2.5 11.8 9.2 15.2 3.6 5.6 11.2 18.8 0.6 18.9 4.6 4.7 6.4 9.3 6.0 7.8 6.4 6.1 15.5 23.2 15.8 6.8 15.0 6.3 2.9 1.8 3.8 18.1 6.0 22.8 5.1 2.2 4.3 5.9 4.9 12.5 4.9 9.9 6.5 4.4 4.4 6.6 7.7 6.0 8.0 2.5 15.8 5.0 9.5 7.3 8.9 7.2 9.8 9.9 7.6 7.0 7.8 8.0 8.1 6.6 9.7 8.8 21.6 3.2 4.8 6.8 32.9 1.3 2.8 1.8 6.2 20.6 8.1 10.4 4.7 7.2 2.4 1.8 25.0 7.6 9.4 6.8 3.9 1.7 33.8 2.6 3.8 20.0 6.0 5.0 5.9 1.7 11.3 4.9 9.2 6.0 1.3 7.7 24.3 2.0 11.0 11.8 4.6 1.8 6.1 8.9 3.1 46.8 4.1 16.2 1.8 18.7 13.4 7.2 14.4 2.0 7.2 0.9 16.2 7.2 15.6 1.8 1.6 3.6 1.5 14.6 6.6 3.7 4.3 2.1 13.8 5.2 1.4 5.1 19.9 22.6 2.2 2.0 MAPK8IP3 "JIP3, JSAP1, KIAA1066, syd" ENSG00000138834 "Mitogen-activated protein kinase 8 interacting protein 3" Q9UPT6 16 1706183-1770351 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 62.1;Horizontal cells: 87.5;Inhibitory neurons: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005580, HPA041785, HPA069311" Approved Approved Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 57: B-cells - Immune response" Vesicles "CAB005580: AB_627840, HPA041785: AB_2677671, HPA069311: AB_2686116" "unprognostic (1.49e-1)" "unprognostic (2.22e-1)" "unprognostic (8.28e-3)" "unprognostic (8.32e-2)" "unprognostic (3.90e-1)" "unprognostic (6.83e-3)" "unprognostic (3.66e-2)" "unprognostic (2.41e-2)" "unprognostic (1.55e-1)" "unprognostic (8.67e-2)" "unprognostic (1.57e-2)" "unprognostic (6.91e-3)" "prognostic unfavorable (5.25e-5)" "unprognostic (2.84e-1)" "unprognostic (1.85e-1)" "unprognostic (2.45e-1)" "prognostic favorable (3.95e-4)" 25.1 32.2 29.3 13.5 36.5 26.4 26.1 16.2 64.9 38.6 0.0 26.9 13.5 25.9 4.0 20.2 31.7 7.9 39.3 39.7 18.5 34.1 30.8 31.7 16.3 39.5 17.4 46.8 39.3 7.0 78.6 8.5 34.9 43.6 3.8 11.3 28.8 7.4 22.1 37.0 39.4 4.4 7.9 49.8 25.9 32.0 18.4 11.8 38.3 4.3 6.5 35.2 30.5 44.9 6.5 12.2 12.7 11.4 6.1 10.3 9.9 10.7 4.0 5.2 4.6 17.3 21.0 7.5 6.6 6.7 3.7 12.1 3.1 7.0 1.7 11.9 14.1 10.0 33.6 13.4 8.4 6.5 16.9 20.7 9.2 7.6 3.7 22.9 6.9 14.1 8.6 14.1 5.5 16.6 10.2 28.5 8.5 3.2 6.9 44.1 6.3 12.9 6.4 8.4 26.4 21.0 12.8 11.8 5.3 5.8 6.4 9.1 21.9 21.8 12.2 9.4 8.6 31.4 5.8 9.7 5.7 6.7 11.1 0.0 0.2 0.5 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.1 29.3 36.5 16.2 64.9 39.7 18.5 39.5 17.4 34.9 7.9 18.4 44.9 9.1 3.2 7.8 46.7 30.5 9.8 4.3 10.0 13.1 40.8 7.9 7.5 6.6 10.0 10.5 3.7 37.5 5.6 10.4 16.8 1.9 4.9 24.9 13.2 13.0 7.8 10.2 8.6 62.1 3.8 5.7 7.5 34.7 21.9 1.3 23.4 6.4 9.7 7.2 87.5 65.2 11.1 10.2 10.3 12.5 23.4 7.8 13.5 7.2 31.9 8.7 11.9 9.2 32.6 52.8 7.7 9.5 9.1 17.6 4.7 10.3 1.2 15.9 19.2 6.6 7.3 8.2 19.8 5.1 10.8 9.7 5.6 11.8 5.9 11.7 6.0 MARCHF3 "MARCH-III, MARCH3, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030558 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 43.8;Syncytiotrophoblasts: 98.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.5;naive B-cell: 12.1" "Lineage enriched" "Detected in many" 4 "B-cells: 12.1" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 40.4;HUVEC TERT2: 27.4;TIME: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043406 Uncertain Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA043406: AB_10793947" "unprognostic (5.96e-3)" "unprognostic (1.46e-2)" "unprognostic (1.91e-2)" "unprognostic (4.21e-2)" "unprognostic (9.00e-3)" "unprognostic (1.17e-2)" "unprognostic (7.75e-3)" "unprognostic (9.41e-2)" "unprognostic (8.93e-2)" "unprognostic (2.05e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (5.60e-6)" "unprognostic (7.74e-2)" "unprognostic (7.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.64e-1)" 5.6 2.8 6.1 2.9 5.6 3.7 2.6 5.3 4.1 0.9 1.9 5.3 0.9 1.4 0.0 1.4 1.5 5.2 7.8 3.9 5.7 0.8 0.7 2.4 2.5 11.5 7.1 1.1 2.4 0.3 2.4 1.7 7.9 0.6 5.6 7.4 4.6 0.2 6.5 5.8 2.4 2.9 8.3 1.6 2.4 5.6 7.8 1.3 1.4 3.3 2.1 7.6 0.7 8.5 0.4 1.8 3.9 2.1 3.4 3.2 1.2 14.2 5.9 11.1 16.3 1.9 0.8 3.8 1.3 1.9 2.4 1.1 4.9 2.5 15.3 0.8 4.7 12.2 3.2 1.9 5.6 5.0 3.0 2.4 0.7 40.4 4.8 2.6 27.4 0.6 5.1 0.7 9.3 1.3 0.5 2.3 3.3 3.0 4.6 1.5 15.5 1.2 0.9 2.0 1.3 0.9 3.3 0.5 1.6 1.9 2.9 5.0 33.5 2.2 1.8 12.6 1.6 1.9 2.3 2.3 8.3 3.8 2.0 0.0 0.2 2.8 0.5 0.4 0.1 10.5 0.6 0.3 0.1 12.1 2.3 0.5 0.8 2.3 0.3 0.7 2.9 0.8 6.1 5.6 5.3 4.1 3.9 5.7 11.5 7.1 7.9 8.3 7.8 8.5 3.8 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 43.8 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.2 5.8 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 98.6 0.6 0.0 0.0 0.0 MBOAT2 "FLJ14415, FLJ90298, OACT2" ENSG00000143797 "Membrane bound O-acyltransferase domain containing 2" Q6ZWT7 2 8852690-9003709 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 171.1;Erythroid cells: 162.6;Excitatory neurons: 134.6;Horizontal cells: 141.3;Oligodendrocyte precursor cells: 177.4;Oligodendrocytes: 230.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 4.7;eosinophil: 1.7;neutrophil: 4.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 4.7" "Cell line enhanced" "Detected in many" "SK-BR-3: 41.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014836 Uncertain Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA014836: AB_1854745" "unprognostic (2.49e-1)" "unprognostic (2.17e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (2.13e-9)" "unprognostic (1.30e-1)" "unprognostic (2.32e-2)" "unprognostic (2.38e-1)" "unprognostic (3.97e-3)" "unprognostic (3.09e-1)" "unprognostic (3.00e-1)" "unprognostic (1.03e-3)" "unprognostic (1.70e-1)" "unprognostic (5.90e-2)" "unprognostic (2.23e-1)" "unprognostic (3.04e-2)" "unprognostic (6.66e-2)" "prognostic unfavorable (5.32e-4)" 2.2 2.1 16.4 2.4 23.6 26.9 9.0 20.5 18.4 7.7 26.2 7.6 2.4 4.6 2.7 15.8 2.9 3.6 4.6 18.9 21.9 7.0 0.8 6.7 1.9 21.8 22.2 5.8 1.4 29.3 5.4 3.2 22.4 14.4 8.5 15.6 5.7 2.3 1.1 11.6 3.7 3.9 20.6 2.4 6.1 2.1 21.9 2.4 4.5 1.1 4.8 3.8 8.4 29.3 14.0 4.2 12.7 5.4 5.6 12.5 7.3 6.5 2.4 8.5 5.6 1.1 21.9 3.9 7.5 15.9 6.8 10.5 11.4 13.5 12.6 12.3 19.0 16.7 5.9 0.0 6.9 0.0 5.0 9.1 7.8 8.1 5.6 18.5 4.5 5.5 14.4 3.0 7.5 3.6 4.9 0.3 5.0 6.4 15.8 7.4 20.0 0.1 12.6 2.0 7.6 23.0 6.9 41.1 6.6 6.2 7.7 4.8 2.5 14.7 7.7 11.6 19.0 1.1 0.4 4.3 23.3 2.4 5.1 4.7 0.4 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 4.0 0.0 0.1 0.1 0.0 0.2 16.4 23.6 20.5 18.4 18.9 21.9 21.8 22.2 22.4 20.6 21.9 29.3 7.7 19.2 12.7 171.1 1.7 3.3 4.6 33.1 0.6 20.6 18.1 12.1 12.2 7.2 54.7 40.5 8.4 3.9 1.1 28.2 5.9 5.6 9.7 3.2 19.4 13.4 37.6 162.6 134.6 1.5 1.4 12.7 21.4 2.9 8.2 14.7 4.6 0.2 1.8 141.3 107.8 59.3 32.6 1.9 17.7 12.7 5.3 5.0 14.2 33.7 29.0 98.7 0.0 177.4 230.5 88.1 42.9 7.5 0.3 19.5 1.6 10.4 45.7 8.8 6.6 10.5 15.2 12.1 24.8 24.4 5.1 1.9 2.0 1.9 12.7 66.4 MDK "FLJ27379, MK, NEGF2" ENSG00000110492 Midkine P21741 11 46380756-46383837 "Cancer-related genes, Predicted secreted proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 529.1" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 1010.4;Granulosa cells: 726.2;Paneth cells: 1272.7;Proximal enterocytes: 883.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.8;neutrophil: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NTERA-2: 888.4;REH: 1343.8;SH-SY5Y: 1093.6" "CAB010055, HPA057126" Uncertain Approved Vesicles "Secreted to blood" NA NA 158000 960000 "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB010055: AB_627949, HPA057126: AB_2683344" "unprognostic (8.87e-3)" "unprognostic (6.65e-2)" "unprognostic (4.02e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (1.90e-1)" "unprognostic (5.67e-3)" "unprognostic (1.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.11e-2)" "unprognostic (4.01e-2)" "unprognostic (4.15e-1)" "prognostic unfavorable (3.06e-6)" "unprognostic (8.78e-2)" "unprognostic (1.31e-1)" "unprognostic (3.48e-1)" "unprognostic (1.12e-2)" 41.1 98.0 23.3 22.9 23.3 11.7 82.2 27.0 37.0 379.4 16.3 78.0 263.3 208.2 60.3 38.1 170.3 140.0 36.1 21.6 40.7 35.9 8.5 48.5 20.3 31.8 27.5 529.1 30.5 103.9 370.4 32.0 22.6 128.7 38.0 5.9 137.4 84.1 7.6 26.9 211.3 49.5 24.6 78.1 108.3 16.8 31.5 92.9 26.8 9.8 15.9 84.1 129.3 24.6 51.1 66.5 758.4 2.5 5.2 62.2 18.6 39.2 77.0 145.6 128.8 505.2 219.5 3.4 528.6 58.5 6.3 429.6 431.8 0.7 13.3 157.0 91.6 22.5 5.6 703.6 336.2 1.7 3.5 100.0 13.2 89.2 0.5 31.0 214.3 28.9 385.2 3.5 83.3 348.6 19.8 9.4 888.4 275.9 388.0 1343.8 28.8 4.4 1.8 1.6 418.1 1093.6 128.9 11.3 11.0 665.8 347.3 349.5 59.0 221.1 526.2 3.1 27.2 2.9 11.0 5.1 6.5 13.7 197.3 0.0 0.0 0.0 0.1 0.2 0.0 1.8 0.1 0.2 0.0 0.4 0.0 0.0 2.1 0.1 0.2 0.1 0.9 0.4 23.3 23.3 27.0 37.0 21.6 40.7 31.8 27.5 22.6 24.6 31.5 24.6 108.2 0.0 5.4 5.5 9.6 11.1 162.1 392.4 12.5 1.3 245.2 218.7 7.0 34.3 393.6 47.8 0.0 162.3 5.4 499.0 1.9 286.0 26.4 134.6 490.2 115.0 1010.4 2.5 2.1 104.5 123.5 275.2 162.1 228.2 4.5 726.2 102.4 4.6 48.3 0.0 1.9 368.8 286.8 4.2 12.0 126.3 109.6 10.0 37.4 7.5 9.4 47.1 0.0 4.5 1.3 221.1 1272.7 18.8 18.6 163.6 883.4 19.6 109.5 1.1 85.5 26.1 197.0 31.8 34.3 26.2 8.1 153.1 11.4 8.9 187.6 511.1 MEMO1 "C2orf4, CGI-27, MEMO" ENSG00000162959 "Mediator of cell motility 1" Q9Y316 2 31865060-32011230 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 115.0;Inhibitory neurons: 111.2;Microglial cells: 100.2;Oligodendrocyte precursor cells: 106.1;Oligodendrocytes: 134.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042603, HPA057952" Approved Approved Vesicles NA NA 9100 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 24: NB-4 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA042603: AB_10806243, HPA057952: AB_2683562" "unprognostic (1.33e-1)" "unprognostic (1.28e-3)" "unprognostic (1.81e-1)" "unprognostic (2.94e-5)" "unprognostic (1.02e-2)" "unprognostic (3.96e-2)" "unprognostic (2.24e-4)" "unprognostic (1.70e-2)" "unprognostic (6.73e-2)" "unprognostic (8.37e-3)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (5.95e-9)" "unprognostic (6.57e-2)" "unprognostic (2.26e-1)" "unprognostic (3.77e-2)" "unprognostic (4.23e-2)" 17.2 23.7 15.0 23.2 13.7 45.7 14.7 14.0 14.1 15.1 9.9 17.5 16.7 14.4 16.7 33.6 13.1 13.4 36.3 13.4 13.7 16.4 35.9 13.9 31.9 14.2 14.2 10.7 17.3 14.6 11.9 20.6 13.9 14.2 20.7 11.7 16.8 13.6 58.8 19.2 16.7 19.5 13.4 20.3 17.3 62.2 14.4 31.5 12.5 36.5 34.2 26.3 19.3 16.8 87.7 37.4 40.5 37.8 34.8 49.4 73.0 73.6 45.7 41.1 31.5 51.0 48.2 92.4 23.2 50.6 54.2 43.4 48.4 63.9 54.0 61.8 26.4 67.0 22.8 62.7 48.6 67.7 53.7 37.2 40.7 40.6 40.7 46.7 65.1 21.8 49.0 41.4 72.2 38.3 81.5 137.8 60.0 74.9 46.2 54.4 46.0 71.4 81.8 83.6 34.2 63.3 38.0 90.7 59.2 33.9 38.2 80.4 61.0 57.0 63.4 45.8 82.1 42.8 69.8 79.7 51.7 96.1 45.7 1.8 16.6 17.1 7.5 23.4 5.7 9.6 9.2 9.0 24.4 7.5 6.6 6.5 13.4 12.6 27.9 9.1 17.1 10.1 15.0 13.7 14.0 14.1 13.4 13.7 14.2 14.2 13.9 13.4 14.4 16.8 6.7 6.4 13.3 70.8 19.1 27.8 17.2 10.3 17.6 15.3 10.6 6.3 4.7 12.8 9.3 11.0 16.7 13.3 9.0 8.3 1.9 4.9 3.6 5.2 9.1 11.3 13.1 18.3 115.0 2.6 10.5 9.6 11.2 8.7 10.1 10.2 14.3 14.0 10.1 11.8 111.2 7.0 8.2 19.2 18.4 3.0 13.1 15.2 12.4 100.2 21.8 4.6 14.4 106.1 134.4 7.5 8.3 8.6 11.2 19.7 8.5 2.4 8.8 10.5 6.6 12.5 6.0 12.2 6.4 26.9 16.6 16.6 12.8 7.9 10.4 16.8 METAP1D "MAP1D, Metap1l" ENSG00000172878 "Methionyl aminopeptidase type 1D, mitochondrial" Q6UB28 2 171999943-172082430 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 39.5;Oligodendrocyte precursor cells: 35.7;Oligodendrocytes: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030298, HPA030299, HPA077742" Uncertain Uncertain Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA030298: AB_2673419, HPA030299: AB_10602421, HPA077742: " "unprognostic (5.31e-2)" "unprognostic (1.07e-1)" "unprognostic (1.88e-1)" "unprognostic (5.83e-2)" "unprognostic (2.54e-2)" "unprognostic (7.90e-3)" "unprognostic (1.92e-3)" "unprognostic (1.07e-2)" "unprognostic (4.55e-1)" "unprognostic (7.07e-2)" "unprognostic (2.64e-2)" "unprognostic (8.19e-2)" "unprognostic (2.53e-3)" "unprognostic (3.44e-3)" "unprognostic (3.06e-2)" "unprognostic (5.48e-3)" "unprognostic (2.92e-2)" 4.4 4.9 4.3 2.4 4.5 3.5 3.9 3.7 5.0 5.4 3.7 4.6 2.3 4.5 2.8 3.4 6.7 2.0 4.8 4.1 5.1 4.5 6.0 2.3 2.8 4.1 4.1 11.9 8.1 2.2 4.3 1.8 4.6 5.6 3.2 2.5 4.1 3.7 7.8 3.4 4.1 2.8 3.6 5.8 4.6 2.8 4.3 1.2 3.6 5.6 2.0 4.2 3.8 5.0 3.6 2.8 4.1 13.5 5.9 7.7 8.3 4.1 4.1 6.4 4.1 6.4 4.7 1.8 7.2 4.3 6.6 6.4 9.1 7.2 6.5 6.3 10.6 10.2 7.8 8.6 6.2 6.1 2.6 5.8 10.9 6.4 10.2 5.5 3.6 6.9 14.8 5.1 4.9 4.4 3.5 8.2 7.4 10.4 3.4 7.7 3.5 3.3 4.5 5.0 8.4 3.2 2.9 5.8 10.2 3.6 6.7 8.1 4.4 8.1 6.4 5.0 4.0 6.3 6.1 4.0 5.8 11.9 7.9 0.0 0.0 0.0 0.4 0.4 0.2 0.3 0.5 0.2 0.1 0.7 0.5 1.1 0.0 0.4 0.0 0.0 0.4 0.2 4.3 4.5 3.7 5.0 4.1 5.1 4.1 4.1 4.6 3.6 4.3 5.0 6.1 0.0 4.6 23.8 15.4 5.6 10.3 7.5 22.8 5.8 9.2 8.9 4.5 7.2 3.5 3.7 2.1 4.1 2.7 1.3 7.9 2.5 1.2 2.7 14.7 5.4 0.0 16.8 19.6 3.5 4.7 10.9 8.2 2.5 4.5 17.9 6.4 6.4 3.9 5.0 39.5 2.9 2.0 2.5 2.2 2.3 33.5 2.2 5.4 14.0 1.0 3.7 9.2 35.7 35.5 1.4 1.3 26.4 9.9 4.3 0.6 5.7 2.0 6.1 13.1 18.1 9.5 9.8 12.2 11.6 5.7 1.9 7.5 14.5 5.7 5.1 METTL23 "C17orf95, LOC124512" ENSG00000181038 "Methyltransferase like 23" Q86XA0 17 76726830-76733936 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 182.5;Spermatocytes: 198.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022889 Approved Vesicles No No "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA022889: " "unprognostic (5.45e-3)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" "unprognostic (1.35e-1)" "unprognostic (7.70e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (4.18e-6)" "unprognostic (5.22e-2)" "unprognostic (1.76e-1)" "unprognostic (1.73e-2)" "unprognostic (1.03e-3)" "unprognostic (3.21e-2)" "prognostic unfavorable (3.93e-7)" "unprognostic (1.13e-2)" "unprognostic (1.82e-1)" "unprognostic (3.79e-1)" "unprognostic (3.65e-1)" 30.8 32.7 20.4 24.2 22.8 27.3 30.6 22.5 27.9 28.7 24.2 26.0 22.6 25.8 34.7 23.9 27.7 19.8 28.5 20.1 21.4 39.1 47.3 26.7 42.7 21.9 22.0 29.4 42.2 35.1 33.3 19.7 22.7 28.1 27.4 22.9 29.1 21.9 34.7 29.2 30.7 23.5 22.3 48.1 30.0 51.6 21.9 36.9 42.1 25.9 40.4 26.1 24.7 26.1 68.3 58.4 32.6 30.0 79.2 66.5 31.3 33.7 68.2 43.5 41.9 29.5 47.1 38.0 32.2 43.0 56.7 37.6 23.8 61.0 48.9 19.2 55.8 49.5 38.0 56.6 77.4 35.1 41.7 64.0 57.3 54.0 74.6 68.5 69.1 46.5 48.1 46.0 53.1 38.5 44.3 30.1 24.2 75.2 65.3 29.9 54.5 106.5 63.0 33.9 30.9 44.5 33.8 51.6 123.3 78.8 72.3 43.7 25.8 49.8 24.9 48.9 59.9 63.2 26.0 38.6 47.5 25.0 46.3 23.0 28.9 34.1 48.0 30.3 53.6 51.3 53.0 53.5 32.1 44.7 50.2 51.1 9.4 51.8 27.9 48.3 57.6 34.5 20.4 22.8 22.5 27.9 20.1 21.4 21.9 22.0 22.7 22.3 21.9 26.1 39.5 28.9 14.5 8.5 49.6 16.4 47.2 64.8 42.1 13.9 34.9 48.4 17.7 27.1 35.6 20.2 10.4 42.9 50.7 11.7 119.3 42.0 182.5 31.7 23.4 28.0 22.8 22.3 4.2 39.5 41.1 26.6 24.5 25.9 31.1 21.8 25.7 49.9 57.0 6.7 5.4 24.5 40.7 33.3 23.5 54.5 32.6 33.9 24.9 8.4 50.1 38.6 81.4 7.5 13.4 33.2 26.3 25.9 49.2 33.2 27.5 87.8 32.7 23.7 52.6 28.1 43.0 198.9 49.5 32.2 16.2 17.2 55.3 53.3 32.1 34.1 METTL6 MGC24132 ENSG00000206562 "Methyltransferase like 6" Q8TCB7 3 15381275-15440566 "Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 223.0;Late spermatids: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035166 Uncertain Approved Vesicles No No "Cluster 40: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA035166: AB_10602709" "unprognostic (2.73e-1)" "unprognostic (3.53e-1)" "unprognostic (2.60e-1)" "unprognostic (1.29e-2)" "unprognostic (6.60e-2)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.66e-6)" "unprognostic (3.98e-1)" "unprognostic (1.82e-1)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (2.19e-2)" "unprognostic (1.68e-2)" "unprognostic (1.27e-2)" "unprognostic (2.81e-1)" "unprognostic (3.77e-2)" "unprognostic (2.46e-1)" 7.9 7.0 13.7 7.5 13.8 5.3 9.7 13.9 15.9 9.0 6.5 6.1 6.2 8.9 8.8 8.2 9.5 6.2 7.8 14.4 13.3 6.9 6.3 6.7 9.2 11.0 10.9 12.2 6.5 9.2 8.3 9.2 11.4 8.5 7.1 13.2 5.7 9.1 7.0 8.1 5.8 10.3 11.6 7.5 7.0 18.0 14.0 10.2 9.5 7.7 10.0 7.6 6.5 16.8 13.5 21.4 23.4 20.2 21.0 23.7 59.3 24.0 24.5 28.4 29.9 12.9 17.2 22.3 16.1 22.7 24.2 11.0 23.3 20.8 30.0 15.9 25.6 21.4 20.6 19.9 39.7 20.5 18.5 21.3 25.6 34.1 17.1 22.9 26.6 22.8 22.5 22.4 28.6 28.0 22.7 17.0 23.7 14.2 25.6 17.4 29.0 22.0 17.1 18.6 10.1 18.7 20.9 19.1 19.8 16.9 27.9 17.6 18.1 22.0 14.1 22.3 22.0 24.1 43.9 26.7 23.6 19.5 21.1 7.2 8.1 12.2 9.7 10.7 9.6 7.6 9.1 9.7 9.2 9.6 9.1 10.0 4.7 11.8 10.5 12.4 9.1 6.9 13.7 13.8 13.9 15.9 14.4 13.3 11.0 10.9 11.4 11.6 14.0 16.8 5.6 3.2 5.5 20.5 6.8 4.0 8.0 13.9 10.2 17.4 5.9 6.5 5.5 1.5 7.8 9.2 6.2 9.2 5.0 1.3 5.9 10.2 223.0 5.9 10.7 7.7 1.8 6.3 37.4 13.5 21.5 8.2 4.1 5.4 5.1 14.2 5.3 2.3 9.0 20.2 38.2 2.3 4.1 4.4 4.2 121.3 9.0 6.8 5.4 9.4 8.0 11.9 13.4 17.1 22.0 9.2 2.7 9.1 10.3 5.5 4.6 4.9 9.3 15.9 6.6 8.7 8.6 31.3 17.6 6.3 2.8 11.6 8.2 11.4 3.7 5.3 MEX3C "FLJ38871, RKHD2, RNF194" ENSG00000176624 "Mex-3 RNA binding family member C" Q5U5Q3 18 51174550-51218333 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 118.4" "Group enriched" "Detected in many" 6 "Early spermatids: 555.3;Late spermatids: 514.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040603 Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA040603: AB_10805714" "unprognostic (1.09e-1)" "unprognostic (2.90e-2)" "unprognostic (8.88e-2)" "unprognostic (8.88e-3)" "unprognostic (2.04e-1)" "unprognostic (7.30e-2)" "prognostic unfavorable (8.49e-5)" "unprognostic (4.34e-2)" "unprognostic (4.43e-1)" "unprognostic (1.05e-2)" "unprognostic (1.03e-2)" "unprognostic (6.75e-2)" "unprognostic (7.99e-2)" "unprognostic (1.82e-1)" "unprognostic (1.48e-1)" "unprognostic (8.01e-2)" "unprognostic (3.17e-1)" 17.6 13.5 9.1 17.0 9.9 49.4 17.4 12.5 12.3 16.4 9.0 13.5 12.6 17.6 10.4 15.5 14.0 18.6 10.8 10.5 9.8 11.9 14.0 13.7 23.6 10.5 10.0 23.5 14.7 17.9 1.7 16.1 10.6 11.5 14.1 14.8 9.6 12.2 9.7 9.2 13.4 20.1 10.7 22.3 13.3 118.4 9.3 40.9 16.1 17.1 26.6 20.2 2.4 11.6 23.8 19.6 71.2 26.8 27.7 36.8 49.6 32.8 37.4 18.9 22.2 33.6 17.3 53.0 13.2 44.2 30.4 44.6 27.9 42.7 31.0 43.0 12.5 10.7 19.1 29.0 44.5 75.2 22.3 28.2 46.5 26.9 76.4 47.0 41.8 36.0 11.3 95.7 40.0 18.0 63.8 24.3 32.1 13.3 15.0 61.7 36.5 46.7 31.1 9.5 34.8 39.1 30.4 12.4 117.7 54.3 13.5 34.3 43.2 46.3 30.9 15.1 28.1 64.5 12.4 87.2 32.9 31.3 110.7 9.7 1.2 1.5 2.3 1.0 2.0 1.9 2.4 2.4 1.4 1.1 0.9 2.3 0.4 3.4 0.7 1.1 2.0 1.4 9.1 9.9 12.5 12.3 10.5 9.8 10.5 10.0 10.6 10.7 9.3 11.6 25.2 19.2 5.0 6.8 18.6 38.2 10.3 12.4 11.4 12.6 25.9 23.2 14.5 14.3 11.2 3.7 20.9 5.2 56.6 9.0 5.9 12.1 555.3 18.9 22.7 30.0 6.7 7.4 8.0 8.5 7.0 18.2 6.1 34.9 12.7 79.3 10.4 7.6 7.7 11.8 7.9 9.4 12.2 10.9 20.5 514.0 16.1 13.8 19.6 5.6 8.2 10.0 34.0 14.1 13.3 16.5 3.9 15.1 20.6 15.4 9.1 9.3 6.4 14.8 0.0 30.2 17.7 14.4 14.2 18.1 45.9 4.2 24.2 14.9 11.5 19.6 MFNG ENSG00000100060 "MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" O00587 22 37469063-37486393 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 69.1" "Cell type enhanced" "Detected in many" "Adipocytes: 51.4;dendritic cells: 54.6;Endothelial cells: 37.1;Hepatic stellate cells: 53.2;Kupffer cells: 45.8;monocytes: 40.6;NK-cells: 72.1;T-cells: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 174.6;HEL: 143.4;HL-60: 220.9;HMC-1: 266.9;HUVEC TERT2: 232.9;TIME: 134.7;U-698: 166.8;U-937: 201.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048936, HPA056479" Approved Approved Vesicles "Intracellular and membrane" NA NA 74000 "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA048936: AB_2680564, HPA056479: " "unprognostic (1.21e-1)" "unprognostic (4.17e-3)" "prognostic unfavorable (5.12e-4)" "prognostic favorable (1.65e-4)" "unprognostic (6.41e-3)" "unprognostic (1.00e-2)" "unprognostic (2.64e-1)" "unprognostic (2.36e-2)" "unprognostic (4.64e-2)" "unprognostic (2.91e-2)" "unprognostic (5.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (2.67e-1)" "unprognostic (4.03e-2)" "unprognostic (3.86e-2)" "unprognostic (1.43e-1)" 22.2 7.1 8.9 37.0 8.9 40.3 14.8 8.4 10.8 8.9 6.4 10.5 8.6 9.7 2.4 7.5 11.0 14.5 14.6 7.9 9.2 9.5 7.1 26.3 69.1 18.1 10.8 3.1 3.9 2.6 3.1 30.3 20.5 6.6 7.8 0.7 5.4 5.7 7.5 5.0 24.0 11.5 10.2 58.9 8.6 2.9 11.0 50.5 9.6 8.8 42.5 13.9 6.2 10.3 6.0 2.2 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.2 7.1 3.0 174.6 0.7 0.0 0.8 10.8 45.1 8.7 0.2 81.6 1.0 143.4 0.6 1.5 0.6 220.9 266.9 0.0 2.6 1.7 3.2 0.9 232.9 69.0 0.7 73.8 0.0 1.5 27.8 3.0 0.4 6.1 1.0 67.0 1.8 128.7 0.4 0.1 94.1 0.9 0.5 0.3 0.3 0.8 1.3 14.1 134.7 0.0 5.8 22.8 0.6 0.4 0.4 166.8 1.1 201.1 2.7 210.3 198.9 386.5 196.1 196.1 214.5 103.0 222.7 206.1 204.1 113.5 243.4 209.9 127.9 217.1 218.7 51.7 284.3 314.0 8.9 8.9 8.4 10.8 7.9 9.2 18.1 10.8 20.5 10.2 11.0 10.3 51.4 0.0 3.8 0.0 35.4 3.7 0.4 0.2 0.0 6.3 1.0 1.3 1.6 5.7 3.1 0.0 0.0 0.3 54.6 1.1 0.0 2.9 0.2 0.4 0.2 37.1 1.2 30.1 0.1 0.9 0.3 1.1 2.0 1.0 31.6 0.1 53.2 1.5 31.9 0.0 0.1 2.1 0.0 45.8 20.2 0.3 0.0 33.5 3.6 6.5 40.6 0.1 72.1 0.0 0.0 3.7 4.0 0.0 35.0 0.5 2.3 0.3 0.1 0.6 0.0 1.6 1.0 0.1 0.7 0.3 2.4 0.7 51.0 0.1 0.8 0.4 MFSD14A "DKFZP564L0864, HIAT1" ENSG00000156875 "Major facilitator superfamily domain containing 14A" Q96MC6 1 100038095-100083377 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 131.4" "Group enriched" "Detected in many" 5 "Early spermatids: 303.1;Late spermatids: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA073127, HPA073681" Approved Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA073127: , HPA073681: AB_2686625" "unprognostic (1.37e-1)" "unprognostic (3.49e-2)" "unprognostic (2.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.18e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (2.16e-1)" "unprognostic (7.75e-2)" "unprognostic (2.39e-1)" "unprognostic (1.11e-2)" "unprognostic (1.14e-1)" "unprognostic (1.18e-1)" "unprognostic (2.41e-1)" "unprognostic (3.84e-1)" "unprognostic (1.05e-1)" "unprognostic (5.15e-2)" 29.1 28.5 18.1 26.2 21.1 90.3 27.4 21.2 24.7 25.9 20.8 26.8 19.6 35.3 26.0 29.0 26.6 25.2 19.6 18.2 21.1 29.7 29.5 28.8 28.4 23.3 20.2 30.5 31.5 131.4 18.7 34.1 22.1 33.4 21.8 19.6 23.0 31.4 15.0 24.9 19.6 35.5 21.9 28.4 22.4 35.3 20.0 31.1 27.9 20.1 29.2 33.5 24.0 25.7 54.3 22.2 48.9 25.4 56.0 52.8 41.3 38.9 65.9 51.5 59.9 18.9 37.0 40.5 61.7 50.6 34.1 51.0 44.0 42.8 49.2 35.6 34.8 40.1 32.8 28.6 49.4 65.0 50.2 43.3 64.1 45.5 57.9 45.3 40.2 45.1 49.8 77.2 48.1 16.0 49.3 38.1 56.4 26.2 32.4 34.1 59.6 39.8 54.8 46.9 50.7 45.2 43.8 63.0 66.6 30.9 24.6 65.3 44.5 42.3 29.6 44.9 40.9 72.8 82.4 56.0 46.1 46.6 18.6 80.1 56.0 54.6 49.5 51.4 55.9 46.2 49.6 54.4 55.2 38.8 54.8 51.5 94.8 59.9 45.2 25.6 60.3 72.0 18.1 21.1 21.2 24.7 18.2 21.1 23.3 20.2 22.1 21.9 20.0 25.7 4.5 6.4 11.5 0.0 33.5 0.0 47.5 0.0 43.3 17.8 3.4 1.5 0.0 27.1 3.7 3.7 10.4 37.5 7.8 6.5 1.9 10.1 303.1 1.0 1.7 20.8 13.3 35.8 0.0 7.2 33.5 19.5 18.3 1.5 2.5 0.6 19.6 17.1 23.1 13.5 0.0 9.4 0.0 26.4 0.0 373.8 22.7 15.8 0.0 0.0 22.2 25.1 33.0 0.0 0.0 6.5 17.1 30.5 41.9 56.3 8.1 1.1 5.8 11.6 13.1 25.6 12.8 28.2 22.5 43.4 0.0 58.3 33.7 0.4 9.6 52.3 MFSD3 ENSG00000167700 "Major facilitator superfamily domain containing 3" Q96ES6 8 144509070-144511213 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 53.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056013 Uncertain Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA056013: AB_2683009" "unprognostic (7.92e-2)" "prognostic unfavorable (5.08e-4)" "unprognostic (2.00e-1)" "unprognostic (5.18e-2)" "unprognostic (6.50e-2)" "unprognostic (3.74e-2)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (9.41e-2)" "unprognostic (1.06e-1)" "unprognostic (5.49e-2)" "unprognostic (5.29e-2)" "prognostic favorable (5.44e-7)" "unprognostic (4.08e-3)" "unprognostic (2.37e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" 8.4 22.6 9.2 3.4 8.0 1.8 10.7 7.2 12.0 8.0 6.4 22.6 13.5 8.3 4.1 16.1 8.4 2.5 21.8 8.8 6.7 27.5 44.6 7.6 2.8 10.8 7.1 6.7 18.8 12.3 17.8 1.5 9.4 19.2 3.3 1.5 19.6 5.4 23.5 17.8 15.4 1.2 5.4 10.8 15.6 6.3 9.5 2.3 23.9 6.1 1.7 9.7 9.2 7.0 16.2 21.7 5.4 4.6 5.9 4.4 17.6 5.1 5.3 2.8 4.2 7.3 11.2 23.3 17.3 4.8 5.6 15.5 2.5 12.1 0.5 11.0 44.0 7.5 19.9 18.3 11.0 3.6 9.9 6.5 22.3 1.8 7.7 12.1 7.3 16.0 14.2 6.2 6.8 53.7 9.0 18.9 14.3 22.9 36.9 9.9 2.8 41.7 13.2 9.5 39.1 19.7 13.0 31.6 11.3 3.4 33.1 5.2 7.9 3.7 9.9 4.2 7.1 6.0 2.6 8.1 8.0 11.3 6.5 1.8 7.4 3.8 3.9 6.7 3.7 4.9 3.9 4.0 11.0 2.5 3.5 3.6 0.4 3.8 3.6 19.2 4.4 4.1 9.2 8.0 7.2 12.0 8.8 6.7 10.8 7.1 9.4 5.4 9.5 7.0 3.0 3.2 3.7 6.5 8.0 6.0 10.3 17.3 8.6 8.2 18.8 14.5 9.3 30.0 11.8 27.6 10.4 16.5 3.7 31.3 37.2 17.6 0.6 5.1 3.9 3.8 19.8 8.2 6.2 21.0 15.0 4.0 16.3 7.4 0.0 9.7 3.3 27.6 15.5 16.8 6.2 19.6 24.4 7.0 3.2 1.8 4.4 6.4 8.8 1.9 7.5 14.8 6.2 2.5 3.8 15.7 19.1 4.9 14.8 12.8 33.1 63.6 3.2 10.0 0.0 7.0 3.4 3.8 11.7 19.0 7.1 9.3 3.5 16.9 27.1 9.8 MIA3 "FLJ39207, KIAA0268, TANGO, TANGO1, UNQ6077" ENSG00000154305 "MIA SH3 domain ER export factor 3" Q5JRA6 1 222618097-222668007 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA055922, HPA056816" Supported Enhanced Vesicles NA NA 1400000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "HPA055922: AB_2682971, HPA056816: AB_2683243" "unprognostic (1.24e-1)" "unprognostic (7.42e-2)" "unprognostic (1.43e-1)" "unprognostic (6.60e-2)" "unprognostic (1.86e-2)" "unprognostic (8.57e-2)" "unprognostic (1.28e-3)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (5.65e-2)" "unprognostic (6.73e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (3.57e-2)" "unprognostic (1.83e-1)" "unprognostic (8.62e-3)" "unprognostic (3.26e-1)" 25.6 22.0 11.0 23.4 13.1 33.2 21.4 12.9 14.9 23.9 13.2 24.3 23.9 23.7 29.2 13.7 16.0 20.6 20.6 10.9 13.6 21.1 74.5 21.5 26.9 10.8 12.3 25.4 38.7 30.1 15.2 23.1 11.7 39.3 29.5 24.4 33.2 22.1 23.7 17.4 25.9 23.8 10.7 27.3 45.0 36.5 11.5 25.7 31.7 20.5 26.2 21.0 14.1 12.8 24.8 18.8 26.5 42.5 92.8 47.1 46.5 34.8 49.4 36.2 43.1 16.6 26.2 24.0 33.0 41.8 20.5 39.9 28.5 31.3 37.8 38.1 21.6 27.7 21.5 31.5 88.6 50.7 34.7 45.2 35.0 35.9 60.8 44.8 41.4 28.9 34.8 44.4 30.7 15.9 34.3 33.8 33.2 76.8 27.5 24.4 70.8 47.8 23.1 22.8 30.4 31.3 38.6 36.2 30.4 36.2 38.2 37.5 31.7 27.5 17.9 44.5 41.3 48.4 30.9 23.8 36.7 25.4 37.5 26.8 15.6 36.5 17.6 22.4 17.7 20.7 14.7 17.5 11.7 18.6 16.4 17.8 27.1 22.5 26.0 13.2 19.2 13.5 11.0 13.1 12.9 14.9 10.9 13.6 10.8 12.3 11.7 10.7 11.5 12.8 48.5 70.5 49.6 31.3 46.9 18.7 26.8 20.4 29.0 60.9 24.3 35.3 65.0 25.8 47.1 5.5 31.3 28.6 73.8 35.2 0.0 25.1 37.0 34.9 72.5 36.4 60.4 26.3 51.4 34.8 17.0 53.0 79.5 42.0 17.7 44.2 25.4 63.3 20.4 45.4 58.0 95.3 32.6 22.0 14.0 24.9 37.0 32.9 19.6 35.6 32.1 31.8 44.3 41.2 29.1 26.4 25.8 48.9 54.4 39.0 41.3 19.4 44.7 41.5 19.7 57.9 46.6 55.7 42.1 21.9 16.1 35.8 47.8 70.2 24.6 29.4 MITD1 LOC129531 ENSG00000158411 "Microtubule interacting and trafficking domain containing 1" Q8WV92 2 99161427-99181058 "Predicted intracellular proteins" "Cell cycle, Cell division, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036162, HPA036163" Approved Enhanced Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA036162: AB_10672236, HPA036163: AB_2674978" "prognostic favorable (5.96e-4)" "unprognostic (1.67e-2)" "unprognostic (3.09e-1)" "unprognostic (2.79e-1)" "unprognostic (2.02e-1)" "unprognostic (8.96e-2)" "prognostic unfavorable (1.47e-6)" "unprognostic (1.39e-1)" "unprognostic (5.35e-2)" "unprognostic (1.01e-2)" "unprognostic (1.09e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.32e-11)" "unprognostic (2.38e-1)" "unprognostic (2.40e-1)" "unprognostic (6.91e-2)" "prognostic favorable (5.46e-8)" 17.9 16.8 12.3 25.1 12.9 13.2 17.1 12.3 15.5 17.2 11.8 17.5 15.4 16.8 14.3 17.9 15.8 12.7 13.6 11.9 12.9 18.7 17.3 14.2 36.5 13.0 12.7 17.0 11.7 9.1 11.0 16.6 12.9 13.5 20.0 22.1 13.5 11.9 10.7 15.8 19.1 17.0 12.4 22.3 17.4 7.0 12.7 27.0 15.1 11.2 29.1 16.8 16.2 13.7 58.0 15.3 30.5 11.8 35.1 45.2 41.9 27.1 37.8 37.2 50.3 18.8 47.6 40.0 30.4 22.2 84.9 43.0 30.0 29.9 61.7 57.2 20.6 35.4 22.3 40.4 52.2 60.2 20.1 35.9 25.4 32.6 31.2 34.3 42.4 37.8 29.6 24.1 34.0 13.8 57.8 88.5 25.8 37.1 30.0 32.4 43.8 34.7 47.2 32.1 10.0 14.7 26.5 24.3 35.0 52.8 12.9 47.1 32.1 23.0 30.2 24.3 34.1 28.2 23.6 55.5 41.7 50.2 23.4 19.2 24.7 18.2 17.5 22.8 19.7 30.6 24.8 20.8 22.0 28.4 23.6 19.3 28.0 26.0 21.8 29.8 23.1 12.8 12.3 12.9 12.3 15.5 11.9 12.9 13.0 12.7 12.9 12.4 12.7 13.7 31.0 25.6 19.9 22.9 51.2 18.9 30.3 78.2 22.2 13.4 19.5 22.9 12.3 31.5 41.6 35.0 14.6 48.2 39.1 28.1 45.0 46.9 18.8 28.2 34.8 33.1 15.7 27.3 18.3 61.2 34.9 27.6 19.9 24.7 30.4 20.2 30.0 31.2 51.0 11.8 16.9 25.5 40.7 24.5 22.3 6.2 51.0 31.0 23.2 11.2 50.5 26.2 40.2 15.6 38.4 57.3 33.5 39.5 23.3 20.2 32.9 63.4 34.5 55.4 39.5 22.4 24.4 14.4 15.5 20.0 17.5 22.6 42.4 26.4 27.5 19.6 MMD "MMA, PAQR11" ENSG00000108960 "Monocyte to macrophage differentiation associated" Q15546 17 55392622-55421924 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adipose tissue: 152.2;brain: 87.5" "Cell type enhanced" "Detected in many" "Kupffer cells: 56.4;Macrophages: 85.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 110.0;HSkMC: 199.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026978 Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA026978: AB_2672068" "unprognostic (1.33e-1)" "unprognostic (2.92e-2)" "prognostic favorable (3.52e-5)" "prognostic unfavorable (3.88e-4)" "unprognostic (2.48e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (6.39e-5)" "unprognostic (8.07e-3)" "unprognostic (6.67e-2)" "unprognostic (2.15e-1)" "unprognostic (1.30e-1)" "unprognostic (1.06e-3)" "prognostic unfavorable (2.85e-4)" "unprognostic (3.71e-3)" "unprognostic (7.93e-2)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.12e-2)" 152.2 13.3 54.2 15.7 55.9 14.1 28.4 11.6 58.5 4.8 5.4 13.4 10.9 6.2 9.7 7.2 4.2 9.4 6.5 87.5 19.7 8.5 13.2 10.0 17.8 16.3 29.2 2.8 3.5 3.7 4.8 21.4 16.1 6.2 12.9 12.8 4.9 7.9 3.4 5.3 10.1 11.4 24.2 16.5 5.4 17.0 21.6 8.2 6.6 8.0 12.1 11.6 4.0 27.2 20.1 46.3 67.0 13.5 110.0 86.0 39.2 13.6 5.2 7.2 10.2 7.4 53.8 30.1 39.6 4.5 20.1 1.5 18.8 14.3 14.9 41.5 9.5 11.0 2.5 85.2 29.8 10.8 3.2 199.4 4.5 10.1 11.4 15.7 9.0 27.4 4.4 20.5 15.1 2.8 29.7 8.2 20.6 3.3 15.6 12.4 46.9 10.0 19.7 5.0 7.0 72.8 5.0 7.1 10.9 41.5 15.4 17.3 9.6 18.7 26.6 15.5 14.0 13.1 6.2 45.7 26.7 8.5 15.2 14.2 1.5 1.9 1.7 2.1 4.9 4.5 1.8 3.3 4.3 5.0 3.1 3.3 4.6 2.9 1.9 1.3 2.1 17.5 54.2 55.9 11.6 58.5 87.5 19.7 16.3 29.2 16.1 24.2 21.6 27.2 15.5 3.2 0.6 5.2 20.3 5.4 23.7 9.3 5.2 28.2 3.3 3.3 4.6 11.5 2.7 7.3 4.2 11.5 12.2 3.4 15.6 27.7 2.5 4.8 8.9 16.4 7.8 27.3 36.5 1.3 18.8 12.7 2.6 8.7 0.0 3.5 19.6 17.9 37.6 16.8 11.5 6.8 8.2 56.4 35.9 4.0 1.8 85.9 7.2 14.0 48.6 14.5 12.3 7.5 7.2 17.3 1.6 3.4 12.1 26.2 2.3 9.8 2.4 10.2 19.7 5.2 11.4 28.9 23.3 3.1 17.5 20.0 17.7 1.3 8.6 6.1 MMP1 CLG ENSG00000196611 "Matrix metallopeptidase 1" P03956 11 102789401-102798160 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation, Host-virus interaction" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 75.7;stomach 1: 47.6;urinary bladder: 52.2" "Cell type enriched" "Detected in many" 10 "Pancreatic endocrine cells: 2239.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 344.2" "Region enriched" "Detected in single" 7 "cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1139.1;HBF TERT88: 1094.4;HUVEC TERT2: 2954.4;WM-115: 1454.1" "Not detected" "Not detected" HPA004920 Approved Vesicles "Secreted to extracellular matrix" NA NA 7730000 55000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "HPA004920: AB_2667293" "unprognostic (4.11e-3)" "prognostic unfavorable (4.66e-4)" "unprognostic (4.20e-3)" "unprognostic (1.19e-3)" "unprognostic (6.46e-2)" "unprognostic (6.50e-2)" "prognostic unfavorable (4.22e-6)" "unprognostic (7.83e-3)" "unprognostic (2.94e-2)" "unprognostic (5.44e-2)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.86e-10)" "unprognostic (1.67e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-2)" "unprognostic (5.11e-2)" 0.3 0.1 0.0 26.7 0.0 0.3 0.2 0.0 1.3 0.1 0.0 6.1 7.9 10.7 0.0 4.2 0.1 75.7 0.4 0.0 0.1 1.0 0.8 6.7 0.1 0.0 0.0 0.0 1.8 0.0 0.1 7.2 0.0 0.4 6.8 0.0 6.9 0.2 0.0 0.6 13.0 1.2 0.0 2.1 47.6 0.1 0.1 0.3 0.2 0.0 1.7 52.2 0.2 0.0 0.0 0.0 0.0 1.0 0.0 1.1 0.0 517.1 1139.1 456.6 118.2 9.1 1.0 0.0 5.2 275.5 175.2 4.6 0.0 160.0 1094.4 0.0 1.0 0.0 0.0 0.0 2.9 0.0 0.5 0.3 0.8 470.1 39.6 0.1 2954.4 0.0 1.5 0.5 0.3 0.0 0.0 0.0 0.4 189.3 20.8 0.0 0.1 0.0 0.7 2.2 0.0 0.1 4.8 0.0 1.6 0.1 0.5 0.0 155.0 374.1 0.6 16.8 1.3 0.1 0.0 0.0 8.8 0.0 1454.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.3 3.2 2.6 0.0 0.2 2.3 22.4 90.4 0.0 0.0 0.0 0.0 0.1 30.0 15.8 3.7 0.0 0.0 0.0 0.2 0.0 143.7 0.0 0.1 0.2 113.2 0.0 0.0 0.1 204.8 0.1 11.5 25.5 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.0 1.9 0.4 0.0 0.0 15.5 0.0 0.0 4.2 0.0 0.0 0.0 0.0 2239.5 1.2 0.0 0.0 30.9 0.7 0.2 1.3 0.0 0.0 1.8 10.5 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 44.3 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1062.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 222.4;Extravillous trophoblasts: 467.9;Fibroblasts: 815.9;Leydig cells: 340.2;Peritubular cells: 419.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 5619.3;ASC TERT1: 1623.2;hTERT-RPE1: 6400.4;U-87 MG: 1812.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 220000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 518.9 68.3 3.9 135.1 4.0 1.2 328.9 4.9 7.8 514.1 9.4 173.8 57.4 453.6 192.6 121.5 190.6 1062.9 212.8 3.6 5.3 43.7 15.6 279.7 28.1 7.6 4.9 271.1 42.8 13.8 14.7 225.0 5.4 116.8 171.3 11.4 124.1 137.5 60.8 455.6 177.3 468.5 6.7 58.3 134.0 49.6 8.6 19.8 113.5 66.1 30.3 660.8 238.1 10.0 6.5 3.9 192.0 2.4 5619.3 1623.2 312.7 501.4 1146.1 99.4 79.0 0.2 2.1 0.5 391.7 891.0 37.0 54.2 1.2 4.6 57.0 0.7 0.9 0.7 12.9 3.0 530.6 0.4 14.8 1396.8 1.7 512.4 4.4 6400.4 651.1 0.5 0.7 2.4 334.7 0.0 0.4 8.2 152.4 0.5 1.6 0.4 46.1 0.9 16.1 7.6 3.2 345.0 93.3 0.8 2.1 849.0 1.6 36.0 924.6 1546.0 144.9 300.5 66.9 1.0 0.6 2.2 1812.3 28.3 289.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 4.9 7.8 3.6 5.3 7.6 4.9 5.4 6.7 8.6 10.0 38.4 0.0 0.5 0.0 0.0 122.1 14.1 48.8 9.1 30.5 3.1 16.8 4.4 0.0 3.1 11.0 0.0 5.6 0.5 0.1 0.0 2.5 12.5 7.7 222.4 46.9 28.2 0.0 0.0 0.4 467.9 815.9 12.2 5.4 0.0 0.0 13.2 0.1 28.2 1.7 0.2 0.1 2.0 1.6 180.7 40.2 340.2 11.8 128.1 27.2 0.0 7.7 0.0 5.0 0.0 9.3 0.0 419.0 2.8 5.6 0.0 0.2 1.1 2.5 13.1 80.0 65.3 1.2 2.8 6.6 102.3 17.2 10.3 35.2 0.0 4.4 MMP3 "STMY, STMY1" ENSG00000149968 "Matrix metallopeptidase 3" P08254 11 102835801-102843609 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 90.7;salivary gland: 286.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 20.4;Basal respiratory cells: 25.8;Early spermatids: 24.2;Extravillous trophoblasts: 13.4;Fibroblasts: 17.9;Prostatic glandular cells: 11.9;Smooth muscle cells: 10.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 59.9" "Region enriched" "Detected in some" 4 "thalamus: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "BJ: 1545.7;BJ hTERT+: 4229.3;fHDF/TERT166: 1846.6" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 3.2" HPA007875 Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA 2540000 460000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA007875: AB_1079396" "unprognostic (2.27e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.63e-3)" "unprognostic (5.11e-3)" "unprognostic (3.78e-1)" "unprognostic (5.11e-2)" "unprognostic (5.26e-6)" "unprognostic (3.46e-2)" "unprognostic (7.14e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (3.26e-2)" "unprognostic (1.22e-15)" "unprognostic (3.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (2.34e-1)" 90.7 0.1 0.3 20.1 0.4 0.0 36.6 0.2 1.6 0.3 0.1 6.1 2.4 38.1 0.2 0.8 0.2 1.9 0.2 0.4 1.6 0.4 1.6 0.3 0.0 0.4 0.4 0.1 0.3 0.1 0.9 0.4 0.3 2.2 2.3 0.0 286.1 2.2 39.6 63.7 4.5 1.6 0.3 0.0 10.5 0.1 7.3 0.1 2.6 0.4 1.3 13.9 0.5 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1545.7 4229.3 27.0 8.7 0.1 0.2 0.0 0.0 1846.6 96.9 0.0 0.1 0.1 45.1 0.0 0.0 0.0 0.0 1.0 0.7 0.0 0.0 4.6 0.2 122.0 5.3 0.0 0.0 0.0 0.2 0.3 4.7 0.0 0.0 0.0 0.2 0.4 0.9 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.3 0.0 0.0 0.9 0.0 0.3 0.0 140.5 13.1 1.6 0.5 0.0 0.0 0.2 56.8 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 1.6 0.4 1.6 0.4 0.4 0.3 0.3 7.3 0.3 0.0 3.2 0.0 0.0 0.0 8.4 20.4 25.8 0.0 0.0 0.1 0.1 0.3 4.3 7.6 0.0 0.0 0.1 0.0 0.0 0.0 0.8 24.2 0.0 0.3 0.5 0.0 0.0 0.2 1.4 13.4 17.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.1 0.0 2.2 1.2 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.5 4.0 0.0 0.0 11.9 1.0 0.9 0.1 0.0 0.0 1.8 10.2 0.0 1.8 0.0 3.4 0.3 0.6 0.0 0.8 7.4 MMP8 CLG1 ENSG00000118113 "Matrix metallopeptidase 8" P22894 11 102711796-102727050 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "bone marrow: 501.1" "Group enriched" "Detected in some" 6 "Hofbauer cells: 4.0;Macrophages: 1.5" "Cancer enriched" "Detected in single" 17 "melanoma: 5.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 1.7" "Cell line enriched" "Detected in some" 8 "WM-115: 70.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021221, HPA021763, HPA022935" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 360000 "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA021221: AB_1854043, HPA021763: , HPA022935: AB_1854044" "unprognostic (3.03e-1)" "unprognostic (8.49e-5)" "unprognostic (1.08e-2)" "unprognostic (3.95e-3)" "unprognostic (1.80e-1)" "unprognostic (1.01e-2)" "unprognostic (7.68e-3)" "unprognostic (1.27e-1)" "unprognostic (4.92e-2)" "unprognostic (6.64e-3)" "unprognostic (2.45e-6)" "unprognostic (2.33e-4)" "unprognostic (1.33e-1)" "unprognostic (4.97e-1)" "unprognostic (2.30e-2)" 0.5 0.0 0.0 0.3 0.1 501.1 0.2 0.1 0.2 0.0 0.2 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.6 4.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.2 0.0 13.8 0.1 0.0 0.6 2.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.9 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Adipocytes: 229.3;Endothelial cells: 127.1;Hepatic stellate cells: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 89.2;HUVEC TERT2: 196.6;TIME: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 84000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" 63.2 13.9 14.0 10.1 12.7 1.5 54.5 11.5 12.5 20.6 11.0 14.2 10.5 28.1 13.8 16.9 22.7 16.6 38.8 11.4 11.9 22.0 8.6 32.1 9.7 13.6 12.4 23.1 10.5 10.6 7.6 73.8 13.7 14.1 8.9 3.0 26.6 28.7 26.8 38.9 13.8 27.3 13.2 34.6 11.9 15.3 15.8 6.5 25.8 32.5 13.3 32.3 19.1 12.0 11.4 2.9 0.4 0.2 1.2 6.3 7.1 4.1 11.1 4.8 6.8 6.4 89.2 0.1 39.5 7.6 11.6 21.9 0.0 5.2 6.4 8.1 0.0 2.3 10.2 0.2 0.9 0.0 4.6 1.5 26.4 5.7 38.6 13.0 196.6 2.4 2.1 35.0 1.8 7.1 0.4 4.4 2.0 0.4 4.9 0.2 0.1 0.1 2.0 17.5 4.8 0.0 3.1 3.7 1.4 0.9 14.9 1.2 237.1 1.9 11.0 1.9 0.1 2.6 4.0 0.1 5.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.0 12.7 11.5 12.5 11.4 11.9 13.6 12.4 13.7 13.2 15.8 12.0 229.3 0.0 5.8 1.6 0.3 9.4 0.9 0.0 4.6 0.2 1.4 2.0 13.2 5.7 0.7 1.8 0.0 0.7 0.4 0.0 0.0 0.1 1.0 0.3 0.4 127.1 0.0 2.7 0.9 0.0 0.1 8.1 0.0 0.5 0.0 0.2 182.0 4.1 1.7 0.0 1.2 0.0 0.0 6.5 4.4 2.8 2.5 0.7 3.6 15.9 0.0 0.7 0.0 1.0 0.1 0.0 0.0 3.0 0.1 0.6 0.5 0.2 0.0 0.6 6.6 3.9 9.4 1.8 2.3 2.2 7.7 0.3 0.8 3.6 0.2 1.0 MPV17L "FLJ39599, MLPH1, MLPH2, MPV17L1" ENSG00000156968 "MPV17 mitochondrial inner membrane protein like" Q2QL34 16 15395754-15413271 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 14.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 29.5;SK-BR-3: 8.2" "Low region specificity" "Detected in all" HPA041180 Approved Supported Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA041180: AB_10794266" "unprognostic (9.65e-2)" "unprognostic (8.74e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-3)" "unprognostic (6.68e-2)" "unprognostic (2.84e-1)" "unprognostic (2.73e-1)" "unprognostic (4.38e-3)" "unprognostic (8.41e-2)" "unprognostic (8.99e-3)" "unprognostic (8.70e-2)" "unprognostic (6.36e-3)" "prognostic favorable (1.48e-11)" "unprognostic (2.84e-1)" "unprognostic (7.60e-2)" "unprognostic (6.61e-3)" "unprognostic (3.87e-2)" 1.8 2.5 1.2 1.8 0.1 4.4 6.4 1.9 2.2 2.8 0.0 2.3 3.4 2.0 0.3 1.0 1.8 2.4 1.6 0.1 0.0 3.3 9.1 0.9 2.3 0.1 0.0 2.1 14.1 2.4 3.2 0.6 0.3 2.0 1.0 4.4 7.1 1.8 8.0 4.5 2.3 0.8 0.0 1.8 1.8 1.0 0.5 0.2 2.2 2.4 0.6 1.9 1.3 0.4 1.0 1.9 0.8 0.8 0.2 0.1 1.2 0.5 0.0 0.0 0.0 1.9 3.4 1.5 1.3 0.6 0.5 1.5 3.0 0.0 0.0 1.2 0.8 5.9 4.6 3.9 0.3 3.6 29.5 0.3 0.4 0.1 0.2 0.5 0.0 1.6 2.3 3.3 0.1 1.9 1.4 2.3 1.7 0.3 0.1 2.0 0.6 1.6 0.5 0.8 4.8 1.6 2.7 8.2 0.2 0.9 1.8 2.6 2.6 1.3 0.8 1.1 1.1 1.4 0.6 1.7 0.7 1.7 0.5 1.7 1.2 0.2 0.8 0.9 0.6 0.8 0.5 0.8 0.4 1.2 0.4 0.8 1.8 1.1 0.4 0.7 0.4 0.6 1.2 0.1 1.9 2.2 0.1 0.0 0.1 0.0 0.3 0.0 0.5 0.4 2.5 6.4 8.8 3.9 2.0 7.9 14.4 8.2 0.0 12.8 11.4 6.0 6.0 14.3 13.1 0.0 10.4 0.5 4.1 2.7 15.6 7.5 4.6 5.4 9.2 6.6 1.2 2.1 5.6 12.9 0.5 8.1 2.0 10.7 6.3 7.6 4.2 29.1 1.0 8.4 5.9 8.7 2.0 13.6 20.6 0.8 7.2 6.0 21.4 2.8 0.7 6.2 0.0 7.5 3.2 5.9 15.3 14.3 1.4 9.6 9.3 19.9 21.0 16.6 0.0 23.5 6.7 9.0 2.0 0.6 11.5 0.5 9.9 4.4 12.1 10.1 MREG "DSU, FLJ10116, WDT2" ENSG00000118242 Melanoregulin Q8N565 2 215942584-216034096 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 46.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Glandular and luminal cells: 34.1;Rod photoreceptor cells: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 82.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068583 Approved Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" Vesicles "HPA068583: AB_2686009" "unprognostic (4.53e-2)" "unprognostic (1.12e-1)" "unprognostic (3.05e-1)" "unprognostic (1.20e-2)" "unprognostic (3.24e-1)" "unprognostic (1.13e-2)" "unprognostic (3.70e-1)" "unprognostic (7.37e-2)" "unprognostic (2.39e-1)" "unprognostic (5.85e-3)" "unprognostic (8.11e-3)" "unprognostic (8.93e-2)" "unprognostic (6.38e-3)" "unprognostic (6.62e-3)" "unprognostic (6.92e-2)" "prognostic favorable (4.20e-4)" "unprognostic (9.99e-2)" 5.9 8.2 3.9 5.4 8.9 5.9 21.4 17.9 5.6 6.7 6.2 5.6 6.4 3.4 5.0 29.8 5.8 2.8 0.7 4.6 4.5 5.4 17.8 10.3 10.8 5.6 4.7 2.5 2.2 7.3 7.6 7.7 5.9 2.4 5.8 46.9 4.9 6.1 2.7 20.2 5.5 1.8 3.3 4.4 6.8 1.1 6.5 9.9 6.6 0.9 15.1 5.5 14.3 5.0 20.9 5.1 5.9 3.5 3.9 2.1 13.1 7.0 5.6 4.6 8.9 24.3 15.5 6.7 6.0 4.3 11.5 13.0 17.9 26.5 10.1 14.1 15.1 10.6 5.6 43.5 2.3 6.0 3.9 3.9 11.2 5.3 7.4 4.6 4.0 15.2 5.3 17.8 2.9 82.8 17.0 5.7 23.3 12.4 4.8 9.8 13.9 10.7 12.3 29.3 16.4 8.6 4.4 36.4 40.3 13.7 20.2 2.8 0.5 9.8 2.5 5.0 10.7 23.0 15.3 17.5 6.0 22.2 7.5 1.6 0.1 0.2 0.7 0.1 1.2 1.1 0.6 1.1 0.1 0.6 0.3 0.5 0.8 0.8 0.2 2.1 1.0 0.1 3.9 8.9 17.9 5.6 4.6 4.5 5.6 4.7 5.9 3.3 6.5 5.0 0.6 3.2 13.4 7.8 4.3 2.7 12.1 0.6 9.6 14.4 24.1 12.1 0.8 2.8 9.2 7.3 60.5 21.7 8.5 3.8 3.9 3.2 0.3 14.0 1.9 1.1 1.8 2.1 21.1 2.5 4.7 1.8 5.6 34.1 1.3 0.6 1.4 8.3 13.4 1.7 21.4 1.8 2.0 0.8 3.0 0.0 2.5 4.0 5.4 6.5 21.3 7.6 2.1 8.5 12.8 7.5 4.6 7.5 7.0 7.0 3.1 1.1 3.0 40.1 6.6 1.2 1.2 1.1 4.6 28.7 1.6 25.9 4.0 1.0 2.9 22.6 MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172014-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 580.8;Hofbauer cells: 376.8;Kupffer cells: 1649.6;Langerhans cells: 470.0;Macrophages: 675.9;monocytes: 429.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 406.4;classical monocyte: 1095.3;intermediate monocyte: 345.6;myeloid DC: 638.8;plasmacytoid DC: 454.4" "Group enriched" "Detected in all" 74 "dendritic cells: 638.8;granulocytes: 406.4;monocytes: 1095.3" "Cell line enriched" "Detected in some" 8 "THP-1: 47.9" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA011391: AB_10603876, HPA076623: AB_2686809" "unprognostic (1.17e-1)" "prognostic favorable (6.33e-4)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (3.20e-1)" "unprognostic (4.75e-3)" "unprognostic (1.06e-1)" "unprognostic (4.66e-2)" "unprognostic (3.94e-2)" "unprognostic (2.97e-2)" 72.6 42.3 10.7 57.5 10.9 33.5 40.0 10.8 22.5 28.1 14.7 41.0 27.8 14.3 9.6 25.7 16.8 61.4 22.8 10.0 11.8 11.5 108.6 56.4 109.1 15.8 13.7 12.3 7.8 8.7 9.8 65.2 14.8 12.4 54.9 1.4 16.0 18.3 5.3 7.3 45.1 52.6 12.4 121.5 24.5 7.8 13.6 32.2 10.0 17.7 47.6 59.9 8.6 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 5.7 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 4.1 0.0 406.4 1095.3 8.2 1.6 345.6 3.4 9.6 2.2 1.4 638.8 1.5 1.0 1.0 72.8 2.1 24.4 454.4 1.9 752.8 10.7 10.9 10.8 22.5 10.0 11.8 15.8 13.7 14.8 12.4 13.6 17.6 5.3 6.4 22.9 0.0 16.1 9.3 0.6 0.0 1.2 0.3 2.2 8.0 3.3 17.2 2.5 3.7 0.0 2.0 220.6 0.3 0.0 0.0 2.2 0.4 0.2 12.8 0.0 43.9 0.1 0.0 2.7 4.3 2.6 0.2 13.9 0.1 580.8 20.5 376.8 0.0 0.1 0.1 0.0 1649.6 470.0 5.1 1.5 675.9 14.2 40.3 429.2 0.0 11.3 0.5 0.1 0.0 1.2 0.0 2.0 0.2 0.0 0.5 1.5 0.6 46.0 3.0 4.4 0.5 1.1 2.4 8.0 2.1 10.4 0.1 0.2 0.3 MS4A6E ENSG00000166926 "Membrane spanning 4-domains A6E" Q96DS6 11 60334831-60396596 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 35.6" "Cell type enriched" "Detected in some" 10 "Early spermatids: 1211.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA076623 Approved Vesicles NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA076623: AB_2686809" "unprognostic (2.58e-1)" "unprognostic (3.35e-1)" "unprognostic (3.47e-1)" "unprognostic (6.81e-3)" "unprognostic (4.55e-4)" "unprognostic (1.08e-1)" "unprognostic (1.71e-1)" "unprognostic (1.76e-1)" 2.1 0.0 0.0 1.1 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 35.6 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1211.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 114.8 6.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MTFR2 "DUFD1, FAM54A" ENSG00000146410 "Mitochondrial fission regulator 2" Q6P444 6 136231024-136250335 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.3;lymphoid tissue: 6.4;testis: 7.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 23.6;Spermatocytes: 27.6;Spermatogonia: 13.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA029792, HPA029794" Approved Uncertain Vesicles NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "HPA029792: AB_10600210, HPA029794: AB_10600535" "unprognostic (6.49e-3)" "unprognostic (6.29e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (9.64e-4)" "unprognostic (3.93e-1)" "unprognostic (1.75e-2)" "unprognostic (4.60e-6)" "prognostic unfavorable (8.28e-4)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (6.27e-2)" "unprognostic (6.54e-2)" "unprognostic (1.11e-16)" "unprognostic (8.82e-3)" "unprognostic (1.55e-1)" "unprognostic (4.10e-2)" "unprognostic (3.64e-2)" 0.8 0.5 0.4 3.6 0.3 16.3 1.0 0.4 0.6 0.6 0.2 2.9 2.8 0.5 0.3 2.6 0.3 0.3 0.3 0.4 0.3 0.6 0.4 1.2 6.4 0.4 0.5 0.3 0.4 0.0 0.4 1.8 0.3 0.4 3.8 0.5 0.8 0.2 1.2 1.9 2.3 1.1 0.4 2.2 1.2 7.0 0.4 6.2 0.3 0.1 5.3 0.8 0.9 0.4 15.2 11.5 9.7 18.2 1.6 2.8 17.4 19.6 13.6 22.8 31.7 20.7 12.2 39.2 11.7 7.9 30.1 23.1 22.3 14.4 33.8 22.1 17.1 31.0 7.8 18.9 1.0 57.4 28.1 2.3 3.1 25.5 16.1 2.7 12.4 33.8 33.9 29.6 17.2 20.2 32.5 47.8 9.8 20.2 14.1 29.3 15.5 19.7 9.9 11.6 7.7 7.6 12.4 21.5 11.3 11.9 9.1 39.1 6.8 11.3 11.8 40.2 30.4 11.2 28.3 26.1 6.5 38.5 17.6 0.0 0.2 0.0 0.3 0.9 0.1 0.4 0.4 0.7 0.9 0.3 0.0 0.4 0.0 0.0 0.7 0.7 0.7 0.3 0.4 0.3 0.4 0.6 0.4 0.3 0.4 0.5 0.3 0.4 0.4 0.4 2.0 0.0 1.1 0.0 2.2 1.0 0.6 3.1 0.0 0.0 3.4 3.6 0.4 0.0 2.3 0.0 0.0 8.4 1.3 2.2 0.0 1.1 7.9 2.4 1.3 1.7 0.0 9.9 0.5 2.5 23.6 1.5 2.6 2.5 1.3 3.5 0.7 0.5 6.6 0.0 0.4 2.1 4.1 3.8 2.1 5.9 0.3 2.5 0.0 1.0 2.3 0.0 1.0 0.5 0.0 1.3 0.4 0.0 7.4 1.2 1.3 1.4 2.5 0.0 0.0 5.3 1.8 27.6 13.0 5.3 0.3 3.0 3.1 0.8 4.6 0.9 MTMR1 ENSG00000063601 "Myotubularin related protein 1" Q13613 X 150692971-150765108 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 79.3;Excitatory neurons: 61.2;Inhibitory neurons: 58.1;Oligodendrocyte precursor cells: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-698: 104.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018502, HPA075953" Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA018502: AB_1854185, HPA075953: " "unprognostic (2.37e-2)" "unprognostic (1.64e-3)" "unprognostic (2.07e-1)" "unprognostic (1.05e-2)" "unprognostic (4.34e-2)" "unprognostic (1.14e-1)" "unprognostic (1.97e-1)" "unprognostic (1.34e-1)" "unprognostic (4.35e-2)" "unprognostic (3.16e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-2)" "unprognostic (1.67e-2)" "unprognostic (1.32e-2)" "unprognostic (1.93e-1)" "unprognostic (3.19e-1)" "unprognostic (8.40e-2)" 6.7 7.2 11.3 11.1 13.0 11.9 12.5 11.7 13.0 9.3 7.1 10.2 9.0 7.9 7.1 20.6 9.7 7.2 12.2 17.3 10.8 8.3 9.0 9.5 21.8 7.5 10.0 8.5 10.0 17.9 9.2 14.2 7.6 10.9 9.4 22.1 12.4 10.9 22.9 21.4 10.4 7.3 9.2 14.3 10.7 8.0 11.9 31.3 10.0 16.0 25.5 12.6 13.5 8.7 32.3 20.3 21.5 17.7 4.9 5.7 28.8 28.1 36.0 28.0 39.4 19.8 24.9 70.2 40.1 22.9 27.1 28.4 43.9 40.8 43.2 28.4 26.3 4.4 31.6 8.5 14.5 20.7 14.6 15.6 27.7 30.8 0.4 26.8 17.1 22.9 13.8 17.5 20.3 27.7 30.6 5.3 9.9 35.9 30.3 16.0 34.1 31.2 22.0 36.4 31.9 19.9 10.7 23.7 8.8 17.0 30.3 11.8 21.7 18.3 14.6 2.3 42.1 22.2 24.6 104.8 3.7 13.3 14.4 0.0 0.5 5.0 2.1 0.9 1.5 1.7 2.3 1.9 1.4 1.9 2.0 2.8 1.5 3.9 0.9 5.0 3.2 1.2 11.3 13.0 11.7 13.0 17.3 10.8 7.5 10.0 7.6 9.2 11.9 8.7 3.7 16.0 6.5 79.3 11.4 11.2 11.0 8.0 6.8 0.0 7.8 5.5 8.2 2.8 7.5 5.5 0.0 10.1 19.3 4.6 0.0 5.9 0.0 10.0 3.7 3.6 9.6 6.5 61.2 6.6 7.3 4.5 7.7 9.2 1.3 4.8 2.9 8.0 4.6 0.0 58.1 5.5 8.2 9.4 8.8 1.7 5.6 4.8 3.6 30.0 6.2 0.0 8.2 54.8 22.6 10.6 8.6 5.3 7.9 11.0 3.8 3.1 8.4 0.0 6.6 6.7 3.9 2.5 3.0 10.3 16.8 10.4 8.8 5.9 5.9 12.5 MTMR2 "CMT4B, KIAA1073" ENSG00000087053 "Myotubularin related protein 2" Q13614 11 95821766-95925315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 120.1;Oligodendrocytes: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049831 Approved Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA049831: AB_2680904" "unprognostic (1.71e-2)" "unprognostic (2.55e-3)" "unprognostic (7.81e-3)" "unprognostic (4.16e-1)" "unprognostic (4.18e-3)" "unprognostic (5.36e-2)" "prognostic unfavorable (1.61e-8)" "unprognostic (3.23e-3)" "unprognostic (3.42e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.60e-4)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (1.54e-1)" "unprognostic (1.50e-1)" "unprognostic (1.14e-1)" "unprognostic (8.03e-3)" 14.7 9.3 11.0 11.2 16.8 4.4 11.8 16.3 18.3 12.2 12.2 12.9 7.1 12.3 6.2 14.7 12.4 14.3 13.5 10.8 14.3 16.4 4.3 12.3 9.5 15.1 14.4 11.5 7.8 12.7 6.4 24.5 15.8 16.1 13.9 18.6 20.5 11.4 6.2 8.2 8.3 18.0 13.5 8.6 13.0 31.0 14.1 15.1 9.9 8.9 12.1 15.2 10.4 22.4 24.1 25.3 54.1 39.2 19.2 29.0 47.5 43.3 37.9 42.4 37.8 57.3 47.1 16.2 50.3 45.5 35.9 30.9 47.7 48.2 38.9 30.8 21.3 31.5 55.0 33.0 42.8 59.3 26.7 24.0 31.2 56.6 54.5 41.8 64.4 35.4 44.7 14.2 39.6 17.9 29.0 27.2 46.6 59.0 34.9 23.2 32.2 16.8 43.9 125.0 35.6 40.6 43.6 36.4 19.2 35.1 27.6 26.5 64.4 47.7 45.1 34.4 41.1 13.1 42.4 14.3 20.4 15.6 50.6 9.8 3.9 1.7 12.4 4.7 13.4 5.8 7.9 15.7 7.6 4.9 4.0 11.3 0.9 14.1 7.2 3.7 8.1 7.8 11.0 16.8 16.3 18.3 10.8 14.3 15.1 14.4 15.8 13.5 14.1 22.4 19.6 3.2 8.6 28.7 9.6 10.3 15.0 9.0 8.6 0.0 8.0 6.7 17.3 0.0 11.6 9.2 0.0 9.0 8.8 9.1 9.8 17.8 74.8 18.1 14.1 20.2 16.2 12.8 69.8 16.9 34.3 17.0 9.7 8.7 19.0 49.1 11.0 1.0 12.5 0.0 37.5 9.8 24.4 10.3 8.2 120.1 11.1 8.3 3.6 40.3 6.8 0.0 14.4 63.8 226.6 17.7 4.7 12.0 7.0 15.1 6.0 29.3 17.0 0.0 32.9 7.9 29.0 46.8 19.2 15.4 6.0 9.0 8.8 12.9 10.6 15.6 MUC5B "MG1, MUC5" ENSG00000117983 "Mucin 5B, oligomeric mucus/gel-forming" Q9HC84 11 1223066-1262172 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "salivary gland: 2621.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 443.2;Distal enterocytes: 158.4;Intestinal goblet cells: 210.1;Undifferentiated cells: 183.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "OE19: 113.9;PC-3: 120.0" "Not detected" "Not detected" "HPA008246, CAB009396" Enhanced Supported Vesicles "Secreted in other tissues" NA NA 1300000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB009396: AB_2282256, HPA008246: AB_1854203" "unprognostic (2.01e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (2.76e-3)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (4.89e-2)" "unprognostic (7.80e-3)" "unprognostic (3.75e-1)" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (8.95e-2)" "unprognostic (2.57e-7)" "unprognostic (2.71e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-1)" "unprognostic (8.13e-2)" 0.1 0.7 0.2 2.0 0.1 0.0 1.3 0.0 0.4 229.4 0.0 58.0 0.1 0.3 0.0 101.0 1.1 221.3 0.1 0.0 0.0 0.1 2.4 7.5 0.0 0.1 0.0 0.1 9.8 0.0 0.4 0.0 0.0 0.6 17.1 0.0 2621.9 0.0 0.3 0.4 2.6 0.6 0.0 0.0 6.9 0.3 0.0 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.1 0.2 0.0 113.9 120.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 2.3 0.0 0.0 6.7 0.6 0.0 6.4 4.3 12.4 443.2 64.0 0.0 0.0 0.1 0.0 158.4 0.0 0.9 0.0 1.4 0.8 0.9 24.5 0.0 0.1 0.0 0.1 1.1 12.8 7.2 4.5 0.0 0.0 1.2 0.2 0.0 0.0 210.1 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 53.4 0.0 1.4 1.3 0.1 0.2 24.5 0.0 0.0 0.0 3.0 0.0 0.5 1.6 0.0 0.1 0.7 0.1 183.1 1.1 MVB12A "FAM125A, FLJ32495" ENSG00000141971 "Multivesicular body subunit 12A" Q96EY5 19 17405722-17433724 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041885, HPA042231" Approved Supported Vesicles NA No "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041885: AB_10964218, HPA042231: AB_10961043" "unprognostic (1.34e-2)" "prognostic favorable (3.26e-4)" "unprognostic (1.48e-1)" "unprognostic (2.35e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-2)" "unprognostic (5.96e-3)" "unprognostic (8.49e-2)" "unprognostic (1.80e-1)" "unprognostic (1.77e-1)" "unprognostic (9.93e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-1)" "unprognostic (2.54e-1)" "unprognostic (2.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.33e-2)" 21.3 28.4 10.5 17.3 11.5 18.2 21.4 11.4 12.3 18.6 11.8 16.7 29.1 17.3 7.4 29.5 22.0 18.7 13.1 10.0 10.3 20.2 19.9 15.5 21.7 14.0 11.0 34.0 20.0 22.2 7.4 19.2 11.6 13.7 11.6 1.2 24.2 17.5 14.4 24.7 22.0 11.6 12.3 22.3 20.9 5.2 11.4 24.0 21.2 12.4 19.3 17.0 18.0 13.5 51.2 23.4 12.1 33.9 15.7 28.8 71.1 18.3 28.4 33.8 40.8 20.1 60.5 32.7 52.7 28.2 28.8 25.5 19.5 35.5 9.0 37.6 60.7 9.5 41.8 44.0 50.3 13.0 29.1 28.2 28.5 29.1 18.0 25.5 40.7 29.9 26.8 65.2 15.6 32.2 24.6 26.2 17.0 40.8 63.9 34.7 14.8 53.1 32.4 21.2 25.3 40.7 19.6 30.2 77.6 10.9 40.1 30.9 21.7 31.5 18.4 35.1 20.5 59.3 72.9 35.0 34.1 49.3 38.9 57.4 61.7 42.9 33.0 66.9 31.0 23.3 34.0 32.0 60.5 29.8 28.0 27.5 36.0 38.2 53.4 53.3 57.2 36.2 10.5 11.5 11.4 12.3 10.0 10.3 14.0 11.0 11.6 12.3 11.4 13.5 67.5 9.6 8.2 5.9 16.4 39.0 41.4 65.1 42.1 5.3 53.6 61.8 5.6 48.6 33.5 46.0 6.2 60.7 18.1 85.0 54.8 78.7 13.5 30.1 26.8 47.7 26.5 8.4 2.2 48.4 99.0 38.6 43.3 30.2 21.6 45.7 62.4 28.0 72.3 3.3 3.2 48.5 50.8 44.9 30.8 16.3 43.5 31.2 32.0 11.2 46.7 32.7 19.6 4.0 7.3 63.4 84.1 47.0 23.5 19.0 104.4 61.3 36.4 13.8 6.6 22.8 40.9 11.8 12.3 58.3 43.9 40.6 21.2 44.3 57.1 45.0 MYBPHL ENSG00000221986 "Myosin binding protein H like" A2RUH7 1 109292365-109307011 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "heart muscle: 105.8" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 156.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;RH-30: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA077633 Approved Vesicles NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA077633: " "unprognostic (6.07e-3)" "unprognostic (1.43e-1)" "unprognostic (2.78e-1)" "unprognostic (1.17e-2)" "unprognostic (1.47e-1)" "unprognostic (1.37e-1)" "unprognostic (1.80e-2)" "unprognostic (1.24e-2)" "unprognostic (5.53e-2)" "unprognostic (5.89e-1)" "unprognostic (5.22e-3)" "unprognostic (4.10e-1)" "unprognostic (7.05e-9)" "unprognostic (6.01e-2)" "unprognostic (1.53e-1)" "unprognostic (5.81e-2)" "unprognostic (2.64e-1)" 0.0 0.1 0.6 0.0 1.2 0.0 0.0 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.4 0.6 2.3 0.0 105.8 2.2 0.5 0.0 0.0 1.2 0.0 0.6 0.6 0.0 0.0 0.0 3.0 0.0 0.6 0.0 0.0 2.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.0 0.5 0.5 0.6 0.0 0.0 0.6 0.0 0.1 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.4 2.8 2.2 0.5 0.6 0.6 0.6 0.3 0.6 2.4 0.0 0.0 5.1 0.3 0.0 0.0 0.1 0.7 0.0 1.8 0.1 0.1 156.7 0.0 1.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.0 3.1 0.0 0.0 11.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.5 2.2 0.1 0.0 0.7 0.0 0.0 0.0 0.1 0.8 11.1 0.0 25.0 1.6 0.3 0.6 0.0 0.1 0.0 0.1 0.1 0.0 0.4 MYCBPAP "AMAP-1, DKFZp434N1415" ENSG00000136449 "MYCBP associated protein" Q8TBZ2 17 50508384-50531501 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 65.1" "Cell type enhanced" "Detected in many" "Early spermatids: 224.2;Late spermatids: 145.2;Respiratory ciliated cells: 40.4;Spermatocytes: 69.9;Theca cells: 54.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 4.4;JURKAT: 3.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA023257, HPA024405" Enhanced Approved Vesicles NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA023257: AB_2671126, HPA024405: " "unprognostic (2.05e-2)" "unprognostic (1.79e-2)" "unprognostic (9.13e-3)" "unprognostic (3.98e-5)" "unprognostic (8.62e-4)" "unprognostic (3.65e-2)" "unprognostic (1.52e-3)" "unprognostic (1.61e-1)" "unprognostic (2.38e-3)" "unprognostic (1.11e-1)" "unprognostic (7.32e-4)" "unprognostic (2.52e-1)" "unprognostic (1.39e-4)" "unprognostic (7.15e-2)" "unprognostic (1.97e-1)" "unprognostic (7.37e-2)" "unprognostic (2.02e-2)" 0.7 0.8 1.7 0.6 1.8 1.3 0.4 2.4 3.4 1.2 3.4 0.4 0.2 0.9 1.1 0.8 5.3 1.0 0.6 1.3 1.0 0.8 0.2 1.5 1.0 2.9 2.4 2.5 0.2 0.4 0.9 0.3 1.4 1.0 0.4 1.1 0.8 1.3 1.1 1.0 0.3 0.9 1.5 0.6 0.4 65.1 1.6 0.9 0.8 0.3 0.6 0.3 0.5 1.1 0.1 0.8 0.3 0.3 0.8 0.4 0.8 0.7 0.3 0.2 0.2 0.4 2.0 0.2 0.1 0.2 0.8 0.3 0.1 0.9 0.2 4.4 0.2 1.3 1.3 0.4 0.7 0.1 0.2 1.2 0.2 0.4 1.8 0.8 0.6 3.8 0.2 0.4 0.6 0.1 0.2 0.3 0.1 0.1 0.5 0.1 0.2 0.2 0.0 0.2 0.6 1.6 0.3 0.2 0.1 0.5 0.3 0.8 2.0 0.3 0.4 0.1 0.1 2.3 0.8 0.1 0.5 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 1.7 1.8 2.4 3.4 1.3 1.0 2.9 2.4 1.4 1.5 1.6 1.1 0.3 0.0 1.7 7.2 0.7 0.1 1.4 0.7 0.0 3.6 0.4 0.3 0.9 0.0 6.5 1.8 0.0 2.4 1.7 0.4 0.0 0.1 224.2 18.6 1.2 1.1 0.0 3.6 2.5 0.4 0.3 2.0 0.0 0.6 0.0 5.6 0.0 0.0 0.4 0.0 2.2 1.8 0.0 0.6 0.5 145.2 6.8 0.6 0.0 2.8 0.0 4.3 3.1 0.5 1.0 0.1 0.1 3.8 0.6 1.1 1.4 0.2 40.4 0.5 0.0 2.7 1.4 69.9 7.6 0.1 0.4 0.1 1.4 54.9 0.4 0.8 MYO16 "KIAA0865, Myo16b, MYR8, NYAP3, PPP1R107" ENSG00000041515 "Myosin XVI" Q9Y6X6 13 108596152-109208005 "Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.4" "Group enriched" "Detected in some" 8 "Inhibitory neurons: 460.0;Oligodendrocyte precursor cells: 299.6" "Cancer enhanced" "Detected in some" "glioma: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.0;SH-SY5Y: 4.5;U-2197: 2.7" "Region enhanced" "Detected in all" "olfactory bulb: 72.6" "Low region specificity" "Detected in all" "HPA040110, HPA058769, HPA071948" Uncertain Approved Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA040110: AB_10796339, HPA058769: AB_2683814, HPA071948: AB_2686475" "unprognostic (7.55e-3)" "unprognostic (7.74e-3)" "unprognostic (4.52e-4)" "unprognostic (5.12e-3)" "unprognostic (1.38e-1)" "unprognostic (5.81e-2)" "unprognostic (1.20e-2)" "unprognostic (2.16e-1)" "unprognostic (2.53e-1)" "unprognostic (6.50e-2)" "unprognostic (9.01e-3)" "unprognostic (5.29e-2)" "unprognostic (4.68e-4)" "unprognostic (4.26e-2)" "unprognostic (3.21e-2)" "unprognostic (7.06e-2)" "unprognostic (2.34e-2)" 1.4 0.7 2.5 0.2 4.9 0.0 0.2 1.2 3.7 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.9 5.4 1.8 0.0 1.9 0.2 0.2 0.6 1.5 0.0 0.1 0.0 1.7 0.1 2.3 0.2 0.1 0.4 0.1 0.7 0.0 0.1 0.0 0.4 2.6 0.0 0.0 1.1 2.6 0.0 0.0 0.2 0.3 0.0 0.2 0.9 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.9 1.2 3.7 5.4 1.8 0.6 1.5 2.3 2.6 2.6 0.9 1.0 0.0 0.6 19.6 0.0 0.3 0.0 0.4 0.0 4.2 0.1 0.3 3.7 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.5 11.3 0.5 1.1 0.1 0.0 3.4 44.6 0.0 0.1 0.8 0.0 0.3 1.3 0.1 0.0 5.9 0.1 0.0 460.0 0.0 0.0 0.0 0.3 11.4 0.9 0.1 1.8 8.4 0.0 2.8 0.0 299.6 4.7 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.4 0.0 0.1 0.1 5.0 7.7 0.0 0.0 0.3 0.3 1.6 0.0 0.0 MYT1L "KIAA1106, NZF1, ZC2H2C2, ZC2HC4B" ENSG00000186487 "Myelin transcription factor 1 like" Q9UL68 2 1789113-2331664 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Autism spectrum disorder, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 45.8;pituitary gland: 14.8" "Group enriched" "Detected in many" 4 "Excitatory neurons: 582.4;Inhibitory neurons: 635.5;Oligodendrocyte precursor cells: 265.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 45.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "SCLC-21H: 18.6;SH-SY5Y: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060245 Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA060245: AB_2732643" "unprognostic (9.90e-3)" "unprognostic (3.74e-1)" "unprognostic (1.30e-1)" "unprognostic (9.61e-3)" "unprognostic (7.17e-2)" "unprognostic (3.73e-2)" "unprognostic (2.44e-1)" "unprognostic (2.36e-2)" "unprognostic (3.21e-2)" "unprognostic (1.93e-2)" "unprognostic (2.46e-1)" "unprognostic (7.96e-2)" "unprognostic (1.21e-2)" "unprognostic (1.04e-2)" 0.0 1.4 7.8 0.2 14.1 0.1 0.0 4.2 45.8 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 17.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 14.8 0.1 0.0 0.1 0.1 5.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 18.6 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.1 7.8 14.1 4.2 45.8 17.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.1 6.4 6.1 16.6 0.0 1.8 0.5 0.0 0.0 46.7 0.5 0.4 4.5 0.0 3.1 1.8 2.1 0.1 0.2 0.1 0.0 0.0 5.0 0.4 0.1 1.3 0.0 0.0 582.4 0.0 0.2 1.3 0.0 0.2 6.3 0.1 0.7 0.4 0.1 117.8 635.5 0.0 0.0 0.6 0.8 4.7 0.0 0.8 0.0 18.7 0.0 1.5 0.0 265.4 11.1 0.1 0.0 1.5 0.1 0.4 0.0 0.2 1.5 7.4 6.6 1.5 0.4 50.0 31.4 0.0 1.0 0.3 0.9 0.1 0.0 0.6 NAP1L3 "MB20, MGC26312, NPL3" ENSG00000186310 "Nucleosome assembly protein 1 like 3" Q99457 X 93670930-93673578 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 103.4;retina: 40.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 41.8;Excitatory neurons: 27.9;Horizontal cells: 62.2;Inhibitory neurons: 57.1" "Cancer enhanced" "Detected in many" "glioma: 12.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.1" "Group enriched" "Detected in many" 25 "NK-cells: 3.1;T-cells: 4.1" "Cell line enhanced" "Detected in some" "AF22: 13.6;HAP1: 13.2;NTERA-2: 24.0;SuSa: 20.7;U-2197: 16.1" "Low region specificity" "Detected in all" HPA026075 Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA026075: AB_1854301" "unprognostic (7.18e-2)" "unprognostic (1.81e-2)" "unprognostic (9.26e-2)" "unprognostic (4.83e-4)" "unprognostic (3.06e-1)" "unprognostic (1.28e-2)" "unprognostic (5.10e-2)" "unprognostic (1.76e-1)" "unprognostic (3.31e-2)" "unprognostic (9.29e-2)" "unprognostic (2.75e-3)" "unprognostic (5.01e-2)" "unprognostic (2.75e-3)" "unprognostic (5.78e-3)" "unprognostic (1.19e-1)" "unprognostic (1.75e-1)" "unprognostic (5.23e-4)" 2.5 13.4 65.2 2.8 53.3 1.2 2.6 46.9 103.4 19.3 11.2 3.2 1.5 12.1 5.6 1.3 10.0 5.4 11.3 50.5 62.9 3.3 1.3 1.8 2.5 45.3 62.7 16.7 1.3 1.0 18.1 1.5 54.4 4.4 2.4 40.9 1.4 5.3 0.4 1.7 2.0 8.2 40.6 4.6 1.4 16.6 46.9 1.1 5.6 1.2 1.3 3.5 2.8 47.5 0.0 0.2 13.6 9.9 0.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 2.0 7.6 0.3 0.1 13.2 0.0 0.0 0.0 0.3 6.4 0.0 0.2 0.7 0.0 0.4 6.1 0.0 0.6 6.2 0.0 0.0 6.8 0.0 0.0 0.7 0.0 0.0 0.0 24.0 0.0 5.7 0.0 10.5 0.0 0.4 0.1 0.1 1.4 0.0 0.0 0.2 20.7 0.0 0.7 0.0 7.5 10.9 16.1 0.7 10.2 4.5 0.0 4.2 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.7 0.0 2.6 0.9 0.0 0.0 4.1 2.9 0.1 3.1 0.0 0.0 0.8 0.9 65.2 53.3 46.9 103.4 50.5 62.9 45.3 62.7 54.4 40.6 46.9 47.5 0.8 0.0 0.0 11.8 0.3 0.6 0.3 0.0 0.0 41.8 0.2 1.9 8.3 0.0 0.6 0.0 6.2 0.2 0.8 0.0 17.6 0.1 1.2 0.3 9.9 1.4 0.0 1.3 27.9 0.0 0.2 7.6 0.0 0.3 5.7 7.4 1.1 0.0 0.4 62.2 57.1 0.0 0.0 0.0 0.9 2.2 11.8 0.3 5.4 9.4 0.2 16.6 0.0 16.6 21.2 0.2 0.0 19.5 0.1 0.0 0.0 0.5 1.5 12.9 0.0 6.6 4.0 5.7 7.4 0.0 0.4 0.3 1.6 16.4 0.0 0.0 NDFIP2 "KIAA1165, N4wbp5a" ENSG00000102471 "Nedd4 family interacting protein 2" Q9NV92 13 79481124-79556075 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 342.7;Late spermatids: 290.4;Suprabasal keratinocytes: 367.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 12.1;eosinophil: 22.7;naive CD4 T-cell: 5.6" "Group enriched" "Detected in many" 16 "granulocytes: 22.7;T-cells: 5.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009160 Uncertain Supported Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA009160: AB_1079456" "unprognostic (2.56e-1)" "unprognostic (5.51e-3)" "unprognostic (1.95e-3)" "unprognostic (9.61e-2)" "unprognostic (2.60e-1)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.50e-1)" "unprognostic (5.53e-2)" "unprognostic (2.30e-1)" "unprognostic (3.12e-1)" "unprognostic (1.52e-2)" "unprognostic (2.63e-2)" "prognostic favorable (4.18e-5)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (6.47e-2)" "unprognostic (1.02e-1)" 13.9 19.2 17.0 11.4 20.9 2.6 22.7 10.0 25.2 15.5 7.0 42.7 52.7 10.1 22.5 54.4 17.1 20.1 26.0 27.1 8.1 45.9 46.3 17.7 13.0 10.1 7.3 7.0 31.8 29.6 6.4 31.9 12.3 22.7 47.0 21.7 21.4 15.6 30.9 71.3 64.3 9.1 10.6 11.7 25.9 18.1 9.2 16.0 19.3 19.9 19.6 35.6 25.2 21.5 134.6 22.6 23.2 29.4 27.7 50.3 43.6 48.5 66.9 50.1 83.0 49.9 146.1 5.6 32.6 64.0 28.5 178.2 20.5 84.9 75.3 69.7 57.1 6.2 66.5 27.1 50.5 106.2 17.8 40.4 109.3 33.4 52.7 55.8 24.1 10.4 27.5 10.0 56.8 19.3 8.7 24.1 17.1 109.7 22.7 0.5 45.7 25.2 123.1 76.7 23.3 33.4 54.9 52.4 40.0 37.8 43.8 88.2 20.4 16.0 20.4 31.1 32.8 37.6 44.2 21.1 65.6 0.5 65.6 12.1 0.0 22.7 3.2 0.0 2.7 0.2 2.8 2.6 0.0 0.6 5.6 3.1 0.1 0.8 0.0 0.2 3.2 2.4 17.0 20.9 10.0 25.2 27.1 8.1 10.1 7.3 12.3 10.6 9.2 21.5 17.5 41.7 28.9 26.4 4.4 342.7 137.0 180.6 118.4 30.9 32.7 18.8 29.4 57.2 93.2 47.8 6.2 112.6 6.9 161.0 23.5 85.6 271.2 51.5 17.2 22.0 69.4 4.2 189.0 72.2 152.7 33.2 31.1 49.8 88.2 11.5 20.7 69.2 14.4 16.8 44.2 88.1 95.6 17.0 23.5 290.4 17.4 4.0 33.8 27.2 2.7 22.8 5.2 42.3 100.3 101.7 96.7 12.8 13.8 105.6 204.3 104.6 112.6 15.5 13.1 22.2 24.0 56.5 45.1 102.2 367.7 109.7 24.9 35.2 73.3 145.5 NDNF "C4orf31, FLJ23191" ENSG00000173376 "Neuron derived neurotrophic factor" Q8TB73 4 121035613-121073021 "Disease related genes, Predicted secreted proteins" Neurogenesis "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 106.5;placenta: 60.1;retina: 57.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Bipolar cells: 69.8;Early spermatids: 217.1;Late spermatids: 221.7" "Cancer enriched" "Detected in many" 4 "lung cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 48.5;U-266/70: 20.8;U-266/84: 85.8" "Group enriched" "Detected in all" 4 "basal ganglia: 11.1;olfactory bulb: 34.0" "Low region specificity" "Detected in all" HPA048881 Supported Vesicles "Secreted in other tissues" NA NA "Cluster 19: Lung - Lung function" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA048881: " "unprognostic (2.84e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (3.94e-1)" "unprognostic (6.26e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (6.65e-4)" "unprognostic (2.18e-3)" "unprognostic (6.27e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.38e-3)" "unprognostic (1.20e-1)" "unprognostic (1.18e-4)" "unprognostic (1.74e-1)" 4.8 2.6 1.1 0.9 1.7 0.0 3.2 4.7 1.2 14.2 9.3 6.5 2.9 6.0 4.3 7.7 20.4 9.4 5.2 1.8 2.6 27.1 0.4 106.5 0.3 8.8 12.9 42.5 0.5 0.7 5.3 60.1 15.2 16.7 8.3 57.4 2.2 4.4 4.3 1.7 4.7 3.5 7.6 0.3 4.1 10.4 3.7 2.4 1.3 14.0 0.2 9.0 1.9 5.4 0.2 0.0 10.6 0.0 13.9 11.3 0.2 0.2 0.5 0.2 0.5 1.6 0.0 0.0 0.0 48.5 0.8 0.0 0.0 0.0 1.1 0.9 1.7 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.2 0.6 0.0 0.0 0.0 14.3 1.0 0.0 0.2 0.1 0.9 7.4 2.1 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 2.6 0.2 0.0 0.0 11.5 0.0 0.2 0.5 20.8 85.8 0.0 3.9 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 4.7 1.2 1.8 2.6 8.8 12.9 15.2 7.6 3.7 5.4 10.9 246.8 48.3 1.6 0.0 1.1 0.0 0.0 0.0 69.8 0.2 0.1 1.6 8.6 28.6 12.9 18.8 0.3 0.0 5.3 0.0 0.0 217.1 0.9 4.7 11.7 1.8 0.0 0.0 0.2 0.0 14.9 0.0 0.1 2.5 0.1 2.9 0.0 0.1 1.7 8.0 0.8 0.0 0.0 0.8 221.7 3.4 0.4 5.4 6.5 0.0 12.2 0.0 0.0 0.0 0.1 0.5 0.7 0.0 0.0 0.0 0.0 12.5 20.0 0.0 1.2 3.6 6.4 5.0 0.3 0.9 0.5 0.3 13.0 1.2 0.1 NELL2 NRP2 ENSG00000184613 "Neural EGFL like 2" Q99435 12 44508275-44921848 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.5;choroid plexus: 59.5;fallopian tube: 60.1;retina: 85.2" "Cell type enriched" "Detected in many" 6 "Excitatory neurons: 652.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 33.3" "Group enriched" "Detected in many" 15 "amygdala: 48.9;basal ganglia: 60.0;cerebral cortex: 105.5;hippocampal formation: 89.6;white matter: 42.0" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 70.4;naive CD8 T-cell: 111.1" "Lineage enriched" "Detected in many" 10 "T-cells: 111.1" "Cell line enhanced" "Detected in some" "AF22: 104.6;HEK 293: 27.5;NTERA-2: 41.2;SCLC-21H: 75.6;U-266/70: 27.5;U-266/84: 29.5;U-698: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035714, HPA035715" Uncertain Approved Vesicles "Secreted to blood" NA NA 6400000 "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA035714: AB_2674746, HPA035715: AB_10669602" "unprognostic (4.25e-3)" "unprognostic (4.27e-2)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (3.01e-2)" "unprognostic (7.18e-2)" "unprognostic (5.85e-2)" "unprognostic (2.59e-2)" "unprognostic (4.85e-2)" "unprognostic (2.80e-1)" "prognostic favorable (5.56e-4)" "unprognostic (1.19e-1)" "unprognostic (1.71e-5)" "unprognostic (8.45e-2)" "unprognostic (2.92e-1)" "unprognostic (3.60e-3)" "unprognostic (3.75e-2)" 4.6 16.9 48.9 10.9 60.0 7.3 1.9 1.3 105.5 23.1 59.5 2.0 26.3 2.2 0.4 1.2 60.1 1.9 0.4 89.6 4.5 1.2 1.0 5.0 20.7 0.0 0.0 0.8 0.9 0.2 34.6 0.3 0.0 27.2 2.1 85.2 1.4 2.0 0.3 13.4 15.3 2.8 0.0 6.2 2.9 3.0 0.8 8.7 6.5 0.6 15.7 4.1 4.2 42.0 0.3 0.1 104.6 3.5 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.4 0.0 8.3 12.4 0.0 0.0 0.2 25.3 0.2 0.0 0.0 27.5 0.4 8.7 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.1 1.6 0.2 0.4 0.0 0.4 0.2 0.4 41.2 0.0 14.0 0.2 12.7 0.2 0.0 0.0 75.6 1.8 0.0 0.4 0.0 1.3 0.1 0.7 0.0 0.4 3.8 0.1 2.1 27.5 29.5 40.3 0.2 0.2 0.4 0.2 0.2 0.0 5.0 0.1 24.9 0.2 30.3 52.9 0.1 0.1 70.4 111.1 0.5 11.0 0.1 0.1 0.4 26.7 48.9 60.0 1.3 105.5 89.6 4.5 0.0 0.0 0.0 0.0 0.8 42.0 0.3 0.0 1.3 48.0 1.0 1.1 0.0 0.0 5.7 35.4 0.4 0.6 0.5 2.8 6.2 0.0 33.3 0.1 2.5 5.8 0.0 0.0 0.4 0.7 0.8 0.7 0.0 0.0 652.4 0.2 0.3 3.7 0.0 0.3 0.0 49.4 0.0 0.0 0.1 1.7 108.4 0.9 0.0 0.0 1.5 1.0 0.0 0.4 0.0 18.7 1.3 7.9 1.0 74.4 16.5 0.4 0.4 0.4 0.5 0.3 18.5 0.2 21.9 58.3 0.0 4.1 4.6 1.9 4.2 0.2 1.1 0.1 23.4 0.1 2.9 0.1 NEURL2 "C20orf163, dJ337O18.6, FLJ30259, Ozz, Ozz-E3" ENSG00000124257 "Neuralized E3 ubiquitin protein ligase 2" Q9BR09 20 45888625-45891208 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 26.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 13.1;Proximal tubular cells: 17.3;Sertoli cells: 13.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 8.2;Hep G2: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043402, HPA059842" Approved Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA043402: AB_2678464, HPA059842: AB_2684139" "unprognostic (6.26e-2)" "unprognostic (1.77e-2)" "unprognostic (1.92e-1)" "unprognostic (1.48e-2)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.23e-3)" "unprognostic (1.07e-1)" "unprognostic (8.04e-2)" "unprognostic (2.90e-1)" "unprognostic (1.73e-3)" "unprognostic (5.58e-2)" "unprognostic (1.99e-2)" "unprognostic (6.94e-2)" "unprognostic (1.97e-1)" "unprognostic (8.12e-2)" "unprognostic (1.58e-1)" 14.1 9.1 1.8 2.6 3.0 1.3 6.9 4.0 3.1 5.2 4.5 7.3 4.3 6.2 3.0 2.6 7.4 2.9 8.9 2.0 2.1 26.7 8.2 3.9 1.5 2.4 2.3 9.4 4.4 3.8 4.1 3.1 2.3 4.4 2.2 4.2 5.5 2.7 18.1 4.7 6.5 4.0 2.0 5.9 5.0 2.5 2.1 7.6 5.8 8.9 1.3 7.9 4.3 3.2 0.9 0.7 1.9 1.6 3.1 1.3 1.6 1.2 1.4 1.3 0.6 8.2 5.2 1.0 1.7 0.9 2.3 2.7 1.6 0.0 0.8 0.6 1.4 0.6 6.4 8.5 3.9 0.6 1.4 2.9 1.1 1.3 0.5 2.0 1.0 1.6 0.8 2.1 0.7 3.2 1.0 0.6 0.9 0.5 2.9 1.7 1.4 0.5 0.8 0.7 4.2 3.0 1.7 4.1 5.2 0.4 3.1 1.7 2.0 1.5 1.3 1.2 1.2 6.0 1.3 0.2 1.7 0.8 1.4 0.0 0.6 1.8 0.4 0.3 0.2 2.8 0.7 0.6 0.2 1.0 1.5 1.3 0.2 1.0 0.2 0.3 0.5 0.3 1.8 3.0 4.0 3.1 2.0 2.1 2.4 2.3 2.3 2.0 2.1 3.2 1.7 0.0 0.0 2.0 2.3 0.1 2.1 1.0 2.8 3.5 2.2 3.4 5.7 0.0 0.4 0.0 4.2 0.7 0.5 5.0 7.9 3.2 2.8 0.8 2.3 2.7 3.0 1.3 1.4 2.0 0.9 3.3 3.1 0.9 0.0 7.8 5.7 5.7 13.1 0.0 2.3 2.3 0.0 5.1 0.3 8.6 5.3 1.2 0.0 1.0 1.5 2.5 2.1 2.0 1.4 2.9 0.7 3.8 2.2 2.3 6.7 17.3 0.5 3.4 13.1 3.2 6.1 0.0 0.3 1.8 1.1 0.5 0.7 11.0 2.1 1.7 NHLRC1 "bA204B7.2, EPM2B" ENSG00000187566 "NHL repeat containing E3 ubiquitin protein ligase 1" Q6VVB1 6 18120440-18122677 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" Transferase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 5.0;Exocrine glandular cells: 3.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 6.8;K-562: 6.1;SCLC-21H: 6.1" "Low region specificity" "Detected in all" HPA066030 Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA066030: " "unprognostic (1.61e-1)" "unprognostic (1.39e-1)" "unprognostic (7.95e-2)" "prognostic unfavorable (9.01e-4)" "unprognostic (6.95e-3)" "unprognostic (2.45e-1)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (2.39e-1)" "unprognostic (7.17e-2)" "unprognostic (5.07e-3)" "unprognostic (1.28e-1)" "unprognostic (2.32e-2)" "unprognostic (3.19e-1)" "unprognostic (2.33e-1)" "unprognostic (2.77e-2)" "prognostic favorable (5.30e-4)" 1.2 1.4 2.0 0.8 2.3 1.1 2.0 1.5 2.6 0.8 0.8 1.5 1.4 0.8 2.6 1.1 1.4 0.6 1.8 2.4 1.9 0.8 4.1 1.2 0.6 2.5 1.8 1.4 1.8 1.2 1.2 0.5 2.7 1.2 1.3 2.0 2.3 1.0 2.6 3.8 1.9 0.8 1.6 1.1 1.3 0.7 2.0 1.0 1.6 1.5 0.8 0.9 0.8 3.6 2.6 1.5 0.6 0.0 1.3 1.2 0.0 2.6 0.8 0.9 0.5 0.1 2.1 0.0 6.8 1.9 0.2 3.0 0.0 1.7 0.7 0.1 0.9 0.4 1.0 0.1 2.0 0.0 1.7 2.1 2.5 1.0 0.9 0.6 2.1 0.0 6.1 0.1 2.1 2.8 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.1 1.4 2.8 6.1 0.1 5.3 4.3 1.6 0.6 3.1 1.7 0.4 0.2 1.3 1.8 0.1 0.1 0.0 0.1 0.1 0.0 2.6 0.5 4.4 0.4 0.6 4.9 0.8 2.3 1.1 0.5 4.7 1.3 1.5 1.0 0.3 1.6 2.3 0.6 1.3 1.8 2.0 2.3 1.5 2.6 2.4 1.9 2.5 1.8 2.7 1.6 2.0 3.6 0.8 0.0 2.2 0.3 0.2 1.9 1.4 1.4 1.8 0.4 1.5 2.0 0.9 1.5 2.3 0.0 0.0 0.4 0.0 0.2 0.0 2.9 0.0 0.6 1.3 0.3 3.5 5.0 1.0 3.7 0.0 0.8 1.5 0.5 1.3 0.8 0.4 1.1 1.2 0.0 0.7 0.3 0.0 0.8 0.6 0.0 0.6 1.5 1.8 1.0 0.5 1.1 0.0 1.5 1.2 2.0 0.3 0.0 0.0 0.2 0.6 1.2 0.8 1.0 0.0 0.3 0.8 0.2 0.2 1.3 1.8 0.4 0.1 1.1 0.5 0.5 NIF3L1 "ALS2CR1, CALS-7, MDS015" ENSG00000196290 "NGG1 interacting factor 3 like 1" Q9GZT8 2 200889327-200903938 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 90.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036335, HPA036336, HPA061466" Supported Approved Vesicles NA NA 9800000 "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA036335: AB_10696654, HPA036336: AB_2675068, HPA061466: AB_2684532" "unprognostic (6.61e-2)" "unprognostic (1.16e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (9.52e-5)" "unprognostic (2.48e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.51e-6)" "unprognostic (1.94e-1)" "unprognostic (8.53e-3)" "unprognostic (6.75e-3)" "unprognostic (3.12e-2)" "unprognostic (2.65e-2)" "unprognostic (6.09e-2)" "unprognostic (1.16e-1)" "unprognostic (2.83e-1)" "unprognostic (6.04e-3)" "unprognostic (8.61e-2)" 13.2 19.2 14.1 15.2 15.8 11.0 24.3 15.7 23.8 17.7 13.7 21.8 16.5 15.9 26.3 16.7 22.5 13.2 21.5 14.9 14.8 24.3 22.9 15.6 26.5 15.3 13.8 21.4 15.5 27.0 9.7 19.1 16.2 17.2 28.0 32.7 19.8 19.8 23.5 21.6 15.7 19.1 15.6 18.1 20.1 18.5 14.1 26.5 19.4 30.6 32.4 17.1 12.7 17.5 39.5 42.1 66.9 41.3 29.8 37.1 45.9 42.6 45.4 88.6 71.3 66.1 44.7 31.8 40.2 36.5 64.1 42.7 96.8 56.0 94.6 42.4 90.8 47.4 73.6 70.9 27.0 56.8 31.3 31.7 52.3 58.6 55.8 39.9 29.9 65.6 70.2 31.4 52.7 51.4 69.9 71.1 79.1 44.7 73.5 41.1 37.1 61.6 46.8 40.6 42.3 49.5 36.6 36.8 51.9 94.4 36.5 50.5 15.6 42.2 39.8 38.3 39.0 28.4 58.3 68.4 41.4 45.6 41.6 70.1 23.0 30.7 27.8 34.9 29.1 31.4 31.8 35.3 28.8 23.7 35.4 29.1 7.8 33.6 31.1 29.8 32.0 24.2 14.1 15.8 15.7 23.8 14.9 14.8 15.3 13.8 16.2 15.6 14.1 17.5 6.0 0.0 7.0 2.6 11.7 3.7 7.7 43.1 12.5 90.5 6.9 9.3 13.9 10.0 26.5 5.5 14.6 34.3 8.0 7.5 15.6 20.3 16.2 10.2 9.3 7.0 1.8 23.2 6.2 18.2 35.6 9.8 9.7 7.8 9.5 12.7 6.8 9.3 17.2 18.5 5.7 10.5 26.4 7.3 2.2 6.5 16.1 9.5 5.4 5.6 17.2 18.8 8.2 2.5 5.7 13.2 9.2 19.2 23.9 6.3 10.1 21.3 24.9 27.4 6.6 7.2 14.5 30.9 24.4 12.9 8.2 22.6 10.0 11.1 11.4 6.2 NKG7 "GIG1, GMP-17" ENSG00000105374 "Natural killer cell granule protein 7" Q16617 19 51371606-51372701 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 602.6;lymphoid tissue: 154.6" "Group enriched" "Detected in many" 4 "dendritic cells: 3163.4;NK-cells: 7721.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 6827.0;MAIT T-cell: 2871.2;memory CD8 T-cell: 4295.0;naive CD8 T-cell: 3114.2;NK-cell: 4796.8" "Group enriched" "Detected in all" 44 "NK-cells: 4796.8;T-cells: 6827.0" "Group enriched" "Detected in some" 5 "NB-4: 180.8;THP-1: 54.5;U-937: 46.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071454 Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA071454: AB_2686399" "unprognostic (1.56e-2)" "unprognostic (1.05e-2)" "unprognostic (6.54e-2)" "prognostic favorable (7.42e-6)" "unprognostic (1.27e-2)" "unprognostic (3.25e-3)" "unprognostic (2.96e-3)" "unprognostic (2.14e-1)" "unprognostic (3.22e-3)" "unprognostic (3.89e-3)" "unprognostic (3.39e-1)" "unprognostic (9.93e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (7.62e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-2)" "unprognostic (6.44e-3)" 12.5 7.9 3.7 23.2 3.6 602.6 7.7 3.6 6.3 5.9 4.2 9.5 11.0 12.5 6.1 7.2 7.9 21.4 6.7 3.5 3.6 6.5 23.5 49.2 136.4 4.9 3.9 4.2 2.2 2.2 3.2 7.9 4.2 4.9 7.3 0.4 9.6 4.5 6.5 2.7 14.6 7.7 4.1 154.6 10.6 3.3 4.3 9.4 6.6 3.3 21.9 16.7 4.4 4.2 0.1 0.3 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.9 7.