Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCA2 ABC2 ENSG00000107331 "ATP binding cassette subfamily A member 2" Q9BZC7 9 137007234-137028922 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "brain: 543.0" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 388.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 66.4" "Low region specificity" "Detected in all" HPA042886 Approved Supported Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA042886: AB_2678213" "unprognostic (1.01e-2)" "unprognostic (9.21e-3)" "unprognostic (9.59e-2)" "unprognostic (6.15e-2)" "unprognostic (1.02e-1)" "unprognostic (8.08e-2)" "unprognostic (2.20e-2)" "unprognostic (1.13e-2)" "unprognostic (5.61e-3)" "unprognostic (1.76e-1)" "unprognostic (2.93e-2)" "unprognostic (2.74e-2)" "unprognostic (6.78e-3)" "unprognostic (3.14e-3)" "unprognostic (1.37e-1)" "unprognostic (2.80e-1)" "unprognostic (1.36e-1)" 9.0 6.0 90.2 4.2 269.7 6.7 6.3 194.3 189.0 5.9 0.0 7.9 3.0 4.3 4.5 3.3 6.2 5.9 9.1 92.4 101.3 7.1 7.4 6.2 4.6 284.9 211.4 3.2 9.3 13.4 23.4 3.1 255.1 7.1 2.2 2.7 8.4 4.7 7.3 6.6 6.5 2.4 135.7 9.5 11.6 2.9 204.9 2.9 15.2 3.5 1.8 5.6 5.3 543.0 8.6 9.2 4.5 18.2 11.1 11.8 7.9 9.5 3.8 4.2 1.5 2.8 10.3 0.4 26.2 10.2 4.1 14.4 2.9 6.9 0.8 6.4 5.9 0.8 26.2 3.5 5.5 13.3 14.5 5.0 6.3 3.0 0.9 15.3 2.4 2.7 2.2 1.5 5.3 25.7 0.1 29.1 2.4 10.9 9.5 13.3 4.6 13.0 2.9 2.0 17.4 20.0 10.1 19.6 7.2 0.3 66.4 17.4 11.9 11.2 6.1 16.0 3.9 0.3 0.2 0.1 19.0 2.6 5.8 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.6 0.2 0.3 90.2 269.7 194.3 189.0 92.4 101.3 284.9 211.4 255.1 135.7 204.9 543.0 7.2 0.0 0.0 26.1 2.3 3.3 1.5 7.1 3.4 12.6 6.2 9.1 5.1 17.2 2.3 1.8 14.6 1.0 24.0 15.2 1.9 2.9 1.0 6.7 4.8 4.7 34.7 6.6 23.4 1.5 1.2 6.4 5.1 6.9 0.0 12.6 6.1 8.6 1.2 37.0 20.8 7.0 2.0 3.5 4.6 1.6 22.1 2.7 5.4 4.7 0.9 12.8 24.7 12.5 388.7 2.3 7.1 23.7 6.7 2.4 11.6 1.4 4.9 7.9 0.0 11.4 4.7 0.5 4.7 1.7 2.7 0.8 13.2 2.8 11.0 1.3 ABCB9 EST122234 ENSG00000150967 "ATP binding cassette subfamily B member 9" Q9NP78 12 122920951-122981649 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peptide transport, Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.4;testis: 17.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 46.3;Inhibitory neurons: 41.7;Plasma cells: 92.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6;memory B-cell: 2.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "GAMG: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033052, HPA035113, HPA035114" Approved Supported Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB033052: AB_2273463, HPA035113: AB_2674470, HPA035114: AB_10601329" "unprognostic (1.47e-2)" "unprognostic (6.46e-4)" "unprognostic (3.96e-2)" "unprognostic (2.73e-1)" "prognostic unfavorable (5.65e-4)" "unprognostic (1.46e-1)" "unprognostic (2.67e-2)" "unprognostic (2.35e-1)" "unprognostic (4.08e-2)" "unprognostic (6.07e-2)" "unprognostic (2.28e-1)" "unprognostic (1.24e-1)" "unprognostic (1.37e-2)" "unprognostic (6.97e-2)" "unprognostic (1.70e-1)" "unprognostic (3.58e-3)" "unprognostic (2.71e-2)" 3.0 3.1 11.9 1.6 10.4 3.4 3.9 19.7 20.4 3.1 0.0 2.4 2.7 3.0 4.9 2.9 2.9 2.5 4.9 8.2 7.5 3.6 1.2 1.6 1.6 7.3 9.1 4.0 3.2 2.8 11.6 1.8 6.0 3.5 2.1 7.3 5.6 2.8 1.6 3.3 3.4 2.0 2.1 3.6 3.4 17.8 16.0 1.3 3.0 1.2 1.9 1.9 3.1 10.6 4.7 8.6 4.7 4.5 2.0 3.8 2.2 3.0 4.3 5.1 3.2 3.7 5.3 5.2 3.4 2.8 25.9 4.3 3.5 7.2 2.0 1.0 7.0 22.9 7.7 5.9 2.2 1.1 9.0 5.3 2.8 7.5 2.3 12.5 5.7 5.1 4.6 3.8 2.9 10.6 1.7 2.2 1.5 5.0 8.4 6.4 1.3 5.0 2.6 3.1 5.0 1.5 1.5 10.7 10.7 1.8 12.6 1.6 2.5 3.6 12.2 11.5 8.8 12.3 7.4 1.5 6.3 2.5 20.2 2.6 0.3 0.3 0.3 0.1 0.8 2.5 0.3 0.3 0.2 0.5 0.6 0.6 0.7 0.2 0.1 0.1 0.2 0.8 11.9 10.4 19.7 20.4 8.2 7.5 7.3 9.1 6.0 2.1 16.0 10.6 9.7 6.4 4.6 13.4 15.9 3.2 2.8 1.5 8.6 10.7 3.9 5.0 2.0 0.0 2.5 3.7 14.6 5.2 3.4 1.9 0.0 3.8 8.9 2.6 2.6 4.0 1.2 2.1 46.3 1.5 1.8 2.0 4.1 5.6 2.5 3.0 2.9 1.2 1.1 6.7 41.7 1.1 0.0 1.0 2.1 23.2 2.8 1.8 5.4 7.5 0.3 20.0 2.1 4.0 18.1 2.5 0.1 2.6 92.2 2.1 4.1 0.9 0.7 5.3 6.6 2.1 3.7 9.6 3.5 3.3 3.1 1.4 3.9 2.9 2.6 1.8 ABCG1 ABC8 ENSG00000160179 "ATP binding cassette subfamily G member 1" P45844 21 42199689-42297244 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 122.6;Syncytiotrophoblasts: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 35.5;neutrophil: 36.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.6" "Cell line enhanced" "Detected in many" "hTCEpi: 25.5;JURKAT: 38.4;MCF7: 33.2;MOLT-4: 31.5;OE19: 54.9;RPMI-8226: 25.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031470, HPA031471" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "HPA031470: AB_10599188, HPA031471: AB_10600201" "unprognostic (2.89e-2)" "unprognostic (2.53e-2)" "unprognostic (9.96e-2)" "unprognostic (4.20e-3)" "unprognostic (2.87e-1)" "unprognostic (3.09e-2)" "unprognostic (5.74e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.66e-3)" "unprognostic (3.66e-3)" "unprognostic (6.37e-2)" "prognostic favorable (7.16e-6)" "unprognostic (1.40e-2)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (2.42e-2)" 17.2 37.7 18.3 12.1 25.5 8.1 15.2 14.4 20.2 8.1 20.0 14.1 17.5 4.9 3.9 4.1 6.3 13.8 10.5 15.5 17.0 10.2 6.3 29.4 18.1 12.0 19.9 6.3 5.3 24.4 10.7 13.7 13.3 6.2 15.0 29.1 16.1 7.0 19.6 16.8 22.0 4.0 12.2 31.2 15.9 1.1 20.3 18.9 8.5 6.2 12.1 12.9 5.0 24.7 0.0 6.0 4.6 2.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 3.1 1.9 0.8 0.0 0.7 0.9 0.0 8.8 0.0 8.5 0.5 10.2 19.2 0.0 17.4 0.0 0.4 2.0 25.5 0.1 3.9 0.0 18.2 38.4 0.0 0.1 0.0 33.2 31.5 0.2 1.4 54.9 10.3 0.4 0.0 25.8 0.0 2.8 22.3 5.8 3.7 13.5 0.0 0.4 5.7 0.9 11.8 0.0 4.7 0.1 0.0 13.1 4.2 0.0 0.1 3.3 0.5 1.7 1.7 35.5 3.0 0.5 5.6 5.5 6.1 6.0 1.1 7.0 5.8 5.0 36.6 7.4 0.3 2.5 7.4 2.1 18.3 25.5 14.4 20.2 15.5 17.0 12.0 19.9 13.3 12.2 20.3 24.7 38.2 6.4 8.2 0.3 21.3 8.9 6.9 3.2 5.7 48.4 4.1 6.9 9.5 4.3 5.9 25.8 50.1 7.0 7.0 33.4 3.9 2.6 4.5 21.6 6.3 33.8 3.5 5.7 13.2 1.2 1.8 7.5 11.2 45.3 0.0 1.2 42.8 0.6 16.0 11.8 17.8 12.1 8.2 44.5 23.4 7.6 0.3 20.9 3.6 7.5 4.3 16.1 3.1 43.2 40.6 2.3 8.3 1.9 4.0 3.0 36.6 1.1 4.5 122.6 6.6 1.6 3.5 0.6 0.5 1.0 6.7 63.1 21.4 10.4 1.1 9.1 ACKR2 "CCBP2, CCR10, CCR9, CMKBR9, D6" ENSG00000144648 "Atypical chemokine receptor 2" O00590 3 42804752-42887974 "G-protein coupled receptors, Predicted membrane proteins" "Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 9.4;placenta: 16.0" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 33.0;Extravillous trophoblasts: 106.2;Syncytiotrophoblasts: 73.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 3.9;NK-cell: 1.1" "Group enriched" "Detected in many" 7 "granulocytes: 3.9;NK-cells: 1.1" "Cell line enhanced" "Detected in some" "BEWO: 51.2;HEL: 17.1;SK-BR-3: 28.0;U-937: 10.7" "Group enriched" "Detected in many" 5 "amygdala: 2.2;basal ganglia: 7.9;cerebral cortex: 4.9;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "HPA013819, HPA073493" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Vesicles, Cytosol" Nucleoplasm "HPA013819: AB_1846126, HPA073493: AB_2686610" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.90e-2)" "unprognostic (8.15e-2)" "unprognostic (7.51e-2)" "unprognostic (1.54e-2)" "unprognostic (1.21e-3)" "unprognostic (1.74e-1)" "unprognostic (2.99e-1)" "unprognostic (6.20e-2)" "unprognostic (8.47e-2)" "unprognostic (8.45e-2)" "unprognostic (1.13e-4)" "unprognostic (5.13e-3)" "unprognostic (3.22e-1)" "unprognostic (5.58e-3)" "unprognostic (6.09e-2)" 6.7 1.0 1.5 1.0 1.0 0.7 2.8 1.5 1.3 1.7 0.9 1.9 0.9 0.9 2.8 1.6 2.3 1.3 1.3 1.0 0.5 1.5 9.4 1.6 1.1 1.4 1.4 0.4 0.9 0.4 0.5 16.0 1.3 0.6 2.1 0.7 2.2 0.4 0.6 2.6 1.1 1.1 0.6 0.7 1.1 0.8 1.1 0.4 2.9 0.9 2.1 1.8 2.3 1.3 0.1 0.0 0.2 0.4 2.4 0.2 51.2 0.1 0.0 0.0 0.0 0.5 0.1 1.2 0.1 0.1 0.2 0.4 0.0 0.2 0.1 0.1 0.2 17.1 0.4 3.1 0.1 0.2 1.9 0.5 0.5 0.0 0.1 0.0 0.1 0.5 2.2 0.4 0.3 0.3 0.0 0.2 0.1 0.7 0.2 0.1 0.0 0.1 0.7 7.5 0.3 0.1 1.3 28.0 0.1 2.9 2.8 0.3 0.1 0.1 0.1 0.2 0.1 0.6 0.1 0.1 0.1 10.7 0.1 0.4 0.1 3.9 0.2 0.2 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.1 0.4 1.1 0.3 0.1 0.0 0.1 1.5 1.0 1.5 1.3 1.0 0.5 1.4 1.4 1.3 0.6 1.1 1.3 1.0 0.0 0.0 9.8 0.1 0.1 0.1 0.3 0.0 0.7 1.2 0.3 0.8 1.5 3.3 0.0 2.1 33.0 0.3 3.0 1.9 0.1 3.0 3.7 0.8 3.3 1.8 0.0 2.0 0.0 106.2 2.1 0.0 5.9 2.5 2.5 4.6 7.0 5.3 1.7 1.2 0.6 0.0 0.6 0.4 1.8 0.3 0.4 0.0 5.6 0.1 2.6 0.0 1.0 4.5 0.8 0.5 1.2 0.1 0.4 1.6 0.5 3.4 1.0 0.0 0.4 0.3 4.8 5.4 0.0 0.0 73.6 0.5 0.5 1.1 0.6 ACKR4 "CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1" ENSG00000129048 "Atypical chemokine receptor 4" Q9NPB9 3 132597270-132618967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Fibroblasts: 21.4;Proximal enterocytes: 19.1;Respiratory ciliated cells: 15.7" "Cancer enhanced" "Detected in many" "stomach cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "BJ hTERT+: 285.1" "Group enriched" "Detected in some" 7 "cerebellum: 4.7;pons and medulla: 1.5" "Low region specificity" "Detected in all" HPA054926 Approved Vesicles,Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Mitochondria" "HPA054926: " "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.62e-2)" "unprognostic (8.27e-2)" "unprognostic (5.17e-2)" "unprognostic (4.55e-3)" "unprognostic (8.93e-2)" "unprognostic (2.26e-1)" "unprognostic (4.85e-2)" "unprognostic (4.20e-3)" "unprognostic (1.03e-3)" "unprognostic (2.69e-3)" "unprognostic (1.95e-1)" "unprognostic (2.01e-1)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (1.22e-1)" 11.1 1.4 0.6 1.0 0.2 0.8 5.5 0.3 0.3 0.7 0.9 1.9 15.8 3.7 1.7 1.4 2.0 6.5 5.7 0.4 0.0 1.1 1.0 8.0 2.1 0.3 0.5 1.0 2.6 0.0 6.7 0.2 0.3 0.5 1.3 0.6 7.1 1.9 0.5 8.9 13.0 2.2 0.3 1.6 10.2 0.4 0.1 0.5 1.4 1.0 1.6 4.6 1.1 0.2 0.2 0.0 0.2 0.2 19.9 10.7 0.1 47.7 285.1 2.8 7.9 0.2 0.4 3.3 0.0 29.9 0.2 0.1 0.0 0.0 1.8 1.1 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.0 1.3 0.0 0.0 4.9 0.1 0.2 0.6 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 1.0 0.1 0.1 0.2 0.0 0.5 0.1 0.7 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.3 0.3 0.4 0.0 0.3 0.5 0.3 0.3 0.1 0.2 1.6 38.5 1.1 0.7 0.1 6.5 0.6 1.3 0.0 1.6 0.3 0.3 0.7 1.5 2.3 5.5 6.2 0.2 0.1 1.1 0.0 0.2 2.9 2.9 0.6 3.9 0.0 0.0 0.6 12.1 0.1 21.4 10.7 0.6 0.0 0.7 9.7 0.2 0.4 1.7 0.5 0.8 0.0 0.3 5.1 0.4 2.1 0.3 1.8 1.9 6.8 0.9 0.0 0.0 0.3 5.1 0.1 2.6 0.5 0.4 19.1 3.0 15.7 3.4 0.0 1.3 2.6 0.1 0.1 0.6 6.5 0.3 0.5 12.5 3.7 1.2 ACOT8 "hACTE-III, hTE, NAP1, PTE-2, PTE1" ENSG00000101473 "Acyl-CoA thioesterase 8" O14734 20 45841721-45857405 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Host-virus interaction, Lipid metabolism, Peroxisome biogenesis" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 104.2;Late spermatids: 90.3;Proximal enterocytes: 105.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010261 Approved Supported Vesicles,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Mitochondria "CAB010261: AB_2221664" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (4.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.92e-2)" "unprognostic (4.70e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" "unprognostic (2.03e-2)" "prognostic favorable (3.18e-4)" "unprognostic (2.79e-1)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (2.98e-1)" 8.3 31.7 27.8 8.6 29.8 18.1 7.6 28.2 35.2 9.3 24.3 18.5 21.1 8.5 11.0 17.5 10.7 9.2 28.1 29.8 28.6 21.3 26.0 11.0 12.6 27.0 28.5 8.0 15.6 15.1 15.4 7.1 28.7 12.7 12.8 9.2 12.8 5.9 28.7 17.0 20.5 6.4 26.0 12.3 21.3 20.2 28.7 13.1 11.4 17.8 9.7 11.0 10.4 28.1 16.8 20.2 6.8 13.4 18.3 11.0 11.7 11.1 9.5 15.1 13.7 29.2 22.7 20.8 48.2 16.3 35.4 32.3 13.0 27.8 6.6 15.5 22.3 21.2 25.1 28.5 16.9 19.9 19.3 12.9 21.3 15.1 10.9 22.6 9.4 23.6 18.8 24.2 11.0 47.4 28.7 27.0 11.8 32.4 52.2 14.0 12.2 37.6 16.5 19.1 23.1 10.8 24.9 61.7 39.5 10.6 34.4 48.8 11.6 37.9 8.5 19.5 18.9 20.7 33.8 14.0 46.3 21.2 20.8 34.3 34.3 43.6 24.8 34.6 21.8 27.5 23.2 21.9 36.7 27.9 20.0 21.6 25.0 16.3 34.2 23.3 31.9 26.7 27.8 29.8 28.2 35.2 29.8 28.6 27.0 28.5 28.7 26.0 28.7 28.1 8.2 35.3 14.1 5.9 17.9 6.1 12.3 21.9 8.6 19.2 9.8 10.9 9.3 11.5 17.7 12.9 16.7 34.2 11.8 104.2 64.6 21.6 38.5 14.2 10.4 10.9 19.2 17.0 12.3 21.0 20.9 11.4 19.9 14.0 14.0 27.6 11.4 25.5 27.8 8.4 12.0 37.3 10.2 18.6 7.1 90.3 9.9 17.5 10.6 3.7 27.5 17.8 34.0 5.0 9.6 21.6 68.4 8.6 21.3 11.3 105.4 81.5 27.1 22.8 13.1 5.8 12.8 27.0 10.2 16.1 8.0 19.4 13.9 37.6 30.3 16.0 ACOX2 "BRCACOX, BRCOX, THCCox" ENSG00000168306 "Acyl-CoA oxidase 2" Q99424 3 58505136-58537283 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 177.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 89.0;Proximal enterocytes: 27.9;Proximal tubular cells: 51.0" "Cancer enhanced" "Detected in many" "liver cancer: 25.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.4;ASC TERT1: 25.9;fHDF/TERT166: 9.2;Hep G2: 10.8;HSkMC: 17.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA038280, HPA064845" Enhanced Approved Vesicles,Cytosol No No 29000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Vesicles Cytosol "HPA038280: AB_10672623, HPA064845: AB_2685368" "unprognostic (6.62e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-1)" "unprognostic (2.51e-2)" "unprognostic (8.34e-2)" "unprognostic (1.48e-2)" "unprognostic (8.67e-3)" "unprognostic (6.45e-2)" "unprognostic (1.00e-1)" "unprognostic (1.85e-1)" "unprognostic (1.70e-3)" "unprognostic (1.26e-2)" "unprognostic (1.68e-3)" "unprognostic (4.00e-3)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (5.63e-3)" 8.8 8.3 4.1 2.1 4.6 0.1 5.8 4.4 4.5 9.3 16.8 12.9 25.4 9.4 5.8 6.3 10.8 8.2 16.7 4.3 4.5 42.1 177.3 6.2 1.7 5.3 4.8 11.2 4.6 9.6 4.6 3.4 4.4 10.8 8.3 1.8 7.2 9.8 8.2 2.9 21.6 11.2 4.5 1.4 4.0 4.9 4.9 4.0 16.1 17.0 1.2 8.7 6.0 4.1 0.0 0.0 0.2 0.0 16.4 25.9 4.7 3.1 0.2 0.0 0.4 0.8 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 2.3 0.0 0.0 17.4 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.6 4.4 4.5 4.3 4.5 5.3 4.8 4.4 4.5 4.9 4.1 1.9 3.2 5.8 11.1 0.6 0.6 7.6 0.5 5.7 0.3 1.3 3.8 14.3 4.3 0.9 3.7 0.0 0.7 0.0 4.2 15.6 0.3 0.1 0.4 1.3 1.6 3.0 2.7 0.6 1.9 0.4 8.6 2.0 0.2 1.3 8.6 6.1 89.0 5.2 1.7 0.6 5.1 0.0 1.9 0.4 1.8 10.8 1.7 0.0 1.0 0.5 10.8 0.0 0.5 0.0 0.4 0.8 8.6 0.1 0.6 27.9 51.0 0.0 0.8 6.6 7.0 5.2 0.4 0.4 3.0 0.3 0.8 0.3 9.6 4.6 3.8 ADAM10 "CD156C, HsT18717, kuz, MADM" ENSG00000137845 "ADAM metallopeptidase domain 10" O14672 15 58588809-58749791 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 377.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 296.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001709, HPA050670" Approved Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 690000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "CAB001709: , HPA050670: " "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (5.04e-2)" "unprognostic (3.09e-1)" "unprognostic (2.70e-3)" "unprognostic (7.48e-2)" "prognostic unfavorable (8.46e-5)" "unprognostic (3.99e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (6.69e-2)" "unprognostic (2.57e-2)" "unprognostic (2.57e-3)" "unprognostic (9.14e-2)" "unprognostic (2.09e-2)" "unprognostic (1.60e-2)" 14.9 8.7 11.4 19.0 18.6 18.7 15.2 20.2 15.0 16.0 9.7 22.2 15.9 16.3 7.7 15.4 13.9 18.9 12.1 12.2 12.7 18.0 16.1 21.0 22.2 18.2 17.6 14.1 8.8 7.9 8.2 29.0 17.5 25.2 17.2 10.8 9.3 12.2 6.1 16.9 17.5 13.3 13.7 29.0 20.3 8.5 15.5 42.7 28.6 7.1 16.4 28.0 10.4 25.2 48.4 88.5 27.6 31.2 34.8 49.8 70.0 39.0 116.0 28.6 39.1 39.9 62.6 22.7 118.0 35.2 49.2 95.9 16.8 43.5 37.0 30.1 19.3 38.7 35.1 42.1 40.8 25.0 103.8 44.4 30.0 19.9 29.2 41.1 55.6 45.0 24.5 57.9 50.4 15.4 89.5 32.0 40.2 15.4 14.6 36.4 91.6 57.1 66.6 121.4 29.9 20.3 44.0 52.8 73.1 60.0 30.4 55.0 41.4 37.1 41.2 296.6 39.6 30.7 70.7 23.5 54.1 50.8 67.3 30.9 36.2 19.2 12.8 41.1 19.2 8.3 12.7 11.6 23.6 9.6 12.7 10.8 51.5 17.7 48.6 10.2 18.2 25.8 11.4 18.6 20.2 15.0 12.2 12.7 18.2 17.6 17.5 13.7 15.5 25.2 60.1 83.3 50.8 83.2 37.9 26.6 30.7 33.3 33.0 22.7 61.6 30.9 40.0 30.0 46.7 80.9 27.1 35.6 69.4 79.0 1.9 56.0 21.2 39.5 56.4 72.5 36.1 20.8 106.1 31.8 57.8 36.1 53.0 74.0 30.3 31.5 71.4 36.2 63.8 45.4 96.2 43.6 36.7 90.1 28.9 19.4 18.0 77.9 46.2 147.1 69.0 30.6 44.3 75.9 377.6 48.9 48.1 17.0 51.0 89.1 45.1 23.7 41.2 33.4 13.1 34.4 42.8 20.3 17.8 39.5 22.3 26.5 51.3 34.1 39.5 83.9 ADAMTS7 "ADAM-TS7, DKFZp434H204" ENSG00000136378 "ADAM metallopeptidase with thrombospondin type 1 motif 7" Q9UKP4 15 78759206-78811464 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 30.6" "Cell type enriched" "Detected in some" 4 "Theca cells: 44.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "HMC-1: 259.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA045284, HPA048453" Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA045284: AB_2679285, HPA048453: AB_2680399" "unprognostic (5.94e-3)" "unprognostic (9.94e-3)" "unprognostic (2.76e-2)" "unprognostic (7.09e-2)" "unprognostic (3.38e-1)" "unprognostic (1.93e-1)" "unprognostic (5.88e-4)" "unprognostic (3.34e-3)" "unprognostic (2.89e-2)" "unprognostic (3.31e-2)" "unprognostic (1.83e-2)" "unprognostic (3.79e-1)" "unprognostic (1.34e-2)" "prognostic unfavorable (9.53e-4)" "unprognostic (1.59e-1)" "unprognostic (2.66e-2)" "unprognostic (8.86e-2)" 6.6 5.3 0.5 1.8 0.4 0.1 3.8 0.3 0.5 6.0 0.6 4.2 1.1 7.2 0.1 0.9 2.2 2.3 30.6 0.4 0.5 2.2 1.1 6.3 0.9 0.5 0.5 6.1 0.5 0.4 0.8 2.1 0.4 1.8 0.2 0.5 1.3 0.4 1.1 1.8 2.6 1.4 0.2 5.2 2.2 4.1 0.7 0.1 2.1 0.5 0.2 3.0 2.5 0.6 0.0 1.1 16.5 7.5 6.9 8.2 20.9 3.7 1.3 1.0 0.6 0.0 0.1 0.0 4.8 0.4 1.0 0.4 0.4 2.0 0.0 0.3 0.6 2.1 0.5 0.1 6.9 0.0 259.9 3.3 2.0 1.9 1.0 5.3 24.0 0.0 0.3 0.7 5.6 0.0 0.1 4.9 4.7 0.0 1.4 17.3 7.7 0.3 0.5 0.9 0.3 23.9 4.8 0.0 0.6 4.0 3.2 0.4 29.8 9.4 1.0 3.3 0.0 0.1 0.0 0.0 1.6 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.3 0.5 0.4 0.5 0.5 0.5 0.4 0.2 0.7 0.6 7.5 0.0 0.0 3.6 0.3 0.4 0.2 0.7 0.0 0.3 0.1 0.5 9.8 0.0 0.3 0.0 0.0 0.3 0.2 0.1 0.0 0.1 4.9 0.8 7.5 10.5 0.0 0.0 0.1 0.0 0.3 10.1 0.5 0.9 3.8 7.2 2.9 0.3 0.7 0.0 0.2 0.0 2.0 0.0 0.8 2.7 1.5 0.1 1.8 1.0 0.1 1.3 0.0 9.5 1.4 0.3 0.0 1.9 0.0 0.3 0.0 0.1 0.3 0.1 0.0 3.7 5.0 2.6 2.0 0.2 0.1 0.3 0.5 44.9 0.1 0.3 ADRA2B "ADRA2L1, ADRA2RL1, ADRARL1" ENSG00000274286 "Adrenoceptor alpha 2B" P18089 2 96112876-96116571 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 9.0;Langerhans cells: 8.0;Sertoli cells: 32.9;Smooth muscle cells: 13.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.5;EFO-21: 1.0" "Group enriched" "Detected in some" 6 "basal ganglia: 2.5;cerebellum: 1.0;thalamus: 3.2" "Low region specificity" "Detected in some" "HPA066029, HPA074948" Approved Supported Vesicles,Cytosol NA NA "Cluster 18: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles Cytosol "HPA066029: AB_2685599, HPA074948: " "unprognostic (6.16e-2)" "unprognostic (1.31e-2)" "unprognostic (1.76e-2)" "unprognostic (4.93e-4)" "unprognostic (1.84e-2)" "unprognostic (5.24e-2)" "unprognostic (6.80e-5)" "unprognostic (4.85e-2)" "unprognostic (1.69e-1)" "unprognostic (3.16e-2)" "unprognostic (8.34e-2)" "unprognostic (2.54e-1)" "unprognostic (2.21e-1)" "unprognostic (4.43e-2)" "unprognostic (3.39e-1)" "unprognostic (1.36e-1)" "unprognostic (6.55e-2)" 6.4 2.1 1.5 0.3 1.7 0.8 3.0 1.4 2.7 1.5 4.9 2.3 0.3 1.9 3.8 0.7 3.0 0.6 10.1 1.2 1.4 5.1 7.0 0.5 0.2 1.8 1.6 1.7 0.8 0.5 0.5 0.8 1.7 1.4 0.3 0.0 2.2 1.5 6.4 1.9 2.6 0.7 1.3 8.6 2.2 1.6 2.6 0.2 1.3 5.0 0.1 2.5 1.8 2.4 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.7 1.4 2.7 1.2 1.4 1.8 1.6 1.7 1.3 2.6 2.4 2.9 0.0 0.0 0.0 0.9 1.1 0.7 0.7 0.6 0.0 0.9 0.9 2.5 0.0 1.5 1.8 0.0 0.8 2.9 0.1 0.0 0.2 0.0 2.2 1.0 2.4 2.4 0.0 0.0 0.6 0.2 1.0 1.1 9.0 0.0 0.0 2.5 0.0 0.3 0.0 0.0 0.2 0.0 0.3 8.0 0.0 1.8 5.1 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.4 0.7 0.0 0.1 1.4 0.0 32.9 0.7 13.3 0.0 0.3 0.6 1.4 0.4 2.8 0.1 0.1 0.3 AEBP1 ACLP ENSG00000106624 "AE binding protein 1" Q8IUX7 7 44104345-44114562 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Calmodulin-binding, DNA-binding, Repressor" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 103.0;Fibroblasts: 263.2;Leydig cells: 151.6;Peritubular cells: 508.9;Smooth muscle cells: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.6" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.6" "Cell line enhanced" "Detected in many" "ASC diff: 141.1;BJ: 193.0;BJ hTERT+: 126.0;fHDF/TERT166: 208.9;JURKAT: 145.0;WM-115: 117.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 57.6" "CAB009966, HPA047724, HPA063595, HPA064970" Supported Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2700000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB009966: AB_2225690, HPA047724: AB_2680132, HPA063595: AB_2685052, HPA064970: AB_2685394" "unprognostic (1.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.66e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.13e-1)" "unprognostic (7.00e-2)" "unprognostic (8.79e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "unprognostic (1.26e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (9.31e-9)" "unprognostic (2.88e-3)" "unprognostic (9.58e-2)" "unprognostic (1.17e-2)" "unprognostic (6.28e-3)" 190.5 59.9 45.0 59.8 56.0 10.6 153.0 38.6 44.8 312.1 28.0 95.3 19.2 268.8 59.6 65.7 199.8 155.9 156.7 47.3 92.9 68.7 20.3 166.0 45.5 114.7 81.5 253.7 28.9 10.1 43.3 89.0 79.6 112.1 25.0 1.3 50.7 213.5 21.3 84.8 79.1 119.3 74.3 54.4 71.2 40.4 52.1 73.3 83.7 14.1 16.7 138.7 198.0 66.6 0.6 0.0 44.5 0.1 141.1 49.6 1.0 193.0 126.0 21.6 4.5 0.0 0.1 5.3 20.9 208.9 0.2 0.1 2.4 3.5 9.1 0.6 0.0 13.3 0.1 0.0 39.6 0.1 0.3 75.8 0.0 72.9 0.1 1.1 9.7 145.0 8.3 0.3 0.0 0.2 86.9 16.1 19.1 0.0 0.4 71.3 1.7 1.7 5.0 0.0 4.9 25.3 0.1 0.3 85.9 41.9 0.4 14.4 34.1 0.0 86.2 0.5 0.3 1.0 0.9 102.8 0.4 0.2 117.9 0.0 0.0 0.0 0.3 0.0 0.2 1.5 0.2 0.0 0.0 1.4 0.9 0.5 0.0 0.1 0.0 7.6 0.0 0.3 45.0 56.0 38.6 44.8 47.3 92.9 114.7 81.5 79.6 74.3 52.1 66.6 23.6 0.0 2.5 32.3 11.8 34.5 5.7 1.3 1.8 0.8 2.0 14.6 26.4 1.5 1.4 7.3 0.0 2.0 22.7 0.0 0.0 0.9 3.1 3.3 103.0 18.0 0.0 1.3 0.1 0.0 3.3 263.2 8.6 2.9 2.5 33.3 30.4 0.6 3.6 0.0 0.3 0.0 0.0 1.8 42.0 18.0 151.6 3.2 85.4 17.8 1.0 0.2 1.0 6.0 0.3 0.4 0.0 508.9 9.7 16.9 0.0 2.2 2.2 0.8 39.5 23.6 173.4 4.0 4.6 1.5 27.4 3.4 4.8 28.7 0.0 2.4 AFTPH "FLJ20080, FLJ23793, MGC33965, Nbla10388" ENSG00000119844 Aftiphilin Q6ULP2 2 64524305-64593005 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034990, HPA034991" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Cytosol "Golgi apparatus, Vesicles" "HPA034990: AB_2674398, HPA034991: AB_10603577" "unprognostic (7.30e-2)" "unprognostic (4.72e-2)" "unprognostic (9.16e-2)" "unprognostic (8.54e-2)" "unprognostic (3.24e-1)" "unprognostic (4.25e-2)" "unprognostic (2.54e-2)" "unprognostic (1.75e-2)" "unprognostic (1.52e-1)" "unprognostic (8.44e-2)" "unprognostic (3.42e-2)" "unprognostic (4.65e-2)" "prognostic favorable (2.37e-5)" "prognostic favorable (8.44e-4)" "unprognostic (3.12e-1)" "unprognostic (1.74e-1)" "prognostic favorable (1.83e-4)" 15.9 20.2 24.6 21.1 24.9 21.3 32.4 31.2 38.4 22.5 28.3 30.5 23.1 18.8 43.7 29.6 22.9 21.9 12.0 25.3 25.6 56.1 33.6 21.9 37.2 24.6 24.6 19.3 31.6 38.0 25.1 15.0 24.5 34.5 33.7 36.8 28.9 18.6 15.4 33.2 24.5 17.3 24.8 26.4 33.7 24.6 25.4 29.3 25.3 12.9 41.4 25.5 22.4 26.2 29.8 19.3 14.1 17.1 17.8 15.1 23.4 16.7 24.9 26.9 20.1 22.4 21.9 43.9 16.0 20.7 31.1 23.5 24.6 23.3 34.8 42.8 13.5 21.0 12.0 26.5 18.8 40.5 34.5 7.5 48.6 17.4 39.6 19.8 21.4 21.8 16.0 38.7 16.8 16.9 21.9 49.1 13.0 55.9 14.3 17.7 22.6 28.8 48.9 31.5 25.9 13.1 17.7 39.9 35.7 18.0 24.0 30.6 18.5 20.0 23.0 17.0 18.8 43.3 27.8 66.7 15.1 45.3 22.6 40.5 9.3 16.6 7.4 9.3 8.7 21.8 9.3 9.1 12.2 20.3 8.8 6.9 16.3 7.1 14.7 15.8 12.8 5.9 24.6 24.9 31.2 38.4 25.3 25.6 24.6 24.6 24.5 24.8 25.4 26.2 24.6 25.6 39.7 43.1 75.4 122.6 29.6 21.5 55.8 24.2 43.8 23.0 16.0 40.0 33.6 20.2 20.9 13.8 40.5 60.7 37.2 25.5 34.8 44.6 17.8 27.1 46.6 52.0 72.1 25.7 12.4 23.6 35.2 55.9 46.9 17.8 17.5 36.8 20.8 37.0 62.9 40.3 20.3 45.2 77.9 55.1 15.8 52.1 23.2 65.6 60.8 35.0 26.8 52.3 67.0 27.3 43.0 20.7 60.5 42.6 29.0 70.5 40.2 32.9 26.3 25.3 21.2 43.1 21.9 59.0 123.5 27.2 36.5 10.2 40.3 46.1 AGFG1 "HRB, RAB, RIP" ENSG00000173744 "ArfGAP with FG repeats 1" P52594 2 227472152-227561217 "Predicted intracellular proteins" "Differentiation, mRNA transport, Spermatogenesis, Transport" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 333.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008741 Approved Supported Vesicles NA NA 120000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA008741: AB_1850752" "unprognostic (5.76e-2)" "prognostic unfavorable (7.13e-4)" "unprognostic (8.73e-3)" "unprognostic (6.31e-3)" "prognostic favorable (6.10e-4)" "unprognostic (9.30e-3)" "prognostic unfavorable (7.31e-6)" "prognostic unfavorable (1.85e-4)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.43e-5)" "unprognostic (2.03e-2)" "unprognostic (5.78e-2)" "prognostic unfavorable (6.92e-4)" "unprognostic (1.25e-1)" "unprognostic (2.37e-1)" "unprognostic (1.98e-1)" "unprognostic (4.24e-3)" 69.4 39.4 30.4 48.4 31.6 155.5 51.1 29.3 36.0 25.3 23.8 32.2 43.4 25.7 20.1 47.2 27.3 38.9 36.2 32.4 27.0 36.9 36.2 54.6 47.1 34.6 29.0 26.1 35.0 41.6 17.9 75.8 33.4 21.0 33.0 47.7 27.9 23.4 33.9 36.3 36.2 39.3 33.6 46.5 33.2 92.8 34.5 48.6 34.3 38.6 53.3 65.7 32.2 47.3 60.5 97.9 50.8 49.6 84.8 62.1 191.6 78.4 74.6 92.0 81.2 77.4 67.6 42.7 58.3 86.8 123.8 62.2 87.9 101.7 118.6 72.3 48.9 94.1 80.8 144.3 90.9 64.7 57.0 38.3 106.4 116.7 109.5 70.3 93.7 43.3 100.3 112.0 111.8 85.8 77.8 58.0 79.3 80.4 50.4 70.8 83.6 30.3 91.7 81.5 47.0 36.7 64.1 82.5 74.7 87.6 35.3 72.4 92.7 78.8 63.0 114.7 70.0 64.5 46.9 59.6 85.6 54.4 92.5 4.1 5.3 1.9 1.6 4.3 3.2 2.0 1.8 1.5 3.3 3.5 1.5 2.8 5.6 1.1 4.2 2.3 2.3 1.6 30.4 31.6 29.3 36.0 32.4 27.0 34.6 29.0 33.4 33.6 34.5 47.3 36.6 25.6 23.6 45.7 27.2 33.1 37.5 18.0 18.2 37.7 29.3 22.1 23.3 17.2 19.6 22.0 25.0 31.0 26.5 28.2 15.6 17.5 162.3 32.7 34.9 29.1 34.1 13.3 114.2 21.5 17.5 26.8 39.8 65.8 12.7 30.4 23.6 22.9 24.1 43.7 74.9 20.4 12.2 92.8 33.6 333.2 15.5 67.3 19.6 119.9 48.4 43.3 19.6 109.6 116.0 32.6 18.0 11.7 22.7 39.4 31.3 27.4 15.5 35.4 19.7 83.8 21.7 72.6 18.4 25.0 32.1 39.7 24.0 20.6 22.2 57.9 AGTRAP ATRAP ENSG00000177674 "Angiotensin II receptor associated protein" Q6RW13 1 11736084-11754802 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 446.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 196.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044120 Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" Vesicles "Golgi apparatus" "HPA044120: AB_10960748" "unprognostic (1.08e-3)" "unprognostic (2.98e-3)" "unprognostic (6.10e-2)" "unprognostic (1.59e-1)" "unprognostic (1.69e-1)" "unprognostic (7.92e-3)" "prognostic unfavorable (6.57e-7)" "unprognostic (4.44e-2)" "unprognostic (7.96e-2)" "unprognostic (4.31e-2)" "unprognostic (1.61e-2)" "unprognostic (7.22e-2)" "unprognostic (1.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (2.33e-3)" "unprognostic (5.89e-2)" 44.1 50.3 26.6 30.2 28.5 132.3 44.3 27.1 32.4 34.6 44.0 29.3 11.2 24.7 47.7 53.6 48.3 25.2 37.0 24.5 30.5 65.8 29.5 62.3 23.4 37.3 28.8 26.9 67.3 25.7 31.2 22.0 31.3 79.1 9.3 3.4 39.0 21.0 54.3 38.8 25.7 20.3 28.4 83.4 33.7 24.7 31.8 11.3 40.8 12.4 13.3 43.9 43.3 31.1 55.9 66.7 16.7 36.9 27.5 34.9 30.5 28.6 49.0 34.8 30.2 42.0 129.7 5.4 126.7 35.4 87.3 45.8 27.9 135.3 10.7 3.1 61.5 1.6 38.4 51.8 84.9 27.6 64.3 34.6 105.4 112.9 59.2 42.4 46.9 17.3 73.8 52.8 19.8 44.6 13.7 80.9 29.7 24.0 67.3 4.6 15.0 27.5 56.7 5.2 14.6 22.0 52.5 26.4 48.4 22.3 59.8 57.4 26.0 44.1 30.8 70.3 30.9 19.6 24.2 33.3 111.7 196.1 20.7 483.4 844.2 694.6 185.7 442.7 90.4 47.0 66.9 109.8 312.2 38.2 72.0 93.5 756.8 73.0 385.2 25.5 90.8 577.4 26.6 28.5 27.1 32.4 24.5 30.5 37.3 28.8 31.3 28.4 31.8 31.1 46.2 22.4 27.4 3.9 12.1 11.6 30.7 112.4 16.5 1.0 54.8 56.0 12.0 32.9 41.6 36.8 6.2 15.7 60.1 6.9 9.8 95.5 20.6 75.3 30.8 36.1 7.2 21.0 0.2 446.7 92.4 45.3 11.2 41.1 88.0 19.1 42.1 7.7 118.3 3.3 0.2 12.3 20.3 143.5 18.9 23.4 37.9 97.8 28.4 1.9 107.4 19.4 122.6 0.5 7.0 96.9 22.5 27.1 8.6 66.5 8.6 55.3 78.5 5.6 13.1 13.0 23.8 3.5 36.1 34.4 13.5 13.1 45.0 50.4 18.2 25.2 AGXT "AGT, AGT1, AGXT1, PH1, SPAT, SPT" ENSG00000172482 "Alanine--glyoxylate and serine--pyruvate aminotransferase" P21549 2 240868824-240880502 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 315 "liver: 2199.2" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 2037.9" "Cancer enriched" "Detected in some" 425 "liver cancer: 253.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035370, HPA035371" Enhanced Supported Vesicles NA NA 4700000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA035370: AB_10673218, HPA035371: AB_2674593" "unprognostic (3.14e-2)" "unprognostic (2.58e-1)" "unprognostic (3.37e-4)" "unprognostic (1.04e-1)" "unprognostic (1.23e-2)" "unprognostic (9.56e-2)" "prognostic favorable (5.92e-5)" "unprognostic (8.28e-2)" "unprognostic (2.77e-1)" "unprognostic (5.39e-2)" "unprognostic (1.55e-1)" "unprognostic (7.57e-3)" "unprognostic (2.54e-1)" "unprognostic (9.22e-2)" "unprognostic (1.37e-1)" "unprognostic (3.26e-2)" 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.9 2199.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 44.3 0.1 7.3 0.0 0.7 0.0 7.6 23.5 0.1 0.1 0.2 0.0 2.8 9.0 128.4 0.0 1.7 26.7 0.4 0.0 0.4 0.0 0.0 52.5 2037.9 0.2 0.0 0.0 8.1 4.1 53.5 0.0 1.6 0.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 12.8 0.4 0.0 0.8 1.9 343.9 0.1 0.0 0.0 2.7 0.1 0.1 0.0 0.0 0.0 1.9 5.2 0.1 1.5 0.4 AIFM2 "AMID, FLJ14497, PRG3" ENSG00000042286 "Apoptosis inducing factor mitochondria associated 2" Q9BRQ8 10 70098223-70132934 "Predicted intracellular proteins" "DNA-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 173.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028961, HPA042309, HPA075576" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Plasma membrane, Cytosol" "HPA028961: AB_2672844, HPA042309: AB_10796575, HPA075576: " "unprognostic (6.62e-2)" "unprognostic (2.73e-1)" "unprognostic (4.29e-1)" "prognostic favorable (2.80e-4)" "unprognostic (7.26e-3)" "unprognostic (2.57e-2)" "unprognostic (7.95e-3)" "unprognostic (2.80e-1)" "unprognostic (5.31e-2)" "unprognostic (8.90e-2)" "unprognostic (2.23e-1)" "unprognostic (1.53e-1)" "unprognostic (4.49e-1)" "unprognostic (4.59e-3)" "unprognostic (2.17e-1)" "unprognostic (1.11e-1)" "prognostic favorable (2.92e-4)" 39.6 13.5 7.5 6.3 8.1 1.9 31.2 7.3 8.0 6.9 8.6 12.9 9.3 7.8 9.0 13.3 6.8 5.0 17.0 6.9 7.7 10.4 21.9 9.3 5.1 8.2 7.3 7.9 5.0 3.2 5.6 4.1 6.9 9.9 7.1 2.4 7.6 7.7 9.8 5.6 11.5 5.0 6.2 7.7 9.9 3.9 8.3 2.4 14.6 7.3 3.6 12.0 6.3 6.5 26.5 45.2 1.1 11.3 26.2 9.8 0.3 10.4 25.5 21.0 23.6 35.3 49.8 3.8 25.8 14.5 27.5 27.9 12.7 3.8 5.9 50.8 1.9 0.2 27.3 173.3 56.1 0.3 6.4 13.3 8.4 33.8 7.2 13.2 9.5 1.7 20.5 21.9 11.0 33.5 1.2 1.3 4.5 21.2 14.6 0.8 4.2 12.4 11.4 19.2 3.6 0.8 19.1 16.6 29.8 1.8 0.7 7.2 12.0 0.5 25.3 15.6 30.8 16.2 32.7 7.3 14.0 0.9 13.9 1.0 0.5 0.5 1.8 0.5 1.5 1.7 0.6 1.5 0.4 1.5 0.8 1.3 0.5 4.0 0.5 0.2 1.3 0.7 7.5 8.1 7.3 8.0 6.9 7.7 8.2 7.3 6.9 6.2 8.3 6.5 11.6 6.4 14.1 7.2 5.0 2.3 15.0 8.4 2.8 5.7 5.5 4.7 13.8 8.6 10.5 18.4 0.0 13.9 1.4 53.1 3.9 40.7 24.1 6.0 7.7 4.8 12.0 7.0 8.2 21.9 3.0 11.2 14.3 6.2 11.4 22.3 1.8 25.0 10.2 1.7 5.2 7.1 14.2 3.3 3.3 47.0 5.3 6.7 8.8 4.7 34.4 4.8 1.0 5.5 3.5 40.8 22.7 4.5 17.0 14.6 28.7 22.6 9.5 2.1 19.7 11.8 12.8 6.2 3.9 5.1 1.4 18.6 3.8 8.8 13.7 20.4 AMACR "P504S, RACE" ENSG00000242110 "Alpha-methylacyl-CoA racemase" Q9UHK6 5 33986165-34008104 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 134.3;liver: 180.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.7;Hepatocytes: 21.6;Late spermatids: 21.6;Proximal tubular cells: 38.5" "Group enriched" "Detected in all" 4 "liver cancer: 8.8;prostate cancer: 34.5;renal cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 175.4;U-266/84: 98.0" "Low region specificity" "Detected in all" "CAB001809, HPA019527, HPA020912" Enhanced Supported "Vesicles,Plasma membrane" NA NA 70000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "CAB001809: AB_2305454, HPA019527: AB_10669651, HPA020912: AB_10670034" "unprognostic (8.96e-2)" "unprognostic (5.20e-3)" "prognostic favorable (7.11e-4)" "unprognostic (9.55e-2)" "unprognostic (1.39e-1)" "unprognostic (9.12e-3)" "unprognostic (1.68e-1)" "unprognostic (5.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.60e-1)" "unprognostic (5.59e-5)" "unprognostic (1.95e-2)" "unprognostic (5.52e-3)" "unprognostic (6.32e-2)" "unprognostic (3.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" 8.6 15.0 5.9 5.0 5.5 3.0 6.4 4.6 6.0 6.5 4.6 40.0 18.0 4.7 9.6 15.6 6.2 20.5 10.1 5.4 7.8 134.3 180.6 9.2 3.6 5.9 6.4 7.8 13.8 13.0 5.7 7.7 6.6 39.3 42.9 12.0 60.7 12.5 19.2 4.9 15.9 7.0 5.8 5.4 34.8 4.3 8.4 4.8 8.3 14.9 5.6 8.8 8.5 5.8 12.7 20.2 11.1 14.3 7.7 11.9 19.1 16.6 12.2 7.6 5.7 66.1 15.1 4.1 8.7 23.6 28.6 5.8 2.8 12.0 7.7 12.7 10.9 9.8 13.7 19.0 5.4 6.0 3.0 18.1 6.0 9.7 3.6 10.7 8.5 8.3 3.8 14.7 22.4 9.6 5.0 7.6 10.0 9.4 32.9 6.0 18.6 6.5 33.2 62.4 6.1 8.7 27.6 19.3 16.9 9.1 14.9 5.9 15.6 24.6 5.4 6.2 13.6 175.4 98.0 7.4 7.0 12.1 18.8 0.3 6.0 9.3 8.3 8.0 7.0 7.1 7.2 6.4 8.9 5.2 6.6 4.8 10.0 8.7 14.2 4.6 7.9 6.0 5.9 5.5 4.6 6.0 5.4 7.8 5.9 6.4 6.6 5.8 8.4 5.8 0.8 3.2 4.1 0.0 2.2 0.4 0.4 0.9 1.8 4.3 1.4 0.9 1.1 8.6 3.7 1.8 0.0 1.0 2.2 19.7 5.9 0.8 8.9 2.3 1.2 3.0 4.2 2.1 0.0 3.8 1.0 2.9 4.1 1.5 0.0 1.2 1.1 21.6 1.1 5.0 0.0 5.1 4.1 0.9 0.2 21.6 0.6 1.2 0.0 0.0 1.5 9.3 3.1 0.0 0.0 2.6 4.5 2.2 1.6 0.6 4.7 38.5 3.1 0.9 0.0 1.7 3.7 0.7 0.7 3.4 0.6 0.3 1.5 1.2 4.4 0.4 ANKRD13B FLJ25555 ENSG00000198720 "Ankyrin repeat domain 13B" Q86YJ7 17 29589769-29614761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 27.4;Endometrial stromal cells: 24.2;Excitatory neurons: 19.4;Horizontal cells: 16.8;Late spermatids: 44.7;Oligodendrocytes: 17.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 52.0;SH-SY5Y: 57.6;SK-BR-3: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051886, HPA063748" Uncertain Supported Vesicles NA NA "Cluster 43: Testis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA051886: AB_2681652, HPA063748: AB_2685112" "unprognostic (1.61e-1)" "unprognostic (2.01e-1)" "unprognostic (1.27e-1)" "unprognostic (1.66e-2)" "unprognostic (1.53e-1)" "unprognostic (2.45e-1)" "unprognostic (3.10e-4)" "unprognostic (1.84e-1)" "unprognostic (1.84e-1)" "unprognostic (1.03e-2)" "prognostic favorable (7.58e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (5.92e-6)" "unprognostic (9.93e-2)" "unprognostic (1.18e-1)" "unprognostic (3.94e-2)" "unprognostic (5.36e-3)" 12.0 3.7 12.5 1.7 14.3 0.7 7.5 11.9 15.9 16.3 0.0 10.2 0.8 13.6 0.8 6.5 12.0 3.7 10.3 13.9 6.2 2.8 1.2 5.5 1.6 13.4 9.4 15.1 3.7 1.6 14.6 0.9 10.4 7.7 0.6 2.0 4.3 1.8 9.6 7.5 4.5 2.9 7.2 2.6 4.9 18.9 10.8 0.9 5.8 1.3 0.3 10.0 11.6 22.9 6.6 11.5 13.3 35.4 8.2 8.0 5.1 2.0 1.2 1.4 2.7 6.1 1.4 7.4 6.4 2.8 4.9 24.3 7.2 7.8 0.2 14.8 23.5 2.3 22.3 5.3 3.5 2.4 4.6 7.9 10.2 2.2 5.8 6.4 10.1 12.8 6.0 6.1 1.9 5.9 16.0 7.5 11.4 6.8 9.7 33.4 9.5 23.4 3.0 2.2 52.0 57.6 3.9 48.0 4.3 1.2 7.4 4.4 6.7 7.4 7.2 5.2 7.2 11.4 15.7 9.2 5.2 12.1 4.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 14.3 11.9 15.9 13.9 6.2 13.4 9.4 10.4 7.2 10.8 22.9 2.6 0.0 0.0 6.8 0.1 1.7 1.0 0.7 3.4 4.5 1.8 2.7 2.3 0.0 0.4 0.0 2.1 0.1 0.6 0.6 1.9 1.6 27.4 0.9 24.2 2.4 3.0 1.7 19.4 0.6 0.2 5.5 2.6 1.0 0.0 3.8 1.4 0.6 0.1 16.8 14.6 0.8 0.0 0.3 1.6 44.7 14.6 0.3 0.0 0.0 0.0 1.8 0.0 11.1 17.8 0.5 0.0 7.5 0.5 3.2 0.1 0.2 0.0 5.2 0.0 2.4 2.5 6.0 4.7 2.6 1.7 0.1 0.7 1.0 1.1 1.5 ANKRD27 "DKFZp434L0718, FLJ00040, VARP" ENSG00000105186 "Ankyrin repeat domain 27" Q96NW4 19 32597006-32676597 "Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 137.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042769 Approved Supported Vesicles,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" Vesicles Cytosol "HPA042769: AB_10796584" "unprognostic (2.16e-3)" "unprognostic (6.04e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (1.63e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (1.21e-5)" "unprognostic (9.02e-2)" "unprognostic (1.07e-1)" "unprognostic (1.61e-2)" "unprognostic (2.90e-2)" "unprognostic (6.22e-3)" "unprognostic (3.74e-2)" "unprognostic (2.14e-1)" "unprognostic (4.94e-2)" "unprognostic (4.07e-1)" "unprognostic (2.26e-2)" 8.9 7.4 10.8 8.9 12.9 10.4 8.7 12.1 12.6 10.3 21.5 17.2 7.6 10.0 8.8 14.3 8.0 7.7 9.6 11.8 9.8 9.7 4.4 10.3 11.1 12.0 12.9 8.3 7.2 9.3 6.8 13.6 12.4 12.3 11.9 11.7 9.7 13.5 20.7 12.4 10.7 11.6 8.9 9.0 11.0 17.3 12.1 16.7 13.3 10.8 11.5 16.9 11.1 11.8 32.0 36.0 11.5 20.8 23.5 18.0 28.1 18.0 18.0 19.4 25.4 28.8 19.0 34.7 16.5 23.0 20.4 19.4 29.6 22.3 32.0 47.3 15.1 137.9 13.7 23.9 29.4 53.5 47.6 13.1 28.8 20.9 33.8 13.5 19.7 25.3 37.5 76.3 15.1 31.5 20.8 46.2 6.0 40.2 13.8 30.6 15.6 12.7 15.6 30.5 21.3 8.6 17.6 29.6 21.0 15.2 12.4 25.7 18.5 21.1 22.4 19.6 28.0 19.7 12.7 23.8 21.0 51.8 13.8 36.5 11.1 28.5 13.9 15.7 17.5 7.5 14.3 15.6 12.6 6.9 10.9 11.7 9.0 30.6 13.3 6.2 13.2 13.3 10.8 12.9 12.1 12.6 11.8 9.8 12.0 12.9 12.4 8.9 12.1 11.8 6.8 16.0 9.4 18.3 10.0 15.6 5.5 5.6 14.2 9.4 9.0 5.1 9.2 7.2 5.7 9.2 20.9 14.9 9.7 9.3 0.0 3.3 5.1 7.5 9.4 7.1 9.1 26.5 35.5 5.9 10.6 7.6 5.6 11.6 12.0 10.1 4.6 4.8 8.4 11.8 16.3 9.6 8.2 12.0 12.1 16.2 10.8 8.7 16.0 12.2 6.0 5.8 9.2 11.1 18.7 7.1 10.3 9.4 8.0 10.0 10.8 7.7 7.1 14.7 0.0 6.8 9.3 4.1 17.1 14.7 15.5 15.2 14.0 7.2 8.9 8.4 AP1B1 "ADTB1, AP105A, BAM22, CLAPB2" ENSG00000100280 "Adaptor related protein complex 1 subunit beta 1" Q10567 22 29327680-29388583 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065226, HPA068520" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 660000 "Cluster 39: Non-specific - mRNA processing" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "Vesicles, Cytosol" "HPA065226: AB_2685438, HPA068520: AB_2685998" "unprognostic (1.78e-1)" "prognostic favorable (4.81e-4)" "unprognostic (2.40e-1)" "unprognostic (2.21e-2)" "unprognostic (2.37e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.55e-5)" "unprognostic (4.99e-2)" "unprognostic (1.59e-1)" "unprognostic (1.27e-1)" "unprognostic (4.98e-3)" "unprognostic (1.60e-1)" "prognostic favorable (7.24e-6)" "unprognostic (1.85e-2)" "unprognostic (3.78e-2)" "unprognostic (2.94e-2)" "unprognostic (3.76e-2)" 30.7 46.7 38.0 47.2 38.3 45.8 26.4 37.3 45.2 22.8 35.6 34.9 43.3 22.7 12.1 63.0 23.5 30.4 23.9 36.1 40.8 34.8 34.8 30.1 57.8 44.2 44.6 17.5 38.3 67.0 39.2 44.8 43.7 38.3 30.1 35.3 40.3 25.9 24.5 47.2 45.6 27.1 41.4 52.6 40.9 24.7 52.7 34.2 29.6 20.5 54.4 39.4 32.2 48.8 84.6 47.5 49.3 50.2 37.0 27.0 60.0 59.8 65.5 71.2 68.2 74.4 33.2 46.1 37.2 68.4 33.0 74.6 71.5 97.6 45.2 58.2 102.0 79.1 60.8 42.0 38.9 114.1 99.9 38.6 36.0 67.5 55.0 33.0 98.7 17.2 54.6 54.9 48.3 93.7 45.5 36.8 37.3 124.8 53.3 89.0 54.3 119.9 50.2 194.5 75.9 52.2 74.0 82.5 36.4 33.5 66.7 49.5 84.6 79.1 48.8 46.0 62.1 60.4 32.5 84.6 56.1 48.1 46.7 0.0 29.3 5.7 9.2 29.2 9.1 16.2 6.3 7.9 28.7 18.2 4.9 5.2 3.0 7.2 31.7 9.0 8.8 24.2 38.0 38.3 37.3 45.2 36.1 40.8 44.2 44.6 43.7 41.4 52.7 48.8 17.8 12.8 16.4 27.7 53.0 7.1 9.3 16.7 16.5 26.3 26.2 20.8 16.1 21.5 16.4 22.0 39.6 52.3 15.1 69.6 23.5 41.2 7.5 16.4 11.6 19.8 21.6 40.0 24.1 40.7 30.1 12.1 33.6 30.1 5.1 13.2 35.3 34.3 138.9 45.4 25.6 24.9 18.3 95.5 24.2 13.1 11.8 65.7 12.4 51.5 29.8 28.4 9.2 16.1 14.0 65.9 33.2 12.4 28.5 17.5 51.2 30.1 14.5 42.1 6.6 17.8 12.7 23.5 17.6 33.0 9.1 68.3 17.0 39.6 36.2 18.1 AP1M2 "AP1-mu2, HSMU1B, mu2" ENSG00000129354 "Adaptor related protein complex 1 subunit mu 2" Q9Y6Q5 19 10572671-10587315 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 162.0;Proximal tubular cells: 373.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.3;neutrophil: 7.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.6" "Cell line enhanced" "Detected in many" "CACO-2: 172.8;Hep G2: 313.8;MCF7: 268.3;OE19: 156.7;RT4: 164.9;U-2 OS: 166.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA054999 Supported Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA054999: AB_2682666" "unprognostic (8.31e-2)" "unprognostic (2.38e-1)" "unprognostic (1.87e-1)" "prognostic favorable (2.07e-4)" "unprognostic (2.07e-1)" "unprognostic (7.76e-2)" "unprognostic (2.11e-3)" "unprognostic (4.83e-2)" "unprognostic (1.93e-1)" "unprognostic (2.49e-2)" "unprognostic (2.65e-1)" "unprognostic (2.23e-2)" "prognostic favorable (3.73e-6)" "unprognostic (1.80e-2)" "unprognostic (8.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.06e-1)" 3.4 0.1 0.8 6.4 0.3 0.9 32.9 0.6 0.8 27.1 0.3 67.1 64.0 6.6 61.8 51.9 46.6 22.7 0.4 0.5 0.4 76.3 1.5 19.2 0.4 0.7 0.6 0.3 55.9 62.4 34.8 16.2 0.4 30.8 63.4 0.1 41.5 24.0 0.3 42.1 54.8 3.0 0.3 0.6 59.1 9.6 0.7 4.2 58.8 0.3 9.5 23.4 19.1 0.6 144.2 71.1 0.4 10.4 0.0 0.0 65.0 0.2 0.0 2.3 1.6 172.8 82.1 0.4 64.7 1.2 43.4 97.6 0.1 109.0 3.2 0.6 1.0 6.7 48.5 313.8 1.3 0.3 0.8 0.2 81.6 3.9 0.1 5.0 0.0 0.4 0.3 0.6 1.2 268.3 0.6 1.8 31.4 156.7 0.0 2.4 9.3 0.7 2.7 164.9 67.3 0.2 0.0 120.0 0.6 34.6 123.3 0.4 0.0 0.4 166.7 0.9 2.2 0.4 0.9 1.4 0.2 0.4 0.2 4.3 0.4 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 7.6 0.0 1.4 0.2 0.0 2.7 0.8 0.3 0.6 0.8 0.5 0.4 0.7 0.6 0.4 0.3 0.7 0.6 0.4 28.9 34.8 0.0 1.9 6.9 19.2 68.9 13.1 0.0 49.3 30.0 0.5 47.1 64.2 86.5 0.0 123.0 0.5 112.2 137.0 141.3 43.4 52.4 5.4 1.7 74.4 0.0 0.3 115.8 101.0 1.5 73.4 57.7 2.5 0.0 0.7 0.0 9.8 0.0 0.2 95.5 97.6 0.8 0.0 19.9 1.5 2.6 3.6 0.0 1.7 0.0 0.0 0.0 0.2 130.2 125.6 0.7 0.0 37.6 162.0 373.6 61.5 0.0 0.0 0.0 6.2 16.9 4.1 39.1 13.1 66.1 2.8 0.0 131.4 48.3 AP1S1 "AP19, CLAPS1, EKV3, SIGMA1A, WUGSC:H_DJ0747G18.2" ENSG00000106367 "Adaptor related protein complex 1 subunit sigma 1" P61966 7 101154456-101161596 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Ichthyosis, Mental retardation, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 344.4;Proximal enterocytes: 241.3;Proximal tubular cells: 304.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060945 Supported Supported "Golgi apparatus,Vesicles" NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus, Vesicles" "HPA060945: AB_2684393" "unprognostic (1.98e-2)" "unprognostic (5.41e-3)" "unprognostic (1.02e-1)" "unprognostic (3.34e-2)" "unprognostic (2.98e-3)" "unprognostic (8.70e-3)" "unprognostic (7.06e-3)" "unprognostic (1.12e-1)" "unprognostic (1.76e-1)" "unprognostic (7.79e-2)" "unprognostic (1.34e-1)" "unprognostic (3.75e-2)" "unprognostic (2.81e-2)" "unprognostic (2.14e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" 14.4 24.6 72.2 13.9 75.7 5.8 17.2 43.7 82.6 18.3 34.6 28.6 39.0 16.9 17.0 34.2 13.8 12.8 11.8 85.2 59.6 41.2 36.2 14.7 11.9 53.6 51.9 13.5 21.9 22.8 31.0 15.9 53.4 22.2 22.4 14.6 20.3 9.3 6.4 39.2 30.3 12.7 46.1 20.2 22.0 16.4 62.5 19.1 15.2 8.5 13.6 20.1 19.5 62.7 121.0 87.3 63.3 118.4 42.8 70.4 138.2 76.8 51.1 50.8 52.8 47.3 147.5 24.9 127.5 84.6 97.1 59.0 35.3 116.0 45.6 57.0 56.6 16.8 52.0 61.4 54.2 46.8 87.7 79.1 91.0 49.4 20.6 76.7 76.8 54.1 56.7 103.2 129.9 292.1 40.4 107.8 97.8 177.0 188.2 24.9 27.2 54.6 127.8 88.8 47.5 157.7 40.4 121.1 151.4 101.6 50.7 46.8 79.0 74.1 132.3 27.6 55.2 21.4 51.4 48.4 195.2 50.1 152.9 0.5 3.3 0.3 2.3 3.1 2.2 2.6 3.2 2.5 4.6 2.0 1.9 1.8 1.2 1.3 1.8 5.0 3.3 2.4 72.2 75.7 43.7 82.6 85.2 59.6 53.6 51.9 53.4 46.1 62.5 62.7 34.4 6.4 0.0 2.3 17.9 38.7 29.7 173.0 46.7 30.7 54.8 49.0 1.1 45.8 72.9 55.2 8.4 170.7 19.8 88.4 344.4 128.2 2.5 28.8 34.2 36.7 90.3 16.2 21.2 111.7 101.3 27.7 42.8 31.9 5.7 85.3 28.9 43.0 95.2 30.3 10.3 96.5 116.0 24.8 21.6 3.4 35.1 27.3 53.4 7.5 58.0 34.1 17.5 2.5 9.8 183.3 86.1 21.8 17.4 34.9 241.3 304.8 34.9 22.3 19.7 11.4 38.4 13.1 70.9 51.4 45.5 60.5 19.5 157.4 119.9 38.2 AP1S2 "MRX59, MRXS5, PGS, SIGMA1B" ENSG00000182287 "Adaptor related protein complex 1 subunit sigma 2" P56377 X 15825806-15854931 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "epididymis: 663.3" "Cell type enhanced" "Detected in all" "Hofbauer cells: 259.8;Kupffer cells: 392.6;Langerhans cells: 609.2;Macrophages: 362.7;monocytes: 630.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 13.1;glioma: 22.0;melanoma: 49.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 326.8;intermediate monocyte: 325.0;myeloid DC: 221.1;non-classical monocyte: 175.4;plasmacytoid DC: 82.2" "Group enriched" "Detected in all" 5 "dendritic cells: 221.1;monocytes: 326.8" "Cell line enhanced" "Detected in all" "Karpas-707: 298.0;SK-MEL-30: 442.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049894, HPA060945" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Vesicles" "HPA049894: AB_2680939, HPA060945: AB_2684393" "prognostic favorable (9.86e-4)" "unprognostic (4.62e-2)" "unprognostic (2.11e-1)" "unprognostic (1.68e-1)" "unprognostic (2.47e-3)" "unprognostic (3.85e-1)" "unprognostic (2.03e-3)" "unprognostic (5.76e-2)" "unprognostic (1.43e-2)" "prognostic favorable (5.53e-6)" "unprognostic (1.85e-2)" "unprognostic (5.61e-2)" "unprognostic (5.08e-2)" "unprognostic (6.35e-2)" "unprognostic (3.13e-1)" "unprognostic (9.34e-2)" "unprognostic (6.47e-2)" 28.3 21.4 24.6 36.7 28.4 38.3 15.0 32.0 36.9 31.6 27.3 42.1 11.9 52.2 663.3 21.4 13.5 20.1 74.8 25.1 48.0 13.1 15.9 25.8 33.2 42.7 35.8 8.8 7.8 16.7 19.4 42.0 47.0 11.6 22.0 43.7 9.5 30.5 70.1 14.0 20.1 76.3 34.4 43.0 19.5 23.4 29.6 28.7 12.5 93.7 28.8 26.1 12.7 33.8 12.0 14.2 130.1 78.4 29.5 19.1 5.0 47.1 22.7 31.1 41.1 9.6 11.1 22.6 183.0 72.6 50.4 16.1 31.7 10.8 57.0 30.1 64.9 15.3 16.7 14.7 24.2 63.1 16.9 12.2 11.2 36.0 33.1 50.4 78.1 19.1 14.3 298.0 72.4 8.7 12.9 39.5 171.0 6.4 42.5 29.5 116.7 50.6 37.4 2.5 14.8 69.2 18.4 4.8 442.2 84.1 52.7 69.2 43.9 67.8 21.2 92.5 41.9 25.5 58.7 37.3 33.6 28.0 159.7 50.9 326.8 34.6 21.1 325.0 24.8 30.8 25.5 20.6 221.1 28.0 18.5 18.1 52.8 27.9 175.4 82.2 38.1 228.0 24.6 28.4 32.0 36.9 25.1 48.0 42.7 35.8 47.0 34.4 29.6 33.8 130.8 3.2 13.1 37.2 77.0 55.2 12.7 9.1 8.6 34.7 12.0 11.4 195.6 12.8 3.2 9.2 12.5 5.3 114.2 9.2 33.2 13.7 5.1 50.4 32.6 166.3 26.9 32.6 15.1 6.4 18.9 38.0 7.7 78.0 78.6 15.6 147.4 8.6 259.8 11.8 73.2 8.4 12.2 392.6 609.2 17.5 17.4 362.7 149.4 31.9 630.0 21.1 62.8 19.1 85.0 10.3 14.0 7.2 26.0 19.0 6.5 9.0 1.6 39.3 39.5 26.7 39.1 55.7 28.8 10.6 51.6 5.6 58.3 4.0 8.5 6.7 AP1S3 ENSG00000152056 "Adaptor related protein complex 1 subunit sigma 3" Q96PC3 2 223751686-223838027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 52.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Cytotrophoblasts: 48.2;Pancreatic endocrine cells: 44.2;Urothelial cells: 69.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.9;dendritic cells: 4.0;granulocytes: 4.9" "Cell line enhanced" "Detected in many" "CACO-2: 151.1;RPTEC TERT1: 56.8;RT4: 52.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066782 Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA066782: AB_2685720" "unprognostic (9.45e-3)" "unprognostic (1.79e-1)" "unprognostic (7.52e-2)" "unprognostic (5.80e-2)" "unprognostic (4.37e-2)" "unprognostic (4.89e-1)" "unprognostic (1.65e-3)" "prognostic unfavorable (3.36e-5)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.08e-5)" "unprognostic (1.56e-1)" "unprognostic (2.33e-1)" "unprognostic (2.50e-2)" "unprognostic (1.90e-1)" "unprognostic (2.32e-2)" "unprognostic (4.61e-2)" 0.7 0.8 3.4 3.3 3.2 4.0 2.1 3.9 3.5 2.2 0.5 2.7 5.3 0.9 52.8 4.8 2.3 5.2 0.5 2.8 3.0 5.6 1.4 4.7 4.2 2.0 1.6 0.5 2.4 3.8 1.1 6.6 1.5 2.9 2.6 5.7 1.6 5.4 0.9 1.9 5.0 0.7 1.1 2.8 9.8 0.9 3.2 1.6 14.4 0.3 5.2 8.1 1.2 2.1 28.7 17.7 2.4 12.0 1.5 0.6 13.5 11.5 2.4 4.9 4.2 151.1 21.8 11.0 8.0 1.7 5.8 43.8 6.4 30.3 6.8 15.3 8.9 1.2 33.7 15.7 0.6 3.4 1.3 0.6 31.2 9.1 30.1 11.2 3.4 5.8 1.8 2.9 2.9 12.3 0.6 0.9 3.8 32.8 15.5 4.3 0.1 4.5 56.8 52.1 7.4 2.1 5.4 11.8 3.8 6.1 5.0 6.3 2.0 1.6 4.6 3.1 9.2 10.2 9.0 28.2 4.4 2.0 6.0 4.9 0.5 0.3 0.6 0.4 0.5 4.9 0.4 0.4 1.2 2.7 0.4 0.5 1.8 0.6 0.2 4.0 1.0 0.4 3.4 3.2 3.9 3.5 2.8 3.0 2.0 1.6 1.5 1.1 3.2 2.1 0.4 35.3 6.7 8.8 24.2 4.2 32.6 15.3 4.0 3.3 4.3 1.8 1.7 0.0 15.8 11.0 64.6 48.2 13.6 3.6 9.8 17.5 0.2 8.1 2.1 2.1 2.4 0.0 19.3 18.1 3.4 3.5 11.7 26.1 3.8 0.8 0.7 0.4 4.7 6.7 9.6 3.6 16.2 1.6 38.1 0.0 0.3 7.5 3.6 4.7 7.4 1.9 6.2 10.6 4.0 44.2 4.6 0.0 10.7 26.6 5.4 4.5 10.3 5.9 0.0 1.1 1.8 0.3 1.9 6.3 4.1 13.1 6.9 1.0 4.7 69.6 AP2A1 "ADTAA, CLAPA1" ENSG00000196961 "Adaptor related protein complex 2 subunit alpha 1" O95782 19 49767001-49807114 "Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 165.0;Syncytiotrophoblasts: 241.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 20.5" "Lineage enriched" "Detected in all" 4 "monocytes: 20.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB004306 Approved Supported Vesicles NA NA 61000 "Cluster 51: Monocytes - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "CAB004306: AB_2274034" "unprognostic (4.33e-2)" "unprognostic (1.52e-1)" "unprognostic (4.61e-1)" "unprognostic (7.18e-2)" "unprognostic (1.88e-1)" "unprognostic (1.23e-1)" "unprognostic (1.92e-2)" "unprognostic (5.85e-3)" "unprognostic (4.84e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (2.82e-2)" "unprognostic (2.38e-2)" "prognostic unfavorable (2.83e-9)" "unprognostic (2.63e-1)" "unprognostic (1.45e-1)" "unprognostic (7.90e-2)" "unprognostic (1.72e-3)" 47.0 87.4 37.4 25.2 47.9 54.4 41.2 20.6 49.2 48.1 9.0 42.2 24.7 56.6 7.4 46.5 48.2 19.6 52.2 44.2 31.8 33.3 51.1 37.2 19.5 45.8 31.4 57.1 33.8 13.9 34.3 31.4 45.3 33.0 9.9 13.9 28.9 18.6 89.6 54.2 34.0 21.4 17.8 47.6 36.3 88.8 50.0 15.4 30.5 26.9 13.2 46.0 43.6 35.8 70.9 100.3 33.8 78.7 59.5 72.2 69.0 82.0 55.3 49.7 51.8 52.0 43.5 31.5 30.6 85.2 41.9 62.8 25.7 59.0 21.1 50.1 58.4 46.6 66.1 56.8 65.3 37.7 75.0 113.6 42.3 55.4 28.7 44.2 59.5 51.3 118.5 42.7 47.6 55.8 41.6 50.2 34.6 66.6 101.8 46.6 79.7 40.4 29.6 88.1 25.7 34.7 90.1 61.1 34.3 36.1 52.1 52.9 82.9 128.4 70.6 54.6 59.3 63.1 83.5 33.1 90.5 54.8 55.1 0.3 5.3 3.4 2.0 12.8 1.4 1.2 1.2 1.2 4.6 1.0 0.9 1.3 4.0 2.3 20.5 1.4 1.6 4.8 37.4 47.9 20.6 49.2 44.2 31.8 45.8 31.4 45.3 17.8 50.0 35.8 22.9 0.0 2.3 19.6 18.5 13.8 19.0 18.5 14.8 45.1 26.7 19.0 2.9 14.3 11.7 14.7 43.8 90.8 21.8 39.1 11.7 16.1 129.9 23.0 57.1 22.4 2.4 106.5 24.2 29.4 35.3 36.0 22.4 16.0 8.9 33.2 39.3 36.6 31.3 50.5 25.5 17.4 8.2 56.2 21.3 165.0 53.4 34.0 19.6 14.0 40.4 31.5 63.8 14.1 21.8 27.3 19.0 61.7 28.1 16.3 41.2 50.4 14.9 30.2 59.2 23.2 28.5 54.7 59.2 22.1 13.9 241.6 23.2 48.6 23.9 24.3 AP2A2 "ADTAB, CLAPA2, DKFZP564D1864, HIP9, HYPJ, KIAA0899" ENSG00000183020 "Adaptor related protein complex 2 subunit alpha 2" O94973 11 924894-1012245 "Plasma proteins, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017514, HPA043040" Supported Supported Nucleoplasm,Vesicles NA NA 10000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "CAB017514: AB_2056344, HPA043040: AB_2678283" "unprognostic (1.90e-1)" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (2.09e-2)" "unprognostic (1.28e-2)" "unprognostic (5.72e-2)" "prognostic unfavorable (9.27e-5)" "unprognostic (1.34e-2)" "unprognostic (4.09e-1)" "unprognostic (1.70e-1)" "prognostic favorable (4.57e-4)" "unprognostic (2.41e-1)" "unprognostic (2.86e-3)" "unprognostic (1.05e-1)" "unprognostic (1.58e-1)" "unprognostic (1.40e-1)" "unprognostic (2.08e-2)" 20.1 18.0 3.5 1.3 5.1 4.5 16.6 10.8 9.9 20.3 1.4 23.0 5.4 17.9 1.5 12.7 18.1 2.0 19.1 5.5 3.5 34.4 29.9 18.9 3.2 0.9 2.1 17.5 25.3 3.7 25.6 5.2 3.0 20.3 4.9 5.8 14.6 4.0 14.1 14.5 19.6 5.6 0.0 57.6 20.6 15.5 3.3 3.8 13.9 1.6 2.5 19.0 15.7 1.4 7.5 2.9 3.7 10.7 13.8 14.2 9.1 10.2 3.3 6.0 4.9 1.3 7.3 7.4 8.7 12.3 5.7 8.9 8.9 5.6 3.9 5.5 23.2 2.1 10.4 3.9 5.3 2.8 4.9 16.8 6.1 3.1 6.1 14.8 8.5 5.0 5.9 4.7 6.3 0.4 2.6 3.2 2.0 9.1 17.9 4.2 2.6 8.1 9.2 6.2 12.3 10.0 11.4 9.2 1.7 6.3 5.4 0.8 13.3 1.9 2.3 2.8 5.2 4.3 3.9 5.3 4.0 3.7 3.1 1.5 1.7 1.5 1.1 1.7 0.5 0.5 1.1 0.6 1.4 1.0 1.1 1.2 2.1 1.1 1.4 1.3 2.1 0.6 3.5 5.1 10.8 9.9 5.5 3.5 0.9 2.1 3.0 0.0 3.3 1.4 38.1 38.5 21.8 29.4 14.3 14.3 12.4 13.3 7.4 50.9 27.2 23.0 12.9 21.5 15.9 62.5 60.5 42.1 17.3 45.3 39.2 37.5 46.7 64.0 44.6 36.6 35.2 27.1 37.2 18.0 45.2 28.7 16.3 86.7 27.3 31.0 80.3 59.8 82.8 101.0 36.4 32.3 18.3 104.7 26.9 28.3 34.5 51.8 8.8 41.2 31.2 30.4 39.1 23.1 21.9 25.8 24.2 27.8 13.6 16.9 43.5 70.4 23.5 69.2 26.3 20.7 22.6 72.7 28.0 11.2 11.4 28.5 19.7 30.5 37.0 11.5 AP2B1 "ADTB2, CLAPB1" ENSG00000006125 "Adaptor related protein complex 2 subunit beta 1" P63010 17 35578046-35726413 "Cancer-related genes, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 503.9;Late spermatids: 739.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017631, HPA056733, HPA067983" Approved Supported Vesicles NA NA 380000 "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB017631: AB_2058201, HPA056733: AB_2683219, HPA067983: AB_2732777" "unprognostic (1.49e-2)" "unprognostic (4.04e-3)" "unprognostic (2.15e-3)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-2)" "unprognostic (1.51e-3)" "unprognostic (2.64e-2)" "unprognostic (1.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.58e-2)" "unprognostic (2.50e-1)" "prognostic favorable (2.62e-4)" "unprognostic (1.70e-1)" "unprognostic (1.10e-1)" "unprognostic (3.25e-2)" "unprognostic (1.57e-2)" 46.4 42.4 77.0 38.2 87.8 49.2 58.3 69.9 88.7 54.1 76.6 67.6 33.5 41.7 70.7 25.1 46.7 42.3 67.6 92.1 83.5 69.0 35.0 53.4 38.6 69.8 78.6 57.2 33.2 126.4 55.0 66.8 76.8 40.9 84.0 76.1 41.9 50.1 57.5 29.9 38.8 56.0 80.3 42.0 48.4 93.5 78.7 59.7 65.1 61.0 45.5 46.8 34.4 95.0 188.8 233.9 113.7 132.0 184.4 202.8 51.6 94.3 138.9 131.0 141.1 129.0 154.6 90.5 81.1 175.3 168.8 173.2 162.5 264.8 190.8 108.6 147.0 117.7 161.8 71.0 104.7 119.3 80.8 128.9 104.3 134.5 209.3 151.2 211.4 111.8 190.6 126.9 206.9 36.9 113.7 58.7 94.2 98.9 164.5 94.3 165.1 64.7 166.2 108.3 94.4 114.1 114.5 39.6 126.9 273.3 161.5 78.5 211.5 99.3 93.4 109.8 142.1 53.0 106.1 84.7 124.1 86.9 112.5 19.6 11.8 16.7 16.0 15.3 16.9 12.1 13.9 14.3 10.7 11.9 6.3 8.0 13.3 9.6 16.8 10.7 20.5 11.0 77.0 87.8 69.9 88.7 92.1 83.5 69.8 78.6 76.8 80.3 78.7 95.0 76.5 16.0 17.0 49.3 45.9 31.1 26.3 57.4 70.6 67.6 88.9 50.9 62.5 68.6 37.4 112.2 56.3 29.7 70.7 97.4 117.4 105.0 503.9 74.5 83.7 56.8 71.3 214.7 105.5 120.2 42.8 47.1 36.2 85.4 41.2 46.5 79.9 64.5 44.1 69.0 109.8 79.4 28.5 54.3 25.9 739.2 58.7 37.2 16.0 60.0 47.3 52.6 74.2 81.4 89.0 177.9 46.6 68.4 32.1 37.4 39.4 102.5 30.4 40.9 59.2 25.3 37.6 258.8 60.0 19.6 14.6 32.8 49.2 37.3 89.8 29.1 AP4S1 "AP47B, CLA20, SPG52" ENSG00000100478 "Adaptor related protein complex 4 subunit sigma 1" Q9Y587 14 31025106-31130996 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039963 Approved Supported Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA039963: AB_10795240" "unprognostic (4.03e-2)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (2.43e-1)" "unprognostic (1.14e-1)" "unprognostic (8.00e-3)" "unprognostic (1.03e-1)" "prognostic favorable (7.44e-4)" "unprognostic (3.79e-2)" "unprognostic (8.62e-3)" "unprognostic (1.15e-2)" "unprognostic (3.02e-1)" "prognostic favorable (2.87e-6)" "unprognostic (2.20e-3)" "unprognostic (5.44e-2)" "unprognostic (7.75e-2)" "unprognostic (5.59e-2)" 4.8 6.3 9.8 6.6 10.6 6.0 5.7 14.1 12.8 6.5 5.6 8.6 3.9 7.7 7.0 4.9 7.3 5.4 8.7 9.5 10.2 7.8 6.2 5.4 8.1 6.3 6.5 10.7 7.9 6.5 8.5 6.7 6.1 6.2 4.1 11.9 5.2 6.7 12.6 4.6 4.4 7.9 5.4 8.0 4.3 18.4 9.0 6.6 8.8 7.2 7.7 6.2 4.8 10.1 9.0 12.6 11.0 3.2 4.4 7.9 8.5 6.0 10.4 9.6 9.5 12.2 14.5 10.6 5.5 7.3 7.2 9.7 7.6 9.4 15.9 9.1 4.4 16.4 5.5 19.0 9.5 14.1 9.2 6.3 5.9 9.6 12.0 6.4 11.7 8.0 8.4 7.0 10.3 12.5 9.7 7.8 13.1 10.5 10.9 10.3 9.8 1.4 10.5 12.4 6.1 6.1 10.7 5.1 16.3 7.3 10.8 6.5 8.8 7.3 6.5 5.0 5.2 8.6 17.0 15.9 4.2 4.4 5.7 3.4 1.3 2.4 2.5 3.5 3.7 3.3 3.8 3.0 1.2 3.4 3.7 4.5 2.6 5.8 2.8 3.3 6.6 1.7 9.8 10.6 14.1 12.8 9.5 10.2 6.3 6.5 6.1 5.4 9.0 10.1 7.1 9.6 7.7 10.7 8.1 3.4 6.5 6.5 1.2 12.1 4.0 4.3 16.5 4.3 3.1 5.5 31.3 9.1 7.6 3.9 5.9 7.6 21.9 5.2 8.8 6.7 6.0 3.8 29.4 4.8 5.3 6.2 7.1 5.8 7.6 7.8 10.8 4.0 7.4 6.7 24.9 3.8 4.1 5.4 4.1 17.0 6.8 6.0 3.6 12.2 7.5 9.3 5.2 25.1 16.4 2.8 6.2 8.6 4.2 4.0 5.0 7.7 8.1 24.4 6.6 8.5 8.1 36.0 8.3 3.0 2.8 11.5 7.3 8.2 4.0 5.2 APEX2 "APE2, APEXL2, XTH2, ZGRF2" ENSG00000169188 "Apurinic/apyrimidinic endodeoxyribonuclease 2" Q9UBZ4 X 55000363-55009057 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" "DNA-binding, Endonuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 52.7;Syncytiotrophoblasts: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048577 Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" Vesicles "HPA048577: AB_2680448" "unprognostic (2.90e-2)" "prognostic favorable (6.17e-4)" "unprognostic (4.32e-2)" "unprognostic (2.39e-1)" "unprognostic (1.62e-1)" "unprognostic (5.62e-2)" "prognostic unfavorable (6.13e-7)" "unprognostic (5.89e-2)" "unprognostic (4.87e-2)" "prognostic favorable (5.21e-4)" "unprognostic (7.46e-2)" "unprognostic (3.16e-1)" "unprognostic (6.86e-2)" "unprognostic (1.03e-2)" "unprognostic (3.17e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.63e-4)" 7.2 8.9 6.1 8.8 6.3 10.0 7.2 6.0 6.6 7.6 6.5 8.9 8.9 7.4 8.5 15.5 7.3 6.3 9.0 5.9 6.4 10.8 11.0 7.2 11.3 6.4 6.3 9.6 7.4 7.1 7.0 9.0 6.3 7.8 10.5 2.3 7.0 6.6 7.5 12.2 9.1 7.0 6.3 11.2 7.9 4.1 6.6 10.9 6.3 7.3 13.5 10.2 9.4 6.7 36.9 32.4 12.5 18.3 17.9 11.9 21.3 14.8 19.8 28.0 27.2 17.8 30.0 24.1 22.7 14.0 33.0 26.9 29.1 28.2 21.0 19.7 22.1 29.4 31.6 18.3 11.5 18.3 26.6 11.8 22.6 39.6 14.2 13.2 22.6 25.3 15.4 15.9 21.2 35.7 24.9 23.8 25.0 17.4 38.6 21.8 20.8 26.4 15.2 18.1 11.6 12.7 28.0 33.4 14.7 28.5 26.4 14.1 13.1 16.6 23.9 33.7 19.6 16.4 22.9 19.9 17.7 30.9 20.1 16.2 11.5 13.1 10.2 14.4 8.6 8.2 9.6 10.2 13.7 8.5 8.5 8.4 4.1 42.0 13.4 7.4 11.6 10.1 6.1 6.3 6.0 6.6 5.9 6.4 6.4 6.3 6.3 6.3 6.6 6.7 6.1 3.2 11.8 1.6 12.7 12.9 12.5 20.1 6.8 3.6 7.2 7.1 5.9 15.7 14.9 11.0 0.0 52.7 7.1 17.9 15.6 31.5 0.3 6.0 5.7 11.5 6.1 31.5 0.8 15.1 35.3 7.6 10.2 9.7 8.8 13.1 10.4 11.4 24.2 6.7 0.7 10.1 10.2 10.9 11.1 1.1 5.9 12.0 0.0 1.9 21.7 5.2 16.5 1.0 1.9 20.5 19.1 8.6 9.8 10.5 16.6 21.6 11.8 2.1 19.7 4.4 6.9 1.4 10.6 13.8 12.6 47.6 11.6 12.4 13.7 13.2 APPL1 APPL ENSG00000157500 "Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1" Q9UKG1 3 57227726-57278105 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 28.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011138 Approved Approved "Vesicles,Plasma membrane,Actin filaments,Cytosol" NA No 10000 "Cluster 37: B-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "Vesicles, Plasma membrane" "Actin filaments, Cytosol" "HPA011138: AB_1844959" "unprognostic (1.39e-1)" "unprognostic (3.45e-2)" "unprognostic (1.06e-2)" "unprognostic (2.01e-1)" "unprognostic (3.68e-2)" "unprognostic (2.31e-3)" "unprognostic (1.30e-3)" "unprognostic (1.81e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-2)" "unprognostic (9.05e-3)" "unprognostic (5.55e-2)" "prognostic favorable (7.26e-5)" "unprognostic (3.99e-2)" "unprognostic (8.76e-2)" "unprognostic (1.12e-2)" "unprognostic (1.55e-1)" 15.6 11.6 9.5 14.8 9.7 15.1 18.9 12.9 11.3 17.1 6.8 14.2 12.6 17.1 10.6 16.9 11.7 13.0 24.7 9.7 11.3 16.5 12.9 13.6 16.7 9.8 10.1 22.7 29.6 25.1 7.8 14.3 10.1 15.0 14.0 13.5 15.2 14.4 44.2 20.1 14.6 15.3 10.4 15.8 15.2 8.0 10.2 18.9 19.8 26.6 19.6 13.4 11.9 10.7 30.2 12.9 12.2 45.4 21.2 29.7 26.2 15.5 9.5 15.4 17.8 14.9 17.5 47.3 6.2 24.6 24.7 5.9 33.7 27.3 26.6 36.1 15.0 27.6 19.5 16.1 22.7 59.6 19.1 21.8 24.3 19.3 21.3 31.3 25.3 30.2 9.0 30.0 17.8 10.4 48.7 15.4 19.5 21.6 21.7 1.7 49.1 26.1 27.7 16.7 12.5 26.5 21.1 32.3 21.0 16.7 15.7 39.6 23.4 25.1 17.5 37.4 29.9 27.0 41.8 33.2 27.4 29.1 17.1 2.0 5.3 3.8 3.7 4.5 4.9 17.9 3.8 3.3 10.9 28.3 3.3 2.5 1.4 7.4 3.6 18.0 1.9 2.7 9.5 9.7 12.9 11.3 9.7 11.3 9.8 10.1 10.1 10.4 10.2 10.7 82.9 51.3 45.5 19.6 106.6 52.9 47.3 46.9 83.6 40.5 67.2 92.8 100.1 47.1 47.4 42.3 31.3 46.9 70.9 29.0 58.7 58.6 42.5 35.4 92.8 66.2 45.6 20.0 49.7 60.3 44.7 68.6 40.2 59.4 23.4 60.8 40.0 44.1 52.2 52.2 50.4 36.2 42.7 68.6 50.6 22.1 73.0 71.0 19.6 33.7 87.8 56.6 56.7 43.2 62.2 51.7 25.5 76.0 62.8 38.7 41.0 58.8 18.1 55.4 52.6 94.3 61.2 64.9 44.2 105.7 69.6 28.0 45.4 73.7 49.1 25.8 ARCN1 COPD ENSG00000095139 "Archain 1" P48444 11 118572390-118603033 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037573, HPA044874" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 140000 "Cluster 18: Basophils - Vesicular transport" "Cluster 29: Non-specific - Vesicular transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Golgi apparatus, Cytosol" "HPA037573: AB_10696938, HPA044874: AB_2679126" "unprognostic (1.46e-2)" "unprognostic (4.97e-2)" "unprognostic (1.66e-1)" "unprognostic (3.20e-1)" "unprognostic (9.99e-2)" "unprognostic (2.30e-2)" "prognostic unfavorable (2.97e-5)" "unprognostic (3.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-3)" "unprognostic (9.39e-2)" "unprognostic (3.56e-2)" "unprognostic (7.99e-2)" "unprognostic (9.20e-2)" "unprognostic (4.14e-3)" "unprognostic (5.56e-3)" 75.4 67.7 47.5 53.8 51.0 30.4 67.5 52.0 60.5 78.0 61.2 65.0 59.2 69.2 111.1 72.5 60.5 51.6 75.6 46.8 50.9 58.3 91.6 62.6 53.2 51.2 51.3 65.5 119.7 61.9 88.7 54.7 51.1 68.8 67.1 39.2 79.6 64.5 51.1 60.9 64.9 71.0 50.0 57.9 71.8 46.2 50.5 58.8 65.2 55.0 62.2 66.4 60.9 57.2 90.9 72.6 135.3 98.9 174.0 172.7 66.6 244.8 208.5 102.4 120.7 239.4 116.6 96.4 199.7 275.7 148.0 123.7 160.5 139.5 151.5 128.0 66.3 211.6 56.7 151.4 197.1 140.4 121.8 157.8 117.6 175.0 168.7 149.3 162.2 95.0 106.8 139.2 201.3 157.0 123.2 130.8 85.3 207.7 92.4 107.9 134.2 147.4 137.3 107.0 88.3 86.6 130.2 129.0 70.1 132.5 155.9 111.4 144.0 129.4 65.1 118.4 109.5 79.9 78.5 147.6 74.3 122.6 161.4 118.1 49.8 50.7 52.7 59.8 69.0 39.5 51.7 51.3 54.0 35.4 48.0 44.7 41.5 64.5 64.5 44.9 53.9 55.8 47.5 51.0 52.0 60.5 46.8 50.9 51.2 51.3 51.1 50.0 50.5 57.2 43.6 35.3 47.9 12.4 32.2 31.6 38.5 31.5 23.9 22.4 39.4 27.9 46.5 24.3 41.9 31.3 4.2 17.2 45.6 68.4 9.8 34.3 11.1 38.4 72.2 43.1 40.2 14.9 15.4 37.8 36.1 44.9 39.3 50.4 39.3 31.9 31.4 55.7 30.3 18.5 17.7 80.2 22.4 36.0 37.6 8.5 48.1 35.3 23.2 11.2 49.0 17.3 26.8 17.1 20.2 46.9 35.8 41.3 68.3 51.5 56.2 30.5 46.2 13.6 19.7 52.7 45.7 44.8 47.6 30.4 34.7 30.2 38.4 43.9 42.6 51.6 ARFIP1 HSU52521 ENSG00000164144 "ADP ribosylation factor interacting protein 1" P53367 4 152779937-152918463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005080, HPA037375, HPA063759" Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Vesicles" Nucleoplasm "CAB005080: AB_2058797, HPA037375: AB_2675440, HPA063759: AB_2685114" "unprognostic (1.06e-1)" "unprognostic (1.19e-1)" "prognostic favorable (5.75e-5)" "unprognostic (1.49e-3)" "unprognostic (4.32e-1)" "unprognostic (1.24e-1)" "unprognostic (3.54e-2)" "unprognostic (5.34e-1)" "unprognostic (1.03e-2)" "unprognostic (3.56e-1)" "unprognostic (3.60e-2)" "unprognostic (1.82e-2)" "prognostic favorable (2.83e-10)" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "unprognostic (7.02e-2)" "unprognostic (4.22e-3)" 16.8 14.8 7.9 15.8 8.7 3.7 23.4 9.9 10.8 22.5 9.9 28.1 23.2 21.7 20.5 20.9 18.5 19.9 10.2 7.3 9.3 19.8 15.4 16.8 15.1 9.3 8.0 17.6 10.5 22.4 10.5 18.0 9.5 21.1 27.8 20.2 13.7 17.2 6.6 17.3 21.3 19.8 9.4 18.3 22.7 12.1 8.3 12.0 20.1 10.4 14.8 23.5 15.2 11.4 25.8 18.4 25.1 25.7 37.2 37.9 30.6 29.5 40.5 28.7 26.9 21.3 51.3 20.6 9.9 40.5 22.7 18.1 26.3 29.1 35.3 16.9 16.2 20.0 18.0 20.5 26.1 38.2 41.7 26.6 30.9 24.8 23.8 30.7 26.4 11.8 23.5 43.3 39.8 28.6 22.7 19.8 21.8 29.9 18.5 12.6 14.7 19.2 50.7 32.1 32.8 26.0 22.1 40.7 30.2 23.5 37.7 19.6 17.3 27.8 20.1 26.8 21.4 48.2 42.8 28.1 35.3 38.2 40.0 31.5 27.3 42.2 14.5 31.1 14.6 19.0 11.2 12.2 24.8 17.7 8.7 11.8 81.6 29.1 30.7 3.1 18.5 18.7 7.9 8.7 9.9 10.8 7.3 9.3 9.3 8.0 9.5 9.4 8.3 11.4 28.5 6.4 31.8 40.5 20.3 29.6 18.4 30.7 34.1 17.2 26.2 19.7 10.2 20.0 29.1 38.6 0.0 28.6 15.6 40.9 27.4 27.4 46.3 42.2 33.0 23.8 38.9 12.0 44.5 18.3 27.0 28.8 40.2 50.7 22.8 14.2 17.2 19.8 22.1 18.5 42.8 39.1 34.6 23.8 18.0 21.6 22.4 24.5 21.4 89.9 19.5 35.9 23.7 76.4 75.6 24.4 28.2 21.8 11.8 23.6 23.8 34.2 31.9 24.2 32.9 20.6 27.8 31.7 29.5 31.9 34.0 43.9 17.7 89.2 31.7 30.3 ARHGAP30 FLJ00267 ENSG00000186517 "Rho GTPase activating protein 30" Q7Z6I6 1 161046946-161069970 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 57.6;lymphoid tissue: 77.0" "Cell type enhanced" "Detected in many" "B-cells: 71.6;dendritic cells: 103.4;Kupffer cells: 77.8;Macrophages: 79.1;monocytes: 133.0;NK-cells: 268.8;T-cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 118.2;HL-60: 92.5;HMC-1: 123.4;Karpas-707: 93.1;MOLT-4: 75.8;THP-1: 90.9;U-266/70: 138.6;U-266/84: 97.7;U-698: 97.9;U-937: 72.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036300 Enhanced Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA036300: AB_10601117" "unprognostic (7.31e-2)" "unprognostic (8.83e-3)" "unprognostic (7.46e-3)" "unprognostic (1.77e-3)" "unprognostic (7.41e-2)" "unprognostic (1.68e-3)" "unprognostic (3.05e-1)" "unprognostic (6.78e-3)" "unprognostic (1.94e-2)" "unprognostic (3.89e-2)" "unprognostic (7.91e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (9.78e-4)" "unprognostic (1.18e-1)" "unprognostic (1.08e-2)" "unprognostic (6.64e-2)" "unprognostic (2.65e-2)" 12.1 4.9 3.1 55.9 3.6 57.6 5.3 3.7 4.3 3.4 3.3 8.1 9.5 2.9 2.8 14.1 4.5 10.2 2.8 2.9 3.6 3.4 6.6 25.2 77.0 6.1 4.5 2.0 2.4 1.4 1.8 7.0 5.4 3.4 8.4 0.6 6.4 2.3 2.6 19.8 23.9 8.0 5.0 75.5 11.6 2.3 6.3 63.7 2.9 2.7 61.2 13.8 6.5 6.8 0.8 0.1 0.2 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.3 1.2 118.2 0.6 0.0 0.1 2.3 0.0 0.0 0.2 55.3 0.2 39.7 0.2 0.0 0.0 92.5 123.4 0.0 1.2 0.1 0.0 0.1 0.0 56.8 0.3 93.1 0.0 1.0 75.8 21.3 0.1 0.7 0.1 46.8 0.6 1.6 0.0 1.0 0.7 0.3 0.2 0.7 0.2 0.7 0.8 90.9 0.9 0.1 0.7 0.2 0.5 138.6 97.7 97.9 0.4 72.3 0.1 7.1 29.6 33.1 32.9 32.2 25.1 11.9 21.9 27.1 21.8 12.6 17.9 25.0 48.5 19.3 46.4 15.0 23.8 33.5 3.1 3.6 3.7 4.3 2.9 3.6 6.1 4.5 5.4 5.0 6.3 6.8 1.5 3.2 20.5 0.3 71.6 5.6 3.3 6.8 0.0 0.5 5.2 2.9 1.3 2.8 13.8 0.0 4.2 0.6 103.4 0.5 0.0 3.4 2.2 6.6 1.2 2.3 0.0 14.5 0.3 6.0 1.9 1.9 3.1 13.7 68.3 0.0 6.1 1.7 55.5 0.0 0.3 0.4 8.2 77.8 44.6 0.7 0.3 79.1 5.4 14.0 133.0 0.1 268.8 0.5 1.2 12.5 0.2 0.0 49.8 5.4 0.0 0.5 15.3 3.0 0.0 1.0 1.9 0.1 0.1 9.9 24.6 4.5 105.1 0.2 0.5 16.7 ARL14EP "ARF7EP, C11orf46, FLJ38968" ENSG00000152219 "ADP ribosylation factor like GTPase 14 effector protein" Q8N8R7 11 30323104-30338223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 130.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039634, HPA048127" Approved Supported "Nucleoplasm,Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Vesicles, Focal adhesion sites, Cytosol" Nucleoplasm "HPA039634: AB_2676606, HPA048127: AB_2680277" "prognostic favorable (2.50e-5)" "unprognostic (8.93e-2)" "unprognostic (6.19e-3)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (5.26e-4)" "unprognostic (2.50e-2)" "unprognostic (6.50e-3)" "unprognostic (5.76e-2)" "unprognostic (8.86e-2)" "unprognostic (1.04e-1)" "unprognostic (8.57e-3)" "unprognostic (1.60e-1)" "unprognostic (3.47e-1)" "unprognostic (4.50e-2)" "prognostic favorable (7.49e-4)" 13.9 22.5 13.5 13.2 15.6 8.0 20.0 15.9 17.3 17.0 14.9 11.8 9.5 18.9 23.2 11.6 16.4 13.1 22.9 15.7 14.2 17.4 19.7 10.9 22.5 12.4 13.3 20.5 12.9 26.1 12.0 11.5 12.1 19.7 10.8 15.9 19.1 19.9 20.6 12.6 9.7 14.5 13.9 20.8 15.7 14.6 13.3 15.6 24.7 20.8 21.4 14.5 8.1 13.8 10.8 15.4 16.9 14.8 27.1 29.2 8.5 20.8 26.0 18.4 20.2 8.5 4.1 43.8 13.9 15.0 20.5 17.8 24.8 17.5 25.9 35.2 30.7 13.3 12.0 15.0 42.6 24.0 14.7 30.5 34.7 8.7 32.8 26.7 20.6 17.9 21.4 23.2 32.5 10.4 21.9 19.6 19.6 24.1 21.3 18.8 41.2 18.0 24.7 14.8 19.2 20.4 16.2 21.4 25.8 15.0 22.8 13.4 18.1 20.8 11.2 41.7 20.1 36.0 21.9 28.5 20.0 14.8 20.4 12.7 19.2 6.4 23.3 20.0 55.5 35.9 28.2 25.9 26.3 28.9 25.7 25.0 3.5 52.9 15.5 18.9 20.3 23.1 13.5 15.6 15.9 17.3 15.7 14.2 12.4 13.3 12.1 13.9 13.3 13.8 27.3 28.9 33.6 14.4 39.7 12.4 46.6 35.1 8.0 34.0 19.9 30.4 68.1 24.3 23.8 25.8 14.6 19.1 29.2 5.9 76.3 27.3 130.1 25.8 41.0 29.2 14.5 13.2 31.1 22.5 12.7 33.4 12.8 19.0 27.8 33.5 15.4 29.8 25.7 32.0 26.4 11.7 32.6 27.1 29.3 66.3 27.4 28.4 26.6 18.7 45.4 36.1 38.1 27.6 19.9 21.9 8.4 25.2 25.4 46.0 9.4 42.1 27.5 32.4 13.1 33.1 29.8 111.4 37.6 13.8 11.1 11.1 29.6 33.0 12.6 28.4 ARPC1B "ARC41, p40-ARC, p41-ARC" ENSG00000130429 "Actin related protein 2/3 complex subunit 1B" O15143 7 99374249-99394816 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 317.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 948.7;Hofbauer cells: 1088.1;Kupffer cells: 1035.5;monocytes: 1029.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 899.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004832 Enhanced Supported Vesicles,Cytosol NA NA 13000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 51: Myeloid cells - Hemostasis" "Vesicles, Cytosol" "HPA004832: AB_1845044" "unprognostic (5.94e-2)" "unprognostic (2.40e-2)" "unprognostic (2.84e-3)" "unprognostic (2.47e-2)" "unprognostic (1.43e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (2.57e-4)" "unprognostic (4.37e-2)" "unprognostic (7.76e-2)" "unprognostic (1.02e-2)" "unprognostic (1.56e-1)" "unprognostic (4.86e-1)" "prognostic unfavorable (1.62e-6)" "unprognostic (1.18e-1)" "unprognostic (1.87e-2)" "unprognostic (1.24e-1)" "unprognostic (7.27e-2)" 132.2 71.6 19.6 173.3 20.4 209.8 99.1 20.5 25.9 71.7 23.9 104.4 106.6 71.0 14.2 51.6 73.9 48.9 70.1 18.2 21.7 84.4 81.7 169.5 202.1 28.9 23.5 30.1 51.4 14.3 52.4 66.4 26.8 67.4 32.5 1.1 72.4 30.1 18.6 43.2 160.2 39.4 27.3 317.3 66.2 20.4 33.3 62.2 90.1 19.5 95.5 85.1 57.5 28.4 124.3 219.3 16.1 47.5 62.9 225.0 167.9 165.8 170.5 68.7 60.5 146.3 477.8 215.4 308.2 188.5 146.9 93.1 22.4 152.5 27.5 175.5 59.9 157.0 61.6 98.4 179.7 159.5 515.8 125.7 77.3 96.2 94.3 134.6 181.5 113.3 177.9 508.0 100.2 574.5 158.8 332.5 59.6 148.9 435.5 139.5 14.6 536.2 141.2 59.7 13.2 42.1 116.4 506.3 899.5 54.4 119.7 322.4 262.0 190.1 155.8 339.0 216.6 91.4 190.1 263.5 189.9 411.0 350.4 1026.1 2400.1 1973.2 770.3 2458.8 723.9 786.7 883.0 857.2 2054.4 699.1 510.2 680.0 1963.4 633.5 2382.6 1172.9 1315.9 4198.2 19.6 20.4 20.5 25.9 18.2 21.7 28.9 23.5 26.8 27.3 33.3 28.4 182.2 41.7 86.6 1.0 279.2 60.5 141.3 587.9 58.1 9.6 50.8 34.3 9.1 107.2 260.2 130.6 8.4 588.4 416.3 264.9 25.4 407.1 3.2 37.7 37.2 265.5 112.7 84.9 3.2 414.5 948.7 99.7 62.7 41.3 192.2 31.0 226.3 54.5 1088.1 1.7 2.3 97.6 203.4 1035.5 422.8 8.4 37.3 789.1 179.7 28.1 1029.7 21.4 498.5 0.5 1.6 405.1 268.7 18.0 154.0 132.4 516.0 110.9 214.0 14.7 92.1 29.5 238.5 2.7 15.5 26.3 37.1 303.2 324.4 20.4 161.1 187.6 ARRDC4 FLJ36045 ENSG00000140450 "Arrestin domain containing 4" Q8NCT1 15 97960703-97973833 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 82.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 105.7;Paneth cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 1.1;classical monocyte: 2.5;eosinophil: 1.5;intermediate monocyte: 1.7;myeloid DC: 1.1;neutrophil: 1.4" "Group enriched" "Detected in many" 8 "dendritic cells: 1.1;granulocytes: 1.5;monocytes: 2.5" "Cell line enhanced" "Detected in many" "BJ: 103.2;HSkMC: 55.8;hTCEpi: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039934, HPA042109" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Vesicles "HPA039934: , HPA042109: AB_10795606" "unprognostic (2.13e-1)" "unprognostic (1.10e-1)" "unprognostic (2.32e-1)" "unprognostic (5.60e-3)" "unprognostic (4.49e-3)" "unprognostic (8.23e-2)" "unprognostic (1.16e-2)" "unprognostic (2.78e-1)" "unprognostic (7.65e-2)" "unprognostic (1.10e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (2.02e-3)" "unprognostic (2.90e-2)" "unprognostic (1.65e-1)" "unprognostic (3.04e-2)" "unprognostic (6.77e-2)" 12.5 12.2 21.6 16.5 24.6 11.5 19.8 24.1 22.4 16.2 16.9 43.9 15.8 14.6 15.6 10.0 14.5 17.2 12.1 30.5 39.1 25.1 30.2 19.8 7.5 76.6 24.1 7.3 34.7 6.3 8.9 18.3 73.9 10.9 23.0 4.5 8.1 16.4 14.8 35.5 22.6 18.1 45.9 8.0 26.9 14.7 20.5 5.7 17.3 9.6 5.1 14.9 10.8 82.8 5.8 0.2 0.8 15.0 6.6 47.7 0.0 103.2 45.8 13.5 6.0 6.2 3.6 0.0 14.2 4.8 1.2 6.0 3.7 36.0 21.6 0.0 9.6 10.1 1.9 4.1 2.6 7.0 15.2 55.8 86.9 15.4 17.9 18.8 0.7 2.9 14.4 0.0 4.9 19.2 1.2 5.8 3.0 17.4 2.1 0.1 0.9 0.2 26.3 12.7 5.0 8.8 15.7 5.7 29.5 3.1 2.1 10.6 0.1 4.0 2.9 21.2 5.0 0.0 0.0 0.2 8.7 1.2 10.6 1.1 2.5 1.5 0.0 1.7 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.4 21.6 24.6 24.1 22.4 30.5 39.1 76.6 24.1 73.9 45.9 20.5 82.8 5.7 3.2 10.4 19.9 4.0 25.4 3.1 11.0 23.9 1.6 14.4 8.3 12.9 8.6 9.4 22.0 6.2 0.3 1.4 105.7 7.9 2.7 4.5 21.5 17.6 5.9 38.3 4.4 8.1 8.2 0.2 12.3 15.8 18.0 23.5 1.4 6.4 17.1 21.5 0.0 6.0 29.5 10.2 23.9 10.5 10.9 5.0 19.7 24.9 3.7 13.4 0.7 3.1 38.7 3.4 12.0 82.4 8.2 0.2 12.2 30.2 3.1 15.6 3.5 0.0 7.8 12.5 2.0 12.6 11.8 31.1 0.7 1.3 17.5 31.3 12.2 ASAP3 "CENTB6, DDEFL1, FLJ20199, UPLC1" ENSG00000088280 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 3" Q8TDY4 1 23428563-23484568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 35.9;Extravillous trophoblasts: 43.3;Granulosa cells: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 31.8;ASC TERT1: 29.9;HSkMC: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020537, HPA020546" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Vesicles Nucleoplasm "HPA020537: AB_2670467, HPA020546: AB_2670470" "unprognostic (2.51e-1)" "unprognostic (2.70e-2)" "unprognostic (4.35e-3)" "prognostic unfavorable (5.56e-4)" "unprognostic (3.87e-1)" "unprognostic (2.24e-2)" "unprognostic (1.19e-3)" "prognostic favorable (2.80e-4)" "unprognostic (1.88e-2)" "prognostic unfavorable (8.30e-4)" "unprognostic (2.24e-1)" "unprognostic (1.18e-1)" "prognostic favorable (5.12e-5)" "unprognostic (3.39e-3)" "unprognostic (3.92e-2)" "unprognostic (2.02e-2)" "unprognostic (7.27e-2)" 24.1 39.1 11.5 3.2 11.6 0.1 21.9 12.5 12.4 32.6 10.0 18.4 1.6 18.6 4.2 32.3 24.3 5.1 30.1 10.5 11.2 21.4 19.8 15.9 1.6 14.5 12.7 58.3 22.2 11.7 18.6 8.0 13.2 31.0 5.2 3.0 38.0 8.0 42.9 52.9 11.0 5.9 12.7 5.0 25.4 18.2 13.4 1.0 29.0 11.7 4.2 21.3 33.4 12.1 1.8 1.8 17.6 11.6 31.8 29.9 21.6 3.2 3.8 4.9 6.3 1.3 0.1 9.2 3.7 6.3 2.9 8.4 12.2 2.9 2.8 0.4 1.6 0.5 4.8 11.8 17.1 0.0 0.9 38.4 4.4 7.9 7.1 14.6 3.9 1.3 6.4 0.0 3.1 3.9 1.3 0.1 3.0 5.0 4.2 4.9 1.9 0.0 3.4 3.7 0.6 6.0 14.1 3.5 3.5 8.7 13.2 0.1 1.4 2.1 5.2 5.9 0.2 3.9 4.2 1.1 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 11.5 11.6 12.5 12.4 10.5 11.2 14.5 12.7 13.2 12.7 13.4 12.1 4.5 9.6 6.7 35.9 0.3 2.0 1.5 2.0 2.8 1.1 6.3 3.7 15.5 0.0 4.1 3.7 0.0 2.1 0.0 6.7 3.9 5.8 5.1 2.4 7.3 6.6 1.2 0.0 7.6 6.1 43.3 12.2 10.2 4.4 1.3 28.3 3.9 4.0 1.8 0.0 4.9 8.5 2.0 0.0 1.3 8.1 12.5 0.4 0.0 7.5 0.1 8.3 0.0 18.1 4.2 2.5 2.1 13.5 0.2 2.4 0.8 5.4 4.3 0.6 0.0 2.0 3.4 8.2 11.8 3.7 4.3 1.4 0.2 15.9 5.2 2.1 ASGR1 CLEC4H1 ENSG00000141505 "Asialoglycoprotein receptor 1" P07306 17 7173431-7179564 "Predicted intracellular proteins, Predicted secreted proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 41 "liver: 1092.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 1107.9" "Cancer enriched" "Detected in many" 90 "liver cancer: 131.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 115.2;intermediate monocyte: 55.5;myeloid DC: 41.2" "Group enriched" "Detected in many" 8 "dendritic cells: 41.2;monocytes: 115.2" "Cell line enriched" "Detected in some" 29 "Hep G2: 493.2" "Region enriched" "Detected in all" 9 "cerebellum: 44.1" "Not detected" "Not detected" "HPA011954, HPA012852" Enhanced Supported "Vesicles,Cell Junctions" "Secreted to blood" NA NA 10000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Cell Junctions" "HPA011954: AB_1845079, HPA012852: AB_1845080" "unprognostic (3.56e-3)" "unprognostic (3.57e-1)" "unprognostic (8.76e-2)" "unprognostic (4.05e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-2)" "unprognostic (5.37e-2)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (8.55e-5)" "unprognostic (1.55e-1)" "unprognostic (8.33e-11)" "unprognostic (1.45e-1)" "unprognostic (2.00e-1)" "unprognostic (1.73e-3)" "unprognostic (4.46e-3)" 2.6 1.5 7.7 3.7 7.8 2.5 1.8 17.0 10.9 1.6 7.0 1.2 2.2 1.3 0.6 1.7 1.8 2.9 1.1 7.9 7.6 1.4 1092.3 3.9 1.3 8.0 8.2 1.1 0.9 7.0 2.9 0.5 8.3 1.7 0.5 4.8 0.9 0.3 1.5 4.4 1.4 1.3 6.0 4.8 1.4 26.5 7.8 0.4 5.8 0.4 0.3 1.7 1.5 8.7 0.3 0.7 9.2 4.2 0.0 0.2 0.8 0.8 0.9 0.9 1.6 16.8 0.5 0.3 1.1 0.2 0.4 0.2 0.3 0.2 0.4 0.3 0.8 1.2 1.4 493.2 0.1 0.8 1.7 1.2 0.2 0.5 0.1 0.6 8.4 7.4 1.1 0.6 0.5 0.4 0.7 1.2 1.7 0.2 0.4 0.9 3.5 0.2 0.1 0.7 0.6 3.5 0.7 0.3 0.6 1.5 0.5 0.2 1.2 0.9 3.4 0.7 0.4 0.2 0.3 0.5 0.6 0.4 0.3 10.0 115.2 0.4 0.2 55.5 1.1 0.5 0.2 0.2 41.2 0.5 0.3 0.4 3.3 0.5 14.9 1.8 0.3 36.7 7.7 7.8 17.0 10.9 7.9 7.6 8.0 8.2 8.3 6.0 7.8 8.7 6.0 0.0 4.7 2.9 2.6 3.2 1.7 2.0 3.4 37.8 5.6 6.0 1.5 55.8 2.0 3.7 160.6 3.6 2.9 1.4 3.9 0.9 235.4 4.2 3.6 13.2 15.6 16.8 4.6 0.2 3.7 1.9 3.6 16.5 0.0 5.1 27.5 1107.9 39.9 15.2 4.8 2.3 2.0 97.4 11.9 115.8 2.5 52.6 0.0 1.9 77.2 3.6 0.0 2.0 0.6 0.3 1.3 1.2 0.0 0.9 0.2 6.8 1.6 42.3 0.0 0.8 1.9 6.5 9.7 9.9 4.8 12.4 1.4 1.6 1.3 2.4 ASIP "AGTIL, ASP" ENSG00000101440 "Agouti signaling protein" P42127 20 34194569-34269344 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 14.8;heart muscle: 28.0;ovary: 41.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.4;dendritic cells: 44.1;Hofbauer cells: 15.1;Leydig cells: 12.5;Peritubular cells: 10.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 356 "plasmacytoid DC: 134.8" "Lineage enriched" "Detected in single" 356 "dendritic cells: 134.8" "Cell line enhanced" "Detected in some" "CACO-2: 3.2;HSkMC: 2.4;SK-MEL-30: 1.9;U-698: 1.9" "Not detected" "Not detected" HPA048636 Uncertain Supported Vesicles "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA048636: AB_2680471" "unprognostic (4.81e-2)" "unprognostic (7.46e-2)" "unprognostic (1.97e-3)" "unprognostic (3.26e-2)" "unprognostic (2.24e-1)" "unprognostic (3.07e-2)" "unprognostic (5.13e-2)" "unprognostic (4.57e-2)" "unprognostic (4.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (5.53e-6)" "unprognostic (1.02e-1)" "unprognostic (3.09e-1)" "unprognostic (1.27e-1)" "unprognostic (1.33e-1)" 1.4 0.6 0.2 0.0 0.5 0.3 2.4 0.1 0.4 4.2 0.0 0.5 0.0 2.0 14.8 0.1 4.0 0.1 28.0 0.1 0.1 0.9 1.3 0.3 0.4 0.2 0.1 41.7 0.1 0.0 0.6 0.2 0.6 1.5 0.0 0.3 0.7 0.2 0.9 5.7 0.8 0.0 0.0 0.3 0.3 1.5 0.2 0.2 0.3 1.2 0.5 0.5 1.1 0.3 0.0 1.1 0.4 0.4 0.2 0.7 0.1 0.1 0.0 0.0 0.0 3.2 0.0 1.2 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.7 1.7 0.3 0.5 0.0 0.0 0.4 2.4 0.0 0.0 0.0 0.1 0.0 0.7 0.6 0.9 0.0 0.3 0.2 1.7 0.0 0.1 0.6 0.3 0.3 1.4 0.0 0.1 0.2 0.2 0.0 0.2 1.9 0.5 0.3 0.2 0.3 0.5 0.5 0.0 0.3 0.4 0.4 1.9 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 134.8 0.0 0.6 0.2 0.5 0.1 0.4 0.1 0.1 0.2 0.1 0.6 0.0 0.2 0.3 0.4 0.0 0.6 1.3 0.8 2.5 0.0 0.0 0.0 0.0 0.3 0.5 27.4 0.0 0.0 0.0 0.0 0.2 44.1 0.0 1.9 0.0 1.1 0.3 9.2 1.2 0.0 0.0 2.1 0.0 0.2 5.6 0.0 0.4 0.0 0.2 2.5 5.8 15.1 0.0 1.8 0.0 0.0 0.8 7.0 1.7 12.5 2.1 1.8 1.0 0.3 0.0 0.0 2.5 2.5 0.1 0.0 10.5 0.0 0.1 0.0 8.3 0.0 0.0 6.6 0.1 0.6 1.7 1.9 0.2 3.1 0.8 0.6 1.0 0.0 0.1 ASPSCR1 "ASPL, ASPS, TUG, UBXD9, UBXN9" ENSG00000169696 "ASPSCR1 tether for SLC2A4, UBX domain containing" Q9BZE9 17 81976807-82017406 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 222.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "Hep G2: 298.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026749 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Vesicles, Plasma membrane" "HPA026749: AB_1845114" "unprognostic (5.01e-2)" "unprognostic (1.19e-3)" "unprognostic (7.61e-2)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "prognostic favorable (8.55e-4)" "unprognostic (2.02e-1)" "unprognostic (2.07e-2)" "unprognostic (3.43e-1)" "unprognostic (1.71e-3)" "prognostic favorable (2.67e-4)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (3.16e-2)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (1.01e-2)" 16.5 20.4 16.6 8.4 17.0 15.0 16.9 16.5 20.4 16.2 17.7 16.0 13.6 15.6 7.9 16.8 14.0 7.7 26.1 16.2 15.5 27.3 57.9 17.3 12.2 20.1 16.6 13.4 22.8 14.8 30.6 12.9 18.3 21.6 4.6 5.7 18.3 6.7 44.3 20.5 18.1 5.2 14.7 20.7 22.7 30.0 17.2 8.3 25.9 5.8 6.4 16.0 14.2 21.5 19.3 33.3 13.0 17.9 7.5 9.3 55.4 17.7 12.6 19.3 19.5 20.3 21.3 19.2 18.1 12.4 16.3 9.8 12.0 13.1 6.2 12.9 41.0 21.4 28.7 298.1 25.5 19.1 29.9 10.9 13.9 9.5 6.6 10.0 19.5 16.0 22.0 25.0 11.6 65.0 16.9 41.8 15.5 32.8 23.5 19.2 18.7 39.4 18.0 17.0 32.4 34.8 14.6 42.2 35.2 12.3 27.2 41.4 16.6 35.7 24.5 26.4 22.8 20.2 12.5 21.6 19.2 19.3 21.3 24.0 11.7 8.6 6.6 8.0 3.7 9.0 10.0 8.8 14.7 9.0 7.7 5.8 2.7 8.0 10.4 9.3 5.3 5.6 16.6 17.0 16.5 20.4 16.2 15.5 20.1 16.6 18.3 14.7 17.2 21.5 13.9 9.6 44.7 19.9 24.1 13.4 23.7 24.4 23.3 23.3 19.6 15.6 13.6 27.1 19.8 14.7 41.7 73.7 25.8 29.3 39.2 24.2 49.1 16.2 14.9 16.1 25.0 17.9 12.4 26.2 222.6 17.5 46.9 20.1 21.5 31.0 12.8 56.1 44.7 50.5 12.1 31.5 20.3 26.7 18.6 96.0 11.8 21.7 19.6 1.9 23.8 57.8 19.6 10.6 14.1 17.6 25.8 17.7 27.3 24.9 42.5 58.3 18.5 39.4 13.1 14.7 37.4 41.7 51.0 20.3 14.3 59.4 18.4 23.6 33.3 23.1 ATG12 "APG12, APG12L" ENSG00000145782 "Autophagy related 12" O94817 5 115828200-115841837 "Predicted intracellular proteins, Transporters" "Autophagy, Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013272, HPA068989" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "CAB013272: AB_2533272, HPA068989: " "unprognostic (2.48e-2)" "unprognostic (1.40e-1)" "unprognostic (2.38e-1)" "unprognostic (1.29e-1)" "unprognostic (1.22e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.36e-4)" "unprognostic (2.72e-2)" "unprognostic (2.87e-2)" "unprognostic (5.51e-2)" "unprognostic (9.36e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.54e-7)" "unprognostic (1.27e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (4.99e-4)" "unprognostic (5.11e-2)" 15.5 10.5 12.3 10.7 12.7 11.3 10.2 12.9 16.9 12.0 10.5 10.4 11.6 10.8 11.9 11.3 9.8 11.6 9.7 12.6 13.3 7.1 18.4 10.4 13.6 13.2 13.2 12.0 9.5 7.4 8.7 13.6 13.7 10.8 11.1 9.6 7.9 10.9 11.1 9.0 11.9 12.7 12.7 11.2 8.8 9.4 12.8 14.0 8.6 12.6 11.6 11.8 8.8 15.0 20.7 10.9 26.3 24.1 42.9 57.4 20.0 34.9 38.3 22.6 36.5 15.8 16.5 17.8 14.5 32.1 35.3 11.3 20.5 29.4 36.4 93.2 20.2 11.5 13.0 14.8 33.7 12.8 22.0 43.0 31.5 25.1 29.6 26.3 27.6 19.0 16.8 24.4 43.5 13.5 27.2 20.2 17.9 15.7 23.6 19.8 25.4 25.7 15.7 13.7 25.8 27.6 37.3 14.7 36.6 20.0 20.3 19.2 28.3 41.3 18.9 38.2 36.0 18.7 31.5 28.9 37.7 27.2 39.6 15.4 11.5 19.3 11.8 13.6 16.5 12.3 14.3 11.7 10.3 12.2 14.6 14.1 20.9 14.4 17.4 13.8 12.3 11.0 12.3 12.7 12.9 16.9 12.6 13.3 13.2 13.2 13.7 12.7 12.8 15.0 52.5 44.8 41.0 17.0 82.8 85.8 65.4 81.6 44.3 42.3 46.8 36.1 45.2 38.6 56.9 25.8 77.2 61.8 92.3 50.3 37.2 60.6 28.7 49.0 60.7 55.1 41.8 23.8 28.5 81.6 134.1 75.2 36.2 55.8 96.9 48.8 47.5 57.9 68.2 30.3 26.5 54.5 59.0 72.1 69.8 14.9 64.0 53.7 53.4 19.7 76.8 34.1 99.9 26.7 35.5 105.5 45.8 53.8 50.1 68.4 56.3 44.3 49.7 59.2 26.3 39.5 50.5 50.0 45.1 40.0 84.7 88.7 78.8 45.1 46.0 78.1 ATG2A KIAA0404 ENSG00000110046 "Autophagy related 2A" Q2TAZ0 11 64894546-64917211 "Predicted intracellular proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 16.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038715 Uncertain Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Vesicles Nucleoplasm "HPA038715: AB_10673474" "unprognostic (3.05e-2)" "unprognostic (2.33e-1)" "unprognostic (7.55e-2)" "unprognostic (1.18e-1)" "unprognostic (3.42e-1)" "unprognostic (9.23e-3)" "unprognostic (1.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.37e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (1.66e-2)" "prognostic favorable (4.79e-5)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (3.37e-1)" "unprognostic (1.15e-1)" 16.4 20.1 11.4 6.5 10.9 60.2 16.9 8.6 40.1 19.9 11.4 18.9 7.5 18.2 1.8 15.7 19.2 4.2 18.4 11.5 9.8 22.0 59.2 24.2 6.1 13.9 12.3 24.9 22.7 4.9 21.6 4.9 12.7 21.6 2.6 1.9 15.2 5.7 26.7 34.9 21.4 3.3 9.0 25.7 23.2 15.3 11.4 5.4 19.3 4.4 3.3 17.7 15.6 10.4 13.2 12.6 4.4 12.0 5.7 4.0 12.3 7.1 10.3 9.4 6.8 11.0 9.9 9.3 14.7 6.0 12.0 10.8 4.5 8.3 2.5 9.1 15.7 8.7 19.1 10.0 8.4 6.5 18.2 10.9 7.1 11.8 6.3 5.4 7.9 9.5 16.1 7.3 4.1 21.3 7.8 21.9 5.1 3.5 14.3 8.6 7.1 13.5 5.0 10.9 16.5 6.7 10.6 14.6 13.3 3.3 14.3 8.1 10.1 9.0 8.6 18.3 5.3 14.7 5.5 6.5 13.0 5.2 5.6 3.0 2.0 2.2 2.5 2.1 2.1 0.8 1.7 2.2 1.4 0.9 1.3 2.4 16.9 1.8 1.7 2.4 0.9 1.2 11.4 10.9 8.6 40.1 11.5 9.8 13.9 12.3 12.7 9.0 11.4 10.4 9.8 9.6 16.2 20.2 17.0 28.9 8.7 35.7 16.5 16.6 15.8 10.3 8.1 7.2 17.6 9.2 33.3 12.7 40.1 38.8 1.9 10.2 2.5 12.4 9.2 10.2 35.9 16.2 7.6 10.3 5.3 12.6 16.8 24.4 9.5 15.4 7.9 23.2 10.9 13.5 8.4 17.6 24.4 20.1 19.9 3.6 12.8 24.2 30.2 5.6 11.9 12.3 19.6 6.6 7.1 14.9 21.7 10.1 27.3 12.2 26.8 6.6 13.3 26.0 13.1 11.6 10.6 9.0 6.2 16.3 38.4 66.9 40.2 27.2 19.0 15.9 ATG9A "APG9L1, FLJ22169" ENSG00000198925 "Autophagy related 9A" Q7Z3C6 2 219219380-219229717 "Predicted membrane proteins, Transporters" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 83.8;Late spermatids: 105.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059551 Uncertain Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "HPA059551: AB_2684060" "unprognostic (1.53e-2)" "unprognostic (4.03e-1)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (4.80e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (2.18e-5)" "unprognostic (8.99e-3)" "unprognostic (2.07e-1)" "unprognostic (3.55e-3)" "unprognostic (4.67e-2)" "unprognostic (4.21e-1)" "unprognostic (2.23e-2)" "unprognostic (4.84e-2)" "unprognostic (3.15e-1)" "unprognostic (5.61e-2)" "unprognostic (1.95e-2)" 25.6 23.6 27.2 17.3 29.0 44.7 19.2 27.8 36.6 19.5 10.0 25.6 31.4 24.1 14.2 31.4 18.8 21.8 42.1 30.0 24.3 20.0 25.9 23.7 19.4 29.0 26.7 20.4 28.1 31.2 17.6 30.7 26.2 21.6 21.8 24.6 23.9 22.8 116.8 32.1 29.7 28.1 24.3 21.7 22.8 62.2 27.6 15.7 18.4 62.7 21.2 22.7 22.7 28.6 29.4 35.7 26.9 64.0 50.3 55.1 35.9 52.1 56.1 67.3 60.2 52.9 38.8 7.7 43.7 79.8 54.7 58.0 43.2 56.9 49.6 22.6 70.7 55.7 90.1 63.9 54.9 14.1 40.6 56.7 91.4 68.7 63.0 60.9 68.2 18.6 75.6 27.0 46.2 38.3 12.2 33.4 19.5 28.5 26.9 16.9 36.7 30.2 40.0 38.6 42.6 25.7 52.0 46.7 46.5 52.0 17.3 39.3 52.5 67.0 32.3 28.7 47.1 15.5 14.7 11.2 55.7 33.9 37.2 6.5 12.4 6.3 7.2 18.0 7.2 5.6 5.6 9.1 8.5 3.6 5.4 6.1 11.2 9.7 22.6 4.1 7.1 11.6 27.2 29.0 27.8 36.6 30.0 24.3 29.0 26.7 26.2 24.3 27.6 28.6 0.3 0.0 4.5 12.7 8.2 7.8 7.6 10.6 8.6 18.9 0.3 0.3 33.2 17.2 7.1 0.0 14.6 26.8 4.1 44.0 0.0 0.2 83.8 0.6 1.5 10.0 13.8 34.7 15.2 0.5 24.4 9.1 11.7 0.8 10.2 0.3 16.8 37.1 11.5 21.9 14.1 17.6 6.1 13.3 7.0 105.9 14.0 4.8 10.6 5.6 7.0 20.5 9.2 9.5 12.5 0.3 27.6 8.6 6.7 13.4 39.3 0.3 4.7 15.7 13.1 7.1 5.5 54.9 13.8 14.2 11.1 34.8 7.5 0.8 18.5 10.5 ATM "ATA, ATC, ATD, ATDC, TEL1, TELO1" ENSG00000149311 "ATM serine/threonine kinase" Q13315 11 108222832-108369102 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 210.6;NK-cells: 339.8;Oligodendrocytes: 217.6;Rod photoreceptor cells: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 78.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000102, HPA067142" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Vesicles "CAB000102: , HPA067142: AB_2685789" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.04e-1)" "unprognostic (2.36e-1)" "unprognostic (5.70e-2)" "unprognostic (2.86e-2)" "unprognostic (6.32e-3)" "unprognostic (1.05e-1)" "unprognostic (8.19e-2)" "unprognostic (1.63e-1)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (2.17e-3)" "unprognostic (3.10e-1)" "unprognostic (7.87e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-1)" 6.2 7.4 8.2 17.5 15.0 16.2 8.5 17.0 12.3 8.7 16.1 6.7 5.2 10.0 9.9 4.0 7.5 8.2 7.0 7.3 11.3 5.8 7.8 7.6 33.7 15.8 13.1 15.8 14.8 9.3 12.1 8.0 17.0 6.3 7.0 20.6 11.4 6.1 4.4 7.5 12.6 6.9 10.3 22.2 8.6 5.2 12.7 18.2 8.8 6.0 25.9 7.1 6.9 28.8 4.3 6.8 14.8 7.6 20.2 29.1 3.1 10.9 13.5 6.4 11.3 7.1 10.3 18.3 14.0 10.2 9.6 7.7 11.6 10.8 9.0 12.3 5.7 15.2 8.7 10.2 10.5 16.4 17.0 18.3 6.3 10.0 21.2 15.2 14.1 16.5 12.4 9.9 14.3 3.4 10.6 18.5 9.8 8.6 7.4 9.7 9.7 24.9 8.1 7.5 9.0 10.5 11.1 4.7 20.6 13.2 9.3 10.1 23.7 15.8 8.4 7.3 9.0 6.2 7.0 78.3 7.0 19.0 18.8 21.3 5.5 4.0 16.5 5.7 11.1 11.6 11.7 12.5 2.6 13.0 21.1 20.4 9.9 9.7 13.3 6.2 6.1 5.3 8.2 15.0 17.0 12.3 7.3 11.3 15.8 13.1 17.0 10.3 12.7 28.8 23.7 38.5 20.8 62.7 146.4 12.6 17.5 21.1 28.5 111.0 19.6 14.2 39.9 12.8 19.5 22.0 210.6 16.9 140.2 4.2 5.9 9.9 19.2 14.4 52.1 25.9 20.4 39.1 70.2 12.3 13.2 39.0 12.8 20.9 13.3 45.9 32.9 23.3 29.1 60.6 82.8 14.9 26.4 96.4 34.0 5.1 39.4 69.2 26.6 178.9 63.2 27.3 339.8 85.5 217.6 7.6 7.6 27.8 96.5 9.1 8.9 11.1 16.0 200.1 26.3 41.4 29.2 31.5 37.4 15.8 12.4 4.2 147.7 52.3 11.5 10.2 ATP11A "ATPIH, ATPIS, KIAA1021" ENSG00000068650 "ATPase phospholipid transporting 11A" P98196 13 112690329-112887168 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 218.0;Alveolar cells type 2: 215.0;Cone photoreceptor cells: 235.6;Glandular and luminal cells: 176.3;Oligodendrocytes: 138.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035583, HPA035584" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Vesicles "Golgi apparatus" "HPA035583: AB_10671106, HPA035584: AB_10672096" "unprognostic (1.67e-1)" "unprognostic (5.06e-3)" "unprognostic (1.58e-1)" "unprognostic (5.27e-2)" "unprognostic (6.58e-2)" "unprognostic (8.84e-2)" "unprognostic (5.87e-3)" "unprognostic (1.80e-2)" "unprognostic (6.97e-2)" "unprognostic (1.54e-3)" "unprognostic (3.93e-2)" "unprognostic (4.23e-1)" "prognostic favorable (7.44e-4)" "unprognostic (3.85e-2)" "unprognostic (3.69e-1)" "unprognostic (3.26e-2)" "unprognostic (7.40e-3)" 10.2 10.4 12.3 8.9 22.0 18.2 6.1 18.3 16.8 13.0 5.7 4.4 9.9 10.1 5.8 7.0 8.7 15.0 21.4 9.7 12.5 12.7 10.1 39.5 5.8 25.3 22.2 6.5 12.4 23.1 16.2 10.1 22.9 4.3 3.2 14.9 9.0 3.9 13.1 8.9 8.3 9.1 15.7 8.9 5.3 8.9 21.9 8.2 13.9 17.3 6.1 6.5 5.9 40.2 28.0 14.0 17.5 20.5 8.7 11.7 30.9 13.0 7.6 10.9 8.8 44.5 31.5 14.1 15.5 11.0 14.0 23.2 15.8 10.8 10.5 14.2 14.9 16.3 11.9 23.3 13.6 30.8 25.5 7.9 8.2 13.2 8.0 8.8 29.0 12.6 11.4 2.3 7.7 10.5 14.1 19.4 7.5 31.8 9.9 12.2 7.1 8.1 59.3 6.4 27.8 7.7 12.7 16.3 10.7 22.4 6.2 40.4 19.2 0.0 23.3 14.1 9.9 7.4 15.5 5.9 4.8 28.3 12.2 0.0 1.1 1.7 0.4 1.6 0.3 0.6 0.2 0.2 0.6 1.8 0.3 0.2 3.1 0.0 1.5 0.5 0.0 0.3 12.3 22.0 18.3 16.8 9.7 12.5 25.3 22.2 22.9 15.7 21.9 40.2 25.6 218.0 215.0 22.2 11.3 10.8 3.4 4.9 1.2 42.0 5.2 3.7 42.3 31.5 29.4 16.5 235.6 1.7 7.0 2.4 5.9 32.7 0.9 51.2 24.2 34.2 12.0 3.8 35.0 11.4 32.2 16.5 8.6 176.3 12.0 62.2 27.1 16.5 20.7 13.5 32.5 3.5 14.2 33.6 16.9 1.9 11.1 29.3 10.6 48.7 36.9 11.0 6.2 33.7 138.3 24.3 6.1 4.9 7.7 7.7 10.5 15.7 13.3 44.8 0.0 9.5 12.8 4.0 10.1 6.3 9.7 8.6 8.4 8.7 5.9 3.9 ATP6V0A1 "a1, ATP6N1, ATP6N1A, Stv1, Vph1, VPP1" ENSG00000033627 "ATPase H+ transporting V0 subunit a1" Q93050 17 42458844-42522582 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 130.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 294.0;Rod photoreceptor cells: 403.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022144 Enhanced Approved "Nuclear speckles,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "Nuclear speckles, Cytosol" "HPA022144: AB_1845189" "unprognostic (3.93e-2)" "unprognostic (2.02e-1)" "unprognostic (4.35e-2)" "unprognostic (2.22e-2)" "unprognostic (1.60e-2)" "unprognostic (8.69e-2)" "unprognostic (1.84e-2)" "unprognostic (8.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.85e-1)" "prognostic favorable (2.05e-4)" "unprognostic (3.25e-1)" "prognostic favorable (1.28e-4)" "unprognostic (3.07e-1)" "unprognostic (3.68e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (6.90e-4)" 17.7 28.2 30.6 18.0 35.2 21.5 16.3 16.8 42.7 13.4 0.0 22.1 34.6 20.9 19.6 17.4 17.1 22.7 18.9 43.6 44.1 37.4 21.0 24.1 13.1 25.6 26.2 20.0 17.4 86.0 39.0 21.2 34.6 17.4 20.5 130.7 13.5 18.6 59.3 28.1 24.3 21.5 12.1 21.8 16.3 18.7 30.9 15.2 30.3 25.3 14.9 11.9 12.8 27.2 18.4 37.0 22.1 40.1 36.5 31.7 12.9 12.7 23.3 26.4 34.2 23.9 39.9 3.4 22.6 26.2 36.2 38.7 34.5 21.5 30.4 28.3 36.2 29.2 27.3 19.0 22.7 12.8 50.9 23.5 30.3 42.4 18.0 32.6 18.9 13.2 108.0 111.3 39.7 15.8 5.1 11.3 14.3 23.9 0.4 0.2 23.0 51.2 30.2 14.4 60.9 32.0 19.7 17.7 37.1 28.8 43.0 19.0 11.4 22.3 0.9 33.0 15.3 45.0 66.1 6.8 29.7 0.2 26.5 21.6 14.5 11.2 1.0 4.4 1.6 4.7 0.7 0.2 12.2 7.3 1.2 0.9 18.7 0.1 3.3 6.2 3.7 6.6 30.6 35.2 16.8 42.7 43.6 44.1 25.6 26.2 34.6 12.1 30.9 27.2 20.0 19.2 48.0 47.0 23.0 19.8 56.7 15.7 32.5 164.8 15.7 16.5 21.1 28.6 18.3 14.7 294.0 34.3 16.7 46.2 11.7 16.3 4.0 32.8 27.4 22.2 84.9 45.8 125.0 18.5 15.7 31.0 23.4 74.0 24.1 74.5 16.4 37.8 53.8 95.9 112.3 27.3 12.2 37.8 29.2 3.9 17.4 42.8 40.9 38.4 17.7 59.3 3.1 61.3 80.5 24.2 37.6 23.7 13.8 32.7 56.9 32.5 11.4 403.4 6.6 39.4 32.3 38.8 18.2 21.7 20.2 99.9 6.9 35.0 24.5 14.9 ATP6V1B2 "ATP6B2, HO57, VATB, Vma2, VPP3" ENSG00000147416 "ATPase H+ transporting V1 subunit B2" P21281 8 20197381-20226819 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 256.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1130.7" "Group enriched" "Detected in all" 10 "dendritic cells: 336.8;granulocytes: 1130.7;monocytes: 682.0" "Cell line enhanced" "Detected in all" "SK-MEL-30: 317.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008147 Enhanced Supported Vesicles NA NA 310000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA008147: AB_1845195" "unprognostic (1.90e-1)" "unprognostic (7.24e-3)" "unprognostic (3.62e-2)" "unprognostic (2.57e-1)" "unprognostic (2.84e-2)" "unprognostic (5.59e-3)" "unprognostic (1.76e-2)" "unprognostic (3.78e-2)" "unprognostic (4.68e-2)" "unprognostic (4.23e-3)" "unprognostic (1.29e-2)" "unprognostic (1.34e-1)" "prognostic favorable (8.41e-4)" "unprognostic (2.41e-1)" "unprognostic (2.09e-2)" "unprognostic (2.47e-2)" "unprognostic (5.25e-2)" 46.4 76.4 112.6 71.9 111.2 45.7 35.3 72.8 126.0 30.1 72.5 38.0 43.9 29.4 31.0 51.3 32.8 39.0 38.2 124.0 135.5 145.8 49.2 72.7 54.1 103.4 120.0 27.5 34.5 71.4 74.5 50.5 138.2 28.1 43.0 205.7 40.4 27.0 66.7 62.5 57.8 40.1 74.8 66.1 32.8 67.8 100.3 50.2 33.4 64.7 48.9 44.5 36.1 99.5 44.2 71.5 87.4 29.2 117.7 72.3 79.1 96.6 61.5 121.5 125.2 81.7 25.4 77.7 38.4 93.1 123.7 36.8 70.1 64.6 129.0 32.9 47.2 54.2 29.9 63.6 137.6 39.0 108.0 65.0 57.9 76.0 69.3 134.1 77.2 101.2 82.0 72.8 132.5 25.0 114.6 46.2 65.6 64.6 31.5 46.6 113.4 40.8 112.9 68.2 68.0 97.9 46.9 62.7 317.9 72.4 81.6 70.7 82.8 61.1 46.3 101.9 78.5 29.4 42.7 90.9 84.6 91.6 158.4 183.7 682.0 485.9 52.9 618.6 57.7 50.2 54.1 56.8 336.8 44.5 54.4 53.7 1130.7 50.8 576.1 82.7 73.0 622.6 112.6 111.2 72.8 126.0 124.0 135.5 103.4 120.0 138.2 74.8 100.3 99.5 16.6 25.6 20.7 20.5 28.1 58.0 28.4 52.1 33.0 106.1 18.5 15.6 17.6 25.8 28.8 29.5 102.2 109.2 38.9 23.3 80.3 43.2 40.8 20.2 13.6 24.1 74.4 35.8 64.3 38.5 56.4 38.8 25.0 35.9 22.2 22.3 25.7 34.7 178.5 190.1 68.0 21.4 36.7 185.2 178.7 24.4 19.6 167.6 104.9 30.0 169.1 51.5 20.6 27.6 29.0 45.2 19.7 28.2 20.7 17.4 75.0 256.7 18.0 137.8 13.1 29.3 34.2 121.6 55.3 43.3 71.6 124.6 27.1 23.1 24.7 20.1 ATP8A1 ATPIA ENSG00000124406 "ATPase phospholipid transporting 8A1" Q9Y2Q0 4 42408373-42657105 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.5" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1218.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.5" "Region enhanced" "Detected in all" "white matter: 84.5" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 27.5;Daudi: 46.3;HEL: 16.4;REH: 16.1;SH-SY5Y: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052935 Enhanced Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA052935: AB_2681992" "unprognostic (8.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (6.59e-2)" "unprognostic (6.82e-3)" "unprognostic (7.69e-2)" "unprognostic (2.02e-3)" "unprognostic (3.99e-1)" "unprognostic (2.99e-3)" "unprognostic (4.39e-2)" "unprognostic (9.71e-2)" "prognostic favorable (5.54e-10)" "unprognostic (2.43e-1)" "unprognostic (3.25e-1)" "unprognostic (8.21e-2)" "unprognostic (2.25e-1)" 2.8 8.9 5.8 9.5 26.7 23.4 3.7 3.6 18.3 2.1 0.0 12.8 4.2 2.4 12.2 2.2 2.4 2.5 8.4 14.5 11.7 3.8 1.7 11.8 15.0 9.5 4.4 16.2 7.0 36.0 2.2 2.4 9.5 8.3 11.7 19.4 4.4 5.3 10.0 1.7 8.9 2.8 18.1 9.0 12.5 2.1 9.5 9.9 39.7 15.6 11.8 2.5 1.5 84.5 0.0 0.1 0.4 27.5 0.1 0.1 0.1 0.1 0.0 0.0 0.0 3.0 0.4 46.3 12.6 0.2 0.0 2.4 6.5 0.1 0.0 7.4 4.5 16.4 1.6 0.7 0.1 4.0 0.3 0.4 0.0 0.0 0.0 0.6 0.2 10.3 0.0 5.1 0.0 2.0 6.0 1.4 2.0 1.9 0.6 16.1 0.0 5.3 9.5 0.6 4.9 14.8 0.3 9.4 0.0 1.1 3.1 0.0 0.4 0.0 2.0 0.5 0.0 1.7 0.0 9.4 0.7 5.6 0.2 0.0 0.6 0.6 3.7 0.2 1.9 1.5 1.1 4.1 0.6 2.5 1.7 4.4 0.5 2.2 2.5 2.4 1.0 0.6 5.8 26.7 3.6 18.3 14.5 11.7 9.5 4.4 9.5 18.1 9.5 84.5 26.1 28.9 80.1 136.1 23.3 1.5 1.8 0.6 2.2 19.7 4.0 1.5 14.4 0.0 5.3 5.5 81.3 0.0 52.9 48.4 3.9 0.2 4.6 1.3 1.3 13.6 84.6 13.9 295.9 2.5 0.1 4.8 19.9 4.2 8.2 26.5 16.8 1.1 1.6 62.2 255.9 28.6 0.0 8.8 4.6 2.9 3.4 8.9 3.6 31.9 5.1 2.2 33.0 144.8 1218.1 0.6 10.2 1.9 37.6 9.6 45.6 2.0 0.3 38.1 0.0 6.3 2.7 1.5 3.6 5.0 1.4 0.0 51.6 8.6 25.0 3.0 AXIN1 PPP1R49 ENSG00000103126 "Axin 1" O15169 16 287440-352723 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012987 Approved Supported Nucleoli,Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoli, Vesicles" "CAB012987: AB_2533178" "unprognostic (3.81e-2)" "unprognostic (1.56e-1)" "unprognostic (1.90e-1)" "unprognostic (7.64e-2)" "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (3.38e-5)" "unprognostic (1.23e-1)" "unprognostic (3.58e-1)" "unprognostic (1.56e-1)" "unprognostic (4.58e-2)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" "unprognostic (4.41e-2)" "unprognostic (1.94e-1)" "unprognostic (1.23e-2)" "unprognostic (1.03e-1)" 11.9 9.3 10.5 9.2 10.8 23.0 11.5 14.8 12.5 12.9 9.1 17.1 12.3 13.2 3.1 16.3 11.8 6.2 11.6 10.0 9.2 11.6 11.2 13.7 10.5 10.2 10.2 13.8 13.0 7.2 12.6 5.8 9.8 12.9 6.9 2.6 11.5 6.0 21.1 20.1 15.0 5.4 9.2 15.0 12.9 11.8 10.1 12.5 11.9 7.0 6.6 14.5 13.1 11.9 18.1 25.6 13.4 23.7 9.8 9.0 28.0 11.9 10.8 16.1 13.8 37.9 20.4 27.7 18.0 12.3 19.4 25.4 21.1 18.5 7.2 27.5 34.6 18.0 21.9 27.6 16.6 20.9 19.3 9.0 31.7 16.6 20.3 14.1 10.7 19.8 45.6 14.8 7.4 48.1 22.7 14.5 30.6 21.6 15.4 42.4 12.2 38.8 12.2 10.5 30.4 18.6 22.6 24.9 38.3 10.0 16.5 26.1 12.4 15.9 17.0 18.5 17.5 17.3 18.1 34.2 7.5 13.7 15.9 1.2 0.9 5.0 8.3 0.8 7.6 1.5 2.4 5.8 0.7 1.2 2.4 3.4 2.7 3.5 0.6 1.2 2.6 2.3 10.5 10.8 14.8 12.5 10.0 9.2 10.2 10.2 9.8 9.2 10.1 11.9 7.9 3.2 8.6 4.9 5.7 18.4 7.6 8.5 5.7 4.3 11.2 9.5 4.9 5.7 7.2 3.7 0.0 3.5 30.1 27.4 0.0 7.2 1.4 10.2 7.0 6.3 10.8 8.6 18.5 6.9 27.5 6.7 15.3 14.4 10.8 10.5 5.7 5.1 7.5 5.0 12.7 15.1 6.1 6.2 9.0 2.1 5.3 6.7 10.6 1.0 5.7 4.5 28.8 8.5 8.9 11.0 12.2 4.9 7.0 13.4 11.1 2.4 7.7 5.7 13.1 8.7 7.6 5.5 8.8 7.2 15.2 3.7 12.4 5.0 15.7 10.5 B4GALNT3 "B4GalNac-T3, FLJ16224, FLJ40362" ENSG00000139044 "Beta-1,4-N-acetyl-galactosaminyltransferase 3" Q6L9W6 12 459939-563509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 61.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 81.1;Gastric mucus-secreting cells: 128.0;Glandular and luminal cells: 47.4;Late spermatids: 89.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 33.5;HDLM-2: 13.2;HEK 293: 12.5;NTERA-2: 14.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA011404 Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" Vesicles "HPA011404: AB_1845242" "unprognostic (2.38e-2)" "unprognostic (9.59e-3)" "unprognostic (1.38e-1)" "prognostic favorable (1.69e-10)" "unprognostic (4.22e-2)" "unprognostic (4.63e-2)" "unprognostic (1.46e-2)" "unprognostic (9.53e-3)" "unprognostic (3.29e-1)" "unprognostic (1.61e-1)" "unprognostic (1.23e-1)" "unprognostic (1.02e-1)" "unprognostic (5.46e-2)" "unprognostic (9.99e-3)" "unprognostic (2.82e-1)" "unprognostic (2.48e-2)" "unprognostic (2.98e-1)" 0.2 7.0 0.5 3.2 0.7 2.1 1.3 0.0 1.0 7.4 1.0 18.4 1.0 6.2 2.7 7.5 3.7 2.2 23.9 0.5 0.0 4.6 0.1 5.2 0.1 0.0 0.0 0.4 2.6 16.9 9.3 0.1 0.0 2.0 12.5 0.1 4.8 0.7 1.5 14.8 2.0 2.2 0.0 0.3 61.0 8.0 0.0 2.3 2.3 0.1 0.7 1.4 5.6 0.7 0.0 0.0 0.3 1.2 0.0 0.0 33.5 0.0 0.0 0.0 0.0 8.0 6.6 0.0 0.9 0.0 0.7 3.6 8.0 1.1 0.1 13.2 12.5 0.0 0.0 1.8 0.0 0.1 5.3 0.0 5.3 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.4 0.0 0.1 14.8 10.5 0.6 0.5 5.0 0.0 7.1 6.8 3.8 2.7 0.8 0.3 1.0 4.9 0.8 2.9 0.0 0.0 2.7 0.2 0.9 0.0 0.0 0.0 0.0 9.2 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 7.0 1.3 0.3 7.5 6.0 3.4 0.0 0.6 2.9 0.6 15.1 1.5 6.2 9.2 0.0 0.0 0.6 81.1 0.0 12.0 26.3 20.4 4.8 0.6 10.3 0.0 32.6 4.8 0.1 1.6 128.0 47.4 0.0 0.1 0.0 0.1 0.7 0.0 5.2 18.6 2.0 0.0 1.1 89.2 0.0 0.5 0.0 2.8 0.6 0.0 0.0 1.0 3.6 16.6 33.4 0.0 0.2 12.7 1.9 0.2 9.1 0.2 0.0 0.2 0.8 2.8 1.3 0.9 17.3 0.0 1.5 1.9 26.1 14.4 BIRC6 BRUCE ENSG00000115760 "Baculoviral IAP repeat containing 6" Q9NR09 2 32357028-32618899 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 272.0;Inhibitory neurons: 291.3;Oligodendrocytes: 361.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 9.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074409, HPA074738" Approved Supported "Golgi apparatus,Vesicles,Mitotic spindle" Yes No "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Golgi apparatus, Vesicles" "Mitotic spindle" "HPA074409: , HPA074738: AB_2686710" "unprognostic (3.38e-2)" "unprognostic (8.13e-3)" "unprognostic (8.88e-2)" "unprognostic (7.06e-3)" "unprognostic (6.69e-3)" "unprognostic (9.01e-2)" "unprognostic (4.51e-2)" "unprognostic (2.07e-1)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (4.49e-2)" "unprognostic (4.00e-2)" "unprognostic (2.07e-2)" "unprognostic (1.30e-1)" "unprognostic (4.61e-1)" "unprognostic (7.32e-2)" "unprognostic (3.37e-1)" 4.6 4.7 3.1 6.7 9.7 11.3 8.9 13.9 5.7 7.7 6.3 7.6 5.0 6.8 5.2 5.3 6.2 5.8 4.9 4.6 3.7 7.6 8.9 5.4 9.6 6.4 5.5 12.0 14.7 10.9 2.9 6.9 7.3 6.2 7.5 15.5 5.5 5.9 6.1 6.7 5.4 6.1 4.4 8.5 7.1 6.8 5.6 14.7 11.4 8.8 9.7 7.2 3.1 16.3 21.7 17.8 16.1 7.9 14.9 19.1 11.3 10.8 14.1 11.0 11.3 14.2 5.7 23.6 7.3 19.7 13.2 10.1 22.9 15.1 13.9 18.8 10.5 31.2 11.3 10.7 7.9 32.4 11.9 12.4 6.9 18.0 16.2 10.1 17.7 5.4 25.6 10.0 11.9 9.3 15.5 7.5 11.7 9.2 10.5 14.6 26.6 8.2 9.2 23.4 11.7 18.4 18.6 10.8 8.2 12.5 6.4 11.5 28.7 13.0 13.3 9.1 15.3 13.9 20.0 30.6 10.1 15.1 8.7 9.7 0.9 0.6 1.3 0.7 1.8 0.8 1.0 1.2 0.7 1.8 1.1 1.4 1.5 1.6 1.5 1.6 1.0 0.5 3.1 9.7 13.9 5.7 4.6 3.7 6.4 5.5 7.3 4.4 5.6 16.3 53.9 32.1 30.5 239.3 74.8 46.0 28.6 34.7 41.5 60.8 40.0 23.4 45.8 38.6 42.7 36.8 191.8 35.0 93.4 70.1 1.9 26.9 45.9 39.3 58.0 49.8 32.5 34.3 272.0 31.2 22.0 39.7 68.3 63.1 29.9 52.1 45.7 47.5 29.8 69.0 291.3 43.3 26.4 54.7 60.0 17.6 45.4 59.1 23.2 202.4 67.2 34.9 64.9 231.8 361.3 34.3 30.3 59.0 70.9 46.4 48.5 22.6 30.6 88.2 39.5 56.0 49.1 53.7 46.2 49.7 54.8 38.0 72.4 52.8 45.3 44.0 BLOC1S5 "dJ303A1.3, MU, MUTED" ENSG00000188428 "Biogenesis of lysosomal organelles complex 1 subunit 5" Q8TDH9 6 8013567-8064396 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 41.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025613, HPA077525" Uncertain Supported Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "CAB025613: , HPA077525: AB_2686843" "unprognostic (1.54e-1)" "unprognostic (8.21e-2)" "unprognostic (1.26e-2)" "unprognostic (1.24e-2)" "unprognostic (1.92e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (8.12e-4)" "unprognostic (4.24e-2)" "unprognostic (1.20e-2)" "unprognostic (1.47e-2)" "unprognostic (2.87e-2)" "unprognostic (1.00e-1)" "unprognostic (1.62e-3)" "unprognostic (1.83e-1)" "unprognostic (1.13e-1)" "unprognostic (6.16e-2)" "unprognostic (7.60e-3)" 6.8 7.0 3.6 6.3 4.2 3.9 10.5 3.9 4.7 8.1 3.0 6.4 4.2 7.0 6.9 6.6 6.4 6.1 6.0 3.3 4.7 15.7 11.4 5.9 9.9 4.4 4.2 9.9 4.7 9.6 3.1 6.8 4.5 6.5 5.8 5.2 4.7 9.2 6.5 6.4 5.0 6.6 4.0 7.4 6.0 3.7 3.9 15.6 10.1 8.6 10.6 6.2 5.3 4.6 6.1 7.0 14.7 18.9 15.7 18.8 9.6 6.7 9.4 9.5 9.4 13.6 5.8 21.8 43.9 8.6 10.8 5.4 10.8 5.4 13.6 20.6 11.5 13.1 4.8 25.8 13.4 23.2 14.8 8.4 13.4 9.6 14.4 14.5 17.3 17.3 27.7 3.9 13.6 6.7 26.6 15.1 7.9 14.3 9.4 21.5 17.0 33.8 17.6 5.4 13.5 7.2 6.8 10.3 21.3 26.4 12.9 11.8 7.2 15.1 10.7 8.9 5.9 16.5 37.3 19.7 6.2 17.9 15.9 16.2 9.4 18.3 11.8 12.3 15.7 18.9 15.3 15.2 16.6 17.7 15.2 15.9 2.3 19.6 6.7 7.2 15.2 11.8 3.6 4.2 3.9 4.7 3.3 4.7 4.4 4.2 4.5 4.0 3.9 4.6 18.1 12.8 6.9 0.0 14.6 6.0 8.3 6.8 8.6 7.0 7.1 9.9 7.3 0.0 7.9 25.8 2.1 12.5 15.6 5.9 35.2 9.9 7.5 11.5 12.4 10.7 1.8 7.2 0.0 8.7 9.2 10.6 7.7 19.5 16.5 14.5 0.0 0.0 7.8 6.7 0.0 6.9 2.0 0.0 6.1 7.8 9.6 11.0 3.6 0.0 10.7 13.2 12.3 0.0 0.0 10.1 3.9 12.4 7.3 8.4 6.7 41.8 7.7 8.4 0.0 12.4 9.3 5.8 14.4 8.9 7.5 8.2 12.7 22.5 6.6 7.5 BORCS5 "LOH12CR1, LOH1CR12" ENSG00000165714 "BLOC-1 related complex subunit 5" Q969J3 12 12357078-12471233 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 42.6;T-cells: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039509, HPA043627" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "HPA039509: AB_2676550, HPA043627: AB_2678588" "unprognostic (1.82e-1)" "unprognostic (2.87e-1)" "unprognostic (2.81e-1)" "unprognostic (2.41e-1)" "unprognostic (8.00e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (6.78e-2)" "unprognostic (6.16e-2)" "unprognostic (2.79e-2)" "unprognostic (6.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-3)" "unprognostic (1.50e-2)" "unprognostic (2.14e-1)" "unprognostic (1.72e-1)" "unprognostic (9.51e-2)" 6.3 8.1 5.1 2.5 7.1 6.2 6.1 5.2 6.4 6.6 2.3 5.8 1.7 5.8 5.8 8.0 5.7 2.4 7.1 4.1 5.8 5.9 8.5 6.5 2.9 5.6 5.4 4.9 7.2 3.8 7.1 2.7 6.2 5.9 2.2 2.8 5.4 1.9 8.4 8.7 4.7 3.0 4.7 6.2 5.9 9.1 5.4 3.1 4.6 3.3 3.9 5.6 6.8 8.2 3.9 4.1 2.9 3.0 6.4 8.7 3.3 3.4 3.9 4.1 5.1 10.0 3.9 4.9 2.0 5.5 2.9 2.7 5.0 4.9 4.4 14.0 4.5 2.7 3.9 5.7 6.1 2.9 3.8 4.9 3.5 5.6 6.5 6.5 4.9 6.1 3.8 6.6 5.4 8.4 4.2 3.0 9.0 4.1 2.6 3.4 4.1 5.3 5.1 2.6 3.6 4.1 3.3 3.0 7.5 9.6 2.3 3.1 4.1 2.7 6.1 3.5 3.1 3.4 3.2 11.1 5.8 4.4 4.6 2.8 6.1 9.5 10.1 10.3 11.9 7.7 11.5 11.2 7.3 5.9 7.6 7.7 6.7 12.4 6.7 5.1 14.2 7.0 5.1 7.1 5.2 6.4 4.1 5.8 5.6 5.4 6.2 4.7 5.4 8.2 11.1 9.6 2.3 0.0 37.9 0.0 11.9 0.0 10.8 16.9 10.5 8.4 0.0 10.0 2.5 7.3 12.5 9.2 42.6 2.2 9.8 9.5 5.6 8.8 9.0 6.7 4.9 5.9 0.0 12.4 11.7 8.3 19.9 8.9 2.5 7.4 6.1 5.1 14.5 13.5 0.0 3.8 0.0 11.0 0.0 3.9 5.3 26.3 0.0 0.0 19.0 12.5 14.4 0.0 0.0 9.5 3.5 7.2 33.0 9.1 10.3 14.1 2.9 16.6 26.3 8.3 8.1 23.4 8.6 14.6 0.0 14.5 39.5 7.5 4.6 8.3 BST2 "CD317, tetherin" ENSG00000130303 "Bone marrow stromal cell antigen 2" Q10589 19 17402939-17405630 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Antiviral defense, B-cell activation, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 694.2" "Cell type enhanced" "Detected in many" "Adipocytes: 1193.2;Hepatic stellate cells: 455.8;Theca cells: 490.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 615.0;Karpas-707: 603.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA017060, HPA073472" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 260000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles" "HPA017060: AB_1845467, HPA073472: " "prognostic favorable (6.69e-4)" "unprognostic (1.75e-1)" "unprognostic (8.42e-3)" "unprognostic (8.93e-3)" "unprognostic (4.87e-2)" "unprognostic (2.25e-1)" "unprognostic (2.26e-1)" "unprognostic (1.07e-1)" "unprognostic (3.25e-1)" "unprognostic (6.46e-2)" "unprognostic (6.56e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.56e-9)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (1.08e-1)" "unprognostic (2.46e-2)" 226.0 509.8 86.7 95.6 87.6 103.7 152.9 84.0 125.7 93.4 81.7 94.1 47.4 58.7 59.5 40.3 248.0 109.4 111.2 85.1 84.5 160.1 227.8 141.4 128.0 101.5 85.9 694.2 26.3 13.8 56.8 203.0 88.4 88.6 33.3 2.0 77.7 105.2 46.1 24.8 109.1 76.0 97.0 238.5 84.1 35.4 91.1 123.5 54.0 50.8 65.8 82.9 88.6 90.8 327.0 0.5 0.9 145.6 0.0 1.0 49.6 1.3 24.9 459.5 615.0 150.5 286.1 252.2 338.2 197.6 14.6 1.3 212.9 23.9 14.3 279.1 1.8 3.6 525.7 149.8 256.7 120.1 304.7 1.3 0.0 153.0 0.1 4.4 119.0 6.0 146.3 603.4 0.0 89.5 57.7 208.6 158.0 0.1 407.9 105.5 0.8 530.7 110.1 1.5 0.6 1.4 325.5 12.3 410.5 12.3 243.1 166.3 1.5 1.9 11.4 0.5 3.3 308.3 439.3 168.0 1.3 470.8 2.2 229.7 345.3 125.3 171.4 385.5 163.0 115.2 143.2 160.0 283.8 146.5 114.8 132.6 113.3 353.2 359.3 421.7 143.3 367.9 86.7 87.6 84.0 125.7 85.1 84.5 101.5 85.9 88.4 97.0 91.1 90.8 1193.2 57.7 13.6 4.9 90.7 33.1 19.6 255.7 48.9 0.2 86.2 168.5 7.0 50.1 68.5 49.7 0.0 7.8 184.2 1.5 37.2 18.7 10.7 27.8 11.2 420.2 1.2 74.0 0.0 1.2 61.5 152.4 14.8 50.1 227.8 260.9 455.8 211.1 388.9 0.0 0.0 2.8 28.5 189.4 187.6 12.0 346.7 220.4 74.7 32.8 214.5 1.3 211.2 0.5 0.3 3.3 4.8 419.4 192.8 10.3 3.7 1.3 27.4 2.1 164.3 30.7 146.3 1.3 1.2 15.5 26.1 13.1 135.8 490.6 5.0 28.6 BTBD3 "dJ742J24.1, KIAA0952" ENSG00000132640 "BTB domain containing 3" Q9Y2F9 20 11890723-11926609 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.9" "Cell type enhanced" "Detected in all" "Endometrial stromal cells: 223.0;Oligodendrocytes: 254.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 241.1;HeLa: 186.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041424, HPA042048" Uncertain Supported Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA041424: AB_10794667, HPA042048: AB_10796469" "unprognostic (3.93e-2)" "unprognostic (2.25e-1)" "unprognostic (1.32e-1)" "unprognostic (3.56e-3)" "unprognostic (4.24e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (2.51e-5)" "prognostic unfavorable (6.94e-4)" "unprognostic (4.87e-2)" "unprognostic (2.95e-1)" "unprognostic (1.07e-2)" "unprognostic (7.05e-2)" "unprognostic (6.66e-2)" "unprognostic (7.68e-3)" "unprognostic (1.67e-1)" "unprognostic (6.29e-2)" "unprognostic (1.37e-2)" 11.2 22.1 20.6 7.1 34.2 12.2 12.7 66.2 80.9 16.9 12.3 21.4 10.7 18.7 7.9 9.9 15.4 13.4 13.9 79.6 30.9 11.6 7.7 12.2 4.1 30.5 24.7 11.5 13.7 11.2 8.9 42.0 23.1 15.1 17.5 42.5 13.9 10.6 15.9 20.7 10.9 16.5 24.2 7.8 27.3 14.7 23.7 10.8 11.5 13.2 3.1 18.4 10.1 64.7 7.0 19.5 52.1 241.1 10.6 11.3 14.0 21.9 14.0 24.3 15.5 11.2 10.7 2.0 18.1 31.7 9.6 18.1 27.2 15.4 39.1 0.1 24.1 7.1 186.9 23.9 11.1 11.6 4.2 20.2 18.8 21.8 17.5 13.4 13.8 12.0 12.7 18.8 24.3 5.1 14.0 10.7 25.0 29.0 5.5 18.4 10.4 7.0 22.2 34.0 22.7 40.0 60.8 24.6 53.3 27.9 14.4 11.5 10.7 13.2 33.6 12.4 24.6 6.9 9.9 0.3 8.6 3.2 87.6 0.0 1.2 0.1 0.0 1.7 0.0 0.0 0.0 0.0 1.4 0.1 0.3 0.0 0.3 0.7 3.5 1.0 0.0 0.6 20.6 34.2 66.2 80.9 79.6 30.9 30.5 24.7 23.1 24.2 23.7 64.7 17.4 16.0 8.4 24.5 2.8 16.6 10.8 8.0 18.8 15.3 15.2 11.9 16.5 10.0 8.3 5.5 79.2 23.3 1.0 41.0 3.9 9.8 8.3 51.3 223.0 25.0 20.9 4.6 46.9 8.3 4.0 15.6 28.5 55.8 2.5 9.4 33.5 8.5 8.5 65.6 38.0 9.4 10.2 4.8 13.4 13.6 16.4 6.5 14.2 39.4 3.2 17.7 1.0 61.9 254.9 9.7 25.9 8.6 2.7 13.2 11.4 6.6 24.1 56.9 6.6 19.9 18.6 10.0 16.1 11.7 17.2 21.8 1.8 42.0 13.3 11.3 C11orf91 ENSG00000205177 "Chromosome 11 open reading frame 91" Q3C1V1 11 33698261-33700801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.5" "Cell type enhanced" "Detected in some" "Early spermatids: 16.6;Late spermatids: 4.0;Sertoli cells: 6.6;Spermatocytes: 12.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 16.2;hTERT-HME1: 10.0;HUVEC TERT2: 8.2;TIME: 12.6;U-2197: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047064, HPA050487" Uncertain Supported Vesicles NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA047064: AB_2679920, HPA050487: AB_2681142" "unprognostic (9.22e-3)" "unprognostic (1.51e-2)" "unprognostic (1.76e-1)" "unprognostic (6.60e-2)" "unprognostic (1.62e-2)" "unprognostic (3.63e-2)" "unprognostic (2.31e-1)" "unprognostic (5.68e-3)" "unprognostic (7.41e-2)" "unprognostic (2.97e-2)" "unprognostic (1.99e-2)" "unprognostic (3.01e-1)" "unprognostic (8.33e-2)" "unprognostic (4.06e-2)" "unprognostic (3.95e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" 4.8 0.2 0.3 0.6 0.3 1.0 1.5 1.2 2.0 0.1 0.0 0.4 0.0 0.2 0.1 2.9 0.3 4.7 0.8 0.2 0.5 1.4 0.2 1.1 0.2 0.3 0.5 0.2 1.5 0.0 0.1 0.5 0.6 0.2 0.0 0.2 0.5 0.2 0.5 1.0 0.3 0.8 0.4 0.0 2.1 9.5 0.3 0.2 0.4 0.0 0.4 1.4 0.3 0.6 0.2 0.0 0.2 1.5 0.0 0.0 0.0 1.8 0.0 0.9 0.4 0.3 0.6 0.0 0.1 1.9 0.2 0.7 0.5 16.2 1.3 0.5 0.0 0.0 4.0 0.9 0.3 0.0 0.0 0.0 0.1 1.2 10.0 0.5 8.2 0.2 0.0 2.5 3.9 0.0 0.0 0.3 0.0 0.1 5.0 0.0 0.0 0.0 1.1 2.1 0.0 0.3 0.0 1.6 0.1 0.5 0.0 0.0 12.6 1.2 0.3 10.3 0.3 0.7 0.6 0.0 2.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.2 2.0 0.2 0.5 0.3 0.5 0.6 0.4 0.3 0.6 1.2 0.0 0.0 0.3 0.0 0.0 2.2 0.0 0.0 0.0 0.4 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 16.6 0.4 0.2 0.6 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.3 0.1 0.0 6.6 0.1 0.3 12.3 0.4 0.3 0.0 0.1 0.0 0.0 0.0 1.5 C5AR1 "C5A, C5AR, C5R1, CD88" ENSG00000197405 "Complement C5a receptor 1" P21730 19 47290023-47322066 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 125.5;lymphoid tissue: 84.8" "Group enriched" "Detected in many" 4 "Hofbauer cells: 130.9;Kupffer cells: 228.3;Langerhans cells: 122.4;Macrophages: 446.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 394.0" "Group enriched" "Detected in many" 42 "granulocytes: 394.0;monocytes: 115.9" "Cell line enhanced" "Detected in some" "A549: 3.9;CAPAN-2: 4.1;HMC-1: 4.7;U-87 MG: 6.2;U-937: 6.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB002720, HPA014520, HPA048012" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" Vesicles "CAB002720: , HPA014520: AB_1846337, HPA048012: " "unprognostic (5.95e-2)" "prognostic favorable (4.71e-4)" "unprognostic (1.70e-2)" "unprognostic (1.25e-1)" "unprognostic (4.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-2)" "unprognostic (4.41e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (9.55e-4)" "unprognostic (2.02e-1)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.96e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.82e-2)" "unprognostic (6.54e-2)" 72.7 18.2 3.3 84.8 3.1 125.5 8.5 2.4 9.0 11.8 21.6 9.8 2.5 7.5 1.4 8.3 23.9 38.8 11.7 3.9 8.2 9.7 18.0 43.1 11.5 8.9 6.9 5.0 8.9 4.8 51.8 31.8 8.4 5.3 4.2 4.4 5.1 2.5 1.9 2.3 5.8 28.1 5.7 38.2 7.2 2.6 10.5 7.1 3.6 5.8 4.3 37.1 4.6 11.6 1.0 3.9 0.1 0.1 0.7 0.2 0.6 0.7 0.5 0.2 0.1 0.2 4.1 0.3 0.7 0.9 0.4 1.4 0.2 0.5 0.2 0.7 0.5 0.1 3.8 0.6 0.4 1.5 4.7 0.3 2.2 0.4 0.3 0.6 0.0 0.2 0.2 1.7 0.1 1.1 0.2 2.5 1.2 0.2 0.3 0.2 0.1 0.3 1.3 0.9 0.0 0.0 0.3 0.3 0.6 0.5 0.2 2.2 0.0 0.1 2.1 0.3 0.1 0.2 0.3 0.3 6.2 6.5 0.2 41.6 53.8 38.8 0.4 80.4 0.3 0.4 0.3 0.2 6.1 0.6 0.3 0.3 394.0 0.5 115.9 1.1 0.3 19.3 3.3 3.1 2.4 9.0 3.9 8.2 8.9 6.9 8.4 5.7 10.5 11.6 4.4 3.2 20.8 0.0 5.1 5.1 1.0 3.4 2.8 1.0 2.1 4.4 2.9 1.5 15.3 1.8 2.1 0.8 1.5 1.6 3.9 0.0 1.3 17.3 1.8 6.3 0.0 0.4 1.5 0.0 1.5 5.3 1.1 4.6 25.2 0.1 2.9 8.3 130.9 0.0 0.6 0.8 4.1 228.3 122.4 1.3 0.6 446.7 5.4 5.6 56.3 0.2 0.0 1.0 0.3 0.1 0.1 0.0 4.9 0.5 0.7 1.3 40.7 4.3 13.1 4.1 2.8 0.5 0.9 1.4 3.0 1.5 3.3 0.0 1.3 0.5 C9orf72 "DENND9, DENNL72, MGC23980" ENSG00000147894 "C9orf72-SMCR8 complex subunit" Q96LT7 9 27535640-27573866 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Guanine-nucleotide releasing factor" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 127.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 24.3;classical monocyte: 32.0;intermediate monocyte: 44.7;myeloid DC: 25.2;neutrophil: 34.3;non-classical monocyte: 36.9" "Group enriched" "Detected in all" 8 "dendritic cells: 25.2;granulocytes: 34.3;monocytes: 44.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023873 Uncertain Supported "Vesicles,Midbody ring,Cytosol" "Intracellular and membrane" Yes NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" "Vesicles, Cytosol" "Midbody ring" "HPA023873: AB_1845834" "unprognostic (1.78e-2)" "unprognostic (5.01e-2)" "unprognostic (7.63e-2)" "unprognostic (9.78e-3)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (1.99e-3)" "unprognostic (2.45e-1)" "unprognostic (2.05e-2)" "unprognostic (2.16e-2)" "unprognostic (9.81e-2)" "unprognostic (1.44e-2)" "unprognostic (9.29e-2)" "unprognostic (1.10e-1)" "unprognostic (2.89e-2)" "unprognostic (9.13e-2)" 11.7 12.1 9.5 16.6 9.5 25.3 9.4 21.0 12.5 9.8 12.4 8.8 6.8 12.0 11.3 7.6 16.0 10.2 9.3 9.7 13.5 7.0 16.0 17.7 9.2 14.6 11.9 24.2 9.6 6.9 16.2 12.1 12.5 14.2 7.8 31.3 6.7 5.8 14.9 8.8 8.3 8.6 12.4 16.8 7.8 17.6 11.3 11.1 13.1 9.9 8.8 9.2 8.5 14.5 4.4 3.7 28.7 4.4 5.7 7.0 4.4 5.9 4.9 3.5 1.8 0.4 1.4 10.2 3.7 5.3 7.5 3.1 9.4 7.2 2.5 19.8 3.6 4.9 11.0 3.0 8.9 3.4 5.2 7.3 8.6 0.8 16.1 3.5 7.6 11.1 9.8 18.6 4.3 0.8 6.6 5.0 14.2 6.8 16.0 2.4 9.5 5.1 2.8 3.3 9.9 24.4 4.0 4.4 3.7 10.9 3.7 2.9 6.6 0.0 14.5 8.6 4.0 4.8 15.8 6.8 11.4 11.0 3.8 24.3 32.0 2.4 1.9 44.7 3.3 3.4 2.7 2.5 25.2 2.5 4.6 2.9 34.3 4.3 36.9 3.9 4.0 10.0 9.5 9.5 21.0 12.5 9.7 13.5 14.6 11.9 12.5 12.4 11.3 14.5 15.4 16.0 14.7 19.2 43.2 35.9 50.7 15.0 26.2 22.1 7.2 6.6 15.6 4.3 15.2 7.3 20.9 21.2 11.7 5.0 1.9 8.4 2.6 94.4 11.8 15.0 11.4 3.0 53.0 9.3 7.3 18.7 16.8 57.6 16.5 18.4 8.2 9.3 25.8 11.8 58.9 12.5 10.2 71.9 127.8 4.2 6.2 94.8 19.6 42.2 58.2 45.2 3.1 30.2 60.9 8.6 11.1 3.8 10.7 30.0 4.1 5.4 80.7 27.5 0.0 17.5 20.6 29.2 20.9 15.2 29.1 34.6 18.2 7.9 5.1 37.6 CADPS2 CAPS2 ENSG00000081803 "Calcium dependent secretion activator 2" Q86UW7 7 122318411-122886759 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 96.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 682.7;Microglial cells: 180.8;Oligodendrocyte precursor cells: 111.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 96.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 43.5;Karpas-707: 56.3;OE19: 63.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 159.9" HPA056398 Approved Nucleoplasm,Vesicles NA NA "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "HPA056398: AB_2683117" "unprognostic (1.93e-1)" "unprognostic (5.05e-2)" "unprognostic (1.91e-1)" "unprognostic (3.67e-3)" "unprognostic (8.69e-3)" "unprognostic (9.13e-2)" "unprognostic (1.19e-1)" "unprognostic (1.33e-1)" "unprognostic (4.07e-1)" "unprognostic (4.33e-2)" "unprognostic (3.93e-2)" "unprognostic (1.30e-1)" "prognostic favorable (1.01e-7)" "unprognostic (9.93e-2)" "unprognostic (1.37e-1)" "unprognostic (2.71e-2)" "unprognostic (3.45e-2)" 10.3 21.1 9.2 4.5 16.3 0.1 18.3 96.2 30.9 29.8 5.8 10.7 12.6 35.0 30.3 4.5 11.0 15.6 10.2 14.2 14.4 38.3 13.2 18.0 3.5 4.9 40.1 9.9 26.0 12.0 13.8 6.0 7.9 19.4 10.7 7.2 48.3 18.5 2.4 4.0 10.0 21.7 6.2 6.7 20.0 4.0 17.4 4.9 18.3 7.8 3.8 9.3 8.5 18.7 0.0 0.1 3.4 0.0 5.1 5.2 0.3 0.5 13.5 2.9 13.4 0.1 12.6 0.0 0.0 6.4 0.4 0.1 0.4 1.9 1.3 0.0 11.1 4.4 0.1 25.1 16.9 0.0 0.2 5.5 2.4 2.3 1.7 11.8 43.5 0.0 0.0 56.3 0.2 30.9 0.0 0.1 12.6 63.6 21.4 0.0 0.0 23.2 0.6 14.3 20.5 0.0 0.6 24.4 1.2 3.2 9.5 0.1 12.5 4.7 3.1 0.1 8.9 16.8 0.7 0.0 18.1 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 16.3 96.2 30.9 14.2 14.4 4.9 40.1 7.9 6.2 17.4 18.7 29.3 9.6 43.9 85.2 3.1 2.2 7.9 7.3 10.2 0.6 36.7 22.4 12.9 11.5 14.4 40.5 0.0 0.4 0.5 4.3 17.6 4.4 8.5 4.8 13.5 24.7 4.8 0.0 682.7 11.1 0.5 13.0 42.3 11.2 1.3 10.1 14.3 12.5 0.4 3.3 14.2 13.2 10.2 3.1 1.4 6.8 9.6 0.6 3.6 180.8 0.0 27.2 0.0 111.1 11.0 4.8 3.7 10.1 15.7 13.4 5.7 7.9 9.4 1.5 0.0 6.9 6.2 0.7 4.2 6.2 1.4 0.3 0.7 11.3 8.0 8.5 CD1C CD1 ENSG00000158481 "CD1c molecule" P29017 1 158289923-158294774 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "lymphoid tissue: 130.4" "Cell type enriched" "Detected in some" 6 "Langerhans cells: 551.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory B-cell: 84.1;myeloid DC: 324.9" "Group enriched" "Detected in many" 8 "B-cells: 84.1;dendritic cells: 324.9" "Group enriched" "Detected in some" 10 "JURKAT: 14.8;MOLT-4: 49.4" HPA068359 Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA 200000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "Endoplasmic reticulum" "HPA068359: " "unprognostic (2.55e-3)" "prognostic favorable (1.79e-5)" "unprognostic (1.75e-5)" "unprognostic (3.09e-5)" "unprognostic (3.12e-2)" "unprognostic (8.13e-3)" "unprognostic (2.01e-1)" "unprognostic (3.80e-3)" "unprognostic (7.11e-3)" "unprognostic (1.87e-1)" "unprognostic (7.41e-2)" "unprognostic (1.93e-1)" "unprognostic (1.04e-1)" "unprognostic (1.46e-1)" "unprognostic (1.67e-1)" "unprognostic (8.05e-2)" "unprognostic (1.99e-1)" 2.7 0.8 0.0 17.3 0.0 1.1 5.0 0.0 0.2 2.3 0.0 3.4 2.0 2.4 0.6 4.5 1.8 7.7 2.0 0.0 0.0 1.2 4.1 6.5 26.2 0.0 0.0 0.9 0.7 0.6 0.2 0.1 0.0 1.8 9.4 0.0 2.8 1.3 1.0 12.2 12.0 3.1 0.0 23.0 3.7 0.9 0.0 130.4 0.7 1.1 38.2 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 49.4 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.9 0.0 0.6 26.8 0.1 0.1 24.7 0.3 84.1 0.1 0.0 324.9 49.1 0.2 0.0 1.1 4.1 3.7 1.5 0.5 15.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.2 0.0 26.6 13.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 4.1 0.0 0.1 1.5 0.0 0.8 0.0 0.0 0.1 1.4 0.0 0.0 3.8 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 7.1 551.4 4.5 0.0 91.2 19.6 0.0 11.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 1.5 0.0 0.0 0.2 0.4 0.1 0.3 0.0 7.4 0.0 1.9 0.0 0.0 0.0 CD63 "ME491, MLA1, TSPAN30" ENSG00000135404 "CD63 molecule" P08962 12 55725323-55729707 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1857.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 4897.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010088, CAB026356, HPA073506" Supported Supported Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB026356: AB_629864, HPA010088: AB_1846323, HPA073506: " "unprognostic (8.76e-3)" "unprognostic (8.81e-2)" "unprognostic (1.27e-1)" "unprognostic (1.28e-3)" "unprognostic (9.48e-2)" "unprognostic (3.66e-3)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.11e-1)" "unprognostic (6.50e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-2)" "unprognostic (3.10e-1)" "unprognostic (2.70e-2)" "unprognostic (4.82e-2)" "unprognostic (5.21e-2)" "unprognostic (1.85e-3)" "unprognostic (9.02e-2)" 954.0 882.1 509.4 457.9 526.5 747.2 769.6 532.6 717.1 715.6 611.8 809.3 394.5 854.6 1492.1 396.1 647.3 607.0 1152.2 508.5 565.7 625.3 565.1 882.2 325.0 564.7 539.9 645.9 830.1 524.7 486.6 588.0 544.3 520.0 736.0 269.1 871.6 547.4 919.3 410.0 559.3 744.5 534.9 597.7 790.8 224.3 583.6 193.3 657.7 587.4 284.9 835.3 539.7 561.7 481.0 669.0 432.6 430.8 4897.7 2932.4 577.5 1914.8 3104.6 979.2 1048.9 750.3 939.2 120.5 581.2 2608.7 787.7 436.3 301.7 732.6 1197.9 372.5 248.7 760.9 542.8 443.3 2006.7 338.5 1699.0 2315.1 639.7 1164.8 979.2 2305.1 1052.2 64.6 386.8 936.3 3062.5 626.3 64.1 439.5 395.7 1062.7 880.7 146.0 949.3 345.7 1699.3 1433.6 170.1 425.8 528.3 392.5 3348.6 630.4 546.4 1089.6 948.0 710.1 514.8 984.9 649.8 377.3 239.3 92.5 2023.9 208.1 1326.3 1279.9 610.3 1857.5 323.2 458.8 235.2 111.0 126.9 260.0 473.0 73.9 55.9 186.0 656.0 733.0 320.4 309.8 121.6 850.4 509.4 526.5 532.6 717.1 508.5 565.7 564.7 539.9 544.3 534.9 583.6 561.7 798.7 512.8 689.0 28.1 147.6 567.2 1382.5 3135.4 155.4 190.3 606.5 601.1 820.9 836.4 1789.7 875.4 152.2 608.3 322.0 1083.4 232.8 2621.2 16.7 446.7 766.7 916.3 581.1 97.0 8.8 3429.0 2756.5 1538.0 371.1 727.3 1030.0 531.6 739.6 423.9 3372.5 33.7 9.3 1251.6 1715.1 854.6 1698.3 65.5 1727.3 1146.7 1993.9 11.2 575.7 893.8 487.1 21.1 26.5 3437.4 1394.0 1157.0 326.9 2039.2 878.1 794.2 1012.6 258.8 1255.6 1845.2 1278.7 43.8 68.9 137.1 400.5 2708.1 310.4 645.8 761.6 1868.9 CD68 "DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 358.0;lymphoid tissue: 370.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1820.4;Kupffer cells: 701.2;Langerhans cells: 341.5;Macrophages: 791.2;Proximal enterocytes: 335.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3255.5;intermediate monocyte: 3655.9;non-classical monocyte: 3740.6" "Group enriched" "Detected in all" 11 "dendritic cells: 1378.6;monocytes: 3740.6" "Cell line enhanced" "Detected in all" "ASC diff: 472.0;U-87 MG: 751.0" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" 139.6 78.3 10.4 236.1 9.8 266.2 72.6 11.2 33.4 77.8 14.6 88.8 279.5 26.7 9.0 126.4 43.1 161.1 38.9 8.2 26.7 50.6 156.7 358.0 217.3 45.5 31.2 19.4 22.1 14.2 8.9 173.1 36.0 13.1 91.9 4.8 52.6 19.8 23.0 24.8 240.2 79.0 16.1 370.7 87.5 15.2 58.5 44.2 22.7 21.3 84.2 149.3 50.6 31.6 243.4 48.6 3.2 3.5 472.0 177.6 2.1 75.6 203.9 97.8 113.4 10.1 71.3 2.9 84.2 220.8 174.6 10.6 1.2 47.6 65.9 2.2 9.0 38.8 13.2 59.0 42.0 19.2 207.8 57.1 9.8 205.4 150.4 162.6 26.3 4.3 15.7 24.2 95.5 2.2 1.7 17.2 2.8 63.1 36.0 3.3 4.5 144.4 20.9 10.9 1.6 3.0 63.2 31.3 72.1 2.2 1.6 146.1 82.4 123.7 8.0 125.7 100.1 1.4 2.1 1.9 751.0 46.4 64.0 243.5 3255.5 21.4 9.1 3655.9 11.1 80.2 4.1 6.2 817.3 59.0 5.8 5.1 219.4 18.7 3740.6 1378.6 6.5 3324.3 10.4 9.8 11.2 33.4 8.2 26.7 45.5 31.2 36.0 16.1 58.5 31.6 10.4 0.0 19.7 1.3 20.5 15.7 39.0 58.8 3.4 0.2 7.2 9.8 0.0 12.8 53.2 5.5 0.0 8.9 110.3 22.5 5.9 82.1 0.8 8.3 11.3 15.9 4.9 6.6 0.3 156.8 58.1 45.6 29.6 18.7 43.6 0.9 16.4 23.9 1820.4 0.0 0.4 15.8 16.2 701.2 341.5 2.1 6.5 791.2 39.2 5.6 179.2 0.3 7.2 0.0 0.1 121.0 86.1 1.9 8.5 33.3 335.3 50.2 20.6 1.0 26.3 8.7 11.7 0.5 1.2 12.4 14.3 33.4 10.8 0.5 28.9 99.9 CHGA ENSG00000100604 "Chromogranin A" P10645 14 92923150-92935285 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 6568.4" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 6553.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 114.8" "Group enriched" "Detected in many" 16 "cerebral cortex: 326.0;white matter: 124.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 151 "SCLC-21H: 489.5;SH-SY5Y: 1339.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000023, HPA017369, CAB040544, CAB055506, CAB058688" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 295000000 100000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "CAB000023: , CAB040544: , CAB055506: AB_2081135, CAB058688: AB_2665574, HPA017369: AB_1846698" "prognostic favorable (7.85e-5)" "unprognostic (4.89e-2)" "unprognostic (5.96e-2)" "unprognostic (1.17e-1)" "unprognostic (1.43e-2)" "unprognostic (5.95e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.74e-1)" "unprognostic (2.23e-1)" "unprognostic (4.56e-2)" "prognostic favorable (4.07e-4)" "unprognostic (1.85e-1)" "unprognostic (8.81e-13)" "unprognostic (1.07e-2)" "unprognostic (1.77e-1)" "unprognostic (9.17e-2)" "prognostic unfavorable (3.99e-4)" 14.5 1248.5 8.6 9.4 11.4 0.2 0.3 0.0 326.0 8.3 0.0 92.0 242.7 0.4 0.3 1.0 1.1 0.2 0.2 4.4 1.7 1.0 0.4 1.6 0.1 14.4 0.0 0.2 102.5 6568.4 446.2 0.0 4.1 12.2 105.2 11.0 0.2 0.3 0.1 0.6 179.9 0.9 0.0 0.1 364.5 77.7 4.3 0.6 24.6 0.0 0.0 1.3 1.2 124.4 0.0 0.5 2.4 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.8 2.7 0.0 0.0 0.2 0.0 1.4 0.0 0.0 489.5 1339.4 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 4.2 0.3 0.4 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 11.4 0.0 326.0 4.4 1.7 14.4 0.0 4.1 0.0 4.3 124.4 0.1 0.0 0.0 11.1 1.0 0.9 0.4 0.0 0.0 17.3 0.2 0.3 2.9 0.0 0.0 0.0 29.2 0.3 0.0 9.8 0.0 0.1 1.3 6.0 2.3 0.8 6553.1 0.0 59.5 0.4 0.1 4.1 195.7 0.5 0.0 0.5 0.0 0.0 1.5 16.8 37.7 820.4 14.2 0.0 0.0 7.9 39.7 0.1 7.2 15.9 2.0 3.7 0.0 10.6 12.8 46.5 137.8 137.3 0.0 6.6 36.7 0.0 0.0 16.2 0.0 0.0 0.2 4.7 2.2 0.0 0.0 0.3 0.2 0.4 25.9 5.1 CHPT1 CPT1 ENSG00000111666 "Choline phosphotransferase 1" Q8WUD6 12 101696947-101744140 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 344.4;Late spermatids: 650.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 36.9;eosinophil: 14.6" "Lineage enriched" "Detected in all" 8 "granulocytes: 36.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067643 Approved Supported Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA067643: " "unprognostic (1.59e-3)" "unprognostic (1.02e-1)" "unprognostic (1.91e-1)" "unprognostic (9.48e-2)" "unprognostic (3.15e-1)" "unprognostic (9.17e-2)" "unprognostic (5.79e-2)" "unprognostic (4.83e-2)" "unprognostic (1.12e-1)" "unprognostic (4.70e-1)" "unprognostic (5.27e-2)" "unprognostic (1.16e-2)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.72e-1)" "prognostic favorable (7.41e-4)" "unprognostic (1.79e-1)" 39.8 47.7 48.6 17.7 49.1 62.0 102.9 43.8 65.6 50.5 41.9 49.4 88.1 19.2 56.1 24.9 33.4 40.2 91.3 46.1 47.3 73.5 157.4 38.4 20.0 50.0 51.2 18.7 25.0 92.4 12.4 22.8 44.9 35.0 48.9 4.8 130.0 50.0 27.8 28.0 75.7 18.8 50.0 23.5 56.0 28.1 54.4 9.0 38.0 28.3 21.2 32.4 26.2 48.9 11.3 51.2 13.7 29.3 106.6 35.7 38.9 40.2 46.2 39.7 25.5 19.3 7.7 17.3 22.1 55.1 54.3 16.9 83.8 14.2 37.3 26.2 70.1 69.7 25.7 112.6 59.4 34.8 13.5 33.6 4.1 18.0 32.7 59.0 20.0 36.4 102.8 43.1 39.4 27.6 20.8 118.5 36.2 53.8 67.4 15.9 26.8 12.4 17.9 43.4 13.8 10.4 37.2 52.3 103.2 21.4 53.8 23.6 14.7 36.1 18.7 28.5 39.9 24.3 7.9 21.2 28.4 39.7 53.4 36.9 2.2 14.6 0.6 1.7 0.6 4.4 1.2 0.9 2.9 2.6 0.4 0.6 3.1 4.6 2.2 3.7 0.6 0.5 48.6 49.1 43.8 65.6 46.1 47.3 50.0 51.2 44.9 50.0 54.4 48.9 27.1 48.1 27.6 159.6 135.1 37.5 313.3 4.2 21.6 19.3 243.8 76.7 45.3 102.9 13.1 64.4 29.2 123.9 32.6 61.7 70.5 8.1 344.4 17.1 50.2 22.5 21.1 168.6 95.8 13.8 56.1 75.4 69.8 21.0 10.8 15.3 31.1 189.7 56.4 35.3 95.6 53.4 2.0 102.9 55.7 650.9 85.4 81.2 145.9 36.5 27.0 68.1 5.2 65.9 10.2 9.6 113.3 89.1 55.4 172.1 174.1 183.7 4.3 16.0 19.7 88.2 37.8 193.8 43.2 43.1 43.2 60.3 41.3 3.4 90.7 291.6 CLCN3 "ClC-3, CLC3" ENSG00000109572 "Chloride voltage-gated channel 3" P51790 4 169612633-169723673 "Predicted intracellular proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044723 Approved Supported Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA044723: AB_10959733" "unprognostic (1.92e-1)" "unprognostic (3.92e-2)" "unprognostic (1.95e-3)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (2.25e-1)" "unprognostic (3.32e-1)" "unprognostic (1.79e-1)" "unprognostic (5.40e-2)" "unprognostic (1.30e-1)" "prognostic favorable (1.10e-4)" "unprognostic (2.49e-2)" "unprognostic (2.49e-1)" "unprognostic (1.45e-1)" "unprognostic (6.38e-3)" 21.1 34.5 20.1 20.6 28.7 12.3 31.9 29.1 30.2 23.9 20.5 47.5 30.1 18.7 29.4 40.7 26.4 38.0 35.3 22.8 30.5 36.4 25.7 21.2 17.3 32.3 41.0 23.1 41.0 37.2 18.2 24.1 32.1 32.7 52.6 78.3 78.0 21.8 24.7 29.1 29.8 17.8 32.3 16.7 41.2 33.3 26.5 21.0 37.0 22.1 24.5 37.4 17.1 42.0 32.6 33.2 48.7 62.1 96.1 80.8 24.0 42.9 53.5 28.3 34.3 23.7 72.2 40.0 26.1 35.9 32.7 27.2 61.2 26.6 46.9 35.9 24.4 33.8 50.6 27.3 65.8 41.0 54.2 56.6 59.7 50.5 49.5 117.4 51.7 55.2 85.1 88.0 49.7 11.8 56.2 9.4 20.0 56.2 22.4 25.0 21.5 31.6 58.1 66.6 51.9 51.5 38.4 40.9 66.9 39.3 27.9 19.2 43.5 22.5 25.3 36.5 33.7 39.3 64.3 35.5 67.6 15.4 60.8 3.8 4.1 2.9 5.0 4.8 6.5 5.0 3.7 4.7 5.7 3.8 5.7 5.2 2.9 4.5 4.0 7.1 4.7 4.7 20.1 28.7 29.1 30.2 22.8 30.5 32.3 41.0 32.1 32.3 26.5 42.0 35.5 32.1 26.2 58.8 30.7 11.3 25.7 21.5 20.5 90.3 54.6 27.9 66.5 42.9 25.3 62.5 131.3 23.8 23.1 118.3 7.9 37.2 88.1 46.9 35.9 35.2 66.9 83.1 102.4 44.3 18.7 29.5 51.5 51.8 113.0 32.3 38.6 39.3 18.6 60.6 126.1 64.2 20.3 32.9 9.8 67.4 24.5 47.8 32.0 44.0 17.1 136.7 28.8 139.7 141.5 31.9 55.3 21.1 21.4 45.3 37.1 17.9 67.8 115.1 6.6 34.6 21.5 17.2 15.5 42.8 26.1 71.1 21.0 67.0 65.4 34.0 CLINT1 "CLINT, ENTH, EPNR, KIAA0171" ENSG00000113282 "Clathrin interactor 1" Q14677 5 157785743-157859145 "Plasma proteins, Predicted intracellular proteins, Transporters" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "basophil: 749.5" "Lineage enriched" "Detected in all" 10 "granulocytes: 749.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043280, HPA056947" Supported Supported Nucleoplasm,Vesicles NA NA 540000 "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Vesicles Nucleoplasm "HPA043280: AB_10793944, HPA056947: AB_2683283" "unprognostic (1.92e-2)" "unprognostic (6.93e-2)" "prognostic favorable (2.95e-4)" "unprognostic (7.23e-2)" "unprognostic (1.55e-1)" "unprognostic (2.79e-1)" "unprognostic (2.53e-1)" "unprognostic (8.13e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-2)" "unprognostic (4.89e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.88e-5)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (6.77e-4)" "unprognostic (3.56e-1)" 28.6 34.4 10.3 42.8 11.9 101.1 31.4 10.6 14.8 36.4 17.7 53.9 68.3 26.4 54.2 72.0 37.8 61.4 34.2 11.8 12.7 70.4 89.5 36.3 49.4 11.8 11.9 26.9 49.3 113.2 17.8 47.1 11.4 29.5 53.4 16.0 50.8 42.4 53.1 39.7 55.7 31.9 11.0 31.0 69.2 20.3 12.4 50.7 56.0 41.0 73.8 64.5 38.8 11.4 65.6 91.7 64.3 59.8 86.3 71.0 91.6 89.7 87.5 83.4 115.9 128.7 100.0 121.3 100.3 82.6 112.0 95.8 87.1 100.4 120.7 57.9 70.4 80.6 80.4 65.2 85.5 112.9 105.6 52.5 75.6 94.7 105.6 53.6 80.0 69.6 70.6 66.1 69.9 56.7 88.7 60.5 67.8 63.6 93.9 78.8 96.9 103.0 84.8 115.4 56.6 62.1 64.5 111.7 87.4 81.2 76.4 78.0 83.7 74.6 56.3 69.5 89.4 76.1 77.9 154.4 61.0 126.2 67.5 749.5 46.5 179.7 43.6 49.2 75.2 47.5 41.4 43.7 62.7 46.2 35.9 38.8 17.6 58.6 53.4 48.5 66.2 53.1 10.3 11.9 10.6 14.8 11.8 12.7 11.8 11.9 11.4 11.0 12.4 11.4 68.6 60.9 132.9 25.1 76.0 57.1 83.7 69.4 80.2 21.6 74.4 44.2 103.9 105.8 137.8 68.0 8.4 45.1 73.8 73.5 95.9 93.4 4.1 116.5 82.4 52.8 54.5 54.9 31.9 64.0 71.9 71.8 119.3 141.9 84.7 40.2 21.0 86.8 30.5 11.8 29.0 78.9 38.7 42.9 87.8 5.6 47.2 73.0 35.6 28.1 94.1 25.5 73.2 39.2 31.4 53.7 62.6 28.6 158.3 92.5 50.3 94.5 148.5 19.0 39.5 67.2 61.9 44.2 40.2 156.3 78.3 68.3 65.5 82.0 99.0 271.5 CLTB Lcb ENSG00000175416 "Clathrin light chain B" P09497 5 176392501-176416539 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 1839.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 704.2;MCF7: 641.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003692, HPA036458" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "Plasma membrane, Cytosol" "CAB003692: AB_425372, HPA036458: AB_2675136" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (4.51e-2)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" "unprognostic (3.54e-3)" "unprognostic (1.83e-2)" "unprognostic (1.74e-2)" "unprognostic (1.93e-1)" "unprognostic (7.42e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (7.89e-5)" "unprognostic (3.55e-1)" "unprognostic (7.50e-2)" "unprognostic (8.59e-2)" "unprognostic (1.60e-2)" 102.9 133.6 125.8 50.1 125.1 40.6 82.9 117.8 176.7 180.4 125.3 133.9 92.3 85.9 23.2 473.7 82.4 34.1 320.8 130.8 129.6 90.4 82.5 96.5 32.9 136.9 122.8 107.2 68.2 70.1 112.8 57.5 138.1 88.1 45.5 37.9 128.6 44.4 322.5 453.1 99.7 41.2 114.5 68.7 123.3 38.9 127.9 43.7 69.5 120.8 58.5 106.2 300.8 133.6 229.1 107.6 29.9 128.2 65.7 49.2 244.4 286.3 110.9 178.6 127.0 140.3 103.9 49.6 165.0 130.2 71.8 213.3 51.4 704.2 69.7 341.7 95.3 33.6 163.3 87.7 102.9 53.2 85.6 52.6 241.5 98.1 114.7 36.0 84.7 39.2 65.2 123.4 100.3 641.9 84.5 81.1 24.4 189.5 158.2 91.3 52.9 165.2 95.6 92.0 127.7 43.7 136.6 148.0 103.6 34.7 61.4 101.9 185.2 64.0 96.3 117.5 165.1 96.5 73.3 68.5 51.4 112.7 74.4 6.6 19.7 61.7 13.6 15.8 7.0 5.9 11.9 13.2 20.0 10.1 10.0 10.0 36.6 15.0 20.8 16.1 24.9 8.1 125.8 125.1 117.8 176.7 130.8 129.6 136.9 122.8 138.1 114.5 127.9 133.6 113.7 57.7 19.8 8.5 54.7 634.0 238.7 155.7 180.4 310.5 105.5 124.6 208.5 72.9 93.4 82.8 64.6 141.1 82.3 794.5 135.0 324.7 9.5 58.4 72.7 102.2 151.8 43.6 25.4 453.1 586.9 136.7 193.2 85.2 48.2 40.8 70.3 96.3 111.9 336.5 24.1 348.5 114.0 80.7 226.1 13.7 122.1 88.4 220.5 6.5 85.7 136.1 107.1 8.0 15.2 1839.9 786.9 129.8 76.4 391.4 545.7 269.7 49.6 64.3 78.9 79.6 161.4 15.9 29.1 415.6 803.0 386.5 81.3 151.2 289.7 436.0 CLUH "CLU1, KIAA0664" ENSG00000132361 "Clustered mitochondria homolog" O75153 17 2689386-2712663 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 122.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CACO-2: 266.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031505, HPA044346" Uncertain Supported "Nuclear bodies,Vesicles" NA NA 5500 "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Nuclear bodies" "HPA031505: AB_2673912, HPA044346: AB_10962153" "unprognostic (3.48e-2)" "unprognostic (3.97e-2)" "unprognostic (9.02e-2)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (1.15e-2)" "unprognostic (2.85e-2)" "unprognostic (2.84e-2)" "unprognostic (1.84e-1)" "unprognostic (2.69e-2)" "unprognostic (5.64e-2)" "unprognostic (5.11e-2)" "prognostic favorable (1.92e-5)" "unprognostic (4.99e-2)" "unprognostic (1.25e-1)" "unprognostic (1.92e-2)" "unprognostic (6.26e-2)" 30.8 56.7 13.8 18.1 12.7 14.3 28.5 16.3 18.3 19.8 19.7 45.9 46.6 21.3 1.9 67.7 19.2 15.4 80.8 14.5 11.2 50.6 135.0 19.6 14.6 14.6 13.2 17.0 50.4 15.6 20.3 9.0 15.3 24.7 13.2 7.2 32.1 11.8 127.8 47.5 34.2 8.5 9.3 25.2 35.1 25.2 17.3 6.4 25.2 52.9 11.1 29.6 29.2 11.2 69.5 131.9 8.9 33.3 20.2 14.1 99.9 34.9 13.0 41.9 31.0 266.2 30.0 122.6 41.5 19.4 26.9 127.6 45.3 52.9 14.7 43.6 86.4 68.0 112.2 93.9 17.1 53.7 44.1 22.6 29.7 48.9 24.7 9.4 20.5 43.3 81.8 42.2 11.7 79.8 69.6 58.0 28.2 35.8 67.8 104.7 37.0 70.8 26.0 117.3 43.9 32.6 40.0 129.4 44.4 6.6 72.7 31.3 33.7 33.7 44.9 92.2 80.5 18.2 22.9 49.7 35.4 73.2 41.6 0.0 2.2 0.0 1.7 3.1 1.3 2.2 1.0 0.9 2.4 2.2 2.3 2.1 0.2 0.6 2.0 2.7 1.5 0.9 13.8 12.7 16.3 18.3 14.5 11.2 14.6 13.2 15.3 9.3 17.3 11.2 5.8 6.4 20.9 20.9 6.5 30.5 12.0 11.7 16.5 18.5 23.5 22.7 42.1 41.5 16.7 18.4 22.9 9.7 7.6 47.8 11.7 18.4 1.8 12.7 10.8 8.5 25.8 22.1 9.9 18.3 8.2 6.8 22.4 24.6 1.3 18.1 6.8 122.1 13.1 8.4 11.4 38.8 14.2 10.3 6.3 4.0 5.0 7.9 21.4 4.7 7.4 6.5 2.1 7.5 6.2 19.6 21.2 6.0 11.7 22.9 39.2 35.1 14.1 17.1 6.6 12.3 11.3 8.6 17.5 42.4 35.5 8.2 7.2 43.3 68.3 22.5 CNGB1 "CNCG2, CNCG3L, CNGB1B, GAR1, GARP, RCNC2, RCNCb, RP45" ENSG00000070729 "Cyclic nucleotide gated channel subunit beta 1" Q14028 16 57882340-57971128 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Olfaction, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "retina: 600.2" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 331.5;Rod photoreceptor cells: 1111.1" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.5;RPMI-8226: 1.8;SCLC-21H: 5.0;SiHa: 2.9;SK-BR-3: 1.4" "Region enhanced" "Detected in some" "hypothalamus: 4.5" "HPA039159, HPA060355" Approved Vesicles,Cytosol No NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol Vesicles "HPA039159: AB_10795579, HPA060355: " "unprognostic (5.52e-3)" "unprognostic (4.51e-3)" "unprognostic (1.06e-1)" "unprognostic (2.73e-3)" "unprognostic (6.20e-2)" "unprognostic (1.76e-1)" "unprognostic (8.56e-4)" "unprognostic (3.08e-1)" "unprognostic (9.84e-2)" "unprognostic (2.83e-1)" "unprognostic (2.14e-4)" "unprognostic (5.42e-2)" "unprognostic (1.01e-3)" "unprognostic (5.20e-2)" "unprognostic (1.88e-1)" "unprognostic (4.57e-2)" "unprognostic (9.07e-2)" 0.1 2.5 15.5 1.1 13.2 0.2 0.0 0.0 20.4 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.1 0.3 0.0 24.5 24.8 0.0 0.1 0.1 0.2 2.8 3.2 0.0 0.5 0.0 0.2 0.4 4.4 0.0 0.4 600.2 0.0 0.1 0.0 0.2 0.6 0.1 2.4 0.1 0.0 0.4 36.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.5 0.0 0.5 0.0 0.0 1.3 0.0 0.1 0.0 0.3 0.9 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 1.8 0.0 0.6 5.0 0.0 2.9 1.4 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.2 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 15.5 13.2 0.0 20.4 24.5 24.8 2.8 3.2 4.4 2.4 36.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.4 0.0 61.6 0.3 0.0 1.1 0.0 0.1 0.0 331.5 6.9 0.0 0.0 0.0 0.4 1.6 0.9 0.1 4.2 0.0 0.0 3.2 0.4 0.9 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.4 25.2 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 89.5 0.0 1.0 0.1 0.2 1.1 0.0 0.0 0.2 0.0 0.3 0.0 1111.1 0.0 0.1 0.2 0.5 0.7 0.0 0.0 1.4 0.1 0.1 0.0 0.2 CNST "C1orf71, FLJ32001, PPP1R64" ENSG00000162852 "Consortin, connexin sorting protein" Q6PJW8 1 246566444-246668595 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007225, HPA007226" Approved Supported Vesicles NA NA 480000 "Cluster 37: B-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Vesicles "HPA007225: AB_1848869, HPA007226: AB_2667782" "unprognostic (1.55e-2)" "unprognostic (9.75e-2)" "unprognostic (3.33e-2)" "unprognostic (9.76e-2)" "unprognostic (2.78e-1)" "unprognostic (4.28e-2)" "unprognostic (3.72e-2)" "unprognostic (7.28e-3)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (3.52e-2)" "unprognostic (3.47e-2)" "unprognostic (2.73e-3)" "unprognostic (6.17e-2)" "unprognostic (2.63e-1)" "unprognostic (8.77e-3)" "unprognostic (2.26e-1)" 13.1 19.2 8.8 10.5 9.7 23.5 10.9 14.4 16.1 9.0 17.1 13.7 10.2 9.0 8.1 16.7 8.8 8.7 8.9 10.3 11.1 8.6 23.5 9.9 16.7 6.9 7.8 10.5 10.2 11.3 7.5 9.3 8.4 8.1 12.0 16.8 7.2 7.3 31.8 10.1 13.2 10.1 5.6 10.4 8.4 12.9 7.6 14.3 13.9 39.0 13.4 11.3 8.8 9.5 8.4 11.0 7.9 7.0 12.8 14.7 16.0 26.9 26.5 26.7 20.2 10.5 10.9 24.6 11.7 26.9 7.9 8.6 12.3 9.2 36.2 13.8 4.2 28.9 10.4 8.0 18.4 14.5 53.5 14.0 8.7 25.9 27.4 13.2 8.4 13.0 37.3 10.5 15.3 6.1 15.9 6.7 25.9 11.7 9.5 15.5 14.2 20.1 10.1 24.4 18.0 21.6 11.5 6.7 34.0 9.2 12.3 12.6 12.0 33.0 7.9 13.8 18.5 31.8 43.8 25.0 8.1 21.2 32.5 47.1 8.1 23.9 14.4 8.8 16.1 35.6 24.8 13.6 8.1 35.7 31.1 16.9 10.7 15.1 22.2 11.7 33.2 15.9 8.8 9.7 14.4 16.1 10.3 11.1 6.9 7.8 8.4 5.6 7.6 9.5 41.3 12.8 17.2 21.2 46.0 24.9 21.5 6.7 27.3 31.5 10.2 7.5 14.3 12.8 17.7 3.7 14.6 4.0 18.2 46.9 7.9 6.9 44.7 43.7 17.2 29.0 15.0 25.2 58.5 6.0 6.2 22.5 16.3 68.3 40.4 8.1 30.0 22.1 10.0 16.8 54.1 19.3 10.2 12.5 12.2 41.6 9.6 32.9 14.2 22.5 10.1 14.9 18.6 43.2 35.7 8.8 31.4 7.9 26.4 16.4 42.7 5.9 23.4 24.4 13.1 20.6 29.2 16.7 13.1 20.6 26.9 9.3 31.7 8.3 14.3 23.3 COCH "COCH-5B2, DFNA31, DFNA9" ENSG00000100473 Cochlin O43405 14 30874514-30895065 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "pancreas: 502.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 63.0;Horizontal cells: 84.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 71.3" "Group enriched" "Detected in some" 12 "memory B-cell: 38.3;naive B-cell: 17.7" "Lineage enriched" "Detected in many" 17 "B-cells: 38.3" "Cell line enhanced" "Detected in many" "HEK 293: 95.7;Hep G2: 63.8;K-562: 129.1;NB-4: 105.5;SCLC-21H: 111.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 50.8" HPA065086 Supported Vesicles "Secreted in other tissues" NA NA 160000 "Cluster 19: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 1: K-562 - Erythropoiesis" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA065086: " "unprognostic (8.36e-3)" "unprognostic (2.51e-2)" "unprognostic (8.61e-2)" "unprognostic (1.64e-2)" "unprognostic (6.48e-2)" "unprognostic (6.53e-2)" "unprognostic (9.61e-2)" "unprognostic (4.03e-1)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" "unprognostic (1.27e-2)" "unprognostic (2.91e-3)" "unprognostic (5.42e-3)" "unprognostic (3.92e-2)" "unprognostic (2.80e-2)" "unprognostic (1.03e-1)" "unprognostic (1.72e-1)" 3.2 3.7 7.3 2.8 71.3 4.0 3.4 1.4 20.9 17.4 19.0 3.2 0.8 0.6 2.2 0.9 6.2 2.9 1.9 5.6 8.0 5.2 0.5 0.6 11.0 2.9 7.9 0.8 502.0 3.4 10.1 1.9 3.7 48.3 2.2 12.1 3.6 73.4 1.3 15.2 2.6 1.1 6.2 2.6 1.7 5.2 12.5 1.3 1.3 5.0 7.7 2.0 23.0 1.7 0.0 35.3 3.1 0.0 0.6 0.1 21.8 0.2 0.0 6.4 17.1 20.9 1.2 0.4 1.7 0.0 1.3 0.1 22.2 0.0 10.6 0.0 95.7 18.1 7.6 63.8 0.0 1.8 7.3 1.3 0.0 0.6 0.0 0.0 0.3 39.9 129.1 5.1 1.6 0.8 9.2 105.5 11.9 0.1 3.7 26.7 0.0 0.9 1.1 3.4 111.8 30.4 2.6 0.6 0.2 12.1 0.0 48.7 0.9 0.0 0.0 0.3 0.1 5.7 15.8 11.2 0.0 0.0 4.7 0.0 0.6 0.0 0.0 0.0 0.0 38.3 0.3 0.0 0.1 17.7 0.0 0.1 0.2 0.0 0.0 0.0 2.2 1.0 7.3 71.3 1.4 20.9 5.6 8.0 2.9 7.9 3.7 6.2 12.5 1.7 2.0 0.0 0.5 3.6 13.4 19.1 2.3 0.3 0.0 2.7 7.9 1.5 0.8 2.8 0.9 0.0 4.2 6.5 1.3 0.6 1.9 0.5 1.5 2.2 0.8 3.1 17.0 7.4 14.3 63.0 14.3 22.0 1.1 1.0 1.3 1.8 5.0 5.0 3.8 84.1 24.2 0.3 6.1 5.0 25.2 2.0 1.5 2.4 19.6 7.5 2.8 14.5 0.0 6.0 16.5 3.7 4.3 6.0 10.0 3.5 0.2 11.7 0.5 4.0 0.0 2.8 9.0 22.1 20.3 0.1 13.5 6.6 3.3 0.1 0.6 1.7 COL22A1 ENSG00000169436 "Collagen type XXII alpha 1 chain" Q8NFW1 8 138588235-138914041 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pituitary gland: 44.0" "Cell type enhanced" "Detected in some" "Early spermatids: 39.6;Excitatory neurons: 13.0;Late spermatids: 33.7;Muller glia cells: 25.5" "Cancer enhanced" "Detected in many" "testis cancer: 9.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 29.5;RT4: 12.2;SCLC-21H: 8.1;U-2 OS: 6.8" "Low region specificity" "Detected in many" HPA024830 Enhanced Supported "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum" "HPA024830: AB_1847102" "unprognostic (1.06e-1)" "unprognostic (1.31e-1)" "unprognostic (2.88e-2)" "unprognostic (4.19e-6)" "prognostic unfavorable (4.15e-4)" "unprognostic (1.05e-2)" "unprognostic (5.57e-3)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.01e-1)" "unprognostic (9.24e-2)" "unprognostic (5.74e-2)" "unprognostic (3.62e-2)" "unprognostic (3.66e-15)" "unprognostic (2.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "unprognostic (1.09e-1)" 0.1 7.6 0.6 0.6 1.0 0.0 0.0 2.9 0.5 0.8 0.4 1.0 0.3 1.9 0.2 0.1 0.4 0.3 0.2 0.3 1.4 1.9 0.0 0.0 0.5 2.9 1.2 0.2 0.1 1.4 44.0 0.0 0.6 3.0 0.1 5.2 0.9 2.4 0.7 0.0 0.4 1.6 4.3 0.2 2.2 1.1 2.0 2.1 0.2 1.1 1.2 0.9 0.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 12.2 8.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 2.9 0.5 0.3 1.4 2.9 1.2 0.6 4.3 2.0 2.3 0.0 0.0 0.0 0.3 0.0 0.0 3.7 2.5 0.0 0.3 0.2 0.3 1.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 39.6 0.1 0.2 0.8 0.0 0.0 13.0 0.2 0.0 0.2 0.0 0.6 0.0 0.6 0.0 0.0 5.9 0.0 0.8 0.0 8.2 0.0 0.0 33.7 0.3 0.3 0.0 1.0 0.6 25.5 0.0 0.5 0.3 3.0 0.0 0.0 0.0 4.8 0.0 0.1 0.2 1.6 0.0 0.1 0.3 2.1 1.7 0.0 0.0 0.0 0.0 0.0 0.1 1.9 COL4A2 "DKFZp686I14213, FLJ22259" ENSG00000134871 "Collagen type IV alpha 2 chain" P08572 13 110305812-110513209 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 474.0" "Cell type enhanced" "Detected in many" "Adipocytes: 313.6;Endometrial stromal cells: 308.3;Endothelial cells: 278.2;Extravillous trophoblasts: 512.9;Granulosa cells: 223.8;Sertoli cells: 374.7;Smooth muscle cells: 338.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 1041.3;WM-115: 428.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010751, HPA029118, HPA069337" Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA 2700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB010751: AB_476828, HPA029118: , HPA069337: " "unprognostic (2.43e-1)" "unprognostic (4.13e-3)" "unprognostic (8.04e-2)" "unprognostic (6.03e-3)" "unprognostic (2.20e-1)" "unprognostic (2.64e-2)" "unprognostic (3.45e-2)" "unprognostic (1.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.33e-2)" "unprognostic (1.57e-2)" "unprognostic (6.95e-2)" "prognostic unfavorable (9.25e-4)" 240.5 51.2 15.1 103.5 2.3 0.6 153.5 1.7 5.9 111.6 3.4 282.0 29.5 219.4 10.4 51.8 122.9 84.2 113.0 19.3 1.8 71.7 19.1 181.7 22.8 4.3 7.8 51.9 32.6 25.6 17.5 474.0 6.0 121.3 18.9 2.8 35.0 95.8 44.7 45.2 84.1 226.8 2.6 121.5 96.4 15.7 11.5 7.9 74.9 21.5 7.1 186.2 74.4 2.9 88.9 45.7 218.7 0.6 213.7 99.0 312.8 307.9 97.4 167.3 76.1 2.5 0.7 0.6 1041.3 60.0 75.0 85.4 0.1 82.4 27.3 28.1 46.3 0.2 76.6 0.7 150.5 0.5 1.0 42.8 4.5 114.8 71.2 193.5 158.5 0.0 1.3 0.9 25.4 0.3 0.3 12.1 34.2 0.8 11.7 0.6 87.8 0.4 125.6 0.0 6.4 35.4 0.3 0.9 81.2 84.7 0.6 6.7 327.7 94.9 237.9 2.3 161.9 0.6 3.0 7.4 5.8 0.4 428.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 2.3 1.7 5.9 19.3 1.8 4.3 7.8 6.0 2.6 11.5 2.9 313.6 83.3 5.8 17.9 2.9 9.6 8.0 16.3 1.8 2.4 7.0 56.8 31.8 20.0 1.8 53.3 0.0 77.4 0.1 10.0 1.9 39.0 1.7 19.4 308.3 278.2 0.0 8.0 17.7 4.4 512.9 159.1 5.6 50.1 1.3 223.8 102.1 1.8 30.9 0.0 44.0 7.0 2.0 3.3 13.3 3.4 60.6 3.8 39.2 46.9 2.0 7.3 0.0 5.5 1.1 2.8 1.4 176.0 1.5 12.3 23.9 32.7 2.1 0.3 374.7 64.7 338.9 0.9 8.5 0.7 7.0 67.2 3.6 49.4 5.4 2.4 COL8A1 "C3orf7, MGC9568" ENSG00000144810 "Collagen type VIII alpha 1 chain" P27658 3 99638475-99799226 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Fibroblasts: 53.3;Hepatic stellate cells: 102.8;Smooth muscle cells: 51.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 34.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 1098.3;hTERT-RPE1: 431.9;LHCN-M2: 313.0;TIME: 471.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053107 Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA053107: AB_2682046" "unprognostic (3.13e-2)" "unprognostic (2.92e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-3)" "unprognostic (2.49e-1)" "unprognostic (2.31e-2)" "unprognostic (4.83e-2)" "unprognostic (2.62e-2)" "unprognostic (4.79e-2)" "unprognostic (3.58e-2)" "unprognostic (3.71e-1)" "prognostic unfavorable (9.39e-8)" "unprognostic (2.98e-3)" "unprognostic (1.72e-1)" "unprognostic (1.38e-2)" "unprognostic (1.32e-3)" 33.0 7.0 1.7 5.8 2.9 0.0 5.7 1.8 2.6 3.8 4.4 12.4 1.0 5.2 2.7 11.1 9.1 10.8 39.1 1.3 3.0 5.9 0.9 32.8 0.9 3.1 3.9 9.2 1.2 17.9 11.3 4.2 3.4 12.7 6.9 0.5 7.0 12.0 2.3 3.2 3.7 31.5 2.7 1.0 5.3 0.5 2.6 0.4 27.5 7.8 0.5 25.0 5.4 2.5 0.1 0.4 3.0 0.3 142.2 236.4 0.2 68.5 45.7 69.6 138.6 0.0 0.3 0.1 5.9 1098.3 1.9 0.1 0.4 88.2 157.8 0.1 0.2 0.1 7.9 0.0 26.8 0.0 0.1 142.8 3.2 52.6 82.9 431.9 129.4 0.0 0.1 0.2 313.0 0.0 0.0 0.0 2.6 0.0 0.9 0.0 0.0 0.0 144.3 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.1 0.2 471.5 31.0 24.1 1.6 34.2 0.1 0.0 0.1 58.4 0.0 241.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.9 1.8 2.6 1.3 3.0 3.1 3.9 3.4 2.7 2.6 2.5 4.4 246.8 22.1 0.0 0.4 0.8 0.5 2.8 14.8 0.4 1.8 5.2 4.9 4.3 3.9 9.2 0.0 0.1 0.9 0.0 0.0 0.1 1.3 0.2 2.6 14.1 0.0 0.0 1.9 0.0 0.3 53.3 2.0 0.3 5.1 0.2 102.8 0.8 0.1 0.0 0.7 0.0 0.0 1.9 2.3 1.0 2.1 0.8 1.8 4.7 0.2 0.7 2.1 9.0 0.6 0.1 0.0 9.4 0.5 0.2 0.0 1.6 1.0 0.6 0.0 1.9 51.6 0.3 0.3 1.0 0.6 0.4 0.9 0.1 0.0 0.5 COPB1 COPB ENSG00000129083 "COPI coat complex subunit beta 1" P53618 11 14443440-14500027 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012338, HPA043954, HPA064403" Supported Enhanced "Golgi apparatus,Vesicles,Cytosol" NA NA 330000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles, Cytosol" "CAB012338: AB_726922, HPA043954: AB_2678746, HPA064403: AB_2685258" "unprognostic (2.35e-1)" "unprognostic (1.02e-3)" "unprognostic (1.36e-2)" "unprognostic (4.76e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (6.91e-4)" "prognostic unfavorable (5.63e-7)" "unprognostic (4.69e-3)" "unprognostic (3.42e-2)" "unprognostic (3.60e-1)" "prognostic unfavorable (8.04e-4)" "unprognostic (8.94e-2)" "unprognostic (1.78e-2)" "unprognostic (3.02e-2)" "unprognostic (8.00e-2)" "unprognostic (3.87e-1)" "unprognostic (1.69e-2)" 48.1 47.1 19.9 55.0 21.8 79.8 62.6 26.2 25.3 64.9 44.7 59.8 57.7 52.6 69.3 46.7 49.2 54.9 43.7 20.1 23.6 65.3 73.6 49.9 59.1 24.2 21.8 49.1 59.2 67.6 48.4 69.2 23.7 66.9 67.1 39.3 67.5 53.8 33.1 36.6 58.8 61.1 23.5 46.3 59.7 46.8 23.0 68.1 81.0 38.1 64.5 60.4 40.0 27.6 134.9 113.6 118.6 89.4 193.1 221.3 95.9 199.2 206.5 173.1 202.0 89.1 203.5 130.1 87.1 252.9 164.6 144.7 134.6 133.3 212.1 122.7 114.0 138.3 74.3 135.8 171.3 128.9 134.4 156.3 172.4 116.0 217.8 158.9 183.7 71.6 104.5 103.8 221.1 101.6 117.2 78.7 61.7 163.3 123.1 94.9 163.1 89.0 156.1 123.3 75.6 81.2 154.2 123.2 104.8 135.5 112.3 110.1 189.5 166.2 85.4 181.3 110.1 55.2 100.5 143.8 125.1 79.2 158.6 52.8 38.7 43.5 45.7 47.8 55.7 38.4 38.1 47.6 52.3 32.0 37.8 39.8 31.2 44.6 49.8 31.1 44.8 43.2 19.9 21.8 26.2 25.3 20.1 23.6 24.2 21.8 23.7 23.5 23.0 27.6 55.6 109.0 63.2 29.0 64.3 38.9 59.7 82.6 52.3 28.4 43.0 27.9 31.3 35.8 107.8 44.1 27.1 65.4 71.2 55.9 41.1 77.1 17.2 72.6 81.4 55.5 43.8 50.9 36.9 81.7 69.6 70.5 63.2 72.5 65.2 50.7 51.4 58.1 60.9 18.5 39.1 87.5 61.1 50.7 43.5 10.7 51.0 61.5 21.4 35.6 70.1 34.0 44.3 32.6 49.6 93.6 37.5 55.3 107.4 54.3 60.6 57.3 131.9 29.5 52.6 60.8 78.7 87.5 64.3 48.7 35.8 117.0 77.0 49.3 51.5 60.7 COPS2 "ALIEN, CSN2, TRIP15" ENSG00000166200 "COP9 signalosome subunit 2" P61201 15 49106068-49155661 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016867, HPA018271, HPA061071" Approved Supported "Vesicles,Cytokinetic bridge" Yes No 190000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" Vesicles "Cytokinetic bridge" "HPA016867: AB_1858336, HPA018271: AB_1858335, HPA061071: AB_2684424" "unprognostic (3.47e-1)" "unprognostic (2.28e-2)" "unprognostic (1.66e-1)" "unprognostic (7.20e-2)" "unprognostic (1.86e-1)" "unprognostic (7.84e-3)" "unprognostic (1.04e-1)" "unprognostic (6.77e-2)" "unprognostic (2.49e-2)" "unprognostic (6.09e-2)" "unprognostic (3.86e-3)" "unprognostic (1.42e-1)" "unprognostic (4.35e-3)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (5.62e-2)" "unprognostic (1.10e-3)" 61.7 43.4 24.8 34.4 28.5 124.5 67.0 35.0 36.8 61.9 25.3 43.2 43.3 58.4 44.0 63.2 43.2 53.7 61.5 26.1 30.4 60.8 57.6 35.0 45.5 30.9 27.7 76.7 54.0 65.7 26.4 45.0 32.8 45.2 41.6 32.2 40.0 47.0 92.6 35.5 37.2 56.5 35.2 32.0 36.4 51.0 27.5 49.6 61.8 112.1 48.8 59.0 35.3 41.7 92.0 53.1 111.6 94.4 134.2 189.9 76.7 157.3 149.8 135.4 123.5 113.0 49.1 151.1 105.2 152.2 108.7 131.9 160.3 130.9 148.0 103.3 64.5 141.0 105.4 91.7 102.6 134.7 70.7 161.2 104.3 110.4 193.3 149.3 144.0 82.5 184.4 78.8 149.3 49.5 72.3 67.3 72.6 128.4 68.9 78.2 105.2 227.7 143.5 136.5 108.4 78.6 90.7 96.4 127.8 129.4 95.6 133.3 93.4 132.1 71.0 249.6 167.9 71.0 196.3 191.0 123.4 215.1 109.4 11.7 17.9 12.2 13.1 23.5 24.4 14.6 19.7 19.2 21.0 13.9 24.8 16.2 7.4 16.6 22.9 13.3 28.4 16.0 24.8 28.5 35.0 36.8 26.1 30.4 30.9 27.7 32.8 35.2 27.5 41.7 72.8 76.9 56.1 14.4 50.0 87.1 57.1 90.8 80.8 23.2 47.6 59.3 104.3 27.1 69.8 23.9 10.4 56.1 48.2 18.5 54.8 40.3 28.2 56.7 91.6 53.6 20.8 50.1 35.2 29.9 71.0 79.6 36.2 94.0 52.6 39.3 46.1 32.5 43.9 33.7 36.1 25.1 32.6 47.5 44.9 21.6 55.3 46.1 35.6 19.7 49.3 24.8 27.8 21.6 48.7 35.9 21.6 53.4 63.5 53.0 41.0 84.8 47.4 19.7 19.7 74.6 109.0 93.1 43.3 63.2 98.9 131.9 54.0 58.6 34.6 64.4 CPQ "LDP, PGCP" ENSG00000104324 "Carboxypeptidase Q" Q9Y646 8 96645242-97149654 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 225.9" "Cell type enhanced" "Detected in all" "Astrocytes: 150.2;Oligodendrocytes: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 250.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 116.1;ASC TERT1: 131.4;hTERT-RPE1: 108.2;Karpas-707: 97.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023235, HPA024490" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 51000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA023235: AB_1855257, HPA024490: AB_1855258" "unprognostic (4.04e-2)" "unprognostic (5.46e-2)" "unprognostic (4.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "unprognostic (3.98e-3)" "unprognostic (5.24e-2)" "unprognostic (2.92e-2)" "unprognostic (2.67e-2)" "unprognostic (9.19e-2)" "unprognostic (2.38e-3)" "unprognostic (6.16e-3)" "prognostic favorable (5.40e-5)" "unprognostic (6.74e-3)" "unprognostic (8.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.75e-1)" 46.2 35.9 22.6 25.4 33.9 31.8 34.7 28.0 26.7 75.1 20.6 39.6 29.3 46.0 36.2 25.9 39.8 57.8 51.8 21.6 27.0 80.5 70.0 32.3 22.8 32.6 27.5 87.4 46.7 60.7 25.6 39.2 33.2 40.2 33.1 16.8 32.8 54.2 13.3 20.6 35.0 64.7 25.9 31.3 32.1 13.9 30.3 8.2 225.9 33.2 17.0 46.3 38.6 38.6 0.6 2.1 2.1 0.1 116.1 131.4 0.5 35.3 55.6 12.8 26.5 2.0 0.9 0.4 27.2 59.0 15.7 1.0 2.4 2.8 12.0 31.4 4.4 28.4 1.5 17.7 25.6 4.9 37.0 69.6 6.5 15.0 3.7 108.2 6.0 0.1 27.1 97.0 29.4 1.2 0.5 14.1 2.5 0.2 5.2 4.3 0.0 0.6 26.7 13.2 2.4 0.3 10.2 0.4 28.2 25.8 12.3 28.6 21.3 51.9 4.9 0.8 11.5 7.9 0.9 0.3 32.2 21.6 33.5 32.0 71.3 45.1 27.3 49.6 27.6 5.4 20.3 24.0 51.8 7.4 17.6 24.6 250.5 25.9 47.5 14.8 22.2 40.6 22.6 33.9 28.0 26.7 21.6 27.0 32.6 27.5 33.2 25.9 30.3 38.6 46.6 12.8 12.5 150.2 11.7 19.4 25.7 21.3 9.6 12.7 12.1 27.9 27.2 42.9 13.9 47.8 29.2 12.1 40.8 9.3 17.6 22.7 5.0 6.6 43.3 27.1 13.8 7.2 24.0 10.7 1.8 123.8 10.7 8.6 38.0 43.1 51.0 48.3 54.0 10.1 31.3 7.9 24.4 56.0 44.9 9.0 72.4 39.4 78.2 131.2 33.7 43.4 39.1 44.7 299.6 11.7 9.5 73.0 11.9 12.4 42.4 56.0 9.7 16.3 52.6 71.1 67.8 5.6 3.4 2.8 13.1 6.0 23.8 38.6 12.2 13.5 CRP PTX1 ENSG00000132693 "C-reactive protein" P02741 1 159712289-159714589 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 79 "liver: 9388.5" "Group enriched" "Detected in some" 16 "Ductal cells: 1087.7;Hepatocytes: 4142.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 1010.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.3;HDLM-2: 6.3;U-2 OS: 4.5;U-266/84: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005036, HPA027367, HPA027396" Supported Approved "Nucleoplasm,Vesicles,Intermediate filaments" "Secreted to blood" NA NA 2920000000 5200000000 "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Vesicles" "Intermediate filaments" "CAB005036: AB_562362, HPA027367: AB_1847216, HPA027396: AB_1847217" "unprognostic (3.74e-1)" "unprognostic (5.31e-2)" "unprognostic (2.97e-2)" "unprognostic (1.27e-1)" "unprognostic (3.57e-2)" "unprognostic (1.33e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (4.17e-10)" "unprognostic (3.39e-2)" "unprognostic (3.48e-1)" "unprognostic (5.60e-2)" "unprognostic (6.61e-2)" 3.4 0.7 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.3 0.0 3.1 0.0 0.5 0.4 111.7 0.7 0.0 0.0 0.7 9388.5 0.5 0.1 0.0 0.0 0.4 118.5 0.0 0.3 0.1 0.0 0.6 0.0 0.0 0.4 0.0 0.3 0.6 0.5 0.0 0.0 6.1 0.4 0.4 0.0 0.0 0.3 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 0.0 0.0 0.0 6.3 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.1 0.8 0.0 11.7 1.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 118.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1087.7 1.4 0.0 0.1 6.3 0.0 163.2 0.0 63.2 0.0 0.0 0.0 0.2 0.0 0.0 89.6 4142.7 0.1 0.0 0.0 0.0 0.0 98.8 0.3 0.7 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 60.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 CST3 ENSG00000101439 "Cystatin C" P01034 20 23626706-23638473 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Age-related macular degeneration, Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 4217.6" "Cell type enriched" "Detected in all" 4 "Langerhans cells: 18746.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 4967.5;intermediate monocyte: 6424.5;myeloid DC: 7959.0;non-classical monocyte: 4297.7;plasmacytoid DC: 4427.4" "Group enriched" "Detected in all" 9 "dendritic cells: 7959.0;monocytes: 6424.5" "Cell line enhanced" "Detected in many" "ASC diff: 1733.4;ASC TERT1: 1179.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000118, HPA013143" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1040000000 2800000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "CAB000118: , HPA013143: AB_1847417" "unprognostic (3.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.53e-2)" "unprognostic (4.06e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.46e-2)" "unprognostic (3.72e-1)" "unprognostic (2.29e-3)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-1)" "unprognostic (5.01e-2)" "prognostic favorable (8.77e-4)" 1046.2 707.6 3041.2 262.3 3117.9 170.8 900.3 2823.3 4217.6 587.8 3094.8 788.7 389.6 708.3 875.9 557.1 802.7 583.0 1275.3 2976.3 2707.6 517.4 833.6 595.8 463.5 3258.4 3096.2 575.8 944.1 320.0 670.1 165.9 2939.3 773.9 416.9 46.9 2008.0 441.5 749.0 497.1 800.3 367.6 3028.1 723.7 979.9 761.3 3302.7 418.9 658.8 517.4 208.1 703.0 618.4 2883.1 155.2 328.2 75.4 175.8 1733.4 1179.8 145.3 261.4 350.7 170.3 137.7 625.1 219.7 0.8 241.0 345.2 221.3 496.2 69.6 499.9 51.9 0.9 253.5 157.6 61.1 1082.9 621.2 7.5 251.0 919.0 415.9 226.6 241.5 352.5 268.5 18.5 147.6 4.0 239.5 234.4 1.5 162.2 103.5 461.9 752.2 5.7 96.4 215.2 708.0 328.3 84.7 98.2 191.1 54.6 343.3 107.7 156.5 548.2 702.0 163.4 119.0 231.6 97.7 157.1 6.2 1.8 138.0 339.5 184.0 48.1 4967.5 33.2 66.9 6424.5 25.5 23.1 18.3 45.8 7959.0 13.6 16.9 31.1 809.3 191.4 4297.7 4427.4 13.6 4250.8 3041.2 3117.9 2823.3 4217.6 2976.3 2707.6 3258.4 3096.2 2939.3 3028.1 3302.7 2883.1 662.4 115.4 168.8 849.5 93.8 942.9 571.1 568.2 213.9 152.4 660.2 512.1 240.7 1361.2 514.5 641.9 29.2 476.8 603.3 1889.9 414.8 489.9 46.2 441.1 795.0 728.2 882.1 252.1 4.5 783.6 308.7 3026.2 981.7 631.0 359.9 687.0 491.9 2563.0 1816.7 48.8 11.2 1360.6 691.7 4301.1 18746.6 184.3 2132.6 4542.6 1563.5 87.1 2025.6 248.7 99.9 263.9 6.0 1458.5 2342.1 1790.4 67.9 786.0 4301.1 1098.6 364.4 36.3 2195.7 1417.0 846.2 125.5 400.6 461.5 822.0 469.0 117.4 208.1 1039.4 1079.7 CTNS "CTNS-LSB, PQLC4, SLC66A4" ENSG00000040531 "Cystinosin, lysosomal cystine transporter" O60931 17 3636459-3663103 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Melanin biosynthesis, Protein transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 35.5;Late spermatids: 29.3;Theca cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 34.3;granulocytes: 27.9;monocytes: 10.4" "Cell line enhanced" "Detected in all" "HDLM-2: 144.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046947 Supported "Vesicles,Intermediate filaments" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Intermediate filaments" "HPA046947: AB_2679872" "unprognostic (1.64e-1)" "unprognostic (1.70e-1)" "unprognostic (1.21e-1)" "unprognostic (8.25e-2)" "unprognostic (8.39e-2)" "prognostic favorable (7.33e-4)" "unprognostic (1.28e-2)" "unprognostic (8.02e-2)" "unprognostic (1.94e-1)" "unprognostic (6.62e-3)" "prognostic favorable (6.39e-5)" "unprognostic (8.40e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-1)" "unprognostic (5.64e-2)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" 10.3 19.5 9.5 10.0 17.0 10.2 9.6 13.5 12.1 20.3 12.1 8.3 12.2 11.3 6.4 8.7 10.3 13.1 10.5 10.8 10.3 15.2 15.9 11.6 10.0 16.5 16.8 12.1 27.0 13.6 9.6 12.9 18.0 10.8 7.2 6.8 12.0 11.6 15.3 19.2 11.0 8.6 10.9 12.1 15.0 24.8 13.2 8.8 9.2 7.4 9.5 9.1 9.4 28.0 17.6 37.0 22.6 18.2 34.5 16.9 13.0 19.6 28.8 21.1 26.0 21.0 16.0 10.2 17.8 11.6 55.9 40.1 19.8 12.1 12.6 144.3 33.7 10.8 32.2 19.3 46.5 8.0 81.3 23.8 14.2 20.2 15.4 28.1 22.2 18.7 12.6 15.9 16.6 15.1 7.8 7.9 9.8 12.2 16.8 16.4 9.3 23.0 15.3 16.2 3.9 17.2 19.2 24.4 20.3 19.0 17.1 7.7 24.2 17.2 11.6 40.3 13.3 12.4 20.0 4.2 28.1 7.8 11.8 27.9 10.4 21.8 3.0 6.9 4.9 5.8 4.0 5.7 9.7 4.9 4.5 5.5 3.1 5.2 7.1 34.3 4.3 7.3 9.5 17.0 13.5 12.1 10.8 10.3 16.5 16.8 18.0 10.9 13.2 28.0 4.4 3.2 2.2 6.5 4.8 1.7 3.5 2.5 4.0 1.6 6.3 5.0 5.2 5.7 2.7 12.9 10.4 6.1 5.2 3.6 0.0 6.7 35.5 5.7 4.4 5.3 2.4 4.0 3.4 6.4 7.1 6.0 7.7 4.3 8.2 6.7 9.3 7.6 25.2 5.0 3.4 2.5 4.1 7.2 5.9 29.3 9.6 12.1 5.4 3.7 10.0 6.5 3.1 5.5 11.1 6.4 3.3 12.8 4.5 6.5 3.2 9.5 7.0 3.9 6.6 3.7 3.5 19.7 8.7 2.9 2.4 8.5 3.3 30.9 1.8 3.2 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2744.5;Kupffer cells: 1774.9;Macrophages: 1224.3" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 390.6;classical monocyte: 610.1;intermediate monocyte: 467.3;myeloid DC: 287.4;non-classical monocyte: 307.6;plasmacytoid DC: 410.1" "Group enriched" "Detected in all" 6 "dendritic cells: 410.1;granulocytes: 390.6;monocytes: 610.1" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1607.5;fHDF/TERT166: 1436.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 100000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" 443.9 304.5 65.6 399.7 71.2 87.0 249.0 65.9 77.2 583.2 101.0 312.4 120.8 379.2 116.9 421.6 368.4 230.6 447.0 64.7 95.5 420.6 497.2 428.9 289.6 100.4 90.8 169.1 135.4 79.6 156.8 253.2 107.4 255.5 159.3 33.6 437.3 156.6 237.4 184.7 260.2 316.1 91.9 521.1 194.3 33.2 204.5 60.9 1150.7 99.3 104.0 431.9 477.8 159.2 66.6 283.4 4.0 94.9 657.3 754.5 128.3 885.0 1607.5 258.4 299.5 10.3 294.4 1.5 32.2 1436.1 419.3 279.5 65.3 157.1 195.6 25.9 52.6 58.8 10.0 397.1 479.2 7.7 73.7 296.4 532.2 327.2 427.3 611.5 33.4 20.2 81.7 260.7 194.6 62.5 6.5 23.1 16.3 839.7 91.3 33.6 39.3 202.7 2.6 121.1 4.9 68.6 165.1 68.6 514.6 110.1 97.8 68.7 922.4 766.5 111.9 129.9 259.3 182.7 178.5 4.8 432.5 22.9 249.4 390.6 610.1 90.6 26.3 467.3 35.4 44.1 79.0 31.5 287.4 38.8 48.3 21.5 97.8 31.3 307.6 410.1 78.7 703.7 65.6 71.2 65.9 77.2 64.7 95.5 100.4 90.8 107.4 91.9 204.5 159.2 87.7 109.0 171.4 17.6 54.8 54.7 441.6 563.2 54.7 55.2 94.1 74.5 320.1 165.8 331.7 114.0 41.7 279.4 122.4 147.9 27.4 294.6 15.6 105.8 240.1 163.0 154.7 210.2 36.2 238.2 341.7 155.0 44.4 183.5 179.4 105.9 204.2 239.5 2744.5 58.9 42.8 94.2 158.7 1774.9 436.5 18.5 76.4 1224.3 161.9 70.3 373.1 117.4 24.7 19.1 12.9 363.9 154.0 92.9 47.3 295.5 198.6 351.8 180.8 40.0 39.5 39.4 149.9 10.8 21.0 160.3 40.5 649.6 56.0 32.1 139.6 321.4 CTSC "DPP1, PALS, PLS" ENSG00000109861 "Cathepsin C" P53634 11 88265069-88359684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 900.7;Club cells: 471.8;Hofbauer cells: 1100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1078.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025364, HPA066610, HPA068434" Enhanced Supported Vesicles "Intracellular and membrane" No No 19000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB025364: , HPA066610: AB_2685694, HPA068434: AB_2685989" "unprognostic (4.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (1.10e-1)" "unprognostic (3.70e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (9.30e-5)" "unprognostic (1.62e-1)" "unprognostic (1.04e-1)" "unprognostic (1.56e-2)" "unprognostic (3.11e-2)" "unprognostic (3.35e-1)" "prognostic favorable (4.80e-4)" "unprognostic (2.93e-1)" "unprognostic (4.35e-2)" "unprognostic (8.10e-2)" "unprognostic (4.07e-2)" 173.2 60.7 9.9 185.1 9.6 71.7 63.4 11.1 24.9 77.9 14.2 143.1 121.0 43.9 28.5 63.3 54.0 182.0 38.5 9.5 10.1 234.7 82.0 272.6 243.7 14.0 11.9 22.1 52.2 42.4 39.3 253.3 13.3 26.0 191.5 3.7 131.6 28.9 18.8 29.6 128.8 88.9 11.5 197.2 73.6 22.8 19.5 63.7 43.6 31.9 140.6 176.3 43.3 21.3 80.3 75.9 27.6 69.9 103.7 286.1 218.4 626.5 1078.4 372.8 270.3 194.7 361.3 117.3 278.9 365.2 84.3 133.6 50.4 269.2 341.9 204.7 82.8 144.5 188.0 233.5 140.2 188.9 108.7 419.1 198.8 284.5 697.4 302.1 377.6 122.3 155.3 145.4 54.8 14.8 89.1 295.1 172.2 551.5 244.9 113.6 30.7 227.0 451.3 106.6 8.8 66.8 81.2 114.9 80.6 185.4 27.9 152.7 149.3 23.5 190.5 156.8 364.6 61.9 81.0 122.9 56.8 435.8 122.4 85.5 203.8 309.7 230.1 415.6 194.9 47.2 99.6 198.2 209.9 26.3 49.5 115.3 215.0 200.5 582.9 425.0 162.7 243.3 9.9 9.6 11.1 24.9 9.5 10.1 14.0 11.9 13.3 11.5 19.5 21.3 78.6 22.4 88.1 0.3 40.8 30.1 7.3 900.7 33.6 1.5 15.9 14.6 4.4 52.9 471.8 40.5 0.0 414.1 330.6 37.9 29.4 29.8 1.6 13.4 135.6 94.8 11.4 29.7 3.0 90.6 159.2 114.4 39.8 21.2 75.3 25.5 26.4 15.8 1100.6 0.0 8.2 19.4 158.7 344.7 200.7 7.9 198.5 391.7 48.0 61.8 185.4 0.5 299.7 13.6 0.4 44.8 72.3 25.6 78.5 8.5 20.2 166.4 93.7 0.8 59.2 4.4 150.8 3.0 11.1 43.3 27.1 227.3 170.6 286.7 44.9 16.1 CTSF "CATSF, CLN13" ENSG00000174080 "Cathepsin F" Q9UBX1 11 66563464-66568879 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 320.9;Muller glia cells: 196.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SiHa: 23.1;SK-MEL-30: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002141, HPA031431" Approved Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 5800000 "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum, Plasma membrane" "CAB002141: AB_563471, HPA031431: " "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (7.22e-3)" "unprognostic (2.25e-2)" "unprognostic (6.72e-2)" "unprognostic (2.67e-2)" "unprognostic (2.76e-2)" "unprognostic (3.69e-1)" "unprognostic (4.14e-1)" "unprognostic (1.69e-2)" "unprognostic (9.12e-2)" "prognostic favorable (8.92e-7)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (2.42e-1)" 57.8 70.0 68.1 0.8 76.3 0.3 62.2 74.5 74.0 78.8 90.2 76.7 3.0 89.2 21.9 15.6 70.8 10.0 100.2 63.2 74.2 46.9 66.0 32.9 3.6 75.0 70.3 99.1 31.7 20.0 43.3 3.8 68.4 53.5 3.5 26.2 55.7 17.1 91.9 44.4 29.5 12.2 77.2 25.0 54.3 109.7 71.0 3.0 40.6 27.6 3.0 56.6 58.7 86.6 0.0 17.0 3.1 5.4 14.2 8.6 3.4 13.0 11.4 6.3 2.3 0.0 2.2 0.0 21.3 10.4 0.0 1.2 6.8 2.6 4.8 3.7 0.0 0.5 7.0 0.0 9.9 0.3 4.4 22.3 9.1 0.8 1.6 13.7 3.8 2.0 5.4 1.6 5.2 4.6 0.1 1.7 0.9 3.7 9.7 0.0 0.0 1.5 7.1 0.3 4.3 6.9 23.1 0.3 59.5 0.3 7.4 0.6 3.3 1.8 2.9 1.5 1.2 21.2 0.2 0.0 2.2 0.0 2.9 0.0 0.4 0.3 3.9 0.6 4.1 1.5 3.5 4.6 0.6 1.4 6.4 4.1 0.1 4.6 0.2 0.9 1.3 2.2 68.1 76.3 74.5 74.0 63.2 74.2 75.0 70.3 68.4 77.2 71.0 86.6 36.6 12.8 15.6 31.3 5.9 39.8 62.4 8.5 37.5 107.9 45.3 80.6 57.9 41.5 7.4 36.8 41.7 31.6 9.6 0.6 15.6 13.1 163.3 1.7 22.8 27.2 12.0 11.4 26.5 7.5 9.5 118.1 8.2 5.3 9.5 52.1 56.0 67.8 14.9 134.6 31.3 3.1 18.3 21.5 32.8 320.9 145.7 13.1 156.5 12.2 3.1 196.6 17.5 21.6 29.4 5.9 3.2 121.9 12.9 50.5 1.3 44.7 3.3 77.9 78.9 62.0 45.9 169.6 43.3 3.6 25.3 23.7 9.5 30.7 4.3 32.9 CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 349.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1569.9;Proximal tubular cells: 523.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 208.5;intermediate monocyte: 137.7;memory B-cell: 83.3;myeloid DC: 183.6;naive B-cell: 56.0;non-classical monocyte: 94.8" "Group enriched" "Detected in all" 5 "B-cells: 83.3;dendritic cells: 183.6;monocytes: 208.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 306.4;HaCaT: 228.2;HDLM-2: 183.0;OE19: 197.4;RT4: 362.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" NA NA 8700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favorable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" 34.3 36.4 29.4 100.6 30.2 36.9 48.8 29.9 47.1 112.8 31.4 32.5 77.8 46.7 26.8 37.9 57.6 104.6 51.3 29.6 32.9 238.2 89.5 349.6 191.8 30.8 31.4 30.0 75.5 77.6 10.1 25.7 31.5 59.7 27.3 4.7 63.0 70.7 16.3 48.4 56.7 43.1 30.7 51.8 93.9 10.1 32.7 51.8 27.7 37.7 131.3 202.2 30.6 32.4 122.0 10.0 1.2 30.5 5.4 0.5 20.3 8.6 3.0 13.9 7.0 17.6 306.4 34.6 12.6 0.0 13.5 228.2 5.2 52.6 10.1 183.0 0.4 3.0 1.3 38.4 12.1 0.4 7.1 5.6 10.7 0.2 0.0 59.4 1.0 5.9 76.0 0.0 17.9 2.8 32.6 87.8 8.9 197.4 4.9 0.3 0.4 5.9 49.9 362.1 2.6 5.2 41.5 27.8 75.4 10.1 12.5 48.0 16.4 0.2 6.2 0.0 5.3 0.8 92.4 19.5 0.1 89.2 12.3 0.0 208.5 2.0 7.6 137.7 29.7 83.3 20.5 7.4 183.6 56.0 1.8 3.8 8.7 3.2 94.8 22.9 18.3 147.5 29.4 30.2 29.9 47.1 29.6 32.9 30.8 31.4 31.5 30.7 32.7 32.4 169.8 237.2 1569.9 59.1 127.4 24.2 280.7 363.9 30.1 1.3 45.5 41.7 26.2 358.9 258.7 367.8 4.2 19.8 8.1 9.1 84.1 225.0 25.3 67.0 86.0 124.5 9.1 3.0 2.2 142.0 39.6 53.8 106.0 42.8 32.8 2.7 14.3 115.5 256.7 0.0 2.9 18.6 101.7 177.8 259.6 22.6 73.0 350.4 80.0 15.9 360.9 22.6 5.2 1.5 1.1 84.6 16.0 6.0 155.8 112.0 153.0 523.2 261.6 6.6 19.7 4.5 22.3 12.3 56.4 41.6 18.6 23.4 29.4 17.8 40.1 340.4 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87724051-87731469 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 563.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1081.6;Extravillous trophoblasts: 1012.3;Hepatic stellate cells: 580.4;Hofbauer cells: 1105.7;Macrophages: 537.2;Syncytiotrophoblasts: 1543.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 128.1;non-classical monocyte: 195.2" "Lineage enriched" "Detected in many" 12 "monocytes: 195.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 2305.0;HSkMC: 1061.0" "Low region specificity" "Detected in all" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 17000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000459: AB_2292484, HPA070413: " "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.19e-3)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.15e-5)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (6.80e-2)" "unprognostic (3.21e-1)" "prognostic favorable (4.34e-4)" "unprognostic (5.64e-3)" "unprognostic (2.26e-2)" "unprognostic (1.72e-1)" "unprognostic (7.11e-3)" 232.4 86.6 49.2 136.0 55.4 84.8 110.0 52.9 67.5 69.5 67.9 110.3 39.7 108.1 81.6 33.3 108.4 85.0 112.5 47.0 52.3 207.3 333.5 154.9 101.1 54.4 54.0 96.4 61.9 151.1 69.5 563.6 57.5 68.2 58.8 32.3 77.6 91.7 71.9 39.8 57.1 125.2 52.4 124.4 71.4 80.1 112.2 33.0 76.1 79.8 49.4 209.8 48.0 59.6 88.1 423.0 32.6 55.3 514.0 2305.0 198.4 267.2 781.8 232.2 300.6 43.0 86.3 0.0 128.9 355.4 754.0 67.5 49.8 86.0 198.4 1.9 37.8 18.1 111.2 105.1 352.6 0.1 51.4 1061.0 138.9 373.7 134.9 186.6 194.9 0.0 162.5 0.7 326.6 115.6 0.5 9.9 67.7 128.6 77.5 21.6 21.5 0.6 158.6 39.0 42.8 50.6 62.1 133.5 312.3 177.9 14.5 97.9 296.9 190.8 104.7 750.6 125.9 18.5 84.1 0.9 692.6 0.2 67.9 0.3 13.5 0.6 0.3 128.1 0.0 0.0 6.6 0.1 7.9 0.1 16.7 1.3 0.5 0.2 195.2 0.3 1.7 10.1 49.2 55.4 52.9 67.5 47.0 52.3 54.4 54.0 57.5 52.4 112.2 59.6 86.1 41.7 52.9 15.3 11.2 37.7 82.1 58.0 15.4 43.8 12.2 33.4 96.8 87.2 46.4 75.4 18.8 1081.6 0.3 16.3 27.4 91.8 5.3 48.1 119.9 110.0 11.5 251.2 18.6 93.4 1012.3 261.7 10.2 27.6 29.7 63.6 580.4 122.6 1105.7 13.5 24.0 8.5 20.3 206.9 105.4 17.4 156.9 537.2 64.0 14.0 16.2 79.5 0.0 17.6 31.7 67.2 5.6 187.3 1.9 34.5 8.0 138.3 67.3 45.4 92.1 176.9 136.3 207.4 60.5 6.8 34.0 1543.6 10.8 30.8 11.7 44.8 CTSZ CTSX ENSG00000101160 "Cathepsin Z" Q9UBR2 20 58985686-59008238 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1078.9;Langerhans cells: 983.5;Macrophages: 652.3;monocytes: 723.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 542.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025114, HPA049876, HPA053504" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "CAB025114: , HPA049876: AB_2680927, HPA053504: AB_2682172" "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.07e-2)" "unprognostic (1.11e-3)" "unprognostic (8.25e-3)" "unprognostic (1.15e-1)" "unprognostic (4.12e-2)" "unprognostic (6.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (1.96e-1)" "unprognostic (6.92e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" 178.1 117.8 18.9 208.8 21.8 99.8 137.0 20.5 32.0 92.1 59.6 173.8 215.4 87.3 13.4 53.1 88.9 89.4 152.6 15.3 33.9 125.6 356.4 233.3 271.5 31.6 23.5 71.0 89.4 91.8 112.5 118.7 27.9 87.8 77.1 4.1 181.0 66.3 58.7 58.5 226.0 97.9 26.2 234.4 88.2 24.6 47.2 57.1 122.3 54.6 91.3 146.3 69.0 45.4 205.4 139.8 1.1 1.1 114.2 124.2 106.5 291.0 225.4 187.4 152.3 231.6 324.6 96.5 213.9 542.1 0.5 160.1 51.4 257.5 30.2 362.1 13.6 80.3 169.0 0.8 137.3 9.0 331.0 130.9 127.8 83.1 62.4 34.8 281.3 1.1 74.0 48.7 90.0 1.1 1.3 70.6 11.5 43.5 158.2 2.9 0.4 135.7 86.3 25.5 2.7 1.7 222.4 258.4 0.8 19.5 131.9 148.4 420.5 1.4 161.8 209.0 2.0 253.7 172.0 18.2 2.8 207.9 0.4 1.2 1.5 1.6 0.6 1.4 0.4 1.1 0.6 0.4 1.1 1.4 0.7 0.8 1.6 0.5 2.9 1.8 0.3 0.7 18.9 21.8 20.5 32.0 15.3 33.9 31.6 23.5 27.9 26.2 47.2 45.4 132.1 16.0 5.3 5.9 119.8 50.3 64.5 33.8 24.5 6.7 67.4 99.6 21.7 62.9 14.1 71.7 0.0 38.2 104.8 303.6 23.5 176.0 3.5 52.9 47.7 82.2 27.1 63.3 5.3 42.4 104.8 71.5 19.4 71.3 10.8 68.4 62.8 363.0 1078.9 11.8 3.0 56.6 26.4 334.0 983.5 6.0 13.1 652.3 101.4 23.4 723.6 58.6 21.6 2.5 2.5 82.6 217.5 13.9 96.3 50.6 339.8 90.0 18.8 5.0 46.0 67.5 74.5 3.7 4.8 14.5 41.5 41.3 33.4 3.3 99.7 52.7 CYP4B1 ENSG00000142973 "Cytochrome P450 family 4 subfamily B member 1" P13584 1 46757838-46819413 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 242.2" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 1227.5;Club cells: 405.1;Respiratory ciliated cells: 763.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 56.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "RT4: 286.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA004331 Approved Supported Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA004331: AB_1078616" "unprognostic (2.29e-2)" "prognostic favorable (5.99e-4)" "unprognostic (7.01e-2)" "unprognostic (1.11e-1)" "unprognostic (2.28e-1)" "unprognostic (8.31e-2)" "unprognostic (1.16e-2)" "unprognostic (1.98e-2)" "unprognostic (2.65e-1)" "unprognostic (2.59e-1)" "unprognostic (6.12e-2)" "unprognostic (5.46e-2)" "unprognostic (7.33e-2)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.22e-3)" "unprognostic (6.69e-3)" 81.8 4.9 0.3 0.0 0.3 0.0 62.0 0.2 0.6 13.4 1.2 14.6 1.3 9.5 1.7 44.0 48.0 0.5 40.2 0.2 0.3 2.4 0.1 242.2 0.5 0.3 0.3 1.7 3.4 0.7 9.3 1.2 0.3 22.7 0.7 0.0 16.6 15.8 24.0 42.7 15.2 0.1 0.3 0.4 11.5 0.5 0.4 3.1 22.3 24.6 15.2 81.7 30.5 0.3 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 35.6 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 286.7 0.1 0.0 0.0 11.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.6 0.2 0.3 0.3 0.3 0.3 0.3 0.4 0.3 60.8 1227.5 89.3 0.0 0.0 0.5 139.6 111.5 36.5 0.0 2.0 1.5 6.4 1.5 405.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.7 93.8 12.5 23.5 0.0 0.0 0.1 0.0 0.2 47.9 1.1 8.5 6.3 0.0 1.4 0.0 0.6 0.0 0.1 0.0 48.8 0.0 0.3 0.9 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 6.9 0.0 1.1 763.9 0.0 0.0 3.0 23.3 0.1 0.1 71.4 4.1 0.8 1.8 0.0 0.0 163.0 DAG1 "156DAG, A3a, AGRNR, DAG" ENSG00000173402 "Dystroglycan 1" Q14118 3 49468703-49535618 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 207.9;Skeletal myocytes: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 280.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001960, CAB016353, HPA070563" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 84000000 "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Plasma membrane" Nucleoplasm "CAB001960: , CAB016353: AB_627292, HPA070563: " "unprognostic (1.58e-1)" "unprognostic (5.14e-1)" "unprognostic (6.71e-3)" "unprognostic (3.32e-1)" "unprognostic (7.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.67e-1)" "unprognostic (3.27e-2)" "unprognostic (8.18e-2)" "unprognostic (3.91e-2)" "unprognostic (5.70e-3)" "unprognostic (1.10e-1)" "prognostic favorable (2.59e-4)" "unprognostic (9.22e-2)" "unprognostic (1.99e-2)" "unprognostic (7.43e-2)" "unprognostic (1.57e-2)" 25.2 22.0 31.5 17.9 32.6 5.4 26.6 30.7 30.7 26.2 25.5 38.8 24.0 32.1 16.2 28.3 31.8 26.4 68.9 30.1 28.9 28.1 43.0 31.8 9.4 33.3 31.4 24.6 51.4 44.3 18.6 77.0 28.6 29.5 30.6 9.8 31.8 37.9 93.8 28.5 24.0 45.9 30.2 12.6 32.0 26.9 34.1 10.5 25.5 95.7 14.3 27.8 22.0 31.2 92.3 92.4 61.9 152.3 80.3 38.8 280.9 63.9 93.7 108.0 69.0 74.2 96.0 13.0 62.2 103.2 87.6 168.4 55.6 81.2 67.2 12.7 18.6 9.6 84.3 87.2 35.5 11.2 17.4 33.3 72.5 100.3 33.3 96.7 97.1 15.3 14.5 9.8 31.2 75.5 10.1 8.1 66.4 110.0 31.2 5.5 60.5 22.3 82.5 126.4 21.8 45.2 74.8 206.0 105.5 170.3 171.6 22.8 51.8 39.1 63.9 76.0 91.4 11.0 24.2 8.1 50.4 12.6 245.9 2.3 1.2 0.7 1.1 1.3 1.2 1.2 0.9 0.9 0.7 1.0 1.0 1.0 2.2 1.1 2.5 1.3 0.7 1.4 31.5 32.6 30.7 30.7 30.1 28.9 33.3 31.4 28.6 30.2 34.1 31.2 19.0 54.5 18.4 32.0 4.0 14.3 8.0 31.7 17.1 7.4 36.1 46.4 56.6 30.0 20.6 35.0 4.2 116.4 5.8 37.3 1.9 32.4 30.0 30.2 17.3 20.9 33.0 14.3 15.6 79.6 118.4 26.1 37.8 37.9 7.0 207.9 16.8 59.9 21.2 3.3 16.5 29.7 14.2 8.6 7.0 20.0 21.5 6.3 33.8 9.4 5.6 27.1 5.2 19.6 10.7 57.2 21.4 36.9 5.1 14.4 18.9 7.6 23.2 8.7 46.0 326.1 36.2 7.1 19.9 19.0 17.0 95.9 5.9 10.0 29.2 10.2 DAPK2 "DRP-1, MGC119312" ENSG00000035664 "Death associated protein kinase 2" Q9UIK4 15 63907036-64072033 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 50.2;thyroid gland: 41.