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.6 0.6 2.0 0.8 0.2 0.0 20.1 3.6 0.0 0.0 0.3 0.0 0.2 0.0 2.5 0.5 0.8 0.0 0.0 2.4 180.8 0.0 0.2 0.3 4.4 9.4 0.4 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.3 0.0 54.5 0.4 0.1 0.2 0.6 0.1 2.6 0.9 0.9 0.1 46.6 0.0 76.9 34.1 15.2 6827.0 131.7 2871.2 37.9 811.1 4295.0 87.1 15.4 261.0 3114.2 111.7 4796.8 104.8 67.1 17.5 4929.2 3.7 3.6 3.6 6.3 3.5 3.6 4.9 3.9 4.2 4.1 4.3 4.2 17.2 3.2 8.0 0.0 24.5 5.0 0.1 0.0 0.0 0.0 5.7 3.7 0.7 28.6 1.3 5.5 0.0 1.0 3163.4 1.9 3.9 1.0 0.2 2.7 3.6 7.1 0.0 186.5 0.0 0.0 0.8 5.2 17.3 4.2 24.1 0.2 55.3 9.9 15.0 0.0 0.0 0.5 0.0 132.9 10.2 0.3 0.0 55.5 17.8 1.0 49.4 0.0 7721.0 0.0 0.2 0.0 1.2 0.0 120.4 0.0 0.6 9.2 0.7 0.0 0.0 6.4 4.7 0.0 0.5 1.1 6.5 1.1 1321.5 0.0 1.1 0.1 NME6 "IPIA-ALPHA, NM23-H6" ENSG00000172113 "NME/NM23 nucleoside diphosphate kinase 6" O75414 3 48290722-48301685 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017909 Approved Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA017909: AB_1854530" "unprognostic (7.31e-3)" "unprognostic (1.87e-1)" "unprognostic (8.19e-3)" "unprognostic (2.09e-2)" "unprognostic (8.52e-2)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.17e-7)" "unprognostic (1.90e-1)" "unprognostic (1.56e-1)" "unprognostic (4.00e-3)" "unprognostic (1.32e-1)" "unprognostic (2.98e-1)" "prognostic favorable (3.18e-5)" "unprognostic (1.98e-2)" "unprognostic (1.57e-2)" "unprognostic (1.23e-1)" "unprognostic (9.50e-2)" 8.7 7.7 6.3 10.4 6.4 8.1 12.1 9.2 6.3 10.2 8.7 11.6 13.2 9.3 8.5 12.1 14.8 8.9 13.5 7.1 6.5 11.1 10.3 10.2 12.2 5.9 6.3 12.4 11.6 12.4 6.0 14.2 5.7 9.5 11.5 7.6 10.9 8.7 17.7 10.0 10.4 12.4 4.9 9.6 11.5 6.2 6.4 9.4 12.2 17.2 13.7 9.6 9.0 6.3 30.0 19.1 24.3 18.3 18.2 23.4 22.1 27.2 18.3 37.5 27.3 30.5 26.5 30.1 14.0 20.5 36.5 10.1 21.9 27.2 24.1 36.1 21.3 17.9 24.1 26.6 25.7 24.3 20.7 19.7 33.8 34.4 42.9 19.3 19.8 21.1 33.9 23.6 14.0 13.9 21.4 11.3 22.3 19.5 23.3 12.7 22.9 25.3 21.2 23.6 7.7 12.7 19.8 21.0 26.1 17.8 23.9 22.5 22.1 8.3 33.0 21.2 39.4 27.0 40.9 26.1 16.3 31.9 18.4 47.3 33.4 76.4 40.9 36.0 36.6 43.5 37.4 35.2 39.9 38.0 28.1 27.2 37.3 40.4 42.1 34.5 33.5 25.1 6.3 6.4 9.2 6.3 7.1 6.5 5.9 6.3 5.7 4.9 6.4 6.3 13.1 28.9 20.7 2.3 16.4 5.0 8.5 18.2 9.6 11.9 14.1 13.6 10.4 15.7 19.4 9.2 14.6 49.5 18.4 8.2 39.2 24.8 2.6 16.1 17.5 12.8 4.2 8.0 2.5 30.1 41.6 12.4 11.7 11.8 10.1 22.8 7.9 7.9 34.4 10.1 3.2 10.8 12.2 9.3 9.7 1.7 11.8 13.7 16.0 1.9 23.4 17.6 18.6 2.5 2.7 31.3 8.3 7.2 10.8 12.8 16.6 16.4 30.6 11.5 13.1 7.7 12.2 9.3 15.0 12.4 4.1 19.7 14.7 15.1 12.8 7.1 NOX3 GP91-3 ENSG00000074771 "NADPH oxidase 3" Q9HBY0 6 155395368-155455839 "Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "MCF7: 4.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA073837 Uncertain Vesicles NA NA "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA073837: " "unprognostic (3.42e-1)" 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NOXA1 "FLJ25475, NY-CO-31, SDCCAG31" ENSG00000188747 "NADPH oxidase activator 1" Q86UR1 9 137423350-137434406 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 37.5;Gastric mucus-secreting cells: 54.6;Paneth cells: 34.7;Proximal enterocytes: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CAPAN-2: 12.6;EFO-21: 11.3;MCF7: 19.8;T-47d: 18.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA044781 Uncertain Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA044781: AB_10960532" "unprognostic (2.15e-1)" "unprognostic (2.86e-1)" "unprognostic (1.55e-3)" "unprognostic (1.42e-3)" "unprognostic (4.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.79e-1)" "unprognostic (3.99e-3)" "unprognostic (2.72e-1)" "unprognostic (1.69e-1)" "unprognostic (5.45e-3)" "unprognostic (1.97e-3)" "prognostic favorable (2.65e-4)" "unprognostic (4.97e-3)" "unprognostic (2.67e-1)" "unprognostic (1.74e-1)" "unprognostic (3.10e-2)" 3.7 6.6 11.4 3.5 11.9 3.0 6.9 7.4 24.4 7.5 5.1 12.6 19.3 6.1 1.2 9.6 9.3 6.9 3.9 11.2 10.8 14.7 12.5 4.6 2.5 13.0 11.7 10.1 17.2 6.1 15.4 1.2 9.6 10.4 3.8 2.6 19.9 7.1 10.3 18.4 13.2 1.3 7.7 7.1 17.6 3.9 11.5 2.7 12.9 1.4 1.4 5.6 8.7 8.5 2.0 5.0 0.1 3.8 0.4 0.0 2.6 0.4 0.6 0.2 0.3 0.8 12.6 0.0 11.3 0.1 0.8 8.6 0.2 0.2 0.0 5.5 4.2 0.0 3.6 1.9 1.2 0.1 2.4 0.4 2.7 0.0 0.1 2.2 0.3 0.0 0.7 0.8 0.0 19.8 0.0 1.1 0.2 5.2 1.7 0.1 0.0 7.8 3.3 4.3 1.0 0.3 0.3 2.0 2.0 0.2 18.8 1.6 1.3 0.2 2.6 2.9 0.4 0.8 0.0 0.1 0.3 0.7 0.6 0.0 0.4 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.7 0.1 0.1 0.4 0.0 0.6 2.5 0.0 0.0 0.2 11.4 11.9 7.4 24.4 11.2 10.8 13.0 11.7 9.6 7.7 11.5 8.5 4.0 0.0 5.4 6.5 4.0 3.4 6.1 2.8 3.4 9.8 16.2 11.2 1.3 14.3 7.2 12.9 8.4 0.4 2.3 37.5 7.9 7.4 0.3 11.2 2.1 2.4 6.7 2.7 22.4 11.0 0.4 1.7 54.6 20.0 2.5 3.8 0.7 6.5 5.4 3.3 17.0 20.5 4.1 3.8 9.0 0.5 1.2 6.1 8.8 6.5 3.8 10.7 4.1 8.0 3.8 7.0 34.7 0.7 2.1 4.4 39.5 19.9 5.9 8.2 6.6 3.2 3.8 5.1 5.0 12.8 4.1 0.3 3.5 1.0 24.6 7.4 NREP "C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17" ENSG00000134986 "Neuronal regeneration related protein" Q16612 5 111662621-111997464 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 118.3;Excitatory neurons: 116.1;Theca cells: 150.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "myeloid DC: 24.6;NK-cell: 6.9;plasmacytoid DC: 25.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 425.3;SH-SY5Y: 461.8" "Region enriched" "Detected in all" 5 "cerebellum: 1766.0" "Region enhanced" "Detected in all" "cerebellum: 219.5" HPA000545 Approved Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA000545: AB_1845721" "unprognostic (2.85e-2)" "unprognostic (1.00e-2)" "unprognostic (2.30e-1)" "unprognostic (1.48e-3)" "unprognostic (4.37e-1)" "unprognostic (2.26e-1)" "unprognostic (8.16e-3)" "unprognostic (1.58e-1)" "unprognostic (6.45e-3)" "unprognostic (1.32e-1)" "unprognostic (3.76e-2)" "unprognostic (2.02e-1)" "unprognostic (4.44e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.84e-2)" "unprognostic (3.47e-3)" "unprognostic (5.76e-3)" 18.9 56.5 50.1 19.4 52.6 36.7 29.3 141.8 71.6 32.3 56.9 28.6 16.9 84.8 17.9 23.0 18.2 65.4 70.9 52.5 44.0 49.5 50.7 27.7 17.3 47.8 52.1 41.8 9.8 8.4 13.3 119.8 50.8 52.7 25.2 107.4 36.1 72.2 179.9 22.1 16.7 54.6 44.6 36.9 25.7 12.7 46.4 168.1 18.6 118.2 18.4 27.5 16.8 54.7 0.6 7.1 425.3 91.5 20.2 46.6 20.3 140.9 83.9 135.7 221.0 0.8 2.8 73.1 44.6 71.3 18.9 0.3 91.0 5.2 69.4 29.5 13.0 57.5 35.2 77.6 28.1 77.0 0.8 45.6 22.5 129.5 44.5 318.6 154.2 81.4 0.6 7.4 143.4 1.6 308.3 53.7 244.1 0.2 33.3 326.3 173.4 19.9 52.2 1.6 96.9 461.8 31.6 2.2 2.9 224.2 17.7 210.6 31.1 163.7 54.1 80.8 15.8 34.6 29.3 92.3 35.6 159.8 32.8 0.0 4.0 0.0 0.0 2.2 0.0 1.6 0.1 0.2 24.6 1.1 1.2 1.6 0.1 6.9 1.0 25.1 0.0 2.2 50.1 52.6 141.8 71.6 52.5 44.0 47.8 52.1 50.8 44.6 46.4 54.7 20.8 6.4 30.8 43.1 3.6 18.1 1.6 4.5 14.2 66.9 12.4 22.6 33.4 8.6 5.7 12.9 87.6 118.3 12.9 2.5 33.2 14.4 2.5 5.4 69.1 38.9 21.6 52.2 116.1 5.5 18.6 31.7 31.1 7.4 5.1 69.9 27.5 10.1 35.5 20.2 51.4 9.3 42.7 10.0 19.0 1.0 8.4 14.9 14.2 17.8 11.5 14.9 5.2 37.2 4.6 8.2 2.0 23.3 0.9 0.7 1.2 61.0 0.5 29.0 13.1 25.4 51.8 0.8 12.6 11.9 12.6 31.5 3.2 150.8 11.3 0.2 NRG3 ENSG00000185737 "Neuregulin 3" P56975 10 81875194-82987179 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.3;retina: 5.2" "Group enriched" "Detected in some" 18 "Astrocytes: 2921.6;Excitatory neurons: 3761.0;Inhibitory neurons: 3088.3;Oligodendrocyte precursor cells: 1175.2" "Cancer enhanced" "Detected in many" "melanoma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;SK-MEL-30: 2.7;U-2 OS: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075789 Uncertain Vesicles "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA075789: " "unprognostic (6.15e-3)" "unprognostic (2.43e-2)" "unprognostic (1.65e-5)" "unprognostic (1.89e-1)" "unprognostic (7.03e-4)" "unprognostic (1.85e-2)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" "unprognostic (9.33e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-1)" "unprognostic (3.75e-2)" "unprognostic (3.31e-4)" "unprognostic (1.04e-1)" "unprognostic (7.68e-3)" "unprognostic (7.27e-4)" 0.1 0.4 16.4 0.3 11.4 0.0 1.3 0.0 17.3 0.1 0.0 0.4 0.1 0.0 0.0 0.1 4.7 2.8 0.4 16.1 2.6 0.7 0.5 0.7 0.1 1.2 6.3 0.0 0.1 0.1 2.0 0.3 0.4 0.1 0.1 5.2 2.6 0.2 0.0 0.6 0.1 0.1 2.5 0.1 0.3 1.8 9.9 0.0 0.2 0.1 0.0 0.1 0.0 3.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 11.4 0.0 17.3 16.1 2.6 1.2 6.3 0.4 2.5 9.9 3.5 0.1 0.0 0.0 2921.6 0.1 0.0 0.0 0.0 0.0 15.9 0.7 0.6 0.8 2.8 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.9 31.4 0.0 0.0 0.7 0.0 0.0 3761.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 3088.3 0.0 0.0 0.0 0.0 12.8 0.6 0.1 0.0 148.0 0.0 6.7 0.0 1175.2 50.2 0.2 0.0 0.7 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 NSUN7 FLJ14001 ENSG00000179299 "NOP2/Sun RNA methyltransferase family member 7" Q8NE18 4 40749925-40811184 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 16.5" "Cell type enhanced" "Detected in many" "Early spermatids: 47.5;Late spermatids: 75.6;Respiratory ciliated cells: 36.4;Spermatocytes: 38.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.7" "Cell line enhanced" "Detected in some" "A-431: 2.6;CAPAN-2: 5.5;Karpas-707: 4.0;MCF7: 2.6;SuSa: 3.0;T-47d: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA020653 Uncertain Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA020653: AB_1848710" "unprognostic (2.32e-1)" "unprognostic (4.22e-1)" "unprognostic (4.77e-2)" "unprognostic (1.50e-1)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.63e-1)" "unprognostic (4.01e-3)" "unprognostic (4.37e-2)" "unprognostic (3.06e-1)" "unprognostic (2.24e-1)" "unprognostic (8.42e-2)" "prognostic favorable (2.76e-8)" "unprognostic (3.69e-2)" "unprognostic (1.15e-1)" "unprognostic (1.12e-1)" "unprognostic (1.04e-2)" 0.6 0.9 0.6 1.0 0.6 0.6 3.8 0.4 0.4 2.5 7.2 2.8 1.7 2.2 2.7 1.8 6.8 1.2 2.1 0.5 1.5 4.7 0.4 3.3 0.3 1.8 2.4 2.3 7.2 3.3 3.6 1.3 1.5 4.5 2.4 0.7 4.8 1.5 0.0 1.5 2.1 1.2 1.2 2.7 3.2 16.5 2.0 0.3 4.7 0.2 0.3 1.3 1.2 0.8 2.6 0.1 1.2 0.0 0.0 0.0 1.7 0.0 0.2 0.1 0.1 1.0 5.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 2.6 0.1 0.0 1.4 0.0 0.3 0.1 0.0 0.0 2.4 0.7 0.6 1.5 0.3 1.7 0.0 3.0 3.9 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.4 0.4 0.5 1.5 1.8 2.4 1.5 1.2 2.0 0.8 0.1 9.6 7.8 3.6 4.3 1.1 3.1 1.5 2.2 0.1 8.6 7.1 3.5 0.0 10.5 9.2 0.0 9.2 0.1 2.7 9.8 5.8 47.5 20.7 0.9 0.6 8.3 0.4 0.7 5.4 3.6 1.2 4.6 5.4 0.0 8.5 0.7 0.2 3.8 0.0 0.9 7.1 4.1 0.8 0.4 75.6 1.5 2.2 0.0 8.4 1.0 2.1 0.0 18.1 1.3 4.7 2.7 0.0 0.3 4.5 2.2 5.5 36.4 0.1 0.0 0.4 0.8 38.9 11.4 8.2 1.0 4.5 0.7 3.4 7.7 5.7 NTF3 NGF2 ENSG00000185652 "Neurotrophin 3" P20783 12 5432108-5521536 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 18.5;Basal prostatic cells: 36.6;Basal squamous epithelial cells: 89.4;Prostatic glandular cells: 20.5;Sertoli cells: 32.9;Smooth muscle cells: 24.0" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.2" "Group enriched" "Detected in some" 5 "cerebellum: 3.4;cerebral cortex: 1.3;hippocampal formation: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 11.4;BJ hTERT+ SV40 Large T+: 14.8;BJ hTERT+ SV40 Large T+ RasG12V: 19.7;HBF TERT88: 18.0;RT4: 8.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebellum: 4.7;cerebral cortex: 2.0;hippocampal formation: 2.2" HPA032001 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA032001: AB_2674106" "unprognostic (3.04e-2)" "unprognostic (7.46e-2)" "unprognostic (7.33e-3)" "unprognostic (4.66e-3)" "unprognostic (8.89e-2)" "unprognostic (1.08e-2)" "unprognostic (1.36e-3)" "unprognostic (7.68e-2)" "unprognostic (1.35e-1)" "unprognostic (2.14e-1)" "unprognostic (1.86e-1)" "unprognostic (2.20e-1)" "unprognostic (7.77e-4)" "unprognostic (4.02e-3)" "unprognostic (1.92e-1)" "unprognostic (8.06e-3)" "unprognostic (4.51e-3)" 4.2 1.8 0.2 0.7 0.4 0.0 2.7 3.4 1.3 6.6 0.2 1.8 1.9 1.9 2.0 3.4 2.9 1.8 3.1 1.2 0.3 2.6 7.7 1.6 0.3 0.4 0.2 11.1 0.2 0.1 1.0 1.9 0.3 3.6 1.0 0.1 3.1 2.4 1.8 3.2 2.5 0.9 0.3 4.5 2.5 0.8 0.1 0.4 0.9 1.0 0.4 4.6 7.0 0.2 1.9 0.0 6.7 0.0 0.0 0.0 0.0 4.5 11.4 14.8 19.7 0.1 0.2 0.0 6.7 7.3 0.0 2.4 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 4.5 4.7 8.5 0.3 0.0 0.0 0.1 0.0 3.9 0.0 0.0 0.0 0.0 3.1 0.2 0.0 0.2 0.1 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 3.4 1.3 1.2 0.3 0.4 0.2 0.3 0.3 0.1 0.2 1.0 0.0 0.0 0.0 0.0 18.5 36.6 0.7 89.4 0.0 0.2 10.3 0.9 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.2 0.2 1.4 0.0 0.0 0.1 0.0 0.1 6.1 0.0 0.1 0.0 0.0 5.0 2.1 0.0 0.0 1.2 0.1 0.0 0.0 2.1 0.1 8.4 0.3 7.2 3.7 0.0 0.0 0.0 0.0 0.0 0.0 1.1 10.9 0.0 20.5 0.2 0.0 0.8 0.0 32.9 6.8 24.0 0.5 0.8 5.0 3.3 0.1 0.5 0.5 0.2 6.9 NTS ENSG00000133636 Neurotensin P30990 12 85874295-85882992 "Predicted secreted proteins" Vasoactive "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 165.8" "Cell type enriched" "Detected in some" 13 "Intestinal goblet cells: 1683.2" "Cancer enhanced" "Detected in many" "lung cancer: 155.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SuSa: 205.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 154.3" "HPA026664, HPA071012" Enhanced Supported Vesicles "Secreted to digestive system" NA NA 1600000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "HPA026664: AB_2671936, HPA071012: " "unprognostic (3.63e-1)" "prognostic favorable (9.94e-5)" "unprognostic (8.18e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.99e-2)" "unprognostic (3.04e-1)" "unprognostic (7.62e-2)" "unprognostic (2.43e-1)" "unprognostic (1.53e-3)" "unprognostic (8.83e-2)" "unprognostic (1.74e-2)" "unprognostic (3.76e-2)" "unprognostic (1.30e-6)" "unprognostic (2.94e-2)" "unprognostic (2.25e-1)" "unprognostic (2.17e-1)" "unprognostic (7.48e-2)" 6.2 1.2 3.3 3.6 0.6 0.0 5.2 0.9 8.4 0.7 0.5 1.8 6.6 0.3 0.7 5.6 0.9 1.3 0.9 2.5 18.1 1.7 1.4 1.2 11.7 11.7 10.2 0.6 0.4 0.1 32.3 0.5 6.2 0.3 1.5 0.0 0.1 0.6 0.0 0.2 165.8 1.1 3.2 0.1 36.4 0.3 26.8 0.5 0.8 0.2 1.0 3.1 0.3 3.6 0.0 5.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 0.0 0.0 0.0 0.0 1.0 50.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 10.7 0.0 4.1 0.0 1.7 0.0 0.0 0.0 5.4 1.6 0.0 0.0 0.0 205.5 0.4 0.0 0.0 0.1 0.0 0.4 0.0 2.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.6 0.9 8.4 2.5 18.1 11.7 10.2 6.2 3.2 26.8 3.6 3.6 0.0 0.5 0.0 0.0 1.3 0.7 22.6 0.0 0.0 10.1 0.0 0.3 0.0 27.0 9.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.4 2.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 44.3 0.0 0.2 0.0 1.2 1683.2 2.0 0.3 2.6 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.5 15.0 0.0 0.0 2.5 120.8 0.0 3.5 0.0 0.0 0.0 0.9 0.8 0.1 1.2 2.3 0.1 1.3 0.0 8.1 60.4 OLFM3 NOE3 ENSG00000118733 "Olfactomedin 3" Q96PB7 1 101802560-101996926 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 12.0;retina: 7.4" "Group enriched" "Detected in some" 17 "Excitatory neurons: 653.3;Inhibitory neurons: 174.6" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "AF22: 5.7;HAP1: 3.9;HEL: 3.6;SCLC-21H: 2.2;SH-SY5Y: 2.2" "Region enhanced" "Detected in all" "cerebellum: 177.3" "Low region specificity" "Detected in all" HPA050297 Uncertain Vesicles "Secreted in brain" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA050297: " "unprognostic (4.19e-1)" "unprognostic (4.19e-4)" "unprognostic (1.26e-1)" "unprognostic (4.61e-2)" "unprognostic (2.93e-1)" "unprognostic (1.47e-2)" "unprognostic (3.58e-4)" "unprognostic (2.48e-1)" "unprognostic (5.68e-2)" 0.0 1.3 2.9 0.3 5.0 0.0 0.0 6.9 12.0 0.0 0.0 0.6 0.2 0.1 0.2 0.0 0.0 0.0 0.0 6.4 3.9 0.4 0.0 0.0 0.0 1.2 1.9 0.0 0.0 0.0 1.2 0.0 1.2 0.0 0.5 7.4 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.1 0.2 0.1 3.7 0.0 0.3 0.0 0.0 0.0 0.0 4.6 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 2.2 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 5.0 6.9 12.0 6.4 3.9 1.2 1.9 1.2 0.0 3.7 4.6 0.1 0.0 0.0 10.7 0.0 0.0 0.1 0.0 0.0 23.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 653.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 174.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 0.0 0.7 0.0 8.5 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 6.5 0.0 0.0 OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 136.6;Fibroblasts: 246.9;Leydig cells: 73.3;Theca cells: 126.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 577.3;ASC TERT1: 312.6;BJ hTERT+: 374.8;HSkMC: 581.6;LHCN-M2: 602.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" NA NA 3000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA027991: AB_2732440" "unprognostic (1.04e-1)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.80e-3)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "unprognostic (4.41e-3)" 85.6 42.6 5.7 24.9 7.4 0.9 89.7 7.2 12.4 170.6 8.2 71.9 15.1 124.7 42.6 26.6 96.3 95.0 56.6 5.4 6.7 34.1 36.3 55.4 12.0 9.8 7.7 177.4 35.2 9.9 17.9 111.8 8.6 42.9 34.5 0.2 16.7 73.8 10.3 37.6 32.3 94.6 9.2 9.9 48.4 9.3 9.7 8.9 21.8 38.2 14.9 71.1 98.8 11.2 0.0 19.7 9.7 0.1 577.3 312.6 0.6 77.1 374.8 26.5 85.3 25.2 0.2 0.0 4.1 222.4 0.2 0.0 3.2 0.3 4.0 0.0 0.0 0.0 0.1 19.3 149.6 0.2 0.0 581.6 0.0 37.2 0.5 10.7 2.1 0.0 0.0 0.1 602.3 0.3 0.2 0.4 45.8 0.0 0.7 0.1 142.6 0.3 0.0 0.0 0.3 5.4 0.1 0.2 10.5 143.3 224.6 0.9 1.8 14.9 27.6 5.9 0.0 0.2 0.1 0.0 7.3 0.0 94.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 7.4 7.2 12.4 5.4 6.7 9.8 7.7 8.6 9.2 9.7 11.2 13.6 0.0 3.7 0.0 0.4 13.0 0.2 0.0 0.6 0.0 2.1 2.9 1.4 4.3 0.8 1.8 0.0 6.8 1.1 0.2 0.0 0.8 2.9 6.2 136.6 9.5 6.0 0.0 0.0 0.0 4.9 246.9 5.6 3.5 1.3 0.3 45.7 0.5 33.3 0.0 0.0 0.6 0.0 5.9 22.7 1.7 73.3 15.5 12.4 16.9 0.6 0.0 0.0 0.0 0.1 0.3 0.1 33.1 0.2 0.7 0.0 0.5 0.0 0.1 0.0 44.8 28.0 0.3 0.4 1.2 11.5 12.4 2.6 126.1 0.2 0.2 OSBPL5 "KIAA1534, OBPH1, ORP5" ENSG00000021762 "Oxysterol binding protein like 5" Q9H0X9 11 3087107-3166739 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 34.6;Horizontal cells: 62.2;NK-cells: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 3.6;gdT-cell: 9.0;intermediate monocyte: 4.7;memory CD8 T-cell: 3.3;myeloid DC: 3.0;naive CD8 T-cell: 3.4;NK-cell: 11.0;non-classical monocyte: 11.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038335, HPA038712, HPA058727" Approved Enhanced Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA038335: AB_2675963, HPA038712: AB_10675949, HPA058727: AB_2683799" "unprognostic (6.02e-2)" "unprognostic (1.16e-1)" "unprognostic (1.68e-1)" "unprognostic (3.69e-2)" "unprognostic (8.22e-3)" "unprognostic (1.71e-1)" "unprognostic (1.25e-1)" "unprognostic (4.03e-3)" "unprognostic (1.29e-1)" "unprognostic (3.49e-3)" "unprognostic (2.16e-3)" "unprognostic (9.44e-2)" "unprognostic (2.78e-2)" "unprognostic (1.22e-1)" "unprognostic (6.50e-2)" "unprognostic (7.67e-2)" "unprognostic (2.60e-1)" 22.0 8.0 7.1 7.2 7.7 13.6 19.2 7.8 11.5 42.2 2.1 28.2 5.9 26.6 2.9 12.5 22.3 5.0 14.9 5.2 6.4 13.5 3.1 17.5 2.4 50.3 13.3 14.5 10.4 2.3 10.3 5.0 56.0 25.6 3.2 1.8 16.4 9.9 9.9 25.9 16.6 7.6 5.4 24.9 15.5 3.3 19.8 22.0 14.9 5.9 1.4 24.6 28.3 10.5 3.7 5.6 6.6 7.6 18.9 8.8 0.1 17.9 8.8 7.1 5.0 0.0 10.4 0.0 5.3 10.1 4.9 13.3 1.3 5.0 1.1 3.5 6.0 15.1 19.2 0.0 15.9 13.6 2.3 13.9 5.7 2.5 2.6 5.2 4.8 26.7 5.5 0.0 3.5 10.3 30.7 75.5 4.8 2.4 11.5 15.9 9.0 2.2 3.0 3.3 10.8 1.3 7.6 26.1 7.0 3.7 10.8 35.9 16.4 8.8 12.1 21.2 3.1 3.8 0.0 0.5 9.5 25.3 11.5 0.2 3.6 1.2 9.0 4.7 1.2 0.0 0.9 3.3 3.0 0.0 0.6 3.4 0.4 11.0 11.5 1.3 0.1 5.2 7.1 7.7 7.8 11.5 5.2 6.4 50.3 13.3 56.0 5.4 19.8 10.5 19.5 0.0 5.5 8.1 0.5 4.8 2.6 4.2 5.2 11.5 7.7 5.2 6.9 2.8 4.8 3.7 8.4 0.4 34.6 8.3 1.9 3.0 0.1 2.2 22.1 12.1 0.0 5.7 25.6 2.0 0.6 12.3 5.1 2.5 1.3 3.5 3.9 0.5 1.7 62.2 20.6 8.0 2.0 8.7 3.1 1.2 9.0 3.9 3.6 17.8 2.3 4.1 56.7 20.1 28.2 2.2 8.5 17.0 4.9 3.2 6.1 3.2 5.5 1.2 13.1 7.4 11.4 0.1 0.6 3.8 6.8 0.0 9.1 2.5 8.2 2.5 OXR1 TLDC3 ENSG00000164830 "Oxidation resistance 1" Q8N573 8 106270144-106752694 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 1458.0;Inhibitory neurons: 1366.9;Late spermatids: 405.5;Microglial cells: 496.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027375, HPA027380, HPA027395" Enhanced Approved Vesicles NA NA 12000 "Cluster 38: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA027375: AB_10600087, HPA027380: AB_10601569, HPA027395: AB_10601554" "unprognostic (8.16e-3)" "unprognostic (1.39e-1)" "unprognostic (5.52e-2)" "unprognostic (3.12e-1)" "unprognostic (4.84e-2)" "unprognostic (2.84e-2)" "unprognostic (1.17e-1)" "unprognostic (3.67e-1)" "unprognostic (2.82e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (6.59e-2)" "prognostic favorable (5.82e-5)" "unprognostic (1.89e-1)" "unprognostic (1.32e-1)" "unprognostic (2.58e-1)" "unprognostic (2.86e-1)" 28.7 57.7 19.2 11.1 27.8 18.6 29.0 14.0 50.3 30.6 0.0 20.1 14.2 27.7 54.5 28.7 22.4 22.1 30.5 25.7 4.3 29.7 38.3 20.0 14.4 19.2 6.4 27.0 17.1 23.9 12.2 17.0 21.3 21.1 21.7 79.5 48.6 47.6 52.1 27.4 12.2 21.7 1.8 19.5 27.3 56.1 10.7 22.2 21.3 59.6 16.4 23.7 17.9 22.2 29.5 11.0 32.3 6.5 41.2 51.4 15.0 23.7 28.3 21.6 27.5 9.7 35.6 29.6 26.8 25.6 13.2 20.4 18.5 21.2 37.3 24.9 20.0 39.8 15.3 18.0 25.5 12.8 22.8 30.3 32.1 23.7 34.9 30.0 24.7 24.2 20.3 106.5 24.6 26.2 38.3 17.3 4.2 43.5 19.4 9.9 25.7 55.7 24.0 36.8 19.4 6.0 10.5 7.3 25.8 14.1 34.1 21.2 18.4 24.6 17.1 22.6 15.6 19.7 13.3 12.1 29.2 3.7 30.9 38.1 9.3 17.8 3.9 17.6 6.5 11.4 6.7 6.2 11.2 7.9 16.0 7.1 4.7 11.0 19.4 7.9 5.2 7.8 19.2 27.8 14.0 50.3 25.7 4.3 19.2 6.4 21.3 1.8 10.7 22.2 54.9 67.3 25.5 125.0 47.1 67.6 57.2 42.6 60.9 89.8 36.7 33.5 58.2 15.7 37.3 35.0 58.4 32.6 44.1 44.3 33.2 16.6 231.2 75.3 32.1 41.8 27.5 19.5 1458.0 17.0 20.0 41.3 39.8 65.3 30.4 29.1 44.6 34.5 19.5 26.9 1366.9 28.2 34.6 33.0 41.4 405.5 34.2 36.3 24.9 496.5 41.1 55.6 22.6 294.0 142.6 23.6 24.9 48.9 73.7 60.4 16.5 16.4 53.5 125.8 19.7 46.4 41.6 140.4 51.6 56.7 75.6 71.1 26.5 33.5 26.4 86.1 PAIP2 PAIP2A ENSG00000120727 "Poly(A) binding protein interacting protein 2" Q9BPZ3 5 139341587-139369720 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 834.4;Late spermatids: 2779.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035945, CAB037212, HPA056766" Approved Supported Vesicles NA NA 21000 "Cluster 5: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB037212: AB_1841072, HPA035945: AB_10672996, HPA056766: AB_2683231" "unprognostic (1.07e-1)" "unprognostic (1.44e-1)" "unprognostic (1.19e-1)" "unprognostic (5.86e-2)" "unprognostic (7.40e-2)" "unprognostic (3.80e-3)" "unprognostic (7.70e-3)" "unprognostic (8.91e-2)" "unprognostic (4.64e-2)" "unprognostic (2.36e-2)" "unprognostic (2.67e-2)" "unprognostic (3.27e-1)" "unprognostic (2.01e-3)" "unprognostic (2.01e-1)" "unprognostic (2.21e-1)" "unprognostic (3.36e-1)" "unprognostic (6.92e-2)" 103.3 148.6 107.9 77.2 107.9 115.7 90.3 120.0 149.6 77.3 119.9 79.1 44.2 94.1 85.6 68.8 91.6 66.5 173.1 107.8 118.9 104.7 114.2 73.1 109.0 119.5 114.0 112.3 64.2 88.9 96.2 93.7 123.8 84.3 53.9 168.9 92.1 82.4 169.6 48.2 50.0 83.1 119.1 92.1 58.1 169.0 110.0 147.4 74.6 161.9 107.7 81.4 54.3 138.9 91.9 102.7 196.2 118.5 144.0 81.3 95.6 81.9 113.6 104.7 163.6 138.5 86.7 160.7 170.8 62.3 120.1 88.9 173.5 112.5 137.4 155.7 136.4 148.5 145.7 125.8 93.0 92.8 105.4 93.2 92.4 78.5 88.8 112.9 108.7 173.3 143.7 138.6 95.8 121.1 254.3 227.3 118.9 130.5 74.6 140.0 248.1 177.2 84.0 163.2 90.9 165.2 121.2 110.7 251.2 245.4 214.4 192.6 66.9 55.9 67.9 61.3 67.3 200.0 262.6 167.8 98.2 161.6 58.9 569.5 292.2 735.8 286.2 329.3 317.0 378.7 314.7 330.4 292.0 337.7 364.4 356.5 800.5 347.5 380.6 298.7 449.5 577.2 107.9 107.9 120.0 149.6 107.8 118.9 119.5 114.0 123.8 119.1 110.0 138.9 154.8 73.7 87.5 26.4 173.8 159.8 164.3 168.2 79.1 102.4 108.2 98.0 59.7 97.2 100.9 99.3 58.4 198.6 253.1 74.0 170.2 126.4 834.4 228.6 109.2 126.9 97.0 190.0 40.6 115.1 134.1 129.5 38.7 109.0 109.0 108.2 123.1 103.8 142.3 97.6 46.6 57.7 120.1 142.2 196.1 2779.9 160.9 170.6 135.2 29.0 239.2 158.5 247.2 29.7 59.9 122.5 64.7 155.3 146.8 232.8 62.1 256.2 149.4 93.6 170.9 87.7 180.3 432.3 238.1 57.0 208.3 479.7 191.3 145.8 59.5 178.3 PAK3 "bPAK, hPAK3, MRX30, MRX47" ENSG00000077264 "P21 (RAC1) activated kinase 3" O75914 X 110944285-111227361 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Allosteric enzyme, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 31.9;pancreas: 42.7;pituitary gland: 13.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 104.1;Excitatory neurons: 364.0;Inhibitory neurons: 323.5;Oligodendrocyte precursor cells: 165.9;Peritubular cells: 81.3" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 5 "T-cells: 1.0" "Cell line enhanced" "Detected in some" "EFO-21: 10.8;HAP1: 9.9;HDLM-2: 12.4;NTERA-2: 9.7;SCLC-21H: 12.4;SH-SY5Y: 7.7;U-2197: 7.6;U-251 MG: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044791, HPA060219" Approved Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA044791: , HPA060219: AB_2684223" "unprognostic (1.80e-2)" "unprognostic (1.54e-1)" "unprognostic (1.80e-2)" "unprognostic (3.27e-4)" "unprognostic (2.46e-1)" "unprognostic (5.63e-3)" "unprognostic (7.29e-2)" "unprognostic (3.23e-2)" "unprognostic (1.27e-2)" "unprognostic (3.01e-1)" "unprognostic (6.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.89e-4)" "unprognostic (5.71e-3)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-2)" 1.0 5.2 16.9 1.6 16.2 0.1 5.2 0.0 17.6 2.3 0.0 0.7 0.2 5.4 5.8 0.7 2.5 1.6 0.3 17.8 31.9 0.7 0.2 0.9 1.7 1.6 0.0 6.2 42.7 0.1 13.7 0.6 6.0 3.4 0.7 7.0 2.2 4.8 1.6 1.3 0.5 4.7 0.4 2.0 2.0 2.6 13.2 0.6 6.2 0.4 0.8 0.9 0.7 2.8 0.0 0.7 1.4 0.0 0.0 0.0 0.0 0.3 0.4 1.1 0.0 0.0 0.0 0.0 10.8 1.2 1.6 0.0 9.9 0.6 1.3 12.4 0.4 0.0 1.3 0.0 0.0 0.0 0.4 0.3 0.0 0.1 2.2 5.7 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.2 9.7 0.0 2.2 0.1 4.3 0.0 0.8 0.0 12.4 7.7 0.0 0.4 0.0 6.6 0.0 0.0 0.0 0.7 4.7 7.6 13.6 0.1 0.1 0.1 1.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.9 16.2 0.0 17.6 17.8 31.9 1.6 0.0 6.0 0.4 13.2 2.8 0.9 3.2 1.1 16.0 0.6 0.3 13.3 0.2 0.0 104.1 6.9 10.4 1.0 20.0 0.7 0.0 0.0 0.3 0.2 0.2 0.0 4.7 4.4 1.0 10.8 2.3 3.6 0.0 364.0 13.1 0.4 10.3 10.2 1.7 1.3 21.9 1.4 0.2 0.2 6.7 323.5 0.3 0.0 0.3 5.7 7.0 34.2 1.1 0.0 17.8 0.7 27.5 1.0 165.9 12.0 5.3 0.0 81.3 1.0 1.7 0.0 0.6 0.0 6.0 0.0 1.6 7.8 1.4 1.4 0.3 1.1 6.7 2.4 29.2 0.3 0.9 PAQR4 FLJ30002 ENSG00000162073 "Progestin and adipoQ receptor family member 4" Q8N4S7 16 2969270-2973484 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 124.5;retina: 63.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 58.4;Oligodendrocytes: 62.0;Rod photoreceptor cells: 153.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 3.6" "Lineage enriched" "Detected in single" 9 "monocytes: 3.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068394 Approved Vesicles NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles "HPA068394: AB_2685980" "unprognostic (1.93e-1)" "unprognostic (2.75e-1)" "unprognostic (6.73e-2)" "unprognostic (1.30e-3)" "unprognostic (8.39e-2)" "unprognostic (3.00e-2)" "prognostic unfavorable (6.86e-4)" "unprognostic (2.62e-2)" "unprognostic (7.59e-2)" "unprognostic (9.65e-3)" "unprognostic (5.21e-2)" "unprognostic (8.59e-2)" "prognostic unfavorable (3.01e-6)" "prognostic favorable (1.70e-4)" "unprognostic (1.36e-1)" "unprognostic (3.79e-2)" "unprognostic (6.06e-3)" 4.3 8.1 54.4 6.9 80.8 15.7 4.3 80.0 65.3 3.6 32.7 6.5 6.2 2.3 0.5 11.3 3.7 6.9 9.3 55.1 56.4 3.9 3.4 7.9 8.7 93.0 77.4 0.7 11.9 38.4 2.1 2.6 85.9 11.8 5.6 63.7 22.7 1.4 17.6 16.1 6.3 3.5 68.1 7.9 10.5 3.2 74.6 11.0 3.3 27.9 10.3 2.5 4.6 124.5 36.9 30.9 34.4 49.5 5.6 10.0 11.3 13.9 16.6 24.9 23.5 18.8 38.3 36.8 18.3 16.1 17.5 50.8 36.1 21.7 10.4 38.8 16.3 11.5 63.6 25.4 0.6 24.1 39.2 2.4 11.3 13.5 3.5 12.6 16.7 30.7 22.5 95.6 21.7 73.8 35.1 25.8 29.1 55.3 21.6 69.5 45.0 117.6 17.5 12.4 77.3 36.0 51.2 48.5 37.3 4.6 51.6 37.2 10.3 43.0 26.3 20.0 19.8 42.2 30.7 49.3 19.1 32.4 48.4 0.0 0.4 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 3.6 0.2 0.0 0.3 54.4 80.8 80.0 65.3 55.1 56.4 93.0 77.4 85.9 68.1 74.6 124.5 4.8 0.0 0.0 13.4 2.0 3.1 1.6 2.6 2.2 14.9 5.2 5.2 1.1 12.8 7.8 0.0 58.4 2.2 2.0 5.1 0.0 5.2 0.8 3.0 1.5 4.5 4.2 12.6 8.9 11.3 8.9 2.0 2.6 5.2 2.5 4.6 3.9 0.3 13.3 6.7 4.5 5.5 6.1 7.6 4.6 3.6 0.6 7.2 5.4 2.8 2.2 27.8 2.1 4.5 62.0 9.5 2.5 0.0 5.5 5.0 2.2 1.0 11.0 153.4 0.0 0.3 3.5 1.5 6.3 4.1 5.1 0.5 1.8 1.0 10.9 1.0 PAQR5 "FLJ20190, MPRG" ENSG00000137819 "Progestin and adipoQ receptor family member 5" Q9NXK6 15 69298912-69407780 "Predicted membrane proteins" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 52.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;Distal tubular cells: 46.9;Early spermatids: 38.2;granulocytes: 67.2;Late spermatids: 123.0;Proximal tubular cells: 42.3" "Cancer enhanced" "Detected in many" "renal cancer: 8.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 1.1" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "A549: 38.1;CAPAN-2: 46.4;fHDF/TERT166: 33.1;HMC-1: 79.8;U-87 MG: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076729 Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA076729: AB_2686813" "unprognostic (4.47e-2)" "unprognostic (3.11e-2)" "unprognostic (1.46e-1)" "unprognostic (4.05e-4)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (3.58e-3)" "unprognostic (6.12e-3)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (2.00e-1)" "prognostic favorable (1.47e-14)" "unprognostic (5.64e-2)" "unprognostic (1.73e-1)" "unprognostic (4.16e-4)" "unprognostic (4.94e-2)" 0.6 16.0 3.5 2.6 2.8 1.2 1.2 2.7 3.0 1.7 12.0 19.0 2.3 1.0 0.2 12.4 0.9 2.0 0.8 3.1 2.8 52.9 1.1 9.1 0.3 3.4 3.1 0.6 5.1 11.3 0.8 1.6 4.0 0.6 16.2 1.9 1.8 3.7 0.2 4.9 8.0 0.9 2.8 0.4 7.7 2.4 4.4 0.2 0.8 0.2 2.1 3.6 2.9 2.9 11.7 38.1 0.8 0.8 1.6 4.2 0.3 3.7 22.2 4.3 9.1 2.2 46.4 0.1 5.9 33.1 3.7 0.7 10.9 0.6 7.4 0.1 1.7 6.9 5.6 0.8 2.9 0.2 79.8 2.2 1.7 19.4 20.7 5.5 0.0 0.2 0.1 0.7 18.4 1.6 0.2 0.2 2.6 6.1 3.2 0.1 0.6 2.2 16.6 0.9 3.3 0.7 6.0 2.3 3.1 2.1 1.0 2.8 0.6 13.1 4.2 1.1 0.4 0.2 0.3 0.1 33.1 0.1 3.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.5 2.8 2.7 3.0 3.1 2.8 3.4 3.1 4.0 2.8 4.4 2.9 0.1 12.8 21.0 1.0 0.5 0.9 1.3 0.4 1.2 0.7 1.3 0.8 0.7 32.9 0.9 20.2 0.0 0.0 0.0 31.1 46.9 19.0 38.2 0.7 0.1 1.9 0.0 0.0 0.5 0.4 0.0 2.8 2.0 1.5 67.2 2.2 0.0 0.0 3.7 0.0 0.7 4.8 0.0 0.3 0.7 123.0 0.9 1.8 0.0 20.6 0.0 5.9 0.0 1.0 0.5 2.6 6.9 1.2 0.0 1.4 26.8 42.3 0.8 0.1 6.6 0.1 0.6 0.5 0.5 15.1 1.8 0.1 0.4 19.6 13.7 0.8 PBLD "FLJ14767, MAWBP, MAWDBP" ENSG00000108187 "Phenazine biosynthesis like protein domain containing" P30039 10 68282660-68333049 "Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 171.5;kidney: 270.0;liver: 335.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 97.5;Distal tubular cells: 109.5;Hepatocytes: 216.9;Proximal enterocytes: 380.2;Proximal tubular cells: 426.5" "Cancer enhanced" "Detected in all" "liver cancer: 16.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA038035, HPA038036" Enhanced Approved Vesicles NA NA 1100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA038035: AB_10672470, HPA038036: AB_10675625" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (6.14e-2)" "unprognostic (8.83e-3)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" "prognostic favorable (1.44e-4)" "unprognostic (8.25e-2)" "unprognostic (3.62e-2)" "unprognostic (3.36e-3)" "unprognostic (1.19e-1)" "unprognostic (6.26e-3)" "unprognostic (3.40e-2)" "unprognostic (1.17e-1)" "unprognostic (2.07e-2)" "unprognostic (8.28e-2)" "unprognostic (6.68e-2)" 8.9 11.2 2.9 8.4 5.5 9.3 4.5 5.3 5.3 3.9 4.2 33.2 171.5 5.9 3.8 3.4 7.2 9.4 6.2 3.0 4.6 270.0 335.2 3.9 5.5 4.9 4.1 3.6 63.0 5.6 2.3 4.2 4.2 5.6 27.6 8.7 4.5 5.1 5.6 5.6 146.4 5.0 3.0 4.6 54.8 3.8 4.4 2.1 5.5 3.1 2.2 5.4 2.1 8.9 3.8 7.5 7.1 4.9 6.4 3.6 3.3 15.1 9.5 5.6 5.8 6.9 9.5 4.2 5.6 10.6 2.3 5.8 3.3 3.9 4.8 2.0 5.4 3.3 9.3 6.4 3.0 5.0 3.3 6.4 4.0 3.4 4.2 10.1 3.5 4.0 3.1 9.2 8.9 5.9 4.7 8.7 2.1 3.0 3.2 8.0 9.4 7.1 11.3 5.4 4.1 5.5 10.1 5.8 7.0 2.0 20.0 5.9 10.9 5.5 3.9 2.7 2.5 5.5 4.3 6.3 6.6 2.7 1.4 2.6 2.8 1.5 0.4 1.4 0.8 0.8 0.6 0.4 2.8 0.6 1.1 0.7 3.3 1.8 0.9 1.2 1.1 1.2 2.9 5.5 5.3 5.3 3.0 4.6 4.9 4.1 4.2 3.0 4.4 8.9 1.6 3.2 4.2 3.6 4.5 1.9 1.7 2.2 1.2 5.0 6.2 2.8 3.5 24.3 4.3 55.2 10.4 3.9 3.7 97.5 109.5 8.8 1.2 17.9 5.7 3.4 7.2 6.6 1.8 31.8 2.0 3.2 33.1 6.5 1.3 8.2 6.4 216.9 3.1 10.1 2.8 42.6 2.0 10.4 4.4 0.4 4.1 5.5 1.8 3.7 5.0 5.5 3.1 3.0 7.5 12.5 46.4 3.0 1.5 2.0 380.2 426.5 12.9 17.2 0.0 2.0 6.6 1.6 1.4 1.8 0.6 3.1 2.8 9.6 57.3 3.0 PBX4 ENSG00000105717 "PBX homeobox 4" Q9BYU1 19 19561707-19618693 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.1;thyroid gland: 2.3" "Cell type enhanced" "Detected in many" "dendritic cells: 14.5;Gastric mucus-secreting cells: 17.3;Plasma cells: 18.8;Spermatocytes: 26.6;T-cells: 50.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "gdT-cell: 1.7;MAIT T-cell: 1.7;memory CD4 T-cell: 1.2;memory CD8 T-cell: 1.9;naive CD4 T-cell: 1.2;naive CD8 T-cell: 1.0;T-reg: 3.1" "Lineage enriched" "Detected in single" 12 "T-cells: 3.1" "Cell line enhanced" "Detected in some" "A-431: 2.5;RT4: 3.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049859, HPA056469" Enhanced Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA049859: AB_2680918, HPA056469: AB_2797256" "unprognostic (5.36e-3)" "prognostic favorable (8.69e-6)" "unprognostic (9.39e-3)" "unprognostic (1.03e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-4)" "unprognostic (2.87e-2)" "unprognostic (1.18e-1)" "unprognostic (1.26e-1)" "unprognostic (3.86e-2)" "unprognostic (3.17e-1)" "unprognostic (1.13e-2)" "unprognostic (1.44e-6)" "unprognostic (2.20e-2)" "unprognostic (1.45e-1)" "unprognostic (5.89e-2)" "prognostic favorable (5.94e-7)" 0.2 0.0 0.6 0.4 0.6 0.4 0.2 0.3 0.8 0.1 0.3 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.6 0.6 0.1 0.0 0.3 1.2 0.5 0.5 0.2 0.0 0.1 0.3 0.2 0.5 0.1 0.1 0.0 0.1 0.1 0.0 0.4 0.4 0.0 0.4 0.3 0.4 2.1 1.0 1.0 2.3 0.0 0.6 0.1 0.1 0.5 2.5 0.1 1.0 0.0 0.2 0.0 1.7 0.0 0.8 1.1 0.8 0.0 1.1 0.3 0.4 0.6 0.9 1.1 1.4 0.0 0.3 0.1 0.5 0.0 0.4 0.0 0.1 0.0 0.4 0.2 0.0 0.3 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.5 1.0 0.7 0.2 1.8 1.9 0.5 0.0 0.0 0.8 3.2 0.8 1.1 1.1 0.1 0.8 0.1 0.4 0.1 0.0 0.0 0.5 1.5 0.3 0.2 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 1.7 0.2 1.2 1.9 0.0 0.0 1.2 1.0 0.2 0.0 0.0 0.0 3.1 0.5 0.6 0.6 0.3 0.8 0.6 0.6 0.5 0.5 0.5 0.4 1.0 0.5 0.7 0.0 4.1 9.8 8.7 4.8 2.6 1.3 1.8 0.6 1.1 1.8 0.4 1.5 1.6 0.0 0.0 0.0 14.5 1.1 1.9 0.7 3.1 8.3 1.1 0.4 0.0 0.8 5.0 0.0 1.1 3.4 17.3 3.5 0.0 1.2 0.4 0.0 0.4 0.0 7.3 2.9 0.0 0.3 3.8 1.5 0.3 1.6 1.8 1.0 1.5 1.4 6.2 1.5 1.4 2.4 0.1 0.7 18.8 2.6 0.2 0.0 5.4 0.1 6.6 1.4 1.4 26.6 10.7 0.7 2.6 0.0 50.4 0.5 0.7 3.1 PCDHA6 "CNR2, CNRS2, CRNR2, PCDH-ALPHA6" ENSG00000081842 "Protocadherin alpha 6" Q9UN73 5 140827958-141012347 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.0;EFO-21: 8.4;hTERT-RPE1: 2.2;U-2 OS: 3.4;WM-115: 5.2" "Low region specificity" "Detected in many" "HPA059326, HPA078110" Enhanced Approved Vesicles "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 38: EFO-21 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA059326: AB_2683980, HPA078110: AB_2732371" "unprognostic (1.15e-1)" "unprognostic (7.00e-2)" "unprognostic (5.07e-1)" "unprognostic (2.79e-1)" "unprognostic (4.39e-1)" "unprognostic (1.86e-1)" "unprognostic (7.18e-4)" "unprognostic (4.23e-3)" "unprognostic (8.38e-2)" "unprognostic (2.55e-1)" "unprognostic (1.23e-3)" "unprognostic (3.44e-1)" "unprognostic (1.03e-2)" "unprognostic (2.66e-3)" "unprognostic (2.56e-1)" "unprognostic (5.66e-3)" "unprognostic (3.55e-2)" 0.2 0.3 0.8 0.1 0.9 0.0 0.3 4.1 1.1 0.4 0.0 0.1 0.2 0.6 0.3 0.0 0.3 0.3 0.1 1.0 0.7 0.4 0.0 0.2 0.1 0.4 0.3 0.4 1.0 1.5 1.5 0.0 0.5 0.2 0.0 1.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.0 0.1 2.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.5 1.0 0.1 0.4 0.0 1.3 0.0 3.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 4.1 1.1 1.0 0.7 0.4 0.3 0.5 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHB14 PCDH-BETA14 ENSG00000120327 "Protocadherin beta 14" Q9Y5E9 5 141223343-141227759 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 15.1;Early spermatids: 8.1;Horizontal cells: 13.5;Peritubular cells: 8.6;Spermatocytes: 8.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 14.4;SiHa: 12.0;U-2197: 8.5" "Low region specificity" "Detected in all" "HPA007692, HPA045248" Uncertain Approved Vesicles NA NA 39000 "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA007692: AB_2667896, HPA045248: AB_10959599" "unprognostic (2.57e-3)" "unprognostic (1.96e-1)" "unprognostic (1.34e-1)" "unprognostic (8.97e-2)" "unprognostic (2.03e-2)" "unprognostic (6.64e-2)" "unprognostic (2.11e-2)" "unprognostic (2.38e-2)" "unprognostic (6.60e-2)" "unprognostic (2.57e-2)" "unprognostic (1.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (6.09e-4)" "unprognostic (2.58e-1)" "unprognostic (3.12e-2)" "unprognostic (3.77e-2)" "unprognostic (3.90e-2)" 3.1 2.8 2.3 0.8 3.2 0.1 3.5 2.1 4.0 6.0 0.0 4.6 0.3 7.0 2.4 2.0 4.3 1.9 4.4 2.6 1.3 2.1 1.2 3.0 0.4 1.5 2.3 4.7 4.0 3.6 6.2 1.1 0.7 3.1 0.9 2.3 3.6 1.9 1.6 4.4 1.6 2.6 1.6 2.0 1.9 2.5 3.1 0.4 2.2 1.5 0.3 3.5 3.5 3.3 0.0 0.0 3.3 6.3 5.4 6.4 0.4 0.5 5.5 0.5 1.7 0.1 1.0 0.3 4.5 1.5 2.9 0.3 0.7 1.0 0.5 0.0 0.1 0.0 1.3 0.1 0.2 0.3 0.2 1.2 4.7 0.1 0.2 4.8 0.6 0.2 0.0 5.8 2.3 0.5 0.4 0.0 0.4 0.0 1.1 3.8 4.1 0.0 0.1 0.2 7.6 14.4 12.0 0.3 1.3 0.5 6.1 0.5 1.7 2.2 1.9 8.5 2.2 0.0 0.1 0.1 4.5 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.2 2.1 4.0 2.6 1.3 1.5 2.3 0.7 1.6 3.1 3.3 4.1 0.0 4.8 0.0 0.0 0.4 1.1 3.1 0.0 15.1 1.6 2.4 3.3 0.0 3.1 1.8 0.0 0.0 0.2 0.3 0.0 0.9 8.1 0.8 6.3 3.9 3.5 0.0 0.0 2.4 0.0 5.0 0.0 0.9 0.0 1.3 3.3 1.3 0.1 13.5 0.0 0.6 4.1 0.0 0.7 2.1 3.4 0.3 0.0 0.0 0.0 6.8 0.0 0.0 0.0 2.2 0.5 8.6 0.0 0.5 0.0 0.8 0.6 1.3 0.0 6.3 3.9 8.0 0.1 0.7 2.8 0.0 0.2 2.5 0.3 0.7 PCDHB3 PCDH-BETA3 ENSG00000113205 "Protocadherin beta 3" Q9Y5E6 5 141100473-141103827 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.8;Cone photoreceptor cells: 2.1;Endometrial stromal cells: 2.6;Horizontal cells: 8.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 11.3;HAP1: 3.5;SH-SY5Y: 15.2;U-138 MG: 5.3" "Low region specificity" "Detected in all" HPA050296 Uncertain Supported Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050296: AB_2681078" "unprognostic (2.72e-2)" "unprognostic (7.47e-4)" "unprognostic (1.22e-1)" "unprognostic (1.95e-4)" "unprognostic (9.34e-3)" "unprognostic (3.42e-2)" "unprognostic (2.29e-2)" "unprognostic (3.17e-1)" "unprognostic (1.37e-1)" "unprognostic (3.34e-1)" "unprognostic (8.52e-3)" "unprognostic (3.45e-2)" "unprognostic (1.82e-2)" "unprognostic (2.37e-3)" "unprognostic (1.24e-1)" "unprognostic (1.82e-2)" "unprognostic (5.18e-4)" 1.8 1.2 0.4 0.7 1.1 0.0 1.7 0.6 1.5 1.2 0.0 0.9 0.3 1.5 0.7 0.3 0.9 0.8 1.1 1.0 0.2 1.1 0.1 1.1 0.1 0.3 0.5 1.6 1.2 1.7 1.8 0.4 0.1 1.4 0.5 1.0 0.7 0.5 0.7 0.7 0.5 1.0 0.2 0.4 0.5 3.6 0.6 0.0 0.7 0.9 0.1 0.8 0.9 0.8 0.0 0.0 1.1 3.1 1.9 0.3 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.2 1.7 0.0 3.5 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.3 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.6 15.2 0.0 0.1 0.0 0.5 1.9 0.1 0.0 5.3 0.7 0.5 0.3 0.3 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.6 1.5 1.0 0.2 0.3 0.5 0.1 0.2 0.6 0.8 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.9 0.8 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.9 0.3 0.8 0.4 2.6 1.1 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.2 0.0 0.0 1.8 0.0 0.0 8.4 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 1.8 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.5 0.0 0.1 0.0 0.3 0.0 1.7 1.1 1.8 0.7 0.1 0.3 0.0 0.0 0.4 0.0 0.3 PCSK1N "BigLEN, PEN, proSAAS, SAAS, SCG8, SgVIII" ENSG00000102109 "Proprotein convertase subtilisin/kexin type 1 inhibitor" Q9UHG2 X 48831096-48835610 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 642.6;pituitary gland: 1243.7" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 3045.7;Horizontal cells: 437.4;Paneth cells: 628.8;Proximal tubular cells: 1601.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 2.4;memory CD4 T-cell: 5.0;memory CD8 T-cell: 4.9;naive CD4 T-cell: 2.0;naive CD8 T-cell: 6.4;T-reg: 1.8" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Cell line enhanced" "Detected in many" "HEK 293: 58.9;PC-3: 148.5;SCLC-21H: 58.2;SH-SY5Y: 53.8;SiHa: 52.1;U-266/84: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003925, HPA064734" Enhanced Supported Approved Vesicles "Secreted to blood" NA NA 3300000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA003925: AB_1079582, HPA064734: AB_2685339" "unprognostic (2.44e-3)" "unprognostic (5.86e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (3.36e-1)" "unprognostic (4.76e-3)" "unprognostic (1.49e-2)" "unprognostic (3.34e-1)" "unprognostic (5.63e-2)" "unprognostic (3.55e-1)" "unprognostic (1.50e-3)" "unprognostic (2.79e-3)" "prognostic favorable (1.36e-4)" "unprognostic (3.34e-2)" "unprognostic (2.91e-2)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" 2.2 29.5 177.1 0.5 135.6 0.0 2.0 21.6 212.8 18.2 118.8 19.2 9.6 34.1 2.9 0.9 6.9 0.2 16.0 105.6 642.6 152.1 1.3 2.9 0.1 290.3 257.1 2.3 54.0 11.1 1243.7 0.2 193.0 14.4 0.5 2.5 6.7 0.8 0.8 8.8 13.7 0.6 95.5 1.1 21.9 19.7 264.9 0.0 3.3 0.0 0.0 1.2 6.5 51.8 0.1 5.4 0.2 14.9 0.6 0.0 0.4 0.0 0.0 0.0 0.0 5.3 0.1 0.0 10.4 0.0 4.2 0.8 0.0 1.1 0.0 0.0 58.9 0.0 0.0 9.3 0.0 0.0 3.7 0.0 0.8 0.0 0.0 2.2 0.0 0.0 0.0 0.2 0.0 7.6 0.0 0.5 7.9 0.0 148.5 0.0 0.0 0.4 1.4 0.2 58.2 53.8 52.1 0.2 4.9 0.7 0.2 0.1 0.1 0.1 22.7 0.2 5.0 13.3 73.6 0.3 0.4 0.0 1.5 0.0 0.0 0.0 0.8 0.0 2.4 0.0 5.0 4.9 0.0 0.0 2.0 6.4 0.0 0.0 0.0 0.0 1.8 0.7 177.1 135.6 21.6 212.8 105.6 642.6 290.3 257.1 193.0 95.5 264.9 51.8 0.8 0.0 0.0 29.0 12.5 15.8 1.3 4.3 0.6 139.6 11.4 14.9 1.4 2.8 4.3 389.9 52.1 1.0 1.0 18.2 277.8 8.6 12.8 44.3 8.7 3.6 3045.7 2.7 64.8 0.7 69.0 17.2 112.1 35.2 0.0 2.5 0.0 0.5 1.7 437.4 118.8 218.9 54.9 0.3 17.2 52.9 3.4 10.5 56.9 22.5 0.4 96.2 1.0 72.9 26.0 23.1 628.8 7.2 4.5 30.4 21.6 1601.1 24.8 148.2 0.0 0.3 12.6 32.5 82.2 0.2 11.5 1.9 20.1 0.2 15.6 3.7 PCSK2 "NEC2, PC2, SPC2" ENSG00000125851 "Proprotein convertase subtilisin/kexin type 2" P16519 20 17226107-17484578 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 28.5;brain: 30.2;retina: 35.8;thyroid gland: 56.9" "Cell type enhanced" "Detected in many" "Early spermatids: 87.3;Excitatory neurons: 322.8;Horizontal cells: 132.9;Inhibitory neurons: 148.8;Melanocytes: 209.9;Muller glia cells: 452.7" "Cancer enriched" "Detected in many" 4 "thyroid cancer: 65.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 60.0;SCLC-21H: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049627 Approved Approved Vesicles "Secreted in other tissues" NA NA 18000 "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA049627: AB_2680835" "unprognostic (2.03e-3)" "unprognostic (1.61e-1)" "unprognostic (3.13e-1)" "unprognostic (2.18e-1)" "unprognostic (2.13e-1)" "unprognostic (6.84e-2)" "unprognostic (3.07e-3)" "unprognostic (4.31e-1)" "unprognostic (5.88e-2)" "unprognostic (2.50e-3)" "unprognostic (2.14e-1)" "unprognostic (7.26e-5)" "unprognostic (2.29e-1)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-1)" 0.7 28.5 8.6 0.8 14.9 0.5 0.4 0.1 30.2 1.6 0.0 6.9 4.8 0.2 0.3 1.1 1.0 0.5 4.7 15.8 11.1 0.2 0.2 2.5 0.0 2.2 1.3 9.0 19.8 0.8 2.0 0.6 2.6 1.4 1.7 35.8 1.7 1.2 0.1 14.1 2.1 0.4 1.4 0.1 8.1 4.8 13.2 0.0 56.9 0.1 0.1 3.0 2.4 11.9 0.0 0.0 60.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 14.9 0.1 30.2 15.8 11.1 2.2 1.3 2.6 1.4 13.2 11.9 0.1 0.0 7.3 7.8 0.0 8.2 0.0 0.0 1.2 28.1 0.0 0.0 1.2 0.0 0.6 0.0 6.2 0.0 0.0 0.0 0.0 0.0 87.3 0.0 0.0 1.3 0.0 0.0 322.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 132.9 148.8 0.6 0.0 0.0 1.3 6.3 2.8 0.2 209.9 8.4 0.0 452.7 0.0 44.7 6.4 2.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.5 1.2 1.0 0.3 0.2 1.4 0.0 0.1 0.6 0.0 0.1 PDE6G "PDEG, RP57" ENSG00000185527 "Phosphodiesterase 6G" P18545 17 81650459-81663112 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 99 "retina: 2050.3" "Cell type enriched" "Detected in many" 6 "Rod photoreceptor cells: 4448.6" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "basophil: 127.0;NK-cell: 220.2" "Group enriched" "Detected in all" 6 "granulocytes: 127.0;NK-cells: 220.2" "Cell line enhanced" "Detected in some" "Hep G2: 5.2;NB-4: 5.8;NTERA-2: 8.9;REH: 11.9;SuSa: 6.2" "Region enhanced" "Detected in some" "hippocampal formation: 4.7" "Not detected" "Not detected" HPA045118 Supported Uncertain Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 5: NTERA-2 - Transcription" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles "HPA045118: AB_2732517" "unprognostic (6.16e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.51e-3)" "unprognostic (1.68e-1)" "unprognostic (1.46e-2)" "unprognostic (6.33e-2)" "unprognostic (3.80e-2)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (4.85e-2)" "unprognostic (5.01e-2)" "unprognostic (1.94e-2)" "unprognostic (5.71e-2)" "unprognostic (5.44e-2)" "unprognostic (2.73e-1)" "unprognostic (1.14e-1)" 1.5 0.3 0.0 4.7 0.1 7.8 0.9 0.2 0.5 1.0 0.2 1.6 0.6 0.2 0.1 0.8 0.7 2.5 0.4 0.1 0.7 2.1 4.2 3.0 20.6 0.1 0.2 0.0 0.0 0.1 0.1 12.0 0.2 0.2 1.0 2050.3 0.5 0.4 1.2 0.3 1.6 0.9 0.1 19.9 1.7 0.8 0.3 8.3 0.4 0.3 7.1 3.0 0.1 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.3 0.1 0.2 0.0 0.9 0.0 0.0 0.0 0.0 5.2 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.4 2.8 0.2 0.1 0.2 0.4 0.3 0.0 5.8 8.9 0.0 0.0 11.9 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.1 0.1 6.2 0.1 0.8 1.2 0.2 0.0 0.0 0.1 0.1 0.6 0.9 0.4 3.1 0.1 127.0 18.1 30.5 4.1 26.2 1.3 2.7 0.8 2.3 28.9 5.1 2.1 7.4 2.4 220.2 15.5 2.9 0.1 13.5 0.0 0.1 0.2 0.5 0.1 0.7 0.1 0.2 0.2 0.1 0.3 0.2 0.3 0.0 0.6 0.3 1.1 0.9 0.0 0.0 0.6 422.5 0.3 0.4 0.2 0.0 0.0 5.5 517.1 0.2 4.3 0.1 1.9 0.4 0.8 1.5 0.3 27.2 0.0 1.7 0.2 0.2 0.4 0.2 0.0 0.5 23.6 0.1 2.9 0.2 22.6 262.5 0.1 0.2 0.0 4.8 8.0 2.3 0.0 4.4 3.6 0.0 13.3 709.0 11.3 0.0 0.1 0.2 0.0 0.0 0.8 0.1 0.1 1.0 0.0 4448.6 0.0 0.1 0.1 1.1 0.2 0.3 1.4 0.3 1.7 2.1 0.0 0.1 PDE6H ENSG00000139053 "Phosphodiesterase 6H" Q13956 12 14973042-14981865 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 226 "retina: 911.3" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 831.9;Rod photoreceptor cells: 218.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "AN3-CA: 1.0" "Low region specificity" "Detected in single" HPA045118 Supported Uncertain Vesicles NA NA "Cluster 79: Retina - Phototransduction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "HPA045118: AB_2732517" "unprognostic (1.47e-3)" "unprognostic (1.07e-2)" 0.0 0.4 0.3 0.0 0.4 4.0 0.0 0.1 1.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 911.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.1 1.0 0.3 2.3 0.3 0.4 0.5 0.2 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.9 0.0 0.0 0.1 0.0 0.0 0.0 831.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.5 0.0 21.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 23.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.6 81.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 218.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.0;Endothelial cells: 60.6;Langerhans cells: 44.3;Macrophages: 25.5;Pancreatic endocrine cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Cell line enhanced" "Detected in many" "A-431: 33.8;EFO-21: 69.2;HUVEC TERT2: 52.6;SK-BR-3: 53.5;TIME: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" NA NA 4390000 950000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" 32.6 6.4 14.7 7.1 10.7 0.4 24.0 10.3 22.2 7.5 4.8 20.6 4.9 8.9 5.2 6.2 7.2 11.7 31.2 12.0 9.8 17.0 3.7 28.1 7.4 13.6 12.4 3.8 8.8 8.9 4.0 40.2 12.0 7.6 3.5 0.8 10.6 5.2 18.7 10.3 9.1 9.2 10.6 6.6 7.9 3.4 16.0 2.1 16.1 11.0 1.6 8.5 6.6 9.4 33.8 2.6 8.4 0.0 0.0 0.0 9.9 0.1 0.4 0.2 0.0 13.0 10.3 0.0 69.2 0.0 3.1 12.4 0.5 2.8 0.0 0.1 0.2 0.7 1.1 4.8 4.3 0.0 18.1 0.0 0.3 0.0 0.4 0.9 52.6 0.0 1.3 6.1 1.9 13.7 0.1 0.1 3.2 8.1 3.4 0.0 0.3 22.8 27.7 0.1 0.2 0.0 0.6 53.5 0.2 6.0 24.3 0.1 68.1 0.1 6.4 0.1 7.5 0.1 0.4 0.3 0.1 1.5 31.3 0.0 0.0 0.0 7.3 0.1 10.0 0.0 4.3 5.6 0.0 0.0 3.6 1.9 0.1 0.0 0.4 1.3 2.3 2.1 14.7 10.7 10.3 22.2 12.0 9.8 13.6 12.4 12.0 10.6 16.0 9.4 75.0 0.0 1.1 0.0 0.6 2.8 1.2 3.8 1.2 0.7 5.1 7.1 3.1 0.0 1.3 7.3 0.0 7.3 4.0 0.1 0.0 20.0 1.3 4.0 0.7 60.6 1.8 0.0 2.8 3.6 6.5 1.6 0.0 5.6 0.0 13.1 16.8 1.4 7.7 0.0 0.9 0.7 4.1 2.6 44.3 0.1 0.6 25.5 1.8 14.0 1.1 0.3 0.0 0.0 0.2 54.7 0.0 0.0 0.0 2.7 0.1 1.9 0.9 0.1 6.6 4.7 9.6 0.3 1.6 1.1 1.4 4.5 2.0 1.2 0.1 0.6 PEX2 "PAF-1, PMP35, PXMP3, RNF72, ZWS3" ENSG00000164751 "Peroxisomal biogenesis factor 2" P28328 8 76980258-77001044 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010983, HPA011410, HPA027729" Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA010983: , HPA011410: AB_1854922, HPA027729: AB_10610416" "unprognostic (6.42e-2)" "unprognostic (2.90e-2)" "unprognostic (4.64e-2)" "unprognostic (2.35e-1)" "unprognostic (9.91e-2)" "unprognostic (2.33e-1)" "unprognostic (6.19e-2)" "unprognostic (2.22e-1)" "unprognostic (3.16e-2)" "unprognostic (1.37e-1)" "unprognostic (2.85e-2)" "unprognostic (2.07e-2)" "unprognostic (9.57e-3)" "unprognostic (2.48e-1)" "unprognostic (9.49e-2)" "unprognostic (3.06e-2)" "unprognostic (1.09e-3)" 39.8 45.9 33.1 33.5 36.6 35.8 53.9 34.2 45.6 40.7 38.6 43.1 39.8 33.3 42.4 32.9 41.8 31.9 39.7 32.1 35.1 53.6 43.7 36.5 39.4 37.3 34.5 33.3 39.0 57.7 27.2 24.7 37.6 44.2 39.6 66.5 50.9 83.4 61.8 24.5 41.0 35.3 37.3 36.5 48.3 22.1 34.5 48.8 53.2 44.6 35.7 35.7 31.3 43.3 88.2 29.3 46.9 47.9 50.7 63.2 24.5 64.4 75.3 49.9 55.2 18.4 76.9 50.2 93.6 59.9 39.7 33.3 33.1 50.1 61.2 93.3 28.5 61.1 26.0 28.3 33.9 51.5 46.5 70.9 43.5 37.8 45.6 77.0 55.3 79.3 34.4 46.7 53.9 26.4 90.4 30.1 27.2 126.4 26.3 16.5 37.4 42.1 59.9 61.6 16.7 43.0 41.9 192.0 36.9 39.8 58.7 36.1 54.7 44.4 58.1 57.7 32.4 86.0 53.8 87.9 56.5 26.7 50.2 179.9 55.6 102.6 57.2 58.0 51.2 46.1 39.6 46.5 46.3 50.5 51.6 49.3 38.6 83.1 67.8 46.8 48.6 71.7 33.1 36.6 34.2 45.6 32.1 35.1 37.3 34.5 37.6 37.3 34.5 43.3 28.0 48.1 25.2 32.3 29.7 18.1 31.0 57.8 28.5 28.9 38.9 33.1 27.2 28.6 38.4 27.6 12.5 42.8 38.3 30.2 133.1 52.3 5.6 36.5 19.9 20.7 28.9 25.6 11.9 49.1 24.8 29.8 20.4 22.2 18.3 20.2 25.7 36.7 26.6 13.5 15.2 37.5 48.8 39.1 22.4 7.3 29.5 26.8 28.4 16.9 36.3 68.4 53.5 31.7 45.9 42.0 28.2 35.7 41.7 36.3 43.3 61.4 36.6 34.4 6.6 34.9 24.6 13.7 20.8 28.6 21.0 34.8 37.6 27.7 30.0 43.0 PFAS "FGARAT, GATD8, KIAA0361, PURL" ENSG00000178921 "Phosphoribosylformylglycinamidine synthase" O15067 17 8247618-8270491 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 49.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022140, HPA022886" Enhanced Approved Vesicles NA NA 670000 "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA022140: AB_1855232, HPA022886: AB_1855233" "unprognostic (1.90e-1)" "unprognostic (9.21e-2)" "unprognostic (2.12e-1)" "unprognostic (5.19e-3)" "unprognostic (2.59e-1)" "unprognostic (6.40e-2)" "prognostic unfavorable (9.19e-4)" "unprognostic (3.19e-1)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "unprognostic (5.47e-3)" "unprognostic (1.08e-3)" "unprognostic (9.51e-3)" "unprognostic (3.63e-2)" "unprognostic (6.57e-2)" "unprognostic (2.88e-3)" "unprognostic (3.85e-1)" 8.4 9.9 4.7 7.8 5.1 9.8 8.2 6.2 5.8 7.8 2.8 6.7 4.8 9.0 2.6 8.4 8.0 2.8 6.3 5.1 3.3 11.0 10.1 5.8 9.8 3.9 3.9 9.7 10.3 5.6 5.5 5.2 4.6 6.9 5.6 5.8 6.4 4.7 6.4 6.8 7.7 6.8 3.3 11.0 7.8 7.8 3.9 7.5 7.8 3.2 8.2 7.6 6.2 6.0 15.6 67.0 33.8 50.2 12.1 10.0 38.7 19.4 7.4 35.1 26.4 32.9 13.7 69.8 30.8 11.4 12.4 35.1 78.5 25.6 25.8 30.6 64.0 40.0 63.2 41.9 10.4 32.9 28.3 9.5 6.2 40.5 25.5 9.9 29.5 36.6 54.8 10.1 13.7 23.0 58.1 28.4 55.7 8.5 29.9 86.0 35.2 32.6 16.1 25.5 20.4 31.7 24.1 15.3 22.2 17.9 15.3 14.9 20.9 19.2 25.0 35.7 49.0 11.8 23.5 33.7 21.0 45.4 32.9 20.2 5.1 12.7 6.8 4.5 8.7 14.8 8.8 7.9 4.4 16.7 10.9 8.6 49.1 5.2 3.7 12.9 5.0 2.3 4.7 5.1 6.2 5.8 5.1 3.3 3.9 3.9 4.6 3.3 3.9 6.0 2.9 0.0 7.9 3.9 6.0 2.4 1.7 1.9 1.8 8.1 4.5 3.7 4.3 1.5 4.1 3.7 6.2 5.2 3.2 2.1 0.0 3.7 2.1 2.4 5.9 3.6 0.0 9.2 5.8 3.0 4.3 4.0 5.6 3.7 1.3 9.7 2.5 4.2 4.6 1.7 5.4 3.5 2.0 2.5 1.4 1.1 5.3 3.4 3.6 4.7 4.5 1.6 4.1 6.6 3.9 1.9 4.9 1.5 5.3 2.9 0.8 2.7 5.1 7.3 0.0 5.1 3.2 5.6 8.8 3.9 2.0 3.1 3.3 7.7 6.2 1.4 PGBD2 ENSG00000185220 "PiggyBac transposable element derived 2" Q6P3X8 1 248906196-248919946 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "HPA029888, HPA029889, HPA029890" Uncertain Approved Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA029888: AB_10600088, HPA029889: AB_10611386, HPA029890: AB_10602002" "unprognostic (1.06e-2)" "unprognostic (8.05e-2)" "unprognostic (2.56e-2)" "unprognostic (3.03e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.08e-4)" "unprognostic (1.94e-2)" "unprognostic (2.11e-2)" "unprognostic (2.71e-3)" "unprognostic (1.84e-1)" "unprognostic (2.59e-1)" "unprognostic (1.18e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (2.41e-1)" "unprognostic (7.91e-2)" "unprognostic (1.25e-1)" "prognostic favorable (2.05e-4)" 3.2 3.6 3.5 5.4 3.7 4.3 5.8 5.4 3.9 4.9 2.8 4.6 5.9 4.8 5.1 6.0 3.8 4.7 2.8 2.9 4.3 3.7 7.2 3.6 7.5 3.5 3.0 5.6 6.7 3.3 2.7 5.8 3.6 5.1 6.1 4.4 5.4 3.3 1.4 8.1 7.1 3.6 2.1 9.4 5.2 6.0 4.1 5.6 6.5 2.4 7.1 4.4 4.7 6.3 4.4 5.7 8.5 5.2 7.7 5.0 10.7 4.1 3.4 6.9 6.3 4.2 5.6 11.2 5.0 3.9 3.8 6.9 4.7 5.2 7.6 6.7 2.1 10.7 10.0 6.4 4.4 5.9 10.3 4.5 5.5 8.2 4.5 5.5 3.9 3.8 17.5 9.5 5.0 7.3 2.0 6.5 8.4 14.6 6.6 13.1 2.8 3.5 4.0 5.5 3.0 5.6 6.0 8.5 7.0 5.9 3.6 11.2 5.0 4.7 4.5 4.3 4.6 8.8 9.2 4.1 5.0 12.7 4.4 11.0 6.0 9.4 6.1 4.4 6.1 8.3 5.5 5.9 5.5 8.4 5.5 6.8 4.6 5.9 6.8 2.7 4.1 4.1 3.5 3.7 5.4 3.9 2.9 4.3 3.5 3.0 3.6 2.1 4.1 6.3 5.3 0.0 8.9 2.6 11.2 5.2 2.9 7.6 14.8 3.6 7.3 5.6 2.2 2.8 9.1 5.5 2.1 11.5 7.9 6.9 1.9 5.1 3.5 6.0 4.9 5.9 1.2 17.9 2.3 3.0 4.4 3.5 6.1 6.9 2.5 7.8 3.3 3.4 2.9 1.7 2.7 4.3 6.1 3.3 4.4 2.7 3.1 3.7 7.2 2.8 4.6 3.2 6.2 6.0 4.3 2.2 6.0 1.9 5.7 2.8 9.0 3.0 4.6 2.7 0.0 4.0 5.6 14.5 10.2 7.9 6.5 27.8 7.8 4.8 5.1 2.1 PHGR1 ENSG00000233041 "Proline, histidine and glycine rich 1" C9JFL3 15 40351033-40356434 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 2541.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 19911.4;Intestinal goblet cells: 8220.0;Paneth cells: 9497.7;Proximal enterocytes: 51149.4" "Group enriched" "Detected in many" 16 "colorectal cancer: 248.3;stomach cancer: 94.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "OE19: 833.5" HPA068787 Enhanced Approved Vesicles NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA068787: AB_2686035" "prognostic favorable (2.05e-4)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (1.18e-1)" "unprognostic (2.80e-1)" "unprognostic (1.20e-1)" "unprognostic (1.27e-2)" 3.7 0.4 0.1 88.8 0.2 0.2 11.1 0.3 0.1 0.8 0.0 2541.0 881.0 1.2 0.0 2.0 3.5 0.3 0.3 0.1 0.1 1.9 1.0 0.2 1.2 0.1 0.1 0.5 1.9 0.0 0.5 0.0 0.1 2.5 370.7 0.0 0.3 3.0 0.4 3.7 2320.2 17.3 0.1 0.4 177.1 0.3 0.1 0.0 0.4 0.0 0.0 5.6 1.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.0 0.1 833.5 0.3 0.1 0.0 10.8 0.0 1.5 61.5 7.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 46.0 0.0 0.2 0.3 0.0 0.0 40.2 38.0 0.0 117.2 0.0 0.0 0.0 0.0 0.1 19911.4 0.0 2.5 0.1 0.0 0.0 0.2 1938.2 0.0 0.0 0.2 0.0 0.5 884.8 0.1 213.9 0.0 0.0 0.6 0.0 0.0 0.0 8220.0 20.3 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 9497.7 0.0 2.1 1.1 51149.4 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 32.6 0.0 4881.6 1.0 PICALM "CALM, CLTH" ENSG00000073921 "Phosphatidylinositol binding clathrin assembly protein" Q13492 11 85957175-86069882 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Endocytosis "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 500.3;Oligodendrocytes: 709.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 40.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019053, HPA019061" Enhanced Enhanced Vesicles NA NA 40000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA019053: AB_1855361, HPA019061: AB_1855362" "unprognostic (9.27e-3)" "unprognostic (7.29e-2)" "unprognostic (3.51e-1)" "unprognostic (6.83e-2)" "unprognostic (5.13e-2)" "unprognostic (1.93e-1)" "unprognostic (5.36e-3)" "unprognostic (9.02e-3)" "unprognostic (9.80e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (6.61e-4)" "unprognostic (4.31e-1)" "prognostic favorable (2.02e-6)" "unprognostic (1.26e-2)" "unprognostic (5.21e-3)" "unprognostic (2.52e-1)" "unprognostic (1.02e-1)" 183.5 62.5 97.1 120.4 162.1 111.4 111.5 119.3 118.7 86.4 43.8 86.3 106.3 79.3 52.4 109.1 66.1 127.0 87.9 91.7 110.8 168.5 147.0 99.4 82.7 125.2 130.7 94.4 80.6 120.6 36.5 157.2 131.6 73.1 83.1 71.5 62.3 93.6 75.8 74.2 115.5 135.3 106.0 126.5 73.0 64.9 120.7 93.1 75.7 101.9 96.7 139.5 73.5 194.7 167.0 78.4 121.1 85.9 185.5 188.8 228.5 211.7 274.7 164.4 143.0 310.7 222.4 126.0 210.8 342.6 171.1 134.6 129.4 154.2 232.8 38.6 45.0 364.9 101.5 98.9 185.6 87.2 158.3 166.6 161.7 308.7 253.3 275.1 178.7 85.9 239.1 103.0 305.2 98.2 103.9 76.8 66.9 269.0 42.7 69.8 182.2 91.1 312.5 139.2 72.9 58.7 258.4 85.4 68.7 156.5 115.6 67.0 196.9 298.6 104.1 355.0 170.2 36.7 107.1 118.4 70.8 64.6 206.6 6.4 13.5 7.5 5.7 11.7 4.9 3.1 4.2 8.0 11.4 2.1 4.2 4.0 40.6 7.1 12.5 3.9 6.4 5.3 97.1 162.1 119.3 118.7 91.7 110.8 125.2 130.7 131.6 106.0 120.7 194.7 147.1 35.3 58.9 134.5 33.3 116.0 44.4 33.0 30.1 20.8 34.8 28.6 46.4 42.9 34.3 71.7 12.5 42.9 43.9 64.2 31.3 57.7 59.3 32.3 32.8 98.7 25.1 88.8 144.7 37.6 127.1 44.6 34.1 50.9 48.2 23.2 71.4 52.3 85.0 40.4 140.7 30.1 30.5 142.8 229.2 95.4 35.8 127.4 60.5 500.3 92.1 22.6 32.0 188.0 709.3 90.2 55.3 43.6 39.1 49.5 71.4 84.0 41.0 16.3 78.9 36.4 92.7 17.3 14.1 34.4 96.5 41.3 38.9 23.6 30.6 77.7 PIGP "DCRC, DSCR5, DSRC" ENSG00000185808 "Phosphatidylinositol glycan anchor biosynthesis class P" P57054 21 37062846-37073170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 350.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026921 Uncertain Approved Vesicles Yes No "Cluster 30: Non-specific - Translation" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA026921: AB_1847874" "unprognostic (4.47e-3)" "unprognostic (9.45e-2)" "unprognostic (3.03e-1)" "unprognostic (2.40e-1)" "unprognostic (2.85e-2)" "unprognostic (1.92e-2)" "unprognostic (1.92e-2)" "unprognostic (5.54e-2)" "unprognostic (1.55e-1)" "unprognostic (1.22e-2)" "unprognostic (4.21e-3)" "unprognostic (1.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.93e-1)" "unprognostic (5.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.55e-2)" 33.9 41.3 18.7 12.5 20.2 9.1 35.4 22.4 24.7 22.9 24.8 24.2 19.0 18.3 107.2 16.8 25.7 22.5 40.1 18.1 22.8 35.9 54.7 21.6 16.6 22.8 21.6 27.9 41.4 51.9 38.0 20.9 22.6 33.7 27.4 28.6 32.2 26.7 44.0 12.4 15.5 17.1 22.1 14.9 22.8 36.5 20.0 22.0 36.3 42.8 19.7 26.2 13.2 25.4 25.9 11.5 23.7 14.8 41.5 28.6 16.9 21.9 38.7 18.6 21.1 15.4 53.7 37.1 45.7 32.0 81.4 19.4 22.7 25.5 18.5 37.4 36.1 86.2 13.8 21.3 26.3 26.9 16.6 26.5 47.2 33.4 43.0 42.2 35.1 80.5 50.7 61.8 38.5 16.5 32.9 25.5 19.6 76.8 27.9 31.0 12.1 37.0 48.2 13.3 49.2 29.8 61.4 43.0 81.8 33.6 35.2 53.2 18.3 12.9 6.6 14.8 19.3 81.1 96.5 42.0 38.1 30.5 43.4 0.4 13.5 3.7 19.6 20.3 24.8 34.2 25.1 21.6 20.9 28.1 33.3 29.0 1.9 16.8 22.6 30.9 20.6 15.6 18.7 20.2 22.4 24.7 18.1 22.8 22.8 21.6 22.6 22.1 20.0 25.4 37.4 28.9 41.8 9.8 37.0 33.0 58.9 88.9 35.3 21.2 74.1 86.4 82.4 42.9 65.1 44.1 10.4 60.7 29.4 21.6 90.1 61.8 79.3 67.0 35.9 31.3 44.9 25.7 6.9 71.3 52.4 48.9 30.1 49.3 15.9 32.2 35.3 79.8 66.7 16.8 8.7 63.9 65.1 57.6 39.9 75.6 69.0 44.1 37.4 2.8 50.2 37.0 23.7 7.5 18.2 57.7 50.3 35.0 54.3 45.6 52.3 97.1 86.9 33.6 65.7 32.7 44.6 350.8 177.5 44.2 26.3 52.3 31.7 62.6 53.1 63.7 PINLYP ENSG00000234465 "Phospholipase A2 inhibitor and LY6/PLAUR domain containing" A6NC86 19 43575801-43583964 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 23.5;Proximal tubular cells: 19.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 21.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 73.1;HMC-1: 46.6;JURKAT: 37.1;REH: 29.8;THP-1: 36.6" "Not detected" "Not detected" HPA061218 Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA061218: AB_2684453" "unprognostic (6.72e-2)" "unprognostic (6.21e-2)" "unprognostic (4.72e-1)" "unprognostic (3.13e-2)" "unprognostic (2.46e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.22e-2)" "unprognostic (5.07e-2)" "unprognostic (2.00e-1)" "unprognostic (2.85e-2)" "unprognostic (1.14e-1)" "unprognostic (4.36e-3)" "unprognostic (1.95e-2)" "unprognostic (1.68e-1)" "unprognostic (1.08e-1)" "unprognostic (3.60e-2)" 9.9 3.5 16.3 3.3 16.7 2.7 8.5 18.1 22.1 17.3 16.1 13.3 1.4 14.7 9.4 10.5 17.1 9.3 9.8 16.1 16.8 22.9 2.1 7.7 5.0 17.2 17.0 19.6 2.4 0.7 14.9 2.8 16.0 13.5 3.0 2.6 5.8 10.4 1.7 7.6 6.4 11.1 16.4 8.4 7.3 5.4 17.4 10.6 11.8 3.3 5.2 10.3 13.0 15.7 0.7 0.3 1.9 0.3 3.4 4.5 0.4 0.8 1.2 1.6 4.3 0.0 0.1 0.0 0.2 19.0 1.8 4.0 0.0 0.2 1.5 0.1 0.2 73.1 0.8 0.1 10.3 0.0 46.6 10.2 0.4 10.3 0.2 4.3 2.7 37.1 0.9 1.0 0.7 0.4 8.9 1.1 1.8 0.1 0.7 29.8 0.2 0.0 0.8 0.4 0.3 0.0 0.0 0.4 0.1 0.3 0.1 36.6 1.2 4.7 0.9 0.1 3.1 0.0 0.0 4.4 16.0 0.0 0.4 10.4 1.5 0.7 3.0 1.2 3.6 1.7 0.9 2.5 2.3 4.7 0.3 3.6 0.5 1.4 0.2 21.0 2.0 1.7 16.3 16.7 18.1 22.1 16.1 16.8 17.2 17.0 16.0 16.4 17.4 15.7 1.8 12.8 3.2 2.3 1.1 3.6 10.0 5.6 8.6 6.1 2.4 5.6 2.8 8.6 5.7 9.2 6.2 0.4 1.8 0.1 23.5 1.3 6.4 2.1 9.9 4.3 0.0 4.4 0.5 0.4 0.4 9.1 2.0 2.0 0.0 7.6 5.7 0.0 5.1 6.7 1.1 0.8 2.0 1.0 3.9 7.3 11.5 2.7 5.4 1.9 3.3 5.6 0.0 5.0 0.5 0.4 0.1 9.8 1.7 5.2 0.7 19.0 15.0 3.3 0.0 2.1 5.9 2.3 1.2 6.7 3.1 0.1 1.2 13.6 1.7 6.6 PITPNM2 "NIR3, RDGB2, RDGBA2" ENSG00000090975 "Phosphatidylinositol transfer protein membrane associated 2" Q9BZ72 12 122983480-123150015 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "lymphoid tissue: 87.3" "Cell type enhanced" "Detected in many" "Astrocytes: 33.6;Cone photoreceptor cells: 54.2;Excitatory neurons: 51.3;Horizontal cells: 40.4;Inhibitory neurons: 41.3;Late spermatids: 87.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 29.5;JURKAT: 35.6;MOLT-4: 55.0;WM-115: 25.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003414, HPA003978" Approved Supported Vesicles NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA003414: AB_1855410, HPA003978: AB_1855411" "unprognostic (2.43e-1)" "unprognostic (9.29e-2)" "unprognostic (2.00e-1)" "unprognostic (5.39e-2)" "unprognostic (2.14e-1)" "unprognostic (6.76e-2)" "unprognostic (2.26e-2)" "unprognostic (1.08e-1)" "unprognostic (2.55e-1)" "unprognostic (6.44e-2)" "unprognostic (1.03e-1)" "unprognostic (9.28e-2)" "unprognostic (1.50e-3)" "unprognostic (7.66e-2)" "unprognostic (1.16e-1)" "unprognostic (1.19e-2)" "unprognostic (9.99e-2)" 4.6 9.0 11.4 4.6 12.3 5.2 3.7 6.7 15.6 6.1 18.7 5.7 4.7 4.6 3.7 4.7 3.7 2.6 4.9 13.1 1.8 8.7 11.0 6.8 3.2 4.9 3.6 15.3 3.5 6.6 8.4 3.6 1.6 3.5 2.5 15.2 2.4 3.8 5.0 4.1 4.9 5.7 0.4 4.4 4.6 7.3 4.9 87.3 3.7 3.3 1.9 7.0 4.9 3.8 4.6 8.7 2.8 4.1 1.9 3.7 16.8 0.7 1.1 2.3 1.2 3.8 3.7 0.0 3.7 1.5 4.8 12.8 2.3 2.2 0.8 0.3 2.8 29.5 5.7 10.5 1.3 1.1 6.0 1.8 3.8 3.0 2.3 10.8 4.5 35.6 6.8 0.3 2.9 2.9 55.0 6.1 3.2 1.4 3.9 15.7 0.2 11.4 4.1 4.7 2.5 0.9 6.3 5.2 4.1 1.6 1.1 3.1 13.3 3.3 3.7 5.4 5.1 0.8 1.0 20.4 8.2 2.2 25.4 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.2 0.6 0.0 0.2 0.5 0.4 0.0 1.9 0.0 0.0 0.3 0.7 11.4 12.3 6.7 15.6 13.1 1.8 4.9 3.6 1.6 0.4 4.9 3.8 16.2 0.0 5.0 33.6 2.8 3.6 0.7 0.7 2.2 19.6 1.5 1.5 7.3 2.8 1.6 9.2 54.2 1.3 6.3 6.3 1.9 3.3 33.0 3.7 3.6 9.3 0.0 1.7 51.3 4.5 6.5 3.8 2.0 5.2 1.3 0.8 6.4 16.3 0.5 40.4 41.3 3.7 0.0 0.6 1.1 87.7 1.8 3.6 1.8 10.3 1.3 3.7 10.3 22.1 1.8 3.9 0.3 4.9 2.2 1.1 6.1 2.6 0.1 15.8 0.0 2.1 2.5 8.2 4.7 3.6 1.6 3.7 4.8 0.4 2.6 0.6 PKN3 "PKNbeta, UTDP4-1" ENSG00000160447 "Protein kinase N3" Q6P5Z2 9 128702503-128720916 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 27.1;Breast glandular cells: 15.3;Endothelial cells: 17.9;Microglial cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 78.0;REH: 42.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA045390, HPA058305" Uncertain Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "HPA045390: AB_2679308, HPA058305: AB_2683674" "unprognostic (4.36e-2)" "unprognostic (5.70e-2)" "unprognostic (2.68e-2)" "unprognostic (7.62e-2)" "unprognostic (2.23e-1)" "unprognostic (2.65e-2)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.78e-1)" "unprognostic (3.68e-1)" "unprognostic (1.48e-1)" "unprognostic (7.91e-2)" "unprognostic (8.73e-3)" "unprognostic (6.18e-3)" "unprognostic (9.99e-2)" "unprognostic (7.23e-2)" "unprognostic (2.36e-1)" 12.6 2.7 6.1 2.6 5.8 2.6 13.2 7.3 6.8 6.3 4.7 5.1 4.7 7.6 0.6 5.2 7.0 2.3 15.9 5.0 5.2 9.0 4.1 11.1 2.1 6.1 5.9 2.8 5.3 2.2 1.8 3.3 6.0 5.4 0.9 0.1 11.5 2.0 3.6 5.4 6.2 2.8 5.4 9.5 7.0 2.6 7.2 2.8 6.9 3.4 1.1 6.9 6.3 5.3 2.9 14.1 11.3 17.2 0.1 0.3 27.7 8.7 2.7 12.6 13.0 0.1 10.1 0.1 8.4 4.7 2.6 19.0 13.8 2.1 2.9 9.0 26.0 17.1 78.0 20.5 2.1 2.1 3.0 0.6 0.7 6.8 1.9 2.7 25.1 5.0 39.6 1.9 2.3 26.9 2.6 9.2 10.5 13.1 4.1 42.4 21.3 3.8 5.3 1.7 1.9 8.5 6.6 3.5 6.5 6.1 12.3 13.6 21.9 0.1 10.3 20.0 6.7 6.2 2.9 5.7 1.6 2.2 8.0 0.0 0.0 0.3 0.1 0.1 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 6.1 5.8 7.3 6.8 5.0 5.2 6.1 5.9 6.0 5.4 7.2 5.3 27.1 0.0 2.0 0.3 1.2 1.0 1.7 1.7 3.4 0.2 15.3 3.6 1.8 4.3 2.1 0.0 0.0 2.2 2.0 1.5 0.0 1.9 0.2 2.2 1.1 17.9 0.0 5.0 0.3 2.6 6.1 1.8 5.1 4.9 0.0 5.0 9.3 0.4 1.9 0.0 0.2 1.7 0.0 0.8 2.3 0.9 1.5 0.8 0.0 13.1 1.2 0.3 4.1 0.0 0.1 3.3 1.5 0.7 1.6 1.1 2.6 0.6 0.5 0.2 0.0 0.7 1.3 2.8 6.6 2.8 1.0 1.4 1.9 1.4 2.5 1.7 PLCH1 "DKFZp434C1372, KIAA1069, MGC117152, PLCeta1, PLCL3" ENSG00000114805 "Phospholipase C eta 1" Q4KWH8 3 155375580-155745071 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.6;retina: 12.4" "Group enriched" "Detected in many" 4 "Astrocytes: 93.7;Early spermatids: 206.2;Excitatory neurons: 126.0;Inhibitory neurons: 131.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 12.3;AF22: 39.0;HEL: 10.1;NTERA-2: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036176, HPA057978" Uncertain Enhanced Vesicles NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA036176: AB_10671837, HPA057978: AB_2683569" "unprognostic (1.08e-2)" "unprognostic (3.68e-1)" "unprognostic (2.17e-2)" "unprognostic (1.55e-2)" "unprognostic (3.50e-4)" "unprognostic (6.41e-2)" "unprognostic (2.94e-5)" "unprognostic (5.04e-2)" "unprognostic (2.41e-1)" "unprognostic (2.24e-3)" "unprognostic (4.84e-2)" "unprognostic (1.76e-2)" "prognostic favorable (3.03e-5)" "unprognostic (3.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-2)" 0.0 0.0 5.5 0.3 4.8 0.2 2.6 4.5 6.0 1.2 9.3 2.5 2.5 0.7 8.2 0.1 8.1 1.5 1.8 3.8 1.4 1.2 0.1 4.0 0.0 1.3 4.6 0.1 1.4 0.4 1.5 0.4 1.5 0.3 2.4 12.4 1.3 1.9 0.2 0.1 2.5 0.1 1.6 0.0 3.8 11.3 1.3 16.6 5.7 0.0 0.0 0.4 0.1 2.0 0.0 12.3 39.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.2 2.4 9.8 0.0 0.8 0.0 0.1 0.0 7.0 0.0 0.0 0.0 3.6 10.1 0.0 1.4 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.3 0.0 0.0 4.4 2.4 9.4 20.8 1.3 1.6 0.9 0.0 0.0 2.4 0.2 3.6 0.9 0.0 9.4 0.0 5.7 4.2 0.0 0.0 0.0 0.2 0.0 1.7 0.4 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 4.8 4.5 6.0 3.8 1.4 1.3 4.6 1.5 1.6 1.3 2.0 0.0 3.2 13.6 93.7 0.3 0.0 0.4 0.5 0.6 10.5 4.0 5.0 0.8 4.3 2.3 1.8 4.2 0.0 0.1 2.7 0.0 2.2 206.2 34.6 1.3 0.6 3.0 0.0 126.0 2.3 0.3 0.3 15.3 13.6 0.0 0.1 0.0 0.0 0.2 25.2 131.5 4.0 0.0 0.3 0.4 21.4 1.2 0.4 0.0 12.2 0.1 16.1 0.0 5.5 5.7 1.5 4.6 0.4 0.0 0.4 2.8 2.1 23.4 3.0 0.0 0.0 0.2 2.4 1.2 0.7 0.1 0.0 0.3 0.1 4.4 0.4 PLPP5 "DPPL1, HTPAP, PPAPDC1B" ENSG00000147535 "Phospholipid phosphatase 5" Q8NEB5 8 38263130-38269243 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 264.5;Prostatic glandular cells: 146.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 80.2;memory B-cell: 211.8;naive B-cell: 305.9" "Group enriched" "Detected in all" 7 "B-cells: 305.9;granulocytes: 80.2" "Cell line enhanced" "Detected in all" "RPMI-8226: 140.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055777 Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA055777: AB_2682915" "unprognostic (4.54e-2)" "unprognostic (2.51e-3)" "unprognostic (3.66e-2)" "prognostic favorable (1.48e-5)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (5.58e-2)" "prognostic favorable (8.72e-5)" "unprognostic (9.79e-2)" "prognostic favorable (2.42e-5)" "unprognostic (1.50e-1)" "unprognostic (5.08e-2)" "prognostic unfavorable (8.33e-10)" "unprognostic (3.82e-2)" "unprognostic (1.58e-1)" "unprognostic (1.59e-3)" "unprognostic (1.57e-2)" 12.6 18.6 12.5 21.5 13.0 16.6 24.4 15.8 16.1 29.4 36.5 30.2 41.6 16.1 81.7 13.9 28.3 27.9 8.6 12.6 14.4 27.6 33.0 16.0 28.1 12.7 13.5 18.6 114.5 13.7 52.4 14.0 12.4 74.5 35.5 8.5 85.7 30.5 4.8 10.7 40.3 11.4 11.5 28.0 46.1 7.8 13.5 10.2 29.2 3.0 32.3 21.2 14.1 13.0 15.1 29.7 17.4 35.7 33.2 32.1 23.9 42.1 52.7 21.0 27.3 13.8 22.7 1.0 35.1 43.8 30.5 16.5 14.5 30.9 18.2 9.6 9.3 26.6 13.1 40.5 56.3 7.8 30.8 25.3 31.5 29.4 38.3 37.2 34.7 34.9 1.3 67.2 25.9 31.2 17.7 13.0 26.5 61.2 10.0 19.1 12.8 140.0 53.3 19.4 13.6 20.8 17.3 26.5 25.4 15.4 56.9 15.0 21.2 14.8 13.1 25.2 11.3 41.5 29.4 4.5 41.0 20.5 26.1 80.2 12.9 23.4 13.4 13.7 23.0 211.8 17.8 17.7 12.2 305.9 8.8 8.5 8.0 22.4 19.7 26.0 18.0 17.0 12.5 13.0 15.8 16.1 12.6 14.4 12.7 13.5 12.4 11.5 13.5 13.0 22.2 9.6 46.2 0.0 110.8 0.0 81.8 0.0 25.6 5.9 49.4 42.3 0.0 32.9 21.7 75.4 16.7 45.1 14.8 12.4 43.0 68.0 30.6 70.3 27.3 27.9 44.9 9.9 0.0 89.9 43.5 41.5 50.4 54.8 31.5 38.1 17.5 23.4 36.5 62.2 0.0 62.6 0.0 10.1 0.0 8.9 17.7 23.0 0.0 0.0 12.0 37.4 18.6 0.0 0.0 57.2 31.1 9.4 264.5 146.3 74.3 24.9 55.4 3.6 13.1 22.8 18.9 31.4 12.3 20.8 0.0 88.1 25.2 18.5 44.1 59.1 PMAIP1 "APR, NOXA" ENSG00000141682 "Phorbol-12-myristate-13-acetate-induced protein 1" Q13794 18 59899996-59904305 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 803.1;Endometrial ciliated cells: 463.6;Glandular and luminal cells: 529.8;Squamous epithelial cells: 474.5;Suprabasal keratinocytes: 691.2;Urothelial cells: 569.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 169.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 169.8" "Cell line enhanced" "Detected in many" "GAMG: 207.5;U-138 MG: 202.1" HPA051063 Uncertain Uncertain Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "HPA051063: AB_2681330" "unprognostic (1.35e-3)" "unprognostic (5.02e-2)" "unprognostic (5.57e-2)" "unprognostic (4.88e-2)" "unprognostic (6.65e-3)" "unprognostic (3.76e-2)" "unprognostic (2.00e-3)" "unprognostic (1.26e-2)" "unprognostic (4.41e-2)" "unprognostic (6.12e-2)" "unprognostic (8.47e-3)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.15e-6)" "unprognostic (2.53e-1)" "unprognostic (7.68e-2)" "unprognostic (8.74e-2)" "unprognostic (1.09e-1)" 2.0 0.7 2.8 8.0 2.7 88.1 3.9 2.6 5.1 6.5 3.0 2.5 3.7 5.4 0.2 13.7 2.9 8.0 0.9 2.6 2.8 2.3 2.1 3.8 14.7 2.8 2.7 0.7 1.2 14.8 16.7 13.4 3.0 3.6 3.4 2.0 3.6 1.3 1.5 24.1 3.9 1.9 2.7 4.6 2.5 3.1 3.7 12.1 2.1 1.5 14.2 17.3 7.9 2.4 26.6 17.4 5.2 1.6 8.8 69.0 19.8 125.4 84.1 71.5 70.7 1.7 32.5 104.6 17.0 23.5 207.5 38.4 21.0 11.8 70.4 33.7 154.5 19.4 26.0 4.6 87.6 67.1 28.2 28.7 30.8 93.8 48.5 26.1 24.0 46.7 26.7 17.5 24.1 2.6 53.8 20.1 151.7 2.7 32.7 54.1 28.8 39.1 41.9 24.2 39.7 32.7 6.1 3.2 71.5 56.1 5.3 54.6 90.6 202.1 54.0 10.3 141.4 2.8 0.3 92.1 16.8 37.6 48.5 169.8 16.7 103.6 10.9 26.2 9.6 33.8 5.0 6.8 12.1 25.0 4.1 5.9 53.5 6.3 32.1 10.2 25.2 15.1 2.8 2.7 2.6 5.1 2.6 2.8 2.8 2.7 3.0 2.7 3.7 2.4 29.2 32.1 25.7 0.7 175.3 803.1 316.2 236.4 415.4 0.2 111.8 82.0 4.7 12.8 129.6 3.7 2.1 120.3 125.3 141.1 0.0 54.7 0.8 463.6 48.8 48.5 133.4 5.5 0.0 67.0 14.7 32.9 168.2 529.8 31.8 11.8 7.9 0.5 89.5 0.0 0.0 146.8 181.0 37.2 363.3 1.1 0.9 140.6 74.7 7.5 142.4 0.3 34.0 0.0 0.2 100.1 123.6 1.2 63.1 265.7 94.7 0.5 101.5 0.7 0.0 10.8 32.0 0.3 19.8 474.5 691.2 315.2 117.0 19.8 122.2 569.2 PMEPA1 "STAG1, TMEPAI" ENSG00000124225 "Prostate transmembrane protein, androgen induced 1" Q969W9 20 57648392-57711536 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 110.8" "Cell type enhanced" "Detected in many" "Ductal cells: 339.6;Muller glia cells: 325.9;Pancreatic endocrine cells: 827.5" "Cancer enhanced" "Detected in all" "prostate cancer: 157.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "naive B-cell: 6.3;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 8 "B-cells: 6.3;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "SiHa: 206.1;U-2 OS: 129.9;U-251 MG: 481.8;WM-115: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072291 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA072291: AB_2686509" "unprognostic (2.72e-3)" "prognostic unfavorable (2.45e-4)" "unprognostic (5.77e-2)" "unprognostic (1.73e-1)" "unprognostic (6.61e-2)" "unprognostic (2.11e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.73e-5)" "unprognostic (5.53e-1)" "unprognostic (1.32e-3)" "unprognostic (7.83e-3)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.87e-7)" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (9.87e-3)" "prognostic unfavorable (7.60e-4)" 50.5 14.5 24.2 14.2 75.5 1.3 25.1 38.8 29.9 94.8 1.8 30.7 6.5 48.4 7.1 7.6 19.9 26.0 29.2 24.0 28.3 16.2 3.8 21.8 7.4 32.9 34.1 14.9 31.3 5.0 13.5 3.9 38.8 110.8 8.4 23.6 30.5 20.6 33.2 18.1 12.6 28.8 27.0 6.6 12.2 5.3 36.1 2.4 13.6 13.6 8.9 13.1 29.6 26.2 32.2 75.4 2.3 3.9 2.4 0.0 0.8 4.9 0.2 1.7 0.8 1.5 97.4 0.2 17.7 7.4 51.8 121.1 1.6 100.8 1.3 1.0 4.1 0.0 23.2 0.1 1.5 0.3 0.8 1.2 55.8 4.4 12.1 16.5 13.0 67.8 0.8 1.2 6.2 66.1 3.8 0.7 9.4 15.0 9.6 0.3 36.0 11.3 24.2 0.0 17.7 13.7 206.1 120.3 15.1 5.6 18.8 4.1 33.1 17.9 129.9 1.9 481.8 5.9 0.8 0.5 8.1 1.1 237.1 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.8 0.2 0.1 6.3 1.8 1.2 0.1 0.0 0.1 23.9 0.5 0.6 24.2 75.5 38.8 29.9 24.0 28.3 32.9 34.1 38.8 27.0 36.1 26.2 59.4 57.7 32.3 4.9 32.7 167.0 143.1 120.6 30.7 59.0 38.0 23.0 23.2 125.8 31.7 11.0 2.1 0.2 27.8 57.3 3.9 339.6 1.2 33.4 88.8 55.6 10.1 0.0 19.1 62.5 4.1 40.5 5.1 80.2 59.8 17.5 24.7 0.5 6.1 1.7 32.7 16.9 14.2 3.5 68.0 2.7 3.1 13.4 32.0 31.9 5.8 325.9 0.0 17.6 9.0 827.5 54.2 21.8 25.3 203.1 6.2 2.7 10.1 11.5 72.3 43.8 155.2 0.2 8.8 10.0 178.4 0.1 17.8 9.1 19.3 87.5 POLB ENSG00000070501 "DNA polymerase beta" P06746 8 42338454-42371808 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 254.5;Late spermatids: 133.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 280.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011616, HPA049104, HPA069013" Enhanced Uncertain Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "CAB011616: AB_731977, HPA049104: AB_2680632, HPA069013: " "unprognostic (1.67e-1)" "unprognostic (2.68e-3)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.46e-4)" "unprognostic (8.49e-2)" "unprognostic (2.64e-2)" "unprognostic (4.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.31e-2)" "unprognostic (1.99e-1)" "unprognostic (4.57e-2)" "unprognostic (4.77e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (4.22e-2)" "prognostic favorable (5.65e-4)" 12.4 17.5 26.6 13.5 27.4 51.3 27.4 82.3 35.5 18.9 24.3 12.3 10.8 12.9 19.7 26.5 13.2 17.4 26.1 28.1 29.0 18.0 33.9 14.2 20.2 27.1 27.8 20.4 16.9 18.8 26.7 11.1 28.9 24.8 13.2 18.0 30.3 11.3 85.3 23.1 10.8 10.6 27.6 17.2 14.0 53.1 30.2 24.8 14.2 70.0 22.2 30.8 18.9 28.9 40.2 23.5 40.6 80.4 21.8 20.7 33.8 25.2 29.3 41.5 37.7 33.1 46.0 36.4 31.1 16.5 43.4 20.0 34.1 29.5 50.3 23.8 36.7 26.5 18.2 45.3 34.1 18.6 280.6 18.8 34.4 30.1 35.4 51.8 32.1 77.2 58.4 22.4 40.3 23.6 78.0 52.6 54.4 48.4 26.7 44.2 40.8 31.4 78.4 32.1 22.7 41.8 29.9 19.9 79.0 41.4 52.5 31.5 17.8 19.1 27.0 48.8 24.6 32.5 58.4 52.2 19.3 39.4 52.2 47.6 15.1 48.1 12.0 18.8 13.3 12.2 12.5 13.0 15.7 11.1 14.1 13.3 63.6 22.2 26.3 84.9 19.3 11.5 26.6 27.4 82.3 35.5 28.1 29.0 27.1 27.8 28.9 27.6 30.2 28.9 13.9 3.2 13.6 6.8 20.2 16.8 30.1 14.2 31.3 2.9 14.3 15.1 21.6 7.2 20.7 7.3 8.4 7.5 51.9 3.1 5.9 11.7 254.5 13.8 7.7 12.5 6.0 7.6 15.8 9.6 7.0 9.7 10.2 9.9 23.4 12.7 8.6 12.7 7.4 6.7 20.3 5.4 4.1 5.7 9.9 133.9 7.2 18.2 7.2 19.7 11.2 8.3 13.4 12.5 16.7 33.6 5.8 3.8 21.9 41.6 4.3 6.8 16.4 4.4 0.0 6.6 12.3 19.4 15.4 27.3 20.0 11.1 16.2 7.8 6.6 31.6 PORCN "DHOF, MG61, por, PORC, PPN" ENSG00000102312 "Porcupine O-acyltransferase" Q9H237 X 48508962-48520814 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 37.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 68.5;Club cells: 44.2;Pancreatic endocrine cells: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 176.9;LHCN-M2: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049215, HPA058413" Enhanced Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA049215: , HPA058413: AB_2683711" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (4.01e-2)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (1.26e-3)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "unprognostic (2.09e-2)" "unprognostic (2.65e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (2.35e-1)" 5.2 37.3 8.7 3.3 8.3 2.9 4.7 7.0 10.6 9.1 4.5 6.3 2.3 7.1 2.1 10.8 5.8 4.6 11.5 11.2 7.0 3.7 1.5 4.6 3.6 7.1 6.6 4.3 3.5 9.8 4.7 2.4 7.2 4.5 1.6 7.4 4.9 11.6 7.6 5.9 3.7 4.6 6.2 4.5 5.2 5.1 7.7 2.3 6.3 3.5 3.3 6.2 7.1 7.8 13.1 15.6 3.8 26.6 15.9 9.4 1.6 3.7 7.7 5.8 3.9 1.8 19.7 1.1 15.9 8.3 6.5 17.3 5.5 176.9 1.8 8.3 1.8 2.2 9.0 3.8 23.4 2.0 22.5 12.2 20.6 16.8 36.0 13.5 5.3 6.4 1.0 12.1 60.8 3.7 2.0 2.8 4.9 4.0 10.4 4.0 4.6 20.5 9.8 5.1 4.2 6.5 30.8 5.9 5.9 2.5 6.7 1.0 3.3 15.0 7.8 36.4 6.8 10.4 6.3 1.5 43.0 4.9 8.7 16.9 5.5 6.8 10.8 4.9 8.5 3.2 7.1 9.0 6.8 3.5 4.7 7.1 1.1 8.4 4.3 3.6 4.9 4.7 8.7 8.3 7.0 10.6 11.2 7.0 7.1 6.6 7.2 6.2 7.7 7.8 5.4 6.4 2.8 5.2 3.8 4.0 5.3 68.5 8.0 15.4 2.9 4.6 3.4 4.3 44.2 16.5 18.8 0.3 7.3 0.8 1.9 6.9 0.2 13.4 3.5 5.7 6.0 1.3 7.8 9.9 1.3 5.0 3.6 17.8 5.7 3.9 5.0 0.7 3.5 8.4 7.6 2.9 12.2 2.7 4.5 0.1 5.6 2.5 3.6 2.8 3.1 10.1 10.3 6.0 2.8 36.4 1.8 4.1 6.3 2.5 0.2 0.7 8.7 15.5 6.6 4.0 4.8 2.9 4.9 4.2 3.8 8.2 6.9 7.5 1.5 6.6 PPA1 "IOPPP, PP, PP1, Ppase, SID6-8061" ENSG00000180817 "Inorganic pyrophosphatase 1" Q15181 10 70202835-70233911 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 1239.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019878, HPA020096" Supported Supported Vesicles NA NA 1000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA019878: AB_1855601, HPA020096: AB_1855600" "unprognostic (1.50e-1)" "unprognostic (2.85e-1)" "unprognostic (4.71e-2)" "unprognostic (2.85e-1)" "unprognostic (1.42e-1)" "unprognostic (4.47e-2)" "unprognostic (2.