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 86.6;Late spermatids: 112.5;Oligodendrocytes: 99.9;Proximal enterocytes: 64.0" "Cancer enriched" "Detected in many" 15 "thyroid cancer: 30.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "basophil: 94.3;eosinophil: 213.0;neutrophil: 65.9" "Lineage enriched" "Detected in many" 25 "granulocytes: 213.0" "Cell line enhanced" "Detected in many" "ASC diff: 10.6;HaCaT: 9.2;HMC-1: 18.3;MCF7: 9.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071581 Supported "Golgi apparatus,Vesicles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA071581: AB_2686421" "unprognostic (3.20e-2)" "unprognostic (4.07e-2)" "unprognostic (4.23e-2)" "unprognostic (1.95e-3)" "unprognostic (2.88e-2)" "unprognostic (1.30e-2)" "unprognostic (2.32e-1)" "prognostic favorable (5.63e-4)" "unprognostic (1.04e-1)" "unprognostic (3.18e-1)" "unprognostic (9.21e-2)" "unprognostic (8.51e-2)" "unprognostic (4.77e-7)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (3.20e-3)" "unprognostic (9.07e-2)" 12.5 2.2 5.9 2.7 7.6 15.9 8.8 5.9 8.1 6.7 4.3 9.8 20.6 1.6 0.2 3.3 1.7 1.5 28.0 5.5 6.7 4.5 2.0 20.0 3.1 6.2 6.8 0.9 2.7 0.9 1.6 0.4 6.6 5.1 6.6 0.4 7.5 3.6 50.2 8.1 21.3 1.7 6.0 7.8 9.9 3.1 6.6 1.5 41.9 19.6 2.6 2.4 9.5 9.5 3.1 2.3 6.1 1.5 10.6 0.5 0.0 2.1 6.7 1.1 1.2 1.0 1.6 0.2 0.7 6.7 3.7 9.2 3.8 0.1 0.6 0.2 0.2 1.3 4.5 0.1 0.1 0.1 18.3 1.1 7.9 0.4 0.2 7.0 0.7 0.1 0.4 0.1 0.7 9.7 0.0 0.4 0.7 3.1 2.2 2.9 0.0 0.3 0.0 3.2 0.4 0.3 0.4 1.2 0.0 1.5 5.2 0.4 0.4 0.9 1.0 1.4 1.8 0.6 0.2 0.0 0.0 3.0 0.3 94.3 0.2 213.0 2.1 0.1 0.9 1.3 0.6 2.2 0.2 0.4 0.0 1.4 65.9 2.7 0.1 8.6 0.1 1.3 5.9 7.6 5.9 8.1 5.5 6.7 6.2 6.8 6.6 6.0 6.6 9.5 24.9 86.6 22.3 5.2 4.8 11.6 7.0 8.7 0.6 0.1 9.4 7.4 46.2 1.5 14.6 0.0 0.0 0.1 22.6 45.2 1.9 9.1 25.3 3.0 1.6 6.4 8.4 0.8 15.9 35.6 0.2 8.7 16.3 7.8 15.2 1.3 5.7 1.3 0.4 5.0 2.1 17.0 6.1 1.3 0.8 112.5 3.1 3.2 0.0 15.0 0.3 2.1 2.1 11.1 99.9 9.4 30.6 5.7 0.4 12.0 64.0 0.3 2.8 0.3 13.1 7.6 4.5 2.6 4.9 0.5 4.1 0.1 14.9 1.9 19.6 14.0 DBNL "ABP1, HIP-55, SH3P7" ENSG00000136279 "Drebrin like" Q9UJU6 7 44044640-44069456 "Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Endocytosis, Immunity, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 338.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020265, HPA027735" Enhanced Supported "Vesicles,Plasma membrane" NA NA 3500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Vesicles, Plasma membrane" "HPA020265: AB_1850723, HPA027735: AB_10603790" "unprognostic (9.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.04e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.12e-5)" "unprognostic (2.25e-1)" "unprognostic (6.18e-3)" "unprognostic (1.83e-1)" "unprognostic (5.88e-2)" "unprognostic (8.92e-2)" "unprognostic (5.76e-3)" "unprognostic (5.92e-2)" "unprognostic (2.11e-1)" "unprognostic (1.79e-1)" "unprognostic (2.10e-1)" "unprognostic (1.46e-1)" "unprognostic (9.51e-2)" 58.1 51.6 44.2 62.8 45.1 76.6 51.3 41.7 50.4 72.4 39.9 54.6 34.7 56.0 20.2 189.0 47.8 47.2 49.2 45.8 45.2 50.7 51.1 57.8 99.6 46.2 44.8 38.0 44.3 38.4 47.8 34.9 48.4 57.0 30.6 9.4 57.5 38.0 34.3 59.9 64.7 44.8 44.3 119.5 54.7 20.8 44.6 64.8 47.6 16.4 89.1 60.3 92.0 43.4 57.6 89.1 60.5 56.6 77.0 49.7 46.0 95.9 93.6 111.5 91.5 90.0 82.5 132.3 70.0 126.1 133.6 101.9 35.6 130.6 40.7 70.6 38.9 51.9 73.8 52.4 78.5 75.8 70.3 46.6 53.3 107.1 35.2 71.5 74.1 83.9 63.8 49.3 105.5 91.5 136.5 85.3 43.1 72.9 73.0 69.4 48.1 64.5 69.8 90.5 65.6 89.8 69.6 121.5 24.4 43.8 94.0 99.4 121.1 82.7 75.5 49.5 113.6 102.7 49.4 81.2 78.3 83.2 183.8 263.3 377.1 295.0 190.3 422.7 148.3 253.9 138.0 155.0 362.5 261.7 136.5 145.1 357.4 192.4 437.9 376.6 183.1 558.8 44.2 45.1 41.7 50.4 45.8 45.2 46.2 44.8 48.4 44.3 44.6 43.4 49.9 44.8 36.2 10.7 105.4 17.6 34.1 62.9 19.4 33.0 26.7 24.0 30.6 25.8 42.2 31.3 35.5 78.9 101.6 58.5 45.0 87.0 10.3 30.7 39.3 44.8 37.8 45.8 7.4 73.2 146.4 39.3 54.6 50.7 65.9 42.3 32.5 22.5 176.0 40.4 6.7 50.0 38.7 129.6 48.6 10.6 37.0 113.4 55.2 7.5 338.3 42.5 112.3 5.5 11.4 105.9 74.0 33.8 50.2 31.5 49.0 33.6 21.6 38.6 6.6 29.0 54.6 24.4 12.8 64.4 26.7 87.3 69.5 51.9 44.0 51.1 DCT TYRP2 ENSG00000080166 "Dopachrome tautomerase" P40126 13 94436811-94479682 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "skin 1: 107.4" "Cell type enriched" "Detected in some" 23 "Melanocytes: 3552.1" "Cancer enriched" "Detected in some" 215 "melanoma: 155.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 272 "SK-MEL-30: 257.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA010742, HPA010743, HPA010800, CAB017634" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Vesicles "CAB017634: AB_1130818, HPA010742: , HPA010743: AB_1847519, HPA010800: AB_1847520" "unprognostic (5.99e-2)" "unprognostic (1.67e-2)" "unprognostic (1.54e-2)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" "unprognostic (3.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.81e-2)" "unprognostic (6.07e-2)" "unprognostic (1.81e-1)" "unprognostic (3.64e-3)" "unprognostic (1.06e-2)" "unprognostic (6.18e-5)" "unprognostic (6.97e-2)" "unprognostic (9.87e-2)" "unprognostic (1.22e-3)" "unprognostic (2.42e-1)" 0.4 0.4 0.6 0.0 1.0 0.1 3.0 0.4 0.7 0.2 0.2 0.3 0.0 0.3 0.9 0.0 0.9 0.1 0.1 0.6 0.6 0.2 0.2 0.1 0.0 0.6 0.6 0.4 0.4 0.0 1.6 0.0 0.5 0.3 0.0 0.9 1.5 0.3 0.4 107.4 0.1 0.1 0.6 0.1 0.1 0.6 0.6 0.5 0.2 0.1 0.0 0.2 0.3 0.5 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 257.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.2 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.4 0.7 0.6 0.6 0.6 0.6 0.5 0.6 0.6 0.5 0.0 0.0 0.0 23.5 0.0 152.3 0.1 0.0 0.0 1.0 0.3 0.5 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.5 0.1 1.2 0.0 0.0 16.1 0.2 0.0 1.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 25.5 23.8 0.9 0.0 3552.1 1.9 0.0 3.5 0.0 6.6 2.4 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.5 1.0 0.5 0.8 0.0 33.4 0.0 0.9 0.1 0.0 0.0 DCUN1D4 KIAA0276 ENSG00000109184 "Defective in cullin neddylation 1 domain containing 4" Q92564 4 51843000-51916837 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 111.9;Oligodendrocytes: 131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036483, HPA036484" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles Nucleoplasm "HPA036483: AB_10670719, HPA036484: AB_10671843" "unprognostic (3.16e-2)" "unprognostic (2.65e-1)" "unprognostic (2.77e-3)" "unprognostic (1.41e-1)" "unprognostic (5.61e-2)" "unprognostic (1.61e-1)" "unprognostic (2.80e-2)" "unprognostic (1.37e-1)" "unprognostic (8.47e-3)" "unprognostic (1.61e-3)" "unprognostic (3.88e-3)" "unprognostic (1.83e-2)" "unprognostic (2.93e-3)" "unprognostic (2.14e-1)" "unprognostic (5.25e-2)" "unprognostic (1.10e-3)" "unprognostic (1.40e-1)" 14.0 17.8 14.5 7.3 14.1 2.8 9.8 14.4 20.3 13.3 8.1 15.0 5.9 13.6 11.5 10.4 12.7 11.4 12.1 13.4 17.3 14.9 28.9 9.1 7.5 16.0 16.2 16.0 9.1 9.5 15.7 6.9 17.2 12.0 8.5 15.7 13.4 16.9 11.8 7.7 9.7 17.3 14.2 9.4 13.3 17.0 18.9 6.5 13.2 11.4 6.1 16.9 10.9 16.4 10.6 18.9 25.5 36.7 25.6 27.5 9.8 31.1 23.2 18.0 15.9 11.8 12.1 8.1 20.1 35.2 23.5 11.2 31.0 19.8 27.8 4.9 9.5 13.8 14.9 28.7 54.9 20.4 17.9 25.1 23.7 19.6 17.9 27.0 19.2 7.4 15.6 5.9 35.3 15.2 24.1 13.6 14.5 21.1 15.1 11.4 12.2 4.4 23.1 12.4 14.4 15.6 13.1 17.8 28.9 13.9 18.4 12.3 28.8 24.0 19.7 19.7 25.7 11.1 18.1 7.3 16.6 18.8 14.4 6.8 3.6 8.8 5.7 3.3 8.5 3.6 6.4 6.5 2.5 2.4 6.0 6.8 1.4 3.7 2.4 1.5 3.2 4.4 14.5 14.1 14.4 20.3 13.4 17.3 16.0 16.2 17.2 14.2 18.9 16.4 13.1 6.4 14.1 86.2 9.7 37.2 19.2 16.5 16.5 23.3 18.1 11.7 40.6 14.3 13.2 16.5 16.7 5.0 9.8 14.9 13.7 10.6 76.3 10.7 16.1 17.9 6.7 11.8 90.9 12.2 8.5 23.1 21.9 10.0 13.3 18.9 17.2 35.8 8.2 30.3 88.6 7.2 12.2 7.3 18.4 111.9 14.9 7.2 32.0 51.5 5.3 14.9 15.5 69.4 131.4 13.3 10.9 25.9 6.3 17.2 8.9 24.1 18.1 17.8 0.0 13.4 20.8 24.6 25.5 17.3 33.2 3.4 11.1 12.4 8.9 15.0 DENND1A "FAM31A, FLJ21129, KIAA1608" ENSG00000119522 "DENN domain containing 1A" Q8TEH3 9 123379654-123930152 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 258.9;Excitatory neurons: 188.2;Inhibitory neurons: 175.8;Late spermatids: 88.5;Microglial cells: 178.0;Oligodendrocyte precursor cells: 165.4;Oligodendrocytes: 145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 9 "dendritic cells: 12.1;granulocytes: 20.4;monocytes: 21.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020481 Approved Vesicles,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Vesicles, Cytosol" "HPA020481: AB_2092106" "unprognostic (1.35e-1)" "unprognostic (3.96e-2)" "unprognostic (2.00e-1)" "unprognostic (4.25e-2)" "unprognostic (1.62e-2)" "unprognostic (1.47e-1)" "unprognostic (1.34e-1)" "unprognostic (3.19e-3)" "unprognostic (2.14e-2)" "unprognostic (2.14e-2)" "unprognostic (2.48e-3)" "unprognostic (5.63e-2)" "prognostic favorable (4.11e-5)" "unprognostic (1.25e-1)" "unprognostic (1.51e-1)" "unprognostic (9.66e-2)" "unprognostic (4.31e-2)" 8.5 8.3 8.2 10.3 8.3 27.0 7.1 2.7 10.3 7.9 6.8 10.6 11.3 8.3 4.6 7.7 8.7 7.2 7.3 8.1 6.2 11.4 10.8 6.9 9.0 5.6 6.0 7.9 6.2 11.9 10.2 11.3 4.9 7.7 9.6 10.3 6.1 7.6 8.4 6.9 12.6 9.9 4.8 14.2 6.9 9.5 6.4 7.1 10.8 4.8 6.2 7.6 6.5 5.7 29.0 16.7 14.7 28.0 9.8 15.3 68.3 27.4 41.0 22.9 19.6 23.0 12.5 23.1 5.5 22.3 30.1 15.9 12.6 19.9 22.2 9.8 9.7 10.9 39.1 17.1 13.2 13.2 7.0 14.2 17.6 18.9 32.2 8.0 20.6 21.8 30.3 17.2 18.7 16.5 15.8 19.1 29.4 33.1 25.2 24.3 14.4 19.5 11.4 10.1 31.1 25.3 22.1 14.4 16.9 9.6 19.8 32.8 9.7 24.5 9.4 28.9 14.6 26.0 21.7 16.0 20.6 25.9 16.5 20.4 21.1 4.3 1.8 14.6 0.9 1.7 1.3 0.8 12.1 1.8 0.8 1.0 12.8 0.8 12.8 1.9 0.6 5.3 8.2 8.3 2.7 10.3 8.1 6.2 5.6 6.0 4.9 4.8 6.4 5.7 6.4 0.0 1.5 258.9 10.0 5.1 2.6 2.5 1.8 16.1 4.8 4.3 7.7 7.2 1.7 16.5 16.7 10.0 6.8 25.3 5.9 4.3 35.1 5.0 8.2 10.5 12.0 20.2 188.2 5.1 32.2 7.6 20.9 3.9 4.5 8.8 7.5 14.5 18.0 32.0 175.8 7.6 2.0 21.4 8.2 88.5 14.6 18.7 3.6 178.0 18.7 11.6 5.2 165.4 145.2 6.1 9.5 11.3 13.1 5.3 18.3 16.0 2.9 13.1 0.0 6.7 5.9 3.8 1.4 3.8 2.8 8.8 5.3 4.5 7.8 3.9 DENND4C "bA513M16.3, C9orf55, C9orf55B, FLJ20686, RAB10GEF" ENSG00000137145 "DENN domain containing 4C" Q5VZ89 9 19230435-19374281 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 120.9;Oligodendrocyte precursor cells: 107.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014917, HPA015096" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" "Golgi apparatus, Vesicles, Cytosol" "HPA014917: AB_2261659, HPA015096: AB_1845831" "unprognostic (4.57e-2)" "unprognostic (1.73e-2)" "unprognostic (6.81e-2)" "unprognostic (1.71e-1)" "unprognostic (1.87e-2)" "unprognostic (1.48e-1)" "unprognostic (2.43e-2)" "unprognostic (3.38e-1)" "unprognostic (1.14e-1)" "unprognostic (1.02e-1)" "unprognostic (3.20e-2)" "unprognostic (2.39e-1)" "prognostic favorable (3.51e-5)" "unprognostic (3.27e-1)" "unprognostic (1.31e-1)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" 21.7 11.9 5.9 9.2 7.0 10.6 21.7 14.1 6.3 17.2 8.0 17.4 25.1 17.2 14.3 14.5 16.4 13.8 14.5 5.3 5.6 13.9 15.2 18.0 11.8 5.9 5.7 21.4 12.9 19.0 8.7 19.6 5.7 16.1 19.8 11.8 15.1 13.4 10.6 29.6 22.4 14.6 5.8 12.7 19.8 11.2 7.2 17.7 17.3 12.4 11.2 16.6 16.0 6.6 17.7 17.5 11.7 15.3 26.6 28.5 21.4 10.0 14.9 10.2 13.7 8.4 11.6 7.5 8.3 13.6 11.8 9.4 13.7 9.4 12.0 47.2 7.8 34.4 18.5 10.4 13.4 8.3 18.8 11.7 18.7 9.0 15.5 21.6 20.2 9.9 9.4 8.5 13.1 7.4 13.8 18.8 9.0 24.7 8.5 12.6 6.6 10.9 29.2 34.1 10.9 8.5 8.4 20.1 7.4 11.0 12.1 11.3 18.5 8.9 5.2 10.0 10.5 5.8 14.9 4.0 7.7 7.6 5.2 8.3 1.6 1.9 5.4 0.8 7.0 1.7 4.6 5.5 3.1 2.3 4.3 5.0 0.9 6.4 0.9 3.2 3.8 2.4 5.9 7.0 14.1 6.3 5.3 5.6 5.9 5.7 5.7 5.8 7.2 6.6 28.6 9.6 11.5 85.8 21.3 51.2 16.7 18.0 65.4 20.9 16.0 11.0 12.4 14.3 21.6 16.5 60.5 29.4 22.6 26.6 1.9 9.8 7.7 12.7 15.5 22.9 19.8 9.7 78.6 12.5 13.5 24.0 47.4 20.4 27.1 24.8 51.0 11.5 19.0 23.5 87.2 22.6 24.4 23.9 22.0 5.2 18.6 32.2 21.4 120.9 8.5 13.6 27.8 107.1 69.1 12.1 20.9 20.3 14.1 19.4 26.4 4.9 21.6 16.3 0.0 19.5 16.2 3.3 6.8 30.9 49.3 16.1 28.2 12.0 23.3 23.2 DENND6A "AFI1A, FAM116A, FLJ34969" ENSG00000174839 "DENN domain containing 6A" Q8IWF6 3 57625454-57693077 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 66.9;Inhibitory neurons: 65.4;Oligodendrocytes: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 18.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 18.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062618, HPA069725, HPA071711" Approved Supported Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA062618: AB_2684809, HPA069725: AB_2686184, HPA071711: AB_2686435" "unprognostic (6.20e-2)" "unprognostic (3.86e-2)" "prognostic favorable (9.21e-4)" "unprognostic (1.76e-1)" "unprognostic (7.75e-2)" "unprognostic (3.17e-1)" "prognostic unfavorable (6.36e-4)" "unprognostic (7.16e-2)" "unprognostic (1.17e-2)" "unprognostic (2.28e-3)" "unprognostic (5.97e-3)" "unprognostic (1.12e-1)" "prognostic favorable (7.77e-6)" "unprognostic (3.06e-1)" "unprognostic (1.63e-1)" "unprognostic (3.61e-3)" "unprognostic (2.94e-1)" 11.6 7.3 3.4 8.8 4.6 12.6 12.9 12.9 7.1 11.8 3.8 10.7 7.1 12.7 9.9 11.4 10.3 8.3 8.0 3.0 5.5 8.9 7.7 10.5 12.6 4.2 4.8 20.9 5.3 11.4 6.6 11.8 5.3 9.9 9.2 10.0 8.4 11.7 7.1 8.6 9.2 11.3 4.7 12.9 9.7 8.0 4.7 11.8 14.0 9.8 10.5 10.7 10.5 8.4 16.8 13.5 18.0 11.0 9.4 10.6 10.2 8.6 11.0 10.5 8.2 8.7 18.4 19.9 3.6 8.9 9.2 8.8 14.4 18.2 8.9 5.1 12.9 15.7 15.1 6.7 9.0 12.1 8.9 11.3 13.0 7.2 18.7 10.6 15.2 21.1 10.8 21.1 7.6 7.3 26.2 14.9 10.2 10.6 9.3 10.9 10.7 14.8 12.8 28.1 6.1 22.0 17.1 13.9 12.5 7.7 9.1 14.7 16.7 12.7 6.8 13.6 22.8 15.7 22.2 20.7 14.8 19.9 18.9 18.7 1.0 1.4 2.4 1.1 2.9 0.8 2.3 2.4 1.3 1.2 3.4 2.6 1.5 1.9 1.4 1.0 1.3 1.0 3.4 4.6 12.9 7.1 3.0 5.5 4.2 4.8 5.3 4.7 4.7 8.4 28.8 19.2 8.2 31.3 14.5 12.9 11.8 10.6 12.0 16.2 9.9 9.1 20.8 11.5 10.0 5.5 8.4 6.4 21.4 5.7 3.9 8.1 22.2 10.1 25.6 16.0 3.0 16.2 66.9 10.9 4.4 15.7 10.2 17.1 2.5 24.1 20.7 11.1 11.1 10.1 65.4 5.5 12.2 34.3 9.9 11.3 11.8 16.8 3.6 47.8 16.8 10.2 20.6 42.3 74.3 18.9 3.5 14.3 9.5 8.4 6.5 8.9 8.0 14.5 6.6 19.2 18.3 13.3 5.0 14.1 10.7 2.3 19.6 16.7 6.1 13.0 DEPP1 "C10orf10, DEPP, FIG, Fseg" ENSG00000165507 "DEPP1 autophagy regulator" Q9NTK1 10 44970981-44978809 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 889.5;breast: 697.2" "Cell type enhanced" "Detected in many" "Adipocytes: 192.0;Ductal cells: 146.3;Exocrine glandular cells: 113.0;Glandular and luminal cells: 87.1;Syncytiotrophoblasts: 300.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 143.2;HDLM-2: 106.7;HHSteC: 258.2;HSkMC: 201.6;HUVEC TERT2: 165.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB013687, HPA037818, HPA037819" Uncertain Supported Vesicles,Mitochondria "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria Vesicles "CAB013687: , HPA037818: , HPA037819: AB_2675685" "unprognostic (3.99e-2)" "unprognostic (4.69e-2)" "unprognostic (5.57e-2)" "unprognostic (3.55e-1)" "unprognostic (1.88e-2)" "unprognostic (5.66e-3)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (4.25e-1)" "unprognostic (5.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.89e-2)" "prognostic unfavorable (2.29e-6)" "unprognostic (2.30e-3)" "unprognostic (2.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.74e-1)" 889.5 48.4 62.3 19.4 71.4 4.5 697.2 59.5 71.8 153.0 50.3 145.7 16.7 168.5 16.5 65.7 334.2 68.5 260.6 55.5 71.9 95.4 131.6 508.6 63.0 175.9 72.3 297.8 349.7 23.0 85.2 76.5 93.4 82.6 12.0 28.2 119.7 22.8 165.8 165.0 94.8 68.8 101.6 32.8 104.6 19.3 87.4 25.2 200.5 52.2 47.6 177.6 139.1 90.6 30.2 0.2 0.5 0.4 143.2 69.5 7.4 0.2 10.2 0.4 1.8 1.1 11.2 0.0 1.6 13.5 7.1 1.2 1.2 9.1 0.7 106.7 4.0 0.1 0.1 11.0 258.2 0.1 0.1 201.6 0.4 0.1 1.4 24.9 165.0 0.0 0.2 63.2 0.6 0.0 0.1 1.7 0.2 0.6 0.9 5.1 1.7 25.7 0.5 10.9 5.6 0.3 0.0 1.3 5.8 17.0 0.2 7.0 1.6 7.8 5.6 0.5 7.3 1.7 2.8 0.4 44.2 2.6 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.4 62.3 71.4 59.5 71.8 55.5 71.9 175.9 72.3 93.4 101.6 87.4 90.6 192.0 0.0 24.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 47.0 27.8 0.0 0.0 6.2 31.3 0.0 53.8 1.4 0.0 37.2 146.3 0.0 61.3 33.2 60.0 0.0 0.0 0.0 113.0 14.7 79.3 0.0 87.1 0.0 8.4 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 65.0 0.0 0.0 0.5 0.0 0.0 25.5 5.8 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 300.2 1.8 0.8 0.0 0.0 DIAPH2 "DIA, DIA2, POF, POF2" ENSG00000147202 "Diaphanous related formin 2" O60879 X 96684663-97604997 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Oogenesis" "Developmental protein" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 171.0;Late spermatids: 177.8;Microglial cells: 301.7;Oligodendrocyte precursor cells: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005647, CAB015461, CAB068183, CAB068184" Enhanced Supported "Nucleoli,Endoplasmic reticulum,Vesicles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 32: U-937 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum, Vesicles" Nucleoli "CAB015461: AB_831223, CAB068183: AB_2665693, CAB068184: AB_2665694, HPA005647: AB_1078657" "unprognostic (5.75e-2)" "unprognostic (4.13e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (2.16e-5)" "unprognostic (1.58e-1)" "unprognostic (6.48e-2)" "unprognostic (4.06e-1)" "unprognostic (1.07e-2)" "unprognostic (2.41e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (2.12e-4)" "unprognostic (3.39e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (6.44e-2)" "unprognostic (3.11e-2)" "unprognostic (6.99e-3)" "unprognostic (6.08e-3)" 10.7 3.3 3.7 6.4 6.4 17.7 7.0 0.0 4.3 10.6 17.3 8.6 4.3 5.5 3.5 7.7 6.7 5.7 5.4 6.4 3.1 3.1 12.3 8.2 3.8 0.6 0.9 7.7 4.9 7.0 2.0 12.5 1.0 6.1 8.7 3.0 6.6 7.6 12.0 5.3 5.3 7.4 0.2 3.8 7.4 9.4 1.5 6.0 3.9 9.1 3.9 7.4 9.8 1.8 0.0 6.5 3.1 6.3 17.1 28.3 0.0 11.2 11.8 5.9 12.4 5.5 12.3 18.5 8.7 9.7 11.3 0.0 16.6 1.7 7.6 0.5 9.5 0.0 7.4 5.9 14.2 24.3 8.2 14.3 6.0 8.0 24.6 8.0 11.6 13.6 0.0 14.9 11.2 5.3 9.2 10.0 24.4 0.1 9.4 0.0 16.5 0.0 3.4 9.8 0.0 6.3 0.0 3.2 9.0 18.8 2.7 13.2 14.8 12.6 5.8 10.6 7.3 0.2 0.0 15.3 10.7 24.1 7.6 0.0 3.1 3.3 1.1 2.8 0.9 1.7 1.2 1.4 2.3 1.3 0.8 0.7 0.3 0.7 2.5 2.2 0.7 0.6 3.7 6.4 0.0 4.3 6.4 3.1 0.6 0.9 1.0 0.2 1.5 1.8 61.7 32.1 51.1 21.2 18.8 10.8 6.8 11.9 11.4 5.5 9.9 8.1 20.2 15.7 15.0 20.2 0.0 65.2 21.5 36.6 7.9 18.6 80.5 51.2 46.2 31.2 24.6 6.1 171.0 23.4 16.8 35.2 41.8 41.7 7.6 36.1 8.2 26.1 21.0 0.0 90.0 32.3 4.1 29.6 19.3 177.8 45.1 34.7 8.8 301.7 32.7 13.0 10.3 281.0 41.2 38.4 39.3 20.3 11.6 8.0 11.9 9.4 57.1 13.7 26.3 46.7 32.7 7.5 12.9 17.6 18.3 118.3 19.0 19.0 32.5 6.0 DIO3 TXDI3 ENSG00000197406 "Iodothyronine deiodinase 3" P55073 14 101561351-101563452 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 25.0;placenta: 17.8" "Cell type enhanced" "Detected in some" "Endothelial cells: 7.8;Fibroblasts: 27.9;Leydig cells: 10.8;Muller glia cells: 8.1;Peritubular cells: 7.5;Skeletal myocytes: 16.3;Syncytiotrophoblasts: 28.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "AF22: 54.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "amygdala: 4.4;hippocampal formation: 5.6" HPA073684 Supported Vesicles NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA073684: " "unprognostic (4.52e-3)" "unprognostic (1.80e-1)" "unprognostic (3.04e-3)" "unprognostic (3.48e-1)" "unprognostic (5.16e-2)" "unprognostic (1.50e-1)" "unprognostic (4.24e-2)" "unprognostic (8.11e-2)" "unprognostic (2.58e-1)" "unprognostic (6.24e-2)" "unprognostic (2.34e-1)" "unprognostic (2.52e-1)" "unprognostic (7.46e-5)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (1.11e-4)" "unprognostic (9.80e-3)" 5.0 0.4 0.5 1.8 1.2 0.0 3.2 0.2 1.2 25.0 0.2 1.7 0.0 6.5 0.6 1.8 6.7 3.0 0.6 0.6 0.2 0.3 3.9 2.6 1.3 1.3 0.3 13.6 1.5 0.0 0.7 17.8 0.3 3.2 0.4 0.7 1.7 2.2 1.6 3.5 1.7 0.9 0.4 0.6 1.6 1.3 3.3 0.2 4.1 3.0 0.1 5.2 15.4 0.4 0.0 0.2 54.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.1 0.0 0.0 1.0 1.3 0.8 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.2 0.2 1.2 0.6 0.2 1.3 0.3 0.3 0.4 3.3 0.4 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.6 0.4 0.0 0.0 0.0 0.0 1.9 0.0 5.9 0.0 0.6 0.3 0.4 4.9 7.8 0.0 0.0 0.1 0.0 2.5 27.9 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.5 0.0 0.0 0.7 0.6 10.8 0.1 0.0 0.0 0.6 8.1 0.0 0.0 0.0 0.9 1.1 7.5 0.0 0.8 0.0 0.0 0.0 0.2 0.0 16.3 0.7 0.1 0.2 0.2 0.1 28.3 0.2 0.1 0.3 0.4 DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 884.3;Muller glia cells: 1960.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "BJ: 418.9;BJ hTERT+: 643.0;fHDF/TERT166: 614.4;hTERT-RPE1: 370.2;TIME: 349.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" 31.2 79.1 110.7 10.0 183.6 0.2 26.0 12.6 135.2 89.7 104.8 53.2 14.6 47.0 16.7 29.7 23.0 67.0 1224.0 147.7 80.2 17.0 5.6 123.7 8.5 95.1 54.3 38.1 18.2 34.2 38.2 25.0 46.8 59.4 13.0 204.1 30.9 78.1 7.8 29.7 24.6 43.1 83.9 33.2 31.7 30.9 99.9 4.7 16.4 18.8 5.4 40.9 48.3 121.6 1.5 13.1 18.1 0.1 15.3 29.7 0.6 418.9 643.0 182.4 205.5 9.6 3.2 0.0 44.8 614.4 96.8 64.4 1.5 181.9 69.5 0.1 0.5 0.0 1.7 0.0 113.6 0.0 0.3 45.3 60.0 61.9 151.3 370.2 195.3 0.0 0.2 0.4 256.4 0.0 0.1 0.4 8.6 0.0 0.5 0.1 1.2 0.1 62.5 0.6 0.5 53.2 2.0 0.0 0.2 47.9 0.2 0.5 349.7 107.5 82.8 11.2 110.3 0.1 0.0 0.3 18.1 0.0 103.5 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.6 3.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 110.7 183.6 12.6 135.2 147.7 80.2 95.1 54.3 46.8 83.9 99.9 121.6 5.8 3.2 3.0 94.3 0.1 45.6 59.5 70.3 93.4 31.6 3.2 103.2 884.3 0.0 12.8 0.0 12.5 0.5 0.4 0.0 0.0 0.8 104.3 0.7 8.4 32.9 1.8 0.0 90.4 0.2 0.8 106.1 7.1 0.6 1.3 17.0 66.8 0.4 20.4 13.5 83.7 0.1 0.0 1.3 12.5 88.5 20.5 1.4 64.0 38.4 0.0 1960.4 0.0 27.6 14.7 1.1 0.1 57.6 1.7 32.8 0.0 0.2 2.9 67.5 190.7 12.7 83.4 1.2 3.2 5.8 14.8 0.8 4.1 0.5 0.3 3.0 DMPK "DM, DM1, DM1PK, DMK, MDPK, MT-PK" ENSG00000104936 "DM1 protein kinase" Q09013 19 45769709-45782552 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 44.1;Sertoli cells: 59.2;Smooth muscle cells: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 85.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 8.7" "HPA007164, HPA008905" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol Vesicles "HPA007164: AB_1078687, HPA008905: AB_1078685" "unprognostic (7.44e-2)" "unprognostic (2.66e-1)" "unprognostic (1.76e-3)" "unprognostic (2.61e-3)" "unprognostic (1.29e-1)" "unprognostic (5.46e-2)" "unprognostic (8.67e-2)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-1)" "prognostic favorable (9.39e-5)" "unprognostic (1.93e-1)" "unprognostic (1.60e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (4.24e-3)" 24.2 68.3 22.1 17.5 24.0 3.0 19.1 22.2 33.1 42.8 25.6 121.5 15.8 92.7 5.3 33.4 61.2 13.9 171.3 21.8 21.6 20.3 8.8 29.8 5.2 24.0 23.8 31.1 34.3 2.9 37.9 8.8 22.3 56.4 4.8 4.1 18.6 37.6 173.6 12.3 34.6 59.9 21.9 17.8 51.7 13.2 23.8 4.2 21.7 143.2 1.3 69.1 34.3 21.3 11.7 16.7 13.5 10.7 13.4 12.9 10.5 26.1 22.2 10.5 8.8 2.2 6.6 2.9 2.8 32.9 9.2 15.1 3.0 1.5 2.2 12.4 16.6 0.8 22.6 1.4 12.6 0.1 5.4 22.8 8.0 6.4 1.7 24.2 3.6 2.1 8.6 8.0 15.4 13.7 1.6 3.8 8.8 4.8 3.3 5.0 85.1 6.4 4.7 11.5 10.2 13.5 13.6 27.6 9.3 4.8 28.6 5.5 8.4 9.2 10.4 8.3 15.0 16.8 11.5 2.9 9.5 1.3 13.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 24.0 22.2 33.1 21.8 21.6 24.0 23.8 22.3 21.9 23.8 21.3 10.5 0.0 2.2 44.1 3.7 8.0 8.1 3.8 5.7 5.7 9.6 9.9 3.7 4.3 3.2 3.7 8.4 2.7 4.2 4.7 1.9 2.7 1.5 8.7 8.6 7.9 10.1 0.4 16.4 17.3 2.0 8.4 8.2 6.3 0.0 9.7 9.3 1.5 0.8 5.0 12.4 8.2 8.2 1.6 9.8 1.8 7.2 0.8 7.2 10.3 0.4 2.6 5.2 26.7 10.0 5.8 4.5 23.3 3.1 4.0 3.8 31.7 7.1 7.4 59.2 27.6 34.9 7.2 6.4 10.1 6.8 1.6 4.5 5.4 5.1 4.6 DNAJC13 "KIAA0678, RME8" ENSG00000138246 "DnaJ heat shock protein family (Hsp40) member C13" O75165 3 132417502-132539032 "Human disease related genes, Predicted membrane proteins" "Protein transport, Transport" Chaperone "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036923, HPA036924" Approved Supported Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" Vesicles Cytosol "HPA036923: AB_10672480, HPA036924: AB_2675386" "unprognostic (3.35e-3)" "unprognostic (7.47e-2)" "unprognostic (9.16e-2)" "unprognostic (1.20e-2)" "unprognostic (9.71e-2)" "unprognostic (4.92e-2)" "prognostic unfavorable (7.49e-4)" "unprognostic (3.68e-2)" "unprognostic (3.38e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (8.36e-4)" "unprognostic (1.92e-1)" "unprognostic (4.81e-3)" "unprognostic (2.15e-1)" "unprognostic (1.71e-1)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" 11.7 9.4 5.9 12.4 6.5 15.5 11.4 6.0 6.3 12.9 8.2 14.4 10.9 13.8 11.7 10.7 9.9 9.9 12.9 5.9 6.9 16.0 9.8 11.3 11.0 7.7 6.9 11.7 6.8 12.6 5.9 15.4 7.1 10.8 14.3 10.7 9.1 12.1 12.5 9.8 10.4 16.7 6.3 12.2 9.7 7.8 7.5 12.0 15.7 14.2 10.6 12.4 10.3 7.8 31.0 18.0 22.2 10.9 54.3 46.7 13.7 32.3 62.5 31.4 33.8 20.4 18.2 15.7 20.5 46.3 41.1 24.1 22.1 24.3 43.5 18.3 6.4 20.6 17.1 13.6 27.6 21.1 18.3 34.2 16.4 28.5 35.1 22.7 44.6 26.0 11.4 25.6 43.7 24.1 16.8 9.1 12.7 26.7 15.8 15.9 16.5 13.0 27.7 32.4 7.9 11.9 31.6 16.7 36.1 19.0 24.7 17.8 40.9 34.7 17.8 33.3 13.9 14.8 15.7 21.5 36.8 13.6 25.2 2.0 2.6 0.4 0.8 2.2 0.7 1.0 0.9 0.7 2.8 0.4 0.6 0.8 0.5 0.7 4.0 1.4 0.4 0.8 5.9 6.5 6.0 6.3 5.9 6.9 7.7 6.9 7.1 6.3 7.5 7.8 16.8 12.8 21.9 45.7 14.4 6.6 7.3 7.3 6.8 10.8 8.9 7.2 47.2 8.6 11.3 12.9 33.3 7.9 13.2 21.5 1.9 9.0 1.7 10.3 31.3 17.1 14.4 12.8 48.7 9.1 7.7 20.2 16.8 18.7 12.0 18.9 13.2 8.5 20.5 67.3 48.7 12.5 0.0 34.2 9.2 3.6 15.2 26.5 28.4 60.0 25.1 13.3 6.2 46.8 64.7 11.7 12.5 21.4 13.9 10.5 17.0 18.7 13.1 11.5 6.6 22.3 19.7 5.3 13.7 15.4 7.5 5.1 10.8 22.5 13.4 11.0 DNASE1 DNL1 ENSG00000213918 "Deoxyribonuclease 1" P24855 16 3611728-3680143 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Actin-binding, Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 34.5;kidney: 34.2" "Cell type enriched" "Detected in many" 11 "Proximal enterocytes: 715.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010703 Enhanced Supported Vesicles "Secreted in other tissues" NA NA 420000 "Cluster 49: Eosinophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA010703: AB_10600806" "unprognostic (5.18e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (2.38e-1)" "unprognostic (1.90e-2)" "unprognostic (3.73e-2)" "unprognostic (3.82e-1)" "unprognostic (3.20e-1)" "unprognostic (9.91e-2)" "unprognostic (1.69e-3)" "unprognostic (5.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.14e-4)" 4.6 5.0 5.1 6.6 5.6 4.3 4.6 13.4 6.4 9.8 6.9 6.1 29.7 5.2 5.0 7.1 6.8 2.7 5.5 5.8 4.9 34.2 5.9 4.9 10.0 6.0 5.2 7.5 23.6 2.7 16.3 4.2 6.6 11.6 5.0 4.4 4.9 2.5 3.7 7.8 34.5 2.7 3.2 9.2 11.2 9.2 5.8 9.4 7.4 1.3 8.7 6.0 8.5 9.7 2.9 6.5 11.4 5.9 3.3 2.8 5.2 4.7 0.8 3.7 5.3 8.0 6.9 12.3 3.6 0.7 7.8 4.8 4.2 1.3 3.9 5.5 6.4 4.4 11.3 5.4 1.7 2.9 9.6 2.3 4.8 5.0 1.2 5.8 2.5 10.3 11.2 5.0 3.2 12.3 6.3 13.6 6.9 8.7 3.6 14.9 5.3 5.7 3.1 2.5 8.1 7.6 3.5 10.5 1.9 5.7 10.4 7.7 3.4 6.8 5.0 4.3 2.5 4.8 7.5 21.4 1.7 5.7 6.6 2.7 1.1 3.2 1.5 0.7 1.0 1.4 1.2 1.3 0.6 2.1 1.3 1.8 5.0 1.0 0.7 1.1 1.4 0.5 5.1 5.6 13.4 6.4 5.8 4.9 6.0 5.2 6.6 3.2 5.8 9.7 4.9 9.6 10.3 27.1 9.1 2.7 8.6 3.1 10.8 27.3 5.5 4.8 6.0 4.3 9.7 16.5 22.9 8.6 9.3 11.8 56.7 5.3 19.3 9.8 10.0 7.7 14.3 7.6 20.5 11.0 4.1 7.4 13.3 8.4 2.5 23.3 7.5 1.8 3.9 25.2 22.0 38.6 20.3 5.0 4.2 52.4 8.4 4.4 1.8 15.9 13.2 8.6 30.9 22.1 20.6 5.3 61.4 7.9 7.2 12.4 715.5 2.4 9.1 17.9 0.0 13.6 6.3 28.5 24.5 5.8 3.8 6.2 12.2 10.4 33.4 6.3 DNM1L "DRP1, DVLP, DYMPLE, HDYNIV, VPS1" ENSG00000087470 "Dynamin 1 like" O00429 12 32679200-32745650 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Biological rhythms, Endocytosis, Necrosis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009952, HPA039324" Approved Enhanced Vesicles,Cytosol NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol Vesicles "CAB009952: AB_2093533, HPA039324: AB_2676443" "unprognostic (2.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.10e-3)" "unprognostic (1.12e-1)" "unprognostic (5.09e-1)" "unprognostic (4.06e-2)" "prognostic unfavorable (6.27e-6)" "unprognostic (8.68e-2)" "unprognostic (2.25e-2)" "unprognostic (1.04e-2)" "unprognostic (1.71e-1)" "unprognostic (2.63e-1)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (8.17e-2)" "unprognostic (7.48e-2)" "unprognostic (1.57e-2)" 23.2 23.2 25.3 23.5 27.5 40.0 21.1 27.7 32.3 18.4 15.7 24.0 18.6 23.6 23.9 28.6 19.8 17.5 38.9 28.4 26.1 27.9 14.2 16.7 20.9 22.5 22.0 20.0 13.5 40.5 25.3 23.9 23.6 27.0 22.7 44.9 16.0 28.7 43.8 18.3 16.8 32.0 22.2 18.8 17.3 36.0 21.6 21.4 22.4 57.2 24.8 29.9 18.5 26.6 66.8 62.3 64.3 68.3 51.2 52.7 123.2 72.0 55.4 67.2 61.7 80.6 48.0 87.3 50.0 65.8 66.9 57.8 69.2 80.3 79.3 46.6 57.6 102.3 57.2 48.2 41.7 72.5 50.1 48.6 37.4 70.7 66.1 63.5 81.1 41.4 74.4 37.5 75.3 21.7 29.1 61.7 138.2 41.0 30.8 48.6 125.0 61.5 56.5 79.1 57.1 59.3 76.3 51.8 56.7 129.4 59.7 49.0 74.0 57.3 54.4 135.3 68.2 26.1 75.8 86.3 55.6 47.0 43.5 7.4 10.0 3.2 5.6 15.6 6.9 7.0 6.2 6.1 18.8 6.0 7.3 8.4 1.8 8.1 15.6 5.6 7.3 7.9 25.3 27.5 27.7 32.3 28.4 26.1 22.5 22.0 23.6 22.2 21.6 26.6 42.5 38.5 38.4 82.6 36.0 30.0 34.7 28.0 44.3 80.9 32.5 29.2 82.8 20.0 33.3 25.8 131.3 30.0 53.8 26.7 31.3 34.8 63.9 38.8 55.8 42.0 30.5 28.4 139.4 25.1 63.7 41.0 23.9 59.4 50.7 48.8 26.4 16.0 30.8 126.2 150.0 24.9 34.6 27.5 30.7 78.0 26.8 43.3 14.2 44.0 45.6 59.0 34.0 99.5 121.7 45.7 14.4 30.5 48.5 42.8 11.4 23.3 22.8 164.8 19.7 55.0 55.5 79.3 52.3 39.6 27.6 36.0 42.2 26.0 31.5 36.4 EEA1 ZFYVE2 ENSG00000102189 "Early endosome antigen 1" Q15075 12 92770637-92929331 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005861, CAB018782, HPA038158, HPA038159" Supported Supported Vesicles NA NA 20000 "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB005861: AB_2262056, CAB018782: AB_2277714, HPA038158: AB_10966710, HPA038159: AB_10962356" "unprognostic (5.38e-2)" "unprognostic (4.60e-1)" "unprognostic (2.00e-2)" "unprognostic (5.62e-2)" "unprognostic (1.62e-1)" "unprognostic (1.81e-2)" "unprognostic (6.75e-2)" "unprognostic (6.87e-2)" "unprognostic (1.31e-1)" "unprognostic (5.00e-2)" "unprognostic (2.81e-2)" "unprognostic (1.07e-1)" "unprognostic (2.68e-3)" "unprognostic (5.86e-2)" "unprognostic (2.85e-1)" "unprognostic (3.89e-2)" "unprognostic (1.65e-1)" 11.4 6.6 2.8 6.7 3.0 3.7 7.2 6.6 4.3 9.3 0.0 8.2 6.7 8.7 4.1 13.1 4.8 7.3 7.8 2.7 3.8 6.6 9.5 7.1 5.6 5.3 4.3 8.9 6.0 8.1 2.8 9.4 5.5 7.3 7.0 13.7 7.0 5.7 9.6 10.2 6.6 8.4 3.2 7.3 7.0 5.3 3.5 4.1 8.1 10.4 5.5 8.5 6.8 4.4 14.9 4.9 7.2 5.1 30.1 30.1 16.4 28.8 16.6 15.0 10.6 17.1 4.0 15.2 5.1 20.3 21.3 17.5 16.0 8.1 23.0 10.2 7.8 16.2 5.9 15.7 16.7 11.6 7.3 19.7 11.7 16.1 24.0 16.7 25.3 4.2 12.2 5.0 15.7 6.9 8.4 7.9 7.2 6.0 10.5 9.2 18.2 10.1 7.7 20.4 6.0 4.4 21.2 13.7 12.9 9.9 18.2 10.1 34.4 21.0 8.0 16.8 11.2 5.4 10.1 10.2 7.8 10.1 11.6 0.0 0.6 0.2 0.4 0.4 0.4 0.5 0.4 0.4 0.5 0.4 0.8 0.5 0.5 0.2 0.9 0.5 0.1 0.2 2.8 3.0 6.6 4.3 2.7 3.8 5.3 4.3 5.5 3.2 3.5 4.4 58.3 99.3 59.8 60.7 36.4 37.9 57.6 25.2 35.9 53.1 26.5 24.9 93.0 17.2 32.8 25.8 37.5 65.5 39.4 35.7 43.0 59.0 15.1 37.1 85.7 58.9 16.8 14.9 58.5 34.7 45.8 81.1 29.0 53.6 32.9 29.8 31.4 37.4 36.4 183.4 76.2 26.6 14.2 38.6 36.8 9.5 61.8 44.5 48.0 68.4 44.0 60.0 28.8 94.5 102.5 40.4 35.9 68.1 19.8 50.0 26.3 35.3 26.4 68.4 46.0 104.4 71.0 131.1 30.0 91.3 50.3 113.6 29.8 35.5 30.7 78.1 EIF2B3 "EIF-2B, EIF2Bgamma" ENSG00000070785 "Eukaryotic translation initiation factor 2B subunit gamma" Q9NR50 1 44850522-44986722 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024213, HPA024218, HPA024219" Supported Supported Vesicles,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Vesicles, Cytosol" "HPA024213: AB_1848067, HPA024218: AB_1848068, HPA024219: AB_1848069" "unprognostic (2.12e-2)" "unprognostic (7.49e-2)" "unprognostic (4.37e-3)" "unprognostic (5.14e-2)" "unprognostic (1.57e-2)" "unprognostic (4.45e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (4.55e-2)" "unprognostic (1.14e-2)" "unprognostic (7.22e-2)" "unprognostic (2.16e-1)" "unprognostic (1.36e-1)" "unprognostic (5.38e-2)" "unprognostic (6.98e-2)" "unprognostic (7.80e-2)" "unprognostic (5.69e-3)" "unprognostic (2.73e-2)" 23.6 27.2 11.4 11.6 10.9 10.9 21.9 13.2 15.6 18.7 10.1 17.5 8.6 17.0 12.5 17.4 16.3 9.6 40.6 11.2 11.6 15.4 24.7 13.5 14.3 11.9 12.1 18.2 16.9 30.0 15.8 9.7 12.8 15.0 13.4 19.0 25.1 13.7 77.0 17.6 10.7 19.4 11.0 14.9 14.2 19.3 11.2 13.3 12.5 48.0 14.5 17.7 17.1 14.0 35.4 26.9 30.9 25.5 36.3 43.1 36.2 56.1 42.2 56.5 52.9 39.0 20.7 90.6 39.9 43.2 45.0 20.6 65.3 48.6 69.5 32.5 58.1 44.3 29.3 38.4 46.2 71.2 24.3 29.3 25.8 61.0 69.9 26.5 52.8 30.1 106.1 31.6 62.3 23.1 69.7 30.2 42.0 38.8 52.7 54.7 51.3 65.7 28.7 15.7 53.2 20.5 55.1 63.8 37.4 40.7 24.7 32.8 28.3 35.9 42.9 53.4 73.7 31.6 37.9 68.9 27.9 59.5 43.1 1.6 23.4 3.9 18.6 37.2 22.8 14.8 18.3 21.1 37.0 18.9 22.9 23.6 2.1 25.5 33.1 25.3 17.6 21.4 11.4 10.9 13.2 15.6 11.2 11.6 11.9 12.1 12.8 11.0 11.2 14.0 13.9 6.4 22.0 24.8 15.8 13.8 19.0 33.0 10.8 15.1 15.8 16.8 79.2 15.7 24.9 5.5 20.9 25.1 12.1 4.5 29.4 18.9 26.1 17.0 23.0 14.4 3.6 15.3 39.9 15.8 22.6 22.6 13.7 11.5 25.9 21.1 3.9 22.6 24.8 21.9 44.5 7.0 20.3 10.7 11.2 11.3 26.4 15.4 17.8 26.2 30.1 21.7 10.3 29.1 35.7 13.7 6.9 25.2 22.6 17.1 5.7 23.1 34.2 21.8 26.3 19.7 45.4 45.5 23.6 17.1 14.9 14.9 13.5 40.4 9.4 13.9 EIF5A2 ENSG00000163577 "Eukaryotic translation initiation factor 5A2" Q9GZV4 3 170888418-170908644 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein biosynthesis, Protein transport, Translocation, Transport" "Elongation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 28.3" "Group enriched" "Detected in many" 12 "Early spermatids: 353.0;Late spermatids: 977.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029090 Approved Supported Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA029090: AB_10671359" "unprognostic (2.41e-1)" "unprognostic (2.42e-1)" "unprognostic (4.05e-1)" "unprognostic (5.75e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (7.42e-4)" "unprognostic (1.11e-3)" "unprognostic (1.47e-1)" "unprognostic (3.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (1.79e-1)" "unprognostic (2.66e-2)" "unprognostic (3.45e-2)" "unprognostic (5.92e-2)" "unprognostic (1.64e-2)" "unprognostic (4.29e-3)" 4.1 2.7 1.9 3.1 2.8 4.2 2.9 5.8 6.1 3.1 1.9 3.4 1.7 4.5 1.3 2.9 2.4 3.5 4.0 1.9 5.4 5.0 1.6 2.2 2.8 7.2 4.6 4.4 3.3 3.7 1.8 1.8 8.2 2.6 2.6 2.8 1.9 3.0 1.3 1.9 1.6 7.2 4.1 2.3 9.1 28.3 5.5 4.3 2.2 3.1 3.1 3.5 2.0 7.2 22.7 11.6 4.2 5.9 21.7 14.2 10.0 17.1 22.3 17.4 25.1 23.6 14.4 14.2 30.9 23.4 38.9 7.4 13.4 6.0 21.9 15.8 5.8 6.9 4.6 7.5 14.6 18.2 19.9 16.6 8.7 26.3 21.4 24.2 9.1 3.7 5.8 0.1 28.7 7.6 8.1 7.9 8.1 17.5 7.8 0.0 12.0 0.0 7.3 4.0 3.4 6.4 17.7 4.6 14.4 6.5 10.0 11.9 12.0 21.2 15.0 44.8 38.9 21.6 0.3 33.3 7.2 6.2 15.4 14.9 1.4 1.5 12.4 1.5 8.7 2.2 8.4 11.9 1.0 3.5 5.0 8.3 0.7 8.8 1.4 1.0 11.3 5.0 1.9 2.8 5.8 6.1 1.9 5.4 7.2 4.6 8.2 4.1 5.5 7.2 16.6 0.0 0.5 4.9 4.4 17.1 8.5 7.8 10.8 2.5 2.1 2.7 9.5 0.0 1.8 1.8 0.0 1.2 18.1 1.6 1.9 6.4 353.0 0.9 7.7 12.8 4.9 2.1 7.1 7.5 1.9 11.7 8.6 0.6 2.5 2.6 3.3 2.5 8.9 0.0 8.8 0.8 2.0 3.8 7.2 977.9 12.8 4.5 10.6 3.7 7.9 8.0 28.8 4.0 10.1 19.6 6.1 11.3 3.7 8.2 1.7 21.1 3.4 2.7 46.0 9.6 11.6 54.3 10.0 2.3 21.6 0.7 15.7 2.2 1.8 5.7 EPN2 "EHB21, KIAA1065" ENSG00000072134 "Epsin 2" O95208 17 19215615-19336715 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Oligodendrocyte precursor cells: 868.6;Oligodendrocytes: 258.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.9;eosinophil: 29.0;neutrophil: 9.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 29.0" "Cell line enhanced" "Detected in many" "SuSa: 127.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049809, HPA053360" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA049809: AB_2680893, HPA053360: AB_2682126" "unprognostic (1.38e-2)" "unprognostic (2.54e-2)" "unprognostic (2.58e-2)" "unprognostic (2.09e-1)" "unprognostic (1.94e-1)" "unprognostic (8.12e-3)" "unprognostic (6.73e-3)" "unprognostic (1.43e-1)" "unprognostic (8.89e-2)" "unprognostic (4.58e-3)" "unprognostic (3.42e-2)" "unprognostic (1.57e-1)" "prognostic favorable (9.13e-5)" "unprognostic (1.32e-1)" "unprognostic (9.40e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (8.15e-5)" 20.5 13.9 62.1 9.7 64.9 11.5 16.7 50.4 62.8 36.3 32.7 28.3 9.6 29.5 11.5 40.3 26.6 14.6 32.5 62.6 56.2 21.3 9.3 18.6 6.5 61.6 63.6 22.5 14.6 15.3 18.1 21.6 57.5 23.6 9.5 19.1 17.9 23.4 22.4 50.1 13.3 22.5 46.6 14.3 15.9 19.7 63.6 4.7 17.8 17.0 8.4 27.0 33.8 91.6 31.3 30.4 43.9 19.2 22.8 36.3 34.5 29.4 18.9 17.9 15.3 20.2 9.2 4.9 28.2 29.5 16.8 29.0 19.8 22.1 21.9 23.6 21.2 3.2 20.3 9.2 23.7 1.4 13.1 20.5 19.5 28.3 22.7 23.2 38.8 6.6 8.6 3.9 15.8 22.5 1.3 2.1 11.1 41.3 19.8 7.1 18.8 8.1 21.0 8.6 13.0 28.8 20.9 13.9 14.7 127.9 21.0 4.0 35.6 19.7 22.3 30.9 12.9 6.7 4.3 3.9 54.0 0.5 31.1 10.9 1.3 29.0 1.6 0.8 1.2 3.0 1.1 1.3 0.5 3.4 1.3 1.2 9.0 0.7 1.0 0.6 1.0 0.7 62.1 64.9 50.4 62.8 62.6 56.2 61.6 63.6 57.5 46.6 63.6 91.6 60.0 54.5 29.3 74.4 13.7 24.1 36.6 21.2 43.9 68.3 32.8 33.4 44.5 25.8 25.0 38.6 47.9 27.6 3.3 7.2 27.4 22.5 36.8 69.2 35.0 42.5 6.0 13.5 51.3 8.4 39.8 36.1 15.8 40.6 14.0 37.3 15.0 10.4 8.4 35.3 45.0 16.8 10.2 5.1 6.2 72.7 46.6 5.9 5.4 54.4 1.6 38.3 2.1 868.6 258.3 23.3 14.9 39.5 14.4 32.0 7.0 14.2 43.2 82.3 26.3 50.5 63.7 45.8 38.3 63.9 48.9 21.9 7.4 35.0 7.8 40.1 EPN3 "FLJ20778, MGC129899" ENSG00000049283 "Epsin 3" Q9H201 17 50532682-50543750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 35.9;stomach 1: 37.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 77.9;Distal enterocytes: 27.6;Gastric mucus-secreting cells: 44.9;Intestinal goblet cells: 24.9;Squamous epithelial cells: 30.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 28.6;HBEC3-KT: 40.3;MCF7: 66.4;OE19: 62.8;RT4: 50.2;SK-BR-3: 25.8;T-47d: 57.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055546, HPA063224" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles Nucleoplasm "HPA055546: AB_2682844, HPA063224: AB_2684964" "unprognostic (1.91e-2)" "unprognostic (1.99e-2)" "unprognostic (2.41e-1)" "unprognostic (2.91e-2)" "unprognostic (1.25e-3)" "unprognostic (2.06e-1)" "unprognostic (5.70e-3)" "unprognostic (7.62e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" "unprognostic (6.66e-3)" "unprognostic (1.00e-2)" "prognostic favorable (1.53e-5)" "unprognostic (1.45e-1)" "unprognostic (1.16e-1)" "unprognostic (4.90e-1)" "unprognostic (3.52e-3)" 0.2 8.9 2.3 0.8 1.3 0.6 2.3 6.4 6.0 6.5 1.2 7.1 6.8 0.4 3.2 35.9 7.5 5.9 7.1 0.7 2.1 6.0 0.1 0.3 0.0 11.5 5.4 13.5 23.0 21.2 0.8 4.2 13.6 9.9 4.4 0.2 11.1 5.6 0.1 30.5 3.2 0.1 0.5 0.0 37.3 2.8 13.4 3.2 1.1 0.0 3.7 5.5 12.9 1.8 20.5 0.3 0.0 0.2 0.0 0.0 5.3 0.0 0.0 0.0 0.0 14.7 12.1 0.0 0.2 0.0 0.1 28.6 0.0 40.3 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.2 0.1 21.8 0.1 3.0 0.0 0.0 0.1 0.0 0.0 0.0 66.4 0.3 0.0 0.0 62.8 0.4 0.0 0.0 0.1 0.2 50.2 0.4 0.0 0.0 25.8 0.0 0.4 57.4 0.2 1.5 0.3 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.3 6.4 6.0 0.7 2.1 11.5 5.4 13.6 0.5 13.4 1.8 0.2 0.0 0.0 0.0 0.4 2.3 4.4 4.1 10.8 2.9 6.5 3.4 5.4 8.6 8.3 18.4 0.0 77.9 0.0 27.6 5.9 9.2 1.0 3.8 0.6 0.4 3.6 0.0 1.0 11.5 7.4 0.8 44.9 5.5 0.0 3.1 0.0 0.0 5.9 0.0 1.7 24.9 2.0 0.0 0.0 2.1 2.8 0.5 0.0 1.0 0.6 0.6 0.0 0.0 0.0 3.4 10.3 0.0 1.3 4.9 2.1 0.3 4.3 0.9 0.0 0.0 0.8 0.0 0.5 30.0 5.5 10.7 0.2 12.4 19.3 7.8 ERC1 "CAST2, ELKS, KIAA1081, MGC12974, RAB6IP2" ENSG00000082805 "ELKS/RAB6-interacting/CAST family member 1" Q8IUD2 12 990509-1495933 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 292.3;Horizontal cells: 185.1;Inhibitory neurons: 487.0;Microglial cells: 213.6;Oligodendrocyte precursor cells: 230.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019513, HPA019523, HPA024130" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Vesicles, Plasma membrane" "HPA019513: AB_1856012, HPA019523: AB_1856013, HPA024130: AB_1856014" "unprognostic (2.41e-1)" "unprognostic (4.00e-2)" "unprognostic (2.14e-1)" "unprognostic (5.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (5.50e-2)" "unprognostic (8.49e-2)" "unprognostic (2.53e-1)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (6.79e-2)" "unprognostic (3.75e-3)" "unprognostic (4.19e-2)" "unprognostic (3.01e-1)" "unprognostic (7.37e-2)" "prognostic unfavorable (7.01e-4)" 10.4 9.7 12.2 6.8 14.4 7.3 8.0 38.1 12.8 8.9 8.0 11.8 3.5 9.0 4.8 11.8 8.2 7.5 13.9 15.2 18.5 9.2 6.5 7.3 4.8 13.7 14.8 10.5 7.6 15.4 8.1 11.8 13.7 9.5 6.2 7.0 8.4 12.1 9.4 9.4 5.8 12.9 11.9 5.8 7.2 7.5 17.7 7.9 13.4 9.0 5.3 13.4 9.0 12.6 8.2 20.1 10.3 7.1 27.8 22.2 14.2 25.0 20.0 17.0 15.3 17.7 10.0 12.5 3.4 33.2 16.8 13.3 22.1 19.7 23.1 25.9 11.6 30.3 20.1 9.3 21.1 16.1 6.9 18.7 17.0 30.0 55.6 20.7 22.3 7.9 9.6 23.9 12.9 9.2 5.2 3.5 16.8 8.1 9.7 9.9 38.9 3.8 16.9 14.2 6.3 12.3 38.8 9.3 13.9 37.6 9.3 7.0 39.6 29.6 29.0 21.6 24.0 6.4 13.1 18.1 19.2 9.4 12.9 1.5 3.1 2.3 1.7 1.2 2.4 12.7 2.7 2.7 2.7 5.6 3.8 2.7 2.4 1.4 4.8 3.4 2.8 0.7 12.2 14.4 38.1 12.8 15.2 18.5 13.7 14.8 13.7 11.9 17.7 12.6 36.9 25.6 25.1 155.4 21.2 21.0 25.6 9.4 29.0 39.2 13.2 14.1 56.4 17.2 17.4 20.2 47.9 34.1 12.6 12.7 1.9 20.3 34.3 31.2 43.4 34.6 30.0 7.6 292.3 13.4 18.0 32.3 23.9 53.9 14.5 59.2 24.3 17.3 12.4 185.1 487.0 11.9 2.0 12.6 16.5 35.2 24.8 17.0 14.2 213.6 18.4 34.8 6.2 230.7 171.1 18.5 10.3 30.9 39.1 30.8 6.1 4.1 13.2 33.4 19.7 35.5 33.1 18.5 28.8 33.8 27.4 78.7 15.8 18.7 10.3 29.4 ERGIC2 "Erv41, PTX1" ENSG00000087502 "ERGIC and golgi 2" Q96RQ1 12 29337352-29381189 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 383.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049695 Approved Supported "Nucleoli rim,Golgi apparatus,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "Nucleoli rim" "HPA049695: AB_2680855" "unprognostic (1.62e-2)" "unprognostic (3.50e-2)" "unprognostic (5.53e-2)" "unprognostic (3.56e-1)" "unprognostic (1.45e-1)" "unprognostic (5.19e-3)" "prognostic unfavorable (8.06e-6)" "unprognostic (3.70e-2)" "unprognostic (2.32e-2)" "prognostic favorable (8.18e-4)" "prognostic unfavorable (7.02e-6)" "unprognostic (2.67e-1)" "prognostic unfavorable (3.76e-6)" "unprognostic (6.02e-2)" "unprognostic (2.08e-1)" "unprognostic (3.19e-2)" "unprognostic (2.64e-1)" 38.5 32.5 22.7 37.8 24.6 10.5 46.0 25.1 29.0 34.4 20.8 37.1 34.4 34.4 50.1 46.0 24.2 33.1 52.4 22.6 25.9 30.6 47.6 26.3 33.8 24.9 23.9 26.9 40.2 47.2 20.7 53.1 24.3 39.5 33.7 29.4 49.2 34.5 33.8 19.2 34.9 39.3 25.4 26.7 32.6 57.8 24.4 35.0 45.1 47.0 43.6 50.1 22.1 34.4 96.7 87.0 69.1 46.8 94.8 111.5 170.1 153.1 123.4 92.7 98.3 115.7 157.6 51.3 149.1 120.7 168.7 98.7 66.0 98.3 146.4 112.6 69.4 84.0 114.6 68.3 55.7 121.2 70.0 79.1 75.9 115.8 116.7 169.3 71.8 69.8 70.5 144.6 122.6 52.3 60.3 126.2 98.9 101.3 235.0 54.9 189.9 107.6 75.5 140.1 26.5 43.2 77.2 86.5 91.5 145.9 168.0 96.7 81.8 124.1 108.1 169.1 167.6 106.4 145.5 106.0 103.7 87.3 105.3 92.3 50.2 70.6 84.7 79.9 102.9 83.2 107.6 101.2 55.1 71.0 106.6 90.3 181.1 72.1 101.1 120.9 130.8 90.1 22.7 24.6 25.1 29.0 22.6 25.9 24.9 23.9 24.3 25.4 24.4 34.4 54.6 28.9 28.6 20.9 74.3 57.9 68.9 144.1 39.9 54.8 57.2 55.1 61.7 38.6 99.0 53.3 54.2 119.2 60.8 19.4 49.0 72.7 383.0 48.7 66.5 43.7 41.8 44.8 39.2 62.8 120.6 73.0 25.5 54.6 55.8 44.2 34.6 50.2 56.4 48.8 37.8 33.5 87.5 25.5 40.2 51.9 52.5 37.1 62.2 14.0 41.6 69.5 52.5 32.2 48.3 58.1 20.5 59.8 154.0 85.7 32.4 49.5 64.6 60.0 32.9 58.5 105.7 75.0 36.3 49.4 66.3 156.2 68.0 54.0 34.7 78.8 ESPL1 "ESP1, KIAA0165, SEPA" ENSG00000135476 "Extra spindle pole bodies like 1, separase" Q14674 12 53268299-53293638 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Chromosome partition" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.5;esophagus: 15.4;lymphoid tissue: 10.7" "Cell type enhanced" "Detected in many" "Ionocytes: 22.4;Proximal enterocytes: 22.6;Squamous epithelial cells: 7.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB012185, HPA073188" Approved Supported Nucleoplasm,Vesicles NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Vesicles "CAB012185: AB_304056, HPA073188: " "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.01e-5)" "prognostic unfavorable (7.14e-4)" "unprognostic (1.59e-2)" "unprognostic (2.48e-1)" "unprognostic (4.17e-3)" "unprognostic (1.18e-2)" "unprognostic (7.42e-13)" "prognostic favorable (7.10e-4)" "unprognostic (2.39e-1)" "unprognostic (7.41e-2)" "unprognostic (1.42e-1)" 0.4 0.2 0.0 2.4 0.0 8.5 0.5 0.0 0.0 3.5 0.0 1.5 3.9 0.2 0.0 15.4 0.2 0.4 0.1 0.0 0.0 0.9 0.6 0.4 4.4 0.0 0.0 0.1 0.1 0.0 0.0 1.1 0.0 0.1 1.4 0.0 2.0 0.1 0.0 2.6 4.3 0.7 0.0 1.0 0.9 6.2 0.1 10.7 0.1 0.0 4.9 0.6 5.9 0.0 27.8 23.6 27.6 21.1 0.6 1.9 17.5 15.9 8.6 28.8 19.2 15.8 22.7 49.9 9.5 6.8 17.4 20.2 32.6 9.9 14.3 13.7 32.8 30.6 24.1 11.1 0.1 19.5 25.2 0.6 0.6 15.5 7.6 2.8 15.4 22.2 42.6 41.0 9.1 29.2 30.6 16.4 22.5 14.5 12.9 29.3 30.2 21.4 4.2 11.6 18.9 15.8 11.9 20.4 10.1 13.0 36.9 12.7 8.2 14.5 27.2 11.9 25.5 32.5 29.7 31.9 8.2 19.0 27.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.3 0.6 0.9 0.3 0.5 0.6 0.0 1.0 1.3 0.9 0.0 0.4 3.7 0.0 1.9 0.6 2.7 0.0 0.2 0.8 0.2 0.8 1.0 3.5 1.3 0.7 0.0 2.3 1.1 3.6 0.7 0.0 4.4 0.7 6.8 2.6 0.0 0.4 2.7 22.4 0.6 2.1 1.2 0.0 1.3 0.0 1.0 0.0 0.0 0.0 0.0 0.5 1.5 1.3 0.4 2.1 0.4 22.6 6.6 0.2 0.0 0.0 0.4 0.9 5.5 4.1 7.4 0.6 0.3 0.4 0.1 2.8 0.4 EVA1A "FAM176A, FLJ13391, TMEM166" ENSG00000115363 "Eva-1 homolog A, regulator of programmed cell death" Q9H8M9 2 75469302-75569722 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 191.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Cytotrophoblasts: 43.3;Hepatocytes: 78.1;Proximal tubular cells: 77.3;Syncytiotrophoblasts: 124.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 85.7;U-138 MG: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008055 Approved Supported "Vesicles,Plasma membrane" NA Yes "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Plasma membrane" "HPA008055: AB_1080308" "unprognostic (2.72e-1)" "unprognostic (2.61e-2)" "unprognostic (4.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.60e-2)" "unprognostic (5.02e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "prognostic favorable (5.67e-4)" "unprognostic (7.33e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.80e-4)" "unprognostic (8.19e-2)" "unprognostic (4.37e-2)" "unprognostic (2.43e-2)" "unprognostic (9.07e-2)" 1.1 0.5 0.2 1.1 0.9 0.1 3.4 0.6 0.5 9.8 0.2 0.7 1.7 2.8 9.6 0.4 3.7 1.2 1.6 0.2 0.3 20.0 191.6 20.7 0.4 1.1 0.5 0.5 23.8 7.6 1.1 17.3 0.9 0.9 0.7 0.5 8.9 2.2 1.2 2.7 1.8 2.0 0.7 10.8 0.6 2.9 0.8 5.1 1.8 1.6 0.3 0.8 0.8 0.8 1.0 14.5 1.5 0.4 3.1 21.2 1.4 68.0 45.3 59.2 30.1 0.5 1.2 0.1 6.3 85.7 54.2 9.4 1.7 14.4 36.8 0.0 1.1 0.0 2.5 45.7 2.2 0.0 0.1 15.0 8.3 73.2 33.3 59.0 37.2 0.0 0.0 0.0 46.1 0.0 0.1 0.0 3.3 0.2 23.5 7.9 0.1 0.0 32.5 0.5 0.9 1.6 6.2 0.4 53.7 2.2 0.2 0.3 31.0 110.3 46.3 2.0 71.9 0.7 0.1 0.3 62.5 0.0 59.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.6 0.5 0.2 0.3 1.1 0.5 0.9 0.7 0.8 0.8 6.1 41.7 35.4 1.0 0.9 2.8 13.7 14.3 3.4 1.2 11.7 12.3 0.3 1.5 23.0 11.0 0.0 43.3 0.4 0.1 27.4 30.5 12.2 13.3 1.4 4.8 1.8 0.0 1.1 16.1 25.9 4.7 0.0 11.4 0.0 0.0 2.2 78.1 3.5 0.0 0.9 1.1 4.1 0.8 1.2 9.4 0.3 0.6 28.4 2.8 0.1 0.0 0.0 1.5 0.9 9.7 0.0 0.7 0.0 12.3 0.5 77.3 1.7 0.1 0.0 2.2 9.0 2.2 0.9 1.1 0.9 124.8 1.1 0.0 1.6 10.5 EXOC6 "DKFZp761I2124, EXOC6A, FLJ1125, MGC33397, SEC15L, SEC15L1, Sec15p" ENSG00000138190 "Exocyst complex component 6" Q8TAG9 10 92826831-93059493 "Plasma proteins, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "retina: 164.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 181.7;Microglial cells: 146.1;Oligodendrocyte precursor cells: 157.3;Rod photoreceptor cells: 177.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036285, HPA059111" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "HPA036285: AB_10673617, HPA059111: AB_2683907" "unprognostic (1.41e-1)" "unprognostic (1.39e-3)" "unprognostic (5.20e-2)" "unprognostic (2.65e-1)" "unprognostic (1.10e-1)" "unprognostic (1.64e-1)" "unprognostic (1.16e-3)" "unprognostic (7.21e-3)" "unprognostic (3.84e-1)" "unprognostic (2.70e-1)" "unprognostic (1.66e-1)" "unprognostic (8.13e-2)" "prognostic favorable (4.66e-4)" "unprognostic (2.12e-2)" "unprognostic (1.00e-1)" "unprognostic (1.42e-1)" "unprognostic (6.41e-2)" 8.7 14.4 5.9 8.2 7.5 12.9 8.0 7.7 8.6 6.5 8.0 9.6 8.1 6.1 5.7 4.2 5.8 10.1 7.1 8.2 6.0 6.4 10.1 10.7 9.5 3.4 2.4 3.9 10.0 6.3 6.1 37.4 3.7 8.6 10.2 164.2 5.6 4.3 31.8 5.0 9.5 7.7 3.3 9.1 7.0 9.9 6.1 8.5 28.4 19.7 8.2 10.1 3.5 7.1 19.8 24.3 25.7 16.8 1.3 1.6 9.1 9.0 24.9 8.1 9.7 9.1 16.5 22.5 19.0 4.3 6.6 12.3 20.8 5.7 10.1 20.1 20.9 35.1 8.3 11.7 9.6 36.4 30.6 2.2 3.0 7.2 4.8 14.6 113.8 14.6 29.2 14.5 4.0 10.7 15.3 23.2 3.5 40.2 7.0 22.5 11.2 11.6 17.4 13.2 8.5 11.9 9.2 9.2 11.8 6.4 18.2 18.8 22.4 0.6 8.2 7.5 14.7 10.8 12.4 18.1 2.8 41.6 9.3 6.2 4.9 15.2 3.0 3.9 3.0 6.7 3.4 2.8 5.1 6.6 2.7 3.2 30.6 2.8 3.9 11.1 3.3 2.4 5.9 7.5 7.7 8.6 8.2 6.0 3.4 2.4 3.7 3.3 6.1 7.1 28.3 16.0 16.7 33.6 27.6 3.3 10.7 8.6 3.4 40.2 9.8 6.5 12.0 20.0 15.0 16.5 39.6 22.9 24.1 14.3 5.9 28.3 5.4 8.8 3.0 53.1 25.6 39.2 181.7 15.4 7.8 7.8 13.7 16.5 10.8 24.3 77.1 14.2 21.4 23.5 100.3 16.6 14.2 18.2 12.5 12.6 4.4 18.9 5.4 146.1 22.8 27.1 19.6 157.3 84.7 14.1 10.3 14.7 13.8 14.1 10.8 8.4 10.0 177.8 13.1 13.6 9.0 25.0 25.5 4.9 4.8 20.5 18.4 29.8 11.9 15.8 FBXW7 "AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10" ENSG00000109670 "F-box and WD repeat domain containing 7" Q969H0 4 152320544-152536092 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.9" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 201.8;Excitatory neurons: 529.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 23.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013793, CAB029987" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "CAB013793: AB_2533451, CAB029987: AB_2246842" "unprognostic (3.32e-1)" "unprognostic (9.02e-2)" "unprognostic (1.84e-2)" "unprognostic (3.08e-2)" "unprognostic (3.87e-1)" "unprognostic (1.36e-3)" "unprognostic (4.37e-1)" "unprognostic (1.94e-1)" "unprognostic (8.28e-2)" "unprognostic (3.29e-1)" "unprognostic (5.32e-3)" "unprognostic (3.19e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (3.38e-2)" "unprognostic (1.41e-1)" "unprognostic (5.49e-3)" "unprognostic (2.17e-3)" 14.2 9.5 37.9 15.0 43.1 19.8 14.2 54.3 66.9 8.7 6.7 9.5 7.8 8.6 24.3 14.3 15.6 9.2 24.7 48.2 23.0 6.7 11.2 11.4 16.1 17.1 20.9 9.1 12.8 7.8 9.2 9.4 18.1 7.8 10.3 18.0 11.8 7.5 26.0 63.1 10.4 9.1 11.8 16.2 13.0 22.8 29.4 14.7 10.3 19.7 20.3 11.9 10.7 47.4 9.8 8.0 19.1 14.2 12.2 9.4 16.2 13.4 12.9 8.5 8.1 15.7 12.0 24.7 3.9 13.7 6.5 5.2 16.9 30.9 12.1 16.2 8.0 11.9 10.7 10.9 12.7 29.2 10.6 14.8 45.7 15.2 24.4 8.4 15.2 20.5 19.2 25.7 10.8 13.7 34.9 10.6 9.7 8.0 6.1 32.2 8.0 5.3 9.8 17.0 12.7 10.2 8.5 11.3 7.5 21.6 6.4 12.6 15.6 11.3 12.6 5.4 8.2 79.0 47.5 24.4 9.4 9.2 8.3 23.5 2.7 1.6 4.0 3.0 2.7 2.8 3.1 2.7 1.6 1.8 3.4 2.5 4.8 7.1 2.2 2.1 2.9 1.3 37.9 43.1 54.3 66.9 48.2 23.0 17.1 20.9 18.1 11.8 29.4 47.4 29.5 9.6 22.9 80.0 48.1 201.8 36.5 29.9 120.1 74.9 32.1 30.9 61.8 12.8 15.1 9.2 31.3 10.9 54.7 22.2 3.9 14.3 17.4 37.7 37.3 36.1 14.5 30.1 529.6 13.5 39.9 27.2 21.4 61.6 15.8 19.1 17.9 18.3 10.5 11.8 186.5 16.4 32.6 18.8 47.0 10.2 15.2 33.7 28.4 172.4 28.0 37.0 35.0 102.5 99.8 18.7 18.2 11.3 174.5 36.3 8.9 7.5 11.9 41.4 13.1 33.2 25.5 74.1 87.2 57.0 174.9 31.2 46.2 18.7 14.9 70.5 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 273.8;choroid plexus: 198.1" "Group enriched" "Detected in many" 5 "Astrocytes: 228.2;Cholangiocytes: 213.1;Oligodendrocytes: 562.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 13.2;eosinophil: 3.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 13.2" "Cell line enhanced" "Detected in many" "AN3-CA: 189.0;BEWO: 60.9;CACO-2: 49.6;HaCaT: 55.6;HAP1: 63.7;NTERA-2: 57.8;T-47d: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" NA NA 1200000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 5.7 21.3 103.9 8.2 186.8 0.3 22.9 178.9 198.9 19.7 198.1 44.8 10.4 54.6 15.3 25.2 29.6 31.3 5.6 109.9 124.7 26.3 41.0 30.9 2.9 250.9 185.9 18.0 31.0 61.0 6.8 15.7 220.5 27.4 21.2 1.2 59.1 54.6 0.5 109.3 12.2 43.6 165.5 0.8 22.5 7.6 148.0 10.1 54.6 0.2 9.1 16.6 27.4 273.8 7.2 0.4 30.2 189.0 0.1 0.0 60.9 0.4 0.0 0.0 0.0 49.6 1.1 0.1 12.5 2.8 0.1 55.6 63.7 13.0 0.0 0.1 12.7 0.0 0.2 1.2 1.5 0.2 11.7 0.1 26.2 0.0 0.6 0.0 0.0 0.3 0.2 0.2 0.0 11.7 0.2 0.1 57.8 8.7 0.0 0.1 0.0 7.5 18.0 15.8 0.5 0.5 0.4 33.4 0.0 36.6 49.3 0.0 0.1 0.3 8.5 0.2 0.7 0.1 0.1 0.0 0.3 0.0 0.5 13.2 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 103.9 186.8 178.9 198.9 109.9 124.7 250.9 185.9 220.5 165.5 148.0 273.8 1.4 19.2 36.0 228.2 0.6 40.1 34.3 18.4 58.6 0.2 8.7 25.4 9.1 213.1 38.4 36.8 0.0 16.5 0.3 7.3 0.0 7.4 4.1 28.1 4.4 1.0 2.4 2.7 14.8 0.2 3.0 9.0 13.3 53.1 0.0 0.1 1.8 5.0 2.3 0.0 31.2 40.8 10.2 0.6 4.4 9.6 1.2 1.1 5.4 10.3 0.6 2.0 1.0 6.0 562.5 0.7 3.0 6.0 0.1 15.0 1.8 13.6 15.3 0.2 0.0 1.6 2.6 0.7 9.9 18.7 27.7 4.0 1.5 0.4 3.8 31.4 FGFRL1 ENSG00000127418 "Fibroblast growth factor receptor like 1" Q8N441 4 1009936-1026898 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 34.0;Granulosa cells: 30.9;Hepatocytes: 37.5;Muller glia cells: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.1;non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-251 MG: 99.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026019, HPA068828" Approved Supported Vesicles No No "Cluster 7: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Vesicles "CAB026019: , HPA068828: AB_2686043" "unprognostic (1.30e-2)" "unprognostic (2.54e-2)" "unprognostic (6.27e-2)" "unprognostic (2.80e-2)" "unprognostic (1.23e-2)" "unprognostic (1.48e-1)" "unprognostic (2.62e-2)" "unprognostic (9.79e-2)" "unprognostic (4.87e-3)" "unprognostic (8.46e-2)" "unprognostic (2.01e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-3)" "unprognostic (1.49e-1)" "unprognostic (7.80e-2)" "unprognostic (1.06e-2)" "unprognostic (1.96e-2)" 38.1 56.0 40.8 5.0 43.3 7.6 24.1 40.6 49.5 15.7 29.8 10.2 7.3 9.9 3.4 5.5 36.0 9.3 19.8 39.2 33.5 25.4 52.8 15.1 3.1 49.9 45.8 25.4 71.6 16.1 21.6 3.0 46.5 12.4 4.9 10.5 37.6 2.7 20.6 10.7 13.5 4.0 42.2 9.1 27.2 5.5 47.9 1.4 67.1 9.6 2.2 11.2 8.0 42.1 23.2 31.6 11.3 34.3 11.9 12.3 2.9 40.4 6.2 12.9 8.4 23.1 47.9 2.6 49.3 63.3 58.3 5.8 21.8 14.1 11.8 8.3 21.0 0.3 41.2 61.5 24.0 13.7 5.6 25.7 11.7 22.4 9.5 48.4 12.5 9.3 25.3 8.9 7.9 30.8 16.0 37.7 14.2 39.7 83.8 24.7 16.3 16.7 22.6 3.6 1.2 2.2 38.1 0.8 15.2 13.4 22.5 11.9 26.1 68.8 27.2 35.2 99.8 8.9 12.9 3.8 18.1 15.6 22.8 0.6 0.0 0.0 0.2 1.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.1 40.8 43.3 40.6 49.5 39.2 33.5 49.9 45.8 46.5 42.2 47.9 42.1 3.8 3.2 4.1 34.0 2.8 6.5 3.7 5.4 2.2 5.4 13.2 6.1 8.5 11.5 6.9 7.3 0.0 1.6 4.1 4.4 0.0 9.6 0.2 6.0 4.2 2.6 1.8 4.8 3.2 10.2 26.6 5.1 6.6 13.5 1.3 30.9 5.3 37.5 3.2 0.0 2.8 11.0 0.0 1.6 2.5 1.2 4.4 3.4 7.2 1.9 1.3 94.0 1.0 5.0 5.4 19.9 2.7 3.4 2.2 11.4 2.9 7.6 7.0 5.6 0.0 3.3 5.1 0.4 4.2 1.2 4.7 1.5 4.2 17.5 3.6 8.8 FIG4 "ALS11, CMT4J, dJ249I4.1, hSac3, KIAA0274, SAC3" ENSG00000112367 "FIG4 phosphoinositide 5-phosphatase" Q92562 6 109690609-109878098 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 49.5;Oligodendrocyte precursor cells: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017823, HPA068859" Approved Supported "Vesicles,Lipid droplets" NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Lipid droplets" "CAB017823: , HPA068859: AB_2686049" "prognostic unfavorable (5.91e-4)" "unprognostic (4.12e-2)" "prognostic favorable (8.42e-4)" "unprognostic (3.17e-2)" "unprognostic (1.66e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.73e-4)" "unprognostic (7.06e-2)" "unprognostic (2.69e-1)" "unprognostic (8.67e-2)" "unprognostic (3.44e-3)" "unprognostic (4.22e-2)" "prognostic favorable (8.19e-4)" "unprognostic (1.48e-1)" "unprognostic (2.02e-1)" "unprognostic (5.45e-2)" "unprognostic (2.00e-2)" 9.3 10.2 5.5 7.1 7.2 5.6 8.1 5.9 7.7 8.2 12.9 10.1 5.0 8.5 7.8 9.4 7.2 7.6 7.7 6.0 8.8 9.5 6.1 13.4 10.1 6.4 7.3 8.2 7.5 17.4 11.9 8.8 8.9 7.7 9.5 10.8 10.7 7.8 10.6 7.6 9.1 10.3 5.6 13.8 8.7 8.2 6.1 12.3 9.3 8.3 10.1 9.2 8.4 7.0 8.3 8.4 11.7 14.9 11.8 17.2 7.8 9.9 14.1 8.3 23.2 4.6 7.2 23.2 5.8 18.9 14.9 5.2 12.6 8.5 20.7 13.3 16.5 10.9 5.9 5.5 11.4 9.5 10.0 8.8 9.9 12.8 10.6 22.8 18.3 13.9 6.8 8.8 12.7 6.8 12.0 8.4 5.9 12.0 4.7 7.9 6.1 7.3 13.3 18.4 12.8 11.7 7.1 10.7 21.1 15.6 6.0 23.1 11.2 4.2 3.8 5.4 9.5 3.4 2.6 7.9 27.3 8.5 4.6 15.4 24.9 14.2 8.8 24.5 7.7 18.9 6.3 8.5 19.2 21.2 7.5 7.5 7.4 10.0 15.2 8.1 9.4 11.7 5.5 7.2 5.9 7.7 6.0 8.8 6.4 7.3 8.9 5.6 6.1 7.0 4.9 16.0 9.0 24.5 15.7 4.6 7.1 7.3 5.2 8.8 5.4 3.3 6.7 2.8 6.9 9.2 2.1 13.4 9.5 7.0 5.9 9.8 18.0 7.5 5.3 5.2 10.2 3.0 49.5 11.4 7.0 6.0 8.2 7.9 8.8 8.6 7.1 4.1 23.3 1.7 32.4 8.6 8.2 19.2 6.8 17.7 3.4 17.3 8.8 29.0 16.4 8.5 11.3 46.8 37.4 7.6 6.3 6.8 6.5 4.0 6.3 8.2 9.1 7.6 0.0 5.1 6.6 5.5 12.1 8.3 4.4 12.3 9.3 5.6 6.4 8.9 FLOT1 ENSG00000137312 "Flotillin 1" O75955 6 30727709-30742732 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 314.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 423.3;hTERT-RPE1: 242.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001393, CAB007766" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA 160000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "Vesicles, Plasma membrane" "CAB007766: AB_562116, HPA001393: AB_1078892" "unprognostic (2.68e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (5.78e-4)" "unprognostic (1.78e-2)" "unprognostic (2.21e-1)" "unprognostic (3.41e-3)" "unprognostic (2.68e-3)" "unprognostic (1.86e-1)" "unprognostic (2.65e-1)" "prognostic favorable (3.06e-4)" "unprognostic (1.81e-2)" "unprognostic (9.36e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (6.43e-3)" "unprognostic (3.92e-1)" "unprognostic (1.61e-2)" "unprognostic (2.46e-2)" 141.7 239.5 49.3 27.9 54.6 41.7 129.8 49.4 60.9 111.1 56.8 150.3 28.7 108.9 8.4 81.8 95.8 23.1 234.5 55.1 57.9 146.1 127.3 136.8 22.1 50.9 51.5 84.1 88.5 41.4 102.5 35.0 57.4 109.6 17.7 6.3 99.1 45.8 190.0 51.7 87.1 33.0 45.8 129.6 96.9 65.0 53.6 24.9 111.7 83.1 17.0 134.5 96.9 48.8 54.3 18.3 46.4 62.0 49.1 71.0 1.3 59.7 67.5 82.8 79.3 19.4 30.0 13.0 29.0 101.3 423.3 41.8 35.0 20.1 28.6 36.1 1.3 41.1 17.5 19.1 119.2 12.2 67.0 75.4 30.6 40.9 71.3 242.7 65.9 37.9 21.7 52.7 77.9 22.9 38.0 14.5 15.1 29.4 15.7 20.2 48.4 38.0 30.3 13.0 16.4 17.2 33.7 28.7 164.6 30.4 43.8 10.1 44.0 199.5 37.6 20.6 120.6 18.6 19.7 28.8 26.2 42.6 122.7 179.3 76.9 132.0 35.0 38.9 24.1 28.0 21.3 30.4 58.9 23.0 23.7 27.4 314.3 79.9 26.3 59.2 3.9 58.3 49.3 54.6 49.4 60.9 55.1 57.9 50.9 51.5 57.4 45.8 53.6 48.8 175.4 89.8 77.0 26.1 38.1 28.7 111.5 44.9 80.2 14.7 72.1 73.4 90.6 62.9 59.2 84.6 6.2 82.2 57.7 103.2 123.3 77.6 60.2 73.9 50.1 141.6 68.8 41.7 41.3 85.9 70.7 67.6 55.5 75.2 143.3 41.4 154.9 59.7 130.6 20.2 40.2 66.6 57.0 61.3 84.9 144.1 61.8 89.4 71.2 28.1 99.2 64.7 68.0 27.2 22.7 65.7 112.0 38.0 60.4 69.5 89.0 172.1 80.7 18.1 52.6 58.1 65.9 80.2 26.7 63.7 26.9 61.6 51.2 29.1 83.2 99.4 FLOT2 "ECS-1, ECS1, ESA, ESA1, M17S1" ENSG00000132589 "Flotillin 2" Q14254 17 28879335-28897733 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001396, CAB004395, HPA071038" Supported Supported "Vesicles,Plasma membrane" NA NA 170000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" Vesicles "CAB004395: AB_627618, HPA001396: AB_1078894, HPA071038: " "unprognostic (6.04e-2)" "unprognostic (8.76e-3)" "unprognostic (3.01e-1)" "unprognostic (8.92e-2)" "unprognostic (4.15e-3)" "unprognostic (2.17e-2)" "unprognostic (4.36e-3)" "unprognostic (2.12e-1)" "unprognostic (5.21e-2)" "unprognostic (1.20e-1)" "unprognostic (9.98e-2)" "unprognostic (2.80e-1)" "unprognostic (4.12e-3)" "unprognostic (2.64e-2)" "unprognostic (1.09e-1)" "unprognostic (1.11e-3)" "unprognostic (2.20e-2)" 60.2 46.4 38.4 56.8 38.6 97.1 56.2 28.1 47.6 42.8 45.2 58.9 21.0 39.1 21.2 69.3 46.8 27.0 63.5 41.1 42.5 71.4 98.4 59.5 68.2 45.9 37.1 37.7 38.8 30.0 22.3 58.4 41.3 67.8 27.2 20.3 61.7 51.6 51.6 38.2 53.0 35.3 37.5 122.7 44.6 10.4 47.1 47.8 39.6 44.1 63.6 78.8 49.6 36.1 55.5 90.8 69.6 60.2 33.6 44.2 76.6 42.5 57.9 60.9 71.3 96.0 45.7 76.9 79.3 47.6 42.0 63.3 76.5 69.7 25.9 245.5 91.4 92.7 80.5 70.3 43.6 76.8 15.2 53.3 53.6 49.3 66.9 64.1 97.4 21.8 89.0 65.6 28.9 83.5 21.2 54.0 61.4 48.6 24.6 32.6 70.6 189.3 92.0 166.9 61.9 103.3 99.8 69.6 77.5 66.7 72.3 136.3 81.5 21.4 38.2 35.2 65.0 36.5 68.2 39.5 59.9 72.3 40.7 171.9 106.0 213.2 98.8 96.6 72.6 98.5 74.6 84.5 144.3 118.1 55.3 69.0 415.2 78.5 110.2 38.8 97.6 143.2 38.4 38.6 28.1 47.6 41.1 42.5 45.9 37.1 41.3 37.5 47.1 36.1 34.2 22.4 21.9 12.7 46.8 12.6 27.1 20.6 29.6 6.9 24.9 30.1 32.9 22.8 16.5 20.2 10.4 96.6 20.5 29.0 15.6 39.3 13.0 25.8 13.2 37.0 25.8 49.2 17.0 31.1 68.9 14.8 23.0 27.6 6.3 15.6 48.9 45.1 44.4 5.0 19.2 25.9 10.2 43.3 22.6 42.3 10.8 31.1 8.8 22.5 75.2 10.7 35.0 16.1 11.0 32.2 16.5 8.6 27.8 14.8 14.8 26.7 19.1 12.4 19.7 7.1 13.4 1.6 6.9 42.4 9.2 37.1 32.5 4.2 32.0 26.7 FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 181.7;Distal enterocytes: 226.6;Paneth cells: 221.0;Proximal enterocytes: 210.9;Syncytiotrophoblasts: 200.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 165.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 60000000 "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA046542: AB_2679691, HPA056371: AB_2683108" "unprognostic (6.94e-3)" "unprognostic (6.53e-2)" "unprognostic (2.68e-3)" "prognostic favorable (2.45e-4)" "unprognostic (5.64e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (4.99e-1)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (4.23e-2)" "prognostic favorable (5.70e-13)" "unprognostic (3.75e-2)" "unprognostic (4.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.13e-3)" 34.2 34.4 8.3 49.8 8.2 7.7 26.3 8.3 11.2 54.5 23.8 124.2 90.3 20.7 113.0 17.0 51.1 46.6 20.6 8.3 10.5 78.2 104.8 55.1 168.2 9.5 8.8 23.8 23.9 56.9 17.6 72.6 9.6 50.2 140.7 5.7 40.8 60.4 15.8 14.9 81.3 26.7 9.3 71.8 63.9 27.7 10.8 26.8 70.6 17.7 94.1 74.9 13.2 12.8 15.9 10.6 2.2 31.9 4.2 0.3 11.0 16.6 34.4 17.1 31.6 14.5 165.1 23.9 40.9 21.3 18.8 9.4 15.3 35.4 22.4 16.9 25.6 19.7 9.2 32.7 14.2 2.0 62.7 15.3 19.7 6.2 8.1 55.2 6.9 13.3 9.3 0.5 20.6 17.5 5.0 17.7 5.4 48.1 16.9 26.9 0.2 26.2 63.5 40.5 10.9 10.6 47.9 18.5 26.2 17.9 13.6 7.8 1.8 5.8 9.0 38.9 5.6 28.5 31.0 8.5 14.5 58.9 9.5 54.8 100.4 51.9 27.2 99.9 23.1 23.8 19.5 22.9 44.0 14.1 18.9 22.0 12.8 44.6 91.1 25.4 21.4 64.8 8.3 8.2 8.3 11.2 8.3 10.5 9.5 8.8 9.6 9.3 10.8 12.8 12.9 25.6 28.6 4.2 10.5 3.6 27.4 99.3 6.8 4.4 22.2 10.4 5.6 40.0 77.8 84.6 0.0 181.7 13.9 226.6 15.6 64.1 61.0 31.5 2.8 11.6 10.8 20.6 5.8 50.3 24.2 16.7 33.1 13.3 8.2 11.1 25.7 42.7 156.4 0.0 6.3 44.4 44.7 121.0 13.5 24.4 23.3 85.4 8.8 2.8 29.6 13.0 10.3 4.0 4.7 34.9 221.0 19.5 8.7 23.6 210.9 40.2 53.7 5.0 6.6 16.7 13.2 109.0 24.8 8.5 2.8 200.6 11.2 34.6 79.5 40.3 FZD7 FzE3 ENSG00000155760 "Frizzled class receptor 7" O75084 2 202033855-202038441 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 30.9;Breast myoepithelial cells: 37.0;Cardiomyocytes: 21.1;Fibroblasts: 23.5;Proximal enterocytes: 21.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 30.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 42.8;BJ hTERT+: 48.4;CAPAN-2: 62.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059979, HPA069165, HPA076183" Approved Supported Vesicles NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA059979: , HPA069165: AB_2686096, HPA076183: " "unprognostic (3.44e-2)" "unprognostic (6.89e-2)" "unprognostic (9.30e-3)" "unprognostic (2.44e-3)" "unprognostic (4.92e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.71e-5)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-3)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (4.16e-2)" "unprognostic (2.05e-3)" 10.2 3.0 4.9 5.6 4.7 0.4 15.5 30.2 4.3 13.2 6.3 36.7 6.9 18.4 14.1 9.4 16.8 6.3 14.4 8.8 5.0 8.2 1.2 5.3 3.9 5.2 4.9 25.0 1.7 1.1 9.3 5.7 5.5 19.2 5.5 1.3 21.7 23.5 26.7 10.9 10.8 11.1 4.9 1.9 5.9 2.1 4.5 1.1 5.1 9.5 3.8 27.1 15.3 5.6 10.3 5.2 33.2 10.8 10.6 7.9 14.8 42.8 48.4 11.9 13.9 32.2 62.7 0.1 25.1 26.2 7.9 10.6 6.0 1.3 13.7 5.4 8.6 1.1 2.1 2.7 7.2 2.1 2.1 7.6 1.0 6.4 3.7 9.5 0.0 0.7 2.9 2.6 9.8 4.2 0.0 5.7 36.6 2.0 3.5 4.2 6.4 1.1 1.9 6.1 5.5 12.6 5.4 0.4 6.8 26.7 3.8 2.5 0.1 23.8 8.8 15.0 5.4 2.7 2.2 0.1 4.9 0.5 16.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.7 30.2 4.3 8.8 5.0 5.2 4.9 5.5 4.9 4.5 5.6 3.5 0.0 8.1 3.6 2.0 10.3 8.3 1.9 14.8 0.0 30.9 37.0 21.1 1.5 0.3 1.8 0.0 0.5 2.0 4.7 1.9 1.6 0.1 1.5 2.0 1.7 1.2 0.0 1.5 0.2 1.1 23.5 2.6 3.6 1.3 7.5 0.7 0.7 1.5 0.0 0.2 9.9 0.0 0.8 5.7 0.5 5.3 2.0 3.6 0.0 0.1 7.5 0.0 0.0 0.1 0.6 2.1 4.9 1.7 6.9 21.3 0.1 0.9 0.6 6.6 13.5 16.3 1.6 2.9 11.4 9.8 0.8 2.5 0.5 7.6 1.8 GAL "GAL-GMAP, GALN, GLNN, GMAP" ENSG00000069482 "Galanin and GMAP prepropeptide" P22466 11 68683779-68691175 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hormone, Neuropeptide" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 23 "brain: 645.9;pituitary gland: 885.8" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 22.2;Ductal cells: 38.9;Endometrial ciliated cells: 64.2;Endometrial stromal cells: 50.8;Exocrine glandular cells: 52.1;Extravillous trophoblasts: 48.7;Glandular and luminal cells: 26.4;Pancreatic endocrine cells: 39.5;Prostatic glandular cells: 82.5;Urothelial cells: 24.3" "Cancer enhanced" "Detected in many" "testis cancer: 22.2" "Region enriched" "Detected in many" 13 "hypothalamus: 645.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 267.2;HEK 293: 119.3;K-562: 139.5;NB-4: 493.5;SH-SY5Y: 189.6" "Region enhanced" "Detected in many" "hypothalamus: 82.6" "Low region specificity" "Detected in all" "HPA049864, CAB079779" Enhanced Supported Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 60000 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 24: NB-4 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" Vesicles "CAB079779: , HPA049864: AB_2680922" "unprognostic (8.56e-2)" "unprognostic (1.45e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (8.07e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (5.98e-2)" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (7.42e-2)" "unprognostic (1.20e-1)" "unprognostic (8.85e-2)" "unprognostic (7.88e-2)" "unprognostic (5.38e-2)" "unprognostic (3.24e-2)" 3.2 0.9 2.8 14.9 2.1 0.7 4.4 1.1 5.2 1.0 0.8 17.6 1.8 0.2 0.0 0.8 1.0 0.2 1.0 2.2 645.9 1.5 0.3 0.5 0.1 48.5 5.1 0.2 2.1 0.1 885.8 0.3 13.8 4.4 4.0 0.0 0.9 0.2 0.4 33.3 4.1 9.9 0.6 0.3 9.7 1.0 19.5 0.7 0.4 0.0 0.0 0.7 2.9 2.6 0.0 11.0 1.1 0.3 0.0 0.0 24.0 36.7 0.0 0.7 0.0 267.2 9.9 0.0 12.7 1.3 0.4 0.1 0.0 0.2 0.0 0.0 119.3 6.4 74.6 0.0 1.3 3.7 0.0 1.7 4.0 0.0 0.1 0.0 6.3 0.0 139.5 0.0 0.2 77.2 0.0 493.5 60.3 2.9 23.7 0.0 0.1 51.1 0.6 0.0 49.8 189.6 25.8 1.5 0.0 26.8 1.5 57.6 0.0 0.0 0.0 0.3 2.9 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.1 1.1 5.2 2.2 645.9 48.5 5.1 13.8 0.6 19.5 2.6 0.6 0.0 0.0 0.0 0.2 2.0 22.2 0.1 0.0 0.0 3.2 5.8 1.4 0.0 0.0 0.0 0.0 0.6 0.1 0.7 0.0 38.9 0.1 64.2 50.8 3.4 1.8 4.2 2.1 52.1 48.7 6.6 2.0 26.4 4.5 0.4 0.0 0.0 2.0 0.0 0.2 1.1 4.1 0.0 1.2 0.2 0.0 0.7 1.8 0.0 0.6 0.0 0.0 0.0 0.3 39.5 0.1 0.0 1.0 82.5 0.0 0.4 0.0 0.0 0.0 1.6 6.7 2.2 10.9 1.1 3.4 1.9 0.8 0.0 1.3 24.3 GASK1A "C3orf41, DKFZP434B172, FAM198A" ENSG00000144649 "Golgi associated kinase 1A" Q9UFP1 3 42979267-43060211 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.4;Extravillous trophoblasts: 2.6;Fibroblasts: 1.8;Hofbauer cells: 3.9;Syncytiotrophoblasts: 2.7" "Cancer enhanced" "Detected in many" "glioma: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 3.1;RPMI-8226: 3.4;SK-BR-3: 2.6;T-47d: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047726 Approved Supported Vesicles "Secreted - unknown location" NA NA 600000 "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA047726: AB_10960554" "unprognostic (2.16e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (2.93e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.65e-2)" "unprognostic (5.79e-2)" "unprognostic (2.69e-1)" "unprognostic (6.21e-2)" "unprognostic (2.02e-1)" "unprognostic (1.50e-1)" "unprognostic (1.57e-4)" "unprognostic (4.45e-2)" "unprognostic (2.09e-2)" "unprognostic (3.49e-2)" "unprognostic (3.81e-1)" 5.5 2.1 4.9 2.5 6.4 0.0 4.2 6.3 3.8 10.6 4.9 3.4 0.7 9.8 2.2 1.8 11.3 5.3 1.7 4.1 5.9 1.0 13.1 3.1 0.7 8.8 7.7 6.8 2.0 0.1 3.0 2.0 7.6 2.6 1.0 3.9 2.6 2.2 1.4 1.7 2.1 6.0 6.3 0.9 3.4 2.9 10.0 0.6 2.1 0.8 0.3 3.2 3.9 5.2 0.0 0.0 0.0 3.1 0.1 0.0 1.1 0.2 0.3 0.0 0.0 0.1 0.9 0.0 1.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 1.9 0.7 0.0 0.0 0.6 0.4 1.2 0.8 0.0 0.4 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.8 0.0 1.9 0.0 0.0 0.0 0.0 3.4 0.0 0.5 0.1 0.3 0.0 2.6 0.0 0.1 6.7 0.9 0.0 0.4 0.6 1.4 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.9 6.4 6.3 3.8 4.1 5.9 8.8 7.7 7.6 6.3 10.0 5.2 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Distal tubular cells: 1.9;Excitatory neurons: 1.6;Fibroblasts: 3.1;Oligodendrocyte precursor cells: 7.1;Spermatogonia: 2.4" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 20.4;LHCN-M2: 33.1;SuSa: 15.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.2" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" 1.3 0.1 0.3 0.9 0.3 0.0 0.4 0.4 0.8 0.2 0.0 0.7 0.3 1.4 0.4 0.4 0.5 2.4 2.8 0.3 0.4 0.2 0.4 0.2 0.1 0.8 0.4 0.1 0.7 0.1 0.1 10.9 1.0 0.3 0.3 0.0 0.0 1.4 0.0 0.0 0.9 1.1 0.4 0.0 0.6 0.6 0.8 0.1 0.6 0.0 0.0 0.8 0.9 0.4 0.0 0.0 0.2 0.0 1.1 0.6 3.9 2.6 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 3.2 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 3.0 0.0 20.4 0.2 0.0 0.0 0.0 33.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.4 0.8 0.3 0.4 0.8 0.4 1.0 0.4 0.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.8 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.0 2.4 0.0 0.0 0.3 0.1 0.0 0.0 0.1 GGA1 ENSG00000100083 "Golgi associated, gamma adaptin ear containing, ARF binding protein 1" Q9UJY5 22 37608725-37633564 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 179.3" "Cell type enhanced" "Detected in all" "Late spermatids: 221.2;Spermatocytes: 193.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048280, HPA051016" Supported Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus, Vesicles" Nucleoplasm "HPA048280: AB_2680338, HPA051016: AB_2681312" "unprognostic (1.64e-1)" "unprognostic (1.42e-2)" "unprognostic (4.08e-1)" "unprognostic (9.23e-3)" "unprognostic (2.00e-1)" "unprognostic (2.77e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (2.32e-2)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "prognostic favorable (4.86e-4)" "unprognostic (1.42e-2)" "unprognostic (1.53e-2)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (2.22e-1)" "unprognostic (1.16e-3)" 25.0 49.3 35.9 23.3 39.7 37.2 27.3 39.0 42.3 38.0 41.0 35.0 24.3 32.1 21.5 41.1 37.4 20.4 29.5 35.3 35.0 42.4 42.1 33.7 29.1 41.1 37.6 46.3 34.5 33.2 52.7 19.1 38.4 40.0 17.8 22.8 34.9 19.6 43.1 35.7 40.7 16.9 36.1 55.6 34.9 179.3 41.2 26.9 44.7 24.6 21.1 31.6 33.5 45.0 37.4 28.3 32.9 31.1 28.0 23.0 35.4 30.8 25.0 27.0 29.6 23.3 21.8 59.9 20.6 22.9 17.0 35.0 29.4 35.6 24.8 51.0 53.6 24.0 52.3 27.3 28.1 56.1 42.6 28.4 31.3 38.9 24.2 45.1 26.5 30.3 48.0 36.8 27.8 37.7 24.8 64.2 26.2 39.2 28.7 28.5 25.8 25.2 28.8 31.0 30.4 54.0 18.7 39.0 48.9 31.3 42.4 42.0 31.0 36.8 35.2 32.1 24.4 81.1 35.3 62.5 39.9 33.6 30.8 8.1 10.7 6.1 18.0 10.2 22.1 8.3 7.2 23.3 6.7 5.0 5.1 16.5 4.5 11.6 7.9 5.8 8.0 11.5 35.9 39.7 39.0 42.3 35.3 35.0 41.1 37.6 38.4 36.1 41.2 45.0 17.9 25.6 38.5 26.8 50.9 24.2 31.1 36.5 21.1 57.6 26.5 20.8 19.2 20.0 34.5 44.1 83.4 38.8 34.7 67.3 5.9 34.9 148.2 27.6 19.8 32.6 32.4 38.3 18.4 20.1 37.4 18.8 44.4 26.5 49.4 33.3 40.7 20.4 77.1 25.2 19.3 40.4 32.6 66.9 40.3 221.2 26.4 50.5 16.0 20.6 47.9 37.0 73.2 16.6 28.7 36.6 51.6 22.6 24.4 24.7 55.4 13.2 46.7 74.1 26.3 26.9 22.1 193.4 50.4 19.7 28.6 56.8 59.6 44.4 42.8 33.6 GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996609-33097202 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 857.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: AB_2677039, HPA069503: AB_2686142" "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favorable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" 22.0 36.1 12.1 27.8 13.0 21.9 20.5 12.5 14.8 33.4 16.0 43.5 43.0 21.9 103.6 15.4 28.2 32.0 15.5 12.5 14.8 46.0 48.2 42.7 25.8 14.3 12.9 21.4 30.8 59.4 18.5 53.8 15.4 23.2 45.6 14.9 25.3 29.3 7.7 15.8 31.0 30.6 12.4 24.4 35.5 13.5 13.5 17.5 52.8 10.8 23.0 31.8 16.2 15.1 37.4 63.6 39.8 48.3 241.9 123.7 857.2 59.1 157.6 73.7 95.1 91.3 86.5 17.9 50.9 120.9 53.9 35.1 38.1 75.5 53.7 104.9 33.0 69.9 35.3 47.4 124.3 50.5 69.9 144.9 70.2 67.0 39.2 144.1 116.5 24.7 64.3 67.0 81.8 44.6 29.6 31.6 26.4 78.0 27.0 24.7 26.4 86.6 78.4 54.4 12.0 40.3 75.0 120.2 74.4 69.3 80.3 130.2 67.7 46.8 32.2 65.2 50.1 53.2 87.9 5.9 99.6 71.2 36.7 43.9 146.2 86.4 29.2 125.8 40.4 37.9 34.3 31.8 166.5 35.6 17.9 21.8 56.6 26.0 92.1 35.1 77.1 91.9 12.1 13.0 12.5 14.8 12.5 14.8 14.3 12.9 15.4 12.4 13.5 15.1 8.7 19.2 25.3 39.2 18.6 6.0 13.6 60.1 10.8 11.3 11.5 7.5 9.1 34.3 43.3 27.6 6.2 100.1 14.1 41.9 27.4 53.5 24.8 18.7 16.0 17.4 16.9 20.6 46.7 35.4 55.3 29.2 26.0 27.1 26.6 20.6 19.6 39.7 79.5 5.0 46.0 23.5 40.7 43.9 13.9 5.0 15.2 41.7 14.2 23.4 64.6 16.5 10.3 27.2 24.2 28.1 43.4 21.1 19.8 9.9 36.2 33.1 31.0 16.2 13.1 12.9 16.3 1.0 6.6 10.1 3.4 49.1 18.7 51.0 32.0 12.1 GM2A SAP-3 ENSG00000196743 "GM2 ganglioside activator" P17900 5 151212150-151270440 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Gangliosidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 224.7;Hofbauer cells: 100.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 30.9;dendritic cells: 39.6;monocytes: 40.4" "Cell line enhanced" "Detected in all" "BEWO: 207.1;HBEC3-KT: 291.8;hTCEpi: 287.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008063 Enhanced Approved Vesicles,Cytosol "Intracellular and membrane" NA NA 19000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Vesicles, Cytosol" "HPA008063: AB_1849842" "unprognostic (4.33e-2)" "unprognostic (8.97e-3)" "unprognostic (2.27e-1)" "unprognostic (3.01e-1)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (1.77e-5)" "unprognostic (1.22e-1)" "unprognostic (1.72e-2)" "unprognostic (1.31e-2)" "unprognostic (1.50e-2)" "unprognostic (5.33e-3)" "unprognostic (9.81e-2)" "unprognostic (4.24e-2)" "unprognostic (4.42e-2)" "unprognostic (3.02e-2)" "unprognostic (1.65e-1)" 17.4 20.5 29.3 30.0 39.7 20.6 28.0 38.9 31.1 30.8 17.9 19.7 15.8 15.1 30.8 56.2 15.4 23.4 26.2 27.1 34.3 11.4 24.8 39.0 61.4 42.6 37.9 21.3 14.9 28.3 6.6 57.9 44.3 21.1 26.3 11.7 17.0 17.9 7.2 81.8 16.3 20.0 39.0 36.0 15.8 11.6 36.2 72.3 13.0 10.5 77.9 40.3 49.5 46.7 22.3 14.8 15.1 71.7 98.0 48.2 207.1 35.0 75.1 19.0 25.6 30.3 26.1 71.9 35.1 26.9 51.1 60.0 16.7 291.8 27.2 41.4 10.5 11.7 16.8 37.9 23.7 19.1 117.1 65.4 287.0 24.4 16.4 26.0 27.6 85.1 11.4 30.7 30.1 9.6 38.4 18.0 10.2 11.4 32.3 17.7 7.1 46.3 18.4 43.3 3.9 13.4 29.1 133.0 58.3 52.0 30.7 22.5 24.6 46.0 17.6 38.3 10.6 75.2 96.8 187.0 53.1 30.1 19.4 7.6 40.4 2.4 3.7 13.6 2.7 30.9 4.3 3.9 39.6 29.8 6.1 4.8 8.7 4.4 3.4 28.0 5.4 18.6 29.3 39.7 38.9 31.1 27.1 34.3 42.6 37.9 44.3 39.0 36.2 46.7 5.8 16.0 23.0 5.5 25.0 14.9 18.5 63.2 26.7 5.8 5.4 15.5 30.9 0.0 29.7 18.4 2.1 53.6 8.3 4.4 1.9 7.2 0.5 5.7 6.8 7.3 3.6 5.0 2.2 8.1 224.7 10.2 10.7 7.7 69.6 16.3 8.6 24.2 100.8 6.7 2.7 5.4 10.2 55.7 32.5 1.6 8.1 67.8 8.8 2.8 52.5 8.0 7.2 3.5 9.5 6.0 4.7 13.9 28.8 6.7 6.2 5.4 19.9 3.7 0.0 7.9 6.9 1.8 4.2 45.6 23.9 52.5 5.6 6.4 6.7 36.5 GNL1 HSR1 ENSG00000204590 "G protein nucleolar 1 (putative)" P36915 6 30541377-30557174 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 193.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033575, HPA043338, HPA050455" Uncertain Supported Vesicles NA NA 11000 "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB033575: AB_2109945, HPA043338: AB_2678437, HPA050455: AB_2681132" "unprognostic (2.76e-2)" "unprognostic (3.68e-2)" "unprognostic (2.21e-1)" "unprognostic (3.53e-2)" "unprognostic (3.30e-2)" "unprognostic (2.75e-1)" "unprognostic (4.22e-2)" "unprognostic (8.33e-2)" "unprognostic (1.03e-1)" "unprognostic (3.84e-2)" "unprognostic (3.95e-3)" "unprognostic (7.32e-2)" "unprognostic (5.67e-3)" "unprognostic (4.42e-2)" "unprognostic (2.10e-1)" "unprognostic (4.15e-1)" "unprognostic (1.78e-1)" 22.6 19.6 3.3 3.5 3.5 2.0 21.7 2.0 4.0 30.5 1.7 19.3 0.6 27.3 3.9 17.0 26.2 2.4 15.2 2.3 4.8 21.2 13.1 27.8 2.3 3.3 3.0 37.5 24.3 7.8 23.8 2.8 3.5 19.9 3.4 4.1 16.6 3.9 15.0 23.3 17.4 4.5 2.7 18.7 20.0 38.0 4.7 5.0 23.3 1.6 4.6 21.1 22.9 5.4 10.5 2.2 5.9 16.9 10.9 12.8 0.4 3.2 6.4 2.6 4.0 15.1 6.5 4.8 6.2 10.4 25.8 6.9 15.4 12.7 4.4 1.8 9.0 7.8 7.9 1.4 0.0 1.3 5.0 11.0 9.9 20.4 6.7 0.0 1.1 18.6 14.2 0.3 6.5 2.4 3.8 0.2 3.4 8.4 1.6 7.3 3.6 5.3 8.7 4.5 5.2 4.9 4.2 3.1 1.6 2.0 3.0 4.9 6.2 10.5 3.0 2.0 3.7 7.9 9.3 9.9 0.1 6.6 13.1 0.2 0.2 0.2 0.7 0.2 1.0 0.4 0.8 0.9 0.0 0.3 0.1 0.3 0.2 0.4 0.2 0.1 0.5 0.5 3.3 3.5 2.0 4.0 2.3 4.8 3.3 3.0 3.5 2.7 4.7 5.4 48.2 44.8 41.8 17.3 45.0 59.3 104.0 44.1 56.3 40.6 35.4 40.6 14.3 34.3 28.8 25.8 41.7 72.6 36.3 22.6 23.5 38.4 113.1 30.0 40.2 50.8 46.0 13.3 26.2 35.3 65.5 46.4 27.5 47.5 31.7 40.9 50.7 16.9 28.5 16.8 27.0 25.8 26.4 19.8 32.5 193.5 36.4 24.6 28.4 9.4 14.8 30.9 18.6 11.1 10.8 29.9 22.1 32.0 42.6 56.2 32.4 30.3 20.7 34.6 39.5 47.9 58.1 108.4 51.8 36.1 40.6 160.1 46.0 40.9 27.0 66.7 GOLPH3 "GOPP1, GPP34, MIDAS, Vps74" ENSG00000113384 "Golgi phosphoprotein 3" Q9H4A6 5 32124716-32174319 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044564, HPA055841" Approved Supported "Golgi apparatus,Vesicles" NA NA 23000 "Cluster 26: Non-specific - Mitochondria" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus, Vesicles" "HPA044564: AB_10795169, HPA055841: AB_2682940" "unprognostic (1.64e-2)" "unprognostic (1.66e-1)" "unprognostic (9.27e-2)" "unprognostic (1.01e-1)" "unprognostic (2.28e-1)" "unprognostic (9.34e-2)" "unprognostic (1.89e-2)" "unprognostic (8.19e-2)" "unprognostic (2.95e-2)" "unprognostic (7.48e-2)" "unprognostic (2.02e-1)" "unprognostic (1.96e-1)" "unprognostic (1.58e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (1.11e-1)" "unprognostic (1.52e-2)" 50.1 38.3 28.5 41.9 29.2 20.8 50.0 29.8 34.5 56.2 32.9 76.6 46.3 41.6 58.7 43.1 41.0 77.7 38.4 26.5 29.6 61.5 110.1 50.7 49.2 30.2 29.5 51.5 62.6 54.9 29.8 68.4 29.9 75.3 60.2 19.8 64.8 50.4 37.3 32.8 49.3 52.3 29.1 39.5 52.9 27.0 29.7 43.9 48.0 57.0 52.4 60.5 41.3 32.3 57.7 37.9 59.9 65.5 111.3 106.1 171.6 77.8 103.3 71.5 67.7 51.9 101.3 51.7 75.0 105.7 69.3 52.8 75.1 54.9 89.7 67.7 44.9 56.9 119.9 99.4 89.4 88.8 64.0 81.3 77.1 70.3 80.1 65.8 57.9 33.6 60.5 121.8 80.4 58.0 57.1 115.3 51.8 78.0 38.5 52.8 86.4 53.8 89.9 72.1 45.6 51.0 180.8 186.9 79.4 75.6 76.4 97.1 56.5 62.7 58.5 49.7 55.6 136.1 179.3 62.5 56.3 125.8 76.4 6.8 8.0 19.2 7.8 10.6 6.8 11.5 8.4 10.1 8.9 16.0 9.9 7.2 7.9 8.5 10.5 6.9 13.2 4.2 28.5 29.2 29.8 34.5 26.5 29.6 30.2 29.5 29.9 29.1 29.7 32.3 33.9 60.9 49.2 26.8 53.3 70.0 44.5 30.0 51.2 13.5 59.6 30.7 31.7 88.6 42.8 44.1 10.4 67.3 52.0 72.6 52.8 58.0 5.2 46.3 35.8 46.2 52.0 50.5 47.9 44.1 111.6 51.7 57.6 71.3 14.5 16.8 59.3 153.6 54.4 13.5 45.8 86.3 40.7 63.7 56.2 16.1 50.7 49.1 44.4 43.1 48.7 20.2 36.0 53.8 60.1 49.7 35.1 57.2 120.0 83.9 59.8 59.8 49.1 10.0 39.5 30.8 52.1 15.4 25.1 68.2 73.6 110.0 45.6 50.4 50.2 80.7 GOLT1B "CGI-141, GOT1, YMR292W" ENSG00000111711 "Golgi transport 1B" Q9Y3E0 12 21501781-21518408 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055909, HPA066383" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 5: NTERA-2 - Transcription" "Cluster 55: Plasma cells - Humoral immune response" Vesicles Nucleoplasm "HPA055909: AB_2682967, HPA066383: AB_2685667" "unprognostic (1.22e-2)" "unprognostic (3.07e-3)" "unprognostic (1.84e-1)" "unprognostic (3.65e-1)" "unprognostic (3.45e-1)" "unprognostic (5.37e-3)" "prognostic unfavorable (1.99e-8)" "unprognostic (2.24e-2)" "unprognostic (1.60e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.83e-10)" "unprognostic (3.13e-1)" "unprognostic (2.14e-1)" "unprognostic (6.78e-2)" "unprognostic (1.04e-1)" 17.5 22.1 12.7 16.9 14.1 25.8 18.5 13.4 18.9 18.0 12.7 13.4 10.6 14.6 15.6 13.6 12.5 13.9 14.8 13.9 15.1 15.5 18.8 17.6 15.0 13.2 14.6 10.9 21.6 11.9 19.0 29.0 13.8 16.1 14.8 14.1 16.1 13.2 15.5 12.9 11.3 17.7 13.9 12.4 14.2 10.6 14.7 11.2 15.9 11.8 14.1 17.8 12.2 16.3 31.2 30.0 28.5 36.5 56.5 83.2 46.1 126.5 48.2 40.4 63.3 45.4 48.1 19.4 29.8 66.6 71.0 30.1 23.4 27.2 69.5 29.4 22.8 29.7 19.6 32.8 61.0 37.0 36.8 44.2 50.1 44.9 85.6 67.7 35.8 24.4 18.6 21.1 59.2 30.7 17.3 62.1 75.7 27.8 23.5 14.0 65.0 39.4 32.2 18.7 7.2 23.1 49.0 20.6 70.4 90.2 28.2 39.4 40.6 46.5 49.5 57.1 67.2 20.3 45.9 51.8 63.6 35.5 64.2 48.0 26.6 20.8 22.1 31.4 26.6 22.7 25.8 24.4 27.0 25.9 23.3 23.8 7.2 21.6 29.4 29.4 28.0 27.6 12.7 14.1 13.4 18.9 13.9 15.1 13.2 14.6 13.8 13.9 14.7 16.3 23.4 9.6 15.6 15.0 38.9 46.7 23.4 42.7 27.3 27.6 20.4 11.2 18.9 22.8 36.8 16.5 10.4 29.0 34.9 13.8 27.4 31.6 3.4 10.9 26.3 28.7 13.1 22.9 70.4 33.4 72.4 45.7 15.3 21.7 21.5 10.3 16.8 23.2 41.0 18.5 49.3 31.7 38.7 23.6 65.1 5.2 17.4 35.4 53.4 14.0 26.0 17.5 18.6 25.1 25.4 38.6 15.4 19.9 75.8 49.0 8.7 21.7 18.2 7.7 13.1 24.6 39.3 23.7 32.4 22.8 63.9 64.0 39.1 9.6 14.6 44.9 GPRC5B RAIG-2 ENSG00000167191 "G protein-coupled receptor class C group 5 member B" Q9NZH0 16 19856691-19886167 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 490.3" "Cell type enhanced" "Detected in many" "Early spermatids: 197.7;Late spermatids: 269.9;Oligodendrocytes: 171.0" "Cancer enhanced" "Detected in all" "glioma: 52.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.8" "Lineage enhanced" "Detected in single" "T-cells: 2.8" "Cell line enhanced" "Detected in many" "EFO-21: 92.5;HHSteC: 60.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015247 Enhanced Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 34: Spermatids - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA015247: AB_1849323" "unprognostic (1.26e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.60e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (3.97e-2)" "unprognostic (5.70e-2)" "unprognostic (1.42e-1)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.30e-4)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (4.42e-3)" "unprognostic (6.78e-3)" 25.3 7.0 249.1 4.4 428.3 0.1 19.6 365.2 263.4 12.8 13.1 8.1 5.7 13.1 14.8 8.1 20.1 15.3 40.7 245.8 278.4 22.4 3.2 5.8 7.8 379.4 327.1 22.6 21.7 45.9 14.1 15.7 333.0 9.6 2.4 17.4 40.1 17.7 72.7 7.5 11.1 7.5 262.7 2.5 41.3 34.0 315.0 3.2 13.8 73.8 3.4 12.8 8.6 490.3 1.2 29.9 29.0 5.2 29.3 2.0 5.3 0.3 7.4 2.9 1.8 28.0 1.0 0.0 92.5 1.0 18.9 1.6 21.6 0.2 1.7 0.2 8.6 0.0 0.1 0.0 60.3 0.0 0.0 2.5 0.0 4.9 0.0 7.9 14.3 0.7 6.6 0.6 6.7 1.5 0.1 0.1 31.8 0.0 15.6 8.9 0.0 0.2 1.1 13.8 22.9 1.9 3.6 1.9 27.2 9.1 0.1 0.6 2.9 0.0 3.5 14.4 0.8 0.4 0.1 0.3 1.4 0.3 1.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.5 249.1 428.3 365.2 263.4 245.8 278.4 379.4 327.1 333.0 262.7 315.0 490.3 71.4 0.0 3.0 75.4 1.2 1.3 5.3 2.6 9.1 30.7 22.5 16.3 15.7 40.0 7.2 31.3 0.0 5.0 0.3 0.2 1.9 65.3 197.7 4.1 20.7 44.8 0.0 0.0 2.4 64.5 1.4 14.8 31.6 13.7 0.0 0.4 9.3 0.2 4.1 0.0 13.5 0.0 38.7 1.6 2.6 269.9 23.9 2.2 16.0 7.5 1.0 24.8 0.0 51.8 171.0 72.8 0.0 26.7 1.3 12.3 0.0 0.3 3.3 6.0 13.1 3.3 13.0 4.9 1.6 2.4 1.7 2.5 0.8 7.0 0.2 1.6 GRB10 ENSG00000106070 "Growth factor receptor bound protein 10" Q13322 7 50590063-50793462 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 143.0;Late spermatids: 212.6;Oligodendrocytes: 124.7;Rod photoreceptor cells: 81.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 10.0;eosinophil: 3.0" "Lineage enriched" "Detected in single" 28 "granulocytes: 10.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB019423, HPA027502, HPA031818" Enhanced Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 54: Non-specific - Microtubule organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "CAB019423: AB_2112883, HPA027502: AB_10602325, HPA031818: AB_2674057" "unprognostic (2.82e-2)" "unprognostic (1.69e-3)" "unprognostic (1.25e-2)" "unprognostic (1.45e-2)" "unprognostic (3.68e-2)" "unprognostic (1.60e-1)" "unprognostic (6.83e-2)" "unprognostic (5.91e-3)" "unprognostic (1.67e-2)" "unprognostic (2.31e-3)" "unprognostic (4.44e-1)" "unprognostic (2.07e-1)" "unprognostic (1.23e-3)" "unprognostic (1.73e-3)" "unprognostic (8.16e-3)" "unprognostic (2.63e-2)" "unprognostic (8.50e-2)" 27.6 26.0 29.5 6.5 33.6 10.0 25.0 25.2 32.5 18.2 28.5 27.2 17.2 19.8 10.3 9.5 18.8 21.6 34.8 26.5 40.2 29.3 32.1 20.6 6.0 31.5 41.8 14.2 94.3 10.5 24.3 14.7 40.2 20.1 6.4 83.5 16.5 15.0 57.4 9.1 13.3 16.1 21.6 36.8 17.6 18.1 48.2 2.8 27.8 76.0 4.0 31.0 15.9 33.5 0.3 32.5 51.6 21.1 23.5 17.8 27.6 13.1 11.3 24.9 29.7 19.8 0.4 0.7 22.6 16.7 71.0 3.1 53.5 13.9 12.2 0.4 21.6 56.7 32.6 14.4 49.8 36.0 84.1 46.4 21.0 38.6 37.4 23.9 62.7 3.9 109.5 0.6 18.7 4.0 6.4 48.0 56.9 27.2 55.4 16.8 0.0 0.3 16.0 13.1 22.7 0.2 1.6 8.1 68.7 33.0 27.7 71.6 78.7 21.8 29.6 45.4 50.4 2.1 0.7 0.4 68.9 32.2 75.2 10.0 0.1 3.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 29.5 33.6 25.2 32.5 26.5 40.2 31.5 41.8 40.2 21.6 48.2 33.5 46.3 6.4 8.3 3.9 1.2 7.5 5.3 9.4 7.4 12.1 14.8 9.0 13.5 47.1 5.2 5.5 87.6 4.5 0.3 6.9 1.9 18.3 143.0 5.3 12.4 45.2 0.0 19.0 64.8 24.4 16.5 15.4 5.6 9.7 0.0 0.8 53.2 26.8 1.6 5.0 55.0 2.8 6.1 9.7 5.5 212.6 1.8 4.0 7.2 40.3 0.8 21.8 0.0 41.7 124.7 36.4 3.0 0.4 0.6 22.2 11.2 22.2 2.3 81.9 0.0 9.2 10.9 1.9 16.2 1.2 4.3 2.6 1.5 0.9 3.8 7.0 GUSB ENSG00000169919 "Glucuronidase beta" P08236 7 65960684-65982215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 213.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036322, HPA036323" Approved Supported Vesicles "Intracellular and membrane" NA NA 330000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA036322: AB_10670796, HPA036323: AB_2675059" "unprognostic (1.54e-2)" "unprognostic (6.49e-2)" "unprognostic (1.18e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.89e-1)" "unprognostic (1.56e-3)" "unprognostic (1.32e-1)" "unprognostic (2.32e-1)" "unprognostic (7.00e-3)" "unprognostic (1.91e-1)" "unprognostic (3.34e-2)" "unprognostic (8.83e-3)" "unprognostic (1.98e-1)" "unprognostic (5.06e-1)" "unprognostic (1.45e-1)" 28.4 18.2 11.0 22.3 12.3 84.2 80.9 12.0 16.1 26.7 14.3 38.2 36.1 26.2 41.8 16.4 24.6 27.6 19.6 10.7 11.5 25.1 104.0 35.7 25.6 13.2 12.2 19.9 33.6 30.3 12.6 48.2 13.2 20.2 41.9 9.7 32.9 21.2 10.9 18.8 29.8 19.1 11.9 34.0 38.1 19.5 13.0 22.7 27.7 14.4 24.0 27.3 15.4 13.5 67.0 26.5 25.2 56.3 80.9 49.1 35.3 21.3 56.8 45.0 42.1 37.0 67.8 30.9 32.3 26.8 24.1 27.5 16.5 25.1 26.8 27.3 34.1 41.5 40.9 27.3 39.7 89.6 67.1 33.4 26.7 26.3 33.3 54.5 39.3 18.0 63.2 213.5 30.5 50.3 34.2 92.0 17.9 103.0 21.0 34.4 55.9 172.4 29.4 42.8 36.2 32.7 55.6 129.1 72.3 29.9 71.1 88.8 28.5 55.3 49.3 21.8 53.6 119.6 151.9 50.0 41.0 116.3 68.3 26.0 80.1 65.7 32.0 103.0 28.4 27.7 24.7 28.4 80.5 22.6 16.8 19.5 13.2 46.6 93.5 34.2 34.5 51.4 11.0 12.3 12.0 16.1 10.7 11.5 13.2 12.2 13.2 11.9 13.0 13.5 53.1 51.3 58.7 10.1 33.0 18.0 32.0 51.9 29.0 12.2 26.1 19.9 12.2 48.6 48.9 29.5 8.4 81.9 32.6 52.2 5.9 41.1 59.1 28.9 26.5 39.7 43.0 47.1 12.3 30.3 61.2 49.5 49.5 49.4 36.8 38.3 37.9 72.7 126.4 16.8 10.6 51.6 30.5 88.1 33.2 46.7 43.2 78.0 39.2 14.0 44.8 28.0 20.6 8.5 14.2 29.4 49.5 28.6 87.5 25.3 50.6 26.8 43.2 20.1 26.3 27.1 26.0 49.6 31.0 16.0 14.8 66.9 32.2 24.4 44.3 29.6 HACL1 "2-HPCL, HPCL, PHYH2" ENSG00000131373 "2-hydroxyacyl-CoA lyase 1" Q9UJ83 3 15560699-15601852 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 117.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 117.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035496, HPA035497, HPA073760" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles Nucleoplasm "HPA035496: AB_10601328, HPA035497: AB_2674653, HPA073760: AB_2686633" "unprognostic (6.64e-3)" "unprognostic (2.82e-2)" "unprognostic (2.24e-3)" "unprognostic (3.82e-1)" "unprognostic (4.08e-2)" "unprognostic (1.77e-1)" "unprognostic (2.96e-2)" "unprognostic (6.31e-2)" "unprognostic (8.27e-3)" "unprognostic (5.23e-2)" "unprognostic (3.30e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.63e-5)" "unprognostic (6.62e-2)" "unprognostic (2.66e-1)" "unprognostic (3.23e-2)" "unprognostic (9.07e-2)" 14.4 12.0 7.5 8.2 7.8 11.6 14.6 10.4 10.5 9.1 7.9 10.0 56.6 8.3 16.6 7.5 10.8 8.8 11.0 7.6 7.0 26.0 51.8 9.7 14.1 7.4 7.2 7.5 15.2 20.0 7.8 7.8 7.0 10.8 12.0 12.2 9.1 9.1 17.6 10.6 27.7 9.5 7.4 11.4 13.2 26.7 6.8 13.9 20.4 10.6 14.5 10.3 6.4 10.0 15.1 28.6 8.2 30.7 13.4 12.4 82.3 14.2 22.0 26.6 26.3 27.3 14.3 14.6 9.7 18.7 10.5 10.4 18.7 25.3 23.8 13.6 36.4 25.4 17.7 24.7 20.3 30.5 23.1 13.7 16.2 37.9 16.6 8.3 31.4 18.3 24.0 21.2 22.9 28.7 14.0 12.6 19.7 19.7 29.7 14.4 21.5 19.6 26.4 20.2 9.6 12.3 22.4 19.0 25.2 12.8 8.5 25.4 22.5 14.1 14.6 17.4 24.7 27.2 50.9 28.5 27.1 26.4 17.2 117.3 16.0 18.3 14.4 20.1 21.2 15.4 15.5 18.0 16.0 21.2 14.8 16.1 3.4 24.1 24.2 10.2 19.8 13.0 7.5 7.8 10.4 10.5 7.6 7.0 7.4 7.2 7.0 7.4 6.8 10.0 12.4 9.6 17.3 34.9 22.1 10.3 12.0 13.5 20.5 19.3 9.1 10.2 6.4 14.3 15.6 11.0 29.2 27.2 15.7 6.1 13.7 16.0 66.6 12.6 6.0 12.3 9.1 8.2 67.4 25.2 18.0 12.0 11.2 5.4 13.3 12.7 8.9 24.3 13.2 13.5 55.8 7.5 10.2 9.3 8.1 56.8 23.3 8.8 12.4 25.3 19.3 24.8 8.2 40.7 38.8 14.5 11.2 15.4 21.4 9.0 41.9 39.7 29.8 38.3 6.6 9.0 11.2 51.1 24.4 8.6 7.1 18.9 19.4 15.1 10.6 7.9 HAO2 "GIG16, HAOX2" ENSG00000116882 "Hydroxyacid oxidase 2" Q9NYQ3 1 119368779-119394130 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "kidney: 303.7;liver: 425.6" "Group enriched" "Detected in some" 7 "Hepatocytes: 256.8;Proximal tubular cells: 450.1" "Group enriched" "Detected in some" 26 "liver cancer: 25.6;renal cancer: 11.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050355 Uncertain Vesicles,Cytosol NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Vesicles "HPA050355: " "unprognostic (1.13e-1)" "unprognostic (1.68e-2)" "unprognostic (2.07e-1)" "unprognostic (1.00e-1)" "unprognostic (6.22e-2)" "unprognostic (5.33e-3)" "unprognostic (2.80e-2)" "unprognostic (3.27e-1)" "unprognostic (3.15e-1)" "unprognostic (3.17e-1)" "unprognostic (1.41e-1)" "unprognostic (1.73e-1)" "prognostic favorable (4.92e-4)" "unprognostic (9.66e-2)" "unprognostic (1.79e-1)" "unprognostic (2.89e-2)" "unprognostic (5.14e-4)" 0.0 0.6 0.2 0.1 0.6 0.0 0.6 0.1 0.6 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 303.7 425.6 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.1 0.4 0.2 0.1 0.3 23.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.1 0.6 0.2 0.0 0.2 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.7 0.0 11.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 0.0 0.0 0.6 0.0 13.5 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 4.2 256.8 0.1 0.0 0.1 0.0 0.0 6.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 450.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 HAPLN1 CRTL1 ENSG00000145681 "Hyaluronan and proteoglycan link protein 1" P10915 5 83637805-83720855 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "placenta: 75.0" "Cell type enhanced" "Detected in some" "Fibroblasts: 146.7;Granulosa cells: 43.2;Inhibitory neurons: 35.6;Syncytiotrophoblasts: 23.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "PC-3: 152.4;SuSa: 70.1;TIME: 91.8;U-2 OS: 139.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019105, HPA019482, HPA025238" Enhanced Approved Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA019105: AB_1850496, HPA019482: AB_1850498, HPA025238: " "unprognostic (5.74e-4)" "unprognostic (2.94e-2)" "unprognostic (6.58e-3)" "unprognostic (2.30e-2)" "unprognostic (1.30e-1)" "unprognostic (2.76e-3)" "unprognostic (6.01e-4)" "unprognostic (2.52e-2)" "unprognostic (1.70e-1)" "unprognostic (9.04e-3)" "unprognostic (1.31e-1)" "unprognostic (2.28e-2)" "prognostic unfavorable (4.81e-9)" "unprognostic (6.87e-2)" "unprognostic (2.04e-1)" "unprognostic (8.62e-2)" "unprognostic (3.91e-2)" 0.1 0.0 0.3 0.8 0.7 0.0 0.1 1.1 0.9 0.1 0.0 9.0 7.2 0.6 0.3 2.1 0.0 0.8 3.9 0.6 2.7 0.1 0.0 0.5 0.0 0.9 1.0 0.5 0.5 0.2 0.0 75.0 0.6 0.9 11.1 0.1 0.5 0.0 0.0 0.3 10.8 0.5 0.3 0.2 4.8 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 2.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.2 0.0 3.4 0.0 152.4 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 70.1 0.1 0.0 91.8 0.0 139.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 1.1 0.9 0.6 2.7 0.9 1.0 0.6 0.3 0.0 0.3 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 9.2 0.0 0.2 0.0 0.0 0.0 0.1 0.5 6.9 0.0 0.0 0.5 0.0 10.6 146.7 0.0 0.1 0.0 43.2 0.0 0.0 10.6 0.0 35.6 2.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 23.7 0.1 3.8 0.4 0.0 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 150.7;Kupffer cells: 155.5;Langerhans cells: 89.2;Macrophages: 170.1;Microglial cells: 52.5;monocytes: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 9 "THP-1: 69.3;U-937: 199.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 24.8 9.2 4.7 100.0 5.0 55.2 6.0 5.5 6.0 5.5 13.7 12.8 15.2 3.1 2.6 6.7 7.6 14.4 4.8 4.7 6.2 4.7 14.1 46.0 38.6 9.9 6.8 2.5 4.5 2.1 3.1 20.9 8.3 4.0 13.6 0.5 5.1 4.7 1.6 5.8 17.8 25.3 8.1 112.1 6.7 2.3 8.4 14.5 2.8 6.9 39.3 32.8 4.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.1 0.1 1.3 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 15.6 0.0 0.1 0.1 4.9 0.4 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.7 0.0 69.3 0.0 0.0 0.3 0.0 0.1 1.9 0.3 10.3 0.0 199.6 0.0 6.4 575.0 707.8 1.1 1059.1 1.3 48.4 1.1 1.1 336.3 43.0 1.1 0.9 801.3 11.0 1251.7 30.4 1.2 566.4 4.7 5.0 5.5 6.0 4.7 6.2 9.9 6.8 8.3 8.1 8.4 12.0 0.6 6.4 14.0 0.0 17.1 3.1 4.0 0.2 0.6 0.1 0.4 1.3 2.0 1.5 3.9 7.3 0.0 0.9 12.1 0.2 1.9 0.1 2.5 0.1 0.1 3.7 1.8 1.7 1.2 0.6 0.9 1.3 4.6 0.1 6.3 0.1 1.1 2.3 150.7 0.0 1.0 0.5 22.4 155.5 89.2 0.3 0.0 170.1 1.8 52.5 222.0 0.0 4.1 1.5 0.6 0.0 0.0 0.0 0.7 0.5 0.1 0.3 1.5 0.1 0.0 0.6 0.5 0.2 0.3 0.2 1.1 1.6 3.0 0.2 0.9 3.7 HEATR5B "DKFZp686P15184, KIAA1414" ENSG00000008869 "HEAT repeat containing 5B" Q9P2D3 2 36968383-37084372 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 62.3;Inhibitory neurons: 58.9;Oligodendrocyte precursor cells: 57.3;Oligodendrocytes: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042025, HPA055639" Approved Approved "Nuclear speckles,Vesicles,Cytosol" NA NA 6800 "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nuclear speckles, Vesicles, Cytosol" "HPA042025: AB_10959880, HPA055639: AB_2682870" "unprognostic (3.11e-2)" "unprognostic (1.65e-2)" "unprognostic (4.07e-1)" "unprognostic (6.05e-2)" "unprognostic (3.70e-2)" "unprognostic (7.75e-2)" "unprognostic (5.95e-2)" "unprognostic (3.33e-3)" "unprognostic (8.26e-2)" "unprognostic (3.08e-2)" "unprognostic (1.66e-1)" "unprognostic (8.07e-2)" "unprognostic (5.80e-3)" "unprognostic (8.69e-2)" "unprognostic (4.18e-1)" "unprognostic (2.72e-1)" "unprognostic (3.95e-1)" 9.7 8.8 7.1 15.0 7.1 24.3 14.5 11.7 9.8 9.9 4.9 9.9 10.8 9.5 16.9 11.7 8.1 10.7 9.7 7.4 6.4 9.3 9.3 10.8 31.9 5.8 5.2 9.8 18.2 13.4 6.3 10.2 6.4 11.4 13.5 24.3 14.3 7.7 4.9 18.2 11.5 8.3 3.9 19.0 12.3 9.6 7.0 24.7 11.8 9.4 31.2 10.1 8.5 8.1 16.2 8.1 11.7 17.8 11.9 11.7 14.9 10.1 7.4 9.0 9.1 9.6 10.9 34.6 7.1 8.6 11.9 13.4 11.6 8.2 11.7 17.0 12.6 22.6 11.3 13.1 7.4 24.5 28.5 10.8 11.2 13.0 12.3 9.9 15.5 18.3 21.6 29.8 10.9 9.6 21.5 17.4 7.7 16.7 5.6 20.5 11.9 26.3 10.5 13.8 14.3 12.6 10.6 16.7 7.8 11.7 12.0 7.9 17.2 13.5 7.7 9.9 7.9 18.5 16.2 39.0 11.0 14.3 9.0 18.3 5.0 12.3 7.7 2.8 7.1 9.7 8.5 8.7 9.0 14.0 8.7 7.6 5.2 7.5 4.4 11.2 9.7 5.9 7.1 7.1 11.7 9.8 7.4 6.4 5.8 5.2 6.4 3.9 7.0 8.1 12.9 22.4 10.3 35.9 20.8 9.8 4.2 4.7 6.8 13.0 11.9 8.3 20.8 8.6 7.1 5.5 10.4 7.0 24.4 11.3 1.9 4.6 6.3 14.8 10.0 9.5 5.4 18.7 62.3 6.2 6.2 9.4 25.5 11.1 7.0 9.8 11.7 7.8 6.3 16.8 58.9 8.9 6.1 17.0 15.7 2.6 9.0 13.2 7.2 56.2 9.2 6.5 16.5 57.3 69.7 8.8 6.3 6.4 17.6 5.5 12.7 5.4 12.8 16.2 19.7 6.5 10.6 3.6 11.2 11.7 11.6 5.6 14.5 7.7 8.7 4.9 HEXA ENSG00000213614 "Hexosaminidase subunit alpha" P06865 15 72340924-72376420 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 234.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018082, HPA054583" Supported Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 20000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles Cytosol "HPA018082: , HPA054583: AB_2682531" "unprognostic (1.51e-2)" "unprognostic (1.73e-2)" "unprognostic (3.41e-1)" "prognostic favorable (5.63e-8)" "unprognostic (6.58e-2)" "unprognostic (1.32e-2)" "unprognostic (1.34e-2)" "unprognostic (2.82e-2)" "unprognostic (3.75e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (9.98e-2)" "unprognostic (3.98e-1)" "unprognostic (7.05e-3)" "unprognostic (3.02e-2)" "unprognostic (4.73e-2)" "unprognostic (8.69e-2)" 49.8 56.1 18.3 37.6 21.1 110.0 58.5 20.4 21.6 73.8 28.5 55.1 49.8 42.6 164.6 24.8 47.8 76.7 54.3 19.9 20.1 90.1 79.4 84.2 54.2 23.0 21.3 39.3 30.6 54.0 26.3 102.0 24.6 45.3 67.0 32.1 45.0 53.3 22.1 21.8 41.2 59.5 21.7 54.7 45.1 35.6 27.0 38.1 76.5 33.2 42.4 71.6 19.7 29.9 39.8 66.4 27.8 53.8 223.6 253.1 39.7 54.8 274.1 115.3 182.8 34.6 282.7 32.9 50.9 110.0 59.9 77.1 74.5 34.6 72.5 26.5 30.0 41.4 60.4 60.9 172.9 99.9 113.1 216.7 101.3 50.4 89.3 210.3 107.4 48.4 65.1 197.6 156.0 33.9 21.7 50.0 16.0 128.9 0.3 22.3 60.6 75.3 129.1 61.6 23.8 26.4 136.5 126.6 307.3 56.1 23.4 123.9 54.1 171.9 70.7 160.1 59.3 104.7 151.8 33.4 62.1 130.4 85.3 24.2 84.6 60.1 43.8 35.7 38.7 41.1 28.8 38.9 98.0 38.0 22.5 33.2 8.1 51.3 13.3 37.3 28.2 63.0 18.3 21.1 20.4 21.6 19.9 20.1 23.0 21.3 24.6 21.7 27.0 29.9 68.9 64.1 62.4 19.9 46.3 22.2 33.3 94.3 19.4 42.4 28.6 30.4 26.9 30.0 68.0 66.2 106.3 150.2 54.2 36.6 60.7 88.3 20.6 27.2 30.2 50.8 47.2 19.1 22.7 38.0 68.0 78.7 42.8 40.6 29.9 49.9 43.5 42.9 234.3 26.9 24.7 46.3 81.4 92.8 75.0 13.7 74.3 118.1 94.3 24.4 60.3 38.4 82.4 20.6 26.7 39.1 74.6 44.8 37.7 33.0 68.5 66.7 37.5 56.9 46.0 24.5 31.7 24.3 32.3 13.5 15.6 157.6 36.7 45.2 50.6 27.5 HFM1 "FLJ36760, FLJ39011, MER3, SEC63D1" ENSG00000162669 "Helicase for meiosis 1" A2PYH4 1 91260766-91404856 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Meiosis "Helicase, Hydrolase" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 9.3;testis: 13.8" "Cell type enhanced" "Detected in some" "Astrocytes: 50.9;Inhibitory neurons: 38.4;Oligodendrocyte precursor cells: 90.5;Spermatocytes: 58.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.2;AN3-CA: 2.8;K-562: 3.0;SH-SY5Y: 2.1;U-266/70: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035036, HPA035557" Supported "Golgi apparatus,Vesicles" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA035036: AB_2797224, HPA035557: AB_10696507" "unprognostic (1.35e-2)" "unprognostic (9.39e-2)" "unprognostic (1.17e-1)" "unprognostic (2.83e-4)" "unprognostic (2.05e-2)" "unprognostic (1.52e-1)" "unprognostic (7.43e-3)" "unprognostic (1.79e-1)" "unprognostic (7.75e-2)" "unprognostic (7.97e-2)" "unprognostic (1.76e-4)" "unprognostic (2.81e-2)" "unprognostic (1.06e-2)" "unprognostic (2.89e-3)" "unprognostic (2.78e-2)" "unprognostic (1.77e-4)" "unprognostic (9.59e-2)" 0.4 0.3 1.0 0.1 1.0 0.2 0.4 5.1 1.0 0.9 0.0 0.5 0.3 2.3 1.1 0.1 0.8 0.2 0.6 0.7 1.6 0.7 0.1 0.2 0.1 1.7 1.6 3.9 0.7 0.1 9.3 0.5 1.1 0.6 0.3 4.5 0.5 1.1 1.5 0.1 0.2 0.9 1.1 0.4 0.2 13.8 1.6 0.1 1.6 1.1 0.2 0.4 0.3 1.3 0.0 0.1 5.2 2.8 0.0 0.1 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.1 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.3 0.1 1.6 0.0 0.0 0.2 1.0 0.0 0.0 0.0 1.7 2.1 0.0 0.0 0.7 1.4 0.0 0.5 0.0 0.0 0.5 0.5 0.1 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 5.1 1.0 0.7 1.6 1.7 1.6 1.1 1.1 1.6 1.3 0.2 0.0 1.1 50.9 0.0 0.0 0.0 0.0 0.6 3.9 0.1 0.3 3.1 0.0 0.0 0.0 6.2 0.5 0.0 0.0 0.0 0.4 17.8 0.2 1.9 0.4 0.0 2.5 17.6 0.2 0.2 0.6 0.0 0.0 0.0 5.9 0.0 0.0 0.1 0.0 38.4 0.0 0.0 0.0 0.0 5.0 4.1 0.0 0.0 10.3 0.0 2.4 0.0 90.5 9.5 0.1 0.0 2.2 0.0 0.1 0.0 0.0 0.0 6.2 0.0 2.0 1.4 58.9 15.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 HIP1 ILWEQ ENSG00000127946 "Huntingtin interacting protein 1" O00291 7 75533298-75738962 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Apoptosis, Differentiation, Endocytosis, Transcription, Transcription regulation" "Actin-binding, Activator" "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1373.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 9.5;eosinophil: 6.8;neutrophil: 6.8;NK-cell: 3.0;plasmacytoid DC: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013606, CAB015334, CAB016402, HPA017964" Enhanced Supported Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB015334: AB_2117565, CAB016402: AB_627725, HPA013606: AB_1850717, HPA017964: AB_1850719" "unprognostic (8.23e-2)" "unprognostic (1.22e-1)" "unprognostic (2.20e-2)" "unprognostic (1.64e-1)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "unprognostic (2.73e-3)" "unprognostic (1.03e-2)" "unprognostic (1.11e-2)" "unprognostic (2.02e-2)" "unprognostic (2.70e-2)" "unprognostic (7.98e-2)" "unprognostic (1.73e-3)" "unprognostic (9.67e-2)" "unprognostic (1.75e-1)" "unprognostic (1.00e-2)" "unprognostic (1.09e-1)" 16.7 7.9 23.6 7.3 38.7 5.4 13.2 29.8 29.0 11.7 14.4 6.1 2.7 9.8 9.2 5.3 12.9 8.3 9.0 22.4 24.9 14.8 9.3 18.5 4.7 34.6 35.4 8.0 3.8 4.2 3.4 19.7 32.0 6.8 4.1 4.6 4.0 11.2 4.2 10.6 5.0 12.2 24.5 11.2 4.8 30.4 34.8 3.1 15.3 8.4 4.5 9.0 7.9 50.9 5.2 55.9 37.1 35.2 15.3 20.8 11.1 9.7 6.3 6.2 4.6 3.2 5.0 3.8 11.2 24.2 21.6 6.3 38.1 8.0 8.3 3.1 7.1 3.0 6.6 5.3 15.2 0.8 14.8 16.0 4.8 20.4 4.2 11.4 26.3 4.2 4.0 3.6 10.1 21.6 2.5 22.2 40.5 0.5 6.6 4.4 15.5 0.3 4.7 20.0 1.8 16.2 9.0 5.6 12.5 32.8 34.6 13.9 9.4 18.0 13.7 6.2 13.6 4.0 0.4 8.9 18.1 8.0 12.4 9.5 0.9 6.8 0.9 0.9 0.7 0.3 0.1 0.7 1.4 0.4 0.1 0.5 6.8 3.0 0.7 3.3 1.4 0.3 23.6 38.7 29.8 29.0 22.4 24.9 34.6 35.4 32.0 24.5 34.8 50.9 54.0 60.9 37.5 43.8 7.8 17.6 6.2 7.1 20.5 12.0 14.8 10.7 14.3 11.5 12.2 27.6 12.5 2.1 27.2 2.2 13.7 14.4 256.9 15.5 24.2 54.3 4.8 7.8 16.3 6.0 10.0 17.1 6.1 25.5 14.0 25.9 36.8 22.5 14.9 23.5 19.0 3.0 6.1 18.5 49.1 1373.3 22.4 24.1 10.6 45.9 9.4 14.3 21.6 336.3 313.7 3.1 7.7 24.8 18.4 4.2 0.3 2.6 1.3 9.4 85.5 25.9 44.8 12.1 5.6 5.6 9.1 0.8 13.5 7.7 3.3 3.5 HIP1R "FLJ14000, HIP12, HIP3, ILWEQ, KIAA0655" ENSG00000130787 "Huntingtin interacting protein 1 related" O75146 12 122834453-122862961 "Cancer-related genes, Predicted intracellular proteins" Endocytosis Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 103.4" "Cell type enhanced" "Detected in many" "Astrocytes: 134.5;Oligodendrocyte precursor cells: 168.9;Oligodendrocytes: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.3;naive B-cell: 10.6" "Group enriched" "Detected in many" 8 "B-cells: 10.6;granulocytes: 2.9;T-cells: 3.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017187, HPA038135, HPA038136" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Cytosol" Vesicles "CAB017187: , HPA038135: AB_2675851, HPA038136: AB_2675852" "unprognostic (4.52e-1)" "unprognostic (6.39e-2)" "unprognostic (7.07e-2)" "unprognostic (6.55e-3)" "unprognostic (8.67e-2)" "unprognostic (1.00e-2)" "unprognostic (1.02e-2)" "unprognostic (8.11e-2)" "unprognostic (6.37e-2)" "unprognostic (1.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.72e-2)" "prognostic favorable (6.50e-7)" "unprognostic (2.18e-2)" "unprognostic (2.84e-1)" "unprognostic (2.54e-3)" "prognostic favorable (7.26e-4)" 18.5 24.0 68.6 10.4 95.5 13.3 22.6 78.8 80.3 16.0 33.5 16.3 31.8 9.0 3.8 18.0 9.0 7.7 18.9 68.0 67.8 50.2 25.6 15.4 17.5 87.3 83.8 5.6 50.2 8.9 42.0 4.7 75.6 21.0 4.9 5.5 58.7 10.5 7.2 51.7 36.0 2.2 65.3 20.9 66.7 8.5 85.7 12.6 21.5 4.4 11.7 11.4 19.7 103.4 38.1 10.8 8.0 33.1 2.3 6.1 39.2 5.9 9.5 5.9 4.6 16.8 11.1 36.0 19.0 4.3 8.9 32.4 9.7 21.4 0.5 5.8 14.0 0.8 13.8 17.8 7.1 2.8 24.5 3.8 14.9 8.0 13.4 8.1 40.5 16.5 9.6 2.0 3.4 54.4 17.4 8.8 7.4 32.8 12.8 9.0 10.2 12.5 19.6 45.4 8.1 17.9 7.1 18.0 9.5 4.3 36.6 1.5 32.8 3.7 27.5 11.7 5.7 24.8 14.2 21.8 6.0 6.0 3.1 0.0 0.0 2.9 2.7 0.0 1.5 9.3 1.7 2.1 0.0 10.6 3.0 1.9 0.2 0.7 0.0 0.0 0.4 2.0 68.6 95.5 78.8 80.3 68.0 67.8 87.3 83.8 75.6 65.3 85.7 103.4 57.0 0.0 13.4 134.5 38.0 13.3 16.8 8.4 6.8 16.4 21.2 18.2 4.2 60.1 11.1 60.7 29.2 3.7 18.2 28.4 0.0 40.1 3.1 21.9 4.7 18.2 7.8 1.3 11.2 28.7 13.1 2.3 80.5 37.5 5.7 25.3 19.2 24.4 0.6 18.5 9.7 29.9 22.4 1.2 4.2 2.9 1.5 2.2 10.6 9.4 0.1 12.5 7.2 168.9 117.8 22.7 25.3 1.2 17.2 20.2 47.5 17.9 14.2 16.6 0.0 2.5 4.1 6.5 13.3 11.5 21.0 1.9 15.0 1.3 23.9 28.4 HLA-DMB "D6S221E, RING7" ENSG00000242574 "Major histocompatibility complex, class II, DM beta" P28068 6 32934629-32941028 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 78.8;lymphoid tissue: 101.5" "Group enriched" "Detected in many" 4 "B-cells: 228.5;dendritic cells: 129.4;Hofbauer cells: 274.8;Kupffer cells: 201.9;Langerhans cells: 472.8;Macrophages: 272.4;monocytes: 187.1;Proximal enterocytes: 284.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 128.8;dendritic cells: 85.3;monocytes: 73.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 14.2;Daudi: 27.6;EFO-21: 12.4;U-266/70: 7.8;U-698: 31.9" "Low region specificity" "Detected in all" "HPA012298, HPA077524" Supported Supported Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA012298: AB_1853927, HPA077524: " "unprognostic (5.34e-2)" "unprognostic (1.63e-2)" "unprognostic (2.45e-2)" "prognostic favorable (3.89e-5)" "unprognostic (3.07e-1)" "unprognostic (7.64e-3)" "unprognostic (4.00e-1)" "unprognostic (3.46e-3)" "unprognostic (6.99e-2)" "unprognostic (8.76e-2)" "unprognostic (8.93e-2)" "unprognostic (2.73e-1)" "unprognostic (6.82e-3)" "unprognostic (2.03e-1)" "unprognostic (4.14e-2)" "unprognostic (8.35e-2)" "unprognostic (5.60e-2)" 38.3 35.9 0.1 13.2 0.2 6.9 25.7 0.3 1.0 21.6 0.1 19.9 0.0 14.6 7.4 9.3 14.6 0.1 11.1 0.0 0.6 41.9 7.8 59.9 17.6 0.3 0.4 9.5 9.1 0.0 9.2 0.8 0.2 13.1 14.9 0.5 14.7 0.0 5.3 14.3 78.8 0.0 0.9 101.5 17.6 2.2 0.1 9.9 45.9 0.0 18.8 14.4 10.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 27.6 12.4 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 7.8 0.4 31.9 0.0 0.1 0.0 0.5 73.2 16.7 1.2 73.8 2.6 94.0 1.0 2.9 85.0 128.8 0.7 2.4 4.7 16.2 28.1 85.3 6.7 71.4 0.1 0.2 0.3 1.0 0.0 0.6 0.3 0.4 0.2 0.9 0.1 1.1 36.8 9.6 57.0 0.7 228.5 12.0 1.0 5.4 2.2 0.2 2.5 4.7 2.6 5.7 12.7 16.5 0.0 1.7 129.4 3.3 11.7 28.8 0.5 7.5 5.4 37.2 4.2 10.3 0.8 4.4 1.6 3.8 3.1 38.5 15.2 22.7 5.7 0.5 274.8 0.0 0.6 8.5 2.0 201.9 472.8 1.5 3.4 272.4 16.0 27.2 187.1 0.5 21.6 1.0 0.1 2.5 17.8 1.9 3.8 1.3 284.8 7.4 16.8 1.1 6.6 1.6 3.1 0.6 0.7 1.1 10.9 2.7 17.6 0.9 10.3 8.7 HLA-DPA1 HLA-DP1A ENSG00000231389 "Major histocompatibility complex, class II, DP alpha 1" P20036 6 33064569-33080775 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 319.9;lymphoid tissue: 359.6" "Cell type enhanced" "Detected in many" "B-cells: 1387.3;Kupffer cells: 1794.6;Langerhans cells: 8122.8;Macrophages: 2736.9;monocytes: 2940.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 81.8;intermediate monocyte: 187.4;memory B-cell: 150.4;myeloid DC: 296.0;naive B-cell: 136.5;non-classical monocyte: 124.1;plasmacytoid DC: 82.6" "Group enriched" "Detected in all" 7 "B-cells: 150.4;dendritic cells: 296.0;monocytes: 187.4" "Cell line enhanced" "Detected in many" "Daudi: 37.2;HDLM-2: 115.9;REH: 30.3;U-698: 26.1" HPA017967 Enhanced Supported Vesicles NA NA 240000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA017967: AB_1853929" "unprognostic (8.93e-3)" "unprognostic (3.15e-2)" "unprognostic (3.64e-2)" "unprognostic (9.40e-3)" "unprognostic (9.07e-2)" "unprognostic (2.80e-2)" "unprognostic (5.69e-2)" "unprognostic (1.82e-2)" "unprognostic (7.28e-2)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (1.80e-1)" "unprognostic (8.38e-2)" "unprognostic (1.17e-1)" "unprognostic (4.69e-2)" "unprognostic (8.11e-2)" "unprognostic (1.06e-1)" 180.8 108.0 2.2 33.4 2.0 12.8 138.4 2.7 3.3 76.7 2.5 72.1 20.2 55.3 8.3 43.1 63.0 13.0 62.0 2.0 3.4 99.0 36.8 319.9 51.3 4.9 2.8 24.9 28.6 5.9 58.0 3.4 4.3 64.0 16.1 2.0 59.5 16.2 29.5 66.3 174.4 14.6 4.3 359.6 52.1 13.4 3.1 30.2 76.6 7.3 51.5 58.6 60.0 4.4 0.1 0.0 0.0 0.0 0.8 1.3 1.1 0.4 0.4 0.5 0.0 0.0 4.9 37.2 5.0 0.9 7.1 0.0 0.0 0.0 0.1 115.9 2.5 6.2 0.0 0.0 0.1 0.0 11.6 1.7 0.0 2.2 0.0 0.0 0.6 0.0 0.0 3.3 0.0 0.0 0.1 0.1 0.6 0.0 0.0 30.3 0.0 4.9 0.1 0.0 0.1 0.0 0.0 0.0 2.9 0.0 0.0 1.3 2.6 7.8 0.1 0.1 0.0 5.6 0.9 26.1 12.2 0.2 4.4 2.2 81.8 6.6 21.6 187.4 5.7 150.4 9.6 23.9 296.0 136.5 3.4 15.7 3.0 20.9 124.1 82.6 29.2 136.0 2.2 2.0 2.7 3.3 2.0 3.4 4.9 2.8 4.3 4.3 3.1 4.4 621.8 83.3 404.3 0.3 1387.3 206.7 7.2 12.4 9.1 2.8 41.2 110.4 12.1 64.3 107.3 23.9 0.0 4.2 574.9 10.6 9.8 36.4 2.8 1.2 4.1 337.8 10.2 80.3 0.5 18.8 9.3 53.7 48.4 2.8 64.6 14.3 62.2 7.5 1153.8 5.0 0.9 18.2 12.2 1794.6 8122.8 11.7 18.0 2736.9 302.4 32.8 2940.3 5.1 94.7 0.0 0.1 4.7 5.4 27.4 100.2 10.6 114.0 42.7 129.2 5.0 52.6 14.7 29.8 1.3 4.8 6.0 175.2 6.8 157.8 11.5 28.6 34.4 HOOK2 HK2 ENSG00000095066 "Hook microtubule tethering protein 2" Q96ED9 19 12763003-12872740 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 291.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 83.7;RT4: 100.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043519, HPA050351" Approved Supported Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Vesicles, Cytosol" "HPA043519: AB_2678525, HPA050351: AB_2681102" "unprognostic (4.26e-1)" "unprognostic (3.80e-2)" "unprognostic (2.53e-3)" "unprognostic (1.16e-1)" "unprognostic (4.57e-1)" "unprognostic (1.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.25e-3)" "unprognostic (3.06e-2)" "unprognostic (2.52e-2)" "unprognostic (1.75e-3)" "prognostic unfavorable (7.59e-5)" "prognostic favorable (3.28e-4)" "unprognostic (3.27e-3)" "unprognostic (5.74e-2)" "unprognostic (1.54e-1)" "unprognostic (2.91e-2)" 40.0 20.6 15.8 10.3 15.1 4.1 45.8 15.5 21.0 31.4 14.3 35.8 52.0 15.1 46.8 55.5 27.0 20.9 63.3 14.8 15.2 54.9 46.8 24.0 7.1 15.3 14.3 24.9 98.1 38.4 113.8 14.2 15.5 53.1 25.0 13.4 59.3 26.8 70.7 56.2 43.1 10.7 12.7 18.0 41.8 24.7 14.8 7.5 96.2 34.0 13.3 25.1 39.3 15.5 38.5 9.7 11.3 8.0 12.5 11.5 40.5 11.9 5.6 6.5 8.3 33.3 44.2 7.5 20.8 11.5 5.7 48.6 12.0 34.3 6.8 19.7 8.8 7.5 21.1 11.0 5.9 4.2 10.2 14.0 32.4 8.3 13.4 15.0 3.9 14.6 12.6 5.7 13.6 83.7 4.3 7.8 4.8 24.9 10.2 12.1 7.1 18.6 13.4 100.5 28.1 14.5 8.7 25.7 7.3 11.5 35.3 9.1 7.2 12.6 8.5 19.7 4.2 20.6 23.9 4.5 13.4 14.2 9.3 0.2 0.8 0.0 1.4 1.3 0.9 1.7 1.8 0.6 1.3 1.2 3.0 1.9 1.0 1.3 0.8 0.6 0.4 1.1 15.8 15.1 15.5 21.0 14.8 15.2 15.3 14.3 15.5 12.7 14.8 15.5 14.8 19.2 38.0 25.1 34.4 50.5 99.8 135.0 158.8 117.7 84.4 62.9 29.6 75.8 84.5 82.8 100.1 85.0 11.9 137.2 43.0 77.5 9.2 26.2 21.0 18.6 63.0 11.1 28.9 45.4 40.2 24.2 140.2 39.3 12.6 30.7 22.1 24.4 16.6 63.9 43.3 93.9 118.0 11.1 21.6 9.1 27.1 20.4 28.4 6.5 19.7 26.6 10.3 17.1 10.6 46.7 98.0 26.7 30.1 131.6 291.7 45.4 49.3 84.5 13.1 24.5 25.4 73.9 26.1 82.1 65.5 128.1 27.9 42.1 95.6 87.1 HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 16.4;Kupffer cells: 41.5;Macrophages: 20.2;monocytes: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.2;neutrophil: 18.5" "Group enriched" "Detected in many" 4 "granulocytes: 18.5;monocytes: 27.2" "Cell line enhanced" "Detected in many" "Karpas-707: 39.8;OE19: 40.1;TIME: 25.8" "Region enhanced" "Detected in some" "olfactory bulb: 3.7" "Low region specificity" "Detected in all" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" No No 6500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Vesicles "CAB009813: AB_2120854, HPA055344: " "unprognostic (6.57e-2)" "unprognostic (1.22e-2)" "unprognostic (9.13e-2)" "unprognostic (5.92e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.24e-2)" "unprognostic (5.65e-2)" "unprognostic (7.06e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (9.62e-3)" "unprognostic (3.27e-1)" "unprognostic (2.78e-1)" "unprognostic (3.04e-3)" "unprognostic (4.15e-2)" "unprognostic (3.70e-3)" 3.4 4.5 0.8 6.6 0.9 2.3 1.0 0.6 1.7 2.4 0.4 5.9 2.1 2.7 0.2 9.9 3.9 2.7 0.8 0.9 0.9 1.6 2.4 3.2 4.5 1.8 1.0 4.5 0.8 5.6 1.2 2.1 1.3 0.6 6.4 0.2 9.7 0.6 0.3 5.3 2.8 1.9 1.8 6.0 2.0 5.7 2.7 2.0 0.7 0.3 3.9 3.0 3.3 3.6 13.5 0.6 0.1 1.7 3.2 0.9 0.1 1.5 8.2 3.6 16.5 0.0 11.0 0.4 2.3 4.2 20.8 12.3 16.8 2.5 6.5 1.4 1.7 4.2 9.0 0.2 1.4 2.5 8.4 1.8 5.1 2.4 15.4 1.4 18.1 2.4 0.1 39.8 1.5 2.8 0.2 0.3 0.7 40.1 2.6 0.0 0.4 0.6 10.2 0.3 9.3 0.0 17.7 9.8 1.4 2.6 1.5 3.8 25.8 1.5 4.6 1.4 1.7 0.5 6.2 0.2 9.9 11.4 2.7 0.4 27.2 0.0 1.4 10.1 1.0 0.2 2.7 1.0 3.0 0.3 1.7 1.6 18.5 2.3 1.5 0.1 5.2 7.9 0.8 0.9 0.6 1.7 0.9 0.9 1.8 1.0 1.3 1.8 2.7 3.6 0.3 6.4 4.4 0.0 0.7 3.4 3.0 3.3 2.8 0.0 0.3 0.5 0.6 0.0 5.6 1.8 0.0 0.5 2.4 10.1 0.0 1.9 0.6 2.3 3.7 1.0 6.6 2.7 0.8 1.3 2.9 1.4 4.1 13.2 0.0 0.4 2.9 0.6 16.4 0.0 3.8 2.8 0.0 41.5 3.0 0.3 0.6 20.2 0.0 7.5 33.9 0.0 3.1 0.0 0.1 1.1 6.7 0.0 0.7 1.7 4.1 0.0 2.8 0.0 0.0 0.1 1.2 0.2 1.0 4.0 3.7 1.5 6.2 1.4 4.6 3.7 HSD11B1L "HSD1L, SCDR10, SDR26C2" ENSG00000167733 "Hydroxysteroid 11-beta dehydrogenase 1 like" Q7Z5J1 19 5680604-5688523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 58.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 19.0" "Low region specificity" "Detected in all" HPA049078 Supported Vesicles "Secreted in brain" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA049078: AB_2680622" "unprognostic (2.34e-2)" "unprognostic (1.10e-1)" "unprognostic (4.73e-3)" "unprognostic (5.26e-2)" "unprognostic (9.37e-2)" "prognostic favorable (4.38e-4)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (1.18e-3)" "unprognostic (1.43e-1)" "unprognostic (3.33e-2)" "unprognostic (1.75e-1)" "unprognostic (5.77e-2)" "unprognostic (4.52e-1)" "unprognostic (1.73e-2)" 3.9 9.8 46.6 1.3 46.7 2.6 5.1 32.0 58.2 5.5 34.0 8.4 1.6 5.4 5.1 3.7 6.7 3.0 5.9 46.1 41.8 12.4 5.4 4.4 1.4 38.4 36.5 6.7 7.0 7.3 21.2 1.5 37.2 6.1 1.0 6.3 5.8 4.1 10.9 9.3 3.4 1.6 32.9 3.2 6.3 8.1 42.4 1.6 8.6 3.3 1.0 6.0 4.3 39.1 3.6 3.0 11.3 2.1 5.0 5.7 2.2 2.7 4.4 1.1 4.8 1.3 3.3 0.8 5.9 2.2 0.9 1.7 1.4 1.8 1.0 3.2 3.6 2.3 3.0 2.2 3.6 0.9 7.9 5.5 3.9 1.6 1.6 10.4 1.8 5.1 2.4 2.9 4.6 0.3 2.1 2.1 3.0 14.2 4.1 3.6 0.5 3.1 9.5 0.8 3.2 19.0 0.5 1.6 12.8 3.8 2.6 0.7 3.2 2.7 5.0 4.9 2.2 7.6 2.8 0.9 7.7 1.2 2.4 1.5 1.0 0.5 0.6 2.7 0.6 0.5 1.4 1.6 1.0 1.1 1.8 1.7 1.9 0.7 1.8 2.2 0.4 0.9 46.6 46.7 32.0 58.2 46.1 41.8 38.4 36.5 37.2 32.9 42.4 39.1 8.2 0.0 2.6 13.7 2.6 8.2 8.6 12.9 9.6 11.3 23.7 23.1 2.3 10.0 8.6 23.9 14.6 4.7 3.0 4.5 15.6 12.4 9.5 21.8 6.0 6.1 25.7 1.3 24.7 4.7 6.5 8.1 4.6 5.4 10.2 12.4 8.9 4.1 5.1 8.4 20.4 4.6 12.2 2.8 6.0 13.9 7.2 2.4 5.4 1.9 3.1 30.5 1.0 14.1 4.6 4.8 4.3 12.8 0.9 8.4 4.1 33.3 31.2 12.9 0.0 8.1 9.5 10.8 12.7 4.8 10.2 2.9 3.1 16.6 3.7 9.7 ICA1 "ICA69, ICAp69" ENSG00000003147 "Islet cell autoantigen 1" Q05084 7 8113184-8262687 "Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 594.7;Late spermatids: 867.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "T-reg: 29.9" "Lineage enriched" "Detected in many" 9 "T-cells: 29.9" "Cell line enhanced" "Detected in many" "CAPAN-2: 47.1;MCF7: 42.5;OE19: 48.4;RT4: 49.4;SCLC-21H: 66.1;SH-SY5Y: 105.8;SK-BR-3: 52.1;T-47d: 43.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017646, HPA061452" Approved Supported Vesicles,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 25: Pancreas - Digestion" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Vesicles, Cytosol" "HPA017646: AB_1851382, HPA061452: AB_2684525" "unprognostic (1.39e-1)" "unprognostic (1.37e-1)" "unprognostic (3.74e-1)" "unprognostic (6.83e-3)" "unprognostic (9.49e-2)" "unprognostic (8.57e-3)" "unprognostic (1.37e-2)" "unprognostic (3.54e-1)" "unprognostic (7.61e-2)" "unprognostic (3.42e-1)" "unprognostic (5.84e-2)" "unprognostic (2.62e-1)" "prognostic favorable (4.23e-8)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (2.77e-2)" "unprognostic (4.08e-2)" 15.8 10.4 11.3 5.7 16.2 23.8 21.1 21.5 21.8 16.4 1.2 22.8 13.6 6.8 13.6 9.5 13.7 11.1 44.3 13.4 9.3 16.0 8.8 11.2 13.5 8.0 9.5 1.7 62.7 20.9 19.8 8.2 9.3 22.1 23.5 2.9 37.1 4.9 2.8 12.8 17.8 5.6 5.1 12.4 30.5 24.2 13.3 5.0 14.1 3.3 9.6 13.8 7.4 15.3 0.0 1.5 1.7 0.2 0.2 0.0 4.2 0.0 0.0 0.6 0.2 1.0 47.1 0.3 5.2 0.1 0.9 0.0 0.8 1.9 0.0 0.0 6.8 9.1 0.9 0.0 0.4 9.1 1.8 0.0 3.0 0.0 0.0 0.5 31.5 8.2 26.4 0.0 0.0 42.5 0.4 0.0 9.9 48.4 0.4 0.0 0.0 19.5 19.0 49.4 66.1 105.8 0.0 52.1 0.7 11.6 43.4 14.3 19.8 0.0 0.9 0.2 1.0 14.1 7.5 0.0 0.0 6.9 10.3 1.0 2.4 0.2 0.3 0.8 0.6 0.4 5.4 0.4 2.4 0.7 0.3 0.2 3.4 0.9 0.4 0.6 29.9 1.3 11.3 16.2 21.5 21.8 13.4 9.3 8.0 9.5 9.3 5.1 13.3 15.3 73.4 28.9 24.4 6.5 1.6 20.5 16.2 7.1 9.1 10.4 42.8 28.7 43.2 22.8 20.1 22.0 6.2 2.7 2.1 28.2 43.0 38.4 594.7 34.2 5.8 44.1 77.2 16.4 132.1 74.8 0.8 4.5 56.1 65.4 8.2 11.2 42.1 1.3 23.9 0.0 138.0 80.5 44.7 8.1 9.3 867.0 7.5 9.6 14.2 60.0 6.3 0.8 3.1 49.3 3.9 59.8 53.1 3.0 1.7 53.8 23.8 8.3 17.8 1.7 6.6 1.2 5.6 13.9 9.6 18.4 8.9 2.2 9.5 4.7 41.8 42.7 IDUA "MPS1, MPSI" ENSG00000127415 Alpha-L-iduronidase P35475 4 986997-1004564 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 29.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025901, HPA046979, HPA054254" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 170000 "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB025901: , HPA046979: AB_2679888, HPA054254: AB_2682429" "unprognostic (3.62e-2)" "unprognostic (9.08e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (7.23e-2)" "unprognostic (1.45e-1)" "unprognostic (2.31e-2)" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.43e-2)" "unprognostic (1.89e-3)" "unprognostic (2.64e-2)" "unprognostic (4.61e-3)" "prognostic unfavorable (7.87e-5)" "unprognostic (2.24e-1)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "prognostic favorable (8.04e-5)" 13.5 17.6 3.4 2.2 3.4 2.9 16.1 9.2 7.5 17.5 2.9 10.3 3.6 15.4 2.4 9.9 16.3 3.7 11.6 3.8 1.5 15.9 13.6 13.9 3.5 3.2 2.1 17.0 21.0 2.8 17.2 1.7 2.4 18.5 1.8 1.8 16.6 4.5 3.7 8.9 14.3 2.0 1.0 18.9 17.1 5.6 2.9 3.4 17.0 0.7 1.3 12.0 13.9 2.6 1.8 0.4 0.0 1.1 12.7 3.6 5.3 10.7 8.5 1.2 1.7 0.6 6.4 0.8 10.7 5.0 1.0 0.5 0.1 0.3 0.4 6.1 0.6 1.0 0.8 0.1 5.8 0.8 4.6 9.3 3.1 0.6 0.0 3.4 1.0 0.7 0.6 0.0 1.6 0.0 2.2 2.5 0.8 11.9 5.5 2.7 0.0 1.1 3.5 0.9 0.1 3.3 0.3 0.0 5.7 1.3 1.2 2.3 9.3 9.0 1.6 2.6 1.2 29.0 1.4 0.4 7.8 3.3 1.8 0.0 1.5 0.0 1.4 1.2 1.8 0.1 1.1 0.9 1.8 0.2 1.3 0.7 0.0 1.5 1.7 1.1 0.6 0.5 3.4 3.4 9.2 7.5 3.8 1.5 3.2 2.1 2.4 1.0 2.9 2.6 8.7 6.4 5.0 4.9 5.2 3.6 11.5 1.1 8.6 2.0 8.5 9.1 2.6 1.5 1.5 7.3 4.2 0.4 4.3 5.0 0.0 1.6 0.9 4.1 9.0 4.9 10.7 1.3 4.4 2.4 1.7 13.4 16.8 6.0 2.5 8.2 6.1 2.6 6.5 0.0 2.9 4.2 0.0 5.0 3.6 0.9 19.6 7.3 5.4 1.0 1.6 1.1 4.1 5.5 3.3 1.4 6.9 10.5 15.7 7.7 6.9 1.4 1.4 2.1 0.0 5.5 4.4 3.7 1.6 4.7 1.8 0.4 5.6 4.7 4.3 7.9 IFI30 "GILT, IFI-30, IP-30, IP30, MGC32056" ENSG00000216490 "IFI30 lysosomal thiol reductase" P13284 19 18173162-18178117 "Predicted intracellular proteins, Predicted membrane proteins" Immunity Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 572.7;lymphoid tissue: 708.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 155.9;Kupffer cells: 205.4;Langerhans cells: 139.3;Macrophages: 426.2;monocytes: 144.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 9509.8;eosinophil: 3890.4;intermediate monocyte: 14243.6;myeloid DC: 5699.9;non-classical monocyte: 9865.9" "Group enriched" "Detected in all" 8 "dendritic cells: 5699.9;granulocytes: 3890.4;monocytes: 14243.6" "Cell line enhanced" "Detected in many" "Daudi: 655.7;RPMI-8226: 717.7;SK-BR-3: 457.4;U-266/84: 794.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026650 Enhanced Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 110000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA026650: AB_10602237" "unprognostic (4.66e-2)" "unprognostic (1.25e-4)" "unprognostic (2.35e-3)" "unprognostic (7.40e-2)" "unprognostic (1.76e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-3)" "unprognostic (2.40e-1)" "unprognostic (4.01e-2)" "unprognostic (9.19e-3)" "unprognostic (3.04e-1)" "unprognostic (1.19e-1)" "unprognostic (7.29e-11)" "unprognostic (3.50e-1)" "unprognostic (1.62e-2)" "unprognostic (3.39e-2)" "unprognostic (9.59e-3)" 132.4 121.0 18.4 708.3 20.8 283.8 58.6 20.3 104.5 40.8 48.7 129.0 197.3 22.2 26.9 38.7 57.3 109.6 31.2 18.0 23.3 80.3 148.2 572.7 370.7 32.0 24.9 14.8 61.3 75.0 27.9 128.8 40.5 31.6 148.0 2.6 66.3 22.0 12.6 55.0 153.6 165.0 26.8 385.3 112.2 16.0 69.4 91.9 54.2 9.0 221.0 215.7 19.6 49.8 115.5 59.2 0.4 37.9 11.2 19.9 102.6 11.8 17.2 34.6 91.8 132.3 193.1 655.7 96.6 39.7 175.2 85.1 69.9 30.1 3.7 182.5 55.2 8.1 98.1 188.9 111.8 20.1 46.9 70.4 60.4 59.8 19.7 4.4 2.0 23.8 96.8 394.8 16.6 217.3 9.9 2.5 21.2 380.6 68.7 65.8 4.5 717.7 101.1 3.7 5.3 8.0 200.5 457.4 11.3 7.4 31.6 8.8 4.2 55.2 34.2 120.7 12.0 14.6 794.7 368.5 154.1 133.5 8.5 106.9 9509.8 3890.4 40.8 14243.6 38.8 952.6 28.5 31.1 5699.9 708.1 19.7 24.3 2102.8 70.2 9865.9 173.2 41.5 11082.7 18.4 20.8 20.3 104.5 18.0 23.3 32.0 24.9 40.5 26.8 69.4 49.8 6.4 9.6 38.8 0.0 54.2 3.6 2.5 2.1 2.2 0.4 8.6 13.2 1.1 4.3 18.3 12.9 0.0 5.6 4.0 8.3 1.9 1.8 0.3 2.5 1.7 8.4 0.0 4.6 0.1 1.1 14.8 8.1 6.6 4.1 13.9 0.2 3.6 1.3 155.9 0.0 0.1 14.9 2.0 205.4 139.3 0.2 0.3 426.2 5.4 1.0 144.1 0.7 5.2 0.0 0.1 1.2 3.4 0.0 47.7 4.6 5.9 5.4 8.9 0.7 0.0 2.6 1.8 0.2 0.7 3.7 3.3 12.0 9.6 1.5 9.6 1.2 IGSF8 "CD316, CD81P3, EWI2, PGRL" ENSG00000162729 "Immunoglobulin superfamily member 8" Q969P0 1 160091340-160098943 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 155.3" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 177.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011917, HPA075970" Approved Supported Vesicles NA NA 280000 "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA011917: AB_1851536, HPA075970: " "unprognostic (4.08e-1)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.30e-2)" "unprognostic (9.31e-2)" "unprognostic (1.46e-1)" "unprognostic (1.20e-1)" "unprognostic (1.71e-1)" "unprognostic (1.01e-3)" "unprognostic (1.63e-2)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (2.31e-1)" "unprognostic (2.60e-2)" "unprognostic (2.35e-1)" "unprognostic (3.74e-3)" "unprognostic (1.75e-3)" 21.9 19.1 97.9 14.0 119.0 3.7 26.7 91.7 130.7 25.7 39.9 31.7 26.5 19.8 22.7 22.3 28.2 12.3 29.0 106.0 82.4 35.5 53.9 23.6 16.8 109.3 97.8 37.5 31.8 15.8 30.7 11.2 99.9 26.4 10.4 14.3 30.1 18.2 12.4 50.3 28.5 7.0 98.6 24.2 27.5 33.4 94.7 13.6 28.6 7.1 8.9 20.3 25.0 155.3 26.8 15.7 20.1 51.3 11.6 7.3 42.9 12.9 16.8 26.9 25.0 17.9 17.9 39.0 47.1 18.8 23.4 50.3 8.2 18.9 3.8 47.3 15.0 5.1 17.3 31.2 19.2 13.5 41.7 9.0 37.7 17.5 5.6 19.0 5.6 42.0 7.0 21.8 6.3 25.4 33.8 31.3 42.4 55.6 24.8 19.1 10.3 28.7 24.7 27.4 8.5 36.6 14.8 47.4 177.6 17.5 33.7 17.3 5.8 11.8 25.4 21.5 10.6 59.6 71.2 17.7 41.6 5.3 31.6 0.1 5.2 2.4 22.0 7.2 19.5 19.6 18.0 25.6 5.8 22.7 23.4 25.7 1.4 9.2 4.7 9.9 26.9 11.3 97.9 119.0 91.7 130.7 106.0 82.4 109.3 97.8 99.9 98.6 94.7 155.3 12.2 9.6 3.3 18.3 21.1 43.7 30.2 43.1 26.2 55.6 28.0 29.2 3.3 17.2 16.7 38.6 10.4 32.8 15.1 36.1 5.9 34.2 3.8 12.0 7.2 7.8 19.9 7.4 65.3 12.4 219.7 22.4 6.6 26.4 10.2 12.2 13.2 28.8 14.9 65.6 43.8 24.7 44.7 4.3 16.2 1.1 16.8 8.5 42.7 9.4 51.5 75.7 10.3 9.0 107.2 20.6 39.5 15.8 20.0 22.0 47.6 15.8 6.0 11.8 6.6 39.8 15.3 4.0 6.6 21.0 62.4 69.4 19.5 13.6 32.6 26.0 IL33 "C9orf26, DKFZp586H0523, DVS27, IL1F11, NF-HEV" ENSG00000137033 "Interleukin 33" O95760 9 6215786-6257983 "Predicted intracellular proteins, Predicted secreted proteins" Transcription Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 120.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 141.8;Fibroblasts: 87.5;Hepatic stellate cells: 499.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 53.6;U-2197: 162.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007057, HPA022899, HPA024426" Supported Supported Nucleoplasm,Vesicles "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "CAB007057: , HPA022899: , HPA024426: AB_1845820" "prognostic favorable (4.42e-4)" "unprognostic (8.36e-2)" "unprognostic (5.67e-3)" "unprognostic (7.67e-3)" "unprognostic (4.27e-1)" "unprognostic (1.63e-1)" "unprognostic (2.59e-3)" "unprognostic (2.66e-3)" "unprognostic (3.18e-1)" "unprognostic (2.05e-1)" "unprognostic (1.43e-1)" "unprognostic (8.08e-2)" "unprognostic (1.58e-3)" "unprognostic (4.70e-3)" "unprognostic (4.10e-2)" "unprognostic (2.64e-1)" "unprognostic (6.85e-3)" 38.7 16.7 9.2 44.6 9.3 0.2 27.2 7.0 12.1 56.2 6.4 24.8 8.8 50.0 15.9 24.5 25.9 33.4 40.9 8.5 10.8 5.0 36.7 53.0 47.1 7.8 8.3 5.0 3.4 3.7 5.7 61.1 7.1 30.0 19.4 2.0 18.9 31.5 6.1 44.0 15.6 50.8 8.3 20.5 33.6 5.8 10.8 13.1 12.6 13.8 43.0 120.7 21.2 8.6 0.0 0.0 0.0 0.0 0.3 1.4 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.1 16.9 0.3 0.0 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.7 0.3 0.4 53.6 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 162.9 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 9.3 7.0 12.1 8.5 10.8 7.8 8.3 7.1 8.3 10.8 8.6 63.5 6.4 7.2 39.5 1.0 24.2 17.0 73.9 27.3 0.0 9.4 4.1 5.8 4.3 77.8 0.0 0.0 0.0 0.1 2.2 0.0 3.0 0.5 12.4 7.1 141.8 10.7 8.0 0.2 7.9 0.0 87.5 48.4 20.6 1.3 0.0 499.4 5.0 0.1 0.0 0.1 0.2 2.0 20.8 10.2 1.6 20.5 1.7 1.8 1.0 0.0 9.5 0.0 0.5 0.1 12.1 0.2 12.4 0.2 5.2 0.0 0.0 62.1 0.1 0.0 65.5 11.5 0.0 0.4 3.3 48.4 0.1 1.2 0.1 1.1 4.9 IL37 "FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7" ENSG00000125571 "Interleukin 37" Q9NZH6 2 112912971-112918882 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 136.8" "Cell type enriched" "Detected in some" 26 "Ionocytes: 73.2" "Cancer enriched" "Detected in some" 6 "lung cancer: 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.7;PC-3: 5.9;RT4: 3.2" "HPA054371, HPA057950" Uncertain Supported Nucleoplasm,Vesicles "Secreted to blood" NA NA 76700 "Cluster 48: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "HPA054371: AB_2682465, HPA057950: AB_2683561" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" "unprognostic (3.71e-5)" "unprognostic (1.11e-1)" "unprognostic (2.58e-2)" "unprognostic (1.09e-2)" "unprognostic (1.28e-2)" "unprognostic (9.54e-2)" "unprognostic (8.26e-3)" "unprognostic (3.95e-2)" "unprognostic (1.66e-1)" "unprognostic (8.92e-2)" "unprognostic (1.35e-2)" 0.1 0.0 0.0 0.2 0.0 0.2 16.7 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.1 0.4 136.8 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.1 0.0 0.0 0.1 0.2 2.7 0.2 0.2 0.2 0.3 0.0 0.2 0.1 0.2 0.1 0.1 0.4 0.8 0.1 0.0 1.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.2 0.2 5.9 0.0 0.0 0.0 0.0 3.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 73.2 0.0 0.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 2.8 0.0 0.1 0.0 0.0 0.0 INHBE "activin, MGC4638" ENSG00000139269 "Inhibin subunit beta E" P58166 12 57452323-57459280 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "liver: 148.4" "Cell type enriched" "Detected in single" 43 "Hepatocytes: 35.0" "Cancer enriched" "Detected in some" 27 "liver cancer: 34.4" "Region enhanced" "Detected in some" "cerebellum: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 50.8;Karpas-707: 79.1;RH-30: 36.9;U-266/70: 263.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016843, CAB034017" Enhanced Supported Vesicles "Secreted to blood" NA NA 3500000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" Vesicles "CAB034017: AB_2233745, HPA016843: AB_1851796" "unprognostic (7.34e-2)" "unprognostic (6.73e-2)" "unprognostic (3.45e-1)" "unprognostic (4.69e-5)" "unprognostic (2.61e-1)" "unprognostic (2.50e-1)" "unprognostic (3.13e-1)" "unprognostic (1.24e-1)" "unprognostic (8.79e-3)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.66e-8)" "unprognostic (4.09e-3)" "unprognostic (1.56e-1)" "unprognostic (3.57e-2)" "unprognostic (7.52e-3)" 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.6 0.3 0.2 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.3 148.4 0.1 0.1 0.9 0.0 0.0 0.9 0.1 1.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 1.5 0.1 0.2 0.0 0.0 0.3 0.0 0.2 0.1 0.0 1.4 0.5 0.0 0.2 0.1 0.2 0.2 0.4 0.3 0.5 0.0 0.5 0.3 2.9 7.8 0.2 9.2 0.4 0.1 4.0 1.9 0.7 0.2 0.4 1.8 0.0 1.2 18.3 0.2 0.1 0.3 11.9 50.8 2.3 2.4 4.9 5.3 1.2 11.4 0.4 0.0 1.8 5.0 79.1 0.0 0.0 0.2 0.2 0.5 0.1 0.3 0.2 36.9 8.8 0.0 0.1 19.5 0.9 0.0 0.0 7.6 0.3 0.6 8.7 0.3 0.2 4.0 0.1 0.6 263.5 9.2 3.8 1.5 0.4 0.3 0.9 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.2 0.0 0.0 0.0 0.1 1.6 0.3 0.1 0.1 0.9 0.0 1.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 INPP5F "hSac2, KIAA0966, SAC2" ENSG00000198825 "Inositol polyphosphate-5-phosphatase F" Q9Y2H2 10 119726042-119829147 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 135.3" "Cell type enhanced" "Detected in all" "Excitatory neurons: 79.5;Inhibitory neurons: 130.5;Late spermatids: 88.6;Oligodendrocytes: 70.5" "Cancer enhanced" "Detected in all" "testis cancer: 27.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 91.4;SK-MEL-30: 149.0;SuSa: 181.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042605 Supported Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA042605: AB_10793886" "unprognostic (2.65e-2)" "unprognostic (3.23e-1)" "unprognostic (3.42e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-2)" "unprognostic (1.57e-3)" "unprognostic (2.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (6.46e-2)" "unprognostic (7.78e-2)" "unprognostic (1.02e-1)" "unprognostic (9.91e-2)" "unprognostic (2.96e-2)" "unprognostic (6.21e-2)" 9.9 16.8 53.8 9.9 49.4 4.7 7.6 45.3 63.9 15.7 10.1 15.5 4.6 15.4 22.8 9.3 8.3 6.9 5.9 50.6 135.3 10.5 3.2 9.1 10.7 71.2 57.3 12.3 6.7 7.4 57.1 10.9 75.0 10.9 8.0 32.9 10.8 10.0 11.0 13.7 9.5 13.2 50.3 7.5 8.6 14.8 62.7 7.0 10.5 3.8 13.0 9.2 12.5 55.2 13.5 8.2 91.4 14.3 6.9 10.6 8.5 18.4 9.3 8.4 8.4 12.0 15.2 8.3 7.6 19.7 10.6 14.4 7.9 9.8 11.9 6.0 10.3 6.5 3.9 11.0 13.5 4.4 19.0 9.7 8.6 14.2 13.5 15.7 23.2 6.1 5.7 13.8 20.8 7.0 5.5 15.7 9.2 9.9 12.0 7.0 18.8 2.3 12.5 5.3 6.5 70.2 19.8 7.2 149.0 181.5 4.3 3.4 19.6 9.9 12.2 11.0 17.5 15.2 7.7 4.5 11.0 12.8 32.3 0.9 3.4 1.3 1.0 3.0 1.3 6.7 2.2 1.3 6.2 9.1 2.2 1.1 0.8 3.4 3.6 1.4 5.3 1.9 53.8 49.4 45.3 63.9 50.6 135.3 71.2 57.3 75.0 50.3 62.7 55.2 7.8 6.4 4.8 52.5 21.5 9.1 11.7 7.5 10.2 24.2 6.9 9.5 5.4 1.5 7.8 12.9 16.7 9.3 7.9 15.1 11.7 3.6 58.7 4.3 18.3 8.6 1.2 5.2 79.5 4.5 10.6 7.9 5.1 6.9 2.5 9.7 4.2 3.5 9.9 42.1 130.5 5.6 10.2 6.0 27.8 88.6 5.3 13.1 19.6 34.7 16.3 21.7 6.2 52.8 70.5 6.8 6.6 3.8 4.7 8.2 6.5 24.7 4.0 21.6 6.6 7.8 13.8 22.4 41.0 13.1 10.4 13.3 7.7 19.3 6.5 13.1 IST1 "CHMP8, KIAA0174" ENSG00000182149 "IST1 factor associated with ESCRT-III" P53990 16 71845996-71931199 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041802, HPA054532" Approved Supported Vesicles NA NA 270000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041802: AB_10794491, HPA054532: AB_2682517" "unprognostic (2.15e-1)" "unprognostic (2.80e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-3)" "unprognostic (2.04e-2)" "unprognostic (3.13e-3)" "unprognostic (2.11e-2)" "unprognostic (4.49e-2)" "unprognostic (3.96e-2)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (1.02e-1)" "prognostic favorable (4.55e-4)" "unprognostic (1.64e-2)" "unprognostic (7.88e-3)" "unprognostic (8.43e-3)" "prognostic favorable (8.88e-4)" 47.7 44.1 43.2 38.8 49.7 81.0 50.5 46.2 50.6 49.0 43.9 68.3 52.4 55.9 42.4 50.5 61.4 46.8 50.4 42.9 45.3 68.7 37.9 50.0 64.3 47.2 47.6 60.0 46.9 90.4 57.2 60.1 47.1 45.7 62.9 32.4 52.0 45.8 64.1 52.5 52.0 60.8 45.5 50.6 52.5 47.4 46.1 62.2 59.4 80.8 81.6 53.0 44.3 53.8 57.0 81.9 113.3 73.2 110.7 77.9 95.7 70.0 87.1 95.2 98.9 90.1 77.1 80.5 84.2 81.2 67.7 83.8 112.0 74.2 120.4 53.7 54.1 68.1 46.8 146.9 83.8 66.9 91.9 92.7 100.8 85.5 81.6 94.8 120.6 74.8 94.5 28.7 99.5 94.9 87.4 55.6 129.7 92.7 50.6 135.7 62.0 99.1 78.5 81.8 85.0 63.3 77.2 40.3 63.9 138.2 73.7 82.2 60.7 71.8 70.9 44.5 55.9 75.0 145.5 226.7 60.7 59.2 88.6 234.9 195.1 243.5 158.7 185.4 172.6 179.1 150.6 166.9 180.1 178.5 159.6 150.1 300.0 193.7 185.1 124.9 244.9 293.9 43.2 49.7 46.2 50.6 42.9 45.3 47.2 47.6 47.1 45.5 46.1 53.8 59.7 48.1 51.8 39.8 57.1 70.1 41.2 49.8 39.9 29.2 69.1 50.0 43.9 60.1 48.1 46.0 25.0 56.7 68.4 130.6 35.2 47.1 18.4 50.0 52.8 55.4 75.4 30.7 35.5 41.7 44.3 48.1 42.3 70.1 61.4 55.1 61.1 40.8 53.4 21.9 41.6 76.3 46.8 81.1 73.8 22.5 41.0 57.2 42.7 38.4 75.9 22.2 51.5 34.2 59.7 58.1 88.4 47.8 45.2 51.5 82.2 52.4 56.2 30.3 59.2 45.3 44.4 52.4 57.3 34.4 70.0 65.7 51.8 31.3 57.6 66.4 JAG2 ENSG00000184916 "Jagged canonical Notch ligand 2" Q9Y219 14 105140982-105168824 "Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.1;Basal respiratory cells: 30.9;Basal squamous epithelial cells: 27.3;Breast myoepithelial cells: 26.4;Endothelial cells: 34.2;Horizontal cells: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 62.6;HBEC3-KT: 21.0;SCLC-21H: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025481, HPA030636, HPA050567" Approved Supported Vesicles,Cytosol NA NA 370000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Cytosol "CAB025481: , HPA030636: AB_10602607, HPA050567: AB_2681178" "unprognostic (6.74e-2)" "unprognostic (4.49e-2)" "unprognostic (4.28e-2)" "unprognostic (6.97e-3)" "unprognostic (3.50e-1)" "unprognostic (2.13e-2)" "unprognostic (1.01e-1)" "unprognostic (6.84e-2)" "unprognostic (1.18e-2)" "unprognostic (2.62e-1)" "unprognostic (1.67e-2)" "unprognostic (9.19e-2)" "unprognostic (8.47e-3)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.39e-1)" "unprognostic (2.17e-1)" 7.2 1.0 4.0 1.3 3.6 0.1 9.6 0.9 5.0 4.6 0.5 3.1 1.1 5.3 0.4 8.8 5.3 1.8 12.8 3.5 7.4 4.3 0.9 5.1 0.7 4.6 4.4 1.5 6.8 1.5 17.4 3.0 6.8 8.1 0.2 0.8 7.8 2.8 9.7 19.5 4.0 1.1 2.5 2.0 3.0 3.2 6.5 1.6 4.7 2.8 0.6 5.2 6.8 1.6 16.8 6.7 0.4 1.7 0.0 0.0 20.0 0.2 0.1 0.0 0.0 5.6 20.1 0.0 13.8 0.0 0.1 62.6 4.0 21.0 0.0 2.3 9.7 0.0 20.0 0.0 0.2 0.1 3.9 0.2 9.9 0.0 2.3 0.2 5.1 0.9 4.1 0.0 0.0 7.6 0.0 0.0 2.0 2.1 2.3 5.3 3.9 7.2 0.1 4.4 31.4 1.0 5.6 1.3 0.2 0.3 15.8 2.5 17.2 0.1 1.7 0.0 0.2 0.9 0.1 0.1 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 3.6 0.9 5.0 3.5 7.4 4.6 4.4 6.8 2.5 6.5 1.6 56.1 6.4 3.2 1.0 0.2 23.3 7.6 30.9 27.3 2.7 3.8 26.4 6.7 2.8 7.6 0.0 25.0 2.2 2.2 2.7 0.0 3.9 0.1 16.5 0.9 34.2 0.0 0.0 12.1 2.7 1.0 1.8 2.0 7.4 0.0 1.1 7.9 0.6 0.7 26.9 9.9 3.6 4.1 0.8 2.9 1.0 1.5 1.1 7.2 15.0 1.3 0.6 1.0 0.5 1.1 3.3 2.1 0.7 0.9 4.4 8.2 0.3 11.5 4.8 0.0 3.7 3.7 0.8 13.5 6.0 6.8 1.4 3.4 0.3 2.7 1.5 KCNH1 "eag, eag1, h-eag, hEAG, Kv10.1" ENSG00000143473 "Potassium voltage-gated channel subfamily H member 1" O95259 1 210676823-211134165 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 533.5;Inhibitory neurons: 261.0;Oligodendrocytes: 116.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 6.2;RH-30: 10.1;RPTEC TERT1: 6.0;SH-SY5Y: 12.9;SK-MEL-30: 12.9;T-47d: 9.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 34.0;cerebellum: 19.1;cerebral cortex: 23.9;hippocampal formation: 17.9;olfactory bulb: 8.9" "HPA014551, HPA019445, HPA076421" Enhanced Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA014551: AB_2669038, HPA019445: AB_1852118, HPA076421: " "unprognostic (9.12e-2)" "unprognostic (4.82e-3)" "unprognostic (2.63e-1)" "unprognostic (6.70e-2)" "unprognostic (3.56e-1)" "unprognostic (3.63e-2)" "unprognostic (1.73e-1)" "unprognostic (9.36e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-1)" "unprognostic (1.46e-2)" "unprognostic (2.77e-2)" "unprognostic (1.42e-3)" "unprognostic (1.17e-1)" "unprognostic (8.89e-2)" "unprognostic (1.36e-1)" "unprognostic (9.70e-2)" 0.2 0.9 6.8 0.4 9.2 0.0 0.2 9.5 17.9 0.7 2.7 0.5 0.3 0.4 0.2 0.1 0.6 0.2 0.0 11.2 5.3 0.1 0.1 0.0 0.0 4.8 4.4 0.1 0.2 0.0 0.7 0.3 4.0 0.5 0.3 0.3 0.1 0.1 0.2 0.1 0.8 0.2 4.0 0.0 0.5 1.5 4.9 0.2 0.1 0.6 0.0 0.2 0.4 8.3 0.0 2.1 0.4 0.1 0.0 0.1 0.1 1.0 0.2 2.1 2.4 0.0 0.0 0.0 0.0 1.4 2.4 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 6.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 10.1 0.0 6.0 0.0 0.4 12.9 2.4 0.2 12.9 1.7 9.2 0.0 0.0 1.6 0.2 2.0 1.2 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.8 9.2 9.5 17.9 11.2 5.3 4.8 4.4 4.0 4.0 4.9 8.3 0.2 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 11.2 0.2 2.8 0.1 0.0 0.0 533.5 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 261.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 7.5 0.0 0.0 0.0 19.1 116.6 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KDELR1 "ERD2, ERD2.1, HDEL" ENSG00000105438 "KDEL endoplasmic reticulum protein retention receptor 1" P24390 19 48382575-48391551 "Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 605.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 856.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017455 Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "Vesicles, Cytosol" "CAB017455: AB_10615208" "unprognostic (3.10e-2)" "unprognostic (4.17e-2)" "unprognostic (1.64e-1)" "unprognostic (1.87e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.49e-4)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.35e-2)" "unprognostic (2.26e-1)" "unprognostic (1.71e-1)" "unprognostic (1.51e-1)" "unprognostic (7.55e-2)" "unprognostic (4.97e-2)" "unprognostic (3.81e-1)" "unprognostic (2.74e-1)" "unprognostic (3.06e-1)" "unprognostic (1.68e-2)" 109.3 124.4 58.0 61.7 56.5 45.8 106.6 54.5 59.7 132.5 78.1 120.3 132.5 110.0 117.3 107.3 112.2 100.9 96.6 56.1 62.5 119.5 127.2 101.4 53.3 61.1 59.1 165.8 138.9 191.7 116.2 128.7 59.0 102.5 128.5 39.0 137.7 105.0 76.8 103.8 114.5 100.6 56.2 79.5 120.1 93.7 62.9 51.6 121.8 58.4 73.2 102.5 102.4 58.0 216.2 305.3 173.1 184.7 379.7 440.6 126.5 207.4 363.9 247.0 281.0 202.3 238.7 89.1 132.6 456.4 154.4 187.6 211.1 222.2 234.0 72.7 224.5 74.4 99.4 382.2 329.6 84.1 133.4 419.6 268.0 168.5 178.5 387.4 233.0 75.3 131.7 160.9 333.1 173.6 79.4 856.7 126.3 426.8 122.5 112.1 103.4 141.0 316.2 176.3 172.9 134.5 182.1 160.6 113.1 196.7 126.6 102.1 182.6 173.4 142.6 145.3 179.3 451.1 382.0 60.2 110.1 112.4 181.1 10.8 41.0 12.6 18.1 34.7 20.8 17.0 17.6 19.7 30.6 14.3 14.3 16.1 9.9 20.2 30.2 45.4 20.4 18.2 58.0 56.5 54.5 59.7 56.1 62.5 61.1 59.1 59.0 56.2 62.9 58.0 150.8 35.3 54.2 8.5 82.2 75.3 130.6 147.1 124.7 39.4 141.0 154.4 28.8 98.7 110.9 93.8 6.2 231.7 59.5 153.0 56.7 224.1 6.2 72.0 188.8 111.4 145.0 56.8 8.7 169.0 605.5 161.0 120.3 166.3 62.7 149.2 102.8 79.6 180.0 40.4 12.7 379.6 93.6 107.6 73.5 14.2 163.5 103.1 92.5 8.4 102.3 89.8 35.0 10.6 10.6 190.3 199.8 132.0 365.9 161.2 213.8 149.6 49.2 28.1 85.5 87.9 131.6 41.8 69.1 127.7 70.2 387.7 55.4 191.3 202.9 157.6 KLHL12 C3IP1 ENSG00000117153 "Kelch like family member 12" Q53G59 1 202891116-202928636 "Predicted intracellular proteins" "ER-Golgi transport, Transport, Ubl conjugation pathway, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 140.7;Late spermatids: 88.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071324 Supported "Vesicles,Centriolar satellite" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Vesicles, Centriolar satellite" "HPA071324: AB_2686389" "unprognostic (1.69e-2)" "unprognostic (2.84e-1)" "unprognostic (2.95e-2)" "unprognostic (1.97e-1)" "unprognostic (1.93e-1)" "unprognostic (4.86e-2)" "unprognostic (2.54e-3)" "unprognostic (3.35e-2)" "unprognostic (1.15e-2)" "unprognostic (9.11e-2)" "unprognostic (3.44e-1)" "unprognostic (1.58e-1)" "unprognostic (2.20e-3)" "unprognostic (6.22e-2)" "unprognostic (6.01e-2)" "unprognostic (3.32e-1)" "unprognostic (4.87e-2)" 13.3 15.8 26.4 14.6 26.8 18.8 17.3 24.7 27.8 13.8 23.9 19.4 14.5 14.9 22.7 15.8 18.4 12.3 20.4 27.5 29.8 21.8 16.2 15.0 19.0 24.6 26.5 17.7 16.3 21.2 15.2 15.6 27.6 19.3 23.4 24.6 13.7 13.6 14.3 13.5 14.8 17.3 24.6 17.1 16.0 44.8 28.5 20.4 19.8 18.3 22.4 14.2 13.1 26.4 20.4 24.5 30.2 34.3 46.2 34.2 35.6 24.1 28.0 29.7 27.0 23.3 33.0 57.8 18.5 27.7 29.8 25.8 40.5 33.8 32.3 29.9 17.6 20.1 19.5 23.6 33.4 42.3 31.7 33.0 43.0 25.7 56.1 23.5 26.8 56.9 51.5 36.7 41.3 28.0 35.6 20.4 43.4 25.8 18.3 36.5 52.8 37.0 26.1 25.7 22.5 25.8 29.9 27.6 33.2 54.7 49.2 29.4 22.0 29.0 20.2 7.1 21.7 26.4 22.5 48.0 28.6 29.9 28.3 7.5 10.1 15.6 6.9 12.3 10.2 7.1 6.9 8.3 10.5 6.7 7.3 7.9 10.1 8.3 13.2 6.1 11.1 9.2 26.4 26.8 24.7 27.8 27.5 29.8 24.6 26.5 27.6 24.6 28.5 26.4 7.0 6.4 11.5 12.7 13.3 5.4 9.4 8.9 6.2 11.2 8.5 5.7 16.6 12.8 9.2 16.5 12.5 11.9 9.3 17.6 23.5 12.1 140.7 8.6 7.8 7.8 10.8 15.8 14.9 8.9 12.1 9.3 5.6 7.4 3.8 15.0 8.6 7.8 17.2 5.0 19.3 13.2 6.1 15.9 5.6 88.1 8.4 12.9 5.4 14.0 16.8 11.3 10.3 11.1 18.6 11.4 10.1 8.2 9.3 8.7 11.6 15.9 8.2 10.2 6.6 6.9 7.6 26.0 44.9 9.2 6.7 11.1 11.5 9.5 12.5 7.2 KLHL22 "FLJ14360, KELCHL" ENSG00000099910 "Kelch like family member 22" Q53GT1 22 20441519-20495844 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 41.1;Excitatory neurons: 42.9;Inhibitory neurons: 51.1;Oligodendrocyte precursor cells: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040766 Supported "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA040766: AB_2732488" "unprognostic (4.15e-1)" "unprognostic (9.34e-3)" "unprognostic (5.37e-2)" "prognostic favorable (4.88e-6)" "unprognostic (1.17e-1)" "unprognostic (2.30e-3)" "unprognostic (1.00e-2)" "unprognostic (1.19e-3)" "unprognostic (2.20e-1)" "unprognostic (8.99e-2)" "prognostic favorable (3.85e-6)" "unprognostic (3.94e-2)" "prognostic favorable (1.34e-8)" "unprognostic (3.94e-2)" "unprognostic (3.10e-1)" "unprognostic (4.64e-2)" "unprognostic (1.08e-2)" 13.7 14.2 24.1 10.2 23.0 11.3 11.9 25.9 25.1 20.5 18.2 16.6 7.7 20.4 17.2 8.0 17.9 13.6 14.2 22.9 21.4 15.6 10.8 11.8 17.6 18.0 18.1 22.3 16.5 22.9 19.6 11.6 18.7 18.7 10.6 15.3 14.0 18.0 22.1 11.7 10.4 21.7 14.8 15.6 12.2 10.2 23.1 8.0 20.8 18.0 20.7 13.4 10.9 21.2 17.1 16.5 37.5 29.9 30.6 35.5 9.0 21.4 37.6 21.0 23.6 8.2 6.4 11.9 7.0 37.3 16.9 21.3 25.6 9.2 18.1 25.9 15.1 12.6 17.4 8.3 30.6 2.6 11.7 26.9 14.2 19.3 12.4 26.8 31.3 9.1 32.7 11.4 20.7 25.9 2.5 15.6 6.3 14.1 11.4 23.5 13.8 0.5 12.3 19.9 19.9 20.3 23.0 16.9 15.8 12.3 15.7 9.3 14.2 25.1 12.2 17.5 8.9 6.4 7.4 7.9 13.5 11.1 16.6 8.9 4.6 19.3 8.1 6.3 6.4 8.3 10.2 7.5 15.5 6.2 7.7 8.3 10.6 16.6 8.3 5.6 19.2 6.5 24.1 23.0 25.9 25.1 22.9 21.4 18.0 18.1 18.7 14.8 23.1 21.2 4.6 0.0 3.7 41.1 8.2 1.7 2.8 8.4 4.0 11.7 4.3 5.2 4.8 10.0 5.3 9.2 4.2 17.9 5.2 2.9 3.9 8.4 0.8 3.2 7.1 4.8 3.0 1.3 42.9 2.6 6.6 9.2 5.1 3.9 5.1 14.2 4.2 6.3 7.9 13.5 51.1 5.2 12.2 5.7 4.9 1.8 12.2 4.8 1.8 16.9 4.2 13.9 7.2 41.2 26.8 5.6 3.5 19.9 5.4 3.9 3.0 10.9 4.3 6.7 6.6 4.7 5.3 17.3 15.4 2.8 1.4 13.4 7.8 17.7 3.8 1.8 LAMP2 CD107b ENSG00000005893 "Lysosomal associated membrane protein 2" P13473 X 120426148-120469365 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Autophagy "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 507.2;Syncytiotrophoblasts: 402.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 556.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 556.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005272, HPA029100" Supported Supported Vesicles NA NA 520000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB005272: AB_647855, HPA029100: AB_10795022" "unprognostic (2.99e-3)" "unprognostic (5.26e-2)" "unprognostic (2.66e-3)" "unprognostic (1.74e-1)" "unprognostic (3.10e-1)" "unprognostic (2.50e-2)" "unprognostic (4.84e-1)" "unprognostic (1.56e-1)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (9.73e-2)" "unprognostic (1.11e-2)" "unprognostic (2.50e-2)" "unprognostic (2.85e-1)" "unprognostic (6.78e-2)" "unprognostic (2.66e-1)" "unprognostic (5.53e-3)" 54.2 68.7 80.3 38.3 144.2 62.8 56.3 109.1 135.5 64.9 52.7 39.2 44.3 44.3 55.1 79.4 44.1 69.6 45.3 81.6 101.8 85.5 129.9 54.2 34.1 113.0 112.6 49.1 57.8 64.2 32.2 47.9 120.6 62.2 35.0 32.6 102.1 55.1 111.6 67.2 42.4 42.8 100.5 39.5 51.8 26.2 100.9 59.3 61.7 67.4 36.6 43.4 63.3 211.7 53.8 47.5 40.1 49.7 367.0 140.9 91.5 79.3 130.4 77.1 134.4 42.7 90.3 47.9 73.1 132.7 236.2 84.9 56.7 67.2 125.5 43.6 37.2 35.8 46.4 54.3 148.1 158.9 73.2 151.5 114.8 108.1 75.1 188.6 107.5 32.5 42.1 122.9 117.2 79.3 45.3 80.2 29.0 63.7 42.6 35.1 65.3 73.1 102.3 36.9 14.0 22.6 99.7 93.0 196.5 57.4 64.7 173.0 122.5 114.1 58.7 176.2 261.5 68.5 78.6 30.2 131.4 182.4 284.4 30.6 114.9 224.1 27.1 97.1 20.6 17.1 24.3 24.5 64.2 22.5 23.4 21.8 556.6 31.8 96.2 33.4 33.4 66.3 80.3 144.2 109.1 135.5 81.6 101.8 113.0 112.6 120.6 100.5 100.9 211.7 75.7 73.7 53.8 52.2 29.8 100.9 92.5 262.7 64.9 17.6 74.0 58.3 37.3 173.0 155.3 66.2 14.6 163.7 44.3 52.1 39.2 217.7 3.3 103.4 74.1 69.9 36.6 14.1 32.4 70.6 128.3 113.7 38.7 168.1 17.7 46.7 87.8 176.8 208.0 18.5 40.7 32.6 134.3 133.1 80.4 8.6 113.7 135.5 131.6 33.7 132.7 116.3 50.4 57.3 507.2 62.5 54.4 109.9 66.6 100.8 97.5 154.7 75.6 11.5 39.5 176.8 61.7 6.4 13.7 78.8 136.2 402.4 34.5 71.0 34.8 92.9 LAMTOR1 "C11orf59, FLJ20625, p18, p27RF-Rho, Pdro, Ragulator1" ENSG00000149357 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1" Q6IAA8 11 72085895-72103297 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002997 Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 160000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus" "Vesicles, Plasma membrane" "HPA002997: AB_1845531" "unprognostic (7.32e-2)" "unprognostic (1.79e-1)" "unprognostic (3.94e-2)" "unprognostic (3.77e-2)" "unprognostic (2.30e-1)" "unprognostic (2.71e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.00e-1)" "unprognostic (2.18e-1)" "unprognostic (1.94e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-3)" "unprognostic (1.78e-3)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.04e-1)" 100.7 143.8 171.2 69.1 177.8 118.6 96.2 173.2 180.4 87.0 162.1 88.6 67.5 86.5 90.0 114.1 74.9 65.8 131.9 163.5 169.5 129.5 114.2 91.3 80.6 177.4 177.2 81.5 85.6 87.0 92.0 67.4 174.9 102.4 76.5 46.6 85.8 71.7 126.4 89.9 82.5 73.7 175.4 130.9 96.6 41.2 176.1 75.4 112.3 109.3 79.4 88.5 77.9 172.5 94.2 181.0 97.3 132.0 224.7 152.3 97.6 129.0 201.6 206.2 151.7 230.9 139.7 93.1 162.3 216.9 214.2 138.1 171.1 260.1 155.8 117.8 99.3 245.6 108.5 156.5 291.4 97.2 147.7 252.3 199.2 224.4 224.0 116.4 173.1 102.5 104.1 96.0 211.4 295.6 86.2 146.1 93.9 291.8 194.9 73.7 178.9 78.8 246.8 195.1 65.7 103.3 127.6 127.5 343.7 106.4 192.6 93.2 125.3 137.5 98.0 323.8 93.0 111.6 139.0 80.4 81.8 81.8 113.0 113.4 414.3 274.1 80.6 228.8 77.7 132.1 75.6 81.1 332.6 146.2 63.4 77.9 229.5 122.8 180.6 197.1 98.8 397.5 171.2 177.8 173.2 180.4 163.5 169.5 177.4 177.2 174.9 175.4 176.1 172.5 132.6 44.8 71.6 9.1 109.7 55.7 161.7 271.1 117.8 58.5 159.9 195.7 66.4 121.5 120.2 128.8 12.5 266.5 110.7 235.4 295.4 276.4 12.4 61.2 98.9 134.9 116.4 133.5 9.8 340.2 300.1 111.6 71.4 85.2 97.7 71.5 142.1 86.9 468.0 77.4 12.9 140.2 170.9 248.5 111.6 19.2 107.8 311.5 113.8 8.4 413.6 223.7 177.1 10.1 24.2 307.3 202.6 102.7 87.9 193.4 230.3 370.9 61.0 56.1 111.7 102.5 116.3 58.7 103.3 126.1 55.4 282.0 89.4 178.5 170.8 157.2 LAMTOR4 C7orf59 ENSG00000188186 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4" Q0VGL1 7 100148907-100155944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 3294.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020998 Enhanced Supported Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA020998: AB_1845762" "prognostic favorable (2.48e-4)" "prognostic favorable (6.08e-4)" "unprognostic (1.29e-2)" "unprognostic (1.14e-1)" "unprognostic (8.21e-3)" "unprognostic (6.11e-2)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (6.17e-2)" "unprognostic (1.57e-1)" "unprognostic (2.42e-3)" "unprognostic (8.83e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-1)" "unprognostic (2.68e-1)" "unprognostic (2.45e-1)" "unprognostic (1.68e-2)" 145.5 144.7 207.2 92.8 215.4 194.6 143.4 221.1 260.4 148.0 204.4 180.6 89.4 116.7 65.9 117.5 123.1 97.7 167.4 205.7 212.3 188.5 139.1 128.0 159.0 222.1 211.3 142.7 124.2 126.7 162.7 68.1 213.3 160.8 105.8 39.9 116.8 76.2 137.5 478.7 151.0 69.0 217.6 251.9 162.2 86.6 215.8 104.8 133.8 106.0 85.5 145.8 126.7 224.1 105.9 250.9 130.2 165.4 135.2 154.9 105.7 62.1 151.0 113.1 138.9 116.9 165.7 169.1 204.7 94.2 205.7 108.9 124.0 160.0 48.1 172.4 353.2 135.2 245.0 205.4 127.4 106.4 187.1 187.3 155.4 118.5 145.6 125.7 174.9 155.3 129.9 264.4 156.1 501.0 104.0 424.7 138.7 291.1 199.9 107.4 107.1 302.8 129.1 126.9 91.6 169.0 114.3 265.8 211.3 99.0 107.1 207.0 118.3 107.1 158.6 223.7 101.7 159.1 231.2 324.2 171.0 293.5 155.9 1033.3 843.2 3121.0 299.6 795.1 251.1 541.8 377.5 312.8 570.0 475.4 381.8 307.2 3294.2 310.1 756.2 482.6 453.0 893.6 207.2 215.4 221.1 260.4 205.7 212.3 222.1 211.3 213.3 217.6 215.8 224.1 181.8 93.0 150.7 18.9 195.8 274.9 194.0 282.0 167.9 65.3 240.8 277.2 176.6 143.0 172.9 218.8 12.5 258.4 199.9 819.7 534.1 167.3 40.0 152.9 125.8 186.7 299.3 99.3 12.0 326.2 196.5 175.6 146.3 131.4 183.2 120.9 239.1 246.3 531.1 58.9 13.6 423.9 252.3 497.4 351.7 46.6 146.3 365.2 434.0 13.1 411.0 229.9 298.6 11.6 26.2 204.2 867.4 120.4 133.0 169.5 511.6 557.5 194.8 67.0 144.7 142.1 196.9 88.1 101.2 151.3 662.9 201.4 195.9 150.8 511.8 219.0 LDLRAD4 C18orf1 ENSG00000168675 "Low density lipoprotein receptor class A domain containing 4" O15165 18 13217498-13652755 "Predicted intracellular proteins, Predicted membrane proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.2;lymphoid tissue: 49.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 338.9;Inhibitory neurons: 308.5;Late spermatids: 231.5;Microglial cells: 429.1;Oligodendrocyte precursor cells: 318.7;Oligodendrocytes: 284.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 35.3;JURKAT: 37.4;MOLT-4: 131.3;REH: 31.6;U-698: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047633, HPA065246" Approved Supported Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA047633: , HPA065246: AB_2685444" "unprognostic (2.52e-1)" "unprognostic (4.31e-3)" "unprognostic (5.30e-2)" "unprognostic (1.23e-1)" "unprognostic (1.64e-1)" "unprognostic (3.94e-3)" "unprognostic (9.73e-2)" "unprognostic (2.26e-2)" "unprognostic (2.21e-2)" "unprognostic (2.92e-2)" "unprognostic (2.30e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (4.58e-4)" "unprognostic (2.51e-2)" "unprognostic (4.38e-2)" "unprognostic (6.58e-2)" "unprognostic (8.18e-2)" 6.5 4.3 13.9 7.3 38.0 9.7 6.3 34.6 25.9 7.8 37.4 5.8 6.1 12.4 0.9 3.9 11.3 4.6 16.6 10.7 16.4 4.0 10.3 4.6 6.5 46.1 33.2 2.3 3.3 2.9 6.9 6.2 38.6 8.6 2.1 7.0 3.0 5.3 15.4 4.2 7.2 5.7 27.3 5.6 5.0 9.2 48.2 49.3 4.4 9.5 3.8 5.3 5.3 39.6 0.2 0.3 1.4 0.8 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.1 0.1 2.7 1.6 0.8 0.4 0.0 0.0 0.0 17.1 1.7 35.3 7.0 1.2 0.0 1.7 0.9 0.0 0.0 0.0 0.0 0.0 0.4 37.4 0.4 0.7 0.0 2.6 131.3 1.1 2.9 0.3 8.9 31.6 0.1 1.2 0.0 1.1 2.4 3.9 0.5 2.2 0.0 1.9 3.8 4.7 2.4 1.3 11.5 0.2 1.9 5.6 0.4 26.1 0.0 6.9 6.4 12.8 7.0 2.1 6.5 7.7 5.7 5.2 5.8 5.6 3.9 4.4 8.2 7.6 12.1 9.1 8.5 5.9 3.4 4.5 13.9 38.0 34.6 25.9 10.7 16.4 46.1 33.2 38.6 27.3 48.2 39.6 19.4 3.2 4.7 143.3 79.2 10.5 2.7 0.8 0.0 5.4 26.0 16.9 18.4 0.0 5.0 1.8 70.9 0.6 21.0 6.8 1.9 5.1 135.2 16.3 22.0 16.6 58.7 7.6 338.9 3.6 0.7 16.5 13.3 7.8 23.5 7.6 25.0 24.4 21.1 0.0 308.5 9.1 2.0 27.4 160.5 231.5 11.1 56.2 14.2 429.1 13.6 4.7 3.1 318.7 284.9 0.7 2.6 24.5 11.7 13.5 15.6 2.3 13.7 18.7 6.6 2.3 9.7 5.4 4.9 0.4 7.7 1.6 66.0 0.2 8.8 3.2 LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 398.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 515.0;Kupffer cells: 714.8;Macrophages: 303.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 167.3;intermediate monocyte: 355.1;myeloid DC: 123.6;non-classical monocyte: 198.5" "Group enriched" "Detected in all" 6 "dendritic cells: 123.6;monocytes: 355.1" "Cell line enhanced" "Detected in many" "A-431: 354.4;AN3-CA: 367.8;ASC TERT1: 450.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Intracellular and membrane" NA NA 280000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "CAB034892: AB_784329, HPA057052: AB_2683322" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (7.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-3)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (5.71e-2)" 76.0 46.3 43.5 66.7 65.2 39.8 47.8 64.1 74.4 54.0 39.0 67.7 167.6 38.8 21.7 28.6 37.8 83.5 24.2 43.5 53.1 44.9 218.9 169.5 159.3 74.7 55.5 32.7 21.4 68.9 12.7 79.1 82.2 30.7 72.0 12.6 22.5 33.8 11.8 18.7 227.5 47.7 65.4 398.4 34.3 13.4 57.0 44.5 31.6 22.5 45.5 58.4 19.3 115.5 354.4 49.4 30.7 367.8 343.5 450.8 10.0 171.4 194.8 65.5 121.5 18.6 176.6 63.9 34.0 264.4 73.7 338.7 13.8 92.8 53.6 86.1 34.7 25.1 19.1 81.5 87.6 48.8 48.9 190.4 69.2 72.9 40.6 88.2 14.9 45.4 0.3 108.5 58.3 28.2 45.7 34.6 22.7 62.4 60.0 26.4 39.0 60.5 69.2 50.9 10.5 21.8 41.4 49.9 133.9 20.4 64.4 65.8 26.2 58.8 15.5 132.1 44.6 60.0 65.7 25.8 71.4 112.9 82.1 4.2 167.3 16.9 40.0 355.1 40.6 31.9 35.8 38.8 123.6 33.4 36.7 40.4 7.1 29.8 198.5 25.0 38.2 159.6 43.5 65.2 64.1 74.4 43.5 53.1 74.7 55.5 82.2 65.4 57.0 115.5 75.5 41.7 33.8 11.1 35.9 17.7 30.3 58.1 25.6 5.4 16.1 14.1 9.6 45.8 31.9 33.1 0.0 34.8 31.4 2.8 21.5 35.1 6.8 11.4 20.4 56.7 21.8 27.4 34.4 36.2 32.9 34.6 21.4 15.5 28.5 10.8 54.7 66.7 515.0 16.8 15.1 8.9 40.7 714.8 69.0 2.7 11.5 303.1 48.0 30.0 71.7 33.1 29.9 15.1 143.0 19.3 12.0 21.8 15.4 11.3 161.0 14.0 28.8 2.2 6.6 19.7 21.0 5.1 13.8 31.9 12.5 20.0 33.1 17.6 9.1 24.0 LITAF "FLJ38636, PIG7, SIMPLE, TP53I7" ENSG00000189067 "Lipopolysaccharide induced TNF factor" Q99732 16 11547722-11636381 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 701.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 2578.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 2578.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006960 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Golgi apparatus, Vesicles" "HPA006960: AB_1079254" "unprognostic (2.26e-1)" "unprognostic (4.96e-2)" "unprognostic (2.32e-3)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.02e-4)" "unprognostic (4.07e-2)" "unprognostic (8.75e-3)" "unprognostic (3.60e-1)" "unprognostic (6.15e-3)" "unprognostic (1.04e-1)" "unprognostic (4.61e-2)" "unprognostic (5.01e-1)" "unprognostic (1.85e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (3.57e-2)" "unprognostic (1.60e-1)" 139.3 43.7 53.5 165.8 81.9 207.0 95.5 79.6 70.0 121.2 70.5 121.1 46.3 100.5 77.8 62.7 108.2 114.1 63.9 52.2 63.0 182.3 107.7 192.1 112.3 94.0 79.4 67.6 64.6 56.5 39.0 71.3 92.7 105.9 116.1 63.9 116.4 83.4 36.3 71.6 57.9 93.5 77.3 119.6 70.7 10.6 77.6 68.6 116.8 37.6 123.7 214.1 83.1 109.4 79.2 157.8 89.4 43.8 13.9 11.0 90.7 100.2 309.0 93.6 139.1 62.6 206.3 39.9 126.8 86.1 108.7 95.5 40.1 186.4 88.4 304.2 45.8 2.8 117.1 310.3 212.9 12.5 12.9 35.0 320.8 79.6 210.7 84.4 0.3 2.7 25.3 149.5 1.5 75.8 1.8 183.3 146.4 104.0 0.6 12.1 19.6 228.2 79.0 110.4 22.2 68.0 172.9 219.4 183.9 136.3 122.5 66.7 0.8 38.7 65.3 23.0 24.2 59.2 140.6 100.5 45.1 95.8 225.5 508.8 149.5 284.0 459.6 130.2 277.2 174.0 284.0 412.7 178.0 173.9 318.9 381.4 2578.1 274.5 81.9 220.1 350.3 584.9 53.5 81.9 79.6 70.0 52.2 63.0 94.0 79.4 92.7 77.3 77.6 109.4 297.5 44.8 70.0 7.5 176.7 157.4 336.2 365.4 68.3 2.2 180.5 157.6 48.8 148.7 222.2 163.7 0.0 56.4 505.5 305.4 485.2 245.8 2.3 112.2 151.9 76.3 17.5 18.3 1.1 72.9 471.9 156.7 39.8 108.1 214.9 1.1 94.2 52.9 227.8 0.0 1.6 153.1 175.0 156.9 701.0 11.3 56.2 422.0 156.5 7.5 391.8 232.7 433.5 11.6 59.5 123.3 236.1 68.4 186.3 239.8 23.3 104.3 150.3 5.4 52.6 89.6 176.1 0.2 5.4 37.1 132.1 37.1 278.7 16.6 88.9 368.6 LMAN1 "ERGIC-53, ERGIC53, F5F8D, FMFD1, gp58, MCFD1, MR60" ENSG00000074695 "Lectin, mannose binding 1" P49257 18 59327823-59359265 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 502.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002320, CAB037163" Supported Supported "Endoplasmic reticulum,Vesicles" NA NA 18000000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Endoplasmic reticulum" "CAB037163: AB_532237, HPA002320: AB_1079256" "unprognostic (5.64e-2)" "unprognostic (8.96e-3)" "unprognostic (4.20e-3)" "unprognostic (1.61e-1)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (1.65e-1)" "unprognostic (5.40e-3)" "unprognostic (1.16e-1)" "unprognostic (2.03e-1)" "unprognostic (2.40e-2)" "unprognostic (1.06e-1)" "unprognostic (5.79e-2)" "unprognostic (4.28e-2)" "unprognostic (5.37e-3)" "unprognostic (7.05e-2)" "unprognostic (3.71e-3)" 36.0 43.3 14.8 39.4 16.4 21.7 43.8 16.9 19.4 66.0 20.1 34.1 45.7 46.1 52.9 31.1 48.8 31.9 42.6 13.8 19.4 64.5 181.1 33.6 28.4 17.1 16.0 43.3 53.1 74.3 32.7 54.8 17.4 58.4 39.3 40.0 69.0 43.7 33.3 20.3 49.1 37.7 16.2 27.4 59.3 21.2 16.0 32.1 86.5 41.1 34.8 40.1 21.2 20.4 90.6 52.7 55.1 46.4 125.6 215.6 110.7 159.6 227.9 105.7 140.5 52.7 85.2 16.0 110.7 191.0 75.7 108.1 79.0 90.5 191.0 61.7 50.4 52.5 65.4 109.5 148.9 183.6 77.0 144.7 106.8 102.5 208.1 198.1 108.1 54.3 89.7 173.6 104.2 24.5 53.5 37.9 37.8 45.8 64.5 60.0 100.1 176.0 58.9 67.6 37.5 40.9 80.6 78.0 91.6 76.8 57.8 70.8 89.8 170.5 59.9 55.2 94.0 131.6 71.3 76.2 179.1 96.0 142.6 6.0 2.5 0.7 7.3 3.7 10.0 7.1 7.9 7.7 3.5 5.1 7.5 7.7 0.3 10.0 2.1 8.8 9.6 4.0 14.8 16.4 16.9 19.4 13.8 19.4 17.1 16.0 17.4 16.2 16.0 20.4 120.0 102.5 97.1 15.0 104.0 69.8 120.3 213.5 84.8 39.2 104.5 97.2 134.6 71.4 171.2 80.9 106.3 149.3 86.7 32.8 21.5 130.6 28.1 117.5 203.7 97.7 51.6 49.6 17.2 84.6 304.8 162.4 106.0 200.7 33.6 96.9 75.0 394.0 80.2 58.9 22.1 181.4 107.8 41.9 40.1 10.3 110.6 52.5 67.6 22.5 53.5 76.8 54.6 20.1 33.5 71.6 45.5 85.4 502.1 214.1 95.5 75.6 164.7 66.7 65.7 95.4 142.3 47.2 65.1 80.7 57.0 231.2 69.5 149.6 89.7 129.5 LMBRD1 "bA810I22.1, C6orf209, cblF, FLJ11240" ENSG00000168216 "LMBR1 domain containing 1" Q9NUN5 6 69672757-69867236 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Endocytosis, Gastrulation, Host-virus interaction, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 21.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016491, HPA019547" Uncertain Supported Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 59: Non-specific - Transcription" Vesicles "HPA016491: , HPA019547: AB_2281256" "unprognostic (1.44e-1)" "unprognostic (3.84e-2)" "unprognostic (7.67e-2)" "unprognostic (7.64e-2)" "unprognostic (2.41e-1)" "unprognostic (5.37e-2)" "unprognostic (2.26e-1)" "unprognostic (4.39e-2)" "unprognostic (2.19e-1)" "unprognostic (1.97e-1)" "unprognostic (2.22e-1)" "unprognostic (1.47e-1)" "prognostic favorable (1.07e-7)" "unprognostic (7.99e-2)" "unprognostic (1.67e-1)" "unprognostic (2.60e-2)" "unprognostic (2.68e-2)" 33.3 49.4 10.3 11.5 10.8 4.2 31.4 20.7 17.0 28.9 13.3 26.4 13.5 22.5 27.7 25.7 26.3 16.0 27.7 11.1 11.5 53.0 42.9 27.9 12.1 13.6 11.9 34.5 36.5 31.7 26.5 17.2 12.3 19.1 20.5 10.7 33.2 20.0 28.8 28.1 28.6 12.7 11.4 21.8 29.6 10.4 10.2 9.1 35.1 13.1 16.8 30.1 29.4 16.1 3.8 3.8 6.0 10.2 16.5 23.7 17.9 2.2 7.1 2.6 5.6 4.8 8.2 6.5 9.2 8.8 5.8 7.5 3.8 9.8 2.4 16.3 11.9 6.2 4.9 7.8 13.7 3.4 8.7 7.6 9.6 0.8 5.7 19.1 7.4 5.5 9.4 6.1 6.0 8.1 2.5 4.7 4.6 8.5 4.8 0.3 15.4 37.8 17.0 13.8 5.5 8.5 0.9 7.0 13.3 3.0 4.6 25.3 1.1 3.9 4.6 4.3 2.8 8.8 5.5 2.8 2.3 4.0 12.3 6.5 2.2 3.9 2.0 2.5 2.5 12.1 2.9 1.9 1.7 21.0 3.1 2.3 11.4 2.6 4.8 2.2 3.7 2.1 10.3 10.8 20.7 17.0 11.1 11.5 13.6 11.9 12.3 11.4 10.2 16.1 49.7 64.1 38.3 82.3 93.4 29.1 41.9 45.2 71.2 73.7 39.2 25.4 40.6 50.1 56.0 58.8 110.5 69.6 36.2 79.0 19.6 49.0 28.8 48.3 22.7 41.1 18.7 18.5 119.2 49.6 59.2 56.1 36.7 61.7 40.5 15.7 44.6 60.5 42.1 55.5 144.6 37.6 44.7 66.9 36.3 9.3 35.4 52.0 32.0 79.6 49.3 56.3 28.8 122.2 156.6 42.0 51.0 33.8 82.7 19.6 78.7 64.1 65.5 90.8 26.3 36.4 33.9 22.5 16.9 43.4 38.1 77.4 43.2 26.9 31.7 34.2 LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967259 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 937.4;heart muscle: 407.8" "Cell type enhanced" "Detected in many" "Adipocytes: 453.0;Cardiomyocytes: 489.0;Granulosa cells: 495.2;Horizontal cells: 206.9;Sertoli cells: 236.7" "Cancer enhanced" "Detected in all" "glioma: 39.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 6 "monocytes: 4.2" "Cell line enriched" "Detected in some" 5 "AF22: 391.6" "Region enhanced" "Detected in many" "basal ganglia: 45.3" "Group enriched" "Detected in all" 5 "basal ganglia: 79.2;spinal cord: 59.3" HPA048749 Supported Vesicles "Secreted to blood" NA NA 4200000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA048749: AB_2680511" "unprognostic (5.52e-2)" "unprognostic (3.16e-1)" "unprognostic (6.41e-2)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-4)" "unprognostic (1.05e-1)" "unprognostic (6.78e-2)" "unprognostic (8.20e-2)" "unprognostic (2.54e-2)" "unprognostic (5.28e-1)" "unprognostic (1.18e-1)" "unprognostic (4.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.07e-4)" 937.4 15.9 6.8 9.1 53.2 0.9 255.4 20.3 12.2 2.7 8.9 12.0 1.5 3.7 0.5 2.8 2.7 8.6 407.8 10.7 9.5 19.1 0.7 62.1 8.5 7.4 7.7 10.6 6.3 181.5 4.1 14.7 7.9 3.8 5.8 11.1 24.4 64.7 86.4 8.3 13.3 4.1 5.5 1.6 8.4 1.0 11.5 4.3 10.6 127.3 2.8 6.1 4.7 8.8 0.0 0.0 391.6 0.1 8.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.8 0.0 0.0 0.1 0.3 0.0 71.5 0.0 0.2 8.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.1 0.7 9.6 0.0 0.0 0.0 0.0 68.4 0.0 0.0 8.4 0.2 0.0 0.0 0.1 13.5 0.0 1.8 0.0 0.0 8.1 0.0 3.5 0.0 0.1 0.1 0.1 0.1 32.6 0.0 0.9 0.7 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 6.8 53.2 20.3 12.2 10.7 9.5 7.4 7.7 7.9 5.5 11.5 8.8 453.0 12.8 104.9 1.0 0.4 1.5 0.1 0.0 0.6 2.8 114.7 5.7 489.0 0.0 0.6 0.0 2.1 0.4 0.9 0.1 15.6 0.0 0.8 0.2 2.5 56.1 0.0 0.0 1.9 0.0 0.7 13.6 0.0 0.3 6.3 495.2 2.9 0.0 108.5 206.9 0.4 1.0 0.0 14.8 4.2 1.3 1.2 38.2 14.2 1.9 2.0 2.3 0.0 9.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.4 2.9 2.7 236.7 91.4 68.1 0.4 0.2 0.2 0.6 0.4 2.3 4.3 2.8 0.1 LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lung: 52.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 502.2;Excitatory neurons: 92.0;monocytes: 133.1;Oligodendrocyte precursor cells: 256.9" "Cancer enhanced" "Detected in many" "renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.2" "Lineage enriched" "Detected in many" 8 "granulocytes: 58.2" "Cell line enhanced" "Detected in some" "A549: 4.6;ASC TERT1: 5.6;BJ hTERT+: 3.2;RPTEC TERT1: 7.8;T-47d: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Supported Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" Vesicles "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favorable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" 4.8 3.1 1.1 10.1 1.9 9.0 2.6 0.9 2.1 5.1 1.2 4.3 0.6 4.8 1.9 7.0 4.1 6.2 3.9 1.3 1.1 10.9 5.6 52.4 6.8 1.7 1.1 5.4 3.6 8.4 2.1 1.2 1.4 2.6 1.8 1.5 3.5 2.0 5.5 2.1 3.6 4.0 1.1 10.8 2.1 0.8 1.2 2.5 2.9 7.9 5.4 4.5 5.5 1.9 0.0 4.6 0.0 0.0 2.3 5.6 0.0 1.3 3.2 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.0 0.6 0.4 0.0 2.1 0.4 0.0 0.0 2.5 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.3 0.0 0.5 2.7 0.1 3.1 1.5 1.0 0.4 0.5 0.6 0.4 0.0 0.0 0.0 1.3 0.0 1.7 0.0 7.2 2.2 0.0 5.2 0.0 1.8 0.0 0.0 2.1 1.7 0.0 0.0 58.2 0.0 6.9 0.3 0.0 1.3 1.1 1.9 0.9 2.1 1.3 1.1 1.7 1.1 1.4 1.1 1.2 1.9 7.4 32.1 502.2 17.3 29.9 2.4 1.8 0.4 2.8 8.6 1.3 1.4 7.8 5.7 17.3 27.6 0.0 0.0 1.9 0.0 1.9 1.3 0.5 0.4 2.6 7.0 0.0 2.1 92.0 2.7 0.1 16.1 0.5 0.4 13.9 2.7 13.2 8.2 4.6 47.1 28.0 0.0 0.0 55.8 8.7 1.2 19.0 52.2 12.4 73.1 133.1 8.6 3.1 256.9 3.1 0.8 1.1 12.0 2.8 0.6 0.0 22.5 3.4 1.0 0.0 22.5 4.8 0.3 1.0 12.6 3.1 0.4 3.4 11.2 0.0 0.7 LSM14B "bA11M20.3, C20orf40, FAM61B, FLJ25473, FT005, LSM13, RAP55B" ENSG00000149657 "LSM family member 14B" Q9BX40 20 62122461-62135374 "Predicted intracellular proteins" "Translation regulation" "Developmental protein, Ribonucleoprotein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 16 "Early spermatids: 215.2;Late spermatids: 560.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 2.2" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041274, HPA061189" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA041274: AB_2677388, HPA061189: AB_2684448" "unprognostic (2.24e-1)" "unprognostic (2.35e-1)" "unprognostic (2.89e-1)" "unprognostic (1.85e-2)" "unprognostic (1.20e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.61e-5)" "unprognostic (4.99e-2)" "unprognostic (2.28e-1)" "unprognostic (5.43e-2)" "unprognostic (4.93e-3)" "unprognostic (4.69e-2)" "unprognostic (3.34e-3)" "unprognostic (6.61e-2)" "unprognostic (2.00e-1)" "unprognostic (4.53e-3)" "unprognostic (1.98e-1)" 19.7 23.9 29.3 21.0 30.1 26.7 19.8 39.5 34.5 27.5 21.6 27.4 23.4 31.2 14.2 31.6 25.7 14.5 37.7 32.3 24.1 19.0 24.4 19.3 23.5 24.2 26.6 37.4 30.4 21.3 24.9 14.9 25.9 22.0 14.3 31.2 23.7 17.4 71.6 34.6 22.8 17.6 23.2 21.7 23.3 51.9 27.1 28.8 20.9 45.3 17.8 26.5 27.3 27.2 44.4 41.6 65.0 62.5 29.0 30.3 55.3 46.0 34.1 93.7 40.9 123.4 30.1 46.5 51.7 31.9 67.9 62.9 31.5 39.6 46.4 19.2 22.9 112.3 57.8 74.3 40.0 48.6 65.1 26.1 70.4 39.1 36.1 36.7 24.3 53.8 61.4 32.7 33.0 58.7 81.2 72.7 40.2 70.8 61.0 104.3 128.5 36.9 25.5 51.7 88.8 77.0 83.9 73.5 61.3 37.5 91.6 60.9 31.8 132.9 90.0 69.1 47.3 40.8 52.1 56.8 58.5 31.7 43.4 0.0 0.4 2.2 0.3 0.3 0.1 0.5 0.2 0.4 0.3 0.5 0.2 0.3 0.6 0.0 0.2 0.4 0.2 0.1 29.3 30.1 39.5 34.5 32.3 24.1 24.2 26.6 25.9 23.2 27.1 27.2 8.6 9.6 6.8 9.1 7.3 9.7 3.5 4.7 5.2 15.1 8.4 7.1 22.8 7.2 7.9 1.8 8.4 6.4 15.3 13.5 1.9 5.0 215.2 13.3 14.1 8.0 13.9 9.5 6.2 5.3 6.0 7.5 8.2 10.3 5.1 14.8 5.0 11.6 8.6 8.4 6.8 12.0 6.1 13.2 6.8 560.0 13.4 8.8 3.6 7.5 8.2 17.2 7.2 5.0 8.4 7.1 8.2 15.8 4.7 9.2 9.7 6.7 12.1 20.3 0.0 9.5 6.4 11.2 23.1 7.6 10.1 5.2 6.9 13.4 12.4 3.0 LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879835-56014169 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.8;lymphoid tissue: 85.4" "Cell type enhanced" "Detected in many" "B-cells: 237.5;Kupffer cells: 183.7;Macrophages: 226.0;monocytes: 182.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 64.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 198.4;HMC-1: 193.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 770000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" 17.2 7.3 3.9 79.2 4.0 73.8 9.2 7.4 8.7 11.0 7.8 14.2 36.3 6.2 4.8 8.6 10.0 23.5 5.4 4.4 5.5 5.9 14.9 28.2 49.2 9.4 7.2 3.6 9.5 6.3 4.8 23.5 8.3 5.6 13.3 8.9 17.0 9.7 1.6 3.7 31.6 14.2 7.2 85.4 13.3 3.1 9.0 10.4 10.6 4.4 53.1 29.7 5.7 11.2 47.2 24.6 6.9 0.7 0.5 0.0 43.6 34.6 54.7 21.0 15.7 18.0 15.5 41.2 15.0 12.1 15.3 19.3 22.2 23.8 14.6 70.0 19.8 198.4 6.9 5.5 4.0 20.6 193.4 0.8 7.8 0.6 13.6 13.1 27.2 0.0 98.3 90.2 3.0 3.3 0.1 21.5 38.6 72.9 2.1 3.3 9.6 5.0 9.8 24.9 4.5 74.8 17.3 0.1 7.5 44.9 3.4 41.4 33.1 0.0 10.0 0.1 15.0 26.4 13.2 102.4 1.5 38.8 1.7 4.5 12.2 22.7 1.6 28.3 1.3 15.9 0.3 0.6 10.3 16.1 0.2 0.7 64.4 4.3 49.1 16.2 0.0 5.0 3.9 4.0 7.4 8.7 4.4 5.5 9.4 7.2 8.3 7.2 9.0 11.2 21.0 35.3 37.5 27.7 237.5 5.4 23.8 32.4 4.6 6.3 10.3 7.0 2.2 18.6 44.5 9.2 2.1 2.9 130.0 14.5 0.0 21.8 0.9 14.6 26.2 28.1 6.0 40.4 1.1 53.0 65.2 13.6 18.8 15.9 72.8 0.5 22.9 13.2 126.6 0.0 2.5 14.1 14.2 183.7 96.1 2.4 3.4 226.0 5.4 92.8 182.6 54.3 94.7 13.0 1.7 40.7 13.3 1.2 58.9 62.9 26.0 2.1 40.9 2.6 19.7 3.7 6.4 1.2 2.1 4.9 5.8 38.7 25.0 62.5 17.1 82.4 MAN2B1 "LAMAN, MANB" ENSG00000104774 "Mannosidase alpha class 2B member 1" O00754 19 12646511-12666742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 32.8;Plasma cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 201.8;intermediate monocyte: 178.8;myeloid DC: 158.8;non-classical monocyte: 138.4;plasmacytoid DC: 187.5" "Group enriched" "Detected in all" 5 "dendritic cells: 187.5;monocytes: 201.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041530, HPA053404" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA041530: AB_10795639, HPA053404: " "unprognostic (6.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.20e-2)" "unprognostic (5.48e-2)" "unprognostic (3.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-2)" "unprognostic (9.55e-2)" "unprognostic (1.95e-1)" "unprognostic (2.79e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.94e-5)" "unprognostic (4.00e-1)" "unprognostic (4.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" 35.8 21.4 5.3 54.6 6.4 83.6 24.8 6.6 5.9 19.6 18.5 30.3 31.0 21.8 9.0 19.8 19.9 28.4 16.0 4.9 7.4 17.3 23.7 46.8 52.1 10.3 6.7 16.7 39.7 16.6 9.9 24.6 9.5 20.5 22.6 1.6 35.2 14.9 12.1 28.9 33.6 20.2 8.9 70.1 32.7 6.4 9.7 23.1 16.3 9.4 39.3 35.6 16.7 12.4 52.4 26.3 26.4 31.3 85.8 57.3 74.0 37.9 79.2 33.1 32.4 21.3 21.4 56.9 44.9 30.4 9.4 40.1 13.6 25.6 15.7 28.5 41.6 19.8 13.6 34.9 43.5 131.6 130.2 68.5 49.2 18.5 23.3 35.6 31.7 21.1 25.6 41.9 17.8 40.9 17.9 74.2 21.9 26.2 32.8 40.8 36.1 28.8 38.9 59.8 8.2 25.5 37.7 32.0 63.0 15.8 49.4 80.0 42.0 44.8 18.4 44.0 36.2 55.4 65.5 28.0 30.4 127.5 51.2 12.2 201.8 29.7 31.9 178.8 35.4 32.9 28.9 29.0 158.8 26.4 15.4 15.9 29.4 13.2 138.4 187.5 30.7 150.3 5.3 6.4 6.6 5.9 4.9 7.4 10.3 6.7 9.5 8.9 9.7 12.4 1.6 6.4 7.5 8.5 25.1 3.6 2.0 2.7 14.2 2.6 1.9 1.0 0.9 2.8 2.0 1.8 0.0 2.5 20.5 2.0 1.9 1.7 3.7 1.4 2.5 3.1 1.8 9.4 7.8 2.3 2.8 7.2 20.9 1.3 1.3 3.4 1.8 0.8 8.4 0.0 6.4 0.9 0.0 15.4 24.7 11.1 3.7 32.8 1.8 17.8 11.0 1.5 9.2 3.5 13.4 1.5 2.5 4.5 78.1 2.5 3.8 1.5 3.9 4.0 13.1 2.3 2.0 0.6 1.6 11.5 3.3 2.7 9.4 2.7 2.0 2.0 MANBA ENSG00000109323 "Mannosidase beta" O00462 4 102630770-102760994 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Macrophages: 74.0;Microglial cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.6" "Group enriched" "Detected in many" 5 "dendritic cells: 5.3;granulocytes: 16.6;monocytes: 9.1" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;hTCEpi: 13.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053478 Approved Supported Vesicles NA NA 15000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 57: B-cells - Immune response" Vesicles "HPA053478: AB_2682165" "unprognostic (2.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.80e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (4.11e-2)" "prognostic unfavorable (3.74e-6)" "unprognostic (1.32e-1)" "unprognostic (2.19e-1)" "unprognostic (4.87e-2)" "unprognostic (7.78e-2)" "unprognostic (1.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (7.12e-2)" "unprognostic (4.81e-2)" "unprognostic (2.13e-1)" 7.1 12.4 1.9 1.5 2.4 7.0 6.4 4.7 2.2 6.5 2.2 6.7 1.6 6.1 0.2 3.8 6.3 1.3 6.6 1.1 2.1 4.8 4.7 10.5 2.1 3.8 2.9 8.8 8.3 3.0 5.0 3.7 4.7 4.3 1.1 2.7 8.9 2.0 3.0 4.5 8.5 2.4 3.0 12.0 9.1 1.6 3.5 1.2 7.1 0.1 2.0 8.1 5.8 3.7 2.9 1.4 0.6 1.6 15.5 12.1 0.9 1.1 6.9 1.8 4.1 1.7 1.0 3.6 1.4 2.7 3.9 1.0 3.0 2.2 1.1 2.2 0.7 3.0 1.1 0.7 2.7 2.8 8.2 3.7 13.7 7.6 3.4 8.9 3.0 1.2 3.6 2.0 3.4 1.4 2.0 2.3 1.3 1.9 1.1 1.9 1.6 0.6 3.4 2.3 1.4 0.5 1.4 1.9 1.5 5.4 4.5 1.8 0.2 2.0 1.3 9.3 1.2 1.3 5.8 0.5 3.1 1.5 1.6 4.0 6.8 16.6 0.4 6.1 0.7 1.7 0.0 0.7 5.3 2.1 0.4 0.6 6.1 1.8 9.1 1.2 0.5 3.1 1.9 2.4 4.7 2.2 1.1 2.1 3.8 2.9 4.7 3.0 3.5 3.7 6.4 32.1 35.6 24.5 45.4 5.9 8.4 13.2 12.0 6.2 11.6 8.1 14.6 14.3 13.5 9.2 6.2 42.3 14.3 5.1 1.9 8.1 2.8 6.9 6.9 8.1 1.8 19.7 36.4 2.7 7.3 13.8 25.5 12.8 34.8 5.5 10.4 17.7 43.6 6.7 66.5 10.5 2.0 58.5 29.6 1.6 9.0 74.0 0.0 111.5 52.8 5.2 17.5 31.2 66.8 5.5 17.3 19.9 17.5 7.5 5.2 9.8 5.8 7.5 0.0 10.8 6.7 0.2 1.4 12.6 4.5 22.6 16.9 12.6 11.2 9.7 MARCHF1 "FLJ20668, MARCH-I, MARCH1, RNF171" ENSG00000145416 "Membrane associated ring-CH-type finger 1" Q8TCQ1 4 163524298-164384050 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 31.6;retina: 27.5" "Group enriched" "Detected in some" 4 "B-cells: 21.4;Hofbauer cells: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 94 "classical monocyte: 41.8;eosinophil: 25.5;intermediate monocyte: 41.0;memory B-cell: 42.3;myeloid DC: 44.2;naive B-cell: 35.8;non-classical monocyte: 45.4;plasmacytoid DC: 16.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 7.1;U-266/70: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014600, HPA048024" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Vesicles "Endoplasmic reticulum, Golgi apparatus" "HPA014600: AB_1853573, HPA048024: " "unprognostic (7.29e-2)" "unprognostic (5.82e-2)" "unprognostic (1.48e-1)" "unprognostic (9.09e-2)" "unprognostic (8.25e-2)" "unprognostic (2.98e-2)" "unprognostic (4.79e-3)" "unprognostic (9.00e-2)" "unprognostic (3.00e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-1)" "unprognostic (2.20e-1)" "unprognostic (1.24e-1)" "unprognostic (7.00e-2)" "unprognostic (2.48e-2)" "unprognostic (2.70e-1)" "unprognostic (2.91e-2)" 6.4 3.5 7.8 21.5 8.1 3.9 2.7 3.6 7.7 3.1 1.8 3.5 3.9 2.5 0.7 3.0 2.8 5.3 1.7 6.6 10.1 1.8 4.1 8.0 31.6 8.0 8.2 2.7 2.8 0.8 2.5 9.9 6.9 2.3 4.5 27.5 3.2 1.2 1.0 4.5 7.0 6.2 7.0 25.8 3.9 1.7 12.1 5.6 2.1 1.0 25.5 7.7 2.9 14.4 0.6 0.5 2.1 1.2 0.0 0.0 1.3 0.9 0.0 0.0 0.0 1.2 2.4 7.1 2.5 0.0 0.2 1.0 0.0 0.0 0.0 0.8 0.7 5.0 3.0 0.5 0.0 3.1 1.6 0.0 0.0 0.0 0.1 2.8 0.0 1.3 1.9 3.6 2.4 0.7 1.8 1.9 2.6 0.2 0.9 2.0 0.3 0.5 0.1 1.1 1.0 0.9 0.6 1.0 0.4 1.4 2.9 0.5 2.3 0.8 1.4 0.5 1.7 7.0 2.5 1.9 0.9 1.5 1.1 0.0 41.8 25.5 0.1 41.0 0.0 42.3 0.1 0.0 44.2 35.8 0.0 0.0 0.3 0.3 45.4 16.5 0.0 18.4 7.8 8.1 3.6 7.7 6.6 10.1 8.0 8.2 6.9 7.0 12.1 14.4 0.1 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 46.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 MARCHF3 "MARCH-III, MARCH3, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030558 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 43.8;Syncytiotrophoblasts: 98.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.5;naive B-cell: 12.1" "Lineage enriched" "Detected in many" 4 "B-cells: 12.1" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 40.4;HUVEC TERT2: 27.4;TIME: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043406 Uncertain Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA043406: AB_10793947" "unprognostic (5.96e-3)" "unprognostic (1.46e-2)" "unprognostic (1.91e-2)" "unprognostic (4.21e-2)" "unprognostic (9.00e-3)" "unprognostic (1.17e-2)" "unprognostic (7.75e-3)" "unprognostic (9.41e-2)" "unprognostic (8.93e-2)" "unprognostic (2.05e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (5.60e-6)" "unprognostic (7.74e-2)" "unprognostic (7.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.64e-1)" 5.6 2.8 6.1 2.9 5.6 3.7 2.6 5.3 4.1 0.9 1.9 5.3 0.9 1.4 0.0 1.4 1.5 5.2 7.8 3.9 5.7 0.8 0.7 2.4 2.5 11.5 7.1 1.1 2.4 0.3 2.4 1.7 7.9 0.6 5.6 7.4 4.6 0.2 6.5 5.8 2.4 2.9 8.3 1.6 2.4 5.6 7.8 1.3 1.4 3.3 2.1 7.6 0.7 8.5 0.4 1.8 3.9 2.1 3.4 3.2 1.2 14.2 5.9 11.1 16.3 1.9 0.8 3.8 1.3 1.9 2.4 1.1 4.9 2.5 15.3 0.8 4.7 12.2 3.2 1.9 5.6 5.0 3.0 2.4 0.7 40.4 4.8 2.6 27.4 0.6 5.1 0.7 9.3 1.3 0.5 2.3 3.3 3.0 4.6 1.5 15.5 1.2 0.9 2.0 1.3 0.9 3.3 0.5 1.6 1.9 2.9 5.0 33.5 2.2 1.8 12.6 1.6 1.9 2.3 2.3 8.3 3.8 2.0 0.0 0.2 2.8 0.5 0.4 0.1 10.5 0.6 0.3 0.1 12.1 2.3 0.5 0.8 2.3 0.3 0.7 2.9 0.8 6.1 5.6 5.3 4.1 3.9 5.7 11.5 7.1 7.9 8.3 7.8 8.5 3.8 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 43.8 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.2 5.8 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 98.6 0.6 0.0 0.0 0.0 MARF1 "KIAA0430, LKAP, LMKB, PPP1R34" ENSG00000166783 "Meiosis regulator and mRNA stability factor 1" Q9Y4F3 16 15594387-15643154 "Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 28.7;Breast glandular cells: 26.3;Endometrial stromal cells: 27.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017992 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus, Vesicles" "HPA017992: AB_1852921" "unprognostic (2.33e-1)" "unprognostic (6.44e-3)" "unprognostic (8.84e-2)" "unprognostic (3.78e-2)" "unprognostic (1.28e-1)" "unprognostic (6.13e-3)" "unprognostic (2.35e-1)" "unprognostic (2.10e-2)" "unprognostic (2.47e-2)" "unprognostic (6.93e-2)" "unprognostic (8.44e-3)" "unprognostic (1.35e-1)" "unprognostic (6.94e-3)" "unprognostic (3.08e-2)" "unprognostic (1.24e-1)" "unprognostic (8.74e-2)" "unprognostic (7.94e-2)" 10.5 7.1 2.1 10.8 5.2 9.7 9.4 1.5 6.6 10.0 3.7 16.0 10.4 12.8 1.0 12.3 13.7 12.5 9.2 4.5 3.4 13.5 8.3 9.3 14.6 3.6 4.5 18.2 12.9 12.3 5.9 9.4 2.6 10.4 12.1 8.4 14.4 13.7 18.3 10.5 11.2 12.0 0.0 12.1 10.1 4.9 4.4 12.7 14.8 15.2 22.0 12.1 8.8 4.5 8.3 9.4 15.0 8.2 12.1 22.4 7.2 9.6 12.4 8.2 13.5 2.7 6.2 29.8 17.0 12.3 6.7 5.6 7.7 12.4 13.6 11.6 5.0 13.1 12.3 10.4 13.4 15.7 10.5 13.4 13.4 15.3 15.5 16.9 19.5 12.8 12.6 13.3 15.6 7.7 13.9 2.6 5.6 7.1 7.2 19.5 22.0 5.9 7.1 6.4 9.1 10.8 7.7 8.9 14.3 6.7 9.2 13.2 19.7 11.2 5.5 11.6 6.3 12.3 12.9 15.9 12.4 9.6 16.4 2.5 0.7 4.6 1.1 1.2 0.7 4.1 1.7 1.3 0.8 5.2 1.9 1.4 7.1 0.9 1.8 0.3 1.7 0.9 2.1 5.2 1.5 6.6 4.5 3.4 3.6 4.5 2.6 0.0 4.4 4.5 21.4 22.4 28.7 0.0 10.7 0.0 0.0 0.0 0.0 0.0 26.3 19.8 0.0 0.0 18.6 23.9 0.0 5.7 14.7 0.0 15.6 10.4 0.0 17.8 27.5 8.4 0.0 0.0 0.0 14.2 5.9 7.7 0.0 20.0 11.4 23.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 7.2 0.0 0.0 0.0 0.0 13.7 0.0 0.0 6.8 0.0 0.0 19.0 17.5 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 7.7 7.8 17.9 0.0 0.0 MAST1 "KIAA0973, SAST" ENSG00000105613 "Microtubule associated serine/threonine kinase 1" Q9Y2H9 19 12833951-12874952 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 37.7;pituitary gland: 23.3;retina: 15.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.7;Cone photoreceptor cells: 43.8;Excitatory neurons: 64.7;Inhibitory neurons: 70.3;Oligodendrocyte precursor cells: 22.1;Rod photoreceptor cells: 20.4" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Region enhanced" "Detected in many" "cerebral cortex: 37.7" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "AN3-CA: 23.3;SCLC-21H: 40.5;SH-SY5Y: 20.2;U-266/70: 16.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028181, HPA073106" Enhanced Supported Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Cytosol "HPA028181: AB_10603872, HPA073106: AB_2732218" "unprognostic (6.32e-2)" "unprognostic (3.66e-2)" "unprognostic (3.93e-2)" "unprognostic (2.83e-5)" "unprognostic (1.72e-1)" "unprognostic (4.19e-2)" "unprognostic (2.