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.34e-1)" "unprognostic (1.62e-1)" "unprognostic (2.13e-2)" "unprognostic (3.60e-2)" "unprognostic (1.82e-3)" "unprognostic (5.36e-2)" "unprognostic (2.37e-1)" "unprognostic (3.53e-2)" "unprognostic (2.74e-1)" 176.7 198.5 124.3 116.0 138.8 85.0 186.7 166.7 163.0 96.5 123.0 137.3 99.4 85.8 166.7 157.7 110.2 90.3 100.1 125.8 148.5 123.2 150.2 129.0 132.6 153.1 142.3 56.5 188.5 68.5 92.1 103.7 165.4 68.7 152.5 332.0 116.1 78.7 133.0 85.9 125.1 96.8 159.3 64.2 97.5 73.5 141.6 103.5 126.3 137.3 137.3 167.1 140.0 167.0 446.9 181.2 158.8 471.2 421.6 368.8 148.2 163.5 305.3 250.1 261.8 556.7 230.6 641.0 144.5 164.0 162.8 351.2 470.7 318.4 253.8 599.1 443.5 176.1 169.1 321.7 265.8 439.0 106.9 244.2 372.9 201.3 530.7 273.8 307.9 319.2 416.9 336.4 239.4 262.3 426.5 408.7 165.9 614.2 494.8 256.9 181.7 378.2 527.0 276.3 474.4 159.6 179.3 694.5 148.0 110.8 174.3 194.2 141.0 69.0 262.2 229.4 315.2 110.1 259.2 469.8 106.7 605.2 62.0 0.4 68.8 1.7 48.9 55.2 131.1 83.6 112.3 85.6 190.0 59.4 122.7 106.8 4.1 65.8 63.1 44.4 120.4 105.3 124.3 138.8 166.7 163.0 125.8 148.5 153.1 142.3 165.4 159.3 141.6 167.0 207.0 224.4 165.9 17.0 122.7 267.9 366.2 427.3 158.2 184.9 347.8 363.7 93.3 218.8 275.7 108.5 173.0 313.2 63.4 203.3 201.5 540.1 31.7 278.8 196.1 182.1 162.7 88.4 36.8 776.1 298.3 156.9 114.2 512.1 36.8 208.2 38.2 141.8 96.5 85.8 41.2 254.9 160.7 80.1 148.1 31.7 109.6 120.3 181.5 29.0 612.7 1239.0 65.9 21.6 98.4 532.9 213.5 117.4 161.2 512.4 444.5 551.2 92.1 278.4 65.7 97.2 136.8 173.7 170.7 245.8 257.1 245.7 120.9 203.0 347.6 613.9 PPIP5K2 "CFAP160, DFNB100, HISPPD1, KIAA0433, VIP2" ENSG00000145725 "Diphosphoinositol pentakisphosphate kinase 2" O43314 5 103120149-103212799 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hearing "Kinase, Transferase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 160.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037895, HPA038442" Approved Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA037895: AB_2675724, HPA038442: AB_10673173" "unprognostic (2.18e-1)" "unprognostic (1.04e-1)" "unprognostic (2.36e-2)" "unprognostic (1.93e-1)" "unprognostic (8.83e-2)" "unprognostic (1.60e-3)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (1.60e-2)" "unprognostic (8.59e-3)" "unprognostic (1.39e-1)" "unprognostic (2.12e-1)" "unprognostic (4.32e-2)" "unprognostic (1.29e-1)" "unprognostic (4.06e-1)" "prognostic unfavorable (1.12e-4)" "unprognostic (8.80e-2)" 15.7 19.1 6.8 22.0 7.9 51.6 25.1 18.9 13.9 22.2 5.8 28.1 18.3 20.6 21.2 17.1 14.5 20.4 19.5 6.7 8.9 20.3 29.2 16.2 25.5 15.4 11.9 26.1 26.7 23.0 18.1 16.7 15.1 16.3 25.5 19.2 17.1 15.4 4.2 17.2 16.5 18.4 6.1 23.9 22.5 15.1 7.3 27.9 23.3 7.7 24.5 17.8 13.9 10.7 27.4 25.3 50.8 65.2 40.8 53.4 47.8 63.5 39.3 34.2 47.6 20.9 48.3 67.6 56.2 60.9 52.7 16.5 43.9 33.2 57.5 53.7 23.5 84.7 44.3 33.4 29.0 72.1 70.4 34.5 23.4 52.0 46.1 31.2 40.0 42.5 84.9 57.0 53.1 21.3 60.9 44.6 55.4 12.7 64.4 58.6 46.7 89.3 36.8 31.5 29.6 40.1 43.5 39.9 40.7 34.0 33.5 48.9 42.7 55.8 25.7 56.0 45.1 38.1 87.3 91.3 31.5 116.0 51.2 41.7 21.5 39.6 13.0 22.9 15.8 19.5 12.6 14.2 25.6 16.1 16.1 17.0 19.7 17.8 32.4 15.5 12.3 11.1 6.8 7.9 18.9 13.9 6.7 8.9 15.4 11.9 15.1 6.1 7.3 10.7 35.8 48.1 23.1 49.3 39.3 13.6 12.8 13.7 31.9 38.5 26.1 26.4 48.9 18.6 29.6 16.5 45.9 12.7 35.7 29.7 5.9 11.6 5.6 25.4 44.7 28.7 16.3 70.7 88.4 17.0 19.2 33.0 33.6 30.6 43.6 49.2 14.6 20.6 30.6 16.8 160.3 24.2 16.2 39.5 22.4 6.7 29.5 43.3 12.4 49.6 47.5 14.5 27.8 62.8 67.0 16.9 19.1 23.7 56.6 12.1 13.3 22.6 25.1 25.2 6.6 30.3 28.1 39.7 21.6 31.6 15.8 26.0 31.6 38.7 30.1 12.6 PPM1J "DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ" ENSG00000155367 "Protein phosphatase, Mg2+/Mn2+ dependent 1J" Q5JR12 1 112709994-112715477 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "epididymis: 18.8;skeletal muscle: 68.4;skin 1: 18.1;testis: 63.8;tongue: 25.6" "Group enriched" "Detected in many" 4 "Early spermatids: 123.6;Late spermatids: 281.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 67.9" "Lineage enriched" "Detected in many" 15 "dendritic cells: 67.9" "Cell line enhanced" "Detected in many" "T-47d: 19.5" "Region enriched" "Detected in many" 7 "olfactory bulb: 27.3" "Low region specificity" "Detected in all" HPA046045 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 6: T47d - Mammary gland" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA046045: AB_2679516" "unprognostic (8.68e-2)" "unprognostic (5.65e-2)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "unprognostic (2.93e-3)" "unprognostic (2.34e-2)" "unprognostic (3.55e-2)" "unprognostic (3.74e-2)" "unprognostic (2.55e-1)" "unprognostic (9.30e-3)" "unprognostic (3.36e-2)" "unprognostic (7.22e-2)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (1.46e-1)" "unprognostic (2.28e-2)" "unprognostic (9.96e-4)" 1.1 2.6 6.3 1.0 6.6 0.7 2.2 5.9 6.5 2.3 3.8 1.2 0.6 1.9 18.8 4.6 2.8 1.0 8.7 5.8 5.7 7.8 0.7 1.6 3.3 5.2 7.8 2.3 1.7 5.5 2.6 0.5 4.6 3.3 0.6 6.9 2.8 2.1 68.4 18.1 1.4 1.3 4.5 1.4 1.2 63.8 9.1 2.3 3.1 25.6 2.2 1.1 4.0 3.9 2.7 0.1 1.5 1.7 0.8 1.5 1.1 0.3 0.7 0.3 1.0 1.2 0.8 0.4 0.4 0.8 0.8 4.9 1.1 4.6 0.4 0.0 2.6 0.8 0.2 0.2 0.9 0.0 0.2 1.7 3.0 0.9 4.6 1.0 2.1 0.2 1.0 0.0 1.2 2.9 0.0 0.0 1.6 1.4 2.3 0.1 0.1 0.0 2.7 0.1 0.8 0.2 0.6 4.3 1.3 2.2 19.5 0.0 1.1 0.3 2.8 0.0 0.2 0.1 0.0 0.0 2.3 0.6 2.6 0.0 0.3 0.0 0.0 1.5 0.1 0.7 0.0 0.1 7.1 0.7 0.0 0.0 0.0 0.0 4.3 67.9 0.0 0.8 6.3 6.6 5.9 6.5 5.8 5.7 5.2 7.8 4.6 4.5 9.1 3.9 1.2 0.0 0.5 0.3 2.0 2.2 4.7 8.7 10.2 5.7 4.2 4.6 5.8 0.0 2.7 1.8 10.4 1.0 41.3 0.7 9.8 3.2 123.6 3.2 0.3 1.5 0.0 0.0 1.8 4.3 1.4 1.1 1.1 0.6 0.0 5.6 0.7 0.1 0.7 0.0 1.5 0.9 2.0 1.3 11.5 281.6 3.1 2.0 0.0 0.0 1.6 25.4 0.0 0.0 0.2 2.1 2.4 2.6 0.0 6.7 0.3 0.6 1.8 9.1 6.6 1.1 2.8 2.8 16.9 3.5 2.8 0.5 0.9 3.2 0.8 2.9 PPM1N FLJ40125 ENSG00000213889 "Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)" Q8N819 19 45488777-45502510 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 8 "skeletal muscle: 213.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 123.1;Rod photoreceptor cells: 74.3" "Cancer enhanced" "Detected in many" "testis cancer: 11.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "non-classical monocyte: 142.4" "Lineage enriched" "Detected in all" 11 "monocytes: 142.4" "Cell line enhanced" "Detected in many" "OE19: 24.1;RT4: 29.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043577 Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA043577: " "unprognostic (2.38e-2)" "unprognostic (1.11e-2)" "unprognostic (8.53e-2)" "unprognostic (6.59e-2)" "unprognostic (4.71e-1)" "unprognostic (2.64e-2)" "unprognostic (1.98e-3)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "unprognostic (4.45e-2)" "unprognostic (9.27e-2)" "unprognostic (2.48e-2)" "unprognostic (1.11e-16)" "unprognostic (3.42e-2)" "unprognostic (1.79e-1)" "unprognostic (3.92e-2)" "unprognostic (1.86e-3)" 2.0 0.8 15.5 2.0 14.7 2.6 3.3 14.5 19.9 2.0 14.5 2.6 0.6 0.7 1.3 2.6 0.9 1.4 1.3 15.1 15.0 1.4 2.6 2.5 3.0 14.7 14.7 0.6 0.5 2.1 1.1 4.7 15.1 1.2 1.3 25.8 0.9 2.0 213.3 3.1 1.6 1.2 13.7 9.2 2.8 5.3 14.3 2.3 1.1 0.2 3.4 2.4 1.6 16.2 2.6 7.1 1.2 5.1 5.9 7.8 14.7 1.9 3.0 0.6 2.3 1.7 15.8 11.1 3.2 1.8 4.1 7.6 3.0 2.2 0.9 10.9 4.5 9.0 2.7 1.9 1.4 0.8 18.1 3.2 3.6 3.1 1.9 4.0 1.0 4.4 10.3 9.6 1.0 1.9 3.1 4.6 4.0 24.1 1.4 2.0 1.5 3.0 3.4 29.9 5.8 6.8 1.0 11.1 9.2 8.8 3.8 2.7 1.5 8.2 4.7 4.3 1.4 1.7 4.5 2.3 6.1 2.3 7.2 6.7 4.4 3.2 6.4 22.5 5.5 6.3 3.9 6.2 12.8 3.6 4.3 7.9 6.5 3.1 142.4 2.4 4.5 5.7 15.5 14.7 14.5 19.9 15.1 15.0 14.7 14.7 15.1 13.7 14.3 16.2 6.4 0.0 2.7 1.0 7.5 3.4 14.7 6.2 17.6 14.1 5.9 32.5 2.3 17.2 2.5 3.7 31.3 3.2 6.0 5.5 0.0 2.9 12.5 2.0 3.9 3.5 3.0 0.8 1.1 1.8 123.1 6.5 3.1 7.4 7.0 1.0 5.3 1.3 20.1 1.7 1.4 4.2 0.0 15.5 15.7 4.9 0.9 15.2 1.8 1.0 6.1 7.3 20.6 0.0 0.3 3.1 4.7 0.7 1.7 6.7 6.9 0.6 0.8 74.3 0.0 25.6 5.5 2.9 9.1 3.4 4.1 8.5 7.5 0.3 3.1 8.4 PPP1R11 "CFAP255, HCG-V, HCGV, TCTE5, Tctex5" ENSG00000204619 "Protein phosphatase 1 regulatory inhibitor subunit 11" O60927 6 30066709-30070333 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Late spermatids: 696.0" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 8 "cerebral cortex: 8.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 51.5;AN3-CA: 65.6;fHDF/TERT166: 48.6;GAMG: 47.4;HBEC3-KT: 53.6;JURKAT: 76.7;RPTEC TERT1: 47.4;U-266/84: 64.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043266, HPA060174" Approved Approved Vesicles NA NA 43000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA043266: AB_2678400, HPA060174: AB_2684216" "unprognostic (2.00e-2)" "unprognostic (1.10e-1)" "unprognostic (8.88e-2)" "unprognostic (4.24e-2)" "unprognostic (3.45e-1)" "unprognostic (1.05e-1)" "unprognostic (1.77e-2)" "unprognostic (1.18e-1)" "unprognostic (2.81e-1)" "unprognostic (1.74e-3)" "unprognostic (3.33e-2)" "unprognostic (2.68e-1)" "unprognostic (8.36e-3)" "unprognostic (1.74e-1)" "unprognostic (3.31e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-3)" 44.5 41.1 0.7 0.0 0.7 1.9 41.4 0.6 8.8 44.4 0.6 55.5 11.6 49.6 33.1 52.1 37.3 11.8 51.0 0.7 0.7 62.3 47.5 43.7 5.4 0.9 0.7 41.8 45.1 2.2 29.2 5.8 0.8 46.3 0.7 7.9 42.8 0.0 50.4 42.9 50.7 0.0 0.6 39.8 59.5 41.5 0.7 9.7 42.3 0.0 11.8 51.6 42.7 1.1 51.5 0.0 0.0 65.6 29.4 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 48.6 47.4 0.0 0.0 53.6 0.0 1.0 34.5 42.6 0.0 0.0 0.0 3.0 3.9 0.0 0.0 0.0 0.7 0.0 0.0 76.7 0.5 2.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.4 47.4 29.0 0.0 0.0 0.7 35.5 4.8 26.8 0.0 0.0 0.0 0.0 0.3 4.1 1.5 30.7 64.9 26.7 0.7 0.0 0.0 11.5 4.1 12.4 4.7 9.3 4.5 6.8 5.3 6.5 2.2 7.2 4.9 7.0 2.8 3.9 7.9 3.2 8.4 6.8 0.7 0.7 0.6 8.8 0.7 0.7 0.9 0.7 0.8 0.6 0.7 1.1 38.2 19.2 20.2 2.6 57.8 52.8 80.0 77.2 29.0 29.3 47.7 32.8 18.8 52.9 49.7 40.5 6.2 56.0 39.2 111.5 95.9 142.2 242.1 19.8 24.2 44.3 53.7 32.4 10.1 136.3 119.9 27.0 53.5 31.8 78.6 21.4 45.7 28.0 65.7 13.5 9.0 83.8 77.3 49.7 53.8 696.0 32.3 43.5 62.2 3.7 75.4 58.4 92.7 6.0 7.6 136.5 114.1 40.3 42.2 66.6 139.6 93.3 38.7 33.1 39.5 27.2 89.4 61.9 23.2 39.0 66.5 75.2 52.4 16.5 51.8 94.9 PPP1R15A GADD34 ENSG00000087074 "Protein phosphatase 1 regulatory subunit 15A" O75807 19 48872421-48876058 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Stress response, Translation regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 575.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 340.1" "Group enriched" "Detected in all" 5 "dendritic cells: 114.6;granulocytes: 340.1" "Cell line enhanced" "Detected in all" "HHSteC: 282.8;hTERT-HME1: 493.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018395, HPA020240" Approved Uncertain Vesicles NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Vesicles "CAB018395: AB_2237473, HPA020240: AB_1849404" "unprognostic (2.43e-3)" "unprognostic (3.21e-1)" "unprognostic (7.75e-2)" "unprognostic (1.17e-3)" "unprognostic (2.22e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (5.46e-2)" "unprognostic (2.66e-2)" "unprognostic (7.16e-3)" "unprognostic (5.40e-2)" "unprognostic (1.52e-1)" "unprognostic (2.22e-1)" "unprognostic (6.43e-3)" "unprognostic (1.49e-1)" "unprognostic (1.29e-2)" "unprognostic (6.94e-2)" 199.1 84.7 33.3 49.5 37.4 575.6 97.7 45.9 54.1 99.5 66.9 78.9 36.0 70.1 11.3 98.3 147.4 82.0 185.6 34.8 36.2 95.0 85.1 226.7 33.1 44.8 32.7 101.2 33.4 23.1 65.0 74.8 42.9 60.5 45.5 10.9 41.6 38.6 88.5 191.5 58.8 101.8 29.4 69.0 90.7 23.3 38.7 52.0 69.4 60.6 20.2 110.6 108.4 46.9 55.8 23.7 24.9 20.5 71.2 40.4 39.3 95.1 148.0 106.5 95.9 36.5 27.6 19.1 25.0 69.0 145.5 39.4 9.3 49.7 79.8 10.7 14.4 86.4 14.4 18.1 282.8 20.2 119.2 55.1 135.5 147.0 493.7 48.0 56.3 21.5 118.2 155.6 69.5 6.1 11.1 27.9 6.2 100.3 42.3 12.6 23.1 6.5 22.3 63.8 14.2 24.3 49.2 33.2 230.2 26.0 11.9 36.1 60.6 126.3 31.8 89.3 58.5 82.8 72.1 17.9 46.2 13.7 154.8 161.8 49.4 91.3 22.5 31.1 19.6 36.7 22.2 18.7 35.9 29.7 12.3 11.0 340.1 13.8 37.6 114.6 31.5 36.9 33.3 37.4 45.9 54.1 34.8 36.2 44.8 32.7 42.9 29.4 38.7 46.9 499.1 288.4 225.1 2.3 387.2 482.2 989.5 232.0 730.1 25.0 294.3 220.7 173.3 127.2 204.3 12.9 35.5 104.8 290.3 435.6 3.9 224.0 4.6 619.6 427.4 370.4 170.9 213.5 4.1 94.5 219.0 466.3 430.7 1063.2 708.1 53.3 150.0 14.4 195.0 35.3 4.1 354.1 140.4 146.7 904.4 5.1 58.7 615.3 396.6 9.4 105.1 50.5 20.6 1.0 2.0 233.4 421.8 23.0 477.1 731.5 348.7 9.0 246.2 27.7 85.5 483.5 612.1 7.0 9.5 573.1 431.0 288.4 427.9 102.8 321.8 733.9 PPP3CC "CALNA3, PP2Bgamma" ENSG00000120910 "Protein phosphatase 3 catalytic subunit gamma" P48454 8 22440819-22541142 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 145.8;Spermatocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023396, CAB024950" Approved Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Vesicles "CAB024950: , HPA023396: AB_1855663" "unprognostic (7.66e-3)" "unprognostic (1.61e-2)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (1.38e-1)" "unprognostic (2.21e-2)" "unprognostic (7.71e-2)" "prognostic favorable (6.80e-5)" "unprognostic (9.25e-2)" "unprognostic (1.97e-1)" "unprognostic (8.84e-2)" "unprognostic (4.05e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (4.00e-1)" "unprognostic (2.78e-2)" "unprognostic (1.64e-2)" 28.5 11.9 11.8 16.5 11.8 26.5 20.8 17.7 15.3 18.1 31.1 16.6 9.1 14.5 10.6 16.9 15.6 15.7 34.5 11.3 10.8 12.9 12.4 21.5 33.0 12.1 11.0 14.0 14.3 18.4 11.7 19.3 12.2 14.4 10.3 77.9 14.0 8.2 89.4 13.6 15.4 15.5 10.0 22.4 14.6 56.0 13.1 15.0 16.6 54.2 26.9 17.0 16.4 14.8 12.2 8.8 7.7 9.4 19.8 24.4 11.2 16.5 28.9 23.9 26.5 5.1 7.5 45.7 19.7 25.6 40.0 8.4 17.9 16.5 30.5 26.3 9.5 9.8 10.5 14.7 26.8 7.1 15.6 15.0 22.3 16.2 16.5 25.6 21.1 22.0 19.6 58.8 27.2 5.7 16.8 11.7 5.6 12.5 12.0 54.0 18.1 15.2 22.4 11.3 5.4 12.7 12.3 7.4 17.4 14.4 4.9 11.8 22.8 37.1 7.9 56.7 12.9 29.3 38.5 48.3 19.6 9.3 25.1 5.4 2.7 10.7 16.6 3.2 12.7 26.3 19.0 23.6 5.1 21.3 18.1 14.9 0.6 19.2 4.7 6.2 17.2 7.1 11.8 11.8 17.7 15.3 11.3 10.8 12.1 11.0 12.2 10.0 13.1 14.8 27.2 6.4 5.1 49.6 74.7 16.6 21.3 32.6 12.0 12.8 10.0 6.0 8.0 14.3 14.0 7.3 47.9 18.0 50.3 6.7 7.9 15.0 145.8 6.5 12.7 24.2 10.3 10.8 78.9 21.0 23.8 25.1 6.6 14.6 3.8 3.9 23.6 7.8 13.1 3.3 83.6 2.5 38.7 10.8 24.6 22.6 22.4 19.3 28.4 76.8 30.4 13.1 59.8 99.5 64.8 21.1 7.4 21.4 96.8 26.3 10.6 11.6 7.8 50.5 32.9 19.5 23.3 131.8 29.6 17.1 11.4 14.1 53.4 4.8 6.3 25.5 PPT2 ENSG00000221988 "Palmitoyl-protein thioesterase 2" Q9UMR5 6 32153441-32163678 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 33.6;Smooth muscle cells: 27.8;Syncytiotrophoblasts: 23.3" "Cancer enhanced" "Detected in all" "melanoma: 21.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 21.3;HEK 293: 27.9;SK-MEL-30: 29.4" HPA000414 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA000414: " "unprognostic (1.90e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.03e-5)" "unprognostic (1.62e-1)" "unprognostic (6.75e-3)" "unprognostic (2.92e-3)" "unprognostic (6.41e-3)" "unprognostic (7.12e-2)" "unprognostic (2.56e-3)" "unprognostic (5.28e-3)" "unprognostic (1.12e-2)" "unprognostic (2.75e-3)" "unprognostic (5.09e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.24e-3)" 19.0 18.0 1.1 2.1 1.1 0.1 18.7 1.1 4.8 26.5 1.0 23.7 1.6 22.0 2.6 28.2 21.7 0.0 24.5 1.1 1.1 22.1 13.9 14.3 1.7 1.1 1.2 46.2 14.3 0.0 13.7 3.9 1.1 17.2 1.5 6.2 14.9 0.0 19.0 29.4 14.9 1.3 1.1 13.3 21.0 8.3 1.1 1.9 14.6 0.2 1.0 18.1 24.2 1.3 0.0 0.0 0.0 0.4 21.3 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.2 1.6 0.7 5.3 2.6 5.0 0.0 0.0 27.9 4.0 0.0 0.0 0.0 3.5 1.8 4.0 1.6 0.0 7.3 3.8 0.0 14.9 0.0 1.8 1.7 13.0 4.6 0.0 0.0 0.9 0.0 6.3 5.8 0.0 14.3 0.0 1.6 5.4 8.7 5.2 29.4 15.2 0.0 3.7 0.8 0.0 11.4 0.0 0.0 0.8 12.6 3.0 5.8 2.2 3.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.7 0.0 0.1 1.1 1.1 1.1 4.8 1.1 1.1 1.1 1.2 1.1 1.1 1.1 1.3 9.4 0.0 0.5 0.0 0.7 3.3 2.9 2.6 5.7 12.4 4.2 2.9 6.8 2.8 2.8 3.7 16.7 14.5 4.4 2.4 1.9 1.8 0.3 4.5 4.3 7.6 4.9 17.4 0.0 3.0 9.2 6.3 1.5 5.0 0.0 33.6 6.4 4.4 3.0 3.3 0.0 2.6 2.0 1.3 1.3 1.1 4.1 1.1 7.2 0.0 0.2 9.5 3.1 0.0 0.0 1.8 3.8 3.0 1.7 1.4 1.4 3.1 0.6 6.1 0.0 3.6 27.8 4.0 6.7 4.4 2.3 23.3 1.4 5.0 3.0 1.5 PRCP "HUMPCP, PCP" ENSG00000137509 Prolylcarboxypeptidase P42785 11 82822936-82970584 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 348.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 463.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017065, HPA071115" Approved Supported Vesicles "Intracellular and membrane" NA NA 42000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA017065: AB_1855676, HPA071115: " "unprognostic (3.24e-1)" "unprognostic (2.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (2.54e-1)" "unprognostic (1.33e-2)" "unprognostic (9.22e-2)" "unprognostic (1.42e-1)" "unprognostic (7.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.70e-1)" "unprognostic (1.88e-2)" "prognostic favorable (2.65e-6)" "unprognostic (7.16e-2)" "unprognostic (1.73e-2)" "unprognostic (3.49e-1)" "unprognostic (4.07e-1)" 74.8 87.3 81.1 57.8 82.1 37.7 70.0 84.3 109.1 91.9 95.0 49.3 28.6 62.9 81.4 62.1 57.0 64.3 70.0 76.6 85.6 144.7 151.9 58.1 92.1 84.4 82.1 53.5 37.9 78.4 34.5 152.8 80.9 52.5 46.6 21.9 85.6 55.5 15.9 54.1 31.8 80.8 89.0 54.0 32.0 41.8 86.0 33.7 63.7 28.5 85.0 100.2 57.5 86.7 34.9 41.8 49.6 121.0 463.5 146.7 67.1 67.5 131.9 70.9 97.0 103.5 70.7 55.9 100.7 117.9 72.6 53.2 53.7 45.2 72.0 43.9 38.3 37.7 56.5 76.7 86.2 31.0 124.7 122.0 39.3 72.7 68.6 166.5 224.0 26.3 39.1 69.8 72.7 19.5 4.9 171.7 33.9 90.3 31.1 27.1 97.0 65.1 118.0 71.2 24.0 51.9 101.9 60.2 41.5 80.6 66.6 49.6 65.0 78.8 77.4 71.1 33.5 64.2 113.6 46.3 32.9 41.7 44.5 53.5 76.9 50.9 13.7 79.0 16.1 31.7 14.0 15.9 140.2 34.2 12.0 17.4 89.0 34.7 64.8 27.9 14.8 49.6 81.1 82.1 84.3 109.1 76.6 85.6 84.4 82.1 80.9 89.0 86.0 86.7 86.9 19.2 12.9 58.8 45.5 31.4 41.5 53.4 25.0 11.7 26.2 25.1 26.6 37.1 25.2 62.5 2.1 65.1 29.0 9.8 29.4 32.9 44.9 17.4 37.7 180.4 19.7 13.7 42.2 12.0 120.1 73.6 23.9 29.9 12.7 18.2 348.7 65.4 80.7 16.8 38.5 19.1 14.2 152.9 118.9 47.6 44.1 88.0 71.2 33.7 79.5 53.5 28.8 34.7 10.5 8.2 10.2 46.3 62.2 23.3 3.9 83.8 9.1 5.3 65.7 25.5 25.6 60.8 6.3 54.3 34.9 52.9 22.3 27.7 20.9 39.2 PRPS1 "CMTX5, DFN2, DFNX1" ENSG00000147224 "Phosphoribosyl pyrophosphate synthetase 1" P60891 X 107628428-107651993 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Gout, Mental retardation, Neurodegeneration, Neuropathy, Non-syndromic deafness, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043760, HPA051269" Uncertain Approved Vesicles NA NA 320000 "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA043760: AB_2678656, HPA051269: " "unprognostic (4.47e-2)" "unprognostic (6.18e-2)" "unprognostic (2.57e-2)" "unprognostic (4.19e-3)" "unprognostic (2.30e-3)" "unprognostic (2.56e-3)" "unprognostic (3.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.46e-1)" "unprognostic (9.73e-2)" "unprognostic (1.91e-2)" "unprognostic (4.11e-2)" "unprognostic (2.85e-2)" "unprognostic (4.57e-2)" "unprognostic (1.29e-1)" "unprognostic (1.25e-2)" "unprognostic (5.25e-2)" 22.9 28.0 33.7 30.2 35.0 58.0 21.0 32.4 36.4 20.0 59.3 19.0 11.0 23.7 14.8 13.7 25.9 13.9 22.2 33.7 39.6 27.6 51.5 21.5 42.7 35.4 39.1 30.2 21.7 27.2 23.2 14.6 37.6 21.3 17.9 30.2 16.3 17.4 49.1 12.3 16.7 29.5 34.2 26.2 15.5 13.4 35.2 52.0 44.1 37.9 45.7 23.6 15.2 34.4 93.5 128.9 56.4 69.9 32.7 26.5 18.6 253.2 55.8 146.0 122.6 55.5 36.6 156.9 111.7 94.9 104.1 36.6 176.0 53.8 148.3 79.9 150.9 84.2 140.0 100.3 28.8 153.1 55.6 28.2 30.6 90.2 56.2 96.7 52.3 108.2 137.4 183.5 69.0 51.0 101.2 113.6 213.5 77.2 141.4 117.6 96.3 125.4 60.7 54.2 96.2 52.5 131.5 77.6 57.3 106.4 36.0 61.7 31.2 93.2 45.0 108.3 109.1 61.8 115.1 172.7 50.1 163.6 61.6 8.8 8.9 22.6 26.0 14.3 30.8 29.3 31.7 32.2 11.4 31.0 36.1 30.7 4.7 28.5 15.7 16.3 35.5 21.1 33.7 35.0 32.4 36.4 33.7 39.6 35.4 39.1 37.6 34.2 35.2 34.4 21.0 6.4 10.0 4.6 44.2 31.1 18.4 13.2 12.0 28.4 8.3 9.4 12.1 15.7 12.6 16.5 4.2 8.8 29.3 3.0 25.4 18.3 1.2 11.5 13.3 18.1 16.2 52.2 4.8 20.2 11.5 22.2 10.2 5.7 26.6 13.2 14.6 57.5 35.3 15.2 10.0 6.5 6.1 18.6 34.8 3.9 14.0 16.8 26.6 6.5 24.9 20.0 27.8 3.5 4.8 19.1 3.7 17.0 35.7 16.2 1.5 29.4 27.1 14.1 0.0 18.1 30.7 3.6 10.9 10.8 22.3 1.8 45.0 19.7 8.0 9.7 PRPS1L1 "PRPS3, PRPSL" ENSG00000229937 "Phosphoribosyl pyrophosphate synthetase 1 like 1" P21108 7 18026770-18027846 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 315 "testis: 31.5" "Group enriched" "Detected in some" 7 "Early spermatids: 71.0;Spermatocytes: 129.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051269 Uncertain Vesicles NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA051269: " "unprognostic (2.39e-2)" "unprognostic (3.18e-2)" "unprognostic (1.11e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 6.6 0.0 1.1 129.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRRC1 FLJ32875 ENSG00000164244 "Proline rich coiled-coil 1" Q96M27 5 127517640-127555085 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039212 Supported Approved Vesicles NA NA 170000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA039212: AB_10794634" "prognostic unfavorable (9.35e-5)" "unprognostic (9.01e-2)" "unprognostic (5.26e-3)" "unprognostic (6.36e-2)" "unprognostic (2.95e-1)" "unprognostic (4.47e-2)" "unprognostic (4.21e-2)" "unprognostic (1.39e-1)" "unprognostic (6.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.74e-3)" "unprognostic (5.53e-2)" "unprognostic (3.20e-3)" "unprognostic (1.57e-1)" "unprognostic (2.83e-1)" "unprognostic (3.45e-3)" "unprognostic (2.19e-1)" 17.3 18.7 7.0 18.1 8.1 21.2 24.2 8.3 9.3 27.5 12.4 23.5 25.3 22.0 23.4 20.2 15.9 17.1 14.5 6.5 7.6 21.4 26.7 18.2 17.9 7.9 8.0 22.3 32.1 30.4 19.1 27.0 8.6 21.1 27.2 11.5 25.6 18.0 12.9 19.2 24.4 22.4 7.8 16.2 24.0 13.2 7.5 19.5 26.6 10.2 20.9 19.4 17.3 9.9 30.3 30.5 44.5 34.0 58.8 75.1 51.9 52.3 58.4 45.7 71.8 52.4 34.6 33.6 53.2 83.6 34.4 26.9 35.0 64.8 70.6 46.7 24.4 29.3 29.1 45.6 33.8 27.4 36.9 51.5 46.7 48.5 56.3 41.9 49.4 31.6 25.5 40.2 53.4 34.2 53.9 29.4 25.5 43.5 39.5 20.5 58.9 43.8 36.4 37.6 32.4 25.0 41.0 44.1 40.1 40.6 47.2 35.3 58.9 41.8 31.2 49.3 37.2 33.5 26.8 43.6 49.3 42.9 42.0 18.7 11.7 9.4 18.6 13.5 22.6 15.4 15.1 16.0 15.6 11.2 16.5 14.9 3.6 12.7 13.5 10.4 13.0 12.3 7.0 8.1 8.3 9.3 6.5 7.6 7.9 8.0 8.6 7.8 7.5 9.9 16.3 35.3 25.5 9.8 17.8 14.7 14.0 37.2 22.8 12.8 24.1 15.0 12.5 27.1 40.6 27.6 14.6 25.5 14.0 38.2 13.7 30.5 3.8 16.2 33.6 22.8 15.6 12.4 13.5 30.9 42.2 30.8 28.5 23.2 15.8 28.7 26.0 37.3 21.7 8.4 13.5 50.2 28.5 20.2 7.6 4.8 34.5 14.7 19.6 15.9 17.8 10.7 22.6 18.6 25.1 31.8 25.1 30.1 38.0 26.6 34.1 28.0 30.0 12.7 13.1 18.8 26.4 13.6 21.2 18.2 18.6 31.6 19.3 21.7 33.6 26.0 PRSS27 "CAPH2, MPN" ENSG00000172382 "Serine protease 27" Q9BQR3 16 2712419-2720551 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.5;esophagus: 388.6;vagina: 134.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Horizontal cells: 11.8;Squamous epithelial cells: 9.6;Urothelial cells: 11.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 6.1;SK-BR-3: 24.4;T-47d: 14.6;U-266/70: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB024920, HPA028848" Approved Approved Vesicles "Secreted to digestive system" NA NA 8700000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB024920: , HPA028848: " "unprognostic (2.10e-2)" "unprognostic (2.15e-1)" "unprognostic (3.46e-3)" "unprognostic (5.35e-2)" "unprognostic (5.25e-2)" "unprognostic (2.48e-2)" "unprognostic (2.56e-1)" "unprognostic (3.12e-1)" "unprognostic (4.66e-1)" "unprognostic (1.08e-1)" "unprognostic (3.79e-2)" "unprognostic (4.40e-3)" "unprognostic (4.03e-3)" "unprognostic (2.40e-1)" "unprognostic (2.26e-1)" "unprognostic (2.04e-2)" "unprognostic (1.28e-2)" 1.0 0.4 0.9 0.2 0.9 0.3 1.3 1.0 2.0 83.5 0.6 1.0 0.0 1.0 0.0 388.6 0.7 0.2 0.4 0.8 1.4 1.1 0.6 0.6 0.3 1.2 1.5 0.5 0.8 0.7 1.5 0.1 1.0 1.0 0.0 0.2 52.5 0.4 0.3 3.3 0.6 0.0 1.0 0.6 0.8 2.6 1.2 0.6 0.8 0.0 29.9 0.8 134.2 0.9 0.1 0.3 0.4 2.1 0.3 0.7 6.1 0.0 0.2 0.2 0.2 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.5 0.1 0.1 0.0 1.0 0.0 0.3 1.2 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.6 0.0 2.0 0.0 1.1 1.4 0.2 0.0 1.0 0.2 0.1 0.2 0.3 0.7 2.8 0.0 24.4 0.6 0.1 14.6 1.8 0.0 0.4 0.0 0.1 0.0 5.2 3.7 0.5 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.9 1.0 2.0 0.8 1.4 1.2 1.5 1.0 1.0 1.2 0.9 1.5 9.6 5.8 0.0 0.5 1.8 2.5 1.3 0.6 5.2 5.1 6.2 1.2 1.5 5.6 1.8 4.2 0.7 0.5 1.2 0.0 1.5 3.3 0.6 1.4 1.8 0.0 0.0 0.4 1.4 0.6 1.4 1.1 1.6 3.8 1.1 0.4 0.7 0.3 11.8 0.8 0.5 0.0 0.3 3.1 1.0 0.3 0.8 1.8 1.9 0.9 2.6 0.0 0.0 0.3 1.1 1.2 0.0 0.2 1.7 0.1 0.7 3.4 6.6 0.0 2.7 1.5 3.0 3.9 9.6 2.4 3.3 1.3 0.6 1.4 11.1 PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851325 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2792.8;Kupffer cells: 2427.0;Macrophages: 1916.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11615.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 5104.0;hTERT-RPE1: 6978.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB004647: AB_425625, HPA004426: AB_1079701" "unprognostic (4.43e-3)" "unprognostic (2.69e-1)" "unprognostic (1.64e-2)" "unprognostic (8.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-3)" "unprognostic (2.79e-1)" "unprognostic (3.31e-2)" "unprognostic (3.25e-2)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.06e-1)" 1068.6 1192.2 831.4 874.2 946.7 834.2 683.8 873.7 831.7 1073.9 1023.0 667.1 475.6 879.3 951.2 605.5 724.7 1115.6 1413.3 830.5 1081.8 860.4 906.4 1118.6 956.1 957.6 894.0 1106.9 544.7 1167.5 563.5 869.3 885.3 773.9 625.5 665.2 580.9 936.8 1409.5 544.4 487.7 1138.6 1025.9 1045.9 664.0 489.1 1048.8 672.3 875.9 987.5 560.4 941.2 578.3 1325.1 455.9 847.4 540.4 1121.0 5104.0 2910.1 1900.2 799.9 2368.3 620.8 735.9 795.4 1131.9 245.6 1608.1 1321.6 1038.9 964.1 207.5 659.1 434.8 481.4 381.8 288.9 352.3 459.6 1970.7 188.8 1596.0 1871.8 1479.1 625.7 1177.6 6978.9 1128.1 345.8 420.5 1158.1 777.0 294.9 843.8 290.1 249.5 575.4 404.0 172.9 301.3 696.7 730.3 764.4 584.4 515.8 751.1 2248.3 3122.2 700.4 454.4 431.1 1467.0 861.8 610.0 587.1 670.5 1289.0 1038.7 435.4 1375.5 374.4 650.0 863.2 10095.9 1127.5 424.2 11615.6 349.8 466.7 342.9 368.8 3481.1 425.5 370.1 350.6 2890.4 365.8 10148.2 1758.2 422.8 15009.0 831.4 946.7 873.7 831.7 830.5 1081.8 957.6 894.0 885.3 1025.9 1048.8 1325.1 263.2 253.2 339.0 136.8 173.9 228.3 253.4 487.0 108.1 193.8 254.6 158.7 664.1 253.1 318.9 476.3 127.2 891.6 260.2 434.8 70.5 1043.6 19.3 147.0 246.6 311.4 261.9 160.5 86.1 456.1 872.6 623.8 187.6 195.2 398.1 210.8 426.9 509.2 2792.8 333.1 93.7 242.2 343.8 2427.0 779.7 54.1 458.6 1916.9 663.5 105.9 1528.9 495.6 182.3 92.5 117.6 357.7 298.3 551.8 503.0 244.8 370.6 311.6 297.2 164.3 276.1 273.6 263.8 55.2 126.3 137.2 198.0 1073.2 138.9 624.1 228.3 223.9 PTGR2 "FLJ39091, ZADH1" ENSG00000140043 "Prostaglandin reductase 2" Q8N8N7 14 73851844-73886827 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 43.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 41.9" HPA001125 Approved Approved Vesicles NA NA 36000 "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA001125: AB_2666207" "unprognostic (3.82e-2)" "unprognostic (2.79e-2)" "unprognostic (6.05e-2)" "unprognostic (3.26e-1)" "unprognostic (2.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (2.80e-1)" "unprognostic (8.10e-3)" "unprognostic (6.99e-3)" "unprognostic (5.96e-1)" "prognostic favorable (4.55e-12)" "unprognostic (4.42e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (7.24e-2)" 6.9 12.2 10.4 2.8 11.5 0.9 9.1 11.1 12.1 4.8 11.6 7.2 12.1 4.6 17.2 5.0 12.0 5.2 27.1 9.9 11.7 18.9 19.1 5.6 3.1 11.8 11.9 7.4 5.3 10.6 7.6 2.4 12.1 9.1 5.7 10.7 6.7 5.4 32.8 6.9 8.9 2.6 11.3 3.4 6.2 6.2 10.6 3.0 12.6 32.1 2.6 4.2 4.1 13.9 8.9 11.9 9.6 4.7 7.6 16.3 7.6 3.0 4.1 3.6 5.6 6.8 21.2 0.9 6.8 3.0 8.4 8.8 8.7 6.5 6.6 6.7 4.1 6.2 5.5 3.0 3.8 2.3 2.2 7.7 15.1 5.5 4.4 7.8 1.8 6.1 8.3 1.8 8.2 12.7 6.2 5.9 10.7 11.9 11.6 7.6 3.7 1.5 19.7 8.6 12.7 11.0 7.7 8.1 9.8 9.1 41.9 3.7 2.7 5.3 10.0 3.9 6.6 10.2 4.7 2.8 8.3 5.5 7.2 6.7 1.1 0.9 0.6 0.4 0.6 1.0 1.1 0.5 1.3 1.0 1.8 1.5 0.8 1.3 1.2 1.5 1.1 1.0 10.4 11.5 11.1 12.1 9.9 11.7 11.8 11.9 12.1 11.3 10.6 13.9 4.5 19.2 13.0 10.7 2.9 6.8 12.8 16.7 6.2 8.9 8.4 5.5 43.2 8.6 12.9 18.4 14.6 6.3 2.0 8.6 25.4 11.7 2.4 21.5 5.8 5.2 4.8 4.2 8.0 8.7 2.5 6.1 5.1 7.3 3.8 9.3 3.3 14.3 7.4 33.7 10.3 10.0 10.2 5.5 3.1 2.0 7.2 4.3 8.8 5.6 4.0 22.3 6.2 7.1 20.4 8.7 11.1 6.8 2.9 7.2 24.8 18.4 31.6 20.8 6.6 9.9 6.1 42.1 18.8 3.5 6.7 4.0 2.9 17.3 11.7 7.7 PTPN9 MEG2 ENSG00000169410 "Protein tyrosine phosphatase non-receptor type 9" P43378 15 75463251-75579315 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 63.0;Excitatory neurons: 66.1;Inhibitory neurons: 63.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041922 Approved Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA041922: AB_10795269" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "unprognostic (2.42e-1)" "unprognostic (1.54e-2)" "unprognostic (6.80e-2)" "unprognostic (7.38e-2)" "unprognostic (5.95e-2)" "unprognostic (3.93e-1)" "unprognostic (3.14e-1)" "unprognostic (9.25e-3)" "unprognostic (6.35e-2)" "prognostic favorable (2.49e-6)" "unprognostic (2.26e-1)" "unprognostic (1.05e-1)" "unprognostic (2.71e-1)" "unprognostic (2.39e-1)" 15.9 12.0 14.8 13.0 16.3 10.8 15.1 11.9 18.8 16.6 11.7 18.0 17.9 16.5 13.3 9.9 16.2 12.1 11.0 16.9 18.4 18.2 14.7 15.8 14.5 18.6 14.4 14.0 10.2 17.9 9.7 19.9 15.1 16.6 19.7 8.9 13.0 21.2 6.4 11.0 20.0 18.0 13.6 13.4 13.5 7.2 17.0 16.1 32.8 13.1 15.0 18.1 13.8 14.5 20.3 24.1 36.7 24.6 26.8 29.3 12.0 29.8 46.2 36.9 33.4 14.5 30.0 32.6 23.3 51.1 29.5 30.0 79.9 34.3 37.0 40.5 19.8 18.4 16.2 15.7 40.2 28.2 27.1 38.4 35.2 29.6 45.9 37.7 31.4 21.3 12.4 11.5 42.1 13.5 20.0 26.3 33.6 18.2 12.1 38.9 18.2 9.1 46.6 32.5 14.4 29.9 42.4 23.3 46.3 34.9 12.1 47.8 36.5 35.2 11.3 23.3 32.2 16.9 18.9 30.0 20.5 41.9 35.3 3.2 2.2 2.3 3.4 3.0 2.8 1.7 2.4 3.0 3.0 1.3 1.0 1.8 0.3 3.9 2.9 2.0 1.6 1.7 14.8 16.3 11.9 18.8 16.9 18.4 18.6 14.4 15.1 13.6 17.0 14.5 12.7 6.4 13.4 63.0 9.2 3.3 8.2 6.6 5.7 12.1 8.0 7.1 3.7 10.0 8.1 11.0 8.4 20.0 7.3 25.0 15.6 10.8 3.0 7.9 19.4 10.0 7.2 13.7 66.1 9.9 4.2 20.6 10.7 11.4 15.2 23.6 17.5 12.6 18.8 3.3 63.2 11.5 6.1 18.9 18.1 4.7 12.5 16.5 7.2 46.9 24.2 5.6 19.6 48.7 19.6 18.2 12.6 27.4 9.7 12.1 24.9 14.0 8.1 17.1 13.1 11.7 20.8 10.6 9.4 6.6 3.3 10.1 13.4 11.6 13.2 13.1 PTPRN2 "IA-2beta, ICAAR, KIAA0387, phogrin" ENSG00000155093 "Protein tyrosine phosphatase receptor type N2" Q92932 7 157539056-158587823 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Protein phosphatase, Receptor" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;pancreas: 98.1" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 131.1;Excitatory neurons: 439.6;Inhibitory neurons: 433.4;Oligodendrocyte precursor cells: 138.2" "Cancer enhanced" "Detected in all" "prostate cancer: 40.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 23.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 23.6" "Cell line enhanced" "Detected in many" "AF22: 45.5;HDLM-2: 42.0;MOLT-4: 22.1;NB-4: 43.0;SCLC-21H: 23.8;SH-SY5Y: 25.4;U-87 MG: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006900, HPA007255, HPA026656" Enhanced Approved Vesicles NA NA 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA006900: AB_1079715, HPA007255: , HPA026656: AB_1855912" "unprognostic (2.42e-1)" "unprognostic (4.17e-2)" "unprognostic (7.82e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (9.37e-5)" "unprognostic (7.12e-3)" "unprognostic (1.04e-1)" "unprognostic (4.55e-2)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "prognostic favorable (8.68e-4)" "unprognostic (2.60e-2)" "unprognostic (1.48e-1)" "unprognostic (1.43e-3)" "unprognostic (6.16e-2)" 3.8 16.5 29.4 2.7 34.3 1.3 2.9 0.0 49.9 2.1 0.0 7.7 8.3 3.0 4.2 1.9 10.8 7.6 3.1 35.2 22.7 3.9 1.6 4.8 3.4 7.9 3.1 8.7 98.1 1.0 41.0 2.1 3.4 17.3 6.1 9.2 12.9 3.6 1.2 0.8 6.7 2.1 0.1 13.4 40.2 6.2 14.1 1.6 8.7 1.9 2.5 4.2 2.1 20.5 0.1 0.4 45.5 3.6 0.1 0.2 0.1 0.4 0.3 0.0 0.1 0.0 4.0 0.0 1.2 0.5 9.4 0.3 1.0 0.0 0.0 42.0 0.8 0.0 0.0 7.3 1.1 0.0 0.1 2.0 0.8 0.1 0.5 0.3 0.0 3.4 0.1 0.3 0.0 0.7 22.1 43.0 5.7 13.7 3.2 0.0 2.7 0.2 0.2 0.0 23.8 25.4 0.0 0.1 0.0 0.0 0.0 20.9 6.2 9.2 4.3 0.1 1.5 0.3 0.1 0.0 27.7 17.4 6.8 14.1 1.5 2.8 1.3 0.2 0.5 3.5 2.1 1.4 2.1 4.2 2.4 1.4 23.6 2.4 0.0 0.6 5.3 1.3 29.4 34.3 0.0 49.9 35.2 22.7 7.9 3.1 3.4 0.1 14.1 20.5 40.7 3.2 12.9 16.3 18.4 2.3 12.7 1.3 4.0 30.2 1.9 2.2 3.1 10.0 9.1 40.5 10.4 0.4 8.7 5.9 35.2 22.9 51.9 8.7 2.5 26.3 131.1 6.6 439.6 13.1 0.4 13.0 41.8 0.8 19.0 14.1 44.3 0.8 44.5 11.8 433.4 43.3 6.1 7.0 11.3 19.3 12.5 7.9 12.4 27.2 5.7 67.3 15.5 138.2 11.0 7.3 7.0 19.5 5.4 15.0 6.5 3.8 52.6 8.0 26.3 1.4 7.0 62.8 16.3 4.8 1.4 0.7 14.8 32.7 9.7 24.8 PUSL1 FLJ90811 ENSG00000169972 "Pseudouridine synthase like 1" Q8N0Z8 1 1308597-1311677 "Predicted intracellular proteins" "tRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 71.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032057, HPA039999" Uncertain Enhanced Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA032057: AB_10601251, HPA039999: AB_2676792" "unprognostic (2.04e-2)" "unprognostic (1.60e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (1.80e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (7.55e-2)" "unprognostic (4.35e-2)" "unprognostic (1.47e-1)" "unprognostic (2.44e-2)" "unprognostic (3.91e-2)" "prognostic unfavorable (1.62e-5)" "unprognostic (3.05e-1)" "unprognostic (1.48e-1)" "unprognostic (1.45e-1)" "unprognostic (2.44e-1)" 8.1 14.0 6.9 3.3 6.5 4.5 8.7 6.3 9.1 12.7 8.2 9.1 4.5 11.0 4.0 21.0 10.6 2.6 9.8 6.7 6.1 9.4 14.4 8.3 3.9 7.9 6.2 9.1 14.9 3.3 14.9 3.2 6.7 11.7 2.0 2.0 13.7 4.3 7.9 18.1 8.9 2.6 6.2 10.2 10.8 10.9 6.2 4.2 7.5 2.3 3.5 10.4 12.3 7.6 21.9 9.8 9.7 16.6 4.6 7.4 13.1 19.4 10.7 18.8 12.6 33.9 14.1 13.3 15.4 9.6 8.0 17.8 10.8 17.8 3.3 15.1 71.0 18.5 17.7 20.5 17.4 22.2 17.1 7.2 9.2 10.4 7.9 5.1 8.6 18.3 24.1 6.0 8.8 18.2 21.1 28.9 13.2 18.4 42.6 19.2 7.3 32.0 14.8 8.3 44.3 16.2 15.3 45.1 16.1 4.5 12.7 14.6 10.2 12.1 12.5 19.9 18.8 23.4 8.1 57.4 15.0 20.0 7.4 3.7 12.5 6.2 10.2 17.5 10.3 8.5 11.1 8.6 11.7 9.2 7.2 7.3 4.9 9.0 15.9 7.3 14.4 8.4 6.9 6.5 6.3 9.1 6.7 6.1 7.9 6.2 6.7 6.2 6.2 7.6 5.7 0.0 5.3 1.0 8.9 22.0 12.0 19.9 11.4 8.1 16.3 14.0 2.5 8.6 13.5 7.3 6.2 27.0 8.4 15.0 11.7 20.9 11.5 7.7 9.3 6.6 5.3 3.4 2.4 23.1 41.9 9.3 12.2 5.2 7.0 6.3 4.6 10.5 20.9 3.3 2.4 12.5 16.2 8.8 17.4 18.2 8.7 7.4 7.2 0.0 7.7 5.9 10.3 1.5 2.2 26.1 9.9 11.3 14.2 16.8 13.4 18.9 12.0 7.9 0.0 5.2 9.3 17.1 18.5 13.4 19.2 34.5 9.7 18.3 13.2 25.6 PXT1 STEPP ENSG00000179165 "Peroxisomal testis enriched protein 1" Q8NFP0 6 36390551-36442854 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.3" "Group enriched" "Detected in some" 4 "Spermatocytes: 10.6;Spermatogonia: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "HDLM-2: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA044042 Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA044042: AB_10963537" "unprognostic (1.85e-2)" "unprognostic (1.12e-3)" "unprognostic (9.92e-2)" "unprognostic (5.49e-2)" "unprognostic (4.43e-1)" "unprognostic (9.38e-2)" "unprognostic (2.28e-2)" "unprognostic (2.92e-3)" "unprognostic (4.64e-2)" "unprognostic (1.92e-1)" "unprognostic (5.86e-2)" "unprognostic (3.15e-1)" "unprognostic (4.94e-5)" "unprognostic (2.98e-1)" "unprognostic (2.16e-1)" "unprognostic (7.21e-3)" "unprognostic (2.61e-3)" 0.1 0.0 0.2 0.3 0.1 0.2 0.1 0.2 0.3 0.0 0.1 0.0 0.3 0.1 0.2 0.0 0.1 0.2 0.1 0.2 0.1 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 2.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.3 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 1.0 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.9 0.2 0.4 0.1 0.0 0.0 0.7 0.2 0.1 0.2 1.1 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.7 0.2 0.0 1.8 0.0 0.7 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.2 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.2 10.6 4.9 0.0 0.0 0.3 0.5 0.1 0.2 0.2 QPRT QPRTase ENSG00000103485 "Quinolinate phosphoribosyltransferase" Q15274 16 29663279-29698699 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 119.4;liver: 183.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 404.7;Extravillous trophoblasts: 315.1;Hepatocytes: 367.4;Proximal tubular cells: 598.8;Syncytiotrophoblasts: 215.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 4.2;intermediate monocyte: 5.3;myeloid DC: 5.8;non-classical monocyte: 9.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 8 "dendritic cells: 5.8;monocytes: 9.0" "Cell line enhanced" "Detected in many" "EFO-21: 597.1;Hep G2: 258.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011887, HPA076010" Enhanced Approved Vesicles "Intracellular and membrane" NA NA 780000 "Cluster 7: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA011887: AB_2668555, HPA076010: " "prognostic unfavorable (5.10e-5)" "unprognostic (2.00e-1)" "unprognostic (9.48e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (9.31e-4)" "unprognostic (1.44e-2)" "unprognostic (8.75e-2)" "unprognostic (1.22e-1)" "unprognostic (8.16e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-1)" "unprognostic (6.81e-2)" "unprognostic (3.37e-2)" "unprognostic (1.33e-2)" "unprognostic (2.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.58e-2)" 8.4 89.4 20.6 4.3 20.2 4.8 6.7 25.8 19.8 50.6 19.4 19.2 61.6 26.1 95.2 4.0 43.6 10.2 26.8 18.5 22.2 119.4 183.5 9.2 6.8 28.6 26.6 31.0 34.5 16.2 5.8 27.3 32.4 7.0 15.2 7.5 13.4 26.1 5.1 5.1 30.3 13.7 23.6 17.2 7.1 4.1 22.8 8.2 6.5 1.2 5.2 10.5 11.5 23.3 0.6 1.4 51.8 56.4 8.8 21.6 167.8 6.0 5.2 8.6 11.0 145.9 91.9 2.3 597.1 10.8 10.0 1.0 18.5 0.6 4.5 0.8 16.7 27.1 2.2 258.0 52.5 4.1 10.4 69.8 1.4 4.8 0.2 12.8 0.2 28.2 75.1 2.9 0.4 154.6 17.6 100.3 162.1 1.9 0.2 89.3 16.3 58.5 47.9 4.2 48.6 103.5 0.0 142.1 118.8 85.1 106.5 112.8 0.6 2.5 24.9 0.9 0.5 1.8 4.9 18.8 4.4 10.4 8.1 0.0 4.2 0.3 0.8 5.3 0.9 0.1 0.6 0.7 5.8 0.0 0.1 0.4 0.8 0.4 9.0 3.1 0.9 1.9 20.6 20.2 25.8 19.8 18.5 22.2 28.6 26.6 32.4 23.6 22.8 23.3 3.1 9.6 24.8 5.2 10.1 3.6 11.7 0.5 1.8 3.3 5.0 2.0 43.2 8.6 3.0 64.4 0.0 404.7 5.8 84.5 50.9 1.2 0.0 93.8 49.5 5.5 28.3 10.5 1.3 55.2 315.1 35.8 0.5 81.0 5.1 6.7 9.7 367.4 147.5 6.7 5.6 47.3 0.0 21.2 18.3 0.5 29.2 19.8 42.7 12.2 4.4 20.8 3.1 11.1 0.5 11.5 78.5 27.1 8.7 4.2 161.0 598.8 1.5 5.0 6.6 3.3 16.2 0.5 3.0 0.2 2.0 215.6 5.7 36.5 104.7 8.3 RAB11FIP1 "FLJ22524, FLJ22622, Rab11-FIP1, RCP" ENSG00000156675 "RAB11 family interacting protein 1" Q6WKZ4 8 37858618-37899497 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 798.0;Endometrial ciliated cells: 622.9;Glandular and luminal cells: 969.7;Urothelial cells: 613.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 101.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 101.9" "Cell line enhanced" "Detected in many" "K-562: 73.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB017037, HPA023904, HPA024010, HPA025960" Enhanced Enhanced Vesicles No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Vesicles "CAB017037: , HPA023904: AB_1855990, HPA024010: AB_1855991, HPA025960: AB_1855992" "unprognostic (1.62e-2)" "unprognostic (3.47e-2)" "unprognostic (3.22e-3)" "unprognostic (2.87e-1)" "unprognostic (1.06e-1)" "prognostic favorable (6.61e-4)" "unprognostic (4.32e-1)" "unprognostic (4.50e-3)" "unprognostic (1.58e-1)" "unprognostic (4.72e-2)" "unprognostic (2.82e-3)" "unprognostic (2.73e-2)" "prognostic favorable (1.14e-6)" "unprognostic (4.94e-2)" "unprognostic (8.41e-2)" "unprognostic (9.99e-2)" "unprognostic (1.50e-1)" 7.5 5.7 3.8 17.7 2.7 58.5 21.8 3.8 3.8 14.5 39.3 40.7 41.3 5.9 14.8 47.1 16.9 21.7 12.0 4.4 4.3 13.7 7.2 74.0 17.2 3.4 2.7 4.6 42.5 12.0 8.6 25.8 2.1 8.7 47.0 6.1 23.8 13.5 4.6 18.9 53.5 7.1 2.3 12.0 45.5 6.4 4.0 15.4 13.0 2.7 31.1 23.6 14.9 2.2 41.8 18.1 1.9 8.0 0.4 0.1 54.1 4.2 6.6 7.5 9.6 40.6 23.2 17.0 12.7 5.1 0.4 31.6 14.5 9.4 11.3 44.2 13.5 3.3 9.0 11.9 20.9 7.3 36.3 4.8 12.2 2.8 7.9 11.1 0.1 22.2 73.1 8.2 3.8 9.9 12.4 10.7 12.0 40.9 5.3 3.9 9.7 13.2 39.4 42.2 7.4 8.5 10.6 52.3 13.0 36.8 35.2 14.0 0.6 0.2 23.1 0.6 0.7 16.5 20.7 4.5 0.3 9.8 5.7 24.0 20.5 38.1 4.4 9.4 9.9 6.0 3.2 3.1 18.3 3.8 2.0 2.2 101.9 10.9 20.2 11.0 7.7 10.7 3.8 2.7 3.8 3.8 4.4 4.3 3.4 2.7 2.1 2.3 4.0 2.2 7.6 798.0 112.9 1.0 128.5 15.9 113.5 49.5 24.5 5.4 113.6 58.5 15.8 84.4 228.0 64.4 16.7 44.9 123.6 385.5 15.6 170.2 0.9 622.9 71.4 25.3 243.7 3.8 7.9 248.9 8.1 28.7 272.7 969.7 30.4 2.8 32.2 15.3 32.1 6.7 8.6 312.3 95.6 59.1 174.7 1.8 1.8 121.1 16.0 2.8 95.2 18.6 120.5 0.0 1.0 364.6 299.1 1.5 48.2 192.7 331.9 16.5 348.8 21.0 6.6 9.0 23.3 2.4 5.2 124.2 30.5 96.0 83.8 2.8 256.6 613.9 RAB12 ENSG00000206418 "RAB12, member RAS oncogene family" Q6IQ22 18 8609437-8639382 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 193.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 96.4;Inhibitory neurons: 46.3;Microglial cells: 45.9;Oligodendrocytes: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040727 Approved Approved Vesicles NA NA "Cluster 42: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA040727: AB_10794858" "unprognostic (7.92e-2)" "unprognostic (4.11e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-2)" "unprognostic (1.53e-2)" "unprognostic (1.47e-2)" "unprognostic (1.25e-2)" "unprognostic (2.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.29e-3)" "unprognostic (2.67e-1)" "unprognostic (5.72e-2)" "unprognostic (2.02e-1)" "unprognostic (1.63e-1)" "unprognostic (1.46e-1)" "unprognostic (1.61e-1)" "unprognostic (9.11e-2)" 36.8 26.2 27.0 17.8 29.8 13.6 27.9 31.6 33.9 28.3 21.6 34.9 11.8 29.7 19.6 28.8 26.7 18.5 85.4 30.0 31.3 31.4 36.5 30.3 20.9 25.3 27.3 31.0 13.4 21.7 21.3 30.0 25.8 22.7 16.9 22.6 18.0 29.7 193.8 31.5 20.2 34.3 28.3 28.0 19.2 12.0 32.7 15.2 19.8 106.6 20.8 29.0 25.3 27.2 33.1 19.4 22.1 23.2 64.3 54.2 12.2 44.0 60.2 49.1 57.4 26.3 29.7 11.3 41.7 53.1 36.8 20.6 25.7 47.1 59.3 4.5 20.8 9.7 20.7 27.7 59.5 12.8 9.8 53.9 65.2 36.3 45.9 50.6 60.2 10.0 15.0 15.8 48.2 35.9 14.8 12.9 14.3 113.8 18.0 10.2 53.6 10.9 48.5 43.8 36.5 25.8 33.6 45.1 57.6 31.0 13.2 19.5 50.6 56.6 33.0 57.2 67.7 10.6 6.6 9.8 42.4 11.8 37.0 4.5 0.9 1.0 0.8 1.5 1.1 1.3 0.9 0.9 0.7 1.1 1.1 1.1 1.6 1.5 2.4 1.7 1.0 0.5 27.0 29.8 31.6 33.9 30.0 31.3 25.3 27.3 25.8 28.3 32.7 27.2 34.1 12.8 19.3 31.6 3.8 6.5 1.7 1.9 2.8 15.1 11.6 12.2 96.4 1.5 8.3 3.7 6.2 1.8 7.1 1.6 3.9 2.3 0.0 8.1 14.1 16.1 5.4 3.2 41.6 1.3 1.4 14.5 4.6 7.6 6.3 9.4 16.4 16.0 1.7 11.8 46.3 2.5 2.0 16.6 12.3 0.4 3.4 9.3 3.6 45.9 4.5 14.1 2.1 23.6 43.3 3.2 1.7 4.5 2.4 6.3 2.2 5.9 7.0 7.7 0.0 13.2 13.6 1.0 1.5 4.5 8.4 1.1 4.5 12.3 3.1 4.5 RAB14 "FBP, RAB-14" ENSG00000119396 "RAB14, member RAS oncogene family" P61106 9 121178133-121223014 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026419, CAB037066" Approved Supported Vesicles NA NA 2700000 "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB037066: AB_1841128, HPA026419: AB_1855996" "unprognostic (1.30e-3)" "unprognostic (3.12e-2)" "unprognostic (9.01e-2)" "unprognostic (7.18e-2)" "unprognostic (6.53e-2)" "unprognostic (3.00e-1)" "unprognostic (1.39e-1)" "unprognostic (1.18e-1)" "unprognostic (2.52e-1)" "unprognostic (6.90e-2)" "unprognostic (3.05e-2)" "unprognostic (9.71e-3)" "prognostic favorable (1.79e-8)" "unprognostic (1.38e-1)" "unprognostic (3.17e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" 39.0 38.7 37.5 35.6 39.7 66.5 42.1 40.3 47.7 37.8 32.6 42.8 39.9 35.6 34.2 63.2 34.0 30.7 32.4 38.4 40.9 50.0 82.8 49.2 41.1 39.6 39.9 35.9 27.6 45.8 28.9 43.1 40.5 38.8 42.4 45.5 34.6 38.1 39.4 56.4 38.9 33.4 40.8 38.3 44.3 33.8 40.2 35.2 43.8 38.9 49.5 43.9 40.8 46.8 53.8 53.7 66.9 56.3 76.2 82.5 52.6 74.8 59.6 56.6 44.7 42.6 57.0 51.2 42.5 72.0 49.2 100.1 48.1 55.8 63.6 44.4 31.7 55.7 69.0 43.9 52.6 60.1 63.8 53.0 98.5 58.2 63.4 62.5 81.2 47.1 42.8 45.6 85.6 50.8 58.5 48.1 39.7 104.8 59.9 45.8 72.3 60.4 62.3 76.0 58.9 34.4 89.0 78.0 53.8 47.1 82.1 46.8 76.0 60.1 43.9 75.3 53.0 40.8 82.6 52.3 56.6 51.9 80.7 34.4 29.4 33.5 22.4 41.5 22.4 24.6 20.9 24.7 31.4 23.4 24.6 25.0 31.8 26.5 43.7 19.0 29.3 24.0 37.5 39.7 40.3 47.7 38.4 40.9 39.6 39.9 40.5 40.8 40.2 46.8 102.6 160.3 103.9 23.5 64.4 157.9 78.2 84.8 97.3 93.8 70.7 58.8 39.2 62.9 96.2 62.5 37.5 85.2 79.6 95.1 86.1 81.3 41.9 80.7 89.8 84.5 60.3 44.4 42.5 64.4 83.0 68.7 64.7 94.4 77.2 58.1 61.1 113.6 91.0 94.2 38.0 59.8 95.6 89.9 105.4 36.2 51.9 80.7 110.3 44.0 84.8 100.5 49.4 38.2 59.0 80.7 52.9 56.4 50.2 81.0 63.2 103.3 86.8 62.0 59.2 64.0 105.6 112.9 113.6 120.0 202.4 116.2 74.3 82.5 64.0 106.0 RAB30 ENSG00000137502 "RAB30, member RAS oncogene family" Q15771 11 82973133-83071923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.7" "Cell type enhanced" "Detected in many" "Astrocytes: 87.8;Oligodendrocytes: 243.1;Plasma cells: 260.9" "Cancer enhanced" "Detected in all" "breast cancer: 6.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 54.4;naive B-cell: 55.0" "Lineage enriched" "Detected in many" 5 "B-cells: 55.0" "Cell line enhanced" "Detected in many" "Daudi: 55.7;HDLM-2: 57.6;U-698: 164.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054514, HPA060565" Approved Enhanced Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA054514: AB_2682512, HPA060565: AB_2684320" "unprognostic (3.21e-1)" "unprognostic (1.03e-1)" "unprognostic (1.82e-1)" "unprognostic (5.18e-2)" "unprognostic (7.21e-2)" "unprognostic (8.06e-2)" "unprognostic (2.91e-2)" "unprognostic (3.14e-2)" "unprognostic (4.36e-1)" "unprognostic (1.71e-2)" "unprognostic (1.53e-1)" "unprognostic (3.75e-2)" "unprognostic (1.64e-2)" "unprognostic (2.37e-1)" "unprognostic (2.42e-1)" "unprognostic (3.93e-2)" "unprognostic (1.85e-1)" 11.2 11.0 12.3 13.9 28.0 14.5 12.4 20.5 12.9 8.3 0.0 13.1 17.8 8.4 5.8 6.9 5.5 5.7 9.3 10.5 24.2 3.7 7.7 6.5 19.8 28.0 19.1 14.0 4.3 2.9 4.4 8.5 28.6 7.2 13.8 11.2 6.1 5.2 12.9 7.4 21.3 10.2 20.3 10.1 11.6 4.0 21.8 10.4 5.8 11.8 28.4 8.9 4.4 39.7 4.1 5.6 5.8 2.9 11.1 16.7 6.8 9.8 9.1 19.0 7.9 8.7 1.8 55.7 10.0 14.9 4.9 4.8 8.3 6.4 11.3 57.6 1.6 12.6 16.4 5.1 2.6 2.0 2.5 9.5 4.4 8.5 6.5 7.2 14.0 5.0 1.9 15.0 9.8 7.9 2.1 0.6 7.7 5.5 10.0 4.8 15.2 23.7 9.5 3.4 6.7 4.6 22.6 5.3 2.7 8.6 12.4 0.2 17.9 8.1 19.1 8.0 2.7 24.0 14.3 164.6 3.1 1.4 5.7 1.4 0.7 1.0 4.9 0.3 3.6 54.4 4.8 4.8 2.0 55.0 11.2 10.0 0.9 2.3 0.8 5.8 9.5 6.2 12.3 28.0 20.5 12.9 10.5 24.2 28.0 19.1 28.6 20.3 21.8 39.7 15.2 9.6 3.3 87.8 80.5 24.9 10.7 9.9 73.4 8.3 11.7 13.0 14.5 0.0 2.7 3.7 16.7 7.0 6.8 5.4 1.9 2.4 0.7 3.3 6.1 10.5 10.1 3.2 60.7 4.0 30.8 23.5 5.1 4.2 0.0 0.9 18.2 6.4 1.9 11.8 78.2 1.5 8.2 1.6 15.2 1.3 14.3 6.4 42.7 67.5 24.8 13.9 3.1 80.4 243.1 4.3 3.5 18.0 260.9 8.9 9.3 4.6 2.3 10.5 6.6 20.3 13.5 0.7 2.2 11.0 11.5 2.9 12.9 24.0 1.8 2.0 RAB33A RabS10 ENSG00000134594 "RAB33A, member RAS oncogene family" Q14088 X 130171962-130184870 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.5;choroid plexus: 16.4;heart muscle: 15.2" "Cell type enhanced" "Detected in many" "granulocytes: 22.9;Melanocytes: 12.4;NK-cells: 22.6;Oligodendrocytes: 23.5;T-cells: 12.9" "Group enriched" "Detected in many" 6 "glioma: 10.7;melanoma: 2.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 111.4;Karpas-707: 126.8;U-266/70: 88.5;U-937: 55.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059737 Uncertain Uncertain Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA059737: AB_2684115" "unprognostic (5.40e-2)" "unprognostic (6.64e-3)" "unprognostic (3.48e-2)" "unprognostic (8.47e-3)" "unprognostic (4.88e-2)" "unprognostic (1.17e-2)" "unprognostic (2.34e-1)" "unprognostic (1.76e-2)" "unprognostic (3.12e-2)" "unprognostic (4.16e-2)" "unprognostic (3.03e-2)" "unprognostic (8.28e-2)" "unprognostic (7.00e-6)" "unprognostic (2.51e-1)" "unprognostic (6.35e-2)" "unprognostic (3.45e-2)" "unprognostic (1.61e-1)" 2.3 1.3 23.6 4.0 28.2 6.3 1.3 27.9 31.6 2.3 16.4 0.9 0.7 1.7 0.5 0.5 1.6 2.6 15.2 24.4 24.4 1.7 0.9 1.7 11.6 29.0 24.7 1.4 0.2 2.0 2.2 1.4 29.7 0.4 1.0 7.6 0.5 0.1 0.1 1.1 2.2 0.7 27.8 2.5 1.4 0.6 25.7 4.8 0.6 0.2 12.3 1.7 0.8 41.5 0.3 0.2 7.5 0.0 3.2 1.0 0.1 1.0 2.2 1.9 3.2 0.1 0.8 5.8 0.1 0.6 0.5 0.2 9.4 0.2 2.0 30.2 0.1 35.0 0.1 0.0 31.3 28.4 111.4 1.0 0.2 0.6 1.3 1.0 0.8 34.7 0.1 126.8 0.3 0.3 13.1 9.7 1.1 0.1 1.3 0.0 0.0 1.6 0.2 0.0 24.3 19.4 0.2 0.3 0.5 0.4 0.0 15.2 0.2 0.1 0.1 0.4 0.2 88.5 29.7 0.0 3.9 55.1 0.0 39.9 1.3 87.4 32.0 0.8 20.0 20.2 29.0 32.5 10.0 8.8 27.8 40.0 4.1 19.5 5.4 1.0 72.8 18.1 23.6 28.2 27.9 31.6 24.4 24.4 29.0 24.7 29.7 27.8 25.7 41.5 1.7 0.0 1.1 1.6 3.2 1.9 0.6 0.5 1.2 10.9 0.3 1.0 8.4 2.8 0.2 0.0 2.1 0.9 8.9 0.0 0.0 0.0 1.2 0.4 0.8 2.0 0.0 6.6 4.0 0.2 1.3 4.5 0.0 0.8 22.9 2.9 2.5 0.1 1.9 5.0 3.2 0.4 2.0 0.3 12.0 1.2 1.8 6.3 12.4 1.9 2.5 1.6 22.6 4.5 23.5 0.8 0.0 0.4 3.3 0.4 0.0 0.2 0.3 9.3 0.0 0.0 2.2 0.1 1.2 0.2 1.1 1.4 12.9 0.2 0.3 0.6 RAB36 ENSG00000100228 "RAB36, member RAS oncogene family" O95755 22 23145326-23164350 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 32.8" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 41.2;Late spermatids: 24.5;Respiratory ciliated cells: 69.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 11.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 11.0" "Cell line enhanced" "Detected in many" "RPMI-8226: 25.5;U-266/84: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059631 Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 25: RPMI-8226 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA059631: " "unprognostic (2.74e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-2)" "unprognostic (1.23e-2)" "unprognostic (1.15e-2)" "unprognostic (6.60e-2)" "unprognostic (1.22e-1)" "unprognostic (3.46e-1)" "unprognostic (2.49e-2)" "unprognostic (7.94e-2)" "unprognostic (2.02e-3)" "unprognostic (5.56e-3)" "prognostic favorable (4.55e-4)" "unprognostic (7.08e-2)" "unprognostic (7.18e-2)" "unprognostic (1.64e-1)" "unprognostic (3.08e-1)" 2.0 5.1 8.8 1.3 8.7 0.7 2.6 3.8 8.4 5.1 21.7 3.2 0.7 4.8 4.4 2.1 32.8 5.3 1.4 9.9 9.1 9.1 0.4 4.8 1.1 9.4 11.2 6.2 3.4 5.6 17.1 2.9 6.9 3.9 1.1 2.0 3.3 6.6 0.6 1.8 1.2 3.8 7.9 1.6 2.1 6.7 10.4 0.3 17.6 0.4 1.3 2.5 2.1 5.1 8.1 9.4 7.1 10.7 1.6 3.4 2.8 4.5 9.1 9.8 3.7 0.6 0.0 0.0 4.8 6.0 5.4 10.0 0.3 5.2 3.1 0.0 4.3 0.1 0.4 0.9 4.1 0.0 1.2 4.3 1.9 9.1 1.8 6.4 1.4 0.0 0.4 8.1 0.4 6.4 0.1 0.1 0.9 5.3 2.5 0.0 0.0 25.5 12.7 1.5 17.3 7.5 0.4 3.9 2.2 0.5 0.0 0.9 0.8 1.3 2.9 3.4 6.5 17.3 26.2 0.1 8.8 0.0 5.8 0.3 0.6 0.0 0.5 0.2 0.3 0.8 0.1 0.2 0.2 0.2 0.3 0.3 11.0 1.6 0.3 0.0 0.0 0.3 8.8 8.7 3.8 8.4 9.9 9.1 9.4 11.2 6.9 7.9 10.4 5.1 0.6 0.0 3.2 3.6 1.4 0.5 0.8 4.2 0.0 0.7 1.8 2.8 0.8 4.3 7.0 1.8 6.2 6.0 0.3 0.0 5.9 3.5 10.6 41.2 2.9 0.7 6.7 0.0 2.9 0.2 0.4 2.0 1.5 2.6 1.3 2.4 1.1 0.1 0.4 1.7 1.7 0.7 6.1 0.8 0.3 24.5 3.4 0.3 1.8 1.0 0.5 3.6 1.0 1.5 1.0 0.2 0.2 3.0 0.3 0.4 0.0 9.6 69.6 0.7 0.0 1.0 2.0 3.6 1.6 0.5 0.1 2.9 0.4 4.5 0.3 0.4 RAB3D "D2-2, GOV, RAB16, RAD3D" ENSG00000105514 "RAB3D, member RAS oncogene family" O95716 19 11322068-11346270 "Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 68.5;skin 1: 53.1" "Cell type enhanced" "Detected in many" "monocytes: 53.1;Squamous epithelial cells: 47.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 169.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 47.3;Karpas-707: 45.6;MCF7: 54.6;SK-BR-3: 68.8" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 73.1" "CAB018067, HPA063283" Approved Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB018067: AB_606903, HPA063283: AB_2684976" "unprognostic (4.71e-3)" "unprognostic (3.00e-1)" "unprognostic (1.79e-1)" "unprognostic (3.99e-3)" "prognostic unfavorable (3.70e-4)" "unprognostic (4.17e-3)" "unprognostic (7.27e-3)" "unprognostic (1.55e-1)" "unprognostic (2.80e-1)" "unprognostic (8.76e-2)" "unprognostic (9.92e-2)" "unprognostic (4.45e-2)" "unprognostic (7.60e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-1)" "unprognostic (9.15e-2)" "unprognostic (1.34e-1)" 5.5 3.4 11.5 5.1 9.9 17.6 12.2 8.5 13.0 15.0 6.3 8.1 8.1 7.3 6.1 34.1 8.7 3.9 3.6 16.1 13.0 5.8 1.8 8.7 2.4 20.7 10.8 4.2 68.5 4.4 4.7 7.2 23.4 17.1 8.6 1.7 30.1 8.1 2.5 53.1 6.1 8.8 12.2 8.8 19.5 1.4 15.2 4.7 6.2 4.2 9.1 7.0 15.2 14.1 1.5 14.2 4.4 17.7 7.1 12.3 0.9 1.3 3.8 2.5 2.5 5.1 0.5 0.6 16.0 8.6 4.7 19.1 7.5 11.9 2.2 7.8 1.1 5.8 6.7 5.8 4.4 3.1 13.2 5.3 47.3 2.1 5.1 6.5 20.5 4.3 2.1 45.6 0.8 54.6 2.2 6.9 3.7 28.7 14.4 2.1 0.0 16.1 22.0 14.2 4.9 9.5 4.3 68.8 9.3 6.0 41.1 35.1 7.9 2.4 0.8 11.4 0.2 15.5 21.3 3.2 8.4 19.0 2.6 123.5 84.1 95.6 3.2 51.4 5.6 2.2 3.2 2.6 35.5 2.2 2.2 2.7 169.1 1.6 41.3 0.9 5.7 26.3 11.5 9.9 8.5 13.0 16.1 13.0 20.7 10.8 23.4 12.2 15.2 14.1 10.0 6.4 17.2 4.6 4.0 15.7 4.5 13.7 12.5 0.7 23.6 14.1 4.3 10.0 19.1 14.7 0.0 8.0 4.4 5.7 11.7 4.8 0.5 5.4 6.6 9.7 18.6 5.9 9.2 25.6 6.6 5.4 23.0 14.0 12.7 4.1 17.9 1.5 9.4 0.0 5.4 29.3 4.1 40.0 2.4 0.2 4.4 16.0 8.8 5.6 53.1 5.3 2.1 1.0 1.3 12.7 5.8 4.9 8.5 11.7 1.4 3.6 1.8 0.4 6.6 3.3 8.5 0.1 2.5 47.8 37.8 10.4 3.9 3.8 15.4 5.9 RAB40A "Rar-2, RAR2A" ENSG00000172476 "RAB40A, member RAS oncogene family" Q8WXH6 X 103499130-103519489 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 8.0" "Group enriched" "Detected in some" 5 "Astrocytes: 4.9;Excitatory neurons: 7.4;Inhibitory neurons: 7.3;Microglial cells: 5.6;Oligodendrocyte precursor cells: 6.6;Oligodendrocytes: 3.3;Peritubular cells: 6.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.3;NTERA-2: 3.7" HPA076172 Uncertain Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA076172: " "unprognostic (3.49e-1)" "unprognostic (6.01e-2)" "unprognostic (4.33e-2)" "unprognostic (4.49e-3)" "unprognostic (8.73e-2)" "unprognostic (1.08e-1)" "unprognostic (8.21e-2)" "unprognostic (1.72e-1)" "unprognostic (1.24e-1)" "unprognostic (4.05e-1)" "unprognostic (3.82e-2)" "unprognostic (4.43e-1)" "unprognostic (7.36e-4)" "unprognostic (7.85e-3)" "unprognostic (9.39e-5)" "unprognostic (1.43e-1)" "unprognostic (1.11e-3)" 2.0 1.2 1.0 0.2 3.1 0.1 0.9 0.7 1.4 3.0 6.4 0.6 0.4 4.5 8.0 7.1 2.3 0.5 0.7 1.6 1.2 1.3 0.3 1.3 0.2 0.8 0.3 4.6 0.5 0.2 2.4 0.6 0.3 3.5 0.3 1.3 0.4 2.1 0.2 0.5 0.5 0.9 0.0 0.6 0.8 3.8 1.1 0.1 0.7 0.2 0.1 2.3 1.5 1.0 0.2 0.9 3.3 0.1 0.7 0.9 1.6 1.0 0.2 0.1 0.3 0.7 0.5 0.8 1.2 0.2 1.0 0.0 0.2 0.0 0.1 0.0 2.0 0.2 1.8 0.2 0.3 0.0 0.1 0.7 0.1 0.3 0.2 1.2 0.2 0.3 1.2 0.5 0.3 0.2 0.2 0.1 3.7 0.0 0.5 0.0 0.2 0.0 0.0 0.3 1.4 1.7 0.3 0.0 0.7 0.9 0.0 0.1 1.7 1.3 0.8 2.1 0.9 0.6 0.4 0.6 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.1 0.7 1.4 1.6 1.2 0.8 0.3 0.3 0.0 1.1 1.0 0.3 0.0 0.0 4.9 0.0 0.0 0.7 0.1 0.0 0.2 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.6 0.1 0.0 0.0 7.4 0.0 0.2 0.2 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.0 7.3 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.0 5.6 0.0 0.2 0.0 6.6 3.3 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.0 RAB40AL "RAR2, RLGP" ENSG00000102128 "RAB40A like" P0C0E4 X 102937272-102938300 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.8;Cone photoreceptor cells: 2.1;Enteroendocrine cells: 3.0;Hepatic stellate cells: 2.2;Horizontal cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA076172 Uncertain Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA076172: " "unprognostic (1.99e-1)" "unprognostic (3.05e-1)" "unprognostic (1.31e-1)" "unprognostic (1.11e-2)" "unprognostic (1.24e-1)" "unprognostic (1.04e-1)" "unprognostic (2.91e-1)" "unprognostic (1.39e-1)" "unprognostic (3.49e-1)" "unprognostic (1.83e-1)" "unprognostic (1.15e-1)" "unprognostic (2.18e-2)" "unprognostic (5.90e-10)" "unprognostic (4.74e-1)" "unprognostic (1.32e-1)" "unprognostic (5.02e-3)" "unprognostic (2.64e-2)" 0.1 0.1 0.5 0.0 0.4 0.0 0.1 0.2 1.1 0.1 0.3 0.1 0.1 0.2 0.3 0.1 0.1 0.0 0.1 0.5 0.4 0.1 0.2 0.1 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.0 0.3 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.8 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.4 0.2 1.1 0.5 0.4 0.3 0.0 0.3 0.0 0.1 0.8 0.2 0.0 0.0 0.0 0.4 0.1 0.1 0.0 1.2 1.8 0.1 0.1 0.1 0.0 0.0 0.0 2.1 0.9 1.3 0.6 0.0 0.0 0.1 0.1 0.2 0.4 3.0 0.4 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.1 2.2 0.9 0.4 1.7 0.0 0.2 0.0 0.8 0.0 1.0 1.5 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.3 1.5 0.0 0.5 0.4 0.0 0.0 0.6 0.0 1.2 0.1 0.3 0.3 0.1 0.0 0.7 0.0 0.1 0.6 0.3 RAB40B "RAR, SEC4L" ENSG00000141542 "RAB40B, member RAS oncogene family" Q12829 17 82654973-82698698 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 75.5" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 134.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 33.2;OE19: 40.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076172 Approved Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles "HPA076172: " "unprognostic (2.21e-2)" "unprognostic (7.50e-2)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "unprognostic (1.14e-1)" "unprognostic (6.03e-2)" "unprognostic (2.34e-2)" "prognostic favorable (9.77e-4)" "unprognostic (1.74e-1)" "unprognostic (3.28e-2)" "unprognostic (1.36e-1)" "unprognostic (3.14e-2)" "prognostic favorable (2.95e-6)" "unprognostic (1.81e-2)" "unprognostic (1.38e-1)" "unprognostic (2.13e-2)" "unprognostic (9.83e-3)" 8.5 8.6 53.6 2.0 63.1 0.8 9.8 52.1 60.5 8.7 25.7 13.2 7.4 8.7 14.7 9.2 7.6 5.3 19.0 52.1 44.4 19.4 14.7 5.2 2.0 58.0 55.1 12.4 6.7 5.0 15.9 3.1 52.7 9.4 7.8 3.4 9.7 5.4 42.5 13.0 6.2 4.1 51.6 4.2 17.5 5.1 53.2 2.1 6.2 19.7 2.3 11.3 9.3 75.5 7.3 11.7 3.5 10.5 8.6 10.7 5.2 7.9 2.2 4.9 1.6 3.8 1.9 1.0 15.4 8.0 3.1 13.1 6.8 6.4 4.3 0.6 33.2 2.8 12.2 10.9 4.3 0.8 3.1 9.2 10.2 2.8 2.2 4.7 4.6 7.0 8.5 1.0 6.7 9.7 2.8 6.4 0.7 40.6 15.3 6.8 9.1 6.3 17.2 13.3 19.1 12.1 5.6 5.0 11.1 16.0 10.8 5.9 9.4 13.7 4.1 14.5 6.5 5.5 4.7 10.5 3.2 1.9 2.4 1.4 0.5 0.0 0.9 1.2 1.3 2.7 1.2 1.6 0.8 0.8 1.6 0.8 0.1 2.0 3.3 6.5 1.8 0.7 53.6 63.1 52.1 60.5 52.1 44.4 58.0 55.1 52.7 51.6 53.2 75.5 19.0 9.6 8.8 22.5 5.8 30.0 28.4 21.4 19.9 11.4 30.0 37.1 32.8 44.3 13.4 14.7 0.0 2.5 9.9 40.0 82.2 22.1 37.3 25.2 17.8 14.6 21.0 6.1 39.2 8.7 5.6 22.2 61.7 59.9 1.3 4.9 15.4 21.3 6.8 33.7 17.6 48.0 73.2 3.2 11.0 26.6 20.2 5.8 48.0 9.4 2.7 11.7 11.3 21.1 134.8 10.3 42.4 18.4 18.6 55.5 43.7 86.7 12.2 11.3 26.3 17.4 17.0 5.0 11.4 30.0 29.1 1.2 6.5 18.5 44.7 99.0 RAB40C "RARL, RASL8C" ENSG00000197562 "RAB40C, member RAS oncogene family" Q96S21 16 589357-629272 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 58.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 14.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 14.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076172 Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 50: Non-specific - Ribosome" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA076172: " "unprognostic (8.04e-2)" "unprognostic (3.63e-1)" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (5.38e-3)" "unprognostic (1.07e-2)" "prognostic unfavorable (1.18e-4)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (5.78e-2)" "unprognostic (3.45e-2)" "unprognostic (2.90e-1)" "unprognostic (1.37e-3)" "unprognostic (3.89e-2)" "unprognostic (6.20e-2)" "unprognostic (7.48e-2)" "unprognostic (4.00e-3)" 10.5 8.0 7.4 4.5 10.0 5.8 11.6 7.1 17.7 13.2 0.0 20.3 13.3 13.0 5.1 20.4 12.2 4.5 12.5 10.9 2.0 13.9 12.8 13.3 4.1 3.4 2.6 12.1 38.5 5.1 21.4 6.6 3.2 17.5 4.4 1.9 14.3 5.9 18.8 58.0 13.6 4.4 1.5 7.9 19.3 13.8 4.0 10.2 10.6 6.2 2.6 18.3 16.1 8.8 7.7 16.3 9.4 13.2 5.3 6.6 12.6 10.1 4.7 8.0 6.5 14.7 13.7 8.8 10.5 6.0 7.1 17.1 5.8 8.3 1.6 9.3 9.8 4.9 11.3 10.5 9.4 9.9 8.9 5.6 17.9 6.4 6.7 5.6 6.6 10.3 11.2 8.8 3.5 22.7 9.6 18.0 10.9 13.5 9.4 15.4 6.7 14.1 4.7 10.9 12.8 10.3 11.1 24.1 9.4 4.3 17.8 19.6 8.2 8.4 11.8 11.3 6.1 8.4 8.6 11.0 5.5 13.4 8.9 1.1 2.8 14.0 0.4 1.8 1.9 1.1 1.4 1.5 1.6 0.7 1.0 0.7 4.8 0.8 0.8 0.7 0.6 1.3 7.4 10.0 7.1 17.7 10.9 2.0 3.4 2.6 3.2 1.5 4.0 8.8 7.1 9.6 15.7 20.5 4.3 17.5 9.9 11.3 18.2 11.4 9.8 7.9 6.3 8.6 10.4 11.0 8.4 26.6 7.7 33.2 7.9 6.2 4.0 12.1 7.1 5.4 10.8 5.2 44.5 12.5 15.3 4.7 23.4 12.7 7.0 11.2 7.5 16.2 9.4 16.8 18.6 16.5 24.4 6.1 4.1 6.6 5.0 4.5 7.2 10.3 7.5 8.4 7.2 10.6 14.8 10.4 21.3 6.4 2.5 10.8 38.2 9.7 11.2 3.3 0.0 5.6 5.8 17.1 13.9 24.8 31.1 56.8 4.6 7.2 18.7 8.6 RAB44 "dJ431A14.3, RASD3, RASL13" ENSG00000255587 "RAB44, member RAS oncogene family" Q7Z6P3 6 36697826-36733184 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "bone marrow: 58.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 4.4;granulocytes: 14.5;monocytes: 2.3;Squamous epithelial cells: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "basophil: 10.6;eosinophil: 7.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 10.6" "Cell line enhanced" "Detected in some" "HEL: 21.9;HL-60: 30.9;HMC-1: 88.9;NB-4: 76.7;THP-1: 30.1;U-937: 60.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA079390 Approved Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Vesicles "HPA079390: " "unprognostic (8.86e-2)" "unprognostic (5.58e-3)" "unprognostic (5.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.37e-1)" "unprognostic (1.28e-3)" "unprognostic (9.56e-2)" "unprognostic (6.35e-4)" "unprognostic (1.45e-1)" "unprognostic (1.13e-1)" "unprognostic (7.13e-3)" "unprognostic (2.57e-1)" "unprognostic (3.02e-2)" "unprognostic (3.13e-3)" "unprognostic (3.03e-2)" "unprognostic (9.67e-3)" "unprognostic (5.79e-2)" 0.5 0.0 0.0 0.6 0.1 58.9 0.4 0.0 0.1 0.4 0.0 0.4 0.6 0.3 0.2 0.5 0.5 0.8 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.2 0.1 0.1 0.5 0.9 0.4 0.0 0.5 0.7 0.0 0.0 0.1 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 30.9 88.9 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 76.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.7 0.0 10.6 0.8 7.2 0.0 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.2 4.4 0.7 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.3 0.0 1.3 0.3 0.2 0.0 0.3 0.0 0.5 14.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.3 0.0 1.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.3 0.0 0.0 2.2 0.0 0.0 0.4 0.1 0.0 0.1 RAB5B ENSG00000111540 "RAB5B, member RAS oncogene family" P61020 12 55973913-55996683 "Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010224, HPA068337" Approved Supported Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "CAB010224: AB_2175453, HPA068337: AB_2685974" "prognostic unfavorable (2.24e-5)" "unprognostic (1.86e-1)" "unprognostic (1.91e-1)" "unprognostic (7.66e-3)" "unprognostic (2.09e-1)" "unprognostic (8.42e-2)" "unprognostic (9.16e-3)" "unprognostic (3.09e-1)" "unprognostic (3.13e-1)" "unprognostic (8.31e-3)" "unprognostic (8.64e-2)" "unprognostic (2.26e-1)" "unprognostic (2.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.74e-1)" "unprognostic (2.85e-1)" "unprognostic (2.49e-1)" 50.9 54.4 95.4 39.4 102.3 35.0 68.2 106.2 96.8 76.8 76.5 72.2 52.4 73.8 92.4 99.8 75.7 55.8 87.2 93.1 99.5 70.1 68.8 72.9 44.5 103.5 105.6 85.4 47.9 112.1 31.4 63.4 106.0 74.6 80.6 72.9 61.7 94.6 100.6 92.4 50.4 79.9 103.6 48.1 67.0 57.1 99.9 64.0 64.6 127.6 76.0 65.6 69.6 112.9 62.3 39.1 80.2 59.4 128.5 115.9 72.1 56.1 102.3 68.3 57.5 67.5 76.7 34.7 65.5 107.6 50.3 44.8 51.4 77.8 63.3 44.1 39.5 39.3 53.1 38.6 94.5 33.2 61.6 94.9 142.7 64.2 54.2 153.0 87.0 42.2 36.2 99.3 87.3 42.3 42.6 51.9 35.8 51.5 35.2 36.5 49.9 45.1 128.2 100.7 40.0 35.6 73.1 72.4 89.0 88.3 104.6 102.5 72.3 44.5 32.5 32.8 22.2 56.4 46.9 21.8 71.5 30.7 38.4 18.5 10.1 32.6 11.1 9.3 10.3 8.9 9.0 9.9 8.0 6.9 10.2 8.0 27.4 7.6 10.6 8.0 7.6 8.9 95.4 102.3 106.2 96.8 93.1 99.5 103.5 105.6 106.0 103.6 99.9 112.9 24.4 57.7 37.1 13.1 26.7 51.7 26.5 34.0 35.3 33.3 54.4 38.2 53.2 55.8 34.0 42.3 52.1 44.0 29.1 88.1 35.2 49.4 11.1 24.1 22.8 30.8 38.9 29.8 21.4 37.1 42.8 33.1 37.2 33.9 19.7 34.1 42.1 86.0 31.1 16.8 23.4 51.1 16.2 46.4 52.3 27.7 53.4 25.4 35.6 11.2 64.7 41.6 32.0 11.1 26.3 71.3 44.4 59.5 27.1 57.0 44.7 35.9 23.9 31.6 59.2 31.9 33.2 36.8 25.6 64.7 89.2 88.0 25.0 23.4 42.7 65.8 RABEP1 "neurocrescin, RAB5EP, rabaptin-5, RABPT5" ENSG00000029725 "Rabaptin, RAB GTPase binding effector protein 1" Q15276 17 5282265-5386340 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004549, HPA019669, HPA024235, HPA024691" Supported Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB004549: AB_628192, HPA019669: AB_1856019, HPA024235: AB_1856020, HPA024691: AB_1856021" "unprognostic (3.22e-1)" "unprognostic (2.90e-2)" "unprognostic (2.45e-1)" "unprognostic (8.75e-3)" "unprognostic (1.64e-1)" "unprognostic (8.25e-2)" "unprognostic (3.71e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (7.73e-2)" "prognostic favorable (6.43e-4)" "unprognostic (1.14e-1)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (2.60e-1)" "unprognostic (1.00e-1)" "unprognostic (9.00e-3)" 30.1 23.6 39.1 23.2 45.8 17.1 43.9 41.0 49.3 22.2 32.0 21.1 16.5 26.8 25.1 18.5 16.7 21.7 32.4 37.9 46.7 23.5 32.8 19.5 33.5 43.1 44.8 21.7 18.0 48.0 19.7 30.8 44.2 31.0 20.7 58.2 22.7 21.8 68.5 16.3 18.9 27.5 43.5 28.3 24.0 18.8 43.7 37.3 25.8 52.4 40.3 23.1 15.2 50.7 45.5 57.5 59.6 33.3 60.9 60.5 31.2 58.3 44.5 61.8 58.5 51.4 19.7 98.3 46.0 61.2 35.0 35.9 87.8 50.0 86.4 60.7 75.0 60.9 73.1 39.4 56.4 41.3 37.9 47.2 33.3 59.6 76.5 37.7 54.4 49.9 52.3 48.3 54.2 32.7 66.1 30.4 26.8 25.8 24.9 61.2 70.8 32.4 30.6 43.1 25.3 39.4 52.4 52.8 49.5 52.3 95.9 17.2 46.9 53.1 24.2 52.6 69.6 26.9 31.0 52.4 41.2 62.3 37.5 14.9 21.1 22.4 25.0 22.7 21.9 80.4 19.5 24.0 22.6 96.7 24.6 21.5 30.4 22.6 50.9 35.0 20.0 16.6 39.1 45.8 41.0 49.3 37.9 46.7 43.1 44.8 44.2 43.5 43.7 50.7 36.4 35.3 45.1 57.5 53.8 24.0 30.1 17.0 25.6 51.5 87.3 46.0 91.1 14.3 32.9 18.4 39.6 39.7 47.2 18.6 41.1 30.4 7.6 19.8 55.5 37.9 16.3 58.3 123.7 23.8 35.0 38.5 23.4 25.3 12.6 47.0 34.2 31.7 89.8 35.3 115.9 17.1 30.5 32.1 38.2 6.0 33.8 36.5 30.2 90.9 32.8 89.7 63.8 78.4 114.1 28.3 65.5 28.2 28.2 52.8 16.5 38.1 19.0 52.5 26.3 34.3 47.7 82.2 75.7 25.5 20.3 25.9 34.4 61.2 18.9 33.6 RABGGTB ENSG00000137955 "Rab geranylgeranyltransferase subunit beta" P53611 1 75786197-75795086 "Enzymes, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026585, HPA027167, HPA030793" Approved Supported Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA026585: AB_1856026, HPA027167: AB_1856027, HPA030793: " "unprognostic (4.83e-2)" "unprognostic (3.04e-1)" "unprognostic (2.09e-2)" "unprognostic (2.45e-2)" "unprognostic (9.02e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (9.80e-5)" "unprognostic (9.62e-3)" "unprognostic (2.93e-1)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (6.95e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (6.05e-2)" "unprognostic (1.56e-1)" "unprognostic (6.77e-2)" "unprognostic (3.89e-1)" 37.5 56.5 41.0 20.3 44.9 18.3 41.4 44.7 52.8 31.4 40.4 33.9 33.3 24.6 23.6 35.2 28.1 21.4 49.6 40.0 44.8 75.9 67.2 29.0 26.9 44.8 43.6 38.1 67.7 37.5 25.1 31.5 44.8 27.5 29.3 41.2 32.0 23.0 79.7 21.7 24.9 23.0 47.1 29.1 33.9 15.3 43.6 30.6 30.5 84.0 31.3 37.3 30.4 47.9 74.8 40.2 68.6 31.4 85.2 108.8 43.8 99.5 68.2 91.6 70.4 97.3 17.6 68.2 101.3 55.7 146.0 46.0 178.3 77.7 133.8 67.1 48.3 58.0 66.5 158.0 106.6 74.8 32.9 67.5 165.1 84.3 95.4 125.6 75.8 59.7 96.9 65.7 109.9 30.8 61.5 81.4 64.5 53.3 78.0 49.2 114.5 29.9 69.9 41.7 43.5 39.1 24.1 123.6 231.0 58.8 26.1 69.8 77.5 59.6 67.0 142.1 199.5 41.9 127.1 46.4 67.5 60.3 27.0 8.4 7.2 4.7 7.7 11.3 9.3 9.5 7.7 7.2 12.3 5.9 9.4 9.3 1.1 6.3 8.1 11.3 7.7 4.0 41.0 44.9 44.7 52.8 40.0 44.8 44.8 43.6 44.8 47.1 43.6 47.9 35.3 35.3 44.3 12.7 83.3 127.7 59.4 132.6 66.0 22.6 58.5 45.6 71.1 72.9 86.0 27.6 20.9 45.9 65.7 38.6 103.7 44.9 1.6 36.1 42.5 45.8 89.8 41.6 17.1 51.8 60.3 48.6 57.6 40.4 70.5 26.5 41.7 68.6 61.2 32.0 17.8 62.2 75.3 61.3 91.4 4.4 32.3 54.8 58.7 9.4 52.0 36.5 32.0 14.6 21.9 44.1 46.0 33.4 78.8 84.8 58.4 206.5 45.8 22.3 6.6 40.1 59.8 20.1 14.0 73.6 142.9 53.5 60.2 37.5 69.6 88.7 RAMP2 ENSG00000131477 "Receptor activity modifying protein 2" O60895 17 42758447-42763041 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 1066.8;Endothelial cells: 562.9;Hepatic stellate cells: 344.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 21 "dendritic cells: 2.9" "Cell line enhanced" "Detected in many" "ASC diff: 120.4;EFO-21: 80.5;HUVEC TERT2: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052020 Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA052020: AB_2681697" "unprognostic (8.64e-2)" "unprognostic (2.12e-2)" "unprognostic (8.03e-2)" "unprognostic (1.16e-2)" "unprognostic (5.24e-2)" "unprognostic (4.13e-3)" "unprognostic (2.68e-2)" "unprognostic (1.04e-1)" "unprognostic (4.50e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (6.79e-2)" "unprognostic (1.28e-2)" "unprognostic (6.96e-3)" "unprognostic (4.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.25e-1)" 190.0 29.0 60.4 19.2 61.8 0.1 168.9 61.7 72.3 100.7 67.7 35.7 12.5 63.1 27.8 25.1 51.7 39.6 123.2 59.3 65.8 70.5 16.7 163.3 26.2 65.7 68.1 33.0 17.1 23.8 20.8 97.0 72.7 42.1 21.1 4.1 45.9 27.5 43.3 55.9 44.1 72.6 62.7 40.2 33.9 11.9 66.6 11.4 71.7 98.7 24.5 45.9 49.6 62.4 0.1 1.1 4.9 0.1 120.4 6.2 4.0 0.9 2.1 10.2 4.9 11.5 0.1 0.0 80.5 3.0 0.5 0.0 4.6 0.1 8.9 0.0 0.2 0.0 0.7 3.7 3.0 0.0 0.0 4.2 0.1 1.8 0.4 3.5 37.6 1.5 0.1 0.2 0.6 0.0 0.6 0.8 23.3 0.0 0.0 0.1 0.1 0.0 0.6 0.6 4.8 9.8 2.9 0.0 17.3 4.8 1.2 3.2 6.7 19.3 7.1 0.4 2.4 0.0 0.1 0.3 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 60.4 61.8 61.7 72.3 59.3 65.8 65.7 68.1 72.7 62.7 66.6 62.4 1066.8 0.0 5.7 1.6 6.2 34.4 5.4 0.9 9.6 0.6 24.0 24.8 2.2 0.0 1.0 3.7 0.0 1.1 3.7 0.1 3.9 0.6 1.6 22.2 52.8 562.9 4.2 0.0 0.2 0.7 1.7 126.9 3.1 38.5 0.0 1.4 344.8 1.3 3.4 0.0 1.0 0.2 20.3 8.4 40.5 3.6 38.8 4.1 23.2 45.0 2.6 15.5 0.0 1.5 0.3 0.0 0.0 21.8 5.2 4.8 0.0 1.0 0.1 1.8 6.6 10.5 26.3 26.6 59.1 2.6 27.6 1.5 4.0 14.0 0.1 4.3 RANBP6 ENSG00000137040 "RAN binding protein 6" O60518 9 6011025-6015625 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043748, HPA052684" Approved Supported Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Vesicles "HPA043748: AB_10796796, HPA052684: AB_2681913" "unprognostic (1.47e-2)" "unprognostic (8.86e-2)" "unprognostic (1.70e-1)" "unprognostic (6.01e-2)" "unprognostic (3.63e-2)" "unprognostic (1.30e-1)" "unprognostic (3.37e-1)" "unprognostic (3.21e-2)" "unprognostic (1.34e-1)" "unprognostic (8.22e-2)" "unprognostic (3.81e-2)" "unprognostic (1.89e-2)" "prognostic favorable (1.34e-7)" "unprognostic (2.42e-1)" "unprognostic (1.91e-1)" "unprognostic (3.04e-1)" "unprognostic (2.61e-1)" 8.6 11.4 8.3 12.9 8.8 31.0 11.4 11.5 12.4 7.7 18.4 7.1 7.5 8.8 7.0 7.9 7.3 7.6 12.4 9.3 10.8 13.4 15.2 8.4 17.0 11.2 9.7 9.6 7.8 13.6 5.0 8.9 11.9 9.7 7.1 21.6 8.6 8.5 16.3 9.9 8.6 10.3 9.2 13.1 11.1 5.9 10.0 19.6 12.0 16.1 16.2 8.7 5.6 10.3 25.1 13.6 27.2 23.4 23.6 18.6 14.6 30.9 21.9 26.8 21.6 7.5 7.7 33.5 8.4 24.7 13.1 14.0 24.2 28.2 29.7 80.1 13.9 88.3 53.0 15.6 13.9 34.2 17.9 20.2 15.2 16.5 16.3 21.1 31.3 30.1 6.9 27.3 25.8 8.4 24.3 54.8 12.3 9.0 11.0 25.6 16.7 15.7 28.1 17.6 13.2 19.9 14.7 11.0 8.7 22.3 17.7 23.0 37.6 25.1 14.9 12.4 29.4 16.3 27.8 31.5 14.4 19.8 9.3 5.1 4.5 3.7 2.6 6.3 2.5 2.5 3.8 2.8 2.7 1.9 4.4 4.2 1.3 2.8 5.2 3.1 5.2 2.9 8.3 8.8 11.5 12.4 9.3 10.8 11.2 9.7 11.9 9.2 10.0 10.3 11.3 9.6 8.1 8.8 11.5 10.3 6.6 10.1 13.1 18.0 8.1 5.6 24.4 8.6 16.3 11.0 2.1 8.8 12.0 4.1 7.9 8.6 1.6 12.2 16.5 13.1 9.5 8.6 15.9 10.9 4.1 8.3 16.8 17.7 10.8 10.1 10.0 13.7 4.4 11.8 19.0 3.2 2.0 10.5 6.0 1.2 6.5 7.2 1.8 8.4 7.2 15.9 9.2 3.0 20.5 7.5 3.8 6.8 11.8 5.7 1.8 12.5 8.7 23.1 0.0 11.6 10.2 10.1 9.3 9.8 9.5 6.6 13.3 12.7 4.8 7.3 RAPGEF1 "C3G, GRF2" ENSG00000107263 "Rap guanine nucleotide exchange factor 1" Q13905 9 131576770-131740074 "Plasma proteins, Predicted intracellular proteins" Neurogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 228.6" "Cell type enhanced" "Detected in all" "Horizontal cells: 131.2;Langerhans cells: 108.6;Microglial cells: 123.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006426, HPA075984" Enhanced Supported Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA006426: AB_1856070, HPA075984: AB_2686771" "unprognostic (1.00e-1)" "unprognostic (8.19e-2)" "unprognostic (2.12e-2)" "unprognostic (2.43e-2)" "unprognostic (2.34e-1)" "unprognostic (2.38e-1)" "unprognostic (4.11e-2)" "unprognostic (1.74e-1)" "unprognostic (5.50e-2)" "unprognostic (6.04e-2)" "unprognostic (1.94e-2)" "unprognostic (1.62e-1)" "prognostic favorable (1.18e-5)" "unprognostic (5.66e-2)" "unprognostic (1.99e-2)" "unprognostic (1.49e-1)" "unprognostic (3.73e-2)" 37.3 24.0 41.4 53.9 72.6 53.2 26.8 27.0 37.1 20.4 37.9 31.9 23.9 25.6 8.0 23.6 25.5 23.7 57.8 40.8 40.2 23.0 23.0 43.3 56.1 35.8 36.9 16.3 47.8 20.1 16.4 56.4 32.3 21.5 23.4 27.5 20.2 21.4 228.6 21.9 35.3 30.4 25.6 41.9 29.1 15.9 43.8 35.1 22.7 104.8 63.1 25.8 18.2 20.2 34.5 39.4 39.1 39.6 39.1 42.0 149.2 29.0 59.0 33.0 23.6 49.0 22.1 61.9 35.6 58.8 70.7 61.4 45.1 40.5 16.4 144.6 18.6 18.3 67.2 26.2 32.8 76.1 80.4 32.2 73.0 43.3 51.0 33.1 60.4 70.8 49.7 119.1 43.4 35.7 54.0 27.0 39.6 34.1 35.2 53.0 91.0 86.8 14.9 41.1 33.0 32.9 42.5 39.8 42.3 39.0 38.1 63.1 64.4 88.1 36.7 56.4 44.7 39.8 37.3 122.0 41.9 32.0 21.6 3.1 1.2 1.6 3.4 2.2 2.0 4.9 2.3 2.3 1.4 2.9 0.5 1.5 1.3 1.3 2.4 1.6 1.8 1.6 41.4 72.6 27.0 37.1 40.8 40.2 35.8 36.9 32.3 25.6 43.8 20.2 73.5 6.4 13.8 27.1 35.6 18.7 9.3 10.9 5.2 19.5 10.8 13.5 16.2 14.3 12.3 5.5 14.6 22.7 49.7 23.3 5.9 8.2 2.6 13.0 9.4 43.0 12.1 1.7 47.5 18.6 35.3 11.8 17.9 17.8 20.3 14.0 22.5 17.4 26.4 131.2 66.6 14.9 8.2 23.9 108.6 2.5 8.7 51.6 32.0 123.7 59.8 19.7 27.8 61.3 24.7 17.1 19.1 12.0 88.0 11.7 16.8 9.2 16.7 13.4 6.6 13.4 10.3 5.1 11.8 5.6 11.4 51.7 31.0 5.8 14.0 10.8 RASA2 GAP1M ENSG00000155903 "RAS p21 protein activator 2" Q15283 3 141487027-141615344 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 196.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035374, HPA035375" Approved Approved Vesicles "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Vesicles "HPA035374: AB_10602122, HPA035375: AB_2674596" "unprognostic (1.85e-1)" "unprognostic (8.11e-2)" "unprognostic (1.48e-1)" "unprognostic (2.38e-2)" "unprognostic (1.18e-1)" "unprognostic (3.36e-3)" "unprognostic (9.62e-3)" "unprognostic (2.57e-1)" "unprognostic (1.38e-1)" "unprognostic (9.21e-2)" "unprognostic (4.23e-2)" "unprognostic (8.93e-2)" "prognostic unfavorable (7.62e-7)" "unprognostic (1.17e-1)" "unprognostic (2.56e-1)" "unprognostic (1.61e-1)" "prognostic favorable (4.34e-5)" 7.3 4.7 5.1 15.4 6.0 21.9 10.0 7.1 6.4 9.8 3.2 6.6 5.3 8.4 7.3 7.3 7.8 6.7 4.6 5.3 4.9 5.8 5.1 9.7 21.3 4.0 3.6 9.7 5.2 4.4 6.2 8.3 3.5 6.5 7.2 14.6 8.1 5.0 3.8 11.2 8.5 6.0 3.1 12.4 5.4 4.7 4.7 13.3 6.0 3.3 17.2 8.8 8.8 5.6 24.6 4.5 9.5 7.2 10.2 12.6 13.5 17.4 34.0 11.0 13.5 10.5 7.9 15.6 11.7 15.2 10.6 10.0 6.8 7.5 20.0 8.5 6.7 8.4 3.8 3.8 5.4 16.1 21.0 7.3 6.6 10.0 11.8 13.3 14.1 13.1 7.7 19.7 11.0 3.6 21.2 13.0 11.1 8.1 3.2 7.9 16.0 19.5 10.9 8.7 3.3 6.9 13.8 12.1 13.0 9.8 6.0 12.0 11.9 12.9 5.9 18.1 7.8 31.9 10.0 20.9 11.3 10.8 6.4 12.8 4.9 5.3 14.8 5.0 14.8 8.9 13.2 15.3 4.6 13.5 21.6 17.2 19.2 15.7 8.9 3.6 13.2 8.0 5.1 6.0 7.1 6.4 5.3 4.9 4.0 3.6 3.5 3.1 4.7 5.6 24.2 44.8 23.6 59.4 55.1 21.5 52.0 15.8 21.1 16.2 22.0 17.5 7.4 8.6 21.4 12.9 37.5 20.0 104.9 21.7 1.9 16.8 120.3 26.3 19.7 22.7 15.7 17.5 196.9 16.5 6.6 20.4 11.2 60.7 31.6 29.6 20.3 9.6 12.5 30.3 123.1 15.2 8.2 32.5 24.6 12.7 13.7 34.3 12.4 94.6 19.8 15.3 68.0 112.1 94.4 31.8 21.7 14.3 94.9 53.4 10.4 9.1 15.5 50.7 6.6 26.4 27.2 28.2 15.3 17.5 27.4 13.1 88.3 4.6 18.7 62.5 RASL10B "RRP17, VTS58635" ENSG00000270885 "RAS like family 10 member B" Q96S79 17 35731639-35743521 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.3;skeletal muscle: 31.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 13.8;Early spermatids: 10.4;Late spermatids: 34.6;Muller glia cells: 29.0" "Cancer enhanced" "Detected in many" "testis cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 24.3;HHSteC: 26.7;NTERA-2: 41.3;REH: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046842, HPA057092" Enhanced Approved Vesicles NA NA "Cluster 47: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA046842: AB_2679835, HPA057092: AB_2683332" "unprognostic (5.78e-2)" "unprognostic (2.15e-2)" "unprognostic (2.36e-2)" "prognostic unfavorable (6.38e-6)" "unprognostic (8.60e-2)" "unprognostic (1.24e-1)" "unprognostic (2.69e-2)" "unprognostic (4.98e-2)" "unprognostic (1.97e-2)" "unprognostic (7.13e-2)" "unprognostic (2.61e-2)" "unprognostic (3.18e-2)" "unprognostic (1.71e-6)" "unprognostic (2.41e-3)" "unprognostic (1.00e-1)" "unprognostic (1.32e-2)" "unprognostic (9.60e-3)" 15.4 1.7 25.9 0.1 32.3 0.0 11.3 8.7 25.6 3.9 7.6 1.9 0.7 2.8 0.6 0.4 3.9 0.7 19.3 26.5 18.1 3.0 2.1 1.2 0.1 16.5 19.2 3.7 4.9 5.2 6.7 2.8 18.0 2.9 0.1 9.0 9.1 14.7 31.5 0.8 1.2 0.7 13.2 0.3 1.8 3.0 17.5 0.4 1.7 0.9 0.1 1.4 2.3 12.9 0.0 0.3 6.3 0.0 1.1 0.6 1.8 1.2 0.8 4.3 3.6 8.1 0.0 0.0 0.7 0.2 0.0 0.0 24.3 0.0 1.5 0.0 8.0 0.0 4.1 9.3 26.7 0.0 0.0 19.5 1.5 1.5 0.0 3.4 0.0 13.2 5.5 0.0 0.3 0.5 11.6 0.0 41.3 0.0 0.0 20.8 11.1 18.5 0.0 0.0 18.3 17.8 1.2 0.4 1.7 17.8 2.3 1.2 0.0 2.0 14.5 0.1 0.5 0.0 0.0 5.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 32.3 8.7 25.6 26.5 18.1 16.5 19.2 18.0 13.2 17.5 12.9 0.3 0.0 0.5 0.3 0.0 0.1 0.5 0.0 0.0 3.9 2.7 1.4 13.8 4.3 0.0 1.8 2.1 0.0 0.0 0.0 0.0 1.3 10.4 1.0 0.7 0.7 0.0 0.0 2.6 0.0 0.0 1.9 0.0 1.4 0.0 2.8 0.0 6.7 0.2 6.7 4.9 0.2 0.0 0.6 0.0 34.6 2.1 0.1 0.0 1.0 0.0 29.0 0.0 0.5 0.5 0.3 0.0 3.0 0.0 0.6 0.4 0.1 0.0 1.2 0.0 1.5 2.3 4.8 0.9 0.0 0.0 0.3 0.1 7.0 0.4 0.2 RBMS3 ENSG00000144642 "RNA binding motif single stranded interacting protein 3" Q6XE24 3 28574791-30010391 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 331.1;Inhibitory neurons: 655.9;Microglial cells: 1013.7;Oligodendrocyte precursor cells: 229.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 5.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 9 "dendritic cells: 3.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 20.7;WM-115: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034719 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034719: AB_10670172" "unprognostic (8.39e-2)" "unprognostic (2.54e-2)" "unprognostic (1.02e-1)" "unprognostic (7.08e-2)" "unprognostic (2.29e-1)" "unprognostic (1.33e-1)" "unprognostic (3.13e-2)" "unprognostic (4.95e-2)" "unprognostic (1.08e-1)" "unprognostic (3.90e-2)" "unprognostic (1.90e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (2.25e-3)" "unprognostic (3.81e-2)" "unprognostic (8.48e-2)" "unprognostic (3.24e-4)" 15.8 8.6 6.5 2.1 7.2 0.1 12.2 9.5 5.8 9.9 12.0 8.1 1.4 6.2 6.7 3.1 9.8 6.7 14.3 2.1 21.4 5.1 3.7 12.6 2.7 12.6 15.7 11.6 2.0 4.9 3.2 10.4 9.0 6.4 2.6 0.4 4.7 8.7 6.4 3.8 4.0 4.5 6.3 6.6 4.3 2.2 11.1 5.5 15.3 10.8 1.7 8.1 7.3 2.6 2.2 0.2 10.2 0.1 19.6 12.5 0.0 5.7 3.6 5.9 6.8 0.0 0.4 0.0 6.1 20.7 1.8 0.2 0.5 3.8 10.9 0.0 1.1 5.9 8.7 0.0 19.9 0.1 0.0 11.8 2.6 10.5 12.3 8.4 7.9 0.0 0.0 0.0 7.4 0.0 0.1 0.0 0.3 0.0 0.4 0.4 7.5 0.0 2.2 0.0 0.0 19.4 13.7 0.0 0.7 4.6 0.0 0.0 17.1 11.1 11.6 13.5 11.7 0.0 0.0 0.8 1.5 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.9 0.3 0.0 6.5 7.2 9.5 5.8 2.1 21.4 12.6 15.7 9.0 6.3 11.1 2.6 100.9 118.6 18.8 331.1 0.6 8.3 25.5 23.0 2.2 0.4 2.7 19.8 16.2 31.5 21.3 9.2 0.0 16.4 5.9 0.0 0.0 5.3 35.1 2.8 7.0 54.4 0.0 0.0 20.7 1.2 3.0 96.8 2.0 4.6 5.1 19.8 129.9 1.9 2.8 0.0 655.9 0.0 6.1 30.3 14.1 18.8 159.7 2.7 7.2 1013.7 0.6 0.0 0.0 229.2 8.9 0.4 0.0 110.6 0.1 24.3 0.0 2.9 10.5 0.0 111.7 154.6 73.5 1.2 1.5 2.4 7.2 9.6 2.9 22.4 0.0 4.7 RBSN ZFYVE20 ENSG00000131381 "Rabenosyn, RAB effector" Q9H1K0 3 15070073-15099163 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044878 Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 59: Non-specific - Transcription" Vesicles "HPA044878: AB_10967610" "unprognostic (6.76e-2)" "unprognostic (2.18e-1)" "unprognostic (3.00e-3)" "unprognostic (1.00e-1)" "unprognostic (8.06e-2)" "unprognostic (3.79e-3)" "unprognostic (1.09e-3)" "unprognostic (1.72e-2)" "unprognostic (3.57e-1)" "unprognostic (1.90e-2)" "unprognostic (2.00e-2)" "unprognostic (9.34e-2)" "unprognostic (2.38e-3)" "unprognostic (4.45e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-1)" "unprognostic (1.78e-1)" 9.0 7.0 12.5 6.7 12.5 18.2 7.7 10.2 13.0 9.1 1.1 10.7 4.7 9.3 7.1 8.9 8.7 5.4 9.8 13.4 11.4 5.4 8.4 8.4 6.6 12.1 12.5 12.7 5.9 9.7 6.1 7.9 11.1 7.4 5.3 13.6 5.9 9.0 13.1 10.2 7.1 9.0 12.8 7.7 7.8 6.6 13.0 5.5 11.2 9.9 6.1 9.1 7.5 11.8 11.2 16.0 12.8 16.6 13.8 10.2 33.9 12.0 11.5 14.1 12.7 9.7 6.5 7.8 6.8 15.9 8.2 7.0 16.5 14.5 12.4 9.9 14.6 8.9 19.7 8.0 9.5 9.0 9.4 11.1 16.1 18.1 12.0 8.3 11.6 8.7 13.5 8.9 10.8 14.7 4.9 4.5 11.0 7.1 12.7 6.4 14.6 8.6 7.3 12.6 3.4 12.0 14.7 8.9 10.7 9.4 22.8 6.5 14.2 12.7 13.3 12.5 17.1 7.9 12.6 9.2 12.2 10.0 12.2 8.1 4.6 11.1 4.4 6.4 3.9 4.4 6.1 5.5 3.8 7.4 7.7 5.2 11.7 3.1 5.6 3.6 4.3 2.7 12.5 12.5 10.2 13.0 13.4 11.4 12.1 12.5 11.1 12.8 13.0 11.8 10.4 16.0 19.0 19.6 9.2 0.0 6.7 0.0 6.8 21.6 7.6 7.0 20.4 8.6 9.9 3.7 22.9 10.4 8.4 6.0 5.9 8.4 17.4 6.4 11.1 12.4 1.2 9.5 21.8 9.6 9.6 14.6 10.2 8.8 10.1 16.4 14.6 14.0 10.7 21.9 23.9 6.9 0.0 15.8 0.0 18.0 19.0 12.1 0.0 8.4 10.5 15.5 7.2 16.1 25.2 9.6 5.1 14.7 12.1 12.6 8.1 6.9 8.0 23.1 6.6 17.5 10.4 12.4 14.0 11.0 0.0 12.9 9.9 10.6 5.4 10.0 RC3H2 "FLJ20301, FLJ20713, MNAB, RNF164" ENSG00000056586 "Ring finger and CCCH-type domains 2" Q9HBD1 9 122844556-122905359 "Enzymes, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" "Repressor, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042863, HPA062144" Approved Enhanced Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles "HPA042863: AB_2678204, HPA062144: AB_2732677" "unprognostic (6.05e-2)" "unprognostic (7.87e-2)" "unprognostic (7.24e-2)" "unprognostic (1.66e-1)" "unprognostic (4.08e-3)" "unprognostic (2.37e-1)" "unprognostic (2.43e-2)" "unprognostic (3.92e-2)" "unprognostic (1.99e-1)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.21e-1)" "prognostic favorable (5.50e-4)" "unprognostic (1.36e-1)" "unprognostic (1.68e-1)" "unprognostic (2.16e-1)" "unprognostic (1.26e-1)" 11.9 8.9 8.8 12.1 10.8 32.5 10.4 14.0 10.0 13.5 4.4 10.4 9.9 11.9 8.1 13.0 9.7 11.0 13.8 10.9 7.9 12.7 13.4 11.5 18.5 7.1 7.4 11.2 6.8 15.8 9.6 14.6 7.6 9.7 11.2 16.0 9.0 9.1 11.8 10.0 9.4 13.9 7.1 14.1 11.8 11.6 8.0 18.8 12.9 15.3 17.2 14.4 9.0 10.5 17.3 26.2 33.5 18.2 17.4 19.8 17.8 22.0 24.4 25.2 21.8 31.2 18.8 28.8 16.7 29.8 30.1 40.9 35.4 25.1 27.7 13.4 13.5 16.4 44.4 21.3 23.1 19.9 26.5 19.9 25.5 24.3 34.6 22.0 35.6 25.4 24.1 21.6 32.9 23.9 20.2 14.7 17.7 24.9 21.8 19.7 54.8 19.4 25.8 13.9 38.3 25.8 39.2 24.9 21.2 22.8 29.2 17.2 33.9 20.5 17.3 27.7 39.8 14.0 25.4 32.1 22.3 18.2 23.1 10.0 4.6 6.0 6.1 7.3 5.1 4.3 4.8 6.0 4.1 5.8 4.5 4.5 8.0 4.0 6.7 6.5 5.1 2.8 8.8 10.8 14.0 10.0 10.9 7.9 7.1 7.4 7.6 7.1 8.0 10.5 33.8 41.7 32.8 20.9 27.7 11.0 13.6 20.0 20.5 19.2 15.6 10.5 34.8 12.8 17.3 9.2 37.5 15.7 26.6 18.9 3.9 12.0 5.9 27.6 30.9 28.3 23.3 22.7 38.4 11.4 15.2 18.4 23.9 40.1 17.1 21.9 29.6 19.5 9.6 28.6 35.1 19.8 12.2 27.4 19.4 9.5 13.4 21.4 14.2 30.9 26.1 16.9 24.7 35.2 39.3 23.5 9.0 18.0 22.5 24.3 14.8 12.0 17.7 20.2 19.7 16.3 24.1 30.7 17.9 23.3 14.8 23.0 28.8 15.4 14.7 27.3 RDH5 "HSD17B9, RDH1, SDR9C5" ENSG00000135437 "Retinol dehydrogenase 5" Q92781 12 55720367-55724705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Steroid metabolism, Vision" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 94.5;liver: 58.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6;Proximal enterocytes: 49.9;Rod photoreceptor cells: 62.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 28.5;ASC TERT1: 24.3;hTEC/SVTERT24-B: 15.3;hTERT-RPE1: 24.5;LHCN-M2: 15.4;U-87 MG: 26.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063345 Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA063345: AB_2684992" "unprognostic (1.04e-2)" "unprognostic (6.45e-2)" "unprognostic (1.80e-1)" "unprognostic (2.67e-1)" "unprognostic (3.66e-2)" "unprognostic (1.48e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.35e-2)" "unprognostic (4.04e-2)" "unprognostic (4.05e-1)" "unprognostic (1.26e-3)" "unprognostic (7.63e-2)" "unprognostic (8.79e-2)" "unprognostic (3.46e-2)" "unprognostic (2.12e-3)" "unprognostic (3.27e-2)" 94.5 1.8 2.2 4.1 2.5 1.0 34.2 2.2 2.6 2.5 3.5 13.6 18.5 4.2 7.8 3.1 4.6 4.2 9.2 2.0 2.2 9.0 58.9 1.9 1.8 2.7 2.5 2.1 3.5 0.3 1.7 0.6 2.4 4.4 4.4 3.2 3.3 2.2 6.1 2.7 15.5 19.5 2.5 2.2 5.9 2.4 2.8 0.9 2.7 7.6 0.7 5.5 2.2 3.4 0.7 1.4 0.8 0.5 28.5 24.3 0.6 3.8 4.2 0.7 1.4 0.5 7.9 1.0 0.7 2.1 0.2 0.3 0.3 0.1 0.6 1.0 1.3 0.1 2.0 2.1 0.8 0.1 0.3 10.5 1.0 15.3 0.1 24.5 0.3 0.5 0.2 1.3 15.4 0.7 0.4 0.2 0.3 3.7 2.3 0.6 0.4 0.5 0.2 0.8 0.2 1.1 0.2 0.5 3.4 0.2 0.7 0.6 0.5 1.5 1.5 1.1 0.9 1.1 0.5 0.2 26.7 0.4 0.3 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.2 0.5 0.2 0.0 0.2 0.0 0.2 0.3 0.2 0.5 0.0 0.0 2.2 2.5 2.2 2.6 2.0 2.2 2.7 2.5 2.4 2.5 2.8 3.4 2.5 9.6 2.2 0.0 4.6 1.9 4.5 3.9 0.6 24.3 2.7 5.0 3.9 10.0 2.4 1.8 62.6 2.2 5.3 23.5 1.9 2.1 0.8 1.8 2.9 3.7 11.5 0.0 0.0 2.6 1.2 3.9 11.2 1.5 0.0 4.9 3.6 18.4 0.6 16.8 0.0 10.3 0.0 4.5 7.9 2.3 13.4 2.3 5.4 0.0 4.7 8.2 12.3 0.0 0.0 3.6 18.6 6.8 0.7 3.2 49.9 13.0 4.7 62.9 13.1 14.0 9.3 3.9 6.4 0.8 1.7 1.5 4.8 5.3 15.9 3.1 RELL2 "C5orf16, FLJ90583" ENSG00000164620 "RELT like 2" Q8NC24 5 141636950-141641064 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.2;parathyroid gland: 16.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 28.5;Horizontal cells: 65.6;Inhibitory neurons: 28.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 31.7;JURKAT: 32.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077928 Uncertain Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA077928: " "unprognostic (3.27e-2)" "unprognostic (8.46e-2)" "unprognostic (2.12e-1)" "unprognostic (4.95e-3)" "unprognostic (1.91e-3)" "unprognostic (7.12e-2)" "unprognostic (1.11e-2)" "unprognostic (1.05e-1)" "unprognostic (3.69e-2)" "unprognostic (2.12e-2)" "unprognostic (6.76e-4)" "unprognostic (4.17e-2)" "unprognostic (1.85e-2)" "unprognostic (7.85e-2)" "unprognostic (8.74e-3)" "unprognostic (4.31e-2)" "unprognostic (6.58e-2)" 1.0 5.9 14.4 1.3 12.8 1.0 1.3 18.8 38.2 1.6 5.4 1.4 1.5 2.1 0.6 3.5 0.8 1.0 1.0 13.4 19.3 3.7 1.9 3.3 2.5 34.1 18.9 0.8 1.4 16.1 15.7 2.3 31.4 2.1 0.7 3.6 2.7 0.5 0.3 2.7 2.8 0.8 10.6 5.8 1.1 6.0 28.5 4.8 2.8 0.0 2.5 1.5 1.8 17.6 1.6 4.3 4.3 7.7 3.2 1.1 2.0 3.6 6.7 11.4 16.9 16.6 1.6 0.2 1.7 5.4 24.9 7.0 4.1 15.1 2.9 4.7 2.5 10.3 10.0 7.8 5.2 3.5 31.7 2.2 9.3 10.6 7.7 2.5 3.1 32.9 3.4 5.3 2.6 2.1 5.8 1.6 4.8 5.7 2.3 0.4 1.0 6.7 3.6 3.9 7.0 7.6 3.3 15.1 2.7 0.6 5.4 8.4 3.8 8.8 4.1 7.1 6.6 3.2 9.0 23.4 4.5 14.5 5.6 0.0 0.8 0.0 1.6 2.0 0.6 1.4 1.7 1.6 1.3 0.8 1.5 0.8 0.6 0.0 1.4 4.5 3.2 1.2 14.4 12.8 18.8 38.2 13.4 19.3 34.1 18.9 31.4 10.6 28.5 17.6 1.1 0.0 0.6 4.2 6.0 4.6 1.5 2.6 2.8 10.5 2.3 2.4 0.3 1.5 2.0 1.8 12.5 0.2 10.0 4.2 1.9 3.3 1.8 0.3 0.8 2.0 1.2 0.0 28.5 2.5 4.1 0.8 0.5 0.2 0.0 0.4 0.4 0.2 4.2 65.6 28.8 2.4 4.1 4.4 3.5 4.7 0.6 5.1 7.2 4.7 2.3 6.6 5.2 2.5 2.8 2.1 5.0 1.5 1.7 2.7 1.2 5.6 1.9 8.6 0.0 0.3 1.3 17.8 7.5 3.6 4.3 6.2 5.5 0.9 0.9 2.2 REX1BD "C19orf60, FLJ20850, FLJ30108, FLJ34606, FLJ37391" ENSG00000006015 "Required for excision 1-B domain containing" Q96EN9 19 18588685-18592337 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 154.6;Extravillous trophoblasts: 147.6;Hofbauer cells: 258.2;Proximal tubular cells: 222.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 64.5;PC-3: 98.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043414 Approved Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA043414: AB_10797141" "unprognostic (1.12e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (6.78e-3)" "unprognostic (1.22e-1)" "unprognostic (4.87e-3)" "unprognostic (2.52e-2)" "unprognostic (1.45e-1)" "unprognostic (4.60e-1)" "unprognostic (3.10e-1)" "unprognostic (5.50e-3)" "unprognostic (3.24e-2)" "unprognostic (3.19e-2)" "unprognostic (4.02e-2)" "unprognostic (9.27e-2)" "unprognostic (1.48e-1)" "prognostic favorable (8.47e-4)" 42.9 40.7 25.5 5.0 23.8 8.1 41.3 21.7 45.2 40.3 11.9 39.3 6.7 39.6 0.5 31.6 34.0 1.9 76.5 24.3 25.3 48.3 63.5 33.9 2.4 25.9 22.5 38.9 52.8 4.3 32.3 3.6 24.2 40.0 1.0 0.6 33.8 6.1 106.4 42.8 33.8 2.4 22.7 47.6 39.0 10.8 26.3 3.9 27.6 9.2 2.2 39.1 38.1 24.9 18.2 20.6 2.0 3.8 2.6 3.1 64.5 19.2 3.0 4.2 4.9 3.8 21.8 18.7 58.4 3.2 1.7 12.9 0.9 4.6 1.1 19.5 47.1 12.1 7.5 9.8 3.7 11.7 28.7 5.2 5.2 2.2 1.1 1.8 5.4 8.4 16.8 6.8 2.2 26.3 19.9 18.6 29.3 9.5 98.5 21.4 5.5 47.2 7.4 15.0 9.5 34.6 9.1 10.8 25.0 0.8 5.2 7.5 18.5 2.4 18.8 25.5 10.7 52.3 17.3 12.7 18.0 18.9 9.7 100.5 150.9 152.5 148.6 140.1 153.1 126.4 151.4 134.5 146.9 91.6 135.4 128.6 89.4 101.3 132.4 125.8 134.6 143.6 25.5 23.8 21.7 45.2 24.3 25.3 25.9 22.5 24.2 22.7 26.3 24.9 126.2 28.9 41.2 0.0 38.7 0.0 0.0 0.0 0.0 0.0 100.0 136.5 0.0 0.0 21.1 77.3 0.0 127.7 84.0 0.0 154.6 72.9 0.0 52.1 67.8 39.7 0.0 0.0 0.0 116.7 147.6 53.3 0.0 63.7 41.6 122.5 0.0 0.0 258.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.3 0.0 0.0 58.4 0.0 0.0 0.0 0.0 74.7 0.0 0.0 25.9 0.0 0.0 222.4 19.7 0.0 0.0 0.0 43.7 0.0 0.0 0.0 0.0 66.5 50.9 93.6 0.0 0.0 RFFL "CARP-2, CARP2, fring, rififylin, RNF189, RNF34L" ENSG00000092871 "Ring finger and FYVE like domain containing E3 ubiquitin protein ligase" Q8WZ73 17 35005990-35089319 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 93.8" "Cell type enhanced" "Detected in many" "Late spermatids: 109.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 119.5;Karpas-707: 112.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008096, HPA017910, HPA019492" Approved Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "CAB008096: AB_2178607, HPA017910: AB_1856189, HPA019492: AB_1856190" "unprognostic (2.59e-1)" "unprognostic (2.87e-1)" "prognostic favorable (4.92e-4)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" "unprognostic (1.79e-1)" "unprognostic (5.73e-3)" "unprognostic (4.34e-3)" "unprognostic (2.31e-1)" "unprognostic (9.26e-3)" "unprognostic (2.39e-1)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.43e-5)" "unprognostic (1.44e-1)" "unprognostic (1.97e-1)" "unprognostic (8.68e-2)" "unprognostic (1.36e-1)" 9.9 7.1 23.9 17.7 59.5 41.4 12.2 49.2 38.0 11.9 11.6 26.7 28.1 9.6 8.8 35.9 9.3 19.4 8.2 24.3 36.4 17.7 48.3 12.6 17.6 74.2 53.0 8.5 18.8 12.1 6.8 11.9 71.2 18.3 23.2 21.1 13.1 12.7 15.8 7.5 22.8 13.3 48.6 19.2 23.3 26.6 52.2 26.0 39.0 13.1 29.4 20.3 16.2 93.8 22.9 43.4 10.7 15.0 21.6 28.1 6.1 15.6 25.8 15.5 18.7 15.4 50.5 7.0 19.4 21.4 33.0 32.2 18.4 30.8 22.4 119.5 11.2 40.5 11.0 38.6 18.0 20.2 20.0 19.0 18.8 23.7 46.9 22.6 15.6 21.2 18.2 112.2 16.0 8.7 4.9 19.4 15.2 51.1 24.9 17.3 18.7 43.2 22.8 48.6 12.0 15.8 8.9 10.3 9.1 24.4 15.9 27.7 29.7 8.6 14.9 8.7 24.1 41.4 33.0 9.4 36.4 15.8 7.4 28.6 16.2 33.7 16.8 9.3 20.6 7.8 18.5 16.3 10.8 6.9 16.0 14.5 55.3 14.4 9.9 1.3 29.6 15.5 23.9 59.5 49.2 38.0 24.3 36.4 74.2 53.0 71.2 48.6 52.2 93.8 6.5 41.7 27.4 0.0 12.6 6.0 11.9 7.4 5.2 10.6 9.9 3.8 1.3 20.0 17.3 0.0 14.6 9.4 12.1 33.7 1.9 8.4 41.0 13.0 6.8 6.6 15.0 23.8 0.0 15.1 1.7 9.3 23.0 18.1 25.3 5.4 9.3 35.2 7.2 6.7 0.0 26.4 6.1 16.3 16.9 109.1 3.1 16.1 1.8 0.0 22.6 20.8 25.7 0.0 0.0 16.8 19.3 4.5 12.9 28.1 16.7 20.4 11.7 34.9 6.6 15.2 5.7 15.9 10.8 16.2 6.1 5.1 23.7 3.1 18.9 39.5 RFT1 CDG1N ENSG00000163933 "RFT1 homolog" Q96AA3 3 53088483-53130453 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060327, HPA069022" Approved Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA060327: AB_2684253, HPA069022: AB_2732126" "unprognostic (5.74e-2)" "unprognostic (1.31e-1)" "unprognostic (1.35e-3)" "unprognostic (5.16e-3)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (1.09e-1)" "unprognostic (1.22e-1)" "unprognostic (2.70e-1)" "unprognostic (2.81e-2)" "unprognostic (9.26e-2)" "unprognostic (6.48e-2)" "unprognostic (1.96e-1)" "unprognostic (1.22e-1)" "unprognostic (5.06e-2)" "unprognostic (3.54e-2)" 11.8 12.5 5.7 14.5 6.2 8.3 12.5 5.5 6.6 9.0 4.9 11.8 10.3 9.1 13.0 12.1 12.4 10.5 9.0 6.1 5.3 8.7 14.0 9.2 16.7 5.6 5.2 12.5 22.3 15.6 6.2 13.8 5.9 9.3 13.2 4.3 18.0 10.4 5.1 9.9 10.5 11.2 5.5 9.9 10.4 13.5 5.4 14.2 14.6 6.7 15.8 12.6 8.8 8.0 39.1 36.3 24.3 39.0 27.9 29.5 50.6 34.8 32.3 59.2 53.7 35.9 74.6 51.0 21.3 33.5 55.6 40.7 55.4 56.8 51.9 48.4 24.5 50.6 24.8 36.0 48.8 46.7 28.4 31.4 46.8 79.6 57.1 26.2 37.9 52.7 27.1 45.2 39.4 39.6 44.2 27.3 48.8 67.5 47.3 18.1 23.5 77.5 32.8 26.1 13.8 18.7 43.0 30.9 31.2 26.2 23.3 65.5 25.5 54.3 35.2 37.7 69.1 28.6 37.1 38.4 38.9 58.8 58.3 50.2 40.2 18.4 22.2 40.5 22.5 21.2 20.6 22.9 42.9 35.5 23.7 23.7 13.4 23.1 29.4 48.9 20.1 25.7 5.7 6.2 5.5 6.6 6.1 5.3 5.6 5.2 5.9 5.5 5.4 8.0 6.0 3.2 3.7 8.8 8.7 5.0 10.8 18.3 5.2 4.6 7.6 5.5 7.4 11.5 12.6 9.2 4.2 39.4 6.0 5.1 1.9 17.4 1.9 5.6 9.5 8.1 2.4 17.7 9.4 21.1 33.1 9.2 4.1 5.7 2.5 17.8 10.4 10.7 22.0 5.0 8.9 6.4 10.2 9.9 5.0 2.3 8.7 9.8 7.2 9.4 11.7 5.8 3.1 7.5 11.3 12.2 8.8 6.0 19.3 9.1 5.7 5.6 8.3 6.4 0.0 7.0 8.7 10.1 8.9 8.0 4.3 24.2 7.7 22.0 11.7 8.1 RGS17 "RGS-17, RGSZ2" ENSG00000091844 "Regulator of G protein signaling 17" Q9UGC6 6 153004459-153131282 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 41.9;Excitatory neurons: 54.4;Inhibitory neurons: 57.2;Oligodendrocyte precursor cells: 62.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 7.9;hTERT-HME1: 7.0;LHCN-M2: 8.7;RH-30: 6.7;U-87 MG: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022276, HPA056493" Approved Approved Vesicles NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA022276: AB_10794628, HPA056493: AB_2683152" "unprognostic (2.77e-2)" "unprognostic (6.81e-2)" "unprognostic (3.11e-1)" "unprognostic (1.99e-1)" "unprognostic (1.81e-2)" "unprognostic (1.54e-1)" "unprognostic (1.03e-3)" "unprognostic (3.12e-1)" "unprognostic (3.79e-2)" "unprognostic (7.95e-3)" "unprognostic (1.92e-1)" "unprognostic (5.33e-2)" "unprognostic (5.96e-12)" "unprognostic (2.70e-2)" "unprognostic (2.53e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" 0.8 0.3 2.0 0.4 1.8 1.3 0.6 3.5 1.8 1.4 0.0 0.4 0.5 0.5 0.2 1.6 0.5 1.1 0.2 1.8 3.2 0.6 0.1 0.3 0.5 1.7 3.1 0.9 1.0 0.0 1.9 0.1 1.4 1.3 0.4 1.7 0.7 0.3 0.1 0.6 0.5 0.2 2.2 0.3 0.9 0.9 2.8 0.6 2.3 0.0 0.1 0.9 0.7 1.2 0.1 2.0 2.2 0.2 1.0 7.9 0.1 0.2 0.7 0.5 1.3 0.0 0.3 0.3 0.4 0.4 4.2 0.3 2.0 1.9 1.0 0.2 0.3 0.4 0.4 0.1 1.9 0.2 1.0 2.3 0.1 3.3 7.0 1.8 3.8 1.1 0.1 0.3 8.7 0.9 0.1 0.3 1.4 0.1 1.4 0.1 6.7 0.1 2.3 0.9 1.7 4.3 0.1 0.0 0.0 0.4 0.1 0.3 1.8 1.4 1.1 1.5 2.5 0.3 0.1 0.1 9.3 0.1 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 2.0 1.8 3.5 1.8 1.8 3.2 1.7 3.1 1.4 2.2 2.8 1.2 0.3 0.0 0.0 12.7 0.6 0.3 1.2 1.4 0.0 15.9 0.6 0.6 1.0 2.8 7.2 0.0 0.0 0.2 3.7 0.0 0.0 17.1 0.2 0.7 3.5 1.4 41.9 0.4 54.4 0.4 0.2 4.2 4.6 0.8 11.4 0.6 0.0 0.2 0.3 3.3 57.2 0.1 0.0 0.8 3.2 0.6 3.1 0.8 0.0 1.9 0.5 2.7 7.2 62.8 2.2 1.4 1.6 9.1 0.9 6.6 0.0 0.1 3.4 3.5 0.0 3.6 2.4 1.4 9.2 0.1 0.0 0.3 1.7 0.5 0.3 8.7 RHBDF1 "C16orf8, Dist1, EGFR-RS, FLJ2235, iRhom1" ENSG00000007384 "Rhomboid 5 homolog 1" Q96CC6 16 58059-76355 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 66.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077399 Uncertain Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA077399: " "unprognostic (2.62e-1)" "unprognostic (2.86e-2)" "unprognostic (4.76e-2)" "unprognostic (4.04e-2)" "unprognostic (1.51e-2)" "unprognostic (3.69e-2)" "unprognostic (5.60e-3)" "unprognostic (4.54e-3)" "unprognostic (4.51e-2)" "unprognostic (1.02e-1)" "unprognostic (7.81e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.81e-2)" "unprognostic (1.87e-1)" "unprognostic (8.36e-2)" "unprognostic (4.22e-2)" 41.9 11.5 14.5 6.0 14.4 0.5 44.3 13.5 19.5 65.1 13.3 38.2 7.5 38.1 13.0 47.0 36.4 22.1 51.7 14.3 13.5 24.7 13.2 58.5 5.5 14.5 14.4 55.6 23.4 8.9 13.3 27.5 13.9 61.2 7.1 2.5 38.3 16.5 34.1 46.1 24.8 10.5 14.0 19.3 28.5 8.0 14.7 1.2 33.4 16.9 5.5 44.6 61.4 13.5 10.8 17.3 9.7 22.5 37.2 45.7 31.8 29.1 53.8 20.1 19.1 23.5 36.9 0.6 11.8 31.1 10.2 33.6 4.8 19.6 3.4 0.5 5.3 0.4 18.8 6.6 41.4 0.3 18.3 38.3 20.3 51.9 8.6 35.5 31.4 0.1 4.1 0.4 32.2 60.6 0.1 3.5 8.8 22.7 14.5 0.3 11.5 0.9 22.7 11.0 0.3 2.4 8.4 31.8 18.7 11.9 49.1 3.8 32.6 31.5 21.9 24.8 8.1 0.2 0.7 0.3 22.0 0.6 50.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 14.4 13.5 19.5 14.3 13.5 14.5 14.4 13.9 14.0 14.7 13.5 10.5 19.2 6.2 9.1 0.3 6.8 9.9 15.2 5.2 0.8 17.8 13.5 9.9 22.8 15.8 9.2 66.7 19.0 0.3 21.9 0.0 21.4 1.1 3.8 9.9 9.2 0.0 0.0 1.7 8.0 16.3 20.6 15.8 11.2 0.0 8.7 8.2 3.0 2.2 0.0 0.6 9.8 18.3 0.6 5.1 1.1 19.6 0.4 16.0 5.6 0.0 6.9 0.0 16.6 0.7 28.4 13.6 13.9 0.2 25.8 2.1 2.3 5.3 4.9 13.1 10.8 22.3 0.3 1.9 6.6 5.5 30.6 0.8 16.4 3.8 17.9 RHOBTB3 KIAA0878 ENSG00000164292 "Rho related BTB domain containing 3" O94955 5 95713522-95824383 "Predicted intracellular proteins" Transport Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Leydig cells: 397.3;Peritubular cells: 314.8;Skeletal myocytes: 347.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 7.3" "Group enriched" "Detected in many" 4 "granulocytes: 7.3;T-cells: 1.9" "Cell line enhanced" "Detected in many" "EFO-21: 250.6;HaCaT: 332.7;SuSa: 315.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000265 Uncertain Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA000265: " "unprognostic (1.68e-1)" "unprognostic (9.60e-2)" "unprognostic (5.62e-2)" "unprognostic (1.31e-3)" "unprognostic (1.84e-1)" "unprognostic (3.39e-2)" "unprognostic (7.37e-2)" "unprognostic (4.28e-1)" "unprognostic (6.00e-3)" "unprognostic (9.29e-2)" "unprognostic (9.15e-2)" "unprognostic (3.64e-1)" "unprognostic (1.56e-3)" "unprognostic (7.01e-3)" "unprognostic (1.15e-1)" "unprognostic (3.23e-1)" "unprognostic (8.21e-2)" 79.8 38.3 58.8 11.9 81.2 8.1 23.8 59.1 64.2 27.7 12.1 22.5 14.8 13.1 27.0 17.0 16.5 19.7 33.7 55.6 47.8 28.3 21.7 16.9 6.8 81.5 56.4 83.0 111.1 55.6 13.2 54.0 52.1 28.8 20.8 29.0 41.9 20.6 29.8 13.2 16.6 20.6 50.6 11.3 22.6 21.4 64.5 8.3 19.9 32.7 2.3 25.5 13.4 67.4 53.7 20.4 51.1 55.1 188.4 108.5 0.5 91.0 86.4 34.7 54.0 96.5 9.6 0.2 250.6 45.8 88.5 332.7 27.7 6.6 59.4 2.2 36.6 18.3 185.8 28.9 148.6 4.3 25.5 176.6 4.8 52.0 0.9 147.6 27.0 15.5 74.7 13.4 139.3 14.8 5.8 14.9 19.7 33.4 33.4 8.2 100.3 6.5 29.1 35.6 90.3 118.9 71.8 31.0 85.7 315.9 23.6 26.3 44.5 46.1 195.7 31.1 35.8 13.5 28.3 2.7 14.8 1.1 76.8 0.1 0.6 7.3 1.9 0.3 0.7 0.5 1.4 1.6 0.1 0.1 1.8 0.4 0.4 0.3 1.0 0.8 0.8 0.6 58.8 81.2 59.1 64.2 55.6 47.8 81.5 56.4 52.1 50.6 64.5 67.4 23.4 176.3 13.3 229.9 5.4 10.8 65.8 25.9 13.6 68.3 81.2 44.1 79.4 44.3 49.8 141.6 20.9 62.2 15.7 21.4 60.7 69.7 11.4 55.3 118.6 15.7 92.0 32.6 35.2 111.0 139.7 201.3 3.1 76.8 100.1 178.3 14.3 77.3 33.3 6.7 57.3 66.9 14.2 23.0 11.6 22.1 397.3 20.4 42.7 30.0 3.7 270.3 71.1 117.6 64.8 40.7 70.1 314.8 7.1 53.8 19.9 3.1 33.7 35.9 32.9 347.6 99.2 4.6 8.8 10.1 27.4 115.2 9.8 177.2 84.5 102.2 RNF135 MGC13061 ENSG00000181481 "Ring finger protein 135" Q8IUD6 17 30970984-30999911 "Enzymes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 73.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 63.3" "Low region specificity" "Detected in all" "HPA021576, HPA052404" Approved Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA021576: AB_1856331, HPA052404: AB_2681817" "unprognostic (1.13e-1)" "unprognostic (1.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.33e-2)" "unprognostic (2.68e-2)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "unprognostic (4.60e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (7.51e-5)" "unprognostic (6.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-1)" "unprognostic (4.47e-1)" 20.9 12.9 11.1 13.5 12.5 11.6 18.6 11.2 14.2 16.0 15.1 17.5 13.6 13.3 16.5 22.4 15.7 9.6 8.5 10.4 11.3 21.6 8.6 15.5 13.9 13.9 13.2 12.6 13.5 16.8 5.6 18.1 12.4 14.0 18.0 2.3 15.2 15.2 7.4 26.2 13.9 13.7 12.8 25.8 11.9 5.1 16.4 7.9 15.8 10.1 12.6 14.8 17.3 13.8 12.7 25.6 1.5 25.4 34.0 28.5 22.7 9.7 14.9 9.4 8.4 0.0 9.4 11.5 14.8 19.0 17.0 17.0 13.2 12.1 7.8 10.0 5.6 4.8 8.1 0.0 24.3 12.8 10.7 27.7 63.3 10.1 33.5 16.1 15.8 0.0 0.0 34.9 15.6 17.0 0.1 13.5 10.5 25.7 14.4 27.9 0.0 39.2 13.6 18.2 9.8 0.5 14.9 5.9 14.9 16.6 39.4 20.2 13.3 0.0 3.5 15.6 11.5 0.4 1.3 7.3 16.5 22.1 13.3 25.3 61.6 31.3 12.8 57.3 7.2 28.4 6.8 6.8 46.4 28.4 3.7 6.2 54.0 13.9 70.2 17.1 10.1 29.2 11.1 12.5 11.2 14.2 10.4 11.3 13.9 13.2 12.4 12.8 16.4 13.8 14.1 3.2 5.9 7.8 14.1 9.3 13.4 16.8 22.2 0.1 13.1 15.0 4.0 7.2 7.8 11.0 0.0 47.5 10.5 23.4 29.4 9.9 0.4 14.5 12.8 13.2 4.9 11.2 0.8 18.6 37.1 13.2 5.6 12.4 1.3 14.1 25.4 2.7 51.1 0.0 1.0 12.0 8.2 73.9 8.4 1.6 16.8 35.5 16.0 26.2 45.3 3.9 19.6 9.0 0.7 11.9 13.1 15.4 9.0 22.2 27.5 49.3 10.4 0.6 26.3 8.2 14.2 0.7 4.0 24.1 14.6 43.6 7.5 10.6 14.6 11.2 RNF144A "hUIP4, KIAA0161, RNF144, UBCE7IP4" ENSG00000151692 "Ring finger protein 144A" P50876 2 6917412-7068286 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.6;Inhibitory neurons: 101.7;Oligodendrocyte precursor cells: 194.5;Oligodendrocytes: 330.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.1" "Group enriched" "Detected in many" 7 "granulocytes: 6.1;T-cells: 2.4" "Cell line enhanced" "Detected in many" "HEL: 39.7;HMC-1: 127.9;SH-SY5Y: 39.0;SK-MEL-30: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049939 Approved Supported Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA049939: AB_2680960" "unprognostic (1.78e-1)" "unprognostic (2.53e-3)" "unprognostic (8.37e-2)" "prognostic unfavorable (6.00e-4)" "unprognostic (6.57e-2)" "prognostic favorable (6.96e-4)" "unprognostic (7.04e-6)" "unprognostic (1.20e-1)" "unprognostic (2.03e-2)" "unprognostic (5.64e-1)" "unprognostic (9.11e-2)" "unprognostic (1.92e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (7.32e-5)" "unprognostic (1.30e-2)" "unprognostic (3.01e-1)" "unprognostic (1.82e-3)" 9.7 28.5 21.1 4.1 46.1 13.9 10.1 59.2 36.7 24.2 1.2 5.7 2.6 26.3 7.7 4.3 7.8 7.1 8.1 17.5 24.0 7.3 1.3 5.4 6.0 30.1 27.0 19.3 30.7 38.1 12.9 5.9 33.4 9.1 5.3 23.0 4.6 6.4 9.6 5.4 3.8 11.6 21.5 23.0 2.6 4.7 30.3 7.5 3.4 10.1 5.6 4.4 7.5 73.6 0.8 5.8 30.1 6.2 6.6 13.6 23.0 0.2 0.0 1.1 2.8 0.1 0.7 2.9 3.3 0.3 8.7 0.7 10.0 0.0 0.0 1.6 2.6 39.7 0.3 11.8 0.3 0.7 127.9 21.7 0.1 2.2 0.0 0.0 0.0 9.9 17.3 0.6 0.0 4.9 20.6 1.7 11.0 0.7 13.6 15.9 21.8 2.6 1.0 10.2 9.9 39.0 0.5 4.0 39.8 3.9 1.7 2.6 0.1 3.9 10.0 10.7 4.5 10.4 3.5 0.1 14.7 8.7 14.3 1.3 0.0 6.1 1.2 0.0 1.8 0.0 1.3 0.9 0.1 0.1 2.4 1.7 0.3 0.5 0.0 0.0 0.6 0.4 21.1 46.1 59.2 36.7 17.5 24.0 30.1 27.0 33.4 21.5 30.3 73.6 27.8 3.2 4.2 34.3 2.4 2.4 0.7 0.0 1.8 4.6 2.5 2.5 11.5 2.8 1.9 0.0 75.0 2.4 5.3 15.4 1.9 3.3 5.5 6.1 15.4 13.9 25.4 18.5 176.6 5.8 3.1 10.4 2.6 10.7 8.9 31.5 23.2 1.1 4.9 10.1 101.7 2.7 0.0 1.0 1.7 14.2 4.4 1.7 24.9 17.8 1.2 7.6 10.3 194.5 330.3 3.0 11.1 10.5 3.1 3.0 2.0 0.3 1.5 39.8 0.0 16.1 5.2 1.8 6.6 5.2 1.6 1.1 9.8 19.1 2.7 1.7 ROS1 "c-ros-1, MCF3, ROS" ENSG00000047936 "ROS proto-oncogene 1, receptor tyrosine kinase" P08922 6 117287353-117425942 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "epididymis: 58.6;lung: 31.7" "Cell type enriched" "Detected in some" 4 "Alveolar cells type 2: 78.5" "Cancer enriched" "Detected in some" 13 "lung cancer: 6.9" "Region enriched" "Detected in single" 4 "cerebral cortex: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "GAMG: 19.3;HSkMC: 10.1;hTCEpi: 21.7;LHCN-M2: 14.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049098, HPA072424" Uncertain Approved Vesicles NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049098: AB_2680628, HPA072424: AB_2686519" "unprognostic (8.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (7.57e-2)" "unprognostic (2.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-1)" "unprognostic (2.79e-2)" "unprognostic (1.00e-2)" "unprognostic (2.42e-1)" "unprognostic (5.20e-2)" "unprognostic (1.56e-12)" "unprognostic (1.09e-2)" "unprognostic (2.81e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.4 0.0 0.0 58.6 0.0 0.1 0.0 0.0 0.6 0.0 0.3 0.1 31.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.4 0.0 0.0 2.2 0.4 0.3 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 10.1 21.7 0.2 1.9 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 2.0 0.0 3.1 1.7 0.2 2.1 0.0 0.0 0.0 1.9 3.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.0 78.5 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.8 0.0 3.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.3 1.8 0.2 0.0 0.0 0.0 17.8 0.0 0.0 0.2 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.3 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 RRAS R-Ras ENSG00000126458 "RAS related" P10301 19 49635292-49640143 "Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 215.6;Pancreatic endocrine cells: 150.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 20.9;non-classical monocyte: 25.0" "Lineage enriched" "Detected in many" 7 "monocytes: 25.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010160, HPA060364, CAB069439" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB010160: AB_2180086, CAB069439: AB_1622637, HPA060364: AB_2684264" "unprognostic (9.23e-2)" "unprognostic (6.37e-2)" "unprognostic (1.50e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (8.54e-2)" "unprognostic (4.55e-3)" "prognostic unfavorable (5.28e-4)" "unprognostic (2.16e-2)" "unprognostic (7.58e-2)" "unprognostic (1.39e-3)" "unprognostic (2.30e-2)" "prognostic unfavorable (1.54e-9)" "unprognostic (6.13e-2)" "unprognostic (3.42e-2)" "unprognostic (7.14e-3)" "unprognostic (2.74e-2)" 167.4 59.1 36.6 43.6 36.8 5.2 129.6 35.7 49.4 162.6 33.9 241.7 40.3 187.0 24.9 58.4 168.3 47.1 201.9 34.4 39.0 99.2 40.9 168.9 37.2 40.1 36.2 79.9 31.1 14.6 28.5 63.5 38.1 147.8 23.6 4.9 52.8 160.2 51.9 52.9 89.5 84.2 37.2 100.2 117.7 35.3 39.7 15.0 83.8 49.8 20.1 173.3 139.4 35.4 82.1 99.4 12.5 25.3 212.7 236.1 3.8 105.8 148.7 50.6 65.9 13.7 134.2 5.1 54.0 156.8 73.2 53.6 7.3 108.5 20.7 33.4 5.5 9.7 32.3 8.4 197.2 0.6 20.3 167.3 95.1 63.9 50.7 213.5 130.4 3.7 6.4 39.1 91.3 32.4 0.5 9.3 2.5 69.5 80.0 7.7 30.4 15.3 111.4 16.3 0.2 11.6 41.5 36.8 6.7 32.4 52.5 7.8 187.3 147.3 58.9 26.0 30.9 28.7 13.0 1.3 153.1 6.3 47.4 0.0 5.4 0.1 0.6 20.9 0.5 2.0 1.6 0.5 3.7 0.4 1.7 0.4 0.0 0.6 25.0 1.0 0.7 2.2 36.6 36.8 35.7 49.4 34.4 39.0 40.1 36.2 38.1 37.2 39.7 35.4 215.6 38.5 7.9 2.3 6.2 29.6 54.4 126.4 11.4 1.7 44.4 57.4 61.1 27.1 48.7 51.5 2.1 4.9 7.4 60.8 9.8 65.9 0.9 12.5 90.0 75.4 10.2 3.6 1.2 55.7 41.2 76.6 16.3 29.9 10.2 2.3 79.2 7.1 31.5 5.0 0.6 22.2 30.5 28.3 23.2 6.1 60.3 32.1 26.6 8.4 32.9 59.1 4.1 0.0 0.8 150.4 33.0 76.0 6.0 62.0 53.3 10.7 14.5 2.5 78.9 35.2 135.9 1.8 5.4 11.9 19.2 7.1 9.4 9.3 17.8 54.4 RSPO1 "FLJ40906, RSPONDIN" ENSG00000169218 "R-spondin 1" Q2MKA7 1 37611350-37634892 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 28.9;endometrium 1: 41.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 7.7;Breast myoepithelial cells: 15.6;Fibroblasts: 5.4;Langerhans cells: 2.9" "Cancer enriched" "Detected in some" 13 "ovarian cancer: 11.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.2;THP-1: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046154, HPA062923" Uncertain Approved Vesicles "Secreted in female reproductive system" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA046154: AB_10964912, HPA062923: " "unprognostic (1.50e-2)" "unprognostic (1.97e-3)" "unprognostic (5.99e-3)" "unprognostic (2.22e-1)" "unprognostic (1.76e-1)" "unprognostic (3.75e-6)" "unprognostic (1.84e-2)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (2.08e-1)" "unprognostic (1.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.76e-2)" "unprognostic (3.21e-1)" "unprognostic (1.53e-2)" 11.3 0.1 0.0 0.8 0.1 0.1 7.9 0.1 0.1 28.9 0.0 1.8 1.1 41.4 2.2 3.1 20.0 2.7 0.7 0.1 0.0 0.8 0.1 4.0 1.9 0.1 0.1 2.1 0.5 0.1 0.1 0.4 0.1 6.7 0.5 0.1 1.3 1.8 0.0 6.6 3.3 13.1 0.0 0.8 4.0 0.2 0.1 0.0 0.0 0.5 3.0 1.5 19.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 7.7 15.6 0.3 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.9 0.1 0.9 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.4 0.1 0.3 0.0 0.0 0.1 RSU1 "FLJ31034, RSP-1" ENSG00000148484 "Ras suppressor protein 1" Q15404 10 16590611-16817463 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025927 Uncertain Approved Vesicles NA NA 33000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA025927: AB_10610420" "unprognostic (7.33e-2)" "unprognostic (1.42e-1)" "unprognostic (2.08e-1)" "unprognostic (4.89e-1)" "unprognostic (9.56e-3)" "unprognostic (2.91e-2)" "unprognostic (1.25e-3)" "unprognostic (1.99e-1)" "unprognostic (3.83e-2)" "unprognostic (3.72e-2)" "unprognostic (3.30e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (9.32e-5)" "unprognostic (1.11e-1)" "unprognostic (1.46e-1)" "unprognostic (2.48e-1)" "unprognostic (4.53e-2)" 35.6 14.2 8.8 22.0 8.9 27.9 25.4 8.8 10.1 21.2 10.1 27.8 12.0 30.3 19.9 27.7 19.2 19.7 25.1 8.7 10.1 19.4 16.7 27.7 22.3 10.5 9.4 21.8 21.2 14.1 3.9 23.2 9.8 17.9 23.8 9.9 14.5 27.0 15.8 15.9 13.7 41.8 8.6 20.4 15.6 5.5 10.4 18.1 18.7 13.8 22.3 24.0 18.0 9.6 27.3 18.6 15.0 88.5 78.4 80.3 18.3 66.3 28.2 45.1 48.6 17.3 25.0 27.0 10.5 91.2 24.1 23.9 18.3 34.7 48.3 40.6 14.6 85.2 11.1 16.7 34.5 13.1 47.8 40.0 36.0 43.3 13.7 40.9 47.8 27.8 14.0 18.2 61.6 17.6 30.5 23.5 15.7 39.6 10.5 19.6 20.3 18.4 44.0 10.0 5.9 11.6 33.1 21.6 33.6 26.8 7.6 34.4 58.8 38.4 13.3 48.5 34.6 15.9 20.6 23.3 51.0 37.1 16.9 33.0 20.9 22.8 24.7 26.0 28.0 16.6 28.1 26.7 34.7 17.9 20.5 25.8 14.6 31.3 25.5 25.9 36.0 48.5 8.8 8.9 8.8 10.1 8.7 10.1 10.5 9.4 9.8 8.6 10.4 9.6 111.1 35.3 24.5 26.4 29.9 36.7 30.3 74.0 12.0 1.7 22.5 36.2 41.2 27.1 48.3 42.3 2.1 131.9 41.6 57.0 68.4 72.1 80.5 20.7 47.2 69.6 7.2 74.7 52.8 119.2 83.0 52.8 28.5 24.8 34.2 20.5 64.2 32.7 121.7 3.3 34.7 19.0 52.9 61.1 80.7 163.3 39.4 106.2 60.5 52.5 92.3 5.8 66.9 45.8 51.7 81.2 16.8 68.4 36.7 17.4 14.9 58.3 48.8 17.9 65.7 32.4 136.1 3.9 22.6 34.1 42.8 96.2 46.8 35.9 27.2 24.9 RUNDC3A "RAP2IP, RPIP8" ENSG00000108309 "RUN domain containing 3A" Q59EK9 17 44308413-44318670 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 208.4;pituitary gland: 98.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 55.4;Early spermatids: 24.4;Enteroendocrine cells: 39.0;Excitatory neurons: 46.1;Horizontal cells: 32.0;Inhibitory neurons: 30.4;Late spermatids: 83.4" "Group enriched" "Detected in many" 5 "glioma: 8.6;pancreatic cancer: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "SCLC-21H: 62.5;SH-SY5Y: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023548, HPA070733" Enhanced Supported Enhanced Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA023548: AB_1856069, HPA070733: AB_2732162" "unprognostic (3.66e-2)" "unprognostic (3.77e-2)" "unprognostic (3.50e-3)" "unprognostic (1.58e-3)" "unprognostic (3.04e-1)" "unprognostic (2.02e-1)" "unprognostic (3.87e-3)" "unprognostic (2.29e-1)" "unprognostic (4.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.42e-3)" "unprognostic (1.34e-1)" "unprognostic (8.87e-3)" "unprognostic (1.07e-2)" "unprognostic (5.17e-2)" "unprognostic (9.39e-2)" "unprognostic (1.84e-1)" 0.3 14.3 149.2 0.4 159.5 2.3 0.3 93.0 208.4 0.2 45.6 3.4 1.2 0.5 0.2 0.8 0.2 0.3 1.8 169.4 105.3 1.8 0.2 0.4 0.2 108.0 106.4 0.8 3.8 3.1 98.3 1.5 108.5 0.8 0.6 31.2 0.3 0.3 0.1 7.9 1.3 0.5 79.2 1.6 2.3 15.2 109.4 0.4 1.4 0.3 0.1 0.2 0.7 135.7 0.0 0.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 4.3 0.0 1.4 0.3 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 8.0 0.0 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 0.9 0.2 0.0 0.5 0.3 0.3 0.1 0.1 1.1 0.3 0.1 62.5 40.3 0.3 0.0 0.3 0.1 0.5 0.8 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 149.2 159.5 93.0 208.4 169.4 105.3 108.0 106.4 108.5 79.2 109.4 135.7 0.1 0.0 0.6 17.3 0.0 0.3 0.3 0.0 0.0 55.4 0.2 0.3 1.1 0.0 0.0 0.0 6.2 0.0 0.0 0.0 3.9 1.3 24.4 0.2 0.3 0.2 39.0 18.7 46.1 3.1 0.0 1.0 0.0 0.2 0.0 0.5 0.4 0.0 0.2 32.0 30.4 0.5 4.1 0.3 0.5 83.4 1.5 0.3 0.0 4.7 0.1 6.5 1.0 16.1 12.5 1.0 1.2 3.4 0.0 0.4 0.0 0.8 0.0 16.8 0.0 0.8 0.5 1.4 1.3 0.0 0.4 0.1 0.1 3.0 0.1 0.3 RWDD2A "dJ747H23.2, MGC13523, RWDD2" ENSG00000013392 "RWD domain containing 2A" Q9UIY3 6 83193357-83198935 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 52.3;Spermatocytes: 65.2" "Cancer enhanced" "Detected in all" "prostate cancer: 11.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030105, HPA030106, HPA030107" Uncertain Approved Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA030105: AB_10599826, HPA030106: AB_10600896, HPA030107: AB_10601009" "unprognostic (2.51e-3)" "unprognostic (1.25e-1)" "unprognostic (2.48e-2)" "unprognostic (1.33e-1)" "unprognostic (1.19e-3)" "unprognostic (3.99e-2)" "unprognostic (1.01e-1)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "prognostic favorable (3.82e-5)" "prognostic favorable (1.38e-4)" "unprognostic (1.26e-1)" "unprognostic (2.73e-1)" "unprognostic (1.91e-2)" "unprognostic (2.57e-2)" "unprognostic (1.85e-3)" "unprognostic (2.59e-2)" 2.9 6.9 7.1 2.1 7.0 0.5 3.2 6.1 8.1 3.4 6.3 2.9 2.5 3.3 9.4 1.7 3.8 4.6 4.4 6.9 7.9 4.5 5.9 2.8 2.5 5.6 6.0 4.0 9.6 4.0 5.6 2.5 5.9 11.5 2.5 4.7 6.0 4.7 2.3 1.9 2.7 3.2 5.7 2.9 3.9 8.9 8.4 1.8 6.2 4.0 2.6 2.6 1.8 6.1 2.1 1.9 4.4 8.3 5.2 3.7 3.0 4.8 10.1 3.5 4.2 2.8 1.1 1.6 3.8 5.8 8.0 2.1 3.7 2.8 5.4 2.0 3.8 1.9 3.0 6.2 8.0 0.5 1.5 4.9 4.6 4.4 9.2 11.5 6.6 4.5 3.1 2.8 4.3 3.1 0.7 1.5 1.5 1.9 1.9 2.4 9.1 1.0 7.4 2.4 1.5 5.3 2.9 4.5 4.4 6.3 2.8 2.9 7.1 2.4 1.5 3.5 2.1 6.2 2.7 0.9 2.8 0.8 2.9 0.3 0.9 0.0 1.2 0.8 1.8 1.9 1.7 1.7 1.0 1.0 2.2 2.1 0.3 0.4 2.2 3.5 2.2 1.0 7.1 7.0 6.1 8.1 6.9 7.9 5.6 6.0 5.9 5.7 8.4 6.1 2.4 0.0 6.7 9.8 4.2 3.7 3.6 5.3 3.4 5.6 3.7 3.2 5.4 2.8 3.3 1.8 0.0 7.7 3.9 2.4 5.9 8.9 52.3 4.8 4.5 3.5 5.4 0.4 10.8 9.1 3.3 6.5 3.6 4.0 0.0 7.0 5.0 6.8 5.0 1.7 11.2 6.1 8.2 1.6 2.5 14.8 9.0 2.2 8.8 3.7 3.8 11.0 0.0 13.6 4.5 5.8 2.5 6.0 11.2 8.7 4.1 13.3 4.9 5.0 6.6 7.0 5.2 65.2 10.5 1.2 2.4 5.7 2.9 6.3 3.4 2.8 RYR3 ENSG00000198838 "Ryanodine receptor 3" Q15413 15 33310962-33866121 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.7;choroid plexus: 33.3;skeletal muscle: 24.2;tongue: 44.2" "Cell type enriched" "Detected in many" 4 "Astrocytes: 788.8" "Cancer enriched" "Detected in single" 4 "glioma: 1.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 1.9" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cell line enhanced" "Detected in some" "A549: 4.4;RH-30: 6.5;RPTEC TERT1: 3.1;SuSa: 2.8" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 23.4" HPA062004 Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 70: Brain - Nervous system development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA062004: AB_2797267" "unprognostic (5.85e-2)" "unprognostic (1.57e-1)" "unprognostic (5.30e-2)" "unprognostic (1.35e-1)" "unprognostic (1.26e-2)" "unprognostic (8.03e-4)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (7.85e-2)" "unprognostic (7.10e-2)" "unprognostic (8.25e-3)" "unprognostic (2.36e-1)" "unprognostic (2.48e-2)" "unprognostic (1.86e-2)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (1.91e-1)" 1.7 0.7 35.2 0.2 43.7 1.4 2.0 33.5 39.7 4.2 33.3 10.1 0.4 7.2 0.1 1.2 5.4 0.5 0.2 35.6 29.3 2.0 0.0 0.3 0.1 35.5 30.2 0.9 0.1 6.1 1.3 0.1 33.5 1.4 1.3 2.2 0.5 2.0 24.2 1.0 1.8 4.4 24.3 0.5 2.1 0.5 37.1 0.6 0.3 44.2 0.4 4.0 2.8 28.8 0.2 4.4 0.9 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 1.1 0.1 0.2 0.4 0.0 1.4 0.1 0.0 0.0 0.0 0.2 0.1 0.9 0.1 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 1.6 0.0 0.2 0.1 0.1 0.7 0.2 0.1 0.3 6.5 0.1 3.1 0.3 0.1 0.3 0.4 0.0 0.1 2.8 0.0 0.2 0.5 0.1 0.1 0.0 0.4 0.2 0.9 0.4 0.3 1.4 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.2 43.7 33.5 39.7 35.6 29.3 35.5 30.2 33.5 24.3 37.1 28.8 2.9 0.0 1.1 788.8 0.2 0.4 0.0 0.0 0.0 8.0 0.2 2.5 2.2 0.0 0.6 0.0 0.0 0.6 0.5 0.0 0.0 0.0 15.5 7.7 1.4 1.8 0.0 8.4 162.5 0.0 0.7 0.6 0.0 8.0 14.0 0.2 0.0 0.0 1.0 69.0 115.2 0.0 0.0 0.0 1.0 41.9 0.3 0.3 0.0 36.5 0.6 0.3 0.0 22.1 5.9 0.0 0.0 0.0 0.1 0.0 0.0 0.3 5.9 0.8 0.0 51.3 0.4 0.1 1.5 0.0 0.6 0.1 0.4 2.5 0.0 0.0 S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 236.1;Endothelial cells: 122.3;Hepatic stellate cells: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1248.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 73.0;HUVEC TERT2: 198.9;TIME: 113.3;U-251 MG: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" 114.7 14.4 58.8 29.8 62.7 18.5 91.9 59.8 59.0 18.5 27.8 19.5 9.4 24.7 3.9 26.8 22.9 28.0 71.8 51.3 65.1 18.0 31.3 78.3 46.3 65.2 73.0 8.2 20.3 23.3 8.7 48.1 61.3 13.7 10.1 14.6 15.0 7.8 27.9 17.9 22.3 31.2 57.6 63.1 17.1 2.6 76.5 21.4 35.9 51.5 26.9 34.3 19.2 52.6 15.6 0.2 14.2 0.0 1.4 32.7 0.1 73.0 13.5 47.9 16.6 0.1 0.7 0.0 17.8 25.2 0.4 0.0 1.8 0.8 27.0 6.1 1.2 6.8 0.3 0.0 6.6 0.0 3.5 45.0 0.3 0.1 3.7 1.7 198.9 5.8 0.2 14.4 13.5 0.0 20.6 0.0 3.9 0.4 4.8 0.0 13.4 0.5 0.1 0.0 0.0 0.1 0.7 0.0 0.2 0.9 0.0 0.2 113.3 6.8 2.9 2.0 147.1 1.3 0.0 1.0 0.7 0.0 0.4 1248.4 2.2 55.4 589.4 2.1 441.5 294.7 502.6 492.1 2.6 346.9 383.3 396.3 15.4 397.5 3.4 3.1 329.4 438.7 58.8 62.7 59.8 59.0 51.3 65.1 65.2 73.0 61.3 57.6 76.5 52.6 236.1 0.0 8.9 37.9 36.0 7.6 0.2 0.0 2.2 0.4 1.1 1.1 23.8 2.8 1.3 0.0 0.0 5.9 25.0 0.0 0.0 0.0 0.0 1.1 1.0 122.3 0.0 0.4 0.1 0.0 0.3 11.7 0.5 1.8 7.6 9.7 114.2 8.9 9.9 0.0 0.3 0.0 0.0 6.5 5.7 0.0 0.9 3.0 5.4 13.1 9.9 31.1 40.2 0.5 0.2 0.0 0.0 0.0 18.2 0.5 0.0 0.1 0.0 1.4 0.0 3.6 4.8 0.7 0.7 0.6 5.1 2.6 29.9 1.8 0.1 0.4 SAMD5 dJ875H10.1 ENSG00000203727 "Sterile alpha motif domain containing 5" Q5TGI4 6 147508690-147737547 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Bipolar cells: 96.0;Inhibitory neurons: 276.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 16.6;Hep G2: 65.6;K-562: 44.7;RH-30: 29.0;WM-115: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067811 Uncertain Supported Vesicles No No "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA067811: AB_2685901" "unprognostic (4.16e-2)" "unprognostic (4.52e-2)" "unprognostic (9.65e-3)" "unprognostic (1.41e-2)" "unprognostic (1.82e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (2.31e-1)" "unprognostic (1.54e-1)" "unprognostic (1.61e-2)" "unprognostic (8.55e-3)" "unprognostic (3.09e-2)" "unprognostic (5.40e-3)" "unprognostic (1.72e-1)" "unprognostic (4.51e-2)" "unprognostic (9.82e-3)" "unprognostic (1.50e-1)" 0.6 1.8 2.8 1.3 5.6 0.1 4.1 1.0 2.6 1.4 0.1 6.0 3.0 4.2 0.8 8.9 0.9 2.2 1.2 2.7 4.0 7.4 7.5 3.4 0.3 8.7 4.1 0.4 1.3 5.7 3.8 12.2 9.1 1.4 8.1 8.9 2.3 2.4 0.2 1.9 4.4 3.1 0.0 1.4 4.5 7.6 7.2 0.1 2.1 0.1 0.7 1.5 1.9 0.8 11.2 1.4 1.4 2.0 0.0 0.0 0.1 3.6 1.3 0.3 0.2 16.6 0.1 0.6 3.6 0.0 0.6 0.1 0.3 2.5 0.4 0.0 2.0 0.8 1.5 65.6 0.2 0.0 1.3 0.0 0.1 0.3 0.1 0.0 6.8 0.0 44.7 0.6 4.8 0.1 0.0 0.0 0.1 8.4 2.8 0.0 29.0 6.5 0.1 2.3 0.5 0.1 0.9 0.2 2.8 0.3 0.0 0.0 4.9 0.5 1.5 0.5 1.3 0.1 1.1 0.0 0.1 0.1 20.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 5.6 1.0 2.6 2.7 4.0 8.7 4.1 9.1 0.0 7.2 0.8 1.7 3.2 5.9 1.3 1.0 1.8 5.6 0.5 2.2 96.0 2.9 23.5 2.6 0.0 0.0 18.4 2.1 0.2 0.0 5.4 9.8 2.2 0.5 1.1 10.7 11.1 16.9 0.0 15.7 0.2 0.3 6.9 19.4 1.8 0.0 7.0 6.1 28.1 0.8 0.0 276.9 11.6 0.0 1.0 1.4 1.3 0.3 0.7 0.0 45.0 0.0 9.2 0.0 5.5 0.9 0.6 3.4 3.4 0.1 3.0 5.2 19.7 0.0 4.0 0.0 3.1 2.0 0.5 0.2 36.4 1.6 0.3 0.5 3.6 25.7 4.2 SAYSD1 "C6orf64, FLJ11101" ENSG00000112167 "SAYSVFN motif domain containing 1" Q9NPB0 6 39104063-39115186 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 55.5" "Group enriched" "Detected in many" 4 "Early spermatids: 136.1;Late spermatids: 63.2;Spermatocytes: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007959 Approved Supported Vesicles NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 23: Testis - Cell cycle regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA007959: AB_1078359" "unprognostic (2.65e-1)" "unprognostic (1.49e-2)" "unprognostic (2.03e-2)" "unprognostic (2.58e-1)" "unprognostic (3.70e-1)" "unprognostic (2.56e-1)" "unprognostic (9.90e-3)" "unprognostic (1.96e-2)" "unprognostic (6.50e-2)" "unprognostic (1.82e-3)" "unprognostic (5.08e-2)" "unprognostic (9.90e-2)" "unprognostic (2.54e-2)" "unprognostic (1.79e-1)" "unprognostic (9.78e-3)" "unprognostic (2.27e-1)" "unprognostic (2.00e-3)" 8.8 7.9 7.8 6.5 8.4 7.6 10.5 8.3 10.3 8.6 8.0 8.7 9.9 8.4 11.1 7.5 8.6 6.9 8.3 8.2 8.3 9.6 10.1 7.0 10.3 8.0 8.1 8.8 11.1 7.7 6.3 6.7 8.1 9.2 7.8 6.8 12.6 8.2 7.0 7.4 9.4 6.8 8.1 7.5 7.8 55.5 8.1 17.0 8.7 7.0 9.4 7.2 6.9 9.6 14.8 9.4 8.3 9.9 13.4 17.7 8.6 6.7 7.3 7.9 8.3 13.6 10.2 13.4 9.4 8.8 11.2 9.9 7.3 6.3 8.3 8.5 13.2 8.8 5.5 11.9 10.9 10.1 12.7 12.3 15.4 3.1 7.8 5.6 7.4 19.9 15.1 7.9 9.0 20.4 16.1 16.6 7.2 9.7 4.8 2.3 10.1 5.4 16.7 10.3 23.3 9.4 11.6 10.0 10.9 6.6 16.4 13.1 9.7 10.4 7.5 3.2 8.8 0.2 4.3 16.2 6.0 14.4 7.8 10.6 10.8 24.9 14.0 15.1 16.0 16.4 15.2 12.8 11.4 18.5 21.0 17.9 5.2 15.8 15.8 9.0 22.2 12.1 7.8 8.4 8.3 10.3 8.2 8.3 8.0 8.1 8.1 8.1 8.1 9.6 19.3 3.2 6.0 4.6 11.4 15.4 13.2 29.1 8.6 6.4 26.4 21.8 18.8 21.5 17.0 18.4 8.4 33.1 8.3 10.5 17.6 22.9 136.1 22.8 14.0 11.2 8.4 13.5 3.2 21.8 32.7 16.8 4.6 19.0 8.2 13.8 6.4 23.3 26.8 6.7 4.2 16.5 2.0 13.9 15.7 63.2 20.5 13.2 12.4 0.0 11.9 15.5 12.3 9.0 6.3 15.9 9.7 19.2 5.3 22.6 21.8 28.3 19.2 4.1 6.6 13.1 17.3 223.6 14.5 11.6 16.6 12.3 12.8 10.2 20.1 14.9 SBSN "HLAR698, UNQ698" ENSG00000189001 Suprabasin Q6UWP8 19 35523367-35528351 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1056.2;skin 1: 2444.7;vagina: 756.5" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 1017.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 355.2;melanoma: 153.1" "Group enriched" "Detected in some" 5 "basal ganglia: 3.9;cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.2;ASC TERT1: 107.5;HSkMC: 146.1;U-2197: 51.6;U-87 MG: 119.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA062568, HPA067734" Enhanced Approved Vesicles "Secreted - unknown location" NA NA 89000000 "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA062568: AB_2684794, HPA067734: AB_2685894" "unprognostic (1.10e-1)" "unprognostic (1.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "unprognostic (1.83e-2)" "unprognostic (1.23e-3)" "unprognostic (3.45e-3)" "unprognostic (2.56e-1)" "unprognostic (4.83e-4)" "unprognostic (4.31e-4)" "unprognostic (6.97e-2)" "unprognostic (9.08e-14)" "unprognostic (6.37e-2)" "unprognostic (6.51e-3)" "unprognostic (2.09e-1)" "unprognostic (1.36e-3)" 2.9 0.6 0.5 0.1 3.9 0.7 94.3 0.4 1.3 465.7 0.3 1.0 0.0 0.5 0.0 1056.2 0.2 0.3 1.4 0.5 0.4 0.4 1.7 0.9 0.0 0.5 0.4 0.7 1.5 0.0 0.9 0.3 0.5 0.5 0.0 0.0 351.8 0.0 13.1 2444.7 0.7 0.2 0.4 0.5 1.1 1.0 0.5 6.5 0.7 0.0 168.9 1.1 756.5 0.4 0.1 0.1 0.0 0.1 62.2 107.5 0.1 5.1 7.2 2.4 0.9 0.0 0.1 0.1 1.2 4.8 1.7 0.3 0.0 1.8 1.0 0.1 0.2 0.0 0.1 0.0 0.6 0.0 0.1 146.1 8.2 30.0 7.1 2.1 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 1.4 0.3 0.2 0.0 0.4 18.4 3.8 51.6 1.4 0.5 0.3 0.0 119.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.9 0.4 1.3 0.5 0.4 0.5 0.4 0.5 0.4 0.5 0.4 0.0 0.0 0.0 0.0 0.0 89.3 0.1 0.6 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1.4 0.8 1.8 0.0 0.0 0.2 0.6 0.2 3.1 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 25.2 4.0 0.0 0.2 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.1 1.0 0.2 0.2 13.4 1017.6 0.3 0.7 0.0 0.0 0.4 SBSPON "C8orf84, RPESP" ENSG00000164764 "Somatomedin B and thrombospondin type 1 domain containing" Q8IVN8 8 73064543-73124088 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 36.5;Collecting duct cells: 42.3;Muller glia cells: 48.5;Peritubular cells: 26.7;Smooth muscle cells: 28.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "medulla oblongata: 7.5;pons: 6.3;spinal cord: 7.7;white matter: 16.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ: 9.5;RPTEC TERT1: 16.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA029595 Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 40000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA029595: AB_10600763" "prognostic favorable (7.18e-4)" "unprognostic (5.08e-3)" "unprognostic (3.24e-1)" "unprognostic (4.41e-2)" "unprognostic (1.75e-1)" "unprognostic (2.31e-1)" "unprognostic (2.78e-2)" "unprognostic (8.65e-2)" "unprognostic (2.92e-1)" "unprognostic (1.46e-1)" "unprognostic (9.54e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (6.14e-2)" "unprognostic (3.54e-1)" "unprognostic (2.12e-2)" "unprognostic (6.25e-2)" 6.4 3.0 0.4 1.4 0.5 0.3 3.4 1.2 0.6 5.2 0.6 4.7 0.9 4.4 4.5 9.5 8.2 1.3 2.3 0.8 0.8 8.3 0.6 3.9 1.5 7.5 0.9 3.3 1.2 0.1 1.6 9.4 6.3 15.1 1.1 9.0 4.6 10.8 0.6 1.9 2.5 8.9 7.7 1.1 9.6 2.6 0.4 0.2 2.5 1.4 0.2 17.9 4.7 16.7 0.2 0.2 0.4 0.5 0.0 0.0 1.3 9.5 0.0 0.0 0.0 0.1 0.2 0.4 0.5 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.4 0.3 0.4 0.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.3 0.0 0.0 0.4 0.3 0.9 0.5 0.2 0.2 0.1 0.0 16.9 0.1 0.5 0.5 1.0 0.4 0.1 3.1 0.2 0.1 0.5 0.1 1.5 0.2 0.2 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.5 1.2 0.6 0.8 0.8 7.5 0.9 6.3 7.7 0.4 16.7 0.6 9.6 0.0 1.0 0.2 1.3 6.9 0.0 36.5 2.4 5.8 11.6 3.8 4.3 0.0 42.3 2.1 0.2 1.0 0.5 1.9 1.3 10.3 7.2 1.4 1.7 0.0 0.0 0.5 0.0 0.4 13.2 10.7 14.9 0.0 0.2 1.4 0.2 0.4 0.0 0.4 0.2 0.0 0.0 0.4 3.2 12.2 0.4 3.6 0.0 0.0 48.5 0.0 1.0 0.2 0.6 0.0 26.7 0.0 1.8 0.0 3.6 0.0 2.2 6.6 0.9 28.7 11.4 4.4 0.6 1.3 0.4 0.5 0.2 0.1 0.5 SCAMP3 C1orf3 ENSG00000116521 "Secretory carrier membrane protein 3" O14828 1 155255979-155262430 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071167 Supported Vesicles NA NA 75000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA071167: AB_2686352" "unprognostic (4.31e-2)" "unprognostic (1.30e-2)" "unprognostic (1.07e-2)" "unprognostic (2.17e-2)" "unprognostic (5.33e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (2.92e-5)" "unprognostic (8.78e-2)" "unprognostic (1.40e-1)" "unprognostic (1.06e-1)" "unprognostic (2.65e-1)" "unprognostic (3.74e-2)" "unprognostic (8.46e-3)" "unprognostic (1.60e-1)" "unprognostic (4.79e-1)" "unprognostic (1.07e-1)" "unprognostic (7.18e-2)" 45.1 69.6 4.6 7.1 6.8 7.9 43.5 6.3 8.2 38.1 4.5 37.4 7.7 35.2 0.2 49.9 31.9 5.0 65.0 5.0 4.5 49.0 48.4 40.9 12.1 6.3 5.2 34.9 51.9 4.7 33.8 7.3 5.6 37.0 2.4 1.1 49.3 6.1 90.9 56.4 38.4 3.5 6.4 46.5 47.0 28.3 5.4 8.3 38.6 3.2 7.2 39.5 38.6 8.2 19.7 30.2 11.2 8.8 8.3 6.8 14.5 21.6 20.7 26.3 19.4 30.0 15.7 45.1 49.3 10.9 15.7 20.5 9.0 18.7 1.8 29.8 68.3 25.7 11.7 8.5 26.1 30.5 17.4 9.7 20.9 21.2 10.3 3.3 18.9 49.3 38.2 18.3 11.6 38.3 50.5 14.6 16.5 27.9 59.4 43.1 9.1 67.5 4.8 13.1 8.3 20.0 26.2 8.0 39.1 3.4 32.1 13.7 29.0 20.9 17.5 29.3 29.6 43.3 84.8 52.9 16.7 41.1 15.2 41.0 47.5 52.8 94.4 51.7 86.8 98.8 91.3 91.1 58.1 100.3 83.3 86.6 6.7 76.0 71.4 102.4 101.0 100.9 4.6 6.8 6.3 8.2 5.0 4.5 6.3 5.2 5.6 6.4 5.4 8.2 23.0 16.0 37.1 12.4 33.8 38.2 23.8 57.3 54.1 18.5 27.3 19.3 39.1 30.0 43.7 33.1 4.2 86.4 27.2 19.0 9.8 49.0 1.7 16.3 20.8 33.1 30.1 14.5 9.9 69.4 55.1 27.1 27.0 26.3 25.3 16.6 32.9 37.9 57.3 18.5 11.9 24.3 42.7 21.3 26.7 5.3 17.1 23.0 24.9 7.5 41.3 20.2 30.9 9.5 17.4 48.5 19.9 18.8 56.1 24.7 36.8 24.4 22.6 10.9 13.1 16.7 27.3 20.0 5.5 46.7 40.1 71.3 33.4 20.5 30.1 22.5 SCCPDH "CGI-49, NET11" ENSG00000143653 "Saccharopine dehydrogenase (putative)" Q8NBX0 1 246724409-246768137 "Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 159.5" "Group enriched" "Detected in all" 4 "Early spermatids: 1380.7;Spermatocytes: 822.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 20 "basophil: 872.9" "Lineage enriched" "Detected in all" 26 "granulocytes: 872.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050775, HPA076030" Enhanced Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA050775: AB_2681231, HPA076030: " "unprognostic (4.25e-1)" "unprognostic (3.11e-1)" "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (2.83e-2)" "unprognostic (6.43e-2)" "unprognostic (1.25e-1)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (5.51e-2)" "unprognostic (1.93e-1)" "unprognostic (3.60e-1)" "unprognostic (2.70e-2)" "unprognostic (9.63e-2)" "unprognostic (1.13e-1)" "unprognostic (2.24e-1)" "unprognostic (3.93e-2)" 26.6 53.7 35.1 14.4 45.5 35.7 23.6 51.5 43.2 22.6 40.8 27.2 34.4 26.2 17.6 9.3 31.6 21.6 32.8 35.3 45.4 49.8 158.2 21.0 13.5 64.0 45.2 22.4 18.8 36.5 24.3 23.8 64.3 39.4 26.8 31.7 15.3 26.0 60.7 24.1 34.6 24.0 57.0 11.5 28.0 159.5 47.3 20.1 33.5 54.7 10.6 81.5 12.0 86.8 55.3 53.2 37.7 22.8 44.5 55.7 0.5 42.3 58.8 70.1 58.3 32.7 150.6 29.3 53.8 49.0 38.9 17.7 32.4 12.6 71.6 40.8 11.9 49.6 46.9 65.9 41.6 97.1 40.7 37.6 5.9 47.4 4.8 65.7 76.4 60.0 62.9 0.1 70.9 13.5 101.6 122.6 56.5 29.6 41.7 83.8 48.5 0.3 216.6 128.2 42.7 48.0 57.3 2.5 39.0 20.2 42.1 99.6 49.8 32.1 28.5 78.7 110.5 138.0 51.1 17.4 54.7 130.2 43.3 872.9 24.3 44.1 18.1 22.2 22.4 11.2 5.4 15.7 10.7 9.4 7.1 22.0 6.4 34.1 15.4 18.2 4.0 17.1 35.1 45.5 51.5 43.2 35.3 45.4 64.0 45.2 64.3 57.0 47.3 86.8 25.0 6.4 11.5 25.8 8.0 30.1 40.6 54.6 1.8 31.2 42.4 17.5 38.0 55.8 40.5 152.6 18.8 41.4 14.6 42.4 31.3 67.2 1380.7 72.7 39.4 23.6 44.9 54.7 23.7 69.0 17.4 35.7 32.6 111.9 57.2 49.2 22.5 187.8 89.4 6.7 20.5 27.4 52.9 45.7 13.7 245.6 47.5 29.7 48.0 10.3 20.3 67.4 18.6 27.2 37.3 75.2 27.8 47.4 8.3 49.2 138.4 69.7 79.4 39.2 19.7 36.7 39.4 822.3 76.2 5.6 68.5 84.6 17.0 42.8 55.0 201.9 SCG3 "FLJ90833, SgIII" ENSG00000104112 "Secretogranin III" Q8WXD2 15 51681492-51721026 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 133.5;choroid plexus: 40.1;pituitary gland: 39.4;retina: 56.8" "Group enriched" "Detected in many" 4 "Astrocytes: 79.3;Bipolar cells: 120.4;Cone photoreceptor cells: 102.2;Enteroendocrine cells: 148.4;Excitatory neurons: 46.2;Horizontal cells: 148.0;Inhibitory neurons: 64.0;Ionocytes: 38.7;Oligodendrocyte precursor cells: 63.3;Rod photoreceptor cells: 93.3" "Group enriched" "Detected in many" 7 "glioma: 41.0;pancreatic cancer: 15.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "NTERA-2: 50.5;SCLC-21H: 121.2;SH-SY5Y: 57.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006880, CAB033274, HPA053715" Enhanced Supported Supported Vesicles "Secreted in brain" NA NA 3100000 "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" Vesicles "CAB033274: AB_2302033, HPA006880: AB_1079898, HPA053715: AB_2682239" "unprognostic (1.38e-2)" "unprognostic (2.42e-1)" "unprognostic (1.40e-1)" "unprognostic (5.24e-5)" "unprognostic (1.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.74e-1)" "unprognostic (9.93e-2)" "unprognostic (1.40e-1)" "unprognostic (2.46e-1)" "unprognostic (1.71e-2)" "unprognostic (8.17e-2)" "unprognostic (1.03e-1)" "unprognostic (2.78e-1)" "unprognostic (2.78e-1)" "unprognostic (8.88e-2)" "unprognostic (1.27e-1)" 0.5 16.7 71.0 1.1 87.0 0.6 0.5 85.8 133.5 0.1 40.1 1.8 2.3 0.2 0.3 0.3 0.3 0.2 0.2 88.2 112.7 0.2 0.2 0.6 0.4 68.7 75.8 0.1 15.6 0.2 39.4 0.1 68.9 0.3 2.0 56.8 0.2 0.0 0.1 0.6 2.0 0.5 71.9 0.2 9.9 2.6 79.8 0.5 1.0 0.0 0.2 0.2 0.2 71.6 0.2 0.1 4.8 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.2 0.2 0.3 0.5 0.0 0.6 0.4 0.1 0.0 0.1 0.1 0.5 0.1 0.3 0.1 0.0 0.3 3.0 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.2 0.8 0.0 0.3 0.1 0.1 50.5 0.1 0.2 0.3 0.1 0.4 0.0 0.5 121.2 57.5 0.2 0.4 0.2 15.5 0.1 3.8 0.1 0.3 0.7 0.2 0.2 0.4 0.2 0.4 0.7 0.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 71.0 87.0 85.8 133.5 88.2 112.7 68.7 75.8 68.9 71.9 79.8 71.6 0.2 0.0 0.0 79.3 0.0 0.3 0.0 0.3 0.0 120.4 0.0 0.1 0.2 0.0 0.1 0.0 102.2 0.0 0.0 0.2 1.9 0.4 20.0 0.0 0.0 4.3 148.4 0.0 46.2 1.0 0.1 4.1 0.0 0.0 0.0 0.0 1.8 0.0 0.4 148.0 64.0 3.4 38.7 0.0 0.3 11.3 0.0 0.1 1.8 7.5 6.7 19.2 0.0 63.3 8.9 5.3 0.0 0.4 0.0 0.4 0.1 0.0 0.8 93.3 0.0 0.4 0.2 13.8 5.8 0.0 0.0 0.0 0.0 0.2 0.3 0.3 SCGB2A1 "LPHC, MGB2, MGC71973, UGB3" ENSG00000124939 "Secretoglobin family 2A member 1" O75556 11 62208673-62213943 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 2021.0;epididymis: 1372.0" "Group enriched" "Detected in many" 6 "Endometrial ciliated cells: 2506.4;Glandular and luminal cells: 2597.0" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 971.9" "Region enhanced" "Detected in some" "medulla oblongata: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "EFO-21: 8.6" HPA034584 Enhanced Approved Vesicles "Secreted in other tissues" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Vesicles "HPA034584: AB_10602221" "unprognostic (7.73e-2)" "unprognostic (3.77e-1)" "prognostic favorable (1.22e-4)" "prognostic favorable (1.54e-8)" "unprognostic (2.98e-2)" "unprognostic (1.86e-2)" "unprognostic (3.39e-1)" "unprognostic (1.95e-1)" "unprognostic (2.69e-1)" "unprognostic (6.87e-3)" "prognostic favorable (6.36e-4)" "unprognostic (5.67e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" "unprognostic (3.35e-1)" 0.2 0.0 0.0 0.2 0.0 0.0 57.8 0.0 0.0 2021.0 0.1 12.7 1.3 118.8 1372.0 4.2 238.4 13.4 0.2 0.1 0.4 1.9 0.1 2.4 0.0 3.5 1.4 0.7 17.2 1.1 5.1 0.1 0.8 6.8 16.3 0.0 29.6 15.6 0.0 8.6 1.0 2.2 0.5 0.0 45.9 0.0 1.1 2.7 5.8 0.0 0.1 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.1 0.0 0.7 0.1 0.0 1.6 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 3.5 1.4 0.8 0.5 1.1 0.2 0.6 0.0 4.8 0.0 0.4 0.1 3.8 4.8 0.0 0.0 123.6 71.0 0.0 48.6 10.1 16.5 0.0 0.2 1.6 9.7 3.9 6.6 0.0 2506.4 397.7 7.6 37.1 0.0 0.0 5.3 0.0 3.8 26.5 2597.0 0.0 0.3 0.0 0.1 4.9 0.0 0.0 59.9 10.2 0.3 0.0 0.0 0.0 14.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 15.3 10.8 0.0 0.0 27.0 0.7 0.1 109.3 0.0 0.0 0.0 8.5 0.0 0.0 1.7 0.4 0.0 13.7 0.1 7.0 16.6 SDF2 ENSG00000132581 "Stromal cell derived factor 2" Q99470 17 28648346-28662189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 211.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042799 Approved Vesicles "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA042799: AB_10794533" "unprognostic (3.91e-1)" "unprognostic (2.79e-1)" "unprognostic (2.03e-1)" "unprognostic (5.77e-3)" "unprognostic (3.90e-2)" "unprognostic (1.88e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.28e-3)" "unprognostic (3.20e-3)" "unprognostic (3.02e-1)" "unprognostic (1.04e-2)" "unprognostic (1.52e-1)" "unprognostic (1.79e-1)" "unprognostic (1.39e-3)" "unprognostic (2.21e-1)" "unprognostic (7.75e-3)" "unprognostic (6.61e-2)" 16.2 32.2 14.6 8.7 14.6 8.8 14.2 14.9 15.2 17.5 18.5 15.7 8.0 14.4 27.2 13.8 17.3 13.0 17.5 14.9 16.3 18.5 23.2 15.4 9.4 15.4 15.3 19.7 19.9 20.1 19.1 20.5 16.0 18.2 11.1 6.6 21.8 15.7 14.7 11.5 13.0 14.4 15.3 16.1 15.3 9.4 15.9 12.7 16.2 12.9 8.1 20.2 14.3 14.9 18.8 54.3 25.2 18.7 107.1 29.6 18.0 53.6 48.4 39.6 49.8 34.6 23.5 8.0 47.8 57.6 36.6 30.5 24.7 22.6 27.8 62.3 29.8 13.7 26.6 28.6 30.9 8.1 17.2 53.7 28.5 38.3 8.8 34.4 39.9 11.0 14.9 19.4 45.1 35.9 20.7 22.2 12.9 48.8 19.2 12.5 37.1 24.8 45.3 29.6 15.6 18.1 42.3 32.4 30.3 37.5 43.7 10.4 45.0 21.0 23.3 24.2 31.2 25.2 35.2 11.9 32.0 12.9 23.9 189.1 45.1 129.1 64.4 39.6 62.6 50.8 52.2 62.8 30.0 44.4 47.1 55.9 203.1 71.1 42.1 62.5 74.2 59.7 14.6 14.6 14.9 15.2 14.9 16.3 15.4 15.3 16.0 15.3 15.9 14.9 61.1 25.6 21.7 10.4 45.5 34.0 59.1 125.6 41.5 26.4 49.4 44.6 13.1 38.6 71.1 42.3 25.0 130.3 74.0 82.8 29.4 74.8 7.4 36.2 43.6 52.2 57.1 37.5 11.1 47.2 109.0 52.6 27.5 44.9 21.0 47.2 53.2 46.2 56.7 13.5 12.2 57.5 71.2 44.9 49.7 3.9 76.1 38.1 37.4 8.4 50.2 49.9 56.7 11.1 17.8 80.4 90.4 66.5 46.2 54.1 88.0 50.7 47.8 31.1 72.3 36.7 48.1 30.5 32.1 40.6 37.6 211.0 53.2 86.0 46.2 86.9 SEC23B "CDA-II, CDAII, CDAN2, HEMPAS" ENSG00000101310 "SEC23 homolog B, COPII coat complex component" Q15437 20 18507520-18561415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008216, HPA069974" Uncertain Supported Vesicles NA Yes 16000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA008216: AB_1079895, HPA069974: AB_2686223" "unprognostic (4.47e-2)" "unprognostic (2.67e-2)" "unprognostic (3.52e-1)" "prognostic favorable (8.25e-4)" "unprognostic (1.24e-1)" "unprognostic (1.33e-1)" "unprognostic (5.44e-3)" "unprognostic (6.01e-2)" "unprognostic (1.39e-1)" "unprognostic (8.75e-2)" "unprognostic (1.97e-1)" "unprognostic (9.97e-2)" "unprognostic (3.91e-2)" "unprognostic (1.72e-2)" "unprognostic (4.26e-2)" "unprognostic (2.81e-2)" "unprognostic (8.21e-2)" 19.6 38.3 18.7 32.0 27.1 36.0 37.8 24.7 25.9 36.2 27.4 31.6 23.8 17.2 53.8 28.4 29.5 23.1 8.5 19.5 22.4 37.4 30.6 29.7 30.5 27.2 23.8 16.9 57.1 50.6 32.6 24.2 27.2 34.8 32.7 40.7 70.9 35.9 4.1 18.2 23.3 18.5 24.5 25.5 38.2 34.8 23.2 27.6 59.5 6.2 38.0 30.5 12.6 38.9 85.0 93.9 49.8 48.7 32.3 36.6 116.0 69.8 45.3 80.0 68.7 84.9 73.8 37.5 44.9 50.4 107.0 88.5 88.5 120.7 86.2 47.5 43.1 64.9 35.6 130.6 70.5 90.2 78.7 28.0 71.8 118.0 151.4 47.6 50.6 34.0 74.8 82.4 55.1 90.7 59.8 49.5 48.0 118.9 101.6 62.4 77.7 122.1 83.0 85.6 78.8 58.0 83.6 188.9 80.6 62.6 82.3 94.4 45.3 53.1 29.8 58.4 87.1 104.2 155.9 60.1 45.3 47.8 74.4 147.9 94.1 106.0 57.2 95.6 78.7 67.2 56.8 61.4 107.9 61.2 51.3 54.0 48.0 78.8 94.9 80.7 75.4 103.7 18.7 27.1 24.7 25.9 19.5 22.4 27.2 23.8 27.2 24.5 23.2 38.9 8.5 16.0 43.5 15.3 24.7 11.5 21.0 34.3 10.2 21.0 21.5 15.6 3.0 20.0 42.5 31.3 16.7 34.3 36.0 26.2 58.7 36.1 95.6 25.4 12.4 11.3 19.7 7.4 17.9 33.4 30.0 11.7 25.0 31.3 15.9 13.6 11.0 25.6 42.9 13.5 20.5 34.7 26.4 38.7 21.0 11.3 14.3 30.3 23.2 15.0 33.1 23.9 9.2 23.1 27.0 31.8 24.2 10.5 59.0 30.1 11.8 53.2 45.4 20.4 19.7 12.4 12.2 48.7 22.1 15.8 14.2 65.8 21.0 16.0 21.5 28.3 SEC23IP p125 ENSG00000107651 "SEC23 interacting protein" Q9Y6Y8 10 119892730-119944657 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038403, HPA043305" Approved Enhanced Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Vesicles "HPA038403: AB_10675796, HPA043305: AB_2678416" "unprognostic (4.05e-2)" "unprognostic (5.01e-2)" "unprognostic (8.70e-2)" "unprognostic (1.35e-1)" "unprognostic (3.12e-1)" "unprognostic (1.07e-1)" "unprognostic (9.52e-3)" "unprognostic (1.78e-1)" "unprognostic (3.36e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" "unprognostic (3.00e-2)" "unprognostic (1.11e-2)" "unprognostic (2.08e-1)" "unprognostic (2.23e-1)" "unprognostic (6.81e-3)" "unprognostic (3.43e-2)" 10.3 9.7 3.5 12.0 3.9 14.1 11.8 6.2 4.6 11.2 6.4 12.6 10.4 11.9 12.1 9.4 8.8 9.6 7.7 4.0 4.0 10.3 12.6 10.2 13.7 4.2 4.3 10.0 11.1 9.8 8.5 12.4 4.0 13.1 13.0 9.0 10.3 9.9 9.8 10.4 9.5 16.4 3.1 11.7 17.5 11.5 4.6 11.1 12.5 8.4 13.4 12.0 8.3 6.3 32.4 30.2 24.3 31.9 22.4 25.3 19.0 27.2 39.5 26.1 31.6 31.0 22.9 30.2 14.7 36.2 32.5 23.9 27.9 29.2 39.5 27.2 28.7 25.1 16.3 34.0 31.0 29.6 29.9 31.4 18.4 30.8 30.5 28.3 36.3 15.5 19.1 21.4 28.7 19.2 25.9 28.2 29.5 28.6 20.9 23.7 44.7 17.3 26.1 25.6 9.6 25.5 25.0 19.9 24.1 24.9 17.5 21.7 29.6 15.8 18.5 23.8 35.1 33.5 32.6 38.7 27.6 37.4 14.1 14.3 10.5 10.3 10.7 16.3 13.9 11.3 10.5 12.4 11.9 9.1 11.1 10.7 3.8 13.0 18.1 7.2 11.9 9.6 3.5 3.9 6.2 4.6 4.0 4.0 4.2 4.3 4.0 3.1 4.6 6.3 15.1 12.8 28.3 21.9 20.9 8.4 19.3 18.1 13.1 17.3 19.1 12.1 17.4 27.1 24.5 18.4 6.2 17.8 18.7 19.7 5.9 16.8 26.1 15.1 22.1 19.9 19.9 21.2 28.3 14.4 18.9 21.4 44.9 15.5 22.1 21.0 14.3 25.5 23.3 11.8 30.2 24.3 26.4 24.6 12.2 24.9 14.0 23.3 8.8 39.4 21.3 14.6 16.5 31.7 37.5 20.2 19.8 15.1 23.7 23.4 16.0 19.2 25.4 23.7 0.0 16.8 17.9 25.0 19.8 19.1 13.9 23.1 18.2 24.2 20.8 21.1 SEC24C KIAA0079 ENSG00000176986 "SEC24 homolog C, COPII coat complex component" P53992 10 73744372-73772161 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA040196, HPA040213" Supported Supported Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040196: AB_10796449, HPA040213: AB_10796451" "unprognostic (5.06e-2)" "unprognostic (1.00e-2)" "unprognostic (2.17e-1)" "unprognostic (3.54e-1)" "unprognostic (8.46e-2)" "unprognostic (7.23e-2)" "unprognostic (9.06e-2)" "unprognostic (4.55e-2)" "unprognostic (1.64e-1)" "unprognostic (2.46e-2)" "unprognostic (1.02e-1)" "unprognostic (1.35e-1)" "unprognostic (7.71e-2)" "unprognostic (8.34e-3)" "unprognostic (2.11e-1)" "unprognostic (3.35e-2)" "unprognostic (1.77e-2)" 27.8 42.9 20.1 31.6 21.2 16.2 27.4 23.1 26.8 42.5 20.7 34.2 27.4 36.4 33.2 69.0 30.7 24.0 34.5 20.4 21.2 29.8 45.8 30.5 31.4 21.4 20.1 33.2 34.9 50.5 45.4 36.4 20.9 37.7 27.6 29.1 36.9 31.1 49.7 35.8 31.7 32.1 18.3 37.1 34.1 27.7 22.7 35.2 34.0 33.9 43.3 35.5 38.8 23.0 72.7 71.8 55.6 99.9 59.2 48.3 45.6 53.6 90.4 70.4 65.7 67.2 47.9 57.3 43.3 72.0 48.1 61.4 78.3 70.7 60.4 76.6 55.6 53.1 50.5 71.2 47.0 80.7 71.1 41.5 76.8 61.8 76.4 89.2 73.6 44.6 64.1 80.8 69.9 64.7 60.4 55.3 34.8 68.3 259.2 65.2 45.0 47.0 46.5 40.8 20.0 51.7 41.9 144.6 60.1 51.7 106.3 70.6 72.7 29.5 53.1 57.7 62.5 82.0 85.9 84.0 84.0 80.8 35.0 28.2 15.8 13.6 27.4 21.4 35.5 12.6 16.2 21.6 18.1 9.4 11.7 15.8 11.5 22.4 19.1 14.8 10.9 22.7 20.1 21.2 23.1 26.8 20.4 21.2 21.4 20.1 20.9 18.3 22.7 23.0 12.1 35.3 28.6 16.3 11.6 8.7 4.7 11.5 6.2 15.1 17.0 14.9 2.3 14.3 17.6 14.7 16.7 17.8 18.6 24.7 3.9 15.1 8.8 10.9 13.0 11.0 19.2 5.9 14.6 19.4 16.4 9.7 19.9 17.0 22.2 20.1 16.4 19.9 17.1 15.2 15.7 18.4 8.2 11.7 8.4 6.0 11.8 12.4 5.4 6.5 12.3 10.3 17.5 14.1 16.8 23.8 14.4 11.7 21.9 10.8 20.0 10.4 8.2 14.7 6.6 10.0 9.7 10.3 8.3 11.5 11.4 25.2 16.9 14.7 16.1 10.9 SEC24D KIAA0755 ENSG00000150961 "SEC24 homolog D, COPII coat complex component" O94855 4 118722823-118838683 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Craniosynostosis, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 118.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041626, HPA053486" Approved Approved Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA041626: AB_10796348, HPA053486: AB_2682166" "unprognostic (9.06e-2)" "unprognostic (3.11e-1)" "unprognostic (3.23e-2)" "unprognostic (8.60e-3)" "unprognostic (1.05e-1)" "unprognostic (1.92e-1)" "unprognostic (1.93e-1)" "unprognostic (2.58e-1)" "unprognostic (9.39e-2)" "unprognostic (3.23e-1)" "unprognostic (1.22e-1)" "unprognostic (6.85e-2)" "prognostic unfavorable (3.42e-6)" "unprognostic (1.09e-3)" "unprognostic (5.64e-2)" "unprognostic (4.30e-3)" "unprognostic (1.37e-1)" 21.1 13.3 2.7 27.2 3.3 17.6 19.4 1.1 4.4 49.0 4.5 24.4 37.5 26.4 36.9 12.4 20.7 31.9 20.1 5.5 4.6 9.5 52.0 22.9 18.4 1.3 2.3 15.3 35.8 10.2 23.3 36.8 1.6 22.0 32.3 1.6 22.9 26.4 5.8 9.9 40.8 41.3 0.6 18.0 29.6 18.4 2.8 14.6 35.6 6.1 21.9 28.9 16.7 2.6 29.6 15.4 35.3 28.6 98.0 130.2 24.8 124.5 136.8 62.1 73.5 16.9 21.3 23.2 17.3 198.7 32.1 10.0 19.4 39.2 66.8 19.4 10.5 25.7 22.8 70.6 99.8 68.6 46.0 77.9 21.6 54.9 89.2 110.3 103.9 15.8 6.7 69.1 98.5 20.6 33.2 20.4 33.3 66.5 24.8 20.1 25.8 41.2 55.6 14.7 20.9 41.8 17.8 89.1 15.3 50.9 12.6 53.9 113.9 48.0 15.3 69.7 28.6 53.1 21.1 38.6 104.5 42.8 68.5 5.8 5.6 16.3 3.1 6.0 6.3 1.7 3.2 4.4 5.8 1.5 2.1 2.7 4.8 5.0 7.4 2.9 4.7 2.6 2.7 3.3 1.1 4.4 5.5 4.6 1.3 2.3 1.6 0.6 2.8 2.6 13.0 3.2 15.3 4.9 19.4 21.0 15.2 19.4 25.6 4.5 19.0 10.2 5.9 17.2 25.5 14.7 0.0 24.3 24.2 18.2 0.0 10.3 101.3 17.4 61.3 23.2 41.3 6.1 57.4 25.3 54.2 49.7 37.2 39.4 8.2 14.2 21.8 70.0 28.1 1.7 6.5 81.0 12.2 34.0 54.4 84.6 45.7 25.1 17.8 48.7 18.3 1.3 13.4 37.7 3.7 13.0 13.6 38.4 118.8 30.7 48.1 4.2 23.0 2.9 26.3 17.5 38.7 14.5 9.7 10.4 17.6 45.0 16.3 34.2 19.1 40.1 SELPLG "CD162, PSGL-1" ENSG00000110876 "Selectin P ligand" Q14242 12 108621895-108633894 "Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 86.6" "Cell type enhanced" "Detected in many" "dendritic cells: 159.7;Kupffer cells: 84.9;Macrophages: 64.8;monocytes: 123.8;NK-cells: 154.5;Plasma cells: 65.1;T-cells: 65.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 136.2;HMC-1: 130.0;JURKAT: 102.2;Karpas-707: 195.1;RPMI-8226: 286.7;U-266/70: 326.8;U-266/84: 214.5" "Low region specificity" "Detected in all" "CAB002431, HPA011256, HPA069062" Enhanced Approved Vesicles NA NA 2700000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "CAB002431: AB_563509, HPA011256: , HPA069062: " "unprognostic (2.32e-2)" "prognostic favorable (1.46e-4)" "unprognostic (3.64e-3)" "unprognostic (1.02e-2)" "unprognostic (6.32e-2)" "prognostic favorable (6.94e-4)" "unprognostic (2.52e-1)" "unprognostic (1.29e-1)" "prognostic favorable (2.92e-4)" "unprognostic (2.26e-1)" "unprognostic (2.12e-2)" "unprognostic (3.24e-1)" "prognostic unfavorable (5.86e-4)" "unprognostic (5.88e-2)" "unprognostic (2.37e-2)" "prognostic favorable (2.74e-4)" "unprognostic (5.44e-2)" 17.5 9.1 12.1 47.4 10.5 21.1 6.9 11.7 12.1 9.2 8.2 9.6 8.6 3.7 2.1 8.6 7.8 17.0 5.0 12.0 14.1 4.0 6.5 40.8 62.2 17.8 13.5 2.8 3.4 4.4 3.0 13.0 16.4 3.3 8.4 0.7 7.0 3.9 2.2 4.7 15.5 11.5 17.0 86.6 11.3 2.2 17.2 52.1 3.4 7.3 30.6 21.5 3.3 24.5 0.5 0.4 1.4 0.8 0.7 1.5 0.8 4.9 4.8 1.8 1.4 0.3 1.9 0.5 1.7 7.4 2.0 0.3 0.1 0.1 1.3 136.2 0.0 45.7 0.2 0.2 0.4 35.1 130.0 1.8 0.5 2.5 0.6 5.0 0.4 102.2 0.8 195.1 6.0 0.0 28.3 18.9 0.2 0.1 1.6 0.3 0.5 286.7 2.9 0.0 0.3 0.0 0.6 0.2 2.2 3.3 0.1 42.6 1.7 2.6 0.8 3.5 1.4 326.8 214.5 6.4 1.5 74.2 1.9 1543.6 297.6 940.2 419.2 509.2 344.3 22.0 396.6 362.9 299.9 22.3 300.3 323.7 1257.2 309.2 762.7 518.3 662.2 1035.5 12.1 10.5 11.7 12.1 12.0 14.1 17.8 13.5 16.4 17.0 17.2 24.5 1.2 3.2 12.4 0.0 11.6 3.4 0.1 0.2 0.0 0.2 0.6 1.4 2.2 4.3 2.7 0.0 0.0 0.5 159.7 0.2 0.0 0.3 8.2 1.8 0.6 2.6 0.0 10.9 0.2 0.2 2.3 2.4 2.6 0.9 29.7 0.4 3.6 2.2 40.1 0.0 0.3 0.0 0.0 84.9 49.6 12.2 0.3 64.8 7.2 15.9 123.8 0.0 154.5 0.0 0.1 0.5 0.0 0.0 65.1 0.1 0.0 0.5 6.4 0.2 0.0 1.2 0.9 0.8 0.5 0.5 1.8 1.0 65.9 0.1 0.0 0.0 SEMA7A "CD108, H-Sema-L, SEMAL" ENSG00000138623 "Semaphorin 7A (John Milton Hagen blood group)" O75326 15 74409289-74433958 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Differentiation, Inflammatory response, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.1;retina: 34.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 68.8;Extravillous trophoblasts: 58.8;Granulosa cells: 65.1;Pancreatic endocrine cells: 91.0;Rod photoreceptor cells: 58.3;Syncytiotrophoblasts: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.8;eosinophil: 3.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.1" "Cell line enhanced" "Detected in many" "HMC-1: 275.8;hTEC/SVTERT24-B: 108.7;U-251 MG: 166.3;U-87 MG: 92.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008210, HPA042273" Uncertain Uncertain Vesicles NA NA 38000000 "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA008210: , HPA042273: AB_10806234" "unprognostic (2.00e-1)" "unprognostic (2.72e-1)" "unprognostic (2.02e-2)" "unprognostic (5.81e-2)" "unprognostic (6.49e-2)" "unprognostic (8.61e-2)" "unprognostic (2.54e-2)" "unprognostic (4.18e-3)" "unprognostic (1.33e-1)" "unprognostic (1.39e-1)" "unprognostic (5.18e-3)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.45e-11)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (6.25e-2)" "unprognostic (2.57e-2)" 2.0 2.5 4.6 7.0 11.0 9.9 1.9 19.1 14.4 2.2 0.9 2.4 1.5 2.9 0.9 4.8 1.4 1.8 2.3 5.1 8.2 2.8 1.6 8.1 13.2 19.9 11.6 7.8 0.9 1.9 2.7 16.3 22.9 1.8 0.9 34.6 2.2 1.2 2.0 8.5 10.8 1.1 10.6 60.1 3.5 29.5 17.2 9.4 1.3 0.3 12.9 8.2 2.5 20.2 16.7 0.2 4.8 1.4 6.0 20.1 39.7 75.2 30.1 15.5 23.8 6.5 26.6 0.1 4.3 34.2 12.6 4.9 1.5 4.8 16.0 1.3 0.9 30.0 0.1 8.3 1.3 0.9 275.8 14.3 0.2 108.7 6.0 39.0 0.2 2.0 17.5 10.1 51.2 1.4 4.3 9.9 5.2 0.4 11.3 0.6 3.3 4.4 6.5 7.1 0.3 0.5 0.5 13.4 6.1 4.1 1.0 6.0 3.0 28.8 19.2 14.1 166.3 1.8 1.3 0.3 92.4 3.4 1.5 1.8 0.0 3.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 4.6 11.0 19.1 14.4 5.1 8.2 19.9 11.6 22.9 10.6 17.2 20.2 1.8 3.2 0.0 1.0 22.6 0.4 1.6 3.1 0.6 13.7 1.2 1.3 1.4 0.0 4.0 1.8 68.8 25.6 5.2 0.6 0.0 19.8 0.5 4.6 1.5 5.3 0.0 21.7 12.4 13.9 58.8 1.8 1.5 10.6 8.2 65.1 0.7 0.7 7.2 1.7 5.9 0.0 0.0 0.3 12.0 2.5 3.7 4.8 8.8 0.0 28.6 6.8 1.0 4.0 16.3 91.0 0.1 1.9 6.4 3.3 0.1 0.1 2.0 58.3 0.0 0.2 9.0 0.9 0.8 0.2 1.4 166.4 5.7 22.0 0.0 24.4 SEPSECS "SLA, SLA/LP" ENSG00000109618 "Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase" Q9HD40 4 25120014-25160550 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "RNA-binding, Transferase, tRNA-binding" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 26.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070409 Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA070409: AB_2686265" "unprognostic (1.83e-1)" "unprognostic (4.09e-2)" "unprognostic (6.37e-3)" "unprognostic (5.86e-2)" "unprognostic (9.63e-2)" "unprognostic (4.61e-3)" "unprognostic (1.82e-3)" "unprognostic (6.33e-2)" "unprognostic (1.24e-1)" "unprognostic (3.34e-1)" "unprognostic (2.52e-1)" "unprognostic (3.56e-2)" "unprognostic (4.45e-3)" "unprognostic (4.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-2)" "unprognostic (2.13e-3)" 4.7 3.5 2.1 1.7 2.1 0.7 4.4 2.0 3.0 4.2 1.6 5.3 4.8 3.8 2.6 3.2 3.8 2.5 2.7 2.0 2.1 8.2 26.1 3.9 2.1 2.2 2.0 4.9 7.4 3.3 3.0 2.8 2.1 3.4 2.7 1.5 3.9 2.0 3.4 5.2 7.6 1.3 2.0 5.6 5.0 4.0 2.1 5.2 4.8 2.6 2.0 3.8 3.5 2.3 1.7 1.0 3.0 1.3 3.9 4.9 2.5 1.1 1.9 2.6 2.3 0.6 2.6 2.9 1.4 1.0 2.6 1.3 3.5 1.2 2.0 1.9 1.3 2.5 1.0 1.8 4.0 2.0 3.3 4.0 4.2 1.0 3.7 3.1 2.5 4.3 7.0 2.5 1.6 0.7 4.4 6.2 2.1 1.8 2.5 1.3 4.3 1.7 3.7 0.7 1.6 2.4 1.3 1.4 4.7 1.9 1.5 5.5 1.0 1.4 0.7 0.7 1.7 2.3 6.2 1.6 1.4 5.4 1.8 0.0 0.2 0.1 0.1 0.6 0.2 0.0 0.2 0.0 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 2.1 2.1 2.0 3.0 2.0 2.1 2.2 2.0 2.1 2.0 2.1 2.3 5.7 0.0 7.2 9.4 6.6 2.4 1.7 3.9 2.8 3.0 5.5 4.3 5.3 22.8 4.3 16.5 0.0 5.5 4.1 10.2 7.9 5.4 30.0 7.3 6.2 6.1 6.1 8.2 5.3 4.7 3.5 4.8 8.2 5.4 3.8 7.9 6.1 42.6 6.1 5.0 7.2 7.7 4.1 8.1 4.5 18.1 3.4 6.6 3.6 14.0 8.0 3.2 4.1 16.1 18.5 5.4 6.0 6.4 6.9 2.7 20.0 20.9 10.2 2.4 0.0 4.9 4.4 26.0 18.3 5.3 3.3 5.9 6.2 7.6 7.8 1.1 SERPINA1 "A1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1" ENSG00000197249 "Serpin family A member 1" P01009 14 94376747-94390693 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 45 "liver: 34022.4" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 42919.3" "Cancer enriched" "Detected in all" 10 "liver cancer: 3850.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 2482.1;intermediate monocyte: 3411.9;neutrophil: 2823.2;non-classical monocyte: 4518.8" "Group enriched" "Detected in all" 5 "granulocytes: 2823.2;monocytes: 4518.8" "Cell line enriched" "Detected in many" 10 "Hep G2: 4769.1" "Not detected" "Not detected" "Region enriched" "Detected in many" 6 "cerebellum: 130.6" "HPA000927, HPA001292, CAB013211, CAB016648, CAB073396" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 2070000000000 140000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB013211: , CAB016648: AB_1611888, CAB073396: , HPA000927: AB_1844761, HPA001292: AB_1844762" "prognostic favorable (1.61e-5)" "unprognostic (3.37e-1)" "prognostic favorable (5.86e-4)" "unprognostic (1.38e-2)" "unprognostic (1.98e-2)" "unprognostic (5.50e-3)" "unprognostic (3.81e-2)" "unprognostic (6.78e-2)" "unprognostic (2.54e-2)" "unprognostic (7.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.54e-1)" "unprognostic (1.23e-2)" "unprognostic (1.89e-1)" "unprognostic (1.30e-2)" "unprognostic (1.17e-2)" "unprognostic (1.96e-1)" 49.1 9.7 7.3 225.0 7.1 157.1 100.6 9.1 21.3 105.7 11.1 151.0 278.6 42.3 5.3 10.1 22.4 352.3 12.5 7.3 11.1 621.2 34022.4 570.7 37.0 20.9 14.4 5.4 201.0 5.2 9.1 26.6 15.8 12.6 178.8 2.6 33.6 140.5 3.7 8.2 760.9 75.7 12.2 313.6 282.5 3.0 16.2 15.0 23.0 11.9 25.2 55.8 9.1 16.9 25.9 0.3 0.0 0.5 1.0 0.0 1.5 0.6 1.7 0.6 1.1 187.8 500.8 2.6 15.6 0.0 1.4 1.9 0.0 10.9 1.2 70.1 0.0 4.3 2.0 4769.1 0.3 16.8 2.3 4.1 5.4 0.3 18.5 1.9 0.0 0.0 3.2 0.4 0.0 0.8 1.1 12.1 2.0 5.5 8.0 1.9 16.7 2.4 300.8 3.0 0.6 1.3 6.4 1.6 1.4 0.4 262.1 2.7 1.6 2.1 59.4 1.9 7.1 3.3 1.8 7.0 4.4 41.8 0.6 10.6 2482.1 634.3 5.5 3411.9 6.8 7.7 3.6 4.1 683.6 3.6 4.3 3.6 2823.2 5.3 4518.8 14.9 4.5 2770.7 7.3 7.1 9.1 21.3 7.3 11.1 20.9 14.4 15.8 12.2 16.2 16.9 2.2 35.3 285.9 0.0 137.4 2.3 1.0 36.3 0.0 0.2 100.8 31.5 5.3 4520.9 165.5 150.8 0.0 1.6 3.9 52.0 68.4 3787.9 0.2 70.0 2.8 57.0 12.1 1227.4 0.0 225.8 4.5 3.6 36.2 51.3 1.3 0.1 938.8 42919.3 167.6 0.0 0.0 742.4 30.5 1454.0 74.1 1.1 0.0 413.3 1.8 1.0 291.7 0.3 9.2 0.0 0.0 2161.6 137.0 0.0 1.5 6.8 5270.0 745.9 108.3 0.2 0.0 0.6 17.4 0.0 0.2 0.6 1.7 6.4 75.5 0.0 83.2 6.7 SERPINA4 "KAL, kallistatin, KLST, KST, PI4" ENSG00000100665 "Serpin family A member 4" P29622 14 94561442-94569913 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 550.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 245.9;Exocrine glandular cells: 93.8;Hepatocytes: 478.5;Pancreatic endocrine cells: 62.1" "Cancer enriched" "Detected in many" 4 "liver cancer: 94.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 28.4" "Not detected" "Not detected" "HPA003607, HPA068939" Approved Uncertain Vesicles "Secreted to blood" NA NA 14500000000 14000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA003607: AB_1079914, HPA068939: " "unprognostic (1.65e-3)" "unprognostic (4.13e-2)" "prognostic favorable (2.95e-4)" "unprognostic (2.09e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-1)" "unprognostic (4.03e-3)" "unprognostic (1.02e-2)" "unprognostic (2.24e-4)" "unprognostic (1.08e-1)" "unprognostic (5.45e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 2.8 0.4 41.0 0.0 1.5 53.4 0.0 0.0 0.0 7.3 550.0 0.0 0.0 0.0 0.0 0.0 116.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.5 0.0 0.0 0.3 0.0 0.0 0.0 27.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 245.9 0.0 3.7 0.0 0.0 0.0 0.0 11.7 30.0 0.0 3.3 0.3 0.3 0.0 2.7 0.0 93.8 0.0 0.0 5.1 4.5 0.0 0.2 5.3 478.5 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 62.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 SERPINB5 "maspin, PI5" ENSG00000206075 "Serpin family B member 5" P36952 18 63476958-63505085 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 216.6;skin 1: 239.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 964.1;Basal prostatic cells: 358.7;Basal respiratory cells: 272.9;Squamous epithelial cells: 535.4;Suprabasal keratinocytes: 1215.3;Urothelial cells: 564.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 124.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1279.3;HBEC3-KT: 425.6;hTCEpi: 875.0;hTERT-HME1: 217.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB009570, HPA019025, HPA019132, HPA020136" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 770000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB009570: AB_2186315, HPA019025: AB_1856726, HPA019132: AB_1856727, HPA020136: AB_1856728" "unprognostic (2.84e-3)" "unprognostic (1.05e-1)" "unprognostic (9.24e-2)" "unprognostic (1.04e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.36e-1)" "unprognostic (3.47e-3)" "prognostic unfavorable (5.71e-6)" "unprognostic (1.28e-1)" "unprognostic (1.84e-6)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (3.14e-1)" "unprognostic (8.38e-2)" 0.6 0.0 0.0 4.3 0.0 0.2 37.1 0.1 0.1 38.5 0.1 4.8 16.7 0.1 0.1 216.6 1.4 2.7 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 9.9 4.5 0.0 37.6 1.7 1.4 239.7 22.1 0.2 0.0 0.0 9.7 2.8 0.0 13.9 0.1 0.0 39.9 90.9 78.7 0.1 80.8 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 73.4 0.1 3.8 0.0 0.1 1279.3 0.0 425.6 0.0 0.0 0.0 0.0 95.8 0.2 0.0 0.0 0.6 0.1 875.0 0.0 217.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 179.9 93.4 0.1 0.0 0.2 0.0 95.1 1.4 0.0 60.2 0.3 0.0 0.3 0.2 0.2 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.2 0.9 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 964.1 358.7 272.9 224.3 0.0 5.1 27.3 0.2 0.0 90.0 3.7 0.0 0.3 0.1 14.2 0.0 0.1 9.0 6.2 0.1 5.4 3.5 0.0 0.3 0.0 0.2 5.8 12.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.3 34.6 0.0 57.6 18.6 0.6 1.8 62.2 0.0 0.0 0.0 0.0 0.0 0.1 16.3 51.7 0.0 2.5 85.4 13.5 0.1 85.4 0.0 0.0 0.0 7.1 6.6 2.2 535.4 1215.3 0.1 4.0 0.1 30.6 564.9 SERPIND1 "D22S673, HC-II, HC2, HCF2, HLS2" ENSG00000099937 "Serpin family D member 1" P05546 22 20774113-20787720 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Chemotaxis, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 1253.1" "Cell type enriched" "Detected in some" 25 "Hepatocytes: 283.7" "Cancer enriched" "Detected in many" 80 "liver cancer: 334.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "Hep G2: 208.