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "unprognostic (8.89e-3)" "unprognostic (3.43e-2)" "unprognostic (3.84e-3)" "unprognostic (1.19e-1)" "unprognostic (7.04e-2)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" 0.0 2.2 6.5 0.3 12.1 0.3 0.1 7.3 37.7 0.2 0.0 1.2 0.3 0.0 0.0 0.2 0.1 0.2 0.2 8.3 2.4 0.1 0.6 0.1 0.1 11.2 1.1 0.3 0.6 0.5 23.3 0.0 9.5 0.2 0.1 15.4 0.2 0.0 0.0 3.7 0.4 0.0 0.0 0.1 0.6 5.0 1.2 0.8 0.1 0.0 0.0 0.2 0.3 3.0 3.6 1.6 1.5 23.3 0.0 0.0 1.9 0.2 0.1 0.3 0.9 0.8 1.5 5.8 2.6 0.0 3.9 0.1 6.8 0.1 0.1 4.1 4.5 0.5 5.8 2.6 0.0 1.3 1.2 0.5 0.1 0.8 0.7 1.3 0.0 15.2 5.2 3.0 0.0 0.8 2.4 0.6 6.9 0.6 7.2 15.9 4.6 8.3 0.3 0.2 40.5 20.2 0.8 1.4 4.3 1.2 3.8 2.1 0.0 2.8 4.2 3.1 0.8 16.7 14.5 3.7 5.1 3.1 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 6.5 12.1 7.3 37.7 8.3 2.4 11.2 1.1 9.5 0.0 1.2 3.0 0.5 0.0 2.4 7.8 0.2 0.9 1.6 0.6 0.6 24.7 0.8 2.5 1.0 0.0 0.3 0.0 43.8 0.6 0.4 0.6 0.0 0.4 14.0 0.2 0.2 1.3 0.0 0.0 64.7 0.5 0.6 1.3 0.0 0.3 1.3 0.5 1.1 0.5 0.2 15.2 70.3 0.1 0.0 1.0 1.2 8.2 0.6 0.7 5.4 6.5 0.1 3.7 0.0 22.1 3.0 0.3 2.5 1.2 0.0 1.0 0.9 0.2 1.0 20.4 0.0 2.0 0.5 8.0 5.2 0.7 1.4 0.3 1.0 0.4 0.7 1.2 MCOLN1 "ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1" ENSG00000090674 "Mucolipin 1" Q9GZU1 19 7522624-7534009 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Ion channel" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 109.4;Kupffer cells: 117.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 117.5;classical monocyte: 45.2;eosinophil: 105.7;intermediate monocyte: 95.5;neutrophil: 41.1;non-classical monocyte: 105.1" "Group enriched" "Detected in all" 5 "granulocytes: 117.5;monocytes: 105.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031763, CAB032637, HPA069495" Uncertain Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" Nucleoplasm "CAB032637: AB_2142964, HPA031763: AB_10600822, HPA069495: " "unprognostic (5.51e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-2)" "unprognostic (3.30e-2)" "unprognostic (2.66e-1)" "unprognostic (4.07e-2)" "unprognostic (8.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.79e-2)" "unprognostic (1.47e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.36e-1)" "prognostic favorable (5.67e-4)" "unprognostic (2.58e-1)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" 21.2 37.4 6.4 9.2 6.5 10.4 15.3 7.0 8.4 11.7 8.3 13.6 8.3 11.6 2.7 11.0 12.2 10.1 15.7 7.0 7.4 11.7 14.7 20.3 13.2 8.2 7.4 10.0 9.9 10.2 21.7 15.9 9.0 8.7 5.6 5.0 12.3 6.1 22.2 20.8 12.1 8.1 7.1 48.2 12.8 5.6 8.2 6.2 8.5 11.7 4.1 15.8 10.9 9.9 11.6 11.7 5.6 19.1 32.0 10.3 16.1 21.2 16.9 25.2 21.6 9.0 10.0 6.5 25.5 14.5 22.2 5.3 9.5 7.3 7.4 12.7 21.1 5.8 11.0 7.3 28.0 6.6 24.5 14.5 16.8 24.1 4.2 7.9 10.7 14.2 10.9 27.9 14.7 3.9 9.1 6.6 12.6 6.1 24.8 12.6 9.4 13.8 9.6 9.9 14.4 17.8 9.1 15.8 26.8 6.1 9.6 11.4 13.5 12.0 6.9 48.8 16.0 21.5 35.5 4.7 19.2 9.2 18.4 117.5 45.2 105.7 7.7 95.5 6.3 4.2 6.5 6.3 19.2 4.1 6.0 6.5 41.1 10.3 105.1 21.1 10.0 17.1 6.4 6.5 7.0 8.4 7.0 7.4 8.2 7.4 9.0 7.1 8.2 9.9 15.1 3.2 2.6 5.9 8.0 13.4 6.5 16.9 10.2 27.3 15.9 15.0 2.3 15.7 8.1 31.3 22.9 11.6 12.1 32.0 1.9 23.7 4.8 5.0 19.8 14.1 16.8 21.7 10.6 23.1 20.0 16.0 9.7 6.5 1.3 22.2 13.6 13.6 109.4 58.9 8.0 10.0 22.4 117.1 32.2 17.0 16.4 70.6 21.4 7.5 18.0 23.0 16.5 7.5 11.4 23.4 19.3 15.8 8.0 5.6 21.8 12.3 6.5 44.1 6.6 11.2 14.8 10.3 14.7 8.9 17.3 29.6 8.7 17.3 9.4 4.8 MEF2C ENSG00000081189 "Myocyte enhancer factor 2C" Q06413 5 88717117-88904257 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 555.4;tongue: 246.8" "Cell type enhanced" "Detected in many" "B-cells: 471.5;Excitatory neurons: 735.7;Inhibitory neurons: 759.5;Microglial cells: 730.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 29.7;basal ganglia: 58.6;cerebral cortex: 75.3;hippocampal formation: 55.7" "Group enriched" "Detected in many" 4 "classical monocyte: 72.0;intermediate monocyte: 82.6;memory B-cell: 141.6;myeloid DC: 95.2;naive B-cell: 187.9;non-classical monocyte: 71.5;plasmacytoid DC: 100.3" "Group enriched" "Detected in many" 5 "B-cells: 187.9;dendritic cells: 100.3;monocytes: 82.6" "Cell line enhanced" "Detected in many" "Daudi: 103.6;HEL: 229.3;Karpas-707: 121.6;REH: 261.8;WM-115: 145.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 70.0;cerebral cortex: 253.1;hippocampal formation: 220.0;olfactory bulb: 66.8" "HPA005533, CAB068196, CAB068197" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "CAB068196: AB_2665646, CAB068197: AB_2665645, HPA005533: AB_1079352" "unprognostic (2.74e-1)" "unprognostic (1.64e-2)" "unprognostic (2.37e-2)" "unprognostic (8.78e-2)" "unprognostic (9.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.06e-1)" "unprognostic (3.19e-2)" "unprognostic (3.52e-2)" "unprognostic (8.73e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (7.18e-3)" "unprognostic (1.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.42e-2)" 28.9 26.8 29.7 39.2 58.6 11.1 17.5 0.0 75.3 18.8 0.0 15.9 6.9 25.9 7.3 13.6 17.3 28.5 35.2 55.7 0.0 10.4 10.5 21.3 62.9 0.0 0.0 34.9 5.6 9.3 6.3 45.5 0.0 20.0 15.4 34.2 9.0 17.7 555.4 4.9 11.2 31.5 0.0 43.8 12.7 9.4 0.0 12.8 21.7 246.8 77.7 21.3 7.6 11.0 1.6 0.0 7.1 0.0 7.7 4.6 0.2 2.2 4.5 0.3 1.0 0.2 1.0 103.6 0.6 12.0 2.5 3.1 9.6 9.1 0.2 31.7 12.5 229.3 12.3 0.0 2.8 10.4 0.6 21.6 0.0 0.3 0.0 1.4 35.1 0.0 12.3 121.6 9.0 0.0 0.3 0.1 2.2 0.1 8.4 261.8 63.1 50.5 0.0 1.2 0.0 8.3 0.0 0.7 29.5 3.9 0.3 58.0 40.4 5.6 1.0 0.6 5.4 92.0 11.5 62.0 1.5 70.1 145.2 0.6 72.0 0.2 0.2 82.6 0.1 141.6 0.2 0.1 95.2 187.9 0.2 0.2 24.3 16.7 71.5 100.3 0.5 34.4 29.7 58.6 0.0 75.3 55.7 0.0 0.0 0.0 0.0 0.0 0.0 11.0 367.4 32.1 52.0 117.5 471.5 10.7 4.2 0.0 7.4 22.6 5.2 26.5 86.4 10.0 21.7 1.8 214.8 0.8 138.6 9.2 27.4 0.8 11.0 0.8 13.4 197.5 1.2 59.1 735.7 12.7 1.2 26.8 2.0 1.0 5.1 107.5 283.4 3.4 171.1 5.0 759.5 1.5 0.0 205.8 127.5 8.6 29.8 205.1 67.6 730.7 202.7 61.8 8.2 119.6 18.7 0.4 3.0 71.8 314.7 2.1 0.2 0.8 3.7 202.9 335.2 72.7 257.6 4.0 29.5 2.5 8.4 1.6 12.2 58.6 6.3 2.3 MFSD8 "CLN7, MGC33302" ENSG00000164073 "Major facilitator superfamily domain containing 8" Q8NHS3 4 127917799-127966034 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044802 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" Vesicles Nucleoplasm "HPA044802: AB_10963221" "unprognostic (1.67e-1)" "unprognostic (1.95e-1)" "unprognostic (4.47e-2)" "unprognostic (8.10e-2)" "unprognostic (1.57e-1)" "unprognostic (4.12e-2)" "unprognostic (1.18e-1)" "unprognostic (8.99e-2)" "unprognostic (2.19e-2)" "unprognostic (8.69e-2)" "unprognostic (4.51e-2)" "unprognostic (3.44e-2)" "unprognostic (3.93e-3)" "unprognostic (1.70e-1)" "unprognostic (5.61e-3)" "unprognostic (3.14e-1)" "prognostic favorable (2.21e-4)" 4.6 5.7 1.3 6.8 1.3 2.6 6.9 1.9 1.6 6.2 1.1 6.8 10.0 5.6 3.9 5.4 5.5 4.8 3.8 1.1 1.7 6.4 10.0 4.8 5.4 1.4 1.3 6.8 8.1 9.1 7.1 5.9 1.5 5.5 8.2 4.6 5.8 4.4 3.7 5.9 7.6 5.8 1.1 7.3 6.4 3.9 0.8 5.2 7.0 4.4 7.9 5.3 5.9 2.2 10.9 7.3 9.5 4.6 7.2 6.9 7.0 8.3 10.3 10.2 10.5 5.2 14.3 5.2 14.5 14.3 14.8 7.8 10.2 7.4 14.4 10.8 7.9 5.7 9.1 8.0 9.4 6.0 6.6 8.3 2.7 8.6 7.7 5.0 10.6 6.6 9.5 5.9 14.6 8.9 5.0 1.9 1.7 11.8 5.2 5.3 0.6 4.7 7.5 13.9 8.5 2.9 9.0 12.0 3.5 6.4 5.6 5.1 6.7 2.9 3.1 10.7 7.8 12.5 22.1 9.6 10.3 5.3 8.8 1.9 1.6 2.8 2.5 2.4 2.4 2.5 2.7 2.2 1.6 1.1 2.4 2.6 2.5 2.4 3.7 2.2 3.4 1.2 1.3 1.3 1.9 1.6 1.1 1.7 1.4 1.3 1.5 1.1 0.8 2.2 9.5 12.8 14.1 17.0 18.8 3.2 4.9 8.5 10.2 17.2 8.1 5.3 3.0 5.7 14.0 16.5 20.9 12.5 17.9 7.2 1.9 8.5 10.4 7.7 7.2 7.2 4.2 3.8 32.1 7.0 7.3 8.6 11.7 8.2 12.7 18.4 8.9 10.1 7.6 11.8 34.9 6.8 10.2 8.5 3.3 14.7 9.3 6.5 3.6 27.2 10.5 8.6 20.6 20.6 24.6 7.8 9.5 9.4 19.9 5.4 11.1 6.3 12.1 24.9 6.6 5.8 6.6 12.6 8.4 8.9 5.7 22.0 13.7 11.4 7.3 4.8 MGRN1 "KIAA0544, RNF156" ENSG00000102858 "Mahogunin ring finger 1" O60291 16 4616493-4690974 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 16.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007653, HPA008033" Approved Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "Endoplasmic reticulum" "HPA007653: AB_1846304, HPA008033: " "unprognostic (2.27e-1)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "unprognostic (1.97e-2)" "unprognostic (4.24e-1)" "unprognostic (1.26e-2)" "unprognostic (9.96e-2)" "unprognostic (1.70e-1)" "unprognostic (4.03e-2)" "unprognostic (9.47e-2)" "unprognostic (6.41e-2)" "unprognostic (2.32e-1)" "unprognostic (9.06e-2)" "unprognostic (1.79e-1)" "unprognostic (5.04e-2)" 23.3 34.3 18.6 25.0 20.6 32.6 22.8 11.9 25.4 28.3 4.9 30.6 28.9 36.9 6.8 20.4 32.1 19.7 26.9 26.4 11.4 24.0 53.5 30.3 18.1 14.1 10.4 30.5 34.6 18.5 33.2 18.5 8.8 30.1 10.9 9.0 25.6 20.5 52.1 23.0 29.9 17.5 8.1 37.7 35.3 18.0 12.0 11.7 28.8 16.7 10.9 28.2 20.6 24.3 13.6 63.9 32.4 33.2 19.0 18.4 44.0 28.7 20.0 23.6 20.0 42.5 31.4 40.0 36.2 35.0 17.6 21.4 26.0 23.6 7.0 56.0 28.8 22.0 45.2 59.6 34.7 32.1 52.3 34.2 15.0 33.0 14.1 17.0 23.0 26.0 32.7 28.6 16.4 59.7 33.3 42.9 48.0 19.2 27.4 60.7 17.0 54.3 20.8 39.3 51.8 42.8 47.6 50.6 28.2 14.8 30.7 31.4 40.8 43.7 24.1 124.3 25.0 44.6 37.8 27.2 18.6 31.8 32.0 5.4 3.5 3.8 2.5 3.9 2.3 1.3 1.4 2.3 2.4 1.5 3.2 1.9 16.2 1.4 2.6 4.1 1.7 3.7 18.6 20.6 11.9 25.4 26.4 11.4 14.1 10.4 8.8 8.1 12.0 24.3 14.7 25.6 34.0 24.2 22.2 9.2 29.5 10.0 6.2 27.3 15.8 11.0 11.4 22.8 9.6 18.4 43.8 23.5 28.2 27.7 5.9 18.6 16.2 20.1 24.2 16.9 37.0 13.7 26.6 22.7 17.7 19.0 44.9 24.5 14.0 30.4 15.0 34.8 30.4 25.2 25.0 23.5 4.1 30.1 21.4 27.2 26.8 27.0 21.4 8.4 36.5 20.8 23.7 18.6 29.8 32.0 15.8 24.8 29.0 23.7 31.7 13.9 11.1 35.2 0.0 20.4 17.6 9.3 12.5 11.9 16.3 34.2 24.0 29.8 23.1 27.8 MINDY4 "C7orf67, FAM188B, FLJ22374" ENSG00000106125 "MINDY lysine 48 deubiquitinase 4" Q4G0A6 7 30771417-30892387 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Collecting duct cells: 12.9;Endometrial ciliated cells: 36.7;Endometrial stromal cells: 8.9;Respiratory ciliated cells: 18.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019475, HPA030129, HPA030130" Approved Supported Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" "Vesicles, Cytosol" "HPA019475: AB_1848806, HPA030129: AB_10599621, HPA030130: AB_10601565" "unprognostic (2.96e-1)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (4.07e-1)" "unprognostic (6.01e-3)" "unprognostic (3.81e-2)" "unprognostic (5.25e-3)" "unprognostic (1.97e-1)" "unprognostic (5.59e-3)" "unprognostic (2.96e-2)" "unprognostic (1.92e-1)" "unprognostic (9.55e-2)" "unprognostic (1.12e-2)" "unprognostic (1.05e-1)" "unprognostic (2.18e-1)" 6.7 3.7 2.1 1.2 3.5 2.4 4.4 0.4 4.2 5.7 10.6 4.6 1.3 5.4 8.4 2.9 11.5 5.6 4.7 1.9 1.8 4.9 2.1 9.5 1.2 2.8 4.5 8.9 3.4 4.8 5.6 3.3 2.2 5.9 2.1 2.1 3.1 8.1 2.3 3.2 2.2 5.9 1.8 1.2 3.2 9.0 2.4 1.2 6.7 3.5 0.9 4.3 3.7 2.5 2.4 6.0 3.1 9.5 2.7 10.3 4.5 3.5 6.0 2.6 2.2 0.0 4.4 0.0 3.9 2.3 3.6 2.6 2.1 2.0 2.5 0.0 3.5 1.9 3.2 0.0 3.3 2.7 1.3 5.3 3.1 7.7 1.5 0.2 3.8 1.7 19.2 1.1 2.2 0.0 1.5 0.8 8.9 8.5 1.4 0.4 0.0 0.6 7.1 1.2 5.7 7.7 2.3 12.5 1.3 3.5 6.4 2.0 2.3 0.1 1.4 2.7 1.5 2.5 3.5 0.0 4.9 0.1 11.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.1 3.5 0.4 4.2 1.9 1.8 2.8 4.5 2.2 1.8 2.4 2.5 5.2 9.6 3.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.1 2.4 0.0 0.0 1.8 12.9 0.0 2.3 0.5 0.0 3.9 2.8 0.0 36.7 8.9 2.3 0.0 0.0 0.0 1.3 4.1 2.7 0.0 3.9 2.5 4.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 2.4 18.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.5 0.2 4.1 0.0 0.0 MMP3 "STMY, STMY1" ENSG00000149968 "Matrix metallopeptidase 3" P08254 11 102835801-102843609 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 90.7;salivary gland: 286.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 20.4;Basal respiratory cells: 25.8;Early spermatids: 24.2;Extravillous trophoblasts: 13.4;Fibroblasts: 17.9;Prostatic glandular cells: 11.9;Smooth muscle cells: 10.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 59.9" "Region enriched" "Detected in some" 4 "thalamus: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "BJ: 1545.7;BJ hTERT+: 4229.3;fHDF/TERT166: 1846.6" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 3.2" HPA007875 Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA 2540000 460000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA007875: AB_1079396" "unprognostic (2.27e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.63e-3)" "unprognostic (5.11e-3)" "unprognostic (3.78e-1)" "unprognostic (5.11e-2)" "unprognostic (5.26e-6)" "unprognostic (3.46e-2)" "unprognostic (7.14e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (3.26e-2)" "unprognostic (1.22e-15)" "unprognostic (3.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (2.34e-1)" 90.7 0.1 0.3 20.1 0.4 0.0 36.6 0.2 1.6 0.3 0.1 6.1 2.4 38.1 0.2 0.8 0.2 1.9 0.2 0.4 1.6 0.4 1.6 0.3 0.0 0.4 0.4 0.1 0.3 0.1 0.9 0.4 0.3 2.2 2.3 0.0 286.1 2.2 39.6 63.7 4.5 1.6 0.3 0.0 10.5 0.1 7.3 0.1 2.6 0.4 1.3 13.9 0.5 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1545.7 4229.3 27.0 8.7 0.1 0.2 0.0 0.0 1846.6 96.9 0.0 0.1 0.1 45.1 0.0 0.0 0.0 0.0 1.0 0.7 0.0 0.0 4.6 0.2 122.0 5.3 0.0 0.0 0.0 0.2 0.3 4.7 0.0 0.0 0.0 0.2 0.4 0.9 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.3 0.0 0.0 0.9 0.0 0.3 0.0 140.5 13.1 1.6 0.5 0.0 0.0 0.2 56.8 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 1.6 0.4 1.6 0.4 0.4 0.3 0.3 7.3 0.3 0.0 3.2 0.0 0.0 0.0 8.4 20.4 25.8 0.0 0.0 0.1 0.1 0.3 4.3 7.6 0.0 0.0 0.1 0.0 0.0 0.0 0.8 24.2 0.0 0.3 0.5 0.0 0.0 0.2 1.4 13.4 17.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.1 0.0 2.2 1.2 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.5 4.0 0.0 0.0 11.9 1.0 0.9 0.1 0.0 0.0 1.8 10.2 0.0 1.8 0.0 3.4 0.3 0.6 0.0 0.8 7.4 MPO ENSG00000005381 Myeloperoxidase P05164 17 58269855-58280935 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "bone marrow: 4023.1" "Cell type enriched" "Detected in some" 30 "Erythroid cells: 87.4" "Cancer enhanced" "Detected in single" "stomach cancer: 1.1" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 6.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 94 "HL-60: 3517.4;NB-4: 4589.9" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000059, HPA021147, HPA061464" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" No NA 576000000 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles Nucleoplasm "CAB000059: AB_2335676, HPA021147: AB_1854083, HPA061464: AB_2684531" "unprognostic (1.91e-1)" "unprognostic (9.08e-2)" "unprognostic (4.62e-2)" "unprognostic (2.90e-2)" "unprognostic (2.13e-3)" "unprognostic (2.78e-1)" "unprognostic (3.23e-1)" "unprognostic (2.91e-1)" "unprognostic (2.56e-1)" "unprognostic (1.68e-1)" "unprognostic (6.92e-2)" "unprognostic (8.34e-3)" "unprognostic (4.91e-2)" "unprognostic (3.07e-3)" "unprognostic (2.83e-1)" "unprognostic (1.14e-2)" "unprognostic (8.05e-2)" 0.5 0.4 0.8 0.6 0.6 4023.1 0.3 0.6 1.1 0.0 0.3 0.2 0.0 0.2 1.1 0.1 0.1 0.3 1.1 0.8 0.7 0.2 1.8 8.4 1.7 0.9 1.0 0.1 0.1 0.0 1.5 1.4 0.9 0.2 0.2 0.4 66.3 0.1 1.1 4.3 0.2 0.3 0.8 21.7 0.1 0.4 0.8 10.9 0.3 0.3 0.2 0.5 0.1 0.7 0.4 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 3517.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4589.9 0.0 0.0 0.0 5.3 3.2 0.6 0.0 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.1 0.0 4.0 0.0 0.0 6.2 0.0 0.0 3.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.4 0.0 0.6 0.0 0.1 7.5 0.8 0.6 0.6 1.1 0.8 0.7 0.9 1.0 0.9 0.8 0.8 0.7 0.0 0.0 0.5 0.7 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.9 0.0 0.5 0.1 0.0 0.1 0.0 87.4 0.3 0.2 0.9 0.7 0.0 0.0 0.0 0.0 0.7 0.3 0.9 0.0 0.2 0.0 0.0 1.2 0.0 1.3 0.0 2.9 0.0 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.1 0.3 0.1 0.0 0.1 0.6 0.0 0.0 0.0 MPV17L "FLJ39599, MLPH1, MLPH2, MPV17L1" ENSG00000156968 "MPV17 mitochondrial inner membrane protein like" Q2QL34 16 15395754-15413271 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 14.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 29.5;SK-BR-3: 8.2" "Low region specificity" "Detected in all" HPA041180 Approved Supported Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA041180: AB_10794266" "unprognostic (9.65e-2)" "unprognostic (8.74e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-3)" "unprognostic (6.68e-2)" "unprognostic (2.84e-1)" "unprognostic (2.73e-1)" "unprognostic (4.38e-3)" "unprognostic (8.41e-2)" "unprognostic (8.99e-3)" "unprognostic (8.70e-2)" "unprognostic (6.36e-3)" "prognostic favorable (1.48e-11)" "unprognostic (2.84e-1)" "unprognostic (7.60e-2)" "unprognostic (6.61e-3)" "unprognostic (3.87e-2)" 1.8 2.5 1.2 1.8 0.1 4.4 6.4 1.9 2.2 2.8 0.0 2.3 3.4 2.0 0.3 1.0 1.8 2.4 1.6 0.1 0.0 3.3 9.1 0.9 2.3 0.1 0.0 2.1 14.1 2.4 3.2 0.6 0.3 2.0 1.0 4.4 7.1 1.8 8.0 4.5 2.3 0.8 0.0 1.8 1.8 1.0 0.5 0.2 2.2 2.4 0.6 1.9 1.3 0.4 1.0 1.9 0.8 0.8 0.2 0.1 1.2 0.5 0.0 0.0 0.0 1.9 3.4 1.5 1.3 0.6 0.5 1.5 3.0 0.0 0.0 1.2 0.8 5.9 4.6 3.9 0.3 3.6 29.5 0.3 0.4 0.1 0.2 0.5 0.0 1.6 2.3 3.3 0.1 1.9 1.4 2.3 1.7 0.3 0.1 2.0 0.6 1.6 0.5 0.8 4.8 1.6 2.7 8.2 0.2 0.9 1.8 2.6 2.6 1.3 0.8 1.1 1.1 1.4 0.6 1.7 0.7 1.7 0.5 1.7 1.2 0.2 0.8 0.9 0.6 0.8 0.5 0.8 0.4 1.2 0.4 0.8 1.8 1.1 0.4 0.7 0.4 0.6 1.2 0.1 1.9 2.2 0.1 0.0 0.1 0.0 0.3 0.0 0.5 0.4 2.5 6.4 8.8 3.9 2.0 7.9 14.4 8.2 0.0 12.8 11.4 6.0 6.0 14.3 13.1 0.0 10.4 0.5 4.1 2.7 15.6 7.5 4.6 5.4 9.2 6.6 1.2 2.1 5.6 12.9 0.5 8.1 2.0 10.7 6.3 7.6 4.2 29.1 1.0 8.4 5.9 8.7 2.0 13.6 20.6 0.8 7.2 6.0 21.4 2.8 0.7 6.2 0.0 7.5 3.2 5.9 15.3 14.3 1.4 9.6 9.3 19.9 21.0 16.6 0.0 23.5 6.7 9.0 2.0 0.6 11.5 0.5 9.9 4.4 12.1 10.1 MSLN "CAK1, MPF" ENSG00000102854 Mesothelin Q13421 16 760734-768865 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 93.4;fallopian tube: 278.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 189.1;Alveolar cells type 2: 85.6;Club cells: 121.9;Glandular and luminal cells: 57.1;Paneth cells: 214.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 343.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 5.9" "Group enriched" "Detected in many" 39 "dendritic cells: 5.9;monocytes: 1.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 513.4;EFO-21: 77.4;HeLa: 173.4;hTCEpi: 111.5;OE19: 96.4" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 9 "spinal cord: 1.7" "CAB002216, HPA017172" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 17000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "CAB002216: AB_563874, HPA017172: AB_1853819" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (2.06e-2)" "unprognostic (1.33e-1)" "unprognostic (3.43e-2)" "unprognostic (3.95e-2)" "unprognostic (2.46e-1)" "unprognostic (9.47e-2)" "unprognostic (8.57e-2)" "unprognostic (4.69e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (2.63e-1)" "prognostic favorable (5.91e-4)" "unprognostic (2.00e-2)" "unprognostic (1.60e-1)" "unprognostic (2.14e-2)" "unprognostic (3.35e-2)" 93.4 0.2 0.7 1.1 1.0 3.2 0.5 0.6 1.5 15.9 0.3 8.9 7.1 6.2 24.1 7.1 278.2 16.4 8.4 0.7 0.8 6.5 0.2 71.8 0.2 1.9 1.2 3.7 0.9 0.1 0.7 2.7 1.3 3.8 4.0 0.7 39.3 9.9 0.0 1.4 2.9 3.4 1.0 0.4 13.0 1.1 1.2 0.8 0.2 0.0 27.2 2.9 2.9 1.0 0.4 2.1 0.0 1.0 0.0 0.0 2.3 0.3 7.7 8.7 2.0 7.4 513.4 0.0 77.4 0.7 0.1 1.3 0.0 0.7 0.7 0.2 0.3 0.0 173.4 5.9 4.4 0.2 0.1 0.0 111.5 0.0 2.0 7.8 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.1 0.6 96.4 0.8 0.2 0.2 0.6 2.4 0.1 0.1 0.0 29.7 0.1 0.0 0.1 0.7 0.0 0.0 0.4 12.1 0.1 0.0 0.3 0.3 0.4 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.3 0.7 1.0 0.6 1.5 0.7 0.8 1.9 1.2 1.3 1.0 1.2 1.0 0.0 189.1 85.6 0.0 0.0 0.3 3.0 49.0 0.0 1.4 0.3 0.3 1.6 52.9 121.9 25.8 0.0 0.2 0.0 4.1 0.0 9.3 1.6 35.8 3.3 0.7 3.0 0.0 0.0 0.9 0.0 4.6 0.0 57.1 0.0 0.0 0.4 0.1 2.9 0.0 0.0 1.6 22.4 1.0 1.9 7.4 4.7 3.7 1.8 1.0 4.4 0.0 0.0 0.0 0.0 33.0 214.4 0.0 1.4 3.3 1.7 0.1 54.2 0.6 0.0 0.0 2.8 0.6 0.7 0.5 0.1 0.1 1.3 0.0 3.1 50.8 MSMP "PC-3, PSMP" ENSG00000215183 "Microseminoprotein, prostate associated" Q1L6U9 9 35752990-35756613 "Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.5;choroid plexus: 1.1;pituitary gland: 1.5;placenta: 1.2" "Group enriched" "Detected in some" 50 "Early spermatids: 96.3;Late spermatids: 216.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 85.7;PC-3: 108.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA055174 Uncertain Supported Vesicles,Cytosol "Secreted in other tissues" No No 30000 "Cluster 10: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 34: Spermatids - Unknown function" Vesicles Cytosol "HPA055174: AB_2682726" 0.2 0.0 0.6 0.2 0.3 0.0 0.1 0.4 0.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.0 0.1 0.2 1.5 0.4 0.0 0.0 0.0 1.5 1.2 0.9 0.0 0.1 0.2 0.0 0.0 0.5 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.3 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 85.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.6 0.3 0.4 0.8 0.3 0.3 1.5 0.4 0.9 0.6 0.3 0.4 1.3 0.0 1.1 0.0 1.1 0.4 1.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.0 1.4 96.3 0.6 0.1 3.1 0.0 0.0 0.0 2.0 0.2 0.3 0.0 0.2 0.0 0.5 2.5 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.8 216.6 0.3 0.1 1.8 0.0 0.0 0.4 0.0 0.0 0.0 1.8 0.1 0.7 0.1 1.5 0.0 0.4 0.2 0.5 0.0 0.0 0.1 0.8 0.5 0.0 0.1 0.3 0.2 0.1 0.3 1.3 MTMR2 "CMT4B, KIAA1073" ENSG00000087053 "Myotubularin related protein 2" Q13614 11 95821766-95925315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 120.1;Oligodendrocytes: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049831 Approved Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA049831: AB_2680904" "unprognostic (1.71e-2)" "unprognostic (2.55e-3)" "unprognostic (7.81e-3)" "unprognostic (4.16e-1)" "unprognostic (4.18e-3)" "unprognostic (5.36e-2)" "prognostic unfavorable (1.61e-8)" "unprognostic (3.23e-3)" "unprognostic (3.42e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.60e-4)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (1.54e-1)" "unprognostic (1.50e-1)" "unprognostic (1.14e-1)" "unprognostic (8.03e-3)" 14.7 9.3 11.0 11.2 16.8 4.4 11.8 16.3 18.3 12.2 12.2 12.9 7.1 12.3 6.2 14.7 12.4 14.3 13.5 10.8 14.3 16.4 4.3 12.3 9.5 15.1 14.4 11.5 7.8 12.7 6.4 24.5 15.8 16.1 13.9 18.6 20.5 11.4 6.2 8.2 8.3 18.0 13.5 8.6 13.0 31.0 14.1 15.1 9.9 8.9 12.1 15.2 10.4 22.4 24.1 25.3 54.1 39.2 19.2 29.0 47.5 43.3 37.9 42.4 37.8 57.3 47.1 16.2 50.3 45.5 35.9 30.9 47.7 48.2 38.9 30.8 21.3 31.5 55.0 33.0 42.8 59.3 26.7 24.0 31.2 56.6 54.5 41.8 64.4 35.4 44.7 14.2 39.6 17.9 29.0 27.2 46.6 59.0 34.9 23.2 32.2 16.8 43.9 125.0 35.6 40.6 43.6 36.4 19.2 35.1 27.6 26.5 64.4 47.7 45.1 34.4 41.1 13.1 42.4 14.3 20.4 15.6 50.6 9.8 3.9 1.7 12.4 4.7 13.4 5.8 7.9 15.7 7.6 4.9 4.0 11.3 0.9 14.1 7.2 3.7 8.1 7.8 11.0 16.8 16.3 18.3 10.8 14.3 15.1 14.4 15.8 13.5 14.1 22.4 19.6 3.2 8.6 28.7 9.6 10.3 15.0 9.0 8.6 0.0 8.0 6.7 17.3 0.0 11.6 9.2 0.0 9.0 8.8 9.1 9.8 17.8 74.8 18.1 14.1 20.2 16.2 12.8 69.8 16.9 34.3 17.0 9.7 8.7 19.0 49.1 11.0 1.0 12.5 0.0 37.5 9.8 24.4 10.3 8.2 120.1 11.1 8.3 3.6 40.3 6.8 0.0 14.4 63.8 226.6 17.7 4.7 12.0 7.0 15.1 6.0 29.3 17.0 0.0 32.9 7.9 29.0 46.8 19.2 15.4 6.0 9.0 8.8 12.9 10.6 15.6 MUC5B "MG1, MUC5" ENSG00000117983 "Mucin 5B, oligomeric mucus/gel-forming" Q9HC84 11 1223066-1262172 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "salivary gland: 2621.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 443.2;Distal enterocytes: 158.4;Intestinal goblet cells: 210.1;Undifferentiated cells: 183.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "OE19: 113.9;PC-3: 120.0" "Not detected" "Not detected" "HPA008246, CAB009396" Enhanced Supported Vesicles "Secreted in other tissues" NA NA 1300000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB009396: AB_2282256, HPA008246: AB_1854203" "unprognostic (2.01e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (2.76e-3)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (4.89e-2)" "unprognostic (7.80e-3)" "unprognostic (3.75e-1)" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (8.95e-2)" "unprognostic (2.57e-7)" "unprognostic (2.71e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-1)" "unprognostic (8.13e-2)" 0.1 0.7 0.2 2.0 0.1 0.0 1.3 0.0 0.4 229.4 0.0 58.0 0.1 0.3 0.0 101.0 1.1 221.3 0.1 0.0 0.0 0.1 2.4 7.5 0.0 0.1 0.0 0.1 9.8 0.0 0.4 0.0 0.0 0.6 17.1 0.0 2621.9 0.0 0.3 0.4 2.6 0.6 0.0 0.0 6.9 0.3 0.0 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.1 0.2 0.0 113.9 120.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 2.3 0.0 0.0 6.7 0.6 0.0 6.4 4.3 12.4 443.2 64.0 0.0 0.0 0.1 0.0 158.4 0.0 0.9 0.0 1.4 0.8 0.9 24.5 0.0 0.1 0.0 0.1 1.1 12.8 7.2 4.5 0.0 0.0 1.2 0.2 0.0 0.0 210.1 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 53.4 0.0 1.4 1.3 0.1 0.2 24.5 0.0 0.0 0.0 3.0 0.0 0.5 1.6 0.0 0.1 0.7 0.1 183.1 1.1 MVB12A "FAM125A, FLJ32495" ENSG00000141971 "Multivesicular body subunit 12A" Q96EY5 19 17405722-17433724 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041885, HPA042231" Approved Supported Vesicles NA No "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041885: AB_10964218, HPA042231: AB_10961043" "unprognostic (1.34e-2)" "prognostic favorable (3.26e-4)" "unprognostic (1.48e-1)" "unprognostic (2.35e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-2)" "unprognostic (5.96e-3)" "unprognostic (8.49e-2)" "unprognostic (1.80e-1)" "unprognostic (1.77e-1)" "unprognostic (9.93e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-1)" "unprognostic (2.54e-1)" "unprognostic (2.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.33e-2)" 21.3 28.4 10.5 17.3 11.5 18.2 21.4 11.4 12.3 18.6 11.8 16.7 29.1 17.3 7.4 29.5 22.0 18.7 13.1 10.0 10.3 20.2 19.9 15.5 21.7 14.0 11.0 34.0 20.0 22.2 7.4 19.2 11.6 13.7 11.6 1.2 24.2 17.5 14.4 24.7 22.0 11.6 12.3 22.3 20.9 5.2 11.4 24.0 21.2 12.4 19.3 17.0 18.0 13.5 51.2 23.4 12.1 33.9 15.7 28.8 71.1 18.3 28.4 33.8 40.8 20.1 60.5 32.7 52.7 28.2 28.8 25.5 19.5 35.5 9.0 37.6 60.7 9.5 41.8 44.0 50.3 13.0 29.1 28.2 28.5 29.1 18.0 25.5 40.7 29.9 26.8 65.2 15.6 32.2 24.6 26.2 17.0 40.8 63.9 34.7 14.8 53.1 32.4 21.2 25.3 40.7 19.6 30.2 77.6 10.9 40.1 30.9 21.7 31.5 18.4 35.1 20.5 59.3 72.9 35.0 34.1 49.3 38.9 57.4 61.7 42.9 33.0 66.9 31.0 23.3 34.0 32.0 60.5 29.8 28.0 27.5 36.0 38.2 53.4 53.3 57.2 36.2 10.5 11.5 11.4 12.3 10.0 10.3 14.0 11.0 11.6 12.3 11.4 13.5 67.5 9.6 8.2 5.9 16.4 39.0 41.4 65.1 42.1 5.3 53.6 61.8 5.6 48.6 33.5 46.0 6.2 60.7 18.1 85.0 54.8 78.7 13.5 30.1 26.8 47.7 26.5 8.4 2.2 48.4 99.0 38.6 43.3 30.2 21.6 45.7 62.4 28.0 72.3 3.3 3.2 48.5 50.8 44.9 30.8 16.3 43.5 31.2 32.0 11.2 46.7 32.7 19.6 4.0 7.3 63.4 84.1 47.0 23.5 19.0 104.4 61.3 36.4 13.8 6.6 22.8 40.9 11.8 12.3 58.3 43.9 40.6 21.2 44.3 57.1 45.0 MYCBPAP "AMAP-1, DKFZp434N1415" ENSG00000136449 "MYCBP associated protein" Q8TBZ2 17 50508384-50531501 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 65.1" "Cell type enhanced" "Detected in many" "Early spermatids: 224.2;Late spermatids: 145.2;Respiratory ciliated cells: 40.4;Spermatocytes: 69.9;Theca cells: 54.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 4.4;JURKAT: 3.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA023257, HPA024405" Enhanced Approved Vesicles NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA023257: AB_2671126, HPA024405: " "unprognostic (2.05e-2)" "unprognostic (1.79e-2)" "unprognostic (9.13e-3)" "unprognostic (3.98e-5)" "unprognostic (8.62e-4)" "unprognostic (3.65e-2)" "unprognostic (1.52e-3)" "unprognostic (1.61e-1)" "unprognostic (2.38e-3)" "unprognostic (1.11e-1)" "unprognostic (7.32e-4)" "unprognostic (2.52e-1)" "unprognostic (1.39e-4)" "unprognostic (7.15e-2)" "unprognostic (1.97e-1)" "unprognostic (7.37e-2)" "unprognostic (2.02e-2)" 0.7 0.8 1.7 0.6 1.8 1.3 0.4 2.4 3.4 1.2 3.4 0.4 0.2 0.9 1.1 0.8 5.3 1.0 0.6 1.3 1.0 0.8 0.2 1.5 1.0 2.9 2.4 2.5 0.2 0.4 0.9 0.3 1.4 1.0 0.4 1.1 0.8 1.3 1.1 1.0 0.3 0.9 1.5 0.6 0.4 65.1 1.6 0.9 0.8 0.3 0.6 0.3 0.5 1.1 0.1 0.8 0.3 0.3 0.8 0.4 0.8 0.7 0.3 0.2 0.2 0.4 2.0 0.2 0.1 0.2 0.8 0.3 0.1 0.9 0.2 4.4 0.2 1.3 1.3 0.4 0.7 0.1 0.2 1.2 0.2 0.4 1.8 0.8 0.6 3.8 0.2 0.4 0.6 0.1 0.2 0.3 0.1 0.1 0.5 0.1 0.2 0.2 0.0 0.2 0.6 1.6 0.3 0.2 0.1 0.5 0.3 0.8 2.0 0.3 0.4 0.1 0.1 2.3 0.8 0.1 0.5 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 1.7 1.8 2.4 3.4 1.3 1.0 2.9 2.4 1.4 1.5 1.6 1.1 0.3 0.0 1.7 7.2 0.7 0.1 1.4 0.7 0.0 3.6 0.4 0.3 0.9 0.0 6.5 1.8 0.0 2.4 1.7 0.4 0.0 0.1 224.2 18.6 1.2 1.1 0.0 3.6 2.5 0.4 0.3 2.0 0.0 0.6 0.0 5.6 0.0 0.0 0.4 0.0 2.2 1.8 0.0 0.6 0.5 145.2 6.8 0.6 0.0 2.8 0.0 4.3 3.1 0.5 1.0 0.1 0.1 3.8 0.6 1.1 1.4 0.2 40.4 0.5 0.0 2.7 1.4 69.9 7.6 0.1 0.4 0.1 1.4 54.9 0.4 0.8 MYOF "FER1L3, KIAA1207" ENSG00000138119 Myoferlin Q9NZM1 10 93306429-93482334 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 123.4;Pancreatic endocrine cells: 153.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 20.4;non-classical monocyte: 26.6" "Group enriched" "Detected in many" 57 "dendritic cells: 8.1;monocytes: 26.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 452.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014245 Enhanced Supported "Vesicles,Plasma membrane" NA NA 190000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "Plasma membrane" "HPA014245: AB_1848495" "unprognostic (3.41e-2)" "unprognostic (3.85e-1)" "unprognostic (2.88e-2)" "unprognostic (7.44e-2)" "unprognostic (3.50e-2)" "unprognostic (8.57e-3)" "unprognostic (3.48e-2)" "unprognostic (7.75e-2)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.55e-1)" "unprognostic (5.74e-3)" "unprognostic (1.87e-1)" "unprognostic (1.94e-2)" "unprognostic (9.17e-2)" "unprognostic (9.18e-2)" 31.7 8.1 2.9 20.6 4.1 1.5 43.3 5.0 2.5 56.4 37.4 22.4 5.3 27.5 7.1 36.4 36.9 26.6 13.8 3.4 4.1 10.9 2.9 32.2 4.4 8.9 6.8 9.8 5.9 23.8 3.8 55.2 8.1 27.5 29.3 0.9 19.7 31.4 3.6 56.1 9.0 44.3 6.2 6.5 13.4 2.2 5.4 5.1 35.7 6.2 9.1 62.0 29.4 6.2 228.9 206.3 21.4 14.6 159.4 318.4 62.0 190.3 452.7 110.1 109.2 51.1 177.1 0.0 76.9 353.7 116.2 350.0 1.8 204.7 82.6 1.4 0.9 0.0 80.8 2.1 55.2 0.0 0.2 183.0 71.6 77.7 323.8 289.4 299.7 0.0 0.0 0.5 275.6 39.4 0.1 0.9 1.6 72.0 171.6 0.0 15.8 0.1 314.3 281.5 0.1 0.0 130.4 29.7 46.1 83.1 141.5 4.7 378.5 167.3 11.8 111.3 113.9 0.2 0.3 0.3 128.2 2.6 201.0 0.0 5.4 0.0 0.0 20.4 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.3 0.0 26.6 2.8 0.2 1.6 2.9 4.1 5.0 2.5 3.4 4.1 8.9 6.8 8.1 6.2 5.4 6.2 42.5 60.9 52.5 1.6 1.2 23.7 63.0 101.4 39.3 0.1 48.4 34.3 9.2 14.3 91.5 22.0 0.0 56.6 3.8 74.1 1.9 54.8 0.6 50.9 45.9 28.8 1.8 0.0 2.7 33.7 23.7 38.1 23.0 123.4 1.3 1.7 35.7 0.4 22.9 0.0 0.8 29.6 42.7 29.2 20.2 0.6 5.9 28.5 8.8 60.0 12.8 0.1 0.0 2.0 0.7 153.7 22.2 9.1 0.8 86.7 0.6 1.5 60.7 0.8 6.6 15.9 39.6 0.1 0.3 53.4 30.7 51.2 1.9 8.3 18.7 100.7 NADSYN1 FLJ10631 ENSG00000172890 "NAD synthetase 1" Q6IA69 11 71453109-71524107 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017798, HPA038523, HPA038524" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Vesicles "Golgi apparatus, Cytosol" "CAB017798: , HPA038523: AB_2676060, HPA038524: AB_2676061" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" "unprognostic (7.30e-2)" "unprognostic (2.63e-3)" "unprognostic (1.75e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.17e-6)" "unprognostic (1.19e-2)" "unprognostic (4.38e-2)" "unprognostic (1.41e-1)" "unprognostic (9.41e-2)" "unprognostic (1.99e-2)" "prognostic unfavorable (8.72e-5)" "unprognostic (4.12e-3)" "unprognostic (1.38e-1)" "unprognostic (1.54e-2)" "prognostic favorable (5.10e-4)" 29.5 34.1 18.8 24.1 20.4 67.6 26.2 18.5 21.2 30.4 20.3 48.6 39.5 26.0 24.2 56.3 31.2 25.8 20.3 17.8 18.3 33.2 49.8 35.3 33.3 22.4 19.6 27.6 29.5 13.4 36.0 16.5 21.0 45.3 36.0 6.9 32.9 22.8 11.0 31.1 51.1 19.3 18.8 58.4 34.3 25.6 21.7 27.9 31.8 5.1 28.2 43.4 33.4 24.4 15.9 37.8 12.0 21.6 35.0 50.6 32.4 29.7 27.2 15.4 17.0 32.4 25.7 13.4 33.1 35.3 20.7 55.2 15.9 42.6 8.2 27.9 12.8 22.2 27.6 36.3 43.3 45.1 40.9 72.0 65.8 19.9 17.8 34.9 54.6 24.2 11.9 18.5 21.9 49.7 22.4 29.9 7.0 69.6 21.3 27.5 37.2 13.5 37.8 72.1 8.9 12.7 21.2 27.9 56.0 17.9 24.9 24.4 66.2 16.7 14.2 30.9 11.8 24.3 11.0 11.7 29.9 25.6 12.0 6.1 28.0 17.3 15.3 25.0 12.7 12.2 13.5 13.8 31.1 9.2 8.8 11.4 17.7 16.3 22.6 23.0 17.7 21.4 18.8 20.4 18.5 21.2 17.8 18.3 22.4 19.6 21.0 18.8 21.7 24.4 12.6 22.4 32.3 4.2 24.0 6.2 17.8 18.4 26.2 7.8 13.5 10.9 8.3 12.8 19.8 11.0 4.2 17.4 27.3 65.3 3.9 16.5 22.6 21.1 11.1 15.6 23.4 20.2 5.1 17.3 14.5 12.8 51.0 19.7 22.1 23.1 13.9 16.7 20.1 13.5 5.8 30.3 16.2 23.2 18.5 60.9 9.3 25.4 8.8 8.4 25.8 5.9 29.9 7.5 18.5 20.0 55.8 10.1 18.0 17.9 73.3 16.2 16.5 7.3 13.1 9.6 9.8 15.9 5.0 38.3 12.8 17.2 22.3 17.1 43.7 24.2 NBR1 "1A1-3B, CA125, KIAA0049, M17S2" ENSG00000188554 "NBR1 autophagy cargo receptor" Q14596 17 43170481-43211689 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 276.9;Late spermatids: 909.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022944, HPA022999, HPA023999" Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "Nucleoplasm, Nuclear bodies" "HPA022944: AB_2671001, HPA022999: AB_1859532, HPA023999: AB_1859533" "unprognostic (1.85e-1)" "unprognostic (1.78e-1)" "unprognostic (3.26e-2)" "unprognostic (3.28e-2)" "unprognostic (3.27e-1)" "unprognostic (1.58e-1)" "unprognostic (1.15e-1)" "unprognostic (2.98e-1)" "unprognostic (2.18e-1)" "unprognostic (1.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-2)" "prognostic favorable (2.00e-5)" "unprognostic (1.65e-1)" "unprognostic (4.88e-2)" "unprognostic (2.10e-1)" "unprognostic (1.39e-1)" 45.7 52.3 48.4 39.4 54.5 20.1 55.9 52.1 48.2 52.0 51.2 66.2 70.1 48.9 39.9 40.3 53.4 44.5 67.3 43.7 49.9 84.7 91.3 47.3 41.0 52.2 50.4 69.7 43.9 97.1 28.8 60.1 52.9 64.7 70.4 80.1 49.4 52.0 112.2 42.9 73.8 49.3 52.1 53.0 52.6 141.0 51.6 59.0 68.2 116.0 45.4 47.3 34.5 65.2 42.3 49.8 42.6 44.6 93.5 95.2 41.0 77.1 147.2 60.5 50.4 26.6 65.1 22.7 77.8 105.1 62.6 46.1 48.5 97.4 90.3 70.0 51.2 27.1 62.0 60.0 89.4 23.2 40.1 108.4 111.6 67.2 133.7 127.3 96.0 50.8 58.1 58.7 83.7 23.9 48.9 17.7 13.6 50.0 32.8 16.5 65.6 73.3 81.6 48.0 25.9 45.8 53.1 26.1 79.8 70.7 70.7 38.0 82.2 89.9 34.1 42.7 31.5 69.9 61.8 29.1 61.8 31.5 63.6 41.6 25.7 40.1 20.3 23.3 20.7 13.7 18.1 19.6 19.3 9.4 17.0 16.6 34.4 24.3 36.4 12.0 26.4 25.0 48.4 54.5 52.1 48.2 43.7 49.9 52.2 50.4 52.9 52.1 51.6 65.2 36.9 41.7 44.1 24.5 21.9 23.8 29.2 28.1 54.1 37.3 33.8 27.4 86.4 35.8 40.4 36.8 39.6 28.0 34.6 94.2 19.6 25.4 276.9 40.5 30.4 39.0 40.2 53.2 24.7 21.9 19.4 37.6 31.1 33.0 25.9 53.1 45.3 67.8 22.0 20.2 28.2 56.4 20.3 62.9 19.9 909.9 58.7 35.7 26.6 29.0 35.6 49.3 44.3 33.2 41.4 25.8 64.5 44.4 26.1 41.1 100.3 57.4 63.4 56.9 39.5 33.9 36.2 49.6 30.9 26.7 27.3 15.7 31.9 68.6 52.4 38.7 NDFIP2 "KIAA1165, N4wbp5a" ENSG00000102471 "Nedd4 family interacting protein 2" Q9NV92 13 79481124-79556075 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 342.7;Late spermatids: 290.4;Suprabasal keratinocytes: 367.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 12.1;eosinophil: 22.7;naive CD4 T-cell: 5.6" "Group enriched" "Detected in many" 16 "granulocytes: 22.7;T-cells: 5.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009160 Uncertain Supported Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA009160: AB_1079456" "unprognostic (2.56e-1)" "unprognostic (5.51e-3)" "unprognostic (1.95e-3)" "unprognostic (9.61e-2)" "unprognostic (2.60e-1)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.50e-1)" "unprognostic (5.53e-2)" "unprognostic (2.30e-1)" "unprognostic (3.12e-1)" "unprognostic (1.52e-2)" "unprognostic (2.63e-2)" "prognostic favorable (4.18e-5)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (6.47e-2)" "unprognostic (1.02e-1)" 13.9 19.2 17.0 11.4 20.9 2.6 22.7 10.0 25.2 15.5 7.0 42.7 52.7 10.1 22.5 54.4 17.1 20.1 26.0 27.1 8.1 45.9 46.3 17.7 13.0 10.1 7.3 7.0 31.8 29.6 6.4 31.9 12.3 22.7 47.0 21.7 21.4 15.6 30.9 71.3 64.3 9.1 10.6 11.7 25.9 18.1 9.2 16.0 19.3 19.9 19.6 35.6 25.2 21.5 134.6 22.6 23.2 29.4 27.7 50.3 43.6 48.5 66.9 50.1 83.0 49.9 146.1 5.6 32.6 64.0 28.5 178.2 20.5 84.9 75.3 69.7 57.1 6.2 66.5 27.1 50.5 106.2 17.8 40.4 109.3 33.4 52.7 55.8 24.1 10.4 27.5 10.0 56.8 19.3 8.7 24.1 17.1 109.7 22.7 0.5 45.7 25.2 123.1 76.7 23.3 33.4 54.9 52.4 40.0 37.8 43.8 88.2 20.4 16.0 20.4 31.1 32.8 37.6 44.2 21.1 65.6 0.5 65.6 12.1 0.0 22.7 3.2 0.0 2.7 0.2 2.8 2.6 0.0 0.6 5.6 3.1 0.1 0.8 0.0 0.2 3.2 2.4 17.0 20.9 10.0 25.2 27.1 8.1 10.1 7.3 12.3 10.6 9.2 21.5 17.5 41.7 28.9 26.4 4.4 342.7 137.0 180.6 118.4 30.9 32.7 18.8 29.4 57.2 93.2 47.8 6.2 112.6 6.9 161.0 23.5 85.6 271.2 51.5 17.2 22.0 69.4 4.2 189.0 72.2 152.7 33.2 31.1 49.8 88.2 11.5 20.7 69.2 14.4 16.8 44.2 88.1 95.6 17.0 23.5 290.4 17.4 4.0 33.8 27.2 2.7 22.8 5.2 42.3 100.3 101.7 96.7 12.8 13.8 105.6 204.3 104.6 112.6 15.5 13.1 22.2 24.0 56.5 45.1 102.2 367.7 109.7 24.9 35.2 73.3 145.5 NDNF "C4orf31, FLJ23191" ENSG00000173376 "Neuron derived neurotrophic factor" Q8TB73 4 121035613-121073021 "Disease related genes, Predicted secreted proteins" Neurogenesis "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 106.5;placenta: 60.1;retina: 57.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Bipolar cells: 69.8;Early spermatids: 217.1;Late spermatids: 221.7" "Cancer enriched" "Detected in many" 4 "lung cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 48.5;U-266/70: 20.8;U-266/84: 85.8" "Group enriched" "Detected in all" 4 "basal ganglia: 11.1;olfactory bulb: 34.0" "Low region specificity" "Detected in all" HPA048881 Supported Vesicles "Secreted in other tissues" NA NA "Cluster 19: Lung - Lung function" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA048881: " "unprognostic (2.84e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (3.94e-1)" "unprognostic (6.26e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (6.65e-4)" "unprognostic (2.18e-3)" "unprognostic (6.27e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.38e-3)" "unprognostic (1.20e-1)" "unprognostic (1.18e-4)" "unprognostic (1.74e-1)" 4.8 2.6 1.1 0.9 1.7 0.0 3.2 4.7 1.2 14.2 9.3 6.5 2.9 6.0 4.3 7.7 20.4 9.4 5.2 1.8 2.6 27.1 0.4 106.5 0.3 8.8 12.9 42.5 0.5 0.7 5.3 60.1 15.2 16.7 8.3 57.4 2.2 4.4 4.3 1.7 4.7 3.5 7.6 0.3 4.1 10.4 3.7 2.4 1.3 14.0 0.2 9.0 1.9 5.4 0.2 0.0 10.6 0.0 13.9 11.3 0.2 0.2 0.5 0.2 0.5 1.6 0.0 0.0 0.0 48.5 0.8 0.0 0.0 0.0 1.1 0.9 1.7 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.2 0.6 0.0 0.0 0.0 14.3 1.0 0.0 0.2 0.1 0.9 7.4 2.1 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 2.6 0.2 0.0 0.0 11.5 0.0 0.2 0.5 20.8 85.8 0.0 3.9 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 4.7 1.2 1.8 2.6 8.8 12.9 15.2 7.6 3.7 5.4 10.9 246.8 48.3 1.6 0.0 1.1 0.0 0.0 0.0 69.8 0.2 0.1 1.6 8.6 28.6 12.9 18.8 0.3 0.0 5.3 0.0 0.0 217.1 0.9 4.7 11.7 1.8 0.0 0.0 0.2 0.0 14.9 0.0 0.1 2.5 0.1 2.9 0.0 0.1 1.7 8.0 0.8 0.0 0.0 0.8 221.7 3.4 0.4 5.4 6.5 0.0 12.2 0.0 0.0 0.0 0.1 0.5 0.7 0.0 0.0 0.0 0.0 12.5 20.0 0.0 1.2 3.6 6.4 5.0 0.3 0.9 0.5 0.3 13.0 1.2 0.1 NDP "EVR2, norrin" ENSG00000124479 "Norrin cystine knot growth factor NDP" Q00604 X 43948776-43973395 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision, Wnt signaling pathway" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8;ovary: 46.2" "Group enriched" "Detected in some" 4 "Granulosa cells: 181.3;Muller glia cells: 105.5" "Cancer enriched" "Detected in many" 5 "glioma: 25.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "U-87 MG: 72.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003095 Supported Nucleoplasm,Nucleoli,Vesicles "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA003095: AB_1079457" "unprognostic (1.12e-1)" "unprognostic (7.12e-2)" "unprognostic (2.27e-2)" "unprognostic (2.55e-3)" "unprognostic (6.84e-3)" "unprognostic (1.51e-1)" "unprognostic (9.09e-2)" "unprognostic (2.29e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.47e-1)" "unprognostic (1.13e-1)" "unprognostic (2.87e-3)" 0.5 0.0 31.5 0.0 33.4 0.0 3.3 30.9 35.8 20.9 22.4 0.2 0.1 15.4 22.0 0.0 20.8 0.4 0.3 31.5 29.6 0.1 0.0 0.0 0.2 30.1 33.2 46.2 0.0 0.2 0.1 4.0 31.6 7.1 0.2 19.2 0.1 13.1 0.0 0.6 0.2 11.4 32.4 0.1 0.3 1.0 34.2 0.0 0.2 0.0 0.2 0.5 2.3 32.4 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 1.5 0.0 0.0 0.1 1.9 0.0 0.0 0.0 1.8 0.0 4.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.0 2.2 0.0 0.0 0.0 72.9 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 33.4 30.9 35.8 31.5 29.6 30.1 33.2 31.6 32.4 34.2 32.4 0.0 0.0 0.0 29.0 0.0 0.1 0.0 1.2 0.0 0.6 1.3 0.1 0.3 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 2.0 0.0 9.1 17.7 0.2 0.0 0.0 4.2 0.0 0.3 0.9 0.0 17.0 0.0 181.3 0.0 0.0 0.1 0.0 0.8 0.0 2.0 0.0 0.0 0.7 13.4 0.6 0.0 0.0 0.0 105.5 0.0 1.5 9.5 1.2 0.0 9.8 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 5.4 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 NEU1 NEU ENSG00000204386 "Neuraminidase 1" Q99519 6 31857659-31862905 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 197.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 3.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.0" "Cell line enhanced" "Detected in some" "GAMG: 5.4;U-266/84: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015634, HPA021506" Approved Supported "Vesicles,Cell Junctions" NA NA 180000 "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" Vesicles "Cell Junctions" "HPA015634: AB_1854386, HPA021506: AB_1854385" "unprognostic (3.84e-2)" "unprognostic (7.47e-2)" "unprognostic (9.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-1)" "unprognostic (4.42e-3)" "unprognostic (1.38e-3)" "unprognostic (8.58e-3)" "unprognostic (7.49e-2)" "unprognostic (5.21e-2)" "unprognostic (4.44e-3)" "unprognostic (1.27e-1)" "unprognostic (2.70e-2)" "unprognostic (6.22e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (2.13e-3)" 23.9 57.2 0.7 0.4 0.8 0.0 22.4 2.5 1.2 21.2 1.2 25.1 0.7 19.5 0.0 14.9 16.8 1.0 22.5 0.7 0.6 43.7 29.9 28.9 0.3 0.8 0.5 20.3 35.9 0.3 33.0 0.2 0.8 26.5 0.0 1.6 38.6 0.0 21.3 20.1 24.3 0.1 0.3 25.3 29.8 8.2 1.0 0.0 31.8 0.0 0.0 23.2 16.2 1.7 0.3 0.2 0.8 1.4 1.8 0.4 0.7 0.2 0.2 0.3 0.3 1.5 0.6 0.7 0.4 0.1 5.4 0.3 2.2 0.0 0.4 2.5 0.3 0.6 0.9 1.2 1.4 0.9 1.8 1.0 0.2 1.4 0.7 0.2 0.6 0.9 1.1 1.2 0.5 0.3 0.6 0.0 0.6 0.5 0.4 0.9 0.4 0.9 1.0 0.4 0.7 0.4 0.2 0.3 0.7 0.9 0.9 0.5 0.7 1.1 0.8 0.7 0.6 3.7 9.6 0.9 1.7 0.4 0.4 1.3 0.3 0.4 0.2 0.3 0.1 0.2 0.2 0.1 0.2 0.6 0.2 0.3 3.0 0.3 0.2 0.3 0.2 0.1 0.7 0.8 2.5 1.2 0.7 0.6 0.8 0.5 0.8 0.3 1.0 1.7 65.7 25.6 46.3 5.2 57.0 34.3 48.5 45.0 39.9 26.4 87.7 55.8 29.0 51.5 54.8 47.8 25.0 62.8 100.5 83.7 9.8 114.2 0.8 29.3 53.5 42.8 113.5 4.6 6.3 59.6 57.8 73.8 32.6 60.8 67.9 17.4 30.7 34.5 170.9 10.1 7.6 39.9 79.3 63.0 65.9 1.4 27.7 93.0 71.2 9.4 25.8 48.8 9.2 5.0 4.0 34.4 88.1 23.3 81.7 89.0 115.0 59.9 29.2 32.7 26.3 60.8 43.7 5.4 10.0 29.3 41.6 197.0 81.7 40.3 41.1 34.6 NISCH "I-1, IRAS, KIAA0975" ENSG00000010322 Nischarin Q9Y2I1 3 52455118-52493068 "FDA approved drug targets, Predicted intracellular proteins" Apoptosis Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enteroendocrine cells: 169.3;Peritubular cells: 246.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023189 Approved Approved "Nucleoplasm,Vesicles,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nucleoplasm, Cytosol" "Vesicles, Microtubules, Cytokinetic bridge" "HPA023189: AB_1854495" "unprognostic (6.66e-2)" "unprognostic (1.58e-1)" "unprognostic (1.59e-3)" "unprognostic (4.11e-3)" "unprognostic (1.64e-1)" "unprognostic (8.08e-3)" "unprognostic (1.60e-2)" "unprognostic (6.56e-3)" "unprognostic (4.96e-2)" "unprognostic (8.33e-3)" "prognostic favorable (1.91e-4)" "unprognostic (1.40e-2)" "unprognostic (5.10e-2)" "unprognostic (1.19e-1)" "unprognostic (2.94e-2)" "unprognostic (1.47e-1)" "unprognostic (7.05e-3)" 55.2 69.8 46.5 28.7 55.5 38.7 60.5 78.2 56.6 105.8 22.2 68.5 24.3 76.2 34.0 51.3 72.0 29.9 48.5 56.3 38.7 54.6 45.6 56.2 32.5 20.9 32.6 93.0 54.1 32.5 181.8 39.1 32.9 107.5 20.6 19.0 53.6 51.6 36.3 80.7 55.3 33.0 9.1 54.1 52.7 84.5 35.2 30.1 60.8 16.3 23.3 78.1 71.6 35.2 15.6 16.0 48.8 40.1 35.7 39.2 40.0 32.8 21.5 25.7 26.0 24.2 22.8 21.7 9.0 45.6 21.0 20.4 26.1 35.7 15.1 22.3 28.2 39.2 65.2 23.9 32.4 23.2 33.6 61.9 28.2 27.7 23.5 54.0 42.0 42.4 21.1 23.4 24.3 22.2 41.8 51.2 30.1 19.8 27.1 24.5 13.4 25.4 29.2 30.6 20.6 35.9 35.6 9.3 23.1 42.3 28.9 38.5 46.3 36.0 34.1 36.9 24.1 38.7 23.8 27.3 24.7 37.3 22.4 5.2 4.5 3.5 3.0 4.0 3.1 2.5 2.6 4.0 2.3 2.8 3.1 3.3 1.5 3.2 0.6 3.4 3.0 3.6 46.5 55.5 78.2 56.6 56.3 38.7 20.9 32.6 32.9 9.1 35.2 35.2 26.1 25.6 32.3 34.0 14.9 27.5 14.6 23.3 40.5 40.9 29.2 37.1 20.4 8.6 19.1 14.7 8.4 32.4 24.2 20.5 9.8 12.1 10.3 14.5 26.7 22.1 169.3 4.6 64.9 9.4 14.0 23.4 23.4 18.9 25.3 40.2 46.1 15.3 30.5 28.6 44.0 19.1 22.4 50.5 14.5 25.9 88.3 24.3 19.6 15.0 13.0 12.1 17.5 21.1 26.1 10.0 14.2 246.0 12.4 12.6 16.5 15.6 15.2 22.4 26.3 17.2 24.8 31.2 18.0 16.7 22.3 24.2 18.4 47.6 15.7 11.7 NLRP5 "CLR19.8, MATER, NALP5, PAN11, PYPAF8" ENSG00000171487 "NLR family pyrin domain containing 5" P59047 19 55999726-56061810 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 50 "parathyroid gland: 22.4" "Cell type enhanced" "Detected in some" "Microglial cells: 1.0;Oligodendrocyte precursor cells: 2.0;Oligodendrocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "Karpas-707: 1.3;U-2 OS: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047260, HPA056271" Uncertain Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 9: U-2 OS - Unknown function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Vesicles "HPA047260: , HPA056271: AB_2683083" "unprognostic (9.67e-2)" "unprognostic (2.22e-2)" "unprognostic (5.03e-1)" "unprognostic (7.78e-2)" "unprognostic (1.72e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 22.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NPC1 SLC65A1 ENSG00000141458 "NPC intracellular cholesterol transporter 1" O15118 18 23506184-23586506 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 110.6" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 70.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 273.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026618, CAB070132, HPA077445" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Vesicles" "CAB070132: AB_10001101, HPA026618: AB_1854580, HPA077445: " "unprognostic (1.74e-1)" "unprognostic (1.53e-3)" "unprognostic (2.67e-1)" "unprognostic (1.25e-1)" "unprognostic (3.20e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (2.26e-6)" "unprognostic (1.31e-1)" "unprognostic (1.01e-2)" "unprognostic (7.36e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-3)" "unprognostic (2.78e-2)" "unprognostic (1.89e-1)" "unprognostic (2.73e-2)" "unprognostic (1.38e-1)" "unprognostic (2.08e-3)" 17.5 76.7 35.1 16.9 69.6 42.6 20.0 55.3 47.8 16.7 28.6 13.7 14.5 16.7 15.0 20.5 13.4 15.3 11.5 41.1 44.3 16.8 15.2 29.0 20.4 73.3 55.8 16.0 11.9 72.6 15.0 27.8 66.6 13.1 12.0 28.0 36.8 13.2 22.9 24.3 17.8 15.1 49.8 17.1 20.4 13.7 55.8 12.2 11.8 14.1 15.6 15.8 18.0 110.6 21.5 41.4 17.8 29.3 55.8 44.6 40.7 37.3 81.1 38.8 84.3 28.1 30.7 18.4 28.0 55.0 132.8 59.3 22.6 63.2 35.2 15.0 17.9 6.8 35.7 63.2 79.2 25.0 28.5 42.2 61.3 81.7 273.2 76.8 40.3 20.7 20.1 47.5 44.2 32.4 10.6 14.9 12.5 24.4 37.3 15.3 28.1 45.0 88.8 51.9 7.5 14.5 44.6 62.0 54.3 27.7 15.9 19.5 50.0 81.1 15.3 32.4 32.3 29.7 97.1 12.2 177.7 21.8 37.1 4.4 9.0 8.8 29.7 8.7 20.5 5.0 12.4 20.7 4.0 6.7 5.5 15.0 7.9 10.5 13.8 70.9 17.4 10.6 35.1 69.6 55.3 47.8 41.1 44.3 73.3 55.8 66.6 49.8 55.8 110.6 18.4 25.6 56.1 32.7 9.6 9.3 34.1 16.5 8.0 6.7 10.5 9.4 4.4 11.5 21.8 9.2 18.8 15.1 61.0 24.8 0.0 11.2 1.2 23.3 12.2 16.4 3.6 2.5 23.8 15.1 7.8 13.0 15.3 53.9 10.8 31.6 6.8 9.8 28.9 3.3 20.2 7.3 2.0 11.9 6.5 1.5 9.0 21.0 12.4 59.0 7.2 15.1 25.7 39.2 182.0 34.4 22.6 10.5 15.6 41.5 8.3 5.4 10.0 12.7 0.0 10.3 14.4 13.9 25.1 17.6 14.5 23.8 19.1 52.4 7.6 64.0 NR0B1 "AHC, AHCH, DAX1, DSS" ENSG00000169297 "Nuclear receptor subfamily 0 group B member 1" P51843 X 30304206-30309390 "Cancer-related genes, Disease related genes, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Receptor, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 32.7;testis: 19.3" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 5.4;Ionocytes: 8.2;monocytes: 2.6;Oligodendrocyte precursor cells: 10.6;Theca cells: 4.9" "Cancer enhanced" "Detected in many" "lung cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A549: 62.5;RT4: 19.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA061948, HPA067207" Supported "Nuclear speckles,Vesicles,Centriolar satellite" NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear speckles" "Vesicles, Centriolar satellite" "HPA061948: AB_2732673, HPA067207: AB_2732761" "unprognostic (1.50e-2)" "unprognostic (9.68e-2)" "unprognostic (9.47e-3)" "unprognostic (1.23e-1)" "unprognostic (2.81e-1)" "unprognostic (7.45e-3)" "unprognostic (4.83e-2)" "unprognostic (9.00e-2)" "unprognostic (1.33e-3)" 0.2 32.7 1.4 0.0 1.3 0.0 0.2 1.0 1.5 2.4 0.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 1.4 1.3 3.6 2.1 0.0 2.5 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 1.2 0.1 0.7 19.3 5.9 0.0 0.0 0.0 0.0 0.0 2.0 1.4 0.0 62.5 0.0 0.0 2.3 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 2.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 8.8 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.3 1.0 1.5 1.3 1.8 1.4 1.3 1.3 1.2 5.9 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.1 5.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.3 8.2 0.0 0.0 1.9 1.2 0.1 1.8 0.0 2.6 0.0 0.0 10.6 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.6 0.8 0.0 0.1 0.0 0.0 4.9 0.0 0.1 NTS ENSG00000133636 Neurotensin P30990 12 85874295-85882992 "Predicted secreted proteins" Vasoactive "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 165.8" "Cell type enriched" "Detected in some" 13 "Intestinal goblet cells: 1683.2" "Cancer enhanced" "Detected in many" "lung cancer: 155.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SuSa: 205.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 154.3" "HPA026664, HPA071012" Enhanced Supported Vesicles "Secreted to digestive system" NA NA 1600000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "HPA026664: AB_2671936, HPA071012: " "unprognostic (3.63e-1)" "prognostic favorable (9.94e-5)" "unprognostic (8.18e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.99e-2)" "unprognostic (3.04e-1)" "unprognostic (7.62e-2)" "unprognostic (2.43e-1)" "unprognostic (1.53e-3)" "unprognostic (8.83e-2)" "unprognostic (1.74e-2)" "unprognostic (3.76e-2)" "unprognostic (1.30e-6)" "unprognostic (2.94e-2)" "unprognostic (2.25e-1)" "unprognostic (2.17e-1)" "unprognostic (7.48e-2)" 6.2 1.2 3.3 3.6 0.6 0.0 5.2 0.9 8.4 0.7 0.5 1.8 6.6 0.3 0.7 5.6 0.9 1.3 0.9 2.5 18.1 1.7 1.4 1.2 11.7 11.7 10.2 0.6 0.4 0.1 32.3 0.5 6.2 0.3 1.5 0.0 0.1 0.6 0.0 0.2 165.8 1.1 3.2 0.1 36.4 0.3 26.8 0.5 0.8 0.2 1.0 3.1 0.3 3.6 0.0 5.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 0.0 0.0 0.0 0.0 1.0 50.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 10.7 0.0 4.1 0.0 1.7 0.0 0.0 0.0 5.4 1.6 0.0 0.0 0.0 205.5 0.4 0.0 0.0 0.1 0.0 0.4 0.0 2.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.6 0.9 8.4 2.5 18.1 11.7 10.2 6.2 3.2 26.8 3.6 3.6 0.0 0.5 0.0 0.0 1.3 0.7 22.6 0.0 0.0 10.1 0.0 0.3 0.0 27.0 9.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.4 2.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 44.3 0.0 0.2 0.0 1.2 1683.2 2.0 0.3 2.6 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.5 15.0 0.0 0.0 2.5 120.8 0.0 3.5 0.0 0.0 0.0 0.9 0.8 0.1 1.2 2.3 0.1 1.3 0.0 8.1 60.4 OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 136.6;Fibroblasts: 246.9;Leydig cells: 73.3;Theca cells: 126.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 577.3;ASC TERT1: 312.6;BJ hTERT+: 374.8;HSkMC: 581.6;LHCN-M2: 602.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" NA NA 3000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA027991: AB_2732440" "unprognostic (1.04e-1)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.80e-3)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "unprognostic (4.41e-3)" 85.6 42.6 5.7 24.9 7.4 0.9 89.7 7.2 12.4 170.6 8.2 71.9 15.1 124.7 42.6 26.6 96.3 95.0 56.6 5.4 6.7 34.1 36.3 55.4 12.0 9.8 7.7 177.4 35.2 9.9 17.9 111.8 8.6 42.9 34.5 0.2 16.7 73.8 10.3 37.6 32.3 94.6 9.2 9.9 48.4 9.3 9.7 8.9 21.8 38.2 14.9 71.1 98.8 11.2 0.0 19.7 9.7 0.1 577.3 312.6 0.6 77.1 374.8 26.5 85.3 25.2 0.2 0.0 4.1 222.4 0.2 0.0 3.2 0.3 4.0 0.0 0.0 0.0 0.1 19.3 149.6 0.2 0.0 581.6 0.0 37.2 0.5 10.7 2.1 0.0 0.0 0.1 602.3 0.3 0.2 0.4 45.8 0.0 0.7 0.1 142.6 0.3 0.0 0.0 0.3 5.4 0.1 0.2 10.5 143.3 224.6 0.9 1.8 14.9 27.6 5.9 0.0 0.2 0.1 0.0 7.3 0.0 94.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 7.4 7.2 12.4 5.4 6.7 9.8 7.7 8.6 9.2 9.7 11.2 13.6 0.0 3.7 0.0 0.4 13.0 0.2 0.0 0.6 0.0 2.1 2.9 1.4 4.3 0.8 1.8 0.0 6.8 1.1 0.2 0.0 0.8 2.9 6.2 136.6 9.5 6.0 0.0 0.0 0.0 4.9 246.9 5.6 3.5 1.3 0.3 45.7 0.5 33.3 0.0 0.0 0.6 0.0 5.9 22.7 1.7 73.3 15.5 12.4 16.9 0.6 0.0 0.0 0.0 0.1 0.3 0.1 33.1 0.2 0.7 0.0 0.5 0.0 0.1 0.0 44.8 28.0 0.3 0.4 1.2 11.5 12.4 2.6 126.1 0.2 0.2 OSBPL9 ENSG00000117859 "Oxysterol binding protein like 9" Q96SU4 1 51577179-51798427 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 216.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027378, HPA027397" Supported Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA027378: AB_1854816, HPA027397: AB_1854817" "unprognostic (5.99e-2)" "unprognostic (1.93e-2)" "unprognostic (1.22e-2)" "unprognostic (2.43e-3)" "unprognostic (3.11e-1)" "unprognostic (6.72e-2)" "unprognostic (2.85e-2)" "unprognostic (2.47e-1)" "unprognostic (4.17e-3)" "unprognostic (1.58e-1)" "unprognostic (8.36e-3)" "unprognostic (8.61e-2)" "unprognostic (3.64e-2)" "unprognostic (7.53e-3)" "unprognostic (2.55e-1)" "unprognostic (4.95e-2)" "unprognostic (3.37e-1)" 27.5 38.1 17.9 18.1 23.8 30.1 32.6 26.3 23.5 25.5 28.3 20.8 17.4 31.1 31.0 17.7 23.3 17.6 37.0 17.6 23.9 42.8 60.8 27.5 25.9 25.0 21.8 30.5 33.3 60.0 21.1 21.8 26.6 27.8 19.1 53.5 22.0 22.4 70.0 19.6 21.7 24.2 23.0 27.2 34.3 28.4 22.2 21.8 24.7 35.2 33.0 23.7 24.7 32.2 66.3 31.7 69.0 11.2 38.1 17.9 90.7 30.1 50.8 54.9 60.0 53.0 46.6 105.8 54.4 34.1 120.9 26.9 59.2 57.4 76.9 71.9 41.9 77.4 62.7 104.7 36.9 81.7 35.5 44.7 55.0 56.8 31.4 66.8 68.9 52.1 154.4 31.1 26.7 45.4 20.3 92.5 97.0 26.8 15.1 58.2 102.8 110.5 74.0 47.4 31.8 45.2 22.4 79.6 93.7 154.7 38.0 82.8 22.9 11.6 51.2 17.2 58.1 80.2 52.5 120.4 39.3 32.8 23.0 52.7 12.2 30.5 20.1 9.9 28.9 32.6 19.7 20.8 25.0 23.9 21.0 22.2 16.9 16.3 9.4 23.2 20.5 16.4 17.9 23.8 26.3 23.5 17.6 23.9 25.0 21.8 26.6 23.0 22.2 32.2 32.5 80.1 56.8 75.4 39.2 17.7 33.8 25.7 34.1 102.0 34.2 33.0 47.9 38.6 50.5 46.0 41.7 89.2 30.4 20.5 125.2 47.6 40.7 36.3 46.3 30.1 29.8 35.7 64.8 47.8 50.2 48.6 54.0 52.9 33.6 75.7 18.2 61.7 40.1 26.9 113.0 18.3 38.7 22.7 16.0 38.3 62.4 25.3 65.8 63.7 50.1 43.8 29.9 62.8 216.4 41.9 14.3 50.0 81.4 38.5 26.4 59.7 32.1 35.3 46.0 36.9 62.9 32.3 18.9 26.9 18.9 75.5 32.0 52.2 21.2 27.4 OSTM1 "GL, HSPC019" ENSG00000081087 "Osteoclastogenesis associated transmembrane protein 1" Q86WC4 6 108041409-108165854 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Osteopetrosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Melanocytes: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010851 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No 210000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Vesicles" "HPA010851: AB_1079533" "prognostic unfavorable (4.36e-4)" "unprognostic (4.03e-2)" "unprognostic (2.81e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" "unprognostic (1.72e-3)" "prognostic unfavorable (4.26e-4)" "unprognostic (9.40e-2)" "unprognostic (2.56e-1)" "unprognostic (2.25e-1)" "unprognostic (4.06e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (1.34e-6)" "prognostic unfavorable (1.20e-4)" "unprognostic (2.32e-2)" "unprognostic (1.40e-1)" "unprognostic (1.77e-1)" 26.1 19.1 4.7 17.9 5.2 5.7 9.8 5.1 5.8 10.4 33.1 12.2 7.9 13.7 9.0 12.7 9.5 12.5 19.2 5.3 9.2 15.6 13.1 16.2 14.7 6.0 7.6 7.5 5.8 15.3 8.3 14.1 7.9 13.8 11.1 17.6 8.9 16.7 11.8 9.8 9.0 23.3 5.3 18.3 8.5 10.1 7.4 13.7 10.7 11.5 13.5 16.9 7.0 8.3 6.0 17.2 20.1 29.4 59.0 19.0 28.6 42.8 42.7 30.7 50.4 10.0 9.8 13.7 34.4 30.0 82.5 11.1 20.2 14.6 47.0 31.6 15.7 28.9 10.9 12.8 45.6 32.1 64.6 28.1 35.7 37.7 30.0 28.2 15.8 15.2 23.3 48.7 50.3 8.4 7.1 7.3 8.0 7.1 13.0 11.4 29.1 7.5 22.0 15.7 2.2 11.8 34.7 8.7 79.9 26.6 10.0 45.8 19.3 26.7 9.8 59.7 61.4 18.6 34.4 11.9 78.9 21.3 60.3 31.4 20.2 22.8 20.3 29.4 21.5 14.7 16.9 22.3 17.8 8.6 15.6 19.8 29.8 22.0 43.5 12.9 22.6 27.0 4.7 5.2 5.1 5.8 5.3 9.2 6.0 7.6 7.9 5.3 7.4 8.3 28.5 9.6 19.0 26.4 26.0 46.7 19.8 11.7 21.6 28.3 10.0 7.0 24.8 12.8 9.4 12.9 10.4 21.7 32.3 21.9 1.9 12.4 12.0 7.5 15.7 20.7 4.2 4.6 36.6 22.9 33.9 24.4 15.8 9.6 24.1 6.9 26.7 13.2 52.8 28.6 40.1 5.8 6.1 46.5 29.5 5.4 14.3 43.1 151.2 20.6 25.6 23.7 40.2 21.1 36.6 16.8 17.0 28.6 25.0 17.9 7.6 25.5 9.8 17.5 26.3 18.5 29.6 28.0 18.7 12.4 31.1 61.2 29.5 23.7 3.3 16.0 OTX2 ENSG00000165588 "Orthodenticle homeobox 2" P32243 14 56799905-56816693 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "choroid plexus: 108.8;retina: 279.9" "Group enriched" "Detected in some" 11 "Bipolar cells: 170.6;Cone photoreceptor cells: 168.9;Rod photoreceptor cells: 202.5" "Cancer enriched" "Detected in single" 27 "testis cancer: 11.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 249.6;hTERT-RPE1: 57.0;NTERA-2: 199.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA000633, HPA001123" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Vesicles "HPA000633: AB_1079538, HPA001123: " "unprognostic (3.82e-1)" "unprognostic (2.56e-2)" "unprognostic (9.28e-2)" 0.0 0.0 4.1 0.0 1.3 0.0 0.0 8.5 0.5 0.0 108.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.9 2.6 0.0 0.0 0.0 0.0 0.2 8.7 0.0 0.0 0.0 2.5 0.0 2.0 0.0 0.0 279.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 12.8 0.0 0.0 0.8 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 249.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 57.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 199.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 1.3 8.5 0.5 5.9 2.6 0.2 8.7 2.0 0.1 12.8 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 170.6 0.0 0.0 0.3 0.0 0.0 0.0 168.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 202.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OVGP1 "CHIT5, MUC9" ENSG00000085465 "Oviductal glycoprotein 1" Q12889 1 111414319-111427735 "Plasma proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 134 "fallopian tube: 2071.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 9.7;Excitatory neurons: 10.4;Glandular and luminal cells: 12.0;Inhibitory neurons: 8.5;Syncytiotrophoblasts: 17.4" "Group enriched" "Detected in many" 13 "endometrial cancer: 58.7;ovarian cancer: 27.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 4.9;OE19: 6.4;SK-BR-3: 5.0" "Region enhanced" "Detected in many" "cerebellum: 5.9" "Not detected" "Not detected" "HPA031666, HPA062205" Enhanced Supported Vesicles,Microtubules "Secreted in female reproductive system" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles Microtubules "HPA031666: , HPA062205: AB_2684710" "unprognostic (1.52e-1)" "unprognostic (2.06e-2)" "unprognostic (3.35e-2)" "prognostic favorable (1.36e-4)" "unprognostic (8.39e-2)" "unprognostic (3.58e-2)" "unprognostic (2.33e-2)" "unprognostic (3.34e-2)" "unprognostic (5.44e-2)" "unprognostic (3.82e-2)" "unprognostic (7.68e-3)" "unprognostic (2.58e-1)" "unprognostic (5.35e-3)" "unprognostic (2.39e-1)" "unprognostic (1.38e-1)" "unprognostic (3.86e-3)" "prognostic favorable (3.93e-5)" 4.1 1.6 7.6 1.1 7.8 1.9 3.5 8.0 10.6 3.8 5.8 3.4 1.1 15.4 5.1 3.0 2071.7 1.1 2.3 7.7 7.0 5.0 8.0 3.9 2.2 7.3 6.9 6.7 1.5 6.8 2.4 2.0 7.2 5.5 2.2 4.3 4.2 1.5 2.6 7.6 5.2 1.4 6.5 4.6 2.8 9.2 6.9 1.2 2.4 1.0 2.0 4.6 3.8 8.2 0.4 0.4 0.9 0.5 1.8 2.0 1.7 0.2 1.4 0.3 0.7 0.6 0.0 0.8 1.7 0.6 0.0 0.5 0.3 0.3 0.5 2.0 4.9 0.3 0.8 2.4 0.6 0.9 2.2 1.8 2.9 0.0 1.0 1.4 0.4 3.2 0.3 1.5 0.1 0.5 0.6 1.2 0.2 6.4 1.7 0.6 0.2 0.7 1.4 3.7 0.6 0.6 0.1 5.0 0.7 2.4 0.3 0.8 0.8 0.1 0.2 2.5 0.7 1.8 0.5 0.4 0.2 1.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.6 7.8 8.0 10.6 7.7 7.0 7.3 6.9 7.2 6.5 6.9 8.2 1.2 0.0 1.1 3.3 0.6 3.1 1.1 0.3 0.0 2.1 1.7 1.9 0.6 0.0 0.5 0.0 0.0 5.6 0.2 1.1 1.9 0.2 4.0 9.7 0.7 1.6 0.0 0.0 10.4 0.0 2.6 0.6 0.0 12.0 0.0 1.0 1.4 2.9 0.6 0.0 8.5 1.5 2.0 0.6 1.4 6.1 1.5 0.5 0.0 3.7 0.0 0.4 0.0 1.5 2.4 0.2 0.5 1.9 0.1 1.6 0.6 2.8 1.3 0.6 0.0 0.7 1.1 3.8 0.7 1.0 3.1 17.4 0.8 0.2 1.6 1.6 PACSIN2 SDPII ENSG00000100266 "Protein kinase C and casein kinase substrate in neurons 2" Q9UNF0 22 42835412-43015149 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 95.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049854, HPA056520" Enhanced Supported "Nuclear speckles,Vesicles,Plasma membrane,Cytosol" NA NA 2400000 "Cluster 52: Eosinophils - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles, Vesicles, Cytosol" "Plasma membrane" "HPA049854: AB_2680915, HPA056520: AB_2683163" "unprognostic (5.62e-3)" "unprognostic (1.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.64e-3)" "unprognostic (1.63e-2)" "unprognostic (3.96e-1)" "prognostic unfavorable (7.33e-4)" "unprognostic (4.48e-2)" "unprognostic (3.40e-2)" "unprognostic (2.82e-3)" "unprognostic (3.09e-2)" "unprognostic (1.00e-1)" "prognostic favorable (1.09e-13)" "unprognostic (2.87e-1)" "unprognostic (1.11e-1)" "unprognostic (6.20e-2)" "unprognostic (2.95e-1)" 40.8 74.3 25.7 37.1 29.1 29.3 40.7 34.2 27.3 37.5 32.3 61.7 40.8 39.1 21.2 34.1 35.3 45.3 55.7 27.7 39.2 47.1 41.1 50.9 34.2 40.5 36.8 31.4 162.4 29.4 39.9 34.2 40.8 47.0 41.6 28.2 43.5 27.4 49.8 39.5 38.1 30.4 30.7 35.9 51.5 19.5 32.5 28.7 43.9 42.4 26.4 36.5 34.5 31.1 76.3 78.3 64.6 41.5 32.6 34.6 52.9 67.8 40.7 59.9 49.7 82.1 43.8 35.2 56.1 50.6 40.8 52.8 42.5 72.1 39.3 36.1 42.4 56.8 39.4 117.8 46.1 40.5 118.1 33.4 69.8 79.1 34.3 48.7 49.9 32.1 49.9 24.9 52.2 49.7 43.1 63.3 35.6 110.4 32.7 52.3 96.5 23.8 68.9 44.4 41.9 18.7 81.1 55.2 155.8 41.5 40.1 53.1 74.3 44.5 56.4 50.0 40.5 18.4 27.2 38.4 42.7 35.4 99.1 26.1 18.5 47.4 6.8 32.2 7.3 11.3 7.8 5.8 21.5 11.6 7.6 5.8 95.7 16.8 33.9 7.9 12.1 14.1 25.7 29.1 34.2 27.3 27.7 39.2 40.5 36.8 40.8 30.7 32.5 31.1 31.7 70.5 60.6 20.2 20.6 23.2 43.4 23.9 21.1 15.7 37.4 31.1 26.3 24.3 37.2 46.0 39.6 34.4 19.9 142.6 45.0 80.2 3.6 51.6 31.3 28.6 24.7 12.6 22.7 65.4 29.6 20.9 36.7 57.4 71.0 14.7 16.1 22.3 42.7 6.7 41.0 49.5 30.5 38.5 50.0 6.2 21.8 44.9 83.6 54.4 51.3 8.4 7.2 29.1 19.5 70.9 62.3 23.3 13.1 50.6 32.0 55.0 30.7 24.9 92.1 23.5 82.9 22.6 27.6 22.5 16.9 48.2 19.1 13.8 42.2 30.3 PAIP2 PAIP2A ENSG00000120727 "Poly(A) binding protein interacting protein 2" Q9BPZ3 5 139341587-139369720 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 834.4;Late spermatids: 2779.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035945, CAB037212, HPA056766" Approved Supported Vesicles NA NA 21000 "Cluster 5: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB037212: AB_1841072, HPA035945: AB_10672996, HPA056766: AB_2683231" "unprognostic (1.07e-1)" "unprognostic (1.44e-1)" "unprognostic (1.19e-1)" "unprognostic (5.86e-2)" "unprognostic (7.40e-2)" "unprognostic (3.80e-3)" "unprognostic (7.70e-3)" "unprognostic (8.91e-2)" "unprognostic (4.64e-2)" "unprognostic (2.36e-2)" "unprognostic (2.67e-2)" "unprognostic (3.27e-1)" "unprognostic (2.01e-3)" "unprognostic (2.01e-1)" "unprognostic (2.21e-1)" "unprognostic (3.36e-1)" "unprognostic (6.92e-2)" 103.3 148.6 107.9 77.2 107.9 115.7 90.3 120.0 149.6 77.3 119.9 79.1 44.2 94.1 85.6 68.8 91.6 66.5 173.1 107.8 118.9 104.7 114.2 73.1 109.0 119.5 114.0 112.3 64.2 88.9 96.2 93.7 123.8 84.3 53.9 168.9 92.1 82.4 169.6 48.2 50.0 83.1 119.1 92.1 58.1 169.0 110.0 147.4 74.6 161.9 107.7 81.4 54.3 138.9 91.9 102.7 196.2 118.5 144.0 81.3 95.6 81.9 113.6 104.7 163.6 138.5 86.7 160.7 170.8 62.3 120.1 88.9 173.5 112.5 137.4 155.7 136.4 148.5 145.7 125.8 93.0 92.8 105.4 93.2 92.4 78.5 88.8 112.9 108.7 173.3 143.7 138.6 95.8 121.1 254.3 227.3 118.9 130.5 74.6 140.0 248.1 177.2 84.0 163.2 90.9 165.2 121.2 110.7 251.2 245.4 214.4 192.6 66.9 55.9 67.9 61.3 67.3 200.0 262.6 167.8 98.2 161.6 58.9 569.5 292.2 735.8 286.2 329.3 317.0 378.7 314.7 330.4 292.0 337.7 364.4 356.5 800.5 347.5 380.6 298.7 449.5 577.2 107.9 107.9 120.0 149.6 107.8 118.9 119.5 114.0 123.8 119.1 110.0 138.9 154.8 73.7 87.5 26.4 173.8 159.8 164.3 168.2 79.1 102.4 108.2 98.0 59.7 97.2 100.9 99.3 58.4 198.6 253.1 74.0 170.2 126.4 834.4 228.6 109.2 126.9 97.0 190.0 40.6 115.1 134.1 129.5 38.7 109.0 109.0 108.2 123.1 103.8 142.3 97.6 46.6 57.7 120.1 142.2 196.1 2779.9 160.9 170.6 135.2 29.0 239.2 158.5 247.2 29.7 59.9 122.5 64.7 155.3 146.8 232.8 62.1 256.2 149.4 93.6 170.9 87.7 180.3 432.3 238.1 57.0 208.3 479.7 191.3 145.8 59.5 178.3 PARM1 "Cipar1, DKFZP564O0823, WSC4" ENSG00000169116 "Prostate androgen-regulated mucin-like protein 1" Q6UWI2 4 74933095-75050115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 181.9;Distal enterocytes: 398.3;Intestinal goblet cells: 109.7;Paneth cells: 132.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 56.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 15 "memory B-cell: 8.1;myeloid DC: 4.0;naive B-cell: 5.6" "Group enriched" "Detected in many" 15 "B-cells: 8.1;dendritic cells: 4.0" "Cell line enhanced" "Detected in many" "ASC diff: 44.6;Karpas-707: 44.9;U-266/70: 49.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038236 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles, Cytosol" "HPA038236: AB_10675789" "unprognostic (2.57e-2)" "unprognostic (5.20e-2)" "unprognostic (1.26e-3)" "unprognostic (8.61e-2)" "unprognostic (1.44e-1)" "unprognostic (8.49e-3)" "unprognostic (3.08e-1)" "unprognostic (2.42e-2)" "unprognostic (2.73e-1)" "unprognostic (9.74e-2)" "unprognostic (9.44e-2)" "unprognostic (3.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.23e-1)" 45.1 51.8 4.1 27.7 5.4 0.4 29.3 0.0 19.3 43.3 2.1 91.3 7.0 34.7 14.0 13.5 23.3 28.6 103.6 10.4 26.0 55.9 1.3 33.7 18.2 1.3 3.9 19.6 34.1 73.1 41.0 40.7 21.2 83.8 113.4 6.0 39.4 64.5 21.0 11.1 15.7 48.2 0.0 15.3 13.4 12.0 4.1 17.3 123.7 18.1 20.9 44.9 25.0 0.0 1.1 1.9 1.7 0.0 44.6 0.3 0.2 0.0 0.2 0.0 0.0 3.9 0.3 0.0 0.2 0.0 0.1 0.1 15.1 0.0 0.0 0.2 3.3 0.0 0.0 0.0 7.4 0.0 1.3 1.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 44.9 0.8 0.5 5.2 0.2 4.3 0.0 2.7 0.0 4.1 11.8 0.2 9.5 2.8 0.1 0.1 0.3 0.0 1.8 0.0 0.0 0.0 2.7 2.9 0.3 4.2 49.8 5.1 12.9 4.7 0.0 0.7 0.0 0.1 0.0 0.0 0.3 0.0 8.1 0.0 0.0 4.0 5.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.5 4.1 5.4 0.0 19.3 10.4 26.0 1.3 3.9 21.2 0.0 4.1 0.0 44.8 16.0 84.1 2.9 11.6 3.2 27.2 6.5 4.0 7.0 4.0 3.4 181.9 31.5 10.4 0.0 0.0 0.3 0.1 398.3 3.9 0.5 10.1 3.0 73.5 6.4 19.9 2.7 51.3 49.2 0.7 13.2 2.0 2.8 1.3 61.9 2.9 0.0 1.5 0.0 77.8 109.7 14.2 0.3 34.7 28.6 36.7 4.9 8.8 1.0 0.7 0.1 0.0 6.0 3.6 23.5 132.1 74.4 42.9 32.6 2.5 27.7 7.2 1.7 46.0 5.4 61.5 1.6 3.2 0.3 1.8 0.8 1.9 14.9 81.6 9.1 PCDHB3 PCDH-BETA3 ENSG00000113205 "Protocadherin beta 3" Q9Y5E6 5 141100473-141103827 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.8;Cone photoreceptor cells: 2.1;Endometrial stromal cells: 2.6;Horizontal cells: 8.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 11.3;HAP1: 3.5;SH-SY5Y: 15.2;U-138 MG: 5.3" "Low region specificity" "Detected in all" HPA050296 Uncertain Supported Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050296: AB_2681078" "unprognostic (2.72e-2)" "unprognostic (7.47e-4)" "unprognostic (1.22e-1)" "unprognostic (1.95e-4)" "unprognostic (9.34e-3)" "unprognostic (3.42e-2)" "unprognostic (2.29e-2)" "unprognostic (3.17e-1)" "unprognostic (1.37e-1)" "unprognostic (3.34e-1)" "unprognostic (8.52e-3)" "unprognostic (3.45e-2)" "unprognostic (1.82e-2)" "unprognostic (2.37e-3)" "unprognostic (1.24e-1)" "unprognostic (1.82e-2)" "unprognostic (5.18e-4)" 1.8 1.2 0.4 0.7 1.1 0.0 1.7 0.6 1.5 1.2 0.0 0.9 0.3 1.5 0.7 0.3 0.9 0.8 1.1 1.0 0.2 1.1 0.1 1.1 0.1 0.3 0.5 1.6 1.2 1.7 1.8 0.4 0.1 1.4 0.5 1.0 0.7 0.5 0.7 0.7 0.5 1.0 0.2 0.4 0.5 3.6 0.6 0.0 0.7 0.9 0.1 0.8 0.9 0.8 0.0 0.0 1.1 3.1 1.9 0.3 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.2 1.7 0.0 3.5 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.3 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.6 15.2 0.0 0.1 0.0 0.5 1.9 0.1 0.0 5.3 0.7 0.5 0.3 0.3 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.6 1.5 1.0 0.2 0.3 0.5 0.1 0.2 0.6 0.8 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.9 0.8 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.9 0.3 0.8 0.4 2.6 1.1 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.2 0.0 0.0 1.8 0.0 0.0 8.4 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 1.8 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.5 0.0 0.1 0.0 0.3 0.0 1.7 1.1 1.8 0.7 0.1 0.3 0.0 0.0 0.4 0.0 0.3 PCDHGB2 PCDH-GAMMA-B2 ENSG00000253910 "Protocadherin gamma subfamily B, 2" Q9Y5G2 5 141360042-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.2;Cardiomyocytes: 1.4;Endometrial stromal cells: 1.0;Fibroblasts: 1.2" "Cancer enriched" "Detected in many" 5 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.5;ASC TERT1: 9.8;LHCN-M2: 8.2;REH: 7.8" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077526" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane, Cytosol" Nucleoplasm "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077526: AB_2732350" "unprognostic (7.14e-3)" "unprognostic (8.79e-3)" "unprognostic (3.21e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.67e-4)" "unprognostic (1.10e-2)" "unprognostic (2.19e-4)" "unprognostic (2.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.78e-1)" "unprognostic (1.05e-1)" "unprognostic (8.46e-3)" "unprognostic (4.59e-2)" "unprognostic (2.57e-1)" "unprognostic (3.06e-2)" "unprognostic (1.29e-1)" "unprognostic (3.36e-4)" 1.5 1.0 2.6 0.6 3.6 0.1 1.1 6.3 2.8 2.1 0.0 1.1 0.2 3.0 0.9 0.9 1.6 1.9 1.8 3.1 3.2 0.7 0.7 1.7 0.3 3.7 3.3 2.8 0.8 1.2 0.9 1.1 3.6 1.3 0.8 1.6 0.8 1.2 0.8 0.8 0.5 1.5 3.0 0.6 0.6 0.5 2.2 0.4 0.7 0.9 0.3 0.9 1.1 5.5 0.1 0.3 2.0 0.2 13.5 9.8 0.1 2.1 2.9 0.6 3.2 0.0 0.3 3.7 1.0 1.7 7.1 0.5 0.4 0.3 1.0 0.0 0.2 0.0 0.3 0.4 0.5 0.2 0.2 2.5 0.5 0.2 0.1 4.7 1.7 0.1 0.2 1.2 8.2 0.5 2.9 0.7 0.1 0.9 0.9 7.8 2.6 0.2 0.2 0.3 1.5 1.6 0.2 0.4 0.4 1.5 3.0 0.2 5.9 2.9 0.6 4.4 3.9 0.2 2.2 0.6 3.1 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.6 6.3 2.8 3.1 3.2 3.7 3.3 3.6 3.0 2.2 5.5 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.6 2.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113839-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Sertoli cells: 1288.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC diff: 1350.1;ASC TERT1: 462.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 39000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (8.11e-4)" 171.2 25.1 25.4 27.5 27.2 0.7 106.3 20.5 33.3 155.9 43.5 41.6 11.9 101.1 24.2 24.1 89.6 124.5 75.7 22.1 23.2 49.7 13.4 98.3 27.5 22.1 24.6 105.5 20.8 21.9 23.0 113.3 22.8 56.2 14.1 6.3 34.5 43.3 38.1 65.0 37.9 68.9 19.4 41.4 27.9 18.4 27.7 8.7 66.5 44.1 13.8 58.3 98.6 21.6 0.1 0.3 8.3 0.4 1350.1 462.7 3.0 48.9 202.3 33.5 56.4 5.4 0.0 0.0 6.4 142.0 19.0 0.1 0.1 0.4 15.8 0.0 0.0 0.1 3.3 3.5 190.7 0.0 0.4 210.0 0.0 46.3 0.6 106.6 0.1 0.1 0.1 5.5 5.5 0.0 0.1 0.6 9.0 0.2 0.2 3.7 2.5 0.2 0.0 0.0 0.1 24.8 0.5 0.1 0.0 38.2 0.1 0.6 0.4 53.7 17.2 23.1 2.8 0.4 0.0 0.3 33.4 0.1 1.5 0.0 0.0 0.0 0.9 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.0 0.0 0.2 25.4 27.2 20.5 33.3 22.1 23.2 22.1 24.6 22.8 19.4 27.7 21.6 50.8 0.0 1.1 81.9 0.5 24.0 0.5 0.0 2.2 6.6 1.4 3.3 17.3 1.5 0.0 1.8 4.2 0.6 6.0 0.3 0.0 0.8 1.6 2.8 99.5 32.2 0.0 0.0 7.9 0.0 1.1 123.5 2.0 2.3 0.0 2.5 6.4 1.9 1.5 0.0 1.3 0.7 0.0 0.0 35.6 10.9 165.3 3.1 24.9 45.0 0.7 50.7 23.7 10.1 3.3 0.1 0.1 203.8 2.3 0.7 0.3 0.1 0.7 2.9 1288.5 6.6 288.3 1.9 1.6 0.8 15.3 0.8 4.8 4.0 0.4 1.1 PEF1 PEF1A ENSG00000162517 "Penta-EF-hand domain containing 1" Q9UBV8 1 31629866-31644896 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 182.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061608 Supported Nucleoplasm,Vesicles,Cytosol NA NA 570000 "Cluster 2: Granulocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles, Cytosol" "HPA061608: AB_2684567" "unprognostic (2.92e-2)" "prognostic favorable (3.95e-4)" "unprognostic (1.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.11e-1)" "unprognostic (8.40e-2)" "prognostic unfavorable (2.88e-4)" "unprognostic (5.22e-3)" "unprognostic (1.04e-1)" "unprognostic (2.79e-2)" "unprognostic (1.60e-2)" "unprognostic (2.12e-1)" "unprognostic (1.35e-1)" "unprognostic (8.85e-3)" "unprognostic (2.38e-1)" "unprognostic (1.60e-1)" "unprognostic (2.89e-3)" 57.3 67.1 76.4 28.5 78.6 37.9 56.4 80.1 81.3 56.3 77.8 59.0 31.3 63.3 84.4 62.1 54.6 38.6 63.8 77.9 81.6 69.4 71.3 61.3 38.5 81.9 78.6 50.2 40.9 69.1 52.1 61.4 84.7 59.4 45.1 26.6 39.9 59.1 42.5 85.7 44.0 60.0 79.9 55.9 51.3 40.1 78.9 56.6 110.9 39.3 61.6 61.9 52.2 81.4 56.9 65.0 53.1 41.3 61.2 63.8 51.0 52.8 89.8 124.4 109.0 38.7 83.2 60.2 71.9 118.3 63.9 58.1 103.9 134.5 100.1 76.0 112.6 49.9 49.4 78.6 107.9 49.0 45.3 66.3 152.6 122.0 113.2 79.2 122.2 72.6 52.4 60.6 90.4 67.1 75.6 47.5 74.3 69.7 72.9 72.5 51.7 66.2 98.6 60.8 75.8 43.9 60.2 56.1 81.0 82.9 50.0 35.5 65.7 54.0 46.0 92.7 71.3 38.7 42.2 65.4 67.7 71.8 65.9 147.3 75.6 93.0 90.2 69.4 86.8 70.9 75.5 81.4 77.5 76.4 70.2 70.6 76.2 87.4 67.2 71.4 84.0 104.8 76.4 78.6 80.1 81.3 77.9 81.6 81.9 78.6 84.7 79.9 78.9 81.4 58.2 41.7 37.7 5.9 31.6 36.2 66.6 70.8 29.6 41.2 34.7 36.2 20.4 21.5 35.3 69.9 12.5 160.0 33.9 36.6 113.5 72.0 81.3 17.4 20.0 60.3 44.3 40.0 8.0 61.9 106.1 34.0 21.9 19.8 72.9 34.3 35.3 24.4 61.9 53.8 7.4 49.8 50.8 18.5 21.8 87.5 45.1 27.8 49.8 7.5 81.6 59.6 46.4 6.0 13.8 59.1 44.0 58.6 23.6 65.4 48.9 57.8 23.5 26.5 19.7 25.8 38.8 44.1 44.2 24.6 51.4 182.8 33.6 50.9 39.5 58.3 PEX11B ENSG00000131779 "Peroxisomal biogenesis factor 11 beta" O96011 1 145911350-145918717 "Disease related genes, Predicted membrane proteins" "Peroxisome biogenesis" "Peroxisome biogenesis disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017150, HPA050104" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles Nucleoplasm "HPA017150: , HPA050104: AB_2681017" "unprognostic (4.59e-2)" "unprognostic (3.13e-2)" "unprognostic (1.80e-1)" "unprognostic (2.29e-1)" "unprognostic (3.62e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (2.67e-4)" "prognostic favorable (6.85e-4)" "unprognostic (1.19e-1)" "unprognostic (4.08e-2)" "unprognostic (2.10e-1)" "unprognostic (8.48e-2)" "unprognostic (6.96e-2)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (7.62e-3)" "unprognostic (4.28e-1)" 17.5 25.1 34.7 19.0 35.8 13.3 31.2 32.5 42.5 24.6 33.3 24.9 24.6 23.4 33.1 34.3 25.7 17.0 28.0 36.3 38.1 32.4 27.1 20.1 27.4 33.3 33.0 24.6 27.2 33.5 24.5 23.1 35.1 24.3 27.6 20.2 28.7 25.6 39.8 28.1 25.9 21.0 31.6 27.7 28.3 30.8 34.1 30.2 26.4 34.9 34.7 23.2 22.2 34.2 27.1 24.4 21.0 21.1 48.6 37.9 21.9 26.8 35.3 34.4 26.5 11.3 30.7 25.2 28.1 38.3 16.6 31.9 18.6 40.0 24.0 28.4 14.1 15.6 14.8 29.2 68.3 46.9 27.5 49.9 49.3 23.3 22.8 43.9 44.5 34.8 28.7 40.5 54.7 43.1 35.8 43.5 7.5 57.4 29.5 33.0 31.5 55.5 58.8 19.1 14.7 24.0 20.2 38.4 24.7 20.5 53.2 72.0 39.7 23.1 18.2 30.3 19.8 43.1 54.0 35.1 38.5 26.3 16.0 89.6 64.7 47.3 58.5 60.9 64.8 93.2 67.5 65.4 70.8 84.1 74.7 67.9 32.4 71.1 60.5 94.9 79.6 82.7 34.7 35.8 32.5 42.5 36.3 38.1 33.3 33.0 35.1 31.6 34.1 34.2 5.0 16.0 10.3 9.8 17.0 19.4 9.2 41.3 26.7 8.0 16.8 17.0 12.8 17.2 20.7 40.5 0.0 37.9 19.6 20.2 45.0 13.7 12.2 8.2 7.0 12.3 12.7 14.1 13.0 13.8 13.9 11.1 19.4 7.4 3.8 9.3 18.2 32.9 23.0 5.0 13.5 16.0 20.3 18.3 10.7 21.1 14.0 12.9 21.4 4.7 27.1 12.6 25.7 9.5 12.9 16.0 11.4 19.9 17.4 10.1 20.1 34.5 22.9 5.1 6.6 5.8 10.3 41.1 24.3 34.0 22.0 20.0 13.8 11.6 15.8 9.4 PEX2 "PAF-1, PMP35, PXMP3, RNF72, ZWS3" ENSG00000164751 "Peroxisomal biogenesis factor 2" P28328 8 76980258-77001044 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010983, HPA011410, HPA027729" Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA010983: , HPA011410: AB_1854922, HPA027729: AB_10610416" "unprognostic (6.42e-2)" "unprognostic (2.90e-2)" "unprognostic (4.64e-2)" "unprognostic (2.35e-1)" "unprognostic (9.91e-2)" "unprognostic (2.33e-1)" "unprognostic (6.19e-2)" "unprognostic (2.22e-1)" "unprognostic (3.16e-2)" "unprognostic (1.37e-1)" "unprognostic (2.85e-2)" "unprognostic (2.07e-2)" "unprognostic (9.57e-3)" "unprognostic (2.48e-1)" "unprognostic (9.49e-2)" "unprognostic (3.06e-2)" "unprognostic (1.09e-3)" 39.8 45.9 33.1 33.5 36.6 35.8 53.9 34.2 45.6 40.7 38.6 43.1 39.8 33.3 42.4 32.9 41.8 31.9 39.7 32.1 35.1 53.6 43.7 36.5 39.4 37.3 34.5 33.3 39.0 57.7 27.2 24.7 37.6 44.2 39.6 66.5 50.9 83.4 61.8 24.5 41.0 35.3 37.3 36.5 48.3 22.1 34.5 48.8 53.2 44.6 35.7 35.7 31.3 43.3 88.2 29.3 46.9 47.9 50.7 63.2 24.5 64.4 75.3 49.9 55.2 18.4 76.9 50.2 93.6 59.9 39.7 33.3 33.1 50.1 61.2 93.3 28.5 61.1 26.0 28.3 33.9 51.5 46.5 70.9 43.5 37.8 45.6 77.0 55.3 79.3 34.4 46.7 53.9 26.4 90.4 30.1 27.2 126.4 26.3 16.5 37.4 42.1 59.9 61.6 16.7 43.0 41.9 192.0 36.9 39.8 58.7 36.1 54.7 44.4 58.1 57.7 32.4 86.0 53.8 87.9 56.5 26.7 50.2 179.9 55.6 102.6 57.2 58.0 51.2 46.1 39.6 46.5 46.3 50.5 51.6 49.3 38.6 83.1 67.8 46.8 48.6 71.7 33.1 36.6 34.2 45.6 32.1 35.1 37.3 34.5 37.6 37.3 34.5 43.3 28.0 48.1 25.2 32.3 29.7 18.1 31.0 57.8 28.5 28.9 38.9 33.1 27.2 28.6 38.4 27.6 12.5 42.8 38.3 30.2 133.1 52.3 5.6 36.5 19.9 20.7 28.9 25.6 11.9 49.1 24.8 29.8 20.4 22.2 18.3 20.2 25.7 36.7 26.6 13.5 15.2 37.5 48.8 39.1 22.4 7.3 29.5 26.8 28.4 16.9 36.3 68.4 53.5 31.7 45.9 42.0 28.2 35.7 41.7 36.3 43.3 61.4 36.6 34.4 6.6 34.9 24.6 13.7 20.8 28.6 21.0 34.8 37.6 27.7 30.0 43.0 PEX6 "PAF-2, PXAAA1" ENSG00000124587 "Peroxisomal biogenesis factor 6" Q13608 6 42963865-42979181 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Peroxisome biogenesis" "Amelogenesis imperfecta, Deafness, Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 76.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 78.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025924, HPA074179" Supported Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles" "Nuclear bodies" "HPA025924: AB_1855230, HPA074179: " "unprognostic (7.32e-3)" "unprognostic (2.43e-1)" "unprognostic (1.38e-1)" "unprognostic (9.16e-2)" "unprognostic (9.18e-2)" "unprognostic (3.27e-1)" "unprognostic (8.88e-2)" "unprognostic (5.92e-2)" "unprognostic (3.36e-1)" "unprognostic (7.12e-2)" "unprognostic (7.24e-3)" "unprognostic (5.31e-2)" "unprognostic (3.79e-3)" "unprognostic (1.86e-1)" "unprognostic (1.13e-1)" "unprognostic (1.81e-1)" "unprognostic (1.55e-1)" 11.6 20.5 24.9 9.2 25.2 9.5 12.1 23.9 27.7 19.1 25.5 16.3 9.3 15.5 7.7 16.4 22.7 9.6 18.7 25.1 25.5 16.5 27.7 10.0 14.5 27.2 25.5 26.1 76.2 15.2 24.3 9.6 24.2 21.6 7.8 9.9 14.8 11.4 23.4 14.0 16.3 9.6 23.9 17.5 16.3 16.2 25.1 14.7 19.8 15.0 10.4 17.3 15.7 25.2 35.0 16.4 8.1 30.6 29.6 28.3 8.4 6.0 9.4 4.8 10.0 10.5 10.1 14.1 8.2 14.3 20.5 32.2 28.7 31.1 5.0 27.6 15.2 4.7 24.4 6.2 20.0 4.8 9.4 35.5 35.5 19.9 5.5 39.1 24.7 18.9 25.2 14.1 10.7 3.9 12.7 15.8 10.0 78.8 14.3 26.8 14.3 5.8 12.3 10.0 25.4 11.1 5.6 21.9 32.7 13.1 43.2 21.2 14.0 15.2 2.9 7.5 14.0 21.0 19.8 19.7 5.2 24.6 12.4 1.3 1.3 2.1 1.2 1.1 2.1 1.0 1.8 2.5 1.9 1.9 2.2 2.1 0.8 2.0 0.7 1.0 0.9 1.1 24.9 25.2 23.9 27.7 25.1 25.5 27.2 25.5 24.2 23.9 25.1 25.2 5.6 6.4 2.6 19.9 5.6 5.0 10.2 6.2 10.8 15.2 11.8 12.7 4.1 10.0 5.6 7.3 2.1 11.4 5.4 10.2 13.7 2.8 2.5 17.6 10.6 5.8 5.4 1.7 24.6 1.5 6.7 9.2 11.2 9.1 0.0 19.8 8.6 14.1 5.8 21.9 22.4 8.5 6.1 9.7 3.2 3.6 14.6 5.4 8.8 9.4 4.5 11.8 9.2 13.0 16.6 1.9 10.4 9.4 3.1 6.3 15.1 13.9 14.3 7.0 0.0 13.0 6.6 7.3 2.6 6.3 5.5 7.4 7.8 26.1 10.5 6.6 PEX7 "PTS2R, RD" ENSG00000112357 "Peroxisomal biogenesis factor 7" O00628 6 136822564-136913934 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cataract, Deafness, Disease variant, Ichthyosis, Peroxisome biogenesis disorder, Retinitis pigmentosa, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049202 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Vesicles" "HPA049202: AB_2680674" "unprognostic (1.36e-2)" "unprognostic (2.07e-2)" "prognostic favorable (1.61e-4)" "unprognostic (4.01e-3)" "unprognostic (2.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.46e-1)" "unprognostic (1.71e-2)" "unprognostic (4.87e-2)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (6.88e-2)" "prognostic favorable (1.85e-10)" "unprognostic (3.57e-1)" "unprognostic (1.44e-1)" "unprognostic (2.52e-2)" "unprognostic (2.65e-1)" 5.2 14.8 4.6 2.0 4.8 3.8 11.9 6.0 5.2 6.8 5.1 7.9 5.3 4.2 17.2 7.3 8.7 4.5 11.7 4.2 4.2 15.6 9.1 4.9 3.2 4.3 4.4 5.0 26.9 17.1 6.0 4.1 4.5 10.4 8.4 6.9 10.6 6.4 10.7 11.2 4.7 3.3 4.4 3.3 15.6 10.0 4.7 3.7 11.0 9.8 3.3 5.4 6.7 5.5 4.4 4.3 4.4 6.2 6.6 9.8 2.4 6.1 8.9 7.5 7.4 4.9 6.0 1.5 11.3 8.3 8.5 5.3 3.3 13.8 9.8 5.7 7.5 6.4 4.3 0.9 13.9 8.1 5.3 9.6 13.1 5.4 7.9 8.7 5.4 12.0 13.0 5.2 10.6 13.4 3.5 7.9 5.0 13.9 8.3 4.8 3.4 5.7 17.4 6.4 8.3 10.6 6.5 9.0 8.4 4.9 5.8 7.7 2.5 4.8 1.7 7.3 5.3 6.9 5.1 0.0 4.2 6.4 4.9 2.9 1.3 2.2 0.7 1.0 0.7 1.5 1.3 1.6 2.3 1.0 2.4 1.5 0.9 1.6 1.9 1.8 2.3 0.9 4.6 4.8 6.0 5.2 4.2 4.2 4.3 4.4 4.5 4.4 4.7 5.5 4.9 3.2 9.4 10.7 6.3 12.1 14.9 16.5 9.1 9.1 19.5 13.8 18.7 11.5 14.7 11.0 8.4 19.6 2.3 11.6 60.7 16.5 12.5 18.7 6.4 5.6 10.3 15.8 12.4 22.7 21.0 6.8 10.2 11.1 14.0 7.9 6.1 7.0 12.4 0.0 14.7 21.8 30.5 5.7 6.2 10.2 9.0 6.4 14.2 5.6 11.9 20.8 4.1 17.6 19.9 16.7 13.2 9.8 3.7 16.0 15.0 38.3 16.1 9.9 6.6 5.7 8.2 30.6 16.7 15.4 18.2 17.1 6.6 24.3 17.2 17.4 PIK3C2A PI3K-C2alpha ENSG00000011405 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha" O00443 11 17077730-17207983 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Endocytosis, Exocytosis" "Kinase, Transferase" "Cataract, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 217.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037641, HPA037642" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Vesicles, Cytosol" "HPA037641: AB_10671878, HPA037642: AB_10697081" "unprognostic (2.35e-1)" "unprognostic (2.16e-2)" "unprognostic (3.71e-2)" "unprognostic (1.06e-1)" "unprognostic (1.63e-1)" "unprognostic (6.63e-2)" "unprognostic (2.47e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-2)" "unprognostic (1.86e-2)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.20e-2)" "unprognostic (1.51e-1)" "unprognostic (1.18e-1)" "unprognostic (1.37e-1)" 22.5 13.7 16.3 12.3 25.9 9.4 15.9 22.5 14.6 16.1 17.4 13.2 14.9 18.0 15.7 15.4 14.5 19.0 12.4 10.5 14.0 23.5 15.5 16.6 11.3 16.6 16.1 14.1 12.3 43.6 10.3 23.1 17.0 16.4 13.0 22.4 11.8 14.8 6.4 12.3 11.8 18.3 13.8 13.0 18.0 19.3 19.6 9.4 30.7 12.1 10.9 14.9 12.0 15.8 53.8 24.1 39.6 24.8 28.0 28.3 35.3 33.2 35.7 23.9 33.2 58.9 6.0 15.6 16.2 28.6 39.1 34.8 31.9 25.4 42.1 13.5 27.6 9.8 28.4 23.3 30.6 12.3 14.9 22.2 17.5 23.6 45.8 22.2 57.7 9.9 23.4 14.7 18.6 16.6 6.6 7.7 22.6 30.1 18.5 6.9 41.1 11.0 29.6 47.0 23.2 20.5 50.6 21.4 23.2 33.0 12.7 12.3 72.5 19.1 27.4 50.1 20.4 5.9 14.1 12.8 22.8 11.3 22.6 1.7 1.5 1.1 1.7 1.0 1.1 1.4 1.3 1.3 2.1 1.5 1.7 1.0 2.3 1.8 3.2 1.4 0.9 0.6 16.3 25.9 22.5 14.6 10.5 14.0 16.6 16.1 17.0 13.8 19.6 15.8 93.2 76.9 62.0 217.4 25.0 35.3 26.1 18.7 24.5 49.1 34.7 25.0 29.7 25.8 33.1 36.8 70.9 29.6 29.5 22.6 19.6 19.8 35.9 51.8 35.1 87.6 28.7 11.2 57.0 25.1 17.9 28.6 45.3 72.4 32.2 22.8 106.7 32.4 19.2 35.3 81.1 23.5 18.3 46.3 33.1 18.6 25.7 27.0 19.6 69.3 19.6 73.0 17.5 62.8 79.4 26.1 13.1 31.2 29.9 42.7 15.2 22.4 26.4 40.4 39.5 33.7 35.1 52.6 26.8 23.5 34.0 143.5 25.3 25.1 20.7 37.3 PITPNM1 "DRES9, NIR2, PITPNM, Rd9, RDGB, RDGB1, RDGBA1" ENSG00000110697 "Phosphatidylinositol transfer protein membrane associated 1" O00562 11 67491768-67506263 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Distal enterocytes: 69.9;Endometrial ciliated cells: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 91.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060227 Approved Supported Vesicles,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Vesicles "HPA060227: AB_2684226" "unprognostic (1.13e-1)" "unprognostic (1.90e-1)" "unprognostic (1.69e-2)" "unprognostic (1.71e-1)" "unprognostic (2.83e-2)" "unprognostic (8.68e-2)" "unprognostic (8.16e-2)" "unprognostic (4.55e-2)" "unprognostic (1.77e-1)" "unprognostic (2.26e-2)" "unprognostic (4.61e-1)" "unprognostic (3.27e-2)" "unprognostic (2.32e-2)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (4.62e-2)" "unprognostic (5.69e-2)" 10.6 24.5 19.6 24.3 12.6 26.8 6.4 6.1 23.2 10.7 13.9 14.4 18.7 9.3 2.4 19.5 23.1 9.0 22.3 13.3 23.8 37.8 11.0 16.3 27.6 14.2 31.0 4.0 9.8 10.3 26.7 8.0 13.5 10.4 7.5 40.7 8.7 10.3 6.9 5.0 21.1 5.9 2.3 21.6 16.0 8.8 51.5 17.4 15.7 18.4 17.2 16.2 9.3 5.5 12.7 31.2 18.8 13.9 20.3 12.1 30.5 12.2 21.5 14.8 8.4 28.5 22.6 12.5 28.7 17.5 28.4 32.4 14.5 27.0 4.8 91.0 6.0 17.0 55.8 10.8 16.0 19.4 35.3 15.0 17.0 22.4 14.7 27.4 17.9 18.7 13.2 11.0 12.5 19.1 33.2 45.6 19.3 35.9 13.5 23.7 6.0 17.3 24.4 25.1 18.1 11.5 27.3 37.6 29.6 9.0 7.4 16.9 17.7 26.5 20.1 16.9 8.9 16.0 8.3 11.2 37.1 22.7 10.6 0.0 1.4 0.9 1.1 3.3 1.0 0.7 0.8 1.0 1.0 0.5 0.3 0.8 1.4 0.1 2.7 0.4 0.7 1.1 19.6 12.6 6.1 23.2 13.3 23.8 14.2 31.0 13.5 2.3 51.5 5.5 7.5 3.2 5.8 2.0 10.8 8.2 6.3 9.3 13.6 45.7 5.4 5.2 8.4 5.7 9.7 20.2 64.6 4.6 10.6 69.9 3.9 11.3 6.1 63.3 16.5 4.9 11.4 0.4 5.1 9.3 8.9 4.2 34.7 24.6 2.5 7.1 3.3 3.4 8.4 38.7 6.6 16.8 10.2 13.2 14.0 17.0 2.1 15.2 3.6 10.3 13.5 20.7 3.1 0.5 0.5 15.9 32.7 1.2 7.5 9.8 39.0 18.9 37.8 53.7 0.0 6.3 9.8 1.4 5.5 11.2 3.3 15.2 14.9 1.4 24.0 19.4 PITPNM2 "NIR3, RDGB2, RDGBA2" ENSG00000090975 "Phosphatidylinositol transfer protein membrane associated 2" Q9BZ72 12 122983480-123150015 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "lymphoid tissue: 87.3" "Cell type enhanced" "Detected in many" "Astrocytes: 33.6;Cone photoreceptor cells: 54.2;Excitatory neurons: 51.3;Horizontal cells: 40.4;Inhibitory neurons: 41.3;Late spermatids: 87.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 29.5;JURKAT: 35.6;MOLT-4: 55.0;WM-115: 25.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003414, HPA003978" Approved Supported Vesicles NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA003414: AB_1855410, HPA003978: AB_1855411" "unprognostic (2.43e-1)" "unprognostic (9.29e-2)" "unprognostic (2.00e-1)" "unprognostic (5.39e-2)" "unprognostic (2.14e-1)" "unprognostic (6.76e-2)" "unprognostic (2.26e-2)" "unprognostic (1.08e-1)" "unprognostic (2.55e-1)" "unprognostic (6.44e-2)" "unprognostic (1.03e-1)" "unprognostic (9.28e-2)" "unprognostic (1.50e-3)" "unprognostic (7.66e-2)" "unprognostic (1.16e-1)" "unprognostic (1.19e-2)" "unprognostic (9.99e-2)" 4.6 9.0 11.4 4.6 12.3 5.2 3.7 6.7 15.6 6.1 18.7 5.7 4.7 4.6 3.7 4.7 3.7 2.6 4.9 13.1 1.8 8.7 11.0 6.8 3.2 4.9 3.6 15.3 3.5 6.6 8.4 3.6 1.6 3.5 2.5 15.2 2.4 3.8 5.0 4.1 4.9 5.7 0.4 4.4 4.6 7.3 4.9 87.3 3.7 3.3 1.9 7.0 4.9 3.8 4.6 8.7 2.8 4.1 1.9 3.7 16.8 0.7 1.1 2.3 1.2 3.8 3.7 0.0 3.7 1.5 4.8 12.8 2.3 2.2 0.8 0.3 2.8 29.5 5.7 10.5 1.3 1.1 6.0 1.8 3.8 3.0 2.3 10.8 4.5 35.6 6.8 0.3 2.9 2.9 55.0 6.1 3.2 1.4 3.9 15.7 0.2 11.4 4.1 4.7 2.5 0.9 6.3 5.2 4.1 1.6 1.1 3.1 13.3 3.3 3.7 5.4 5.1 0.8 1.0 20.4 8.2 2.2 25.4 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.2 0.6 0.0 0.2 0.5 0.4 0.0 1.9 0.0 0.0 0.3 0.7 11.4 12.3 6.7 15.6 13.1 1.8 4.9 3.6 1.6 0.4 4.9 3.8 16.2 0.0 5.0 33.6 2.8 3.6 0.7 0.7 2.2 19.6 1.5 1.5 7.3 2.8 1.6 9.2 54.2 1.3 6.3 6.3 1.9 3.3 33.0 3.7 3.6 9.3 0.0 1.7 51.3 4.5 6.5 3.8 2.0 5.2 1.3 0.8 6.4 16.3 0.5 40.4 41.3 3.7 0.0 0.6 1.1 87.7 1.8 3.6 1.8 10.3 1.3 3.7 10.3 22.1 1.8 3.9 0.3 4.9 2.2 1.1 6.1 2.6 0.1 15.8 0.0 2.1 2.5 8.2 4.7 3.6 1.6 3.7 4.8 0.4 2.6 0.6 PLA2G15 "GXVPLA2, LLPL, LYPLA3" ENSG00000103066 "Phospholipase A2 group XV" Q8NCC3 16 68245304-68261058 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 58.