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB008639, HPA055767" Supported Approved Vesicles "Secreted to blood" NA NA 50000000000 "Cluster 24: B-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB008639: AB_1618010, HPA055767: AB_2682912" "unprognostic (1.68e-1)" "unprognostic (8.27e-2)" "unprognostic (4.40e-2)" "prognostic favorable (4.09e-4)" "unprognostic (5.42e-2)" "unprognostic (1.23e-1)" "unprognostic (1.12e-3)" "unprognostic (1.56e-1)" "unprognostic (1.13e-1)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (2.88e-1)" "unprognostic (3.94e-9)" "unprognostic (2.01e-1)" "unprognostic (4.66e-2)" "unprognostic (8.36e-3)" "unprognostic (1.46e-1)" 0.3 0.2 0.1 0.0 0.8 0.2 0.4 1.7 0.8 1.0 87.7 0.0 0.0 2.0 0.0 0.1 0.9 0.4 1.1 1.7 0.0 0.3 1253.1 2.5 0.0 0.0 0.0 1.8 0.5 10.1 0.8 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.2 0.0 0.2 0.4 0.1 0.2 0.0 0.7 0.0 0.0 0.8 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 208.2 0.1 0.8 0.5 0.1 0.0 1.6 0.0 0.0 20.4 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.1 2.4 16.5 0.0 0.7 0.0 0.0 3.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.1 0.0 0.1 0.1 0.0 0.2 7.2 0.2 13.9 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.1 0.3 0.0 0.5 0.1 0.0 0.1 0.8 1.7 0.8 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 11.3 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 2.7 1.6 0.0 0.1 2.3 0.0 0.0 1.3 0.0 3.9 283.7 0.1 0.0 0.9 0.0 0.0 6.3 0.0 0.0 1.2 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.5 3.4 0.0 0.0 SERTM1 C13orf36 ENSG00000180440 "Serine rich and transmembrane domain containing 1" A2A2V5 13 36674020-36697839 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.9;endometrium 1: 23.9;fallopian tube: 35.3" "Group enriched" "Detected in some" 7 "Alveolar cells type 1: 9.6;Bipolar cells: 17.9;Endometrial ciliated cells: 5.7;Excitatory neurons: 10.8;Granulosa cells: 14.2;Inhibitory neurons: 17.9" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.7" "Region enhanced" "Detected in many" "hippocampal formation: 18.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HAP1: 1.2;HEK 293: 1.4;NTERA-2: 3.6;SH-SY5Y: 2.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054814, HPA070485" Enhanced Vesicles NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA054814: AB_2682611, HPA070485: AB_2686272" "unprognostic (8.71e-2)" "unprognostic (2.11e-1)" "unprognostic (5.58e-3)" "unprognostic (4.66e-3)" "unprognostic (4.05e-3)" "unprognostic (5.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.63e-2)" "unprognostic (1.00e-8)" "unprognostic (2.51e-2)" "unprognostic (5.60e-2)" "unprognostic (4.44e-2)" 6.2 1.3 7.3 0.0 6.0 0.0 0.6 0.1 8.1 12.3 0.0 0.2 0.1 23.9 0.7 0.0 35.3 0.0 0.4 18.9 0.0 0.1 0.0 5.4 0.0 0.0 1.7 6.4 0.3 1.3 11.5 0.0 3.6 0.9 0.0 3.3 0.0 0.6 0.0 0.2 0.0 17.1 0.3 0.0 0.4 0.3 0.4 0.0 9.2 0.0 0.0 0.3 6.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 6.0 0.1 8.1 18.9 0.0 0.0 1.7 3.6 0.3 0.4 1.2 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.9 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.1 0.0 0.0 0.0 10.8 0.0 0.0 1.3 0.0 0.6 0.0 14.2 0.0 0.0 0.0 1.7 17.9 0.0 0.0 0.0 0.4 0.0 0.3 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SEZ6L ENSG00000100095 "Seizure related 6 homolog like" Q9BYH1 22 26169462-26383597 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 60.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 222.1;Inhibitory neurons: 137.7;Oligodendrocyte precursor cells: 586.1" "Group enriched" "Detected in some" 6 "glioma: 14.6;pancreatic cancer: 3.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 5.9;myeloid DC: 5.7;non-classical monocyte: 5.3" "Group enriched" "Detected in many" 58 "dendritic cells: 5.7;monocytes: 5.9" "Group enriched" "Detected in some" 6 "SCLC-21H: 39.9;SH-SY5Y: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045135 Approved Vesicles NA NA 6700000 "Cluster 51: Monocytes - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA045135: AB_2732518" "unprognostic (1.01e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-1)" "unprognostic (4.95e-2)" "unprognostic (4.49e-2)" "unprognostic (6.47e-2)" "unprognostic (4.19e-1)" "unprognostic (1.09e-2)" "unprognostic (5.02e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-3)" "unprognostic (7.80e-2)" "unprognostic (2.40e-6)" "unprognostic (4.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.39e-4)" "unprognostic (3.18e-1)" 0.1 10.0 25.0 0.5 37.5 0.2 0.0 8.9 50.6 1.1 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 1.3 60.8 52.0 0.0 0.0 0.2 0.0 24.5 23.6 0.0 1.5 0.0 5.8 0.0 19.0 0.2 0.2 4.5 0.2 0.1 0.1 0.3 0.4 0.3 4.0 0.2 1.4 0.3 49.0 0.9 0.1 0.0 0.0 0.1 0.1 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.9 10.7 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 5.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.5 25.0 37.5 8.9 50.6 60.8 52.0 24.5 23.6 19.0 4.0 49.0 24.9 0.0 0.0 0.0 21.9 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.1 0.2 0.0 0.4 222.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 21.9 137.7 0.0 0.0 0.0 2.1 2.0 0.6 1.5 0.0 10.3 3.5 0.7 0.0 586.1 5.5 0.6 0.0 0.4 0.0 0.1 0.0 0.1 0.0 1.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 SH3BGRL MGC117402 ENSG00000131171 "SH3 domain binding glutamate rich protein like" O75368 X 81202102-81298547 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051248 Approved Approved Vesicles NA NA 13000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA051248: AB_2681405" "unprognostic (3.02e-3)" "unprognostic (4.25e-2)" "unprognostic (4.89e-2)" "unprognostic (3.15e-2)" "unprognostic (1.46e-1)" "unprognostic (1.39e-1)" "unprognostic (2.25e-2)" "unprognostic (3.20e-2)" "unprognostic (1.23e-1)" "unprognostic (1.51e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.08e-4)" "unprognostic (2.12e-1)" "unprognostic (3.75e-1)" "unprognostic (1.73e-1)" 112.1 120.0 92.4 101.1 92.4 176.7 170.8 98.1 126.3 146.2 94.3 180.8 87.6 208.5 148.8 130.4 112.3 149.1 61.1 88.0 108.2 126.0 62.6 133.0 154.9 104.8 95.6 130.7 81.3 112.3 83.5 86.4 105.2 153.1 108.5 24.9 112.5 284.9 16.5 67.1 98.1 231.7 104.4 144.4 87.0 54.3 96.1 145.1 104.7 50.2 126.8 178.3 76.0 116.3 1.0 38.2 133.4 154.1 172.1 232.0 9.2 83.4 158.3 30.1 61.1 12.5 114.6 113.7 70.1 122.9 42.4 20.7 95.9 60.0 48.0 98.7 33.3 151.2 59.7 7.4 41.6 107.3 286.0 135.6 42.9 42.4 37.6 231.4 133.8 75.9 53.0 279.6 165.9 53.9 117.0 138.7 105.2 1.4 62.3 102.0 60.9 60.8 155.7 52.8 0.4 58.5 0.1 4.2 77.9 88.0 44.8 321.2 136.9 82.7 34.1 76.4 35.0 64.3 60.6 105.6 95.1 215.9 62.9 793.9 358.5 570.7 124.9 477.3 134.8 236.3 154.7 147.8 306.2 207.4 140.8 148.8 126.7 183.0 560.5 148.0 257.5 462.3 92.4 92.4 98.1 126.3 88.0 108.2 104.8 95.6 105.2 104.4 96.1 116.3 191.3 112.2 92.6 73.8 216.1 126.3 131.5 150.4 83.1 16.2 174.6 150.2 19.7 72.9 106.4 121.4 0.0 7.1 183.9 33.2 344.4 86.9 6.3 74.9 120.0 130.7 93.3 172.9 62.8 74.7 6.0 152.4 63.2 62.6 219.7 92.8 139.9 17.8 431.4 5.0 82.4 87.0 109.9 400.9 430.7 19.2 174.3 379.0 147.7 102.1 459.0 154.2 224.6 82.9 54.3 48.0 104.2 314.1 114.4 83.5 91.2 214.3 113.6 8.5 263.0 132.4 308.8 4.5 5.9 76.0 119.5 5.7 163.4 205.9 90.3 146.4 SHROOM1 "APXL2, KIAA1960" ENSG00000164403 "Shroom family member 1" Q2M3G4 5 132822141-132830659 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 116.9;prostate: 73.9;urinary bladder: 62.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.0;Hepatocytes: 79.2;Proximal enterocytes: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 24.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037690, HPA037691" Uncertain Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA037690: AB_2675613, HPA037691: AB_2675614" "unprognostic (2.50e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (2.66e-1)" "unprognostic (1.45e-2)" "unprognostic (3.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.33e-2)" "unprognostic (3.74e-1)" "unprognostic (3.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (5.72e-6)" "unprognostic (8.22e-2)" "unprognostic (2.91e-2)" "unprognostic (2.88e-2)" "unprognostic (2.26e-3)" 9.3 2.4 25.2 2.6 32.0 0.2 8.2 28.9 26.9 12.6 10.4 20.5 6.1 11.3 2.1 5.1 8.4 6.7 7.6 20.2 23.6 10.7 116.9 10.5 0.6 42.1 30.9 5.6 16.2 4.9 6.8 11.8 33.3 73.9 11.1 3.4 7.0 15.2 1.7 1.5 16.6 3.9 26.1 2.3 10.9 1.7 31.2 0.6 6.9 1.3 0.5 62.4 9.3 55.7 8.6 5.1 0.9 0.8 1.4 4.0 9.0 9.1 7.7 7.0 7.8 11.2 5.7 1.5 12.5 4.9 3.8 0.8 3.1 5.7 4.3 9.5 11.0 0.3 8.7 10.5 4.1 0.7 3.1 1.7 3.0 4.9 3.0 4.8 4.8 0.1 7.3 8.1 6.1 4.8 0.2 4.0 1.4 6.7 8.1 0.5 0.0 0.8 1.2 24.4 5.7 1.5 8.8 0.7 4.9 4.5 5.2 2.9 4.5 8.1 11.7 1.1 11.5 9.2 6.8 0.1 7.9 0.0 2.5 0.2 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 25.2 32.0 28.9 26.9 20.2 23.6 42.1 30.9 33.3 26.1 31.2 55.7 18.3 25.6 22.3 18.9 1.8 1.3 15.4 2.3 3.4 3.7 9.3 5.5 2.2 30.0 11.3 9.2 10.4 6.8 1.0 135.0 1.9 6.0 0.9 7.1 17.3 18.1 22.8 2.7 3.0 10.7 4.8 6.1 33.6 15.1 8.2 9.0 25.0 79.2 6.6 16.8 1.0 28.6 0.0 8.7 5.5 1.1 4.7 4.6 0.0 23.4 8.1 19.9 3.1 6.6 37.5 7.1 53.6 4.9 3.6 31.6 65.5 3.5 9.1 13.3 26.3 2.8 5.1 7.6 5.1 1.8 2.0 2.9 2.5 1.4 35.5 17.3 SLAMF7 "19A, CD319, CRACC, CS1" ENSG00000026751 "SLAM family member 7" Q9NQ25 1 160739057-160754821 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.6;lymphoid tissue: 62.0;stomach 1: 34.2" "Cell type enhanced" "Detected in many" "dendritic cells: 58.3;monocytes: 120.2;NK-cells: 76.2;Plasma cells: 240.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "U-266/70: 283.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015445, HPA055945, HPA061654" Enhanced Approved Vesicles NA NA 1200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB015445: AB_1121905, HPA055945: AB_2682980, HPA061654: AB_2684576" "unprognostic (5.82e-3)" "unprognostic (1.81e-2)" "unprognostic (1.84e-3)" "unprognostic (2.12e-3)" "unprognostic (2.75e-1)" "unprognostic (1.07e-2)" "unprognostic (7.87e-2)" "unprognostic (7.19e-2)" "unprognostic (2.46e-2)" "prognostic favorable (3.93e-4)" "unprognostic (1.08e-1)" "unprognostic (8.13e-2)" "prognostic unfavorable (8.57e-5)" "unprognostic (1.35e-1)" "unprognostic (3.91e-2)" "unprognostic (1.02e-1)" "unprognostic (1.50e-2)" 2.2 3.0 0.2 34.6 0.2 9.7 11.3 0.2 0.6 3.4 0.7 32.6 32.2 2.2 1.7 5.9 2.1 8.7 1.6 0.2 0.2 1.4 7.9 14.5 50.8 0.4 0.2 2.3 1.1 0.4 0.3 1.4 0.6 2.6 28.6 0.0 13.7 2.4 0.5 1.7 25.5 3.7 0.4 42.3 34.2 1.4 0.3 14.7 1.6 0.2 62.0 22.2 2.1 0.5 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 1.0 0.8 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.2 0.0 7.6 0.0 2.5 0.7 0.0 0.2 0.0 7.2 0.0 0.0 0.1 0.0 0.2 1.4 0.0 0.1 0.1 10.0 0.0 0.8 0.0 0.1 0.0 0.0 59.5 0.0 0.0 0.1 0.2 0.0 3.8 0.0 0.2 283.7 26.4 0.2 7.9 0.2 0.0 0.2 5.1 1.4 100.5 34.8 77.3 11.0 10.2 69.0 23.6 2.3 3.0 40.1 3.5 55.5 53.1 89.7 0.0 33.6 0.2 0.2 0.2 0.6 0.2 0.2 0.4 0.2 0.6 0.4 0.3 0.5 0.4 9.6 6.0 0.0 37.4 0.8 1.6 0.3 0.0 0.0 0.2 0.6 1.3 1.5 1.0 0.0 0.0 0.1 58.3 0.2 0.0 0.7 0.0 0.2 0.2 1.4 0.0 3.6 0.0 2.7 0.1 1.7 1.5 0.4 8.8 0.0 0.7 0.6 8.4 0.0 0.0 0.0 0.0 7.3 9.2 0.1 0.0 28.2 19.6 1.0 120.2 0.0 76.2 0.0 0.0 8.6 0.0 0.0 240.9 2.5 0.0 0.2 1.7 0.0 0.0 4.8 1.3 0.0 0.1 0.7 0.4 0.3 37.1 0.0 0.4 3.7 SLC15A3 "hPTR3, PHT2" ENSG00000110446 "Solute carrier family 15 member 3" Q8IY34 11 60937060-60952653 "Metabolic proteins, Predicted membrane proteins, Transporters" "Immunity, Innate immunity, Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 90.6;Kupffer cells: 59.3;Macrophages: 65.5;monocytes: 70.9;Muller glia cells: 211.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 9.0;intermediate monocyte: 12.8;memory B-cell: 4.9;myeloid DC: 6.5;neutrophil: 13.4;non-classical monocyte: 6.4;plasmacytoid DC: 10.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 23.4;BJ hTERT+ SV40 Large T+: 58.0;BJ hTERT+ SV40 Large T+ RasG12V: 74.0;HHSteC: 34.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047880, HPA057642" Approved Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA047880: AB_10959455, HPA057642: AB_2683487" "unprognostic (5.61e-2)" "prognostic favorable (4.07e-5)" "unprognostic (8.79e-2)" "unprognostic (1.67e-2)" "unprognostic (8.48e-2)" "unprognostic (9.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" "unprognostic (1.60e-1)" "unprognostic (1.46e-1)" "unprognostic (9.78e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" 27.5 12.8 11.6 30.7 10.3 35.3 18.2 10.7 15.1 19.7 13.0 34.9 12.0 13.9 3.9 9.3 18.2 19.1 27.1 9.7 13.1 14.9 15.1 52.2 40.1 14.5 10.9 29.2 6.5 4.4 8.4 27.5 13.8 16.7 9.4 17.5 10.0 8.5 6.4 7.9 28.7 15.1 13.5 63.9 18.5 5.5 14.3 12.9 10.5 10.1 15.7 15.6 17.6 15.5 4.3 0.0 2.2 0.0 12.6 9.9 23.4 1.2 21.8 58.0 74.0 0.1 1.9 9.7 0.3 8.8 14.2 1.7 0.0 0.7 3.4 9.4 0.0 0.1 0.1 0.6 34.9 0.0 0.9 6.6 0.0 15.3 0.0 0.1 2.8 0.0 0.0 0.5 3.6 0.5 0.0 1.8 9.8 0.0 0.1 3.9 0.0 3.3 0.0 1.3 0.0 0.1 2.8 9.6 0.4 0.4 4.2 5.7 0.3 0.3 1.2 1.0 0.1 0.0 0.0 3.8 3.9 0.0 13.7 0.0 9.0 1.2 0.1 12.8 0.0 4.9 0.0 0.0 6.5 1.9 0.9 0.9 13.4 0.0 6.4 10.7 0.0 2.4 11.6 10.3 10.7 15.1 9.7 13.1 14.5 10.9 13.8 13.5 14.3 15.5 19.3 9.6 13.2 0.0 7.7 1.7 0.2 4.5 2.2 1.6 0.7 1.4 2.5 1.5 3.7 0.0 0.0 3.6 9.6 1.1 0.0 0.3 7.9 0.1 2.0 12.6 0.0 0.4 0.1 2.2 15.1 5.6 1.1 0.3 15.2 3.7 20.3 3.1 90.6 5.0 0.0 1.2 2.0 59.3 35.5 3.8 8.1 65.5 1.8 4.7 70.9 211.7 1.0 0.0 0.1 2.2 2.8 4.9 2.0 0.1 0.3 0.1 3.1 5.5 13.1 3.1 3.0 4.2 0.7 0.6 1.4 2.6 1.9 4.5 1.1 0.3 SLC16A6 "MCT6, MCT7" ENSG00000108932 "Solute carrier family 16 member 6" O15403 17 68267026-68291267 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 51.0;epididymis: 33.3;retina: 31.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 22.9;Glandular and luminal cells: 27.4;Kupffer cells: 16.7;Macrophages: 21.8;Rod photoreceptor cells: 45.1" "Group enriched" "Detected in many" 6 "breast cancer: 10.9;melanoma: 11.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 13 "SK-MEL-30: 481.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054459, HPA066328" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" Vesicles "HPA054459: AB_2682494, HPA066328: AB_2685660" "unprognostic (2.53e-2)" "unprognostic (2.09e-3)" "unprognostic (8.41e-2)" "unprognostic (6.94e-2)" "unprognostic (3.10e-1)" "unprognostic (5.26e-3)" "unprognostic (5.08e-3)" "unprognostic (5.39e-2)" "unprognostic (1.63e-3)" "unprognostic (1.08e-1)" "unprognostic (1.35e-2)" "unprognostic (1.44e-2)" "unprognostic (8.78e-2)" "unprognostic (2.23e-1)" "unprognostic (8.16e-3)" "unprognostic (2.09e-2)" "unprognostic (9.46e-2)" 1.5 2.7 3.0 7.2 4.8 9.7 5.8 4.3 4.3 1.6 51.0 0.7 0.5 2.6 33.3 10.9 0.9 1.3 0.9 5.0 5.2 0.7 1.4 3.0 5.3 5.1 4.2 1.5 0.5 0.1 1.7 2.3 5.3 0.6 0.8 31.0 2.2 4.2 5.0 4.5 1.2 0.8 2.4 5.7 1.0 2.3 5.2 1.6 3.5 0.7 4.7 2.1 2.6 3.2 2.1 1.8 0.6 0.8 0.4 0.6 14.2 0.8 18.0 1.7 1.2 0.7 2.5 17.6 1.4 0.0 0.2 0.6 2.5 0.0 0.7 5.4 1.3 1.4 2.2 22.3 3.2 5.7 1.1 0.8 0.2 1.0 1.0 1.7 0.8 2.5 1.1 3.8 0.0 18.1 8.5 3.6 0.2 0.1 1.0 0.1 0.4 2.4 0.8 1.5 4.2 0.3 0.8 10.7 481.5 3.8 15.0 3.5 2.7 5.9 1.1 0.5 2.0 4.2 17.5 14.6 36.0 4.6 2.6 0.8 3.1 0.2 1.8 2.7 0.8 0.4 0.6 1.4 1.9 0.0 0.4 0.8 5.4 0.4 1.4 0.3 1.5 0.9 3.0 4.8 4.3 4.3 5.0 5.2 5.1 4.2 5.3 2.4 5.2 3.2 0.6 0.0 2.5 1.6 1.8 0.3 0.2 0.1 1.2 8.2 2.5 0.9 0.8 0.0 4.0 9.2 22.9 0.4 8.4 0.0 0.0 0.0 0.7 4.7 2.5 3.2 0.0 2.7 6.7 0.0 11.5 0.9 0.5 27.4 1.3 0.1 0.7 0.3 5.6 0.0 6.2 0.0 0.0 16.7 7.0 0.3 0.0 21.8 10.6 4.7 11.1 6.2 5.2 0.5 0.8 0.0 0.0 1.9 5.0 0.2 0.0 0.3 1.6 45.1 0.0 0.8 0.3 1.7 0.7 6.7 0.4 0.4 5.3 0.4 0.1 0.2 SLC26A2 "DTD, DTDST" ENSG00000155850 "Solute carrier family 26 member 2" P50443 5 149960758-149993455 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "intestine: 212.0" "Group enriched" "Detected in many" 4 "Distal enterocytes: 2026.2;Glandular and luminal cells: 684.5;Syncytiotrophoblasts: 808.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "EFO-21: 66.1;RPTEC TERT1: 151.7;TIME: 80.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041957, HPA058090" Enhanced Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041957: AB_10795646, HPA058090: AB_2683602" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "unprognostic (3.03e-2)" "prognostic favorable (7.29e-4)" "unprognostic (2.59e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.59e-1)" "unprognostic (5.64e-2)" "unprognostic (1.19e-1)" "unprognostic (7.43e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.70e-1)" "unprognostic (1.77e-1)" "unprognostic (8.12e-2)" "unprognostic (1.06e-1)" 5.2 30.7 2.2 7.8 2.3 2.5 9.2 9.5 3.8 6.3 4.0 212.0 12.9 9.3 22.8 10.7 5.0 5.5 2.8 2.2 3.5 4.9 1.7 7.3 4.0 3.8 3.4 4.8 3.4 37.7 7.1 34.0 3.5 12.2 189.6 20.8 35.8 18.4 3.9 7.8 16.1 9.3 3.8 3.7 3.3 4.2 3.9 4.2 4.5 3.7 5.9 4.7 3.0 3.4 9.5 8.6 10.5 17.3 12.6 8.8 2.5 8.9 8.0 7.0 8.5 44.7 5.1 7.4 66.1 9.5 16.8 6.8 10.0 20.5 12.4 6.0 6.4 9.3 6.7 5.2 9.4 17.3 15.2 9.8 11.8 11.7 15.2 17.3 16.8 9.0 2.4 7.1 29.6 3.0 6.6 9.1 3.2 3.2 13.5 9.5 16.3 3.9 151.7 41.6 3.2 8.1 15.6 3.6 27.2 8.1 7.3 10.0 80.4 16.0 11.8 14.2 10.7 5.2 7.3 4.3 14.7 20.6 23.5 4.9 0.5 0.3 0.9 0.3 1.1 0.5 0.5 0.8 0.7 0.5 0.8 0.9 0.3 1.1 1.6 0.7 1.1 0.5 2.2 2.3 9.5 3.8 2.2 3.5 3.8 3.4 3.5 3.8 3.9 3.4 47.4 44.8 11.3 3.3 8.5 4.6 13.2 22.9 7.4 17.1 23.8 14.6 7.8 7.2 24.2 33.1 16.7 219.2 11.5 2026.2 1.9 6.1 32.7 237.0 92.3 29.8 21.1 16.6 5.4 9.9 7.7 21.5 5.1 684.5 90.0 29.6 17.2 2.0 30.4 6.7 7.9 52.5 20.3 15.3 11.8 15.7 17.4 17.4 90.7 17.8 19.6 15.2 15.5 16.6 6.0 12.1 177.4 12.4 15.2 15.1 91.7 5.1 26.6 84.5 0.0 18.7 13.9 8.7 11.4 73.9 5.1 808.9 14.0 26.3 208.9 5.5 SLC27A4 "ACSVL4, FATP4" ENSG00000167114 "Solute carrier family 27 member 4" Q6P1M0 9 128340527-128361470 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.7;Proximal enterocytes: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007293, CAB009771" Approved Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB009771: AB_2270540, HPA007293: AB_1857062" "unprognostic (7.25e-2)" "unprognostic (1.29e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-3)" "unprognostic (3.74e-2)" "unprognostic (2.03e-1)" "unprognostic (1.85e-3)" "unprognostic (1.31e-3)" "unprognostic (4.51e-1)" "unprognostic (4.69e-2)" "unprognostic (7.72e-2)" "unprognostic (5.07e-2)" "prognostic favorable (2.61e-5)" "unprognostic (7.29e-3)" "unprognostic (2.11e-1)" "unprognostic (3.45e-2)" "unprognostic (8.01e-3)" 11.4 14.7 22.5 8.5 23.7 2.7 11.6 25.4 30.3 17.2 12.4 22.8 66.9 14.4 6.3 61.8 10.4 7.3 20.4 22.7 25.9 28.8 40.0 11.8 6.4 29.4 23.9 8.3 21.6 15.5 12.1 5.6 28.8 13.1 9.4 6.8 16.4 7.5 16.1 41.8 41.1 9.3 19.7 11.6 16.4 25.8 27.1 5.8 15.5 6.2 9.6 15.5 23.5 24.1 20.8 41.8 21.1 28.1 31.5 9.8 23.3 16.7 11.7 20.3 14.5 30.1 20.7 19.1 13.5 19.8 24.8 70.6 25.5 20.7 6.7 19.5 37.2 11.4 35.6 28.5 17.1 21.0 17.8 12.7 29.6 21.2 17.0 9.4 23.1 26.3 27.5 13.7 20.2 56.2 26.0 22.7 9.2 51.6 63.0 30.4 19.6 36.4 38.1 32.0 34.8 19.2 27.6 57.0 20.3 11.3 26.7 8.8 32.4 23.7 22.9 26.6 22.0 11.4 17.4 6.5 24.3 13.0 27.7 0.0 2.5 1.7 4.7 3.3 3.4 2.1 2.9 3.6 4.4 0.9 2.3 2.4 1.0 1.4 4.3 3.9 2.2 2.4 22.5 23.7 25.4 30.3 22.7 25.9 29.4 23.9 28.8 19.7 27.1 24.1 4.7 0.0 1.1 12.7 2.0 2.8 1.4 4.0 1.2 9.6 5.8 3.0 5.2 7.2 2.8 9.2 12.5 6.1 2.1 53.7 1.9 13.1 4.8 3.6 5.2 5.3 13.1 4.0 27.7 16.0 6.8 3.5 14.3 9.3 8.9 5.9 3.6 20.1 11.3 8.4 29.2 18.6 8.2 6.1 1.9 5.4 1.2 5.4 1.8 15.9 10.0 5.0 6.2 8.5 26.4 26.4 30.0 4.1 3.2 3.2 100.6 9.7 1.8 7.8 6.6 4.4 4.4 11.8 7.9 11.9 6.1 5.2 2.4 7.9 25.7 2.8 SLC2A8 "GLUT8, GLUTX1" ENSG00000136856 "Solute carrier family 2 member 8" Q9NY64 9 127397138-127408424 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 145.8;Endometrial stromal cells: 86.5;Late spermatids: 310.1;Spermatocytes: 98.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 75.9" "Lineage enriched" "Detected in all" 5 "dendritic cells: 75.9" "Cell line enhanced" "Detected in many" "CACO-2: 122.9;Hep G2: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011935 Uncertain Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA011935: AB_1849760" "unprognostic (6.49e-2)" "prognostic favorable (2.57e-6)" "unprognostic (9.13e-2)" "unprognostic (1.85e-3)" "unprognostic (4.23e-2)" "unprognostic (9.43e-3)" "unprognostic (2.62e-1)" "unprognostic (1.30e-1)" "unprognostic (6.33e-2)" "unprognostic (1.36e-1)" "prognostic favorable (9.86e-6)" "unprognostic (1.70e-1)" "prognostic favorable (6.55e-6)" "unprognostic (4.25e-2)" "unprognostic (3.55e-1)" "unprognostic (1.59e-3)" "unprognostic (2.04e-3)" 17.3 46.9 23.0 7.5 24.8 3.4 13.1 22.5 22.7 19.7 14.6 42.1 15.7 16.5 13.4 12.0 11.1 6.4 18.2 20.9 18.4 15.4 41.0 11.5 7.4 23.6 23.3 12.0 12.4 6.3 9.9 11.6 20.9 17.8 5.3 3.1 10.2 11.6 33.1 14.2 15.5 6.0 23.5 16.7 23.1 64.2 22.8 1.6 14.8 12.7 3.6 60.6 12.8 25.5 4.9 18.8 8.4 18.5 0.0 0.0 26.3 7.4 4.9 11.5 6.9 122.9 4.5 7.5 16.3 3.9 18.4 25.4 10.1 11.7 2.9 7.2 16.2 1.1 15.4 73.3 10.5 0.0 7.8 0.2 10.6 1.1 4.7 5.7 9.0 10.2 8.1 16.4 4.7 35.1 0.0 0.2 13.4 27.1 29.4 2.9 11.5 20.7 11.0 50.6 13.8 9.6 17.6 29.8 6.6 10.6 19.2 4.3 7.9 0.0 11.7 0.8 16.7 49.7 50.6 11.3 7.8 0.0 8.9 0.0 7.0 16.6 10.4 13.5 7.7 5.0 3.3 7.1 10.6 4.7 0.7 2.5 0.5 3.3 12.5 75.9 15.0 4.7 23.0 24.8 22.5 22.7 20.9 18.4 23.6 23.3 20.9 23.5 22.8 25.5 10.8 9.6 8.4 6.2 6.4 11.1 7.4 8.5 9.6 9.5 12.2 10.7 7.6 8.6 7.8 5.5 10.4 78.3 24.5 12.5 15.6 15.6 145.8 6.0 86.5 10.2 12.1 7.0 7.7 16.7 12.8 11.0 10.7 8.0 7.0 15.9 12.1 26.8 75.0 6.7 7.7 14.9 2.0 16.7 8.5 310.1 10.8 14.9 26.6 2.8 7.2 13.4 13.4 2.0 5.4 17.4 22.3 11.7 8.5 14.1 35.0 14.0 5.3 8.4 13.1 11.6 8.6 98.7 15.5 8.7 10.5 67.3 5.9 9.3 19.8 5.8 SLC30A2 ZNT2 ENSG00000158014 "Solute carrier family 30 member 2" Q9BRI3 1 26037252-26046118 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pancreas: 99.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 31.0;Endometrial ciliated cells: 30.5;Glandular and luminal cells: 93.7;Proximal tubular cells: 36.2;Syncytiotrophoblasts: 85.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 19.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 2.1;RPTEC TERT1: 4.5;WM-115: 3.5" "Region enriched" "Detected in single" 5 "olfactory bulb: 1.2" "Not detected" "Not detected" HPA017979 Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Vesicles "HPA017979: AB_1857085" "unprognostic (4.87e-2)" "unprognostic (6.70e-2)" "unprognostic (3.79e-2)" "unprognostic (1.79e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-2)" "unprognostic (2.25e-2)" "unprognostic (2.59e-1)" "unprognostic (3.67e-2)" "unprognostic (1.02e-1)" "unprognostic (6.99e-2)" "unprognostic (1.10e-1)" "prognostic favorable (2.86e-6)" "unprognostic (9.38e-2)" "unprognostic (3.50e-2)" "unprognostic (1.17e-1)" "unprognostic (3.01e-2)" 0.1 1.2 0.4 0.3 0.5 0.6 1.1 1.9 1.0 0.2 0.3 0.5 0.5 0.5 0.3 0.1 0.4 6.7 6.3 0.4 0.3 20.2 0.1 0.2 0.2 0.2 0.0 0.1 99.8 2.2 0.0 4.5 0.1 0.2 0.1 0.5 1.6 2.3 3.8 1.0 0.8 0.1 0.0 0.3 0.3 0.2 0.6 0.0 19.8 0.7 0.1 0.5 0.0 0.2 0.1 0.1 0.0 0.4 0.1 0.0 2.1 0.1 0.1 0.0 0.0 0.3 0.4 0.1 0.4 0.0 0.1 0.3 0.1 0.2 0.0 0.3 0.1 0.2 0.2 0.0 0.0 0.3 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.7 0.0 0.3 0.2 0.3 0.3 0.2 0.0 0.1 0.3 0.3 4.5 0.1 0.4 0.1 0.3 0.5 0.1 0.7 0.3 0.1 0.2 0.2 0.5 0.2 0.1 0.3 0.2 0.3 0.2 0.2 3.5 0.9 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.6 0.3 0.1 0.2 0.1 0.0 0.4 0.5 1.9 1.0 0.4 0.3 0.2 0.0 0.1 0.0 0.6 0.2 0.2 3.2 3.0 0.0 0.6 0.4 0.7 0.0 0.0 4.5 9.1 0.4 13.9 8.6 0.0 9.2 0.0 31.0 0.1 0.5 5.9 11.5 0.0 30.5 9.7 1.0 0.0 0.0 0.0 21.1 2.8 0.5 0.0 93.7 4.5 0.1 0.0 0.0 3.6 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.3 0.9 3.6 0.0 1.0 0.7 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.6 3.9 36.2 0.0 2.3 6.6 2.1 1.0 0.2 0.4 0.0 0.9 85.1 0.9 0.1 1.1 0.7 SLC35B2 UGTrel4 ENSG00000157593 "Solute carrier family 35 member B2" Q8TB61 6 44254096-44257890 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029638 Approved Approved Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA029638: AB_10602402" "prognostic unfavorable (7.90e-4)" "unprognostic (2.47e-3)" "unprognostic (2.30e-1)" "unprognostic (1.39e-2)" "unprognostic (2.36e-1)" "unprognostic (1.65e-2)" "prognostic unfavorable (8.59e-5)" "unprognostic (3.84e-1)" "unprognostic (2.51e-1)" "unprognostic (7.03e-3)" "unprognostic (4.27e-2)" "prognostic favorable (6.07e-4)" "unprognostic (3.60e-2)" "unprognostic (1.13e-1)" "unprognostic (4.07e-1)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" 20.1 36.7 21.2 19.6 25.7 18.4 25.2 27.0 42.3 23.3 24.1 27.1 19.6 28.5 29.5 17.5 26.2 30.0 26.4 19.5 23.3 30.3 30.6 21.7 21.5 25.8 25.1 21.3 41.8 42.5 14.6 25.0 25.6 24.0 28.8 14.6 46.4 27.4 22.4 21.9 23.9 29.7 26.1 24.7 30.6 14.7 26.1 18.5 24.4 23.7 22.3 28.1 19.5 30.9 87.2 48.8 61.4 117.6 106.4 102.3 44.1 95.1 152.3 89.3 109.4 43.3 79.3 19.2 81.9 117.3 97.7 81.1 42.5 106.3 64.4 57.4 53.3 39.8 37.9 59.5 94.1 85.2 61.5 107.0 112.1 85.5 43.1 129.1 67.4 43.2 56.8 81.4 112.5 106.9 32.5 71.0 27.2 271.3 58.9 30.9 38.3 100.2 100.3 65.5 75.4 71.4 45.9 52.2 109.6 37.6 93.3 75.7 65.8 71.0 46.2 71.3 83.3 62.4 75.7 45.6 95.6 67.6 147.5 51.9 14.5 23.5 33.1 11.4 28.3 19.7 18.6 25.2 12.9 13.2 16.6 22.0 1.3 20.3 3.9 23.5 16.4 17.7 21.2 25.7 27.0 42.3 19.5 23.3 25.8 25.1 25.6 26.1 26.1 30.9 8.0 6.4 11.5 8.5 19.2 13.5 32.0 58.3 23.9 9.7 31.6 30.1 7.8 37.1 34.8 27.6 2.1 59.2 15.3 15.2 13.7 84.0 0.6 16.0 17.8 11.1 19.7 10.5 3.5 73.8 52.1 27.5 14.3 19.5 34.9 11.9 13.6 18.7 38.4 10.1 4.3 21.6 57.0 11.4 10.8 2.3 23.3 22.0 53.4 4.7 22.0 38.8 23.7 9.5 13.8 67.4 25.9 19.9 23.3 36.3 18.8 13.5 18.4 12.5 0.0 18.3 24.5 21.0 60.8 17.4 13.9 35.2 14.0 14.8 31.5 24.2 SLC38A9 FLJ90709 ENSG00000177058 "Solute carrier family 38 member 9" Q8NBW4 5 55625845-55773194 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 57.8" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 182.5;Early spermatids: 262.6;Syncytiotrophoblasts: 619.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 110.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043785, HPA061702" Uncertain Supported Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA043785: AB_10961859, HPA061702: " "unprognostic (4.80e-2)" "unprognostic (1.18e-1)" "unprognostic (3.26e-2)" "prognostic unfavorable (7.24e-5)" "unprognostic (2.49e-1)" "unprognostic (8.19e-2)" "unprognostic (8.35e-2)" "unprognostic (7.95e-2)" "unprognostic (5.47e-2)" "unprognostic (9.44e-2)" "unprognostic (1.74e-1)" "unprognostic (4.87e-1)" "unprognostic (4.18e-3)" "unprognostic (1.76e-1)" "unprognostic (2.25e-1)" "unprognostic (2.84e-2)" "unprognostic (1.12e-1)" 6.1 4.8 5.4 8.8 7.3 7.1 8.2 8.1 6.3 6.5 4.1 9.4 8.1 6.6 6.6 8.4 5.0 8.3 3.8 4.3 6.6 7.4 16.6 8.0 11.2 6.3 5.9 5.4 12.1 10.7 3.3 57.8 6.6 6.1 9.8 10.0 6.4 6.0 4.4 7.6 6.6 8.5 5.5 8.4 8.1 19.2 6.3 8.8 7.7 3.8 14.5 8.4 4.8 8.9 17.9 17.3 17.1 20.0 22.0 20.4 110.0 16.5 21.3 18.3 30.4 29.5 27.2 31.6 28.6 12.7 32.1 22.5 20.2 18.2 22.8 15.4 18.4 10.8 16.4 18.7 31.1 18.9 10.8 26.3 21.0 20.2 25.7 13.7 20.0 21.3 20.9 18.6 16.5 15.0 23.6 16.4 29.4 7.2 15.6 17.6 28.6 32.2 24.7 14.0 8.1 14.5 17.3 9.3 25.4 24.0 20.1 34.4 29.6 3.6 11.7 26.8 16.6 20.5 47.6 20.8 10.9 17.4 11.4 3.3 9.3 5.5 5.2 8.7 7.5 7.4 4.5 6.1 8.4 4.2 6.2 5.3 2.0 7.7 6.9 8.0 5.9 4.9 5.4 7.3 8.1 6.3 4.3 6.6 6.3 5.9 6.6 5.5 6.3 8.9 7.3 6.4 3.1 21.9 14.2 3.2 4.2 8.5 2.8 6.6 5.7 3.9 2.8 11.5 9.8 9.2 8.4 182.5 10.4 8.9 1.9 8.9 262.6 4.4 9.2 8.1 4.2 8.4 56.2 11.4 71.5 7.2 8.6 7.3 2.5 8.0 10.4 22.1 26.3 1.7 57.3 4.3 8.2 10.0 8.0 82.4 7.5 11.7 5.4 38.4 11.0 5.6 4.1 55.8 103.2 10.9 9.7 4.9 8.4 4.6 4.4 7.2 6.3 7.4 6.6 3.3 7.0 15.8 6.5 8.1 3.4 619.9 8.7 4.0 5.2 4.7 SLC39A3 ZIP3 ENSG00000141873 "Solute carrier family 39 member 3" Q9BRY0 19 2732204-2740028 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 100.3" "Group enriched" "Detected in all" 4 "Early spermatids: 302.1;Late spermatids: 433.3;Spermatocytes: 185.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 409.6" "Low region specificity" "Detected in all" "HPA042139, HPA058526" Uncertain Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA042139: AB_10793875, HPA058526: AB_2683743" "unprognostic (1.81e-1)" "unprognostic (1.47e-2)" "unprognostic (1.16e-1)" "prognostic favorable (9.76e-5)" "unprognostic (2.26e-1)" "unprognostic (2.44e-2)" "unprognostic (9.88e-3)" "unprognostic (1.01e-1)" "unprognostic (6.03e-2)" "unprognostic (3.66e-2)" "unprognostic (4.37e-3)" "unprognostic (4.07e-2)" "unprognostic (1.75e-3)" "unprognostic (9.22e-3)" "unprognostic (6.58e-2)" "unprognostic (7.97e-2)" "unprognostic (1.80e-2)" 17.9 27.0 19.0 14.7 22.0 46.3 17.4 18.3 23.6 19.6 14.8 18.4 16.7 25.1 30.5 17.3 23.2 15.3 23.3 23.6 18.5 19.8 32.8 16.3 19.1 20.0 18.0 13.5 20.7 34.7 27.2 12.3 18.7 19.3 14.4 10.2 21.3 17.8 22.9 14.9 16.5 23.0 16.7 22.7 17.4 100.3 20.1 21.8 20.5 24.7 16.1 22.3 14.4 18.6 53.3 44.1 32.5 80.3 66.1 45.0 30.6 38.6 46.5 71.3 72.4 47.8 35.0 32.2 23.6 68.2 56.3 42.9 50.2 52.7 44.3 0.4 37.1 144.4 31.4 48.9 72.1 123.2 209.5 40.6 83.3 53.1 43.3 25.6 36.9 61.8 162.8 147.6 48.6 35.2 61.4 99.0 34.6 48.8 59.4 81.4 20.9 100.7 34.1 42.7 44.1 40.3 33.9 24.4 82.4 20.9 42.4 162.7 22.4 49.5 27.0 75.6 56.4 38.7 66.6 32.6 37.4 409.6 59.7 41.1 36.0 67.9 35.9 35.6 30.1 53.3 30.5 29.2 48.9 53.7 24.5 29.2 16.7 29.7 34.1 83.9 21.2 35.2 19.0 22.0 18.3 23.6 23.6 18.5 20.0 18.0 18.7 16.7 20.1 18.6 18.1 3.2 2.8 2.6 31.6 10.3 16.6 37.1 2.2 19.2 25.5 23.6 7.8 24.3 22.6 7.3 8.4 37.5 16.8 20.2 17.6 50.7 302.1 17.8 16.4 21.8 24.0 57.6 5.0 61.8 56.3 18.4 10.7 13.3 24.8 24.2 21.8 31.0 64.9 48.8 5.9 19.7 32.6 25.7 12.9 433.3 21.5 39.3 24.9 4.7 26.7 33.5 26.8 6.6 5.6 46.9 25.8 27.8 12.9 33.3 23.0 23.6 17.6 22.0 26.3 14.0 23.6 185.8 29.7 10.5 9.8 26.4 14.5 29.4 25.6 17.6 SLC48A1 "FLJ20489, hHRG-1, HRG1" ENSG00000211584 "Solute carrier family 48 member 1" Q6P1K1 12 47753916-47782751 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 135.6" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 102.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065396, HPA073994" Approved Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "HPA065396: , HPA073994: " "unprognostic (9.60e-2)" "prognostic favorable (4.27e-4)" "unprognostic (1.13e-2)" "unprognostic (1.18e-2)" "unprognostic (1.22e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (9.39e-5)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (9.88e-2)" "unprognostic (1.54e-2)" "unprognostic (6.63e-3)" "prognostic favorable (1.34e-6)" "unprognostic (1.45e-1)" "unprognostic (5.96e-2)" "unprognostic (1.52e-1)" "unprognostic (2.72e-2)" 27.5 37.4 98.8 6.9 131.6 12.3 27.6 116.7 104.3 26.8 58.5 26.8 7.4 20.2 16.2 28.9 28.4 15.4 29.0 96.2 99.8 44.1 15.2 22.3 7.0 125.5 127.0 53.1 19.5 29.4 17.7 17.7 113.4 20.4 10.6 11.2 20.2 22.7 29.9 22.0 14.3 16.6 103.2 25.8 22.1 9.9 126.8 7.9 52.6 21.5 8.2 27.6 22.6 135.6 11.9 36.3 5.7 42.8 36.4 15.5 12.3 8.3 18.3 7.8 8.0 11.7 31.0 7.2 102.7 23.3 15.5 45.4 7.3 9.6 6.0 59.1 6.8 49.4 30.4 16.1 20.8 13.3 27.9 9.2 19.3 11.2 13.6 40.6 22.1 20.0 13.1 28.3 5.1 24.7 6.5 13.7 3.9 21.9 17.1 6.0 1.6 39.0 31.5 31.3 7.3 3.3 11.0 13.8 7.8 10.2 46.0 12.2 12.3 10.9 14.3 21.1 6.0 21.6 14.3 2.2 14.2 62.8 6.7 0.1 17.9 12.4 5.2 13.5 4.7 10.4 6.4 5.5 12.9 9.9 7.7 6.4 36.7 2.0 7.7 2.6 5.5 6.3 98.8 131.6 116.7 104.3 96.2 99.8 125.5 127.0 113.4 103.2 126.8 135.6 35.2 9.6 13.5 35.3 6.2 6.6 9.7 6.4 22.2 11.1 15.5 15.2 16.4 20.0 5.5 51.5 2.1 9.5 2.3 9.0 23.5 10.4 8.5 10.9 6.2 22.3 8.4 53.0 9.1 9.8 2.3 15.6 4.6 18.0 1.3 16.4 16.8 11.8 24.1 15.2 8.3 13.5 6.1 18.0 9.9 12.5 32.6 14.1 5.4 8.4 28.4 26.8 2.1 11.1 100.3 6.6 5.2 23.0 10.1 12.9 9.2 34.9 2.3 11.2 6.6 11.9 11.6 4.1 10.5 20.9 11.9 3.6 3.3 18.0 7.5 11.6 SLC49A4 "DIRC2, FLJ14784, RCC4" ENSG00000138463 "Solute carrier family 49 member 4" Q96SL1 3 122795069-122881139 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 44.0;Extravillous trophoblasts: 61.2;Syncytiotrophoblasts: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072579 Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA072579: AB_2686536" "unprognostic (1.40e-1)" "unprognostic (8.53e-3)" "unprognostic (1.20e-1)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (5.36e-2)" "prognostic unfavorable (7.48e-4)" "unprognostic (9.74e-2)" "unprognostic (2.58e-1)" "unprognostic (3.95e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.87e-1)" "prognostic favorable (8.81e-11)" "unprognostic (2.36e-1)" "unprognostic (2.64e-1)" "unprognostic (1.73e-1)" "unprognostic (7.13e-2)" 4.4 5.0 4.9 2.7 5.1 5.9 3.1 4.9 5.3 3.0 6.2 4.1 1.9 2.6 3.8 5.6 3.1 3.7 6.4 5.7 5.9 4.6 3.5 5.2 2.0 4.8 5.6 2.2 6.5 12.7 2.4 7.6 5.6 4.9 4.5 5.7 3.7 3.6 15.9 6.6 2.6 2.7 5.2 2.8 3.1 2.5 5.6 1.9 5.2 14.0 2.5 4.0 2.6 5.9 7.4 6.1 5.9 3.3 7.5 6.1 19.6 3.1 6.7 4.9 5.0 14.4 8.0 1.0 3.9 3.5 10.9 10.5 4.3 5.6 4.7 1.6 3.2 1.2 3.3 6.2 5.5 0.7 0.7 5.0 15.0 3.5 5.9 7.6 5.6 2.0 0.7 1.3 6.3 3.3 0.9 0.8 5.3 2.5 9.8 2.0 13.3 1.5 7.0 8.4 6.1 4.6 9.1 4.1 8.4 3.7 4.8 1.6 8.0 7.6 2.8 4.6 2.6 1.3 1.2 0.4 3.8 1.3 4.2 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.9 0.0 0.2 0.0 0.0 0.0 4.9 5.1 4.9 5.3 5.7 5.9 4.8 5.6 5.6 5.2 5.6 5.9 3.5 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 44.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 61.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 226.6 0.4 0.0 0.0 0.0 SLC66A1 "FLJ20320, LAAT-1, LAAT1, PQLC2" ENSG00000040487 "Solute carrier family 66 member 1" Q6ZP29 1 19312326-19329300 "Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Cytotrophoblasts: 26.9;Extravillous trophoblasts: 17.0;Hofbauer cells: 37.4;Syncytiotrophoblasts: 60.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057810 Approved Supported Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA057810: AB_2683535" "unprognostic (7.84e-3)" "unprognostic (6.56e-2)" "unprognostic (6.54e-2)" "prognostic favorable (3.50e-4)" "unprognostic (3.77e-3)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.64e-5)" "unprognostic (2.61e-1)" "unprognostic (4.47e-2)" "unprognostic (1.04e-1)" "unprognostic (1.42e-3)" "unprognostic (3.82e-2)" "unprognostic (4.70e-3)" "unprognostic (8.64e-2)" "unprognostic (2.07e-1)" "unprognostic (6.56e-2)" "unprognostic (4.46e-2)" 10.7 24.8 12.4 5.6 13.8 13.1 10.7 17.9 14.7 12.9 11.3 11.6 10.7 10.8 9.1 9.8 10.1 6.9 11.3 12.5 13.0 15.2 26.6 10.7 7.9 15.7 13.6 11.0 17.4 7.9 23.2 7.1 14.7 14.2 4.7 12.1 10.5 6.3 14.2 14.1 16.7 5.7 12.1 14.6 14.5 18.6 14.2 4.3 13.5 6.1 5.6 9.9 10.6 15.1 14.6 15.0 13.9 22.4 13.3 12.4 17.6 18.0 24.6 24.7 20.7 22.1 18.0 4.7 23.0 13.3 34.2 10.6 13.7 16.2 11.1 9.9 16.5 3.6 13.4 24.0 37.8 3.1 6.3 20.6 16.7 34.9 11.1 13.8 9.6 8.1 26.8 10.7 24.0 12.8 2.1 10.2 13.3 5.2 13.3 8.1 17.5 8.2 18.9 9.4 17.2 14.3 13.5 9.1 35.5 12.4 15.1 35.8 12.8 20.4 11.8 35.0 16.1 18.4 13.8 2.7 25.1 18.3 17.3 1.3 10.5 10.3 3.7 9.1 2.6 6.0 3.9 3.1 13.7 5.4 1.1 2.3 6.4 4.1 13.8 20.5 3.8 4.5 12.4 13.8 17.9 14.7 12.5 13.0 15.7 13.6 14.7 12.1 14.2 15.1 2.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 26.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 17.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 60.5 0.1 0.0 0.0 0.0 SLC6A12 BGT-1 ENSG00000111181 "Solute carrier family 6 member 12" P48065 12 190077-214570 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 35.2;kidney: 36.0;liver: 81.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 46.0;Hepatocytes: 22.7;monocytes: 10.7" "Cancer enhanced" "Detected in many" "liver cancer: 8.8;renal cancer: 11.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 50 "classical monocyte: 5.7;intermediate monocyte: 5.7;myeloid DC: 2.4;neutrophil: 3.0;non-classical monocyte: 7.9" "Group enriched" "Detected in many" 45 "dendritic cells: 2.4;granulocytes: 3.0;monocytes: 7.9" "Cell line enhanced" "Detected in some" "Hep G2: 7.2;RPTEC TERT1: 13.8;SuSa: 2.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034973 Approved Approved Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Vesicles "HPA034973: AB_10610427" "unprognostic (3.48e-1)" "unprognostic (4.73e-2)" "unprognostic (8.69e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.70e-1)" "unprognostic (1.09e-1)" "unprognostic (1.88e-2)" "unprognostic (8.30e-2)" "unprognostic (6.96e-3)" "unprognostic (2.70e-2)" "unprognostic (1.85e-2)" "unprognostic (3.68e-1)" "prognostic favorable (2.70e-6)" "unprognostic (2.30e-1)" "unprognostic (4.92e-4)" "unprognostic (3.35e-1)" "unprognostic (4.31e-4)" 0.2 0.4 22.6 1.1 23.3 0.1 0.4 18.0 35.2 0.8 12.4 0.7 4.5 1.1 6.8 0.0 3.4 1.0 0.3 18.5 21.5 36.0 81.5 2.4 0.5 19.8 25.2 0.3 1.6 0.4 0.8 0.5 20.9 0.1 1.8 0.5 0.1 0.0 0.1 0.2 0.8 0.9 16.5 0.5 2.4 1.6 22.4 0.3 6.3 0.0 0.3 0.4 0.3 17.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.8 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 7.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.8 0.1 0.0 0.4 0.0 0.0 0.1 2.9 0.2 0.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 5.7 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 3.0 0.0 7.9 0.0 0.0 1.9 22.6 23.3 18.0 35.2 18.5 21.5 19.8 25.2 20.9 16.5 22.4 17.7 0.1 0.0 0.5 4.2 0.6 0.1 0.0 0.0 0.0 0.5 0.9 0.6 0.7 0.0 0.1 46.0 0.0 0.0 0.0 1.6 1.9 0.0 4.6 3.5 1.7 0.2 0.0 0.0 0.4 0.4 0.0 0.6 2.0 8.8 0.0 0.1 0.7 22.7 2.4 0.0 0.3 1.7 0.0 1.9 2.5 6.2 0.6 1.6 0.0 8.4 10.7 5.2 0.0 0.5 9.2 0.0 1.2 0.0 0.0 0.0 0.0 8.0 0.0 0.4 6.6 0.6 0.4 2.3 4.5 0.0 0.4 0.8 0.1 0.1 1.0 0.1 SLC6A14 ENSG00000268104 "Solute carrier family 6 member 14" Q9UN76 X 116436606-116461458 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" Obesity "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.0;salivary gland: 20.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 115.7;Basal respiratory cells: 94.9;Club cells: 225.6;Pancreatic endocrine cells: 170.4;Respiratory ciliated cells: 58.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 1.7;Hep G2: 3.4;OE19: 1.2" HPA003193 Uncertain Approved Vesicles NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA003193: AB_2190122" "unprognostic (3.06e-2)" "unprognostic (3.55e-2)" "unprognostic (8.49e-2)" "unprognostic (1.00e-3)" "unprognostic (1.30e-3)" "unprognostic (1.49e-2)" "unprognostic (7.41e-3)" "unprognostic (3.67e-3)" "unprognostic (2.66e-1)" "unprognostic (1.83e-2)" "prognostic unfavorable (9.74e-4)" "unprognostic (1.34e-2)" "unprognostic (3.89e-2)" "unprognostic (2.08e-2)" "unprognostic (1.71e-1)" "unprognostic (1.59e-1)" 0.0 0.0 0.1 2.2 0.0 0.1 7.7 0.3 0.1 7.0 0.0 1.4 0.9 0.2 0.0 2.3 0.2 0.8 0.0 0.1 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 1.0 0.7 0.0 20.6 1.3 0.0 3.2 0.6 0.1 0.0 0.0 3.8 0.1 0.0 0.0 0.0 0.0 1.1 1.6 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 22.4 115.7 0.0 0.1 0.1 0.3 94.9 0.0 0.0 17.6 11.6 0.2 0.0 225.6 0.0 0.0 0.0 0.1 18.1 0.0 17.6 0.1 0.2 0.0 0.5 2.4 0.0 0.0 32.0 0.0 1.0 10.7 0.4 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 6.1 0.0 0.0 0.1 0.0 0.5 16.0 0.0 0.0 0.0 0.0 0.0 0.0 170.4 10.2 0.0 0.0 10.5 0.2 0.0 58.1 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.4 0.0 0.4 0.0 8.9 23.4 SLC6A3 "DAT, DAT1" ENSG00000142319 "Solute carrier family 6 member 3" Q01959 5 1392794-1445440 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, Dystonia, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 73 "brain: 60.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.3;Cardiomyocytes: 1.2;Smooth muscle cells: 1.4" "Cancer enriched" "Detected in some" 18 "renal cancer: 25.7" "Region enriched" "Detected in some" 26 "midbrain: 60.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "midbrain: 80.6;thalamus: 29.0" "Region enriched" "Detected in some" 152 "midbrain: 302.6" "HPA012763, HPA013602, CAB016249, CAB078172" Enhanced Supported Approved Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: Cardiomyocytes - Nuclear processes" Vesicles "CAB016249: AB_627402, CAB078172: AB_2665810, HPA012763: AB_2732405, HPA013602: AB_1847484" "unprognostic (2.25e-4)" "unprognostic (2.22e-1)" "unprognostic (8.45e-2)" "unprognostic (5.24e-2)" "unprognostic (7.75e-2)" "unprognostic (1.41e-2)" "unprognostic (4.64e-5)" "unprognostic (9.31e-2)" "unprognostic (7.89e-2)" "unprognostic (4.81e-2)" "unprognostic (1.30e-1)" "unprognostic (2.12e-2)" "prognostic unfavorable (3.40e-7)" "unprognostic (6.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.22e-2)" "unprognostic (4.74e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.5 0.0 0.3 0.0 0.0 60.6 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 2.3 0.1 0.8 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 60.6 0.3 0.0 2.3 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 SLC7A11 xCT ENSG00000151012 "Solute carrier family 7 member 11" Q9UPY5 4 138164097-138242349 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.5" "Cell type enhanced" "Detected in many" "Astrocytes: 368.6;Microglial cells: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "hTCEpi: 84.2;TIME: 95.2;WM-115: 138.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064215 Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA064215: AB_2685213" "unprognostic (3.55e-3)" "unprognostic (4.64e-3)" "unprognostic (2.43e-2)" "unprognostic (7.18e-3)" "unprognostic (2.59e-1)" "unprognostic (8.80e-3)" "unprognostic (2.07e-8)" "unprognostic (1.98e-2)" "unprognostic (1.09e-2)" "prognostic favorable (1.77e-4)" "unprognostic (1.90e-2)" "unprognostic (4.07e-2)" "unprognostic (2.22e-8)" "unprognostic (3.81e-2)" "unprognostic (3.76e-2)" "unprognostic (2.29e-2)" "unprognostic (1.54e-2)" 0.2 0.1 18.8 2.2 17.5 1.0 0.4 16.5 16.5 0.9 7.2 0.7 0.4 0.3 6.7 2.6 4.5 1.6 1.7 16.2 26.5 0.1 0.2 1.7 0.4 24.3 22.8 0.5 2.7 0.3 0.8 0.7 19.0 0.6 1.0 4.2 0.7 0.1 0.0 0.6 0.4 0.1 19.8 0.4 4.9 0.8 20.1 0.3 4.6 0.0 0.8 2.7 0.5 20.1 5.2 42.1 18.4 14.5 3.9 5.0 5.1 23.2 15.9 5.2 11.8 4.7 17.7 9.7 29.5 80.8 27.6 6.7 10.0 19.8 21.7 18.5 2.1 6.9 37.7 10.7 59.6 18.1 6.3 11.9 84.2 14.6 64.6 7.6 65.1 9.6 9.5 24.4 27.3 3.7 2.5 1.7 3.6 25.1 11.9 2.8 6.1 11.5 3.1 20.1 7.6 1.5 10.1 2.9 35.4 3.9 4.4 38.1 95.2 6.7 18.8 10.2 18.3 20.5 10.3 9.7 11.4 9.7 138.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 18.8 17.5 16.5 16.5 16.2 26.5 24.3 22.8 19.0 19.8 20.1 20.1 0.5 0.0 8.4 368.6 2.5 4.6 7.5 8.8 1.8 7.3 2.2 1.3 5.4 1.5 8.1 0.0 2.1 3.6 28.5 7.9 0.0 4.4 3.2 3.2 2.3 27.8 27.0 0.8 12.5 25.1 0.7 5.7 65.2 18.3 4.5 1.0 2.9 0.4 0.6 1.7 7.3 19.8 22.4 0.3 63.5 0.8 2.5 18.3 5.4 148.9 51.7 47.9 0.0 12.1 8.6 30.4 1.5 2.2 4.1 58.5 0.4 0.1 7.3 2.0 0.0 2.1 4.0 1.1 0.7 1.9 3.1 1.1 0.9 7.0 4.2 37.6 SLC9A6 "KIAA0267, NHE6" ENSG00000198689 "Solute carrier family 9 member A6" Q92581 X 135973841-136047269 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.3;Horizontal cells: 48.8;Inhibitory neurons: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059445, HPA059590" Enhanced Supported Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 18: U-2197 - ECM organization" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA059445: AB_2684021, HPA059590: AB_2684075" "unprognostic (1.35e-1)" "unprognostic (8.28e-3)" "unprognostic (4.36e-1)" "unprognostic (4.93e-2)" "unprognostic (1.84e-1)" "unprognostic (1.19e-1)" "unprognostic (2.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.15e-1)" "unprognostic (2.72e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (7.07e-2)" "unprognostic (5.30e-2)" "unprognostic (1.75e-1)" "unprognostic (4.49e-2)" "unprognostic (5.06e-2)" 5.1 6.3 11.6 5.6 11.9 4.6 3.3 1.2 15.7 5.6 0.0 6.0 8.5 6.4 3.3 6.3 5.7 5.5 8.6 12.7 19.0 6.9 4.5 6.7 5.7 7.8 4.4 8.0 3.8 10.4 2.2 4.7 8.9 4.0 6.1 14.4 4.1 4.9 7.5 4.7 7.8 7.4 3.4 5.7 5.8 5.8 15.3 5.6 6.7 7.1 6.6 5.6 1.6 4.2 20.0 10.5 9.1 3.8 14.8 14.2 17.3 15.9 16.9 13.3 27.9 9.2 15.5 14.8 35.2 18.4 19.8 11.6 14.3 14.0 19.1 11.7 12.9 4.0 15.3 5.3 7.9 11.6 13.3 7.7 11.6 22.0 10.8 9.4 11.2 12.5 7.5 20.5 14.9 8.7 15.5 3.4 6.0 7.1 14.0 10.4 16.0 15.2 9.4 9.8 9.5 7.2 11.4 1.2 8.9 8.8 4.5 8.7 16.4 16.5 10.9 24.5 20.7 9.6 23.8 12.7 10.0 19.4 9.4 2.0 5.0 3.0 6.4 7.0 11.1 4.1 7.1 5.9 5.8 2.6 7.6 5.7 2.0 5.1 6.0 3.5 6.9 5.4 11.6 11.9 1.2 15.7 12.7 19.0 7.8 4.4 8.9 3.4 15.3 4.2 4.3 3.2 5.4 22.9 5.9 7.5 1.4 6.2 7.4 14.2 2.7 3.4 11.2 12.8 4.0 12.9 8.4 2.5 6.1 8.9 0.0 4.3 0.8 4.2 4.1 4.9 10.7 5.0 40.3 6.0 2.4 5.1 8.6 6.8 1.3 4.6 8.2 9.6 9.9 48.8 42.0 4.0 8.2 13.0 7.0 1.4 5.6 9.8 8.8 15.9 8.2 12.9 4.1 19.6 22.7 6.1 6.0 4.5 3.8 2.0 10.3 6.0 3.1 7.8 0.0 5.1 8.4 9.0 11.9 7.0 6.8 2.9 8.9 3.1 6.0 3.1 SLC9A7 NHE7 ENSG00000065923 "Solute carrier family 9 member A7" Q96T83 X 46599251-46759118 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Potassium transport, Sodium transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 41.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 43.3;Inhibitory neurons: 66.8;Oligodendrocyte precursor cells: 69.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048938, HPA075385" Approved Supported Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA048938: AB_2680565, HPA075385: AB_2686747" "unprognostic (2.77e-1)" "unprognostic (4.68e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (8.58e-4)" "prognostic unfavorable (8.14e-4)" "unprognostic (2.16e-2)" "unprognostic (2.73e-3)" "unprognostic (5.26e-3)" "unprognostic (1.28e-2)" "unprognostic (9.25e-2)" "unprognostic (5.30e-2)" "unprognostic (1.11e-1)" "unprognostic (2.08e-1)" "unprognostic (7.20e-2)" "unprognostic (2.62e-1)" "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" 0.5 5.0 9.1 2.4 41.6 3.6 5.8 6.3 14.6 1.2 0.5 0.6 1.2 0.8 2.6 1.9 1.7 1.6 1.1 8.6 17.0 2.6 3.1 1.3 6.3 13.9 7.5 4.3 3.4 8.9 9.2 1.1 14.2 4.6 0.9 4.9 6.0 2.0 5.7 2.1 2.2 0.7 6.7 3.7 6.3 0.8 14.5 3.2 4.3 2.5 6.3 1.8 1.3 5.1 10.4 7.7 1.1 3.3 1.2 7.4 4.3 9.6 12.0 5.7 4.5 7.9 10.9 22.7 2.9 15.6 11.0 4.6 7.4 10.9 10.3 11.9 3.9 2.3 3.1 3.3 4.6 1.0 17.9 4.6 1.4 16.1 10.6 26.8 8.2 7.7 0.2 0.3 7.9 15.7 2.6 1.2 5.3 5.0 9.2 10.0 0.4 0.2 4.4 11.4 8.2 1.0 4.9 7.3 2.1 9.2 9.7 0.4 0.4 12.0 4.0 1.8 5.7 2.3 0.5 11.2 17.1 0.1 4.0 0.5 0.2 0.1 0.1 0.2 0.1 1.7 0.2 0.1 1.1 1.7 0.1 0.1 0.8 0.5 0.2 2.8 0.3 0.2 9.1 41.6 6.3 14.6 8.6 17.0 13.9 7.5 14.2 6.7 14.5 5.1 0.5 3.2 8.2 11.4 21.0 0.6 10.1 0.9 1.2 13.0 16.9 8.6 5.7 1.5 2.6 16.5 4.2 7.9 24.4 0.3 0.0 17.6 0.0 1.8 2.0 1.5 2.4 5.5 43.3 14.2 0.7 2.7 13.3 1.7 0.0 4.5 0.7 6.5 6.4 13.5 66.8 2.0 0.0 6.3 8.4 0.6 0.9 9.2 1.8 3.7 8.0 6.1 1.0 69.9 1.6 16.4 0.1 0.4 2.8 21.0 0.1 2.1 0.1 3.5 6.6 12.1 1.9 0.0 1.6 4.2 1.0 7.3 2.9 1.3 0.9 11.5 SLITRK5 "bA364G4.2, KIAA0918, LRRC11" ENSG00000165300 "SLIT and NTRK like family member 5" O94991 13 87672615-87696272 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6;fallopian tube: 2.9;salivary gland: 3.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 9.7;Excitatory neurons: 20.4;Horizontal cells: 21.9;Inhibitory neurons: 13.3;Oligodendrocyte precursor cells: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.0;HeLa: 3.7;hTERT-RPE1: 3.2;U-138 MG: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013843, HPA073230" Uncertain Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA013843: AB_1857233, HPA073230: " "unprognostic (1.92e-1)" "unprognostic (1.01e-2)" "unprognostic (3.82e-1)" "unprognostic (7.11e-4)" "unprognostic (6.94e-2)" "unprognostic (8.57e-3)" "unprognostic (1.63e-1)" "unprognostic (8.58e-3)" "unprognostic (1.18e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-2)" "unprognostic (1.11e-1)" "unprognostic (2.10e-2)" "unprognostic (1.81e-2)" "unprognostic (2.82e-1)" "unprognostic (1.36e-2)" "unprognostic (1.60e-1)" 0.1 0.1 1.3 0.0 1.9 0.0 0.1 0.8 2.6 0.1 0.0 0.3 0.0 0.0 0.4 0.1 2.9 0.0 0.1 1.9 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.2 0.0 0.0 0.7 0.1 0.7 3.7 1.3 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.1 1.5 0.0 0.9 0.1 0.1 0.0 0.5 1.1 0.0 0.7 7.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.0 1.3 0.9 3.7 0.0 0.4 0.0 0.0 1.5 0.1 0.0 0.6 3.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.7 0.0 0.9 0.7 0.1 0.1 0.2 0.0 1.1 0.1 0.0 0.2 0.0 0.0 0.5 1.7 0.0 2.4 0.0 0.0 0.4 1.1 0.0 0.0 2.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.3 1.9 0.8 2.6 1.9 0.6 0.0 0.1 0.0 0.2 1.5 1.1 0.0 0.0 1.1 1.3 0.0 0.1 1.5 0.0 0.0 9.7 0.6 1.7 1.8 1.5 0.0 0.0 4.2 0.0 5.9 0.2 0.0 0.4 0.7 2.1 0.5 1.0 0.0 2.7 20.4 0.0 0.0 1.6 0.0 5.0 1.3 0.5 0.0 0.0 0.0 21.9 13.3 1.9 0.0 0.0 0.0 1.0 5.9 0.5 0.0 1.0 0.1 7.0 0.0 11.1 0.9 0.0 0.1 4.9 0.0 2.5 0.0 0.1 1.5 1.6 0.0 4.6 0.3 5.5 0.2 0.4 0.0 0.0 0.1 0.0 0.2 1.1 SMIM17 ENSG00000268182 "Small integral membrane protein 17" P0DL12 19 56643159-56657247 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 8.9" "Group enriched" "Detected in some" 5 "Excitatory neurons: 18.0;Inhibitory neurons: 32.7" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.0;HEK 293: 1.8;SCLC-21H: 1.7" "Low region specificity" "Detected in all" "HPA071857, HPA071861" Enhanced Approved Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA071857: AB_2686461, HPA071861: AB_2686462" "unprognostic (1.32e-1)" "unprognostic (2.82e-1)" "unprognostic (1.24e-1)" "unprognostic (5.67e-3)" "unprognostic (1.62e-1)" "unprognostic (4.57e-2)" "unprognostic (5.84e-2)" "unprognostic (3.00e-2)" "unprognostic (2.51e-1)" "unprognostic (6.50e-2)" "unprognostic (4.64e-2)" "unprognostic (9.02e-3)" "unprognostic (3.46e-3)" "unprognostic (6.26e-2)" "unprognostic (1.01e-1)" "unprognostic (3.71e-3)" "unprognostic (7.51e-3)" 0.4 0.3 6.0 0.2 4.9 0.2 0.6 3.7 8.9 0.4 0.0 0.7 0.3 0.6 1.3 0.3 0.5 0.2 0.4 6.4 8.9 0.3 0.2 0.3 0.2 6.9 6.7 0.5 0.3 0.1 1.6 0.2 8.2 0.4 0.3 2.7 0.4 1.0 0.5 0.7 0.2 0.4 3.3 0.3 0.3 0.4 7.5 0.3 0.3 0.2 0.2 0.4 0.3 2.8 0.1 0.0 2.0 0.5 0.3 0.2 0.5 0.2 0.1 0.4 0.1 0.0 0.1 0.2 0.3 0.2 0.2 0.1 0.3 0.3 0.2 0.1 1.8 1.1 0.4 0.4 0.3 1.0 0.3 0.3 0.3 0.1 0.3 0.3 0.2 1.1 0.1 0.0 0.5 0.0 1.3 0.3 0.1 0.0 0.3 0.7 1.2 0.1 0.1 0.0 1.7 0.3 0.6 0.1 0.3 0.3 0.0 0.4 0.4 0.6 0.1 0.2 0.1 0.1 0.3 0.5 0.3 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 4.9 3.7 8.9 6.4 8.9 6.9 6.7 8.2 3.3 7.5 2.8 0.3 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.4 0.0 3.5 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SMIM3 "C5orf62, MSTP150, NID67" ENSG00000256235 "Small integral membrane protein 3" Q9BZL3 5 150778757-150796734 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 161.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 85.5;Basal squamous epithelial cells: 80.8;granulocytes: 90.0;Macrophages: 79.3;Sertoli cells: 138.1;Smooth muscle cells: 77.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 409.9;ASC TERT1: 200.1;LHCN-M2: 193.8;U-87 MG: 291.5" "Low region specificity" "Detected in all" HPA075345 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA075345: AB_2686744" "unprognostic (2.33e-1)" "unprognostic (4.05e-2)" "unprognostic (1.35e-2)" "unprognostic (2.70e-2)" "unprognostic (9.45e-2)" "unprognostic (5.65e-2)" "unprognostic (4.57e-3)" "unprognostic (1.47e-1)" "unprognostic (3.90e-1)" "unprognostic (2.05e-2)" "unprognostic (9.71e-3)" "unprognostic (3.46e-3)" "prognostic unfavorable (1.15e-8)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "unprognostic (2.16e-1)" "unprognostic (1.46e-3)" 161.0 36.2 20.5 25.5 20.3 89.5 71.5 20.9 26.4 21.9 42.1 26.8 13.4 16.2 22.6 16.8 30.2 25.7 36.8 20.5 22.1 34.9 12.2 30.9 11.7 23.3 21.5 25.9 33.7 26.9 15.1 46.0 23.6 27.6 19.1 20.4 14.0 24.1 15.0 12.5 23.0 28.3 20.7 25.2 21.6 4.1 23.5 17.7 21.0 15.5 8.8 29.0 18.7 19.6 13.8 4.5 7.3 60.8 409.9 200.1 15.9 52.3 114.6 19.2 77.2 21.5 35.3 0.0 3.1 55.1 12.7 10.7 12.5 11.8 28.6 0.2 3.8 20.0 2.8 9.9 72.4 19.7 130.0 167.9 23.6 54.2 25.1 122.3 6.4 46.6 5.5 0.4 193.8 10.5 28.5 27.0 3.8 10.7 12.5 15.2 1.2 0.0 20.6 10.2 1.8 4.7 7.8 1.1 16.1 8.1 25.4 120.6 10.1 84.2 15.2 65.9 27.5 0.0 0.4 0.2 291.5 75.0 10.8 68.7 41.0 72.4 20.8 17.2 12.7 1.3 14.5 14.4 19.4 0.2 14.1 12.1 42.7 13.0 16.2 57.3 2.3 38.0 20.5 20.3 20.9 26.4 20.5 22.1 23.3 21.5 23.6 20.7 23.5 19.6 53.7 6.4 8.6 2.6 3.2 0.0 85.5 0.0 80.8 0.8 12.0 16.6 9.9 7.2 2.5 7.3 0.0 8.5 22.8 4.0 13.7 6.4 0.8 1.3 11.1 25.4 4.8 8.4 1.0 31.3 5.0 53.5 2.6 1.1 90.0 1.7 13.2 1.0 45.2 0.0 2.0 36.8 0.0 34.2 0.0 0.6 14.0 79.3 0.0 16.9 30.2 62.1 11.3 5.5 0.1 18.2 1.1 36.9 3.5 15.9 3.9 8.8 0.0 1.9 138.1 72.3 77.2 0.1 0.5 20.1 0.0 8.1 28.8 3.0 7.4 40.1 SMIM8 "C6orf162, dJ102H19.2, DKFZP586E1923" ENSG00000111850 "Small integral membrane protein 8" Q96KF7 6 87322583-87399749 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007401, HPA067453" Approved Approved Vesicles NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA007401: AB_1078357, HPA067453: AB_2685844" "unprognostic (2.54e-1)" "unprognostic (5.24e-2)" "unprognostic (1.19e-1)" "unprognostic (1.90e-1)" "unprognostic (1.56e-2)" "unprognostic (3.16e-2)" "unprognostic (3.09e-2)" "unprognostic (6.17e-2)" "unprognostic (5.31e-2)" "unprognostic (6.12e-3)" "unprognostic (1.86e-5)" "unprognostic (1.98e-1)" "unprognostic (1.34e-1)" "unprognostic (2.01e-1)" "unprognostic (3.06e-2)" "unprognostic (2.86e-2)" "unprognostic (4.01e-1)" 5.0 5.0 8.0 3.8 8.0 6.0 5.2 8.5 9.5 6.4 8.1 6.0 5.2 6.5 6.7 4.1 5.5 2.7 7.7 8.1 8.3 7.3 7.0 3.9 5.0 7.8 8.0 6.5 4.7 6.2 7.2 3.4 7.8 4.7 4.6 8.7 4.0 3.9 10.6 4.3 4.8 4.1 8.1 4.1 4.1 4.9 8.5 6.7 4.8 8.7 4.0 5.3 5.5 8.0 5.3 4.6 9.3 16.2 5.3 6.0 4.1 5.8 4.5 4.8 9.2 3.2 4.8 10.8 6.8 5.8 8.4 6.5 7.6 4.4 9.1 9.6 8.2 15.9 5.2 6.4 5.0 16.8 5.5 5.7 5.9 4.9 5.2 5.4 7.0 13.8 18.1 17.7 5.5 4.0 10.1 13.3 5.7 7.9 7.1 16.1 13.8 6.2 6.2 5.2 15.9 6.5 8.5 5.0 10.1 8.4 4.6 16.5 6.8 2.5 7.2 10.8 5.7 7.8 13.6 7.2 8.1 7.9 7.6 5.8 8.8 15.7 11.2 8.6 11.4 18.5 13.2 13.6 10.1 11.4 19.3 16.9 14.7 9.7 10.3 8.5 18.4 9.1 8.0 8.0 8.5 9.5 8.1 8.3 7.8 8.0 7.8 8.1 8.5 8.0 19.4 12.8 5.8 18.9 17.6 13.8 20.6 29.7 8.6 24.4 12.8 16.0 47.3 17.2 16.6 23.9 37.5 17.7 8.7 8.0 45.0 10.7 18.7 32.1 19.0 15.0 8.5 17.1 21.7 10.3 12.3 17.8 12.8 9.6 5.1 31.4 22.5 13.8 14.9 37.0 19.8 9.4 36.7 12.3 11.5 14.5 15.8 11.1 8.8 8.4 11.0 28.4 13.4 8.0 13.3 8.1 11.6 20.7 14.0 10.1 15.5 23.0 17.5 22.9 26.3 21.1 17.9 23.9 28.4 10.7 14.8 14.9 14.8 30.7 16.5 13.4 SMU1 "BWD, FLJ10805, fSAP57, SMU-1" ENSG00000122692 "SMU1 DNA replication regulator and spliceosomal factor" Q2TAY7 9 33041765-33076674 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019708 Supported Approved Vesicles NA NA 25000 "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA019708: AB_1857300" "unprognostic (2.20e-2)" "prognostic favorable (2.66e-4)" "unprognostic (1.17e-1)" "unprognostic (1.58e-1)" "unprognostic (1.80e-2)" "unprognostic (8.44e-2)" "unprognostic (2.59e-3)" "unprognostic (5.06e-2)" "unprognostic (3.04e-2)" "prognostic favorable (1.25e-4)" "unprognostic (4.98e-3)" "unprognostic (3.15e-1)" "prognostic favorable (1.67e-5)" "unprognostic (1.09e-2)" "unprognostic (7.04e-2)" "unprognostic (8.71e-2)" "unprognostic (5.96e-2)" 11.5 11.3 11.2 10.6 13.0 16.0 11.9 13.9 12.1 11.4 8.6 10.9 8.6 13.1 11.8 10.6 11.4 8.6 10.3 10.7 11.5 11.2 12.9 10.0 12.8 12.4 11.9 14.7 8.2 15.8 8.1 8.4 12.4 11.9 10.9 12.6 9.3 11.5 14.4 12.8 9.4 13.2 12.6 12.1 9.1 8.5 11.7 14.1 11.2 13.0 15.2 11.5 9.9 16.6 26.3 20.4 24.0 20.9 25.4 19.3 18.7 20.1 18.1 26.9 26.5 20.8 10.7 33.0 14.4 25.1 14.6 15.7 31.1 24.1 29.7 38.1 14.9 24.8 33.4 24.5 22.1 43.5 22.4 20.4 27.0 24.9 17.6 20.1 22.9 22.7 23.4 20.5 22.7 12.1 34.2 46.3 33.1 19.6 21.4 28.8 19.9 17.9 20.5 19.4 20.3 17.7 27.2 19.4 13.1 18.6 18.7 15.7 24.6 17.2 19.1 25.2 23.8 9.1 18.1 38.0 19.2 20.2 12.5 23.4 13.9 11.5 12.4 15.4 13.3 12.9 14.0 11.6 15.8 11.7 13.9 14.3 8.1 12.4 17.9 20.0 12.6 10.8 11.2 13.0 13.9 12.1 10.7 11.5 12.4 11.9 12.4 12.6 11.7 16.6 45.5 25.6 31.4 17.9 48.0 53.7 45.7 41.0 43.3 29.5 23.8 22.4 30.6 30.0 39.9 20.2 37.5 34.9 72.7 19.1 21.5 32.3 29.6 41.6 42.8 38.2 28.1 24.4 23.4 24.3 36.3 37.7 17.9 47.3 39.2 32.1 21.4 29.4 30.8 23.5 25.3 19.5 44.7 29.2 40.8 8.7 32.3 40.2 23.2 14.0 39.7 34.8 32.0 21.6 28.3 27.9 20.1 25.9 28.3 33.3 18.1 31.7 44.1 39.3 19.7 53.9 44.7 41.4 30.5 36.3 57.5 57.7 43.7 37.0 23.5 35.5 SNX16 ENSG00000104497 "Sorting nexin 16" P57768 8 81799581-81842866 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 82.8;Late spermatids: 137.3;Spermatocytes: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024730, HPA024731, HPA024817" Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA024730: AB_10600220, HPA024731: AB_1857346, HPA024817: AB_10602313" "unprognostic (5.50e-2)" "unprognostic (3.20e-2)" "unprognostic (1.40e-1)" "unprognostic (8.41e-3)" "unprognostic (3.21e-3)" "unprognostic (7.54e-3)" "unprognostic (1.24e-3)" "unprognostic (1.33e-1)" "unprognostic (2.12e-1)" "unprognostic (2.18e-1)" "unprognostic (3.94e-2)" "unprognostic (1.43e-1)" "unprognostic (5.73e-3)" "unprognostic (7.60e-3)" "unprognostic (2.30e-1)" "unprognostic (1.35e-1)" "unprognostic (3.65e-1)" 10.1 5.2 4.7 6.0 5.7 10.7 8.2 6.6 7.6 8.6 2.5 6.3 6.4 9.7 8.3 17.3 6.2 10.8 8.1 5.3 6.6 6.6 5.5 6.7 5.1 6.1 7.4 9.6 3.1 8.9 3.7 5.5 8.6 7.3 6.6 4.9 5.7 7.7 4.6 11.2 5.7 11.9 5.8 12.0 9.0 14.9 5.7 9.4 8.7 9.4 6.7 7.0 7.7 6.7 13.8 3.8 6.6 6.3 22.9 13.7 7.3 16.6 20.2 14.1 20.6 3.4 11.1 2.2 10.0 11.4 16.5 11.0 5.1 6.8 19.5 19.9 3.1 7.1 5.2 6.2 17.4 2.9 11.5 10.5 10.6 5.4 12.5 15.8 10.0 7.8 4.5 26.0 32.9 7.2 15.6 5.1 2.8 12.6 6.2 6.6 9.5 2.4 12.7 6.7 10.9 8.3 3.1 3.9 8.3 9.8 10.3 5.5 7.7 19.5 15.6 13.5 7.2 15.1 12.5 5.7 8.4 9.1 15.7 9.2 4.5 6.1 2.1 2.8 2.0 1.6 2.5 1.7 4.0 4.4 2.9 2.8 6.2 2.6 2.4 3.0 5.0 1.9 4.7 5.7 6.6 7.6 5.3 6.6 6.1 7.4 8.6 5.8 5.7 6.7 10.6 6.4 9.4 9.8 6.4 25.2 12.1 5.0 9.6 5.5 12.1 7.6 8.8 7.2 9.3 5.5 4.2 2.3 3.7 7.5 5.9 5.9 82.8 9.4 7.8 11.5 3.0 8.2 24.7 6.0 4.0 8.5 10.7 16.2 8.2 5.0 13.9 3.5 5.7 55.5 18.4 6.2 8.2 7.0 10.0 137.3 23.3 7.2 3.6 8.4 2.3 4.3 1.0 23.1 22.2 6.7 5.5 16.1 8.6 12.6 3.7 7.3 10.9 5.2 19.7 12.1 9.3 74.2 26.5 13.0 32.0 9.9 5.4 4.2 4.7 20.7 SNX24 SBBI31 ENSG00000064652 "Sorting nexin 24" Q9Y343 5 122843439-123029354 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044566, HPA073934" Approved Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA044566: AB_10797034, HPA073934: AB_2686644" "unprognostic (2.63e-1)" "unprognostic (2.50e-1)" "unprognostic (2.73e-1)" "prognostic unfavorable (7.93e-6)" "unprognostic (2.31e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (8.88e-4)" "unprognostic (1.37e-1)" "unprognostic (1.61e-1)" "unprognostic (3.42e-1)" "unprognostic (5.77e-2)" "unprognostic (3.69e-2)" "prognostic favorable (1.28e-4)" "unprognostic (2.03e-1)" "unprognostic (1.10e-1)" "unprognostic (6.94e-2)" "unprognostic (1.50e-2)" 8.1 8.1 12.3 5.5 15.1 4.5 7.5 19.0 15.5 9.5 13.1 11.1 15.2 6.5 11.8 36.8 7.6 10.5 12.3 11.4 15.6 20.6 14.1 17.3 6.5 19.3 15.6 5.9 10.6 25.6 7.8 25.3 18.6 6.1 12.5 12.5 12.3 6.5 9.5 16.8 11.5 11.0 16.9 7.7 16.4 8.7 17.1 2.5 18.5 14.0 8.8 9.2 14.2 23.9 33.2 14.7 23.5 15.8 8.5 21.7 47.2 28.7 26.7 32.9 42.1 20.8 30.0 0.0 24.0 28.3 31.9 6.7 15.2 36.8 50.3 17.8 9.3 4.7 13.4 29.8 43.4 0.2 5.4 18.3 53.4 16.6 64.4 28.5 16.0 5.7 6.1 26.3 25.1 29.5 0.8 1.3 9.6 6.0 9.3 4.2 37.3 16.3 47.8 19.8 14.4 17.2 27.1 19.7 31.2 30.4 35.5 10.4 13.9 35.4 27.3 14.0 46.6 9.1 12.9 5.0 30.3 0.6 73.4 0.0 1.4 0.0 0.6 2.8 0.3 0.3 0.6 0.5 0.7 0.2 0.2 0.1 0.0 1.3 3.2 0.1 1.4 0.5 12.3 15.1 19.0 15.5 11.4 15.6 19.3 15.6 18.6 16.9 17.1 23.9 7.8 44.8 24.6 45.4 1.1 10.5 7.5 10.6 3.4 18.3 8.7 5.8 14.9 14.3 6.3 20.2 6.2 45.1 3.7 17.7 35.2 15.6 75.8 18.6 11.1 6.5 1.2 4.0 51.8 11.8 57.1 12.6 7.1 15.0 0.0 19.1 8.6 12.9 66.1 11.8 52.1 6.7 6.1 51.9 4.7 95.9 9.0 21.0 3.6 60.9 16.0 12.4 4.1 46.8 63.5 21.9 4.4 9.4 2.7 16.2 35.2 39.9 12.0 18.0 13.1 7.0 9.1 5.0 9.6 19.5 16.8 39.7 3.9 39.2 8.9 11.8 SNX25 SBBI31 ENSG00000109762 "Sorting nexin 25" Q9H3E2 4 185204237-185370185 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 128.9;Astrocytes: 50.6;Excitatory neurons: 57.7;Inhibitory neurons: 60.7;Oligodendrocyte precursor cells: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "HDLM-2: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036928 Supported Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA036928: AB_10669720" "unprognostic (9.20e-2)" "unprognostic (1.31e-1)" "unprognostic (2.26e-1)" "unprognostic (4.29e-3)" "unprognostic (8.89e-2)" "unprognostic (5.63e-2)" "unprognostic (1.43e-2)" "unprognostic (6.41e-2)" "unprognostic (5.35e-2)" "unprognostic (2.99e-2)" "unprognostic (4.03e-3)" "unprognostic (1.87e-1)" "unprognostic (3.33e-1)" "unprognostic (1.13e-1)" "unprognostic (1.57e-1)" "unprognostic (1.32e-2)" "unprognostic (8.55e-3)" 7.6 8.0 7.0 7.3 8.4 2.0 9.5 17.3 7.9 6.0 23.9 12.3 3.5 6.9 6.3 7.1 9.7 8.5 8.7 7.5 8.9 11.3 9.1 29.1 11.5 9.6 10.0 7.4 10.0 13.3 10.5 11.8 9.7 14.9 6.7 25.5 6.7 8.6 10.2 6.2 7.9 7.0 8.1 9.5 6.2 12.7 8.8 2.9 16.7 8.6 12.9 7.2 5.4 7.3 11.9 6.2 7.8 11.0 20.5 15.0 11.5 35.6 17.1 17.9 14.9 5.3 8.1 33.6 3.8 26.0 12.4 4.6 8.9 7.8 20.0 55.9 14.5 5.7 7.5 12.8 11.9 3.8 8.0 10.4 8.3 15.6 8.6 36.0 15.7 6.3 12.0 33.3 23.9 3.5 1.5 6.9 6.3 1.6 5.9 4.9 9.0 8.6 43.0 4.5 16.5 11.9 7.4 2.0 30.3 10.8 4.2 4.9 30.0 10.2 6.5 9.8 15.7 29.3 12.8 7.1 16.7 2.8 12.9 0.0 0.0 0.0 0.1 0.0 0.3 0.7 0.3 0.4 0.0 1.0 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.0 7.0 8.4 17.3 7.9 7.5 8.9 9.6 10.0 9.7 8.1 8.8 7.3 9.5 25.6 128.9 50.6 12.6 4.8 4.2 2.3 4.6 15.9 7.0 3.4 6.8 0.0 7.3 5.5 31.3 4.8 5.5 5.4 0.0 4.8 5.9 11.5 8.1 9.6 0.0 0.0 57.7 2.6 4.9 4.9 5.1 10.3 1.3 3.9 12.5 8.8 2.0 6.7 60.7 4.0 2.0 3.2 2.5 4.8 9.6 2.2 21.4 32.8 0.6 5.6 3.1 55.3 21.4 3.9 1.6 9.8 11.3 9.4 5.6 2.3 6.7 15.7 0.0 4.8 5.7 9.0 16.2 2.3 6.1 5.6 7.0 10.3 3.3 5.5 SNX27 "KIAA0488, MGC20471, MY014" ENSG00000143376 "Sorting nexin 27" Q96L92 1 151612006-151699091 "Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 21.4;classical monocyte: 35.8;intermediate monocyte: 30.8;myeloid DC: 16.3;neutrophil: 40.4;non-classical monocyte: 35.4" "Group enriched" "Detected in all" 5 "dendritic cells: 16.3;granulocytes: 40.4;monocytes: 35.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028551 Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA028551: " "unprognostic (3.35e-1)" "unprognostic (4.76e-1)" "unprognostic (1.38e-1)" "unprognostic (2.13e-2)" "unprognostic (2.79e-2)" "unprognostic (3.42e-1)" "unprognostic (2.41e-2)" "unprognostic (1.48e-2)" "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (5.92e-2)" "unprognostic (1.63e-1)" "unprognostic (5.45e-2)" "unprognostic (2.81e-1)" "unprognostic (4.15e-1)" "unprognostic (7.30e-2)" "unprognostic (1.04e-1)" 7.6 8.6 18.1 7.7 24.7 8.7 7.2 20.2 21.1 9.1 9.2 14.4 5.3 9.1 9.2 7.5 8.6 6.7 8.8 17.1 23.2 14.5 8.5 8.9 6.8 21.5 21.5 9.7 6.9 11.8 10.2 10.7 21.8 9.5 7.4 15.9 7.2 11.6 17.6 9.6 8.3 10.0 20.5 11.2 8.5 7.9 20.1 7.2 7.4 21.3 6.5 12.4 8.2 22.3 9.7 14.2 14.7 18.6 22.9 16.8 32.7 5.1 10.5 8.9 9.5 11.6 12.5 9.1 10.9 8.3 9.5 11.7 19.1 10.4 11.0 13.1 6.9 14.7 8.4 13.1 15.1 17.8 9.6 13.4 7.7 10.2 11.6 9.0 10.1 14.3 9.0 54.8 11.8 17.3 10.6 12.2 26.1 19.0 9.0 10.8 14.3 11.8 13.9 14.3 14.7 12.6 13.8 25.4 10.1 15.8 16.3 14.9 13.4 12.5 8.2 13.1 10.9 11.4 12.2 17.8 14.8 11.2 14.2 21.4 35.8 5.4 4.6 30.8 6.6 3.2 5.8 4.2 16.3 4.4 5.5 4.6 40.4 3.5 35.4 4.2 5.1 17.3 18.1 24.7 20.2 21.1 17.1 23.2 21.5 21.5 21.8 20.5 20.1 22.3 18.4 12.8 27.1 24.8 17.9 21.2 15.5 14.6 13.1 45.8 21.6 13.7 29.9 20.0 17.3 29.5 27.1 56.0 20.4 13.8 25.4 25.7 32.6 18.5 28.0 19.7 18.7 10.8 58.3 20.9 22.4 25.4 14.3 22.7 3.8 20.8 25.7 19.4 43.3 40.4 77.6 12.8 20.3 85.4 21.3 10.4 30.4 51.9 30.2 40.3 71.4 24.6 11.3 45.2 60.0 26.9 10.5 39.9 16.4 16.2 19.6 57.7 13.7 26.6 32.9 27.6 27.0 53.3 28.8 17.0 24.7 104.8 19.4 33.8 15.3 17.9 SNX8 Mvp1 ENSG00000106266 "Sorting nexin 8" Q9Y5X2 7 2251770-2354318 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 108.9;Late spermatids: 358.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 100.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057296, HPA060194" Approved Supported Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA057296: AB_2683401, HPA060194: AB_2684219" "unprognostic (2.22e-2)" "unprognostic (3.38e-1)" "unprognostic (9.85e-3)" "unprognostic (1.39e-1)" "unprognostic (2.08e-2)" "unprognostic (9.32e-2)" "prognostic unfavorable (8.47e-6)" "unprognostic (5.23e-2)" "unprognostic (1.91e-3)" "unprognostic (1.54e-2)" "unprognostic (3.06e-1)" "unprognostic (6.01e-2)" "unprognostic (1.54e-1)" "unprognostic (5.10e-2)" "unprognostic (4.83e-2)" "unprognostic (1.12e-2)" "unprognostic (1.35e-1)" 15.4 6.8 13.7 11.3 14.1 10.9 12.4 11.8 11.4 7.0 10.9 7.7 10.6 6.9 3.1 10.2 7.0 9.8 12.8 12.9 11.3 7.3 7.2 9.7 21.5 15.1 13.0 7.5 7.5 5.9 5.4 9.3 13.3 4.3 6.8 5.7 7.8 3.0 11.0 10.2 9.5 5.6 12.9 32.7 6.9 23.2 15.1 7.9 8.3 7.5 17.7 8.5 5.7 14.9 40.3 38.7 15.6 21.8 21.3 20.5 36.7 19.2 28.4 31.8 39.2 27.3 30.6 23.4 7.7 22.8 100.9 10.6 13.6 10.5 16.1 5.9 12.8 13.0 15.5 22.9 53.9 12.7 20.8 41.4 12.1 39.0 15.0 8.5 12.1 18.3 26.0 26.9 26.4 26.4 4.3 13.5 28.4 22.4 19.0 20.6 32.2 10.7 7.5 18.8 7.5 19.7 17.4 47.8 27.3 17.0 35.5 27.4 18.5 26.6 69.7 44.0 25.4 17.5 22.9 21.9 26.4 16.9 73.6 11.8 15.4 5.1 2.9 17.2 2.1 26.1 2.1 2.9 21.8 30.6 2.0 2.4 2.6 2.2 17.8 5.4 3.4 8.7 13.7 14.1 11.8 11.4 12.9 11.3 15.1 13.0 13.3 12.9 15.1 14.9 7.4 6.4 9.4 3.9 35.7 5.2 7.8 6.1 2.8 10.0 12.3 10.4 12.4 10.0 4.8 3.7 8.4 16.7 7.7 10.5 13.7 21.0 108.9 3.3 12.8 13.0 6.0 26.3 5.0 30.0 15.4 10.3 10.7 4.5 12.6 8.2 45.3 8.8 78.1 21.9 7.8 10.9 6.1 35.2 75.2 358.9 12.2 36.7 14.2 6.5 41.9 7.8 7.2 2.5 9.1 26.9 7.9 13.2 12.9 8.8 12.5 14.9 5.5 12.5 0.0 5.3 9.6 10.6 22.9 5.7 6.1 43.4 6.3 29.6 9.7 9.2 SOHLH2 "bHLHe81, FLJ20449, SPATA28, TEB1" ENSG00000120669 "Spermatogenesis and oogenesis specific basic helix-loop-helix 2" Q9NX45 13 36168217-36214588 "Predicted intracellular proteins, Transcription factors" "Differentiation, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 27.5" "Group enriched" "Detected in some" 5 "Early spermatids: 55.5;Extravillous trophoblasts: 19.5;Late spermatids: 77.0;Spermatocytes: 22.5;Spermatogonia: 33.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 8.3;HL-60: 11.2;Karpas-707: 12.1;NB-4: 16.1;U-266/84: 16.5" HPA029182 Uncertain Vesicles NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Vesicles "HPA029182: AB_10602409" "unprognostic (1.00e-1)" "unprognostic (1.65e-1)" "unprognostic (1.99e-1)" "unprognostic (2.99e-2)" "unprognostic (2.54e-2)" "unprognostic (3.01e-2)" "unprognostic (2.95e-1)" "unprognostic (7.88e-2)" "unprognostic (2.12e-1)" "unprognostic (1.39e-1)" "unprognostic (5.53e-3)" "unprognostic (2.10e-1)" "unprognostic (8.56e-2)" "unprognostic (7.44e-2)" "unprognostic (5.93e-2)" 0.5 0.4 0.9 0.1 0.9 0.8 0.5 0.5 1.1 0.3 0.2 2.0 0.3 0.4 2.1 0.4 0.3 0.3 1.0 0.9 1.9 0.7 0.0 0.1 0.3 0.8 0.7 0.3 0.0 1.4 0.3 1.1 0.7 1.8 0.1 1.2 0.2 1.3 0.6 0.3 0.2 0.5 0.8 0.1 0.3 27.5 1.1 0.3 0.5 5.3 0.0 0.9 0.1 1.1 8.3 0.2 0.8 0.0 0.7 1.3 4.8 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.5 0.2 0.2 0.0 0.1 0.0 0.1 1.9 0.1 0.0 0.1 11.2 0.0 2.2 0.6 0.0 0.0 0.4 1.0 0.3 0.4 12.1 2.5 0.1 0.0 16.1 0.2 0.0 0.0 0.2 0.2 0.9 1.2 0.8 0.2 1.5 0.0 0.0 0.0 2.9 0.1 0.7 0.0 0.0 0.9 0.6 0.5 1.6 16.5 0.2 0.9 5.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.5 1.1 0.9 1.9 0.8 0.7 0.7 0.8 1.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.7 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 55.5 0.1 0.2 0.1 0.0 0.0 0.0 0.0 19.5 0.1 0.0 0.3 0.0 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 77.0 0.6 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 2.1 0.0 0.3 0.0 0.0 0.1 22.5 33.5 0.0 0.1 3.4 0.0 0.1 0.0 0.1 SPA17 "CT22, SP17" ENSG00000064199 "Sperm autoantigenic protein 17" Q15506 11 124673844-124697518 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 231.3" "Cell type enhanced" "Detected in many" "Early spermatids: 1583.7;Endometrial ciliated cells: 371.2;Late spermatids: 2667.9;Respiratory ciliated cells: 368.6;Spermatocytes: 580.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037568 Enhanced Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 6: T47d - Mammary gland" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA037568: AB_10672905" "unprognostic (1.41e-2)" "unprognostic (3.49e-1)" "unprognostic (2.39e-3)" "prognostic favorable (1.03e-4)" "unprognostic (2.85e-1)" "unprognostic (1.56e-1)" "unprognostic (1.01e-4)" "unprognostic (2.64e-1)" "unprognostic (3.80e-2)" "unprognostic (4.56e-2)" "unprognostic (6.47e-2)" "unprognostic (8.54e-2)" "unprognostic (1.71e-3)" "unprognostic (6.78e-2)" "unprognostic (9.78e-3)" "unprognostic (8.52e-2)" "unprognostic (2.71e-1)" 3.2 4.2 2.6 1.1 2.8 1.6 3.8 2.4 2.6 4.4 9.0 5.4 1.4 4.4 10.5 5.0 24.5 2.3 4.5 2.8 3.1 11.6 2.1 7.7 1.0 4.6 4.9 1.6 4.3 4.7 13.5 0.9 4.1 4.3 3.2 1.0 3.5 2.1 1.2 2.6 3.0 1.6 3.8 1.8 4.0 231.3 3.3 2.6 8.9 0.2 1.4 3.2 3.0 3.3 4.1 5.4 12.6 4.3 4.2 6.4 4.7 3.8 8.4 5.4 4.4 1.4 11.5 2.8 2.2 6.7 4.3 3.4 4.9 8.0 7.3 2.6 3.6 3.6 0.8 2.4 2.3 1.0 1.6 2.6 4.8 7.9 4.1 4.2 4.5 5.7 5.5 2.2 12.4 5.5 0.5 0.2 4.7 8.3 4.3 3.8 1.5 0.1 12.8 3.1 6.6 5.8 9.1 2.7 1.8 4.6 17.1 3.1 3.2 4.8 3.8 2.8 4.5 1.4 0.9 1.1 5.0 0.9 5.1 0.5 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.6 0.1 0.0 0.2 2.6 2.8 2.4 2.6 2.8 3.1 4.6 4.9 4.1 3.8 3.3 3.3 5.9 3.2 12.6 3.6 0.9 2.7 4.7 26.9 1.8 2.6 6.2 6.5 2.1 17.2 54.2 20.2 4.2 6.7 2.3 13.0 19.6 29.2 1583.7 371.2 13.8 7.2 7.2 3.2 5.8 15.5 10.8 5.8 8.2 19.4 0.0 7.1 1.8 1.5 11.9 0.0 2.8 9.2 32.6 3.1 1.0 2667.9 28.0 6.6 1.8 1.9 2.6 8.1 0.0 1.0 0.7 12.7 10.0 18.0 1.4 2.9 6.3 47.0 368.6 1.2 13.1 6.2 10.5 580.0 63.6 4.9 2.3 2.7 2.6 8.4 10.4 5.6 SPARC "BM-40, ON, ONT" ENSG00000113140 "Secreted protein acidic and cysteine rich" P09486 5 151661096-151686975 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 2184.6" "Cell type enhanced" "Detected in many" "Adipocytes: 737.1;Endometrial stromal cells: 1209.0;Endothelial cells: 781.9;Fibroblasts: 1032.1;Peritubular cells: 1111.1;Sertoli cells: 2353.5;Smooth muscle cells: 1527.3;Theca cells: 987.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.4;classical monocyte: 8.7;neutrophil: 24.3" "Group enriched" "Detected in many" 7 "granulocytes: 24.3;monocytes: 8.7" "Cell line enhanced" "Detected in many" "ASC diff: 4911.5;BJ: 4101.8;fHDF/TERT166: 6492.5;WM-115: 4789.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002306, HPA002989, HPA003020" Supported Approved Vesicles "Secreted to blood" NA NA 8300000 130000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB002306: AB_563919, HPA002989: AB_1079532, HPA003020: AB_1079531" "unprognostic (3.34e-2)" "unprognostic (8.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.97e-1)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (8.36e-3)" "unprognostic (5.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.09e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.53e-5)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.53e-1)" "unprognostic (4.93e-3)" 1661.2 406.4 578.0 436.4 922.0 32.4 528.6 733.1 339.2 837.2 297.8 355.6 110.5 538.9 112.7 307.7 271.4 1526.8 563.5 362.9 1554.2 176.1 158.5 498.0 232.1 1370.4 1251.5 348.2 119.2 273.1 111.4 2184.6 1224.8 227.1 185.2 36.4 113.1 378.0 258.2 286.1 157.4 1251.5 995.9 260.8 143.3 406.7 1135.4 70.9 294.1 473.5 131.6 829.5 249.0 1088.4 5.9 5.0 1196.5 57.5 4911.5 1596.0 112.6 4101.8 1336.6 1649.3 1693.8 5.5 4.2 2.0 953.7 6492.5 272.0 56.7 153.4 316.2 555.0 4.8 57.1 56.7 0.4 116.8 1441.6 2.9 5.4 2567.2 436.9 1233.8 170.8 1903.1 2315.1 13.5 53.7 44.6 944.1 0.4 4.7 35.5 556.2 0.4 4.4 2.9 1192.9 4.3 0.5 0.5 45.5 88.4 2.8 1.4 534.9 1922.1 4.7 138.2 2759.9 771.0 1195.2 350.2 1304.4 3.7 6.0 7.6 648.4 3.7 4789.0 10.4 8.7 2.7 1.0 0.3 0.0 0.1 0.0 0.1 2.3 0.2 0.3 0.0 24.3 0.0 0.1 1.9 0.0 123.9 578.0 922.0 733.1 339.2 362.9 1554.2 1370.4 1251.5 1224.8 995.9 1135.4 1088.4 737.1 83.3 27.5 7.2 6.8 164.8 25.7 23.8 28.5 85.7 11.2 100.5 43.6 5.7 18.8 16.5 2.1 115.4 2.8 0.1 0.0 4.6 14.2 41.6 1209.0 781.9 0.0 15.1 4.3 0.4 354.3 1032.1 9.7 31.5 12.0 146.5 668.6 9.9 108.2 1.7 2.9 0.0 0.0 50.0 175.7 46.8 319.3 92.0 234.7 38.4 10.7 13.6 3.1 21.6 37.3 5.5 0.0 1111.1 4.1 7.7 0.0 42.0 7.8 72.7 2353.5 510.4 1527.3 14.2 10.9 4.8 108.3 147.4 21.1 987.4 0.0 5.3 SPEG "APEG1, BPEG, KIAA1297, MGC12676, MYLK6, SPEGalpha, SPEGbeta" ENSG00000072195 "Striated muscle enriched protein kinase" Q15772 2 219434843-219493629 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 174.8" "Cell type enhanced" "Detected in many" "Astrocytes: 45.7;Cardiomyocytes: 61.5;Late spermatids: 39.6;Sertoli cells: 46.0;Smooth muscle cells: 32.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 45.9;U-87 MG: 23.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018904 Enhanced Approved Vesicles NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA018904: AB_1844924" "unprognostic (3.70e-1)" "unprognostic (1.23e-2)" "unprognostic (5.05e-3)" "unprognostic (2.45e-4)" "unprognostic (2.04e-2)" "unprognostic (4.65e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (8.92e-3)" "unprognostic (2.29e-2)" "unprognostic (8.66e-4)" "unprognostic (1.06e-1)" "unprognostic (3.47e-9)" "unprognostic (1.14e-1)" "unprognostic (7.01e-2)" "unprognostic (5.95e-4)" "unprognostic (1.28e-3)" 16.1 6.8 16.8 7.7 18.7 0.0 15.3 15.5 20.7 75.5 9.7 174.8 5.3 89.5 6.2 15.6 70.0 7.3 48.5 19.8 14.5 4.1 1.3 8.7 0.6 16.1 15.8 21.9 3.4 4.4 34.3 4.5 14.6 58.8 3.8 1.0 10.0 25.5 118.0 7.8 31.9 23.1 15.3 2.4 48.1 5.4 15.3 0.5 5.9 21.7 0.2 87.7 42.1 15.6 6.1 0.5 3.1 4.9 1.6 4.7 1.8 13.1 8.5 8.6 6.4 4.5 1.9 0.0 4.5 9.7 4.3 7.2 2.5 3.1 3.4 0.0 1.7 0.0 6.1 0.3 2.1 0.0 0.5 13.2 4.6 7.8 1.9 45.9 0.0 3.2 3.5 0.0 6.1 1.6 0.1 18.8 6.5 0.0 2.4 2.8 7.0 1.1 8.5 0.0 3.4 15.1 0.6 0.0 0.3 14.3 0.3 0.2 0.0 20.6 21.3 2.4 21.1 0.4 0.0 0.2 23.3 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 18.7 15.5 20.7 19.8 14.5 16.1 15.8 14.6 15.3 15.3 15.6 2.4 0.0 2.2 45.7 0.4 3.2 6.0 1.3 2.8 5.3 10.3 14.6 61.5 4.3 0.1 1.8 2.1 0.6 1.4 4.1 0.0 1.5 21.8 0.9 3.6 2.2 6.7 2.7 20.5 1.2 0.9 10.0 3.6 1.3 0.0 1.0 5.7 3.1 1.1 5.0 20.9 4.1 0.0 5.6 1.9 39.6 10.5 1.6 3.6 4.7 1.4 8.4 0.0 5.0 1.0 0.2 3.2 18.8 0.9 6.5 8.5 4.3 0.1 0.9 46.0 17.1 32.4 11.6 3.7 0.2 1.4 1.4 1.2 0.4 3.5 5.3 SPINK5 "DKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTI" ENSG00000133710 "Serine peptidase inhibitor Kazal type 5" Q9NQ38 5 148025683-148137382 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 338.5;esophagus: 1015.0;skin 1: 318.2;vagina: 582.6" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 1622.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 45.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 14.7;HeLa: 22.7;Karpas-707: 19.3;SuSa: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009067, HPA011351, CAB015347" Enhanced Enhanced Vesicles "Secreted in other tissues" NA NA 43000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB015347: AB_2196138, HPA009067: AB_1080084, HPA011351: AB_1857447" "unprognostic (9.66e-3)" "unprognostic (1.42e-2)" "unprognostic (2.41e-1)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.42e-3)" "unprognostic (2.45e-2)" "unprognostic (6.85e-2)" "unprognostic (1.16e-1)" "unprognostic (2.28e-2)" "unprognostic (4.92e-3)" "unprognostic (4.56e-1)" "unprognostic (2.44e-1)" "unprognostic (7.91e-2)" "unprognostic (2.82e-1)" "unprognostic (6.87e-2)" "unprognostic (2.59e-1)" 1.1 0.3 0.0 0.5 0.1 0.0 17.5 0.0 0.2 338.5 0.0 4.8 0.3 0.6 0.3 1015.0 0.4 1.8 1.7 0.1 0.0 0.8 0.4 2.0 0.1 0.1 0.1 0.3 0.8 1.0 2.0 2.4 0.2 1.3 10.6 0.0 145.0 0.5 1.8 318.2 0.6 0.4 0.0 0.3 5.0 1.6 0.1 9.1 2.2 1.1 292.9 0.7 582.6 0.3 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.2 1.8 0.0 0.0 14.7 0.0 1.3 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.3 0.0 0.0 3.9 0.0 0.0 0.0 0.2 0.0 0.9 19.3 0.0 2.1 0.0 0.0 2.6 2.0 0.3 0.0 0.0 0.0 0.0 5.7 2.8 0.0 0.6 0.0 0.0 6.6 4.6 0.0 0.0 0.0 0.1 0.0 0.0 5.0 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.3 5.7 9.6 45.4 0.3 0.2 53.7 1.5 331.1 102.4 0.0 4.2 3.4 1.2 34.3 115.6 0.0 0.0 1.9 0.0 177.9 0.0 0.2 11.0 2.5 0.7 12.9 4.2 0.0 0.7 1.3 2.1 2.6 17.9 4.8 1.3 0.0 7.9 0.2 0.1 0.0 0.8 33.8 16.2 0.8 2.1 3.8 0.6 0.7 3.6 2.8 0.0 0.0 0.0 2.0 1.2 7.6 60.3 0.0 3.7 0.7 0.0 0.0 9.4 0.0 0.0 0.2 2.4 1.3 4.6 1622.6 64.4 1.5 1.1 1.0 97.9 2.7 SPOCK1 "SPOCK, testican-1, TIC1" ENSG00000152377 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1" Q08629 5 136975298-137598379 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 172.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 252.8;Inhibitory neurons: 349.9;Muller glia cells: 243.8;Oligodendrocyte precursor cells: 273.4;Oligodendrocytes: 913.1;Peritubular cells: 150.1" "Cancer enriched" "Detected in all" 7 "prostate cancer: 83.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 573.1;hTERT-RPE1: 1112.8;HUVEC TERT2: 594.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007450, HPA026770" Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA007450: AB_10603116, HPA026770: " "unprognostic (1.05e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (1.58e-1)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.83e-3)" "prognostic unfavorable (9.08e-4)" "unprognostic (1.00e-2)" "prognostic unfavorable (4.72e-4)" "unprognostic (9.09e-3)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.77e-5)" "prognostic unfavorable (9.40e-4)" "unprognostic (1.26e-1)" "unprognostic (2.21e-1)" "unprognostic (1.90e-2)" 29.7 41.4 67.9 4.1 116.3 0.3 19.0 129.2 99.5 25.6 9.9 24.9 1.2 44.2 34.3 6.1 18.6 18.6 54.2 100.5 50.9 24.3 0.2 2.9 0.6 80.7 84.5 4.8 5.5 13.7 9.9 9.3 89.8 65.6 3.2 48.7 7.6 25.5 17.5 9.3 4.6 30.7 78.4 8.5 9.1 21.7 102.6 7.5 9.4 7.1 0.4 11.4 21.7 172.9 4.6 0.9 299.4 0.4 573.1 116.0 0.4 100.6 90.0 207.7 115.9 0.0 0.6 0.4 0.2 206.7 53.3 4.4 1.4 70.3 65.3 17.8 0.6 0.2 16.7 0.0 4.0 0.0 0.4 203.8 28.5 128.6 23.2 1112.8 594.4 0.2 0.0 0.4 60.5 0.5 0.0 0.2 19.1 0.0 28.4 0.0 0.2 0.0 140.3 9.4 3.7 14.4 49.9 0.8 0.1 35.6 0.4 1.2 98.9 294.0 10.6 102.1 28.5 0.1 0.1 0.1 159.4 4.4 136.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 67.9 116.3 129.2 99.5 100.5 50.9 80.7 84.5 89.8 78.4 102.6 172.9 2.0 0.0 0.0 91.7 0.0 1.8 1.6 5.8 0.0 9.7 0.4 0.4 58.8 1.5 0.4 22.0 2.1 0.4 0.0 0.2 1.9 0.6 12.0 4.2 37.9 8.4 35.0 0.0 252.8 1.4 0.3 58.8 0.0 2.9 0.0 0.1 1.1 0.0 0.9 8.4 349.9 0.1 16.2 1.2 3.0 9.5 17.4 1.6 7.2 17.8 2.3 243.8 0.0 273.4 913.1 2.0 0.1 150.1 0.1 40.9 0.0 3.1 0.9 7.3 13.1 11.6 16.4 7.4 7.1 0.7 1.4 0.1 0.4 0.0 0.3 3.2 SPON2 DIL1 ENSG00000159674 "Spondin 2" Q9BUD6 4 1166932-1208962 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 187.1" "Cell type enhanced" "Detected in many" "dendritic cells: 427.0;Endometrial stromal cells: 256.6;Extravillous trophoblasts: 355.8;Fibroblasts: 257.7;NK-cells: 1096.8" "Cancer enriched" "Detected in all" 7 "prostate cancer: 243.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 255.9" "Lineage enriched" "Detected in all" 5 "T-cells: 255.9" "Group enriched" "Detected in many" 5 "HHSteC: 303.8;HSkMC: 546.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040170, HPA066095" Approved Approved Vesicles "Secreted to blood" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040170: AB_2676868, HPA066095: AB_2685615" "unprognostic (1.22e-1)" "unprognostic (3.56e-1)" "unprognostic (3.07e-2)" "prognostic favorable (2.03e-4)" "unprognostic (7.64e-2)" "unprognostic (6.28e-2)" "unprognostic (2.70e-3)" "unprognostic (2.28e-3)" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.82e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-2)" "unprognostic (2.74e-3)" "unprognostic (1.22e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (9.22e-4)" 66.2 40.4 4.0 18.8 7.7 19.5 50.6 15.6 3.9 161.4 3.5 51.5 18.5 187.1 4.4 40.6 49.7 32.2 35.5 3.5 0.8 37.1 79.1 63.0 3.9 2.9 1.7 34.4 18.7 0.9 15.1 19.2 3.5 111.8 7.2 0.7 28.8 8.4 19.1 38.3 63.5 42.7 0.2 26.9 43.8 4.7 1.8 1.8 16.3 6.6 1.0 68.4 94.0 1.5 0.4 0.6 0.0 0.0 10.2 79.0 3.0 6.2 5.0 0.8 1.0 0.0 0.1 1.8 9.7 26.9 0.9 45.0 0.0 0.2 0.0 0.3 0.1 0.2 3.0 12.7 303.8 0.2 1.5 546.6 0.0 0.6 0.0 0.0 0.0 4.1 0.3 9.2 0.0 0.3 5.3 12.2 3.5 9.7 0.7 1.0 3.3 7.9 0.0 0.0 1.7 1.1 1.1 0.0 2.9 1.7 0.4 1.5 0.1 0.2 0.9 20.5 0.0 1.3 2.7 0.6 0.1 6.5 0.0 3.7 0.9 1.0 255.9 1.1 5.5 0.7 33.1 105.8 0.4 1.0 14.4 96.8 9.8 50.4 2.2 42.9 0.1 123.2 4.0 7.7 15.6 3.9 3.5 0.8 2.9 1.7 3.5 0.2 1.8 1.5 9.8 0.0 5.6 1.3 6.6 36.8 2.0 82.5 2.2 3.7 5.1 3.8 4.0 24.3 43.0 1.8 0.0 3.4 427.0 9.7 1.9 3.8 0.2 12.7 256.6 5.7 13.8 4.0 8.4 1.3 355.8 257.7 10.7 6.6 6.3 0.2 15.4 40.4 12.8 0.0 0.6 9.7 73.2 5.8 15.4 0.5 29.8 9.5 26.6 6.5 9.2 0.9 1096.8 0.5 0.7 1.5 6.7 9.4 64.0 15.8 16.3 28.3 32.6 0.4 6.6 22.5 89.9 0.2 0.5 21.3 21.5 38.9 100.8 8.1 7.9 13.2 SPOPL BTBD33 ENSG00000144228 "Speckle type BTB/POZ protein like" Q6IQ16 2 138501770-138573547 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034687 Uncertain Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034687: AB_10670573" "unprognostic (1.39e-3)" "unprognostic (1.24e-1)" "unprognostic (2.48e-2)" "unprognostic (3.02e-2)" "unprognostic (3.37e-1)" "unprognostic (3.12e-2)" "unprognostic (4.42e-2)" "unprognostic (2.41e-1)" "unprognostic (1.40e-1)" "unprognostic (2.04e-1)" "unprognostic (2.75e-2)" "unprognostic (8.90e-2)" "prognostic favorable (3.63e-4)" "unprognostic (2.25e-2)" "unprognostic (1.15e-1)" "unprognostic (9.09e-2)" "unprognostic (1.91e-3)" 7.9 5.9 6.1 9.7 8.1 14.2 12.7 6.7 8.0 6.6 4.8 8.3 7.9 8.5 3.6 6.2 6.6 7.3 5.4 5.5 6.2 8.8 9.4 7.6 11.3 7.6 9.1 10.3 5.6 7.3 4.3 6.8 7.9 9.4 8.9 9.8 11.5 8.1 4.6 8.5 8.4 7.4 7.6 11.2 9.3 3.7 7.1 4.9 8.5 8.0 9.7 8.0 6.3 9.1 13.3 4.0 7.2 7.0 5.8 9.7 13.8 9.6 7.2 5.9 7.0 14.8 10.6 14.2 9.0 8.3 5.3 5.1 9.5 8.4 12.4 11.1 7.7 9.0 9.2 23.2 6.0 10.0 12.1 6.4 12.3 11.7 10.8 12.0 9.6 3.3 3.0 19.2 10.1 12.9 1.0 9.4 6.5 9.3 6.9 5.0 12.6 8.1 9.3 18.7 8.4 10.3 14.7 13.8 7.3 8.5 7.6 10.9 9.6 9.5 8.1 12.0 14.7 27.6 21.6 10.3 15.9 9.2 8.8 0.4 1.6 2.8 0.3 1.5 0.3 1.1 0.2 0.3 2.2 1.1 0.1 0.2 5.7 0.4 1.3 0.9 0.4 0.6 6.1 8.1 6.7 8.0 5.5 6.2 7.6 9.1 7.9 7.6 7.1 9.1 16.9 12.8 13.6 25.8 25.9 55.6 11.4 7.9 13.6 9.9 38.8 13.8 13.2 15.7 20.6 3.7 4.2 6.4 15.0 20.3 7.9 10.1 1.7 11.9 10.3 12.4 19.2 5.0 55.3 13.3 7.3 12.3 17.3 11.8 8.8 12.5 8.9 13.8 8.9 18.5 67.2 19.8 18.3 31.5 37.7 2.8 17.1 33.2 12.4 48.7 27.5 9.2 9.2 63.8 54.1 21.1 12.6 15.8 11.8 19.5 11.0 16.4 16.1 16.6 6.6 18.8 18.5 10.0 18.8 10.3 44.8 6.2 10.8 4.9 12.0 21.3 SPPL2A "IMP3, PSL2" ENSG00000138600 "Signal peptide peptidase like 2A" Q8TCT8 15 50702266-50765709 "Enzymes, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036062, HPA067304" Enhanced Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA036062: AB_10611670, HPA067304: AB_2685820" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (5.82e-3)" "unprognostic (3.71e-1)" "unprognostic (1.70e-1)" "unprognostic (2.15e-1)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (6.36e-2)" "unprognostic (2.04e-2)" "unprognostic (4.00e-2)" "unprognostic (3.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-2)" "unprognostic (6.96e-2)" "unprognostic (3.66e-1)" 41.1 34.7 8.3 57.6 10.9 54.5 32.0 11.1 8.5 36.6 48.6 93.4 79.6 27.9 21.5 26.5 26.8 39.4 37.1 6.8 12.3 57.9 107.0 43.4 40.2 15.3 12.8 13.6 63.7 158.5 13.0 54.1 12.5 29.5 82.8 12.5 44.5 32.6 109.3 25.2 67.6 41.0 11.2 37.3 41.7 18.5 12.1 39.5 35.2 81.8 41.7 51.7 20.9 14.5 57.3 96.9 37.0 49.2 142.3 84.3 58.2 89.1 149.1 80.5 114.1 113.1 64.3 35.1 65.0 176.3 120.7 83.5 45.2 54.3 89.5 72.2 27.5 67.0 61.5 58.9 117.4 42.0 104.5 73.9 98.3 66.8 106.7 59.4 80.2 37.7 51.3 134.2 107.6 131.5 20.1 16.2 15.8 90.8 22.0 24.2 57.3 77.6 109.7 130.4 29.7 33.4 54.0 102.7 63.4 74.0 73.2 81.6 98.9 128.7 51.7 83.7 106.7 54.0 100.2 38.8 58.1 69.4 90.3 48.7 52.3 48.9 27.9 48.6 17.4 18.3 22.3 25.5 37.4 19.2 12.4 20.5 37.7 23.5 56.6 33.1 30.4 50.2 8.3 10.9 11.1 8.5 6.8 12.3 15.3 12.8 12.5 11.2 12.1 14.5 66.2 48.1 35.9 20.5 51.9 43.1 79.1 76.3 37.5 14.8 36.4 21.3 77.5 52.9 44.3 68.0 20.9 136.5 72.7 215.5 23.5 87.1 18.8 107.2 56.6 59.6 38.4 30.3 32.0 167.1 88.3 74.3 52.0 57.3 45.7 20.5 46.8 124.1 85.9 8.4 31.4 86.5 36.7 68.7 55.7 7.0 44.7 83.0 32.0 23.4 134.5 27.5 64.9 25.6 26.2 131.9 127.3 36.5 49.9 92.2 143.0 46.8 41.8 17.2 26.3 88.0 51.6 31.7 15.3 39.3 38.8 204.5 60.6 30.8 76.0 94.1 SPRYD7 "C13orf1, CLLD6" ENSG00000123178 "SPRY domain containing 7" Q5W111 13 49912702-49936490 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 131.4;Spermatocytes: 167.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043934 Approved Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 54: Non-specific - Microtubule organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA043934: AB_10960545" "unprognostic (1.83e-2)" "prognostic unfavorable (8.48e-6)" "unprognostic (2.57e-1)" "unprognostic (4.95e-2)" "unprognostic (4.45e-1)" "unprognostic (1.87e-3)" "unprognostic (3.54e-2)" "unprognostic (1.12e-1)" "unprognostic (4.05e-1)" "unprognostic (3.12e-3)" "unprognostic (3.34e-3)" "unprognostic (1.17e-1)" "unprognostic (1.01e-1)" "unprognostic (6.53e-2)" "unprognostic (1.51e-1)" "unprognostic (1.65e-2)" "unprognostic (1.06e-2)" 5.3 8.6 9.4 3.8 9.9 3.2 5.6 7.9 14.6 4.9 4.8 7.6 6.3 4.3 5.3 7.7 4.7 3.1 11.6 10.3 10.4 8.4 10.7 10.2 3.2 8.6 9.0 5.4 5.5 9.5 6.0 6.2 9.8 6.4 6.6 12.3 4.7 4.9 23.9 6.0 7.2 5.2 7.9 4.0 7.0 8.9 10.0 2.6 6.7 15.4 3.6 5.7 5.4 9.1 10.1 8.5 5.4 6.0 6.5 9.2 12.3 19.5 9.1 13.5 7.7 15.5 8.1 9.8 6.1 14.4 11.1 8.5 12.1 18.1 18.7 16.3 10.9 10.5 6.5 10.9 22.1 25.4 7.2 8.0 20.0 11.8 23.0 8.4 8.4 5.5 12.0 8.6 31.6 6.2 0.9 11.9 2.1 15.3 9.6 4.7 9.1 6.0 14.1 7.6 4.5 5.6 5.7 12.8 9.8 6.8 11.9 15.7 10.8 12.2 6.8 11.3 19.8 5.3 8.8 7.5 9.5 10.2 14.0 0.7 2.0 1.7 2.0 2.3 4.1 5.3 1.9 2.6 2.5 4.3 1.5 2.3 0.4 6.8 4.6 1.7 3.1 1.8 9.4 9.9 7.9 14.6 10.3 10.4 8.6 9.0 9.8 7.9 10.0 9.1 23.7 131.4 32.8 22.2 17.0 20.3 23.3 64.1 21.1 29.4 17.2 20.1 60.1 21.5 32.1 12.9 8.4 38.8 11.2 42.4 52.8 32.1 118.5 25.9 20.0 21.5 23.4 6.5 35.5 25.8 45.0 21.4 15.3 13.3 17.7 12.5 19.2 52.1 27.9 23.5 33.3 21.4 26.4 7.6 13.9 24.3 21.1 14.1 23.2 24.4 14.6 21.6 12.3 24.6 60.1 37.2 23.6 20.3 12.4 23.9 34.5 82.1 26.6 30.7 6.6 20.1 29.8 167.1 56.9 33.8 31.0 39.8 11.9 27.7 22.2 10.4 SRR "ILV1, ISO1" ENSG00000167720 "Serine racemase" Q9GZT4 17 2303383-2325260 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Isomerase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007529, CAB015343" Approved Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "CAB015343: AB_2195009, HPA007529: AB_2667853" "unprognostic (2.96e-1)" "unprognostic (7.86e-2)" "unprognostic (6.01e-2)" "prognostic favorable (6.20e-5)" "unprognostic (3.05e-1)" "unprognostic (1.57e-2)" "unprognostic (4.32e-2)" "unprognostic (9.97e-2)" "unprognostic (9.09e-2)" "unprognostic (4.85e-2)" "prognostic favorable (8.16e-4)" "unprognostic (5.17e-2)" "prognostic favorable (2.45e-6)" "unprognostic (6.14e-2)" "unprognostic (1.99e-1)" "unprognostic (1.89e-1)" "unprognostic (5.84e-2)" 10.5 7.8 11.0 6.6 11.5 13.9 8.9 12.5 13.1 6.8 13.0 9.4 6.9 7.5 10.3 10.9 8.7 8.3 10.9 9.4 13.4 9.0 8.2 6.1 6.6 11.2 12.4 8.4 11.9 12.3 4.9 5.4 12.7 8.4 7.5 16.6 10.7 7.7 15.6 11.8 5.9 7.0 11.1 6.9 8.0 7.1 12.5 9.0 11.8 6.7 5.4 8.4 5.3 11.8 14.8 27.0 42.7 17.9 24.9 24.4 22.8 29.8 20.2 19.4 20.5 25.3 18.1 27.5 4.1 29.1 14.3 30.2 12.2 11.4 24.6 32.6 26.0 14.6 20.3 9.6 22.5 4.3 8.0 22.9 11.5 41.4 21.0 21.2 28.6 28.2 15.2 19.8 43.9 8.4 28.7 5.8 10.0 13.8 19.9 45.5 48.8 13.3 22.9 6.9 9.2 23.4 26.8 3.3 14.3 14.6 20.7 10.3 21.3 21.4 14.7 24.7 19.0 16.7 26.0 5.1 36.9 13.7 29.8 4.3 8.1 5.6 8.8 8.4 9.1 10.1 11.2 9.1 15.6 10.2 9.2 12.1 1.0 15.7 14.0 11.0 8.8 8.5 11.0 11.5 12.5 13.1 9.4 13.4 11.2 12.4 12.7 11.1 12.5 11.8 5.0 3.2 3.7 3.6 2.1 2.9 3.5 17.4 1.8 8.5 5.5 4.6 4.2 1.5 8.4 1.8 0.0 5.9 3.4 3.0 13.7 9.6 1.9 6.6 5.5 5.4 1.8 5.2 3.5 6.6 3.2 5.7 3.6 4.6 0.0 13.2 8.2 3.2 9.3 16.8 4.9 2.5 12.2 4.6 4.9 1.5 4.1 3.7 5.4 4.7 9.3 11.0 5.2 5.0 7.8 6.7 0.8 5.3 6.1 2.9 2.9 6.3 10.2 5.6 0.0 4.6 6.5 23.3 13.1 4.7 2.4 3.4 2.3 9.7 3.5 4.0 SSTR1 ENSG00000139874 "Somatostatin receptor 1" P30872 14 38207904-38213067 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0;intestine: 13.8;stomach 1: 21.7" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 18.1;Gastric mucus-secreting cells: 16.8;Hepatic stellate cells: 27.1;Oligodendrocyte precursor cells: 24.1;Paneth cells: 10.7;Proximal enterocytes: 11.8" "Cancer enhanced" "Detected in many" "prostate cancer: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 118.9;BJ hTERT+: 32.5;BJ hTERT+ SV40 Large T+: 21.4;fHDF/TERT166: 70.7;HeLa: 26.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003207, HPA031506" Approved Uncertain Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA003207: , HPA031506: AB_2673913" "unprognostic (1.40e-1)" "unprognostic (1.37e-1)" "unprognostic (3.36e-1)" "unprognostic (2.50e-3)" "unprognostic (4.34e-2)" "unprognostic (9.90e-2)" "unprognostic (3.66e-3)" "unprognostic (1.91e-1)" "unprognostic (6.16e-3)" "unprognostic (3.20e-2)" "unprognostic (1.72e-2)" "unprognostic (9.19e-2)" "prognostic favorable (4.28e-4)" "unprognostic (2.17e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" "unprognostic (3.28e-2)" 1.0 0.3 3.9 0.3 8.8 0.0 0.9 0.5 8.7 0.8 0.0 3.5 13.8 1.0 0.4 0.3 0.9 0.4 1.0 10.0 10.0 2.0 6.8 5.2 0.0 4.7 7.0 0.8 3.6 0.0 0.9 2.6 5.6 1.0 2.3 0.3 0.3 0.4 0.7 0.3 8.2 0.5 1.4 0.6 21.7 0.1 6.1 0.0 0.3 0.9 0.0 1.8 0.7 1.7 0.0 0.0 0.0 0.0 0.3 0.2 0.0 118.9 32.5 21.4 1.8 1.2 0.0 0.0 0.0 70.7 0.0 0.2 0.0 0.0 15.4 0.0 0.0 0.0 26.7 0.1 6.3 0.0 0.0 0.2 0.0 0.0 0.3 0.4 1.5 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.1 9.6 0.2 0.0 0.0 0.1 4.7 0.0 3.4 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 8.8 0.5 8.7 10.0 10.0 4.7 7.0 5.6 1.4 6.1 1.7 1.7 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 1.5 0.2 0.0 0.8 2.8 0.0 1.8 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 2.4 18.1 0.0 3.9 0.8 0.0 1.0 16.8 0.0 0.0 0.0 27.1 7.2 0.0 0.0 5.5 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 24.1 0.3 0.2 10.7 0.0 0.1 0.1 11.8 1.9 0.0 0.1 0.0 1.0 0.6 0.0 0.1 0.1 0.1 0.1 0.0 0.2 6.2 0.0 ST3GAL2 "SIAT4B, ST3GalA.2, ST3GALII" ENSG00000157350 "ST3 beta-galactoside alpha-2,3-sialyltransferase 2" Q16842 16 70375977-70439237 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 56.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 29.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017270 Approved Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA017270: AB_1857523" "unprognostic (2.76e-2)" "unprognostic (6.33e-2)" "unprognostic (3.41e-1)" "unprognostic (1.35e-1)" "unprognostic (4.99e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.14e-2)" "unprognostic (2.21e-1)" "unprognostic (1.91e-2)" "prognostic favorable (2.33e-4)" "unprognostic (9.54e-2)" "prognostic unfavorable (3.34e-6)" "unprognostic (7.42e-2)" "unprognostic (8.83e-3)" "unprognostic (4.64e-2)" "unprognostic (5.20e-2)" 8.6 8.3 4.7 6.4 5.8 7.4 7.2 8.4 6.5 9.3 1.6 9.2 3.5 12.5 1.1 2.6 8.2 2.5 10.5 7.1 2.9 8.2 10.3 9.0 6.3 3.1 2.6 7.2 3.6 2.6 6.4 3.2 2.6 7.1 1.6 1.7 3.2 2.8 15.8 4.2 7.1 4.1 1.9 13.2 4.7 6.7 3.3 3.6 6.0 3.1 3.4 8.4 5.6 2.9 1.7 8.6 7.7 11.2 3.9 5.4 2.3 6.1 6.0 6.2 3.0 5.5 4.0 4.6 9.8 6.3 5.8 1.9 3.2 2.5 3.3 9.9 5.0 18.0 4.5 8.7 4.7 6.7 29.4 4.1 1.5 6.7 1.3 8.2 8.6 7.6 25.1 4.2 3.7 1.5 7.5 19.8 10.1 2.9 4.5 13.9 2.9 5.9 5.1 1.5 3.7 9.4 15.8 0.6 7.1 8.1 2.4 7.3 9.9 9.0 10.0 4.0 4.7 8.6 3.9 9.7 10.0 5.9 12.5 4.2 1.9 5.2 2.0 1.8 1.7 2.0 2.3 2.0 1.0 2.9 3.8 3.0 10.1 2.8 1.3 14.3 2.6 1.1 4.7 5.8 8.4 6.5 7.1 2.9 3.1 2.6 2.6 1.9 3.3 2.9 15.4 9.6 5.2 13.4 12.6 3.3 4.2 2.1 2.2 15.7 2.8 3.0 6.8 10.0 1.9 9.2 14.6 4.7 56.1 4.5 0.0 5.7 16.9 1.7 6.5 15.0 13.2 24.8 21.3 4.4 2.5 11.0 2.6 2.2 17.7 19.7 18.2 13.1 13.7 18.5 15.2 4.5 2.0 15.4 35.1 33.2 11.8 11.9 1.8 17.8 24.9 5.6 23.7 16.6 7.4 1.8 1.5 8.2 13.5 3.0 6.8 5.7 1.3 11.1 6.6 8.5 8.8 9.3 8.9 1.1 2.4 1.8 11.5 4.7 5.6 2.3 ST3GAL5 "SIAT9, SIATGM3S, ST3GalV" ENSG00000115525 "ST3 beta-galactoside alpha-2,3-sialyltransferase 5" Q9UNP4 2 85837120-85905199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 47.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 112.8;Oligodendrocyte precursor cells: 94.0;Oligodendrocytes: 108.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 41.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 54.4;RT4: 47.0;SK-MEL-30: 40.8;U-266/84: 42.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034708, HPA040425, HPA068928" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA034708: AB_10601594, HPA040425: AB_2676978, HPA068928: AB_2686060" "unprognostic (7.90e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-2)" "unprognostic (2.93e-2)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" "unprognostic (1.12e-2)" "unprognostic (5.81e-3)" "unprognostic (1.38e-1)" "unprognostic (6.45e-2)" "unprognostic (5.03e-3)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.25e-7)" "unprognostic (2.22e-1)" "unprognostic (5.74e-2)" "prognostic favorable (4.99e-4)" "prognostic favorable (4.48e-4)" 17.5 47.4 17.1 4.6 26.9 2.3 8.5 16.4 20.1 5.4 7.9 5.0 1.0 9.9 0.9 2.7 10.4 8.1 4.2 16.0 24.7 2.8 9.8 14.6 9.1 24.7 22.6 10.1 3.9 0.4 12.8 17.7 23.1 6.7 2.6 31.0 7.1 0.5 12.4 6.1 6.9 3.5 20.6 20.0 5.6 10.8 23.6 5.0 27.9 3.5 4.4 20.8 5.9 41.6 0.3 27.0 2.5 54.4 22.0 11.8 8.0 5.9 18.0 5.6 5.0 0.5 19.6 0.7 0.2 10.2 2.5 1.0 3.6 6.4 7.0 0.2 3.2 0.6 1.1 1.0 17.6 0.4 7.8 6.9 0.8 2.1 0.8 10.1 13.7 7.4 0.8 30.2 18.3 1.8 1.9 3.1 0.2 9.6 0.0 3.5 17.0 11.0 2.9 47.0 3.8 3.8 0.2 0.1 40.8 5.4 0.2 1.1 4.5 0.1 2.7 0.1 0.4 30.0 42.5 0.5 4.2 5.6 27.7 0.6 0.8 0.1 0.6 3.0 0.8 1.1 0.3 0.4 0.5 0.7 0.3 0.3 0.6 0.6 2.4 0.2 0.1 0.3 17.1 26.9 16.4 20.1 16.0 24.7 24.7 22.6 23.1 20.6 23.6 41.6 8.5 86.6 112.8 37.5 29.1 5.6 27.6 20.5 1.2 56.6 3.1 2.3 1.9 40.0 33.9 3.7 58.4 0.4 48.3 0.2 3.9 12.0 12.3 9.0 27.8 8.1 6.7 0.4 46.9 16.6 1.1 21.7 6.1 8.5 34.8 35.2 29.6 21.1 35.6 72.3 60.2 0.1 12.2 45.4 18.1 12.0 8.1 24.9 32.0 45.9 20.1 56.0 12.3 94.0 108.4 6.2 0.1 1.9 19.5 6.8 0.0 3.7 10.7 45.2 0.0 21.3 5.0 8.4 16.1 0.2 3.8 0.3 28.9 6.3 0.1 8.3 ST6GALNAC5 "MGC3184, SIAT7E, ST6GalNAcV" ENSG00000117069 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5" Q9BVH7 1 76867480-77067546 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 480.3;Inhibitory neurons: 417.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.9" "Region enhanced" "Detected in many" "cerebral cortex: 5.9;hippocampal formation: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.7;fHDF/TERT166: 5.4;HaCaT: 2.7;SH-SY5Y: 4.1;U-2 OS: 4.4;U-251 MG: 2.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 51.3" "HPA065593, HPA070354" Uncertain Approved Vesicles "Intracellular and membrane" NA Yes 180000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA065593: AB_2685515, HPA070354: AB_2686260" "unprognostic (1.32e-1)" "unprognostic (5.96e-2)" "unprognostic (1.72e-1)" "unprognostic (1.49e-2)" "unprognostic (2.82e-2)" "unprognostic (2.04e-2)" "unprognostic (4.67e-2)" "unprognostic (2.72e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-1)" "unprognostic (1.61e-2)" "unprognostic (1.58e-1)" "unprognostic (2.10e-2)" "unprognostic (5.90e-3)" "unprognostic (9.66e-2)" "unprognostic (6.88e-2)" "unprognostic (1.69e-2)" 0.1 3.0 1.5 1.5 1.1 0.0 1.2 0.0 5.9 0.7 0.0 1.8 0.2 0.1 0.0 1.0 1.9 2.2 0.5 5.5 0.0 0.1 0.0 3.6 0.4 0.0 0.0 1.6 0.1 0.0 1.9 0.1 0.0 1.0 0.6 3.2 0.5 0.3 0.0 0.2 0.9 3.0 0.0 0.2 1.5 0.3 0.0 0.0 0.0 0.0 0.3 1.6 0.6 0.0 1.2 0.0 4.7 0.0 0.0 0.0 0.0 0.4 1.5 1.1 0.4 0.0 0.1 0.0 0.0 5.4 0.0 2.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.3 0.4 0.0 0.0 1.1 4.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 4.4 0.0 2.6 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 5.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.5 0.5 35.6 0.1 0.0 0.0 0.1 0.0 20.7 2.8 1.7 1.1 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.2 1.9 0.4 0.0 0.0 480.3 0.0 0.1 0.8 0.0 0.2 1.3 0.9 0.0 0.0 0.1 0.0 417.3 0.2 0.0 0.0 0.0 2.3 0.6 0.1 0.0 8.4 0.0 0.7 0.0 10.6 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 1.3 0.0 0.2 0.4 0.1 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.1 STAM STAM1 ENSG00000136738 "Signal transducing adaptor molecule" Q92783 10 17644151-17716824 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 53.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 76.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034399, HPA043882" Supported Supported Vesicles NA NA 82000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 24: Non-specific - Transcription regulation" Vesicles "CAB034399: AB_2197486, HPA043882: AB_2678713" "unprognostic (1.09e-2)" "unprognostic (8.32e-2)" "unprognostic (1.10e-1)" "unprognostic (3.95e-2)" "unprognostic (9.11e-3)" "unprognostic (1.04e-1)" "prognostic unfavorable (3.44e-6)" "unprognostic (1.39e-1)" "unprognostic (8.53e-2)" "unprognostic (8.58e-2)" "unprognostic (1.37e-2)" "unprognostic (8.39e-2)" "unprognostic (1.02e-3)" "unprognostic (1.39e-1)" "unprognostic (2.26e-1)" "unprognostic (1.87e-1)" "unprognostic (2.02e-1)" 10.8 13.3 7.7 6.9 9.7 53.1 8.9 14.0 11.8 10.7 3.4 8.0 8.2 9.0 5.8 12.2 7.8 9.1 18.0 9.2 8.7 10.2 6.9 10.9 7.5 9.8 9.5 11.4 10.4 10.3 7.4 8.5 9.8 8.7 7.7 11.2 8.5 6.1 24.5 10.0 7.3 8.5 9.6 6.8 11.4 8.1 9.1 13.1 10.8 10.1 7.5 10.9 9.0 14.7 34.8 19.8 30.8 14.2 30.1 21.9 10.3 45.1 19.8 41.0 33.1 25.9 31.7 9.1 7.2 33.9 31.7 18.2 27.6 21.1 35.0 10.9 12.7 86.3 15.3 43.1 31.8 6.5 43.7 22.7 27.0 33.6 28.3 26.6 19.8 56.3 30.1 10.5 43.8 10.4 35.7 5.6 14.7 19.7 10.2 18.0 29.0 11.9 17.5 11.2 13.0 19.2 24.6 16.7 34.6 24.1 27.5 9.4 26.6 23.9 24.5 42.7 21.1 6.6 11.5 15.6 25.6 9.6 15.6 47.5 7.5 12.5 5.9 8.2 5.6 5.4 12.8 6.2 9.6 3.1 8.8 7.1 5.9 17.3 7.5 5.5 76.5 6.4 7.7 9.7 14.0 11.8 9.2 8.7 9.8 9.5 9.8 9.6 9.1 14.7 13.2 12.8 23.4 15.7 14.1 22.9 5.3 16.2 23.9 19.7 9.4 8.9 30.0 5.7 14.0 16.5 10.4 10.2 24.3 6.4 5.9 15.1 3.5 16.3 22.3 11.0 11.4 56.8 31.7 13.4 10.5 23.5 15.8 25.9 31.6 13.0 10.4 7.8 15.5 10.1 36.9 7.8 2.0 10.4 16.3 3.5 9.6 15.6 19.6 39.4 8.4 13.7 10.3 31.7 59.4 29.9 8.0 6.0 20.8 10.1 5.7 15.6 14.0 14.5 26.3 22.3 12.6 22.1 14.6 21.8 21.0 24.6 27.6 18.4 8.1 8.5 STARD3NL "MENTHO, MGC3251" ENSG00000010270 "STARD3 N-terminal like" O95772 7 38178245-38230670 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019204 Enhanced Supported Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA019204: AB_2197800" "unprognostic (1.55e-3)" "unprognostic (2.80e-3)" "unprognostic (2.22e-1)" "unprognostic (2.58e-1)" "unprognostic (4.37e-2)" "prognostic unfavorable (2.20e-4)" "prognostic unfavorable (1.44e-5)" "unprognostic (9.64e-2)" "unprognostic (1.89e-1)" "unprognostic (5.37e-2)" "prognostic favorable (8.48e-4)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (2.41e-2)" "unprognostic (8.09e-3)" "unprognostic (2.65e-1)" "unprognostic (8.71e-2)" 26.8 21.8 35.5 23.1 37.6 37.8 22.0 39.6 41.7 31.4 29.8 21.5 18.5 32.6 27.1 12.3 27.5 22.0 27.1 35.7 44.1 34.0 17.4 32.8 21.3 42.0 46.8 24.2 16.4 17.9 25.5 49.4 48.4 40.6 23.5 26.3 14.9 21.6 17.3 6.6 20.3 33.1 40.5 27.1 17.6 32.7 41.8 22.3 32.7 17.5 15.3 29.4 14.8 42.9 40.9 42.7 92.6 60.4 62.8 62.2 32.4 65.2 67.2 63.2 82.4 34.3 63.0 31.9 64.0 59.9 192.0 42.9 51.4 49.5 95.2 29.0 45.1 64.8 22.1 47.4 55.3 71.5 72.7 58.8 24.0 67.0 53.0 72.0 116.7 86.1 75.0 53.7 98.4 25.1 40.9 115.2 65.5 33.7 33.9 49.6 85.9 14.9 89.0 37.5 36.9 86.7 22.4 58.8 64.1 127.0 40.9 93.8 80.0 43.0 61.0 67.8 93.5 57.4 62.2 12.1 87.0 125.6 142.4 33.5 46.8 56.2 52.2 43.3 23.9 30.8 21.6 39.3 42.3 28.4 18.1 35.6 53.1 71.8 47.0 30.3 24.8 47.1 35.5 37.6 39.6 41.7 35.7 44.1 42.0 46.8 48.4 40.5 41.8 42.9 45.8 19.2 47.3 15.0 33.2 20.8 57.3 43.4 20.5 8.7 26.8 15.0 18.2 14.3 25.9 31.3 12.5 48.3 67.2 15.5 31.3 31.4 125.3 37.0 42.5 45.5 21.5 28.2 21.9 34.3 91.2 34.2 19.9 33.1 23.5 36.0 51.0 12.4 65.8 5.0 24.5 20.9 32.6 63.2 77.9 115.2 18.3 56.8 26.6 17.8 24.2 34.6 114.4 27.6 26.0 34.0 21.6 25.9 34.3 55.2 19.4 50.1 22.8 13.0 13.1 23.4 38.4 48.8 37.3 12.2 16.2 42.3 47.5 24.5 19.5 46.4 STEAP2 "IPCA-1, PCANAP1, STAMP1, STMP" ENSG00000157214 "STEAP2 metalloreductase" Q8NFT2 7 90167590-90238137 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "prostate: 127.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 68.0;Inhibitory neurons: 53.0;Prostatic glandular cells: 102.9" "Cancer enriched" "Detected in many" 12 "prostate cancer: 88.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 22.5;CAPAN-2: 48.1;U-138 MG: 27.4" "Low region specificity" "Detected in all" "HPA029115, HPA055603" Uncertain Supported Vesicles NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA029115: AB_10603894, HPA055603: " "unprognostic (6.26e-3)" "unprognostic (2.48e-1)" "unprognostic (2.55e-1)" "unprognostic (1.65e-1)" "unprognostic (8.20e-4)" "unprognostic (2.34e-1)" "unprognostic (1.13e-1)" "unprognostic (3.67e-3)" "unprognostic (7.91e-2)" "unprognostic (1.70e-1)" "unprognostic (9.92e-2)" "unprognostic (1.34e-1)" "unprognostic (2.71e-2)" "unprognostic (9.73e-2)" "unprognostic (6.11e-2)" "unprognostic (9.86e-5)" "unprognostic (3.69e-2)" 20.0 3.7 7.3 11.9 10.4 0.0 13.0 8.3 18.5 9.5 6.9 15.1 6.1 7.1 2.7 6.9 14.3 10.1 15.1 11.2 6.9 6.8 4.0 20.5 0.4 3.1 5.0 17.2 8.1 10.1 19.4 0.2 3.8 127.7 7.6 3.9 11.9 6.9 1.4 4.7 9.1 10.8 5.4 2.7 11.0 1.1 6.4 3.3 7.9 1.6 1.7 15.8 9.0 5.7 3.2 22.5 0.5 6.3 11.5 11.1 0.3 2.8 5.8 0.4 0.8 4.2 48.1 0.0 0.3 7.5 8.8 1.8 4.9 3.5 0.8 0.0 4.7 0.0 0.1 1.1 1.0 0.0 0.1 8.1 0.8 11.5 2.3 9.4 6.1 0.0 0.0 0.4 6.6 0.0 0.0 0.7 9.1 0.0 2.5 0.0 0.0 0.2 10.3 6.6 0.7 2.1 3.5 0.0 0.1 1.0 16.8 0.0 5.1 27.4 6.0 3.8 2.4 0.1 0.0 0.0 11.7 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.3 10.4 8.3 18.5 11.2 6.9 3.1 5.0 3.8 5.4 6.4 5.7 0.6 0.0 1.1 18.6 0.2 4.8 21.6 20.6 9.1 7.5 16.1 10.3 18.0 18.6 19.4 12.9 2.1 0.0 0.1 15.9 0.0 1.1 0.5 2.8 3.7 2.2 15.7 2.7 68.0 7.4 0.0 27.6 10.7 2.9 0.0 30.4 3.6 5.8 0.0 1.7 53.0 9.8 10.2 0.0 6.2 0.8 15.5 0.7 0.0 2.8 0.0 23.1 0.0 27.6 2.6 11.4 24.0 15.4 0.0 102.9 13.1 10.8 16.0 1.3 0.0 14.7 5.8 3.1 6.2 4.1 5.4 0.0 0.5 9.8 13.8 25.3 STK11IP "KIAA1898, LIP1, LKB1IP, STK11IP1" ENSG00000144589 "Serine/threonine kinase 11 interacting protein" Q8N1F8 2 219597857-219616451 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 15.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036837, HPA036838, HPA053192" Approved Enhanced Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA036837: AB_10969754, HPA036838: AB_10672100, HPA053192: AB_2682075" "unprognostic (3.37e-1)" "unprognostic (1.33e-1)" "unprognostic (3.51e-1)" "unprognostic (1.97e-1)" "unprognostic (2.15e-1)" "unprognostic (3.33e-3)" "unprognostic (1.22e-3)" "unprognostic (8.36e-2)" "unprognostic (9.36e-2)" "unprognostic (1.87e-2)" "prognostic favorable (1.63e-4)" "unprognostic (9.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-3)" "unprognostic (9.44e-2)" "unprognostic (1.02e-1)" "unprognostic (2.51e-2)" 7.6 10.0 12.0 9.5 12.4 19.5 7.1 11.3 13.8 9.2 12.6 9.8 9.2 9.2 15.0 9.6 10.4 9.5 8.0 12.4 10.6 11.2 5.9 9.3 14.0 12.0 11.9 24.5 9.5 7.5 21.5 8.2 12.3 9.9 7.8 12.3 8.1 6.5 5.8 18.4 10.0 8.3 10.0 15.1 8.6 31.2 12.0 19.5 11.1 4.3 11.1 9.0 8.3 11.8 10.1 15.4 16.1 11.0 5.6 9.9 16.5 8.7 7.6 13.9 11.7 14.3 16.7 5.8 8.7 8.4 12.6 24.4 7.7 18.7 10.3 8.7 11.7 15.1 17.2 11.6 7.4 15.9 38.2 9.6 16.5 11.7 5.9 14.2 8.6 9.7 11.4 8.5 7.9 19.7 9.3 19.6 16.2 4.8 8.4 17.5 5.9 4.5 13.8 15.8 10.6 16.8 5.7 13.8 12.0 12.9 8.8 15.3 6.5 15.0 12.6 14.5 8.6 9.4 4.5 10.8 11.4 8.7 9.5 1.5 4.3 5.3 2.6 5.8 2.1 1.7 1.2 2.1 7.7 1.2 1.0 1.0 1.4 3.7 6.5 15.1 2.1 2.6 12.0 12.4 11.3 13.8 12.4 10.6 12.0 11.9 12.3 10.0 12.0 11.8 3.5 6.4 6.7 12.4 3.9 2.3 2.1 6.3 1.2 7.8 5.1 5.5 3.6 1.5 7.8 7.3 18.8 10.0 10.3 14.6 1.9 5.0 14.0 11.9 4.0 4.6 13.1 6.9 10.7 6.5 5.6 5.3 17.3 5.8 12.7 29.7 4.2 3.3 8.4 11.8 8.0 8.8 6.1 8.6 5.7 30.9 25.4 8.9 3.6 8.4 7.0 4.9 4.1 8.5 7.4 4.2 3.3 14.7 2.8 1.7 5.4 2.7 19.9 12.6 13.1 3.2 4.9 18.5 13.8 3.5 2.7 16.1 4.5 5.4 8.8 2.8 STPG3 "C9orf173, FLJ40246" ENSG00000197768 "Sperm-tail PG-rich repeat containing 3" Q8N7X2 9 137251261-137253483 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 42.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 3.3;RPMI-8226: 1.4;SK-BR-3: 1.2;T-47d: 2.0;U-266/70: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA044352 Uncertain Vesicles NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA044352: AB_10965328" "unprognostic (1.20e-1)" "unprognostic (5.32e-2)" "unprognostic (4.32e-3)" "unprognostic (4.72e-4)" "unprognostic (2.56e-1)" "unprognostic (1.22e-2)" "unprognostic (1.08e-2)" "unprognostic (2.77e-3)" "unprognostic (1.29e-1)" "unprognostic (3.93e-2)" "unprognostic (8.59e-4)" "unprognostic (2.09e-1)" "unprognostic (7.25e-2)" "unprognostic (2.65e-1)" "unprognostic (1.58e-1)" "unprognostic (1.29e-1)" "unprognostic (7.95e-2)" 0.9 0.5 0.0 0.4 0.0 0.3 0.2 0.2 0.1 0.3 0.0 0.1 3.9 0.2 0.2 0.1 0.4 0.2 0.2 0.0 0.1 1.1 1.5 0.1 0.4 0.1 0.1 0.0 1.3 0.0 0.7 0.2 0.1 0.3 0.0 1.5 1.3 0.0 0.0 0.6 3.0 0.0 0.1 0.4 0.5 42.5 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.9 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.6 0.4 0.0 0.8 0.0 0.1 0.0 0.2 0.2 0.0 0.0 1.4 0.0 0.0 0.4 0.2 0.1 1.2 0.0 0.2 2.0 0.0 0.0 0.3 0.6 0.1 0.0 1.2 0.7 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 STX16 "hsyn16, SYN16" ENSG00000124222 "Syntaxin 16" O14662 20 58651253-58679526 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041019, HPA042033" Uncertain Enhanced Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA041019: AB_10964273, HPA042033: AB_10963935" "unprognostic (7.52e-2)" "unprognostic (1.91e-1)" "unprognostic (7.96e-2)" "unprognostic (1.35e-2)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "prognostic unfavorable (4.18e-4)" "unprognostic (7.32e-2)" "unprognostic (5.11e-2)" "unprognostic (3.51e-2)" "unprognostic (2.80e-3)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.11e-16)" "unprognostic (3.35e-2)" "unprognostic (1.53e-1)" "unprognostic (1.56e-1)" "unprognostic (5.89e-2)" 39.5 44.5 42.3 34.7 43.6 54.3 42.7 38.8 45.5 60.9 36.8 56.4 26.2 50.1 44.6 40.8 58.9 24.9 38.5 39.1 39.5 47.6 45.9 44.2 46.3 44.4 42.1 58.9 50.0 21.2 68.7 26.4 44.4 52.7 26.0 38.7 43.5 30.0 33.3 53.7 49.3 27.8 39.4 65.3 44.3 36.3 42.5 33.0 49.2 19.5 32.4 55.5 49.5 50.8 37.2 21.4 27.6 26.9 49.7 52.6 38.2 45.1 30.5 45.3 28.0 41.9 53.0 42.5 61.3 32.4 56.7 53.9 25.5 53.6 37.3 20.2 26.9 26.6 63.9 51.3 49.2 38.2 57.8 58.9 80.4 30.5 46.0 84.6 46.4 49.2 31.3 36.8 36.9 86.9 29.8 45.9 11.2 30.1 35.9 27.3 25.8 29.6 34.6 27.3 18.2 27.7 47.7 82.8 83.2 46.4 33.1 50.1 49.5 74.1 36.0 28.6 50.3 75.7 37.7 23.4 54.7 29.2 31.7 18.2 5.8 5.0 4.3 5.3 4.8 2.3 3.9 3.1 3.8 3.7 5.1 4.9 12.6 5.4 3.9 3.9 4.7 4.1 42.3 43.6 38.8 45.5 39.1 39.5 44.4 42.1 44.4 39.4 42.5 50.8 40.2 22.4 46.6 0.0 27.0 26.9 19.3 22.8 29.0 65.2 44.3 41.5 24.3 41.5 31.2 29.5 85.5 24.2 33.7 23.4 5.9 16.6 6.2 32.6 51.2 36.3 46.1 26.5 0.0 13.7 20.6 28.3 38.2 26.1 19.6 54.8 37.1 30.8 22.2 42.1 0.0 25.4 20.3 42.9 35.9 8.9 22.7 37.1 21.4 0.0 44.0 29.5 33.0 0.0 0.0 19.7 22.5 29.0 16.2 20.1 30.0 12.5 45.6 52.8 13.1 32.1 30.4 47.5 20.2 35.2 42.3 17.5 42.6 27.8 26.0 21.5 SUSD4 FLJ10052 ENSG00000143502 "Sushi domain containing 4" Q5VX71 1 223220819-223364233 "Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.0;esophagus: 51.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.7;Inhibitory neurons: 89.7;Oligodendrocyte precursor cells: 101.6;Squamous epithelial cells: 68.3;Theca cells: 65.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 6.8;naive CD4 T-cell: 10.2" "Lineage enriched" "Detected in single" 40 "T-cells: 10.2" "Cell line enhanced" "Detected in some" "HaCaT: 9.7;RPTEC TERT1: 11.1;SCLC-21H: 36.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058296 Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA058296: AB_2683672" "unprognostic (2.90e-1)" "unprognostic (2.90e-3)" "unprognostic (1.27e-3)" "prognostic unfavorable (4.28e-4)" "unprognostic (2.12e-1)" "unprognostic (7.01e-2)" "unprognostic (7.53e-3)" "unprognostic (1.82e-3)" "unprognostic (7.94e-2)" "unprognostic (1.57e-1)" "unprognostic (1.27e-3)" "unprognostic (1.36e-1)" "unprognostic (6.51e-6)" "unprognostic (3.64e-2)" "unprognostic (5.11e-2)" "unprognostic (3.03e-1)" "unprognostic (7.11e-2)" 0.4 6.0 28.4 0.8 21.7 0.4 8.7 5.4 63.7 9.5 0.0 1.3 1.0 0.3 25.1 51.1 3.5 0.7 23.0 69.0 26.8 19.5 3.8 2.8 1.6 9.4 10.4 45.3 10.7 14.9 26.0 0.5 15.9 6.0 0.2 12.2 17.0 4.3 3.5 7.8 0.6 0.4 5.0 0.4 11.0 6.6 21.4 3.4 1.0 2.2 15.0 3.6 25.3 16.2 5.9 0.5 0.2 0.0 0.0 0.0 0.1 0.8 0.4 1.0 0.5 5.8 1.8 0.0 1.8 0.2 0.0 9.7 0.2 1.5 0.9 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.6 0.2 0.0 6.6 0.5 0.0 0.5 3.9 3.8 0.0 0.2 3.0 1.3 0.0 0.2 0.1 11.1 2.8 36.3 0.4 0.0 3.2 0.0 0.8 2.1 0.2 0.0 1.7 6.2 0.0 2.9 0.7 0.1 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.3 0.1 5.5 0.0 6.8 1.7 0.0 0.0 10.2 1.9 0.0 0.2 0.0 0.0 0.9 1.4 28.4 21.7 5.4 63.7 69.0 26.8 9.4 10.4 15.9 5.0 21.4 16.2 0.2 0.0 4.8 6.2 0.0 0.6 8.6 8.4 10.2 17.9 9.7 5.0 9.5 5.7 14.8 16.5 10.4 0.1 0.3 0.1 31.3 0.6 3.1 4.0 0.4 0.6 1.2 0.0 83.7 6.9 0.0 3.8 2.6 6.1 0.0 9.1 0.4 1.8 2.8 21.9 89.7 0.1 2.0 0.6 0.3 3.4 20.5 0.3 5.4 8.4 0.0 1.6 0.0 101.6 2.5 2.6 0.0 12.4 0.1 4.6 0.0 0.3 5.4 6.2 0.0 1.4 2.8 1.3 10.7 68.3 1.7 0.0 1.7 65.5 0.3 25.7 SYBU "FLJ20366, GOLSYN, KIAA1472, OCSYN, SNPHL" ENSG00000147642 Syntabulin Q9NX95 8 109573978-109691791 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 140.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 200.5;Horizontal cells: 95.9;Inhibitory neurons: 129.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "memory B-cell: 6.4;naive B-cell: 3.2" "Lineage enriched" "Detected in single" 27 "B-cells: 6.4" "Cell line enhanced" "Detected in many" "HaCaT: 24.4;PC-3: 25.7;SK-BR-3: 51.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053057 Uncertain Supported Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA053057: AB_2682028" "unprognostic (4.69e-2)" "unprognostic (1.40e-1)" "unprognostic (2.46e-1)" "unprognostic (1.31e-1)" "unprognostic (1.18e-1)" "unprognostic (4.27e-1)" "prognostic favorable (7.74e-4)" "unprognostic (1.22e-2)" "unprognostic (1.37e-1)" "unprognostic (2.16e-1)" "unprognostic (3.13e-1)" "unprognostic (5.52e-2)" "unprognostic (1.87e-3)" "unprognostic (1.68e-1)" "unprognostic (6.05e-3)" "unprognostic (6.89e-2)" "unprognostic (4.27e-2)" 32.2 38.7 39.1 3.2 42.0 0.0 22.2 44.5 52.4 10.7 4.4 15.4 10.9 5.6 11.5 5.6 20.1 10.3 6.9 42.4 58.6 4.2 52.1 8.8 4.4 24.2 34.0 9.2 140.5 1.5 30.4 2.5 36.6 8.2 19.7 26.1 21.5 11.0 3.8 9.6 12.0 6.9 22.8 1.0 28.2 1.8 50.8 5.4 12.3 7.7 7.8 5.9 8.8 30.2 8.6 5.2 3.6 0.0 0.5 0.6 2.5 3.1 0.0 0.0 0.0 7.9 5.4 0.7 0.5 2.5 1.2 24.4 0.8 5.7 0.0 0.1 11.6 0.0 15.2 8.2 6.2 0.0 0.0 1.9 7.7 0.0 7.2 0.4 3.3 0.6 0.4 1.6 3.5 0.2 0.2 0.0 0.7 7.7 25.7 0.0 0.0 0.0 9.5 2.2 16.3 1.9 6.9 51.4 1.7 2.5 6.8 0.3 5.0 0.3 2.0 0.1 1.5 1.5 0.1 0.5 10.8 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 6.4 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 39.1 42.0 44.5 52.4 42.4 58.6 24.2 34.0 36.6 22.8 50.8 30.2 39.3 9.6 7.7 16.0 4.3 5.7 2.5 8.3 17.1 46.1 10.9 9.1 2.4 30.0 18.0 11.0 8.4 4.6 0.1 3.6 3.9 5.4 1.4 29.3 3.4 11.8 34.5 0.0 200.5 9.4 0.9 7.9 5.6 20.9 0.0 0.7 10.0 39.1 0.3 95.9 129.6 22.2 2.0 0.8 4.2 0.4 2.1 0.3 1.8 21.5 0.7 2.1 0.0 22.1 5.7 3.9 9.8 0.4 0.1 11.8 16.2 0.1 15.6 7.4 0.0 16.5 4.2 1.3 1.5 3.5 3.3 0.7 0.6 0.1 13.7 4.2 SYNDIG1 "C20orf39, DSPC2, FLJ14220, IFITMD5, TMEM90B" ENSG00000101463 "Synapse differentiation inducing 1" Q9H7V2 20 24469629-24666616 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.4;heart muscle: 26.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 157.4;Microglial cells: 472.2;Oligodendrocytes: 214.3" "Cancer enhanced" "Detected in many" "glioma: 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 15.4;RH-30: 43.4;RPMI-8226: 43.6;SCLC-21H: 10.0;U-87 MG: 26.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044271, HPA059267" Enhanced Vesicles NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA044271: AB_2732515, HPA059267: AB_2683961" "unprognostic (9.33e-2)" "unprognostic (1.83e-2)" "unprognostic (2.17e-1)" "unprognostic (9.56e-2)" "unprognostic (5.03e-2)" "unprognostic (1.27e-1)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "unprognostic (1.62e-1)" "unprognostic (4.69e-2)" "unprognostic (4.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.94e-2)" "unprognostic (7.75e-3)" "unprognostic (2.21e-1)" "prognostic unfavorable (6.16e-6)" "unprognostic (1.40e-3)" 1.8 0.9 23.7 1.5 23.2 0.0 0.5 27.6 26.8 3.2 8.6 0.8 1.2 3.2 0.7 0.2 4.2 8.8 26.9 21.1 21.0 4.9 0.0 0.7 2.0 28.4 23.0 0.9 0.7 0.2 0.7 0.2 28.4 3.3 0.9 1.8 0.3 12.3 0.1 0.2 2.1 2.2 27.8 0.7 1.6 0.8 25.3 1.6 4.8 0.1 2.4 1.7 2.0 36.4 0.0 0.3 2.6 0.0 0.8 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 15.4 0.0 0.8 0.0 0.0 2.6 0.0 0.0 0.0 43.4 43.6 0.0 0.0 10.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.2 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 23.2 27.6 26.8 21.1 21.0 28.4 23.0 28.4 27.8 25.3 36.4 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 6.3 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.3 0.2 0.7 0.6 1.2 0.0 0.0 157.4 0.0 0.0 2.0 0.0 0.8 0.0 21.9 0.0 0.0 0.1 3.3 69.7 0.0 0.0 0.0 0.3 0.7 0.0 0.1 0.0 472.2 0.0 1.9 0.0 41.7 214.3 1.5 0.0 7.2 0.0 0.0 0.0 5.9 0.0 0.5 0.0 0.5 1.4 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SYT13 KIAA1427 ENSG00000019505 "Synaptotagmin 13" Q7L8C5 11 45240302-45286341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;gallbladder: 20.8;pituitary gland: 16.8" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 336.8" "Group enriched" "Detected in many" 5 "breast cancer: 13.5;colorectal cancer: 7.4;pancreatic cancer: 19.9;renal cancer: 16.9;stomach cancer: 11.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 19.1;NTERA-2: 8.8;RPTEC TERT1: 56.8;SCLC-21H: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046224, HPA056602" Uncertain Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA046224: AB_10961288, HPA056602: AB_2683185" "unprognostic (4.96e-2)" "unprognostic (1.06e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (7.79e-5)" "unprognostic (1.00e-2)" "unprognostic (4.17e-2)" "unprognostic (3.75e-2)" "unprognostic (9.83e-3)" "unprognostic (2.19e-1)" "unprognostic (7.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (5.66e-3)" "unprognostic (2.94e-2)" "unprognostic (1.76e-1)" "unprognostic (8.70e-2)" "unprognostic (5.13e-2)" 0.1 4.7 7.0 1.5 12.7 0.0 0.2 1.7 30.1 0.0 0.0 12.2 12.5 0.2 0.0 0.0 0.2 20.8 5.2 18.0 11.5 8.9 0.3 0.5 0.0 5.7 1.2 0.0 7.1 0.4 16.8 0.0 5.4 1.8 12.6 11.3 1.9 0.0 0.1 0.2 12.8 0.8 0.0 0.1 11.0 1.7 9.0 0.3 1.6 0.1 0.0 0.0 0.0 5.2 0.0 19.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 1.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 8.8 0.0 0.2 0.0 0.0 0.0 56.8 0.0 15.0 0.7 0.0 0.0 0.1 0.7 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 12.7 1.7 30.1 18.0 11.5 5.7 1.2 5.4 0.0 9.0 5.2 0.0 0.0 0.0 4.6 0.1 0.0 0.2 0.0 0.0 3.3 0.1 0.3 15.3 17.2 0.0 3.7 25.0 0.0 0.0 10.2 5.9 1.2 3.1 0.4 0.2 0.1 336.8 0.0 41.6 0.6 0.0 1.7 3.6 2.0 0.0 2.5 0.0 0.0 0.0 1.7 43.8 37.3 4.1 0.0 0.0 9.7 0.3 0.0 0.0 5.6 0.0 0.7 0.0 1.5 3.5 8.2 14.3 0.0 0.0 2.3 13.9 0.5 0.0 2.7 0.0 0.0 0.2 2.0 0.2 0.0 0.0 0.0 0.0 0.0 32.8 0.2 SYT14 "FLJ34198, sytXIV" ENSG00000143469 "Synaptotagmin 14" Q8NB59 1 209900923-210171389 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 7.0;retina: 1.9;testis: 3.2;thyroid gland: 5.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 208.7;Inhibitory neurons: 213.9;Oligodendrocyte precursor cells: 152.8;Oligodendrocytes: 197.6" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.9" "Region enriched" "Detected in some" 4 "cerebellum: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 9.7;GAMG: 6.7;hTERT-HME1: 4.7;SCLC-21H: 6.5;U-138 MG: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036963 Supported Vesicles NA NA "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA036963: AB_10670378" "unprognostic (1.38e-4)" "unprognostic (8.62e-3)" "unprognostic (1.93e-1)" "unprognostic (3.90e-4)" "unprognostic (1.97e-1)" "unprognostic (4.43e-5)" "unprognostic (1.92e-1)" "unprognostic (1.88e-2)" "unprognostic (6.85e-2)" "unprognostic (1.56e-2)" "unprognostic (3.81e-1)" "unprognostic (4.85e-3)" "unprognostic (2.30e-4)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (3.33e-3)" 0.0 0.7 0.4 0.0 0.6 0.0 0.0 7.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.2 0.0 0.6 0.0 0.4 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.2 0.2 0.0 5.0 0.0 0.0 0.0 0.0 1.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 9.7 2.2 1.2 0.0 0.0 0.0 0.0 0.1 6.7 3.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 4.7 1.1 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 3.6 0.0 0.3 0.0 0.0 0.0 0.0 1.9 6.5 2.0 0.0 0.0 3.6 0.8 0.0 0.0 1.6 6.4 3.2 0.0 0.9 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 7.0 1.0 0.4 0.3 0.4 0.2 0.4 0.1 0.2 1.6 0.0 0.0 0.0 30.3 0.0 0.0 0.1 0.0 0.0 30.1 0.2 0.0 2.2 0.0 0.0 0.0 27.1 0.0 0.0 0.0 3.9 0.3 17.0 11.6 2.9 0.2 0.0 0.0 208.7 0.6 0.0 0.2 0.0 29.3 0.0 0.9 0.0 0.0 0.0 52.2 213.9 0.0 0.0 0.0 0.0 5.0 0.6 0.2 0.0 3.7 0.0 1.6 0.0 152.8 197.6 0.3 0.0 0.0 0.0 0.7 0.0 0.4 0.0 29.4 0.0 0.9 0.2 6.0 16.8 0.0 0.0 0.0 0.1 0.7 0.0 0.2 SYT6 ENSG00000134207 "Synaptotagmin 6" Q5T7P8 1 114089291-114153880 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 13.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.1;Early spermatids: 6.1;Excitatory neurons: 5.9;Late spermatids: 14.1;Microglial cells: 27.2;Oligodendrocyte precursor cells: 7.5" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "NTERA-2: 22.0;WM-115: 15.2" "Group enriched" "Detected in all" 7 "basal ganglia: 31.2;olfactory bulb: 71.2" "Low region specificity" "Detected in many" HPA058362 Approved Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA058362: " "unprognostic (7.12e-2)" "unprognostic (2.03e-2)" "unprognostic (3.26e-3)" "unprognostic (1.04e-1)" "unprognostic (9.37e-2)" "unprognostic (2.49e-1)" "unprognostic (4.11e-2)" "unprognostic (3.60e-3)" "unprognostic (1.19e-1)" "unprognostic (4.71e-1)" "unprognostic (5.50e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-1)" "unprognostic (2.11e-3)" "unprognostic (1.48e-1)" "unprognostic (1.48e-2)" "unprognostic (1.18e-1)" 0.0 0.8 2.7 0.2 4.2 0.0 0.7 1.5 2.8 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 3.0 13.5 1.5 0.0 0.0 0.0 4.8 4.5 0.8 3.1 0.1 0.1 0.5 3.9 0.4 0.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 7.9 0.0 0.0 0.3 9.5 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 4.2 1.5 2.8 3.0 13.5 4.8 4.5 3.9 7.9 9.5 4.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.1 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 6.1 0.0 0.2 0.3 0.0 0.0 5.9 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.4 0.0 2.4 0.0 0.0 0.0 0.4 14.1 0.0 1.2 3.6 27.2 0.0 0.7 0.0 7.5 0.6 0.0 0.0 0.0 0.0 0.3 0.0 4.3 0.0 0.7 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.1 3.9 0.0 0.0 SYTL4 ENSG00000102362 "Synaptotagmin like 4" Q96C24 X 100674491-100732123 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 68.3" "Cell type enhanced" "Detected in many" "Granulosa cells: 58.1;Leydig cells: 72.7;Sertoli cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.7" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.7" "Cell line enhanced" "Detected in many" "HAP1: 29.5;HMC-1: 60.0;RT4: 40.8;TIME: 34.9" "Region enriched" "Detected in many" 5 "hypothalamus: 30.1" "Low region specificity" "Detected in all" "HPA001475, HPA001589, HPA075138" Approved Approved Vesicles NA Yes 3300000 "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA001475: AB_1080172, HPA001589: AB_1080174, HPA075138: " "unprognostic (7.82e-3)" "unprognostic (1.52e-1)" "unprognostic (3.43e-2)" "unprognostic (6.16e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (5.78e-2)" "unprognostic (1.32e-1)" "unprognostic (3.35e-2)" "unprognostic (2.81e-1)" "unprognostic (1.07e-3)" "unprognostic (5.62e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (1.30e-1)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "unprognostic (1.60e-2)" 6.9 4.1 6.9 2.2 13.2 2.3 6.0 4.5 5.1 21.7 14.1 9.8 2.1 43.1 3.1 3.9 17.8 4.0 3.2 5.2 13.1 5.6 10.5 4.7 0.7 8.4 9.3 68.3 8.3 1.2 18.8 3.6 7.4 12.7 9.7 1.3 6.1 7.2 2.3 2.0 4.9 32.7 6.1 3.3 7.4 6.8 18.0 0.6 8.8 4.9 1.7 6.1 10.2 7.9 0.3 6.0 1.6 0.0 8.5 4.8 0.1 7.7 4.9 8.0 14.3 0.7 7.6 0.0 2.0 5.4 6.9 6.8 29.5 2.3 8.4 0.0 2.6 0.1 10.8 0.4 2.1 0.0 60.0 1.7 0.5 7.3 0.4 3.1 20.5 0.0 3.0 0.0 3.8 2.0 0.1 0.0 1.2 21.2 0.0 0.0 2.4 0.0 7.0 40.8 14.5 0.6 3.1 11.5 1.7 3.0 7.1 0.6 34.9 4.2 8.8 20.9 1.9 0.1 0.0 0.1 5.2 0.0 4.8 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.1 0.0 0.0 0.0 0.8 6.9 13.2 4.5 5.1 5.2 13.1 8.4 9.3 7.4 6.1 18.0 7.9 15.6 28.9 1.7 41.8 0.5 0.1 7.7 3.1 1.2 0.2 19.0 6.6 3.8 18.6 8.0 3.7 0.0 0.4 0.7 29.1 3.9 8.9 1.6 4.3 25.8 13.5 0.0 5.0 0.5 2.3 0.4 20.0 26.5 6.2 3.8 58.1 11.4 38.6 1.3 0.0 1.0 26.9 8.2 1.6 1.9 3.8 72.7 7.2 3.6 8.4 0.5 5.4 0.0 10.6 0.2 7.2 27.1 41.8 0.5 11.9 5.8 2.6 8.1 0.6 52.6 38.1 11.8 2.6 4.4 2.6 0.9 0.0 0.9 18.0 9.6 13.8 TAC3 "LncZBTB39, LncZBTB39-1:2, NK3, NKB, NKNB, ZNEUROK1" ENSG00000166863 "Tachykinin precursor 3" Q9UHF0 12 57010000-57028883 "Disease related genes, Human disease related genes, Predicted secreted proteins" Neuropeptide "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "placenta: 431.7" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 13.9;Extravillous trophoblasts: 19.6;Inhibitory neurons: 40.0;Syncytiotrophoblasts: 18.3" "Cancer enriched" "Detected in many" 7 "urothelial cancer: 40.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "K-562: 14.4;SuSa: 13.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA045919 Supported Supported Approved Vesicles "Secreted in female reproductive system" NA NA 130000 "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA045919: AB_10960533" "unprognostic (4.53e-2)" "unprognostic (1.97e-2)" "unprognostic (8.41e-2)" "unprognostic (3.00e-2)" "unprognostic (3.61e-2)" "unprognostic (1.76e-2)" "unprognostic (5.99e-2)" "unprognostic (8.41e-2)" "unprognostic (1.34e-1)" "unprognostic (2.03e-1)" "unprognostic (5.28e-2)" "unprognostic (4.71e-14)" "unprognostic (1.58e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" 0.1 0.3 15.2 2.5 11.0 1.0 0.1 5.2 16.5 0.1 5.6 3.8 3.0 0.3 0.0 0.1 0.0 0.3 0.1 11.2 25.1 0.1 0.1 0.1 0.2 16.8 7.7 0.2 0.6 0.0 0.7 431.7 7.7 0.2 1.5 6.1 0.0 0.0 0.2 0.5 6.5 4.8 27.3 0.1 13.1 1.8 6.2 0.5 0.1 0.0 0.4 3.1 0.3 9.8 0.0 0.1 0.0 0.4 0.0 0.0 1.2 0.0 1.1 0.3 0.0 1.6 0.0 0.7 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 14.4 0.3 0.0 0.0 0.0 0.2 1.6 0.5 0.0 0.0 0.0 0.0 0.0 1.5 2.1 0.6 0.0 0.8 0.0 13.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 11.0 5.2 16.5 11.2 25.1 16.8 7.7 7.7 27.3 6.2 9.8 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.3 0.0 0.0 0.0 0.0 13.9 0.0 1.4 0.0 0.0 0.1 0.0 0.4 0.1 1.2 2.7 0.5 0.0 19.6 2.6 0.0 0.1 0.0 4.3 0.7 0.0 2.2 0.0 40.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.5 2.8 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.4 2.6 1.0 0.0 0.0 18.3 0.0 0.0 1.8 0.0 TAOK1 "FLJ14314, KIAA1361, MAP3K16, MARKK, PSK2, TAO1" ENSG00000160551 "TAO kinase 1" Q7L7X3 17 29390363-29551903 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 220.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007669 Approved Uncertain Vesicles NA NA 1600000 "Cluster 1: Neutrophils - Mixed function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA007669: AB_1080201" "unprognostic (1.46e-1)" "unprognostic (7.15e-3)" "unprognostic (2.70e-2)" "unprognostic (1.52e-1)" "unprognostic (1.81e-2)" "unprognostic (4.85e-2)" "unprognostic (1.28e-2)" "unprognostic (4.31e-2)" "unprognostic (1.15e-1)" "unprognostic (6.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (2.85e-2)" "unprognostic (5.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.66e-1)" "unprognostic (2.62e-1)" 13.7 9.1 12.0 9.8 16.0 10.5 10.3 13.8 13.1 11.8 1.2 9.5 5.2 10.8 8.5 10.3 7.9 9.6 13.2 13.3 12.8 10.2 8.6 9.8 9.9 16.4 14.5 10.3 7.8 19.4 8.0 11.7 14.9 9.0 8.5 20.9 7.8 10.0 11.4 10.4 7.3 11.7 13.2 10.4 8.1 11.7 13.9 13.2 14.5 15.2 9.5 12.1 8.7 20.4 19.3 35.0 32.1 13.4 24.1 29.8 11.3 20.0 23.9 20.3 21.1 20.7 7.9 13.8 15.8 35.9 20.7 16.3 30.4 15.7 36.4 20.7 18.2 21.0 21.3 12.2 16.6 26.5 16.7 19.4 19.6 29.0 30.6 21.3 27.3 14.0 20.7 12.0 26.7 14.2 18.5 9.5 12.0 12.9 8.6 15.1 41.2 8.8 19.1 31.5 16.1 18.7 34.6 34.4 21.1 32.6 23.6 21.6 33.6 28.0 19.7 23.7 27.5 9.3 18.6 14.0 20.3 14.8 24.3 0.6 0.5 0.5 0.6 0.6 0.5 0.5 0.6 0.7 0.5 0.6 0.7 0.7 1.7 0.5 0.6 1.4 0.4 0.3 12.0 16.0 13.8 13.1 13.3 12.8 16.4 14.5 14.9 13.2 13.9 20.4 96.9 48.1 45.8 105.8 35.9 44.5 27.4 27.0 52.9 56.6 35.5 23.2 90.2 30.0 37.7 46.0 98.0 18.7 40.5 29.3 15.6 27.3 11.8 45.0 72.0 55.4 37.7 18.7 162.3 24.3 16.0 58.0 31.6 80.1 28.5 44.3 52.1 29.5 30.1 52.2 160.5 23.7 24.4 65.6 60.4 19.8 39.7 67.3 40.9 92.8 55.8 37.1 29.9 142.2 220.8 38.9 24.0 54.2 34.2 40.4 17.6 22.1 31.0 54.7 26.3 66.1 52.1 59.1 33.2 49.5 45.9 37.6 43.1 43.0 21.1 41.6 TBC1D3 "DKFZp434P2235, PRC17, TBC1D3A" ENSG00000274611 "TBC1 domain family member 3" Q8IZP1 17 38181659-38192541 "Predicted membrane proteins" "GTPase activation" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebral cortex: 5.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.6;REH: 5.0;U-138 MG: 6.6;U-266/70: 10.3;U-266/84: 4.3;U-698: 5.4" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 29: U-266 - Adaptive immune response" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" 0.9 1.9 0.8 0.0 0.9 0.2 0.7 0.8 5.2 1.7 0.8 1.1 0.0 2.3 0.0 2.3 0.7 1.0 0.8 0.9 0.6 1.6 2.0 1.1 1.3 0.9 0.8 1.5 1.2 1.0 2.1 0.0 0.9 2.0 1.4 2.9 1.4 0.1 0.9 2.3 4.1 0.0 0.6 1.5 1.1 3.7 0.8 0.0 1.3 0.0 2.1 1.7 1.8 0.7 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.6 0.0 0.0 0.0 10.3 4.3 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.8 5.2 0.9 0.6 0.9 0.8 0.9 0.6 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3B "PRC17, TBC1D3I" ENSG00000274808 "TBC1 domain family member 3B" A6NDS4 17 36165681-36176636 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 13.8" "Cell type enriched" "Detected in some" 12 "Early spermatids: 20.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 8.6;HeLa: 8.7;T-47d: 5.9" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" "unprognostic (1.05e-1)" "unprognostic (3.63e-1)" "unprognostic (1.94e-2)" "unprognostic (1.49e-1)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.11e-1)" "unprognostic (2.83e-1)" "unprognostic (2.51e-1)" "unprognostic (1.17e-1)" "unprognostic (7.15e-2)" "unprognostic (9.96e-3)" "unprognostic (1.05e-3)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (3.56e-1)" "unprognostic (1.34e-1)" 2.4 4.0 3.6 1.3 2.9 0.9 2.5 4.2 4.0 3.7 1.9 3.6 1.4 2.2 0.2 5.8 3.2 0.6 2.1 4.8 3.0 3.6 4.2 3.1 1.0 4.6 2.2 4.0 3.6 0.4 5.0 0.5 5.8 5.0 0.5 2.4 4.3 1.0 3.7 6.0 4.3 0.5 1.0 4.9 3.1 13.8 3.9 0.8 3.2 0.3 0.6 4.2 5.0 1.3 1.1 1.8 1.1 1.3 1.1 1.3 3.6 0.9 0.5 1.0 1.5 0.4 8.6 0.2 0.7 0.5 0.4 3.8 0.5 0.8 0.3 1.5 2.8 0.6 8.7 0.5 0.6 0.2 1.0 1.1 1.7 1.1 0.2 2.4 0.7 0.9 0.5 0.8 0.3 0.1 0.8 3.4 0.4 0.3 0.4 1.1 0.3 0.1 1.1 1.1 0.7 0.9 0.8 0.5 0.6 1.4 5.9 0.8 2.0 0.4 0.3 2.9 0.4 1.2 1.0 0.4 1.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.6 2.9 4.2 4.0 4.8 3.0 4.6 2.2 5.8 1.0 3.9 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 TBC1D3C MGC44903 ENSG00000278299 "TBC1 domain family member 3C" Q6IPX1 17 38057693-38068592 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.0" "Cell type enriched" "Detected in single" 9 "Early spermatids: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "CAPAN-2: 34.4" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 43: Testis - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" 1.1 1.5 1.5 0.4 1.7 1.8 1.2 1.9 2.7 1.1 1.7 1.3 0.5 2.1 0.0 2.2 2.3 0.7 0.9 1.6 1.6 4.0 2.1 1.3 0.7 2.0 1.4 1.8 1.6 0.0 1.9 0.2 2.0 2.5 0.0 1.5 1.7 0.1 1.3 2.2 2.1 0.2 0.8 2.3 1.3 7.0 1.5 1.5 1.2 0.0 0.6 1.6 2.1 1.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.1 7.7 0.1 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 1.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.6 0.3 0.0 1.2 0.0 0.0 3.3 6.9 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.7 1.9 2.7 1.6 1.6 2.0 1.4 2.0 0.8 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3D ENSG00000274419 "TBC1 domain family member 3D" A0A087WVF3 17 38003976-38014902 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.8;Cholangiocytes: 2.8;Cone photoreceptor cells: 6.2;Pancreatic endocrine cells: 4.1;Rod photoreceptor cells: 1.9;Syncytiotrophoblasts: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.7;HaCaT: 7.0;HeLa: 9.6;RPMI-8226: 4.2;RT4: 4.9" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" 1.7 3.2 0.6 0.0 0.6 0.0 1.7 1.1 3.7 2.5 0.6 2.4 1.4 1.6 0.1 4.1 2.0 0.2 1.5 0.7 0.4 2.5 3.4 2.2 0.3 0.8 0.4 3.0 2.7 0.4 3.2 0.7 0.7 4.1 0.7 2.3 3.2 0.0 2.0 3.9 4.7 0.1 0.5 4.2 2.4 7.3 0.5 0.0 2.1 0.0 0.5 3.5 3.4 0.7 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.9 7.0 0.0 0.0 0.0 0.0 0.0 1.8 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 4.2 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 2.4 0.9 0.0 2.9 1.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 1.1 3.7 0.7 0.4 0.8 0.4 0.7 0.5 0.5 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.8 2.8 1.3 0.0 6.2 0.8 0.1 0.0 0.0 1.0 0.6 0.5 0.1 0.4 0.0 0.0 0.0 1.7 0.3 0.4 0.0 0.8 0.0 0.0 0.7 0.6 0.7 0.0 0.0 0.0 0.0 1.3 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 TBC1D3E ENSG00000278599 "TBC1 domain family member 3E" A0A087X179 17 38127951-38138862 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HHSteC: 4.1;HL-60: 1.0" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" "unprognostic (1.18e-1)" "unprognostic (3.35e-1)" "unprognostic (3.51e-1)" "unprognostic (4.22e-2)" "unprognostic (6.28e-2)" "unprognostic (1.87e-2)" "unprognostic (5.07e-3)" "unprognostic (1.32e-3)" 0.4 0.8 0.0 0.0 0.0 1.6 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.0 1.1 0.3 1.2 0.4 0.0 0.0 2.8 0.9 0.6 0.7 0.2 0.0 0.6 1.7 0.0 0.7 0.0 0.3 1.3 0.0 0.3 0.5 0.0 0.4 1.0 0.8 0.0 0.0 1.1 0.5 3.3 0.0 0.0 0.5 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 4.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3F ENSG00000275954 "TBC1 domain family member 3F" 17 36428618-36439566 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046969 Uncertain Vesicles NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA046969: " 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.2 0.3 0.2 0.0 0.0 0.3 0.1 6.8 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3G ENSG00000260287 "TBC1 domain family member 3G" Q6DHY5 17 36323884-36334759 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 26.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SiHa: 1.3" "HPA046969, HPA047745, HPA052553" Supported Approved Vesicles NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" "unprognostic (4.41e-1)" "unprognostic (1.17e-2)" "unprognostic (5.01e-2)" 0.4 0.8 0.2 0.0 0.2 0.0 0.5 0.2 0.9 0.8 0.2 0.5 0.1 0.9 0.0 1.2 1.5 0.0 0.5 0.2 0.2 2.8 1.2 0.6 0.0 0.2 0.2 0.9 0.6 0.0 0.9 0.0 0.2 1.4 0.0 0.0 0.6 0.0 0.5 1.0 0.6 0.0 0.2 1.5 0.4 26.1 0.2 0.0 0.4 0.0 0.0 1.2 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.9 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3H ENSG00000274226 "TBC1 domain family member 3H" P0C7X1 17 36377531-36388423 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "CAPAN-2: 5.9" "HPA046969, HPA047745, HPA052553" Approved Approved Vesicles NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" 0.1 0.3 1.3 0.0 1.3 0.1 0.1 1.3 1.5 0.6 1.3 0.2 0.0 0.0 0.0 0.6 0.6 0.0 0.2 1.3 1.3 1.1 0.5 0.3 0.0 1.3 1.3 0.2 0.0 0.0 0.5 0.0 1.4 0.6 0.0 0.1 0.2 0.0 0.1 0.4 0.3 0.0 1.3 0.6 0.1 4.7 1.3 0.0 0.2 0.0 0.0 0.5 0.5 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.3 1.3 1.5 1.3 1.3 1.3 1.3 1.4 1.3 1.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3I ENSG00000274933 "TBC1 domain family member 3I" A0A087WXS9 17 36253456-36264553 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 7.0" "Cell type enriched" "Detected in some" 12 "Early spermatids: 38.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "CAPAN-2: 5.3" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" 0.1 0.1 0.8 0.0 1.0 0.0 0.1 1.1 1.5 0.3 0.7 0.1 0.0 0.1 0.0 0.3 0.3 0.0 0.2 1.0 1.0 0.2 0.3 0.1 0.1 1.0 0.8 0.2 0.2 0.0 0.3 0.0 1.0 0.3 0.0 0.0 0.1 0.1 0.1 0.2 0.2 0.0 0.6 0.3 0.1 7.0 0.9 0.0 0.1 0.0 0.0 0.2 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.0 1.1 1.5 1.0 1.0 1.0 0.8 1.0 0.6 0.9 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3K ENSG00000273513 "TBC1 domain family member 3K" A0A087X1G2 17 37924415-37935365 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "T-47d: 1.4" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 6: T47d - Mammary gland" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.6 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.3 0.2 0.3 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.3 0.3 0.2 0.0 0.0 0.2 0.1 2.2 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3L ENSG00000274512 "TBC1 domain family member 3L" B9A6J9 17 37977972-37989048 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early spermatids: 5.0;Gastric mucus-secreting cells: 5.1;Glandular and luminal cells: 2.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 39.1;hTERT-RPE1: 42.8;NB-4: 38.0" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" "unprognostic (5.14e-2)" "unprognostic (8.71e-2)" "unprognostic (8.44e-2)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" "unprognostic (6.34e-2)" "unprognostic (3.19e-1)" "unprognostic (9.50e-2)" "unprognostic (1.76e-1)" "unprognostic (1.04e-1)" "unprognostic (1.80e-2)" "unprognostic (6.63e-6)" "unprognostic (2.90e-1)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (1.28e-3)" 12.9 26.7 9.5 9.7 8.8 5.7 12.3 12.6 25.1 23.0 10.8 18.2 10.9 9.8 11.4 33.8 19.1 6.1 12.6 9.3 7.6 22.9 29.8 17.8 10.1 8.8 7.5 17.4 17.6 3.5 29.0 4.7 9.2 31.0 6.6 46.9 19.8 7.2 17.5 36.3 20.3 4.4 6.4 30.3 17.0 26.1 8.5 9.8 16.4 7.6 4.8 20.6 28.0 11.8 12.8 16.7 6.6 10.0 12.3 11.1 39.1 5.7 3.8 5.1 5.9 9.3 0.2 4.3 0.2 7.3 4.5 20.5 6.1 5.4 3.4 12.6 15.5 0.0 31.9 4.0 8.6 1.7 15.4 9.4 13.0 6.6 3.7 42.8 7.0 8.0 3.4 14.6 8.4 6.8 7.6 38.0 6.3 9.6 3.7 5.0 7.7 0.0 16.1 17.2 9.0 12.5 0.0 6.6 7.7 15.3 9.6 2.7 15.7 0.0 8.6 6.7 8.0 10.2 4.8 0.0 10.2 5.3 5.8 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 1.0 0.2 0.2 0.0 0.1 0.1 9.5 8.8 12.6 25.1 9.3 7.6 8.8 7.5 9.2 6.4 8.5 11.8 0.2 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.0 0.6 0.9 0.1 0.0 0.0 1.8 0.0 0.1 0.3 0.2 0.0 0.4 5.0 1.1 0.9 0.2 0.0 0.0 1.1 0.0 0.1 0.3 5.1 2.2 0.0 0.9 0.0 0.3 0.1 0.0 1.0 0.3 0.0 0.3 0.0 0.6 0.3 0.4 0.0 1.9 0.0 0.0 0.0 0.5 0.1 0.5 1.3 0.0 0.7 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.6 0.3 0.7 0.0 0.3 0.6 0.4 0.5 0.0 TBX4 ENSG00000121075 "T-box transcription factor 4" P57082 17 61452404-61485110 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 32.3;placenta: 21.0;prostate: 9.0" "Group enriched" "Detected in some" 8 "Early spermatids: 6.2;Late spermatids: 14.6" "Cancer enhanced" "Detected in some" "lung cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 2.9;Hep G2: 1.2;OE19: 1.2;THP-1: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB032413, HPA044457" Uncertain Approved Vesicles NA NA "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB032413: AB_2200705, HPA044457: AB_2678948" "unprognostic (1.03e-2)" "unprognostic (2.05e-2)" "unprognostic (1.43e-1)" "unprognostic (1.63e-3)" "unprognostic (6.07e-2)" "unprognostic (3.80e-2)" "unprognostic (1.25e-2)" "unprognostic (4.14e-2)" "unprognostic (7.77e-3)" "unprognostic (7.41e-2)" "unprognostic (6.83e-2)" "unprognostic (1.38e-1)" "unprognostic (1.46e-8)" "unprognostic (1.92e-1)" "unprognostic (4.41e-2)" "unprognostic (6.15e-2)" "unprognostic (5.39e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.0 0.1 0.0 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 32.3 0.1 0.1 0.1 0.0 0.3 0.0 0.0 21.0 0.1 9.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 7.2 0.4 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 2.9 0.3 0.2 0.2 1.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 1.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.3 0.1 0.0 5.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TCTE1 "D6S46, DRC5, FAP155, MGC33600" ENSG00000146221 "T-complex-associated-testis-expressed 1" Q5JU00 6 44278734-44297698 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 14.4;testis: 30.0" "Group enriched" "Detected in some" 10 "Early spermatids: 161.8;Late spermatids: 359.0" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 1.0;U-266/84: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031739 Uncertain Vesicles NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA031739: AB_10601269" "unprognostic (3.27e-2)" "unprognostic (1.86e-1)" "unprognostic (2.04e-2)" "unprognostic (5.27e-3)" "unprognostic (1.55e-1)" "unprognostic (1.57e-2)" "unprognostic (7.06e-2)" "unprognostic (1.42e-2)" "unprognostic (3.46e-1)" "unprognostic (3.49e-2)" "unprognostic (1.17e-2)" "unprognostic (7.05e-2)" "unprognostic (2.23e-5)" "unprognostic (7.68e-2)" "unprognostic (3.13e-2)" "unprognostic (1.37e-3)" "unprognostic (2.68e-1)" 0.2 0.2 1.4 0.0 1.3 0.9 0.2 6.2 1.3 0.9 1.3 0.2 0.0 0.4 0.2 0.1 14.4 0.1 0.1 1.4 1.0 0.1 0.1 1.4 0.0 3.0 3.3 0.5 0.1 0.0 0.5 1.9 1.5 0.2 0.1 1.0 0.2 0.1 0.1 0.5 0.2 0.1 2.6 0.2 0.1 30.0 1.2 0.1 0.1 0.2 0.0 0.1 0.2 1.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.7 0.1 0.1 0.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.5 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.3 6.2 1.3 1.4 1.0 3.0 3.3 1.5 2.6 1.2 1.0 0.1 0.0 0.0 1.0 0.0 0.1 0.1 0.7 0.0 1.1 0.1 0.1 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 161.8 7.3 0.3 0.1 0.0 0.0 1.3 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.3 359.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.7 0.0 0.0 0.1 0.0 16.0 0.2 0.0 0.4 0.3 23.9 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 TDRD10 DKFZp434M202 ENSG00000163239 "Tudor domain containing 10" Q5VZ19 1 154502219-154548147 "Cancer-related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 55.6" "Group enriched" "Detected in some" 5 "Early spermatids: 61.8;Late spermatids: 89.0;Spermatocytes: 103.7" "Cancer enhanced" "Detected in many" "testis cancer: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 3.0;TIME: 1.4" "Not detected" "Not detected" HPA054327 Approved Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA054327: AB_2682452" "unprognostic (1.30e-1)" "unprognostic (6.33e-2)" "unprognostic (1.78e-1)" "unprognostic (5.33e-3)" "unprognostic (9.69e-3)" "unprognostic (5.80e-3)" "unprognostic (2.99e-1)" "unprognostic (5.97e-3)" "unprognostic (2.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.00e-3)" "unprognostic (1.61e-1)" "unprognostic (1.34e-3)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "prognostic favorable (8.04e-5)" "unprognostic (1.62e-1)" 11.1 4.5 3.7 0.5 3.7 0.1 6.8 3.1 3.7 5.1 3.3 2.8 0.7 4.2 2.3 2.4 6.5 1.6 7.6 3.3 3.2 3.5 4.5 8.1 0.8 3.2 3.5 10.1 0.9 0.9 2.6 1.7 3.3 3.9 1.3 0.1 1.8 1.2 1.9 2.3 3.5 1.8 3.2 8.9 1.9 55.6 3.7 0.5 11.0 1.4 0.4 3.9 3.6 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.7 3.1 3.7 3.3 3.2 3.2 3.5 3.3 3.2 3.7 3.1 10.0 3.2 6.7 4.9 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.5 1.3 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.8 0.0 0.1 8.2 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 1.3 0.7 6.1 0.4 0.4 0.0 0.5 0.0 0.0 4.0 2.1 89.0 2.5 1.0 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.4 103.7 16.5 0.1 0.3 0.0 0.0 0.1 0.0 0.0 TECPR1 "DKFZP434B0335, FLJ23419, FLJ90593, KIAA1358" ENSG00000205356 "Tectonin beta-propeller repeat containing 1" Q7Z6L1 7 98214624-98252232 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "pancreas: 84.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Rod photoreceptor cells: 66.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021061 Approved Supported Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "HPA021061: AB_1847687" "unprognostic (8.10e-3)" "unprognostic (7.89e-2)" "unprognostic (9.05e-3)" "unprognostic (5.00e-3)" "unprognostic (2.03e-1)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (1.45e-2)" "unprognostic (1.72e-1)" "unprognostic (1.88e-1)" "prognostic favorable (8.12e-4)" "unprognostic (2.48e-1)" "unprognostic (2.54e-1)" "unprognostic (1.38e-1)" "unprognostic (3.24e-1)" "unprognostic (9.46e-2)" "unprognostic (6.12e-2)" 8.4 7.0 11.7 10.4 12.3 6.1 8.0 6.5 12.5 6.4 4.7 8.5 9.2 6.8 3.0 9.8 6.9 5.7 9.9 12.7 12.9 7.7 9.2 13.3 11.8 11.8 11.2 5.7 84.9 3.1 16.7 8.6 12.7 11.6 5.0 10.2 18.9 3.8 9.1 5.9 10.8 4.7 8.5 18.6 18.3 4.6 11.5 9.5 9.6 5.0 6.7 6.8 6.6 8.2 4.4 6.1 8.4 18.3 7.2 4.3 6.2 9.1 5.0 7.1 8.7 5.8 5.4 3.6 14.4 10.6 8.8 2.8 5.7 4.2 3.0 8.8 8.0 5.3 9.4 5.3 8.5 6.5 9.9 7.5 3.4 6.9 5.3 6.6 25.2 15.1 3.6 15.0 5.4 7.2 9.4 6.8 3.3 8.6 5.9 7.8 8.5 17.7 5.4 4.8 15.0 16.9 5.4 14.9 8.5 6.1 4.8 9.2 26.0 6.7 11.5 17.4 7.6 17.6 9.8 1.9 14.0 5.6 12.5 2.5 2.9 0.9 2.2 3.2 1.3 1.8 2.9 1.7 1.8 1.6 4.8 4.2 3.5 1.0 4.9 2.4 3.0 2.3 11.7 12.3 6.5 12.5 12.7 12.9 11.8 11.2 12.7 8.5 11.5 8.2 32.2 9.6 18.4 18.3 12.3 2.3 2.2 3.7 1.8 37.1 7.0 5.8 11.2 7.2 7.0 5.5 106.3 6.0 10.9 16.0 1.9 6.4 2.1 6.9 5.5 22.9 29.3 2.1 21.1 13.4 9.8 7.2 35.7 8.1 8.2 11.0 21.0 8.5 13.7 32.0 17.8 22.9 10.2 20.5 4.0 2.2 7.2 14.2 1.8 16.9 19.5 11.4 14.4 10.1 10.1 11.9 10.3 3.4 17.4 4.1 10.8 3.6 7.7 66.7 0.0 7.5 7.4 5.5 4.5 7.1 1.8 3.4 16.0 9.0 10.0 2.9 TEX38 "ATPAF1-AS1, C1orf223, LOC374973, THEG4" ENSG00000186118 "Testis expressed 38" Q6PEX7 1 46668855-46673594 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 416 "testis: 388.6" "Group enriched" "Detected in some" 52 "Early spermatids: 2382.9;Late spermatids: 5035.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073711 Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA073711: " "unprognostic (8.46e-2)" "unprognostic (1.99e-1)" "unprognostic (3.14e-2)" "unprognostic (8.86e-2)" "unprognostic (6.81e-3)" "unprognostic (3.50e-1)" "unprognostic (1.99e-1)" "unprognostic (9.21e-2)" "unprognostic (5.39e-2)" "unprognostic (4.15e-3)" "unprognostic (4.93e-4)" "unprognostic (2.64e-1)" "unprognostic (5.28e-2)" "unprognostic (2.84e-2)" "unprognostic (7.96e-2)" "unprognostic (7.84e-2)" "unprognostic (3.48e-1)" 0.2 0.2 0.2 0.0 0.3 0.1 0.4 0.3 0.4 0.1 0.0 0.1 0.0 0.2 0.9 0.1 0.1 0.1 0.1 0.2 0.3 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.6 0.8 0.2 0.1 0.5 0.1 0.2 0.2 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.2 388.6 0.2 0.1 0.4 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.4 0.3 0.2 0.4 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.3 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.3 0.3 0.4 0.2 0.3 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2382.9 0.2 0.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5035.0 28.3 1.5 0.0 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 18.4 0.1 0.0 0.0 0.0 0.0 0.3 6.6 0.1 0.0 71.0 14.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 TEX55 "C3orf30, FLJ32859, TSCPA" ENSG00000163424 "Testis expressed 55" Q96M34 3 119146151-119160042 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 168 "testis: 53.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA062468, HPA068480" Enhanced Approved Vesicles NA NA "Cluster 74: Testis - Spermatogenesis" Vesicles "HPA062468: AB_2684772, HPA068480: " "unprognostic (4.06e-3)" "unprognostic (3.67e-2)" "unprognostic (2.66e-1)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TGFA ENSG00000163235 "Transforming growth factor alpha" P01135 2 70447284-70554193 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.3" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 59.3;Pancreatic endocrine cells: 74.5;Urothelial cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 11.3;eosinophil: 23.8;neutrophil: 23.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 23.8" "Cell line enhanced" "Detected in many" "A-431: 72.5;CAPAN-2: 82.5;HBEC3-KT: 72.3;OE19: 54.6;RPTEC TERT1: 72.6;U-87 MG: 69.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042297 Approved Approved Vesicles "Secreted to blood" No No 57900 "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA042297: AB_10793878" "unprognostic (1.23e-1)" "unprognostic (1.06e-3)" "unprognostic (3.57e-3)" "unprognostic (6.39e-2)" "unprognostic (1.41e-1)" "unprognostic (8.49e-3)" "unprognostic (1.52e-1)" "unprognostic (3.00e-3)" "unprognostic (6.69e-2)" "unprognostic (9.21e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (7.74e-2)" "unprognostic (3.70e-2)" "unprognostic (1.60e-1)" "unprognostic (9.21e-2)" "prognostic favorable (1.52e-4)" "unprognostic (9.19e-2)" 2.2 0.5 9.2 5.0 16.8 1.6 6.9 15.0 12.2 6.1 5.2 10.7 8.5 1.3 2.9 25.5 6.1 14.1 0.7 10.4 11.7 13.4 4.5 3.9 4.1 21.0 15.8 0.1 7.5 3.0 0.5 1.9 18.5 2.4 7.9 7.4 6.4 1.2 0.1 12.2 10.0 1.4 16.6 5.8 8.5 2.5 13.2 1.0 8.1 0.3 9.0 10.0 12.8 27.3 72.5 11.3 0.1 0.2 0.0 0.0 0.0 11.0 0.0 0.3 0.1 0.2 82.5 0.0 43.2 0.4 11.2 37.1 0.6 72.3 0.1 0.1 1.6 0.0 1.8 6.0 0.0 0.9 0.1 0.0 29.1 0.1 27.8 3.4 0.0 5.6 0.0 0.4 0.0 2.6 0.1 1.4 1.1 54.6 22.9 0.0 0.5 19.8 72.6 27.2 0.6 0.1 5.8 0.0 0.1 0.2 9.8 0.7 0.6 0.3 4.9 0.1 15.7 0.4 0.6 0.1 69.0 2.4 25.6 11.3 0.8 23.8 1.7 0.2 4.4 0.0 1.0 1.0 1.0 0.0 0.5 0.4 23.8 0.3 0.0 0.0 0.0 0.7 9.2 16.8 15.0 12.2 10.4 11.7 21.0 15.8 18.5 16.6 13.2 27.3 0.4 6.4 2.7 0.3 0.2 16.2 12.3 16.9 10.8 1.4 9.8 12.1 2.3 24.3 21.8 25.8 0.0 0.0 2.2 19.8 1.9 37.3 21.3 8.1 0.7 1.7 1.2 0.0 0.8 10.0 0.0 0.6 13.7 10.5 5.7 0.0 0.0 3.0 3.9 0.0 3.6 6.2 12.2 3.2 2.4 1.9 0.3 4.1 0.0 6.5 18.2 7.9 2.1 59.3 36.1 74.5 9.0 0.0 0.7 16.8 21.1 6.6 20.4 0.7 0.0 0.1 1.1 0.6 0.2 12.2 24.9 0.0 1.9 0.0 5.6 63.6 TGFB2 ENSG00000092969 "Transforming growth factor beta 2" P61812 1 218345336-218444619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Astrocytes: 119.1;Muller glia cells: 87.1" "Cancer enhanced" "Detected in all" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 59.6;hTERT-RPE1: 155.6;U-2 OS: 58.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006134 Approved Vesicles "Secreted to blood" NA Yes 4890000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA006134: " "unprognostic (7.24e-2)" "unprognostic (7.23e-2)" "unprognostic (6.32e-2)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.86e-1)" "unprognostic (3.44e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-2)" "unprognostic (2.35e-1)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (2.64e-3)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (6.04e-2)" 1.5 1.2 8.2 1.1 11.6 0.1 4.0 9.2 14.9 7.1 7.1 2.4 0.6 6.5 4.5 1.8 3.9 2.0 6.4 11.5 11.1 1.4 0.6 7.8 0.6 18.5 12.7 4.6 1.8 1.1 2.1 12.9 10.7 17.0 0.9 10.5 8.5 11.2 4.8 2.1 0.7 5.1 8.4 2.6 1.2 0.9 10.0 0.4 2.6 2.1 0.8 3.0 3.0 11.0 4.0 20.2 1.8 15.1 4.3 2.1 0.0 2.9 0.4 30.1 21.2 5.5 46.7 0.0 59.6 0.2 25.8 11.1 1.2 2.3 32.0 0.1 0.2 0.0 1.7 0.0 46.7 0.0 0.0 1.9 5.3 4.1 15.8 155.6 8.1 0.0 0.0 0.0 29.6 0.3 0.0 0.0 1.6 0.0 1.8 0.0 8.8 0.0 10.1 0.0 0.3 0.1 34.8 3.9 0.7 39.7 2.9 1.1 38.3 21.3 58.4 17.9 30.7 0.0 0.1 0.1 9.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 11.6 9.2 14.9 11.5 11.1 18.5 12.7 10.7 8.4 10.0 11.0 2.2 76.9 6.3 119.1 0.5 8.7 8.7 35.3 4.0 9.9 8.4 5.8 4.1 14.3 29.8 5.5 0.0 0.4 0.2 0.0 0.0 40.2 19.3 2.1 6.7 8.1 0.0 0.0 8.6 16.9 13.9 28.8 0.0 6.8 1.3 0.9 4.2 0.0 1.4 1.7 36.0 0.0 8.2 0.6 13.2 28.0 8.1 3.2 12.4 30.0 1.0 87.1 0.0 3.5 1.0 21.5 0.0 13.9 1.2 15.0 0.0 0.8 12.3 3.0 0.0 27.7 19.7 0.3 0.8 0.6 2.8 0.5 0.5 0.8 0.0 2.1 TGFB3 "ARVD, ARVD1" ENSG00000119699 "Transforming growth factor beta 3" P10600 14 75958097-75983011 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 28.8;Late spermatids: 48.9;Leydig cells: 27.1;Sertoli cells: 32.9;Smooth muscle cells: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "SK-BR-3: 104.6;T-47d: 75.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063582 Approved Vesicles "Secreted to blood" NA NA 44800 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA063582: AB_2685049" "unprognostic (7.84e-2)" "unprognostic (1.89e-1)" "unprognostic (4.32e-3)" "unprognostic (1.29e-1)" "unprognostic (3.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (9.79e-2)" "unprognostic (2.83e-2)" "unprognostic (1.51e-2)" "unprognostic (5.63e-2)" "unprognostic (4.10e-1)" "prognostic unfavorable (4.01e-7)" "unprognostic (6.38e-3)" "unprognostic (1.10e-1)" "unprognostic (1.22e-2)" "unprognostic (3.27e-3)" 22.2 13.0 43.4 15.8 45.8 1.0 15.6 33.5 58.4 46.6 18.4 12.8 4.1 25.5 9.6 7.7 14.5 36.6 27.9 31.2 38.4 20.5 17.6 25.7 7.2 40.9 42.3 8.0 27.7 9.9 8.3 55.4 40.0 43.6 4.8 1.8 10.8 17.9 38.6 5.0 6.6 34.3 38.9 5.3 14.1 4.5 42.2 6.5 12.3 11.0 8.8 45.8 16.2 70.1 1.1 1.5 1.1 13.4 2.1 4.3 0.4 1.0 1.5 0.7 0.7 0.8 3.4 0.1 1.0 2.8 0.4 0.9 2.9 0.7 0.3 0.8 1.5 0.1 3.5 1.5 2.7 0.6 0.9 10.2 0.4 1.0 0.4 2.3 3.2 2.7 1.5 6.3 0.8 7.0 0.8 0.8 0.4 0.8 5.3 3.3 4.2 0.7 1.2 0.6 21.9 6.3 4.3 104.6 0.8 1.5 75.2 0.5 0.8 2.0 4.5 2.1 5.8 0.8 1.3 0.4 3.6 1.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.4 45.8 33.5 58.4 31.2 38.4 40.9 42.3 40.0 38.9 42.2 70.1 8.6 0.0 2.8 5.5 0.8 4.5 1.2 2.1 1.2 0.7 15.1 6.1 3.6 0.0 3.3 1.8 4.2 0.5 1.2 1.3 0.0 0.5 16.4 2.6 9.9 10.2 0.0 0.0 1.3 1.3 0.4 28.8 0.0 2.4 0.0 0.5 7.9 0.8 0.9 0.0 3.0 2.6 6.1 0.6 4.4 48.9 27.1 0.9 10.6 1.0 0.7 2.1 3.1 5.5 4.7 0.4 0.1 12.8 0.5 20.6 1.4 0.4 4.2 3.9 32.9 13.9 24.4 0.4 1.4 2.4 3.1 1.4 1.3 1.6 0.4 0.8 TGFBR3L ENSG00000260001 "Transforming growth factor beta receptor 3 like" H3BV60 19 7914830-7919097 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 51 "pituitary gland: 106.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.3;Late spermatids: 8.6;Plasma cells: 9.2;Proximal tubular cells: 8.9;Sertoli cells: 13.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.4;REH: 4.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA074356 Enhanced Approved Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 14: REH - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA074356: AB_2686681" "unprognostic (1.57e-1)" "unprognostic (6.92e-2)" "unprognostic (3.07e-3)" "unprognostic (2.01e-2)" "unprognostic (2.63e-1)" "unprognostic (7.65e-2)" "unprognostic (9.51e-3)" "unprognostic (1.09e-1)" "unprognostic (6.96e-2)" "unprognostic (3.41e-2)" "unprognostic (2.81e-1)" "unprognostic (2.04e-1)" "unprognostic (3.50e-3)" "unprognostic (1.31e-1)" "unprognostic (2.66e-1)" "unprognostic (1.06e-1)" "unprognostic (8.62e-3)" 0.0 0.3 0.3 0.1 0.2 0.3 0.0 1.2 1.0 1.1 0.0 0.3 2.0 1.3 0.1 0.0 0.9 0.1 0.8 0.4 0.2 0.8 1.4 0.1 0.1 0.6 0.0 0.0 0.1 0.0 106.0 0.0 0.2 0.5 0.0 0.2 0.1 0.1 0.1 0.2 1.5 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.4 0.0 0.2 0.2 0.4 0.1 0.0 2.4 0.7 0.0 0.0 0.0 0.4 0.1 0.2 0.8 0.0 0.0 0.8 0.1 0.0 0.0 1.5 0.5 0.2 0.6 0.3 0.1 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.4 0.7 0.0 0.7 0.5 0.2 0.2 0.1 1.5 4.3 0.0 1.1 0.0 0.1 0.4 0.8 0.1 0.0 0.3 0.0 0.4 0.6 0.1 0.9 1.4 1.4 0.3 0.6 0.6 0.4 0.1 0.3 0.4 0.6 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.3 0.0 0.1 0.1 0.3 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.2 1.2 1.0 0.4 0.2 0.6 0.0 0.2 0.0 0.0 0.4 0.3 0.0 0.0 2.0 2.4 1.5 2.9 0.3 0.0 1.6 1.6 2.3 1.8 0.0 0.6 0.0 0.0 0.1 1.8 0.1 3.9 0.3 0.5 1.4 3.7 0.2 0.0 0.0 7.3 0.2 0.8 0.8 0.0 0.5 0.0 0.2 1.4 2.9 0.3 0.0 3.3 0.2 0.0 0.3 0.4 8.6 1.2 0.6 5.4 1.9 0.1 3.4 0.0 0.5 1.8 0.3 0.0 1.2 9.2 4.3 0.5 8.9 0.3 2.4 13.1 0.2 3.5 0.4 1.9 0.0 1.4 0.4 4.4 0.1 0.2 0.4 TGFBRAP1 "TRAP-1, TRAP1, VPS3" ENSG00000135966 "Transforming growth factor beta receptor associated protein 1" Q8WUH2 2 105264391-105329735 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037672, HPA038397" Approved Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA037672: AB_2675597, HPA038397: AB_10669782" "unprognostic (1.66e-1)" "unprognostic (1.58e-2)" "unprognostic (8.99e-2)" "unprognostic (4.49e-3)" "unprognostic (3.02e-2)" "unprognostic (6.77e-2)" "unprognostic (5.63e-3)" "unprognostic (9.15e-2)" "unprognostic (2.25e-1)" "unprognostic (2.98e-2)" "unprognostic (2.29e-1)" "unprognostic (8.30e-2)" "unprognostic (8.82e-2)" "unprognostic (3.89e-1)" "unprognostic (1.07e-1)" "unprognostic (1.01e-1)" "unprognostic (1.62e-2)" 9.6 8.1 6.5 8.0 6.3 22.7 8.1 6.1 7.2 6.6 7.7 8.1 7.2 7.8 5.4 8.3 7.0 5.9 6.6 6.8 5.4 6.7 5.0 7.4 9.4 5.8 6.4 7.6 9.9 11.4 5.1 10.4 5.9 8.3 8.2 6.2 8.3 9.3 11.8 11.1 8.0 8.9 5.6 8.5 13.5 2.5 6.5 9.1 10.9 7.7 8.3 7.8 6.6 7.2 22.5 17.5 12.5 15.5 13.3 10.5 25.4 16.0 21.8 26.6 25.3 25.9 13.6 22.7 16.9 18.2 27.1 13.5 22.4 38.1 21.9 24.3 23.8 30.7 13.8 20.7 12.1 28.6 22.4 12.7 22.5 22.2 19.6 14.1 28.7 19.5 28.0 10.9 32.6 14.9 20.4 18.3 15.9 15.4 14.5 22.9 19.8 33.0 16.4 27.3 24.7 16.5 13.2 26.1 25.8 9.0 13.1 17.5 20.8 16.7 25.4 14.1 16.4 11.3 14.8 24.7 11.9 19.6 35.3 0.4 0.8 1.1 1.8 0.7 1.5 0.6 1.2 1.0 0.6 1.0 0.7 1.1 0.3 0.9 0.5 1.0 0.9 0.7 6.5 6.3 6.1 7.2 6.8 5.4 5.8 6.4 5.9 5.6 6.5 7.2 13.7 6.4 9.5 10.4 8.1 8.0 3.5 5.6 9.1 12.4 8.8 9.3 5.9 5.7 7.1 5.5 16.7 12.4 8.9 7.5 1.9 5.4 0.1 5.2 7.0 10.6 11.3 11.3 17.0 10.8 4.8 8.5 9.7 8.3 2.5 10.8 13.9 6.7 12.9 15.2 14.8 8.2 8.2 13.8 4.4 0.5 7.5 9.9 3.6 17.8 9.5 9.0 11.3 8.5 13.5 8.3 5.2 8.2 7.6 7.7 5.8 7.3 2.7 7.2 26.3 15.8 8.1 0.4 1.2 11.5 13.1 7.4 8.8 11.1 9.2 3.1 THBS3 ENSG00000169231 "Thrombospondin 3" P49746 1 155195588-155209051 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 29 "Early spermatids: 297.1;Late spermatids: 1075.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 76.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA006293, HPA073242" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 9400000 "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA006293: AB_10602898, HPA073242: AB_2732223" "unprognostic (2.57e-1)" "unprognostic (1.63e-2)" "prognostic unfavorable (2.43e-4)" "prognostic unfavorable (1.44e-4)" "unprognostic (2.63e-1)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (4.23e-1)" "unprognostic (4.54e-2)" "unprognostic (1.20e-1)" "unprognostic (1.88e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.38e-12)" "unprognostic (2.06e-2)" "unprognostic (9.41e-2)" "unprognostic (8.50e-3)" "unprognostic (2.26e-1)" 16.7 9.3 4.5 8.9 5.1 9.1 16.3 3.0 5.3 24.9 7.9 25.0 5.4 33.6 21.0 14.1 24.4 16.7 23.2 4.9 5.4 16.4 14.5 15.6 5.7 4.8 6.7 24.9 19.1 10.8 15.9 8.8 4.5 20.0 10.7 4.7 13.3 15.5 5.8 18.8 14.1 28.6 3.3 11.0 14.5 14.9 6.4 4.4 23.6 8.0 6.2 18.8 19.4 4.2 3.3 7.8 28.3 28.9 15.1 17.5 1.7 13.3 19.6 6.1 10.9 1.0 24.0 2.2 14.7 29.4 1.8 7.9 0.8 5.0 4.5 5.3 1.9 1.9 9.8 1.1 16.3 1.6 3.9 30.3 17.2 8.9 12.2 76.2 11.0 4.9 1.7 4.6 5.5 12.0 1.3 3.0 6.5 6.9 3.9 26.2 1.2 5.3 12.7 8.2 41.7 23.8 3.4 6.5 6.8 40.7 19.1 4.1 8.5 20.1 4.6 3.8 4.7 11.1 1.4 0.5 18.2 1.7 1.7 0.0 1.6 0.6 0.6 0.8 0.4 0.5 0.9 0.7 1.3 0.2 1.0 0.3 0.7 0.3 0.2 0.2 1.7 0.8 4.5 5.1 3.0 5.3 4.9 5.4 4.8 6.7 4.5 3.3 6.4 4.2 4.0 0.0 14.3 7.2 1.4 7.9 2.6 3.1 4.6 2.5 6.6 6.1 1.7 5.7 2.8 0.0 0.0 1.7 3.5 3.3 1.9 4.9 297.1 5.3 10.3 5.6 4.8 0.8 11.2 2.5 1.8 22.6 5.6 5.0 0.0 7.5 2.9 5.4 9.9 8.4 6.3 4.3 6.1 3.8 8.6 1075.2 23.3 3.7 10.6 0.0 1.9 1.5 1.0 0.0 3.2 3.7 2.9 10.1 1.4 2.3 2.7 3.8 2.6 3.7 0.0 11.8 8.1 20.8 4.8 3.7 5.3 1.4 2.2 2.4 3.4 2.2 THBS4 ENSG00000113296 "Thrombospondin 4" P35443 5 79991311-80083287 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Tissue remodeling, Unfolded protein response" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 216.7;heart muscle: 167.9;smooth muscle: 251.4;tongue: 214.6" "Cell type enriched" "Detected in many" 4 "Sertoli cells: 493.