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 116.0;Horizontal cells: 38.7;Kupffer cells: 37.1;Syncytiotrophoblasts: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041702, HPA041727" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "HPA041702: AB_10794486, HPA041727: AB_10793931" "unprognostic (3.47e-2)" "unprognostic (9.99e-2)" "unprognostic (1.54e-3)" "unprognostic (6.84e-3)" "unprognostic (1.38e-2)" "unprognostic (1.65e-2)" "unprognostic (4.12e-3)" "unprognostic (3.16e-1)" "unprognostic (2.12e-2)" "unprognostic (1.84e-2)" "unprognostic (2.56e-1)" "unprognostic (9.29e-2)" "unprognostic (2.45e-3)" "unprognostic (2.98e-2)" "unprognostic (5.40e-3)" "unprognostic (6.28e-2)" "unprognostic (3.47e-2)" 15.1 11.5 12.9 7.6 12.5 7.0 9.8 12.8 18.1 6.6 9.2 8.0 6.9 6.2 8.7 6.2 7.4 9.3 35.5 13.1 14.2 33.4 17.3 17.5 13.6 13.1 14.1 7.7 7.4 11.4 11.4 27.3 14.6 8.1 5.9 4.4 9.1 5.7 58.3 13.9 6.5 8.8 12.4 20.3 8.4 10.8 15.9 11.7 13.2 22.4 5.1 8.8 6.4 16.1 10.0 10.0 7.9 25.5 36.7 26.8 19.0 24.6 31.6 35.7 30.2 26.1 18.6 17.4 31.2 34.1 28.5 15.2 8.5 10.4 15.9 6.0 16.4 5.0 10.4 19.0 19.6 4.6 25.0 19.0 11.2 35.2 5.5 44.6 22.5 8.9 7.9 9.8 23.0 21.3 7.2 14.5 5.1 9.4 12.1 9.9 11.3 55.3 17.7 8.7 3.0 5.1 31.2 9.6 19.2 6.6 25.2 23.7 18.8 31.5 15.0 41.1 16.5 34.6 33.5 22.1 28.6 13.8 12.0 19.6 24.1 16.0 4.7 27.5 4.8 5.0 5.2 7.0 14.1 5.3 6.5 5.5 1.0 2.3 32.4 12.2 5.1 14.6 12.9 12.5 12.8 18.1 13.1 14.2 13.1 14.1 14.6 12.4 15.9 16.1 4.4 6.4 3.3 3.6 3.0 4.8 2.4 6.8 2.8 12.1 7.0 6.0 22.5 1.5 5.1 9.2 8.4 20.9 4.9 8.1 5.9 10.1 1.9 4.3 4.8 5.9 0.0 1.7 7.0 7.2 7.6 8.2 8.6 9.0 15.2 6.6 9.3 13.7 116.0 38.7 6.7 8.5 2.0 37.1 6.8 6.1 2.1 21.4 12.4 10.3 7.7 4.4 3.1 5.5 3.9 6.3 5.0 1.5 2.6 2.6 3.0 19.5 2.7 6.1 0.0 5.5 6.7 3.4 2.8 4.1 3.4 50.8 3.9 3.1 4.1 2.0 PLA2G4A "cPLA2-alpha, PLA2G4" ENSG00000116711 "Phospholipase A2 group IVA" P47712 1 186828949-186988981 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Glycerol metabolism, Leukotriene biosynthesis, Lipid biosynthesis, Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 87.2;seminal vesicle: 48.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 33.4;Glandular and luminal cells: 28.1;Microglial cells: 115.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 6.8;eosinophil: 7.8;intermediate monocyte: 8.4;myeloid DC: 7.7;non-classical monocyte: 4.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 7 "dendritic cells: 7.7;granulocytes: 7.8;monocytes: 8.4" "Cell line enhanced" "Detected in many" "HeLa: 52.4;OE19: 84.4;RPMI-8226: 73.4;U-2197: 66.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010050, HPA050062, HPA054206" Approved Supported Vesicles,Cytosol NA NA 35000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Cytosol Vesicles "CAB010050: AB_631312, HPA050062: AB_2681002, HPA054206: AB_2682417" "prognostic favorable (9.07e-4)" "unprognostic (1.18e-1)" "unprognostic (2.03e-1)" "prognostic favorable (2.85e-4)" "unprognostic (5.55e-2)" "unprognostic (1.51e-3)" "unprognostic (2.67e-2)" "unprognostic (2.43e-1)" "unprognostic (2.63e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (2.96e-2)" "unprognostic (8.07e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (4.26e-2)" 9.9 12.7 2.4 6.3 3.4 4.8 6.5 2.8 3.7 14.5 3.2 11.9 11.1 10.2 11.7 7.5 24.9 6.2 6.3 2.4 3.3 10.8 2.1 5.9 5.3 4.4 3.5 6.4 7.6 87.2 2.0 5.8 4.0 8.8 8.1 0.8 6.3 48.3 0.5 9.5 8.2 10.5 4.1 6.6 5.3 2.8 3.1 1.5 2.6 2.1 2.9 29.1 8.4 3.9 0.0 39.7 0.2 0.0 23.8 9.5 0.0 1.5 15.1 1.8 3.2 0.3 15.5 0.0 0.0 0.0 6.8 2.8 24.6 7.4 0.8 12.5 0.6 7.6 52.4 0.0 14.7 11.1 3.8 5.4 5.0 19.5 4.0 2.4 16.5 3.4 16.7 5.9 0.0 0.0 0.0 0.0 2.1 84.4 5.1 0.0 0.0 73.4 0.1 5.4 0.2 0.0 5.9 2.0 7.3 0.7 0.8 15.0 3.3 14.3 1.9 66.3 3.2 2.3 0.0 0.0 5.3 32.4 20.7 0.2 6.8 7.8 0.0 8.4 0.2 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.6 1.1 4.0 3.1 0.0 1.7 2.4 3.4 2.8 3.7 2.4 3.3 4.4 3.5 4.0 4.1 3.1 3.9 0.6 0.0 1.1 0.3 0.2 21.4 4.3 4.6 10.2 0.2 2.9 2.9 2.3 0.0 4.9 0.0 0.0 0.1 3.2 1.6 1.9 2.1 0.9 33.4 1.7 6.6 1.2 3.0 8.1 0.0 0.1 11.2 7.1 28.1 10.8 3.3 1.1 0.2 6.6 0.0 5.8 2.6 2.0 7.9 8.3 1.3 10.5 11.5 5.4 115.2 3.7 0.0 1.0 2.0 0.4 1.7 7.3 14.7 0.0 2.3 2.0 0.3 2.3 0.5 0.0 1.2 5.0 0.6 0.3 5.2 8.9 0.0 1.0 1.2 4.8 13.4 PLEKHM1 KIAA0356 ENSG00000225190 "Pleckstrin homology and RUN domain containing M1" Q9Y4G2 17 45435900-45490749 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 31.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.5" "Cell line enhanced" "Detected in many" "OE19: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025018, HPA039473" Approved Supported Nucleoli,Vesicles NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles Nucleoli "HPA025018: AB_1855465, HPA039473: AB_2676526" "unprognostic (1.52e-1)" "unprognostic (3.13e-2)" "unprognostic (4.29e-2)" "prognostic favorable (1.28e-6)" "unprognostic (8.71e-2)" "unprognostic (3.06e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.20e-2)" "unprognostic (1.88e-1)" "unprognostic (2.93e-2)" "unprognostic (4.02e-1)" "unprognostic (3.93e-2)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (1.60e-1)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" 7.0 6.4 2.9 5.5 2.9 9.7 6.2 3.5 3.8 12.9 3.2 6.5 3.5 5.7 1.0 31.7 5.9 5.3 6.2 2.8 3.1 3.6 3.6 8.8 4.8 3.7 3.1 4.9 6.1 4.4 5.7 2.9 3.2 5.1 3.6 1.6 14.4 0.9 12.3 11.8 6.2 2.0 2.8 6.8 5.6 3.4 3.4 5.4 6.5 7.2 4.8 6.8 13.6 3.7 7.3 11.0 1.7 5.4 8.4 4.8 0.1 3.3 4.9 1.9 2.6 4.2 6.0 5.2 3.4 3.9 14.1 1.7 4.1 1.9 1.6 13.7 3.5 0.0 5.6 6.9 2.0 0.0 4.3 2.2 4.9 0.9 8.0 3.8 10.0 0.0 5.2 6.2 9.1 6.0 5.2 1.1 1.7 26.6 9.0 2.8 5.6 5.3 6.0 16.8 3.2 2.1 3.2 4.5 5.2 4.8 10.1 5.3 19.1 12.7 3.6 5.2 5.9 0.6 6.2 1.8 7.7 2.8 5.8 2.8 1.2 1.0 0.2 0.3 0.0 1.2 0.6 0.2 0.3 0.3 0.2 0.0 6.5 0.7 0.4 0.2 0.5 0.2 2.9 2.9 3.5 3.8 2.8 3.1 3.7 3.1 3.2 2.8 3.4 3.7 12.6 12.8 18.1 7.8 17.5 18.0 18.1 10.3 6.8 10.4 11.7 8.4 8.7 15.7 12.7 12.9 16.7 4.8 24.3 25.6 5.9 8.1 4.3 24.9 11.1 12.1 13.8 10.8 13.5 8.2 4.7 12.1 19.9 27.9 1.3 5.4 12.8 8.1 9.1 16.8 13.3 13.0 4.1 27.9 15.2 2.0 7.2 21.1 7.2 9.4 13.7 7.3 14.4 7.5 20.8 18.3 17.7 7.9 22.9 27.2 8.6 10.5 11.9 8.2 0.0 17.7 7.6 7.6 3.7 10.0 16.3 8.6 18.5 9.3 12.2 43.1 PLIN5 "LSDA5, LSDP5, MLDP, OXPAT" ENSG00000214456 "Perilipin 5" Q00G26 19 4522531-4535224 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 202.0;skeletal muscle: 149.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 47.1;Astrocytes: 53.8;Cardiomyocytes: 39.8;Hepatic stellate cells: 42.1;Hepatocytes: 140.5" "Cancer enhanced" "Detected in many" "liver cancer: 9.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.9" "Lineage enriched" "Detected in single" 20 "granulocytes: 13.9" "Cell line enhanced" "Detected in some" "AN3-CA: 2.3;BEWO: 3.2;RT4: 3.1;SH-SY5Y: 2.8;T-47d: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA077050 Supported "Vesicles,Lipid droplets" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 15: Hepatocytes - Hemostasis" "Vesicles, Lipid droplets" "HPA077050: " "prognostic favorable (7.68e-4)" "unprognostic (1.01e-1)" "unprognostic (4.22e-2)" "prognostic unfavorable (8.56e-4)" "unprognostic (1.24e-2)" "unprognostic (6.06e-3)" "prognostic favorable (2.81e-4)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.63e-1)" "unprognostic (1.54e-1)" "prognostic favorable (1.97e-4)" "unprognostic (3.18e-1)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" "prognostic favorable (2.16e-4)" 41.9 6.4 10.8 3.5 11.2 5.2 29.3 6.9 9.6 7.5 12.8 5.4 1.5 2.7 3.9 3.4 12.6 2.0 62.7 8.5 8.1 30.1 202.0 9.3 0.5 8.4 9.2 90.8 112.2 1.5 18.9 0.2 6.9 17.6 0.6 0.9 61.0 3.9 149.2 8.0 5.3 0.5 6.8 8.2 58.9 3.3 9.4 0.4 9.8 24.7 1.0 11.2 2.7 6.4 0.2 0.1 0.5 2.3 1.7 0.1 3.2 0.1 0.1 0.1 0.0 0.2 0.5 0.1 0.7 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.1 0.1 0.8 1.1 0.4 0.3 0.4 0.4 0.0 0.0 0.0 0.2 0.2 0.1 0.7 0.2 0.1 0.6 0.1 0.4 0.4 0.3 0.3 0.1 0.1 2.1 0.2 3.1 0.3 2.8 0.2 0.4 0.0 0.2 6.3 0.4 0.3 0.3 0.3 0.2 0.2 0.3 0.1 0.1 0.2 0.6 0.1 1.9 0.4 0.8 0.3 0.3 0.2 0.3 0.2 0.2 0.1 0.4 0.3 0.3 13.9 0.6 0.3 0.3 0.1 0.1 10.8 11.2 6.9 9.6 8.5 8.1 8.4 9.2 6.9 6.8 9.4 6.4 6.0 9.6 47.1 53.8 1.6 0.5 18.4 2.3 4.0 1.2 9.2 1.9 39.8 35.8 11.5 1.8 0.0 0.4 0.1 11.9 9.8 8.7 1.5 20.8 1.4 7.4 0.0 2.7 1.1 12.3 0.5 1.3 16.3 5.1 3.8 18.7 42.1 140.5 0.5 0.0 1.8 6.9 4.1 6.9 0.5 0.3 0.3 2.5 0.0 5.6 0.1 8.1 0.0 11.1 2.0 4.8 1.3 2.6 0.5 6.6 0.5 11.1 10.4 1.2 13.1 25.8 1.8 6.2 6.6 0.5 1.0 1.4 1.1 20.5 8.8 11.5 PMEPA1 "STAG1, TMEPAI" ENSG00000124225 "Prostate transmembrane protein, androgen induced 1" Q969W9 20 57648392-57711536 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 110.8" "Cell type enhanced" "Detected in many" "Ductal cells: 339.6;Muller glia cells: 325.9;Pancreatic endocrine cells: 827.5" "Cancer enhanced" "Detected in all" "prostate cancer: 157.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "naive B-cell: 6.3;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 8 "B-cells: 6.3;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "SiHa: 206.1;U-2 OS: 129.9;U-251 MG: 481.8;WM-115: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072291 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA072291: AB_2686509" "unprognostic (2.72e-3)" "prognostic unfavorable (2.45e-4)" "unprognostic (5.77e-2)" "unprognostic (1.73e-1)" "unprognostic (6.61e-2)" "unprognostic (2.11e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.73e-5)" "unprognostic (5.53e-1)" "unprognostic (1.32e-3)" "unprognostic (7.83e-3)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.87e-7)" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (9.87e-3)" "prognostic unfavorable (7.60e-4)" 50.5 14.5 24.2 14.2 75.5 1.3 25.1 38.8 29.9 94.8 1.8 30.7 6.5 48.4 7.1 7.6 19.9 26.0 29.2 24.0 28.3 16.2 3.8 21.8 7.4 32.9 34.1 14.9 31.3 5.0 13.5 3.9 38.8 110.8 8.4 23.6 30.5 20.6 33.2 18.1 12.6 28.8 27.0 6.6 12.2 5.3 36.1 2.4 13.6 13.6 8.9 13.1 29.6 26.2 32.2 75.4 2.3 3.9 2.4 0.0 0.8 4.9 0.2 1.7 0.8 1.5 97.4 0.2 17.7 7.4 51.8 121.1 1.6 100.8 1.3 1.0 4.1 0.0 23.2 0.1 1.5 0.3 0.8 1.2 55.8 4.4 12.1 16.5 13.0 67.8 0.8 1.2 6.2 66.1 3.8 0.7 9.4 15.0 9.6 0.3 36.0 11.3 24.2 0.0 17.7 13.7 206.1 120.3 15.1 5.6 18.8 4.1 33.1 17.9 129.9 1.9 481.8 5.9 0.8 0.5 8.1 1.1 237.1 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.8 0.2 0.1 6.3 1.8 1.2 0.1 0.0 0.1 23.9 0.5 0.6 24.2 75.5 38.8 29.9 24.0 28.3 32.9 34.1 38.8 27.0 36.1 26.2 59.4 57.7 32.3 4.9 32.7 167.0 143.1 120.6 30.7 59.0 38.0 23.0 23.2 125.8 31.7 11.0 2.1 0.2 27.8 57.3 3.9 339.6 1.2 33.4 88.8 55.6 10.1 0.0 19.1 62.5 4.1 40.5 5.1 80.2 59.8 17.5 24.7 0.5 6.1 1.7 32.7 16.9 14.2 3.5 68.0 2.7 3.1 13.4 32.0 31.9 5.8 325.9 0.0 17.6 9.0 827.5 54.2 21.8 25.3 203.1 6.2 2.7 10.1 11.5 72.3 43.8 155.2 0.2 8.8 10.0 178.4 0.1 17.8 9.1 19.3 87.5 POLR3H "C25, KIAA1665, RPC8" ENSG00000100413 "RNA polymerase III subunit H" Q9Y535 22 41525799-41544606 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 163.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046787 Approved Supported Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Centrosome" "HPA046787: AB_2679806" "unprognostic (1.55e-1)" "unprognostic (6.74e-2)" "unprognostic (1.06e-1)" "unprognostic (3.87e-3)" "unprognostic (9.57e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.05e-2)" "unprognostic (1.33e-2)" "unprognostic (5.43e-2)" "prognostic favorable (5.41e-4)" "unprognostic (6.40e-2)" "unprognostic (1.54e-1)" "unprognostic (2.94e-2)" "unprognostic (1.49e-1)" "unprognostic (4.00e-2)" "unprognostic (1.70e-1)" 16.6 21.0 40.4 8.5 38.9 5.4 15.1 38.0 49.5 11.0 33.3 13.4 4.8 14.0 9.0 16.4 15.8 7.9 18.3 39.5 38.6 13.5 26.7 14.2 10.0 41.1 41.7 18.5 12.2 11.9 18.2 6.5 38.1 15.4 5.2 7.0 11.5 10.7 13.8 12.1 9.7 11.7 40.1 10.9 13.4 16.2 41.3 8.0 14.1 9.0 7.7 14.2 9.8 39.4 36.4 23.8 21.4 32.7 23.0 20.9 14.8 30.5 27.3 49.0 39.3 47.9 12.0 30.8 21.9 49.9 27.8 17.8 39.8 48.1 30.6 26.3 50.1 18.4 37.1 23.7 23.9 75.3 30.8 26.3 30.8 64.9 17.4 18.8 23.5 29.3 39.5 19.9 28.0 34.4 19.3 20.1 15.6 49.8 28.1 30.0 16.9 32.6 22.9 21.7 21.2 12.5 37.0 39.7 19.3 13.7 15.6 21.1 22.7 29.8 30.7 49.8 39.8 16.7 28.6 46.6 49.5 26.8 28.9 0.1 12.5 0.2 8.8 18.3 12.6 16.6 8.7 10.4 14.2 13.9 11.6 9.7 0.6 5.4 18.6 13.3 5.8 9.9 40.4 38.9 38.0 49.5 39.5 38.6 41.1 41.7 38.1 40.1 41.3 39.4 6.1 0.0 32.0 15.7 14.8 17.7 12.0 19.0 13.6 18.8 24.9 23.4 6.4 14.3 19.8 16.5 16.7 32.9 7.9 5.0 46.9 30.4 42.6 12.7 15.4 10.3 14.3 19.1 10.0 29.6 30.9 14.8 13.3 8.9 11.4 13.1 9.7 33.3 30.5 21.9 7.1 4.8 14.2 9.5 11.0 163.9 16.8 10.2 24.9 1.9 19.6 24.1 18.6 2.0 6.7 27.6 6.6 20.3 21.8 16.8 4.1 40.7 12.7 20.9 0.0 17.9 16.8 51.6 50.9 21.2 25.6 17.9 10.3 21.2 9.5 11.8 POP7 "RPP2, RPP20" ENSG00000172336 "POP7 homolog, ribonuclease P/MRP subunit" O75817 7 100706121-100707486 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021007 Uncertain Supported Nucleoli,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli, Vesicles" "HPA021007: AB_10963575" "unprognostic (3.19e-1)" "unprognostic (2.45e-2)" "unprognostic (2.72e-2)" "unprognostic (1.80e-3)" "unprognostic (6.47e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (2.98e-2)" "unprognostic (2.28e-1)" "unprognostic (3.12e-2)" "unprognostic (9.50e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.05e-2)" "unprognostic (1.44e-1)" "unprognostic (6.21e-2)" "unprognostic (6.73e-2)" 25.6 31.7 30.1 18.1 31.6 33.9 26.6 33.4 38.6 24.2 23.8 27.9 19.3 27.7 11.0 34.0 21.3 9.8 37.6 32.3 30.8 25.8 67.1 18.2 17.3 30.1 27.8 18.1 31.3 16.6 22.8 16.6 30.8 22.6 9.2 9.6 29.0 13.5 69.0 50.2 22.3 12.1 29.4 22.7 26.4 12.5 29.1 15.6 16.8 31.9 12.0 25.4 24.9 33.9 115.7 115.3 47.2 78.4 25.1 23.9 92.0 65.6 32.4 73.7 73.1 159.8 71.0 97.5 105.1 30.0 81.4 70.4 70.1 79.5 36.8 82.7 212.4 44.9 75.0 166.5 42.1 69.2 49.8 27.6 30.2 76.2 74.8 20.9 41.6 68.9 157.4 77.8 39.8 330.4 158.0 232.9 135.2 77.8 164.4 123.6 50.0 159.4 45.3 65.2 90.4 92.3 54.5 156.2 78.7 42.0 50.0 66.2 41.3 92.0 117.7 191.0 127.6 34.0 99.4 175.8 61.0 115.1 104.6 106.3 63.2 72.4 54.7 64.7 50.7 60.3 54.6 54.3 55.3 47.7 49.5 52.0 39.0 78.9 70.3 51.2 69.8 62.5 30.1 31.6 33.4 38.6 32.3 30.8 30.1 27.8 30.8 29.4 29.1 33.9 30.5 19.2 17.0 2.9 29.7 105.0 32.0 57.2 56.3 26.1 61.6 64.1 27.9 37.1 31.5 35.0 6.2 148.2 25.8 51.8 93.9 75.4 2.1 31.2 32.3 37.2 40.2 50.1 5.2 87.4 181.3 37.3 25.0 35.1 17.7 32.4 33.5 99.0 66.1 32.0 6.0 61.7 67.1 27.3 40.7 7.9 42.0 22.4 56.9 2.8 38.7 41.8 41.2 4.0 5.8 92.2 47.6 37.2 55.1 75.6 69.8 86.1 27.8 21.3 46.0 29.8 52.2 9.2 45.5 74.7 119.2 139.3 27.2 39.9 55.8 43.5 POU2F1 "OCT1, OTF1" ENSG00000143190 "POU class 2 homeobox 1" P14859 1 167220876-167427345 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 270.6;Excitatory neurons: 187.6;Inhibitory neurons: 184.0;Oligodendrocyte precursor cells: 186.0;Oligodendrocytes: 202.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002608, HPA058559, HPA064323" Supported Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" No No "Cluster 34: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "CAB002608: , HPA058559: AB_2683756, HPA064323: AB_2685245" "unprognostic (1.74e-1)" "unprognostic (9.33e-2)" "unprognostic (1.28e-2)" "unprognostic (1.40e-3)" "unprognostic (5.78e-3)" "unprognostic (4.26e-2)" "unprognostic (5.67e-6)" "unprognostic (4.47e-2)" "unprognostic (5.14e-1)" "unprognostic (7.94e-3)" "unprognostic (1.95e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (2.98e-5)" "unprognostic (1.89e-1)" "unprognostic (4.02e-1)" "unprognostic (3.42e-1)" "unprognostic (1.17e-2)" 4.0 2.5 5.0 2.2 5.8 3.9 3.4 7.3 5.2 3.6 2.9 3.7 1.3 4.0 2.6 2.7 3.4 1.4 2.6 4.8 3.8 2.9 2.3 3.5 3.0 4.1 4.2 4.1 2.4 3.4 3.6 2.4 3.9 3.2 2.1 12.9 3.0 2.0 4.1 3.5 3.6 1.4 3.8 4.2 2.6 4.3 5.0 3.8 3.3 2.6 3.4 3.4 3.2 4.4 7.4 4.0 14.8 4.5 1.7 1.7 6.1 0.9 1.6 1.7 1.7 8.1 4.2 8.3 3.8 1.5 1.7 5.6 8.8 2.7 2.6 3.3 3.5 5.9 3.9 7.1 1.1 6.5 3.8 1.2 1.6 2.0 3.6 2.1 2.3 5.7 6.4 4.3 2.3 3.7 6.0 4.3 17.4 4.0 2.3 8.7 5.4 3.7 3.1 4.0 9.0 6.9 5.6 4.1 3.7 7.4 4.6 7.9 3.8 3.4 5.3 2.0 3.5 4.4 2.1 18.3 1.6 3.9 4.4 4.6 0.3 0.3 0.2 0.3 0.3 2.0 0.2 0.0 0.4 0.7 0.3 0.2 0.4 0.2 0.3 0.9 0.2 0.4 5.0 5.8 7.3 5.2 4.8 3.8 4.1 4.2 3.9 3.8 5.0 4.4 19.9 12.8 17.2 270.6 25.2 13.4 11.3 9.7 9.6 58.7 12.5 11.8 15.8 14.3 11.6 20.2 102.2 17.8 20.2 12.3 5.9 10.5 26.2 17.7 18.7 19.8 24.1 14.5 187.6 11.6 18.5 17.5 10.2 18.9 19.7 18.7 15.0 13.3 13.3 47.1 184.0 14.3 8.2 52.5 12.4 44.1 25.7 19.9 7.2 114.3 21.7 43.8 14.4 186.0 202.1 16.5 8.0 20.7 33.5 16.1 5.3 8.3 11.5 101.7 26.3 28.4 16.4 17.6 35.7 12.7 11.1 51.7 14.1 11.0 14.5 21.0 PPA1 "IOPPP, PP, PP1, Ppase, SID6-8061" ENSG00000180817 "Inorganic pyrophosphatase 1" Q15181 10 70202835-70233911 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 1239.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019878, HPA020096" Supported Supported Vesicles NA NA 1000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA019878: AB_1855601, HPA020096: AB_1855600" "unprognostic (1.50e-1)" "unprognostic (2.85e-1)" "unprognostic (4.71e-2)" "unprognostic (2.85e-1)" "unprognostic (1.42e-1)" "unprognostic (4.47e-2)" "unprognostic (2.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.34e-1)" "unprognostic (1.62e-1)" "unprognostic (2.13e-2)" "unprognostic (3.60e-2)" "unprognostic (1.82e-3)" "unprognostic (5.36e-2)" "unprognostic (2.37e-1)" "unprognostic (3.53e-2)" "unprognostic (2.74e-1)" 176.7 198.5 124.3 116.0 138.8 85.0 186.7 166.7 163.0 96.5 123.0 137.3 99.4 85.8 166.7 157.7 110.2 90.3 100.1 125.8 148.5 123.2 150.2 129.0 132.6 153.1 142.3 56.5 188.5 68.5 92.1 103.7 165.4 68.7 152.5 332.0 116.1 78.7 133.0 85.9 125.1 96.8 159.3 64.2 97.5 73.5 141.6 103.5 126.3 137.3 137.3 167.1 140.0 167.0 446.9 181.2 158.8 471.2 421.6 368.8 148.2 163.5 305.3 250.1 261.8 556.7 230.6 641.0 144.5 164.0 162.8 351.2 470.7 318.4 253.8 599.1 443.5 176.1 169.1 321.7 265.8 439.0 106.9 244.2 372.9 201.3 530.7 273.8 307.9 319.2 416.9 336.4 239.4 262.3 426.5 408.7 165.9 614.2 494.8 256.9 181.7 378.2 527.0 276.3 474.4 159.6 179.3 694.5 148.0 110.8 174.3 194.2 141.0 69.0 262.2 229.4 315.2 110.1 259.2 469.8 106.7 605.2 62.0 0.4 68.8 1.7 48.9 55.2 131.1 83.6 112.3 85.6 190.0 59.4 122.7 106.8 4.1 65.8 63.1 44.4 120.4 105.3 124.3 138.8 166.7 163.0 125.8 148.5 153.1 142.3 165.4 159.3 141.6 167.0 207.0 224.4 165.9 17.0 122.7 267.9 366.2 427.3 158.2 184.9 347.8 363.7 93.3 218.8 275.7 108.5 173.0 313.2 63.4 203.3 201.5 540.1 31.7 278.8 196.1 182.1 162.7 88.4 36.8 776.1 298.3 156.9 114.2 512.1 36.8 208.2 38.2 141.8 96.5 85.8 41.2 254.9 160.7 80.1 148.1 31.7 109.6 120.3 181.5 29.0 612.7 1239.0 65.9 21.6 98.4 532.9 213.5 117.4 161.2 512.4 444.5 551.2 92.1 278.4 65.7 97.2 136.8 173.7 170.7 245.8 257.1 245.7 120.9 203.0 347.6 613.9 PPM1N FLJ40125 ENSG00000213889 "Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)" Q8N819 19 45488777-45502510 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 8 "skeletal muscle: 213.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 123.1;Rod photoreceptor cells: 74.3" "Cancer enhanced" "Detected in many" "testis cancer: 11.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "non-classical monocyte: 142.4" "Lineage enriched" "Detected in all" 11 "monocytes: 142.4" "Cell line enhanced" "Detected in many" "OE19: 24.1;RT4: 29.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043577 Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA043577: " "unprognostic (2.38e-2)" "unprognostic (1.11e-2)" "unprognostic (8.53e-2)" "unprognostic (6.59e-2)" "unprognostic (4.71e-1)" "unprognostic (2.64e-2)" "unprognostic (1.98e-3)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "unprognostic (4.45e-2)" "unprognostic (9.27e-2)" "unprognostic (2.48e-2)" "unprognostic (1.11e-16)" "unprognostic (3.42e-2)" "unprognostic (1.79e-1)" "unprognostic (3.92e-2)" "unprognostic (1.86e-3)" 2.0 0.8 15.5 2.0 14.7 2.6 3.3 14.5 19.9 2.0 14.5 2.6 0.6 0.7 1.3 2.6 0.9 1.4 1.3 15.1 15.0 1.4 2.6 2.5 3.0 14.7 14.7 0.6 0.5 2.1 1.1 4.7 15.1 1.2 1.3 25.8 0.9 2.0 213.3 3.1 1.6 1.2 13.7 9.2 2.8 5.3 14.3 2.3 1.1 0.2 3.4 2.4 1.6 16.2 2.6 7.1 1.2 5.1 5.9 7.8 14.7 1.9 3.0 0.6 2.3 1.7 15.8 11.1 3.2 1.8 4.1 7.6 3.0 2.2 0.9 10.9 4.5 9.0 2.7 1.9 1.4 0.8 18.1 3.2 3.6 3.1 1.9 4.0 1.0 4.4 10.3 9.6 1.0 1.9 3.1 4.6 4.0 24.1 1.4 2.0 1.5 3.0 3.4 29.9 5.8 6.8 1.0 11.1 9.2 8.8 3.8 2.7 1.5 8.2 4.7 4.3 1.4 1.7 4.5 2.3 6.1 2.3 7.2 6.7 4.4 3.2 6.4 22.5 5.5 6.3 3.9 6.2 12.8 3.6 4.3 7.9 6.5 3.1 142.4 2.4 4.5 5.7 15.5 14.7 14.5 19.9 15.1 15.0 14.7 14.7 15.1 13.7 14.3 16.2 6.4 0.0 2.7 1.0 7.5 3.4 14.7 6.2 17.6 14.1 5.9 32.5 2.3 17.2 2.5 3.7 31.3 3.2 6.0 5.5 0.0 2.9 12.5 2.0 3.9 3.5 3.0 0.8 1.1 1.8 123.1 6.5 3.1 7.4 7.0 1.0 5.3 1.3 20.1 1.7 1.4 4.2 0.0 15.5 15.7 4.9 0.9 15.2 1.8 1.0 6.1 7.3 20.6 0.0 0.3 3.1 4.7 0.7 1.7 6.7 6.9 0.6 0.8 74.3 0.0 25.6 5.5 2.9 9.1 3.4 4.1 8.5 7.5 0.3 3.1 8.4 PPP5C "PP5, PPP5" ENSG00000011485 "Protein phosphatase 5 catalytic subunit" P53041 19 46347087-46392981 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022641, HPA029065, HPA056933" Approved Supported Vesicles,Cytosol NA NA 120000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 59: Non-specific - Transcription" "Vesicles, Cytosol" "CAB022641: , HPA029065: AB_10610284, HPA056933: AB_2683278" "unprognostic (8.25e-2)" "unprognostic (7.90e-2)" "unprognostic (1.44e-1)" "unprognostic (6.30e-2)" "unprognostic (5.92e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (3.45e-6)" "unprognostic (1.29e-1)" "unprognostic (1.04e-2)" "unprognostic (8.25e-2)" "unprognostic (5.56e-2)" "unprognostic (2.20e-2)" "unprognostic (3.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.35e-1)" "unprognostic (5.92e-3)" "unprognostic (1.37e-1)" 27.4 37.5 27.7 17.7 29.3 14.2 26.3 28.4 36.5 28.0 27.7 31.3 16.8 34.9 9.8 30.4 31.7 13.3 56.4 29.8 28.6 29.1 32.7 28.0 19.7 32.3 28.2 24.7 23.7 32.5 36.6 15.8 33.3 23.7 15.4 14.4 23.0 18.2 58.9 27.5 25.9 20.8 26.2 33.5 33.6 16.9 30.3 20.5 26.2 45.7 15.0 27.7 26.3 28.5 61.9 114.9 66.0 50.1 48.3 50.9 30.6 75.4 59.6 88.2 78.2 82.4 47.9 94.3 39.9 54.0 48.4 49.9 86.2 88.5 24.7 65.9 120.5 76.4 80.9 59.4 54.5 106.6 52.8 47.8 40.9 62.1 45.9 34.2 77.2 79.3 76.0 47.3 49.4 67.5 59.5 203.4 50.2 109.6 61.7 89.0 56.6 76.5 52.8 81.8 93.1 69.7 62.6 78.8 26.9 28.6 49.7 67.8 65.5 38.3 64.3 29.1 79.1 38.0 93.0 111.5 41.7 89.4 65.9 0.0 10.3 3.0 27.8 18.0 17.8 15.1 12.8 22.0 16.8 11.7 12.2 16.8 0.2 22.0 23.4 11.7 14.3 15.4 27.7 29.3 28.4 36.5 29.8 28.6 32.3 28.2 33.3 26.2 30.3 28.5 28.1 6.4 12.5 22.9 16.5 9.4 16.6 20.9 19.9 19.7 13.1 13.5 5.6 44.3 14.2 16.5 16.7 26.4 12.3 25.2 33.2 29.9 1.2 31.3 25.2 19.6 14.9 11.6 18.5 19.5 36.2 17.6 26.0 19.6 4.5 18.6 24.3 24.9 21.6 16.8 23.2 17.0 22.4 12.3 8.2 3.2 17.4 11.9 16.0 11.2 12.1 21.0 17.5 17.6 14.5 26.4 17.0 18.4 25.5 12.1 16.3 21.4 14.6 17.9 39.5 14.6 19.9 26.6 32.0 20.8 13.2 25.7 20.4 23.1 25.0 11.7 PPT1 "CLN1, INCL, PPT" ENSG00000131238 "Palmitoyl-protein thioesterase 1" P50897 1 40072710-40097260 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 251.9;Kupffer cells: 315.8;Langerhans cells: 328.8;Macrophages: 271.3;monocytes: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 1254.3;eosinophil: 624.2;intermediate monocyte: 1006.3;myeloid DC: 1091.1;neutrophil: 683.9;non-classical monocyte: 815.7" "Group enriched" "Detected in all" 4 "dendritic cells: 1091.1;granulocytes: 683.9;monocytes: 1254.3" "Cell line enhanced" "Detected in all" "SK-BR-3: 1082.7;THP-1: 1449.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021546 Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 240000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "HPA021546: AB_1855667" "unprognostic (5.02e-2)" "unprognostic (2.73e-1)" "unprognostic (1.64e-1)" "unprognostic (2.06e-3)" "unprognostic (6.68e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (1.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.16e-2)" "unprognostic (2.39e-1)" "unprognostic (5.20e-3)" "unprognostic (1.75e-1)" "unprognostic (2.30e-1)" "unprognostic (2.93e-2)" "unprognostic (2.08e-2)" 69.8 59.4 92.9 92.7 95.6 117.5 95.7 100.4 135.9 70.1 106.1 50.5 32.1 72.7 60.1 45.1 55.4 57.1 45.3 93.6 101.2 75.8 54.1 128.5 93.9 97.0 96.7 68.6 42.6 79.2 39.0 74.8 99.6 73.4 58.8 89.4 56.8 63.2 21.3 40.3 39.2 95.3 101.6 177.0 45.1 37.6 99.1 78.0 60.0 37.1 75.1 79.1 34.7 113.5 115.6 62.5 93.7 81.0 106.5 92.1 209.8 68.4 127.9 153.0 183.3 350.1 270.5 140.1 118.1 65.2 112.2 209.5 154.9 112.7 163.6 186.4 151.4 100.3 127.2 155.5 137.5 233.7 158.9 103.1 107.5 108.7 126.4 79.7 190.9 108.8 167.7 247.0 80.6 168.1 109.8 88.3 258.3 163.9 93.8 116.0 263.7 226.1 89.2 152.0 114.1 96.9 247.9 1082.7 298.6 111.7 199.3 1449.6 85.2 100.7 147.1 70.7 174.9 161.2 383.8 133.9 109.4 408.7 155.5 85.7 1254.3 624.2 122.2 1006.3 137.9 118.8 171.5 131.3 1091.1 118.6 227.0 168.3 683.9 100.3 815.7 101.8 204.1 1586.9 92.9 95.6 100.4 135.9 93.6 101.2 97.0 96.7 99.6 101.6 99.1 113.5 45.2 28.9 47.7 19.9 33.3 39.6 77.1 30.8 34.7 46.6 55.3 37.5 15.7 41.5 40.0 38.6 16.7 51.7 28.9 4.7 5.9 59.0 64.8 13.8 46.4 49.6 19.9 40.1 28.4 42.1 66.5 56.6 14.8 18.2 84.9 34.6 47.5 9.3 251.9 25.2 39.2 8.1 20.3 315.8 328.8 87.6 31.4 271.3 67.6 31.9 227.2 120.3 28.8 27.6 22.7 22.2 6.0 39.5 34.2 42.4 3.2 18.5 32.3 37.0 19.7 30.5 49.3 17.5 33.0 19.1 27.3 41.2 43.5 39.4 11.4 35.6 PPT2 ENSG00000221988 "Palmitoyl-protein thioesterase 2" Q9UMR5 6 32153441-32163678 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 33.6;Smooth muscle cells: 27.8;Syncytiotrophoblasts: 23.3" "Cancer enhanced" "Detected in all" "melanoma: 21.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 21.3;HEK 293: 27.9;SK-MEL-30: 29.4" HPA000414 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA000414: " "unprognostic (1.90e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.03e-5)" "unprognostic (1.62e-1)" "unprognostic (6.75e-3)" "unprognostic (2.92e-3)" "unprognostic (6.41e-3)" "unprognostic (7.12e-2)" "unprognostic (2.56e-3)" "unprognostic (5.28e-3)" "unprognostic (1.12e-2)" "unprognostic (2.75e-3)" "unprognostic (5.09e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.24e-3)" 19.0 18.0 1.1 2.1 1.1 0.1 18.7 1.1 4.8 26.5 1.0 23.7 1.6 22.0 2.6 28.2 21.7 0.0 24.5 1.1 1.1 22.1 13.9 14.3 1.7 1.1 1.2 46.2 14.3 0.0 13.7 3.9 1.1 17.2 1.5 6.2 14.9 0.0 19.0 29.4 14.9 1.3 1.1 13.3 21.0 8.3 1.1 1.9 14.6 0.2 1.0 18.1 24.2 1.3 0.0 0.0 0.0 0.4 21.3 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.2 1.6 0.7 5.3 2.6 5.0 0.0 0.0 27.9 4.0 0.0 0.0 0.0 3.5 1.8 4.0 1.6 0.0 7.3 3.8 0.0 14.9 0.0 1.8 1.7 13.0 4.6 0.0 0.0 0.9 0.0 6.3 5.8 0.0 14.3 0.0 1.6 5.4 8.7 5.2 29.4 15.2 0.0 3.7 0.8 0.0 11.4 0.0 0.0 0.8 12.6 3.0 5.8 2.2 3.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.7 0.0 0.1 1.1 1.1 1.1 4.8 1.1 1.1 1.1 1.2 1.1 1.1 1.1 1.3 9.4 0.0 0.5 0.0 0.7 3.3 2.9 2.6 5.7 12.4 4.2 2.9 6.8 2.8 2.8 3.7 16.7 14.5 4.4 2.4 1.9 1.8 0.3 4.5 4.3 7.6 4.9 17.4 0.0 3.0 9.2 6.3 1.5 5.0 0.0 33.6 6.4 4.4 3.0 3.3 0.0 2.6 2.0 1.3 1.3 1.1 4.1 1.1 7.2 0.0 0.2 9.5 3.1 0.0 0.0 1.8 3.8 3.0 1.7 1.4 1.4 3.1 0.6 6.1 0.0 3.6 27.8 4.0 6.7 4.4 2.3 23.3 1.4 5.0 3.0 1.5 PRCP "HUMPCP, PCP" ENSG00000137509 Prolylcarboxypeptidase P42785 11 82822936-82970584 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 348.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 463.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017065, HPA071115" Approved Supported Vesicles "Intracellular and membrane" NA NA 42000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA017065: AB_1855676, HPA071115: " "unprognostic (3.24e-1)" "unprognostic (2.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (2.54e-1)" "unprognostic (1.33e-2)" "unprognostic (9.22e-2)" "unprognostic (1.42e-1)" "unprognostic (7.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.70e-1)" "unprognostic (1.88e-2)" "prognostic favorable (2.65e-6)" "unprognostic (7.16e-2)" "unprognostic (1.73e-2)" "unprognostic (3.49e-1)" "unprognostic (4.07e-1)" 74.8 87.3 81.1 57.8 82.1 37.7 70.0 84.3 109.1 91.9 95.0 49.3 28.6 62.9 81.4 62.1 57.0 64.3 70.0 76.6 85.6 144.7 151.9 58.1 92.1 84.4 82.1 53.5 37.9 78.4 34.5 152.8 80.9 52.5 46.6 21.9 85.6 55.5 15.9 54.1 31.8 80.8 89.0 54.0 32.0 41.8 86.0 33.7 63.7 28.5 85.0 100.2 57.5 86.7 34.9 41.8 49.6 121.0 463.5 146.7 67.1 67.5 131.9 70.9 97.0 103.5 70.7 55.9 100.7 117.9 72.6 53.2 53.7 45.2 72.0 43.9 38.3 37.7 56.5 76.7 86.2 31.0 124.7 122.0 39.3 72.7 68.6 166.5 224.0 26.3 39.1 69.8 72.7 19.5 4.9 171.7 33.9 90.3 31.1 27.1 97.0 65.1 118.0 71.2 24.0 51.9 101.9 60.2 41.5 80.6 66.6 49.6 65.0 78.8 77.4 71.1 33.5 64.2 113.6 46.3 32.9 41.7 44.5 53.5 76.9 50.9 13.7 79.0 16.1 31.7 14.0 15.9 140.2 34.2 12.0 17.4 89.0 34.7 64.8 27.9 14.8 49.6 81.1 82.1 84.3 109.1 76.6 85.6 84.4 82.1 80.9 89.0 86.0 86.7 86.9 19.2 12.9 58.8 45.5 31.4 41.5 53.4 25.0 11.7 26.2 25.1 26.6 37.1 25.2 62.5 2.1 65.1 29.0 9.8 29.4 32.9 44.9 17.4 37.7 180.4 19.7 13.7 42.2 12.0 120.1 73.6 23.9 29.9 12.7 18.2 348.7 65.4 80.7 16.8 38.5 19.1 14.2 152.9 118.9 47.6 44.1 88.0 71.2 33.7 79.5 53.5 28.8 34.7 10.5 8.2 10.2 46.3 62.2 23.3 3.9 83.8 9.1 5.3 65.7 25.5 25.6 60.8 6.3 54.3 34.9 52.9 22.3 27.7 20.9 39.2 PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851325 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2792.8;Kupffer cells: 2427.0;Macrophages: 1916.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11615.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 5104.0;hTERT-RPE1: 6978.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB004647: AB_425625, HPA004426: AB_1079701" "unprognostic (4.43e-3)" "unprognostic (2.69e-1)" "unprognostic (1.64e-2)" "unprognostic (8.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-3)" "unprognostic (2.79e-1)" "unprognostic (3.31e-2)" "unprognostic (3.25e-2)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.06e-1)" 1068.6 1192.2 831.4 874.2 946.7 834.2 683.8 873.7 831.7 1073.9 1023.0 667.1 475.6 879.3 951.2 605.5 724.7 1115.6 1413.3 830.5 1081.8 860.4 906.4 1118.6 956.1 957.6 894.0 1106.9 544.7 1167.5 563.5 869.3 885.3 773.9 625.5 665.2 580.9 936.8 1409.5 544.4 487.7 1138.6 1025.9 1045.9 664.0 489.1 1048.8 672.3 875.9 987.5 560.4 941.2 578.3 1325.1 455.9 847.4 540.4 1121.0 5104.0 2910.1 1900.2 799.9 2368.3 620.8 735.9 795.4 1131.9 245.6 1608.1 1321.6 1038.9 964.1 207.5 659.1 434.8 481.4 381.8 288.9 352.3 459.6 1970.7 188.8 1596.0 1871.8 1479.1 625.7 1177.6 6978.9 1128.1 345.8 420.5 1158.1 777.0 294.9 843.8 290.1 249.5 575.4 404.0 172.9 301.3 696.7 730.3 764.4 584.4 515.8 751.1 2248.3 3122.2 700.4 454.4 431.1 1467.0 861.8 610.0 587.1 670.5 1289.0 1038.7 435.4 1375.5 374.4 650.0 863.2 10095.9 1127.5 424.2 11615.6 349.8 466.7 342.9 368.8 3481.1 425.5 370.1 350.6 2890.4 365.8 10148.2 1758.2 422.8 15009.0 831.4 946.7 873.7 831.7 830.5 1081.8 957.6 894.0 885.3 1025.9 1048.8 1325.1 263.2 253.2 339.0 136.8 173.9 228.3 253.4 487.0 108.1 193.8 254.6 158.7 664.1 253.1 318.9 476.3 127.2 891.6 260.2 434.8 70.5 1043.6 19.3 147.0 246.6 311.4 261.9 160.5 86.1 456.1 872.6 623.8 187.6 195.2 398.1 210.8 426.9 509.2 2792.8 333.1 93.7 242.2 343.8 2427.0 779.7 54.1 458.6 1916.9 663.5 105.9 1528.9 495.6 182.3 92.5 117.6 357.7 298.3 551.8 503.0 244.8 370.6 311.6 297.2 164.3 276.1 273.6 263.8 55.2 126.3 137.2 198.0 1073.2 138.9 624.1 228.3 223.9 PSMA4 "HC9, HsT17706" ENSG00000041357 "Proteasome 20S subunit alpha 4" P25789 15 78540405-78552417 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004973, HPA055466, HPA060613" Supported Supported Nucleoplasm,Vesicles,Cytosol No No 13000000 "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 32: U-937 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" Vesicles "CAB004973: AB_425627, HPA055466: AB_2682824, HPA060613: AB_2684332" "unprognostic (1.80e-1)" "unprognostic (7.08e-3)" "unprognostic (1.31e-1)" "unprognostic (1.62e-1)" "unprognostic (4.71e-2)" "unprognostic (5.35e-2)" "unprognostic (6.26e-3)" "unprognostic (1.09e-1)" "unprognostic (3.28e-2)" "unprognostic (2.08e-3)" "unprognostic (2.75e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (6.74e-10)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (3.78e-3)" "unprognostic (6.32e-3)" 92.9 105.0 62.5 106.3 64.4 107.6 87.5 66.2 98.8 78.9 65.6 105.1 108.9 89.6 74.5 118.2 71.6 66.0 108.4 64.7 69.1 98.1 152.1 87.9 136.9 67.6 65.5 64.6 67.3 73.4 54.4 85.8 67.5 97.2 109.6 50.3 70.3 64.2 180.6 78.3 101.3 99.3 69.3 115.3 88.5 109.9 65.6 156.5 70.6 121.6 128.7 118.8 81.2 69.9 274.2 386.9 327.7 290.8 202.1 189.5 256.3 250.2 199.9 301.4 320.6 404.9 386.9 590.8 359.7 232.5 337.4 363.9 669.1 271.8 289.1 244.2 465.7 497.6 271.6 330.1 326.9 512.6 294.5 154.6 166.8 255.0 250.9 185.4 330.7 319.1 544.2 225.0 249.6 392.3 347.5 477.4 309.7 315.3 224.5 297.7 432.9 198.9 309.5 469.4 287.6 209.9 401.3 289.5 327.5 402.2 267.8 414.7 265.8 223.7 298.6 249.3 434.2 204.0 517.9 556.2 209.9 756.7 252.6 126.0 251.9 172.9 136.2 403.9 140.3 156.0 142.0 144.7 327.4 119.9 111.7 137.0 112.8 209.4 394.8 185.4 216.8 405.6 62.5 64.4 66.2 98.8 64.7 69.1 67.6 65.5 67.5 69.3 65.6 69.9 119.0 128.2 118.5 17.3 124.1 231.6 269.6 765.7 84.2 57.8 88.5 95.8 163.7 105.8 327.0 121.4 10.4 478.9 128.4 145.3 311.0 296.2 689.4 158.0 183.6 162.5 146.2 153.2 18.0 292.7 450.6 159.9 78.0 126.0 174.2 152.9 114.9 178.9 320.4 72.3 19.6 216.2 506.6 143.2 201.7 399.0 151.0 176.9 133.4 23.4 308.6 63.5 149.3 11.1 21.5 256.0 165.7 147.4 108.0 249.3 195.8 367.2 280.0 39.8 151.2 95.4 241.1 417.1 181.0 106.4 212.8 447.1 128.6 166.7 234.7 258.4 PSME3IP1 "C16orf94, FAM192A, NIP30, PIP30" ENSG00000172775 "Proteasome activator subunit 3 interacting protein 1" Q9GZU8 16 57152466-57186116 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 82.3;Cytotrophoblasts: 56.7;Extravillous trophoblasts: 59.5;Hofbauer cells: 64.6;Syncytiotrophoblasts: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054382, HPA059652" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "HPA054382: AB_2682469, HPA059652: AB_2684095" "unprognostic (1.69e-2)" "unprognostic (5.20e-2)" "unprognostic (1.36e-1)" "unprognostic (9.20e-3)" "unprognostic (4.69e-3)" "unprognostic (2.45e-2)" "unprognostic (1.01e-2)" "unprognostic (2.22e-1)" "unprognostic (6.09e-2)" "unprognostic (1.52e-2)" "unprognostic (1.41e-1)" "unprognostic (4.19e-1)" "unprognostic (3.00e-1)" "unprognostic (3.87e-3)" "unprognostic (4.14e-2)" "unprognostic (1.58e-1)" "unprognostic (2.56e-3)" 48.8 50.2 80.5 72.9 93.9 151.0 66.7 85.8 99.0 52.4 83.8 75.4 67.6 54.1 64.7 63.5 54.1 47.3 59.2 78.4 89.7 66.3 62.6 57.6 94.8 91.7 87.3 54.6 55.3 76.7 65.3 56.0 87.3 64.7 87.5 75.2 55.2 50.3 79.0 90.3 76.1 52.3 87.9 93.3 62.6 96.8 85.8 85.0 71.5 66.0 96.5 53.3 56.1 103.7 119.3 148.6 163.6 109.8 70.3 86.2 153.4 138.3 102.3 166.3 107.1 141.3 122.5 179.2 150.6 105.8 84.2 155.9 114.4 137.9 167.1 80.3 92.1 125.0 141.6 148.3 101.0 154.8 170.8 86.6 134.8 158.2 127.4 101.8 121.0 134.4 170.1 56.5 110.8 88.2 169.4 143.2 105.1 88.0 111.3 205.6 236.9 174.5 113.1 96.4 116.3 133.9 250.2 105.2 92.7 113.0 87.1 105.9 120.2 122.0 102.3 90.2 103.7 133.2 113.1 228.6 125.0 109.7 119.6 170.3 78.3 124.1 47.6 93.0 46.8 83.1 45.8 44.7 90.0 77.8 47.0 49.1 107.6 57.1 123.4 62.4 69.2 68.1 80.5 93.9 85.8 99.0 78.4 89.7 91.7 87.3 87.3 87.9 85.8 103.7 16.9 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 82.3 0.0 0.0 0.0 0.0 56.7 10.2 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 59.5 16.8 0.0 0.0 0.0 0.0 0.0 0.0 64.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 53.1 1.5 0.0 0.0 0.0 PTGS1 "COX1, PGHS-1, PTGHS" ENSG00000095303 "Prostaglandin-endoperoxide synthase 1" P23219 9 122370530-122395703 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 108.3;skin 1: 152.5;urinary bladder: 175.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 109.9;Glandular and luminal cells: 191.9;granulocytes: 208.0;Hepatic stellate cells: 61.8;Macrophages: 55.3;Suprabasal keratinocytes: 58.7" "Cancer enhanced" "Detected in all" "ovarian cancer: 53.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 28.9" "Group enriched" "Detected in many" 6 "dendritic cells: 20.0;granulocytes: 28.9;monocytes: 13.1" "Cell line enhanced" "Detected in many" "ASC diff: 113.7;ASC TERT1: 89.5;BJ: 115.2;BJ hTERT+: 156.0;HEL: 73.6;HMC-1: 298.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002834, CAB020315" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Vesicles "CAB020315: , HPA002834: AB_1079711" "unprognostic (4.20e-1)" "unprognostic (6.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.27e-2)" "unprognostic (5.88e-2)" "unprognostic (2.00e-2)" "unprognostic (1.22e-3)" "unprognostic (3.32e-1)" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (4.03e-2)" "unprognostic (1.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (9.35e-4)" 12.8 2.9 3.1 10.5 3.2 9.0 6.7 4.2 4.8 5.8 5.5 108.3 10.8 6.1 2.2 67.3 43.2 9.6 12.6 7.4 5.5 9.3 3.0 11.3 4.6 6.5 5.2 2.0 1.8 2.0 4.8 2.2 6.3 21.1 24.2 0.7 4.3 6.1 2.1 152.5 17.7 16.1 6.7 8.0 20.5 0.9 7.0 2.2 3.2 4.0 11.6 175.0 15.9 11.9 0.3 0.5 0.4 0.0 113.7 89.5 0.0 115.2 156.0 1.0 1.1 0.0 0.2 4.2 5.4 19.7 0.3 7.1 0.4 10.5 0.9 0.0 0.2 73.6 0.6 0.0 32.9 5.2 298.4 46.1 1.2 5.7 0.3 0.0 42.3 0.1 0.1 0.3 2.3 0.0 0.2 6.6 1.6 0.0 0.5 0.3 1.4 8.6 14.7 0.0 0.5 0.6 0.6 9.5 0.2 0.5 0.3 8.4 1.0 0.7 0.6 1.7 0.1 0.3 0.2 0.0 0.4 31.6 0.3 28.9 12.1 23.3 0.0 13.1 0.0 2.4 0.0 0.0 20.0 3.5 0.1 0.0 5.2 2.8 10.2 1.4 0.2 21.9 3.1 3.2 4.2 4.8 7.4 5.5 6.5 5.2 6.3 6.7 7.0 11.9 0.9 0.0 6.6 0.0 5.9 9.9 2.6 7.7 0.0 0.1 1.1 1.4 1.6 4.3 2.2 42.3 0.0 0.1 0.2 0.1 0.0 0.6 0.1 109.9 10.4 24.7 1.8 18.7 0.8 0.5 0.3 10.7 2.0 191.9 208.0 0.1 61.8 0.8 26.1 0.0 0.5 0.6 4.1 15.5 20.7 0.3 1.5 55.3 3.6 16.9 11.7 0.0 7.2 1.0 0.1 0.6 0.6 0.0 0.3 2.8 0.0 0.0 0.8 0.1 0.0 1.4 3.6 0.0 0.2 18.2 58.7 0.4 3.4 0.1 1.0 0.8 PTPN23 "DKFZP564F0923, HD-PTP, KIAA1471" ENSG00000076201 "Protein tyrosine phosphatase non-receptor type 23" Q9H3S7 3 47381011-47413435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016845 Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear bodies" Vesicles "HPA016845: AB_1855926" "unprognostic (1.17e-3)" "unprognostic (8.68e-2)" "unprognostic (2.56e-1)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (6.24e-2)" "unprognostic (1.07e-3)" "unprognostic (2.07e-2)" "unprognostic (9.55e-2)" "unprognostic (7.12e-2)" "unprognostic (5.67e-2)" "unprognostic (4.34e-2)" "prognostic favorable (1.82e-4)" "unprognostic (3.05e-2)" "unprognostic (4.40e-1)" "unprognostic (9.53e-2)" "unprognostic (4.68e-2)" 18.5 19.1 6.2 12.6 9.2 14.7 17.4 5.8 10.5 23.3 5.1 16.3 14.3 20.9 7.5 19.0 19.2 8.4 13.2 7.1 7.2 17.5 14.0 18.7 9.1 8.8 7.2 23.5 20.2 23.5 30.9 11.6 8.5 18.7 6.5 8.5 20.0 11.4 30.0 26.4 18.4 8.8 5.5 20.0 16.1 15.6 7.7 8.0 27.1 8.9 7.3 18.5 20.4 14.4 21.5 29.9 16.4 21.4 21.0 16.0 15.8 19.2 18.9 17.5 14.8 25.0 20.7 15.1 17.2 21.9 31.2 19.0 14.3 20.8 8.5 14.3 15.1 21.0 22.2 24.0 23.0 12.3 27.5 21.4 20.9 22.9 23.2 12.4 21.7 12.5 15.9 20.3 19.0 30.2 11.5 10.4 17.5 14.9 20.1 7.2 7.9 18.5 13.2 40.9 8.6 20.6 17.1 35.6 13.6 9.8 20.3 12.0 22.4 26.7 22.2 37.7 27.5 28.8 20.4 8.7 29.0 11.6 19.5 0.8 0.2 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.2 0.0 0.2 0.3 0.3 6.2 9.2 5.8 10.5 7.1 7.2 8.8 7.2 8.5 5.5 7.7 14.4 11.1 9.6 7.0 17.0 8.2 8.0 5.2 6.9 13.6 11.7 9.5 8.0 8.7 8.6 9.5 5.5 14.6 10.6 11.0 15.7 1.9 10.5 2.1 10.3 13.7 12.4 7.3 2.5 9.8 8.9 7.9 9.1 26.5 21.1 2.5 14.9 11.4 12.7 13.9 16.8 12.0 16.3 20.3 10.4 5.5 3.1 19.3 9.5 12.4 7.5 8.7 8.8 6.2 9.5 14.3 13.5 10.4 13.5 15.4 9.3 14.6 9.4 12.6 14.2 6.6 10.2 8.8 13.6 13.3 13.2 10.9 9.3 8.9 9.4 12.8 8.2 RAB11FIP2 "KIAA0941, nRip11, Rab11-FIP2" ENSG00000107560 "RAB11 family interacting protein 2" Q7L804 10 118004916-118046941 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 82.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037726 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoplasm "HPA037726: AB_10672390" "unprognostic (1.97e-1)" "unprognostic (1.68e-2)" "unprognostic (3.61e-1)" "unprognostic (4.45e-2)" "unprognostic (1.30e-1)" "unprognostic (5.58e-2)" "unprognostic (2.17e-2)" "unprognostic (3.34e-2)" "unprognostic (1.83e-2)" "unprognostic (2.15e-1)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "prognostic favorable (9.69e-5)" "unprognostic (1.17e-1)" "unprognostic (1.56e-1)" "unprognostic (1.90e-1)" "unprognostic (2.17e-1)" 8.6 6.6 5.2 6.6 7.0 13.8 6.9 4.8 8.5 10.2 2.4 8.2 3.6 18.8 28.5 6.3 11.8 8.3 6.1 7.1 3.4 12.2 5.4 7.6 6.9 2.8 4.6 9.9 5.6 6.3 4.3 8.2 2.2 10.8 4.9 10.3 4.8 24.7 5.0 5.9 5.5 19.5 3.7 6.6 17.2 7.8 5.3 6.2 11.4 7.5 5.5 7.6 6.2 6.1 7.1 8.8 7.3 9.3 11.9 15.0 7.8 13.8 15.8 8.3 8.6 7.4 7.4 14.5 10.8 14.0 6.1 4.8 10.1 6.1 12.8 3.8 10.9 5.1 9.1 5.1 17.2 9.7 5.5 14.8 11.3 11.6 25.4 11.0 5.1 9.3 3.9 12.1 10.9 2.5 7.5 7.3 6.2 3.1 6.2 6.4 26.0 4.9 12.4 5.6 1.7 13.5 9.8 3.9 17.3 8.7 3.0 8.9 7.7 11.2 8.9 13.3 13.8 8.9 7.8 9.4 11.5 16.4 7.0 0.2 0.2 0.2 0.2 0.1 0.2 0.3 0.2 0.2 0.1 0.4 0.4 0.2 0.3 0.1 0.1 0.5 0.1 0.0 5.2 7.0 4.8 8.5 7.1 3.4 2.8 4.6 2.2 3.7 5.3 6.1 16.7 57.7 31.5 79.7 17.7 10.3 8.8 4.4 12.5 28.1 10.1 10.7 25.8 24.3 6.0 42.3 29.2 11.6 15.1 5.5 7.9 12.6 16.5 13.1 31.0 14.1 14.5 17.4 63.8 18.7 7.9 29.1 14.8 15.7 3.8 28.0 11.4 8.6 11.4 38.7 57.9 6.6 4.1 23.0 12.2 6.6 33.5 16.2 23.2 34.7 19.4 26.0 15.5 53.8 82.9 16.6 4.7 28.6 17.0 11.1 5.4 18.1 7.3 31.4 26.3 34.0 25.8 14.9 21.2 9.2 9.5 5.2 12.9 19.2 6.5 6.4 RAB14 "FBP, RAB-14" ENSG00000119396 "RAB14, member RAS oncogene family" P61106 9 121178133-121223014 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026419, CAB037066" Approved Supported Vesicles NA NA 2700000 "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB037066: AB_1841128, HPA026419: AB_1855996" "unprognostic (1.30e-3)" "unprognostic (3.12e-2)" "unprognostic (9.01e-2)" "unprognostic (7.18e-2)" "unprognostic (6.53e-2)" "unprognostic (3.00e-1)" "unprognostic (1.39e-1)" "unprognostic (1.18e-1)" "unprognostic (2.52e-1)" "unprognostic (6.90e-2)" "unprognostic (3.05e-2)" "unprognostic (9.71e-3)" "prognostic favorable (1.79e-8)" "unprognostic (1.38e-1)" "unprognostic (3.17e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" 39.0 38.7 37.5 35.6 39.7 66.5 42.1 40.3 47.7 37.8 32.6 42.8 39.9 35.6 34.2 63.2 34.0 30.7 32.4 38.4 40.9 50.0 82.8 49.2 41.1 39.6 39.9 35.9 27.6 45.8 28.9 43.1 40.5 38.8 42.4 45.5 34.6 38.1 39.4 56.4 38.9 33.4 40.8 38.3 44.3 33.8 40.2 35.2 43.8 38.9 49.5 43.9 40.8 46.8 53.8 53.7 66.9 56.3 76.2 82.5 52.6 74.8 59.6 56.6 44.7 42.6 57.0 51.2 42.5 72.0 49.2 100.1 48.1 55.8 63.6 44.4 31.7 55.7 69.0 43.9 52.6 60.1 63.8 53.0 98.5 58.2 63.4 62.5 81.2 47.1 42.8 45.6 85.6 50.8 58.5 48.1 39.7 104.8 59.9 45.8 72.3 60.4 62.3 76.0 58.9 34.4 89.0 78.0 53.8 47.1 82.1 46.8 76.0 60.1 43.9 75.3 53.0 40.8 82.6 52.3 56.6 51.9 80.7 34.4 29.4 33.5 22.4 41.5 22.4 24.6 20.9 24.7 31.4 23.4 24.6 25.0 31.8 26.5 43.7 19.0 29.3 24.0 37.5 39.7 40.3 47.7 38.4 40.9 39.6 39.9 40.5 40.8 40.2 46.8 102.6 160.3 103.9 23.5 64.4 157.9 78.2 84.8 97.3 93.8 70.7 58.8 39.2 62.9 96.2 62.5 37.5 85.2 79.6 95.1 86.1 81.3 41.9 80.7 89.8 84.5 60.3 44.4 42.5 64.4 83.0 68.7 64.7 94.4 77.2 58.1 61.1 113.6 91.0 94.2 38.0 59.8 95.6 89.9 105.4 36.2 51.9 80.7 110.3 44.0 84.8 100.5 49.4 38.2 59.0 80.7 52.9 56.4 50.2 81.0 63.2 103.3 86.8 62.0 59.2 64.0 105.6 112.9 113.6 120.0 202.4 116.2 74.3 82.5 64.0 106.0 RAB20 FLJ20429 ENSG00000139832 "RAB20, member RAS oncogene family" Q9NX57 13 110523066-110561722 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 91.3;Hofbauer cells: 105.0;Kupffer cells: 92.1;Macrophages: 100.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 60.9;SK-BR-3: 85.7;T-47d: 54.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA002882, HPA052111, HPA068647" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "HPA002882: , HPA052111: AB_2681732, HPA068647: AB_2686013" "unprognostic (5.59e-3)" "unprognostic (1.30e-1)" "unprognostic (3.48e-1)" "unprognostic (1.42e-3)" "unprognostic (1.30e-1)" "unprognostic (3.82e-2)" "unprognostic (1.14e-2)" "unprognostic (5.99e-2)" "unprognostic (9.43e-2)" "unprognostic (2.06e-2)" "unprognostic (9.41e-2)" "unprognostic (2.65e-1)" "prognostic favorable (8.57e-4)" "unprognostic (6.96e-2)" "unprognostic (4.32e-2)" "unprognostic (2.28e-2)" "prognostic favorable (4.48e-4)" 31.1 55.4 5.7 21.7 5.5 25.3 23.4 5.6 7.9 11.7 9.6 20.7 27.6 6.9 4.8 4.6 11.5 18.0 21.4 5.2 7.0 26.1 51.4 30.7 16.4 7.0 6.0 20.5 24.2 6.2 9.7 22.8 6.8 12.1 14.3 2.6 10.7 5.0 5.8 4.6 25.3 7.6 6.6 44.5 28.6 10.6 7.4 3.9 22.0 2.3 5.1 20.6 6.7 8.4 20.1 2.9 1.9 3.8 12.4 3.3 31.3 1.7 6.2 8.1 12.5 47.9 39.9 0.0 13.9 1.7 10.8 7.5 3.8 12.3 4.2 22.5 3.0 19.8 3.6 22.6 7.8 2.8 5.7 6.9 2.0 4.2 1.2 6.3 3.1 3.3 3.8 0.0 1.8 24.0 0.1 29.0 4.0 60.9 8.5 1.9 0.1 9.0 14.2 26.3 0.5 2.1 3.8 85.7 27.4 6.2 54.4 30.5 2.3 2.0 4.2 0.2 2.7 0.1 0.0 0.2 27.7 38.9 4.2 7.8 35.5 7.1 1.0 33.3 1.3 3.5 2.8 0.9 15.8 2.8 6.5 2.3 26.3 0.0 26.6 0.8 0.9 11.2 5.7 5.5 5.6 7.9 5.2 7.0 7.0 6.0 6.8 6.6 7.4 8.4 18.6 19.2 20.4 4.2 10.6 4.5 10.9 14.1 10.8 0.2 12.8 13.0 5.0 48.6 16.2 25.8 0.0 34.6 1.8 31.1 31.3 60.3 1.6 20.7 2.6 10.3 18.0 0.0 0.4 67.9 91.3 11.5 15.3 23.2 21.0 41.1 53.6 34.5 105.0 0.0 0.4 23.9 28.5 92.1 19.9 1.6 3.7 100.5 7.2 8.4 16.2 7.4 0.0 4.5 0.1 36.4 17.2 6.4 0.4 8.0 48.1 68.9 20.4 2.0 13.1 6.2 26.2 1.0 13.2 1.9 3.0 20.0 3.6 7.2 24.0 11.1 RAB29 "RAB7L, RAB7L1" ENSG00000117280 "RAB29, member RAS oncogene family" O14966 1 205767986-205775482 "Predicted intracellular proteins" "Differentiation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 73.1" "Cell type enhanced" "Detected in many" "dendritic cells: 82.3;monocytes: 76.4;NK-cells: 129.8;Proximal tubular cells: 187.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020822, HPA026303" Approved Supported Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB020822: , HPA026303: AB_1856016" "unprognostic (5.38e-2)" "unprognostic (1.76e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.82e-5)" "unprognostic (9.50e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.60e-2)" "unprognostic (3.14e-1)" "unprognostic (5.50e-2)" "unprognostic (2.45e-1)" "unprognostic (3.05e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.53e-1)" "unprognostic (8.20e-3)" "unprognostic (1.42e-1)" 13.5 14.4 12.5 20.4 14.1 7.1 14.1 14.3 12.1 8.7 10.5 12.6 10.6 8.3 23.8 7.8 6.2 16.9 13.1 12.3 14.3 73.1 19.4 13.5 35.1 15.9 12.9 7.9 9.2 25.5 5.9 7.2 15.8 13.8 10.1 6.8 19.8 13.9 6.4 5.5 12.4 14.8 14.3 24.3 10.4 4.6 15.3 12.1 33.4 6.0 28.0 15.7 5.7 17.0 20.4 18.6 2.8 13.1 52.5 29.8 9.7 14.1 43.2 28.9 34.4 5.6 28.7 21.6 13.6 24.3 34.6 11.2 32.8 37.3 26.4 88.3 15.3 16.4 7.3 9.5 25.4 16.1 23.2 29.0 24.6 23.3 32.8 24.0 37.2 19.8 16.2 24.2 41.2 7.6 17.7 8.3 13.1 25.4 14.0 3.7 43.1 17.5 33.6 27.7 4.4 12.5 10.0 45.0 37.8 10.3 22.0 13.2 38.7 29.7 15.0 43.5 20.6 39.4 87.0 11.5 30.1 26.3 22.5 92.4 22.6 62.3 92.2 43.8 86.9 50.8 51.0 79.5 33.4 45.8 37.2 63.5 8.8 94.1 53.9 10.4 53.3 51.3 12.5 14.1 14.3 12.1 12.3 14.3 15.9 12.9 15.8 14.3 15.3 17.0 16.3 19.2 17.7 11.1 61.2 0.0 6.3 0.0 13.6 2.1 19.5 16.0 19.3 21.5 6.2 31.3 0.0 12.0 82.3 1.9 29.4 18.7 5.1 2.0 6.3 18.6 4.9 10.8 7.8 10.1 6.4 11.2 10.7 3.5 13.3 9.2 14.6 33.7 32.8 0.0 10.2 3.7 0.0 30.1 0.0 4.1 14.3 34.0 0.0 10.3 76.4 26.5 129.8 10.6 9.8 8.3 4.8 20.7 34.8 10.7 9.5 187.7 2.9 2.0 6.6 10.0 6.7 3.8 11.8 9.3 0.0 2.9 51.7 19.7 5.5 6.9 RAB5B ENSG00000111540 "RAB5B, member RAS oncogene family" P61020 12 55973913-55996683 "Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010224, HPA068337" Approved Supported Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "CAB010224: AB_2175453, HPA068337: AB_2685974" "prognostic unfavorable (2.24e-5)" "unprognostic (1.86e-1)" "unprognostic (1.91e-1)" "unprognostic (7.66e-3)" "unprognostic (2.09e-1)" "unprognostic (8.42e-2)" "unprognostic (9.16e-3)" "unprognostic (3.09e-1)" "unprognostic (3.13e-1)" "unprognostic (8.31e-3)" "unprognostic (8.64e-2)" "unprognostic (2.26e-1)" "unprognostic (2.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.74e-1)" "unprognostic (2.85e-1)" "unprognostic (2.49e-1)" 50.9 54.4 95.4 39.4 102.3 35.0 68.2 106.2 96.8 76.8 76.5 72.2 52.4 73.8 92.4 99.8 75.7 55.8 87.2 93.1 99.5 70.1 68.8 72.9 44.5 103.5 105.6 85.4 47.9 112.1 31.4 63.4 106.0 74.6 80.6 72.9 61.7 94.6 100.6 92.4 50.4 79.9 103.6 48.1 67.0 57.1 99.9 64.0 64.6 127.6 76.0 65.6 69.6 112.9 62.3 39.1 80.2 59.4 128.5 115.9 72.1 56.1 102.3 68.3 57.5 67.5 76.7 34.7 65.5 107.6 50.3 44.8 51.4 77.8 63.3 44.1 39.5 39.3 53.1 38.6 94.5 33.2 61.6 94.9 142.7 64.2 54.2 153.0 87.0 42.2 36.2 99.3 87.3 42.3 42.6 51.9 35.8 51.5 35.2 36.5 49.9 45.1 128.2 100.7 40.0 35.6 73.1 72.4 89.0 88.3 104.6 102.5 72.3 44.5 32.5 32.8 22.2 56.4 46.9 21.8 71.5 30.7 38.4 18.5 10.1 32.6 11.1 9.3 10.3 8.9 9.0 9.9 8.0 6.9 10.2 8.0 27.4 7.6 10.6 8.0 7.6 8.9 95.4 102.3 106.2 96.8 93.1 99.5 103.5 105.6 106.0 103.6 99.9 112.9 24.4 57.7 37.1 13.1 26.7 51.7 26.5 34.0 35.3 33.3 54.4 38.2 53.2 55.8 34.0 42.3 52.1 44.0 29.1 88.1 35.2 49.4 11.1 24.1 22.8 30.8 38.9 29.8 21.4 37.1 42.8 33.1 37.2 33.9 19.7 34.1 42.1 86.0 31.1 16.8 23.4 51.1 16.2 46.4 52.3 27.7 53.4 25.4 35.6 11.2 64.7 41.6 32.0 11.1 26.3 71.3 44.4 59.5 27.1 57.0 44.7 35.9 23.9 31.6 59.2 31.9 33.2 36.8 25.6 64.7 89.2 88.0 25.0 23.4 42.7 65.8 RABEP1 "neurocrescin, RAB5EP, rabaptin-5, RABPT5" ENSG00000029725 "Rabaptin, RAB GTPase binding effector protein 1" Q15276 17 5282265-5386340 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004549, HPA019669, HPA024235, HPA024691" Supported Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB004549: AB_628192, HPA019669: AB_1856019, HPA024235: AB_1856020, HPA024691: AB_1856021" "unprognostic (3.22e-1)" "unprognostic (2.90e-2)" "unprognostic (2.45e-1)" "unprognostic (8.75e-3)" "unprognostic (1.64e-1)" "unprognostic (8.25e-2)" "unprognostic (3.71e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (7.73e-2)" "prognostic favorable (6.43e-4)" "unprognostic (1.14e-1)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (2.60e-1)" "unprognostic (1.00e-1)" "unprognostic (9.00e-3)" 30.1 23.6 39.1 23.2 45.8 17.1 43.9 41.0 49.3 22.2 32.0 21.1 16.5 26.8 25.1 18.5 16.7 21.7 32.4 37.9 46.7 23.5 32.8 19.5 33.5 43.1 44.8 21.7 18.0 48.0 19.7 30.8 44.2 31.0 20.7 58.2 22.7 21.8 68.5 16.3 18.9 27.5 43.5 28.3 24.0 18.8 43.7 37.3 25.8 52.4 40.3 23.1 15.2 50.7 45.5 57.5 59.6 33.3 60.9 60.5 31.2 58.3 44.5 61.8 58.5 51.4 19.7 98.3 46.0 61.2 35.0 35.9 87.8 50.0 86.4 60.7 75.0 60.9 73.1 39.4 56.4 41.3 37.9 47.2 33.3 59.6 76.5 37.7 54.4 49.9 52.3 48.3 54.2 32.7 66.1 30.4 26.8 25.8 24.9 61.2 70.8 32.4 30.6 43.1 25.3 39.4 52.4 52.8 49.5 52.3 95.9 17.2 46.9 53.1 24.2 52.6 69.6 26.9 31.0 52.4 41.2 62.3 37.5 14.9 21.1 22.4 25.0 22.7 21.9 80.4 19.5 24.0 22.6 96.7 24.6 21.5 30.4 22.6 50.9 35.0 20.0 16.6 39.1 45.8 41.0 49.3 37.9 46.7 43.1 44.8 44.2 43.5 43.7 50.7 36.4 35.3 45.1 57.5 53.8 24.0 30.1 17.0 25.6 51.5 87.3 46.0 91.1 14.3 32.9 18.4 39.6 39.7 47.2 18.6 41.1 30.4 7.6 19.8 55.5 37.9 16.3 58.3 123.7 23.8 35.0 38.5 23.4 25.3 12.6 47.0 34.2 31.7 89.8 35.3 115.9 17.1 30.5 32.1 38.2 6.0 33.8 36.5 30.2 90.9 32.8 89.7 63.8 78.4 114.1 28.3 65.5 28.2 28.2 52.8 16.5 38.1 19.0 52.5 26.3 34.3 47.7 82.2 75.7 25.5 20.3 25.9 34.4 61.2 18.9 33.6 RABEP2 "FLJ23282, FRA" ENSG00000177548 "Rabaptin, RAB GTPase binding effector protein 2" Q9H5N1 16 28904421-28936526 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047641 Approved Supported Vesicles,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 57: B-cells - Immune response" "Vesicles, Cytosol" "HPA047641: AB_2680111" "unprognostic (4.93e-2)" "unprognostic (1.21e-2)" "unprognostic (2.13e-2)" "unprognostic (7.06e-2)" "unprognostic (1.44e-1)" "prognostic favorable (5.84e-4)" "unprognostic (2.46e-1)" "unprognostic (1.42e-1)" "unprognostic (8.41e-2)" "unprognostic (6.13e-2)" "unprognostic (1.26e-3)" "unprognostic (5.86e-2)" "prognostic favorable (1.24e-6)" "unprognostic (7.50e-2)" "unprognostic (8.20e-2)" "unprognostic (1.08e-1)" "unprognostic (5.92e-3)" 7.3 21.5 7.3 25.1 8.8 11.5 9.3 8.2 9.2 11.0 10.7 15.0 16.8 8.4 2.7 18.7 7.0 6.6 16.8 6.5 7.9 19.2 10.6 10.1 46.7 10.7 8.5 6.3 17.9 11.5 16.4 5.3 8.4 28.6 4.6 3.5 17.5 7.0 6.5 23.6 28.3 3.4 7.9 47.9 14.4 6.2 8.2 5.3 13.9 3.2 9.4 12.5 12.3 8.5 13.5 21.1 5.6 10.5 3.3 4.7 10.1 15.5 9.2 10.9 10.7 15.9 12.0 27.7 23.7 6.5 4.4 17.8 2.2 9.9 2.1 9.5 9.9 10.5 17.0 21.7 6.5 7.7 32.1 7.9 8.0 13.5 2.4 6.3 15.5 7.4 4.9 9.7 8.5 31.9 9.5 17.8 7.3 5.4 11.4 33.6 5.1 17.4 7.5 17.5 8.6 11.1 7.6 34.8 7.0 1.2 27.6 15.9 27.5 16.4 8.4 12.1 15.6 15.3 5.0 20.7 17.3 18.2 12.6 0.9 2.8 2.4 3.5 2.9 2.4 12.1 2.5 3.2 3.7 15.0 2.2 2.1 0.7 5.5 3.3 2.2 2.2 2.8 7.3 8.8 8.2 9.2 6.5 7.9 10.7 8.5 8.4 7.9 8.2 8.5 11.5 3.2 10.0 4.9 42.4 5.1 14.7 14.6 17.6 11.1 13.3 11.0 1.9 11.5 12.9 20.2 35.5 26.1 21.0 35.0 17.6 16.0 0.7 9.2 8.2 14.2 17.3 6.5 4.8 20.9 7.1 9.0 23.0 10.0 18.4 12.1 7.9 4.2 12.4 15.2 6.5 33.7 18.3 8.4 11.3 1.3 4.1 10.5 10.6 9.4 11.6 8.6 22.6 5.0 8.4 20.0 44.1 6.4 21.4 15.4 32.3 11.6 8.0 43.4 13.1 7.9 9.6 4.3 6.0 16.6 8.4 22.0 14.5 22.6 26.7 19.0 RANBP2 "ADANE, ANE1, NUP358" ENSG00000153201 "RAN binding protein 2" P49792 2 108719482-108785809 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport, Ubl conjugation pathway" "RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018437, HPA023960, CAB034063, HPA049497, HPA051675, HPA067564" Supported Supported "Nucleoplasm,Nuclear membrane,Vesicles" NA NA 160000 "Cluster 38: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear membrane" "Nucleoplasm, Vesicles" "CAB034063: AB_2176784, HPA018437: AB_2620151, HPA023960: AB_2671385, HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (2.51e-1)" "unprognostic (3.99e-2)" "unprognostic (1.22e-1)" "unprognostic (4.37e-2)" "unprognostic (1.28e-2)" "unprognostic (9.30e-2)" "unprognostic (5.47e-2)" "unprognostic (2.91e-1)" "unprognostic (4.02e-2)" "unprognostic (2.54e-1)" "unprognostic (4.23e-1)" "unprognostic (5.23e-2)" "unprognostic (1.62e-2)" "unprognostic (8.74e-2)" "unprognostic (3.08e-1)" "unprognostic (3.40e-2)" "unprognostic (2.53e-1)" 20.3 24.3 8.6 16.3 11.6 42.1 19.7 14.4 17.1 18.1 20.3 15.6 13.4 17.7 20.5 14.3 14.6 13.7 14.9 11.8 9.4 18.1 17.4 14.0 18.6 9.2 8.1 24.4 20.2 30.1 21.5 16.5 9.5 20.9 15.2 26.5 16.4 17.2 30.3 17.2 13.4 15.2 8.6 15.0 17.6 21.3 8.2 23.3 28.4 23.6 18.0 16.9 12.1 12.2 40.5 24.2 34.1 31.0 38.7 34.5 32.9 35.5 28.0 28.7 25.1 60.7 18.9 63.2 26.8 37.2 35.3 33.1 58.9 36.9 41.5 38.9 28.5 65.9 30.3 43.2 22.5 77.9 21.3 29.1 27.5 44.9 34.7 28.3 44.5 27.1 71.9 34.0 38.4 22.3 34.8 31.6 43.0 20.3 28.7 32.3 52.3 30.7 25.3 49.6 49.4 22.6 31.5 26.7 34.7 20.4 17.2 35.4 53.5 29.8 39.6 21.2 40.2 27.9 44.4 55.8 23.1 34.4 23.5 5.4 2.6 2.7 3.7 1.7 4.1 2.7 3.0 3.4 2.2 2.7 2.9 3.3 3.9 2.2 3.6 2.6 2.7 1.4 8.6 11.6 14.4 17.1 11.8 9.4 9.2 8.1 9.5 8.6 8.2 12.2 54.5 76.9 85.3 48.6 91.5 55.7 34.5 39.1 61.5 51.2 34.1 25.8 103.9 38.6 63.0 58.8 73.0 28.8 96.1 28.9 1.9 34.7 77.3 83.6 65.3 55.7 106.4 50.5 125.5 50.9 17.5 56.5 68.3 142.1 84.9 52.2 31.4 56.6 47.9 32.0 92.2 59.5 44.7 44.9 80.7 32.9 38.5 114.0 48.0 55.3 57.0 20.0 34.0 44.2 80.0 41.5 29.9 56.1 118.4 44.1 28.8 15.6 67.0 40.5 46.0 56.9 59.0 78.3 65.4 53.3 67.8 40.6 104.8 25.3 38.3 38.7 RANBP6 ENSG00000137040 "RAN binding protein 6" O60518 9 6011025-6015625 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043748, HPA052684" Approved Supported Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Vesicles "HPA043748: AB_10796796, HPA052684: AB_2681913" "unprognostic (1.47e-2)" "unprognostic (8.86e-2)" "unprognostic (1.70e-1)" "unprognostic (6.01e-2)" "unprognostic (3.63e-2)" "unprognostic (1.30e-1)" "unprognostic (3.37e-1)" "unprognostic (3.21e-2)" "unprognostic (1.34e-1)" "unprognostic (8.22e-2)" "unprognostic (3.81e-2)" "unprognostic (1.89e-2)" "prognostic favorable (1.34e-7)" "unprognostic (2.42e-1)" "unprognostic (1.91e-1)" "unprognostic (3.04e-1)" "unprognostic (2.61e-1)" 8.6 11.4 8.3 12.9 8.8 31.0 11.4 11.5 12.4 7.7 18.4 7.1 7.5 8.8 7.0 7.9 7.3 7.6 12.4 9.3 10.8 13.4 15.2 8.4 17.0 11.2 9.7 9.6 7.8 13.6 5.0 8.9 11.9 9.7 7.1 21.6 8.6 8.5 16.3 9.9 8.6 10.3 9.2 13.1 11.1 5.9 10.0 19.6 12.0 16.1 16.2 8.7 5.6 10.3 25.1 13.6 27.2 23.4 23.6 18.6 14.6 30.9 21.9 26.8 21.6 7.5 7.7 33.5 8.4 24.7 13.1 14.0 24.2 28.2 29.7 80.1 13.9 88.3 53.0 15.6 13.9 34.2 17.9 20.2 15.2 16.5 16.3 21.1 31.3 30.1 6.9 27.3 25.8 8.4 24.3 54.8 12.3 9.0 11.0 25.6 16.7 15.7 28.1 17.6 13.2 19.9 14.7 11.0 8.7 22.3 17.7 23.0 37.6 25.1 14.9 12.4 29.4 16.3 27.8 31.5 14.4 19.8 9.3 5.1 4.5 3.7 2.6 6.3 2.5 2.5 3.8 2.8 2.7 1.9 4.4 4.2 1.3 2.8 5.2 3.1 5.2 2.9 8.3 8.8 11.5 12.4 9.3 10.8 11.2 9.7 11.9 9.2 10.0 10.3 11.3 9.6 8.1 8.8 11.5 10.3 6.6 10.1 13.1 18.0 8.1 5.6 24.4 8.6 16.3 11.0 2.1 8.8 12.0 4.1 7.9 8.6 1.6 12.2 16.5 13.1 9.5 8.6 15.9 10.9 4.1 8.3 16.8 17.7 10.8 10.1 10.0 13.7 4.4 11.8 19.0 3.2 2.0 10.5 6.0 1.2 6.5 7.2 1.8 8.4 7.2 15.9 9.2 3.0 20.5 7.5 3.8 6.8 11.8 5.7 1.8 12.5 8.7 23.1 0.0 11.6 10.2 10.1 9.3 9.8 9.5 6.6 13.3 12.7 4.8 7.3 RAPGEF1 "C3G, GRF2" ENSG00000107263 "Rap guanine nucleotide exchange factor 1" Q13905 9 131576770-131740074 "Plasma proteins, Predicted intracellular proteins" Neurogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 228.6" "Cell type enhanced" "Detected in all" "Horizontal cells: 131.2;Langerhans cells: 108.6;Microglial cells: 123.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006426, HPA075984" Enhanced Supported Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA006426: AB_1856070, HPA075984: AB_2686771" "unprognostic (1.00e-1)" "unprognostic (8.19e-2)" "unprognostic (2.12e-2)" "unprognostic (2.43e-2)" "unprognostic (2.34e-1)" "unprognostic (2.38e-1)" "unprognostic (4.11e-2)" "unprognostic (1.74e-1)" "unprognostic (5.50e-2)" "unprognostic (6.04e-2)" "unprognostic (1.94e-2)" "unprognostic (1.62e-1)" "prognostic favorable (1.18e-5)" "unprognostic (5.66e-2)" "unprognostic (1.99e-2)" "unprognostic (1.49e-1)" "unprognostic (3.73e-2)" 37.3 24.0 41.4 53.9 72.6 53.2 26.8 27.0 37.1 20.4 37.9 31.9 23.9 25.6 8.0 23.6 25.5 23.7 57.8 40.8 40.2 23.0 23.0 43.3 56.1 35.8 36.9 16.3 47.8 20.1 16.4 56.4 32.3 21.5 23.4 27.5 20.2 21.4 228.6 21.9 35.3 30.4 25.6 41.9 29.1 15.9 43.8 35.1 22.7 104.8 63.1 25.8 18.2 20.2 34.5 39.4 39.1 39.6 39.1 42.0 149.2 29.0 59.0 33.0 23.6 49.0 22.1 61.9 35.6 58.8 70.7 61.4 45.1 40.5 16.4 144.6 18.6 18.3 67.2 26.2 32.8 76.1 80.4 32.2 73.0 43.3 51.0 33.1 60.4 70.8 49.7 119.1 43.4 35.7 54.0 27.0 39.6 34.1 35.2 53.0 91.0 86.8 14.9 41.1 33.0 32.9 42.5 39.8 42.3 39.0 38.1 63.1 64.4 88.1 36.7 56.4 44.7 39.8 37.3 122.0 41.9 32.0 21.6 3.1 1.2 1.6 3.4 2.2 2.0 4.9 2.3 2.3 1.4 2.9 0.5 1.5 1.3 1.3 2.4 1.6 1.8 1.6 41.4 72.6 27.0 37.1 40.8 40.2 35.8 36.9 32.3 25.6 43.8 20.2 73.5 6.4 13.8 27.1 35.6 18.7 9.3 10.9 5.2 19.5 10.8 13.5 16.2 14.3 12.3 5.5 14.6 22.7 49.7 23.3 5.9 8.2 2.6 13.0 9.4 43.0 12.1 1.7 47.5 18.6 35.3 11.8 17.9 17.8 20.3 14.0 22.5 17.4 26.4 131.2 66.6 14.9 8.2 23.9 108.6 2.5 8.7 51.6 32.0 123.7 59.8 19.7 27.8 61.3 24.7 17.1 19.1 12.0 88.0 11.7 16.8 9.2 16.7 13.4 6.6 13.4 10.3 5.1 11.8 5.6 11.4 51.7 31.0 5.8 14.0 10.8 RBSN ZFYVE20 ENSG00000131381 "Rabenosyn, RAB effector" Q9H1K0 3 15070073-15099163 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044878 Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 59: Non-specific - Transcription" Vesicles "HPA044878: AB_10967610" "unprognostic (6.76e-2)" "unprognostic (2.18e-1)" "unprognostic (3.00e-3)" "unprognostic (1.00e-1)" "unprognostic (8.06e-2)" "unprognostic (3.79e-3)" "unprognostic (1.09e-3)" "unprognostic (1.72e-2)" "unprognostic (3.57e-1)" "unprognostic (1.90e-2)" "unprognostic (2.00e-2)" "unprognostic (9.34e-2)" "unprognostic (2.38e-3)" "unprognostic (4.45e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-1)" "unprognostic (1.78e-1)" 9.0 7.0 12.5 6.7 12.5 18.2 7.7 10.2 13.0 9.1 1.1 10.7 4.7 9.3 7.1 8.9 8.7 5.4 9.8 13.4 11.4 5.4 8.4 8.4 6.6 12.1 12.5 12.7 5.9 9.7 6.1 7.9 11.1 7.4 5.3 13.6 5.9 9.0 13.1 10.2 7.1 9.0 12.8 7.7 7.8 6.6 13.0 5.5 11.2 9.9 6.1 9.1 7.5 11.8 11.2 16.0 12.8 16.6 13.8 10.2 33.9 12.0 11.5 14.1 12.7 9.7 6.5 7.8 6.8 15.9 8.2 7.0 16.5 14.5 12.4 9.9 14.6 8.9 19.7 8.0 9.5 9.0 9.4 11.1 16.1 18.1 12.0 8.3 11.6 8.7 13.5 8.9 10.8 14.7 4.9 4.5 11.0 7.1 12.7 6.4 14.6 8.6 7.3 12.6 3.4 12.0 14.7 8.9 10.7 9.4 22.8 6.5 14.2 12.7 13.3 12.5 17.1 7.9 12.6 9.2 12.2 10.0 12.2 8.1 4.6 11.1 4.4 6.4 3.9 4.4 6.1 5.5 3.8 7.4 7.7 5.2 11.7 3.1 5.6 3.6 4.3 2.7 12.5 12.5 10.2 13.0 13.4 11.4 12.1 12.5 11.1 12.8 13.0 11.8 10.4 16.0 19.0 19.6 9.2 0.0 6.7 0.0 6.8 21.6 7.6 7.0 20.4 8.6 9.9 3.7 22.9 10.4 8.4 6.0 5.9 8.4 17.4 6.4 11.1 12.4 1.2 9.5 21.8 9.6 9.6 14.6 10.2 8.8 10.1 16.4 14.6 14.0 10.7 21.9 23.9 6.9 0.0 15.8 0.0 18.0 19.0 12.1 0.0 8.4 10.5 15.5 7.2 16.1 25.2 9.6 5.1 14.7 12.1 12.6 8.1 6.9 8.0 23.1 6.6 17.5 10.4 12.4 14.0 11.0 0.0 12.9 9.9 10.6 5.4 10.0 RNF13 RZF ENSG00000082996 "Ring finger protein 13" O43567 3 149812770-149962139 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 591.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 462.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064784 Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" Cytosol "HPA064784: AB_2685350" "unprognostic (1.27e-1)" "unprognostic (2.32e-2)" "unprognostic (1.03e-1)" "unprognostic (1.93e-2)" "unprognostic (1.80e-1)" "unprognostic (9.64e-2)" "unprognostic (8.49e-2)" "unprognostic (4.36e-3)" "unprognostic (1.72e-1)" "unprognostic (1.25e-1)" "unprognostic (6.94e-3)" "unprognostic (1.13e-1)" "prognostic favorable (2.00e-8)" "unprognostic (2.95e-1)" "unprognostic (4.11e-2)" "unprognostic (2.17e-1)" "unprognostic (1.79e-1)" 48.2 41.2 58.1 40.4 95.2 19.9 53.9 88.1 91.5 33.6 63.7 35.0 28.9 33.3 57.2 32.6 30.2 40.6 34.4 55.0 77.3 67.9 73.8 64.1 38.0 101.8 83.9 35.6 36.1 52.3 18.3 64.1 100.8 46.6 37.1 40.4 75.5 39.3 36.5 32.5 30.5 36.9 85.6 53.0 34.3 25.2 75.9 32.0 64.0 42.6 33.2 42.3 28.9 131.0 60.6 39.4 24.4 29.0 92.2 55.2 40.3 32.2 86.2 32.3 47.4 33.4 84.4 26.6 48.7 42.0 58.7 58.0 37.5 41.5 42.9 34.1 24.6 35.8 17.3 31.2 61.5 35.0 41.8 59.9 73.1 26.5 71.8 37.3 37.0 24.9 10.1 49.7 28.0 34.5 26.2 18.8 16.8 58.6 29.1 19.0 26.7 108.5 54.2 29.6 12.6 37.6 28.5 39.9 110.3 19.2 79.2 34.0 37.8 40.8 16.5 45.6 23.4 89.9 61.9 51.5 35.9 30.1 23.6 98.2 130.1 106.5 37.4 153.8 48.8 51.9 41.5 44.8 93.1 48.4 38.0 42.4 462.3 46.3 207.8 68.3 48.7 104.5 58.1 95.2 88.1 91.5 55.0 77.3 101.8 83.9 100.8 85.6 75.9 131.0 100.9 109.0 72.3 78.7 55.3 73.5 68.2 84.3 74.0 44.5 54.5 51.1 27.3 48.6 68.1 47.8 29.2 101.2 61.9 30.2 43.0 63.0 2.5 32.5 34.5 69.4 20.3 32.4 122.1 70.6 83.5 84.8 31.6 39.7 60.8 14.6 80.3 53.7 201.2 21.9 98.8 27.7 67.1 183.9 173.7 6.7 76.1 177.6 103.2 92.8 93.5 98.5 38.1 115.6 591.2 58.7 33.6 88.0 62.4 71.9 38.5 71.5 40.4 37.2 92.1 76.3 55.5 23.6 32.5 52.3 72.5 52.5 49.8 38.2 27.7 55.8 RNF144A "hUIP4, KIAA0161, RNF144, UBCE7IP4" ENSG00000151692 "Ring finger protein 144A" P50876 2 6917412-7068286 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.6;Inhibitory neurons: 101.7;Oligodendrocyte precursor cells: 194.5;Oligodendrocytes: 330.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.1" "Group enriched" "Detected in many" 7 "granulocytes: 6.1;T-cells: 2.4" "Cell line enhanced" "Detected in many" "HEL: 39.7;HMC-1: 127.9;SH-SY5Y: 39.0;SK-MEL-30: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049939 Approved Supported Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA049939: AB_2680960" "unprognostic (1.78e-1)" "unprognostic (2.53e-3)" "unprognostic (8.37e-2)" "prognostic unfavorable (6.00e-4)" "unprognostic (6.57e-2)" "prognostic favorable (6.96e-4)" "unprognostic (7.04e-6)" "unprognostic (1.20e-1)" "unprognostic (2.03e-2)" "unprognostic (5.64e-1)" "unprognostic (9.11e-2)" "unprognostic (1.92e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (7.32e-5)" "unprognostic (1.30e-2)" "unprognostic (3.01e-1)" "unprognostic (1.82e-3)" 9.7 28.5 21.1 4.1 46.1 13.9 10.1 59.2 36.7 24.2 1.2 5.7 2.6 26.3 7.7 4.3 7.8 7.1 8.1 17.5 24.0 7.3 1.3 5.4 6.0 30.1 27.0 19.3 30.7 38.1 12.9 5.9 33.4 9.1 5.3 23.0 4.6 6.4 9.6 5.4 3.8 11.6 21.5 23.0 2.6 4.7 30.3 7.5 3.4 10.1 5.6 4.4 7.5 73.6 0.8 5.8 30.1 6.2 6.6 13.6 23.0 0.2 0.0 1.1 2.8 0.1 0.7 2.9 3.3 0.3 8.7 0.7 10.0 0.0 0.0 1.6 2.6 39.7 0.3 11.8 0.3 0.7 127.9 21.7 0.1 2.2 0.0 0.0 0.0 9.9 17.3 0.6 0.0 4.9 20.6 1.7 11.0 0.7 13.6 15.9 21.8 2.6 1.0 10.2 9.9 39.0 0.5 4.0 39.8 3.9 1.7 2.6 0.1 3.9 10.0 10.7 4.5 10.4 3.5 0.1 14.7 8.7 14.3 1.3 0.0 6.1 1.2 0.0 1.8 0.0 1.3 0.9 0.1 0.1 2.4 1.7 0.3 0.5 0.0 0.0 0.6 0.4 21.1 46.1 59.2 36.7 17.5 24.0 30.1 27.0 33.4 21.5 30.3 73.6 27.8 3.2 4.2 34.3 2.4 2.4 0.7 0.0 1.8 4.6 2.5 2.5 11.5 2.8 1.9 0.0 75.0 2.4 5.3 15.4 1.9 3.3 5.5 6.1 15.4 13.9 25.4 18.5 176.6 5.8 3.1 10.4 2.6 10.7 8.9 31.5 23.2 1.1 4.9 10.1 101.7 2.7 0.0 1.0 1.7 14.2 4.4 1.7 24.9 17.8 1.2 7.6 10.3 194.5 330.3 3.0 11.1 10.5 3.1 3.0 2.0 0.3 1.5 39.8 0.0 16.1 5.2 1.8 6.6 5.2 1.6 1.1 9.8 19.1 2.7 1.7 RPTOR "KIAA1303, KOG1, Mip1, raptor" ENSG00000141564 "Regulatory associated protein of MTOR complex 1" Q8N122 17 80544819-80966371 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 46.0;Excitatory neurons: 70.1;Inhibitory neurons: 66.3;Microglial cells: 32.8;Oligodendrocyte precursor cells: 50.8;Oligodendrocytes: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013514, HPA064306" Approved Enhanced Vesicles,Lysosomes NA NA "Cluster 35: T-regs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Lysosomes" "CAB013514: AB_2533523, HPA064306: AB_2685240" "unprognostic (5.09e-3)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (1.90e-1)" "unprognostic (1.38e-1)" "unprognostic (9.75e-2)" "unprognostic (3.34e-3)" "unprognostic (1.17e-2)" "unprognostic (9.63e-2)" "unprognostic (8.80e-2)" "unprognostic (4.40e-3)" "unprognostic (8.46e-2)" "unprognostic (6.03e-2)" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (1.27e-2)" "unprognostic (1.77e-2)" 5.9 4.6 3.5 4.4 3.3 4.1 3.6 2.0 4.4 4.3 0.1 5.7 4.8 5.6 1.8 4.5 4.5 2.9 6.1 3.8 2.6 3.1 3.4 4.2 3.3 3.3 2.8 4.8 5.5 5.3 4.0 3.6 3.3 4.5 2.4 2.6 4.6 5.0 14.1 5.1 4.5 4.6 2.0 3.8 4.4 4.0 3.5 4.4 3.6 7.0 2.7 5.4 3.6 3.2 16.2 34.7 6.8 12.9 9.5 7.0 15.5 12.7 9.5 17.9 12.4 21.5 13.8 13.3 10.1 12.9 13.8 11.6 10.5 15.7 8.9 5.6 19.6 20.8 16.8 21.2 8.9 19.8 15.3 12.3 9.9 17.3 9.1 5.9 16.6 15.7 24.9 4.6 8.6 8.8 12.4 7.8 7.4 9.2 24.0 10.2 12.9 11.2 4.6 17.8 13.4 17.4 14.4 22.9 14.9 6.6 16.3 14.5 9.6 37.1 17.8 11.6 15.7 8.9 3.9 12.6 22.4 10.1 23.6 0.0 0.1 0.0 0.5 0.3 0.3 0.2 0.2 0.3 0.4 0.1 0.2 0.2 0.0 0.1 0.2 0.0 1.0 0.4 3.5 3.3 2.0 4.4 3.8 2.6 3.3 2.8 3.3 2.0 3.5 3.2 4.3 0.0 3.9 46.0 8.5 3.2 3.0 2.4 4.6 6.8 4.2 3.3 4.5 5.7 1.6 5.5 4.2 4.4 7.2 3.8 1.9 3.6 6.7 3.9 5.4 4.3 6.0 4.8 70.1 3.8 5.9 4.8 8.2 4.9 2.5 7.5 2.2 7.5 4.7 11.8 66.3 3.1 6.1 5.7 3.2 10.9 3.1 6.7 1.8 32.8 1.7 4.3 2.1 50.8 66.2 4.7 3.5 5.3 9.4 4.5 4.6 2.7 2.0 7.0 0.0 5.5 4.1 4.5 3.5 5.1 3.0 4.4 9.3 6.0 5.6 3.8 RRAGC "FLJ13311, GTR2" ENSG00000116954 "Ras related GTP binding C" Q9HB90 1 38838198-38859772 "Disease related genes, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 224.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018247, HPA055489" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Vesicles" "HPA018247: AB_1856475, HPA055489: AB_2682832" "unprognostic (2.04e-2)" "unprognostic (1.58e-1)" "unprognostic (2.63e-2)" "unprognostic (1.41e-2)" "unprognostic (3.40e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (9.97e-9)" "unprognostic (2.14e-1)" "unprognostic (3.61e-2)" "unprognostic (4.98e-2)" "unprognostic (2.23e-2)" "unprognostic (1.71e-1)" "unprognostic (5.13e-2)" "unprognostic (6.38e-2)" "unprognostic (2.69e-1)" "unprognostic (2.77e-1)" "unprognostic (3.82e-2)" 37.0 16.9 18.0 16.6 19.2 30.2 25.2 20.0 19.4 17.1 16.4 21.5 18.7 16.1 14.0 24.9 13.9 17.7 21.6 17.6 20.4 24.5 18.5 19.3 20.5 20.4 21.3 21.6 14.2 24.0 10.0 28.5 21.3 14.9 17.0 16.1 14.2 16.9 17.4 29.8 16.2 21.9 19.5 17.3 15.1 17.5 19.8 18.8 16.7 18.9 21.8 19.0 18.1 21.3 37.0 16.6 21.3 23.3 110.7 74.6 33.0 33.7 68.6 44.8 47.2 12.7 23.9 23.0 18.9 52.6 71.8 21.7 40.1 22.2 36.8 37.6 28.3 22.1 19.2 14.7 135.6 26.0 23.9 66.7 55.2 48.0 61.9 35.4 47.5 24.5 22.9 44.9 65.7 10.2 19.0 14.7 27.2 15.9 28.0 18.1 37.6 15.6 31.6 42.5 11.1 16.5 27.0 20.0 73.2 47.5 18.3 19.5 42.5 54.3 22.4 60.0 29.2 35.0 60.5 26.8 50.5 29.1 28.8 0.5 2.4 5.5 1.7 2.3 2.9 3.3 2.6 2.2 2.3 3.6 2.2 2.1 5.9 1.7 1.8 8.4 2.5 1.6 18.0 19.2 20.0 19.4 17.6 20.4 20.4 21.3 21.3 19.5 19.8 21.3 31.2 32.1 28.0 6.5 42.1 111.9 47.1 19.2 40.9 20.0 31.0 25.0 22.2 24.3 16.1 12.9 12.5 84.9 38.4 30.3 11.7 55.7 56.3 32.0 26.6 34.3 14.4 24.0 7.4 48.1 57.7 39.4 12.2 42.9 16.5 16.9 35.7 14.2 72.1 38.7 8.3 10.3 20.3 34.4 65.0 49.8 30.7 49.2 53.4 9.4 63.3 43.4 10.3 7.5 15.8 47.0 14.0 37.2 20.1 47.3 21.5 30.4 15.0 22.8 19.7 28.1 37.5 24.7 28.5 46.1 140.5 224.1 23.3 18.6 12.2 51.1 RRAGD "bA11D8.2.1, DKFZP761H171" ENSG00000025039 "Ras related GTP binding D" Q9NQL2 6 89364616-89412273 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 129.1;Distal tubular cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 3.3;monocytes: 2.4" "Cell line enhanced" "Detected in many" "Karpas-707: 63.9;SCLC-21H: 33.1;U-266/70: 80.0;U-266/84: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068664 Approved Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Vesicles, Centrosome" "HPA068664: AB_2686016" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.53e-3)" "unprognostic (1.09e-1)" "unprognostic (2.03e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.80e-4)" "unprognostic (3.75e-2)" "unprognostic (1.66e-2)" "unprognostic (4.33e-2)" "unprognostic (1.11e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.47e-8)" "unprognostic (8.41e-3)" "unprognostic (1.23e-1)" "unprognostic (9.46e-2)" "unprognostic (4.40e-2)" 9.8 9.1 14.0 2.3 18.9 11.6 8.2 31.8 16.1 9.4 17.9 4.0 1.7 1.5 6.9 13.8 13.7 3.6 38.4 15.9 13.9 26.5 4.4 7.0 2.8 16.4 12.2 1.6 6.4 22.7 11.4 3.2 17.2 6.1 1.8 21.8 52.2 2.8 84.5 6.7 2.0 2.1 21.5 4.8 1.7 6.9 14.8 5.5 28.1 60.3 2.5 5.8 6.2 23.8 0.1 1.7 4.4 3.3 0.4 0.0 0.3 0.0 0.0 0.5 0.9 0.1 0.1 0.0 1.5 0.0 22.6 0.1 24.5 0.1 0.0 0.0 12.1 5.8 0.1 0.1 1.8 16.9 19.0 0.4 1.5 0.0 0.1 0.0 0.0 16.9 0.5 63.9 0.1 1.8 8.2 8.4 3.6 0.0 1.8 16.8 23.1 0.2 5.8 0.6 33.1 1.8 0.6 2.2 28.8 1.3 0.7 13.2 0.0 1.8 2.8 11.5 3.0 80.0 39.8 0.0 6.1 12.5 1.9 2.6 0.6 1.4 0.0 0.5 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.3 3.3 0.1 2.4 0.3 0.0 0.1 14.0 18.9 31.8 16.1 15.9 13.9 16.4 12.2 17.2 21.5 14.8 23.8 1.4 9.6 16.7 5.2 3.7 16.2 17.0 5.8 4.0 21.7 17.4 9.7 129.1 17.2 13.9 14.7 31.3 0.6 4.7 0.1 117.4 20.2 25.6 10.4 2.5 4.8 1.2 5.0 17.6 16.9 1.5 10.0 1.1 15.0 4.5 2.9 2.5 9.7 51.9 47.1 20.6 0.5 42.7 25.8 9.2 15.5 3.1 23.2 39.2 3.7 10.4 29.6 0.0 13.0 17.2 8.1 0.0 4.1 8.0 28.4 0.0 18.6 19.4 16.3 0.0 11.8 7.0 21.7 30.3 32.4 22.6 0.7 3.9 0.2 0.2 30.2 RUBCN "KIAA0226, rubicon, rundataxin" ENSG00000145016 "Rubicon autophagy regulator" Q92622 3 197668867-197749727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Endocytosis, Immunity, Phagocytosis" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 67.5;Plasma cells: 48.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 87.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050908, HPA054497" Approved Supported Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Vesicles, Cytosol" "HPA050908: , HPA054497: AB_2682507" "unprognostic (2.91e-2)" "unprognostic (1.61e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (1.34e-3)" "unprognostic (1.46e-1)" "unprognostic (1.20e-2)" "prognostic unfavorable (9.91e-5)" "unprognostic (1.99e-1)" "unprognostic (6.71e-2)" "unprognostic (2.86e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (2.22e-2)" "unprognostic (2.92e-2)" "unprognostic (1.75e-1)" "unprognostic (2.43e-1)" "unprognostic (1.23e-1)" 8.3 7.5 16.2 11.6 16.3 8.5 7.2 10.5 17.0 9.2 4.4 10.4 7.3 8.8 4.0 12.0 8.5 7.2 11.4 17.0 19.0 7.7 5.6 11.8 15.3 20.0 17.8 10.7 9.1 6.8 15.8 5.8 15.9 7.4 5.7 10.9 7.3 7.2 8.9 9.1 13.1 7.8 14.5 19.2 8.1 14.6 23.7 8.8 7.1 8.1 16.1 8.9 8.4 17.4 30.9 7.4 8.2 16.2 14.4 8.3 8.6 13.8 9.2 17.0 14.2 12.7 8.4 33.6 26.7 15.8 16.1 17.0 15.0 8.0 13.6 9.3 13.9 21.6 13.4 4.9 8.4 12.0 18.0 7.0 9.6 14.8 17.6 7.9 10.7 14.4 12.3 87.7 11.5 24.4 15.7 7.5 7.1 8.8 23.2 14.9 8.6 22.6 9.6 13.9 34.3 7.9 10.2 19.8 10.8 5.5 29.2 8.1 13.7 9.9 9.9 27.8 18.9 36.5 34.2 27.0 13.6 22.4 8.7 0.8 2.6 17.5 3.7 3.9 2.4 7.7 3.1 4.7 1.6 8.5 2.2 3.2 2.9 1.8 4.8 16.6 4.4 1.7 16.2 16.3 10.5 17.0 17.0 19.0 20.0 17.8 15.9 14.5 23.7 17.4 8.5 6.4 11.2 0.0 33.9 0.0 6.0 0.0 8.0 21.0 7.3 7.0 0.0 7.2 4.3 12.9 18.8 1.8 28.9 3.8 1.9 5.8 21.7 4.8 6.2 6.7 0.0 5.7 0.0 6.4 3.7 4.8 7.1 9.8 2.5 6.1 9.3 3.5 9.2 21.9 0.0 3.7 0.0 16.3 0.0 16.4 5.0 18.7 0.0 0.0 67.5 15.0 14.4 0.0 0.0 8.5 1.5 6.4 48.3 8.9 5.8 2.7 0.7 14.3 6.6 9.7 6.8 34.1 21.3 5.6 0.0 6.4 15.9 4.9 2.8 12.3 RUFY1 "FLJ22251, RABIP4, ZFYVE12" ENSG00000176783 "RUN and FYVE domain containing 1" Q96T51 5 179550554-179610012 "Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038804 Approved Supported "Nuclear speckles,Vesicles,Cytosol" NA NA 25000 "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" "Vesicles, Cytosol" "Nuclear speckles" "HPA038804: AB_10673290" "unprognostic (3.17e-2)" "unprognostic (2.82e-1)" "unprognostic (9.24e-2)" "unprognostic (2.50e-1)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (2.04e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (9.74e-2)" "unprognostic (1.31e-1)" "unprognostic (2.73e-2)" "unprognostic (3.60e-1)" "unprognostic (2.08e-1)" "unprognostic (2.55e-1)" "unprognostic (5.85e-2)" 28.2 33.1 9.6 13.4 10.5 13.3 26.1 9.8 10.2 27.2 11.3 29.1 9.4 27.5 8.1 33.9 24.5 8.8 20.4 9.5 10.1 24.1 21.3 26.6 14.2 10.2 10.0 23.9 24.4 13.5 22.7 9.0 10.1 22.4 8.2 7.4 25.8 8.6 33.8 33.1 25.9 7.8 9.9 35.2 24.2 10.9 10.0 13.6 24.7 10.1 11.5 26.3 27.2 10.6 13.9 22.5 11.8 15.7 22.3 18.2 13.4 24.2 17.2 14.1 16.3 22.0 31.6 22.4 13.4 29.6 16.2 12.6 21.9 31.6 16.4 71.2 16.6 39.2 17.1 16.0 22.8 22.0 20.7 18.5 17.1 9.5 27.0 24.6 15.5 12.5 16.2 20.8 12.7 42.0 23.5 15.2 12.6 15.0 10.5 20.9 8.4 20.9 23.5 22.4 11.7 16.7 35.4 22.5 13.2 14.8 18.0 26.6 18.8 18.3 6.2 10.0 19.3 12.8 21.2 39.8 16.9 39.0 17.2 14.9 4.8 11.9 2.2 5.1 1.3 3.8 2.7 2.3 4.2 5.7 1.9 2.4 7.9 1.8 7.1 4.8 4.5 29.8 9.6 10.5 9.8 10.2 9.5 10.1 10.2 10.0 10.1 9.9 10.0 10.6 19.8 35.3 30.8 30.0 23.6 10.3 11.5 11.7 16.5 9.3 17.8 17.5 22.8 28.6 23.1 14.7 20.9 21.7 15.7 20.0 9.8 19.7 8.0 28.2 21.9 20.9 10.8 27.7 31.8 14.4 15.8 19.7 19.9 20.0 29.8 20.4 12.5 14.1 31.1 11.8 28.4 17.5 8.2 30.7 21.0 3.4 23.0 137.2 10.6 21.5 43.7 11.9 15.5 23.1 33.9 22.1 18.5 27.1 18.3 14.2 14.1 34.0 32.8 12.0 6.6 20.8 17.8 11.1 8.4 21.9 11.4 21.2 19.5 25.0 15.3 10.2 S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 236.1;Endothelial cells: 122.3;Hepatic stellate cells: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1248.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 73.0;HUVEC TERT2: 198.9;TIME: 113.3;U-251 MG: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" 114.7 14.4 58.8 29.8 62.7 18.5 91.9 59.8 59.0 18.5 27.8 19.5 9.4 24.7 3.9 26.8 22.9 28.0 71.8 51.3 65.1 18.0 31.3 78.3 46.3 65.2 73.0 8.2 20.3 23.3 8.7 48.1 61.3 13.7 10.1 14.6 15.0 7.8 27.9 17.9 22.3 31.2 57.6 63.1 17.1 2.6 76.5 21.4 35.9 51.5 26.9 34.3 19.2 52.6 15.6 0.2 14.2 0.0 1.4 32.7 0.1 73.0 13.5 47.9 16.6 0.1 0.7 0.0 17.8 25.2 0.4 0.0 1.8 0.8 27.0 6.1 1.2 6.8 0.3 0.0 6.6 0.0 3.5 45.0 0.3 0.1 3.7 1.7 198.9 5.8 0.2 14.4 13.5 0.0 20.6 0.0 3.9 0.4 4.8 0.0 13.4 0.5 0.1 0.0 0.0 0.1 0.7 0.0 0.2 0.9 0.0 0.2 113.3 6.8 2.9 2.0 147.1 1.3 0.0 1.0 0.7 0.0 0.4 1248.4 2.2 55.4 589.4 2.1 441.5 294.7 502.6 492.1 2.6 346.9 383.3 396.3 15.4 397.5 3.4 3.1 329.4 438.7 58.8 62.7 59.8 59.0 51.3 65.1 65.2 73.0 61.3 57.6 76.5 52.6 236.1 0.0 8.9 37.9 36.0 7.6 0.2 0.0 2.2 0.4 1.1 1.1 23.8 2.8 1.3 0.0 0.0 5.9 25.0 0.0 0.0 0.0 0.0 1.1 1.0 122.3 0.0 0.4 0.1 0.0 0.3 11.7 0.5 1.8 7.6 9.7 114.2 8.9 9.9 0.0 0.3 0.0 0.0 6.5 5.7 0.0 0.9 3.0 5.4 13.1 9.9 31.1 40.2 0.5 0.2 0.0 0.0 0.0 18.2 0.5 0.0 0.1 0.0 1.4 0.0 3.6 4.8 0.7 0.7 0.6 5.1 2.6 29.9 1.8 0.1 0.4 SAMD5 dJ875H10.1 ENSG00000203727 "Sterile alpha motif domain containing 5" Q5TGI4 6 147508690-147737547 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Bipolar cells: 96.0;Inhibitory neurons: 276.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 16.6;Hep G2: 65.6;K-562: 44.7;RH-30: 29.0;WM-115: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067811 Uncertain Supported Vesicles No No "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA067811: AB_2685901" "unprognostic (4.16e-2)" "unprognostic (4.52e-2)" "unprognostic (9.65e-3)" "unprognostic (1.41e-2)" "unprognostic (1.82e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (2.31e-1)" "unprognostic (1.54e-1)" "unprognostic (1.61e-2)" "unprognostic (8.55e-3)" "unprognostic (3.09e-2)" "unprognostic (5.40e-3)" "unprognostic (1.72e-1)" "unprognostic (4.51e-2)" "unprognostic (9.82e-3)" "unprognostic (1.50e-1)" 0.6 1.8 2.8 1.3 5.6 0.1 4.1 1.0 2.6 1.4 0.1 6.0 3.0 4.2 0.8 8.9 0.9 2.2 1.2 2.7 4.0 7.4 7.5 3.4 0.3 8.7 4.1 0.4 1.3 5.7 3.8 12.2 9.1 1.4 8.1 8.9 2.3 2.4 0.2 1.9 4.4 3.1 0.0 1.4 4.5 7.6 7.2 0.1 2.1 0.1 0.7 1.5 1.9 0.8 11.2 1.4 1.4 2.0 0.0 0.0 0.1 3.6 1.3 0.3 0.2 16.6 0.1 0.6 3.6 0.0 0.6 0.1 0.3 2.5 0.4 0.0 2.0 0.8 1.5 65.6 0.2 0.0 1.3 0.0 0.1 0.3 0.1 0.0 6.8 0.0 44.7 0.6 4.8 0.1 0.0 0.0 0.1 8.4 2.8 0.0 29.0 6.5 0.1 2.3 0.5 0.1 0.9 0.2 2.8 0.3 0.0 0.0 4.9 0.5 1.5 0.5 1.3 0.1 1.1 0.0 0.1 0.1 20.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 5.6 1.0 2.6 2.7 4.0 8.7 4.1 9.1 0.0 7.2 0.8 1.7 3.2 5.9 1.3 1.0 1.8 5.6 0.5 2.2 96.0 2.9 23.5 2.6 0.0 0.0 18.4 2.1 0.2 0.0 5.4 9.8 2.2 0.5 1.1 10.7 11.1 16.9 0.0 15.7 0.2 0.3 6.9 19.4 1.8 0.0 7.0 6.1 28.1 0.8 0.0 276.9 11.6 0.0 1.0 1.4 1.3 0.3 0.7 0.0 45.0 0.0 9.2 0.0 5.5 0.9 0.6 3.4 3.4 0.1 3.0 5.2 19.7 0.0 4.0 0.0 3.1 2.0 0.5 0.2 36.4 1.6 0.3 0.5 3.6 25.7 4.2 SAYSD1 "C6orf64, FLJ11101" ENSG00000112167 "SAYSVFN motif domain containing 1" Q9NPB0 6 39104063-39115186 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 55.5" "Group enriched" "Detected in many" 4 "Early spermatids: 136.1;Late spermatids: 63.2;Spermatocytes: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007959 Approved Supported Vesicles NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 23: Testis - Cell cycle regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA007959: AB_1078359" "unprognostic (2.65e-1)" "unprognostic (1.49e-2)" "unprognostic (2.03e-2)" "unprognostic (2.58e-1)" "unprognostic (3.70e-1)" "unprognostic (2.56e-1)" "unprognostic (9.90e-3)" "unprognostic (1.96e-2)" "unprognostic (6.50e-2)" "unprognostic (1.82e-3)" "unprognostic (5.08e-2)" "unprognostic (9.90e-2)" "unprognostic (2.54e-2)" "unprognostic (1.79e-1)" "unprognostic (9.78e-3)" "unprognostic (2.27e-1)" "unprognostic (2.00e-3)" 8.8 7.9 7.8 6.5 8.4 7.6 10.5 8.3 10.3 8.6 8.0 8.7 9.9 8.4 11.1 7.5 8.6 6.9 8.3 8.2 8.3 9.6 10.1 7.0 10.3 8.0 8.1 8.8 11.1 7.7 6.3 6.7 8.1 9.2 7.8 6.8 12.6 8.2 7.0 7.4 9.4 6.8 8.1 7.5 7.8 55.5 8.1 17.0 8.7 7.0 9.4 7.2 6.9 9.6 14.8 9.4 8.3 9.9 13.4 17.7 8.6 6.7 7.3 7.9 8.3 13.6 10.2 13.4 9.4 8.8 11.2 9.9 7.3 6.3 8.3 8.5 13.2 8.8 5.5 11.9 10.9 10.1 12.7 12.3 15.4 3.1 7.8 5.6 7.4 19.9 15.1 7.9 9.0 20.4 16.1 16.6 7.2 9.7 4.8 2.3 10.1 5.4 16.7 10.3 23.3 9.4 11.6 10.0 10.9 6.6 16.4 13.1 9.7 10.4 7.5 3.2 8.8 0.2 4.3 16.2 6.0 14.4 7.8 10.6 10.8 24.9 14.0 15.1 16.0 16.4 15.2 12.8 11.4 18.5 21.0 17.9 5.2 15.8 15.8 9.0 22.2 12.1 7.8 8.4 8.3 10.3 8.2 8.3 8.0 8.1 8.1 8.1 8.1 9.6 19.3 3.2 6.0 4.6 11.4 15.4 13.2 29.1 8.6 6.4 26.4 21.8 18.8 21.5 17.0 18.4 8.4 33.1 8.3 10.5 17.6 22.9 136.1 22.8 14.0 11.2 8.4 13.5 3.2 21.8 32.7 16.8 4.6 19.0 8.2 13.8 6.4 23.3 26.8 6.7 4.2 16.5 2.0 13.9 15.7 63.2 20.5 13.2 12.4 0.0 11.9 15.5 12.3 9.0 6.3 15.9 9.7 19.2 5.3 22.6 21.8 28.3 19.2 4.1 6.6 13.1 17.3 223.6 14.5 11.6 16.6 12.3 12.8 10.2 20.1 14.9 SCAMP2 ENSG00000140497 "Secretory carrier membrane protein 2" O15127 15 74843730-74873365 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014699, HPA019194" Approved Supported "Golgi apparatus,Vesicles" NA NA 71000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "HPA014699: AB_1856605, HPA019194: AB_1856604" "unprognostic (1.74e-1)" "unprognostic (1.27e-2)" "unprognostic (2.05e-1)" "unprognostic (5.23e-3)" "unprognostic (2.89e-1)" "unprognostic (1.38e-1)" "unprognostic (1.53e-2)" "unprognostic (7.23e-2)" "unprognostic (9.73e-3)" "unprognostic (7.26e-2)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic favorable (1.12e-6)" "unprognostic (3.40e-1)" "unprognostic (1.79e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-2)" 43.1 46.7 27.8 40.3 32.8 51.5 40.7 31.9 31.2 40.5 38.8 76.0 75.7 36.9 36.9 103.4 47.4 35.4 32.4 26.1 29.8 44.9 42.0 49.6 47.9 40.7 30.9 26.5 54.5 85.6 29.4 48.9 36.7 35.5 72.7 4.7 92.7 32.4 34.2 68.3 80.1 33.6 33.6 66.8 64.9 36.2 33.3 33.0 38.3 18.9 53.4 38.1 49.4 35.4 44.7 57.3 24.2 37.6 72.0 37.2 72.0 45.0 56.6 46.9 50.1 83.0 102.6 36.5 57.8 68.1 67.7 157.8 72.3 55.9 19.4 145.8 71.1 92.8 31.2 57.6 54.3 48.0 170.9 48.0 97.6 44.4 32.0 37.0 46.0 42.0 31.3 67.5 33.3 68.1 24.6 55.3 24.1 111.0 36.6 42.6 22.3 126.4 54.0 63.1 24.9 25.0 36.7 64.3 42.4 35.4 88.5 76.3 43.4 40.2 23.9 43.8 53.0 46.1 73.2 37.6 37.8 112.2 30.2 118.3 111.3 90.0 94.1 106.9 76.1 80.8 85.3 95.9 81.8 70.9 69.4 75.8 74.4 83.8 119.3 128.7 105.3 120.8 27.8 32.8 31.9 31.2 26.1 29.8 40.7 30.9 36.7 33.6 33.3 35.4 36.0 73.7 31.7 17.9 49.5 17.5 41.7 40.5 19.4 6.8 28.0 24.8 14.4 24.3 53.1 40.5 2.1 156.9 63.4 116.8 15.6 67.4 132.3 30.8 22.0 36.2 37.3 29.0 7.7 92.8 61.9 37.2 54.0 40.6 79.2 31.3 26.4 27.7 164.7 6.7 6.1 77.5 42.7 78.3 44.5 56.2 32.0 77.0 32.0 21.5 56.9 41.4 63.8 12.1 17.9 96.1 75.5 23.0 73.1 54.0 105.7 48.1 52.6 8.4 26.3 25.6 35.8 47.1 35.3 39.6 22.3 136.4 55.1 40.0 64.2 58.5 SCAMP3 C1orf3 ENSG00000116521 "Secretory carrier membrane protein 3" O14828 1 155255979-155262430 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071167 Supported Vesicles NA NA 75000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA071167: AB_2686352" "unprognostic (4.31e-2)" "unprognostic (1.30e-2)" "unprognostic (1.07e-2)" "unprognostic (2.17e-2)" "unprognostic (5.33e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (2.92e-5)" "unprognostic (8.78e-2)" "unprognostic (1.40e-1)" "unprognostic (1.06e-1)" "unprognostic (2.65e-1)" "unprognostic (3.74e-2)" "unprognostic (8.46e-3)" "unprognostic (1.60e-1)" "unprognostic (4.79e-1)" "unprognostic (1.07e-1)" "unprognostic (7.18e-2)" 45.1 69.6 4.6 7.1 6.8 7.9 43.5 6.3 8.2 38.1 4.5 37.4 7.7 35.2 0.2 49.9 31.9 5.0 65.0 5.0 4.5 49.0 48.4 40.9 12.1 6.3 5.2 34.9 51.9 4.7 33.8 7.3 5.6 37.0 2.4 1.1 49.3 6.1 90.9 56.4 38.4 3.5 6.4 46.5 47.0 28.3 5.4 8.3 38.6 3.2 7.2 39.5 38.6 8.2 19.7 30.2 11.2 8.8 8.3 6.8 14.5 21.6 20.7 26.3 19.4 30.0 15.7 45.1 49.3 10.9 15.7 20.5 9.0 18.7 1.8 29.8 68.3 25.7 11.7 8.5 26.1 30.5 17.4 9.7 20.9 21.2 10.3 3.3 18.9 49.3 38.2 18.3 11.6 38.3 50.5 14.6 16.5 27.9 59.4 43.1 9.1 67.5 4.8 13.1 8.3 20.0 26.2 8.0 39.1 3.4 32.1 13.7 29.0 20.9 17.5 29.3 29.6 43.3 84.8 52.9 16.7 41.1 15.2 41.0 47.5 52.8 94.4 51.7 86.8 98.8 91.3 91.1 58.1 100.3 83.3 86.6 6.7 76.0 71.4 102.4 101.0 100.9 4.6 6.8 6.3 8.2 5.0 4.5 6.3 5.2 5.6 6.4 5.4 8.2 23.0 16.0 37.1 12.4 33.8 38.2 23.8 57.3 54.1 18.5 27.3 19.3 39.1 30.0 43.7 33.1 4.2 86.4 27.2 19.0 9.8 49.0 1.7 16.3 20.8 33.1 30.1 14.5 9.9 69.4 55.1 27.1 27.0 26.3 25.3 16.6 32.9 37.9 57.3 18.5 11.9 24.3 42.7 21.3 26.7 5.3 17.1 23.0 24.9 7.5 41.3 20.2 30.9 9.5 17.4 48.5 19.9 18.8 56.1 24.7 36.8 24.4 22.6 10.9 13.1 16.7 27.3 20.0 5.5 46.7 40.1 71.3 33.4 20.5 30.1 22.5 SCG3 "FLJ90833, SgIII" ENSG00000104112 "Secretogranin III" Q8WXD2 15 51681492-51721026 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 133.5;choroid plexus: 40.1;pituitary gland: 39.4;retina: 56.8" "Group enriched" "Detected in many" 4 "Astrocytes: 79.3;Bipolar cells: 120.4;Cone photoreceptor cells: 102.2;Enteroendocrine cells: 148.4;Excitatory neurons: 46.2;Horizontal cells: 148.0;Inhibitory neurons: 64.0;Ionocytes: 38.7;Oligodendrocyte precursor cells: 63.3;Rod photoreceptor cells: 93.3" "Group enriched" "Detected in many" 7 "glioma: 41.0;pancreatic cancer: 15.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "NTERA-2: 50.5;SCLC-21H: 121.2;SH-SY5Y: 57.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006880, CAB033274, HPA053715" Enhanced Supported Supported Vesicles "Secreted in brain" NA NA 3100000 "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" Vesicles "CAB033274: AB_2302033, HPA006880: AB_1079898, HPA053715: AB_2682239" "unprognostic (1.38e-2)" "unprognostic (2.42e-1)" "unprognostic (1.40e-1)" "unprognostic (5.24e-5)" "unprognostic (1.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.74e-1)" "unprognostic (9.93e-2)" "unprognostic (1.40e-1)" "unprognostic (2.46e-1)" "unprognostic (1.71e-2)" "unprognostic (8.17e-2)" "unprognostic (1.03e-1)" "unprognostic (2.78e-1)" "unprognostic (2.78e-1)" "unprognostic (8.88e-2)" "unprognostic (1.27e-1)" 0.5 16.7 71.0 1.1 87.0 0.6 0.5 85.8 133.5 0.1 40.1 1.8 2.3 0.2 0.3 0.3 0.3 0.2 0.2 88.2 112.7 0.2 0.2 0.6 0.4 68.7 75.8 0.1 15.6 0.2 39.4 0.1 68.9 0.3 2.0 56.8 0.2 0.0 0.1 0.6 2.0 0.5 71.9 0.2 9.9 2.6 79.8 0.5 1.0 0.0 0.2 0.2 0.2 71.6 0.2 0.1 4.8 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.2 0.2 0.3 0.5 0.0 0.6 0.4 0.1 0.0 0.1 0.1 0.5 0.1 0.3 0.1 0.0 0.3 3.0 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.2 0.8 0.0 0.3 0.1 0.1 50.5 0.1 0.2 0.3 0.1 0.4 0.0 0.5 121.2 57.5 0.2 0.4 0.2 15.5 0.1 3.8 0.1 0.3 0.7 0.2 0.2 0.4 0.2 0.4 0.7 0.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 71.0 87.0 85.8 133.5 88.2 112.7 68.7 75.8 68.9 71.9 79.8 71.6 0.2 0.0 0.0 79.3 0.0 0.3 0.0 0.3 0.0 120.4 0.0 0.1 0.2 0.0 0.1 0.0 102.2 0.0 0.0 0.2 1.9 0.4 20.0 0.0 0.0 4.3 148.4 0.0 46.2 1.0 0.1 4.1 0.0 0.0 0.0 0.0 1.8 0.0 0.4 148.0 64.0 3.4 38.7 0.0 0.3 11.3 0.0 0.1 1.8 7.5 6.7 19.2 0.0 63.3 8.9 5.3 0.0 0.4 0.0 0.4 0.1 0.0 0.8 93.3 0.0 0.4 0.2 13.8 5.8 0.0 0.0 0.0 0.0 0.2 0.3 0.3 SEC13 "D3S1231E, npp-20, SEC13L1, SEC13R" ENSG00000157020 "SEC13 homolog, nuclear pore and COPII coat complex component" P55735 3 10293131-10321112 "Metabolic proteins, Predicted intracellular proteins, Transporters" "ER-Golgi transport, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035292, HPA057943" Approved Supported Nucleoplasm,Vesicles NA NA 35000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA035292: AB_10959451, HPA057943: AB_2683560" "unprognostic (3.33e-3)" "unprognostic (6.16e-2)" "unprognostic (2.28e-2)" "unprognostic (4.95e-2)" "unprognostic (4.22e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.73e-4)" "unprognostic (2.43e-1)" "unprognostic (2.67e-1)" "unprognostic (1.69e-1)" "unprognostic (4.58e-1)" "unprognostic (1.17e-1)" "unprognostic (1.40e-1)" "unprognostic (4.60e-1)" "unprognostic (2.43e-1)" "unprognostic (2.03e-1)" "unprognostic (8.33e-2)" 62.1 71.5 51.0 61.8 55.6 58.4 58.9 55.9 57.6 83.7 59.2 68.8 114.7 66.4 59.4 72.6 57.4 47.5 71.1 52.2 57.2 67.4 92.1 64.3 54.6 54.6 54.6 52.6 85.2 64.6 109.2 68.5 55.2 53.8 65.7 21.2 96.2 64.9 111.5 62.7 96.6 76.6 54.3 59.4 67.3 39.4 54.2 70.3 57.6 87.3 65.4 69.9 59.2 58.2 122.6 182.1 142.9 55.2 228.0 251.6 474.4 243.8 296.1 279.3 319.8 150.3 97.6 110.7 109.6 390.1 156.8 49.0 186.4 218.3 142.4 97.8 194.5 136.2 137.3 363.7 311.8 156.7 115.5 224.7 173.1 292.6 181.5 205.6 337.0 146.2 148.4 159.8 219.5 250.2 153.8 169.9 160.9 158.0 218.7 148.1 102.4 198.2 172.4 90.2 80.3 99.4 107.3 98.7 101.3 119.3 127.5 150.8 253.6 114.2 130.2 172.6 213.3 131.7 198.4 258.6 215.5 217.5 193.0 127.3 163.2 106.6 84.4 144.9 94.6 96.5 83.6 82.1 222.5 82.6 68.0 71.2 105.8 93.9 116.4 198.3 106.1 176.5 51.0 55.6 55.9 57.6 52.2 57.2 54.6 54.6 55.2 54.3 54.2 58.2 23.9 48.1 61.9 14.0 45.8 39.4 50.4 73.6 31.3 16.2 29.5 26.4 40.2 30.0 68.3 27.6 10.4 119.9 36.5 60.1 66.5 79.3 25.6 31.8 44.0 51.0 41.4 33.0 17.3 109.2 166.6 74.1 73.9 47.1 43.1 35.5 33.9 57.3 104.9 11.8 13.7 108.2 50.8 33.0 46.7 10.2 53.4 45.0 26.6 12.2 64.2 37.4 35.0 11.6 12.6 81.8 56.1 52.6 203.2 52.4 187.5 112.0 64.5 21.1 13.1 37.7 63.6 54.9 38.9 43.7 40.2 168.6 36.5 35.8 74.2 62.3 SEC23B "CDA-II, CDAII, CDAN2, HEMPAS" ENSG00000101310 "SEC23 homolog B, COPII coat complex component" Q15437 20 18507520-18561415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008216, HPA069974" Uncertain Supported Vesicles NA Yes 16000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA008216: AB_1079895, HPA069974: AB_2686223" "unprognostic (4.47e-2)" "unprognostic (2.67e-2)" "unprognostic (3.52e-1)" "prognostic favorable (8.25e-4)" "unprognostic (1.24e-1)" "unprognostic (1.33e-1)" "unprognostic (5.44e-3)" "unprognostic (6.01e-2)" "unprognostic (1.39e-1)" "unprognostic (8.75e-2)" "unprognostic (1.97e-1)" "unprognostic (9.97e-2)" "unprognostic (3.91e-2)" "unprognostic (1.72e-2)" "unprognostic (4.26e-2)" "unprognostic (2.81e-2)" "unprognostic (8.21e-2)" 19.6 38.3 18.7 32.0 27.1 36.0 37.8 24.7 25.9 36.2 27.4 31.6 23.8 17.2 53.8 28.4 29.5 23.1 8.5 19.5 22.4 37.4 30.6 29.7 30.5 27.2 23.8 16.9 57.1 50.6 32.6 24.2 27.2 34.8 32.7 40.7 70.9 35.9 4.1 18.2 23.3 18.5 24.5 25.5 38.2 34.8 23.2 27.6 59.5 6.2 38.0 30.5 12.6 38.9 85.0 93.9 49.8 48.7 32.3 36.6 116.0 69.8 45.3 80.0 68.7 84.9 73.8 37.5 44.9 50.4 107.0 88.5 88.5 120.7 86.2 47.5 43.1 64.9 35.6 130.6 70.5 90.2 78.7 28.0 71.8 118.0 151.4 47.6 50.6 34.0 74.8 82.4 55.1 90.7 59.8 49.5 48.0 118.9 101.6 62.4 77.7 122.1 83.0 85.6 78.8 58.0 83.6 188.9 80.6 62.6 82.3 94.4 45.3 53.1 29.8 58.4 87.1 104.2 155.9 60.1 45.3 47.8 74.4 147.9 94.1 106.0 57.2 95.6 78.7 67.2 56.8 61.4 107.9 61.2 51.3 54.0 48.0 78.8 94.9 80.7 75.4 103.7 18.7 27.1 24.7 25.9 19.5 22.4 27.2 23.8 27.2 24.5 23.2 38.9 8.5 16.0 43.5 15.3 24.7 11.5 21.0 34.3 10.2 21.0 21.5 15.6 3.0 20.0 42.5 31.3 16.7 34.3 36.0 26.2 58.7 36.1 95.6 25.4 12.4 11.3 19.7 7.4 17.9 33.4 30.0 11.7 25.0 31.3 15.9 13.6 11.0 25.6 42.9 13.5 20.5 34.7 26.4 38.7 21.0 11.3 14.3 30.3 23.2 15.0 33.1 23.9 9.2 23.1 27.0 31.8 24.2 10.5 59.0 30.1 11.8 53.2 45.4 20.4 19.7 12.4 12.2 48.7 22.1 15.8 14.2 65.8 21.0 16.0 21.5 28.3 SEC24C KIAA0079 ENSG00000176986 "SEC24 homolog C, COPII coat complex component" P53992 10 73744372-73772161 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA040196, HPA040213" Supported Supported Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040196: AB_10796449, HPA040213: AB_10796451" "unprognostic (5.06e-2)" "unprognostic (1.00e-2)" "unprognostic (2.17e-1)" "unprognostic (3.54e-1)" "unprognostic (8.46e-2)" "unprognostic (7.23e-2)" "unprognostic (9.06e-2)" "unprognostic (4.55e-2)" "unprognostic (1.64e-1)" "unprognostic (2.46e-2)" "unprognostic (1.02e-1)" "unprognostic (1.35e-1)" "unprognostic (7.71e-2)" "unprognostic (8.34e-3)" "unprognostic (2.11e-1)" "unprognostic (3.35e-2)" "unprognostic (1.77e-2)" 27.8 42.9 20.1 31.6 21.2 16.2 27.4 23.1 26.8 42.5 20.7 34.2 27.4 36.4 33.2 69.0 30.7 24.0 34.5 20.4 21.2 29.8 45.8 30.5 31.4 21.4 20.1 33.2 34.9 50.5 45.4 36.4 20.9 37.7 27.6 29.1 36.9 31.1 49.7 35.8 31.7 32.1 18.3 37.1 34.1 27.7 22.7 35.2 34.0 33.9 43.3 35.5 38.8 23.0 72.7 71.8 55.6 99.9 59.2 48.3 45.6 53.6 90.4 70.4 65.7 67.2 47.9 57.3 43.3 72.0 48.1 61.4 78.3 70.7 60.4 76.6 55.6 53.1 50.5 71.2 47.0 80.7 71.1 41.5 76.8 61.8 76.4 89.2 73.6 44.6 64.1 80.8 69.9 64.7 60.4 55.3 34.8 68.3 259.2 65.2 45.0 47.0 46.5 40.8 20.0 51.7 41.9 144.6 60.1 51.7 106.3 70.6 72.7 29.5 53.1 57.7 62.5 82.0 85.9 84.0 84.0 80.8 35.0 28.2 15.8 13.6 27.4 21.4 35.5 12.6 16.2 21.6 18.1 9.4 11.7 15.8 11.5 22.4 19.1 14.8 10.9 22.7 20.1 21.2 23.1 26.8 20.4 21.2 21.4 20.1 20.9 18.3 22.7 23.0 12.1 35.3 28.6 16.3 11.6 8.7 4.7 11.5 6.2 15.1 17.0 14.9 2.3 14.3 17.6 14.7 16.7 17.8 18.6 24.7 3.9 15.1 8.8 10.9 13.0 11.0 19.2 5.9 14.6 19.4 16.4 9.7 19.9 17.0 22.2 20.1 16.4 19.9 17.1 15.2 15.7 18.4 8.2 11.7 8.4 6.0 11.8 12.4 5.4 6.5 12.3 10.3 17.5 14.1 16.8 23.8 14.4 11.7 21.9 10.8 20.0 10.4 8.2 14.7 6.6 10.0 9.7 10.3 8.3 11.5 11.4 25.2 16.9 14.7 16.1 10.9 SEC31A "ABP125, ABP130, KIAA0905, SEC31L1" ENSG00000138674 "SEC31 homolog A, COPII coat complex component" O94979 4 82818509-82901166 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005457 Approved Supported Vesicles,Cytosol NA NA 40000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cytosol" "HPA005457: AB_1079896" "unprognostic (3.50e-2)" "unprognostic (2.28e-3)" "unprognostic (2.55e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-1)" "unprognostic (6.52e-2)" "prognostic unfavorable (3.32e-4)" "unprognostic (6.14e-3)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "unprognostic (4.21e-3)" "unprognostic (3.62e-1)" "unprognostic (1.64e-1)" "unprognostic (5.53e-3)" "unprognostic (2.92e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.69e-4)" 98.7 103.3 52.2 78.4 54.3 119.4 111.4 62.4 70.1 145.5 94.9 107.1 124.2 119.7 162.1 92.6 90.9 122.1 110.7 54.0 61.4 133.6 174.8 96.2 88.2 58.4 58.7 152.8 192.6 116.4 108.4 143.2 58.7 113.4 127.2 87.9 134.0 111.3 96.8 107.8 111.0 131.5 50.9 76.5 110.1 77.8 54.4 93.8 168.0 85.6 102.1 113.1 94.1 63.9 146.2 65.2 183.6 130.4 318.9 394.5 133.3 264.8 295.4 146.0 179.2 113.2 182.3 188.3 113.7 532.2 84.6 68.1 183.3 176.2 200.4 193.4 72.7 115.3 110.5 302.1 316.4 124.4 140.7 380.5 217.7 223.5 254.3 251.2 240.5 83.8 178.4 181.1 264.2 128.6 164.9 99.6 126.1 154.0 58.3 121.2 100.1 140.3 237.2 83.0 118.6 131.2 105.7 180.7 174.9 184.8 142.1 137.8 248.2 190.7 98.9 169.0 168.8 135.1 62.4 256.7 190.6 147.8 224.2 84.3 66.9 51.2 65.1 74.0 80.5 60.0 57.6 64.3 73.3 50.0 56.9 54.6 19.2 89.9 83.1 61.1 52.7 71.8 52.2 54.3 62.4 70.1 54.0 61.4 58.4 58.7 58.7 50.9 54.4 63.9 62.6 105.8 85.3 50.9 58.1 60.5 60.5 64.1 56.9 52.3 54.5 43.7 85.5 51.5 109.8 47.8 54.2 57.3 61.0 62.8 27.4 65.8 30.6 90.1 164.6 65.0 38.3 41.2 61.0 71.2 85.3 125.2 100.9 119.7 75.2 241.0 65.0 94.0 45.9 42.1 60.0 99.4 50.8 51.2 55.3 19.3 139.1 63.8 51.6 67.5 60.4 36.5 38.1 74.9 72.6 67.5 46.3 126.0 152.2 76.3 121.0 65.9 100.5 66.9 52.6 86.5 98.9 30.3 34.6 62.2 74.2 81.5 55.4 78.9 54.9 101.1 SEC31B "DKFZP434M183, SEC31B-1, SEC31L2" ENSG00000075826 "SEC31 homolog B, COPII coat complex component" Q9NQW1 10 100486646-100519864 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 28.7;Bipolar cells: 32.2;Cone photoreceptor cells: 39.6;Excitatory neurons: 38.1;Horizontal cells: 40.4;Inhibitory neurons: 40.7;Oligodendrocyte precursor cells: 32.