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 46 "eosinophil: 4.5" "Lineage enriched" "Detected in single" 46 "granulocytes: 4.5" "Cell line enhanced" "Detected in some" "AF22: 3.1;THP-1: 7.0;U-2 OS: 2.8;U-266/70: 2.6" "Region enriched" "Detected in many" 8 "white matter: 85.7" "Region enriched" "Detected in many" 27 "spinal cord: 89.3" "CAB004597, HPA042426" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 510000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB004597: AB_628352, HPA042426: AB_2677992" "unprognostic (1.41e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-3)" "unprognostic (3.64e-2)" "unprognostic (9.94e-2)" "unprognostic (8.10e-2)" "unprognostic (5.64e-2)" "unprognostic (7.12e-2)" "unprognostic (1.66e-1)" "unprognostic (2.25e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (1.96e-3)" "unprognostic (2.74e-2)" "unprognostic (3.98e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (3.33e-4)" 216.7 1.2 15.4 5.2 19.6 10.6 26.8 13.8 13.0 2.1 5.0 58.1 2.2 26.8 1.6 6.0 2.5 10.4 167.9 12.2 24.5 0.7 0.3 1.3 1.1 22.3 25.3 4.1 22.8 35.7 14.3 0.2 19.9 9.0 8.7 7.5 46.5 5.7 77.2 2.9 3.3 251.4 21.7 0.3 8.6 8.7 28.0 3.6 27.0 214.6 4.0 3.5 5.8 20.0 0.1 0.0 3.1 0.2 0.2 1.3 0.3 0.1 0.1 0.9 0.3 0.1 0.4 0.1 0.1 0.2 0.8 0.1 0.1 0.4 0.8 0.1 0.4 0.3 0.0 0.2 1.7 0.0 0.0 0.9 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.0 2.4 0.0 0.0 0.0 0.9 0.0 0.2 0.0 2.5 0.7 0.0 0.0 0.2 1.3 0.0 7.0 0.0 0.0 2.8 0.2 0.2 2.6 0.1 0.4 1.1 2.2 0.6 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 19.6 13.8 13.0 12.2 24.5 22.3 25.3 19.9 21.7 28.0 20.0 57.0 0.0 1.1 37.2 0.7 0.3 0.1 0.2 2.2 1.3 0.8 1.8 9.1 0.0 0.7 3.7 56.3 0.1 0.5 0.0 0.0 0.2 40.8 0.3 0.8 9.4 9.0 0.0 9.7 0.0 0.0 84.2 0.5 0.3 0.0 5.9 0.4 0.2 0.1 1.7 12.7 0.0 0.0 0.0 0.3 7.2 0.9 2.7 1.8 6.5 0.0 2.2 0.0 60.3 24.0 0.0 0.0 43.6 0.3 1.0 0.0 0.8 0.2 1.9 493.0 78.9 116.9 14.5 2.1 0.6 1.0 0.0 2.1 1.2 0.0 0.0 TLL1 ENSG00000038295 "Tolloid like 1" O43897 4 165873237-166104457 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.0;placenta: 6.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 115.1" "Cancer enhanced" "Detected in some" "renal cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 6.0;Karpas-707: 9.6;PC-3: 3.3" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "cerebellum: 45.8" HPA060767 Approved Vesicles "Secreted to extracellular matrix" NA NA 560000 "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA060767: AB_2684357" "unprognostic (2.17e-1)" "unprognostic (6.45e-4)" "unprognostic (8.60e-2)" "unprognostic (2.65e-5)" "unprognostic (9.85e-2)" "unprognostic (2.51e-4)" "unprognostic (3.37e-2)" "unprognostic (3.61e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-4)" "unprognostic (2.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (2.13e-3)" "unprognostic (7.76e-2)" "unprognostic (6.91e-3)" "unprognostic (1.21e-5)" 3.1 0.5 0.7 1.0 5.9 0.0 2.7 20.0 8.9 1.8 0.0 1.2 0.6 1.1 0.3 0.7 1.3 2.4 0.7 9.9 5.4 1.6 0.1 1.2 1.0 3.5 6.9 0.3 2.3 0.8 0.9 6.4 4.4 0.9 0.9 1.8 0.8 0.8 0.4 1.4 1.8 1.4 0.0 0.0 0.7 0.4 3.0 0.3 1.4 0.4 0.8 1.6 1.5 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.3 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 1.3 0.0 0.9 0.0 0.0 9.6 0.0 0.0 0.0 0.1 0.9 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.9 20.0 8.9 9.9 5.4 3.5 6.9 4.4 0.0 3.0 1.1 10.2 0.0 0.6 0.0 0.0 1.8 0.3 1.3 0.6 14.1 0.2 0.1 7.1 1.5 1.8 0.0 0.0 4.4 0.0 0.0 0.0 1.5 0.1 0.0 2.0 18.9 0.0 0.0 24.9 2.0 1.4 2.4 0.0 0.1 0.0 0.0 2.5 0.0 0.3 8.4 8.0 0.1 0.0 0.0 1.0 0.0 3.1 0.1 1.8 10.3 0.0 0.1 0.0 115.1 0.5 0.1 0.0 4.5 0.0 1.1 4.0 1.1 0.8 0.7 0.0 0.2 0.3 0.1 0.2 0.1 1.7 1.9 0.8 0.0 0.6 0.2 TMBIM1 "LFG3, PP1201, RECS1" ENSG00000135926 "Transmembrane BAX inhibitor motif containing 1" Q969X1 2 218274197-218292586 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 281.2;Pancreatic endocrine cells: 294.3;Syncytiotrophoblasts: 282.1;Urothelial cells: 299.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 573.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012093, HPA070824" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA012093: AB_1858056, HPA070824: AB_2686317" "unprognostic (4.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (1.73e-3)" "unprognostic (2.34e-3)" "unprognostic (3.81e-3)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" "unprognostic (9.85e-2)" "unprognostic (3.76e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (1.69e-1)" "prognostic favorable (3.38e-4)" "unprognostic (1.22e-1)" "unprognostic (4.63e-2)" "unprognostic (2.75e-2)" "unprognostic (4.50e-1)" 231.0 120.9 118.0 84.1 135.0 96.1 165.5 124.8 123.6 146.8 112.1 143.1 152.6 119.7 92.9 333.4 97.3 135.5 123.3 109.4 131.2 123.5 170.8 175.1 55.4 194.5 144.0 93.5 240.3 125.6 50.2 172.7 150.7 97.6 140.7 15.2 155.1 89.5 219.1 185.3 174.6 127.1 139.8 65.9 212.3 25.4 134.1 41.9 158.0 185.2 106.8 172.9 215.1 144.2 183.9 66.4 3.5 47.1 404.3 170.6 188.7 175.5 217.9 103.4 117.7 169.8 449.0 40.6 123.3 263.0 194.6 305.3 59.8 399.9 100.4 151.0 23.5 264.6 41.8 205.6 183.3 2.4 252.4 161.1 370.7 210.4 265.6 108.4 111.8 6.7 169.0 75.0 182.9 6.1 2.8 46.5 2.5 382.3 60.4 5.7 28.3 33.1 142.1 573.4 2.2 3.1 58.0 214.7 122.8 36.6 56.3 39.8 168.4 182.4 50.1 84.9 64.8 35.9 45.2 17.7 179.9 41.0 105.5 352.9 136.4 298.5 107.9 172.7 91.8 77.1 98.0 89.1 93.3 61.9 64.3 70.2 167.1 66.7 221.9 25.9 116.1 190.1 118.0 135.0 124.8 123.6 109.4 131.2 194.5 144.0 150.7 139.8 134.1 144.2 47.6 73.7 25.6 20.9 37.2 81.7 96.9 85.0 51.2 2.0 28.8 26.0 26.4 78.6 66.9 69.9 0.0 139.1 51.8 266.8 13.7 175.5 0.6 45.6 42.6 50.8 22.7 66.3 2.4 281.2 146.8 61.9 110.6 78.4 50.0 16.1 28.9 50.4 104.9 0.0 2.5 67.9 52.9 45.1 50.2 2.8 54.0 69.6 46.2 14.0 22.0 22.9 48.4 5.0 35.2 294.3 177.3 59.5 30.3 151.8 204.4 37.7 34.8 1.9 13.1 35.7 45.0 1.4 12.5 86.5 101.2 282.1 41.3 9.9 69.1 299.8 TMC4 ENSG00000167608 "Transmembrane channel like 4" 19 54160108-54173250 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 45.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 160.1;Paneth cells: 119.7;Proximal enterocytes: 228.6;Respiratory ciliated cells: 155.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "OE19: 17.3;T-47d: 30.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA048635 Approved Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA048635: AB_2680470" "unprognostic (7.55e-2)" "unprognostic (1.66e-1)" "unprognostic (4.20e-2)" "unprognostic (1.49e-1)" "unprognostic (7.04e-2)" "unprognostic (1.68e-1)" "unprognostic (4.82e-2)" "unprognostic (2.19e-2)" "unprognostic (1.03e-1)" "unprognostic (2.68e-3)" "unprognostic (7.59e-2)" "unprognostic (3.09e-1)" "prognostic favorable (1.54e-8)" "unprognostic (6.70e-2)" "unprognostic (2.48e-1)" "unprognostic (8.94e-2)" "unprognostic (1.79e-2)" 2.3 0.4 0.2 0.4 0.2 0.0 12.5 0.3 0.7 8.7 0.0 38.6 33.1 3.2 0.0 14.8 16.8 8.4 5.7 0.3 0.2 25.5 2.6 11.9 0.1 0.5 0.8 1.1 45.6 4.5 21.0 0.7 0.7 21.6 12.0 0.0 42.1 4.9 1.4 5.4 37.2 0.4 0.2 0.2 31.9 0.5 0.2 0.0 31.3 0.1 0.5 18.9 9.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.8 0.1 0.1 0.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.0 17.3 0.0 0.1 0.0 0.7 0.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.7 0.3 0.2 0.5 0.8 0.7 0.2 0.2 0.1 1.5 28.9 30.0 0.7 1.5 2.4 26.9 78.6 24.5 0.3 42.5 19.8 1.7 51.5 94.4 46.0 0.0 22.7 3.7 160.1 13.7 78.2 0.0 59.7 6.6 2.2 41.6 0.0 0.6 64.1 6.1 1.8 102.4 56.2 5.7 0.5 1.1 0.6 3.9 0.0 0.6 92.7 57.0 1.3 3.0 0.1 1.2 3.2 1.8 0.0 2.1 0.1 4.1 1.0 0.7 50.7 119.7 0.7 2.4 22.0 228.6 29.0 155.7 0.5 26.3 0.9 13.6 0.4 1.9 22.0 1.7 23.4 2.8 2.1 77.1 43.1 TMC7 FLJ21240 ENSG00000170537 "Transmembrane channel like 7" Q7Z402 16 18983934-19063942 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.9;testis: 9.6" "Group enriched" "Detected in many" 6 "Early spermatids: 172.0;Late spermatids: 44.6;Oligodendrocytes: 96.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029465 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA029465: AB_10600914" "unprognostic (1.80e-4)" "unprognostic (6.13e-2)" "unprognostic (1.82e-1)" "unprognostic (2.07e-3)" "unprognostic (1.25e-1)" "unprognostic (1.19e-3)" "unprognostic (7.60e-5)" "prognostic unfavorable (3.20e-4)" "unprognostic (7.60e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.64e-4)" "unprognostic (3.39e-1)" "unprognostic (1.00e-1)" "unprognostic (1.75e-1)" "unprognostic (1.94e-1)" "unprognostic (5.66e-2)" "prognostic favorable (9.20e-4)" 2.1 0.2 6.0 1.0 15.8 0.3 1.7 12.4 10.6 0.5 0.4 3.8 2.5 0.7 0.6 0.4 0.4 1.4 1.4 7.0 9.0 0.6 0.3 2.9 0.3 13.8 13.2 0.2 0.4 0.4 0.3 4.3 12.6 1.5 4.5 1.1 0.4 0.9 0.9 1.1 2.7 1.1 7.5 0.6 3.1 9.6 15.0 0.2 0.8 0.9 0.2 8.1 0.8 23.9 1.9 3.5 1.0 1.9 0.2 1.6 4.8 0.6 1.0 0.7 1.5 1.2 8.5 0.2 7.9 0.7 1.8 6.8 2.9 2.8 0.9 0.1 2.0 0.1 3.6 5.5 0.2 0.2 0.1 0.3 4.1 6.5 7.2 2.2 2.6 3.8 2.2 0.2 2.8 3.9 0.3 0.3 3.1 11.1 5.1 0.2 3.1 0.2 1.3 8.7 0.6 1.9 2.1 5.4 0.6 4.9 1.7 0.6 2.3 1.1 1.8 1.3 3.3 0.4 0.9 0.2 5.4 0.3 1.0 0.7 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.2 0.1 0.1 0.5 0.3 0.1 0.2 0.1 0.0 6.0 15.8 12.4 10.6 7.0 9.0 13.8 13.2 12.6 7.5 15.0 23.9 12.6 3.2 6.2 3.9 0.1 0.4 4.4 3.2 0.0 0.6 1.3 0.4 0.7 1.5 2.0 0.0 0.0 0.2 0.0 13.4 0.0 4.1 172.0 1.4 0.4 4.9 1.2 2.7 7.5 11.0 2.3 0.6 9.2 2.4 0.0 1.2 4.6 0.2 0.2 0.0 12.1 6.0 4.1 0.0 1.2 44.6 1.2 0.6 0.0 6.5 0.2 0.3 2.1 6.6 96.5 14.0 8.0 0.4 0.1 2.3 3.6 0.3 0.9 2.7 0.0 1.6 2.2 6.9 12.1 1.9 1.0 0.3 0.4 0.1 7.6 17.3 TMED2 "P24A, p24b1, p24beta1, RNP24" ENSG00000086598 "Transmembrane p24 trafficking protein 2" Q15363 12 123584533-123598582 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014060 Approved Supported Vesicles NA NA 82000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA014060: AB_1856389" "unprognostic (6.36e-2)" "unprognostic (3.38e-3)" "unprognostic (5.41e-3)" "unprognostic (1.75e-2)" "unprognostic (2.98e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.57e-3)" "unprognostic (2.20e-2)" "unprognostic (4.31e-2)" "unprognostic (9.76e-3)" "unprognostic (1.03e-2)" "unprognostic (3.94e-2)" "prognostic unfavorable (2.35e-7)" "unprognostic (2.97e-1)" "unprognostic (1.63e-1)" "unprognostic (1.51e-1)" "unprognostic (9.87e-2)" 106.0 97.1 40.7 92.6 43.5 122.1 136.1 44.2 50.8 155.6 59.5 132.5 123.7 102.5 203.3 111.9 102.3 96.1 116.5 40.5 45.3 102.8 271.1 85.4 72.7 46.6 46.6 101.5 229.1 99.3 65.0 125.4 46.9 140.5 140.7 56.9 227.6 102.2 131.0 74.8 110.5 102.1 46.0 63.2 133.8 58.5 44.2 69.1 197.6 112.1 95.2 118.6 71.4 53.8 237.7 204.9 133.4 232.2 295.7 260.2 317.5 401.2 318.5 246.8 194.2 209.9 198.9 199.3 210.7 398.7 169.4 228.1 181.8 214.5 257.3 155.2 169.3 217.3 114.0 267.6 559.5 296.9 178.1 220.5 349.2 212.6 286.0 352.7 234.7 133.5 223.1 132.9 255.6 175.1 159.8 242.7 192.9 201.0 206.6 164.8 216.8 235.7 303.9 349.1 166.5 143.1 267.3 263.6 273.7 160.0 450.2 237.2 226.2 210.1 132.4 204.9 227.5 292.3 290.7 167.6 248.3 192.9 254.2 249.7 143.2 145.9 157.0 147.5 198.8 111.8 137.0 148.4 158.6 102.5 110.3 129.4 111.1 148.5 141.3 242.5 140.1 142.2 40.7 43.5 44.2 50.8 40.5 45.3 46.6 46.6 46.9 46.0 44.2 53.8 97.1 48.1 71.5 9.1 148.8 417.4 290.3 348.5 207.1 50.1 258.8 98.0 167.2 213.1 233.2 154.5 20.9 281.5 166.9 169.6 117.4 325.1 12.2 89.2 136.5 142.0 170.7 76.3 20.0 249.6 678.6 242.7 156.5 136.8 92.6 88.4 143.5 538.8 215.8 48.8 20.3 352.4 321.4 141.7 414.3 13.9 181.4 128.5 378.8 17.8 129.8 124.1 195.7 19.6 27.5 224.9 158.5 153.4 521.0 486.3 178.1 163.0 142.1 54.7 164.3 112.6 193.5 165.9 150.6 289.8 498.8 451.9 154.3 125.0 263.9 389.2 TMEM102 "CBAP, FLJ36878" ENSG00000181284 "Transmembrane protein 102" Q8N9M5 17 7435435-7437679 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 69.0;Pancreatic endocrine cells: 32.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 3.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 10.6;HMC-1: 11.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024433 Uncertain Approved Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA024433: AB_1858071" "unprognostic (2.42e-2)" "unprognostic (2.52e-2)" "unprognostic (1.54e-2)" "unprognostic (1.64e-1)" "unprognostic (1.10e-2)" "unprognostic (9.24e-2)" "unprognostic (2.46e-1)" "unprognostic (1.61e-1)" "unprognostic (2.91e-2)" "unprognostic (2.69e-2)" "unprognostic (2.69e-1)" "unprognostic (4.95e-2)" "prognostic favorable (9.90e-4)" "unprognostic (1.10e-3)" "unprognostic (8.40e-2)" "unprognostic (1.67e-1)" "unprognostic (1.42e-3)" 2.6 8.1 0.4 1.5 0.6 1.5 3.4 0.7 0.3 3.2 0.2 5.9 2.8 1.8 1.0 10.2 1.7 1.0 2.0 0.3 0.3 5.2 4.4 3.1 2.5 0.7 0.6 0.5 5.4 1.6 1.0 0.8 0.6 2.3 1.0 0.2 6.2 0.7 3.6 8.8 6.0 0.3 0.5 6.4 4.4 6.7 0.6 1.5 3.8 0.1 1.8 2.6 4.6 0.6 5.3 3.7 0.4 0.0 1.3 0.6 2.9 1.1 1.4 0.7 1.5 2.0 5.5 5.3 4.8 0.5 0.7 10.6 0.9 5.8 0.1 4.8 6.5 4.9 2.2 1.9 0.6 2.9 11.9 0.4 5.4 0.4 1.0 1.8 2.4 4.5 1.9 0.3 0.0 3.2 3.3 5.2 0.2 5.1 3.0 5.4 0.4 1.9 5.0 3.4 0.2 3.4 0.6 4.7 1.4 0.9 2.5 1.2 3.2 0.2 0.3 0.6 0.1 1.0 1.4 0.7 1.6 2.5 2.4 0.0 0.4 3.8 0.7 0.9 0.4 0.8 0.8 0.9 0.5 0.8 0.6 0.6 0.0 1.0 1.0 0.5 0.7 0.4 0.4 0.6 0.7 0.3 0.3 0.3 0.7 0.6 0.6 0.5 0.6 0.6 2.4 0.0 0.0 0.0 8.8 3.7 5.6 5.2 8.6 0.0 4.0 3.4 1.1 7.2 4.2 1.8 0.0 9.1 6.5 18.2 7.9 21.6 16.8 7.1 1.1 3.0 1.2 2.5 0.1 21.9 7.9 0.4 9.7 11.0 0.0 4.5 2.2 3.6 7.1 1.7 0.1 8.2 6.1 7.2 10.6 69.0 0.9 4.5 1.8 0.0 11.6 1.6 8.2 0.0 0.5 32.5 15.3 0.7 5.9 2.9 15.2 9.0 2.4 0.6 0.0 0.4 1.4 1.1 2.7 5.7 7.1 5.1 8.1 0.6 7.6 13.1 TMEM135 FLJ22104 ENSG00000166575 "Transmembrane protein 135" Q86UB9 11 87037844-87328824 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 121.8;Excitatory neurons: 99.6;Inhibitory neurons: 93.7;Oligodendrocyte precursor cells: 123.1;Oligodendrocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 88.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056685, HPA069473" Uncertain Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA056685: AB_2683208, HPA069473: AB_2686139" "unprognostic (1.55e-2)" "unprognostic (1.11e-1)" "unprognostic (2.70e-2)" "unprognostic (6.51e-2)" "unprognostic (3.10e-2)" "unprognostic (4.42e-1)" "unprognostic (1.45e-2)" "unprognostic (2.63e-1)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (1.65e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (7.34e-2)" "unprognostic (1.35e-2)" "unprognostic (1.80e-1)" 26.1 14.9 4.2 5.6 6.0 3.7 14.2 2.8 5.2 5.6 5.8 10.5 15.6 6.4 4.7 4.4 6.0 8.3 6.7 4.9 5.2 12.0 24.7 6.5 5.9 5.0 5.8 7.3 6.2 9.4 5.4 10.2 5.6 10.7 8.5 7.0 10.0 6.4 8.4 3.9 14.5 6.9 2.5 5.8 7.4 10.2 4.3 6.6 10.1 7.5 4.8 5.5 4.4 6.7 8.8 15.7 9.8 13.7 31.3 28.6 9.2 6.5 16.7 7.6 17.0 27.1 39.9 24.2 17.1 8.9 19.9 8.3 13.3 14.9 8.5 22.7 7.5 18.5 14.0 88.5 17.6 10.8 9.2 34.8 9.2 11.0 7.6 10.2 19.5 26.4 19.3 35.9 9.0 5.9 28.3 10.8 11.5 47.2 11.7 12.5 7.5 19.2 17.5 28.1 4.8 11.0 9.6 30.0 13.6 18.8 42.0 9.6 10.3 7.9 10.3 30.6 4.6 13.4 28.2 28.2 6.0 11.5 15.7 0.9 4.8 1.4 7.5 5.1 6.7 4.7 4.7 8.1 5.6 3.4 5.3 5.1 1.5 7.2 2.2 5.7 5.4 4.1 4.2 6.0 2.8 5.2 4.9 5.2 5.0 5.8 5.6 2.5 4.3 6.7 14.4 9.6 7.5 121.8 7.1 4.2 4.0 4.6 8.6 5.6 12.7 7.1 6.3 5.7 6.8 1.8 4.2 2.6 7.7 10.5 5.9 2.8 2.8 5.8 11.0 8.1 3.6 3.8 99.6 3.2 8.6 11.0 8.6 4.2 9.5 11.5 7.9 16.2 4.9 1.7 93.7 6.8 10.2 7.8 6.0 7.7 7.2 5.4 5.4 48.7 4.1 5.0 9.2 123.1 202.4 3.1 10.9 7.2 10.3 6.1 21.8 10.6 8.7 4.2 32.9 5.7 8.4 2.2 3.8 4.8 4.8 1.5 8.3 24.6 8.7 3.8 TMEM145 FLJ90805 ENSG00000167619 "Transmembrane protein 145" Q8NBT3 19 42313309-42325064 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 67.8;pituitary gland: 18.3;retina: 28.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 64.5;Cone photoreceptor cells: 29.2;Excitatory neurons: 26.5;Horizontal cells: 69.0;Inhibitory neurons: 54.3;Rod photoreceptor cells: 33.0" "Cancer enriched" "Detected in many" 5 "glioma: 8.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 6.8;neutrophil: 14.2" "Lineage enriched" "Detected in many" 11 "granulocytes: 14.2" "Cell line enhanced" "Detected in many" "HMC-1: 13.7;PC-3: 11.6;SCLC-21H: 26.2;SH-SY5Y: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060462 Enhanced Approved Approved Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA060462: AB_2684285" "unprognostic (9.56e-3)" "unprognostic (8.61e-2)" "unprognostic (6.65e-2)" "unprognostic (1.19e-1)" "unprognostic (2.96e-1)" "unprognostic (3.02e-1)" "unprognostic (1.47e-1)" "unprognostic (6.62e-2)" "unprognostic (2.14e-1)" "unprognostic (4.27e-3)" "unprognostic (1.53e-2)" "unprognostic (9.85e-2)" "unprognostic (4.20e-4)" "unprognostic (7.35e-2)" "unprognostic (7.64e-2)" "unprognostic (2.30e-1)" "unprognostic (6.31e-2)" 1.0 4.3 17.7 0.7 21.0 2.0 0.7 67.8 37.3 0.2 0.1 0.8 1.2 0.6 1.0 0.5 0.6 0.8 0.9 16.5 15.6 0.5 0.7 0.3 1.1 17.8 20.0 0.6 2.5 1.8 18.3 0.2 18.2 0.5 0.6 28.8 0.5 0.5 1.8 2.3 0.6 0.6 10.7 0.9 1.2 4.2 19.2 0.4 0.7 0.8 0.5 0.6 0.2 21.0 0.7 3.2 2.4 7.3 0.2 0.2 1.0 0.3 0.1 1.1 3.0 0.6 0.9 1.9 0.3 1.2 0.7 0.3 1.7 0.6 1.5 8.5 2.0 3.5 3.5 3.1 0.2 2.0 13.7 0.7 0.6 0.4 0.8 0.2 1.4 1.0 1.9 6.6 0.1 0.7 0.5 2.5 1.7 2.4 11.6 0.3 0.8 6.2 0.1 1.3 26.2 12.7 1.2 0.9 1.7 0.2 2.3 2.1 0.5 2.0 2.3 1.6 0.9 1.4 4.2 1.9 0.9 1.4 6.1 6.8 0.9 1.0 0.6 0.8 0.3 1.2 0.6 0.4 0.3 1.2 0.6 0.9 14.2 0.8 0.8 0.8 0.5 1.2 17.7 21.0 67.8 37.3 16.5 15.6 17.8 20.0 18.2 10.7 19.2 21.0 0.5 0.0 0.0 16.3 0.1 0.3 0.4 0.0 0.0 64.5 0.7 0.9 0.5 0.0 0.0 0.0 29.2 0.0 0.1 0.2 0.0 0.2 0.3 0.1 0.1 0.8 0.0 0.0 26.5 0.2 0.1 0.1 0.0 0.2 1.3 0.1 1.1 0.0 0.4 69.0 54.3 0.0 0.0 0.6 0.3 0.2 0.0 0.2 5.4 1.0 0.0 10.3 2.1 15.1 5.7 0.1 0.0 0.4 0.0 0.3 0.0 0.1 0.0 33.0 0.0 1.4 0.3 9.5 17.9 0.0 0.1 0.0 0.1 1.4 0.1 0.1 TMEM159 promethin ENSG00000011638 "Transmembrane protein 159" Q96B96 16 21158377-21180616 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 128.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.2;Basal squamous epithelial cells: 176.4;Squamous epithelial cells: 127.5;Suprabasal keratinocytes: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 67.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018033, HPA063509" Approved Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA018033: AB_2204762, HPA063509: AB_2685026" "unprognostic (7.62e-3)" "unprognostic (2.42e-1)" "unprognostic (1.99e-2)" "unprognostic (1.06e-1)" "unprognostic (8.68e-2)" "unprognostic (6.80e-2)" "unprognostic (3.32e-1)" "unprognostic (2.93e-1)" "unprognostic (3.35e-1)" "unprognostic (2.93e-3)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.03e-1)" "prognostic favorable (8.11e-5)" "unprognostic (8.28e-2)" "unprognostic (1.28e-1)" "unprognostic (1.84e-2)" "unprognostic (1.57e-2)" 40.2 33.0 3.8 5.4 8.0 3.2 27.0 6.0 4.0 47.4 2.3 42.6 4.3 28.6 7.9 61.9 26.3 20.1 91.6 3.4 3.3 16.5 2.5 19.9 11.7 2.7 3.3 40.8 12.4 14.1 3.2 4.0 3.9 22.1 12.0 5.7 36.8 10.4 128.5 96.0 17.9 17.8 2.4 7.1 21.1 10.5 5.4 5.0 15.4 100.6 16.7 47.9 57.3 2.8 14.3 7.1 7.6 28.7 67.9 44.1 3.4 7.4 27.6 2.9 4.9 5.6 21.4 20.2 7.9 21.6 12.9 23.1 11.7 13.0 3.4 7.7 4.5 9.1 1.9 11.1 15.4 7.2 24.2 17.3 58.8 15.4 48.1 12.2 15.0 10.8 6.9 6.1 5.8 25.2 5.6 6.7 7.0 14.1 3.5 28.9 4.2 7.3 38.1 41.1 1.2 1.1 18.2 25.8 9.8 13.5 46.0 6.5 10.6 5.4 5.4 25.6 1.9 0.5 1.7 7.2 22.2 6.4 5.3 19.5 8.8 7.0 9.7 6.9 9.8 12.2 12.7 8.2 5.4 9.6 9.9 9.6 3.9 7.3 10.3 14.3 14.8 6.6 3.8 8.0 6.0 4.0 3.4 3.3 2.7 3.3 3.9 2.4 5.4 2.8 17.3 9.6 20.9 0.0 12.9 121.2 38.5 31.9 176.4 1.0 53.3 55.2 59.4 15.7 31.8 22.0 0.0 4.8 9.1 34.5 7.9 19.7 0.8 11.4 12.8 13.7 14.5 11.8 1.9 21.3 2.1 44.3 19.4 19.3 15.8 14.0 17.5 0.2 10.2 1.7 0.8 30.6 12.2 15.7 39.0 2.2 67.4 13.8 30.2 4.7 22.7 44.7 7.2 1.0 0.1 24.7 41.8 37.2 3.8 45.3 23.1 21.1 11.2 1.5 32.9 26.5 35.7 2.0 9.9 127.5 150.2 1.9 14.8 5.1 29.9 66.6 TMEM167A "FLJ30508, MGC23909, TMEM167" ENSG00000174695 "Transmembrane protein 167A" Q8TBQ9 5 83052846-83077863 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077278 Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA077278: " "unprognostic (5.38e-3)" "unprognostic (2.84e-3)" "unprognostic (3.78e-2)" "unprognostic (4.40e-2)" "unprognostic (1.66e-1)" "unprognostic (3.34e-1)" "unprognostic (4.06e-3)" "unprognostic (7.74e-2)" "unprognostic (9.94e-3)" "unprognostic (3.99e-3)" "unprognostic (2.72e-1)" "unprognostic (4.09e-2)" "unprognostic (2.24e-1)" "unprognostic (1.56e-1)" "unprognostic (1.51e-1)" "unprognostic (1.13e-3)" "unprognostic (1.29e-2)" 31.5 48.6 31.8 29.5 32.5 30.8 30.0 35.2 33.7 30.0 29.7 25.3 27.8 21.5 25.8 19.0 15.0 27.6 27.2 32.2 40.3 34.2 33.2 26.5 22.9 33.7 35.4 16.0 23.0 32.0 22.8 35.1 35.1 22.8 29.5 35.3 26.3 19.5 17.4 21.6 24.5 22.7 32.8 22.0 24.1 12.3 36.5 26.5 29.0 21.2 24.0 25.3 15.7 34.2 35.4 21.1 77.7 70.4 111.9 77.6 71.2 54.5 42.6 34.5 44.9 31.8 45.1 22.3 33.4 64.6 45.9 29.1 52.0 70.5 57.1 31.4 32.1 61.2 39.5 49.7 43.5 31.4 38.8 61.0 48.5 44.3 41.4 56.4 43.1 32.7 34.1 44.7 50.9 30.8 38.9 34.4 80.9 18.5 35.4 34.2 50.2 62.5 48.5 27.8 36.8 48.0 36.7 38.2 56.1 70.6 69.2 73.5 59.7 21.8 21.3 63.5 49.2 25.7 77.5 22.3 40.6 56.1 53.0 26.0 21.6 10.3 3.4 20.4 4.0 3.9 4.7 4.3 12.0 3.2 5.0 4.0 12.3 6.0 24.2 5.7 6.2 10.7 31.8 32.5 35.2 33.7 32.2 40.3 33.7 35.4 35.1 32.8 36.5 34.2 56.5 35.3 26.2 21.2 62.8 47.9 60.4 160.3 39.9 47.8 76.2 58.4 53.3 55.8 104.8 49.7 41.7 102.9 63.1 100.0 170.2 86.6 16.7 49.0 135.7 57.2 50.8 56.4 22.7 121.4 306.2 90.6 47.9 71.1 32.4 41.2 50.3 121.6 158.7 33.7 30.2 101.6 103.7 181.4 117.6 20.8 47.2 154.7 94.3 15.0 188.0 68.8 66.9 61.3 50.6 130.7 81.8 49.7 129.3 126.4 84.4 223.3 72.9 31.6 32.9 41.8 79.2 64.1 57.6 79.8 67.2 179.4 64.8 57.1 73.6 125.2 TMEM198 "MGC99813, TMEM198A" ENSG00000188760 "Transmembrane protein 198" Q66K66 2 219543663-219550595 "Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.0" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 19.2;Horizontal cells: 21.9;Muller glia cells: 10.9;Proximal enterocytes: 12.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 20.0;SH-SY5Y: 17.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042385, HPA062897" Enhanced Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA042385: AB_2677972, HPA062897: " "unprognostic (2.59e-2)" "unprognostic (8.51e-2)" "unprognostic (5.97e-3)" "unprognostic (2.77e-1)" "unprognostic (4.43e-2)" "unprognostic (8.09e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (4.28e-1)" "unprognostic (2.06e-1)" "prognostic favorable (6.89e-4)" "unprognostic (6.39e-2)" "unprognostic (7.91e-3)" "unprognostic (3.41e-3)" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.58e-1)" 3.2 8.2 10.8 1.4 9.7 0.1 3.0 12.1 19.4 4.6 2.3 2.7 8.9 5.2 1.0 2.0 3.6 1.8 4.4 21.0 8.4 4.0 4.3 3.2 0.7 7.7 7.4 14.7 12.0 3.1 18.3 1.1 6.0 4.2 0.6 2.5 3.8 1.8 2.8 1.5 4.4 1.6 7.4 2.2 4.6 5.9 8.5 0.5 4.0 2.0 0.7 3.8 2.0 8.8 0.6 0.1 5.6 9.6 1.1 1.0 4.9 2.8 1.5 2.3 2.0 12.5 1.6 2.6 2.7 1.8 5.8 3.5 2.0 1.4 0.4 8.7 2.4 2.0 2.9 10.4 1.6 0.7 4.7 2.4 0.8 1.1 2.7 2.5 0.0 1.8 7.8 8.1 1.4 1.2 0.1 0.6 7.3 1.0 0.9 0.2 3.4 2.9 1.4 1.4 20.0 17.4 0.7 2.0 5.0 1.0 0.2 4.0 0.1 2.5 1.0 2.3 1.2 7.7 2.4 2.7 2.3 0.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 10.8 9.7 12.1 19.4 21.0 8.4 7.7 7.4 6.0 7.4 8.5 8.8 0.3 0.0 1.1 2.0 0.8 0.1 1.4 1.4 1.2 9.3 3.5 4.3 1.8 4.3 0.6 0.0 2.1 1.0 0.4 0.4 1.9 3.9 0.8 0.3 2.6 0.4 19.2 0.0 4.9 7.9 0.9 3.9 1.5 0.6 0.0 1.6 0.0 1.6 0.3 21.9 4.8 2.4 2.0 0.3 0.9 1.4 2.8 0.0 1.8 0.0 0.6 10.9 0.0 3.0 1.2 1.5 4.0 4.9 1.1 0.8 12.4 1.8 0.6 7.4 0.0 1.6 2.8 8.4 4.2 0.4 0.1 2.9 0.4 5.5 0.5 0.4 TMEM231 "ALYE870, FLJ22167, JBTS20, MKS11, PRO1886" ENSG00000205084 "Transmembrane protein 231" Q9H6L2 16 75536741-75556268 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "fallopian tube: 48.5" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 52.1;Endometrial ciliated cells: 121.2;Respiratory ciliated cells: 132.2;Rod photoreceptor cells: 33.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042081 Enhanced Approved Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA042081: AB_10795391" "unprognostic (4.29e-2)" "unprognostic (9.84e-2)" "unprognostic (8.07e-2)" "unprognostic (2.71e-3)" "unprognostic (1.03e-1)" "unprognostic (9.34e-2)" "unprognostic (2.90e-2)" "unprognostic (2.81e-1)" "unprognostic (2.92e-1)" "unprognostic (1.69e-2)" "unprognostic (3.34e-3)" "unprognostic (7.84e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" "unprognostic (1.66e-1)" "unprognostic (1.12e-1)" "unprognostic (1.28e-1)" 2.4 3.3 5.1 1.4 5.1 1.4 2.5 5.0 5.2 3.6 11.9 2.5 2.4 4.2 3.6 1.7 48.5 3.2 6.0 5.3 6.5 2.9 1.1 4.6 1.6 8.8 10.3 4.7 3.1 7.0 4.9 2.2 7.1 3.5 1.9 5.2 1.5 3.5 1.0 2.3 2.6 5.5 8.5 1.5 1.9 4.5 7.3 0.9 5.8 1.2 1.0 2.6 1.7 5.1 4.0 2.6 7.1 12.0 6.8 16.6 3.8 5.0 6.3 6.1 7.3 1.4 7.0 5.0 6.7 6.9 5.1 10.3 0.8 5.3 3.9 0.9 2.9 0.3 3.6 1.6 5.9 2.9 2.1 3.7 7.0 6.2 15.1 11.0 3.3 4.5 4.8 0.2 1.8 11.5 1.8 5.2 4.0 0.8 2.1 0.9 1.0 11.5 7.4 1.6 5.7 3.8 8.8 2.5 4.4 2.3 2.3 3.0 5.1 4.7 3.7 3.0 2.6 9.1 8.4 1.6 11.9 1.3 4.6 1.8 0.3 0.2 0.6 0.4 1.5 2.2 0.7 1.2 1.0 1.0 0.6 1.0 2.5 0.4 0.2 1.3 0.2 0.6 5.1 5.1 5.0 5.2 5.3 6.5 8.8 10.3 7.1 8.5 7.3 5.1 6.4 3.2 6.3 9.4 3.0 1.0 4.7 5.5 1.8 18.3 5.3 6.1 5.2 1.5 14.0 7.3 52.1 1.1 1.1 3.7 0.0 3.0 17.6 121.2 8.1 6.3 3.0 1.7 11.6 2.3 1.2 5.2 3.6 10.6 1.3 6.1 4.2 1.5 0.9 13.5 11.4 5.0 18.3 1.2 0.8 5.3 1.8 1.5 0.0 1.0 2.8 6.0 0.0 9.5 7.6 1.5 3.8 3.8 2.0 5.0 16.8 2.1 132.2 33.1 0.0 6.6 6.1 15.3 9.8 1.8 1.0 0.3 2.3 6.0 4.2 2.5 TMEM234 "C1orf91, dJ622L5.7, FLJ90779, RP4-622L5" ENSG00000160055 "Transmembrane protein 234" Q8WY98 1 32214472-32222359 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 55.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA015049 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA015049: AB_1856409" "unprognostic (1.39e-2)" "unprognostic (1.36e-1)" "unprognostic (1.52e-1)" "unprognostic (1.26e-1)" "unprognostic (2.44e-3)" "unprognostic (3.09e-1)" "prognostic unfavorable (2.35e-5)" "unprognostic (2.67e-1)" "unprognostic (1.07e-2)" "unprognostic (6.49e-2)" "unprognostic (2.66e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.12e-5)" "unprognostic (1.95e-1)" "unprognostic (2.44e-1)" "unprognostic (7.92e-2)" "unprognostic (2.37e-2)" 6.5 7.4 5.7 2.6 5.8 2.8 6.8 5.0 6.4 7.9 7.4 6.4 2.2 7.6 9.4 9.0 7.3 3.4 9.2 5.7 6.1 9.7 6.3 6.4 3.5 5.9 6.7 9.9 5.8 6.9 12.3 5.9 6.0 8.5 4.1 6.1 7.2 7.0 3.0 4.8 5.2 4.4 5.2 7.5 5.6 9.0 5.8 3.1 12.3 1.7 3.5 6.6 7.6 5.4 10.0 7.5 4.2 4.4 12.0 9.4 4.4 14.6 10.5 7.3 5.5 5.4 9.8 3.1 16.1 13.5 5.7 8.0 5.4 10.5 6.2 6.4 5.9 6.1 11.9 6.2 8.7 7.4 4.0 11.9 10.5 7.6 5.5 12.8 10.7 3.3 5.9 1.9 12.4 3.0 2.9 6.2 7.6 2.5 5.7 4.0 3.3 3.6 16.3 5.1 5.3 5.4 10.6 5.7 5.0 13.6 2.8 2.3 12.9 2.6 4.1 10.3 10.6 3.1 1.8 1.3 8.0 2.6 9.8 25.9 11.9 19.1 5.8 13.3 9.3 6.9 4.6 6.6 11.4 6.9 3.3 4.2 35.8 10.8 9.3 8.6 3.1 6.7 5.7 5.8 5.0 6.4 5.7 6.1 5.9 6.7 6.0 5.2 5.8 5.4 7.5 9.6 1.5 10.4 8.3 2.7 6.6 14.5 5.2 5.3 9.0 9.1 3.6 4.3 11.4 23.9 2.1 26.0 5.0 17.4 1.9 20.9 27.8 17.9 9.1 7.5 6.0 7.4 10.8 15.5 23.0 9.1 16.3 10.0 3.8 10.8 6.4 5.6 19.3 1.7 7.8 11.8 10.2 8.3 3.2 55.6 9.3 8.2 14.2 8.4 11.4 8.6 9.2 3.5 2.8 18.4 12.2 7.9 5.1 5.6 12.5 11.0 23.7 13.5 6.6 5.7 9.2 31.8 15.0 5.9 3.1 21.3 6.9 15.2 9.9 8.0 TMEM248 "C7orf42, FLJ10099, FLJ13090" ENSG00000106609 "Transmembrane protein 248" Q9NWD8 7 66921225-66958551 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016495 Uncertain Approved Vesicles NA NA 1600000 "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA016495: AB_1848643" "unprognostic (6.74e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (4.64e-2)" "unprognostic (6.67e-3)" "unprognostic (9.36e-2)" "unprognostic (1.39e-2)" "unprognostic (4.14e-2)" "unprognostic (2.32e-1)" "unprognostic (4.54e-2)" "unprognostic (9.18e-2)" "unprognostic (2.80e-3)" "unprognostic (1.30e-1)" "unprognostic (8.96e-2)" "unprognostic (5.11e-2)" "unprognostic (8.28e-2)" "unprognostic (5.57e-2)" 31.8 39.7 29.2 27.5 30.8 17.8 34.8 25.3 29.0 46.6 57.5 40.8 42.4 44.3 40.6 26.6 45.0 38.6 32.4 32.2 36.1 36.3 49.4 38.7 36.5 27.3 31.0 50.0 40.3 50.0 31.7 34.5 31.0 43.1 41.1 39.0 39.6 40.9 23.1 29.5 37.4 39.2 26.3 34.2 43.6 32.6 40.1 29.5 46.1 21.4 35.0 34.0 32.4 28.0 46.4 53.3 44.2 63.4 98.2 75.0 38.7 55.7 95.1 51.8 55.9 38.9 59.2 46.7 66.3 75.5 70.8 40.8 38.3 45.9 64.0 43.1 28.2 34.2 36.9 45.4 63.5 57.6 45.5 68.0 52.4 43.6 36.1 75.4 68.5 36.1 66.6 30.6 83.4 28.1 54.3 70.5 65.9 47.5 36.1 39.3 51.4 79.3 70.3 35.1 30.7 65.6 49.1 89.0 50.6 65.6 44.8 52.1 63.9 72.4 35.4 48.0 61.9 37.2 45.4 52.1 60.6 62.9 70.5 2.3 4.0 7.7 6.0 4.3 7.2 8.3 6.5 6.4 3.2 8.1 6.3 6.8 5.8 7.3 2.7 8.3 4.7 1.9 29.2 30.8 25.3 29.0 32.2 36.1 27.3 31.0 31.0 26.3 40.1 28.0 55.1 51.3 42.7 14.7 66.2 64.5 53.5 23.6 46.7 18.5 60.6 44.2 25.0 51.5 25.2 53.3 6.2 48.3 75.2 100.8 11.7 37.0 106.2 37.8 34.5 51.7 27.6 45.9 25.8 47.2 81.2 60.9 55.5 35.0 28.5 44.8 58.2 109.9 52.7 18.5 26.4 82.6 16.2 65.7 76.5 172.3 63.6 53.0 49.8 20.6 46.2 96.7 62.8 24.1 27.7 60.2 62.3 65.8 76.5 108.8 64.4 34.3 36.9 12.7 32.9 40.3 47.7 111.5 57.9 42.2 73.9 88.1 64.4 46.4 60.3 98.7 TMEM256 "C17orf61, MGC40107" ENSG00000205544 "Transmembrane protein 256" Q8N2U0 17 7402975-7404097 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 573.1;Proximal enterocytes: 972.0;Proximal tubular cells: 801.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062732 Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA062732: AB_2684852" "unprognostic (3.82e-2)" "unprognostic (1.93e-1)" "unprognostic (2.91e-1)" "unprognostic (2.77e-2)" "unprognostic (1.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.69e-2)" "unprognostic (5.73e-2)" "unprognostic (7.45e-2)" "unprognostic (2.12e-2)" "unprognostic (3.22e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.36e-4)" "unprognostic (1.12e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.19e-2)" 92.2 84.3 63.9 22.2 66.4 36.7 86.7 67.7 73.0 85.6 63.5 72.6 76.3 63.5 48.2 74.7 77.6 24.0 99.8 62.1 65.2 122.4 173.9 51.8 34.5 67.3 64.2 75.4 113.8 42.6 45.9 14.3 67.1 81.5 25.2 15.1 60.3 24.4 67.4 64.3 90.0 17.6 67.6 67.9 91.7 12.4 64.5 30.8 51.5 41.6 28.5 69.7 67.6 72.4 67.0 89.3 47.3 64.3 78.6 99.0 43.0 30.7 43.9 49.4 46.3 36.1 38.0 59.0 54.0 31.2 39.4 56.4 29.9 93.6 35.7 30.5 99.4 37.5 32.0 95.1 54.0 13.0 49.0 87.1 44.2 64.1 53.0 66.4 73.1 63.8 28.9 39.1 64.1 36.5 44.1 42.5 21.4 29.4 58.6 69.9 41.5 68.8 121.2 28.8 5.5 37.9 47.6 36.7 51.2 46.0 66.6 23.4 43.7 22.8 42.7 46.5 39.3 32.6 45.2 31.2 60.2 18.0 44.4 12.9 63.1 14.8 35.7 48.5 44.5 77.4 42.3 41.3 59.7 69.0 48.5 45.2 3.9 39.3 36.3 82.3 46.0 77.8 63.9 66.4 67.7 73.0 62.1 65.2 67.3 64.2 67.1 67.6 64.5 72.4 103.1 44.8 55.8 0.0 134.5 87.4 93.3 100.1 94.4 24.0 212.4 216.9 62.5 131.5 76.9 132.4 8.4 77.2 78.4 162.9 297.4 132.8 6.0 80.2 84.6 85.1 125.3 100.5 0.0 190.8 223.6 83.3 88.7 84.5 68.4 50.3 114.5 573.1 205.5 20.2 0.0 186.6 81.4 164.7 128.2 6.8 137.3 108.4 144.1 0.0 166.7 134.0 88.6 0.0 0.0 171.3 214.0 71.1 173.1 87.3 972.0 801.9 96.3 42.0 59.2 80.2 160.2 10.1 39.1 179.5 134.0 46.7 91.7 64.5 210.0 90.9 TMEM263 "C12orf23, MGC17943" ENSG00000151135 "Transmembrane protein 263" Q8WUH6 12 106955719-106978778 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014453, HPA042339" Uncertain Approved Vesicles NA NA 14000 "Cluster 40: NK-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA014453: , HPA042339: AB_10795503" "unprognostic (2.56e-2)" "unprognostic (1.41e-1)" "unprognostic (8.99e-2)" "unprognostic (5.65e-2)" "unprognostic (3.90e-1)" "unprognostic (3.46e-2)" "prognostic unfavorable (7.84e-4)" "unprognostic (4.66e-2)" "unprognostic (6.01e-2)" "unprognostic (3.11e-2)" "unprognostic (7.07e-2)" "unprognostic (1.19e-1)" "unprognostic (3.05e-3)" "unprognostic (3.49e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (1.53e-1)" 20.6 27.1 14.5 20.4 15.6 7.4 22.3 14.2 18.2 41.6 21.8 17.8 17.3 28.3 33.4 9.5 16.2 30.4 28.6 15.5 22.1 29.4 44.6 15.3 21.1 13.2 17.1 29.3 23.4 20.7 37.5 43.2 16.5 28.5 19.2 16.8 21.0 21.6 11.5 8.6 15.3 29.9 13.3 16.4 30.9 19.4 21.4 31.0 33.6 14.2 19.7 22.1 13.9 13.5 32.7 28.2 54.1 37.4 125.8 141.6 23.5 123.1 114.0 59.0 74.6 30.1 14.0 3.2 37.5 174.3 33.3 14.9 34.4 48.6 80.9 61.5 38.0 45.5 41.0 65.0 65.1 2.4 28.3 98.6 23.1 63.9 53.8 137.3 73.4 35.1 22.1 12.1 83.6 26.7 35.4 21.4 17.7 21.1 60.3 77.1 41.3 7.9 60.7 27.3 28.2 38.6 67.3 31.2 51.2 41.9 36.5 13.7 86.7 50.6 30.7 66.9 31.6 50.8 31.5 30.3 39.2 7.7 79.4 11.7 1.4 1.6 15.8 1.6 18.3 15.7 15.2 13.7 4.3 16.8 26.8 24.9 1.0 19.8 0.6 14.8 17.4 13.9 14.5 15.6 14.2 18.2 15.5 22.1 13.2 17.1 16.5 13.3 21.4 13.5 31.6 9.6 23.6 12.1 33.5 0.0 52.0 0.0 53.5 24.4 47.7 25.8 55.4 22.8 11.2 23.9 31.3 40.4 54.3 12.4 92.0 19.2 34.8 19.9 75.7 26.4 28.8 10.9 15.4 33.0 72.6 61.5 50.0 32.4 29.9 33.7 33.2 44.4 13.5 11.8 16.5 65.1 0.0 6.7 0.0 37.2 47.2 10.4 0.0 22.5 9.6 34.1 22.6 24.1 8.4 17.3 13.2 43.6 68.3 48.6 23.0 47.7 12.4 21.0 26.3 39.1 41.7 51.2 22.5 12.7 0.0 36.0 36.3 30.6 16.4 44.2 TMEM270 "MGC26719, WBSCR28" ENSG00000175877 "Transmembrane protein 270" Q6UE05 7 73861159-73865890 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 215 "testis: 77.6" "Cell type enriched" "Detected in single" 7 "Endometrial ciliated cells: 2.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA077196 Approved Vesicles NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA077196: AB_2732334" "unprognostic (3.84e-2)" "unprognostic (6.91e-2)" "unprognostic (6.87e-5)" "unprognostic (1.38e-2)" "unprognostic (1.11e-2)" "unprognostic (2.81e-3)" "unprognostic (1.34e-1)" "unprognostic (8.31e-3)" "unprognostic (2.07e-1)" "unprognostic (1.66e-1)" "unprognostic (4.69e-1)" "unprognostic (2.56e-2)" "unprognostic (3.35e-2)" "unprognostic (1.26e-1)" "unprognostic (1.44e-1)" "unprognostic (7.23e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM39B FLJ10315 ENSG00000121775 "Transmembrane protein 39B" Q9GZU3 1 32072031-32102866 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040191, HPA040224" Approved Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA040191: AB_10805706, HPA040224: AB_10795274" "unprognostic (1.74e-2)" "unprognostic (2.20e-2)" "unprognostic (4.38e-2)" "prognostic unfavorable (3.00e-4)" "unprognostic (1.06e-1)" "unprognostic (1.14e-2)" "prognostic unfavorable (2.82e-6)" "unprognostic (1.10e-2)" "unprognostic (3.37e-2)" "unprognostic (1.74e-1)" "unprognostic (3.63e-2)" "unprognostic (4.47e-2)" "prognostic unfavorable (5.11e-9)" "unprognostic (2.20e-1)" "unprognostic (5.80e-2)" "unprognostic (4.45e-2)" "unprognostic (2.10e-1)" 6.3 4.5 0.8 3.7 0.6 3.8 5.5 0.4 2.6 7.9 0.2 5.8 3.3 8.9 5.5 4.5 5.7 4.4 4.3 0.8 1.1 3.9 5.1 4.7 5.8 1.0 0.8 7.2 3.5 3.6 5.1 5.0 1.0 4.6 3.5 0.6 4.4 5.6 5.2 6.2 4.6 5.8 0.6 5.1 4.5 2.5 1.1 8.4 5.0 3.4 5.4 6.4 5.6 0.8 11.4 3.4 4.6 11.7 13.3 7.7 6.3 9.1 15.7 12.2 11.8 6.9 16.6 13.7 15.5 7.7 7.7 13.1 3.4 14.6 4.0 7.0 10.9 8.2 7.9 3.6 14.8 14.1 9.0 10.7 5.9 18.3 12.7 7.0 8.7 7.9 11.5 11.5 10.4 7.5 11.1 3.9 14.6 13.1 8.7 18.0 15.1 17.0 5.8 6.9 10.6 6.3 12.9 7.7 11.4 2.0 6.2 6.7 10.5 20.5 13.3 7.3 12.0 6.1 7.8 13.0 12.4 12.7 15.4 3.7 22.1 8.4 7.8 18.9 10.6 17.7 11.8 9.7 22.8 16.1 15.2 12.6 6.2 7.7 15.0 33.9 13.8 13.9 0.8 0.6 0.4 2.6 0.8 1.1 1.0 0.8 1.0 0.6 1.1 0.8 12.3 9.6 1.1 4.9 15.3 11.1 14.6 16.2 19.4 8.4 9.7 10.3 2.7 10.0 9.2 3.7 18.8 33.4 17.6 4.7 1.9 8.3 6.7 4.9 10.9 22.0 5.4 6.5 15.8 16.0 22.0 14.1 5.1 7.0 15.2 9.8 14.6 7.0 15.5 6.7 12.3 8.2 12.2 13.5 13.9 2.2 12.2 13.7 10.6 8.4 16.9 4.9 4.1 7.1 12.2 6.3 3.4 13.9 11.4 7.1 6.0 4.4 4.6 5.8 6.6 10.8 17.0 17.4 22.2 14.7 10.2 40.8 8.5 12.6 9.6 7.5 TMEM54 CAC-1 ENSG00000121900 "Transmembrane protein 54" Q969K7 1 32894594-32901438 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 268.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1231.3;Intestinal goblet cells: 357.2;Paneth cells: 800.1;Proximal enterocytes: 418.6;Undifferentiated cells: 355.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 198.9;OE19: 242.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA060864, HPA061992" Approved Approved Vesicles NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA060864: , HPA061992: AB_2684652" "unprognostic (2.67e-1)" "unprognostic (2.57e-2)" "unprognostic (2.55e-1)" "unprognostic (4.98e-2)" "unprognostic (3.70e-2)" "unprognostic (3.85e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (2.42e-2)" "unprognostic (3.48e-2)" "unprognostic (9.43e-2)" "unprognostic (6.82e-3)" "unprognostic (2.13e-2)" "unprognostic (9.06e-2)" "unprognostic (3.12e-2)" "unprognostic (3.40e-2)" 19.2 15.6 68.2 39.9 64.2 0.0 24.6 61.3 98.4 59.0 52.8 268.0 116.0 40.4 26.6 145.3 25.5 62.0 18.7 64.1 70.0 44.3 14.9 26.8 4.6 70.5 68.8 20.3 31.8 49.5 22.6 18.4 64.8 58.2 113.2 4.2 54.0 22.9 6.9 116.0 123.1 21.3 67.8 13.2 108.0 11.9 65.5 2.4 47.8 4.9 13.0 51.1 78.6 66.4 133.3 33.9 0.0 32.0 59.1 35.4 119.9 20.0 29.2 43.1 55.2 84.7 198.9 0.0 57.1 24.8 55.2 80.0 28.6 107.4 12.8 158.3 6.4 0.2 11.3 4.5 42.9 0.4 2.0 30.5 96.2 66.1 18.1 29.1 19.3 13.0 18.7 0.1 22.7 135.6 0.1 2.6 10.3 242.7 60.8 17.7 52.2 0.6 16.2 159.8 1.8 17.1 14.4 82.1 44.0 19.3 89.3 24.2 39.9 42.3 47.5 95.9 40.8 5.2 12.4 15.8 30.1 3.3 61.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.2 64.2 61.3 98.4 64.1 70.0 70.5 68.8 64.8 67.8 65.5 66.4 6.4 19.2 27.6 3.9 6.6 20.4 92.3 36.9 20.5 8.2 82.0 61.0 4.7 97.2 36.9 47.8 4.2 42.8 1.3 1231.3 27.4 150.2 43.4 7.5 16.1 12.3 60.7 0.0 3.3 202.4 149.1 22.9 160.0 14.3 5.7 11.8 18.9 3.7 8.4 0.0 2.9 357.2 12.2 1.0 6.5 32.3 19.9 3.7 14.2 0.0 3.1 33.7 0.0 3.5 2.6 166.3 800.1 24.5 1.6 160.9 418.6 84.9 14.0 10.3 6.6 8.5 20.6 10.9 8.8 65.0 63.6 64.3 3.3 2.4 355.8 193.3 TMEM68 FLJ32370 ENSG00000167904 "Transmembrane protein 68" Q96MH6 8 55696424-55773407 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018216, HPA019173" Uncertain Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA018216: AB_2205185, HPA019173: AB_1858129" "unprognostic (4.43e-2)" "unprognostic (3.10e-2)" "unprognostic (8.04e-2)" "unprognostic (2.40e-1)" "unprognostic (4.61e-2)" "unprognostic (1.15e-1)" "unprognostic (3.46e-3)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (3.37e-2)" "unprognostic (3.28e-2)" "unprognostic (1.03e-1)" "unprognostic (3.92e-2)" "unprognostic (1.48e-2)" "unprognostic (1.64e-1)" "unprognostic (4.41e-2)" "unprognostic (1.63e-1)" 8.9 12.9 5.8 8.2 6.5 10.9 13.1 13.2 8.4 10.3 14.5 13.9 12.7 10.5 14.3 13.0 22.0 10.8 6.0 6.6 5.8 17.4 12.8 10.2 9.5 5.2 5.5 13.4 10.6 17.6 5.7 11.9 4.7 13.3 14.5 11.4 12.5 10.2 5.0 14.3 12.8 9.5 4.6 8.3 11.1 8.3 5.6 11.0 16.5 5.3 9.2 11.8 7.6 10.0 22.3 13.4 21.5 13.1 17.0 20.3 38.5 19.6 14.6 18.2 17.1 18.3 41.3 24.0 21.8 12.7 22.5 27.0 17.0 25.5 20.2 33.3 19.2 29.0 12.4 19.5 19.1 12.7 15.7 14.1 38.1 18.4 43.2 26.0 16.3 24.9 29.2 23.6 26.3 11.8 31.8 17.0 24.1 46.1 6.5 22.6 8.9 15.7 29.9 16.9 18.0 16.2 12.6 20.3 39.9 27.7 30.2 16.0 13.2 13.8 17.6 23.6 16.2 20.1 27.4 31.4 18.7 20.6 21.1 35.0 7.6 5.9 7.8 5.0 11.1 10.0 9.1 8.1 8.3 9.7 7.5 10.9 8.4 9.4 9.3 7.6 7.4 4.4 5.8 6.5 13.2 8.4 6.6 5.8 5.2 5.5 4.7 4.6 5.6 10.0 10.5 12.8 12.7 10.7 13.4 34.2 28.0 38.4 19.9 18.2 14.2 12.1 5.2 15.7 30.4 25.8 14.6 32.9 14.6 15.3 13.7 16.4 2.3 42.0 10.4 11.1 15.0 20.0 17.0 8.0 21.1 12.2 13.3 10.4 5.7 12.6 11.4 12.5 13.2 21.9 21.6 26.5 40.7 12.6 11.0 1.2 13.1 9.0 7.2 20.6 13.0 17.2 9.2 26.7 16.9 15.8 21.6 13.9 14.6 26.9 17.4 22.0 66.7 15.3 26.3 9.2 10.8 16.2 15.3 17.5 35.5 22.2 11.7 15.3 15.8 29.3 TMEM8B "C9orf127, FP588, LINC00950, NAG-5, NGX6, NGX6a" ENSG00000137103 "Transmembrane protein 8B" A6NDV4 9 35814451-35865518 "Predicted membrane proteins, Transporters" "Cell adhesion, Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 36.1;Granulosa cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 51.2" "Lineage enriched" "Detected in many" 24 "dendritic cells: 51.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052130, HPA062701" Approved Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA052130: AB_2681740, HPA062701: AB_2684839" "unprognostic (5.54e-2)" "unprognostic (3.32e-1)" "unprognostic (3.96e-1)" "unprognostic (3.53e-2)" "unprognostic (3.81e-1)" "unprognostic (1.42e-1)" "unprognostic (4.09e-2)" "unprognostic (2.67e-2)" "unprognostic (2.97e-1)" "unprognostic (1.62e-1)" "prognostic favorable (3.14e-4)" "unprognostic (5.93e-2)" "prognostic favorable (1.89e-15)" "unprognostic (8.00e-2)" "unprognostic (1.26e-1)" "unprognostic (1.68e-2)" "unprognostic (3.29e-2)" 10.4 21.1 19.9 3.1 16.0 1.8 12.3 11.5 20.7 21.7 3.6 19.9 5.1 20.1 6.2 5.7 20.8 6.7 15.9 20.3 13.9 15.8 6.4 10.2 3.6 14.2 15.3 33.6 11.8 17.8 30.6 4.5 13.9 23.9 5.5 7.7 18.1 14.2 12.8 9.3 9.5 6.9 12.7 8.5 17.7 19.1 18.5 5.2 22.7 9.6 2.6 19.3 15.7 12.4 3.1 3.4 11.7 9.2 12.9 10.7 1.4 2.8 5.5 3.1 3.8 1.4 0.8 2.5 6.5 7.7 9.1 1.2 3.1 4.7 2.5 1.9 5.2 0.7 2.5 3.4 9.1 0.2 0.2 10.1 6.1 3.2 3.4 10.0 1.8 11.5 1.2 6.9 5.5 1.2 6.6 1.4 1.6 2.7 4.6 7.2 2.4 6.2 3.3 1.5 2.8 8.1 4.3 1.8 4.1 3.8 3.2 1.1 2.9 7.3 2.2 7.2 1.1 8.6 2.8 2.8 6.7 1.2 4.6 0.7 2.1 0.2 0.5 0.1 0.3 0.6 0.4 0.4 8.2 0.5 0.4 0.4 0.9 0.7 0.1 51.2 0.2 1.3 19.9 16.0 11.5 20.7 20.3 13.9 14.2 15.3 13.9 12.7 18.5 12.4 4.4 12.8 12.2 18.9 3.3 4.5 9.1 8.1 8.0 4.1 12.1 11.4 11.7 10.0 9.1 14.7 2.1 34.1 36.1 8.2 1.9 5.7 25.4 7.7 8.4 3.2 6.7 0.8 12.4 4.0 9.2 9.2 11.2 6.3 1.3 47.3 1.8 4.0 3.2 1.7 13.0 7.0 12.2 1.3 11.2 14.0 14.6 5.3 10.6 10.3 3.6 9.1 2.1 12.1 7.2 3.6 8.0 19.5 2.6 9.0 3.0 4.5 7.5 5.3 6.6 7.1 8.7 8.6 5.2 1.9 1.6 13.0 3.6 8.1 7.8 10.0 TMTC4 "FLJ14624, FLJ22153" ENSG00000125247 "Transmembrane O-mannosyltransferase targeting cadherins 4" Q5T4D3 13 100603625-100675093 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 139.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016489, HPA057056" Approved Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA016489: AB_1858157, HPA057056: " "unprognostic (1.49e-1)" "unprognostic (1.87e-1)" "unprognostic (8.34e-2)" "unprognostic (1.35e-1)" "unprognostic (2.43e-2)" "unprognostic (1.96e-1)" "unprognostic (1.50e-2)" "unprognostic (1.96e-1)" "unprognostic (1.88e-2)" "unprognostic (1.09e-1)" "unprognostic (3.11e-1)" "unprognostic (2.34e-1)" "unprognostic (1.41e-1)" "unprognostic (1.99e-1)" "unprognostic (6.04e-2)" "unprognostic (9.18e-2)" "unprognostic (2.65e-2)" 5.2 4.2 13.4 5.9 22.9 3.1 6.5 18.9 34.0 6.9 11.5 8.4 9.9 9.6 8.0 5.1 14.3 5.7 4.0 14.0 16.0 12.5 11.3 4.3 4.8 21.6 19.4 6.1 10.5 10.7 3.3 5.0 21.9 8.7 8.5 10.0 8.7 6.0 13.6 7.4 8.6 7.0 17.9 4.3 9.2 11.8 19.1 7.1 8.1 8.7 5.7 7.7 4.6 32.2 10.4 7.7 42.2 21.2 5.7 10.5 44.6 5.5 5.0 5.0 4.1 8.1 17.5 29.6 18.4 5.0 12.0 6.8 13.5 7.8 6.6 16.9 9.3 12.6 15.4 13.0 7.1 15.7 0.4 14.7 11.1 2.2 8.8 14.8 23.5 16.1 9.5 3.7 5.7 9.2 12.5 9.0 11.3 27.8 7.8 13.9 7.7 6.8 19.8 7.4 21.1 21.9 11.1 19.7 5.3 26.0 14.6 44.6 36.6 4.8 8.2 4.1 9.7 9.5 9.1 5.8 22.4 9.9 13.5 0.0 1.1 0.1 1.3 1.2 1.1 1.0 1.3 2.1 3.3 1.2 1.5 0.5 0.0 0.7 1.8 2.3 2.1 0.8 13.4 22.9 18.9 34.0 14.0 16.0 21.6 19.4 21.9 17.9 19.1 32.2 4.7 6.4 3.9 18.9 4.5 3.1 7.2 4.2 3.4 19.0 10.7 4.1 11.3 18.6 6.2 5.5 8.4 11.6 5.6 7.7 1.9 11.6 5.8 12.2 9.7 8.4 10.7 5.0 11.1 18.7 19.8 6.2 6.1 14.4 0.0 12.8 39.7 15.3 4.3 26.9 19.4 10.1 2.0 6.9 2.5 6.2 4.1 3.7 3.6 9.4 3.3 8.2 5.2 15.1 139.6 13.0 7.4 6.8 3.6 10.9 10.5 14.2 6.8 8.6 6.6 4.2 5.8 9.7 32.3 7.9 5.8 3.1 4.1 5.3 11.7 5.3 TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 70.4;Kupffer cells: 65.4;Macrophages: 35.8;monocytes: 34.7;NK-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 29.8;HL-60: 17.6;HMC-1: 44.1;NB-4: 25.2;THP-1: 95.2;U-937: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062742 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062742: " "unprognostic (3.19e-3)" "unprognostic (1.02e-2)" "unprognostic (6.63e-3)" "unprognostic (2.27e-2)" "unprognostic (1.29e-1)" "unprognostic (6.49e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-3)" "prognostic favorable (3.64e-4)" "unprognostic (9.54e-2)" "unprognostic (3.32e-2)" "unprognostic (9.03e-2)" "prognostic unfavorable (3.53e-7)" "unprognostic (1.78e-1)" "unprognostic (3.91e-2)" "unprognostic (4.87e-2)" "unprognostic (2.23e-1)" 4.7 4.3 4.9 19.6 5.4 6.1 3.4 5.1 7.5 2.3 5.7 4.5 5.3 1.5 1.4 2.5 2.2 5.5 2.3 4.7 5.2 2.0 5.6 10.8 32.0 6.5 5.7 1.0 1.4 1.2 1.2 6.9 7.0 2.1 6.1 0.9 2.6 1.8 0.8 3.8 7.6 5.4 6.4 39.2 3.4 0.8 6.3 19.2 1.3 2.2 17.7 7.8 1.4 8.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 29.8 0.4 0.0 0.0 17.6 44.1 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.1 0.1 0.0 0.1 0.4 25.2 0.0 0.0 0.1 5.3 0.1 4.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 95.2 2.5 0.2 0.1 0.1 0.2 0.3 0.0 1.9 0.1 37.8 0.1 317.0 238.8 246.7 103.2 220.2 101.9 78.3 125.7 105.2 265.4 83.2 189.5 137.3 292.3 232.9 210.6 63.0 155.7 249.5 4.9 5.4 5.1 7.5 4.7 5.2 6.5 5.7 7.0 6.4 6.3 8.1 0.3 0.0 1.7 0.0 6.9 0.3 0.0 0.0 0.0 0.8 0.8 0.3 0.1 2.8 1.3 0.0 0.0 0.3 11.1 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 8.8 0.0 0.0 0.5 0.2 0.0 0.0 5.1 0.0 0.7 0.3 70.4 0.0 0.0 0.0 0.0 65.4 12.8 0.4 0.3 35.8 0.0 0.0 34.7 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.4 10.6 0.0 0.0 0.0 TNFSF12 "APO3L, DR3LG, TWEAK" ENSG00000239697 "TNF superfamily member 12" O43508 17 7549058-7557890 "Predicted secreted proteins" "Angiogenesis, Apoptosis, Differentiation" "Cytokine, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 115.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 17.7;BJ hTERT+: 18.4;HDLM-2: 20.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035984, HPA052967" Uncertain Approved Vesicles "Secreted to blood" NA NA 853000 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA035984: , HPA052967: AB_2682000" "unprognostic (2.96e-3)" "unprognostic (2.96e-1)" "unprognostic (4.71e-2)" "prognostic favorable (5.70e-5)" "unprognostic (5.31e-2)" "unprognostic (7.91e-2)" "unprognostic (6.45e-2)" "unprognostic (2.38e-2)" "unprognostic (4.48e-2)" "unprognostic (6.09e-2)" "unprognostic (6.20e-2)" "unprognostic (8.62e-2)" "unprognostic (3.29e-2)" "unprognostic (4.11e-2)" "unprognostic (3.15e-2)" "unprognostic (8.74e-2)" "unprognostic (2.38e-1)" 41.6 28.5 57.4 9.8 55.3 3.1 36.6 49.4 66.5 37.6 48.9 68.2 9.7 38.2 7.0 13.9 37.7 15.6 39.6 54.8 50.4 32.9 16.5 37.7 15.8 55.7 54.2 42.7 23.2 11.1 18.0 11.2 53.2 39.4 5.7 2.9 26.1 27.2 16.9 15.8 26.7 13.3 52.8 38.4 38.8 5.6 57.0 4.8 22.9 9.3 5.5 47.1 30.1 52.1 0.0 0.5 0.7 0.0 14.9 17.7 4.0 6.9 18.4 7.7 5.7 0.1 2.5 0.0 5.8 16.3 0.8 1.4 1.4 0.6 1.6 20.3 2.0 0.9 0.4 2.3 12.8 0.0 0.0 15.0 2.6 2.8 0.3 3.0 12.1 0.0 0.0 0.0 7.0 0.0 0.0 0.5 0.6 0.1 7.5 0.1 0.0 0.1 11.6 0.0 0.0 7.9 2.5 0.0 12.6 0.1 1.4 0.6 16.1 15.1 1.1 0.1 8.8 0.0 0.0 0.0 2.4 0.0 10.5 2.6 3.5 11.6 5.1 5.9 6.0 2.9 4.3 3.1 2.2 1.8 4.1 4.2 2.0 2.8 1.5 2.5 4.0 1.1 57.4 55.3 49.4 66.5 54.8 50.4 55.7 54.2 53.2 52.8 57.0 52.1 115.9 9.6 12.2 0.0 20.4 6.1 11.1 1.5 6.8 6.7 21.7 41.7 4.3 17.2 3.4 16.5 0.0 1.6 38.3 2.5 7.9 15.2 0.4 4.1 15.2 33.9 1.2 3.2 0.0 12.1 0.8 42.7 4.6 8.5 34.3 6.8 48.5 3.4 44.3 20.2 0.0 3.4 0.0 59.7 26.8 1.2 50.7 62.1 19.6 0.0 28.6 46.6 40.2 0.0 0.0 8.1 1.7 50.4 3.6 6.7 0.4 39.6 0.6 2.6 59.2 34.4 56.7 0.2 1.1 2.1 7.5 0.8 38.7 9.4 4.1 6.0 TNFSF12-TNFSF13 TWE-PRIL ENSG00000248871 "TNFSF12-TNFSF13 readthrough" 17 7549099-7561601 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 9.1;choroid plexus: 5.7" "Group enriched" "Detected in some" 17 "Alveolar cells type 2: 3.7;Club cells: 3.7;granulocytes: 3.8;Macrophages: 4.5;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 7.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.7;fHDF/TERT166: 1.3;HUVEC TERT2: 1.1;U-138 MG: 1.7;U-251 MG: 1.7" "Low region specificity" "Detected in all" "HPA004863, HPA035984, HPA052967" Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA004863: AB_1078187, HPA035984: , HPA052967: AB_2682000" "unprognostic (1.59e-1)" "unprognostic (1.48e-1)" "unprognostic (2.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "unprognostic (3.04e-1)" "unprognostic (2.19e-1)" "unprognostic (1.05e-2)" "unprognostic (1.40e-1)" "unprognostic (8.96e-3)" "unprognostic (1.38e-2)" "unprognostic (2.05e-1)" "unprognostic (8.23e-2)" 4.0 1.3 4.7 0.7 4.7 0.7 1.8 4.5 9.1 0.7 5.7 1.4 0.2 0.4 0.0 0.3 0.4 0.1 2.3 4.5 5.0 2.3 0.7 4.6 1.0 5.1 5.1 0.4 0.5 0.1 0.4 0.2 4.7 0.7 0.0 0.1 0.6 0.2 0.7 0.8 0.8 0.3 4.6 3.1 0.7 0.1 5.0 0.2 0.4 0.0 0.5 1.1 0.3 4.8 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.5 1.7 0.6 0.9 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.1 0.0 0.5 0.0 0.0 0.0 0.5 1.7 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.0 0.2 0.4 2.4 7.2 0.2 4.5 0.3 0.7 0.5 0.3 1.8 1.5 0.3 0.1 0.3 0.2 0.2 0.9 1.0 1.4 4.7 4.7 4.5 9.1 4.5 5.0 5.1 5.1 4.7 4.6 5.0 4.8 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 TNFSF14 "CD258, HVEM-L, LIGHT, LTg" ENSG00000125735 "TNF superfamily member 14" O43557 19 6661253-6670588 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 29.0;liver: 107.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 26.3;dendritic cells: 40.5;granulocytes: 26.1;Macrophages: 20.0;NK-cells: 26.8;T-cells: 43.7" "Cancer enhanced" "Detected in many" "liver cancer: 4.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 199.7" "Group enriched" "Detected in all" 4 "granulocytes: 199.7;T-cells: 61.2" "Cell line enhanced" "Detected in some" "HDLM-2: 16.9;NB-4: 4.9;THP-1: 3.1;U-937: 10.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA012700 Uncertain Approved Vesicles "Secreted to blood" NA NA 41000 "Cluster 5: Granulocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA012700: AB_1852870" "unprognostic (2.78e-3)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (2.35e-3)" "unprognostic (3.82e-4)" "unprognostic (4.51e-2)" "unprognostic (1.09e-1)" "unprognostic (2.63e-1)" "unprognostic (1.05e-2)" "unprognostic (9.23e-2)" "unprognostic (9.22e-2)" "unprognostic (3.59e-1)" "prognostic unfavorable (6.07e-13)" "unprognostic (1.09e-1)" "unprognostic (9.56e-3)" "unprognostic (1.75e-1)" "unprognostic (3.62e-2)" 29.0 1.7 2.2 3.1 1.3 1.9 2.7 0.8 6.4 2.1 1.3 2.7 1.8 0.9 0.3 1.8 9.7 1.2 3.8 1.0 1.2 1.3 107.9 4.9 2.5 1.3 1.7 5.1 4.5 0.0 1.1 0.2 1.7 2.0 1.3 0.2 2.2 0.2 0.5 0.6 5.9 1.2 0.9 3.2 2.3 0.6 3.1 1.1 2.8 0.6 2.0 4.1 2.3 1.7 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.5 0.0 0.0 0.0 16.9 0.0 0.0 0.2 1.1 0.0 0.5 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 3.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 10.4 0.0 140.9 17.6 115.3 41.8 4.0 61.2 0.4 17.7 34.5 6.9 1.9 2.8 15.0 199.7 30.7 0.5 0.7 15.9 12.8 2.2 1.3 0.8 6.4 1.0 1.2 1.3 1.7 1.7 0.9 3.1 1.7 0.7 9.6 26.3 0.0 1.6 2.9 0.7 0.9 0.0 0.0 1.1 0.8 0.8 15.7 8.2 0.0 0.0 0.1 40.5 0.0 0.0 4.1 1.2 4.8 2.6 0.9 0.0 0.4 0.1 3.8 0.2 12.4 1.1 18.1 26.1 0.2 1.8 15.8 12.8 0.0 0.1 0.2 0.0 3.4 12.3 0.0 0.3 20.0 3.6 1.0 5.8 0.0 26.8 0.0 0.1 6.0 0.0 0.0 4.8 0.6 0.0 0.4 2.8 0.0 0.0 1.4 1.0 0.2 0.3 0.3 3.3 0.0 43.7 0.0 0.0 0.4 TNPO3 "IPO12, LGMD1F, MTR10A, TRN-SR, TRN-SR2" ENSG00000064419 "Transportin 3" Q9Y5L0 7 128954180-129055173 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039555, HPA041537" Approved Enhanced Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA039555: AB_10672000, HPA041537: AB_2677539" "unprognostic (5.76e-2)" "unprognostic (1.72e-2)" "unprognostic (1.97e-1)" "unprognostic (5.49e-3)" "unprognostic (1.05e-1)" "unprognostic (1.74e-1)" "prognostic unfavorable (3.29e-5)" "unprognostic (1.86e-2)" "unprognostic (1.24e-1)" "unprognostic (1.93e-2)" "unprognostic (2.27e-2)" "unprognostic (2.34e-2)" "unprognostic (3.26e-2)" "unprognostic (4.70e-2)" "unprognostic (2.93e-1)" "unprognostic (2.04e-1)" "unprognostic (4.24e-2)" 16.1 16.9 17.1 19.3 17.7 34.3 15.7 19.0 18.7 14.1 16.3 18.4 16.4 15.6 17.8 21.1 16.2 13.0 15.6 17.3 19.9 19.1 22.9 16.0 23.4 17.0 17.6 20.5 15.1 21.1 10.0 14.8 19.3 16.6 20.1 16.5 15.5 18.0 32.6 18.1 16.6 19.5 17.2 17.7 19.7 26.4 19.0 30.1 22.8 27.0 28.8 18.6 15.1 17.6 59.1 65.3 49.7 84.3 47.3 40.5 42.3 51.8 45.0 47.4 55.5 53.7 52.9 73.3 23.6 55.7 89.7 42.3 101.6 49.8 67.6 61.3 45.0 54.0 52.2 42.2 45.0 99.8 44.2 38.1 49.7 57.9 51.4 41.4 59.9 59.5 124.7 51.3 61.2 43.7 86.9 73.4 142.6 64.4 59.7 61.0 46.3 60.0 48.0 54.6 61.5 48.7 55.2 25.7 58.3 71.4 29.0 61.3 45.2 59.7 29.4 71.1 71.5 65.3 54.6 99.3 86.3 100.5 106.1 26.7 14.1 22.0 16.4 17.3 14.6 16.1 13.3 14.8 16.1 15.5 13.0 15.2 15.5 14.5 23.9 7.7 15.1 11.7 17.1 17.7 19.0 18.7 17.3 19.9 17.0 17.6 19.3 17.2 19.0 17.6 20.4 16.0 16.7 30.7 31.4 6.8 15.6 5.7 27.3 23.4 20.3 13.8 21.4 20.0 11.6 18.4 22.9 24.7 26.9 20.4 7.9 23.2 41.4 19.1 17.7 18.8 11.5 38.5 45.8 24.8 37.2 17.4 22.4 27.7 10.8 30.5 19.6 27.9 27.8 37.0 46.8 22.2 2.0 25.7 9.5 25.4 16.8 24.9 8.8 31.9 44.4 13.6 17.5 37.7 47.5 30.3 17.7 17.7 28.5 17.6 21.7 18.7 13.1 21.7 13.1 18.5 19.4 76.3 31.8 32.5 8.2 35.0 23.5 33.1 24.8 30.4 TP53I3 PIG3 ENSG00000115129 "Tumor protein p53 inducible protein 3" Q53FA7 2 24077433-24085861 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 119.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 175.8;Late spermatids: 213.9;Proximal enterocytes: 200.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 6 "T-47d: 599.7" "Low region specificity" "Detected in all" "CAB017479, HPA022012, HPA028742" Enhanced Supported Vesicles NA NA 250000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB017479: AB_2303667, HPA022012: AB_1858202, HPA028742: AB_10603456" "unprognostic (3.66e-2)" "unprognostic (1.41e-3)" "unprognostic (5.55e-2)" "unprognostic (8.04e-2)" "unprognostic (7.10e-3)" "unprognostic (4.47e-1)" "unprognostic (1.09e-2)" "unprognostic (1.53e-3)" "unprognostic (1.17e-1)" "unprognostic (2.83e-2)" "unprognostic (3.52e-2)" "unprognostic (1.75e-1)" "unprognostic (9.89e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-1)" "unprognostic (3.67e-2)" "unprognostic (8.57e-3)" 20.2 24.6 8.6 16.1 9.8 20.0 17.2 8.4 9.6 29.6 11.2 54.4 51.5 17.3 4.5 119.2 16.5 26.3 15.4 7.5 9.0 46.8 15.2 29.9 7.2 9.4 11.1 8.2 40.1 7.0 11.7 10.6 8.5 15.0 40.8 2.0 25.3 11.2 6.2 8.0 69.1 16.9 7.7 11.9 25.3 38.4 13.0 14.2 23.6 5.9 10.1 22.3 63.8 9.7 27.5 86.8 50.6 21.1 38.8 85.3 37.2 27.3 32.3 22.6 31.1 22.1 48.4 3.5 15.0 44.0 6.1 8.0 13.1 46.5 13.8 21.6 2.0 8.7 33.3 57.5 25.2 4.1 15.3 92.3 72.3 60.2 14.7 46.1 102.0 16.3 7.3 23.4 95.5 18.1 5.0 0.6 39.2 30.8 36.0 10.1 45.7 0.9 38.1 41.4 7.2 32.9 35.1 7.8 6.1 40.5 599.7 5.6 80.6 26.9 63.8 18.5 13.7 10.6 7.4 3.0 8.9 0.4 7.0 11.8 19.1 16.9 0.2 12.6 0.2 4.9 0.2 0.6 16.0 5.5 0.1 0.4 4.1 0.3 5.6 7.1 0.5 6.1 8.6 9.8 8.4 9.6 7.5 9.0 9.4 11.1 8.5 7.7 13.0 9.7 19.2 28.9 38.4 3.9 6.8 4.7 24.7 69.7 6.8 0.8 25.8 33.0 9.0 50.1 51.9 42.3 0.0 41.9 1.1 175.8 109.5 93.5 127.8 50.4 47.4 20.3 79.4 7.2 0.4 134.7 31.9 30.6 83.6 68.2 12.7 85.8 23.9 12.9 45.0 0.0 0.4 63.9 57.0 22.9 11.1 213.9 7.8 20.9 14.2 4.7 23.9 9.5 0.0 5.0 0.3 91.1 138.5 9.1 8.0 11.4 200.9 104.7 19.2 1.9 19.7 14.1 36.8 56.6 14.3 38.8 7.0 28.9 3.4 16.2 75.2 49.9 TPK1 "HTPK1, PP20" ENSG00000196511 "Thiamin pyrophosphokinase 1" Q9H3S4 7 144451941-144836395 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 14.3" "Cell type enhanced" "Detected in many" "Early spermatids: 83.0;Excitatory neurons: 82.6;Inhibitory neurons: 76.3;Late spermatids: 95.8;Microglial cells: 110.5" "Cancer enhanced" "Detected in many" "renal cancer: 3.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 70.6;CACO-2: 17.2;EFO-21: 21.2;TIME: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021545, HPA021849" Approved Approved Vesicles NA NA 210000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA021545: AB_1858209, HPA021849: AB_1858210" "unprognostic (4.05e-2)" "unprognostic (3.28e-2)" "unprognostic (2.38e-2)" "unprognostic (3.32e-2)" "unprognostic (2.42e-1)" "unprognostic (1.63e-1)" "unprognostic (7.62e-2)" "unprognostic (6.08e-2)" "unprognostic (2.37e-1)" "unprognostic (1.68e-1)" "unprognostic (3.76e-2)" "unprognostic (6.06e-2)" "unprognostic (1.45e-3)" "unprognostic (3.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.59e-1)" "unprognostic (9.22e-3)" 4.3 3.4 2.9 5.9 3.2 2.7 4.2 2.1 4.1 2.7 3.3 6.4 14.3 2.2 1.5 1.9 2.0 3.6 3.4 2.8 5.2 3.9 4.5 5.2 5.8 3.1 3.0 2.3 2.0 1.8 1.5 5.2 3.0 1.8 6.1 2.4 3.6 2.6 1.6 1.4 7.5 3.6 2.9 8.1 2.2 3.4 4.3 2.8 3.1 2.9 5.0 4.1 1.6 3.9 0.7 0.7 0.7 70.6 0.5 0.7 5.8 0.3 0.3 0.2 0.2 17.2 2.8 1.3 21.2 1.2 1.4 0.0 1.4 0.8 0.6 4.3 1.0 0.3 0.2 0.3 1.8 5.5 1.7 1.4 1.4 0.8 1.0 2.0 13.6 2.8 1.5 3.2 0.3 2.1 1.6 8.2 1.8 2.1 5.9 0.7 1.6 2.5 10.9 6.3 0.7 0.2 1.1 0.2 1.3 1.3 1.0 10.4 16.3 0.7 1.8 1.3 0.9 1.6 4.2 1.7 2.5 13.8 0.7 0.4 10.2 0.3 5.0 7.4 5.2 6.7 5.5 4.6 13.2 7.2 6.5 5.4 4.7 5.8 10.8 3.1 7.7 5.6 2.9 3.2 2.1 4.1 2.8 5.2 3.1 3.0 3.0 2.9 4.3 3.9 8.5 9.6 2.8 43.1 23.8 2.3 2.6 3.0 0.6 3.9 4.4 2.9 5.9 8.6 1.3 3.7 8.4 41.2 8.3 20.1 19.6 4.3 83.0 5.3 2.3 8.9 1.2 2.1 82.6 6.7 14.3 6.3 7.1 8.6 7.6 6.5 6.1 5.2 17.0 1.7 76.3 5.0 0.0 18.9 19.2 95.8 5.0 17.9 8.8 110.5 15.7 3.4 17.5 55.8 38.4 9.8 15.9 1.2 9.9 1.8 20.4 8.6 3.2 5.4 0.0 3.6 2.9 14.9 10.5 2.1 1.7 32.0 12.1 4.0 8.1 4.1 TPRA1 "FLJ32197, GPR175, TMEM227, TPRA40" ENSG00000163870 "Transmembrane protein adipocyte associated 1" Q86W33 3 127571232-127598267 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 179.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019784 Approved Approved Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "HPA019784: AB_2670266" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (9.41e-3)" "unprognostic (1.66e-2)" "unprognostic (6.91e-3)" "unprognostic (9.74e-2)" "prognostic unfavorable (6.46e-4)" "unprognostic (3.46e-1)" "unprognostic (2.32e-1)" "unprognostic (1.91e-1)" "unprognostic (1.17e-1)" "unprognostic (1.11e-1)" "unprognostic (2.02e-2)" "unprognostic (1.73e-2)" "unprognostic (4.42e-2)" "unprognostic (2.09e-1)" "unprognostic (4.28e-2)" 23.9 29.7 22.4 11.7 23.3 26.5 24.5 23.4 26.2 35.8 25.9 25.8 16.9 28.8 12.5 26.4 28.1 16.5 24.7 22.3 23.3 26.8 37.0 24.9 13.9 22.9 23.4 27.8 26.7 29.0 21.7 20.8 23.0 28.8 11.3 8.0 26.4 16.2 26.8 42.9 21.2 17.2 22.7 25.0 25.8 16.3 24.2 11.5 27.0 19.8 13.0 28.5 28.8 22.7 40.0 31.2 12.9 27.3 51.4 28.6 42.1 20.5 34.2 24.7 22.2 22.1 30.9 36.7 37.6 38.4 77.2 43.6 22.6 34.8 12.9 20.0 15.0 21.4 46.0 20.7 56.6 13.3 44.7 28.8 28.8 16.4 42.8 51.2 18.0 24.5 14.0 36.7 30.4 39.8 18.5 43.4 19.3 25.5 23.4 31.9 17.0 37.0 29.6 19.1 24.6 9.5 37.7 57.7 35.1 10.4 27.3 42.3 28.7 29.6 13.1 60.0 13.2 25.0 21.0 34.4 31.9 38.8 22.4 3.8 12.9 11.5 6.4 9.4 8.6 6.6 7.4 9.5 12.7 6.4 5.6 6.8 7.0 6.6 8.4 9.7 7.2 6.5 22.4 23.3 23.4 26.2 22.3 23.3 22.9 23.4 23.0 22.7 24.2 22.7 15.7 22.4 7.0 13.1 11.7 50.0 20.5 18.8 24.5 7.8 16.3 17.9 11.8 11.5 16.5 25.8 4.2 56.9 8.4 18.2 5.9 29.1 2.7 23.5 18.0 22.8 17.4 46.5 9.3 19.6 43.3 22.9 17.9 27.5 17.8 13.9 21.8 21.7 32.9 5.0 9.7 18.7 18.3 16.0 179.7 2.4 33.5 32.0 30.2 5.6 52.3 11.2 20.6 6.6 8.1 31.4 17.6 19.5 17.9 37.5 37.5 13.1 12.4 8.9 13.1 13.2 18.3 8.4 17.9 19.1 54.4 68.1 12.6 12.7 20.7 23.5 TRAF3IP3 T3JAM ENSG00000009790 "TRAF3 interacting protein 3" Q9Y228 1 209756032-209782320 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 130.5" "Cell type enhanced" "Detected in many" "B-cells: 133.8;dendritic cells: 124.7;NK-cells: 407.8;T-cells: 162.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 115.2;JURKAT: 64.2;Karpas-707: 46.2;MOLT-4: 60.9;NB-4: 68.7;THP-1: 64.1;U-266/70: 68.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040796 Enhanced Approved Vesicles NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040796: AB_10794861" "prognostic favorable (4.11e-4)" "unprognostic (1.11e-1)" "unprognostic (1.51e-3)" "unprognostic (1.36e-4)" "unprognostic (2.67e-1)" "unprognostic (1.91e-5)" "unprognostic (3.83e-3)" "prognostic favorable (8.15e-4)" "unprognostic (5.30e-2)" "unprognostic (3.72e-2)" "unprognostic (5.00e-2)" "unprognostic (2.39e-1)" "unprognostic (1.38e-4)" "unprognostic (3.08e-1)" "unprognostic (2.93e-2)" "unprognostic (3.16e-2)" "unprognostic (4.21e-2)" 3.6 2.3 1.9 51.6 2.0 31.8 4.1 1.8 4.2 3.5 1.4 8.2 7.4 2.8 2.7 3.4 2.0 10.5 1.7 2.0 2.0 4.2 5.7 10.8 99.7 3.0 2.6 2.1 0.9 0.7 0.8 2.0 3.0 3.4 10.4 0.3 5.6 2.8 1.1 2.4 30.6 3.8 2.3 60.1 13.4 3.8 3.0 130.5 3.0 1.9 90.5 11.7 2.2 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 115.2 0.0 11.0 0.0 0.0 0.2 17.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 64.2 0.1 46.2 0.0 0.0 60.9 68.7 0.2 0.0 0.0 7.1 0.0 20.8 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 64.1 0.0 0.0 0.1 0.0 0.1 68.1 25.6 4.7 0.0 31.9 0.1 456.2 155.3 169.6 296.7 171.1 317.7 300.5 410.4 343.1 164.1 287.8 459.3 365.0 41.2 345.1 209.8 121.6 587.1 414.3 1.9 2.0 1.8 4.2 2.0 2.0 3.0 2.6 3.0 2.3 3.0 3.7 1.6 3.2 9.6 0.3 133.8 2.3 4.8 1.2 1.2 1.7 1.5 1.9 0.7 2.8 0.2 0.0 0.0 0.5 124.7 0.4 11.7 0.1 11.3 14.8 0.9 2.1 0.0 22.9 0.4 0.2 0.3 1.4 2.0 48.0 58.2 0.0 6.1 3.8 22.3 0.0 0.4 0.4 0.0 24.7 12.6 9.0 0.3 40.8 10.6 39.4 69.8 0.2 407.8 0.0 0.7 0.0 0.1 0.0 64.1 2.4 0.4 12.8 0.9 0.4 0.0 0.7 1.2 8.0 0.6 2.6 2.3 0.4 162.8 0.0 0.6 1.8 TRAPPC5 "MGC52424, TRS31" ENSG00000181029 "Trafficking protein particle complex 5" Q8IUR0 19 7680833-7687703 "Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 57.5;Gastric mucus-secreting cells: 86.2;Plasma cells: 76.9;Squamous epithelial cells: 80.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 314.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042221, HPA049064" Uncertain Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Vesicles "HPA042221: AB_2677907, HPA049064: AB_2680618" "unprognostic (3.10e-2)" "unprognostic (5.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.12e-2)" "unprognostic (1.14e-1)" "unprognostic (3.21e-3)" "unprognostic (1.80e-1)" "unprognostic (2.86e-1)" "unprognostic (6.28e-2)" "unprognostic (2.55e-2)" "unprognostic (2.12e-2)" "unprognostic (6.82e-2)" "unprognostic (4.86e-8)" "unprognostic (3.09e-1)" "unprognostic (1.11e-1)" "unprognostic (6.08e-2)" "unprognostic (1.51e-1)" 58.9 86.8 65.7 25.6 68.7 62.7 58.4 67.1 112.6 55.6 60.6 53.0 27.6 52.1 8.1 85.6 44.7 13.8 105.1 69.4 74.7 75.7 99.7 35.9 23.4 64.5 68.9 50.1 67.1 19.9 58.4 19.1 70.5 71.1 8.4 9.0 64.8 17.2 112.4 90.6 48.5 11.5 64.3 60.6 57.5 181.4 65.9 16.8 56.0 27.3 12.2 55.5 56.2 64.4 61.0 129.4 20.7 56.9 16.3 24.1 62.1 47.1 33.8 45.3 46.1 76.9 41.2 62.9 92.0 32.7 25.8 55.2 13.0 47.2 8.9 48.3 199.2 23.7 86.7 163.7 56.8 42.1 45.3 40.0 61.9 34.6 15.8 15.4 57.6 64.3 34.3 89.3 22.3 190.7 72.3 148.8 66.1 27.1 314.1 46.6 28.8 91.1 50.7 142.8 54.1 47.0 40.1 74.6 69.1 7.1 60.1 44.3 58.8 54.2 44.9 103.3 47.7 80.8 44.2 44.3 75.3 51.2 74.2 207.5 373.4 151.4 116.7 394.1 112.3 313.7 145.0 129.3 442.0 289.2 141.7 124.7 518.4 97.4 365.5 188.8 222.5 329.3 65.7 68.7 67.1 112.6 69.4 74.7 64.5 68.9 70.5 64.3 65.9 64.4 1.8 3.2 3.6 15.3 36.1 1.9 1.2 2.4 57.5 5.1 6.3 4.2 1.0 1.5 5.1 5.5 2.1 3.5 1.2 26.7 0.0 26.9 13.3 3.8 4.8 5.6 11.4 41.0 13.5 19.3 5.3 14.3 86.2 3.7 1.3 2.0 8.2 13.4 9.9 8.4 16.4 15.7 0.0 18.8 3.3 44.4 1.5 52.2 1.8 11.2 17.0 1.5 4.1 11.6 22.8 19.8 26.3 3.4 76.9 1.9 28.0 9.2 2.6 4.8 0.0 1.4 8.4 5.0 1.2 80.1 1.7 3.4 18.0 2.7 14.1 1.5 TRIM17 "RBCC, RNF16, terf" ENSG00000162931 "Tripartite motif containing 17" Q9Y577 1 228407935-228416861 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 42.0" "Group enriched" "Detected in some" 27 "Early spermatids: 291.1;Late spermatids: 87.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 4.4;HEL: 2.1;NTERA-2: 1.9;SH-SY5Y: 2.3;T-47d: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA054908 Approved Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA054908: AB_2682638" "prognostic favorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (3.06e-2)" "unprognostic (5.45e-2)" "unprognostic (1.25e-1)" "unprognostic (7.74e-3)" "unprognostic (7.42e-3)" "unprognostic (2.02e-1)" "unprognostic (1.17e-2)" "unprognostic (8.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.04e-1)" "unprognostic (5.96e-4)" "unprognostic (3.88e-1)" "unprognostic (4.88e-2)" "unprognostic (6.33e-2)" "unprognostic (3.64e-1)" 2.1 1.2 3.2 0.3 6.3 0.2 2.9 10.2 4.9 3.0 1.1 0.6 0.2 2.0 0.4 1.9 3.9 0.4 1.7 4.8 1.4 3.0 0.2 1.5 0.6 1.3 0.9 3.2 0.6 1.6 2.1 0.3 0.8 4.1 0.0 0.2 4.6 0.7 0.1 2.2 1.0 0.2 0.0 6.4 1.0 42.0 2.6 0.0 3.1 0.0 0.2 1.6 3.2 1.0 0.1 0.4 0.2 0.2 0.0 0.0 4.4 0.3 0.0 0.0 0.0 1.0 0.5 0.0 1.0 0.0 0.1 1.1 0.0 0.0 0.1 0.1 0.4 2.1 0.7 0.1 0.8 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.3 0.0 0.1 0.2 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.3 2.3 0.0 0.2 0.0 0.4 5.6 0.1 0.0 0.2 0.9 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 3.2 6.3 10.2 4.9 4.8 1.4 1.3 0.9 0.8 0.0 2.6 1.0 0.0 0.0 0.5 0.3 0.1 0.3 1.7 0.1 2.8 1.0 0.6 0.9 1.5 0.0 1.5 1.8 0.0 0.0 0.9 0.1 0.0 0.7 291.1 1.2 1.3 0.3 0.0 0.0 7.0 0.0 0.0 1.1 0.0 0.8 0.0 0.3 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 87.9 1.2 0.1 0.0 1.0 0.0 0.5 1.0 0.5 0.9 0.6 0.0 0.4 0.1 0.7 0.0 0.0 2.4 0.0 0.0 0.1 0.3 2.5 1.8 0.2 0.3 0.8 0.9 0.0 0.0 0.6 TRPC1 HTRP-1 ENSG00000144935 "Transient receptor potential cation channel subfamily C member 1" P48995 3 142724034-142807888 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Astrocytes: 93.7;Excitatory neurons: 144.6;Granulosa cells: 91.8;Inhibitory neurons: 184.4;Microglial cells: 49.6;Oligodendrocyte precursor cells: 154.8;Oligodendrocytes: 164.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 23.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009387, HPA021130" Supported Approved Vesicles NA NA "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Vesicles "CAB009387: AB_2240941, HPA021130: AB_1858361" "unprognostic (1.66e-1)" "unprognostic (7.38e-2)" "unprognostic (1.56e-2)" "unprognostic (4.37e-5)" "unprognostic (5.53e-1)" "unprognostic (1.40e-2)" "unprognostic (5.90e-3)" "unprognostic (1.59e-2)" "unprognostic (1.36e-1)" "unprognostic (2.17e-1)" "unprognostic (8.46e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (2.72e-5)" "unprognostic (1.44e-3)" "unprognostic (1.57e-1)" "unprognostic (1.61e-1)" "unprognostic (2.49e-2)" 5.2 4.7 7.3 1.9 7.9 0.3 4.7 10.9 7.5 9.1 5.8 7.6 1.2 11.1 5.2 3.6 8.6 5.4 10.1 7.9 7.0 3.2 0.8 3.3 1.9 7.1 5.6 14.2 1.4 6.5 10.3 3.5 7.7 7.0 2.5 22.8 2.9 7.8 1.2 3.6 3.9 10.6 6.1 2.8 3.2 4.8 6.1 1.5 5.1 3.6 1.0 6.3 6.9 7.9 4.2 5.7 10.8 1.2 9.7 23.9 4.8 6.8 10.5 8.4 12.2 1.7 1.1 0.0 2.1 7.0 14.2 0.3 3.0 3.2 12.2 1.0 4.1 6.8 2.6 2.9 4.0 0.4 0.0 11.4 3.2 7.9 9.4 14.2 4.9 0.0 0.2 0.0 12.1 2.6 0.4 0.5 6.0 0.1 3.1 0.0 5.0 0.0 5.9 0.1 6.7 4.8 8.1 0.0 1.5 9.9 3.3 0.1 4.3 10.1 1.6 14.0 9.1 3.9 1.8 2.1 7.7 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.3 7.9 10.9 7.5 7.9 7.0 7.1 5.6 7.7 6.1 6.1 7.9 6.2 3.2 0.5 93.7 2.9 2.9 1.6 1.2 7.4 17.9 0.9 1.8 12.0 1.5 0.6 5.5 16.7 0.2 0.3 0.0 0.0 0.3 3.6 0.5 10.8 4.6 1.8 0.4 144.6 0.2 0.2 13.2 0.0 0.9 0.0 91.8 3.6 0.0 0.1 13.5 184.4 0.0 0.0 0.0 1.6 2.9 8.4 0.5 1.8 49.6 0.1 7.7 0.0 154.8 164.8 0.1 0.0 10.9 1.5 0.9 0.0 0.7 3.0 16.0 0.0 10.4 12.0 9.8 2.8 0.7 1.1 0.3 2.2 1.7 0.0 0.3 TRPM3 "GON-2, KIAA1616, LTRPC3" ENSG00000083067 "Transient receptor potential cation channel subfamily M member 3" Q9HCF6 9 70529060-71446904 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "choroid plexus: 801.0" "Cell type enhanced" "Detected in many" "Astrocytes: 905.0;Excitatory neurons: 390.3;Inhibitory neurons: 186.9;Muller glia cells: 184.5" "Cancer enhanced" "Detected in single" "renal cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HAP1: 17.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA072650, HPA074393" Enhanced Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA072650: , HPA074393: " "unprognostic (3.74e-1)" "unprognostic (6.30e-2)" "unprognostic (4.79e-2)" "unprognostic (4.81e-2)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.19e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-2)" "unprognostic (6.10e-2)" "unprognostic (1.15e-2)" "unprognostic (1.82e-7)" "unprognostic (3.51e-2)" "unprognostic (5.64e-2)" "unprognostic (1.74e-2)" "unprognostic (1.50e-2)" 0.7 0.6 22.0 0.1 30.4 0.2 0.1 40.5 9.6 1.0 801.0 0.2 0.8 1.1 1.3 0.1 0.4 0.4 0.8 39.3 27.8 16.5 0.2 0.1 0.1 36.7 46.8 3.6 0.5 0.0 2.9 0.1 20.8 0.5 0.1 23.0 0.1 2.5 0.3 0.1 0.0 0.2 25.2 0.3 0.6 5.1 41.6 0.2 0.9 0.1 0.0 0.1 0.4 15.4 0.0 0.0 0.9 0.0 1.1 2.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 17.2 0.0 0.1 0.0 0.1 0.1 1.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 2.3 0.2 0.0 0.0 1.0 4.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.9 0.0 1.1 0.0 0.2 0.0 0.3 0.2 0.0 0.0 3.1 0.0 0.1 3.1 0.0 0.0 0.0 0.0 0.4 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 22.0 30.4 40.5 9.6 39.3 27.8 36.7 46.8 20.8 25.2 41.6 15.4 0.3 3.2 3.0 905.0 0.5 0.4 0.9 0.0 0.6 16.4 0.3 0.5 5.3 5.7 2.5 16.5 66.7 0.1 0.2 0.1 5.9 0.1 4.8 1.4 1.0 1.3 15.4 0.0 390.3 0.2 0.1 3.0 0.0 3.2 0.0 1.4 0.7 0.3 0.2 1.7 186.9 0.1 0.0 0.9 1.4 2.3 5.6 0.8 0.0 56.2 0.2 184.5 1.0 105.6 8.3 0.1 0.1 9.1 0.0 0.5 0.1 33.3 0.8 10.1 0.0 3.5 1.3 1.3 0.6 0.0 0.9 0.3 0.9 0.6 0.0 0.3 TRUB1 PUS4 ENSG00000165832 "TruB pseudouridine synthase family member 1" Q8WWH5 10 114938195-114977676 "Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 62.2;Theca cells: 74.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037914, HPA057552" Approved Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA037914: AB_10672399, HPA057552: AB_2683465" "unprognostic (1.98e-1)" "unprognostic (1.91e-2)" "unprognostic (1.27e-2)" "unprognostic (2.93e-2)" "unprognostic (3.20e-3)" "unprognostic (9.79e-2)" "unprognostic (9.26e-2)" "unprognostic (4.89e-2)" "unprognostic (6.87e-2)" "unprognostic (2.51e-2)" "unprognostic (2.26e-2)" "unprognostic (1.56e-1)" "unprognostic (1.50e-3)" "unprognostic (7.54e-2)" "unprognostic (2.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.09e-1)" 7.4 29.3 6.3 7.5 7.4 4.2 11.3 5.1 9.0 9.8 7.3 9.5 8.9 12.8 9.3 8.3 9.7 7.7 21.5 7.6 7.1 16.0 12.9 6.6 10.0 5.8 6.0 16.8 6.8 15.8 4.9 7.5 6.1 11.7 10.4 6.7 9.3 9.9 7.5 6.5 8.2 11.1 5.6 9.3 8.7 17.9 7.0 11.5 12.3 9.7 10.1 7.8 4.8 6.4 25.5 19.6 18.8 47.0 13.3 17.7 25.3 21.4 24.1 28.4 32.0 16.1 25.5 31.4 24.2 16.9 12.4 21.3 25.6 26.5 41.8 23.9 27.5 14.4 9.2 28.8 22.8 27.2 20.7 18.2 35.8 20.2 39.6 30.1 16.2 24.9 15.1 12.5 34.1 12.3 25.7 21.6 17.8 17.0 19.1 25.4 47.5 19.2 37.4 12.7 17.5 19.3 18.0 26.4 47.7 20.0 21.1 16.6 14.5 13.0 13.0 20.8 26.5 23.6 20.4 26.3 18.3 34.2 11.9 4.0 2.6 0.9 4.4 4.0 6.5 7.3 4.7 4.7 4.8 5.9 6.2 5.8 0.2 8.1 7.3 4.3 6.2 4.6 6.3 7.4 5.1 9.0 7.6 7.1 5.8 6.0 6.1 5.6 7.0 6.4 6.9 12.8 8.4 8.8 11.2 5.6 4.7 15.3 6.2 13.9 11.9 8.1 13.6 4.3 12.0 9.2 2.1 9.1 10.5 7.1 21.5 7.6 62.2 11.1 12.8 6.6 7.7 9.0 23.0 4.9 6.6 11.2 6.6 12.0 10.2 26.7 12.1 20.2 7.6 25.2 22.0 8.2 6.1 7.3 4.2 9.6 8.4 5.0 3.6 8.4 5.4 10.4 9.2 31.2 16.7 7.0 3.6 10.1 12.7 4.2 6.2 27.9 9.8 5.6 6.6 8.4 9.3 14.5 23.3 15.9 7.0 6.2 8.0 74.1 12.9 5.8 TSPAN11 ENSG00000110900 "Tetraspanin 11" A1L157 12 30926428-30996602 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 25.9" "Cell type enhanced" "Detected in some" "Hepatic stellate cells: 5.7;Inhibitory neurons: 5.7;Late spermatids: 10.6;Oligodendrocyte precursor cells: 27.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.2;HSkMC: 22.8;NTERA-2: 18.2;SCLC-21H: 9.7;SH-SY5Y: 18.6;SuSa: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066789 Approved Vesicles NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA066789: AB_2685723" "unprognostic (4.10e-2)" "unprognostic (4.27e-2)" "unprognostic (4.38e-3)" "unprognostic (1.18e-2)" "unprognostic (4.51e-1)" "prognostic favorable (5.28e-4)" "unprognostic (4.28e-2)" "prognostic favorable (3.43e-4)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (1.51e-2)" "unprognostic (3.03e-2)" "unprognostic (5.77e-3)" "unprognostic (2.04e-2)" "unprognostic (5.81e-2)" "unprognostic (2.90e-3)" "unprognostic (1.79e-1)" 2.5 2.1 5.5 7.5 5.1 0.0 1.9 9.3 5.0 6.5 0.8 25.9 3.9 1.7 5.8 3.5 1.9 7.1 6.5 5.0 3.9 1.0 0.7 3.4 2.2 4.5 5.7 0.8 1.1 0.1 1.0 0.7 3.7 4.1 8.8 1.4 2.4 4.8 0.4 5.6 9.6 6.4 2.3 2.4 3.8 1.0 6.3 0.8 3.1 1.2 4.1 4.5 3.6 4.8 0.0 0.3 25.2 0.0 0.1 0.3 0.2 0.3 0.8 0.0 0.0 0.0 0.8 0.0 1.4 2.2 0.1 0.6 0.3 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.1 22.8 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.0 18.2 0.0 0.2 0.1 0.1 0.5 0.0 0.1 9.7 18.6 0.2 0.0 0.1 11.2 0.0 0.0 0.0 0.1 1.2 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.1 9.3 5.0 5.0 3.9 4.5 5.7 3.7 2.3 6.3 4.8 0.6 0.0 0.0 3.6 0.0 0.8 0.0 0.0 0.0 1.7 0.1 0.0 2.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.5 2.4 3.3 0.0 0.0 1.5 0.0 0.0 4.3 0.0 0.4 0.0 0.2 5.7 0.2 0.1 0.0 5.7 0.0 0.0 0.0 1.7 10.6 4.7 0.2 1.8 1.0 0.0 3.6 0.0 27.2 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.9 0.5 0.0 0.3 1.1 0.2 0.5 0.1 1.1 0.0 0.2 0.1 0.0 0.1 TSPAN14 "DC-TM4F2, MGC11352, TM4SF14" ENSG00000108219 "Tetraspanin 14" Q8NG11 10 80454166-80533124 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 156.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 276.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014773, HPA057174" Uncertain Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA014773: AB_2208670, HPA057174: " "unprognostic (7.52e-2)" "prognostic favorable (3.56e-4)" "unprognostic (6.55e-3)" "unprognostic (1.56e-1)" "unprognostic (4.40e-2)" "unprognostic (1.18e-1)" "unprognostic (2.11e-2)" "unprognostic (8.90e-2)" "unprognostic (5.21e-2)" "unprognostic (3.13e-1)" "unprognostic (5.15e-3)" "unprognostic (4.12e-3)" "prognostic favorable (4.20e-4)" "unprognostic (2.52e-2)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "unprognostic (2.57e-3)" 97.9 20.7 29.1 43.1 24.2 57.2 80.1 25.1 29.7 63.1 19.4 33.4 30.9 38.4 44.1 92.1 47.1 32.9 51.2 26.2 21.4 45.7 21.1 70.8 54.2 31.7 32.2 47.2 33.1 35.7 15.7 81.9 29.7 34.8 27.1 7.9 47.7 34.1 24.9 74.3 34.8 33.3 31.2 48.5 24.7 23.2 32.8 40.1 46.5 42.1 44.6 55.0 56.1 31.4 96.2 135.6 128.3 44.5 186.6 59.3 59.6 49.3 91.8 51.1 38.0 134.8 54.6 31.5 93.2 26.4 18.9 97.0 35.9 88.5 41.4 55.9 13.9 88.9 15.8 118.2 63.5 31.8 20.3 58.8 77.2 52.8 92.1 94.8 191.5 31.8 48.8 23.0 15.0 83.3 50.0 23.3 29.5 61.2 0.1 167.9 14.9 5.3 203.9 131.9 27.5 42.3 19.7 133.7 149.5 43.7 54.1 79.8 276.3 13.0 52.8 12.4 35.1 10.7 42.0 11.8 42.2 65.4 57.5 16.2 51.5 56.3 92.1 102.1 41.3 13.8 70.7 81.1 33.9 13.7 82.3 79.3 54.7 95.2 172.8 13.6 61.8 84.3 29.1 24.2 25.1 29.7 26.2 21.4 31.7 32.2 29.7 31.2 32.8 31.4 141.9 16.0 55.1 13.1 18.5 34.9 40.3 54.6 35.3 2.1 29.5 23.2 11.3 25.8 39.0 33.1 77.2 7.8 38.4 32.8 7.9 43.8 2.4 44.7 38.9 95.3 64.2 35.6 12.9 24.8 74.4 18.8 18.3 75.1 7.6 41.2 156.7 21.1 50.5 3.3 7.4 37.0 34.6 129.3 12.9 4.1 39.1 66.5 14.2 35.6 51.8 23.7 89.6 4.5 13.5 64.2 21.6 41.0 18.4 55.7 23.4 8.0 29.6 7.1 98.6 10.2 43.1 5.0 19.0 80.2 36.4 7.7 55.7 10.4 30.6 69.7 TSPAN8 "CO-029, TM4SF3" ENSG00000127324 "Tetraspanin 8" P19075 12 71125085-71441898 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 951.1;stomach 1: 631.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1688.5;Ductal cells: 943.3;Intestinal goblet cells: 886.7;Paneth cells: 2225.8;Proximal enterocytes: 3546.1;Undifferentiated cells: 1583.9" "Group enriched" "Detected in many" 4 "colorectal cancer: 283.9;pancreatic cancer: 156.9;stomach cancer: 194.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "OE19: 2160.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA022273, CAB026009, HPA044337" Enhanced Approved Vesicles NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB026009: , HPA022273: , HPA044337: AB_2678899" "unprognostic (1.64e-1)" "unprognostic (2.18e-2)" "unprognostic (1.64e-1)" "unprognostic (6.40e-2)" "unprognostic (6.81e-2)" "unprognostic (7.29e-3)" "unprognostic (1.90e-1)" "unprognostic (1.15e-1)" "unprognostic (5.62e-2)" "unprognostic (1.06e-1)" "unprognostic (4.01e-3)" "unprognostic (2.93e-1)" "prognostic unfavorable (9.66e-5)" "unprognostic (1.88e-2)" "unprognostic (1.00e-1)" "unprognostic (2.97e-2)" "prognostic favorable (7.36e-5)" 11.1 9.7 1.9 126.9 5.2 0.0 17.0 6.1 7.1 28.6 1.6 951.1 916.0 12.5 11.7 5.5 13.4 208.2 5.5 1.8 3.4 57.6 53.2 23.0 4.6 12.4 4.9 41.8 60.0 0.4 2.5 2.0 10.5 163.9 862.0 0.3 76.4 10.8 63.7 13.6 848.3 39.2 8.5 0.3 631.0 5.8 4.4 1.1 6.5 12.4 3.8 11.0 4.0 14.6 0.0 0.7 0.0 0.0 5.2 0.8 2.8 0.0 0.0 0.0 0.0 48.8 3.1 0.0 0.2 0.0 0.6 6.5 0.0 0.0 0.0 0.2 0.1 0.0 52.2 3.3 0.0 0.0 0.2 0.4 0.3 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.3 0.0 0.2 3.0 0.3 2160.7 173.3 0.2 0.0 4.9 34.1 41.0 4.1 7.7 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.3 1.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 5.2 6.1 7.1 1.8 3.4 12.4 4.9 10.5 8.5 4.4 14.6 0.8 0.0 2.2 0.0 6.1 20.8 32.5 14.0 0.6 0.3 8.5 1.8 0.3 346.0 76.7 44.1 0.0 1.2 0.0 1688.5 127.2 943.3 34.5 3.7 4.5 3.8 174.1 0.0 0.1 654.9 0.6 37.3 645.3 44.8 4.5 0.0 2.2 26.0 0.2 0.0 0.1 886.7 16.2 2.2 29.1 17.9 44.1 2.6 64.0 0.0 7.8 10.3 0.0 0.5 14.3 325.0 2225.8 32.0 2.2 376.2 3546.1 2.5 30.2 0.6 0.0 7.7 23.6 0.5 1.0 2.7 13.5 1.1 5.8 10.7 1583.9 46.0 TUFT1 ENSG00000143367 "Tuftelin 1" Q9NNX1 1 151540305-151583583 "Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 111.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 69.2;Glandular and luminal cells: 76.8;Suprabasal keratinocytes: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.2" "Group enriched" "Detected in many" 5 "granulocytes: 5.2;T-cells: 3.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 41.7" "HPA028112, HPA054301" Approved Approved Approved Vesicles "Secreted - unknown location" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Vesicles "HPA028112: AB_10603224, HPA054301: AB_2682442" "unprognostic (6.16e-2)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.83e-4)" "unprognostic (4.49e-3)" "unprognostic (1.12e-1)" "unprognostic (2.30e-2)" "unprognostic (1.37e-2)" "unprognostic (8.29e-3)" "unprognostic (9.06e-2)" "unprognostic (6.70e-3)" "unprognostic (7.88e-2)" "unprognostic (2.58e-3)" "unprognostic (1.41e-1)" "unprognostic (1.32e-1)" "unprognostic (1.82e-3)" "unprognostic (4.53e-2)" 5.6 6.8 4.7 2.8 4.2 6.7 10.1 5.0 5.3 25.4 3.4 11.6 7.5 5.3 6.3 48.1 5.1 5.9 4.9 3.8 5.9 14.1 7.0 8.4 0.9 4.0 4.0 7.4 17.2 11.4 7.2 13.3 5.2 9.6 13.0 2.1 18.3 9.2 2.5 111.5 10.8 6.2 3.3 1.5 12.8 5.4 6.2 2.2 5.7 2.7 6.2 12.4 26.8 3.5 40.7 13.7 10.0 11.5 2.3 1.9 63.1 10.7 9.5 41.3 39.6 43.6 31.5 3.5 64.6 12.5 19.5 46.4 17.6 16.2 30.1 27.0 8.7 2.2 23.0 6.7 32.2 0.8 4.7 6.5 18.9 32.5 71.6 24.5 3.4 5.0 3.6 26.8 12.8 16.8 2.0 0.5 11.7 29.6 11.4 0.1 28.1 14.2 34.7 61.8 19.5 8.0 68.2 45.8 8.0 29.4 36.5 2.1 8.6 7.4 51.7 46.2 71.7 6.6 13.7 0.5 6.3 0.9 4.7 5.2 0.6 0.7 0.3 0.1 0.7 0.6 1.0 0.5 0.9 0.2 0.8 0.3 2.5 0.1 0.3 0.1 3.5 0.5 4.7 4.2 5.0 5.3 3.8 5.9 4.0 4.0 5.2 3.3 6.2 3.5 2.1 25.6 2.0 1.6 3.8 69.2 35.2 14.7 35.9 2.5 28.8 20.2 9.8 8.6 19.0 14.7 0.0 28.1 6.6 59.5 13.7 18.2 2.7 43.2 8.9 2.7 32.2 2.7 4.4 15.2 13.9 7.0 46.9 76.8 4.5 9.0 1.1 10.5 4.0 0.0 9.3 39.1 20.3 0.0 12.7 3.2 2.5 6.5 8.8 1.0 2.0 2.1 0.0 8.5 1.8 47.4 34.6 5.3 7.7 21.7 15.4 11.2 15.9 0.5 6.6 4.1 5.5 0.6 3.5 39.6 66.5 56.8 5.8 10.9 35.7 35.6 TVP23A "FAM18A, YDR084C" ENSG00000166676 "Trans-golgi network vesicle protein 23 homolog A" A6NH52 16 10760919-10818794 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.7" "Group enriched" "Detected in many" 6 "Excitatory neurons: 29.0;Granulosa cells: 92.1;Inhibitory neurons: 28.4;Langerhans cells: 47.6;monocytes: 29.1;Oligodendrocyte precursor cells: 23.6" "Cancer enhanced" "Detected in some" "glioma: 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 1.1;NTERA-2: 1.3;SH-SY5Y: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060582 Uncertain Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA060582: AB_2684326" "unprognostic (6.70e-4)" "unprognostic (1.64e-3)" "unprognostic (2.38e-2)" "unprognostic (8.24e-3)" "unprognostic (2.72e-2)" "unprognostic (4.39e-5)" "unprognostic (4.96e-2)" "unprognostic (4.68e-2)" "unprognostic (4.42e-2)" "unprognostic (9.22e-2)" "unprognostic (1.73e-2)" "unprognostic (2.42e-1)" "unprognostic (8.78e-7)" "unprognostic (1.20e-3)" "unprognostic (1.14e-1)" "unprognostic (1.87e-2)" "unprognostic (2.87e-4)" 1.0 1.2 4.5 1.1 4.8 1.8 0.6 3.0 5.7 1.6 1.0 0.8 0.8 0.9 0.5 0.6 1.5 0.9 1.4 4.4 4.4 1.0 1.1 0.9 2.0 3.3 3.8 3.6 1.0 0.0 2.2 0.1 3.8 2.0 0.2 2.2 0.7 0.9 0.5 0.7 1.3 0.6 2.8 1.7 0.8 1.0 4.3 0.8 0.9 0.0 0.6 0.7 0.8 3.6 0.1 0.4 0.3 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.2 0.3 0.0 0.0 0.0 1.1 0.2 0.1 0.6 0.3 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.4 0.0 0.2 0.2 0.3 1.3 0.1 0.0 0.6 0.1 0.2 0.0 0.4 0.2 2.1 0.1 0.2 0.0 0.2 0.2 0.1 0.2 0.3 0.2 0.3 0.1 1.0 0.1 0.3 0.3 0.3 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.6 0.3 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.1 4.5 4.8 3.0 5.7 4.4 4.4 3.3 3.8 3.8 2.8 4.3 3.6 0.2 0.0 1.8 5.2 0.8 1.1 0.0 0.1 0.6 6.4 0.1 0.4 0.6 0.0 0.1 0.0 2.1 0.3 0.1 0.0 0.0 0.0 0.7 0.6 0.4 0.4 0.0 0.0 29.0 0.6 0.6 3.3 0.0 0.3 0.0 92.1 0.0 0.2 0.8 1.7 28.4 0.0 0.0 1.0 47.6 0.3 2.8 4.5 1.8 1.9 29.1 4.7 0.0 23.6 1.1 0.3 0.0 1.5 0.2 0.0 0.0 1.3 0.2 1.3 0.0 0.2 3.6 2.2 3.1 0.1 1.0 1.4 0.5 0.1 0.1 0.1 TXK "BTKL, PSCTK5, PTK4, RLK, TKL" ENSG00000074966 "TXK tyrosine kinase" P42681 4 48066393-48134250 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 12.4;lymphoid tissue: 15.8" "Cell type enhanced" "Detected in many" "dendritic cells: 84.1;NK-cells: 288.4;T-cells: 52.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "NK-cell: 152.3" "Group enriched" "Detected in many" 19 "NK-cells: 152.3;T-cells: 54.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 6.1;HMC-1: 14.0;U-266/70: 6.8;U-266/84: 9.2;WM-115: 32.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA062482 Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA062482: AB_2684778" "unprognostic (1.04e-2)" "unprognostic (2.21e-2)" "unprognostic (4.13e-2)" "unprognostic (9.24e-3)" "unprognostic (1.09e-2)" "unprognostic (2.58e-4)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (1.50e-1)" "unprognostic (6.39e-3)" "unprognostic (8.13e-2)" "unprognostic (4.06e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (1.61e-1)" "unprognostic (2.59e-1)" "unprognostic (2.04e-2)" 0.9 1.0 0.1 7.8 0.0 5.6 0.9 0.0 0.4 0.8 0.3 1.5 1.8 1.0 12.4 1.5 2.0 2.2 0.6 0.0 0.5 1.1 2.1 2.8 15.8 1.2 0.2 0.2 0.8 0.4 0.7 1.9 1.5 0.5 1.4 2.0 1.4 0.5 0.6 2.2 5.6 0.4 0.2 10.6 1.1 1.1 0.8 5.7 1.2 0.0 10.8 2.2 0.9 0.2 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.5 0.1 6.1 0.0 1.8 0.0 0.2 0.3 0.0 0.1 0.6 0.3 0.1 3.1 0.0 0.0 0.0 0.4 14.0 0.0 0.0 0.1 0.0 0.9 0.2 0.6 0.2 0.1 0.8 0.0 0.0 2.8 0.0 0.8 1.0 0.4 0.0 0.0 1.7 1.6 0.0 0.3 0.0 0.0 1.6 0.1 0.0 0.2 0.5 0.0 0.0 0.4 0.1 6.8 9.2 0.6 0.0 0.5 32.0 5.4 0.1 1.0 42.0 0.2 54.8 0.2 21.1 20.2 0.2 0.1 53.2 37.0 2.4 152.3 0.3 0.6 17.6 36.3 0.1 0.0 0.0 0.4 0.0 0.5 1.2 0.2 1.5 0.2 0.8 0.2 0.7 0.0 1.8 0.3 3.2 0.4 0.6 0.0 0.6 0.5 0.8 0.4 1.1 1.5 0.0 0.0 4.2 0.4 84.1 0.2 1.9 1.5 10.1 2.0 0.4 0.9 0.0 10.7 21.5 0.0 0.1 0.6 0.0 5.5 1.3 0.1 3.6 1.5 1.6 0.0 3.3 0.2 0.0 6.9 0.4 2.8 0.3 1.9 1.8 3.7 1.6 1.4 288.4 0.5 0.5 0.1 0.1 0.0 8.9 0.6 0.4 0.5 0.0 0.4 0.0 1.2 0.1 1.0 0.8 0.8 1.1 0.5 52.3 0.1 0.4 0.8 TYR "OCA1, OCA1A, OCAIA" ENSG00000077498 Tyrosinase P14679 11 89177875-89295759 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase, Tumor antigen" "Albinism, Deafness, Disease variant, FDA approved drug targets, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 37 "skin 1: 31.6" "Cell type enriched" "Detected in some" 5 "Melanocytes: 184.9" "Cancer enriched" "Detected in single" 1755 "melanoma: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 995 "SK-MEL-30: 426.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000079, HPA043241, HPA050889, HPA064583" Enhanced Enhanced Vesicles NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "CAB000079: AB_564045, HPA043241: AB_2678383, HPA050889: AB_2681264, HPA064583: " "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (1.85e-3)" "unprognostic (9.75e-3)" 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 31.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 426.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.9 0.3 0.0 0.1 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.5 5.2 0.3 0.0 184.9 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 2.0 0.0 0.1 0.0 0.0 0.0 TYRP1 "b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP" ENSG00000107165 "Tyrosinase related protein 1" P17643 9 12685439-12710285 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 44.8;heart muscle: 59.9;skin 1: 145.0" "Cell type enriched" "Detected in some" 17 "Melanocytes: 2486.6" "Cancer enriched" "Detected in some" 262 "melanoma: 313.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 55 "SK-MEL-30: 1395.0" "Group enriched" "Detected in some" 5 "olfactory bulb: 4.6;thalamus: 1.8" "Low region specificity" "Detected in all" "HPA000937, CAB002520" Enhanced Approved Vesicles NA NA 51000 "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB002520: AB_564153, HPA000937: AB_1080437" "unprognostic (7.48e-2)" "unprognostic (1.10e-3)" "unprognostic (2.28e-1)" "unprognostic (3.16e-3)" "unprognostic (8.10e-2)" "unprognostic (3.82e-3)" "unprognostic (1.53e-1)" "unprognostic (2.25e-3)" "unprognostic (4.46e-1)" "unprognostic (8.71e-2)" "unprognostic (6.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.68e-6)" "unprognostic (1.27e-1)" "unprognostic (5.99e-2)" "unprognostic (1.95e-2)" 0.3 0.0 0.1 0.6 0.4 0.2 4.9 0.3 0.9 0.0 44.8 2.2 5.0 0.0 1.2 10.0 0.2 4.5 59.9 2.6 0.0 16.2 0.0 3.7 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 5.3 2.7 1.3 0.0 4.8 145.0 4.7 1.8 0.1 0.0 2.1 1.1 0.3 0.0 0.0 7.5 0.0 1.1 0.4 1.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 25.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.0 4.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.0 1395.0 0.1 19.5 1.5 0.0 0.0 0.7 0.0 0.9 0.0 0.7 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.9 2.6 0.0 1.2 1.1 2.1 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 92.3 0.1 0.0 0.0 11.7 0.0 0.0 44.3 0.0 0.0 3.7 2.1 0.0 0.0 0.0 144.8 0.3 2.5 0.0 0.0 1.3 0.0 0.0 0.9 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 17.5 4.7 0.3 0.0 2486.6 0.0 0.0 15.9 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 1.6 0.0 0.0 1.4 0.7 0.7 0.0 16.8 0.0 0.5 0.0 0.0 0.2 UBIAD1 "SCCD, TERE1" ENSG00000120942 "UbiA prenyltransferase domain containing 1" Q9Y5Z9 1 11273198-11296049 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Menaquinone biosynthesis, Ubiquinone biosynthesis" "Prenyltransferase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044862 Approved Vesicles NA NA "Cluster 30: Non-specific - Translation" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA044862: AB_2679117" "unprognostic (1.79e-2)" "unprognostic (2.26e-1)" "unprognostic (5.06e-2)" "unprognostic (1.74e-1)" "unprognostic (7.95e-3)" "unprognostic (7.55e-2)" "unprognostic (1.16e-2)" "unprognostic (2.01e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "prognostic favorable (6.80e-5)" "unprognostic (3.00e-1)" "unprognostic (3.89e-1)" "unprognostic (2.03e-2)" "unprognostic (1.25e-1)" 7.3 7.5 5.5 7.6 7.5 7.6 8.3 6.9 7.0 6.8 2.3 7.0 5.5 8.4 6.1 5.9 9.6 4.6 8.2 5.2 6.1 6.5 10.1 6.1 10.2 7.5 7.5 11.5 10.8 10.0 5.8 6.4 6.8 7.1 6.8 8.0 7.0 6.6 17.7 8.1 6.4 7.9 6.6 7.1 7.2 9.2 7.1 11.9 7.7 13.8 10.5 8.1 5.6 10.1 14.5 14.1 11.0 21.3 8.0 7.4 14.8 15.6 12.7 16.4 14.9 16.4 13.1 28.5 15.6 11.1 15.4 19.5 28.1 18.7 19.9 20.0 24.1 19.1 14.5 22.0 14.5 29.5 15.9 11.2 24.9 22.2 26.3 8.7 12.2 25.8 23.1 22.9 11.2 14.8 19.1 14.7 13.3 27.1 20.7 18.0 24.6 34.6 12.7 9.5 13.6 14.5 16.6 16.3 21.5 4.5 12.1 15.3 10.2 14.4 15.5 15.1 20.5 18.6 27.9 52.4 9.2 38.3 18.3 11.5 12.8 19.5 24.3 17.5 27.3 45.3 32.5 24.8 16.9 42.1 48.5 33.3 3.9 20.5 15.6 21.1 33.8 22.2 5.5 7.5 6.9 7.0 5.2 6.1 7.5 7.5 6.8 6.6 7.1 10.1 9.4 9.6 14.6 4.2 19.6 15.4 16.7 11.2 22.2 11.9 13.3 13.7 8.3 11.5 18.1 5.5 8.4 10.6 17.5 7.4 11.7 10.8 34.1 6.3 9.6 9.5 4.9 13.3 4.2 13.3 14.7 11.4 13.3 9.6 7.0 11.3 7.9 19.7 8.7 13.5 6.5 11.1 14.2 8.2 14.1 23.1 12.5 9.5 5.4 4.7 7.1 9.5 14.4 9.0 11.1 11.0 5.3 10.9 14.2 15.0 5.8 8.6 8.9 15.8 0.0 20.2 10.4 24.7 15.7 15.7 12.6 18.9 14.4 12.0 14.1 10.3 UCN2 "SRP, UCN-II, UCNI, URP" ENSG00000145040 "Urocortin 2" Q96RP3 3 48561718-48563781 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 13.1;vagina: 4.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.9;Basal respiratory cells: 1.4" "Cancer enriched" "Detected in many" 5 "melanoma: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 18.8;hTCEpi: 27.3;hTEC/SVTERT24-B: 21.5;SiHa: 19.1;U-251 MG: 20.7;WM-115: 55.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA066841 Uncertain Approved Vesicles "Secreted to blood" NA NA 98600 "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA066841: AB_2685735" "unprognostic (7.98e-2)" "unprognostic (1.35e-1)" "unprognostic (4.80e-2)" "unprognostic (1.96e-2)" "unprognostic (2.39e-2)" "unprognostic (4.26e-2)" "unprognostic (1.92e-3)" "unprognostic (2.02e-3)" "unprognostic (1.62e-1)" "unprognostic (2.93e-3)" "unprognostic (2.52e-3)" "unprognostic (1.09e-1)" "unprognostic (3.34e-14)" "unprognostic (4.39e-2)" "unprognostic (2.75e-1)" "unprognostic (1.36e-1)" "unprognostic (2.88e-2)" 0.1 0.0 0.2 0.3 0.1 0.1 0.4 0.3 0.4 2.3 0.1 0.2 0.1 1.2 0.7 3.4 0.2 0.4 0.3 0.2 0.4 1.4 0.0 0.2 0.0 0.3 0.3 0.2 0.0 0.0 0.3 0.2 0.3 3.1 0.0 0.0 1.6 0.4 0.3 13.1 0.2 0.2 0.2 0.7 0.2 1.4 0.3 0.0 0.0 0.0 0.1 0.5 4.5 0.2 0.0 3.1 0.5 0.1 1.8 1.1 2.6 9.7 12.1 5.9 4.4 0.0 0.0 0.0 0.4 2.3 7.0 1.9 0.0 11.6 3.2 9.2 0.2 0.2 18.8 1.5 2.0 0.0 0.5 1.3 27.3 21.5 4.3 4.1 0.0 0.2 0.0 0.2 0.9 0.0 0.0 1.8 0.8 0.0 0.2 0.2 0.3 0.0 1.8 0.0 0.0 0.0 19.1 0.0 14.5 1.7 0.3 0.4 0.0 2.6 1.8 0.3 20.7 0.1 0.3 0.0 8.8 0.1 55.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.4 0.2 0.4 0.3 0.3 0.3 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 2.9 0.3 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 USP6 "HRP1, Tre-2, TRE17, Tre2, TRESMCR" ENSG00000129204 "Ubiquitin specific peptidase 6" P35125 17 5116032-5175034 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Calmodulin-binding, Hydrolase, Protease, Thiol protease" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "skeletal muscle: 19.6;testis: 13.4" "Cell type enhanced" "Detected in many" "Early spermatids: 24.4;Spermatocytes: 26.9" "Cancer enriched" "Detected in single" 14 "testis cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046969 Uncertain Vesicles NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 37: Myocytes - Muscle contraction" Vesicles "HPA046969: " "unprognostic (3.89e-2)" "unprognostic (3.79e-3)" "unprognostic (2.50e-1)" "unprognostic (1.85e-1)" "unprognostic (9.32e-2)" "unprognostic (3.50e-3)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (3.45e-2)" "unprognostic (2.46e-2)" "unprognostic (7.91e-4)" "unprognostic (6.28e-3)" "unprognostic (3.24e-4)" "unprognostic (3.75e-2)" "unprognostic (3.13e-1)" "unprognostic (2.71e-1)" "unprognostic (7.09e-4)" 0.4 0.3 0.2 0.2 0.5 0.1 0.7 0.3 0.6 1.4 1.5 0.8 0.0 0.9 0.7 0.2 0.5 0.5 0.4 0.4 0.3 0.6 0.1 0.4 0.3 0.7 0.2 2.6 0.3 0.0 0.6 0.5 0.6 0.6 0.3 2.5 0.5 0.4 19.6 0.6 0.3 0.9 0.2 0.4 0.2 13.4 0.5 0.0 0.9 0.6 0.2 0.3 0.5 0.9 0.1 0.1 0.3 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.2 0.4 0.3 0.1 0.1 0.0 0.3 0.2 0.0 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 0.3 0.6 0.4 0.3 0.7 0.2 0.6 0.2 0.5 0.9 2.0 6.4 10.8 0.0 0.4 10.8 1.0 1.1 0.0 8.5 4.0 3.8 1.6 5.7 3.5 3.7 12.5 0.6 1.0 0.1 3.9 0.0 24.4 1.1 2.1 3.0 0.0 5.3 1.2 0.0 0.8 1.8 0.0 1.4 0.0 1.2 3.6 3.2 2.7 1.7 1.0 0.0 0.0 5.4 6.4 13.5 1.8 3.1 3.6 2.8 3.2 5.1 0.0 0.0 2.9 0.1 0.1 2.6 0.1 2.1 0.0 3.2 4.0 12.3 6.6 5.9 1.7 26.9 11.5 0.0 10.4 0.7 1.1 0.9 0.2 1.1 USP9X "DFFRX, FAF, MRX99" ENSG00000124486 "Ubiquitin specific peptidase 9 X-linked" Q93008 X 41085445-41236579 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, Chromosome partition, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011618, HPA047417, CAB070164" Approved Uncertain Vesicles NA NA 24000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Vesicles "CAB011618: AB_470860, CAB070164: AB_10011071, HPA047417: " "unprognostic (5.42e-3)" "unprognostic (6.42e-2)" "unprognostic (3.19e-3)" "unprognostic (2.94e-2)" "unprognostic (5.99e-2)" "unprognostic (4.76e-1)" "unprognostic (1.82e-2)" "unprognostic (4.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.72e-1)" "unprognostic (7.07e-2)" "unprognostic (1.09e-1)" "unprognostic (5.82e-2)" "unprognostic (1.59e-1)" "unprognostic (4.19e-2)" "unprognostic (2.78e-1)" "unprognostic (1.33e-1)" 16.4 16.8 11.9 14.3 13.9 18.2 14.2 12.7 12.8 15.3 14.3 14.8 13.6 15.4 14.9 14.1 16.0 13.0 15.3 14.3 13.2 17.8 33.9 14.4 15.8 12.2 13.1 13.4 16.0 30.0 10.2 18.4 13.8 12.3 13.7 22.0 11.5 15.3 39.1 13.8 14.3 16.3 12.5 13.3 13.8 17.5 12.8 18.8 19.5 28.4 16.2 15.0 12.6 16.4 38.6 44.2 39.1 40.2 33.0 32.7 8.8 21.5 28.8 23.8 27.5 21.1 16.9 25.7 11.5 48.5 71.3 25.3 67.1 39.7 39.7 32.0 50.5 29.3 41.3 19.9 27.6 26.4 21.0 29.3 17.9 56.4 53.4 35.5 37.2 17.1 36.0 20.3 38.6 29.1 18.8 12.7 42.6 14.1 24.7 20.3 51.8 16.9 24.7 30.7 22.2 20.8 89.0 26.7 26.0 69.8 24.3 16.2 40.2 36.6 27.6 34.6 24.0 19.1 22.3 30.9 26.4 12.1 18.5 1.7 2.3 3.0 2.5 1.9 3.6 2.8 3.0 2.7 2.6 2.1 3.0 2.8 6.4 2.5 2.5 2.1 2.8 1.5 11.9 13.9 12.7 12.8 14.3 13.2 12.2 13.1 13.8 12.5 12.8 16.4 38.1 41.7 35.1 48.0 42.6 48.3 30.8 29.6 55.2 38.1 41.3 29.5 83.5 54.3 37.9 27.6 37.5 39.6 46.3 58.5 7.9 28.4 14.9 85.5 56.9 43.6 26.9 41.0 84.9 26.5 25.4 41.4 41.8 136.9 25.9 58.3 45.7 62.8 32.6 37.0 86.0 39.1 18.3 47.8 42.1 15.4 33.2 55.5 33.8 67.5 44.6 31.3 30.9 74.9 108.0 32.6 40.1 49.2 38.8 35.6 47.7 21.5 35.8 31.2 32.9 70.6 48.3 86.4 82.9 55.2 55.3 46.7 42.4 45.8 38.0 40.2 USP9Y "AZFA, DFFRY" ENSG00000114374 "Ubiquitin specific peptidase 9 Y-linked" O00507 Y 12537650-12860839 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Excitatory neurons: 89.5;Inhibitory neurons: 69.5" "Cancer enhanced" "Detected in many" "prostate cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 21.5;RT4: 17.4" "Not detected" "Not detected" HPA057687 Uncertain Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA057687: " "unprognostic (2.63e-1)" "unprognostic (8.97e-2)" "unprognostic (1.10e-5)" "unprognostic (8.46e-3)" "unprognostic (4.93e-2)" "unprognostic (2.53e-2)" "unprognostic (2.77e-1)" "unprognostic (3.17e-2)" "unprognostic (1.71e-1)" "unprognostic (4.05e-2)" "unprognostic (1.41e-4)" "unprognostic (2.28e-1)" "unprognostic (1.19e-2)" "unprognostic (1.42e-1)" 3.6 5.2 1.3 1.7 1.4 2.6 3.3 2.8 5.2 0.0 2.5 4.5 1.7 0.0 7.2 5.2 0.0 4.6 5.5 1.3 1.4 7.1 3.0 5.2 2.2 1.2 1.1 0.0 6.0 3.5 8.8 2.3 1.3 9.7 4.9 12.9 4.9 7.0 5.2 3.2 4.4 0.0 1.0 5.1 3.9 4.2 1.4 0.0 5.7 9.7 5.6 4.5 0.0 2.4 0.0 4.7 0.0 0.0 0.0 0.0 5.3 14.2 14.6 7.2 8.5 0.0 0.0 7.7 0.0 12.2 0.0 0.0 0.0 0.0 8.6 8.1 0.0 7.3 0.0 9.5 5.8 0.0 0.0 9.7 8.9 0.0 0.0 0.0 0.0 3.0 0.0 0.0 12.2 0.0 9.8 0.0 4.6 0.0 0.0 0.0 3.5 2.1 21.5 17.4 7.2 0.0 0.0 0.0 4.4 12.5 0.0 0.2 10.6 9.5 0.0 0.0 7.0 0.0 9.7 15.1 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.9 0.4 0.7 0.5 0.1 0.7 0.8 0.5 0.0 0.1 0.0 0.6 0.6 0.0 1.3 1.4 2.8 5.2 1.3 1.4 1.2 1.1 1.3 1.0 1.4 2.4 0.0 25.6 23.5 29.4 11.0 11.7 8.5 9.5 18.2 23.6 0.0 0.0 26.5 7.2 12.6 20.2 64.6 6.3 5.3 0.3 1.9 6.9 0.5 0.0 0.0 5.8 0.0 5.9 89.5 0.0 1.7 8.1 6.6 0.0 2.5 0.0 6.1 2.3 3.1 26.9 69.5 1.1 8.2 5.6 9.3 1.1 12.5 3.6 3.6 31.9 3.6 8.8 14.4 28.6 17.4 2.3 0.0 15.4 4.1 13.2 0.7 6.3 19.9 23.1 0.0 5.2 4.4 2.8 2.6 20.6 11.6 3.4 14.7 0.0 1.5 11.9 VAMP7 "SYBL1, TI-VAMP, VAMP-7" ENSG00000124333 "Vesicle associated membrane protein 7" P51809 X 155881345-155943769 "Predicted intracellular proteins, Predicted membrane proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036733 Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA036733: AB_10672228" "unprognostic (7.54e-3)" "unprognostic (1.35e-2)" "unprognostic (2.07e-1)" "unprognostic (1.04e-1)" "unprognostic (6.15e-3)" "unprognostic (2.70e-2)" "unprognostic (5.77e-2)" "unprognostic (7.95e-2)" "unprognostic (7.18e-2)" "unprognostic (3.38e-3)" "unprognostic (1.02e-1)" "unprognostic (1.15e-1)" "prognostic favorable (2.83e-4)" "unprognostic (1.29e-1)" "unprognostic (3.42e-1)" "unprognostic (2.47e-1)" "unprognostic (2.97e-1)" 29.4 24.3 17.8 24.1 20.6 37.1 23.8 22.3 24.9 23.2 18.3 22.9 23.4 21.4 15.5 22.6 16.5 22.2 19.6 18.1 21.4 39.2 47.9 24.8 26.4 20.7 20.5 17.9 14.3 32.3 8.7 40.5 21.5 21.4 24.4 10.3 17.3 20.1 21.9 20.1 27.5 28.2 20.4 21.8 18.4 14.9 19.9 29.9 24.4 24.1 28.6 25.6 15.9 23.0 72.9 31.3 21.0 43.6 57.0 54.3 56.3 55.3 49.1 49.0 98.4 33.8 46.5 100.6 100.0 66.9 55.5 25.5 47.6 38.9 64.5 42.3 41.6 41.8 43.1 24.3 63.6 86.9 62.8 50.9 37.9 54.8 49.8 42.8 55.4 43.5 91.1 54.2 56.0 36.5 34.1 48.8 15.0 54.1 45.3 25.5 41.2 75.3 65.6 36.2 16.0 46.0 32.7 32.6 49.6 54.8 31.9 71.8 58.4 44.8 46.7 65.0 79.6 123.8 167.8 138.9 39.2 104.4 51.0 86.8 25.3 39.6 15.1 27.0 19.1 12.3 17.7 18.6 26.4 13.2 16.2 17.5 21.9 22.7 26.7 15.0 22.0 22.4 17.8 20.6 22.3 24.9 18.1 21.4 20.7 20.5 21.5 20.4 19.9 23.0 17.8 3.2 9.2 11.1 21.2 19.6 14.7 11.8 20.5 7.6 16.6 9.5 12.3 5.7 12.5 7.3 6.2 48.4 24.9 14.1 41.1 28.0 6.9 13.8 14.5 19.8 13.2 31.4 14.2 26.0 49.7 19.6 12.2 13.7 31.1 22.5 20.3 25.1 31.1 6.7 14.6 12.8 10.2 30.8 49.0 6.9 17.7 35.9 19.6 7.5 32.5 10.4 29.9 8.0 19.2 29.9 13.5 19.5 15.2 17.5 25.3 52.9 10.5 4.6 26.3 10.8 18.9 45.4 26.3 20.3 19.5 69.8 21.6 25.3 15.3 20.1 VAV2 ENSG00000160293 "Vav guanine nucleotide exchange factor 2" P52735 9 133761894-133992604 "Plasma proteins, Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 48.3;Inhibitory neurons: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.3" "Group enriched" "Detected in many" 22 "B-cells: 3.3;dendritic cells: 1.1;monocytes: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003224 Uncertain Approved Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA003224: AB_1080554" "unprognostic (1.56e-1)" "unprognostic (1.10e-1)" "unprognostic (1.07e-2)" "unprognostic (1.09e-1)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (6.57e-2)" "unprognostic (1.16e-3)" "unprognostic (1.83e-2)" "unprognostic (3.74e-3)" "unprognostic (4.73e-2)" "unprognostic (9.16e-2)" "prognostic favorable (7.39e-7)" "unprognostic (8.64e-3)" "unprognostic (3.00e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (3.97e-2)" 8.4 26.8 9.3 10.7 8.8 3.0 7.7 7.4 9.8 12.0 10.9 11.8 20.9 9.9 7.2 6.7 12.2 10.8 7.4 11.6 9.9 21.3 46.1 16.8 13.3 11.6 16.0 5.5 38.6 10.8 8.0 13.1 13.2 10.2 9.6 3.0 13.2 8.9 2.0 6.1 22.4 6.9 8.9 13.9 9.5 4.4 9.9 6.2 13.8 2.3 13.3 11.4 7.9 8.4 12.5 21.6 33.3 13.5 9.0 15.1 85.8 24.6 13.5 20.3 12.2 33.0 19.0 3.6 19.6 24.6 26.2 72.8 31.6 53.0 10.4 21.3 7.3 4.2 28.3 37.2 33.4 10.3 1.6 15.0 33.5 17.9 25.3 13.6 22.9 7.3 7.3 6.0 14.2 63.5 0.8 5.1 16.3 54.3 20.5 33.9 28.2 12.1 46.1 22.4 36.9 24.9 64.7 42.7 8.8 21.3 26.0 14.5 18.7 28.6 16.0 28.7 34.5 0.4 0.3 6.8 19.1 8.8 18.0 0.0 0.8 0.0 0.0 2.0 0.0 3.3 0.0 0.0 1.1 2.1 0.0 0.0 0.0 0.0 1.4 0.7 0.0 0.5 9.3 8.8 7.4 9.8 11.6 9.9 11.6 16.0 13.2 8.9 9.9 8.4 4.8 0.0 5.4 20.5 11.2 5.1 3.0 10.1 4.0 1.9 6.7 5.6 4.7 21.5 7.5 36.8 0.0 1.3 0.6 27.0 3.9 9.2 2.5 6.9 6.4 6.6 28.2 0.4 8.5 12.5 18.3 5.0 9.7 13.9 0.0 24.6 6.8 48.3 6.2 0.0 40.9 9.8 6.1 5.4 7.2 7.9 7.2 7.7 1.8 8.4 9.3 4.2 2.1 31.2 2.6 24.7 15.6 6.0 3.3 6.3 35.7 13.6 3.3 1.8 13.1 6.4 8.8 0.1 3.8 2.1 2.7 1.0 1.7 12.0 13.5 2.1 VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 975.7;Granulosa cells: 1131.8;Kupffer cells: 547.3;Macrophages: 605.6;monocytes: 948.1;Oligodendrocyte precursor cells: 1644.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 88.9" "Group enriched" "Detected in many" 20 "dendritic cells: 88.9;monocytes: 240.0" "Cell line enhanced" "Detected in many" "AF22: 300.5;HSkMC: 199.5;hTERT-RPE1: 959.0;RPTEC TERT1: 381.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004726, CAB008979" Supported Approved Vesicles "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB008979: , HPA004726: AB_1080561" "unprognostic (7.90e-2)" "unprognostic (9.03e-3)" "unprognostic (7.09e-2)" "unprognostic (6.06e-3)" "unprognostic (1.87e-1)" "unprognostic (4.49e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (4.36e-3)" "unprognostic (2.68e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.17e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.15e-1)" "unprognostic (4.44e-2)" "unprognostic (5.30e-3)" 42.0 23.9 18.6 74.9 20.8 32.6 15.6 24.2 23.0 29.4 5.2 11.3 3.8 17.8 1.8 3.8 8.6 30.5 45.0 25.7 27.8 6.5 2.7 34.4 2.3 36.1 19.3 2.1 3.1 2.4 2.1 73.5 31.3 6.8 10.7 0.2 7.6 4.2 3.9 11.2 5.7 48.0 28.9 13.9 7.7 4.8 44.9 2.7 6.6 6.8 1.9 48.3 7.2 42.7 0.2 5.6 300.5 0.1 119.8 81.5 0.1 2.3 6.2 2.1 1.5 3.1 0.2 0.0 45.2 111.5 3.9 0.0 0.4 0.4 1.7 0.1 9.8 2.1 0.0 2.3 5.5 0.1 0.0 199.5 0.1 127.6 1.2 959.0 0.1 0.0 0.0 0.1 64.6 0.0 0.5 0.0 51.1 0.0 10.3 0.0 63.0 0.1 381.0 0.0 3.6 15.5 0.0 0.0 0.2 33.2 0.2 0.5 116.5 90.6 0.5 168.3 179.0 0.0 0.1 0.2 41.8 0.1 16.4 8.3 240.0 0.5 0.5 31.3 0.3 0.2 0.1 0.1 88.9 0.1 0.1 0.0 3.9 0.5 3.5 1.7 0.0 94.0 18.6 20.8 24.2 23.0 25.7 27.8 36.1 19.3 31.3 28.9 44.9 42.7 23.4 19.2 19.8 128.9 5.5 38.6 10.6 14.9 1.2 0.0 1.8 1.9 8.2 44.3 17.5 25.8 0.0 5.9 7.4 0.0 0.0 1.9 3.0 64.4 975.7 29.9 0.0 5.2 1.5 0.7 7.0 348.1 3.6 241.3 12.6 1131.8 16.8 3.6 25.6 0.0 30.7 0.2 0.0 547.3 83.1 2.5 18.6 605.6 44.4 20.6 948.1 0.0 13.4 1644.7 1.5 32.3 1.1 117.8 2.5 2.5 0.0 1.8 16.2 0.0 0.0 11.0 80.6 0.9 1.2 1.1 28.7 11.5 12.7 1.6 0.3 0.9 VNN1 Tiff66 ENSG00000112299 "Vanin 1" O95497 6 132680849-132714055 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "gallbladder: 89.2;intestine: 136.3;liver: 218.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 50.1;Ductal cells: 244.2;Hepatocytes: 70.6;Pancreatic endocrine cells: 98.0;Proximal enterocytes: 61.7" "Cancer enhanced" "Detected in many" "liver cancer: 41.5" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "classical monocyte: 13.7;non-classical monocyte: 11.9" "Group enriched" "Detected in many" 80 "dendritic cells: 5.0;granulocytes: 8.5;monocytes: 13.7" "Cell line enhanced" "Detected in some" "A-431: 2.5;CAPAN-2: 2.5;EFO-21: 8.7;HBEC3-KT: 2.3;LHCN-M2: 2.5" "Region enhanced" "Detected in single" "white matter: 2.4" "Not detected" "Not detected" "HPA046103, HPA064145" Approved Approved Vesicles "Intracellular and membrane" NA NA 980000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA046103: , HPA064145: AB_2685197" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (9.95e-2)" "unprognostic (1.35e-3)" "unprognostic (6.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.20e-1)" "unprognostic (4.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.64e-2)" "unprognostic (2.11e-2)" "unprognostic (4.62e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (2.26e-2)" "unprognostic (4.42e-2)" "unprognostic (2.16e-1)" "unprognostic (2.34e-1)" 2.7 0.6 0.3 3.1 0.6 9.4 1.1 0.5 1.5 1.0 0.0 6.2 136.3 8.9 0.2 0.6 2.6 89.2 0.6 0.2 0.3 21.7 218.7 4.7 2.5 0.6 0.3 0.3 1.4 0.1 0.1 2.7 1.2 0.3 1.8 1.0 2.3 0.2 0.3 0.9 79.5 0.9 0.2 10.1 1.5 0.5 0.5 0.6 0.4 1.1 2.5 1.6 0.7 0.9 2.5 0.0 0.3 0.1 0.0 0.7 0.5 0.2 0.2 0.0 0.0 0.0 2.5 0.1 8.7 0.0 0.4 0.0 0.0 2.3 0.6 0.0 0.0 0.1 0.1 1.4 1.3 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.5 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.1 1.1 0.5 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.6 0.0 0.2 0.1 0.2 0.0 0.1 0.2 0.1 0.3 3.0 13.7 0.0 0.0 8.0 0.0 0.0 0.0 0.0 5.0 0.1 0.0 0.0 8.5 0.0 11.9 0.2 0.0 3.8 0.3 0.6 0.5 1.5 0.2 0.3 0.6 0.3 1.2 0.2 0.5 0.9 0.0 0.0 3.0 0.0 0.3 1.3 0.2 14.9 0.0 0.0 1.2 0.4 0.2 50.1 11.4 1.8 0.0 0.1 0.2 12.5 0.0 244.2 0.0 7.6 4.1 0.2 0.0 0.0 0.0 19.4 0.1 0.3 4.6 39.6 0.0 0.0 1.1 70.6 18.1 0.0 0.0 11.2 22.4 12.0 3.9 0.0 0.0 23.1 0.0 0.0 17.6 0.0 0.0 0.0 0.0 98.0 1.6 0.0 0.5 6.6 61.7 21.9 16.0 0.0 0.0 0.4 1.1 0.1 0.0 0.1 0.1 0.1 0.5 0.0 2.0 14.7 VPS25 "DERP9, EAP20, MGC10540" ENSG00000131475 "Vacuolar protein sorting 25 homolog" Q9BRG1 17 42773449-42779599 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004978, HPA021992, HPA052217, HPA057284" Uncertain Supported Vesicles NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB004978: AB_426095, HPA021992: , HPA052217: AB_2681765, HPA057284: AB_2683397" "unprognostic (3.63e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.18e-4)" "unprognostic (7.37e-2)" "unprognostic (7.57e-2)" "unprognostic (9.83e-3)" "unprognostic (2.76e-3)" "unprognostic (5.84e-2)" "unprognostic (1.25e-1)" "unprognostic (2.90e-1)" "unprognostic (8.10e-3)" "unprognostic (3.88e-1)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.91e-2)" 36.6 40.3 32.8 32.5 33.0 44.3 53.3 34.8 36.8 41.6 36.6 61.9 53.8 35.5 65.3 91.4 58.9 33.4 43.5 32.9 33.2 70.1 68.6 31.8 37.8 32.9 32.8 33.2 49.0 72.3 27.6 46.7 33.5 40.2 68.4 31.2 48.7 36.5 51.3 50.5 45.4 42.8 33.5 37.1 50.0 27.4 33.8 51.3 40.9 41.3 57.2 44.8 44.3 34.0 67.2 136.6 101.8 62.1 126.9 86.5 94.5 83.0 117.1 167.5 116.3 117.9 77.0 66.8 135.8 122.0 88.5 68.7 142.2 181.8 107.9 61.2 178.7 50.6 87.0 177.5 131.0 95.7 64.6 118.2 115.4 148.9 158.0 99.1 106.7 79.0 175.6 65.5 102.1 96.5 138.8 105.2 78.9 152.0 95.3 51.1 123.3 108.7 202.6 75.8 86.3 66.7 46.8 60.1 129.6 155.8 138.4 100.2 58.0 105.7 68.4 60.0 90.3 64.0 39.4 97.9 92.7 64.5 79.6 85.1 76.9 106.7 38.8 89.0 39.9 48.8 42.4 46.4 80.3 46.6 42.3 40.7 44.9 78.9 82.7 54.1 43.1 59.6 32.8 33.0 34.8 36.8 32.9 33.2 32.9 32.8 33.5 33.5 33.8 34.0 26.3 25.6 36.3 4.2 25.3 13.9 41.0 88.3 16.5 24.1 44.4 46.6 26.9 51.5 65.7 62.5 14.6 136.1 22.0 74.3 133.1 135.9 2.6 61.8 48.5 35.4 41.0 47.9 3.5 152.4 186.5 40.8 40.8 55.9 29.2 21.5 29.6 46.4 102.3 23.5 3.5 70.5 85.5 34.5 12.7 5.6 27.7 33.0 42.7 0.0 46.7 56.1 44.3 2.5 4.7 134.4 75.7 30.5 40.9 44.4 83.5 93.6 74.9 29.5 32.9 13.5 69.9 42.8 46.7 61.9 22.9 121.6 22.8 69.9 63.4 53.5 VPS37D "MGC35352, WBSCR24" ENSG00000176428 "VPS37D subunit of ESCRT-I" Q86XT2 7 73667831-73672112 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.0;Collecting duct cells: 11.0;Distal tubular cells: 9.8;Muller glia cells: 13.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040978 Uncertain Approved Vesicles NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA040978: AB_10805833" "unprognostic (2.98e-2)" "unprognostic (2.17e-1)" "unprognostic (1.13e-2)" "unprognostic (7.85e-2)" "unprognostic (1.93e-1)" "unprognostic (3.85e-2)" "unprognostic (2.54e-1)" "unprognostic (3.94e-1)" "unprognostic (8.80e-2)" "unprognostic (1.97e-1)" "prognostic favorable (2.07e-5)" "unprognostic (4.19e-2)" "prognostic favorable (5.80e-9)" "unprognostic (9.63e-2)" "unprognostic (1.67e-1)" "unprognostic (1.25e-2)" "unprognostic (1.43e-1)" 1.8 1.3 8.4 0.3 8.7 0.2 2.4 7.9 12.1 6.1 3.5 3.1 1.8 3.7 2.8 0.8 3.6 1.4 2.3 8.9 7.9 11.3 9.6 1.0 0.2 7.9 7.3 4.2 4.0 2.7 3.3 0.3 8.0 3.7 0.2 1.6 3.2 2.0 1.3 2.5 1.9 0.7 6.3 0.9 2.1 7.1 8.6 0.3 3.4 0.5 0.1 2.2 2.8 7.0 0.5 2.3 1.8 3.8 1.2 2.4 1.1 1.0 1.5 0.8 1.0 0.2 0.7 0.8 0.9 1.3 2.1 0.3 1.9 0.9 0.2 0.3 2.0 0.0 0.2 2.6 3.2 0.0 1.1 1.9 0.5 1.1 0.3 3.5 0.9 3.2 1.1 0.2 1.1 2.8 0.6 0.0 1.2 0.7 3.3 0.1 0.0 0.1 3.0 0.2 3.7 11.8 0.0 1.6 2.3 0.3 3.8 0.1 1.3 2.2 3.0 1.3 0.8 1.4 0.1 1.1 5.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 8.7 7.9 12.1 8.9 7.9 7.9 7.3 8.0 6.3 8.6 7.0 2.4 0.0 0.0 1.3 0.2 1.0 0.8 0.3 0.6 13.0 3.4 3.8 1.8 1.5 0.1 11.0 0.0 0.2 0.1 0.2 9.8 4.0 1.1 3.6 3.1 1.1 4.9 0.0 1.6 0.8 0.4 1.6 0.0 5.1 0.0 5.9 1.8 5.3 0.1 0.0 2.7 0.4 2.0 0.0 0.4 0.9 1.8 0.2 5.4 1.0 0.6 13.9 0.0 1.0 0.9 1.8 1.4 2.6 0.3 1.0 2.0 8.3 0.2 5.3 0.0 0.9 2.7 0.6 8.3 0.1 1.1 0.3 0.2 0.9 0.7 0.4 VSTM1 UNQ3033 ENSG00000189068 "V-set and transmembrane domain containing 1" Q6UX27 19 54040825-54063953 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 43.2" "Cell type enhanced" "Detected in some" "Early spermatids: 3.4;Late spermatids: 20.3;Macrophages: 4.5;monocytes: 12.4;NK-cells: 3.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 16 "eosinophil: 129.2" "Lineage enriched" "Detected in many" 16 "granulocytes: 129.2" "Cell line enhanced" "Detected in some" "HMC-1: 1.0;hTERT-HME1: 1.0;U-2 OS: 1.0" "Low region specificity" "Detected in all" HPA059365 Approved Vesicles "Secreted to blood" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA059365: " "unprognostic (5.13e-2)" "unprognostic (5.31e-2)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (3.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-1)" "unprognostic (9.47e-2)" "unprognostic (1.31e-5)" "unprognostic (3.73e-1)" "unprognostic (1.14e-1)" "unprognostic (9.74e-2)" "unprognostic (4.67e-2)" 0.2 0.1 0.0 0.2 0.0 43.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.1 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.0 0.0 1.4 0.0 4.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.0 3.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 7.4 129.2 0.0 6.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 8.1 0.0 0.0 4.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 3.4 0.2 0.1 0.1 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 2.1 0.0 0.4 0.0 0.0 2.5 0.0 20.3 0.0 4.5 0.0 0.0 12.4 0.0 3.1 0.5 0.6 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 WASH6P "CXYorf1, FAM39A" ENSG00000182484 "WASP family homolog 6, pseudogene" X 156020826-156025710 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 6 "granulocytes: 225.3" "Cancer enhanced" "Detected in all" "urothelial cancer: 10.6" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" HPA002689 Uncertain Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 60: Granulocytes - Receptor signaling" Vesicles "HPA002689: AB_1078803" "unprognostic (2.01e-1)" "unprognostic (3.42e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (7.56e-4)" "unprognostic (4.69e-2)" "unprognostic (4.20e-2)" "unprognostic (1.53e-2)" "unprognostic (2.23e-2)" "unprognostic (1.19e-1)" "unprognostic (8.93e-2)" "unprognostic (1.33e-3)" "unprognostic (3.94e-2)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (2.15e-1)" "unprognostic (1.45e-1)" "unprognostic (5.86e-3)" 1.0 1.3 1.0 1.7 1.0 3.5 1.0 1.2 1.6 0.5 1.3 1.0 2.6 1.6 2.7 0.4 1.1 0.8 1.2 1.2 1.0 2.3 0.7 1.2 1.8 1.8 1.2 1.7 4.1 0.7 1.2 1.5 1.1 0.7 3.6 0.9 1.2 6.5 3.1 2.2 0.6 0.8 2.9 1.7 2.3 1.6 1.1 1.2 0.6 0.9 0.7 2.5 9.6 1.5 1.6 5.0 0.7 0.0 5.9 2.5 0.4 0.8 1.5 0.4 5.2 3.1 1.7 1.4 4.0 7.3 1.2 2.0 0.7 0.7 1.7 4.7 0.6 1.3 0.0 1.8 3.7 0.2 0.9 1.4 2.0 0.5 1.2 0.9 6.2 4.6 0.0 1.2 7.9 4.1 2.3 4.2 0.9 7.0 3.0 2.0 0.3 0.4 4.2 6.3 3.1 4.7 5.7 1.3 6.6 5.8 3.1 3.5 3.4 3.3 3.9 8.0 9.8 1.8 0.8 3.1 3.9 0.4 0.2 0.0 0.3 0.2 0.3 0.4 0.0 0.3 0.2 0.3 0.1 0.2 0.1 0.8 1.1 0.2 0.4 0.3 1.0 1.0 1.2 1.6 1.2 1.0 1.8 1.2 1.5 0.8 1.6 2.5 0.0 35.3 23.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.2 5.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 225.3 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 5.3 0.0 WASHC1 "FAM39E, FLJ00038, WASH1" ENSG00000181404 "WASH complex subunit 1" A8K0Z3 9 14475-73865 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 60.7;Distal tubular cells: 50.9;Proximal tubular cells: 47.5;Syncytiotrophoblasts: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA002689 Uncertain Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA002689: AB_1078803" "unprognostic (9.43e-2)" "unprognostic (1.62e-2)" "unprognostic (3.16e-2)" "unprognostic (1.30e-1)" "unprognostic (1.43e-1)" "unprognostic (2.33e-2)" "unprognostic (3.22e-3)" "unprognostic (2.06e-2)" "unprognostic (5.00e-1)" "unprognostic (5.40e-3)" "unprognostic (3.37e-3)" "unprognostic (6.95e-2)" "unprognostic (3.90e-2)" "unprognostic (1.88e-1)" "unprognostic (3.38e-1)" "unprognostic (2.31e-2)" "unprognostic (1.02e-1)" 15.7 18.1 13.2 7.1 14.2 16.3 17.6 13.2 15.1 24.5 16.5 19.6 10.2 20.3 21.9 19.2 24.1 9.0 17.9 13.3 13.5 25.9 20.9 17.1 13.4 14.4 13.8 23.0 21.9 5.2 21.2 6.6 14.3 27.0 4.7 15.9 17.6 13.5 22.8 26.1 21.9 15.3 13.4 29.0 18.3 24.1 14.5 8.6 22.1 6.8 6.0 19.7 20.5 14.9 13.5 8.5 5.0 10.3 8.5 5.7 12.4 11.7 11.4 6.9 5.5 8.4 8.3 5.7 6.6 4.8 6.2 16.7 7.4 5.7 2.5 5.9 14.4 5.5 7.0 8.6 4.7 11.3 10.0 4.3 4.2 3.5 4.7 17.3 2.1 5.0 12.6 21.0 2.2 4.0 11.6 9.4 9.2 9.1 10.5 7.9 4.3 7.2 5.1 9.8 5.6 14.9 6.8 14.3 8.6 6.2 8.6 10.5 8.0 9.2 6.7 4.0 10.3 9.4 7.9 4.5 8.6 12.0 8.6 1.2 2.5 2.2 1.9 2.7 1.5 1.3 1.5 1.6 2.3 1.2 1.6 1.3 1.4 2.1 4.0 2.1 1.8 1.5 13.2 14.2 13.2 15.1 13.3 13.5 14.4 13.8 14.3 13.4 14.5 14.9 34.5 22.4 22.5 0.0 10.5 0.0 0.0 0.0 0.0 0.0 29.0 28.3 0.0 0.0 7.4 60.7 0.0 37.4 21.5 0.0 50.9 13.7 0.0 24.7 28.6 7.5 0.0 0.0 0.0 15.8 26.1 10.8 0.0 22.9 16.4 27.3 0.0 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 4.6 0.0 0.0 0.0 0.0 13.1 0.0 0.0 6.7 0.0 0.0 47.5 8.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 42.8 11.4 14.3 0.0 0.0 WASHC3 "CCDC53, CGI-116" ENSG00000120860 "WASH complex subunit 3" Q9Y3C0 12 102012840-102062149 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 125.2;Hofbauer cells: 73.1;Proximal tubular cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038339 Uncertain Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA038339: AB_2675966" "unprognostic (4.25e-2)" "unprognostic (1.61e-2)" "unprognostic (2.28e-1)" "unprognostic (3.45e-3)" "unprognostic (1.21e-2)" "unprognostic (2.42e-1)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (1.04e-1)" "unprognostic (9.63e-2)" "unprognostic (7.54e-2)" "unprognostic (4.98e-2)" "unprognostic (7.81e-2)" "unprognostic (7.41e-2)" "unprognostic (1.74e-1)" "unprognostic (1.08e-1)" "unprognostic (1.08e-1)" 27.3 32.2 41.3 14.2 41.9 13.2 24.7 42.8 57.2 26.4 38.3 33.7 13.6 27.5 35.7 28.4 18.0 17.7 35.0 42.8 44.9 41.6 41.1 20.6 22.8 44.6 43.9 20.3 17.4 37.8 33.4 20.0 45.2 26.1 20.7 25.3 19.8 34.9 34.5 20.1 20.5 29.3 43.4 22.7 27.3 98.1 43.5 31.2 25.7 42.2 26.2 28.8 23.4 44.2 17.1 23.3 20.1 12.6 75.2 90.9 18.9 23.3 48.0 33.6 37.3 18.8 16.0 18.0 16.4 52.9 34.2 32.1 21.4 57.0 44.5 41.8 12.9 25.3 15.9 29.5 67.0 22.4 13.9 55.9 72.4 42.1 42.2 92.1 46.3 43.5 15.3 19.6 88.4 23.1 23.6 39.9 6.1 32.7 41.0 13.6 30.4 27.2 59.4 27.7 19.6 10.8 32.6 22.9 50.2 36.5 29.1 12.8 25.5 41.5 9.9 24.7 16.3 49.5 32.7 22.7 59.0 15.6 17.8 125.7 41.3 95.3 37.5 66.6 45.4 61.9 56.3 50.7 56.1 49.4 41.2 49.4 18.2 59.9 70.9 54.9 118.5 52.8 41.3 41.9 42.8 57.2 42.8 44.9 44.6 43.9 45.2 43.4 43.5 44.2 55.4 28.9 41.5 0.0 18.5 0.0 0.0 0.0 0.0 0.0 36.4 55.4 0.0 0.0 14.2 33.1 0.0 60.3 28.4 0.0 125.2 47.9 0.0 40.5 49.2 15.0 0.0 0.0 0.0 38.8 48.5 24.8 0.0 27.4 40.4 36.1 0.0 0.0 73.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 46.5 0.0 0.0 0.0 0.0 35.5 0.0 0.0 5.4 0.0 0.0 98.9 22.6 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 39.4 18.8 60.9 0.0 0.0 WDFY2 ZFYVE22 ENSG00000139668 "WD repeat and FYVE domain containing 2" Q96P53 13 51584455-51767709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 301.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050094 Supported Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA050094: " "unprognostic (2.95e-1)" "unprognostic (1.78e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-3)" "unprognostic (1.59e-1)" "unprognostic (2.41e-1)" "unprognostic (1.39e-2)" "unprognostic (9.58e-2)" "unprognostic (2.28e-1)" "unprognostic (2.59e-2)" "unprognostic (3.87e-2)" "unprognostic (1.14e-1)" "unprognostic (7.49e-4)" "unprognostic (1.47e-1)" "unprognostic (7.04e-2)" "unprognostic (6.36e-2)" "unprognostic (2.48e-1)" 6.7 11.2 8.9 4.5 12.1 15.0 7.6 9.0 8.8 8.4 4.8 3.9 1.9 5.1 5.5 9.5 6.5 2.9 3.8 8.9 10.4 4.5 6.4 5.4 4.7 11.5 9.9 8.1 17.5 15.0 5.2 5.4 12.4 5.1 2.3 6.0 5.6 4.9 1.6 17.7 4.3 3.6 10.0 7.5 6.5 6.5 10.2 4.4 5.9 3.0 5.1 4.3 8.6 15.4 1.4 2.6 11.3 4.6 5.4 11.2 3.6 11.0 7.0 5.6 4.4 1.7 1.5 4.5 1.0 7.6 3.6 5.0 6.3 19.7 10.6 3.7 3.5 9.6 3.8 13.6 4.3 6.5 4.4 9.1 9.3 12.5 14.2 9.1 2.5 4.8 2.7 2.3 9.3 3.1 4.5 14.8 13.4 3.2 3.7 5.9 4.5 3.0 7.2 3.8 3.1 7.5 3.3 4.9 5.0 9.3 2.3 15.5 9.4 10.6 2.0 5.2 7.8 1.5 2.6 3.2 12.1 6.6 13.3 6.1 7.8 4.0 2.2 8.6 3.1 3.8 2.4 1.9 13.0 4.2 2.1 2.7 5.2 4.0 9.5 11.9 3.5 3.5 8.9 12.1 9.0 8.8 8.9 10.4 11.5 9.9 12.4 10.0 10.2 15.4 16.3 16.0 21.9 118.2 36.9 23.3 20.0 10.2 45.5 35.2 25.7 24.0 7.1 8.6 17.5 29.5 127.2 28.5 41.2 7.0 27.4 19.8 46.3 19.3 23.6 13.0 13.8 17.1 47.1 23.5 33.7 20.7 14.8 20.2 29.7 35.3 27.1 18.1 28.1 37.0 47.1 9.2 8.2 63.8 30.8 19.9 39.4 41.3 12.4 96.5 45.9 26.4 16.5 106.6 301.8 15.0 4.5 21.8 17.1 12.2 9.2 6.4 14.9 52.5 26.3 45.1 27.1 32.3 16.5 46.4 27.1 14.0 27.3 41.7 10.0 16.2 WDR38 ENSG00000136918 "WD repeat domain 38" Q5JTN6 9 124853417-124857890 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "fallopian tube: 77.7" "Cell type enhanced" "Detected in some" "Early spermatids: 26.9;Endometrial ciliated cells: 93.3;Late spermatids: 92.6;Respiratory ciliated cells: 127.9" "Cancer enhanced" "Detected in some" "endometrial cancer: 12.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056607 Approved Vesicles NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA056607: AB_2683188" "unprognostic (5.66e-3)" "unprognostic (2.15e-3)" "unprognostic (1.51e-2)" "prognostic favorable (3.97e-4)" "unprognostic (1.14e-1)" "unprognostic (2.17e-3)" "unprognostic (4.29e-3)" "unprognostic (7.90e-2)" "unprognostic (1.13e-1)" "unprognostic (3.82e-1)" "unprognostic (1.38e-1)" "unprognostic (5.90e-2)" "unprognostic (7.75e-5)" "unprognostic (1.01e-1)" "unprognostic (3.25e-2)" "unprognostic (6.36e-2)" "unprognostic (4.42e-2)" 0.0 0.0 2.1 0.0 2.0 0.0 0.0 2.3 1.3 2.4 16.3 0.0 0.0 0.7 0.0 0.0 77.7 0.0 0.1 2.2 4.0 0.1 0.0 5.2 0.0 8.2 9.8 0.0 0.0 0.0 0.3 0.0 6.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 7.2 0.0 0.0 7.6 3.3 0.1 0.2 0.0 0.0 0.0 0.0 4.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.0 2.3 1.3 2.2 4.0 8.2 9.8 6.5 7.2 3.3 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.2 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 26.9 93.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.2 0.0 0.0 92.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 127.9 0.0 0.0 0.0 2.8 1.6 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 WDR48 "KIAA1449, P80, SPG60" ENSG00000114742 "WD repeat domain 48" Q8TAF3 3 39052013-39096671 "Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 104.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038421, HPA058015" Approved Supported Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA038421: AB_10670780, HPA058015: AB_2683580" "unprognostic (1.95e-1)" "unprognostic (2.14e-1)" "unprognostic (2.99e-2)" "unprognostic (3.78e-1)" "unprognostic (7.68e-2)" "unprognostic (2.34e-3)" "unprognostic (6.14e-3)" "unprognostic (9.87e-3)" "unprognostic (8.02e-2)" "unprognostic (2.22e-2)" "unprognostic (2.28e-1)" "unprognostic (2.14e-2)" "prognostic favorable (1.63e-7)" "unprognostic (2.41e-1)" "unprognostic (2.94e-2)" "unprognostic (1.43e-1)" "unprognostic (1.69e-2)" 14.1 15.5 20.7 13.3 22.2 35.1 17.7 20.3 25.7 17.7 17.1 14.3 15.1 20.0 14.1 14.0 15.7 13.2 16.2 21.9 22.9 21.4 16.1 13.9 17.6 21.2 21.8 21.1 16.1 22.0 4.4 20.8 21.3 16.0 15.1 17.9 15.4 20.9 11.5 14.1 15.1 16.9 21.6 16.1 14.2 47.9 22.8 26.8 24.8 17.1 19.4 16.8 6.3 24.2 11.6 16.4 32.9 23.6 23.8 27.2 14.4 14.4 20.6 17.6 22.5 11.5 12.7 27.8 10.0 20.2 15.7 13.8 30.3 18.7 20.5 70.3 38.8 26.1 22.8 19.0 10.8 18.8 13.7 18.1 21.2 19.0 21.9 31.9 21.8 20.1 30.7 27.8 16.3 9.9 24.6 20.1 36.3 16.8 19.8 9.6 17.3 24.1 21.9 24.2 24.1 29.0 14.7 29.8 25.4 29.0 15.6 26.7 18.8 15.9 12.0 14.7 16.2 30.2 48.6 22.7 18.5 16.9 15.5 13.3 6.0 7.5 9.2 7.9 9.1 9.4 10.6 10.7 8.7 10.9 10.7 9.3 8.0 15.1 13.0 7.2 12.6 8.9 20.7 22.2 20.3 25.7 21.9 22.9 21.2 21.8 21.3 21.6 22.8 24.2 27.0 16.0 22.0 45.4 26.6 17.6 13.3 9.2 20.5 21.6 18.1 16.6 23.2 7.2 15.5 11.0 16.7 15.9 26.0 14.4 17.6 13.9 77.2 20.2 28.5 20.6 22.1 17.9 35.3 12.4 12.2 18.0 9.7 29.7 24.1 25.5 16.1 13.0 8.6 21.9 37.0 13.7 4.1 11.4 15.9 71.9 18.6 16.2 14.2 26.2 19.8 23.6 13.4 38.7 41.1 12.0 12.9 16.6 20.9 21.9 17.3 13.4 17.8 17.9 26.3 21.9 19.2 104.5 59.9 16.7 21.2 21.5 25.7 23.0 12.3 19.5 WDR72 FLJ38736 ENSG00000166415 "WD repeat domain 72" Q3MJ13 15 53513741-53762878 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 105.7;liver: 33.1;thyroid gland: 57.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 12.8;Collecting duct cells: 22.0;Glandular and luminal cells: 13.2;Hepatocytes: 44.3;Proximal tubular cells: 93.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 9.9;OE19: 18.3;RPMI-8226: 17.5;RPTEC TERT1: 10.1;SuSa: 15.2;U-266/70: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048212, HPA057410, HPA059819" Uncertain Approved Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA048212: AB_2680315, HPA057410: AB_2683430, HPA059819: AB_2684133" "unprognostic (6.39e-4)" "unprognostic (1.41e-1)" "unprognostic (3.19e-2)" "unprognostic (1.79e-2)" "unprognostic (2.63e-2)" "unprognostic (3.37e-2)" "unprognostic (5.54e-2)" "unprognostic (2.20e-1)" "unprognostic (1.13e-1)" "unprognostic (1.26e-1)" "unprognostic (2.78e-2)" "unprognostic (1.09e-2)" "prognostic favorable (3.33e-16)" "unprognostic (2.83e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (7.67e-2)" 0.1 0.0 0.1 0.2 0.1 0.0 0.8 0.0 0.1 7.2 0.0 0.6 2.6 1.4 0.5 0.4 2.6 3.9 0.1 0.0 0.1 105.7 33.1 0.8 0.1 0.1 0.4 0.2 3.5 1.8 0.3 0.1 0.1 0.1 0.8 0.7 18.4 0.6 0.0 2.0 0.9 0.0 0.0 0.1 1.1 0.5 0.1 0.0 57.9 0.0 0.0 1.7 0.0 0.3 0.0 9.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 3.2 0.1 6.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.9 18.3 0.1 0.0 0.1 17.5 10.1 3.5 1.9 0.0 0.0 0.1 0.0 15.2 2.4 0.0 0.1 0.3 0.5 0.0 0.1 7.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.1 0.3 0.1 6.4 3.6 0.0 0.5 0.1 1.1 0.0 0.6 0.5 0.0 0.1 0.6 12.8 0.0 22.0 0.0 0.6 0.0 0.2 9.8 3.2 1.2 4.9 1.0 0.1 0.0 0.0 0.4 0.5 2.1 0.2 0.0 13.2 0.0 0.0 0.0 44.3 0.1 3.3 0.5 0.0 0.0 0.6 0.0 0.3 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 93.2 0.1 0.1 0.0 0.0 0.1 1.0 1.6 0.9 0.4 0.1 0.7 0.0 0.3 6.4 WNK3 PRKWNK3 ENSG00000196632 "WNK lysine deficient protein kinase 3" Q9BYP7 X 54192823-54358642 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 11.7;testis: 9.9" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 193.3;Granulosa cells: 199.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.5;AN3-CA: 3.4;HAP1: 5.2;NTERA-2: 9.1;SiHa: 4.5;SuSa: 3.8;U-2 OS: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077678 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA077678: AB_2686850" "unprognostic (1.86e-1)" "unprognostic (1.68e-3)" "unprognostic (2.44e-1)" "unprognostic (7.87e-5)" "unprognostic (4.82e-3)" "unprognostic (1.85e-3)" "unprognostic (1.85e-2)" "unprognostic (3.32e-2)" "unprognostic (3.38e-1)" "unprognostic (3.03e-2)" "unprognostic (5.78e-4)" "unprognostic (2.22e-1)" "unprognostic (2.64e-2)" "unprognostic (5.61e-2)" "unprognostic (9.99e-2)" "unprognostic (7.63e-2)" "unprognostic (8.74e-2)" 0.2 2.5 1.6 0.1 1.7 0.1 0.6 0.3 1.9 0.6 0.0 0.3 0.2 0.5 11.7 0.2 0.8 0.3 0.7 1.0 4.6 1.0 3.6 0.3 0.1 1.6 4.8 3.0 0.3 0.9 2.4 0.3 2.4 0.9 0.0 3.3 0.3 0.8 0.1 0.3 0.2 0.5 0.6 0.2 0.6 9.9 4.5 0.1 0.6 0.1 0.1 0.5 0.4 1.2 0.0 0.0 4.5 3.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 5.2 0.1 0.2 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.1 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 2.2 0.6 0.0 0.9 0.1 1.4 1.3 4.5 0.0 0.5 3.8 0.4 0.0 0.2 0.0 3.9 0.0 1.0 0.0 3.3 0.0 1.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.7 0.3 1.9 1.0 4.6 1.6 4.8 2.4 0.6 4.5 1.2 1.9 0.0 2.3 18.3 0.7 3.7 4.3 0.3 9.1 24.9 5.8 6.9 193.3 2.8 3.2 7.3 14.6 0.2 0.0 0.1 5.9 1.7 6.4 2.0 7.8 8.5 0.0 0.8 14.5 0.0 0.3 6.7 0.0 4.9 6.3 199.5 20.3 48.3 0.1 35.3 29.7 0.0 2.0 0.8 1.5 20.4 15.8 0.6 0.0 3.7 0.0 19.5 0.0 48.2 19.2 0.2 0.0 43.6 0.0 6.0 0.0 3.9 0.2 43.3 6.6 4.8 10.5 43.8 46.3 2.1 1.1 0.1 1.5 9.8 0.0 1.4 WNT2 "INT1L1, IRP" ENSG00000105989 "Wnt family member 2" P09544 7 117275451-117323152 "Cancer-related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 39.9" "Cell type enhanced" "Detected in some" "Early spermatids: 30.9;Endometrial stromal cells: 33.1;Fibroblasts: 82.5;Late spermatids: 14.7;Spermatocytes: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-2197: 11.5" "Region enhanced" "Detected in many" "basal ganglia: 12.6" "Low region specificity" "Detected in many" HPA020920 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA020920: AB_1858850" "unprognostic (1.90e-1)" "unprognostic (6.97e-2)" "unprognostic (2.88e-2)" "unprognostic (4.11e-3)" "unprognostic (9.14e-2)" "unprognostic (2.47e-1)" "unprognostic (2.54e-2)" "unprognostic (2.75e-1)" "unprognostic (2.74e-1)" "unprognostic (5.70e-2)" "unprognostic (1.36e-2)" "unprognostic (1.41e-1)" "unprognostic (3.43e-1)" "unprognostic (4.05e-2)" "unprognostic (2.50e-2)" "unprognostic (1.05e-1)" "unprognostic (2.10e-1)" 1.2 0.0 0.2 0.1 0.4 0.0 0.8 0.1 0.7 3.5 0.3 0.1 0.0 8.6 0.1 0.0 0.8 0.2 0.4 0.4 0.3 0.1 0.5 6.9 0.0 0.1 0.5 0.3 0.1 0.0 0.1 39.9 0.1 3.2 0.0 0.0 0.0 0.4 0.0 0.7 0.0 1.1 0.1 0.9 0.0 0.5 1.5 0.0 0.1 0.0 0.0 1.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 1.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.7 0.4 0.3 0.1 0.5 0.1 0.1 1.5 0.2 0.5 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.0 1.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 30.9 0.8 33.1 9.8 0.0 0.0 1.4 0.0 3.6 82.5 0.0 0.6 0.0 0.0 10.8 0.6 7.7 0.0 0.5 0.0 0.0 0.8 0.3 14.7 1.5 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 13.6 0.5 0.0 2.7 9.0 0.2 0.0 0.0 0.2 WNT3 "INT4, MGC131950, MGC138321, MGC138323" ENSG00000108379 "Wnt family member 3" P56703 17 46762506-46833154 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "liver: 12.3;skin 1: 27.7" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 44.5;Early spermatids: 27.7;Late spermatids: 63.8;Suprabasal keratinocytes: 17.6" "Cancer enriched" "Detected in many" 6 "testis cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 8.5;U-698: 14.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA049893: " "unprognostic (1.84e-1)" "unprognostic (2.90e-2)" "unprognostic (2.35e-1)" "unprognostic (6.41e-4)" "unprognostic (4.73e-2)" "unprognostic (5.26e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (4.97e-2)" "unprognostic (2.20e-2)" "unprognostic (2.16e-1)" "unprognostic (2.66e-1)" "unprognostic (1.10e-8)" "unprognostic (1.77e-1)" "unprognostic (2.08e-1)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" 0.8 0.4 1.3 0.4 1.1 0.1 1.0 0.7 1.0 1.0 0.2 0.6 3.4 0.5 0.0 1.3 0.5 0.1 0.9 0.8 1.2 1.7 12.3 0.9 0.2 1.4 1.8 0.5 0.8 2.5 1.7 0.2 1.2 1.3 0.2 0.2 1.2 0.0 0.2 27.7 2.7 0.2 0.7 0.7 0.4 4.4 4.4 0.1 1.3 0.0 0.1 0.4 1.1 0.7 3.9 1.7 8.5 0.0 0.1 0.1 0.7 0.8 0.9 3.0 0.0 2.7 1.7 1.6 2.3 2.1 6.1 1.3 0.4 0.0 3.9 0.0 0.4 0.0 3.0 2.3 0.0 0.1 0.1 0.2 1.8 1.1 2.3 3.5 1.1 2.5 1.5 0.0 1.0 1.7 0.0 1.4 0.0 1.0 2.4 2.9 1.9 0.2 0.6 0.0 0.1 0.7 1.6 0.0 1.2 2.1 0.0 4.0 0.2 3.2 2.1 0.4 1.5 0.6 0.2 14.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 1.1 0.7 1.0 0.8 1.2 1.4 1.8 1.2 0.7 4.4 0.7 0.2 0.0 1.5 3.9 0.5 44.5 0.6 0.6 3.4 1.1 3.0 1.7 1.3 1.5 0.4 0.0 0.0 2.2 0.1 0.7 1.9 0.7 27.7 0.1 0.7 0.5 0.0 0.0 5.4 2.5 0.1 1.1 0.0 0.2 0.0 0.7 0.4 4.0 0.2 8.4 4.3 0.6 0.0 0.0 1.5 63.8 0.3 0.1 1.8 1.0 0.6 0.2 0.0 4.0 1.1 2.9 1.4 0.4 0.0 1.2 3.7 0.5 0.3 0.8 0.0 1.4 1.1 0.9 2.9 0.8 17.6 0.3 0.0 0.3 0.9 0.3 WNT3A ENSG00000154342 "Wnt family member 3A" P56704 1 228006998-228061271 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 15.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Basal keratinocytes: 3.4;Basal prostatic cells: 3.1;Basal squamous epithelial cells: 8.6;Syncytiotrophoblasts: 2.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HEK 293: 1.1;U-2 OS: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 9: U-2 OS - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049893: " "unprognostic (9.84e-3)" "prognostic favorable (6.11e-5)" "unprognostic (2.40e-1)" "unprognostic (3.37e-1)" "unprognostic (7.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.19e-1)" "unprognostic (1.96e-1)" "unprognostic (4.22e-2)" "unprognostic (4.12e-2)" "unprognostic (2.16e-1)" "unprognostic (4.80e-3)" "unprognostic (1.99e-1)" "unprognostic (7.26e-2)" "unprognostic (5.43e-3)" "unprognostic (1.54e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 1.3 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 3.4 3.1 1.2 8.6 0.0 0.0 0.1 1.9 0.0 0.9 1.8 0.0 2.0 0.0 0.4 0.0 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.5 1.0 2.9 0.0 0.0 0.1 0.5 WNT4 WNT-4 ENSG00000162552 "Wnt family member 4" P56705 1 22117313-22143969 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 40.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 42.1;Breast glandular cells: 19.9;Breast myoepithelial cells: 24.3;Endometrial stromal cells: 71.4;Enteroendocrine cells: 29.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 8.5;SCLC-21H: 10.2;SK-BR-3: 8.6;T-47d: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA011397 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA011397: AB_1858854" "unprognostic (1.85e-1)" "unprognostic (9.08e-2)" "unprognostic (6.67e-3)" "unprognostic (1.75e-2)" "unprognostic (7.17e-2)" "unprognostic (4.30e-3)" "unprognostic (2.77e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.34e-4)" "unprognostic (2.14e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.01e-1)" "unprognostic (2.95e-2)" "unprognostic (4.21e-1)" "unprognostic (2.32e-1)" "unprognostic (4.74e-2)" "unprognostic (9.49e-2)" 0.8 9.0 2.4 0.4 1.5 0.3 2.2 0.2 2.9 8.9 0.5 2.3 3.2 4.5 8.9 12.1 8.3 2.6 0.1 2.0 2.9 1.1 1.4 1.2 0.1 1.6 1.8 16.8 3.0 0.1 5.6 1.6 1.2 5.5 1.6 0.2 4.1 2.6 3.1 40.8 3.1 1.9 1.1 0.3 4.3 0.6 3.9 1.1 3.4 0.6 1.5 3.1 6.3 1.1 1.3 0.1 2.5 0.1 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.8 0.0 0.3 8.5 0.0 0.6 0.0 0.2 0.3 0.3 0.2 0.0 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 1.1 0.2 0.3 0.0 0.0 0.0 1.6 10.2 0.0 0.1 8.6 0.6 0.6 3.4 0.0 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 1.5 0.2 2.9 2.0 2.9 1.6 1.8 1.2 1.1 3.9 1.1 0.9 3.2 8.6 0.3 0.7 16.7 4.3 42.1 6.8 0.0 19.9 24.3 0.6 0.0 15.2 0.0 0.0 0.7 0.1 0.9 0.0 2.7 0.1 4.1 71.4 0.6 29.4 0.0 0.2 0.6 0.1 3.1 0.5 1.6 0.0 0.2 0.7 0.5 0.1 0.0 1.9 16.0 4.1 0.0 0.2 0.9 0.0 0.4 5.4 6.5 0.1 0.0 0.0 0.0 0.3 0.9 0.1 3.8 0.6 5.7 0.3 0.0 12.0 0.0 0.0 0.4 2.2 0.0 0.3 2.5 10.4 0.3 0.6 0.0 0.6 4.2 WNT5B ENSG00000111186 "Wnt family member 5B" Q9H1J7 12 1529891-1647212 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 32.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 25.6;Microglial cells: 19.7;Muller glia cells: 40.4;Urothelial cells: 16.2" "Cancer enhanced" "Detected in all" "testis cancer: 15.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;eosinophil: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 231.4;BJ hTERT+: 143.5;BJ hTERT+ SV40 Large T+: 165.4;BJ hTERT+ SV40 Large T+ RasG12V: 136.4;fHDF/TERT166: 162.6;HBF TERT88: 144.1;hTEC/SVTERT24-B: 144.8;U-138 MG: 142.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061991 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA061991: " "unprognostic (7.44e-2)" "unprognostic (5.59e-2)" "unprognostic (8.14e-2)" "unprognostic (3.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-1)" "unprognostic (5.53e-3)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (4.08e-2)" "unprognostic (2.16e-2)" "unprognostic (1.49e-3)" "unprognostic (1.90e-1)" "unprognostic (2.93e-2)" "unprognostic (2.77e-1)" "unprognostic (2.71e-2)" 3.0 2.3 3.6 4.1 4.1 0.5 3.0 2.8 3.7 5.5 1.8 24.6 4.3 7.2 5.0 14.9 6.2 2.8 4.0 2.8 5.3 1.9 4.6 3.0 2.6 4.7 3.9 8.2 1.5 9.0 11.2 3.9 4.6 32.4 5.8 5.4 15.7 20.0 1.4 5.3 5.0 5.4 3.9 5.2 6.4 1.8 4.2 3.7 2.0 6.7 3.0 13.9 9.7 3.1 0.3 0.1 1.4 0.2 34.6 61.2 0.0 231.4 143.5 165.4 136.4 8.7 0.9 2.9 0.4 162.6 111.1 3.5 3.3 0.0 144.1 55.0 7.9 12.8 0.0 0.0 8.5 0.2 0.1 51.3 3.3 144.8 41.3 66.6 0.0 0.1 9.5 51.9 39.4 0.1 0.0 0.3 5.7 0.2 0.5 0.0 2.3 4.0 2.0 0.0 1.0 3.2 4.9 0.5 0.2 17.7 0.2 0.9 0.0 142.4 5.9 56.7 119.7 13.9 2.2 0.7 13.9 0.0 1.5 0.0 1.8 1.5 0.0 0.8 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 3.6 4.1 2.8 3.7 2.8 5.3 4.7 3.9 4.6 3.9 4.2 3.1 0.9 0.0 0.6 7.5 1.5 0.9 11.0 1.9 25.6 1.8 0.7 6.5 2.2 0.0 3.3 0.0 0.0 1.0 0.2 2.4 0.0 1.1 0.2 1.7 10.4 1.4 0.0 0.0 6.9 0.7 1.1 8.0 0.5 2.7 0.0 0.3 0.4 1.7 5.3 0.0 7.9 1.9 2.0 2.1 2.9 0.5 2.1 2.7 3.6 19.7 4.1 40.4 0.0 4.0 5.6 2.8 5.0 2.6 4.5 8.8 1.0 0.2 4.3 2.7 6.6 7.9 4.3 0.7 5.7 7.7 1.3 0.7 0.2 0.0 1.7 16.2 XKR4 KIAA1889 ENSG00000206579 "XK related 4" Q5GH76 8 55102028-55542054 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 8.1" "Group enriched" "Detected in some" 19 "Excitatory neurons: 306.3;Inhibitory neurons: 1019.5;Oligodendrocyte precursor cells: 721.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "REH: 2.6;RPTEC TERT1: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025072, HPA028083" Uncertain Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA025072: AB_1858886, HPA028083: AB_10601025" "unprognostic (7.15e-4)" "unprognostic (1.28e-3)" "unprognostic (6.98e-2)" "unprognostic (5.63e-3)" "unprognostic (7.39e-2)" "unprognostic (5.68e-3)" "unprognostic (6.33e-2)" "unprognostic (5.14e-2)" "unprognostic (1.88e-1)" "unprognostic (2.63e-1)" "unprognostic (2.38e-3)" "unprognostic (6.63e-2)" "unprognostic (3.46e-4)" "unprognostic (2.08e-2)" "unprognostic (2.39e-2)" "unprognostic (7.36e-2)" "unprognostic (4.96e-2)" 0.1 0.2 7.6 0.5 7.1 0.0 0.0 0.9 8.1 0.3 0.0 1.7 0.2 0.1 0.2 0.5 0.1 0.2 0.7 7.0 2.2 0.1 0.0 0.0 0.4 0.1 2.2 0.0 0.2 0.0 0.7 0.0 0.0 0.3 0.4 0.6 0.3 0.5 0.0 0.2 0.3 0.1 0.0 0.1 0.3 0.1 5.8 0.5 0.0 0.0 0.4 0.3 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.6 0.0 0.0 9.9 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.6 7.1 0.9 8.1 7.0 2.2 0.1 2.2 0.0 0.0 5.8 1.1 0.5 9.6 18.7 7.8 0.1 0.4 0.6 0.0 0.6 12.5 0.1 0.3 2.1 0.0 9.3 3.7 35.5 0.1 0.4 0.1 0.0 0.1 0.9 0.6 0.2 2.4 0.0 0.0 306.3 0.9 0.1 2.3 0.0 1.1 0.0 0.2 1.1 0.4 0.1 0.0 1019.5 0.0 0.0 0.0 1.0 0.0 0.0 1.4 8.8 30.0 1.8 0.6 0.0 721.3 9.4 0.4 0.0 0.0 0.4 0.6 0.0 0.1 5.2 1.6 0.0 2.6 0.4 1.1 0.1 0.2 0.9 0.1 0.5 0.1 0.0 0.7 YIPF6 "FinGER6, MGC21416" ENSG00000181704 "Yip1 domain family member 6" Q96EC8 X 68498562-68537282 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 278.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003720 Uncertain Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA003720: AB_1080626" "unprognostic (5.07e-3)" "unprognostic (2.13e-1)" "unprognostic (1.53e-1)" "unprognostic (1.72e-1)" "unprognostic (7.17e-2)" "unprognostic (5.90e-3)" "unprognostic (1.64e-1)" "unprognostic (1.28e-1)" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (1.33e-2)" "unprognostic (3.15e-1)" "unprognostic (8.85e-3)" "unprognostic (8.48e-2)" "unprognostic (2.90e-2)" "unprognostic (3.25e-1)" "unprognostic (6.32e-2)" 14.3 14.7 13.9 7.8 15.7 6.6 14.9 15.6 15.4 14.5 15.4 12.5 11.7 13.3 14.5 11.6 13.2 11.1 11.6 12.9 16.0 18.9 21.6 12.4 6.4 15.9 16.5 10.5 14.5 20.6 15.0 18.2 14.9 19.9 14.1 14.3 16.4 14.5 16.9 10.7 11.4 12.9 15.1 8.3 15.3 6.2 15.7 6.7 21.8 16.4 7.4 12.4 8.4 15.5 23.5 22.4 22.6 7.9 28.7 17.8 24.8 18.0 22.5 13.8 17.4 23.5 23.5 0.1 32.6 15.1 22.8 18.2 29.8 12.2 23.2 6.8 20.2 10.4 22.6 19.6 26.4 11.4 14.3 17.6 22.3 20.5 25.4 24.1 13.8 13.4 16.6 22.3 18.8 24.8 6.6 9.7 24.0 34.0 23.3 6.7 27.5 12.3 22.9 25.9 23.5 24.6 30.6 20.9 21.7 20.4 12.9 11.8 18.8 15.4 14.8 49.2 35.0 12.2 15.0 4.6 22.8 17.2 26.1 5.3 4.0 4.7 2.2 4.7 1.5 3.9 2.2 2.0 3.0 2.1 2.2 1.9 10.5 2.9 4.2 3.6 2.6 2.8 13.9 15.7 15.6 15.4 12.9 16.0 15.9 16.5 14.9 15.1 15.7 15.5 42.1 70.5 99.6 25.5 25.6 34.9 62.3 110.0 21.6 54.6 47.4 32.3 33.7 32.9 88.6 57.0 47.9 101.6 19.8 43.8 35.2 47.4 25.9 50.9 35.2 41.7 54.4 80.4 18.8 43.9 111.3 53.1 27.5 47.8 53.7 33.6 42.1 60.2 44.1 45.4 21.9 61.8 93.6 25.9 42.0 63.2 42.6 38.5 35.6 23.4 23.4 63.5 29.9 26.7 34.9 47.3 34.7 47.4 42.7 90.4 42.4 62.4 81.6 52.7 26.3 50.8 44.6 31.5 28.1 31.4 43.3 278.8 29.0 29.6 33.5 89.5 ZBTB39 "KIAA0352, ZNF922" ENSG00000166860 "Zinc finger and BTB domain containing 39" O15060 12 56998836-57006546 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 16.7;Early spermatids: 19.9;Horizontal cells: 21.9;Late spermatids: 20.3;Spermatogonia: 17.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "RH-30: 46.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016866, HPA020306" Uncertain Approved Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Vesicles "HPA016866: AB_2669470, HPA020306: AB_2670406" "unprognostic (2.06e-2)" "unprognostic (1.61e-1)" "unprognostic (8.92e-2)" "unprognostic (2.90e-2)" "unprognostic (3.07e-1)" "unprognostic (2.68e-2)" "unprognostic (4.10e-3)" "unprognostic (1.69e-1)" "unprognostic (1.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-3)" "unprognostic (1.76e-1)" "unprognostic (2.34e-1)" "unprognostic (5.74e-2)" "unprognostic (3.46e-1)" "unprognostic (2.54e-2)" "unprognostic (7.00e-2)" 2.6 1.5 1.7 2.9 2.0 5.8 2.8 2.2 2.0 2.1 0.9 2.5 2.2 3.2 2.5 2.4 3.1 1.8 2.2 1.6 1.8 2.1 3.4 2.7 3.9 1.9 2.0 4.4 2.9 3.3 1.1 3.7 1.9 2.6 2.3 2.9 2.6 3.3 2.5 2.9 2.9 2.8 1.5 4.2 2.6 7.1 2.0 4.2 2.5 2.7 3.6 2.1 1.7 2.3 3.4 5.5 15.3 7.9 3.4 3.6 10.1 3.2 4.1 5.2 3.7 5.7 2.3 10.8 4.2 3.2 3.3 4.5 11.8 5.0 5.0 5.0 8.2 12.1 3.6 4.6 3.2 9.3 9.6 2.8 4.8 4.1 6.6 5.6 6.0 12.2 15.2 9.7 3.8 3.9 13.7 7.8 15.2 3.5 4.6 13.0 46.9 5.2 2.4 6.7 7.5 9.7 4.7 6.0 4.7 14.2 5.1 10.1 4.8 4.3 9.5 2.0 4.1 12.5 8.7 11.5 2.7 5.2 2.7 0.7 0.3 0.0 0.4 0.2 0.4 0.3 0.4 0.6 0.4 0.4 0.3 0.6 0.0 0.7 0.0 0.5 0.1 0.3 1.7 2.0 2.2 2.0 1.6 1.8 1.9 2.0 1.9 1.5 2.0 2.3 2.9 0.0 0.6 3.3 3.5 1.5 2.3 1.6 7.4 11.6 1.7 1.5 3.5 2.8 1.9 0.0 16.7 3.1 3.0 0.9 0.0 1.5 19.9 1.2 3.3 4.3 1.2 2.1 1.8 1.8 1.8 2.3 1.5 1.2 1.3 3.6 8.6 2.5 1.9 21.9 1.8 2.5 2.0 3.0 2.0 20.3 1.8 1.4 1.8 0.0 3.6 1.8 3.1 1.5 2.8 2.5 3.2 5.7 3.2 3.5 1.5 1.4 3.1 7.4 6.6 3.4 2.2 10.1 17.6 3.2 1.6 2.2 2.1 1.9 2.4 1.4 ZC3H10 "FLJ14451, ZC3HDC10" ENSG00000135482 "Zinc finger CCCH-type containing 10" Q96K80 12 56118260-56127514 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039236, HPA062265" Uncertain Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA039236: AB_10795463, HPA062265: AB_2684730" "unprognostic (1.19e-1)" "unprognostic (1.53e-1)" "unprognostic (2.97e-1)" "unprognostic (7.39e-2)" "unprognostic (2.27e-1)" "unprognostic (3.35e-2)" "unprognostic (2.95e-2)" "unprognostic (1.53e-2)" "unprognostic (2.07e-2)" "unprognostic (2.80e-1)" "unprognostic (1.31e-5)" "unprognostic (4.42e-2)" "unprognostic (2.69e-2)" "unprognostic (6.45e-2)" "unprognostic (1.40e-1)" "unprognostic (2.58e-2)" "unprognostic (1.21e-1)" 2.8 3.1 1.9 3.0 2.8 1.4 2.5 3.4 2.4 3.8 1.1 3.6 1.6 3.9 2.2 1.9 3.3 1.7 2.5 1.9 2.1 2.3 2.9 2.4 2.9 2.9 2.5 4.1 3.6 2.5 2.4 2.0 2.7 2.6 1.3 4.0 2.8 2.4 5.0 2.4 2.3 2.0 2.1 3.9 2.4 8.7 2.7 2.9 2.6 3.1 2.2 3.3 2.6 4.0 3.3 5.8 4.6 3.6 5.5 3.7 3.5 3.9 2.6 2.3 1.8 1.6 1.9 3.7 6.3 2.8 1.3 4.4 2.4 1.4 1.5 6.3 6.1 5.5 5.8 1.7 3.4 5.4 3.3 2.4 3.1 2.7 3.1 4.3 3.5 4.2 2.9 6.5 3.1 2.4 5.6 2.1 3.1 1.9 4.7 5.5 5.0 3.4 1.9 1.6 4.4 4.3 2.3 3.4 3.5 3.4 5.6 4.5 5.0 2.2 5.1 4.3 2.9 5.4 3.7 2.0 2.9 2.4 5.4 3.6 5.0 5.9 4.7 6.0 4.9 3.6 3.7 4.1 5.3 3.9 3.7 3.6 3.6 8.0 10.5 2.4 2.0 3.7 1.9 2.8 3.4 2.4 1.9 2.1 2.9 2.5 2.7 2.1 2.7 4.0 4.2 0.0 4.2 1.3 5.6 0.8 2.5 1.3 1.8 9.0 3.2 2.2 3.0 5.7 0.8 7.3 20.9 6.3 5.9 7.1 15.6 5.3 47.6 2.2 4.3 5.1 1.2 5.2 0.6 3.0 2.7 3.3 1.1 2.6 2.5 5.9 6.8 3.0 5.3 13.5 0.9 3.8 2.0 7.4 1.6 9.5 5.3 4.0 3.6 1.0 10.6 9.2 9.2 0.0 1.5 3.3 2.3 5.3 1.6 2.3 6.0 4.7 2.7 17.3 0.0 6.2 5.3 16.2 15.5 1.9 1.7 6.4 3.2 5.1 3.9 1.4 ZCCHC18 "PNMA7B, SIZN2" ENSG00000166707 "Zinc finger CCHC-type containing 18" P0CG32 X 104112131-104115842 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 5.0;ovary: 4.2" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 4.2;NK-cells: 9.2;Oligodendrocyte precursor cells: 6.6;Sertoli cells: 6.6" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.5;Karpas-707: 4.6;SH-SY5Y: 3.1" "Low region specificity" "Detected in all" "HPA034940, HPA078516" Uncertain Approved Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA034940: AB_10671098, HPA078516: " "unprognostic (7.20e-2)" "unprognostic (7.71e-4)" "unprognostic (8.29e-2)" "unprognostic (4.21e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-3)" "unprognostic (2.20e-2)" "unprognostic (3.22e-2)" "unprognostic (7.59e-2)" "unprognostic (3.34e-1)" "unprognostic (4.44e-6)" "unprognostic (4.05e-2)" "unprognostic (1.02e-6)" "unprognostic (3.82e-2)" "unprognostic (4.02e-1)" "unprognostic (3.91e-2)" "unprognostic (4.14e-3)" 0.5 0.8 3.0 1.3 2.9 0.4 0.3 2.9 3.0 1.8 1.1 0.7 0.3 1.5 0.2 0.3 1.3 0.4 0.5 2.7 5.0 0.4 0.1 0.4 2.0 2.2 2.5 4.2 0.9 0.0 1.6 0.1 2.2 0.8 0.3 1.2 0.2 0.6 0.1 0.2 2.0 0.6 2.4 2.2 0.5 1.0 4.9 0.4 0.3 0.1 2.0 0.6 0.7 2.1 0.0 0.1 1.9 1.3 0.1 0.0 0.1 0.4 0.0 0.3 0.3 0.1 0.0 2.5 0.0 0.1 0.4 0.0 1.1 0.0 0.1 0.7 0.9 0.4 0.1 0.0 0.2 1.4 0.4 0.1 0.0 0.2 0.0 1.1 0.3 0.1 0.0 4.6 0.1 0.0 0.0 0.0 1.0 0.0 0.3 1.7 0.4 0.0 0.2 0.2 1.3 3.1 0.1 0.0 0.0 0.2 0.0 0.1 0.8 0.1 0.5 0.1 0.6 0.1 0.0 1.2 0.0 1.4 0.4 0.0 0.0 0.0 0.4 0.0 0.6 0.7 0.3 0.5 0.0 0.8 0.3 0.4 0.0 0.0 0.0 0.0 0.2 0.1 3.0 2.9 2.9 3.0 2.7 5.0 2.2 2.5 2.2 2.4 4.9 2.1 0.9 0.0 0.6 3.3 4.0 0.1 0.2 0.0 0.0 0.8 0.3 0.3 0.7 0.0 1.3 1.8 0.0 0.0 1.7 0.0 0.0 0.1 0.1 0.6 0.9 1.2 4.2 0.8 2.6 0.2 0.0 1.2 0.0 0.3 0.0 1.3 0.7 0.0 0.0 1.7 1.5 0.0 0.0 0.3 0.4 0.3 1.5 0.1 1.8 0.0 0.1 3.4 9.2 6.6 0.3 0.0 0.0 1.2 1.7 0.1 0.0 0.2 1.5 1.0 6.6 0.2 2.4 0.0 0.2 0.1 0.0 0.0 3.6 1.0 0.0 0.1 ZCCHC3 "C20orf99, dJ1103G7.7" ENSG00000247315 "Zinc finger CCHC-type containing 3" Q9NUD5 20 297570-300321 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042972 Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA042972: AB_10959663" "unprognostic (5.98e-3)" "unprognostic (1.38e-1)" "unprognostic (1.26e-2)" "unprognostic (1.01e-3)" "unprognostic (2.13e-1)" "unprognostic (3.04e-1)" "unprognostic (1.30e-2)" "unprognostic (1.90e-1)" "unprognostic (3.29e-1)" "unprognostic (6.55e-2)" "prognostic favorable (1.29e-4)" "unprognostic (4.30e-1)" "unprognostic (3.34e-3)" "unprognostic (6.33e-2)" "unprognostic (1.88e-1)" "unprognostic (3.67e-1)" "unprognostic (1.74e-2)" 9.9 11.3 14.5 11.7 14.1 17.8 8.4 15.8 16.8 10.8 15.9 8.9 9.8 11.2 12.5 6.8 13.0 8.3 9.8 13.5 19.5 10.9 10.0 8.6 17.7 14.8 15.7 18.2 10.8 11.7 10.9 20.1 15.1 9.2 7.5 8.5 8.8 10.7 9.8 6.1 11.4 8.1 13.2 15.4 10.3 9.6 17.7 23.1 8.9 12.6 15.7 9.8 6.3 14.2 24.0 18.4 56.7 28.4 18.3 18.6 33.6 14.7 16.2 16.2 16.7 28.4 14.0 21.8 9.6 9.5 16.7 32.6 29.2 16.5 15.3 11.8 26.8 44.1 9.3 90.0 21.2 50.9 11.7 18.2 19.2 9.9 11.7 16.8 26.2 24.4 55.7 21.5 12.7 10.6 38.8 62.1 50.7 23.3 19.6 56.5 27.1 27.7 14.4 15.2 23.5 34.7 17.5 34.9 46.8 24.2 16.0 93.8 11.4 16.6 16.3 6.8 17.8 39.1 53.9 42.3 6.0 32.4 16.3 2.5 1.2 2.2 1.6 0.7 1.5 1.7 1.4 1.3 0.9 2.1 1.6 1.6 0.4 1.1 0.5 2.1 1.4 0.8 14.5 14.1 15.8 16.8 13.5 19.5 14.8 15.7 15.1 13.2 17.7 14.2 17.3 0.0 9.1 8.8 12.6 15.8 22.7 3.5 11.4 26.9 16.1 12.8 7.6 17.2 4.9 9.2 8.4 22.4 22.3 13.0 3.9 5.9 0.7 22.6 28.0 16.4 21.0 17.9 6.8 5.4 13.4 14.5 8.2 14.9 0.0 16.1 19.2 10.2 11.0 37.0 8.0 16.2 4.1 9.8 9.7 2.1 17.4 11.5 12.4 8.4 11.0 19.6 8.2 7.1 12.3 5.2 10.3 10.5 8.9 16.3 12.2 6.8 8.9 22.1 6.6 14.2 12.3 5.8 7.6 7.2 5.7 20.7 11.1 21.2 13.3 16.0 ZDHHC14 "FLJ20984, NEW1CP" ENSG00000175048 "Zinc finger DHHC-type palmitoyltransferase 14" Q8IZN3 6 157381133-157678157 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 161.7;Horizontal cells: 122.8;Inhibitory neurons: 108.1;Oligodendrocyte precursor cells: 315.2;Oligodendrocytes: 221.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 4 "HDLM-2: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013437, HPA063754" Approved Uncertain Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA013437: , HPA063754: AB_2685113" "unprognostic (1.66e-2)" "unprognostic (1.27e-2)" "unprognostic (1.58e-2)" "unprognostic (3.98e-2)" "unprognostic (1.59e-1)" "unprognostic (6.78e-3)" "unprognostic (1.84e-1)" "unprognostic (6.02e-2)" "unprognostic (2.87e-2)" "unprognostic (1.63e-1)" "prognostic favorable (6.93e-4)" "unprognostic (3.94e-2)" "unprognostic (5.01e-3)" "unprognostic (1.89e-1)" "unprognostic (7.95e-2)" "unprognostic (4.43e-1)" "unprognostic (2.63e-1)" 2.9 1.6 7.3 1.8 7.6 2.5 1.6 9.7 6.8 5.3 1.1 2.4 2.8 12.4 0.4 1.7 2.0 2.3 5.2 7.5 5.1 4.6 4.4 3.0 2.4 12.5 9.1 1.4 2.5 5.6 1.6 2.2 10.9 3.5 1.7 1.3 2.1 1.4 2.3 1.4 4.1 6.1 13.5 3.1 3.8 3.3 10.8 0.9 1.7 3.9 2.4 2.4 1.9 22.7 2.6 2.7 0.8 3.8 2.0 1.5 8.7 4.1 3.7 2.8 2.5 3.3 1.9 6.4 1.4 3.3 5.4 1.3 2.2 2.2 2.5 50.9 3.2 12.7 1.0 1.5 2.7 1.7 2.8 1.1 2.3 2.9 1.2 2.4 4.3 2.8 10.4 4.7 1.6 1.7 1.1 4.2 1.6 5.1 3.2 0.2 0.4 3.9 5.8 1.1 6.3 1.9 4.8 3.1 3.5 1.6 0.4 2.0 6.0 4.2 3.1 8.3 5.2 1.1 1.3 0.9 1.5 4.5 4.7 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.1 7.3 7.6 9.7 6.8 7.5 5.1 12.5 9.1 10.9 13.5 10.8 22.7 23.4 3.2 0.0 45.4 9.8 12.9 2.1 3.0 4.0 25.3 5.8 8.0 18.3 12.8 1.4 7.3 6.2 12.5 11.2 7.4 11.7 7.5 10.7 5.0 16.6 15.1 2.4 4.2 161.7 3.1 2.2 11.4 6.1 9.4 0.0 7.7 22.5 23.1 11.4 122.8 108.1 9.8 6.1 15.5 6.7 5.9 8.1 8.8 10.6 65.6 3.8 5.4 7.2 315.2 221.0 2.7 8.5 10.1 4.5 14.2 6.0 3.8 0.4 6.0 0.0 6.2 8.4 7.2 10.0 1.5 8.4 21.1 6.6 4.6 11.5 2.7 ZNF37A "KOX21, ZNF37" ENSG00000075407 "Zinc finger protein 37A" P17032 10 38094334-38150293 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003172 Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA003172: AB_1080709" "unprognostic (8.64e-2)" "unprognostic (1.24e-1)" "unprognostic (3.22e-1)" "unprognostic (6.87e-2)" "unprognostic (1.17e-2)" "unprognostic (2.31e-2)" "prognostic unfavorable (2.83e-4)" "unprognostic (7.65e-3)" "unprognostic (2.47e-1)" "unprognostic (3.54e-2)" "unprognostic (1.02e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (4.39e-2)" "unprognostic (1.29e-1)" "unprognostic (3.43e-2)" "unprognostic (3.09e-2)" 4.9 5.6 5.9 6.2 6.0 3.1 5.7 11.3 7.8 6.3 4.3 5.6 4.8 7.2 5.8 3.7 5.2 4.5 4.3 6.3 8.0 5.8 4.9 4.8 5.9 5.5 5.0 7.5 8.7 9.7 8.6 4.8 5.9 5.7 4.8 16.6 7.6 5.6 3.7 6.3 4.6 5.6 3.6 6.0 5.6 2.4 6.7 5.8 8.1 5.1 6.0 4.4 4.2 8.8 15.8 7.9 7.0 13.2 10.5 10.2 7.6 11.9 4.5 5.4 7.2 6.4 4.5 23.1 3.5 6.6 7.4 6.3 13.2 10.0 8.4 14.9 12.5 23.3 9.7 9.1 9.0 24.7 14.4 7.8 16.4 9.3 7.7 10.8 7.2 10.8 15.4 15.9 11.7 3.7 14.0 3.7 6.1 5.5 13.0 10.0 19.0 4.6 5.7 6.1 5.6 9.6 8.2 6.6 6.7 7.4 12.1 7.6 12.4 10.1 10.9 9.8 11.6 17.8 20.5 8.9 6.7 17.3 6.5 1.3 1.0 1.0 1.5 0.8 2.0 1.5 1.8 1.6 1.0 2.6 2.1 1.8 0.7 2.7 2.3 1.2 1.1 0.7 5.9 6.0 11.3 7.8 6.3 8.0 5.5 5.0 5.9 3.6 6.7 8.8 21.8 25.6 43.6 31.6 26.0 8.2 14.7 11.0 18.8 66.1 14.4 16.4 29.6 15.7 18.8 11.0 54.2 10.2 23.2 7.6 1.9 18.1 3.7 15.0 30.0 26.3 41.9 26.3 46.7 11.8 6.8 27.0 16.3 14.9 40.5 56.9 22.9 10.4 7.1 42.1 57.7 10.4 10.2 11.3 6.4 1.4 28.3 13.8 5.4 40.3 16.6 27.4 30.9 64.3 85.5 11.9 8.3 28.2 34.4 17.0 12.6 7.3 12.6 55.1 13.1 53.5 25.7 22.2 15.2 14.7 6.0 3.8 18.5 48.5 12.5 9.3 ZNF530 KIAA1508 ENSG00000183647 "Zinc finger protein 530" Q6P9A1 19 57599885-57612722 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 8.6;Muller glia cells: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HEK 293: 75.0;U-266/84: 58.8" HPA045868 Uncertain Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA045868: AB_2679478" "unprognostic (1.57e-1)" "unprognostic (3.02e-3)" "unprognostic (5.65e-2)" "unprognostic (2.90e-2)" "unprognostic (3.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.54e-2)" "unprognostic (6.80e-2)" "unprognostic (9.69e-3)" "unprognostic (4.98e-3)" "unprognostic (3.19e-2)" "unprognostic (7.84e-3)" "unprognostic (1.47e-1)" "unprognostic (1.70e-1)" "unprognostic (3.11e-1)" "unprognostic (1.86e-2)" "unprognostic (1.06e-1)" 1.5 1.4 4.5 1.2 4.2 3.2 1.6 6.8 5.4 0.7 5.6 1.1 1.0 1.0 1.9 0.9 0.7 0.7 4.0 4.6 4.2 1.1 0.8 0.9 2.0 4.3 3.7 0.9 1.5 0.8 0.7 1.2 4.0 1.4 0.8 2.6 1.2 1.4 6.3 2.2 1.0 0.7 3.8 2.2 1.8 1.2 4.0 2.3 1.0 2.7 2.3 1.0 0.7 4.8 6.7 5.8 4.3 3.7 0.3 1.9 6.8 4.1 1.7 6.8 3.8 4.1 1.0 0.8 3.3 1.5 4.1 2.2 3.6 3.0 7.2 0.2 75.0 13.4 11.6 2.6 0.5 4.9 6.1 1.3 1.7 6.4 1.8 1.9 1.5 4.7 1.7 3.0 2.3 2.6 7.0 3.8 6.4 0.5 14.2 0.9 13.6 6.3 1.3 11.3 4.9 4.5 4.8 1.2 1.4 3.8 3.1 7.6 2.0 8.5 5.3 1.9 8.5 14.6 58.8 9.3 5.2 5.2 6.0 1.0 1.5 1.0 3.0 0.9 2.2 3.5 2.0 3.1 1.8 2.5 2.7 2.2 1.7 3.1 1.1 1.7 2.9 1.6 4.5 4.2 6.8 5.4 4.6 4.2 4.3 3.7 4.0 3.8 4.0 4.8 2.7 6.4 1.5 1.6 2.3 1.8 0.7 1.7 1.8 3.3 1.8 1.0 8.6 1.5 0.9 0.0 0.0 2.0 3.1 0.6 1.9 1.9 0.3 0.9 0.8 2.7 0.0 4.0 1.4 2.9 1.5 1.4 1.1 0.8 2.5 2.2 2.9 0.7 2.0 0.0 1.0 0.2 2.0 0.8 2.0 0.3 0.9 0.6 5.4 0.0 1.5 9.1 2.1 0.5 0.9 1.4 1.7 1.5 2.5 1.3 0.9 0.8 0.7 4.2 6.6 1.5 1.7 2.1 2.9 1.6 1.7 1.4 2.3 1.1 1.0 0.9 ZNF563 FLJ34797 ENSG00000188868 "Zinc finger protein 563" Q8TA94 19 12317477-12333720 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 14.5" "Cell type enriched" "Detected in many" 6 "Early spermatids: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.2;T-cells: 8.9" "Cell line enhanced" "Detected in many" "Hep G2: 9.0" HPA042136 Uncertain Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA042136: AB_10795395" "unprognostic (1.40e-1)" "unprognostic (3.61e-1)" "unprognostic (1.02e-1)" "unprognostic (8.81e-2)" "unprognostic (9.88e-2)" "unprognostic (2.49e-1)" "unprognostic (1.20e-1)" "unprognostic (9.16e-4)" "unprognostic (1.02e-2)" "unprognostic (5.38e-2)" "unprognostic (3.36e-2)" "unprognostic (1.51e-1)" "unprognostic (2.29e-3)" "unprognostic (9.90e-2)" "unprognostic (2.12e-1)" "unprognostic (1.27e-3)" "unprognostic (1.18e-2)" 2.5 2.8 1.9 2.0 1.9 1.1 3.8 3.1 1.9 3.3 1.6 2.1 1.4 2.1 2.2 2.4 3.1 1.5 3.9 1.9 1.2 3.8 10.0 1.9 2.8 1.7 1.4 3.5 2.1 2.5 2.2 1.1 1.8 4.9 2.1 2.7 2.7 2.6 1.9 3.9 2.2 2.0 0.9 2.6 1.8 14.5 1.8 3.0 5.5 3.0 3.0 2.7 3.2 2.7 2.0 0.2 0.7 2.7 2.8 1.8 0.2 2.3 4.5 2.8 4.1 2.6 0.7 4.6 2.4 2.9 3.1 1.6 2.4 5.4 2.5 0.1 0.4 0.6 0.5 9.0 2.2 0.4 2.8 3.0 3.7 2.8 1.9 2.1 0.1 2.5 0.9 1.0 2.5 1.3 2.5 0.9 1.1 1.0 2.0 0.1 2.0 0.1 3.0 2.7 0.7 1.3 0.3 0.5 0.3 3.1 2.2 0.2 0.3 4.4 0.8 5.1 1.4 4.4 3.8 0.3 0.8 0.4 1.6 0.8 1.1 0.7 2.7 1.2 1.6 3.2 4.6 2.5 1.4 4.2 8.9 5.2 0.8 1.5 1.4 1.4 3.9 2.2 1.9 1.9 3.1 1.9 1.9 1.2 1.7 1.4 1.8 0.9 1.8 2.7 3.2 3.2 1.7 2.3 4.6 1.3 2.0 3.0 4.6 8.4 2.4 3.4 5.5 5.7 2.1 1.8 0.0 0.3 2.6 1.1 1.9 4.7 200.4 3.6 2.3 3.7 0.0 19.4 4.2 4.9 0.2 2.6 2.0 2.0 0.0 9.5 3.3 8.3 2.2 5.0 2.6 2.4 2.0 1.9 0.4 32.3 7.8 1.7 5.4 3.7 1.8 13.9 8.2 3.5 2.7 2.6 4.5 5.7 1.5 2.0 2.6 7.8 4.9 3.4 13.1 3.1 3.3 15.8 6.3 2.8 2.0 0.1 4.7 3.3 2.5 0.9 ZNF624 KIAA1349 ENSG00000197566 "Zinc finger protein 624" Q9P2J8 17 16620734-16653856 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 16.6;Oligodendrocytes: 21.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SuSa: 12.1" "Low region specificity" "Detected in all" "HPA023157, HPA023244" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA023157: AB_2671094, HPA023244: AB_2671117" "unprognostic (2.47e-1)" "unprognostic (8.75e-2)" "unprognostic (3.51e-2)" "unprognostic (3.97e-3)" "unprognostic (1.64e-1)" "unprognostic (3.77e-2)" "unprognostic (1.24e-1)" "unprognostic (2.18e-1)" "unprognostic (1.10e-2)" "unprognostic (4.76e-2)" "unprognostic (1.40e-1)" "unprognostic (1.62e-1)" "unprognostic (1.75e-2)" "unprognostic (1.52e-1)" "unprognostic (7.88e-2)" "unprognostic (1.09e-1)" "unprognostic (2.97e-1)" 1.6 0.7 1.3 1.5 2.2 1.1 1.8 1.4 2.5 2.3 0.3 1.7 1.3 2.5 1.2 1.3 2.0 1.2 1.5 1.2 1.8 1.8 0.8 2.0 2.4 2.5 1.9 3.6 0.8 2.5 0.4 3.0 2.1 1.0 1.8 2.6 0.9 1.5 0.4 1.5 1.4 2.0 1.8 3.5 1.9 4.8 2.5 3.1 2.3 0.9 2.1 1.4 0.9 4.1 1.1 1.8 5.3 1.8 2.6 3.1 1.4 1.8 3.1 3.4 3.1 0.9 1.0 2.7 1.5 2.4 1.1 1.5 1.5 1.9 3.7 2.9 1.8 3.0 0.9 0.8 2.5 2.1 2.9 3.5 4.4 1.9 3.8 1.8 3.1 3.4 1.9 0.7 4.5 1.6 5.2 0.8 0.9 3.8 0.8 5.5 9.0 0.8 2.3 2.2 1.6 3.2 2.0 1.5 2.1 12.1 1.2 0.9 4.4 3.2 1.2 1.2 1.3 1.2 0.9 0.0 1.5 0.0 2.7 1.0 1.0 2.0 1.7 3.3 2.5 1.6 2.0 2.0 1.9 2.9 2.2 1.3 0.2 2.8 1.5 0.5 1.5 1.1 1.3 2.2 1.4 2.5 1.2 1.8 2.5 1.9 2.1 1.8 2.5 4.1 4.2 0.0 0.0 5.9 2.9 0.5 0.4 1.1 0.6 5.1 1.4 1.0 2.6 1.5 2.2 0.0 2.1 1.3 2.4 1.9 3.9 1.3 11.2 1.3 4.1 3.0 0.0 1.7 5.6 1.0 1.5 2.7 1.5 1.4 3.8 4.1 4.6 0.3 2.6 8.4 9.6 1.3 0.0 4.6 1.6 2.1 1.5 2.3 0.0 8.4 1.2 2.8 2.1 16.6 21.1 1.5 0.8 2.6 0.6 0.5 0.8 2.0 3.6 3.2 0.0 2.4 4.1 12.0 8.4 0.9 0.9 1.5 2.3 4.6 0.9 1.1 ZNF644 "BM-005, KIAA1221, MGC60165, MGC70410" ENSG00000122482 "Zinc finger protein 644" Q9H582 1 90915298-91022272 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 262.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057795 Uncertain Uncertain Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Vesicles "HPA057795: AB_2683529" "unprognostic (8.20e-2)" "unprognostic (5.86e-3)" "prognostic favorable (4.27e-4)" "prognostic unfavorable (8.39e-4)" "unprognostic (3.19e-3)" "unprognostic (4.62e-3)" "unprognostic (8.04e-2)" "unprognostic (7.01e-2)" "unprognostic (2.44e-2)" "unprognostic (6.32e-2)" "unprognostic (1.70e-1)" "unprognostic (1.16e-1)" "unprognostic (2.61e-2)" "unprognostic (3.03e-1)" "unprognostic (5.09e-2)" "unprognostic (1.03e-1)" "unprognostic (3.07e-1)" 12.4 9.8 17.4 11.7 23.4 17.3 17.1 24.5 22.3 15.7 13.3 13.3 8.5 17.2 11.4 10.3 10.9 10.2 10.0 15.3 18.0 11.0 19.8 10.3 15.9 19.0 20.8 14.7 9.6 12.6 7.9 13.2 19.4 11.6 13.4 11.2 15.4 10.4 14.5 10.4 10.5 12.2 18.8 13.2 10.5 13.1 18.6 19.7 18.7 17.4 15.3 13.5 12.1 28.4 24.1 11.2 32.0 17.1 14.9 17.1 19.4 21.0 21.1 22.1 24.1 15.4 8.3 29.0 23.2 15.6 29.3 19.1 31.6 23.7 33.4 21.5 19.8 38.3 21.8 21.1 20.6 34.6 11.9 16.3 27.0 22.4 30.1 20.8 23.8 21.6 26.8 32.0 23.6 9.5 27.9 30.0 30.3 12.5 22.7 28.7 52.3 16.6 23.5 21.5 25.8 20.6 24.5 19.1 55.2 21.7 12.4 33.7 19.0 24.5 21.3 20.4 31.9 24.5 17.8 39.7 10.3 25.8 12.9 5.4 3.5 4.0 4.6 3.6 5.3 6.8 5.0 5.3 4.4 5.2 6.4 5.5 1.1 9.9 3.8 5.4 4.4 2.6 17.4 23.4 24.5 22.3 15.3 18.0 19.0 20.8 19.4 18.8 18.6 28.4 72.6 70.5 30.0 98.9 85.9 54.2 98.9 45.0 48.3 37.3 49.8 45.0 51.2 28.6 47.0 11.0 25.0 25.6 85.2 34.3 31.3 31.1 11.4 87.3 68.7 44.9 55.0 30.9 96.0 22.6 19.6 51.8 43.8 107.9 43.2 51.9 27.1 26.1 22.5 55.5 106.2 30.4 36.7 29.2 38.6 13.3 46.6 49.7 35.6 124.6 30.7 40.2 38.1 144.3 262.3 29.6 29.2 34.6 79.6 58.8 22.2 29.2 41.7 36.8 52.6 83.5 67.4 51.5 49.2 39.8 47.5 12.0 72.9 44.5 34.0 75.2 ZNF813 FLJ16542 ENSG00000198346 "Zinc finger protein 813" Q6ZN06 19 53467733-53496255 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RT4: 18.1" HPA056406 Uncertain Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA056406: AB_2683119" "unprognostic (1.20e-1)" "unprognostic (3.43e-2)" "unprognostic (1.17e-1)" "unprognostic (3.98e-3)" "unprognostic (2.28e-1)" "unprognostic (3.61e-3)" "unprognostic (1.48e-2)" "unprognostic (1.84e-3)" "unprognostic (3.39e-3)" "unprognostic (1.74e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-2)" "unprognostic (1.25e-3)" "unprognostic (8.18e-2)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (6.56e-2)" 1.2 1.1 0.9 1.5 1.3 1.4 2.2 1.1 1.1 1.1 1.4 1.8 1.8 1.3 3.9 1.2 1.8 1.4 0.7 1.0 1.2 1.3 0.7 1.4 2.2 1.4 1.4 1.8 1.3 2.4 0.6 3.6 1.3 4.9 1.7 0.6 1.2 1.1 0.4 2.0 1.7 1.0 1.0 1.9 1.9 1.6 1.3 2.2 1.9 0.5 2.1 1.4 1.2 1.8 0.9 0.8 2.6 4.3 2.2 2.6 6.0 2.4 2.4 1.6 2.3 4.6 2.7 6.9 2.3 2.3 3.0 1.4 6.3 2.7 3.0 0.0 9.9 6.9 1.8 5.2 1.1 0.0 7.1 2.2 2.2 1.8 1.3 0.9 1.4 4.9 3.8 0.1 2.6 1.3 9.2 3.8 3.3 0.8 2.4 5.6 5.7 3.4 1.5 18.1 1.1 2.5 0.0 4.5 1.6 5.6 1.8 3.4 2.3 0.9 3.1 0.1 2.3 3.6 5.5 7.5 0.0 0.0 4.7 1.8 1.1 0.8 1.7 1.6 1.7 1.6 1.6 1.9 1.2 2.4 3.0 2.3 0.5 3.6 3.0 1.1 1.3 1.4 0.9 1.3 1.1 1.1 1.0 1.2 1.4 1.4 1.3 1.0 1.3 1.8 3.4 6.4 1.8 0.3 4.4 1.8 3.1 1.4 4.6 0.7 1.9 1.8 1.9 5.7 2.6 0.0 0.0 5.0 4.3 2.5 1.9 2.2 1.7 2.6 3.2 4.0 0.0 3.4 0.3 1.2 10.1 4.1 3.6 2.6 0.0 7.0 13.6 1.2 2.8 3.3 1.0 3.2 2.0 3.0 1.7 0.9 2.5 2.6 3.6 1.0 3.7 1.1 3.1 2.0 2.8 1.5 3.4 2.2 1.5 5.0 1.2 0.8 2.0 0.6 0.0 4.0 3.4 0.9 4.1 2.2 1.6 8.9 2.8 2.6 3.9 2.3 ZPR1 ZNF259 ENSG00000109917 "ZPR1 zinc finger" O75312 11 116773799-116788039 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 228.5;Late spermatids: 418.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022596, HPA030979" Uncertain Approved Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB022596: , HPA030979: AB_2673684" "unprognostic (2.12e-2)" "unprognostic (3.55e-1)" "unprognostic (6.22e-2)" "unprognostic (1.44e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (8.01e-4)" "prognostic unfavorable (5.87e-6)" "unprognostic (1.04e-1)" "unprognostic (1.09e-1)" "unprognostic (9.42e-2)" "unprognostic (4.96e-3)" "unprognostic (4.79e-2)" "unprognostic (2.17e-2)" "unprognostic (1.48e-1)" "unprognostic (1.73e-1)" "unprognostic (1.71e-2)" "unprognostic (6.66e-2)" 21.2 12.3 12.2 14.3 12.7 35.2 16.5 10.9 13.4 13.4 8.3 13.9 10.6 14.0 13.0 16.5 13.5 11.6 14.3 13.7 13.6 16.3 24.5 14.4 15.6 12.4 12.2 15.2 21.1 9.6 11.8 12.8 12.6 13.3 12.6 5.6 12.3 12.3 28.4 15.3 14.2 15.6 13.6 14.1 16.1 27.3 14.0 13.9 14.1 14.3 18.7 20.3 13.6 14.2 23.3 33.3 19.4 36.9 29.0 30.1 25.7 39.0 30.6 34.4 36.6 84.0 41.1 53.2 67.4 39.1 61.9 31.0 53.9 35.7 48.5 34.7 26.5 112.6 18.1 45.6 57.4 51.4 45.2 28.7 49.3 65.6 105.6 23.0 38.7 33.8 54.4 35.3 50.7 28.9 42.3 64.0 35.5 63.9 49.7 32.9 29.6 58.9 33.1 40.0 25.3 43.7 32.0 42.2 28.1 33.1 28.5 34.9 33.3 44.3 22.0 26.2 55.6 24.6 19.8 64.3 24.2 89.9 43.5 12.7 20.7 16.5 15.9 22.2 18.5 28.1 21.6 20.5 22.5 22.6 21.2 19.3 3.0 24.5 18.5 16.2 23.7 20.3 12.2 12.7 10.9 13.4 13.7 13.6 12.4 12.2 12.6 13.6 14.0 14.2 23.8 9.6 15.9 0.7 37.0 0.0 66.3 0.0 32.5 8.8 21.6 20.1 11.7 20.0 9.9 20.2 0.0 34.5 36.3 13.6 45.0 45.8 228.5 18.9 20.1 22.0 23.4 14.7 1.1 40.2 58.0 21.3 18.8 24.2 28.0 29.9 13.9 19.9 36.3 5.0 1.4 19.2 0.0 19.5 0.0 418.8 19.0 25.1 0.0 1.9 36.6 7.9 26.8 1.0 2.4 62.5 20.3 12.4 29.4 83.1 42.5 28.8 2.9 6.2 6.6 29.3 23.3 75.2 33.2 30.4 0.0 45.8 34.3 27.1 25.4 84.2