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 9.1;JURKAT: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035882, HPA040819, HPA060052" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 59: Non-specific - Translation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Vesicles, Cytosol" "HPA035882: AB_10795246, HPA040819: AB_10794151, HPA060052: " "unprognostic (1.23e-1)" "unprognostic (3.13e-3)" "unprognostic (3.39e-3)" "unprognostic (1.03e-2)" "unprognostic (4.85e-2)" "unprognostic (1.42e-3)" "unprognostic (1.97e-3)" "unprognostic (6.63e-2)" "unprognostic (2.22e-1)" "unprognostic (2.25e-2)" "unprognostic (1.10e-4)" "unprognostic (8.23e-3)" "prognostic unfavorable (6.41e-7)" "unprognostic (2.31e-2)" "unprognostic (2.54e-1)" "unprognostic (1.79e-1)" "unprognostic (1.01e-4)" 2.2 1.5 2.0 1.1 2.0 2.5 2.0 2.3 2.9 2.6 1.2 2.5 0.3 2.1 1.0 0.8 2.6 0.8 2.8 1.8 1.9 2.2 2.0 1.7 1.6 1.9 1.7 2.8 0.6 1.7 3.7 0.7 1.8 2.3 0.8 1.5 1.6 0.8 5.9 1.3 2.3 0.8 1.5 3.0 1.7 2.7 1.9 2.9 2.0 8.3 1.3 1.8 1.5 2.2 0.1 0.0 2.0 0.5 0.6 1.0 0.1 0.4 0.9 0.2 0.6 0.1 0.0 0.4 0.6 0.0 0.1 0.0 1.1 0.2 0.5 2.5 0.5 1.0 1.5 0.2 0.9 0.8 0.8 1.8 1.0 0.1 1.2 9.1 0.3 8.9 0.1 1.3 0.0 0.0 1.4 2.3 0.0 0.2 0.4 2.0 0.0 0.9 0.6 0.0 0.1 0.7 0.2 0.0 0.4 1.5 0.4 0.2 0.0 0.1 0.2 0.1 0.1 0.9 0.5 0.6 0.0 2.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.0 2.3 2.9 1.8 1.9 1.9 1.7 1.8 1.5 1.9 2.2 2.5 6.4 4.5 28.7 2.4 1.1 0.9 1.7 1.2 32.2 2.9 2.0 8.0 4.3 2.3 11.0 39.6 1.2 4.5 3.8 0.0 0.4 2.3 1.3 3.4 2.6 5.4 0.4 38.1 0.2 0.3 2.4 3.1 1.6 1.3 7.7 2.9 6.1 2.2 40.4 40.7 3.3 0.0 4.8 1.7 1.7 3.4 3.5 1.8 7.5 5.2 3.6 1.0 32.6 21.5 0.2 2.0 4.1 2.5 1.2 2.4 1.0 2.2 5.8 0.0 1.9 2.2 7.7 3.2 1.8 1.1 0.8 4.6 4.7 4.0 1.1 SERPINB5 "maspin, PI5" ENSG00000206075 "Serpin family B member 5" P36952 18 63476958-63505085 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 216.6;skin 1: 239.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 964.1;Basal prostatic cells: 358.7;Basal respiratory cells: 272.9;Squamous epithelial cells: 535.4;Suprabasal keratinocytes: 1215.3;Urothelial cells: 564.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 124.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1279.3;HBEC3-KT: 425.6;hTCEpi: 875.0;hTERT-HME1: 217.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB009570, HPA019025, HPA019132, HPA020136" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 770000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB009570: AB_2186315, HPA019025: AB_1856726, HPA019132: AB_1856727, HPA020136: AB_1856728" "unprognostic (2.84e-3)" "unprognostic (1.05e-1)" "unprognostic (9.24e-2)" "unprognostic (1.04e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.36e-1)" "unprognostic (3.47e-3)" "prognostic unfavorable (5.71e-6)" "unprognostic (1.28e-1)" "unprognostic (1.84e-6)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (3.14e-1)" "unprognostic (8.38e-2)" 0.6 0.0 0.0 4.3 0.0 0.2 37.1 0.1 0.1 38.5 0.1 4.8 16.7 0.1 0.1 216.6 1.4 2.7 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 9.9 4.5 0.0 37.6 1.7 1.4 239.7 22.1 0.2 0.0 0.0 9.7 2.8 0.0 13.9 0.1 0.0 39.9 90.9 78.7 0.1 80.8 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 73.4 0.1 3.8 0.0 0.1 1279.3 0.0 425.6 0.0 0.0 0.0 0.0 95.8 0.2 0.0 0.0 0.6 0.1 875.0 0.0 217.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 179.9 93.4 0.1 0.0 0.2 0.0 95.1 1.4 0.0 60.2 0.3 0.0 0.3 0.2 0.2 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.2 0.9 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 964.1 358.7 272.9 224.3 0.0 5.1 27.3 0.2 0.0 90.0 3.7 0.0 0.3 0.1 14.2 0.0 0.1 9.0 6.2 0.1 5.4 3.5 0.0 0.3 0.0 0.2 5.8 12.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.3 34.6 0.0 57.6 18.6 0.6 1.8 62.2 0.0 0.0 0.0 0.0 0.0 0.1 16.3 51.7 0.0 2.5 85.4 13.5 0.1 85.4 0.0 0.0 0.0 7.1 6.6 2.2 535.4 1215.3 0.1 4.0 0.1 30.6 564.9 SGK3 "SGK2, SGKL" ENSG00000104205 "Serum/glucocorticoid regulated kinase family member 3" Q96BR1 8 66712734-66862022 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 49.0" "Cell type enhanced" "Detected in many" "Breast glandular cells: 56.0;monocytes: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 28.4" "HPA006699, HPA027146" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "HPA006699: , HPA027146: AB_1856745" "prognostic favorable (5.52e-6)" "prognostic favorable (8.28e-4)" "unprognostic (8.52e-3)" "unprognostic (1.10e-2)" "unprognostic (3.75e-1)" "unprognostic (1.37e-2)" "unprognostic (2.32e-1)" "unprognostic (1.69e-3)" "unprognostic (9.51e-2)" "unprognostic (8.86e-3)" "prognostic favorable (9.65e-4)" "unprognostic (1.94e-2)" "unprognostic (8.95e-2)" "unprognostic (4.55e-3)" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (5.29e-3)" 5.2 5.3 13.4 9.8 25.7 8.5 24.1 21.3 16.9 10.5 36.0 10.3 8.9 8.0 8.6 7.6 6.9 7.5 5.4 14.6 17.3 14.7 13.6 10.0 7.8 29.4 21.6 9.1 15.6 28.3 6.2 5.7 28.3 7.4 10.3 2.4 7.0 7.1 2.9 13.3 11.3 5.3 19.3 8.9 7.5 9.4 20.9 5.8 17.5 3.5 6.9 5.0 5.7 49.0 14.2 3.7 0.6 2.4 3.9 6.5 7.7 8.1 7.4 4.2 5.1 6.1 8.6 10.2 2.2 7.7 13.6 4.9 7.3 5.5 5.4 5.3 11.7 9.7 2.6 6.7 4.1 8.9 10.5 2.9 3.7 1.7 7.9 4.3 7.4 7.4 1.5 4.6 10.0 2.4 6.2 5.8 1.9 8.5 5.0 11.7 5.3 7.6 6.4 3.3 2.9 2.2 3.4 6.5 14.4 6.0 28.4 16.9 9.0 4.4 3.9 3.9 3.4 6.1 12.8 12.7 4.5 14.2 4.9 21.1 15.0 5.1 8.7 9.9 13.8 4.7 8.8 8.0 13.8 6.4 8.7 7.1 2.0 7.2 5.1 8.9 5.7 9.0 13.4 25.7 21.3 16.9 14.6 17.3 29.4 21.6 28.3 19.3 20.9 49.0 20.7 6.4 28.1 0.0 12.5 13.3 8.1 3.3 8.6 1.7 56.0 30.5 7.6 7.2 8.5 11.0 18.8 9.2 24.9 13.3 15.6 7.0 0.9 16.7 6.6 15.3 16.2 10.3 0.0 18.2 1.4 8.9 6.6 12.3 15.2 11.0 17.5 20.7 22.9 0.0 0.0 9.3 8.2 41.9 14.3 2.2 4.1 42.6 8.8 0.0 53.4 3.8 19.6 0.0 0.0 14.8 8.4 7.9 18.3 9.3 14.0 36.8 15.4 1.7 0.0 5.9 4.2 5.9 13.7 9.9 15.8 4.8 19.4 5.2 10.4 5.3 SH3RF1 "KIAA1494, POSH, RNF142, SH3MD2" ENSG00000154447 "SH3 domain containing ring finger 1" Q7Z6J0 4 169094259-169270956 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 146.3;Oligodendrocytes: 213.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.2;myeloid DC: 2.5;non-classical monocyte: 6.7" "Group enriched" "Detected in many" 15 "dendritic cells: 2.5;monocytes: 6.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074783 Approved Supported "Vesicles,Intermediate filaments" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "Intermediate filaments" "HPA074783: AB_2732268" "unprognostic (4.14e-1)" "unprognostic (4.67e-2)" "unprognostic (1.23e-1)" "unprognostic (7.83e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "unprognostic (1.29e-1)" "unprognostic (2.65e-1)" "unprognostic (8.44e-2)" "unprognostic (9.58e-2)" "unprognostic (4.77e-3)" "unprognostic (7.88e-2)" "prognostic favorable (5.51e-8)" "unprognostic (4.43e-2)" "unprognostic (1.63e-1)" "unprognostic (5.99e-2)" "unprognostic (1.77e-1)" 9.8 3.7 8.7 4.4 10.0 3.4 8.2 7.6 13.1 5.7 5.9 15.1 13.8 4.3 5.7 5.9 5.6 11.9 5.7 18.2 8.6 12.2 8.0 9.4 3.3 8.8 9.7 8.5 10.4 3.7 3.7 7.4 9.4 14.3 13.6 2.4 15.8 8.4 9.4 5.1 13.1 4.0 8.2 3.9 24.7 6.1 9.5 2.0 19.9 10.0 3.2 9.3 4.4 13.0 15.2 12.2 11.0 31.9 11.5 14.3 14.1 40.5 19.7 30.0 13.8 12.5 17.8 0.0 1.9 43.1 8.1 9.8 8.9 16.2 32.4 0.1 5.2 8.7 27.4 6.5 26.0 3.1 0.3 8.5 8.6 25.7 19.9 37.3 18.7 3.3 0.1 0.0 27.8 6.0 3.1 2.9 5.6 19.2 10.5 4.5 3.6 0.6 13.6 11.8 8.3 9.9 10.4 15.7 4.2 4.7 5.2 1.3 17.1 14.2 11.0 23.6 14.7 1.1 0.0 0.1 16.0 3.0 17.3 0.0 1.0 0.0 0.0 4.2 0.0 0.3 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.2 6.7 0.2 0.0 0.6 8.7 10.0 7.6 13.1 18.2 8.6 8.8 9.7 9.4 8.2 9.5 13.0 28.0 64.1 37.7 146.3 3.4 34.3 48.3 11.9 13.6 3.5 21.1 15.6 11.2 44.3 34.4 27.6 0.0 12.7 0.4 69.3 11.7 42.2 5.5 28.5 14.2 13.0 31.3 2.1 54.9 63.7 22.1 16.5 65.7 46.5 10.2 5.6 11.4 12.4 7.4 0.0 54.9 27.1 12.2 9.3 5.3 3.5 12.2 11.1 3.6 52.5 3.9 11.3 0.0 89.5 213.0 68.4 37.2 12.0 2.4 63.2 28.9 18.4 31.7 1.2 65.7 24.1 36.9 5.4 10.7 9.4 12.6 13.1 1.7 6.5 34.4 72.0 SLC15A3 "hPTR3, PHT2" ENSG00000110446 "Solute carrier family 15 member 3" Q8IY34 11 60937060-60952653 "Metabolic proteins, Predicted membrane proteins, Transporters" "Immunity, Innate immunity, Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 90.6;Kupffer cells: 59.3;Macrophages: 65.5;monocytes: 70.9;Muller glia cells: 211.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 9.0;intermediate monocyte: 12.8;memory B-cell: 4.9;myeloid DC: 6.5;neutrophil: 13.4;non-classical monocyte: 6.4;plasmacytoid DC: 10.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 23.4;BJ hTERT+ SV40 Large T+: 58.0;BJ hTERT+ SV40 Large T+ RasG12V: 74.0;HHSteC: 34.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047880, HPA057642" Approved Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA047880: AB_10959455, HPA057642: AB_2683487" "unprognostic (5.61e-2)" "prognostic favorable (4.07e-5)" "unprognostic (8.79e-2)" "unprognostic (1.67e-2)" "unprognostic (8.48e-2)" "unprognostic (9.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" "unprognostic (1.60e-1)" "unprognostic (1.46e-1)" "unprognostic (9.78e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" 27.5 12.8 11.6 30.7 10.3 35.3 18.2 10.7 15.1 19.7 13.0 34.9 12.0 13.9 3.9 9.3 18.2 19.1 27.1 9.7 13.1 14.9 15.1 52.2 40.1 14.5 10.9 29.2 6.5 4.4 8.4 27.5 13.8 16.7 9.4 17.5 10.0 8.5 6.4 7.9 28.7 15.1 13.5 63.9 18.5 5.5 14.3 12.9 10.5 10.1 15.7 15.6 17.6 15.5 4.3 0.0 2.2 0.0 12.6 9.9 23.4 1.2 21.8 58.0 74.0 0.1 1.9 9.7 0.3 8.8 14.2 1.7 0.0 0.7 3.4 9.4 0.0 0.1 0.1 0.6 34.9 0.0 0.9 6.6 0.0 15.3 0.0 0.1 2.8 0.0 0.0 0.5 3.6 0.5 0.0 1.8 9.8 0.0 0.1 3.9 0.0 3.3 0.0 1.3 0.0 0.1 2.8 9.6 0.4 0.4 4.2 5.7 0.3 0.3 1.2 1.0 0.1 0.0 0.0 3.8 3.9 0.0 13.7 0.0 9.0 1.2 0.1 12.8 0.0 4.9 0.0 0.0 6.5 1.9 0.9 0.9 13.4 0.0 6.4 10.7 0.0 2.4 11.6 10.3 10.7 15.1 9.7 13.1 14.5 10.9 13.8 13.5 14.3 15.5 19.3 9.6 13.2 0.0 7.7 1.7 0.2 4.5 2.2 1.6 0.7 1.4 2.5 1.5 3.7 0.0 0.0 3.6 9.6 1.1 0.0 0.3 7.9 0.1 2.0 12.6 0.0 0.4 0.1 2.2 15.1 5.6 1.1 0.3 15.2 3.7 20.3 3.1 90.6 5.0 0.0 1.2 2.0 59.3 35.5 3.8 8.1 65.5 1.8 4.7 70.9 211.7 1.0 0.0 0.1 2.2 2.8 4.9 2.0 0.1 0.3 0.1 3.1 5.5 13.1 3.1 3.0 4.2 0.7 0.6 1.4 2.6 1.9 4.5 1.1 0.3 SLC18A2 "SVAT, SVMT, VMAT2" ENSG00000165646 "Solute carrier family 18 member A2" Q05940 10 117241093-117279430 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Disease variant, Dystonia, FDA approved drug targets, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.1;cervix: 30.0" "Cell type enriched" "Detected in many" 5 "granulocytes: 636.0" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 11 "hypothalamus: 20.8;midbrain: 81.1;pons: 70.5" "Immune cell enriched" "Detected in some" 15 "basophil: 59.5" "Lineage enriched" "Detected in many" 15 "granulocytes: 59.5" "Cell line enriched" "Detected in some" 19 "HMC-1: 351.0" "Region enhanced" "Detected in many" "midbrain: 62.7" "Region enriched" "Detected in all" 4 "midbrain: 111.6" HPA073224 Enhanced Approved Vesicles,Centrosome NA NA "Cluster 38: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Vesicles, Centrosome" "HPA073224: AB_2732222" "unprognostic (1.49e-1)" "unprognostic (2.48e-1)" "unprognostic (2.33e-3)" "unprognostic (9.00e-2)" "unprognostic (2.85e-1)" "unprognostic (5.33e-3)" "unprognostic (2.23e-1)" "unprognostic (1.71e-2)" "unprognostic (1.40e-1)" "unprognostic (4.55e-2)" "unprognostic (2.00e-1)" "unprognostic (6.06e-3)" "unprognostic (7.94e-5)" "unprognostic (2.95e-2)" "unprognostic (2.31e-1)" "unprognostic (2.43e-1)" "unprognostic (3.57e-2)" 1.1 14.6 0.1 0.9 1.1 2.4 1.8 0.1 0.3 30.0 0.2 2.3 1.5 2.6 1.6 2.5 0.5 3.6 0.7 0.2 20.8 0.9 2.8 7.4 0.6 3.8 81.1 10.4 3.4 0.2 0.2 0.1 70.5 9.2 3.5 0.4 0.8 1.3 0.8 6.3 2.1 2.3 0.0 0.3 4.4 0.9 5.0 6.1 0.0 0.5 0.9 2.9 7.9 0.2 0.2 1.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.3 0.6 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.7 18.6 0.1 0.2 0.0 1.0 351.0 0.0 0.0 0.0 0.0 0.2 0.0 3.7 0.0 0.7 0.0 0.1 1.0 0.3 0.2 0.3 0.6 0.2 0.4 0.2 0.0 0.2 3.4 0.7 0.3 0.1 0.0 0.2 0.0 0.1 0.3 0.1 2.5 0.3 0.8 0.5 0.4 0.2 0.4 1.9 0.3 59.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.3 0.0 0.0 3.8 0.0 2.0 0.1 1.1 0.1 0.3 0.2 20.8 3.8 81.1 70.5 0.0 5.0 0.2 0.0 9.6 16.2 1.0 0.2 1.9 0.0 0.0 0.0 2.1 0.2 0.0 0.3 0.0 2.5 0.0 4.2 0.0 5.7 0.4 0.0 0.0 0.0 13.1 16.1 0.7 8.9 4.2 1.1 0.0 0.0 3.4 4.1 112.4 636.0 2.4 9.7 0.3 0.8 0.0 1.7 0.0 0.0 1.0 3.6 0.2 0.6 3.5 1.8 0.0 0.1 0.4 0.0 0.5 0.6 0.1 0.1 4.9 1.9 3.8 0.0 0.1 0.7 0.8 0.0 0.4 1.3 0.2 2.1 0.0 2.7 0.0 5.6 9.8 0.1 0.1 SLC26A11 ENSG00000181045 "Solute carrier family 26 member 11" Q86WA9 17 80219699-80253500 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 58.4;Rod photoreceptor cells: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029893 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" Nucleoplasm "HPA029893: AB_10600809" "unprognostic (5.86e-2)" "unprognostic (6.66e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (3.80e-2)" "unprognostic (2.63e-3)" "prognostic unfavorable (1.82e-6)" "unprognostic (2.05e-2)" "unprognostic (3.54e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.43e-5)" "unprognostic (2.86e-1)" "unprognostic (3.50e-1)" "unprognostic (9.54e-3)" "unprognostic (8.40e-2)" "unprognostic (8.69e-2)" "unprognostic (7.32e-2)" 12.2 36.5 27.4 8.9 24.8 16.4 11.8 14.1 23.2 16.3 21.9 12.1 7.2 11.6 8.9 7.5 13.5 7.6 7.1 21.1 45.5 19.1 10.2 18.8 14.1 27.8 33.3 22.5 10.6 11.8 35.1 9.0 30.1 16.8 4.1 11.6 11.3 9.2 5.9 13.0 11.2 6.0 17.7 22.6 10.0 4.8 42.2 3.4 24.8 3.6 5.6 11.6 12.1 17.4 0.7 12.4 14.3 11.1 7.1 5.2 16.1 6.7 8.4 15.6 9.4 13.6 2.5 0.1 13.1 7.4 11.3 4.4 8.0 5.2 6.1 15.7 14.4 0.0 17.5 13.5 18.6 0.0 2.2 9.5 8.4 7.5 3.4 1.4 13.3 2.7 6.4 16.8 9.3 11.6 0.6 0.3 6.5 3.5 11.7 0.5 1.6 5.7 14.2 13.6 5.4 16.9 6.8 17.0 18.3 22.0 20.4 0.3 9.9 11.8 6.9 10.4 0.9 17.8 7.4 1.8 6.2 0.0 10.1 0.0 1.0 0.0 0.7 0.4 1.1 0.2 1.2 1.0 0.6 0.1 1.9 0.8 0.0 0.0 0.1 0.0 1.7 0.9 27.4 24.8 14.1 23.2 21.1 45.5 27.8 33.3 30.1 17.7 42.2 17.4 8.8 6.4 13.4 22.2 3.9 4.6 8.9 5.0 5.2 27.2 9.6 9.9 2.5 5.7 5.6 12.9 58.4 14.5 5.6 3.2 1.9 7.5 0.6 7.1 7.0 12.4 10.2 2.7 13.4 6.0 8.8 8.1 3.6 11.6 1.3 15.4 8.2 2.2 15.2 3.3 17.2 3.2 8.2 11.4 10.5 0.7 17.1 15.1 3.6 12.2 4.2 22.8 5.2 12.1 13.3 3.4 3.9 12.4 2.2 9.0 7.0 6.0 4.4 40.8 32.9 6.4 7.7 0.2 5.3 2.4 4.7 26.0 8.2 16.4 2.6 5.3 SLC30A1 "ZNT1, ZRC1" ENSG00000170385 "Solute carrier family 30 member 1" Q9Y6M5 1 211571568-211579161 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 86.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 94.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015275, HPA049000" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "HPA015275: AB_1857083, HPA049000: AB_2680593" "unprognostic (1.13e-1)" "unprognostic (2.67e-3)" "unprognostic (6.94e-2)" "unprognostic (1.81e-3)" "unprognostic (3.47e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-2)" "unprognostic (1.82e-3)" "unprognostic (4.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.42e-3)" "unprognostic (4.78e-2)" "unprognostic (2.23e-2)" "unprognostic (3.03e-1)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (4.53e-2)" 14.8 18.0 15.7 10.9 17.0 29.8 8.5 15.2 19.3 18.6 27.8 15.4 28.2 10.8 9.9 8.0 12.5 12.4 10.0 16.9 15.4 20.5 86.1 7.2 6.1 17.9 17.3 7.8 11.3 10.3 4.6 10.1 16.8 7.8 13.6 6.1 9.3 7.9 1.8 16.0 19.9 11.6 16.7 15.4 9.5 13.4 18.9 4.5 16.9 4.8 7.1 12.2 7.5 13.2 10.3 15.0 7.7 9.9 32.4 14.9 70.5 27.3 19.3 13.8 13.6 6.4 46.6 5.8 24.1 24.4 19.3 17.2 11.5 15.4 16.4 15.0 9.3 4.7 28.8 14.7 18.1 15.8 10.0 22.5 37.5 17.7 28.4 20.5 8.6 3.4 18.7 25.5 17.2 9.1 3.2 9.9 24.2 10.6 12.0 10.0 3.7 20.4 42.5 26.4 7.8 13.7 26.7 13.6 62.7 14.2 7.0 20.2 14.6 10.4 24.8 35.4 22.1 11.9 19.0 4.5 9.8 15.7 9.3 1.4 1.3 0.5 0.4 1.5 0.5 0.2 0.3 0.2 0.9 0.1 0.3 0.4 0.1 0.4 1.2 0.5 0.3 0.4 15.7 17.0 15.2 19.3 16.9 15.4 17.9 17.3 16.8 16.7 18.9 13.2 29.7 9.6 9.8 3.9 8.8 28.6 8.2 3.0 16.5 11.0 24.9 14.7 21.0 18.6 4.2 36.8 6.2 11.6 19.9 54.5 1.9 6.9 44.0 37.0 19.1 27.3 9.5 26.1 0.6 12.5 32.7 15.9 8.6 66.4 5.1 7.5 17.9 94.9 32.0 6.7 0.6 22.8 2.0 27.2 14.5 6.8 9.9 25.5 21.4 3.7 18.8 29.0 1.0 1.0 0.1 9.5 41.7 7.5 8.6 13.9 49.2 29.8 6.4 9.4 6.6 15.9 11.7 37.9 17.4 24.2 46.2 24.5 14.2 14.8 23.3 13.7 SLC38A9 FLJ90709 ENSG00000177058 "Solute carrier family 38 member 9" Q8NBW4 5 55625845-55773194 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 57.8" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 182.5;Early spermatids: 262.6;Syncytiotrophoblasts: 619.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 110.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043785, HPA061702" Uncertain Supported Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA043785: AB_10961859, HPA061702: " "unprognostic (4.80e-2)" "unprognostic (1.18e-1)" "unprognostic (3.26e-2)" "prognostic unfavorable (7.24e-5)" "unprognostic (2.49e-1)" "unprognostic (8.19e-2)" "unprognostic (8.35e-2)" "unprognostic (7.95e-2)" "unprognostic (5.47e-2)" "unprognostic (9.44e-2)" "unprognostic (1.74e-1)" "unprognostic (4.87e-1)" "unprognostic (4.18e-3)" "unprognostic (1.76e-1)" "unprognostic (2.25e-1)" "unprognostic (2.84e-2)" "unprognostic (1.12e-1)" 6.1 4.8 5.4 8.8 7.3 7.1 8.2 8.1 6.3 6.5 4.1 9.4 8.1 6.6 6.6 8.4 5.0 8.3 3.8 4.3 6.6 7.4 16.6 8.0 11.2 6.3 5.9 5.4 12.1 10.7 3.3 57.8 6.6 6.1 9.8 10.0 6.4 6.0 4.4 7.6 6.6 8.5 5.5 8.4 8.1 19.2 6.3 8.8 7.7 3.8 14.5 8.4 4.8 8.9 17.9 17.3 17.1 20.0 22.0 20.4 110.0 16.5 21.3 18.3 30.4 29.5 27.2 31.6 28.6 12.7 32.1 22.5 20.2 18.2 22.8 15.4 18.4 10.8 16.4 18.7 31.1 18.9 10.8 26.3 21.0 20.2 25.7 13.7 20.0 21.3 20.9 18.6 16.5 15.0 23.6 16.4 29.4 7.2 15.6 17.6 28.6 32.2 24.7 14.0 8.1 14.5 17.3 9.3 25.4 24.0 20.1 34.4 29.6 3.6 11.7 26.8 16.6 20.5 47.6 20.8 10.9 17.4 11.4 3.3 9.3 5.5 5.2 8.7 7.5 7.4 4.5 6.1 8.4 4.2 6.2 5.3 2.0 7.7 6.9 8.0 5.9 4.9 5.4 7.3 8.1 6.3 4.3 6.6 6.3 5.9 6.6 5.5 6.3 8.9 7.3 6.4 3.1 21.9 14.2 3.2 4.2 8.5 2.8 6.6 5.7 3.9 2.8 11.5 9.8 9.2 8.4 182.5 10.4 8.9 1.9 8.9 262.6 4.4 9.2 8.1 4.2 8.4 56.2 11.4 71.5 7.2 8.6 7.3 2.5 8.0 10.4 22.1 26.3 1.7 57.3 4.3 8.2 10.0 8.0 82.4 7.5 11.7 5.4 38.4 11.0 5.6 4.1 55.8 103.2 10.9 9.7 4.9 8.4 4.6 4.4 7.2 6.3 7.4 6.6 3.3 7.0 15.8 6.5 8.1 3.4 619.9 8.7 4.0 5.2 4.7 SLC48A1 "FLJ20489, hHRG-1, HRG1" ENSG00000211584 "Solute carrier family 48 member 1" Q6P1K1 12 47753916-47782751 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 135.6" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 102.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065396, HPA073994" Approved Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "HPA065396: , HPA073994: " "unprognostic (9.60e-2)" "prognostic favorable (4.27e-4)" "unprognostic (1.13e-2)" "unprognostic (1.18e-2)" "unprognostic (1.22e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (9.39e-5)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (9.88e-2)" "unprognostic (1.54e-2)" "unprognostic (6.63e-3)" "prognostic favorable (1.34e-6)" "unprognostic (1.45e-1)" "unprognostic (5.96e-2)" "unprognostic (1.52e-1)" "unprognostic (2.72e-2)" 27.5 37.4 98.8 6.9 131.6 12.3 27.6 116.7 104.3 26.8 58.5 26.8 7.4 20.2 16.2 28.9 28.4 15.4 29.0 96.2 99.8 44.1 15.2 22.3 7.0 125.5 127.0 53.1 19.5 29.4 17.7 17.7 113.4 20.4 10.6 11.2 20.2 22.7 29.9 22.0 14.3 16.6 103.2 25.8 22.1 9.9 126.8 7.9 52.6 21.5 8.2 27.6 22.6 135.6 11.9 36.3 5.7 42.8 36.4 15.5 12.3 8.3 18.3 7.8 8.0 11.7 31.0 7.2 102.7 23.3 15.5 45.4 7.3 9.6 6.0 59.1 6.8 49.4 30.4 16.1 20.8 13.3 27.9 9.2 19.3 11.2 13.6 40.6 22.1 20.0 13.1 28.3 5.1 24.7 6.5 13.7 3.9 21.9 17.1 6.0 1.6 39.0 31.5 31.3 7.3 3.3 11.0 13.8 7.8 10.2 46.0 12.2 12.3 10.9 14.3 21.1 6.0 21.6 14.3 2.2 14.2 62.8 6.7 0.1 17.9 12.4 5.2 13.5 4.7 10.4 6.4 5.5 12.9 9.9 7.7 6.4 36.7 2.0 7.7 2.6 5.5 6.3 98.8 131.6 116.7 104.3 96.2 99.8 125.5 127.0 113.4 103.2 126.8 135.6 35.2 9.6 13.5 35.3 6.2 6.6 9.7 6.4 22.2 11.1 15.5 15.2 16.4 20.0 5.5 51.5 2.1 9.5 2.3 9.0 23.5 10.4 8.5 10.9 6.2 22.3 8.4 53.0 9.1 9.8 2.3 15.6 4.6 18.0 1.3 16.4 16.8 11.8 24.1 15.2 8.3 13.5 6.1 18.0 9.9 12.5 32.6 14.1 5.4 8.4 28.4 26.8 2.1 11.1 100.3 6.6 5.2 23.0 10.1 12.9 9.2 34.9 2.3 11.2 6.6 11.9 11.6 4.1 10.5 20.9 11.9 3.6 3.3 18.0 7.5 11.6 SLC49A4 "DIRC2, FLJ14784, RCC4" ENSG00000138463 "Solute carrier family 49 member 4" Q96SL1 3 122795069-122881139 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 44.0;Extravillous trophoblasts: 61.2;Syncytiotrophoblasts: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072579 Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA072579: AB_2686536" "unprognostic (1.40e-1)" "unprognostic (8.53e-3)" "unprognostic (1.20e-1)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (5.36e-2)" "prognostic unfavorable (7.48e-4)" "unprognostic (9.74e-2)" "unprognostic (2.58e-1)" "unprognostic (3.95e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.87e-1)" "prognostic favorable (8.81e-11)" "unprognostic (2.36e-1)" "unprognostic (2.64e-1)" "unprognostic (1.73e-1)" "unprognostic (7.13e-2)" 4.4 5.0 4.9 2.7 5.1 5.9 3.1 4.9 5.3 3.0 6.2 4.1 1.9 2.6 3.8 5.6 3.1 3.7 6.4 5.7 5.9 4.6 3.5 5.2 2.0 4.8 5.6 2.2 6.5 12.7 2.4 7.6 5.6 4.9 4.5 5.7 3.7 3.6 15.9 6.6 2.6 2.7 5.2 2.8 3.1 2.5 5.6 1.9 5.2 14.0 2.5 4.0 2.6 5.9 7.4 6.1 5.9 3.3 7.5 6.1 19.6 3.1 6.7 4.9 5.0 14.4 8.0 1.0 3.9 3.5 10.9 10.5 4.3 5.6 4.7 1.6 3.2 1.2 3.3 6.2 5.5 0.7 0.7 5.0 15.0 3.5 5.9 7.6 5.6 2.0 0.7 1.3 6.3 3.3 0.9 0.8 5.3 2.5 9.8 2.0 13.3 1.5 7.0 8.4 6.1 4.6 9.1 4.1 8.4 3.7 4.8 1.6 8.0 7.6 2.8 4.6 2.6 1.3 1.2 0.4 3.8 1.3 4.2 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.9 0.0 0.2 0.0 0.0 0.0 4.9 5.1 4.9 5.3 5.7 5.9 4.8 5.6 5.6 5.2 5.6 5.9 3.5 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 44.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 61.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 226.6 0.4 0.0 0.0 0.0 SLC66A1 "FLJ20320, LAAT-1, LAAT1, PQLC2" ENSG00000040487 "Solute carrier family 66 member 1" Q6ZP29 1 19312326-19329300 "Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Cytotrophoblasts: 26.9;Extravillous trophoblasts: 17.0;Hofbauer cells: 37.4;Syncytiotrophoblasts: 60.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057810 Approved Supported Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA057810: AB_2683535" "unprognostic (7.84e-3)" "unprognostic (6.56e-2)" "unprognostic (6.54e-2)" "prognostic favorable (3.50e-4)" "unprognostic (3.77e-3)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.64e-5)" "unprognostic (2.61e-1)" "unprognostic (4.47e-2)" "unprognostic (1.04e-1)" "unprognostic (1.42e-3)" "unprognostic (3.82e-2)" "unprognostic (4.70e-3)" "unprognostic (8.64e-2)" "unprognostic (2.07e-1)" "unprognostic (6.56e-2)" "unprognostic (4.46e-2)" 10.7 24.8 12.4 5.6 13.8 13.1 10.7 17.9 14.7 12.9 11.3 11.6 10.7 10.8 9.1 9.8 10.1 6.9 11.3 12.5 13.0 15.2 26.6 10.7 7.9 15.7 13.6 11.0 17.4 7.9 23.2 7.1 14.7 14.2 4.7 12.1 10.5 6.3 14.2 14.1 16.7 5.7 12.1 14.6 14.5 18.6 14.2 4.3 13.5 6.1 5.6 9.9 10.6 15.1 14.6 15.0 13.9 22.4 13.3 12.4 17.6 18.0 24.6 24.7 20.7 22.1 18.0 4.7 23.0 13.3 34.2 10.6 13.7 16.2 11.1 9.9 16.5 3.6 13.4 24.0 37.8 3.1 6.3 20.6 16.7 34.9 11.1 13.8 9.6 8.1 26.8 10.7 24.0 12.8 2.1 10.2 13.3 5.2 13.3 8.1 17.5 8.2 18.9 9.4 17.2 14.3 13.5 9.1 35.5 12.4 15.1 35.8 12.8 20.4 11.8 35.0 16.1 18.4 13.8 2.7 25.1 18.3 17.3 1.3 10.5 10.3 3.7 9.1 2.6 6.0 3.9 3.1 13.7 5.4 1.1 2.3 6.4 4.1 13.8 20.5 3.8 4.5 12.4 13.8 17.9 14.7 12.5 13.0 15.7 13.6 14.7 12.1 14.2 15.1 2.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 26.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 17.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 60.5 0.1 0.0 0.0 0.0 SLC6A4 "5-HTT, HTT, OCD1, SERT1" ENSG00000108576 "Solute carrier family 6 member 4" P31645 17 30194319-30236002 "FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 232.0" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 125.4;Proximal enterocytes: 100.9;Syncytiotrophoblasts: 106.4" "Cancer enhanced" "Detected in some" "breast cancer: 2.3" "Group enriched" "Detected in some" 11 "midbrain: 232.0;pons: 86.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.9;CACO-2: 3.9;Hep G2: 10.4" "Region enriched" "Detected in some" 4 "midbrain: 58.4" "Group enriched" "Detected in some" 7 "midbrain: 38.9;pons: 29.1" "HPA054723, HPA071354, HPA074728" Supported Supported Supported "Golgi apparatus,Vesicles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus, Vesicles" "HPA054723: , HPA071354: , HPA074728: AB_2686708" "unprognostic (7.45e-2)" "unprognostic (7.13e-2)" "unprognostic (2.26e-1)" "unprognostic (3.72e-4)" "unprognostic (2.07e-1)" "unprognostic (8.42e-3)" "unprognostic (2.73e-2)" "unprognostic (3.39e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-3)" "unprognostic (2.70e-3)" "unprognostic (1.16e-1)" "unprognostic (8.78e-2)" "unprognostic (4.98e-2)" "unprognostic (1.76e-1)" "unprognostic (4.05e-2)" "unprognostic (7.18e-2)" 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.3 0.2 0.2 0.0 0.5 10.3 0.0 0.0 2.8 1.7 0.0 0.9 0.1 0.2 0.2 0.0 28.8 0.1 14.8 232.0 0.1 1.4 0.2 0.0 18.4 86.1 0.1 0.1 0.1 0.7 0.2 0.1 0.5 40.3 0.0 0.0 0.1 0.9 0.3 0.2 0.0 0.5 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 10.4 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.4 0.5 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.2 0.1 0.2 14.8 232.0 86.1 0.0 0.2 0.2 1.1 16.0 5.0 0.3 0.0 0.1 0.4 0.1 17.1 1.2 0.1 0.0 1.0 0.0 1.9 1.8 0.0 125.4 1.5 0.2 0.0 0.0 2.8 0.2 0.6 3.2 0.0 0.0 0.9 0.0 8.6 1.3 0.0 0.5 2.5 0.2 2.2 0.3 9.5 0.0 0.6 2.3 0.0 1.0 1.2 2.2 0.3 5.9 0.0 0.0 0.1 0.5 2.1 0.5 0.5 0.4 0.0 0.4 0.1 0.3 100.9 0.4 0.7 0.8 0.0 1.3 0.5 0.5 0.9 4.8 0.3 106.4 0.5 0.2 4.1 0.3 SLC7A14 "KIAA1613, PPP1R142" ENSG00000013293 "Solute carrier family 7 member 14" Q8TBB6 3 170459548-170586075 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 15.9;pituitary gland: 7.3;retina: 6.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 28.4;Excitatory neurons: 61.9;Horizontal cells: 28.6;Inhibitory neurons: 90.2;Oligodendrocytes: 67.4" "Group enriched" "Detected in some" 11 "glioma: 0.8;pancreatic cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 3.2;SCLC-21H: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045929 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "Nucleoplasm, Plasma membrane" "HPA045929: AB_2679501" "unprognostic (1.00e-1)" "unprognostic (9.56e-2)" "unprognostic (1.03e-1)" "unprognostic (4.15e-2)" "unprognostic (1.43e-2)" "unprognostic (7.46e-2)" "unprognostic (9.16e-2)" "unprognostic (1.13e-1)" "unprognostic (1.29e-1)" "unprognostic (6.68e-3)" "unprognostic (6.36e-2)" "unprognostic (3.03e-6)" "unprognostic (1.54e-2)" "unprognostic (8.05e-2)" "unprognostic (1.71e-2)" "unprognostic (3.24e-3)" 0.0 2.3 8.9 0.4 8.1 0.1 0.0 5.5 8.8 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 7.9 15.9 0.1 0.0 0.0 0.0 15.6 6.4 0.1 0.7 0.0 7.3 0.0 14.9 0.1 0.4 6.1 0.0 0.0 0.1 0.1 0.3 0.1 4.0 0.0 0.2 0.1 8.9 0.0 0.0 0.0 0.0 0.0 0.1 7.7 0.0 0.0 0.1 0.0 0.5 0.9 0.0 0.3 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.9 8.1 5.5 8.8 7.9 15.9 15.6 6.4 14.9 4.0 8.9 7.7 0.8 3.2 2.2 4.6 0.1 0.4 0.3 0.1 0.0 28.4 0.1 0.0 1.0 0.0 2.5 0.0 2.1 0.1 0.1 0.0 0.0 0.0 0.6 0.2 0.2 0.5 1.8 0.0 61.9 0.0 0.1 0.4 0.0 0.1 2.5 0.1 0.4 0.9 0.0 28.6 90.2 0.1 0.0 0.0 1.2 0.6 2.1 0.4 3.6 6.5 0.0 1.8 0.0 9.5 67.4 0.1 1.2 2.6 0.1 0.3 0.1 0.2 3.0 4.3 0.0 0.7 0.5 0.0 0.2 0.0 0.6 0.0 0.4 0.1 0.0 0.2 SLC9A6 "KIAA0267, NHE6" ENSG00000198689 "Solute carrier family 9 member A6" Q92581 X 135973841-136047269 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.3;Horizontal cells: 48.8;Inhibitory neurons: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059445, HPA059590" Enhanced Supported Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 18: U-2197 - ECM organization" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA059445: AB_2684021, HPA059590: AB_2684075" "unprognostic (1.35e-1)" "unprognostic (8.28e-3)" "unprognostic (4.36e-1)" "unprognostic (4.93e-2)" "unprognostic (1.84e-1)" "unprognostic (1.19e-1)" "unprognostic (2.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.15e-1)" "unprognostic (2.72e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (7.07e-2)" "unprognostic (5.30e-2)" "unprognostic (1.75e-1)" "unprognostic (4.49e-2)" "unprognostic (5.06e-2)" 5.1 6.3 11.6 5.6 11.9 4.6 3.3 1.2 15.7 5.6 0.0 6.0 8.5 6.4 3.3 6.3 5.7 5.5 8.6 12.7 19.0 6.9 4.5 6.7 5.7 7.8 4.4 8.0 3.8 10.4 2.2 4.7 8.9 4.0 6.1 14.4 4.1 4.9 7.5 4.7 7.8 7.4 3.4 5.7 5.8 5.8 15.3 5.6 6.7 7.1 6.6 5.6 1.6 4.2 20.0 10.5 9.1 3.8 14.8 14.2 17.3 15.9 16.9 13.3 27.9 9.2 15.5 14.8 35.2 18.4 19.8 11.6 14.3 14.0 19.1 11.7 12.9 4.0 15.3 5.3 7.9 11.6 13.3 7.7 11.6 22.0 10.8 9.4 11.2 12.5 7.5 20.5 14.9 8.7 15.5 3.4 6.0 7.1 14.0 10.4 16.0 15.2 9.4 9.8 9.5 7.2 11.4 1.2 8.9 8.8 4.5 8.7 16.4 16.5 10.9 24.5 20.7 9.6 23.8 12.7 10.0 19.4 9.4 2.0 5.0 3.0 6.4 7.0 11.1 4.1 7.1 5.9 5.8 2.6 7.6 5.7 2.0 5.1 6.0 3.5 6.9 5.4 11.6 11.9 1.2 15.7 12.7 19.0 7.8 4.4 8.9 3.4 15.3 4.2 4.3 3.2 5.4 22.9 5.9 7.5 1.4 6.2 7.4 14.2 2.7 3.4 11.2 12.8 4.0 12.9 8.4 2.5 6.1 8.9 0.0 4.3 0.8 4.2 4.1 4.9 10.7 5.0 40.3 6.0 2.4 5.1 8.6 6.8 1.3 4.6 8.2 9.6 9.9 48.8 42.0 4.0 8.2 13.0 7.0 1.4 5.6 9.8 8.8 15.9 8.2 12.9 4.1 19.6 22.7 6.1 6.0 4.5 3.8 2.0 10.3 6.0 3.1 7.8 0.0 5.1 8.4 9.0 11.9 7.0 6.8 2.9 8.9 3.1 6.0 3.1 SLC9A7 NHE7 ENSG00000065923 "Solute carrier family 9 member A7" Q96T83 X 46599251-46759118 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Potassium transport, Sodium transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 41.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 43.3;Inhibitory neurons: 66.8;Oligodendrocyte precursor cells: 69.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048938, HPA075385" Approved Supported Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA048938: AB_2680565, HPA075385: AB_2686747" "unprognostic (2.77e-1)" "unprognostic (4.68e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (8.58e-4)" "prognostic unfavorable (8.14e-4)" "unprognostic (2.16e-2)" "unprognostic (2.73e-3)" "unprognostic (5.26e-3)" "unprognostic (1.28e-2)" "unprognostic (9.25e-2)" "unprognostic (5.30e-2)" "unprognostic (1.11e-1)" "unprognostic (2.08e-1)" "unprognostic (7.20e-2)" "unprognostic (2.62e-1)" "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" 0.5 5.0 9.1 2.4 41.6 3.6 5.8 6.3 14.6 1.2 0.5 0.6 1.2 0.8 2.6 1.9 1.7 1.6 1.1 8.6 17.0 2.6 3.1 1.3 6.3 13.9 7.5 4.3 3.4 8.9 9.2 1.1 14.2 4.6 0.9 4.9 6.0 2.0 5.7 2.1 2.2 0.7 6.7 3.7 6.3 0.8 14.5 3.2 4.3 2.5 6.3 1.8 1.3 5.1 10.4 7.7 1.1 3.3 1.2 7.4 4.3 9.6 12.0 5.7 4.5 7.9 10.9 22.7 2.9 15.6 11.0 4.6 7.4 10.9 10.3 11.9 3.9 2.3 3.1 3.3 4.6 1.0 17.9 4.6 1.4 16.1 10.6 26.8 8.2 7.7 0.2 0.3 7.9 15.7 2.6 1.2 5.3 5.0 9.2 10.0 0.4 0.2 4.4 11.4 8.2 1.0 4.9 7.3 2.1 9.2 9.7 0.4 0.4 12.0 4.0 1.8 5.7 2.3 0.5 11.2 17.1 0.1 4.0 0.5 0.2 0.1 0.1 0.2 0.1 1.7 0.2 0.1 1.1 1.7 0.1 0.1 0.8 0.5 0.2 2.8 0.3 0.2 9.1 41.6 6.3 14.6 8.6 17.0 13.9 7.5 14.2 6.7 14.5 5.1 0.5 3.2 8.2 11.4 21.0 0.6 10.1 0.9 1.2 13.0 16.9 8.6 5.7 1.5 2.6 16.5 4.2 7.9 24.4 0.3 0.0 17.6 0.0 1.8 2.0 1.5 2.4 5.5 43.3 14.2 0.7 2.7 13.3 1.7 0.0 4.5 0.7 6.5 6.4 13.5 66.8 2.0 0.0 6.3 8.4 0.6 0.9 9.2 1.8 3.7 8.0 6.1 1.0 69.9 1.6 16.4 0.1 0.4 2.8 21.0 0.1 2.1 0.1 3.5 6.6 12.1 1.9 0.0 1.6 4.2 1.0 7.3 2.9 1.3 0.9 11.5 SNX11 ENSG00000002919 "Sorting nexin 11" Q9Y5W9 17 48103357-48123601 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044787, HPA054660" Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Endoplasmic reticulum" Vesicles "HPA044787: AB_10795988, HPA054660: AB_2682560" "unprognostic (1.75e-1)" "unprognostic (6.86e-3)" "unprognostic (4.34e-2)" "unprognostic (4.33e-3)" "unprognostic (2.45e-1)" "unprognostic (1.54e-1)" "unprognostic (2.68e-3)" "unprognostic (2.07e-1)" "unprognostic (9.27e-2)" "unprognostic (2.15e-1)" "unprognostic (5.42e-2)" "unprognostic (2.12e-1)" "unprognostic (5.22e-3)" "unprognostic (9.02e-3)" "unprognostic (2.70e-2)" "unprognostic (9.50e-2)" "unprognostic (3.89e-2)" 14.3 12.0 18.0 18.1 19.1 21.5 11.1 18.2 19.4 10.5 16.4 13.8 8.7 10.5 12.5 19.9 9.6 8.9 12.5 18.3 18.4 15.8 14.5 11.4 21.7 20.1 18.9 8.8 11.7 13.4 10.7 11.3 18.8 12.1 12.5 11.9 12.2 8.7 12.8 11.6 12.4 17.0 20.1 24.0 12.4 11.4 19.8 16.1 20.0 15.3 29.1 13.3 11.6 20.7 20.6 25.4 21.9 21.1 18.1 8.3 22.8 21.8 13.9 26.5 28.8 36.0 17.7 21.6 27.3 24.1 15.5 18.6 21.2 21.0 29.2 52.4 24.5 32.5 17.5 17.5 18.4 36.0 22.7 13.8 20.8 25.1 23.7 16.5 22.4 20.4 19.8 21.7 17.4 17.0 21.8 22.8 12.2 23.6 21.3 13.5 39.7 24.8 16.1 20.1 15.7 28.6 14.2 9.7 37.7 26.6 20.1 25.4 18.8 30.6 18.2 20.3 26.3 34.0 54.1 26.0 22.1 16.4 19.6 28.7 34.6 35.6 19.0 43.3 13.1 22.1 10.5 12.9 28.2 21.2 8.6 14.7 92.9 16.8 54.5 12.9 10.1 24.0 18.0 19.1 18.2 19.4 18.3 18.4 20.1 18.9 18.8 20.1 19.8 20.7 8.7 6.4 2.0 2.9 15.4 6.0 5.0 5.9 7.4 8.9 6.4 6.2 5.3 1.5 4.3 16.5 2.1 11.7 14.2 13.3 5.9 11.4 1.9 6.2 4.6 8.0 14.9 3.6 4.1 15.3 12.2 6.0 6.6 7.1 2.5 5.4 6.1 6.9 19.9 15.2 3.9 9.0 6.1 23.2 4.6 2.1 5.3 15.9 5.4 2.8 37.5 14.2 14.4 5.0 8.8 18.1 5.6 6.8 6.3 6.9 9.9 9.9 2.9 9.3 13.1 4.6 8.8 10.3 21.2 8.9 5.1 16.4 7.5 7.7 8.0 6.4 SNX14 RGS-PX2 ENSG00000135317 "Sorting nexin 14" Q9Y5W7 6 85505496-85594156 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Disease variant, Mental retardation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017639 Approved Supported Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Vesicles, Cytosol" "HPA017639: AB_1857345" "unprognostic (1.16e-2)" "unprognostic (3.29e-2)" "unprognostic (2.19e-2)" "unprognostic (1.52e-2)" "unprognostic (5.23e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (1.92e-2)" "unprognostic (3.45e-2)" "unprognostic (4.60e-1)" "unprognostic (1.57e-2)" "unprognostic (3.14e-2)" "unprognostic (2.37e-2)" "unprognostic (1.10e-3)" "unprognostic (1.02e-1)" "unprognostic (1.38e-1)" "unprognostic (1.87e-3)" "unprognostic (4.72e-3)" 27.3 39.9 39.0 23.0 40.5 31.4 41.7 44.4 61.0 30.8 49.7 39.7 29.8 23.5 57.3 24.3 28.2 28.3 24.8 40.7 47.0 54.4 69.6 39.6 32.6 40.1 40.7 26.8 43.6 47.1 36.3 36.2 43.1 33.2 35.1 47.2 27.8 30.8 16.4 28.6 31.7 22.4 40.9 37.4 45.3 87.0 42.5 18.9 40.5 12.9 28.8 35.1 24.7 44.2 46.1 27.3 44.5 64.9 98.3 71.6 46.0 58.0 78.5 44.2 67.5 49.0 75.4 60.3 69.8 74.4 85.9 60.7 30.5 58.8 69.4 53.3 18.0 66.1 36.4 75.1 80.9 62.4 65.0 63.0 43.7 52.0 51.6 81.1 79.4 23.2 67.7 50.4 96.9 52.1 4.4 117.0 18.3 72.1 31.1 26.2 90.6 29.1 107.1 82.7 19.8 44.5 35.0 76.6 56.3 57.9 47.9 108.9 71.6 35.4 21.8 44.1 60.3 50.4 87.0 22.8 71.3 72.2 71.8 36.7 21.5 33.0 19.9 33.6 14.7 13.3 13.4 18.1 26.2 14.7 12.0 15.0 9.9 22.9 40.9 7.9 16.7 15.7 39.0 40.5 44.4 61.0 40.7 47.0 40.1 40.7 43.1 40.9 42.5 44.2 28.5 93.0 47.2 76.4 25.3 14.7 18.7 32.8 15.9 36.4 23.3 15.1 16.9 15.7 39.1 22.0 56.3 50.4 32.6 30.7 5.9 31.7 87.1 37.3 22.2 26.9 31.8 13.2 115.2 41.6 31.9 23.1 37.8 32.5 31.6 36.0 26.0 28.7 35.4 15.2 124.4 26.1 65.1 37.7 22.3 21.6 19.6 33.4 28.4 63.7 43.1 26.1 41.2 85.5 91.0 34.4 22.0 29.3 23.8 15.7 31.9 25.1 58.9 40.7 19.7 26.2 33.0 173.0 14.9 15.9 14.8 56.5 26.4 26.5 28.6 17.7 SNX15 ENSG00000110025 "Sorting nexin 15" Q9NRS6 11 65027439-65040572 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal enterocytes: 5.6;Enteroendocrine cells: 7.8;granulocytes: 8.2;monocytes: 7.9;Paneth cells: 8.0;Proximal enterocytes: 6.5;Undifferentiated cells: 5.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038955 Approved Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Cytosol" "Vesicles, Plasma membrane" "HPA038955: AB_10672834" "unprognostic (2.00e-2)" "unprognostic (4.90e-2)" "unprognostic (3.93e-1)" "unprognostic (9.61e-4)" "unprognostic (2.79e-1)" "unprognostic (4.06e-3)" "unprognostic (4.45e-3)" "unprognostic (4.74e-2)" "unprognostic (1.09e-1)" "unprognostic (9.55e-2)" "unprognostic (8.93e-3)" "unprognostic (1.79e-2)" "unprognostic (8.84e-2)" "unprognostic (7.86e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.68e-4)" 17.1 13.3 17.3 10.2 18.5 10.5 15.3 19.4 19.2 16.6 9.0 22.5 15.3 15.8 6.4 14.9 12.9 7.4 15.0 18.4 17.1 17.0 10.1 11.9 9.3 19.3 18.2 14.8 12.7 10.7 9.4 7.3 16.1 12.9 8.8 5.8 12.3 10.9 25.7 17.5 16.8 8.9 16.1 10.8 16.4 5.3 17.8 9.4 10.6 15.5 7.4 18.0 14.9 18.5 31.1 22.3 14.7 14.2 17.3 12.4 7.9 10.0 13.6 23.3 21.3 17.6 23.7 30.7 16.7 17.4 29.3 16.8 16.8 15.2 9.8 47.0 14.0 15.8 18.2 30.2 18.3 10.7 24.5 10.6 22.2 24.7 14.5 13.0 14.1 22.6 27.0 19.6 12.5 18.8 29.2 36.8 15.5 12.0 21.9 23.7 8.4 34.0 17.6 6.7 25.6 19.2 25.3 23.0 23.2 9.7 23.4 18.6 27.5 23.5 22.9 24.1 14.7 20.9 38.3 30.3 23.2 14.5 8.4 9.2 13.6 13.6 7.6 16.2 6.2 8.9 7.8 6.8 9.4 8.7 5.6 5.1 2.1 4.3 23.6 6.4 8.3 7.3 17.3 18.5 19.4 19.2 18.4 17.1 19.3 18.2 16.1 16.1 17.8 18.5 0.3 0.0 3.3 0.0 0.8 1.0 0.1 0.4 4.0 0.0 0.5 0.3 0.4 0.0 0.2 0.0 0.0 0.4 0.1 5.6 0.0 4.8 0.0 0.1 0.2 0.9 7.8 1.3 0.0 3.1 0.6 0.4 1.1 0.1 8.2 0.4 0.7 0.1 1.0 0.0 0.0 3.3 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 7.9 0.2 0.0 0.0 0.0 3.9 8.0 0.4 1.1 0.0 6.5 0.6 0.7 0.4 0.0 0.7 1.0 0.0 0.0 1.5 0.4 0.4 1.1 0.2 5.6 0.1 SNX16 ENSG00000104497 "Sorting nexin 16" P57768 8 81799581-81842866 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 82.8;Late spermatids: 137.3;Spermatocytes: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024730, HPA024731, HPA024817" Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA024730: AB_10600220, HPA024731: AB_1857346, HPA024817: AB_10602313" "unprognostic (5.50e-2)" "unprognostic (3.20e-2)" "unprognostic (1.40e-1)" "unprognostic (8.41e-3)" "unprognostic (3.21e-3)" "unprognostic (7.54e-3)" "unprognostic (1.24e-3)" "unprognostic (1.33e-1)" "unprognostic (2.12e-1)" "unprognostic (2.18e-1)" "unprognostic (3.94e-2)" "unprognostic (1.43e-1)" "unprognostic (5.73e-3)" "unprognostic (7.60e-3)" "unprognostic (2.30e-1)" "unprognostic (1.35e-1)" "unprognostic (3.65e-1)" 10.1 5.2 4.7 6.0 5.7 10.7 8.2 6.6 7.6 8.6 2.5 6.3 6.4 9.7 8.3 17.3 6.2 10.8 8.1 5.3 6.6 6.6 5.5 6.7 5.1 6.1 7.4 9.6 3.1 8.9 3.7 5.5 8.6 7.3 6.6 4.9 5.7 7.7 4.6 11.2 5.7 11.9 5.8 12.0 9.0 14.9 5.7 9.4 8.7 9.4 6.7 7.0 7.7 6.7 13.8 3.8 6.6 6.3 22.9 13.7 7.3 16.6 20.2 14.1 20.6 3.4 11.1 2.2 10.0 11.4 16.5 11.0 5.1 6.8 19.5 19.9 3.1 7.1 5.2 6.2 17.4 2.9 11.5 10.5 10.6 5.4 12.5 15.8 10.0 7.8 4.5 26.0 32.9 7.2 15.6 5.1 2.8 12.6 6.2 6.6 9.5 2.4 12.7 6.7 10.9 8.3 3.1 3.9 8.3 9.8 10.3 5.5 7.7 19.5 15.6 13.5 7.2 15.1 12.5 5.7 8.4 9.1 15.7 9.2 4.5 6.1 2.1 2.8 2.0 1.6 2.5 1.7 4.0 4.4 2.9 2.8 6.2 2.6 2.4 3.0 5.0 1.9 4.7 5.7 6.6 7.6 5.3 6.6 6.1 7.4 8.6 5.8 5.7 6.7 10.6 6.4 9.4 9.8 6.4 25.2 12.1 5.0 9.6 5.5 12.1 7.6 8.8 7.2 9.3 5.5 4.2 2.3 3.7 7.5 5.9 5.9 82.8 9.4 7.8 11.5 3.0 8.2 24.7 6.0 4.0 8.5 10.7 16.2 8.2 5.0 13.9 3.5 5.7 55.5 18.4 6.2 8.2 7.0 10.0 137.3 23.3 7.2 3.6 8.4 2.3 4.3 1.0 23.1 22.2 6.7 5.5 16.1 8.6 12.6 3.7 7.3 10.9 5.2 19.7 12.1 9.3 74.2 26.5 13.0 32.0 9.9 5.4 4.2 4.7 20.7 SNX25 SBBI31 ENSG00000109762 "Sorting nexin 25" Q9H3E2 4 185204237-185370185 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 128.9;Astrocytes: 50.6;Excitatory neurons: 57.7;Inhibitory neurons: 60.7;Oligodendrocyte precursor cells: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "HDLM-2: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036928 Supported Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA036928: AB_10669720" "unprognostic (9.20e-2)" "unprognostic (1.31e-1)" "unprognostic (2.26e-1)" "unprognostic (4.29e-3)" "unprognostic (8.89e-2)" "unprognostic (5.63e-2)" "unprognostic (1.43e-2)" "unprognostic (6.41e-2)" "unprognostic (5.35e-2)" "unprognostic (2.99e-2)" "unprognostic (4.03e-3)" "unprognostic (1.87e-1)" "unprognostic (3.33e-1)" "unprognostic (1.13e-1)" "unprognostic (1.57e-1)" "unprognostic (1.32e-2)" "unprognostic (8.55e-3)" 7.6 8.0 7.0 7.3 8.4 2.0 9.5 17.3 7.9 6.0 23.9 12.3 3.5 6.9 6.3 7.1 9.7 8.5 8.7 7.5 8.9 11.3 9.1 29.1 11.5 9.6 10.0 7.4 10.0 13.3 10.5 11.8 9.7 14.9 6.7 25.5 6.7 8.6 10.2 6.2 7.9 7.0 8.1 9.5 6.2 12.7 8.8 2.9 16.7 8.6 12.9 7.2 5.4 7.3 11.9 6.2 7.8 11.0 20.5 15.0 11.5 35.6 17.1 17.9 14.9 5.3 8.1 33.6 3.8 26.0 12.4 4.6 8.9 7.8 20.0 55.9 14.5 5.7 7.5 12.8 11.9 3.8 8.0 10.4 8.3 15.6 8.6 36.0 15.7 6.3 12.0 33.3 23.9 3.5 1.5 6.9 6.3 1.6 5.9 4.9 9.0 8.6 43.0 4.5 16.5 11.9 7.4 2.0 30.3 10.8 4.2 4.9 30.0 10.2 6.5 9.8 15.7 29.3 12.8 7.1 16.7 2.8 12.9 0.0 0.0 0.0 0.1 0.0 0.3 0.7 0.3 0.4 0.0 1.0 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.0 7.0 8.4 17.3 7.9 7.5 8.9 9.6 10.0 9.7 8.1 8.8 7.3 9.5 25.6 128.9 50.6 12.6 4.8 4.2 2.3 4.6 15.9 7.0 3.4 6.8 0.0 7.3 5.5 31.3 4.8 5.5 5.4 0.0 4.8 5.9 11.5 8.1 9.6 0.0 0.0 57.7 2.6 4.9 4.9 5.1 10.3 1.3 3.9 12.5 8.8 2.0 6.7 60.7 4.0 2.0 3.2 2.5 4.8 9.6 2.2 21.4 32.8 0.6 5.6 3.1 55.3 21.4 3.9 1.6 9.8 11.3 9.4 5.6 2.3 6.7 15.7 0.0 4.8 5.7 9.0 16.2 2.3 6.1 5.6 7.0 10.3 3.3 5.5 SNX5 ENSG00000089006 "Sorting nexin 5" Q9Y5X3 20 17941597-17968980 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 271.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 639.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020679, HPA051187, HPA076450" Approved Supported Vesicles,Cytosol NA NA 8200 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB020679: , HPA051187: AB_2681379, HPA076450: " "unprognostic (6.00e-2)" "unprognostic (2.35e-1)" "unprognostic (3.08e-2)" "unprognostic (4.00e-2)" "unprognostic (4.47e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (2.30e-10)" "unprognostic (1.67e-1)" "unprognostic (6.19e-2)" "unprognostic (1.69e-1)" "unprognostic (2.62e-2)" "unprognostic (1.56e-1)" "unprognostic (1.77e-1)" "unprognostic (3.15e-2)" "unprognostic (6.50e-2)" "unprognostic (3.48e-2)" "unprognostic (2.99e-1)" 42.4 51.4 12.5 43.7 15.2 57.5 37.6 14.9 12.4 35.7 14.5 37.6 47.1 28.3 49.4 35.2 33.5 24.9 28.5 11.0 13.5 59.3 33.7 36.1 59.1 15.5 13.6 51.4 32.0 24.8 21.7 28.9 16.8 23.6 40.1 14.2 34.3 17.2 70.8 28.7 40.2 24.4 17.2 57.5 33.1 15.5 14.0 21.2 70.2 21.8 51.2 34.7 32.5 21.2 103.0 108.6 45.3 49.6 29.6 49.8 270.7 84.1 43.3 49.9 55.9 104.8 140.2 169.6 48.6 49.9 69.7 112.2 63.8 124.6 67.2 44.1 57.8 150.1 49.5 639.4 48.0 106.6 173.9 49.2 54.2 54.6 98.3 37.1 72.8 111.3 72.8 109.6 58.6 79.6 94.2 92.6 48.4 87.0 55.3 110.0 115.2 126.1 61.2 116.4 45.0 26.4 76.0 113.7 102.1 34.0 62.4 67.8 57.3 77.8 98.7 49.2 101.5 77.8 129.2 137.2 38.5 37.6 69.6 69.6 58.7 83.6 54.8 81.7 50.0 80.6 49.6 54.6 71.9 75.2 29.7 42.7 4.8 39.0 92.3 37.2 67.3 54.9 12.5 15.2 14.9 12.4 11.0 13.5 15.5 13.6 16.8 17.2 14.0 21.2 35.6 64.1 113.1 21.5 93.0 31.7 45.7 49.0 48.3 19.1 48.9 44.2 38.5 38.6 59.8 49.7 27.1 101.0 54.9 59.6 160.4 47.8 43.6 51.1 42.3 48.7 31.7 98.4 18.8 44.8 137.7 57.7 52.0 66.9 130.8 47.9 139.9 41.4 151.9 16.8 19.9 54.4 34.6 174.6 47.2 16.0 60.9 88.2 26.6 31.9 68.4 66.3 55.6 24.6 20.3 37.2 58.3 51.6 96.7 49.2 100.0 271.5 52.0 19.8 19.7 50.7 39.6 19.1 44.6 83.5 32.4 78.5 53.0 66.5 100.1 57.4 SNX8 Mvp1 ENSG00000106266 "Sorting nexin 8" Q9Y5X2 7 2251770-2354318 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 108.9;Late spermatids: 358.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 100.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057296, HPA060194" Approved Supported Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA057296: AB_2683401, HPA060194: AB_2684219" "unprognostic (2.22e-2)" "unprognostic (3.38e-1)" "unprognostic (9.85e-3)" "unprognostic (1.39e-1)" "unprognostic (2.08e-2)" "unprognostic (9.32e-2)" "prognostic unfavorable (8.47e-6)" "unprognostic (5.23e-2)" "unprognostic (1.91e-3)" "unprognostic (1.54e-2)" "unprognostic (3.06e-1)" "unprognostic (6.01e-2)" "unprognostic (1.54e-1)" "unprognostic (5.10e-2)" "unprognostic (4.83e-2)" "unprognostic (1.12e-2)" "unprognostic (1.35e-1)" 15.4 6.8 13.7 11.3 14.1 10.9 12.4 11.8 11.4 7.0 10.9 7.7 10.6 6.9 3.1 10.2 7.0 9.8 12.8 12.9 11.3 7.3 7.2 9.7 21.5 15.1 13.0 7.5 7.5 5.9 5.4 9.3 13.3 4.3 6.8 5.7 7.8 3.0 11.0 10.2 9.5 5.6 12.9 32.7 6.9 23.2 15.1 7.9 8.3 7.5 17.7 8.5 5.7 14.9 40.3 38.7 15.6 21.8 21.3 20.5 36.7 19.2 28.4 31.8 39.2 27.3 30.6 23.4 7.7 22.8 100.9 10.6 13.6 10.5 16.1 5.9 12.8 13.0 15.5 22.9 53.9 12.7 20.8 41.4 12.1 39.0 15.0 8.5 12.1 18.3 26.0 26.9 26.4 26.4 4.3 13.5 28.4 22.4 19.0 20.6 32.2 10.7 7.5 18.8 7.5 19.7 17.4 47.8 27.3 17.0 35.5 27.4 18.5 26.6 69.7 44.0 25.4 17.5 22.9 21.9 26.4 16.9 73.6 11.8 15.4 5.1 2.9 17.2 2.1 26.1 2.1 2.9 21.8 30.6 2.0 2.4 2.6 2.2 17.8 5.4 3.4 8.7 13.7 14.1 11.8 11.4 12.9 11.3 15.1 13.0 13.3 12.9 15.1 14.9 7.4 6.4 9.4 3.9 35.7 5.2 7.8 6.1 2.8 10.0 12.3 10.4 12.4 10.0 4.8 3.7 8.4 16.7 7.7 10.5 13.7 21.0 108.9 3.3 12.8 13.0 6.0 26.3 5.0 30.0 15.4 10.3 10.7 4.5 12.6 8.2 45.3 8.8 78.1 21.9 7.8 10.9 6.1 35.2 75.2 358.9 12.2 36.7 14.2 6.5 41.9 7.8 7.2 2.5 9.1 26.9 7.9 13.2 12.9 8.8 12.5 14.9 5.5 12.5 0.0 5.3 9.6 10.6 22.9 5.7 6.1 43.4 6.3 29.6 9.7 9.2 SORCS2 KIAA1329 ENSG00000184985 "Sortilin related VPS10 domain containing receptor 2" Q96PQ0 4 7192538-7742836 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.9" "Cell type enhanced" "Detected in many" "Astrocytes: 107.1;Bipolar cells: 70.3;Excitatory neurons: 41.4;Muller glia cells: 33.0;Oligodendrocytes: 76.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 7.6;HaCaT: 19.6;HMC-1: 14.5;RPMI-8226: 9.1;SiHa: 14.1;THP-1: 8.4;U-937: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071818 Approved Vesicles,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Cytosol" "HPA071818: " "unprognostic (1.38e-1)" "unprognostic (6.32e-2)" "unprognostic (1.91e-2)" "unprognostic (4.37e-2)" "unprognostic (4.91e-3)" "unprognostic (1.82e-2)" "unprognostic (4.60e-2)" "unprognostic (1.14e-2)" "unprognostic (1.49e-3)" "prognostic unfavorable (3.55e-4)" "unprognostic (1.52e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.17e-3)" "unprognostic (5.37e-2)" "unprognostic (2.09e-1)" "unprognostic (7.27e-3)" 2.4 1.1 13.4 3.4 18.3 1.7 1.6 11.6 15.9 8.5 0.0 4.5 1.4 4.7 3.8 2.2 3.3 3.6 2.0 12.1 11.3 9.0 4.6 4.4 0.8 18.6 17.6 5.8 0.7 0.0 2.7 0.2 14.7 5.2 1.1 12.9 1.0 2.4 1.1 1.8 2.6 6.2 11.3 0.4 1.6 1.6 14.1 3.1 3.1 1.2 1.2 3.0 3.7 22.9 0.8 1.1 1.3 0.2 0.1 0.0 0.0 0.2 0.1 1.6 0.4 0.2 0.6 0.0 7.6 5.0 1.3 19.6 0.0 0.0 0.3 0.0 0.0 0.0 2.8 0.3 0.2 0.0 14.5 0.2 4.3 6.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.4 0.0 0.9 0.0 1.6 9.1 0.2 0.0 0.8 0.7 14.1 0.0 0.0 0.8 0.0 8.4 0.0 4.9 1.4 0.0 0.1 0.0 0.0 0.0 1.6 8.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 18.3 11.6 15.9 12.1 11.3 18.6 17.6 14.7 11.3 14.1 22.9 0.1 3.2 11.3 107.1 0.0 0.1 0.3 4.6 0.0 70.3 0.1 2.4 2.0 0.0 6.9 5.5 0.0 0.0 0.3 0.0 0.0 0.2 2.2 0.4 0.4 0.3 0.0 0.0 41.4 0.0 0.0 5.0 0.0 0.9 0.0 5.4 0.4 1.6 0.2 1.7 24.3 0.0 2.0 0.3 0.0 11.6 12.8 0.4 1.8 8.4 0.1 33.0 1.0 8.0 76.2 1.1 0.0 7.9 0.1 0.4 0.4 1.4 2.0 2.7 0.0 0.9 1.0 0.1 0.3 0.0 0.4 0.0 0.3 1.5 0.0 0.6 SPESP1 SP-ESP ENSG00000258484 "Sperm equatorial segment protein 1" Q6UW49 15 68818221-68946811 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 73.2" "Group enriched" "Detected in many" 4 "Early spermatids: 400.4;Spermatocytes: 455.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 17.8;BJ hTERT+ SV40 Large T+ RasG12V: 18.6;HBF TERT88: 21.7;HMC-1: 13.4;OE19: 15.9;RPTEC TERT1: 26.8;SCLC-21H: 19.9;WM-115: 31.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA045936, HPA051040" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted in male reproductive system" NA NA 52000 "Cluster 46: Basophils - DNA binding" "Cluster 83: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "HPA045936: AB_2679504, HPA051040: AB_2681322" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (9.82e-2)" "unprognostic (1.59e-1)" "unprognostic (1.42e-2)" "unprognostic (1.06e-1)" "unprognostic (5.96e-2)" "unprognostic (2.79e-1)" "unprognostic (2.40e-1)" "unprognostic (8.99e-2)" "unprognostic (1.10e-2)" "unprognostic (1.16e-2)" "unprognostic (2.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (9.67e-2)" 2.3 3.4 1.1 0.8 1.1 0.4 2.2 1.2 1.6 1.2 1.0 1.6 1.2 1.5 6.3 2.6 1.8 3.5 3.1 1.1 1.2 2.0 1.2 1.1 0.8 1.3 1.2 3.4 1.9 4.7 1.2 12.9 1.3 3.5 1.1 2.8 1.8 2.9 1.6 1.0 0.9 1.2 1.3 1.3 1.5 73.2 1.1 0.9 1.9 1.9 0.7 2.4 0.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 17.8 18.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 21.7 5.0 0.0 0.0 0.0 0.0 6.3 0.0 13.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 2.9 0.0 0.0 3.3 15.9 0.0 0.0 1.4 0.0 26.8 0.2 19.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 31.6 1.1 1.3 0.4 0.2 1.1 0.5 0.5 0.4 0.3 0.8 0.3 0.3 0.5 0.5 0.2 0.8 0.4 0.4 0.5 1.1 1.1 1.2 1.6 1.1 1.2 1.3 1.2 1.3 1.3 1.1 1.6 5.1 0.0 0.0 0.0 0.2 1.9 3.0 23.7 1.8 1.0 2.7 4.1 4.1 1.5 4.0 7.3 4.2 92.3 0.3 0.2 1.9 2.1 400.4 3.9 3.4 3.6 1.8 0.8 0.0 2.7 7.2 5.5 0.0 2.0 0.0 1.7 2.2 1.8 7.8 0.0 0.0 0.9 6.1 2.1 3.3 90.3 21.1 1.2 5.4 0.0 1.0 5.3 0.0 0.0 0.0 0.9 0.0 8.6 0.0 3.3 0.0 3.9 6.3 5.6 46.0 3.4 4.2 455.0 88.7 1.1 2.3 62.1 0.5 11.1 0.2 1.5 SPG21 "ABHD21, ACP33, BM-019, GL010, MAST" ENSG00000090487 "SPG21 abhydrolase domain containing, maspardin" Q9NZD8 15 64963022-64990310 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 181.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040407, HPA040436" Approved Supported Vesicles,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA040407: AB_2676965, HPA040436: AB_10796454" "unprognostic (7.47e-2)" "unprognostic (2.94e-2)" "unprognostic (5.81e-2)" "unprognostic (2.98e-1)" "unprognostic (1.64e-1)" "unprognostic (5.40e-3)" "unprognostic (7.25e-2)" "unprognostic (1.43e-1)" "unprognostic (4.19e-2)" "unprognostic (8.07e-2)" "unprognostic (4.24e-3)" "unprognostic (1.15e-1)" "unprognostic (3.96e-1)" "unprognostic (1.55e-1)" "unprognostic (3.49e-1)" "unprognostic (2.57e-1)" "unprognostic (3.19e-1)" 56.6 61.7 48.4 50.8 54.1 69.4 68.8 51.5 52.9 60.4 66.0 61.6 52.1 60.2 150.1 46.1 73.4 54.7 54.4 47.8 50.3 85.3 113.1 61.9 56.9 52.1 50.2 55.3 54.7 72.1 47.1 66.3 52.7 49.8 59.3 38.6 45.7 59.0 74.3 58.5 46.6 64.5 51.1 52.6 60.1 35.0 52.6 57.7 83.1 42.4 58.8 61.2 47.8 59.4 87.0 127.0 62.8 119.5 158.7 155.7 78.0 52.8 179.7 103.2 119.8 57.4 131.1 99.1 80.6 124.8 153.1 113.3 182.1 124.5 97.8 41.0 58.5 85.7 81.7 104.0 200.7 82.2 72.7 107.0 139.3 82.1 154.2 100.7 125.6 112.2 72.7 78.3 127.8 124.1 75.8 71.5 69.6 193.9 66.3 78.2 67.3 174.6 107.1 103.6 76.7 68.6 62.7 131.4 124.9 123.3 89.9 140.9 61.5 87.1 90.6 125.4 80.6 55.6 101.8 58.2 112.8 215.1 75.1 9.9 138.2 15.5 14.1 84.2 13.1 39.0 13.8 14.7 76.9 37.6 19.9 10.9 181.4 15.7 69.8 25.1 17.5 52.3 48.4 54.1 51.5 52.9 47.8 50.3 52.1 50.2 52.7 51.1 52.6 59.4 29.4 9.6 56.3 11.1 67.7 74.9 81.8 70.6 66.6 16.2 62.7 39.4 32.1 61.5 51.5 71.7 37.5 202.9 33.6 42.7 137.0 97.1 6.0 32.9 36.9 56.9 64.8 54.3 13.1 74.1 92.2 67.5 46.9 34.3 28.5 37.5 38.2 121.6 153.9 20.2 13.7 58.2 61.1 158.7 145.4 13.2 86.6 128.5 80.0 16.9 123.2 24.8 64.9 5.5 19.6 62.3 93.5 89.9 66.2 145.2 121.1 202.3 57.9 18.9 39.5 93.4 39.5 35.4 51.3 75.4 82.8 186.5 46.5 35.5 69.5 123.5 SPPL2A "IMP3, PSL2" ENSG00000138600 "Signal peptide peptidase like 2A" Q8TCT8 15 50702266-50765709 "Enzymes, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036062, HPA067304" Enhanced Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA036062: AB_10611670, HPA067304: AB_2685820" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (5.82e-3)" "unprognostic (3.71e-1)" "unprognostic (1.70e-1)" "unprognostic (2.15e-1)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (6.36e-2)" "unprognostic (2.04e-2)" "unprognostic (4.00e-2)" "unprognostic (3.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-2)" "unprognostic (6.96e-2)" "unprognostic (3.66e-1)" 41.1 34.7 8.3 57.6 10.9 54.5 32.0 11.1 8.5 36.6 48.6 93.4 79.6 27.9 21.5 26.5 26.8 39.4 37.1 6.8 12.3 57.9 107.0 43.4 40.2 15.3 12.8 13.6 63.7 158.5 13.0 54.1 12.5 29.5 82.8 12.5 44.5 32.6 109.3 25.2 67.6 41.0 11.2 37.3 41.7 18.5 12.1 39.5 35.2 81.8 41.7 51.7 20.9 14.5 57.3 96.9 37.0 49.2 142.3 84.3 58.2 89.1 149.1 80.5 114.1 113.1 64.3 35.1 65.0 176.3 120.7 83.5 45.2 54.3 89.5 72.2 27.5 67.0 61.5 58.9 117.4 42.0 104.5 73.9 98.3 66.8 106.7 59.4 80.2 37.7 51.3 134.2 107.6 131.5 20.1 16.2 15.8 90.8 22.0 24.2 57.3 77.6 109.7 130.4 29.7 33.4 54.0 102.7 63.4 74.0 73.2 81.6 98.9 128.7 51.7 83.7 106.7 54.0 100.2 38.8 58.1 69.4 90.3 48.7 52.3 48.9 27.9 48.6 17.4 18.3 22.3 25.5 37.4 19.2 12.4 20.5 37.7 23.5 56.6 33.1 30.4 50.2 8.3 10.9 11.1 8.5 6.8 12.3 15.3 12.8 12.5 11.2 12.1 14.5 66.2 48.1 35.9 20.5 51.9 43.1 79.1 76.3 37.5 14.8 36.4 21.3 77.5 52.9 44.3 68.0 20.9 136.5 72.7 215.5 23.5 87.1 18.8 107.2 56.6 59.6 38.4 30.3 32.0 167.1 88.3 74.3 52.0 57.3 45.7 20.5 46.8 124.1 85.9 8.4 31.4 86.5 36.7 68.7 55.7 7.0 44.7 83.0 32.0 23.4 134.5 27.5 64.9 25.6 26.2 131.9 127.3 36.5 49.9 92.2 143.0 46.8 41.8 17.2 26.3 88.0 51.6 31.7 15.3 39.3 38.8 204.5 60.6 30.8 76.0 94.1 SPPL3 "DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4" ENSG00000157837 "Signal peptide peptidase like 3" Q8TCT6 12 120762510-120904358 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004194, HPA059958" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Plasma membrane" "HPA004194: AB_2667171, HPA059958: AB_2684179" "unprognostic (3.29e-1)" "unprognostic (2.29e-2)" "unprognostic (3.39e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-1)" "unprognostic (7.96e-3)" "prognostic unfavorable (1.29e-5)" "unprognostic (3.17e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.48e-1)" "unprognostic (2.44e-1)" "unprognostic (2.66e-1)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (7.54e-2)" "unprognostic (9.40e-2)" 20.9 14.9 25.3 11.9 28.1 20.9 24.2 29.0 27.5 30.0 13.1 26.7 18.2 26.3 15.7 44.3 28.6 18.7 18.1 25.4 30.6 22.8 19.3 20.4 15.9 25.0 26.0 31.4 21.3 49.6 13.9 28.4 26.1 20.6 27.2 15.5 20.2 27.0 15.7 56.5 18.8 29.6 24.1 24.3 15.2 39.0 26.4 32.7 31.2 19.6 27.8 28.6 34.2 31.4 30.0 29.2 43.4 27.4 56.2 37.7 30.5 22.5 66.6 47.4 37.9 30.5 29.9 27.4 0.1 39.4 42.0 35.6 44.8 48.4 48.9 21.9 27.5 23.6 16.2 23.4 59.2 27.4 29.3 38.1 75.9 40.7 38.1 56.0 47.1 41.5 26.5 13.4 41.2 26.3 36.7 22.0 29.2 27.8 20.6 21.6 36.6 19.7 36.8 83.8 29.7 31.9 42.8 19.6 34.7 46.1 58.9 18.7 35.4 21.9 29.5 13.6 17.1 30.9 60.3 26.4 32.5 22.3 36.9 4.8 1.2 1.1 1.3 1.2 1.8 1.3 1.6 1.7 2.1 1.6 1.5 1.7 2.2 1.3 1.1 2.7 1.4 0.7 25.3 28.1 29.0 27.5 25.4 30.6 25.0 26.0 26.1 24.1 26.4 31.4 35.2 19.2 20.8 79.3 25.3 55.1 32.3 29.4 43.3 37.8 35.2 24.1 21.2 20.0 19.8 40.5 27.1 42.0 21.2 47.2 1.9 19.3 8.6 20.9 26.9 33.0 27.1 14.5 97.2 24.7 29.0 33.2 25.0 29.7 4.5 68.7 37.5 33.1 38.3 37.0 112.6 33.7 22.4 38.1 39.3 8.0 28.6 34.5 26.6 79.6 26.6 23.0 16.5 141.3 192.3 22.8 34.9 35.0 22.0 33.4 34.0 18.1 18.1 22.4 13.1 32.3 27.4 55.6 41.1 76.9 84.7 64.6 22.4 35.0 35.4 37.6 SREBF2 "bHLHd2, SREBP2" ENSG00000198911 "Sterol regulatory element binding transcription factor 2" Q12772 22 41833079-41907307 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031962, HPA031963" Approved Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 27: Brain & Skin - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "HPA031962: AB_10601266, HPA031963: AB_2674090" "unprognostic (6.53e-2)" "unprognostic (6.07e-2)" "unprognostic (1.75e-2)" "unprognostic (1.50e-3)" "unprognostic (3.41e-3)" "unprognostic (9.08e-2)" "unprognostic (5.04e-2)" "unprognostic (1.31e-1)" "unprognostic (4.78e-1)" "unprognostic (1.04e-2)" "unprognostic (2.30e-1)" "unprognostic (9.85e-2)" "prognostic favorable (1.37e-4)" "unprognostic (4.68e-2)" "unprognostic (1.92e-2)" "unprognostic (3.22e-1)" "unprognostic (7.93e-3)" 22.8 80.7 50.1 31.1 58.7 32.3 24.5 22.3 60.5 26.5 2.5 47.1 40.8 34.4 60.5 82.0 27.4 25.3 53.8 51.8 32.3 33.3 36.2 43.2 35.2 38.5 37.8 35.8 45.8 51.4 30.5 24.5 38.3 33.5 31.6 21.0 49.1 22.9 34.1 58.4 35.9 30.1 16.1 26.1 53.8 20.4 37.8 25.0 23.3 33.5 36.2 29.7 39.0 45.1 65.5 45.8 119.4 111.6 68.4 90.9 66.7 21.4 71.1 24.8 50.5 54.3 84.2 115.8 29.7 52.6 91.1 109.6 68.7 141.8 17.5 32.9 75.0 58.0 79.7 54.6 113.8 85.7 37.9 85.8 78.7 65.1 80.6 56.7 49.2 64.2 60.6 135.9 26.4 83.1 62.5 64.5 75.7 81.2 34.9 71.3 68.1 189.0 103.3 67.6 48.2 36.3 49.1 89.3 91.7 69.5 56.3 150.2 53.0 33.2 61.0 15.9 25.8 98.3 54.3 91.7 32.4 64.0 51.9 0.0 4.7 1.6 4.6 3.6 3.1 7.0 2.5 3.3 5.0 4.8 2.2 2.6 0.7 1.4 3.1 6.3 1.5 4.8 50.1 58.7 22.3 60.5 51.8 32.3 38.5 37.8 38.3 16.1 37.8 45.1 14.5 44.8 43.3 100.6 35.4 16.3 13.5 52.2 30.7 41.0 36.3 23.1 30.3 37.1 38.0 58.8 10.4 25.4 23.5 67.0 3.9 20.3 15.9 25.2 10.5 16.8 49.1 14.1 72.6 44.3 22.6 16.3 42.8 59.2 12.7 43.2 8.2 34.3 14.8 57.2 75.1 39.4 52.9 10.3 14.8 7.0 31.4 16.3 7.2 67.5 18.1 18.6 20.6 90.5 129.5 38.4 30.5 27.4 29.2 27.9 26.3 4.8 30.0 18.7 19.7 13.7 20.5 8.4 13.8 55.7 28.1 36.5 19.0 43.0 40.3 30.2 STAM STAM1 ENSG00000136738 "Signal transducing adaptor molecule" Q92783 10 17644151-17716824 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 53.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 76.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034399, HPA043882" Supported Supported Vesicles NA NA 82000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 24: Non-specific - Transcription regulation" Vesicles "CAB034399: AB_2197486, HPA043882: AB_2678713" "unprognostic (1.09e-2)" "unprognostic (8.32e-2)" "unprognostic (1.10e-1)" "unprognostic (3.95e-2)" "unprognostic (9.11e-3)" "unprognostic (1.04e-1)" "prognostic unfavorable (3.44e-6)" "unprognostic (1.39e-1)" "unprognostic (8.53e-2)" "unprognostic (8.58e-2)" "unprognostic (1.37e-2)" "unprognostic (8.39e-2)" "unprognostic (1.02e-3)" "unprognostic (1.39e-1)" "unprognostic (2.26e-1)" "unprognostic (1.87e-1)" "unprognostic (2.02e-1)" 10.8 13.3 7.7 6.9 9.7 53.1 8.9 14.0 11.8 10.7 3.4 8.0 8.2 9.0 5.8 12.2 7.8 9.1 18.0 9.2 8.7 10.2 6.9 10.9 7.5 9.8 9.5 11.4 10.4 10.3 7.4 8.5 9.8 8.7 7.7 11.2 8.5 6.1 24.5 10.0 7.3 8.5 9.6 6.8 11.4 8.1 9.1 13.1 10.8 10.1 7.5 10.9 9.0 14.7 34.8 19.8 30.8 14.2 30.1 21.9 10.3 45.1 19.8 41.0 33.1 25.9 31.7 9.1 7.2 33.9 31.7 18.2 27.6 21.1 35.0 10.9 12.7 86.3 15.3 43.1 31.8 6.5 43.7 22.7 27.0 33.6 28.3 26.6 19.8 56.3 30.1 10.5 43.8 10.4 35.7 5.6 14.7 19.7 10.2 18.0 29.0 11.9 17.5 11.2 13.0 19.2 24.6 16.7 34.6 24.1 27.5 9.4 26.6 23.9 24.5 42.7 21.1 6.6 11.5 15.6 25.6 9.6 15.6 47.5 7.5 12.5 5.9 8.2 5.6 5.4 12.8 6.2 9.6 3.1 8.8 7.1 5.9 17.3 7.5 5.5 76.5 6.4 7.7 9.7 14.0 11.8 9.2 8.7 9.8 9.5 9.8 9.6 9.1 14.7 13.2 12.8 23.4 15.7 14.1 22.9 5.3 16.2 23.9 19.7 9.4 8.9 30.0 5.7 14.0 16.5 10.4 10.2 24.3 6.4 5.9 15.1 3.5 16.3 22.3 11.0 11.4 56.8 31.7 13.4 10.5 23.5 15.8 25.9 31.6 13.0 10.4 7.8 15.5 10.1 36.9 7.8 2.0 10.4 16.3 3.5 9.6 15.6 19.6 39.4 8.4 13.7 10.3 31.7 59.4 29.9 8.0 6.0 20.8 10.1 5.7 15.6 14.0 14.5 26.3 22.3 12.6 22.1 14.6 21.8 21.0 24.6 27.6 18.4 8.1 8.5 STAM2 Hbp ENSG00000115145 "Signal transducing adaptor molecule 2" O75886 2 152116801-152175763 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 16.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035528, HPA035529" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "Nucleoplasm, Cytosol" "HPA035528: AB_10601606, HPA035529: AB_10672868" "unprognostic (1.53e-1)" "unprognostic (1.79e-1)" "unprognostic (4.81e-2)" "unprognostic (1.73e-1)" "unprognostic (2.31e-1)" "unprognostic (5.16e-2)" "unprognostic (2.76e-2)" "unprognostic (3.15e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-1)" "unprognostic (1.22e-1)" "unprognostic (7.92e-2)" "unprognostic (1.11e-2)" "unprognostic (1.28e-1)" "unprognostic (1.76e-1)" "unprognostic (2.82e-1)" "unprognostic (1.03e-2)" 9.7 9.9 7.3 7.9 8.3 3.1 12.5 7.5 8.9 10.9 8.0 10.3 9.3 10.9 8.7 9.1 12.8 9.3 9.6 6.3 7.7 14.6 11.0 10.8 8.7 7.5 7.9 11.0 8.8 12.8 6.5 10.3 7.9 12.9 10.9 11.1 11.9 8.9 5.8 10.8 9.3 10.1 8.0 8.3 11.7 12.6 7.4 8.5 14.3 7.7 8.9 10.7 6.6 9.7 8.3 7.9 7.2 8.8 18.5 22.0 7.7 16.8 19.4 10.7 13.6 7.8 7.8 10.8 13.1 24.2 9.4 8.3 8.0 15.6 17.1 13.3 6.3 7.8 5.1 11.8 21.2 11.5 14.6 16.9 14.6 20.0 26.8 15.5 11.7 7.2 5.1 7.5 22.2 8.1 6.1 8.9 4.5 6.1 11.2 4.9 8.9 5.9 16.7 14.1 3.8 5.9 9.3 8.2 14.1 8.0 11.1 10.5 15.3 23.7 7.6 18.8 10.3 6.1 6.7 6.8 17.9 9.2 13.2 16.8 3.4 4.6 1.7 4.6 1.6 1.7 1.8 1.9 2.7 2.0 1.5 1.9 8.6 2.6 7.1 3.2 2.2 1.6 7.3 8.3 7.5 8.9 6.3 7.7 7.5 7.9 7.9 8.0 7.4 9.7 17.6 25.6 33.5 39.2 10.9 13.8 12.0 16.4 15.9 10.6 17.9 11.6 30.5 7.2 28.9 16.5 16.7 7.4 14.7 22.1 23.5 13.9 147.8 37.2 25.5 15.1 8.3 13.5 43.8 14.2 14.6 22.7 27.0 22.2 27.1 14.8 17.5 16.0 16.7 1.7 39.7 20.2 20.3 20.0 13.0 64.4 15.8 16.9 14.2 32.8 19.6 14.7 8.2 51.8 61.0 21.2 18.2 15.4 10.9 14.3 13.9 14.8 55.6 11.6 26.3 18.0 16.1 54.1 20.1 13.5 13.2 20.2 9.3 18.2 13.5 16.1 STARD3 "es64, MLN64" ENSG00000131748 "StAR related lipid transfer domain containing 3" Q14849 17 39637090-39664201 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "SK-BR-3: 260.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017021, HPA024307, HPA073948" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "CAB017021: , HPA024307: , HPA073948: " "unprognostic (1.11e-1)" "unprognostic (2.14e-2)" "unprognostic (6.35e-2)" "unprognostic (8.92e-3)" "unprognostic (2.09e-2)" "unprognostic (2.94e-1)" "prognostic unfavorable (3.60e-5)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (6.25e-3)" "unprognostic (5.88e-2)" "prognostic unfavorable (7.70e-4)" "unprognostic (1.33e-1)" "unprognostic (5.22e-2)" "unprognostic (8.51e-3)" "unprognostic (3.00e-2)" 24.8 33.4 18.3 18.8 29.1 25.4 23.4 21.6 18.9 22.3 14.9 21.5 24.1 20.4 2.7 24.1 21.5 17.2 16.3 17.9 15.4 18.9 25.8 28.8 22.3 21.1 21.3 21.3 26.5 15.2 24.0 17.1 19.0 20.1 5.2 3.2 21.2 11.3 23.9 27.0 26.7 9.2 18.7 33.1 26.5 26.2 22.5 14.8 21.4 9.5 8.8 21.0 20.1 18.5 29.3 47.6 18.6 33.5 19.9 22.9 31.2 23.1 24.9 27.1 24.3 24.0 47.6 25.2 47.7 17.8 30.8 55.4 11.3 21.0 6.3 36.2 34.5 15.2 18.8 30.1 25.9 29.6 35.5 24.5 19.0 29.8 12.6 19.0 23.4 36.4 41.0 27.4 23.5 24.7 32.2 25.6 22.2 15.3 20.6 28.5 31.4 40.1 15.0 35.7 24.9 29.1 16.1 260.8 64.0 10.8 34.1 41.7 26.3 43.2 29.5 46.5 43.6 27.5 37.8 18.7 36.2 36.8 45.1 23.7 36.3 54.4 42.7 35.5 30.7 20.8 29.6 32.7 38.3 26.1 29.1 27.8 63.6 39.6 29.3 18.7 38.5 33.8 18.3 29.1 21.6 18.9 17.9 15.4 21.1 21.3 19.0 18.7 22.5 18.5 45.8 3.2 7.5 31.0 23.2 16.6 13.0 23.4 14.2 12.6 19.9 14.6 3.4 18.6 14.8 11.0 37.5 28.5 32.9 21.0 9.8 26.5 2.7 9.7 11.7 35.8 27.5 11.1 17.3 35.4 37.2 16.2 29.6 11.0 19.0 22.2 45.0 11.9 49.8 18.5 14.8 11.6 14.2 49.0 18.5 5.3 17.1 27.7 5.4 9.4 18.5 15.8 29.9 12.1 30.2 35.9 22.9 13.2 24.3 20.2 41.5 10.3 8.3 13.2 13.1 21.8 14.4 9.3 16.2 15.9 16.9 40.0 35.2 18.6 15.1 20.1 STARD3NL "MENTHO, MGC3251" ENSG00000010270 "STARD3 N-terminal like" O95772 7 38178245-38230670 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019204 Enhanced Supported Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA019204: AB_2197800" "unprognostic (1.55e-3)" "unprognostic (2.80e-3)" "unprognostic (2.22e-1)" "unprognostic (2.58e-1)" "unprognostic (4.37e-2)" "prognostic unfavorable (2.20e-4)" "prognostic unfavorable (1.44e-5)" "unprognostic (9.64e-2)" "unprognostic (1.89e-1)" "unprognostic (5.37e-2)" "prognostic favorable (8.48e-4)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (2.41e-2)" "unprognostic (8.09e-3)" "unprognostic (2.65e-1)" "unprognostic (8.71e-2)" 26.8 21.8 35.5 23.1 37.6 37.8 22.0 39.6 41.7 31.4 29.8 21.5 18.5 32.6 27.1 12.3 27.5 22.0 27.1 35.7 44.1 34.0 17.4 32.8 21.3 42.0 46.8 24.2 16.4 17.9 25.5 49.4 48.4 40.6 23.5 26.3 14.9 21.6 17.3 6.6 20.3 33.1 40.5 27.1 17.6 32.7 41.8 22.3 32.7 17.5 15.3 29.4 14.8 42.9 40.9 42.7 92.6 60.4 62.8 62.2 32.4 65.2 67.2 63.2 82.4 34.3 63.0 31.9 64.0 59.9 192.0 42.9 51.4 49.5 95.2 29.0 45.1 64.8 22.1 47.4 55.3 71.5 72.7 58.8 24.0 67.0 53.0 72.0 116.7 86.1 75.0 53.7 98.4 25.1 40.9 115.2 65.5 33.7 33.9 49.6 85.9 14.9 89.0 37.5 36.9 86.7 22.4 58.8 64.1 127.0 40.9 93.8 80.0 43.0 61.0 67.8 93.5 57.4 62.2 12.1 87.0 125.6 142.4 33.5 46.8 56.2 52.2 43.3 23.9 30.8 21.6 39.3 42.3 28.4 18.1 35.6 53.1 71.8 47.0 30.3 24.8 47.1 35.5 37.6 39.6 41.7 35.7 44.1 42.0 46.8 48.4 40.5 41.8 42.9 45.8 19.2 47.3 15.0 33.2 20.8 57.3 43.4 20.5 8.7 26.8 15.0 18.2 14.3 25.9 31.3 12.5 48.3 67.2 15.5 31.3 31.4 125.3 37.0 42.5 45.5 21.5 28.2 21.9 34.3 91.2 34.2 19.9 33.1 23.5 36.0 51.0 12.4 65.8 5.0 24.5 20.9 32.6 63.2 77.9 115.2 18.3 56.8 26.6 17.8 24.2 34.6 114.4 27.6 26.0 34.0 21.6 25.9 34.3 55.2 19.4 50.1 22.8 13.0 13.1 23.4 38.4 48.8 37.3 12.2 16.2 42.3 47.5 24.5 19.5 46.4 STEAP2 "IPCA-1, PCANAP1, STAMP1, STMP" ENSG00000157214 "STEAP2 metalloreductase" Q8NFT2 7 90167590-90238137 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "prostate: 127.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 68.0;Inhibitory neurons: 53.0;Prostatic glandular cells: 102.9" "Cancer enriched" "Detected in many" 12 "prostate cancer: 88.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 22.5;CAPAN-2: 48.1;U-138 MG: 27.4" "Low region specificity" "Detected in all" "HPA029115, HPA055603" Uncertain Supported Vesicles NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA029115: AB_10603894, HPA055603: " "unprognostic (6.26e-3)" "unprognostic (2.48e-1)" "unprognostic (2.55e-1)" "unprognostic (1.65e-1)" "unprognostic (8.20e-4)" "unprognostic (2.34e-1)" "unprognostic (1.13e-1)" "unprognostic (3.67e-3)" "unprognostic (7.91e-2)" "unprognostic (1.70e-1)" "unprognostic (9.92e-2)" "unprognostic (1.34e-1)" "unprognostic (2.71e-2)" "unprognostic (9.73e-2)" "unprognostic (6.11e-2)" "unprognostic (9.86e-5)" "unprognostic (3.69e-2)" 20.0 3.7 7.3 11.9 10.4 0.0 13.0 8.3 18.5 9.5 6.9 15.1 6.1 7.1 2.7 6.9 14.3 10.1 15.1 11.2 6.9 6.8 4.0 20.5 0.4 3.1 5.0 17.2 8.1 10.1 19.4 0.2 3.8 127.7 7.6 3.9 11.9 6.9 1.4 4.7 9.1 10.8 5.4 2.7 11.0 1.1 6.4 3.3 7.9 1.6 1.7 15.8 9.0 5.7 3.2 22.5 0.5 6.3 11.5 11.1 0.3 2.8 5.8 0.4 0.8 4.2 48.1 0.0 0.3 7.5 8.8 1.8 4.9 3.5 0.8 0.0 4.7 0.0 0.1 1.1 1.0 0.0 0.1 8.1 0.8 11.5 2.3 9.4 6.1 0.0 0.0 0.4 6.6 0.0 0.0 0.7 9.1 0.0 2.5 0.0 0.0 0.2 10.3 6.6 0.7 2.1 3.5 0.0 0.1 1.0 16.8 0.0 5.1 27.4 6.0 3.8 2.4 0.1 0.0 0.0 11.7 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.3 10.4 8.3 18.5 11.2 6.9 3.1 5.0 3.8 5.4 6.4 5.7 0.6 0.0 1.1 18.6 0.2 4.8 21.6 20.6 9.1 7.5 16.1 10.3 18.0 18.6 19.4 12.9 2.1 0.0 0.1 15.9 0.0 1.1 0.5 2.8 3.7 2.2 15.7 2.7 68.0 7.4 0.0 27.6 10.7 2.9 0.0 30.4 3.6 5.8 0.0 1.7 53.0 9.8 10.2 0.0 6.2 0.8 15.5 0.7 0.0 2.8 0.0 23.1 0.0 27.6 2.6 11.4 24.0 15.4 0.0 102.9 13.1 10.8 16.0 1.3 0.0 14.7 5.8 3.1 6.2 4.1 5.4 0.0 0.5 9.8 13.8 25.3 STX10 "hsyn10, SYN10" ENSG00000104915 "Syntaxin 10" O60499 19 13144058-13150383 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035303, HPA056439" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Vesicles" "HPA035303: AB_10671932, HPA056439: AB_2683135" "unprognostic (1.72e-2)" "unprognostic (2.26e-2)" "unprognostic (1.62e-2)" "unprognostic (6.73e-2)" "unprognostic (2.40e-1)" "unprognostic (1.21e-2)" "unprognostic (2.54e-3)" "prognostic favorable (8.26e-4)" "unprognostic (4.09e-1)" "unprognostic (3.66e-2)" "unprognostic (4.57e-2)" "unprognostic (9.21e-2)" "prognostic unfavorable (1.69e-7)" "unprognostic (2.39e-3)" "unprognostic (7.95e-2)" "unprognostic (2.23e-1)" "unprognostic (2.98e-2)" 45.3 58.7 42.1 35.6 44.3 72.3 47.1 45.3 52.3 65.5 47.0 57.2 47.7 48.7 17.1 80.7 49.6 29.5 56.1 42.2 41.7 60.9 78.8 66.9 42.5 44.6 43.3 50.7 48.3 27.9 49.1 17.0 43.1 49.9 19.8 11.6 52.0 20.4 35.8 68.2 60.7 20.9 40.7 87.0 60.3 17.7 43.6 35.3 56.6 16.6 28.2 51.4 55.4 48.5 99.9 68.8 51.8 138.1 51.5 52.8 17.2 55.4 49.4 46.1 48.4 31.8 88.3 66.5 80.5 66.8 33.7 76.3 44.9 67.0 26.6 113.4 86.0 60.8 154.4 66.5 38.2 71.4 63.2 54.3 55.3 57.4 37.2 62.8 58.1 85.9 32.9 34.6 31.8 87.2 105.6 125.2 55.2 51.3 112.5 117.3 54.1 96.6 44.4 47.2 60.0 121.3 57.9 66.2 127.6 14.9 45.1 67.9 58.4 75.3 38.7 145.9 77.5 78.1 75.2 57.0 98.0 172.8 59.8 41.5 162.3 120.4 48.1 128.4 40.7 39.9 41.4 48.7 119.1 40.3 36.3 37.3 267.6 32.1 151.5 31.2 51.4 80.7 42.1 44.3 45.3 52.3 42.2 41.7 44.6 43.3 43.1 40.7 43.6 48.5 31.6 16.0 21.6 13.1 29.9 35.4 34.5 52.0 31.3 21.3 43.0 37.5 12.6 30.0 53.6 20.2 6.2 17.7 32.2 54.3 27.4 42.5 1.0 23.9 28.3 31.3 16.3 33.2 16.6 56.1 26.2 27.6 40.8 24.7 53.8 33.7 31.1 18.8 82.4 13.5 11.8 48.0 46.8 86.7 45.8 3.0 25.1 62.0 48.0 7.5 86.1 21.4 48.4 11.1 14.0 57.0 53.8 31.2 25.3 19.9 77.9 28.3 38.2 17.1 26.3 21.2 31.0 9.0 16.2 38.6 43.2 19.4 39.1 23.6 55.5 38.4 SYBU "FLJ20366, GOLSYN, KIAA1472, OCSYN, SNPHL" ENSG00000147642 Syntabulin Q9NX95 8 109573978-109691791 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 140.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 200.5;Horizontal cells: 95.9;Inhibitory neurons: 129.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "memory B-cell: 6.4;naive B-cell: 3.2" "Lineage enriched" "Detected in single" 27 "B-cells: 6.4" "Cell line enhanced" "Detected in many" "HaCaT: 24.4;PC-3: 25.7;SK-BR-3: 51.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053057 Uncertain Supported Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA053057: AB_2682028" "unprognostic (4.69e-2)" "unprognostic (1.40e-1)" "unprognostic (2.46e-1)" "unprognostic (1.31e-1)" "unprognostic (1.18e-1)" "unprognostic (4.27e-1)" "prognostic favorable (7.74e-4)" "unprognostic (1.22e-2)" "unprognostic (1.37e-1)" "unprognostic (2.16e-1)" "unprognostic (3.13e-1)" "unprognostic (5.52e-2)" "unprognostic (1.87e-3)" "unprognostic (1.68e-1)" "unprognostic (6.05e-3)" "unprognostic (6.89e-2)" "unprognostic (4.27e-2)" 32.2 38.7 39.1 3.2 42.0 0.0 22.2 44.5 52.4 10.7 4.4 15.4 10.9 5.6 11.5 5.6 20.1 10.3 6.9 42.4 58.6 4.2 52.1 8.8 4.4 24.2 34.0 9.2 140.5 1.5 30.4 2.5 36.6 8.2 19.7 26.1 21.5 11.0 3.8 9.6 12.0 6.9 22.8 1.0 28.2 1.8 50.8 5.4 12.3 7.7 7.8 5.9 8.8 30.2 8.6 5.2 3.6 0.0 0.5 0.6 2.5 3.1 0.0 0.0 0.0 7.9 5.4 0.7 0.5 2.5 1.2 24.4 0.8 5.7 0.0 0.1 11.6 0.0 15.2 8.2 6.2 0.0 0.0 1.9 7.7 0.0 7.2 0.4 3.3 0.6 0.4 1.6 3.5 0.2 0.2 0.0 0.7 7.7 25.7 0.0 0.0 0.0 9.5 2.2 16.3 1.9 6.9 51.4 1.7 2.5 6.8 0.3 5.0 0.3 2.0 0.1 1.5 1.5 0.1 0.5 10.8 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 6.4 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 39.1 42.0 44.5 52.4 42.4 58.6 24.2 34.0 36.6 22.8 50.8 30.2 39.3 9.6 7.7 16.0 4.3 5.7 2.5 8.3 17.1 46.1 10.9 9.1 2.4 30.0 18.0 11.0 8.4 4.6 0.1 3.6 3.9 5.4 1.4 29.3 3.4 11.8 34.5 0.0 200.5 9.4 0.9 7.9 5.6 20.9 0.0 0.7 10.0 39.1 0.3 95.9 129.6 22.2 2.0 0.8 4.2 0.4 2.1 0.3 1.8 21.5 0.7 2.1 0.0 22.1 5.7 3.9 9.8 0.4 0.1 11.8 16.2 0.1 15.6 7.4 0.0 16.5 4.2 1.3 1.5 3.5 3.3 0.7 0.6 0.1 13.7 4.2 SYNCRIP "dJ3J17.2, GRY-RBP, hnRNP-Q, HNRNPQ, HNRPQ1, NSAP1" ENSG00000135316 "Synaptotagmin binding cytoplasmic RNA interacting protein" O60506 6 85607779-85644063 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Translation regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010895, HPA041275, HPA069241" Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA 1300000 "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Vesicles, Cytosol" "CAB010895: AB_261964, HPA041275: AB_2677389, HPA069241: " "unprognostic (1.01e-1)" "unprognostic (3.49e-2)" "unprognostic (1.02e-2)" "unprognostic (1.20e-1)" "unprognostic (1.49e-2)" "unprognostic (6.22e-2)" "prognostic unfavorable (6.28e-5)" "unprognostic (6.84e-2)" "unprognostic (6.48e-2)" "prognostic favorable (5.59e-4)" "unprognostic (1.58e-2)" "unprognostic (1.43e-1)" "unprognostic (4.86e-2)" "unprognostic (1.37e-1)" "unprognostic (2.34e-1)" "unprognostic (1.00e-1)" "unprognostic (4.11e-1)" 60.5 43.2 25.1 80.2 28.0 67.3 55.6 28.1 24.8 51.4 26.0 54.1 48.0 46.1 41.7 75.8 34.0 47.8 45.6 22.8 29.9 53.1 66.7 49.4 88.1 28.9 27.4 36.2 51.9 56.9 19.5 68.5 31.0 44.9 62.7 36.0 41.4 46.5 55.9 43.5 44.0 62.1 27.7 51.3 50.0 38.7 27.6 91.0 87.3 56.0 101.9 81.5 40.8 29.0 209.5 147.5 239.9 157.1 150.8 165.3 162.8 258.6 218.1 244.4 239.9 250.4 132.6 480.0 200.0 262.8 203.1 197.4 331.1 269.0 405.4 175.9 163.9 405.4 152.8 165.2 130.3 497.6 177.7 141.8 179.6 276.4 272.1 138.4 254.9 133.2 451.5 210.0 295.1 243.5 255.2 218.9 231.5 209.4 153.2 364.7 345.5 209.9 236.2 307.1 239.5 184.6 188.5 180.8 128.6 137.2 150.8 360.9 247.4 165.8 142.7 189.8 374.2 138.0 260.5 275.4 165.4 328.7 251.4 1.8 24.7 8.8 30.6 36.2 30.0 21.9 27.1 27.5 37.7 21.2 23.4 27.7 3.0 36.1 41.1 29.0 31.6 24.6 25.1 28.0 28.1 24.8 22.8 29.9 28.9 27.4 31.0 27.7 27.6 29.0 106.9 115.4 119.5 26.4 73.0 148.2 160.9 124.4 83.6 44.5 89.0 82.8 88.9 52.9 126.7 46.0 16.7 101.3 97.2 50.4 54.8 120.7 117.6 105.1 156.2 100.7 56.7 65.6 24.0 99.6 133.3 101.8 79.5 152.1 61.4 81.6 57.5 81.4 96.9 62.2 24.3 78.0 79.3 71.1 67.1 28.7 73.7 92.9 53.4 31.9 90.7 45.1 57.7 32.2 40.9 130.0 45.7 64.3 97.4 133.0 47.7 80.7 84.6 42.2 19.7 158.6 131.8 93.7 65.8 142.4 141.6 118.1 81.6 85.8 106.7 159.8 SYT13 KIAA1427 ENSG00000019505 "Synaptotagmin 13" Q7L8C5 11 45240302-45286341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;gallbladder: 20.8;pituitary gland: 16.8" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 336.8" "Group enriched" "Detected in many" 5 "breast cancer: 13.5;colorectal cancer: 7.4;pancreatic cancer: 19.9;renal cancer: 16.9;stomach cancer: 11.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 19.1;NTERA-2: 8.8;RPTEC TERT1: 56.8;SCLC-21H: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046224, HPA056602" Uncertain Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA046224: AB_10961288, HPA056602: AB_2683185" "unprognostic (4.96e-2)" "unprognostic (1.06e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (7.79e-5)" "unprognostic (1.00e-2)" "unprognostic (4.17e-2)" "unprognostic (3.75e-2)" "unprognostic (9.83e-3)" "unprognostic (2.19e-1)" "unprognostic (7.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (5.66e-3)" "unprognostic (2.94e-2)" "unprognostic (1.76e-1)" "unprognostic (8.70e-2)" "unprognostic (5.13e-2)" 0.1 4.7 7.0 1.5 12.7 0.0 0.2 1.7 30.1 0.0 0.0 12.2 12.5 0.2 0.0 0.0 0.2 20.8 5.2 18.0 11.5 8.9 0.3 0.5 0.0 5.7 1.2 0.0 7.1 0.4 16.8 0.0 5.4 1.8 12.6 11.3 1.9 0.0 0.1 0.2 12.8 0.8 0.0 0.1 11.0 1.7 9.0 0.3 1.6 0.1 0.0 0.0 0.0 5.2 0.0 19.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 1.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 8.8 0.0 0.2 0.0 0.0 0.0 56.8 0.0 15.0 0.7 0.0 0.0 0.1 0.7 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 12.7 1.7 30.1 18.0 11.5 5.7 1.2 5.4 0.0 9.0 5.2 0.0 0.0 0.0 4.6 0.1 0.0 0.2 0.0 0.0 3.3 0.1 0.3 15.3 17.2 0.0 3.7 25.0 0.0 0.0 10.2 5.9 1.2 3.1 0.4 0.2 0.1 336.8 0.0 41.6 0.6 0.0 1.7 3.6 2.0 0.0 2.5 0.0 0.0 0.0 1.7 43.8 37.3 4.1 0.0 0.0 9.7 0.3 0.0 0.0 5.6 0.0 0.7 0.0 1.5 3.5 8.2 14.3 0.0 0.0 2.3 13.9 0.5 0.0 2.7 0.0 0.0 0.2 2.0 0.2 0.0 0.0 0.0 0.0 0.0 32.8 0.2 SYT14 "FLJ34198, sytXIV" ENSG00000143469 "Synaptotagmin 14" Q8NB59 1 209900923-210171389 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 7.0;retina: 1.9;testis: 3.2;thyroid gland: 5.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 208.7;Inhibitory neurons: 213.9;Oligodendrocyte precursor cells: 152.8;Oligodendrocytes: 197.6" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.9" "Region enriched" "Detected in some" 4 "cerebellum: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 9.7;GAMG: 6.7;hTERT-HME1: 4.7;SCLC-21H: 6.5;U-138 MG: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036963 Supported Vesicles NA NA "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA036963: AB_10670378" "unprognostic (1.38e-4)" "unprognostic (8.62e-3)" "unprognostic (1.93e-1)" "unprognostic (3.90e-4)" "unprognostic (1.97e-1)" "unprognostic (4.43e-5)" "unprognostic (1.92e-1)" "unprognostic (1.88e-2)" "unprognostic (6.85e-2)" "unprognostic (1.56e-2)" "unprognostic (3.81e-1)" "unprognostic (4.85e-3)" "unprognostic (2.30e-4)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (3.33e-3)" 0.0 0.7 0.4 0.0 0.6 0.0 0.0 7.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.2 0.0 0.6 0.0 0.4 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.2 0.2 0.0 5.0 0.0 0.0 0.0 0.0 1.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 9.7 2.2 1.2 0.0 0.0 0.0 0.0 0.1 6.7 3.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 4.7 1.1 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 3.6 0.0 0.3 0.0 0.0 0.0 0.0 1.9 6.5 2.0 0.0 0.0 3.6 0.8 0.0 0.0 1.6 6.4 3.2 0.0 0.9 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 7.0 1.0 0.4 0.3 0.4 0.2 0.4 0.1 0.2 1.6 0.0 0.0 0.0 30.3 0.0 0.0 0.1 0.0 0.0 30.1 0.2 0.0 2.2 0.0 0.0 0.0 27.1 0.0 0.0 0.0 3.9 0.3 17.0 11.6 2.9 0.2 0.0 0.0 208.7 0.6 0.0 0.2 0.0 29.3 0.0 0.9 0.0 0.0 0.0 52.2 213.9 0.0 0.0 0.0 0.0 5.0 0.6 0.2 0.0 3.7 0.0 1.6 0.0 152.8 197.6 0.3 0.0 0.0 0.0 0.7 0.0 0.4 0.0 29.4 0.0 0.9 0.2 6.0 16.8 0.0 0.0 0.0 0.1 0.7 0.0 0.2 TASL "CXorf21, FLJ11577" ENSG00000120280 "TLR adaptor interacting with endolysosomal SLC15A4" Q9HAI6 X 30558809-30577766 "Disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.5;lymphoid tissue: 10.9" "Cell type enriched" "Detected in some" 5 "Hofbauer cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "THP-1: 166.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001185 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "HPA001185: AB_1078591" "unprognostic (1.37e-1)" "unprognostic (2.52e-2)" "unprognostic (4.37e-2)" "unprognostic (2.27e-2)" "unprognostic (3.47e-2)" "unprognostic (5.25e-3)" "unprognostic (9.07e-3)" "unprognostic (5.94e-3)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (3.43e-1)" "unprognostic (3.60e-1)" "unprognostic (1.66e-3)" "unprognostic (8.99e-2)" "unprognostic (1.98e-2)" "unprognostic (3.45e-2)" "unprognostic (3.23e-2)" 1.8 1.8 0.6 10.9 0.6 19.5 2.1 0.7 1.0 1.1 1.1 3.5 4.7 0.6 0.4 1.6 0.8 3.9 0.6 0.7 0.6 1.1 2.4 4.7 10.5 1.3 1.1 0.3 0.3 0.7 0.3 2.9 1.3 1.0 3.4 0.2 1.0 0.6 0.1 0.7 3.0 2.2 0.9 9.8 3.6 0.3 1.5 5.8 0.6 0.4 10.2 4.1 0.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.2 0.0 0.0 13.8 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 21.5 0.0 0.0 0.0 20.5 0.0 21.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 166.0 0.0 0.0 0.0 0.0 0.1 15.0 1.6 7.5 0.0 23.9 0.0 8.6 21.9 24.1 1.6 19.8 0.3 23.0 2.0 1.1 25.3 23.6 1.8 1.3 30.6 7.1 44.4 45.9 3.4 8.0 0.6 0.6 0.7 1.0 0.7 0.6 1.3 1.1 1.3 0.9 1.5 2.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 TBC1D14 KIAA1322 ENSG00000132405 "TBC1 domain family member 14" Q9P2M4 4 6909242-7033118 "Plasma proteins, Predicted intracellular proteins" Autophagy "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 197.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036930, HPA067398" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" Nucleoplasm "HPA036930: AB_10670155, HPA067398: AB_2685833" "unprognostic (3.05e-2)" "unprognostic (7.48e-3)" "unprognostic (4.80e-3)" "unprognostic (8.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.78e-3)" "unprognostic (9.63e-2)" "unprognostic (5.25e-2)" "unprognostic (9.71e-2)" "unprognostic (7.65e-2)" "unprognostic (1.80e-1)" "unprognostic (2.90e-1)" "prognostic favorable (5.28e-10)" "unprognostic (1.56e-1)" "unprognostic (3.50e-1)" "unprognostic (5.13e-3)" "unprognostic (4.12e-2)" 26.3 42.1 42.7 31.5 41.9 15.9 27.6 38.7 43.9 19.4 50.2 26.4 22.8 20.9 22.9 34.0 23.5 17.0 30.4 42.9 44.9 44.5 27.4 24.4 29.8 49.3 45.6 28.7 19.5 41.9 27.1 23.8 44.8 24.5 26.3 18.5 31.7 20.2 51.6 49.5 26.0 22.9 45.7 34.9 58.5 30.0 48.7 40.1 19.2 41.3 26.9 19.8 22.2 44.2 34.5 36.8 40.4 45.5 32.8 27.4 24.5 27.0 29.3 24.7 21.1 38.3 69.8 54.9 15.6 32.5 62.8 24.5 68.4 61.7 30.0 15.5 22.2 91.8 23.8 40.4 22.7 42.0 197.9 21.3 85.8 23.4 38.3 31.5 23.5 51.2 88.6 19.3 30.2 22.3 64.9 42.5 54.9 41.1 40.8 80.2 53.2 59.9 36.8 23.9 61.6 44.0 22.4 24.1 84.3 31.2 33.3 39.4 23.7 27.2 20.5 24.0 40.3 36.7 91.6 55.7 25.4 53.2 26.6 2.6 13.2 5.6 8.6 8.2 13.1 8.1 9.3 9.3 10.7 8.3 6.9 6.6 40.6 8.6 3.9 11.5 11.9 10.8 42.7 41.9 38.7 43.9 42.9 44.9 49.3 45.6 44.8 45.7 48.7 44.2 8.4 6.4 17.7 22.5 15.5 9.1 7.0 15.8 15.9 10.2 21.1 16.3 4.6 10.0 14.8 14.7 14.6 12.5 16.3 17.7 19.6 11.5 68.0 12.3 10.3 7.8 6.6 7.2 25.6 10.2 7.1 9.5 14.8 11.9 7.6 18.9 8.2 24.4 26.0 25.2 25.1 15.7 10.2 33.6 8.7 41.0 7.2 27.8 19.6 27.2 24.4 13.4 16.5 51.8 27.0 11.8 14.2 8.6 15.4 12.9 12.8 19.8 10.7 6.6 0.0 12.7 7.1 17.7 18.0 19.8 11.9 16.4 16.3 12.5 19.9 10.1 TBC1D5 KIAA0210 ENSG00000131374 "TBC1 domain family member 5" Q92609 3 17157162-18444817 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Astrocytes: 226.6;Excitatory neurons: 333.2;Inhibitory neurons: 350.5;Microglial cells: 324.2;Oligodendrocyte precursor cells: 341.8;Oligodendrocytes: 565.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035125, HPA035126" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "Golgi apparatus" "HPA035125: AB_2674479, HPA035126: AB_10670696" "unprognostic (1.87e-1)" "unprognostic (3.57e-1)" "unprognostic (2.86e-2)" "unprognostic (3.19e-1)" "unprognostic (1.60e-1)" "unprognostic (4.30e-3)" "unprognostic (3.07e-2)" "unprognostic (3.31e-1)" "unprognostic (3.56e-2)" "unprognostic (6.27e-2)" "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "prognostic favorable (1.75e-7)" "unprognostic (1.25e-1)" "unprognostic (1.56e-1)" "unprognostic (5.72e-2)" "unprognostic (7.07e-2)" 17.9 17.4 13.7 17.0 21.1 25.2 18.6 18.2 15.5 20.1 6.0 13.5 10.8 17.6 12.1 16.8 22.5 19.2 15.8 13.8 16.1 19.9 14.7 18.0 23.1 21.9 17.7 28.1 18.3 25.7 8.5 17.5 22.8 14.0 13.9 10.9 14.1 16.4 9.3 14.0 13.8 18.3 18.3 24.0 13.8 18.9 16.0 20.3 30.0 11.3 23.2 14.8 10.1 29.9 26.3 28.8 23.2 22.0 45.0 65.5 25.4 27.6 39.7 17.7 15.3 14.0 23.2 48.5 29.1 56.3 27.1 8.0 20.6 33.6 36.6 43.0 7.9 46.6 11.1 16.5 28.8 45.7 39.0 42.6 39.3 38.5 23.2 39.8 40.9 28.3 29.6 43.6 43.5 17.6 22.5 10.5 19.1 16.8 30.0 48.9 29.6 34.7 26.3 20.0 8.8 41.0 52.5 12.2 18.6 21.7 34.6 37.6 44.7 48.7 21.6 25.6 30.4 25.2 36.6 46.7 37.5 42.3 46.5 11.7 8.1 11.9 5.8 6.5 7.5 10.3 4.4 4.2 9.2 11.3 3.2 3.8 10.4 4.3 6.3 5.8 5.2 4.8 13.7 21.1 18.2 15.5 13.8 16.1 21.9 17.7 22.8 18.3 16.0 29.9 40.4 16.0 35.0 226.6 56.0 18.4 20.0 15.8 42.7 20.3 23.0 19.9 18.6 25.8 27.8 14.7 10.4 17.1 28.9 9.2 5.9 17.7 64.1 19.6 28.9 30.7 13.1 31.3 333.2 9.9 16.7 32.5 20.4 28.2 18.9 31.5 34.6 19.9 21.4 35.3 350.5 13.4 10.2 35.6 22.9 40.2 30.7 34.9 14.2 324.2 23.2 26.6 32.0 341.8 565.6 12.3 9.1 30.5 20.7 9.8 13.7 15.9 16.3 22.3 6.6 34.0 20.4 20.7 25.5 28.4 17.0 8.2 30.0 35.5 14.5 17.6 TECPR1 "DKFZP434B0335, FLJ23419, FLJ90593, KIAA1358" ENSG00000205356 "Tectonin beta-propeller repeat containing 1" Q7Z6L1 7 98214624-98252232 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "pancreas: 84.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Rod photoreceptor cells: 66.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021061 Approved Supported Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "HPA021061: AB_1847687" "unprognostic (8.10e-3)" "unprognostic (7.89e-2)" "unprognostic (9.05e-3)" "unprognostic (5.00e-3)" "unprognostic (2.03e-1)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (1.45e-2)" "unprognostic (1.72e-1)" "unprognostic (1.88e-1)" "prognostic favorable (8.12e-4)" "unprognostic (2.48e-1)" "unprognostic (2.54e-1)" "unprognostic (1.38e-1)" "unprognostic (3.24e-1)" "unprognostic (9.46e-2)" "unprognostic (6.12e-2)" 8.4 7.0 11.7 10.4 12.3 6.1 8.0 6.5 12.5 6.4 4.7 8.5 9.2 6.8 3.0 9.8 6.9 5.7 9.9 12.7 12.9 7.7 9.2 13.3 11.8 11.8 11.2 5.7 84.9 3.1 16.7 8.6 12.7 11.6 5.0 10.2 18.9 3.8 9.1 5.9 10.8 4.7 8.5 18.6 18.3 4.6 11.5 9.5 9.6 5.0 6.7 6.8 6.6 8.2 4.4 6.1 8.4 18.3 7.2 4.3 6.2 9.1 5.0 7.1 8.7 5.8 5.4 3.6 14.4 10.6 8.8 2.8 5.7 4.2 3.0 8.8 8.0 5.3 9.4 5.3 8.5 6.5 9.9 7.5 3.4 6.9 5.3 6.6 25.2 15.1 3.6 15.0 5.4 7.2 9.4 6.8 3.3 8.6 5.9 7.8 8.5 17.7 5.4 4.8 15.0 16.9 5.4 14.9 8.5 6.1 4.8 9.2 26.0 6.7 11.5 17.4 7.6 17.6 9.8 1.9 14.0 5.6 12.5 2.5 2.9 0.9 2.2 3.2 1.3 1.8 2.9 1.7 1.8 1.6 4.8 4.2 3.5 1.0 4.9 2.4 3.0 2.3 11.7 12.3 6.5 12.5 12.7 12.9 11.8 11.2 12.7 8.5 11.5 8.2 32.2 9.6 18.4 18.3 12.3 2.3 2.2 3.7 1.8 37.1 7.0 5.8 11.2 7.2 7.0 5.5 106.3 6.0 10.9 16.0 1.9 6.4 2.1 6.9 5.5 22.9 29.3 2.1 21.1 13.4 9.8 7.2 35.7 8.1 8.2 11.0 21.0 8.5 13.7 32.0 17.8 22.9 10.2 20.5 4.0 2.2 7.2 14.2 1.8 16.9 19.5 11.4 14.4 10.1 10.1 11.9 10.3 3.4 17.4 4.1 10.8 3.6 7.7 66.7 0.0 7.5 7.4 5.5 4.5 7.1 1.8 3.4 16.0 9.0 10.0 2.9 TEP1 "p240, TLP1, TP1, TROVE1, VAULT2" ENSG00000129566 "Telomerase associated protein 1" Q99973 14 20365667-20413501 "Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 23.9;Gastric mucus-secreting cells: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029206 Supported Nucleoplasm,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA029206: AB_10601271" "unprognostic (4.53e-2)" "unprognostic (2.81e-2)" "unprognostic (1.26e-1)" "prognostic favorable (9.58e-4)" "unprognostic (2.27e-1)" "unprognostic (2.76e-1)" "unprognostic (2.66e-2)" "unprognostic (1.43e-1)" "unprognostic (6.81e-2)" "unprognostic (1.42e-2)" "unprognostic (1.92e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "unprognostic (2.18e-1)" "unprognostic (6.18e-2)" "unprognostic (3.00e-1)" 9.4 7.8 3.4 12.1 4.1 5.1 8.7 3.2 4.0 7.8 6.0 17.4 28.0 6.9 7.3 6.8 7.2 10.7 6.8 3.3 4.3 6.5 6.5 11.0 15.0 6.0 5.3 6.2 6.2 13.7 5.7 6.6 5.1 7.9 17.9 5.0 8.3 6.3 10.3 7.9 15.5 9.7 3.8 14.8 9.6 2.3 5.8 10.2 8.1 5.1 15.1 7.5 7.8 5.2 9.2 4.2 4.1 4.5 26.1 9.9 7.3 6.8 6.0 4.0 5.1 8.7 10.2 8.1 4.2 17.0 7.3 9.3 3.5 13.6 6.8 7.8 3.5 9.5 9.4 5.7 7.5 8.0 16.1 14.1 11.8 6.5 5.2 17.1 15.2 6.7 3.1 5.8 14.0 5.4 4.7 5.8 1.8 28.4 3.6 12.2 10.2 2.8 13.2 13.8 1.2 1.9 5.4 12.8 4.2 11.8 6.5 4.9 20.1 15.5 10.6 4.9 1.9 12.9 6.9 5.1 3.7 6.9 5.5 3.6 2.3 0.0 1.0 2.8 1.0 1.7 0.5 1.0 0.8 2.4 0.5 0.6 4.5 0.5 2.9 5.4 0.6 0.3 3.4 4.1 3.2 4.0 3.3 4.3 6.0 5.3 5.1 3.8 5.8 5.2 3.7 9.6 14.1 13.1 8.4 2.8 4.8 3.1 2.8 0.3 3.2 2.8 3.2 8.6 5.6 1.8 2.1 2.0 14.3 23.9 1.9 4.8 0.2 2.9 4.2 5.8 4.2 2.1 1.9 5.1 2.5 3.4 25.5 4.2 10.8 2.6 8.2 4.9 6.4 0.0 2.1 12.8 0.0 10.4 4.6 1.3 5.0 10.2 5.4 16.9 12.9 2.6 7.2 4.5 3.9 6.0 12.8 3.8 8.4 5.1 21.8 3.8 12.2 2.6 0.0 5.1 6.1 0.0 0.6 2.4 1.4 1.9 5.0 2.2 8.3 4.9 TFG "FLJ36137, SPG57, TF6" ENSG00000114354 "Trafficking from ER to golgi regulator" Q92734 3 100709295-100748964 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019473, HPA052206" Approved Supported Vesicles,Cytosol No No 320000 "Cluster 38: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" Vesicles Cytosol "HPA019473: AB_1857936, HPA052206: AB_2681760" "unprognostic (1.14e-1)" "unprognostic (3.58e-2)" "unprognostic (1.46e-1)" "unprognostic (2.94e-2)" "unprognostic (1.46e-1)" "unprognostic (4.14e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (3.31e-3)" "unprognostic (1.42e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (4.58e-3)" "unprognostic (3.72e-2)" "unprognostic (2.82e-1)" "unprognostic (8.55e-2)" "unprognostic (3.33e-1)" "unprognostic (8.45e-2)" 62.2 73.0 40.7 37.2 40.4 37.4 52.4 43.5 46.4 53.9 46.7 63.8 89.8 52.0 78.5 85.7 51.2 56.4 82.6 41.3 45.4 71.9 113.9 55.6 29.4 44.2 43.2 48.2 66.7 89.0 64.1 79.2 44.4 47.9 69.6 40.9 60.6 61.3 75.5 58.9 76.6 66.5 43.2 42.6 54.4 47.7 42.3 40.6 64.1 58.2 54.9 61.6 57.3 44.4 203.8 107.5 126.7 79.0 160.1 176.4 163.9 141.1 190.4 182.5 213.0 136.0 96.1 24.7 103.3 180.4 141.3 143.1 143.4 161.5 216.2 123.8 87.4 99.7 69.3 130.0 183.3 70.2 51.8 149.3 216.6 108.4 190.8 165.1 165.5 44.5 73.1 63.5 191.9 143.9 63.3 56.7 122.5 193.8 169.3 55.5 77.8 89.0 226.5 125.9 96.4 93.1 95.0 118.2 175.8 103.4 141.7 103.1 113.1 103.0 130.8 48.4 104.4 56.2 65.8 92.1 171.2 79.7 130.7 84.3 43.6 42.8 30.8 45.2 37.4 37.4 31.6 34.5 43.1 35.9 29.4 29.7 26.1 43.1 44.8 29.3 41.0 37.0 40.7 40.4 43.5 46.4 41.3 45.4 44.2 43.2 44.4 43.2 42.3 44.4 67.9 60.9 36.9 46.4 43.3 136.6 105.9 183.6 69.4 46.8 58.0 50.2 83.5 48.6 93.1 36.8 25.0 211.6 43.1 111.8 137.0 190.3 101.5 70.8 70.4 70.2 52.6 27.1 54.8 107.7 201.5 97.8 47.4 79.0 76.8 62.9 53.9 68.4 86.2 57.2 59.2 128.5 122.1 27.3 84.9 45.5 70.8 43.6 64.0 38.4 98.5 88.0 28.8 49.3 55.0 130.5 91.0 74.1 75.8 133.5 202.5 106.4 63.9 60.3 39.5 81.3 87.2 79.2 51.5 68.0 118.9 284.4 43.2 90.0 97.2 123.0 TIPRL "dJ69E11.3, MGC3794, TIP41, TIPRL1" ENSG00000143155 "TOR signaling pathway regulator" O75663 1 168178962-168202109 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027995, HPA054282" Approved Supported Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Vesicles, Cytosol" "HPA027995: AB_10602900, HPA054282: AB_2682435" "unprognostic (3.18e-2)" "unprognostic (1.05e-1)" "unprognostic (5.05e-2)" "unprognostic (3.17e-1)" "unprognostic (3.80e-1)" "unprognostic (2.35e-3)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.82e-2)" "unprognostic (3.32e-2)" "unprognostic (1.12e-2)" "unprognostic (4.30e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (1.45e-8)" "unprognostic (3.23e-1)" "unprognostic (1.57e-1)" "unprognostic (5.55e-2)" "unprognostic (8.61e-2)" 16.3 14.9 15.5 19.6 16.3 33.8 21.0 15.0 20.1 17.7 12.8 22.2 19.0 23.2 16.8 20.1 14.3 16.8 23.7 16.8 17.0 17.8 22.5 14.9 22.2 14.0 13.4 17.4 15.9 27.4 13.6 17.5 14.4 18.4 22.0 14.7 12.0 17.3 24.4 16.3 18.5 22.7 13.4 16.3 15.4 18.2 15.1 30.1 17.4 23.0 19.9 18.7 13.6 15.7 69.4 31.0 45.9 41.6 36.7 53.1 27.5 50.5 53.0 54.6 48.4 48.3 50.1 49.0 68.2 48.7 40.1 81.8 34.5 49.3 52.6 47.2 36.4 47.3 29.2 22.9 64.5 94.7 62.0 43.2 62.8 47.4 62.7 36.0 58.1 75.4 69.0 66.3 47.7 25.4 84.9 49.0 37.0 96.7 54.2 41.1 47.0 66.4 49.7 33.9 29.6 66.1 39.3 54.6 102.2 51.6 59.9 96.3 53.4 45.6 52.4 43.6 69.7 72.2 80.5 108.1 29.8 61.4 53.4 71.6 26.7 36.8 22.0 32.1 22.1 27.3 25.7 23.8 31.6 27.6 22.8 22.4 34.5 29.6 33.9 23.4 36.0 28.2 15.5 16.3 15.0 20.1 16.8 17.0 14.0 13.4 14.4 13.4 15.1 15.7 52.1 25.6 20.4 9.4 39.7 48.2 42.1 70.4 50.1 27.3 31.3 36.2 46.3 22.8 40.7 22.0 16.7 44.2 49.0 37.1 29.4 68.5 53.4 36.0 50.1 43.4 24.0 32.6 41.6 88.9 62.8 47.3 24.5 30.8 40.0 35.2 36.0 33.5 65.1 52.2 37.9 33.9 44.7 26.6 41.1 15.4 37.6 42.6 30.2 19.7 61.0 43.9 51.5 22.1 21.3 69.7 27.7 38.0 37.1 43.3 35.9 77.2 36.1 20.8 26.3 35.4 51.1 151.5 51.6 56.0 41.8 29.0 48.0 84.5 38.5 37.5 TM4SF18 L6D ENSG00000163762 "Transmembrane 4 L six family member 18" Q96CE8 3 149318498-149334414 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 33.9" "Group enriched" "Detected in many" 4 "Adipocytes: 226.1;Endothelial cells: 188.9;Hepatic stellate cells: 151.0" "Cancer enhanced" "Detected in all" "renal cancer: 17.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 94.8;EFO-21: 194.9;GAMG: 38.7;HUVEC TERT2: 65.9;NTERA-2: 47.2" "Low region specificity" "Detected in many" "HPA053639, HPA069378" Approved Supported Vesicles,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Cytosol "HPA053639: , HPA069378: AB_2686133" "unprognostic (2.25e-1)" "unprognostic (3.68e-1)" "unprognostic (4.76e-2)" "unprognostic (1.08e-1)" "unprognostic (9.11e-3)" "unprognostic (1.05e-2)" "prognostic favorable (8.63e-4)" "unprognostic (2.84e-1)" "unprognostic (6.13e-3)" "unprognostic (1.64e-1)" "unprognostic (7.90e-3)" "unprognostic (1.75e-1)" "unprognostic (5.71e-2)" "unprognostic (3.56e-3)" "unprognostic (1.65e-1)" "unprognostic (3.01e-1)" "unprognostic (1.97e-1)" 21.3 5.2 9.4 4.9 9.6 0.1 16.3 9.2 11.5 8.3 10.4 3.4 3.9 7.6 4.7 3.4 6.4 10.6 8.4 9.1 10.3 19.1 7.9 9.2 6.6 12.2 9.6 3.2 9.8 6.8 3.1 17.4 11.5 4.0 3.3 1.1 4.0 6.5 5.9 2.4 3.6 14.9 10.0 33.9 3.4 1.9 12.1 2.1 12.7 5.7 5.0 6.7 2.5 10.4 0.1 94.8 3.5 0.2 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.2 1.2 0.0 194.9 0.0 38.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.3 0.0 0.3 0.1 0.7 0.0 0.0 0.0 24.7 65.9 0.0 0.0 0.0 6.2 0.7 0.0 0.2 47.2 0.0 0.0 0.1 2.6 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.5 1.5 0.1 0.1 8.4 0.1 1.2 0.0 0.5 0.1 0.1 0.5 0.0 0.1 15.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 9.4 9.6 9.2 11.5 9.1 10.3 12.2 9.6 11.5 10.0 12.1 10.4 226.1 0.0 4.4 0.3 1.6 3.2 0.2 0.0 0.6 0.2 41.4 23.9 2.8 4.3 0.0 1.8 0.0 0.0 1.0 0.0 9.8 35.2 0.4 0.7 1.1 188.9 0.0 0.0 0.0 0.2 0.0 6.2 0.0 0.9 1.3 0.3 151.0 1.1 0.1 0.0 0.1 0.0 0.0 9.1 3.0 1.8 2.1 1.2 1.8 33.7 0.6 0.4 0.0 0.5 0.6 0.9 0.0 6.8 2.5 1.3 0.0 35.8 0.7 0.0 0.0 1.5 2.5 0.2 0.5 0.2 2.8 0.0 1.1 5.2 0.0 0.6 TMBIM1 "LFG3, PP1201, RECS1" ENSG00000135926 "Transmembrane BAX inhibitor motif containing 1" Q969X1 2 218274197-218292586 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 281.2;Pancreatic endocrine cells: 294.3;Syncytiotrophoblasts: 282.1;Urothelial cells: 299.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 573.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012093, HPA070824" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA012093: AB_1858056, HPA070824: AB_2686317" "unprognostic (4.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (1.73e-3)" "unprognostic (2.34e-3)" "unprognostic (3.81e-3)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" "unprognostic (9.85e-2)" "unprognostic (3.76e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (1.69e-1)" "prognostic favorable (3.38e-4)" "unprognostic (1.22e-1)" "unprognostic (4.63e-2)" "unprognostic (2.75e-2)" "unprognostic (4.50e-1)" 231.0 120.9 118.0 84.1 135.0 96.1 165.5 124.8 123.6 146.8 112.1 143.1 152.6 119.7 92.9 333.4 97.3 135.5 123.3 109.4 131.2 123.5 170.8 175.1 55.4 194.5 144.0 93.5 240.3 125.6 50.2 172.7 150.7 97.6 140.7 15.2 155.1 89.5 219.1 185.3 174.6 127.1 139.8 65.9 212.3 25.4 134.1 41.9 158.0 185.2 106.8 172.9 215.1 144.2 183.9 66.4 3.5 47.1 404.3 170.6 188.7 175.5 217.9 103.4 117.7 169.8 449.0 40.6 123.3 263.0 194.6 305.3 59.8 399.9 100.4 151.0 23.5 264.6 41.8 205.6 183.3 2.4 252.4 161.1 370.7 210.4 265.6 108.4 111.8 6.7 169.0 75.0 182.9 6.1 2.8 46.5 2.5 382.3 60.4 5.7 28.3 33.1 142.1 573.4 2.2 3.1 58.0 214.7 122.8 36.6 56.3 39.8 168.4 182.4 50.1 84.9 64.8 35.9 45.2 17.7 179.9 41.0 105.5 352.9 136.4 298.5 107.9 172.7 91.8 77.1 98.0 89.1 93.3 61.9 64.3 70.2 167.1 66.7 221.9 25.9 116.1 190.1 118.0 135.0 124.8 123.6 109.4 131.2 194.5 144.0 150.7 139.8 134.1 144.2 47.6 73.7 25.6 20.9 37.2 81.7 96.9 85.0 51.2 2.0 28.8 26.0 26.4 78.6 66.9 69.9 0.0 139.1 51.8 266.8 13.7 175.5 0.6 45.6 42.6 50.8 22.7 66.3 2.4 281.2 146.8 61.9 110.6 78.4 50.0 16.1 28.9 50.4 104.9 0.0 2.5 67.9 52.9 45.1 50.2 2.8 54.0 69.6 46.2 14.0 22.0 22.9 48.4 5.0 35.2 294.3 177.3 59.5 30.3 151.8 204.4 37.7 34.8 1.9 13.1 35.7 45.0 1.4 12.5 86.5 101.2 282.1 41.3 9.9 69.1 299.8 TMED2 "P24A, p24b1, p24beta1, RNP24" ENSG00000086598 "Transmembrane p24 trafficking protein 2" Q15363 12 123584533-123598582 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014060 Approved Supported Vesicles NA NA 82000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA014060: AB_1856389" "unprognostic (6.36e-2)" "unprognostic (3.38e-3)" "unprognostic (5.41e-3)" "unprognostic (1.75e-2)" "unprognostic (2.98e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.57e-3)" "unprognostic (2.20e-2)" "unprognostic (4.31e-2)" "unprognostic (9.76e-3)" "unprognostic (1.03e-2)" "unprognostic (3.94e-2)" "prognostic unfavorable (2.35e-7)" "unprognostic (2.97e-1)" "unprognostic (1.63e-1)" "unprognostic (1.51e-1)" "unprognostic (9.87e-2)" 106.0 97.1 40.7 92.6 43.5 122.1 136.1 44.2 50.8 155.6 59.5 132.5 123.7 102.5 203.3 111.9 102.3 96.1 116.5 40.5 45.3 102.8 271.1 85.4 72.7 46.6 46.6 101.5 229.1 99.3 65.0 125.4 46.9 140.5 140.7 56.9 227.6 102.2 131.0 74.8 110.5 102.1 46.0 63.2 133.8 58.5 44.2 69.1 197.6 112.1 95.2 118.6 71.4 53.8 237.7 204.9 133.4 232.2 295.7 260.2 317.5 401.2 318.5 246.8 194.2 209.9 198.9 199.3 210.7 398.7 169.4 228.1 181.8 214.5 257.3 155.2 169.3 217.3 114.0 267.6 559.5 296.9 178.1 220.5 349.2 212.6 286.0 352.7 234.7 133.5 223.1 132.9 255.6 175.1 159.8 242.7 192.9 201.0 206.6 164.8 216.8 235.7 303.9 349.1 166.5 143.1 267.3 263.6 273.7 160.0 450.2 237.2 226.2 210.1 132.4 204.9 227.5 292.3 290.7 167.6 248.3 192.9 254.2 249.7 143.2 145.9 157.0 147.5 198.8 111.8 137.0 148.4 158.6 102.5 110.3 129.4 111.1 148.5 141.3 242.5 140.1 142.2 40.7 43.5 44.2 50.8 40.5 45.3 46.6 46.6 46.9 46.0 44.2 53.8 97.1 48.1 71.5 9.1 148.8 417.4 290.3 348.5 207.1 50.1 258.8 98.0 167.2 213.1 233.2 154.5 20.9 281.5 166.9 169.6 117.4 325.1 12.2 89.2 136.5 142.0 170.7 76.3 20.0 249.6 678.6 242.7 156.5 136.8 92.6 88.4 143.5 538.8 215.8 48.8 20.3 352.4 321.4 141.7 414.3 13.9 181.4 128.5 378.8 17.8 129.8 124.1 195.7 19.6 27.5 224.9 158.5 153.4 521.0 486.3 178.1 163.0 142.1 54.7 164.3 112.6 193.5 165.9 150.6 289.8 498.8 451.9 154.3 125.0 263.9 389.2 TMEM135 FLJ22104 ENSG00000166575 "Transmembrane protein 135" Q86UB9 11 87037844-87328824 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 121.8;Excitatory neurons: 99.6;Inhibitory neurons: 93.7;Oligodendrocyte precursor cells: 123.1;Oligodendrocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 88.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056685, HPA069473" Uncertain Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA056685: AB_2683208, HPA069473: AB_2686139" "unprognostic (1.55e-2)" "unprognostic (1.11e-1)" "unprognostic (2.70e-2)" "unprognostic (6.51e-2)" "unprognostic (3.10e-2)" "unprognostic (4.42e-1)" "unprognostic (1.45e-2)" "unprognostic (2.63e-1)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (1.65e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (7.34e-2)" "unprognostic (1.35e-2)" "unprognostic (1.80e-1)" 26.1 14.9 4.2 5.6 6.0 3.7 14.2 2.8 5.2 5.6 5.8 10.5 15.6 6.4 4.7 4.4 6.0 8.3 6.7 4.9 5.2 12.0 24.7 6.5 5.9 5.0 5.8 7.3 6.2 9.4 5.4 10.2 5.6 10.7 8.5 7.0 10.0 6.4 8.4 3.9 14.5 6.9 2.5 5.8 7.4 10.2 4.3 6.6 10.1 7.5 4.8 5.5 4.4 6.7 8.8 15.7 9.8 13.7 31.3 28.6 9.2 6.5 16.7 7.6 17.0 27.1 39.9 24.2 17.1 8.9 19.9 8.3 13.3 14.9 8.5 22.7 7.5 18.5 14.0 88.5 17.6 10.8 9.2 34.8 9.2 11.0 7.6 10.2 19.5 26.4 19.3 35.9 9.0 5.9 28.3 10.8 11.5 47.2 11.7 12.5 7.5 19.2 17.5 28.1 4.8 11.0 9.6 30.0 13.6 18.8 42.0 9.6 10.3 7.9 10.3 30.6 4.6 13.4 28.2 28.2 6.0 11.5 15.7 0.9 4.8 1.4 7.5 5.1 6.7 4.7 4.7 8.1 5.6 3.4 5.3 5.1 1.5 7.2 2.2 5.7 5.4 4.1 4.2 6.0 2.8 5.2 4.9 5.2 5.0 5.8 5.6 2.5 4.3 6.7 14.4 9.6 7.5 121.8 7.1 4.2 4.0 4.6 8.6 5.6 12.7 7.1 6.3 5.7 6.8 1.8 4.2 2.6 7.7 10.5 5.9 2.8 2.8 5.8 11.0 8.1 3.6 3.8 99.6 3.2 8.6 11.0 8.6 4.2 9.5 11.5 7.9 16.2 4.9 1.7 93.7 6.8 10.2 7.8 6.0 7.7 7.2 5.4 5.4 48.7 4.1 5.0 9.2 123.1 202.4 3.1 10.9 7.2 10.3 6.1 21.8 10.6 8.7 4.2 32.9 5.7 8.4 2.2 3.8 4.8 4.8 1.5 8.3 24.6 8.7 3.8 TMEM35A "FLJ14084, NACHO, TMEM35, TUF-1" ENSG00000126950 "Transmembrane protein 35A" Q53FP2 X 101078879-101096367 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.9;intestine: 36.8;seminal vesicle: 50.9" "Cell type enriched" "Detected in some" 5 "Theca cells: 37.5" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 10.1;HUVEC TERT2: 52.5;SH-SY5Y: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048583 Enhanced Supported Supported "Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" Vesicles "Focal adhesion sites, Cytosol" "HPA048583: AB_2680451" "unprognostic (7.98e-2)" "unprognostic (7.22e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-2)" "unprognostic (3.02e-2)" "unprognostic (3.89e-3)" "unprognostic (2.77e-2)" "unprognostic (6.66e-3)" "unprognostic (1.05e-1)" "unprognostic (3.34e-3)" "unprognostic (9.20e-2)" "unprognostic (4.72e-2)" "unprognostic (3.49e-4)" "unprognostic (5.91e-2)" "unprognostic (1.85e-1)" "unprognostic (1.48e-2)" "unprognostic (9.37e-3)" 3.5 6.9 20.8 1.3 20.4 0.0 0.8 18.5 28.5 4.6 2.5 36.8 3.4 7.8 3.6 11.2 4.1 3.4 0.5 28.4 71.9 0.5 0.0 2.3 0.1 21.8 21.3 7.9 0.2 12.7 2.2 0.1 36.8 22.3 9.6 10.2 0.5 50.9 0.8 0.6 7.2 10.3 15.6 0.8 5.2 1.4 47.5 0.2 0.8 2.5 0.3 9.7 4.4 13.5 0.0 0.0 5.4 0.0 3.9 10.1 0.0 1.1 0.7 0.4 0.2 0.0 0.0 0.0 0.1 3.2 0.0 0.0 3.4 0.0 1.0 0.0 0.2 0.0 0.1 0.0 1.2 0.0 0.0 3.5 0.0 1.9 0.0 7.5 52.5 0.0 0.0 0.1 6.6 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 13.2 0.0 0.0 0.0 1.3 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 20.4 18.5 28.5 28.4 71.9 21.8 21.3 36.8 15.6 47.5 13.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 7.4 0.4 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.2 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 37.5 0.0 0.0 TNK2 "ACK, ACK1, p21cdc42Hs" ENSG00000061938 "Tyrosine kinase non receptor 2" Q07912 3 195863364-195911945 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 102.9" "Cell type enhanced" "Detected in many" "Horizontal cells: 99.3;Oligodendrocyte precursor cells: 245.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041954, HPA069561" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Vesicles "HPA041954: AB_10794164, HPA069561: " "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (1.15e-3)" "prognostic unfavorable (8.96e-4)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (8.89e-3)" "unprognostic (1.13e-1)" "unprognostic (8.92e-3)" "unprognostic (4.49e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (6.82e-2)" "unprognostic (9.76e-2)" "unprognostic (1.44e-1)" "prognostic favorable (1.00e-4)" 14.2 10.0 77.1 24.7 64.1 72.2 15.0 40.0 102.9 18.0 11.8 18.5 9.4 13.8 11.1 19.1 17.1 10.5 18.4 75.6 51.4 7.7 10.5 14.1 30.0 77.5 59.8 13.4 12.1 6.1 36.4 12.7 70.1 21.1 6.3 9.3 26.3 11.8 54.8 62.3 16.1 9.2 45.5 27.0 19.7 12.0 57.0 16.0 10.0 16.7 20.1 19.4 19.3 60.6 93.4 16.3 15.4 13.4 15.3 11.5 80.0 17.7 16.7 11.7 9.4 15.6 79.3 25.9 55.1 24.2 17.4 34.1 14.9 22.2 3.5 61.8 15.4 22.0 36.2 10.4 7.9 13.5 10.2 7.8 30.7 11.7 17.9 26.7 13.3 9.2 11.3 30.6 9.4 67.1 5.3 39.7 12.3 24.6 29.1 13.8 15.6 26.0 7.2 51.2 16.2 16.5 9.5 37.6 21.3 11.3 71.4 11.9 18.9 19.1 13.0 11.4 48.6 70.8 9.2 17.0 22.1 38.0 15.4 1.4 1.2 0.3 0.9 1.5 0.4 1.3 0.8 0.4 0.5 2.5 0.5 0.5 2.7 0.4 1.4 1.5 0.1 0.7 77.1 64.1 40.0 102.9 75.6 51.4 77.5 59.8 70.1 45.5 57.0 60.6 9.3 6.4 7.7 44.4 14.6 6.9 8.1 6.0 4.6 30.6 13.0 12.6 16.1 7.2 8.9 0.0 50.1 13.4 11.0 18.0 1.9 4.0 1.0 4.1 5.4 11.1 6.1 12.8 42.7 5.3 3.3 4.6 14.3 4.1 1.3 4.5 11.7 19.2 8.1 99.3 45.3 2.3 6.1 16.0 11.7 1.2 6.5 13.7 5.4 20.6 16.2 5.9 21.6 245.3 25.1 29.5 9.6 6.4 10.7 8.2 0.9 1.6 7.6 20.3 0.0 4.8 5.7 6.4 11.2 11.0 10.5 4.2 12.5 1.7 6.4 19.0 TNRC6A "CAGH26, GW182, KIAA1460, TNRC6" ENSG00000090905 "Trinucleotide repeat containing adaptor 6A" Q8NDV7 16 24610209-24827632 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" RNA-binding Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 289.3;Excitatory neurons: 283.8;Inhibitory neurons: 414.6;Oligodendrocyte precursor cells: 265.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015305, HPA017869" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA015305: AB_1850454, HPA017869: AB_1850456" "unprognostic (2.64e-1)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.86e-1)" "unprognostic (5.00e-2)" "unprognostic (1.10e-3)" "unprognostic (1.62e-1)" "unprognostic (3.22e-3)" "unprognostic (5.49e-2)" "unprognostic (2.74e-1)" "unprognostic (7.44e-3)" "unprognostic (2.63e-3)" "unprognostic (1.78e-1)" "unprognostic (9.18e-2)" "unprognostic (5.77e-2)" "unprognostic (2.31e-1)" "unprognostic (3.35e-2)" 17.2 21.0 5.0 6.4 3.6 6.0 14.9 10.8 7.1 17.8 6.1 17.8 5.5 23.5 11.5 11.3 17.7 6.4 11.1 3.4 6.6 10.3 13.0 12.8 7.1 6.1 4.8 20.6 19.2 13.2 22.8 6.6 6.1 14.6 6.4 7.0 14.9 8.0 14.0 13.1 15.3 8.1 2.2 9.9 15.2 6.6 7.0 8.6 17.8 6.9 7.4 13.0 13.4 7.4 10.1 13.8 16.0 8.7 13.6 17.7 9.1 16.9 13.6 12.0 13.1 10.2 8.2 10.2 7.1 17.0 12.4 11.2 20.1 14.2 18.0 10.4 10.4 10.2 16.7 14.1 11.7 10.5 6.9 18.0 7.3 15.8 10.2 14.8 16.7 6.6 15.7 6.2 15.8 11.9 8.8 6.9 23.1 4.9 6.8 17.1 12.4 9.1 9.1 9.3 7.7 10.8 11.8 7.2 6.6 12.1 8.4 6.8 15.5 15.3 10.5 7.6 12.0 13.7 11.6 16.5 14.3 6.4 11.3 0.5 0.5 0.4 0.5 0.3 0.4 1.1 0.5 0.5 0.2 1.0 0.7 0.5 0.3 0.6 0.3 1.0 0.5 0.3 5.0 3.6 10.8 7.1 3.4 6.6 6.1 4.8 6.1 2.2 7.0 7.4 51.2 38.5 60.0 289.3 45.5 34.9 17.8 21.9 39.9 97.1 42.8 41.0 75.3 51.5 32.3 46.0 118.9 22.4 49.9 38.3 17.6 23.6 17.2 38.7 65.5 45.5 55.9 34.9 283.8 24.5 15.1 50.5 33.6 42.8 39.3 76.5 60.3 115.3 21.2 176.7 414.6 36.3 22.4 56.2 26.5 11.3 69.0 28.7 30.2 138.7 36.1 42.0 50.4 265.4 234.2 28.5 36.1 81.3 44.7 26.0 42.8 19.2 29.8 81.7 19.7 52.8 60.9 41.2 30.6 38.1 28.7 8.2 39.0 36.5 35.8 17.4 TOR1A "DQ2, DYT1" ENSG00000136827 "Torsin family 1 member A" O14656 9 129812942-129824244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012473, HPA051195" Approved Supported "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA 20000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane, Vesicles" "CAB012473: AB_2240792, HPA051195: AB_2681382" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.65e-1)" "unprognostic (1.18e-1)" "unprognostic (1.95e-1)" "unprognostic (1.86e-3)" "unprognostic (3.67e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.10e-2)" "unprognostic (1.41e-1)" "unprognostic (4.10e-2)" "unprognostic (2.86e-1)" "unprognostic (1.35e-1)" "unprognostic (3.39e-1)" "unprognostic (1.91e-1)" "unprognostic (1.77e-1)" "unprognostic (1.99e-1)" 21.2 24.2 14.3 20.7 14.8 34.5 19.6 14.7 17.7 18.6 14.2 20.7 16.6 20.3 19.9 14.3 17.2 20.6 16.8 15.7 15.9 20.5 35.9 19.4 22.9 13.6 14.0 17.2 19.5 19.4 14.3 23.5 14.0 21.3 22.3 9.8 17.0 23.1 16.4 17.8 18.8 25.4 14.1 18.8 18.1 9.2 15.4 26.3 23.8 14.9 19.0 28.6 15.6 14.8 33.7 49.5 35.9 41.5 53.1 51.3 47.4 76.7 94.5 67.0 57.2 32.3 48.2 41.0 44.0 99.7 46.0 77.2 34.7 50.8 54.7 65.7 32.9 36.9 49.8 32.3 66.9 82.1 65.5 69.8 50.7 63.5 45.6 61.5 73.2 65.3 66.5 32.3 74.6 84.3 58.9 79.3 53.8 39.2 55.6 30.5 56.5 41.9 54.9 42.4 27.0 47.6 79.3 30.7 43.3 40.1 61.6 63.4 65.1 66.1 37.7 49.6 59.6 36.6 87.0 37.7 49.0 46.9 54.3 95.5 72.8 141.3 57.4 68.5 48.1 45.5 48.4 52.1 61.4 33.5 40.9 42.4 72.7 68.6 58.3 56.5 59.1 78.9 14.3 14.8 14.7 17.7 15.7 15.9 13.6 14.0 14.0 14.1 15.4 14.8 25.0 9.6 11.8 5.5 17.5 17.6 16.6 39.5 12.0 11.2 16.5 15.9 9.9 18.6 24.4 14.7 2.1 47.9 39.3 18.7 15.6 42.1 0.7 12.5 18.8 24.2 19.2 30.5 6.3 49.9 65.7 25.0 13.7 15.0 22.2 23.4 16.1 22.7 45.2 21.9 6.4 17.8 26.4 19.1 22.4 1.3 12.8 27.9 14.2 3.7 47.6 18.5 35.0 9.5 6.6 40.1 18.9 15.4 23.7 24.7 21.0 17.0 14.9 9.2 32.9 15.2 24.3 7.3 10.1 9.3 18.5 53.4 25.5 23.4 15.4 19.6 TP53I3 PIG3 ENSG00000115129 "Tumor protein p53 inducible protein 3" Q53FA7 2 24077433-24085861 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 119.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 175.8;Late spermatids: 213.9;Proximal enterocytes: 200.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 6 "T-47d: 599.7" "Low region specificity" "Detected in all" "CAB017479, HPA022012, HPA028742" Enhanced Supported Vesicles NA NA 250000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB017479: AB_2303667, HPA022012: AB_1858202, HPA028742: AB_10603456" "unprognostic (3.66e-2)" "unprognostic (1.41e-3)" "unprognostic (5.55e-2)" "unprognostic (8.04e-2)" "unprognostic (7.10e-3)" "unprognostic (4.47e-1)" "unprognostic (1.09e-2)" "unprognostic (1.53e-3)" "unprognostic (1.17e-1)" "unprognostic (2.83e-2)" "unprognostic (3.52e-2)" "unprognostic (1.75e-1)" "unprognostic (9.89e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-1)" "unprognostic (3.67e-2)" "unprognostic (8.57e-3)" 20.2 24.6 8.6 16.1 9.8 20.0 17.2 8.4 9.6 29.6 11.2 54.4 51.5 17.3 4.5 119.2 16.5 26.3 15.4 7.5 9.0 46.8 15.2 29.9 7.2 9.4 11.1 8.2 40.1 7.0 11.7 10.6 8.5 15.0 40.8 2.0 25.3 11.2 6.2 8.0 69.1 16.9 7.7 11.9 25.3 38.4 13.0 14.2 23.6 5.9 10.1 22.3 63.8 9.7 27.5 86.8 50.6 21.1 38.8 85.3 37.2 27.3 32.3 22.6 31.1 22.1 48.4 3.5 15.0 44.0 6.1 8.0 13.1 46.5 13.8 21.6 2.0 8.7 33.3 57.5 25.2 4.1 15.3 92.3 72.3 60.2 14.7 46.1 102.0 16.3 7.3 23.4 95.5 18.1 5.0 0.6 39.2 30.8 36.0 10.1 45.7 0.9 38.1 41.4 7.2 32.9 35.1 7.8 6.1 40.5 599.7 5.6 80.6 26.9 63.8 18.5 13.7 10.6 7.4 3.0 8.9 0.4 7.0 11.8 19.1 16.9 0.2 12.6 0.2 4.9 0.2 0.6 16.0 5.5 0.1 0.4 4.1 0.3 5.6 7.1 0.5 6.1 8.6 9.8 8.4 9.6 7.5 9.0 9.4 11.1 8.5 7.7 13.0 9.7 19.2 28.9 38.4 3.9 6.8 4.7 24.7 69.7 6.8 0.8 25.8 33.0 9.0 50.1 51.9 42.3 0.0 41.9 1.1 175.8 109.5 93.5 127.8 50.4 47.4 20.3 79.4 7.2 0.4 134.7 31.9 30.6 83.6 68.2 12.7 85.8 23.9 12.9 45.0 0.0 0.4 63.9 57.0 22.9 11.1 213.9 7.8 20.9 14.2 4.7 23.9 9.5 0.0 5.0 0.3 91.1 138.5 9.1 8.0 11.4 200.9 104.7 19.2 1.9 19.7 14.1 36.8 56.6 14.3 38.8 7.0 28.9 3.4 16.2 75.2 49.9 TRAF7 "DKFZp586I021, MGC7807, RFWD1, RNF119" ENSG00000131653 "TNF receptor associated factor 7" Q6Q0C0 16 2155698-2178129 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041229 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Vesicles "Plasma membrane" "HPA041229: AB_10794194" "unprognostic (1.94e-1)" "unprognostic (5.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (2.77e-3)" "unprognostic (7.08e-2)" "unprognostic (3.52e-2)" "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (9.23e-2)" "unprognostic (6.07e-2)" "unprognostic (2.99e-2)" "unprognostic (2.43e-1)" "unprognostic (8.48e-2)" 29.1 29.4 16.5 24.4 15.1 35.0 28.2 18.2 23.0 32.1 17.0 38.0 40.0 31.2 11.6 54.6 30.4 22.2 21.3 17.9 14.6 28.1 51.5 33.2 22.9 17.8 15.3 23.5 37.4 14.6 32.1 20.6 14.8 27.0 17.4 8.5 34.7 16.5 30.4 47.7 35.2 18.8 14.2 34.5 35.6 14.8 17.7 19.1 25.6 9.9 18.6 34.5 34.8 14.3 57.7 72.2 40.3 72.5 40.8 76.5 47.4 43.4 53.9 49.9 44.6 88.2 72.1 36.6 50.2 55.4 31.8 65.9 38.1 76.8 18.8 58.3 48.8 52.4 98.5 68.3 53.8 56.3 72.7 76.2 62.8 48.1 62.6 41.0 97.4 70.6 57.1 47.9 48.2 131.1 58.3 65.2 79.7 78.7 34.8 107.4 66.7 74.2 40.2 30.4 80.9 67.2 36.3 68.5 48.6 20.9 78.1 68.2 74.3 60.2 83.9 56.7 48.2 69.2 55.0 48.4 34.4 35.9 47.8 4.0 9.1 7.3 4.5 12.4 4.3 5.5 4.4 4.7 11.2 3.9 3.1 3.8 6.2 2.9 8.9 5.3 6.5 5.3 16.5 15.1 18.2 23.0 17.9 14.6 17.8 15.3 14.8 14.2 17.7 14.3 18.9 0.0 9.2 12.4 18.2 28.8 21.1 34.2 22.8 15.9 31.6 27.9 4.9 21.5 20.8 14.7 6.2 23.5 17.4 56.4 17.6 39.0 5.0 23.6 34.6 26.5 34.0 33.6 8.9 59.0 36.3 19.0 38.7 27.9 9.5 22.1 26.0 32.3 42.2 37.0 8.2 38.7 34.6 41.8 21.3 13.1 24.8 26.8 10.6 8.4 33.9 12.6 6.2 6.6 4.9 53.0 43.6 22.2 24.0 33.8 80.0 29.2 19.7 10.9 6.6 11.9 18.3 8.5 25.3 50.7 32.5 26.7 16.0 29.0 42.5 38.5 TRIM8 "GERP, RNF27" ENSG00000171206 "Tripartite motif containing 8" Q9BZR9 10 102644479-102658318 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023560, HPA023561" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Vesicles, Cytosol" "HPA023560: AB_10600414, HPA023561: AB_10601861" "unprognostic (4.32e-2)" "unprognostic (6.90e-2)" "unprognostic (3.02e-3)" "unprognostic (1.45e-1)" "unprognostic (1.78e-1)" "unprognostic (5.03e-1)" "unprognostic (3.82e-2)" "unprognostic (1.03e-1)" "unprognostic (2.15e-3)" "unprognostic (4.62e-2)" "unprognostic (5.41e-2)" "unprognostic (1.52e-1)" "unprognostic (9.55e-2)" "unprognostic (1.48e-1)" "unprognostic (3.12e-2)" "unprognostic (8.34e-2)" "unprognostic (1.36e-2)" 80.1 47.6 67.2 21.5 68.1 26.0 58.4 62.9 55.0 63.0 35.8 50.9 17.8 53.5 9.3 42.0 55.6 22.0 67.8 55.0 56.5 77.9 62.2 70.3 18.3 72.4 72.7 45.2 80.4 36.6 43.5 21.3 64.7 55.5 9.5 18.1 69.1 21.9 80.8 48.3 43.8 17.1 60.4 42.8 61.9 20.1 84.4 18.7 67.4 38.8 11.8 62.9 49.9 54.2 96.4 18.7 16.3 28.7 17.2 40.6 21.1 34.4 59.3 32.1 24.6 30.7 93.0 30.7 102.9 57.5 11.4 32.7 12.2 40.4 21.3 34.4 23.4 78.3 12.9 67.4 55.8 15.5 28.3 47.0 21.9 64.8 32.9 83.4 40.6 13.6 17.3 33.4 24.3 45.5 27.8 57.7 12.7 25.6 38.0 18.6 49.2 16.6 37.4 48.0 12.3 26.2 18.8 17.2 42.6 16.9 58.4 28.2 94.8 40.9 22.4 23.3 68.8 49.0 28.5 16.3 65.5 39.2 9.7 14.0 5.2 2.7 6.8 4.6 6.5 8.9 7.3 5.4 4.5 7.4 6.4 5.7 17.9 6.0 5.7 12.4 7.5 4.5 67.2 68.1 62.9 55.0 55.0 56.5 72.4 72.7 64.7 60.4 84.4 54.2 46.0 57.7 71.2 33.6 29.5 31.5 12.6 21.2 21.6 33.4 53.9 45.3 38.0 38.6 33.6 88.3 8.4 13.0 52.8 15.4 41.1 63.2 1.1 91.5 61.7 30.1 21.6 2.5 8.9 44.9 2.6 38.9 20.4 81.6 8.8 32.2 31.8 33.3 25.4 28.6 13.6 32.8 18.3 40.5 24.1 1.7 31.1 43.5 17.8 13.1 58.1 26.1 24.7 18.1 17.6 65.0 16.4 34.3 18.6 30.5 32.0 53.0 38.5 15.1 13.1 35.7 38.4 2.4 5.1 19.8 22.9 10.9 26.6 38.9 21.4 30.1 TRIP10 "CIP4, HSTP, STOT, STP" ENSG00000125733 "Thyroid hormone receptor interactor 10" Q15642 19 6737925-6751530 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 362.8" "Cell type enhanced" "Detected in many" "monocytes: 196.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 26.4" "Lineage enriched" "Detected in many" 10 "dendritic cells: 26.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041934, HPA072625, HPA073886" Approved Supported Nucleoplasm,Vesicles NA NA 24000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 3: Monocytes - Immune response regulation" Vesicles Nucleoplasm "HPA041934: AB_2677754, HPA072625: AB_2732206, HPA073886: AB_2732244" "unprognostic (5.75e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.19e-2)" "unprognostic (6.57e-2)" "prognostic favorable (1.76e-4)" "unprognostic (6.73e-3)" "unprognostic (1.10e-3)" "unprognostic (1.51e-1)" "unprognostic (3.41e-1)" "unprognostic (7.87e-3)" "unprognostic (3.28e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (1.14e-2)" "unprognostic (1.42e-1)" "unprognostic (8.93e-2)" "unprognostic (8.83e-2)" 110.7 60.3 15.5 25.5 15.6 8.6 92.3 15.3 17.8 123.9 18.6 112.1 30.5 66.5 17.5 253.3 80.1 27.6 125.7 14.6 16.7 81.7 27.0 115.4 14.5 17.5 16.5 99.4 44.7 18.6 22.4 48.6 16.0 80.4 19.9 16.9 85.4 45.0 362.8 57.8 56.0 26.4 15.8 40.0 58.6 29.9 17.5 9.6 75.5 177.3 21.9 86.7 147.4 14.8 83.5 49.7 17.1 25.8 64.7 67.9 61.1 52.5 60.0 58.8 51.1 67.8 46.7 1.8 69.2 44.6 47.6 60.2 38.8 76.5 34.7 52.5 15.5 27.0 48.4 52.3 53.4 1.4 8.3 79.0 50.9 52.5 39.8 77.2 61.2 3.7 40.2 22.1 43.7 28.3 7.5 18.7 36.3 51.9 41.7 12.2 35.1 24.5 50.0 40.9 0.1 19.6 69.1 30.7 20.0 39.4 32.2 14.7 120.5 39.3 70.4 103.8 56.4 23.1 13.4 8.4 63.6 7.9 26.2 0.0 0.8 0.0 0.6 0.1 0.9 1.5 0.3 1.1 5.2 1.7 0.3 0.2 0.1 2.5 0.1 26.4 0.0 0.5 15.5 15.6 15.3 17.8 14.6 16.7 17.5 16.5 16.0 15.8 17.5 14.8 43.0 28.9 19.8 6.5 5.6 85.4 104.9 76.9 43.9 14.7 28.3 16.6 8.7 20.0 66.9 16.5 37.5 9.9 16.5 39.1 5.9 45.0 16.4 30.3 32.1 43.1 7.7 4.4 0.1 38.0 37.9 66.3 10.7 55.7 29.7 8.8 38.9 3.7 9.6 0.0 0.2 16.3 24.4 6.7 90.4 13.6 55.9 19.6 37.4 3.7 196.9 12.5 0.0 5.5 0.4 91.5 24.7 36.1 9.0 116.6 25.8 23.8 24.8 18.5 32.9 26.4 46.4 5.7 6.9 51.3 83.3 14.2 7.4 24.5 25.9 120.7 TSPAN14 "DC-TM4F2, MGC11352, TM4SF14" ENSG00000108219 "Tetraspanin 14" Q8NG11 10 80454166-80533124 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 156.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 276.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014773, HPA057174" Uncertain Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA014773: AB_2208670, HPA057174: " "unprognostic (7.52e-2)" "prognostic favorable (3.56e-4)" "unprognostic (6.55e-3)" "unprognostic (1.56e-1)" "unprognostic (4.40e-2)" "unprognostic (1.18e-1)" "unprognostic (2.11e-2)" "unprognostic (8.90e-2)" "unprognostic (5.21e-2)" "unprognostic (3.13e-1)" "unprognostic (5.15e-3)" "unprognostic (4.12e-3)" "prognostic favorable (4.20e-4)" "unprognostic (2.52e-2)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "unprognostic (2.57e-3)" 97.9 20.7 29.1 43.1 24.2 57.2 80.1 25.1 29.7 63.1 19.4 33.4 30.9 38.4 44.1 92.1 47.1 32.9 51.2 26.2 21.4 45.7 21.1 70.8 54.2 31.7 32.2 47.2 33.1 35.7 15.7 81.9 29.7 34.8 27.1 7.9 47.7 34.1 24.9 74.3 34.8 33.3 31.2 48.5 24.7 23.2 32.8 40.1 46.5 42.1 44.6 55.0 56.1 31.4 96.2 135.6 128.3 44.5 186.6 59.3 59.6 49.3 91.8 51.1 38.0 134.8 54.6 31.5 93.2 26.4 18.9 97.0 35.9 88.5 41.4 55.9 13.9 88.9 15.8 118.2 63.5 31.8 20.3 58.8 77.2 52.8 92.1 94.8 191.5 31.8 48.8 23.0 15.0 83.3 50.0 23.3 29.5 61.2 0.1 167.9 14.9 5.3 203.9 131.9 27.5 42.3 19.7 133.7 149.5 43.7 54.1 79.8 276.3 13.0 52.8 12.4 35.1 10.7 42.0 11.8 42.2 65.4 57.5 16.2 51.5 56.3 92.1 102.1 41.3 13.8 70.7 81.1 33.9 13.7 82.3 79.3 54.7 95.2 172.8 13.6 61.8 84.3 29.1 24.2 25.1 29.7 26.2 21.4 31.7 32.2 29.7 31.2 32.8 31.4 141.9 16.0 55.1 13.1 18.5 34.9 40.3 54.6 35.3 2.1 29.5 23.2 11.3 25.8 39.0 33.1 77.2 7.8 38.4 32.8 7.9 43.8 2.4 44.7 38.9 95.3 64.2 35.6 12.9 24.8 74.4 18.8 18.3 75.1 7.6 41.2 156.7 21.1 50.5 3.3 7.4 37.0 34.6 129.3 12.9 4.1 39.1 66.5 14.2 35.6 51.8 23.7 89.6 4.5 13.5 64.2 21.6 41.0 18.4 55.7 23.4 8.0 29.6 7.1 98.6 10.2 43.1 5.0 19.0 80.2 36.4 7.7 55.7 10.4 30.6 69.7 UBAP1 UBAP ENSG00000165006 "Ubiquitin associated protein 1" Q9NZ09 9 34179005-34252523 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019804 Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "Vesicles, Plasma membrane" "HPA019804: AB_1858494" "unprognostic (1.83e-1)" "unprognostic (4.30e-2)" "unprognostic (1.29e-1)" "unprognostic (1.70e-1)" "unprognostic (3.54e-1)" "unprognostic (3.29e-2)" "unprognostic (1.67e-1)" "unprognostic (1.59e-1)" "unprognostic (2.01e-2)" "unprognostic (6.53e-2)" "unprognostic (1.25e-2)" "unprognostic (3.63e-1)" "prognostic favorable (7.49e-6)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (1.17e-1)" 40.7 55.5 46.4 24.5 47.1 131.5 35.8 48.0 53.4 45.0 46.4 38.5 22.3 34.0 25.5 69.7 33.9 30.4 38.2 45.6 48.2 34.8 53.1 42.5 23.8 48.5 48.5 40.9 28.0 34.4 25.6 29.3 49.4 30.4 24.8 44.8 29.6 30.6 110.0 39.5 26.3 35.2 46.3 28.2 33.6 47.8 49.9 31.6 25.6 71.7 32.7 38.0 45.8 48.2 56.7 31.7 35.2 38.4 63.6 39.3 29.8 44.4 61.6 48.4 65.6 34.3 23.0 39.3 19.5 66.5 41.1 28.3 49.2 69.5 46.4 57.1 22.3 35.1 65.4 35.5 57.8 39.3 44.8 48.7 113.0 57.5 75.0 73.4 54.4 37.9 27.4 38.0 45.7 23.7 36.5 55.0 38.2 38.8 45.9 32.6 24.8 22.8 104.2 36.9 19.9 28.1 49.0 50.2 22.5 31.1 24.6 38.5 39.2 24.7 38.0 37.4 41.5 18.9 25.3 41.0 49.5 31.5 74.2 26.8 50.9 66.6 38.0 45.2 65.8 26.8 38.1 40.0 47.1 23.2 36.3 29.8 120.2 50.1 41.0 26.7 52.9 55.0 46.4 47.1 48.0 53.4 45.6 48.2 48.5 48.5 49.4 46.3 49.9 48.2 21.6 67.3 26.0 44.4 22.4 46.9 66.3 20.4 45.5 15.8 27.9 23.1 13.1 20.0 33.5 7.3 25.0 33.2 21.6 25.8 19.6 34.8 77.5 56.9 37.2 21.4 16.1 50.7 33.1 40.1 35.4 31.2 44.4 90.0 25.9 15.4 17.5 25.3 22.0 6.7 42.9 18.5 30.5 21.4 39.8 62.9 29.2 38.2 24.9 26.2 23.1 26.0 13.4 38.7 35.4 44.3 23.0 42.5 25.0 47.9 22.5 21.0 22.5 10.9 19.7 44.0 32.5 51.0 22.9 54.6 59.0 89.6 28.6 20.8 18.8 70.9 UBE2A "HHR6A, HR6A, RAD6A, UBC2" ENSG00000077721 "Ubiquitin conjugating enzyme E2 A" P49459 X 119574536-119591083 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 508.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (2.27e-3)" "prognostic favorable (2.16e-4)" "unprognostic (1.12e-1)" "unprognostic (9.09e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.07e-4)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (6.54e-2)" "unprognostic (2.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.21e-1)" "unprognostic (7.92e-2)" 40.0 27.4 30.1 39.1 30.6 29.8 29.4 34.1 38.8 34.1 27.1 52.3 37.5 32.0 38.2 53.4 27.3 32.6 63.2 29.6 32.2 41.0 30.1 32.9 46.9 34.4 32.5 20.1 29.2 39.2 18.9 56.8 34.4 31.0 45.0 27.1 30.9 33.0 71.9 30.7 39.1 43.0 32.1 26.8 30.5 17.6 32.1 46.1 30.5 55.0 50.4 46.9 32.8 35.1 129.5 104.1 60.8 54.1 103.0 125.6 63.9 122.6 106.3 141.8 130.3 50.8 84.0 96.4 126.4 133.9 240.6 86.4 86.3 65.7 128.6 142.3 60.6 42.7 71.9 47.1 96.6 105.9 72.1 86.9 90.1 134.0 58.3 98.1 99.4 86.5 57.0 83.6 160.1 134.5 166.6 99.9 106.3 125.7 126.9 84.2 64.0 91.6 113.1 76.6 48.9 51.3 171.2 75.0 93.7 73.2 65.8 92.6 101.5 92.4 42.0 184.3 142.5 83.6 147.1 92.4 99.1 136.3 74.6 46.8 58.5 92.5 43.0 92.1 34.8 52.6 37.9 38.5 74.6 48.7 23.7 33.9 78.0 35.0 101.1 58.5 56.8 51.1 30.1 30.6 34.1 38.8 29.6 32.2 34.4 32.5 34.4 32.1 32.1 35.1 67.5 102.5 40.9 12.7 79.1 124.8 91.6 129.4 51.8 17.2 60.7 43.9 66.7 44.3 80.7 40.5 31.3 179.8 93.0 168.6 101.8 95.4 51.7 75.6 55.3 62.9 45.5 70.4 9.9 102.1 176.2 67.7 37.8 63.0 57.0 35.7 46.4 35.5 131.3 8.4 9.4 49.7 103.7 59.1 183.9 15.3 37.0 97.3 83.6 15.9 129.0 49.8 41.2 14.6 18.0 137.6 132.5 40.6 92.2 98.2 85.6 125.2 107.7 35.0 46.0 56.3 101.1 44.1 32.1 74.6 127.9 508.5 94.8 36.6 54.5 120.3 UBE2B "HHR6B, RAD6B, UBC2" ENSG00000119048 "Ubiquitin conjugating enzyme E2 B" P63146 5 134371469-134392108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 265.8" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 723.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 444.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 444.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (7.39e-2)" "unprognostic (6.66e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-1)" "unprognostic (2.49e-1)" "unprognostic (8.39e-2)" "unprognostic (1.64e-3)" "unprognostic (6.30e-3)" "unprognostic (3.42e-2)" "unprognostic (2.04e-1)" "unprognostic (5.52e-2)" 52.5 74.2 31.5 50.0 33.1 84.4 44.2 36.3 53.2 38.3 30.2 48.0 40.7 53.6 34.8 70.5 37.3 51.0 118.4 34.3 34.8 50.6 56.6 44.9 47.1 29.5 31.0 44.4 53.7 25.8 39.9 48.4 31.0 32.9 42.0 29.2 39.7 23.2 265.8 43.1 46.4 43.3 30.3 43.7 39.6 49.2 32.9 29.3 41.2 99.8 48.1 42.8 43.2 36.7 109.4 27.9 58.2 55.0 50.0 54.1 92.7 80.2 43.5 51.4 60.9 85.6 70.9 58.7 94.1 52.3 138.7 42.7 45.8 60.4 56.0 94.5 47.6 32.1 75.9 92.8 58.2 38.8 63.7 46.5 80.2 47.4 39.3 68.1 44.1 48.8 61.1 103.5 46.8 63.4 62.5 102.1 24.9 32.6 26.7 61.6 63.8 83.8 46.6 82.9 77.6 60.1 62.9 29.3 147.9 62.5 63.0 106.0 87.6 57.8 40.8 78.9 89.4 86.1 129.4 87.0 65.2 72.8 59.4 236.7 58.3 174.0 46.9 68.3 42.9 49.7 58.8 48.1 42.6 47.9 69.9 60.6 444.6 53.0 78.9 48.0 77.5 64.1 31.5 33.1 36.3 53.2 34.3 34.8 29.5 31.0 31.0 30.3 32.9 36.7 187.5 73.7 61.6 40.1 176.5 364.7 321.2 215.1 175.8 77.8 169.9 156.5 315.8 147.3 113.7 75.4 81.3 144.5 182.0 183.1 172.1 173.8 233.2 139.8 102.2 149.7 131.8 261.2 103.0 169.5 123.0 183.3 113.2 167.8 116.8 81.7 115.3 97.4 119.4 87.5 84.2 141.0 181.0 131.5 323.9 315.4 155.0 184.2 227.7 49.6 190.6 150.0 113.3 44.7 68.4 210.6 195.2 113.2 162.5 343.9 153.4 170.7 111.7 91.3 151.2 154.9 262.9 223.5 201.7 145.5 369.7 723.5 192.0 140.4 105.7 488.1 UGT1A6 "GNT1, HLUGP, UGT1F" ENSG00000167165 "UDP glucuronosyltransferase family 1 member A6" P19224 2 233691607-233773300 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 71.3;liver: 143.3;urinary bladder: 88.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 12.5;Early spermatids: 52.4;Gastric mucus-secreting cells: 14.3;Late spermatids: 23.3;Squamous epithelial cells: 17.3" "Group enriched" "Detected in many" 5 "liver cancer: 7.2;lung cancer: 3.1;renal cancer: 7.6;urothelial cancer: 3.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 1194.0" "Not detected" "Not detected" "CAB009819, HPA054065, HPA056023" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" Vesicles "Endoplasmic reticulum" "CAB009819: AB_2241481, HPA054065: AB_2682367, HPA056023: " "unprognostic (9.09e-2)" "unprognostic (6.07e-2)" "unprognostic (5.43e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.79e-1)" "unprognostic (6.18e-2)" "unprognostic (2.09e-3)" "unprognostic (9.97e-2)" "unprognostic (2.16e-2)" "unprognostic (3.52e-1)" "unprognostic (7.50e-2)" "unprognostic (2.01e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 1.8 0.0 1.8 5.8 0.1 2.6 16.1 0.0 3.5 0.0 0.0 0.0 71.3 143.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.1 1.3 0.0 2.6 3.6 0.0 11.1 2.6 0.0 0.0 0.0 17.4 0.4 0.0 1.2 0.5 0.0 5.8 88.8 5.5 0.0 4.2 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 53.8 1.6 0.0 80.2 0.1 0.8 294.5 0.1 4.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.3 0.0 31.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 6.2 0.0 0.0 0.0 1194.0 0.0 0.1 0.2 0.1 3.2 149.0 0.0 0.0 7.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 1.2 12.5 0.0 0.0 0.0 0.3 0.0 2.9 1.8 0.0 0.0 0.0 0.4 0.0 0.0 52.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 14.3 0.5 0.0 0.0 0.4 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 23.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.5 1.8 0.1 0.0 0.0 0.0 0.0 1.2 0.2 17.3 1.1 0.0 0.0 0.0 0.1 3.0 UHRF1BP1L KIAA0701 ENSG00000111647 "UHRF1 binding protein 1 like" A0JNW5 12 100028455-100142874 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039671, HPA075150" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Vesicles, Cytosol" "HPA039671: AB_10794201, HPA075150: " "unprognostic (4.80e-2)" "unprognostic (3.17e-1)" "unprognostic (2.34e-2)" "unprognostic (1.14e-1)" "unprognostic (8.96e-2)" "unprognostic (7.36e-2)" "unprognostic (8.10e-2)" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (5.43e-2)" "unprognostic (1.88e-2)" "unprognostic (2.53e-1)" "unprognostic (2.94e-3)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (3.81e-2)" "unprognostic (1.28e-2)" 8.7 10.9 6.2 10.2 7.7 32.9 8.8 11.0 11.5 7.2 9.9 8.3 8.4 7.5 7.0 7.0 6.3 8.9 7.9 13.2 6.2 12.3 24.6 7.7 9.2 4.9 5.4 7.5 3.8 13.6 5.2 9.0 4.8 9.0 7.9 14.6 6.4 8.0 19.8 5.9 7.1 8.8 4.6 9.2 6.0 14.0 3.7 8.4 10.9 14.6 7.0 10.1 5.2 9.2 18.6 19.7 10.8 11.2 16.4 23.1 21.6 28.3 28.4 22.4 16.3 14.8 6.2 16.0 7.2 29.1 13.1 6.9 20.4 9.7 21.5 42.7 10.0 10.7 14.1 17.3 15.1 20.4 16.8 13.1 8.0 27.0 18.6 20.7 16.0 11.0 8.6 16.2 22.1 10.3 13.1 17.5 18.7 6.3 17.7 14.7 19.2 15.7 11.4 32.2 18.3 11.4 21.4 24.5 8.5 9.2 21.9 23.0 12.7 24.6 13.2 21.5 20.1 19.1 35.2 22.3 12.4 15.1 15.2 21.6 11.4 7.8 3.6 12.3 5.3 5.5 4.0 4.1 12.8 4.5 3.4 4.2 33.9 5.9 10.9 7.6 5.2 5.4 6.2 7.7 11.0 11.5 13.2 6.2 4.9 5.4 4.8 4.6 3.7 9.2 10.6 28.9 8.7 27.1 18.2 12.7 17.2 5.0 19.9 11.9 9.3 7.5 15.7 1.5 12.6 9.2 4.2 4.7 15.0 10.9 5.9 6.0 35.1 15.7 23.7 8.6 5.4 9.4 75.2 5.9 8.9 24.7 7.7 9.9 24.1 6.3 5.3 18.5 11.2 15.2 54.2 2.1 4.1 23.3 21.4 5.3 7.2 29.5 10.6 45.0 25.7 8.3 8.2 37.2 29.5 5.9 7.4 7.9 12.5 18.5 8.9 14.9 21.8 12.0 0.0 23.3 15.1 24.1 19.1 14.9 11.6 10.9 15.7 8.3 5.7 11.9 UNC13D Munc13-4 ENSG00000092929 "Unc-13 homolog D" Q70J99 17 75827225-75844552 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Exocytosis "Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.9;lymphoid tissue: 66.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 68.3;Hofbauer cells: 58.5;NK-cells: 61.8;Pancreatic endocrine cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 245.7;HeLa: 136.3;HMC-1: 245.9;SK-BR-3: 189.7" "Region enriched" "Detected in single" 6 "cerebellum: 5.0" "Low region specificity" "Detected in many" "HPA067117, HPA073525" Enhanced Supported Vesicles,Cytosol NA NA 1500000 "Cluster 38: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol Vesicles "HPA067117: AB_2685784, HPA073525: AB_2686615" "unprognostic (6.79e-3)" "unprognostic (4.36e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (2.98e-2)" "unprognostic (1.42e-3)" "unprognostic (3.93e-1)" "unprognostic (1.37e-2)" "unprognostic (2.74e-1)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (1.89e-1)" "prognostic unfavorable (5.28e-12)" "unprognostic (3.27e-2)" "unprognostic (5.58e-2)" "unprognostic (1.56e-1)" "unprognostic (8.59e-2)" 7.7 7.3 5.6 23.5 6.8 58.9 7.8 5.8 7.3 18.6 5.0 10.7 8.0 8.6 2.0 23.6 13.8 6.5 14.3 5.0 5.6 6.6 12.6 38.1 25.9 7.9 6.5 19.3 8.8 0.5 11.6 9.0 7.5 8.1 4.5 5.5 7.7 5.1 8.5 6.0 18.5 4.9 6.2 66.2 13.8 6.1 8.2 20.7 5.9 1.5 17.6 10.7 19.6 8.7 44.0 18.7 0.4 0.3 0.5 1.0 47.6 0.1 0.0 0.0 0.1 41.4 97.0 3.4 46.4 0.0 7.5 15.4 0.0 2.2 0.0 0.4 0.5 245.7 136.3 24.2 3.9 94.1 245.9 0.6 2.0 0.5 2.1 2.3 17.9 42.5 87.1 1.1 0.0 71.2 100.9 50.8 0.9 69.9 1.7 32.8 1.0 1.5 1.6 17.7 0.3 66.7 19.2 189.7 0.9 0.5 47.1 56.5 48.1 0.8 65.9 0.5 0.5 1.3 5.9 4.0 0.6 31.3 0.2 59.1 16.0 31.2 19.3 16.9 17.4 6.7 11.4 13.6 12.3 3.6 8.8 11.9 40.1 14.7 25.6 7.2 10.8 18.1 5.6 6.8 5.8 7.3 5.0 5.6 7.9 6.5 7.5 6.2 8.2 8.7 3.8 44.8 8.3 6.8 16.6 1.1 1.7 1.0 0.6 12.0 4.9 2.4 68.3 7.2 4.4 3.7 20.9 4.7 27.0 40.9 0.0 7.2 5.3 1.3 3.3 6.6 6.0 14.9 1.2 6.0 11.6 2.2 2.0 2.3 45.0 9.9 7.9 1.2 58.5 5.0 1.5 3.6 2.0 21.6 8.2 0.5 2.8 22.2 1.8 5.6 22.5 4.5 61.8 3.0 7.9 47.3 30.7 1.5 27.4 1.6 5.5 0.7 1.6 16.2 0.0 4.5 2.6 1.2 1.4 1.5 1.4 25.9 30.9 2.0 6.3 2.3 VAMP7 "SYBL1, TI-VAMP, VAMP-7" ENSG00000124333 "Vesicle associated membrane protein 7" P51809 X 155881345-155943769 "Predicted intracellular proteins, Predicted membrane proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036733 Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA036733: AB_10672228" "unprognostic (7.54e-3)" "unprognostic (1.35e-2)" "unprognostic (2.07e-1)" "unprognostic (1.04e-1)" "unprognostic (6.15e-3)" "unprognostic (2.70e-2)" "unprognostic (5.77e-2)" "unprognostic (7.95e-2)" "unprognostic (7.18e-2)" "unprognostic (3.38e-3)" "unprognostic (1.02e-1)" "unprognostic (1.15e-1)" "prognostic favorable (2.83e-4)" "unprognostic (1.29e-1)" "unprognostic (3.42e-1)" "unprognostic (2.47e-1)" "unprognostic (2.97e-1)" 29.4 24.3 17.8 24.1 20.6 37.1 23.8 22.3 24.9 23.2 18.3 22.9 23.4 21.4 15.5 22.6 16.5 22.2 19.6 18.1 21.4 39.2 47.9 24.8 26.4 20.7 20.5 17.9 14.3 32.3 8.7 40.5 21.5 21.4 24.4 10.3 17.3 20.1 21.9 20.1 27.5 28.2 20.4 21.8 18.4 14.9 19.9 29.9 24.4 24.1 28.6 25.6 15.9 23.0 72.9 31.3 21.0 43.6 57.0 54.3 56.3 55.3 49.1 49.0 98.4 33.8 46.5 100.6 100.0 66.9 55.5 25.5 47.6 38.9 64.5 42.3 41.6 41.8 43.1 24.3 63.6 86.9 62.8 50.9 37.9 54.8 49.8 42.8 55.4 43.5 91.1 54.2 56.0 36.5 34.1 48.8 15.0 54.1 45.3 25.5 41.2 75.3 65.6 36.2 16.0 46.0 32.7 32.6 49.6 54.8 31.9 71.8 58.4 44.8 46.7 65.0 79.6 123.8 167.8 138.9 39.2 104.4 51.0 86.8 25.3 39.6 15.1 27.0 19.1 12.3 17.7 18.6 26.4 13.2 16.2 17.5 21.9 22.7 26.7 15.0 22.0 22.4 17.8 20.6 22.3 24.9 18.1 21.4 20.7 20.5 21.5 20.4 19.9 23.0 17.8 3.2 9.2 11.1 21.2 19.6 14.7 11.8 20.5 7.6 16.6 9.5 12.3 5.7 12.5 7.3 6.2 48.4 24.9 14.1 41.1 28.0 6.9 13.8 14.5 19.8 13.2 31.4 14.2 26.0 49.7 19.6 12.2 13.7 31.1 22.5 20.3 25.1 31.1 6.7 14.6 12.8 10.2 30.8 49.0 6.9 17.7 35.9 19.6 7.5 32.5 10.4 29.9 8.0 19.2 29.9 13.5 19.5 15.2 17.5 25.3 52.9 10.5 4.6 26.3 10.8 18.9 45.4 26.3 20.3 19.5 69.8 21.6 25.3 15.3 20.1 VBP1 "PFD3, PFDN3" ENSG00000155959 "VHL binding protein 1" P61758 X 155197007-155239841 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006260, HPA023230" Approved Supported Vesicles,Cytosol NA NA 15000 "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Vesicles "CAB006260: AB_425740, HPA023230: AB_1858727" "unprognostic (1.55e-3)" "unprognostic (1.12e-3)" "unprognostic (3.35e-1)" "unprognostic (1.35e-2)" "unprognostic (3.78e-2)" "unprognostic (1.85e-3)" "unprognostic (5.31e-3)" "unprognostic (1.40e-1)" "unprognostic (2.44e-2)" "unprognostic (1.02e-2)" "unprognostic (9.80e-2)" "unprognostic (1.15e-1)" "unprognostic (5.76e-2)" "unprognostic (3.76e-2)" "unprognostic (4.54e-2)" "unprognostic (9.30e-2)" "unprognostic (3.80e-1)" 32.1 32.5 48.6 29.4 50.2 50.5 31.6 54.6 60.5 24.2 43.6 30.1 23.0 25.2 26.6 31.0 23.5 21.1 65.7 49.5 53.7 40.4 31.2 23.3 41.3 52.7 52.8 25.5 19.7 38.2 29.7 30.2 53.4 30.9 33.0 48.2 20.6 25.4 101.5 19.3 24.3 28.9 54.6 24.8 22.6 15.9 51.9 45.8 31.6 121.2 40.4 32.2 19.9 60.1 162.8 57.6 122.1 81.1 49.6 68.0 35.2 78.8 60.7 99.7 155.3 69.1 80.8 207.1 163.6 66.8 154.1 62.4 179.3 74.0 129.5 110.0 123.9 87.6 86.0 54.2 58.9 142.6 65.5 51.0 84.7 84.7 105.6 53.1 93.7 101.0 173.4 119.9 113.6 67.7 134.3 120.9 71.0 149.1 122.1 114.0 97.0 121.4 86.8 73.0 132.0 80.0 54.1 62.7 90.1 83.4 53.8 107.5 55.6 80.5 100.0 138.3 198.0 133.9 209.0 361.3 71.6 173.1 101.0 22.5 23.0 75.8 26.3 25.1 30.2 28.6 30.5 31.7 36.2 23.7 34.5 37.5 26.3 28.2 21.9 29.5 43.2 33.0 48.6 50.2 54.6 60.5 49.5 53.7 52.7 52.8 53.4 54.6 51.9 60.1 40.7 51.3 29.1 12.1 55.1 57.4 81.2 89.9 33.6 54.9 33.2 30.2 80.5 30.0 48.0 38.6 20.9 73.7 60.4 27.9 191.7 65.8 2.5 32.8 41.3 47.3 23.4 128.6 12.7 57.6 101.4 52.6 28.5 28.9 47.5 36.6 30.7 24.9 67.6 32.0 14.2 30.0 75.3 29.5 64.4 4.6 42.0 40.7 46.2 6.5 80.1 78.7 47.4 6.6 21.3 52.7 43.1 39.9 56.8 78.0 29.3 126.3 37.2 46.3 46.0 45.1 52.8 80.7 88.2 37.1 52.6 68.7 60.0 81.6 45.9 63.0 VPS25 "DERP9, EAP20, MGC10540" ENSG00000131475 "Vacuolar protein sorting 25 homolog" Q9BRG1 17 42773449-42779599 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004978, HPA021992, HPA052217, HPA057284" Uncertain Supported Vesicles NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB004978: AB_426095, HPA021992: , HPA052217: AB_2681765, HPA057284: AB_2683397" "unprognostic (3.63e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.18e-4)" "unprognostic (7.37e-2)" "unprognostic (7.57e-2)" "unprognostic (9.83e-3)" "unprognostic (2.76e-3)" "unprognostic (5.84e-2)" "unprognostic (1.25e-1)" "unprognostic (2.90e-1)" "unprognostic (8.10e-3)" "unprognostic (3.88e-1)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.91e-2)" 36.6 40.3 32.8 32.5 33.0 44.3 53.3 34.8 36.8 41.6 36.6 61.9 53.8 35.5 65.3 91.4 58.9 33.4 43.5 32.9 33.2 70.1 68.6 31.8 37.8 32.9 32.8 33.2 49.0 72.3 27.6 46.7 33.5 40.2 68.4 31.2 48.7 36.5 51.3 50.5 45.4 42.8 33.5 37.1 50.0 27.4 33.8 51.3 40.9 41.3 57.2 44.8 44.3 34.0 67.2 136.6 101.8 62.1 126.9 86.5 94.5 83.0 117.1 167.5 116.3 117.9 77.0 66.8 135.8 122.0 88.5 68.7 142.2 181.8 107.9 61.2 178.7 50.6 87.0 177.5 131.0 95.7 64.6 118.2 115.4 148.9 158.0 99.1 106.7 79.0 175.6 65.5 102.1 96.5 138.8 105.2 78.9 152.0 95.3 51.1 123.3 108.7 202.6 75.8 86.3 66.7 46.8 60.1 129.6 155.8 138.4 100.2 58.0 105.7 68.4 60.0 90.3 64.0 39.4 97.9 92.7 64.5 79.6 85.1 76.9 106.7 38.8 89.0 39.9 48.8 42.4 46.4 80.3 46.6 42.3 40.7 44.9 78.9 82.7 54.1 43.1 59.6 32.8 33.0 34.8 36.8 32.9 33.2 32.9 32.8 33.5 33.5 33.8 34.0 26.3 25.6 36.3 4.2 25.3 13.9 41.0 88.3 16.5 24.1 44.4 46.6 26.9 51.5 65.7 62.5 14.6 136.1 22.0 74.3 133.1 135.9 2.6 61.8 48.5 35.4 41.0 47.9 3.5 152.4 186.5 40.8 40.8 55.9 29.2 21.5 29.6 46.4 102.3 23.5 3.5 70.5 85.5 34.5 12.7 5.6 27.7 33.0 42.7 0.0 46.7 56.1 44.3 2.5 4.7 134.4 75.7 30.5 40.9 44.4 83.5 93.6 74.9 29.5 32.9 13.5 69.9 42.8 46.7 61.9 22.9 121.6 22.8 69.9 63.4 53.5 VPS36 "C13orf9, CGI-145, Eap45" ENSG00000136100 "Vacuolar protein sorting 36 homolog" Q86VN1 13 52412602-52450634 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 265.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039734, HPA043947" Approved Supported "Vesicles,Lysosomes,Plasma membrane,Cell Junctions" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 43: THP-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Vesicles, Lysosomes" "Plasma membrane, Cell Junctions" "HPA039734: AB_2676652, HPA043947: AB_2678744" "unprognostic (2.43e-1)" "unprognostic (1.44e-1)" "unprognostic (2.80e-1)" "unprognostic (2.94e-1)" "unprognostic (1.56e-1)" "unprognostic (2.32e-1)" "unprognostic (6.57e-2)" "unprognostic (7.84e-2)" "unprognostic (3.96e-3)" "unprognostic (1.19e-2)" "unprognostic (9.37e-2)" "unprognostic (5.57e-2)" "prognostic favorable (9.91e-6)" "unprognostic (6.47e-3)" "unprognostic (1.83e-1)" "unprognostic (1.94e-1)" "unprognostic (9.83e-2)" 17.1 15.1 10.1 16.8 11.5 8.6 26.1 14.0 16.3 20.0 9.6 24.5 27.6 18.7 12.2 23.7 16.8 16.6 24.0 11.8 10.1 25.4 23.6 19.9 19.5 12.4 11.0 17.9 17.9 23.3 11.0 25.0 12.8 21.8 27.5 43.1 25.2 18.3 23.4 51.1 27.7 20.7 9.9 24.1 18.1 4.0 12.1 22.3 22.5 26.2 20.7 18.9 21.3 12.1 7.3 11.8 20.4 13.5 21.1 29.3 17.8 16.7 12.5 16.1 9.6 14.3 22.9 25.5 8.6 23.8 10.6 20.1 16.6 19.7 18.0 19.3 16.0 30.2 18.7 12.8 25.3 40.2 31.4 20.5 37.9 11.2 18.0 18.0 16.6 33.6 22.7 21.8 31.8 9.6 30.4 40.6 19.5 29.0 6.3 31.0 11.9 15.9 28.7 18.9 10.4 22.0 11.9 27.3 25.9 24.0 15.9 67.1 26.3 10.3 12.6 10.3 19.1 16.3 22.0 26.8 10.6 28.4 24.7 15.6 14.6 12.3 12.3 16.3 19.8 15.3 13.5 15.4 15.6 13.0 12.2 13.1 3.6 21.6 22.7 16.3 16.0 13.7 10.1 11.5 14.0 16.3 11.8 10.1 12.4 11.0 12.8 9.9 12.1 12.1 54.2 83.3 51.5 41.1 49.9 42.8 48.9 57.6 62.0 132.2 51.6 72.8 80.8 38.6 47.7 33.1 120.9 60.2 83.4 62.6 68.4 35.4 1.2 28.0 45.9 55.7 49.8 31.1 57.0 29.3 43.0 46.6 36.7 37.0 44.3 44.9 38.2 54.0 43.8 52.2 54.6 64.1 40.7 44.0 29.1 3.7 49.7 47.1 28.4 36.5 60.8 39.8 59.8 44.7 40.7 29.8 63.0 52.3 55.0 65.4 77.4 78.5 33.2 265.8 46.0 52.7 76.1 15.3 25.9 83.5 58.2 38.2 48.2 40.6 58.6 45.4 VPS53 "FLJ10979, HCCS1" ENSG00000141252 "VPS53 subunit of GARP complex" Q5VIR6 17 508503-721717 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 270.0;Late spermatids: 203.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022988, HPA024446" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" Cytosol "HPA022988: AB_1848679, HPA024446: AB_1848680" "unprognostic (8.62e-3)" "unprognostic (7.98e-2)" "unprognostic (2.09e-1)" "prognostic favorable (1.08e-5)" "unprognostic (1.39e-2)" "unprognostic (9.08e-3)" "unprognostic (3.12e-1)" "unprognostic (9.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.53e-2)" "unprognostic (1.82e-2)" "unprognostic (1.89e-2)" "unprognostic (2.81e-1)" "unprognostic (4.82e-2)" "unprognostic (1.31e-1)" 4.3 4.7 7.0 3.0 5.9 20.5 4.6 21.4 10.3 5.2 2.8 4.5 3.7 4.4 3.4 9.0 4.0 3.6 4.3 8.2 3.3 4.0 4.5 5.1 4.9 3.0 3.9 5.3 4.5 6.4 6.0 4.6 4.2 4.6 5.9 8.1 4.7 5.0 7.0 7.1 4.0 6.1 0.9 4.5 5.0 14.6 4.0 4.9 7.6 5.1 5.2 4.1 4.8 9.4 12.9 26.5 7.6 8.3 12.4 9.5 5.5 6.4 9.4 15.8 15.4 12.6 5.8 7.8 5.9 19.9 10.0 10.9 16.5 13.9 23.1 6.7 11.4 5.0 17.2 8.1 6.1 6.6 9.2 11.1 7.8 14.7 9.8 6.4 11.7 9.7 9.1 9.1 14.9 8.9 4.3 5.1 6.2 5.6 6.9 10.5 3.9 5.2 8.0 10.4 7.6 6.1 12.4 4.3 5.4 7.5 6.5 3.5 7.9 6.8 5.4 12.5 7.0 4.3 3.3 4.8 11.5 5.2 8.6 8.1 1.9 4.4 2.4 2.3 1.8 2.1 2.2 1.7 1.1 3.0 2.3 1.9 6.1 1.9 5.6 3.0 1.9 0.9 7.0 5.9 21.4 10.3 8.2 3.3 3.0 3.9 4.2 0.9 4.0 9.4 16.0 12.8 25.9 54.5 19.3 25.5 16.5 11.6 19.9 53.3 19.6 9.3 17.4 14.3 21.5 40.5 70.9 10.5 19.9 24.9 1.9 16.7 270.0 23.9 22.2 18.7 24.6 5.0 109.3 18.3 7.9 18.5 26.5 28.1 24.1 18.2 15.7 17.7 21.4 63.9 103.6 27.4 4.1 20.6 19.4 203.9 18.6 21.0 10.6 39.4 27.5 18.3 37.0 48.2 62.5 25.3 15.5 23.0 20.6 18.7 21.0 10.6 24.3 52.2 6.6 31.1 20.7 46.0 35.3 24.6 38.8 8.9 26.8 17.2 22.0 19.6 VTA1 "C6orf55, HSPC228, My012" ENSG00000009844 "Vesicle trafficking 1" Q9NP79 6 142147162-142224685 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030968, HPA030969" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA 220000 "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Vesicles, Cytosol" "HPA030968: AB_10602585, HPA030969: AB_2673679" "prognostic unfavorable (7.02e-4)" "unprognostic (1.84e-2)" "unprognostic (2.12e-3)" "unprognostic (1.17e-2)" "unprognostic (1.08e-2)" "unprognostic (2.56e-2)" "prognostic unfavorable (6.58e-6)" "unprognostic (2.83e-2)" "unprognostic (3.61e-1)" "unprognostic (5.18e-2)" "unprognostic (2.84e-2)" "unprognostic (1.16e-1)" "unprognostic (3.85e-2)" "unprognostic (1.66e-1)" "unprognostic (1.64e-1)" "unprognostic (1.96e-1)" "unprognostic (3.24e-1)" 22.2 20.9 16.6 25.7 19.0 30.6 31.6 20.2 20.3 23.2 12.5 34.9 38.2 23.4 25.4 39.1 27.3 23.0 33.9 18.9 18.9 34.5 45.4 21.5 33.4 17.4 18.1 21.0 19.3 28.3 9.9 32.1 17.8 22.5 39.9 29.2 18.2 19.6 55.7 30.7 37.0 26.3 21.1 23.1 23.5 18.3 18.2 45.4 27.6 58.3 39.1 35.8 20.3 22.2 56.5 47.5 75.8 116.8 65.3 71.4 52.3 124.7 74.0 111.6 105.8 80.9 43.0 91.2 82.1 112.6 84.6 70.2 81.5 85.1 153.4 62.3 71.7 99.2 46.2 97.0 48.2 155.6 55.2 59.4 97.7 111.8 71.7 59.8 72.4 69.7 93.7 44.5 94.5 82.1 101.8 80.7 57.0 72.1 53.8 92.1 60.8 55.8 86.4 61.5 79.0 61.5 70.1 53.3 63.7 62.9 57.8 104.4 53.0 50.0 69.6 84.7 90.8 43.5 80.9 103.8 32.7 85.5 77.8 222.4 90.0 151.9 64.3 114.5 83.5 85.6 72.8 76.0 90.9 84.8 79.8 80.4 56.0 97.5 120.3 55.9 79.0 121.5 16.6 19.0 20.2 20.3 18.9 18.9 17.4 18.1 17.8 21.1 18.2 22.2 16.7 22.4 20.3 22.5 25.8 25.2 19.2 25.5 25.6 9.7 16.5 18.3 47.8 12.8 24.5 16.5 0.0 32.7 23.9 40.2 17.6 31.5 4.5 30.7 30.4 17.5 21.6 23.1 40.1 28.0 36.4 25.4 16.8 28.0 12.6 18.1 11.4 24.7 27.9 11.8 38.7 24.7 14.2 20.9 14.3 2.2 11.8 20.0 8.8 40.3 28.0 23.9 35.0 25.6 48.7 30.1 18.3 12.4 16.4 17.2 30.0 31.6 36.6 12.6 6.6 16.8 18.4 23.6 24.9 28.8 31.0 31.7 23.8 25.3 25.9 18.8 VTI1A "MVti1, Vti1-rp2" ENSG00000151532 "Vesicle transport through interaction with t-SNAREs 1A" Q96AJ9 10 112446998-112818744 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 135.2;Excitatory neurons: 244.7;Inhibitory neurons: 199.5;Late spermatids: 102.8;Microglial cells: 195.8;Oligodendrocyte precursor cells: 172.4;Oligodendrocytes: 218.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054108 Supported Supported "Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Vesicles" "HPA054108: AB_2682382" "unprognostic (9.81e-2)" "unprognostic (6.42e-2)" "unprognostic (4.49e-2)" "unprognostic (1.50e-1)" "unprognostic (1.66e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.50e-5)" "unprognostic (1.71e-1)" "unprognostic (1.59e-1)" "unprognostic (2.00e-1)" "unprognostic (1.22e-1)" "unprognostic (8.05e-2)" "prognostic favorable (7.27e-5)" "unprognostic (3.74e-2)" "unprognostic (1.98e-1)" "unprognostic (1.67e-3)" "unprognostic (2.61e-1)" 6.6 4.7 3.7 7.0 3.7 13.8 4.7 2.3 4.7 3.5 1.1 6.4 7.2 3.8 4.9 7.3 3.2 4.6 5.8 4.8 2.6 6.8 4.7 5.1 7.7 2.8 3.7 3.1 3.9 7.5 2.6 4.0 3.5 4.7 7.5 4.2 5.2 4.8 7.4 5.9 7.2 5.7 1.8 5.6 5.5 4.5 4.3 8.6 6.3 6.1 9.4 5.2 4.4 4.6 13.5 11.2 10.1 14.1 15.5 13.4 6.1 14.1 17.4 11.0 12.2 12.7 13.6 14.0 5.3 16.0 9.3 15.6 8.8 11.2 14.9 18.0 8.1 11.9 8.1 13.3 11.0 16.8 16.8 10.4 13.9 12.6 25.9 12.4 11.9 14.1 11.3 16.9 14.8 9.5 13.3 12.8 4.4 10.5 6.5 13.9 14.6 6.2 11.5 11.9 4.6 9.0 10.0 8.6 9.5 8.4 7.8 9.3 17.0 8.7 7.4 10.8 15.8 7.4 11.0 15.9 14.2 15.3 8.6 9.2 7.0 9.6 5.4 9.3 5.1 5.5 4.5 4.4 5.2 4.6 4.3 4.4 11.4 5.7 8.7 4.9 7.2 4.6 3.7 3.7 2.3 4.7 4.8 2.6 2.8 3.7 3.5 1.8 4.3 4.6 13.5 12.8 10.3 135.2 33.1 11.2 14.5 8.8 13.6 16.5 7.8 4.6 14.0 7.2 11.6 5.5 43.8 7.6 31.5 17.0 7.9 15.4 42.9 11.4 15.5 13.6 18.5 18.1 244.7 25.0 12.3 12.9 21.9 17.0 19.6 10.2 8.9 8.1 18.8 21.9 199.5 10.7 14.2 17.0 27.0 102.8 6.8 20.9 12.4 195.8 19.0 6.0 25.7 172.4 218.6 29.7 12.2 5.7 23.9 12.6 17.2 9.4 11.7 20.7 0.0 13.5 14.1 11.1 9.2 17.0 16.3 14.4 25.4 9.7 12.1 19.7 VTN VN ENSG00000109072 Vitronectin P04004 17 28367284-28373091 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "liver: 6039.5" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 5507.4" "Cancer enriched" "Detected in many" 85 "liver cancer: 2216.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "CACO-2: 1748.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016695, CAB016765, HPA060933, HPA068011" Supported Supported "Endoplasmic reticulum,Vesicles" "Secreted to blood" NA NA 606000000000 33000000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Vesicles" "CAB016695: AB_1624536, CAB016765: , HPA060933: AB_2684389, HPA068011: " "unprognostic (1.19e-1)" "unprognostic (2.12e-1)" "unprognostic (2.29e-2)" "unprognostic (6.13e-2)" "unprognostic (9.74e-2)" "unprognostic (8.42e-2)" "prognostic favorable (3.74e-4)" "unprognostic (6.20e-2)" "unprognostic (3.97e-1)" "unprognostic (8.95e-2)" "unprognostic (3.24e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.10e-11)" "unprognostic (8.82e-3)" "unprognostic (2.27e-1)" "unprognostic (4.86e-3)" "unprognostic (7.09e-2)" 6.2 98.9 2.4 2.5 2.7 0.3 0.9 5.4 3.7 1.0 0.4 0.9 4.6 1.4 0.9 0.5 2.2 61.2 53.1 2.5 2.8 3.6 6039.5 1.8 4.3 2.1 5.3 1.9 17.7 0.1 3.0 40.6 2.3 1.2 0.3 47.4 0.6 4.3 0.4 0.8 1.3 2.7 1.5 2.9 5.1 10.0 2.2 0.1 0.8 0.5 0.4 4.2 0.7 2.4 0.0 28.4 0.7 0.4 0.2 0.3 7.3 1.8 0.8 0.9 0.9 1748.9 0.1 1.2 0.2 0.2 0.2 0.7 0.0 0.0 0.1 0.2 0.2 1.2 1.1 86.7 2.5 6.1 0.5 0.4 0.0 0.6 0.0 3.9 0.1 0.0 1.6 0.3 0.2 0.7 0.2 0.0 0.8 0.4 0.1 0.4 3.5 0.1 0.3 0.0 1.0 1.4 115.6 8.0 0.2 4.3 0.3 0.0 1.0 0.4 0.3 0.1 0.2 1.0 0.5 1.4 0.5 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 2.4 2.7 5.4 3.7 2.5 2.8 2.1 5.3 2.3 1.5 2.2 2.4 0.1 0.0 1.1 2.0 21.5 0.0 0.0 0.0 0.0 13.0 0.1 0.1 18.1 1162.4 0.0 0.0 77.2 3.7 0.0 0.0 3.9 16.8 0.0 0.0 1.2 7.3 0.0 131.0 0.9 19.7 2.8 48.1 0.0 0.0 0.0 1.8 120.3 5507.4 4.7 38.7 1.0 0.1 0.0 160.3 0.3 0.2 0.0 0.3 0.0 0.0 20.1 6.9 0.0 1.0 0.5 23.5 1.2 1.5 0.0 0.0 0.1 9.5 0.0 38.3 0.0 0.4 1.5 4.2 0.6 0.0 0.0 9.6 9.0 0.7 0.0 0.0 VWCE "FLJ32009, URG11, VWC1" ENSG00000167992 "Von Willebrand factor C and EGF domains" Q96DN2 11 61258286-61295316 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 14.3;ovary: 7.9" "Cell type enhanced" "Detected in many" "Astrocytes: 19.2;Cone photoreceptor cells: 29.2;Hepatocytes: 16.4;Rod photoreceptor cells: 21.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 7.2;Hep G2: 26.3;HSkMC: 13.4;REH: 14.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA040401, HPA043921" Uncertain Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2200000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Vesicles, Cytosol" "HPA040401: AB_2676963, HPA043921: AB_2678731" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (3.58e-2)" "unprognostic (1.15e-1)" "unprognostic (3.96e-3)" "unprognostic (9.27e-4)" "unprognostic (1.21e-2)" "unprognostic (4.01e-4)" "unprognostic (3.04e-2)" "unprognostic (3.42e-2)" "unprognostic (6.58e-4)" "unprognostic (7.20e-2)" "unprognostic (3.01e-1)" "unprognostic (1.25e-2)" "unprognostic (1.92e-1)" "unprognostic (2.34e-1)" "unprognostic (2.30e-1)" 2.8 1.1 0.6 0.1 0.9 1.6 1.5 0.3 1.6 2.9 0.0 0.6 0.3 1.3 0.6 0.9 3.5 0.6 0.8 0.7 0.7 0.5 14.3 0.3 0.2 0.5 1.2 7.9 0.3 0.1 0.6 2.4 0.4 1.0 0.4 0.8 0.9 0.5 0.7 0.7 0.4 0.4 0.0 0.4 0.4 1.8 0.5 2.5 0.8 0.4 0.1 0.6 1.2 0.2 0.0 0.1 1.5 0.2 0.2 1.8 0.6 0.2 2.0 0.0 0.3 7.2 0.0 0.5 0.0 0.4 0.1 0.0 2.3 0.0 0.1 0.4 0.0 0.8 0.0 26.3 1.2 0.0 0.3 13.4 0.6 0.7 0.0 0.1 2.3 3.3 0.2 0.3 0.3 0.1 5.5 0.0 2.2 0.0 0.0 14.0 0.2 0.0 0.1 0.1 0.6 1.0 0.0 0.1 0.7 2.4 0.9 0.0 0.8 0.3 0.3 0.5 0.2 0.2 0.6 1.2 0.9 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.3 1.6 0.7 0.7 0.5 1.2 0.4 0.0 0.5 0.2 2.1 3.2 1.7 19.2 0.3 1.8 1.8 3.8 3.4 3.6 1.7 0.5 1.0 1.5 2.3 0.0 29.2 1.0 0.5 0.2 0.0 0.1 0.5 2.9 1.0 5.5 1.8 6.1 7.5 0.5 5.0 2.6 0.0 1.8 3.8 6.5 2.5 16.4 1.2 0.0 5.8 0.1 2.0 3.5 2.4 0.8 6.8 2.6 1.8 2.8 2.3 2.3 1.0 2.5 1.4 0.0 0.0 1.9 0.4 1.1 0.1 0.3 5.4 21.1 0.0 0.9 1.1 1.1 3.4 1.3 2.3 4.4 0.9 7.7 0.3 0.7 WASHC1 "FAM39E, FLJ00038, WASH1" ENSG00000181404 "WASH complex subunit 1" A8K0Z3 9 14475-73865 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 60.7;Distal tubular cells: 50.9;Proximal tubular cells: 47.5;Syncytiotrophoblasts: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA002689 Uncertain Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA002689: AB_1078803" "unprognostic (9.43e-2)" "unprognostic (1.62e-2)" "unprognostic (3.16e-2)" "unprognostic (1.30e-1)" "unprognostic (1.43e-1)" "unprognostic (2.33e-2)" "unprognostic (3.22e-3)" "unprognostic (2.06e-2)" "unprognostic (5.00e-1)" "unprognostic (5.40e-3)" "unprognostic (3.37e-3)" "unprognostic (6.95e-2)" "unprognostic (3.90e-2)" "unprognostic (1.88e-1)" "unprognostic (3.38e-1)" "unprognostic (2.31e-2)" "unprognostic (1.02e-1)" 15.7 18.1 13.2 7.1 14.2 16.3 17.6 13.2 15.1 24.5 16.5 19.6 10.2 20.3 21.9 19.2 24.1 9.0 17.9 13.3 13.5 25.9 20.9 17.1 13.4 14.4 13.8 23.0 21.9 5.2 21.2 6.6 14.3 27.0 4.7 15.9 17.6 13.5 22.8 26.1 21.9 15.3 13.4 29.0 18.3 24.1 14.5 8.6 22.1 6.8 6.0 19.7 20.5 14.9 13.5 8.5 5.0 10.3 8.5 5.7 12.4 11.7 11.4 6.9 5.5 8.4 8.3 5.7 6.6 4.8 6.2 16.7 7.4 5.7 2.5 5.9 14.4 5.5 7.0 8.6 4.7 11.3 10.0 4.3 4.2 3.5 4.7 17.3 2.1 5.0 12.6 21.0 2.2 4.0 11.6 9.4 9.2 9.1 10.5 7.9 4.3 7.2 5.1 9.8 5.6 14.9 6.8 14.3 8.6 6.2 8.6 10.5 8.0 9.2 6.7 4.0 10.3 9.4 7.9 4.5 8.6 12.0 8.6 1.2 2.5 2.2 1.9 2.7 1.5 1.3 1.5 1.6 2.3 1.2 1.6 1.3 1.4 2.1 4.0 2.1 1.8 1.5 13.2 14.2 13.2 15.1 13.3 13.5 14.4 13.8 14.3 13.4 14.5 14.9 34.5 22.4 22.5 0.0 10.5 0.0 0.0 0.0 0.0 0.0 29.0 28.3 0.0 0.0 7.4 60.7 0.0 37.4 21.5 0.0 50.9 13.7 0.0 24.7 28.6 7.5 0.0 0.0 0.0 15.8 26.1 10.8 0.0 22.9 16.4 27.3 0.0 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 4.6 0.0 0.0 0.0 0.0 13.1 0.0 0.0 6.7 0.0 0.0 47.5 8.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 42.8 11.4 14.3 0.0 0.0 WASHC2A "bA56A21.1, bA98I6.1, FAM21A, FAM21B, FLJ10824" ENSG00000099290 "WASH complex subunit 2A" Q641Q2 10 50067888-50133509 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Alveolar cells type 2: 28.5;Endometrial ciliated cells: 45.7;Respiratory ciliated cells: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA047844, HPA060975, HPA061022" Supported Supported Nucleoli,Vesicles,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli, Cytosol" "HPA047844: AB_2680177, HPA060975: AB_2684401, HPA061022: AB_2732656" "unprognostic (2.46e-1)" "unprognostic (1.11e-3)" "unprognostic (8.82e-2)" "unprognostic (3.28e-1)" "unprognostic (2.75e-1)" "unprognostic (6.51e-3)" "prognostic unfavorable (6.75e-5)" "unprognostic (4.60e-2)" "unprognostic (2.85e-2)" "unprognostic (2.37e-2)" "unprognostic (9.04e-2)" "unprognostic (2.73e-2)" "unprognostic (1.18e-1)" "unprognostic (2.57e-1)" "unprognostic (2.95e-1)" "unprognostic (1.85e-2)" "unprognostic (4.40e-2)" 25.3 25.9 19.9 22.1 20.7 37.5 24.0 23.4 24.8 24.7 18.3 28.9 25.2 22.5 19.2 20.2 19.7 18.0 58.6 19.9 19.9 22.9 15.5 26.0 28.8 21.1 21.2 26.7 17.7 23.3 21.5 22.9 21.1 20.6 28.9 19.9 21.9 20.0 22.3 25.7 28.9 21.2 18.6 26.6 21.5 12.5 22.6 24.2 23.3 15.6 26.9 23.8 22.1 23.9 26.1 12.5 21.1 24.3 83.2 46.0 16.9 29.8 64.0 43.7 46.6 28.8 37.8 22.5 18.1 44.8 41.3 28.0 31.2 25.3 43.2 22.2 22.0 15.9 25.6 29.7 58.6 28.0 27.2 47.8 31.2 47.6 30.5 46.2 33.1 19.2 26.6 22.2 53.9 19.1 15.5 48.0 17.1 16.7 58.4 23.1 30.1 13.7 30.5 29.3 7.3 22.4 27.8 25.9 40.9 30.9 31.6 19.2 49.4 22.0 18.5 62.7 25.0 23.4 48.3 19.1 48.9 51.4 9.0 1.0 9.1 9.9 9.1 11.6 10.1 5.1 8.0 8.8 7.3 4.9 7.7 6.0 4.1 8.2 6.9 4.6 9.2 7.9 19.9 20.7 23.4 24.8 19.9 19.9 21.1 21.2 21.1 18.6 22.6 23.9 16.2 38.5 28.5 0.0 3.3 0.0 0.0 0.0 0.0 0.0 10.6 11.0 0.0 0.0 22.9 14.7 0.0 7.4 10.0 0.0 0.0 16.7 0.0 45.7 19.9 7.9 0.0 0.0 0.0 15.6 6.9 8.9 0.0 20.3 15.2 13.5 0.0 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 5.7 0.0 0.0 0.0 0.0 15.1 0.0 0.0 2.6 0.0 0.0 11.7 41.5 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 7.7 7.8 9.4 0.0 0.0 WASHC2C "Em:AC012044.3, FAM21C, KIAA0592" ENSG00000172661 "WASH complex subunit 2C" Q9Y4E1 10 45727200-45792964 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 35.3;Alveolar cells type 2: 35.2;Collecting duct cells: 23.9;granulocytes: 30.3;Respiratory ciliated cells: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA047844, HPA060975, HPA061022" Supported Supported Nucleoli,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli, Cytosol" "HPA047844: AB_2680177, HPA060975: AB_2684401, HPA061022: AB_2732656" "unprognostic (7.50e-2)" "unprognostic (2.32e-2)" "unprognostic (1.13e-1)" "unprognostic (1.06e-1)" "unprognostic (4.51e-2)" "unprognostic (5.98e-3)" "prognostic unfavorable (1.35e-5)" "prognostic favorable (4.69e-4)" "unprognostic (1.26e-1)" "unprognostic (5.02e-2)" "unprognostic (1.00e-3)" "unprognostic (1.51e-1)" "unprognostic (2.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (2.00e-2)" 19.4 15.7 10.9 17.3 11.8 42.5 17.5 14.8 14.9 19.1 13.5 20.3 15.2 16.8 12.4 13.5 14.9 16.5 22.0 11.3 11.4 18.0 15.9 17.7 20.2 12.5 12.2 21.6 11.6 21.4 13.9 13.7 12.7 15.6 22.0 14.2 15.3 14.6 17.1 17.6 19.7 19.0 9.6 19.3 15.0 12.9 14.1 21.2 17.1 9.8 18.7 17.7 14.6 14.0 24.5 25.9 20.7 23.5 52.1 45.8 12.4 28.4 45.8 32.4 30.8 16.0 23.3 20.1 18.8 41.7 30.8 21.6 23.2 13.0 32.6 18.9 19.2 20.9 32.3 12.3 55.0 21.4 24.6 43.4 30.4 35.4 26.1 31.6 33.7 16.5 33.9 15.7 40.1 12.8 14.0 35.9 14.8 14.7 3.9 17.4 30.5 10.5 23.8 38.2 10.0 22.3 32.8 16.1 39.4 21.0 22.1 20.6 58.1 16.8 18.0 44.7 19.1 21.5 36.3 19.6 23.5 49.4 9.2 14.1 17.1 11.7 12.2 17.9 11.8 9.9 10.1 12.7 11.7 9.2 10.0 8.9 16.8 12.5 22.8 8.1 10.4 13.3 10.9 11.8 14.8 14.9 11.3 11.4 12.5 12.2 12.7 9.6 14.1 14.0 16.2 35.3 35.2 0.0 3.0 0.0 0.0 0.0 0.0 0.0 11.3 8.8 0.0 0.0 11.8 23.9 0.0 6.8 11.8 0.0 3.9 13.5 0.0 11.3 17.9 6.1 0.0 0.0 0.0 14.0 6.4 7.9 0.0 13.9 30.3 13.7 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 10.3 0.0 0.0 0.0 0.0 11.9 0.0 0.0 3.8 0.0 0.0 12.8 24.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 7.8 7.0 12.1 0.0 0.0 WDFY1 "FENS-1, KIAA1435, WDF1, ZFYVE17" ENSG00000085449 "WD repeat and FYVE domain containing 1" Q8IWB7 2 223855716-223945357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050603, HPA079597" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Vesicles" "HPA050603: AB_2681188, HPA079597: " "unprognostic (2.49e-1)" "unprognostic (1.24e-1)" "unprognostic (2.94e-1)" "unprognostic (7.62e-2)" "unprognostic (8.24e-2)" "unprognostic (5.31e-2)" "unprognostic (2.63e-2)" "unprognostic (7.10e-2)" "unprognostic (1.26e-1)" "unprognostic (2.29e-2)" "unprognostic (1.23e-3)" "unprognostic (1.36e-1)" "unprognostic (3.81e-3)" "unprognostic (3.94e-1)" "unprognostic (2.98e-1)" "unprognostic (3.04e-1)" "unprognostic (7.55e-2)" 18.6 13.2 9.3 18.0 9.5 48.5 14.4 9.3 12.0 20.5 11.2 20.4 15.6 22.6 19.8 14.4 20.5 17.5 11.7 9.2 10.7 14.8 18.0 18.4 23.3 11.0 10.2 20.2 14.1 19.8 8.7 27.4 11.4 16.2 20.1 15.9 13.5 12.8 11.4 13.5 15.9 19.6 9.7 21.2 19.8 10.9 10.5 15.9 22.1 12.6 18.9 17.9 13.7 11.1 27.9 19.3 34.9 27.2 46.4 44.0 43.7 34.7 48.3 37.5 30.4 81.4 25.0 7.7 30.8 60.6 47.3 19.2 18.7 52.3 40.4 15.6 15.8 19.2 31.9 59.2 36.4 15.2 15.8 39.0 37.9 46.3 71.0 62.4 63.9 16.2 34.3 23.4 44.4 26.8 6.5 11.1 34.5 20.7 16.6 25.3 44.8 8.6 28.4 47.7 29.6 15.7 20.7 19.2 90.9 41.6 12.5 38.1 70.9 74.9 25.7 13.5 18.0 28.8 4.6 21.4 36.3 32.9 26.2 4.4 21.5 8.1 13.7 29.0 16.6 14.1 9.7 13.5 14.8 11.7 10.0 9.5 10.3 24.0 25.7 3.0 9.7 17.6 9.3 9.5 9.3 12.0 9.2 10.7 11.0 10.2 11.4 9.7 10.5 11.1 40.0 16.0 9.3 22.5 22.0 12.5 14.5 19.9 17.1 14.0 11.8 7.6 7.7 12.8 24.4 16.5 8.4 22.6 25.5 36.4 9.8 12.9 0.8 23.2 30.7 34.1 10.3 11.2 28.7 17.2 11.2 21.4 29.6 36.5 17.7 12.5 16.8 25.7 17.9 28.6 28.1 15.2 8.2 26.3 17.2 2.4 14.6 24.4 35.6 27.2 25.6 13.9 24.7 33.7 39.8 18.0 24.4 23.7 21.8 16.6 16.0 14.4 29.9 10.9 6.6 13.1 26.7 3.8 8.8 24.4 15.5 19.0 21.1 15.0 21.8 28.7 WDFY2 ZFYVE22 ENSG00000139668 "WD repeat and FYVE domain containing 2" Q96P53 13 51584455-51767709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 301.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050094 Supported Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA050094: " "unprognostic (2.95e-1)" "unprognostic (1.78e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-3)" "unprognostic (1.59e-1)" "unprognostic (2.41e-1)" "unprognostic (1.39e-2)" "unprognostic (9.58e-2)" "unprognostic (2.28e-1)" "unprognostic (2.59e-2)" "unprognostic (3.87e-2)" "unprognostic (1.14e-1)" "unprognostic (7.49e-4)" "unprognostic (1.47e-1)" "unprognostic (7.04e-2)" "unprognostic (6.36e-2)" "unprognostic (2.48e-1)" 6.7 11.2 8.9 4.5 12.1 15.0 7.6 9.0 8.8 8.4 4.8 3.9 1.9 5.1 5.5 9.5 6.5 2.9 3.8 8.9 10.4 4.5 6.4 5.4 4.7 11.5 9.9 8.1 17.5 15.0 5.2 5.4 12.4 5.1 2.3 6.0 5.6 4.9 1.6 17.7 4.3 3.6 10.0 7.5 6.5 6.5 10.2 4.4 5.9 3.0 5.1 4.3 8.6 15.4 1.4 2.6 11.3 4.6 5.4 11.2 3.6 11.0 7.0 5.6 4.4 1.7 1.5 4.5 1.0 7.6 3.6 5.0 6.3 19.7 10.6 3.7 3.5 9.6 3.8 13.6 4.3 6.5 4.4 9.1 9.3 12.5 14.2 9.1 2.5 4.8 2.7 2.3 9.3 3.1 4.5 14.8 13.4 3.2 3.7 5.9 4.5 3.0 7.2 3.8 3.1 7.5 3.3 4.9 5.0 9.3 2.3 15.5 9.4 10.6 2.0 5.2 7.8 1.5 2.6 3.2 12.1 6.6 13.3 6.1 7.8 4.0 2.2 8.6 3.1 3.8 2.4 1.9 13.0 4.2 2.1 2.7 5.2 4.0 9.5 11.9 3.5 3.5 8.9 12.1 9.0 8.8 8.9 10.4 11.5 9.9 12.4 10.0 10.2 15.4 16.3 16.0 21.9 118.2 36.9 23.3 20.0 10.2 45.5 35.2 25.7 24.0 7.1 8.6 17.5 29.5 127.2 28.5 41.2 7.0 27.4 19.8 46.3 19.3 23.6 13.0 13.8 17.1 47.1 23.5 33.7 20.7 14.8 20.2 29.7 35.3 27.1 18.1 28.1 37.0 47.1 9.2 8.2 63.8 30.8 19.9 39.4 41.3 12.4 96.5 45.9 26.4 16.5 106.6 301.8 15.0 4.5 21.8 17.1 12.2 9.2 6.4 14.9 52.5 26.3 45.1 27.1 32.3 16.5 46.4 27.1 14.0 27.3 41.7 10.0 16.2 WDR24 "C16orf21, DKFZp434F054, JFP7" ENSG00000127580 "WD repeat domain 24" Q96S15 16 684622-690444 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 48.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039506 Approved Supported Vesicles,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Vesicles Cytosol "HPA039506: AB_10795148" "unprognostic (9.07e-2)" "unprognostic (2.67e-3)" "unprognostic (6.67e-2)" "unprognostic (1.48e-1)" "unprognostic (1.67e-1)" "unprognostic (8.15e-2)" "unprognostic (7.05e-2)" "unprognostic (4.35e-2)" "unprognostic (1.75e-1)" "unprognostic (5.09e-3)" "unprognostic (2.29e-3)" "unprognostic (2.05e-1)" "prognostic favorable (3.75e-6)" "unprognostic (5.38e-2)" "unprognostic (3.16e-1)" "unprognostic (1.52e-1)" "unprognostic (2.82e-2)" 6.1 9.1 3.9 4.0 3.6 3.9 6.2 5.0 6.9 7.5 4.1 7.1 4.8 7.9 1.0 7.1 7.5 2.8 7.9 3.8 3.0 7.5 11.2 6.0 4.8 4.2 4.0 9.2 7.2 5.8 9.4 3.2 3.5 8.5 1.1 1.8 6.9 3.0 11.7 8.5 7.1 2.0 3.2 9.2 7.8 14.2 3.9 4.3 8.7 4.1 2.4 7.5 6.6 3.7 6.1 14.0 6.2 8.6 5.9 4.2 10.9 7.5 6.7 9.2 8.0 15.3 8.8 9.4 12.8 3.4 2.3 9.4 6.1 7.4 2.0 15.9 19.0 6.4 19.8 5.8 9.4 7.9 9.6 7.4 4.9 6.6 5.5 4.8 5.0 9.0 12.7 10.3 3.4 22.2 14.0 5.8 9.7 3.1 10.6 20.4 5.1 17.6 3.0 4.2 15.1 6.9 8.5 14.3 8.7 2.8 13.2 7.8 7.3 6.6 6.8 7.4 7.3 21.9 21.5 15.3 4.3 7.8 9.4 4.3 5.1 2.8 6.6 3.0 5.4 4.3 4.2 4.9 5.1 3.7 4.9 4.8 1.2 3.0 7.8 4.1 6.1 5.0 3.9 3.6 5.0 6.9 3.8 3.0 4.2 4.0 3.5 3.2 3.9 3.7 2.9 6.4 6.2 2.3 4.2 1.1 2.6 4.7 4.0 5.1 5.2 4.4 5.0 1.5 5.0 7.3 2.1 7.4 2.9 6.0 7.9 4.9 17.1 12.2 2.9 3.1 10.1 5.2 2.0 5.6 4.4 3.1 6.6 2.9 4.5 6.9 2.5 9.6 5.1 21.9 2.0 7.3 4.1 6.3 1.6 48.0 5.6 3.9 0.0 1.9 4.4 7.3 1.0 2.0 2.4 4.5 2.1 3.0 6.8 3.8 8.0 6.4 19.4 2.6 19.7 2.6 4.2 18.8 8.7 2.1 1.6 7.4 3.4 7.6 5.5 2.0 WDR48 "KIAA1449, P80, SPG60" ENSG00000114742 "WD repeat domain 48" Q8TAF3 3 39052013-39096671 "Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 104.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038421, HPA058015" Approved Supported Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA038421: AB_10670780, HPA058015: AB_2683580" "unprognostic (1.95e-1)" "unprognostic (2.14e-1)" "unprognostic (2.99e-2)" "unprognostic (3.78e-1)" "unprognostic (7.68e-2)" "unprognostic (2.34e-3)" "unprognostic (6.14e-3)" "unprognostic (9.87e-3)" "unprognostic (8.02e-2)" "unprognostic (2.22e-2)" "unprognostic (2.28e-1)" "unprognostic (2.14e-2)" "prognostic favorable (1.63e-7)" "unprognostic (2.41e-1)" "unprognostic (2.94e-2)" "unprognostic (1.43e-1)" "unprognostic (1.69e-2)" 14.1 15.5 20.7 13.3 22.2 35.1 17.7 20.3 25.7 17.7 17.1 14.3 15.1 20.0 14.1 14.0 15.7 13.2 16.2 21.9 22.9 21.4 16.1 13.9 17.6 21.2 21.8 21.1 16.1 22.0 4.4 20.8 21.3 16.0 15.1 17.9 15.4 20.9 11.5 14.1 15.1 16.9 21.6 16.1 14.2 47.9 22.8 26.8 24.8 17.1 19.4 16.8 6.3 24.2 11.6 16.4 32.9 23.6 23.8 27.2 14.4 14.4 20.6 17.6 22.5 11.5 12.7 27.8 10.0 20.2 15.7 13.8 30.3 18.7 20.5 70.3 38.8 26.1 22.8 19.0 10.8 18.8 13.7 18.1 21.2 19.0 21.9 31.9 21.8 20.1 30.7 27.8 16.3 9.9 24.6 20.1 36.3 16.8 19.8 9.6 17.3 24.1 21.9 24.2 24.1 29.0 14.7 29.8 25.4 29.0 15.6 26.7 18.8 15.9 12.0 14.7 16.2 30.2 48.6 22.7 18.5 16.9 15.5 13.3 6.0 7.5 9.2 7.9 9.1 9.4 10.6 10.7 8.7 10.9 10.7 9.3 8.0 15.1 13.0 7.2 12.6 8.9 20.7 22.2 20.3 25.7 21.9 22.9 21.2 21.8 21.3 21.6 22.8 24.2 27.0 16.0 22.0 45.4 26.6 17.6 13.3 9.2 20.5 21.6 18.1 16.6 23.2 7.2 15.5 11.0 16.7 15.9 26.0 14.4 17.6 13.9 77.2 20.2 28.5 20.6 22.1 17.9 35.3 12.4 12.2 18.0 9.7 29.7 24.1 25.5 16.1 13.0 8.6 21.9 37.0 13.7 4.1 11.4 15.9 71.9 18.6 16.2 14.2 26.2 19.8 23.6 13.4 38.7 41.1 12.0 12.9 16.6 20.9 21.9 17.3 13.4 17.8 17.9 26.3 21.9 19.2 104.5 59.9 16.7 21.2 21.5 25.7 23.0 12.3 19.5 WDR81 "CAMRQ2, FLJ33817, PPP1R166, SORF-2" ENSG00000167716 "WD repeat domain 81" Q562E7 17 1716523-1738599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 27.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023044, HPA063703" Uncertain Approved Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Vesicles, Cytosol" "HPA023044: AB_1858822, HPA063703: " "unprognostic (1.00e-1)" "unprognostic (4.67e-2)" "unprognostic (6.63e-2)" "unprognostic (4.90e-3)" "unprognostic (6.10e-2)" "unprognostic (7.75e-3)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (3.06e-2)" "unprognostic (1.60e-2)" "prognostic favorable (3.30e-4)" "unprognostic (3.26e-1)" "unprognostic (8.72e-2)" "unprognostic (2.25e-1)" "unprognostic (8.43e-2)" "unprognostic (7.99e-2)" "unprognostic (3.90e-2)" 17.7 16.2 4.5 4.6 5.4 4.9 16.9 4.6 6.3 18.2 6.6 11.5 4.8 18.9 2.4 9.9 17.4 1.6 10.9 4.3 4.4 11.9 32.8 13.7 5.6 5.9 5.1 21.4 11.0 2.4 13.1 3.9 5.3 16.0 1.7 0.8 11.0 5.9 18.2 18.4 17.8 5.1 4.7 24.3 11.0 7.5 6.1 6.6 10.5 2.1 4.2 15.4 13.7 6.4 0.7 12.3 1.7 9.1 12.4 7.0 9.2 0.9 0.2 0.6 0.0 1.8 4.4 4.9 6.5 5.4 6.2 12.2 6.3 8.4 0.4 9.5 12.8 0.3 8.8 5.9 22.1 4.1 7.6 17.8 8.8 5.9 4.1 1.9 5.0 3.7 1.0 6.3 7.6 6.8 1.3 7.6 3.9 4.2 9.4 6.4 2.9 6.8 3.7 2.0 2.2 5.0 4.3 3.4 15.4 0.1 6.0 6.1 6.8 4.8 5.4 7.9 6.7 0.5 1.3 3.1 7.7 5.9 2.4 0.0 1.4 2.8 1.1 2.3 1.3 1.3 1.2 1.2 1.8 1.0 0.8 1.1 0.3 2.1 2.3 3.3 1.2 1.1 4.5 5.4 4.6 6.3 4.3 4.4 5.9 5.1 5.3 4.7 6.1 6.4 6.3 12.8 10.3 6.5 4.2 2.5 2.9 4.4 8.6 4.5 4.8 5.3 3.6 4.3 3.8 0.0 4.2 2.5 9.9 6.8 1.9 3.1 0.7 2.1 6.2 5.4 1.2 14.3 5.3 4.5 1.9 8.2 6.6 2.9 4.5 6.2 4.6 27.7 23.8 5.0 5.3 4.6 10.2 22.3 4.5 1.2 16.4 15.3 0.0 9.4 7.5 2.5 9.2 5.0 7.6 4.8 4.8 15.1 5.3 2.9 8.7 20.1 6.4 1.8 19.7 5.9 4.5 0.7 2.0 3.4 1.7 2.3 4.7 5.8 4.4 1.7 WDTC1 "ADP, DCAF9, KIAA1037" ENSG00000142784 "WD and tetratricopeptide repeats 1" Q8N5D0 1 27234632-27308636 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028177, HPA028180, HPA028182" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles "Golgi apparatus" "HPA028177: AB_10600419, HPA028180: AB_10601676, HPA028182: AB_10602204" "unprognostic (3.18e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.69e-2)" "unprognostic (8.28e-2)" "unprognostic (3.31e-2)" "unprognostic (2.00e-3)" "unprognostic (1.25e-2)" "unprognostic (9.44e-2)" "unprognostic (2.44e-1)" "unprognostic (5.45e-3)" "unprognostic (1.41e-3)" "unprognostic (1.73e-1)" "prognostic favorable (8.84e-8)" "unprognostic (1.28e-1)" "unprognostic (9.33e-2)" "unprognostic (3.01e-2)" "unprognostic (2.51e-2)" 16.5 24.4 25.4 10.5 22.3 14.7 17.5 20.2 25.4 18.9 12.7 24.7 12.9 19.7 7.0 18.0 19.9 10.5 35.9 21.8 20.0 19.9 18.7 16.9 14.4 25.3 21.0 19.0 22.1 47.7 16.9 10.6 24.4 19.3 9.5 33.5 20.1 15.1 63.0 24.8 18.0 12.0 19.4 17.7 23.2 37.6 23.5 19.8 18.4 54.4 12.7 19.8 18.5 21.1 19.8 8.6 13.5 1.3 18.9 15.8 5.6 12.0 20.1 12.7 15.5 2.9 19.3 17.0 14.0 24.0 9.3 10.1 13.0 18.4 11.0 23.2 22.0 17.7 8.9 7.9 17.0 9.0 22.4 15.1 29.6 15.8 14.4 22.9 17.4 5.4 18.2 17.2 13.6 11.1 14.6 21.6 6.3 13.0 18.1 7.3 10.1 18.7 15.2 4.2 19.7 16.9 15.7 6.6 14.4 10.1 9.8 15.5 15.2 10.3 6.2 14.5 5.9 24.7 14.2 8.1 20.8 17.3 12.5 0.1 0.2 2.7 1.4 0.3 0.5 0.6 0.3 0.6 0.7 0.4 0.2 0.6 2.1 0.4 0.2 0.5 0.4 0.5 25.4 22.3 20.2 25.4 21.8 20.0 25.3 21.0 24.4 19.4 23.5 21.1 10.8 9.6 10.7 19.6 13.8 12.9 10.3 8.4 16.5 31.4 18.5 14.5 15.6 14.3 7.6 31.3 54.2 14.2 14.3 17.3 9.8 15.1 29.8 15.3 8.2 10.1 16.7 32.8 22.4 14.1 4.8 10.6 16.3 13.2 1.3 15.4 18.5 16.6 13.0 21.9 21.2 16.9 6.1 21.0 11.3 66.2 17.1 15.8 10.6 19.7 18.9 15.8 28.8 16.6 22.2 16.0 10.1 16.6 12.3 17.2 26.6 19.1 18.4 70.0 6.6 17.1 10.3 30.9 6.6 13.0 17.3 16.4 13.3 14.1 15.0 16.8 XPO1 "CRM-1, CRM1, emb" ENSG00000082898 "Exportin 1" O14980 2 61476032-61538741 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Transport" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010184, HPA042933" Supported Enhanced "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA 410000 "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "CAB010184: AB_2215817, HPA042933: AB_2678229" "unprognostic (7.34e-2)" "unprognostic (7.04e-2)" "unprognostic (6.37e-2)" "unprognostic (1.67e-2)" "unprognostic (5.61e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.84e-1)" "unprognostic (1.99e-3)" "unprognostic (4.43e-1)" "unprognostic (3.53e-3)" "unprognostic (4.90e-2)" "prognostic unfavorable (3.74e-4)" "unprognostic (5.69e-2)" "unprognostic (2.08e-1)" "unprognostic (2.43e-1)" "unprognostic (5.55e-2)" 33.2 29.8 30.1 48.7 31.4 25.8 39.2 35.7 44.3 37.9 31.6 34.9 24.7 52.5 37.0 35.1 45.9 32.0 36.0 27.9 33.7 30.8 41.7 31.9 65.3 28.9 30.5 58.9 26.2 38.5 22.0 52.1 30.4 34.2 42.0 52.0 19.9 34.9 37.5 34.2 33.2 48.6 30.9 43.4 31.9 54.5 32.8 73.6 38.8 47.2 60.9 38.6 22.4 38.9 169.1 152.9 194.1 135.8 91.4 107.9 145.5 166.6 109.2 192.9 151.8 217.3 114.7 256.0 117.4 127.1 186.3 125.0 307.9 126.5 268.6 151.6 110.7 242.8 136.2 148.4 55.4 234.6 145.4 62.9 103.8 149.4 145.9 126.0 149.5 108.7 285.5 127.7 164.9 97.8 212.6 100.4 213.1 189.9 111.5 175.6 208.0 148.1 103.0 124.9 152.8 77.5 174.2 142.8 87.1 185.6 108.6 110.8 98.9 153.7 178.7 137.2 175.0 102.8 203.2 347.0 96.8 214.0 151.0 3.3 1.4 2.2 1.8 2.2 1.9 1.1 1.0 1.8 2.1 0.7 1.0 1.0 0.6 2.7 1.2 1.6 1.2 1.2 30.1 31.4 35.7 44.3 27.9 33.7 28.9 30.5 30.4 30.9 32.8 38.9 42.0 41.7 43.2 114.3 55.3 52.1 32.1 45.5 78.6 67.5 40.2 38.6 64.5 38.6 38.7 31.3 95.9 54.1 56.6 27.3 13.7 29.7 4.2 58.6 79.7 47.7 45.1 73.2 87.9 26.1 49.3 49.9 42.3 68.6 41.8 100.4 41.4 55.8 57.2 72.3 101.3 34.2 40.7 55.3 58.4 11.9 33.5 63.9 37.4 68.4 64.2 33.4 61.8 83.4 102.5 32.3 20.9 30.9 57.2 55.6 21.0 22.2 56.9 101.7 19.7 50.5 55.7 65.9 91.6 83.3 56.8 30.1 54.5 54.4 46.2 47.7 YIF1A "54TM, FinGER7, YIF1, YIF1P" ENSG00000174851 "Yip1 interacting factor homolog A, membrane trafficking protein" O95070 11 66284580-66289145 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014840, HPA076194" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "HPA014840: AB_2217189, HPA076194: " "unprognostic (9.35e-2)" "unprognostic (7.86e-2)" "unprognostic (1.37e-1)" "unprognostic (1.94e-1)" "unprognostic (3.23e-1)" "unprognostic (4.38e-3)" "unprognostic (2.25e-3)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (2.13e-1)" "unprognostic (6.39e-3)" "unprognostic (1.35e-1)" "unprognostic (2.60e-2)" "unprognostic (2.03e-1)" "unprognostic (2.64e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (8.70e-4)" 49.2 54.7 33.4 28.4 36.0 16.7 47.5 38.5 41.4 42.7 42.4 50.8 56.5 53.5 34.5 50.9 45.7 25.5 57.8 33.5 35.6 50.9 149.5 44.9 22.9 38.9 36.1 42.1 86.0 40.6 74.1 34.5 38.2 47.3 37.7 12.3 51.1 29.6 96.2 43.0 47.4 41.1 38.5 35.9 56.1 36.4 35.6 21.6 49.9 59.3 24.7 45.4 40.6 41.9 80.7 131.3 39.4 72.6 130.0 138.7 73.8 114.4 122.3 95.5 94.3 126.0 95.5 67.9 111.5 161.4 107.8 119.9 60.7 107.9 75.6 77.7 72.0 42.5 93.3 158.7 147.4 59.3 61.5 97.4 144.4 98.6 158.9 76.6 91.3 67.0 80.7 114.8 84.3 199.3 71.3 64.4 40.3 147.4 136.6 54.9 61.2 203.9 81.9 70.9 58.5 57.9 62.5 106.7 103.4 49.6 155.5 43.5 81.0 80.8 69.0 165.3 54.1 78.1 86.0 63.0 125.4 56.2 90.2 19.4 95.6 20.6 71.3 141.4 78.4 95.9 60.6 67.2 116.4 82.4 48.0 55.3 9.4 51.2 140.0 141.6 54.9 99.8 33.4 36.0 38.5 41.4 33.5 35.6 38.9 36.1 38.2 38.5 35.6 41.9 63.4 38.5 48.0 6.2 52.2 36.1 88.1 170.4 38.1 27.1 84.4 92.7 34.5 82.9 115.5 46.0 22.9 114.3 42.6 66.8 64.6 137.9 28.1 42.1 84.8 53.6 87.4 21.0 1.9 149.4 248.5 90.4 55.0 42.8 29.9 38.8 49.2 172.0 105.4 26.9 3.9 140.9 116.0 38.4 44.9 48.6 75.5 45.0 72.9 8.4 40.8 73.7 28.8 10.1 10.4 132.1 93.3 82.4 92.4 195.2 202.2 135.2 101.4 34.0 39.5 60.8 150.0 61.0 56.8 63.3 46.3 154.3 36.5 88.1 107.2 112.1 YIPF5 "FinGER5, SMAP-5" ENSG00000145817 "Yip1 domain family member 5" Q969M3 5 144158162-144170714 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 236.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042338, HPA073622" Supported Supported "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Golgi apparatus, Vesicles" Nucleoplasm "HPA042338: AB_2677953, HPA073622: AB_2686618" "prognostic unfavorable (7.83e-5)" "unprognostic (1.13e-3)" "unprognostic (1.95e-2)" "unprognostic (8.35e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.12e-5)" "prognostic unfavorable (3.26e-5)" "unprognostic (2.89e-2)" "unprognostic (1.99e-1)" "unprognostic (3.64e-2)" "unprognostic (1.20e-3)" "unprognostic (4.79e-2)" "unprognostic (8.79e-2)" "unprognostic (1.69e-1)" "unprognostic (1.24e-2)" "unprognostic (5.11e-2)" "unprognostic (6.49e-2)" 22.2 20.4 8.3 17.7 9.8 21.0 24.1 9.8 11.0 24.7 16.3 25.8 30.5 20.2 21.2 28.6 20.3 21.4 18.1 9.5 12.5 25.4 31.7 20.3 18.9 9.7 10.3 20.6 32.0 25.7 17.0 30.2 11.5 18.3 26.0 20.6 26.2 19.2 9.3 17.7 27.3 28.5 10.3 15.5 22.7 20.9 10.3 16.1 22.6 14.5 23.9 24.0 14.3 12.0 43.2 28.2 36.0 28.6 84.4 90.5 32.9 143.6 96.9 63.2 101.5 45.3 44.0 23.5 67.3 156.9 72.5 38.7 34.7 70.5 84.8 32.9 30.2 17.4 44.9 46.7 68.0 39.3 27.7 69.1 64.3 56.8 46.3 108.9 61.0 25.6 18.8 38.5 86.4 22.5 19.4 22.2 23.3 27.5 30.7 20.3 53.4 39.3 39.4 37.7 24.4 30.0 49.7 26.4 66.5 36.2 54.9 25.5 236.7 74.0 35.8 72.5 57.2 34.7 61.8 29.9 70.7 36.9 55.2 48.9 34.5 48.7 47.2 47.4 53.1 37.9 47.1 52.4 41.2 36.4 49.0 46.3 26.0 41.0 44.7 45.0 62.8 40.6 8.3 9.8 9.8 11.0 9.5 12.5 9.7 10.3 11.5 10.3 10.3 12.0 43.5 38.5 27.4 8.5 35.6 29.4 24.5 49.4 26.2 40.6 33.4 29.6 21.8 31.5 35.9 20.2 33.3 56.7 40.5 33.0 31.3 43.7 14.9 31.4 49.8 44.1 14.8 20.0 19.7 68.3 77.1 51.9 33.6 31.2 36.8 34.1 30.4 34.7 36.5 33.7 16.9 50.1 22.4 34.0 24.4 7.3 35.4 28.7 30.2 6.5 38.3 54.9 27.8 13.6 16.2 60.5 35.5 33.8 70.0 23.4 56.0 36.1 50.6 53.8 39.5 31.8 45.4 83.9 56.0 33.4 26.0 67.5 42.0 41.1 27.4 24.5 ZDHHC13 "FLJ10852, FLJ10941, HIP14L" ENSG00000177054 "Zinc finger DHHC-type palmitoyltransferase 13" Q8IUH4 11 19117099-19176422 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 120.5;Urothelial cells: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 136.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016759, HPA018791" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "Golgi apparatus" "HPA016759: AB_1858993, HPA018791: AB_1858992" "unprognostic (1.43e-2)" "unprognostic (4.00e-3)" "unprognostic (1.08e-1)" "unprognostic (1.11e-3)" "unprognostic (2.95e-2)" "unprognostic (1.34e-2)" "unprognostic (1.55e-2)" "unprognostic (1.57e-1)" "unprognostic (3.57e-3)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (6.95e-3)" "unprognostic (1.15e-1)" "unprognostic (7.93e-2)" "unprognostic (2.17e-1)" "unprognostic (2.76e-2)" 4.8 5.7 5.2 7.8 5.2 9.7 8.9 6.6 7.1 9.3 6.6 16.9 11.2 6.7 5.1 37.2 12.9 8.7 9.1 5.4 5.7 9.2 2.2 6.1 9.6 5.5 5.0 5.3 11.2 14.9 11.7 6.2 5.8 8.2 18.2 16.1 10.2 5.4 1.6 18.8 11.3 6.1 5.3 5.7 18.5 14.4 5.0 11.7 8.7 2.9 22.4 22.4 15.4 5.2 41.6 19.3 18.0 15.5 6.3 7.2 17.3 19.4 17.8 21.3 24.4 11.7 9.7 21.1 13.1 16.3 47.9 61.3 26.0 12.8 23.3 26.4 22.6 11.1 12.6 9.7 14.6 15.2 18.5 8.3 14.7 9.0 12.5 19.9 136.8 28.9 10.7 10.3 22.1 13.5 19.6 12.2 15.1 38.7 17.6 21.3 25.0 5.0 21.9 27.0 31.3 23.0 23.2 28.0 10.7 17.3 13.2 17.6 39.6 18.9 13.2 29.2 15.8 8.7 28.5 19.2 22.6 15.5 33.6 11.6 4.7 32.7 8.5 7.9 7.8 8.7 6.6 9.6 5.9 5.5 6.2 8.3 6.0 6.3 6.4 5.6 9.4 4.6 5.2 5.2 6.6 7.1 5.4 5.7 5.5 5.0 5.8 5.3 5.0 5.2 8.1 9.6 10.7 28.7 9.6 24.2 22.3 27.2 14.2 12.0 7.5 4.8 34.1 12.8 41.3 16.5 10.4 8.7 10.6 20.1 5.9 25.1 120.5 21.5 6.6 11.3 15.6 11.6 27.2 19.2 18.8 9.2 24.5 30.8 12.0 16.2 12.8 0.9 6.1 16.8 34.9 24.7 36.7 6.8 8.3 46.6 7.8 6.2 3.6 9.4 20.8 52.8 18.6 19.6 20.9 20.4 16.4 2.2 10.4 47.4 15.5 3.5 57.0 8.8 0.0 5.4 7.4 58.1 31.7 21.3 36.2 6.3 11.4 7.7 21.4 103.0 ZDHHC17 "HIP14, HYPH, KIAA0946" ENSG00000186908 "Zinc finger DHHC-type palmitoyltransferase 17" Q8IUH5 12 76764103-76853696 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 102.2;Inhibitory neurons: 95.1;Oligodendrocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 17.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016807, HPA058674" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 65: Plasmacytoid DCs - Unknown function" "Golgi apparatus, Vesicles" "HPA016807: AB_1858999, HPA058674: AB_2732626" "unprognostic (1.06e-1)" "unprognostic (2.26e-2)" "unprognostic (2.63e-2)" "unprognostic (3.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.83e-2)" "unprognostic (2.35e-3)" "unprognostic (3.09e-1)" "unprognostic (8.38e-2)" "unprognostic (1.04e-1)" "unprognostic (1.56e-3)" "unprognostic (5.42e-2)" "prognostic unfavorable (7.11e-5)" "unprognostic (1.77e-2)" "unprognostic (2.69e-1)" "unprognostic (2.98e-1)" "unprognostic (1.71e-2)" 15.6 14.1 18.6 12.1 20.4 23.7 16.1 23.1 25.9 15.8 11.8 13.7 7.5 21.7 12.3 8.0 12.8 10.5 12.5 19.8 18.9 11.0 9.8 10.6 14.8 18.2 18.6 20.1 10.2 12.7 11.0 16.4 18.9 14.1 10.1 31.0 8.1 12.8 11.8 10.2 10.3 14.6 19.2 14.4 8.5 12.8 19.4 14.9 11.8 14.2 11.4 11.7 11.7 27.8 8.2 9.5 30.1 15.4 17.6 18.5 14.6 16.2 13.4 10.5 9.2 7.8 5.8 11.2 9.5 15.9 10.5 7.5 12.1 10.1 16.2 9.5 12.6 16.4 13.1 12.0 11.9 16.5 13.9 17.6 10.3 10.0 14.7 35.2 12.2 15.2 18.0 5.2 13.8 7.6 12.0 21.9 22.1 3.6 11.3 16.1 10.7 12.3 12.0 12.3 11.7 20.1 17.8 6.4 10.7 25.7 14.4 16.3 16.9 14.3 11.0 8.8 9.3 8.1 8.5 11.9 5.4 7.6 15.0 6.2 2.3 5.7 3.6 2.4 2.9 2.5 2.9 2.6 2.8 3.9 3.0 2.5 5.9 2.0 2.5 17.1 1.3 1.5 18.6 20.4 23.1 25.9 19.8 18.9 18.2 18.6 18.9 19.2 19.4 27.8 33.4 32.1 18.3 75.7 20.1 7.1 10.4 9.8 12.5 54.6 9.9 10.7 21.3 12.8 15.5 12.9 39.6 20.3 74.1 5.0 0.0 8.0 11.3 11.8 23.8 24.8 19.2 12.0 102.2 4.7 10.2 21.2 7.1 10.1 41.2 20.7 20.3 10.6 8.8 28.6 95.1 7.5 8.2 12.3 19.4 13.7 20.2 14.9 5.4 54.4 14.9 26.1 18.6 88.4 115.8 6.8 4.5 21.1 13.5 10.2 8.4 5.5 18.0 38.1 0.0 32.3 22.0 17.7 22.6 9.5 5.5 5.6 18.1 19.6 6.2 5.5 ZNF638 "MGC26130, NP220, ZFML, Zfp638" ENSG00000075292 "Zinc finger protein 638" Q14966 2 71276561-71435069 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 342.3;Oligodendrocytes: 619.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036784, HPA057395" Supported Enhanced Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" Nucleoplasm Vesicles "HPA036784: AB_10672478, HPA057395: AB_2683426" "unprognostic (2.58e-2)" "unprognostic (3.15e-1)" "unprognostic (7.57e-2)" "unprognostic (1.26e-3)" "unprognostic (2.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.35e-2)" "unprognostic (5.68e-3)" "unprognostic (2.31e-2)" "unprognostic (1.11e-1)" "unprognostic (1.69e-1)" "unprognostic (1.32e-1)" "unprognostic (2.66e-3)" "unprognostic (3.28e-1)" "unprognostic (7.68e-2)" "unprognostic (1.93e-2)" "prognostic favorable (8.73e-5)" 21.1 22.1 35.7 21.6 48.9 28.2 24.6 77.6 52.3 23.0 37.7 22.0 15.6 29.2 18.4 19.8 22.1 19.1 41.0 35.7 41.3 24.2 30.9 21.2 25.0 41.9 36.8 37.3 21.9 27.9 24.9 23.2 41.9 22.2 19.5 48.6 21.0 19.5 51.5 16.8 19.0 22.9 34.8 23.1 21.8 29.7 38.9 30.9 29.8 33.7 22.6 21.3 17.1 82.5 36.2 51.0 77.0 36.1 44.4 48.3 59.2 40.4 46.6 33.6 30.0 49.2 34.6 59.2 36.6 37.1 52.3 29.9 72.1 41.4 48.7 60.5 40.1 77.8 54.8 45.4 38.3 72.0 50.6 30.8 39.5 36.1 66.7 47.8 52.5 39.2 79.4 33.8 49.6 36.1 50.9 52.9 66.7 54.1 32.4 43.0 116.5 41.7 36.0 54.3 59.0 38.7 49.8 34.7 52.8 76.3 32.3 43.7 54.3 41.4 60.0 31.1 41.2 27.6 45.7 57.4 34.8 46.3 45.8 64.1 17.0 33.5 18.1 16.3 17.2 25.4 17.1 17.2 14.0 26.0 22.5 16.7 29.1 21.5 24.1 17.7 16.0 10.8 35.7 48.9 77.6 52.3 35.7 41.3 41.9 36.8 41.9 34.8 38.9 82.5 63.1 67.3 112.4 227.9 63.9 31.7 56.8 40.8 46.1 111.5 36.8 35.4 107.0 27.1 59.0 40.5 123.0 42.5 46.7 39.2 19.6 43.0 15.7 54.2 63.7 65.9 38.4 57.2 286.9 40.9 29.0 83.5 50.0 59.2 79.1 112.8 38.6 48.6 32.5 67.3 268.4 34.2 32.6 41.9 33.3 15.8 75.2 49.6 23.2 225.8 71.6 56.4 56.7 342.3 619.5 39.6 35.7 63.9 50.5 60.0 38.1 21.6 74.7 104.0 32.9 98.3 73.1 110.1 78.3 37.4 30.3 50.2 56.1 74.0 36.8 58.9